Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 3375
• Symbol: IAPP
• Description: islet amyloid polypeptide

DataSource: http://genomecrispr.dkfz.de/#!/results/IAPP

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
21373405	21373428	12	-	26472758	Jiyoye	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.6334512373295494	[211]	[247]	4	hSpCas9	negative selection	75521
21378311	21378334	12	-	26472758	Jiyoye	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	-2.2090832497048214	[232]	[37]	-8	hSpCas9	negative selection	75522
21378403	21378426	12	-	26472758	Jiyoye	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.7254152893631217	[234]	[292]	5	hSpCas9	negative selection	75523
21378225	21378248	12	+	26472758	Jiyoye	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	1.7212839719339366	[73]	[183]	8	hSpCas9	negative selection	75524
21378233	21378256	12	+	26472758	Jiyoye	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.6652435344463179	[96]	[115]	5	hSpCas9	negative selection	75525
21378344	21378367	12	-	26472758	Jiyoye	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	0.1549016705098638	[186]	[156]	1	hSpCas9	negative selection	75526
21378353	21378376	12	+	26472758	Jiyoye	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.09705584710242579	[138]	[97]	0	hSpCas9	negative selection	75527
21378269	21378292	12	-	26472758	Jiyoye	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	0.3891789522120276	[241]	[238]	3	hSpCas9	negative selection	75528
21378331	21378354	12	+	26472758	Jiyoye	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.47946424231275286	[252]	[265]	3	hSpCas9	negative selection	75529
21378366	21378389	12	+	26472758	Jiyoye	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.8644979426017931	[267]	[110]	-6	hSpCas9	negative selection	75530
21373405	21373428	12	-	26472758	KBM7	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.7440213107058669	[574,687]	[536,474]	7	hSpCas9	negative selection	266639
21378311	21378334	12	-	26472758	KBM7	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	0.3013772700434212	[326,379]	[199,213]	3	hSpCas9	negative selection	266640
21378403	21378426	12	-	26472758	KBM7	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.5465938041541197	[1083,808]	[793,508]	6	hSpCas9	negative selection	266641
21378225	21378248	12	+	26472758	KBM7	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.5416881913725833	[539,605]	[520,284]	6	hSpCas9	negative selection	266642
21378233	21378256	12	+	26472758	KBM7	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.8079082463105371	[539,571]	[569,363]	8	hSpCas9	negative selection	266643
21378344	21378367	12	-	26472758	KBM7	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	0.13966692156709487	[734,591]	[396,291]	1	hSpCas9	negative selection	266644
21378353	21378376	12	+	26472758	KBM7	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.466388338623994	[734,706]	[521,422]	5	hSpCas9	negative selection	266645
21378269	21378292	12	-	26472758	KBM7	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	0.7558367111949076	[859,1045]	[722,807]	8	hSpCas9	negative selection	266646
21378331	21378354	12	+	26472758	KBM7	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.09652644925755505	[1606,1774]	[781,926]	0	hSpCas9	negative selection	266647
21378366	21378389	12	+	26472758	KBM7	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.5936226590805767	[809,910]	[345,203]	-5	hSpCas9	negative selection	266648
21373405	21373428	12	-	26472758	Raji	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.6367537101314382	[290]	[104]	6	hSpCas9	negative selection	457757
21378311	21378334	12	-	26472758	Raji	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	-0.375009231707009	[189]	[33]	-3	hSpCas9	negative selection	457758
21378403	21378426	12	-	26472758	Raji	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.9848614031620788	[478]	[219]	8	hSpCas9	negative selection	457759
21378225	21378248	12	+	26472758	Raji	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.7381497257078804	[278]	[107]	7	hSpCas9	negative selection	457760
21378233	21378256	12	+	26472758	Raji	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.39530911674910396	[248]	[75]	4	hSpCas9	negative selection	457761
21378344	21378367	12	-	26472758	Raji	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	0.5326893701062703	[279]	[93]	5	hSpCas9	negative selection	457762
21378353	21378376	12	+	26472758	Raji	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.013261358009049484	[379]	[88]	0	hSpCas9	negative selection	457763
21378269	21378292	12	-	26472758	Raji	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	0.36213846344282685	[465]	[138]	3	hSpCas9	negative selection	457764
21378331	21378354	12	+	26472758	Raji	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.8249346339006987	[792]	[325]	7	hSpCas9	negative selection	457765
21378366	21378389	12	+	26472758	Raji	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.3099349051564828	[421]	[78]	-3	hSpCas9	negative selection	457766
21373405	21373428	12	-	26472758	K562	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.3620582119050646	[717]	[778]	3	hSpCas9	negative selection	648875
21378311	21378334	12	-	26472758	K562	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	1.2648828302261625	[244]	[496]	9	hSpCas9	negative selection	648876
21378403	21378426	12	-	26472758	K562	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.49539506785702714	[820]	[976]	4	hSpCas9	negative selection	648877
21378225	21378248	12	+	26472758	K562	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.8559999731947472	[357]	[546]	7	hSpCas9	negative selection	648878
21378233	21378256	12	+	26472758	K562	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.4777057901061888	[489]	[575]	4	hSpCas9	negative selection	648879
21378344	21378367	12	-	26472758	K562	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	0.8334856267203395	[467]	[703]	7	hSpCas9	negative selection	648880
21378353	21378376	12	+	26472758	K562	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.5379552218975847	[584]	[716]	4	hSpCas9	negative selection	648881
21378269	21378292	12	-	26472758	K562	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	0.8380742027913572	[716]	[1081]	7	hSpCas9	negative selection	648882
21378331	21378354	12	+	26472758	K562	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.4173769093456139	[1530]	[1725]	3	hSpCas9	negative selection	648883
21378366	21378389	12	+	26472758	K562	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.16008131737838338	[772]	[583]	-1	hSpCas9	negative selection	648884
21378225	21378248	12	+	26627737	DLD1	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.2511578784442051	[405]	[181,102,163]	2	hSpCas9	negative selection	783286
21378270	21378293	12	+	26627737	DLD1	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.7881604677653632	[313]	[237,66,194]	7	hSpCas9	negative selection	783287
21378329	21378352	12	-	26627737	DLD1	viability	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.29908628259386943	[428]	[120,111,246]	3	hSpCas9	negative selection	783288
21378225	21378248	12	+	26627737	GBM cells	viability after 5 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.08365375474273518	[365]	[198,216]	1	hSpCas9	negative selection	865601
21378270	21378293	12	+	26627737	GBM cells	viability after 5 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.6391820207974963	[211]	[66,78]	-7	hSpCas9	negative selection	865602
21378329	21378352	12	-	26627737	GBM cells	viability after 5 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.4774501064474086	[374]	[271,287]	7	hSpCas9	negative selection	865603
21378225	21378248	12	+	26627737	GBM cells	viability after 13 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.21865738361773468	[365]	[256,209]	3	hSpCas9	negative selection	947916
21378270	21378293	12	+	26627737	GBM cells	viability after 13 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.6067102426652797	[211]	[117,40]	-6	hSpCas9	negative selection	947917
21378329	21378352	12	-	26627737	GBM cells	viability after 13 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.17882827168559623	[374]	[317,158]	2	hSpCas9	negative selection	947918
21378225	21378248	12	+	26627737	GBM cells	viability after 21 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.11033848368162957	[365]	[222,206]	1	hSpCas9	negative selection	1030231
21378270	21378293	12	+	26627737	GBM cells	viability after 21 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-1.1837733128315626	[211]	[45,54]	-7	hSpCas9	negative selection	1030232
21378329	21378352	12	-	26627737	GBM cells	viability after 21 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.2313590350743091	[374]	[246,231]	2	hSpCas9	negative selection	1030233
21378225	21378248	12	+	26627737	RPE1	viability after 9 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-1.273343436933763	[1297]	[130,215]	-7	hSpCas9	negative selection	1112546
21378270	21378293	12	+	26627737	RPE1	viability after 9 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	1.2230071377497425	[469]	[239,476]	7	hSpCas9	negative selection	1112547
21378329	21378352	12	-	26627737	RPE1	viability after 9 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.7689262135830617	[630]	[333,339]	5	hSpCas9	negative selection	1112548
21378225	21378248	12	+	26627737	RPE1	viability after 12 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.7307366471287746	[1297]	[146,276]	-5	hSpCas9	negative selection	1194861
21378270	21378293	12	+	26627737	RPE1	viability after 12 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	1.30974499886855	[469]	[262,365]	7	hSpCas9	negative selection	1194862
21378329	21378352	12	-	26627737	RPE1	viability after 12 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.9610623341909642	[630]	[330,328]	6	hSpCas9	negative selection	1194863
21378225	21378248	12	+	26627737	RPE1	viability after 15 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.8384434693321238	[1297]	[157,250]	-5	hSpCas9	negative selection	1277176
21378270	21378293	12	+	26627737	RPE1	viability after 15 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	1.801516606945861	[469]	[465,460]	8	hSpCas9	negative selection	1277177
21378329	21378352	12	-	26627737	RPE1	viability after 15 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.9528512615087447	[630]	[400,291]	6	hSpCas9	negative selection	1277178
21378225	21378248	12	+	26627737	RPE1	viability after 18 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-1.1537845729176603	[1297]	[140,174]	-6	hSpCas9	negative selection	1359491
21378270	21378293	12	+	26627737	RPE1	viability after 18 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	1.1514898482690077	[469]	[201,366]	6	hSpCas9	negative selection	1359492
21378329	21378352	12	-	26627737	RPE1	viability after 18 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.2694521170822493	[630]	[270,134]	1	hSpCas9	negative selection	1359493
21378225	21378248	12	+	26627737	HeLa	viability after 8 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.4382930131956988	[533]	[155,256,102]	-4	hSpCas9	negative selection	1441806
21378270	21378293	12	+	26627737	HeLa	viability after 8 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.2825988042456148	[232]	[200,120,68]	2	hSpCas9	negative selection	1441807
21378329	21378352	12	-	26627737	HeLa	viability after 8 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	-0.025662476946447216	[359]	[176,109,177]	0	hSpCas9	negative selection	1441808
21378225	21378248	12	+	26627737	HeLa	viability after 12 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.3745202730321005	[533]	[183,170,155]	-3	hSpCas9	negative selection	1524121
21378270	21378293	12	+	26627737	HeLa	viability after 12 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.36435523243571344	[232]	[58,111,48]	-3	hSpCas9	negative selection	1524122
21378329	21378352	12	-	26627737	HeLa	viability after 12 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.8993312639642492	[359]	[364,173,306]	7	hSpCas9	negative selection	1524123
21378225	21378248	12	+	26627737	HeLa	viability after 15 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.3076878439662435	[533]	[93,257,175]	-3	hSpCas9	negative selection	1606436
21378270	21378293	12	+	26627737	HeLa	viability after 15 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.7777901211215332	[232]	[79,281,123]	6	hSpCas9	negative selection	1606437
21378329	21378352	12	-	26627737	HeLa	viability after 15 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.4110667505032046	[359]	[170,193,221]	3	hSpCas9	negative selection	1606438
21378225	21378248	12	+	26627737	HeLa	viability after 18 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.3000035765512833	[533]	[62,215,175]	-3	hSpCas9	negative selection	1688751
21378270	21378293	12	+	26627737	HeLa	viability after 18 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.8205667061584596	[232]	[53,244,123]	6	hSpCas9	negative selection	1688752
21378329	21378352	12	-	26627737	HeLa	viability after 18 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.4001976588424643	[359]	[109,162,221]	3	hSpCas9	negative selection	1688753
21378225	21378248	12	+	26627737	HCT116	viability after 6 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.22274302381578753	[802]	[272,77]	1	hSpCas9	negative selection	1771066
21378270	21378293	12	+	26627737	HCT116	viability after 6 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.9531901130347217	[263]	[80,79]	5	hSpCas9	negative selection	1771067
21378329	21378352	12	-	26627737	HCT116	viability after 6 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.812531546387038	[570]	[98,189]	4	hSpCas9	negative selection	1771068
21378225	21378248	12	+	26627737	HCT116	viability after 8 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.27225349272866783	[290]	[194,193,191]	3	hSpCas9	negative selection	1853381
21378270	21378293	12	+	26627737	HCT116	viability after 8 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.3920308941489278	[158]	[115,119,108]	4	hSpCas9	negative selection	1853382
21378329	21378352	12	-	26627737	HCT116	viability after 8 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.38252757709712054	[295]	[284,209,144]	4	hSpCas9	negative selection	1853383
21378225	21378248	12	+	26627737	HCT116	viability after 9 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.6618332781647469	[802]	[317,355]	5	hSpCas9	negative selection	1935696
21378270	21378293	12	+	26627737	HCT116	viability after 9 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.9369298289910227	[263]	[163,111]	6	hSpCas9	negative selection	1935697
21378329	21378352	12	-	26627737	HCT116	viability after 9 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	-0.2320903964009109	[570]	[164,101]	-2	hSpCas9	negative selection	1935698
21378225	21378248	12	+	26627737	HCT116	viability after 12 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.03381353048943115	[290]	[164,200,103]	0	hSpCas9	negative selection	2018011
21378270	21378293	12	+	26627737	HCT116	viability after 12 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.2575689147886454	[158]	[93,91,113]	2	hSpCas9	negative selection	2018012
21378329	21378352	12	-	26627737	HCT116	viability after 12 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.5347014350116113	[295]	[188,215,273]	5	hSpCas9	negative selection	2018013
21378225	21378248	12	+	26627737	HCT116	viability after 15 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.48767116045982795	[290]	[123,366,198]	4	hSpCas9	negative selection	2100326
21378270	21378293	12	+	26627737	HCT116	viability after 15 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.40496397945622864	[158]	[143,0,70]	-4	hSpCas9	negative selection	2100327
21378329	21378352	12	-	26627737	HCT116	viability after 15 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.5306006285604953	[295]	[298,183,259]	5	hSpCas9	negative selection	2100328
21378225	21378248	12	+	26627737	HCT116	viability after 18 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.1223718627704378	[290]	[110,173,173]	1	hSpCas9	negative selection	2182641
21378270	21378293	12	+	26627737	HCT116	viability after 18 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.5273127955383761	[158]	[148,3,189]	4	hSpCas9	negative selection	2182642
21378329	21378352	12	-	26627737	HCT116	viability after 18 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.7602976609828039	[295]	[197,244,285]	6	hSpCas9	negative selection	2182643
21372694	21372717	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGTGTCCTTGTGCAGTTAATGG	IAPP	ENSG00000121351	-0.34726945977258294	[888,213]	[127,57]	-2	dCas9-VP64	positive selection	2383974
21372688	21372711	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GACACACCATTAACTGCACAAGG	IAPP	ENSG00000121351	2.344639801218315	[150,168]	[37,331]	7	dCas9-VP64	positive selection	2383975
21372768	21372791	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	TACCTCACAGGCAGCAGAAGCGG	IAPP	ENSG00000121351	1.8273066010396786	[95,82]	[95,41]	6	dCas9-VP64	positive selection	2383976
21372694	21372717	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGTGTCCTTGTGCAGTTAATGG	IAPP	ENSG00000121351	-0.8386885156924393	[238,439]	[62,59]	-7	dCas9-VP64	positive selection	2479229
21372688	21372711	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GACACACCATTAACTGCACAAGG	IAPP	ENSG00000121351	0.8232686100194362	[437,348]	[116,330]	5	dCas9-VP64	positive selection	2479230
21372768	21372791	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	TACCTCACAGGCAGCAGAAGCGG	IAPP	ENSG00000121351	1.255470721468534	[266,319]	[220,234]	7	dCas9-VP64	positive selection	2479231
21373405	21373428	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.3477860366281823	[4,4]	[4,5]	7	hSpCas9	positive selection	2994610
21378234	21378257	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.4493609792166761	[3,3]	[1,5]	8	hSpCas9	positive selection	2994611
21378226	21378249	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.12100268712345251	[4,4]	[3,2]	-2	hSpCas9	positive selection	2994612
21373411	21373434	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.49590768944397906	[4,4]	[5,6]	8	hSpCas9	positive selection	2994613
21373405	21373428	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.19410187179813793	[4,4]	[4,3]	3	hSpCas9	positive selection	3062468
21378234	21378257	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.12371328127548739	[3,3]	[3,1]	2	hSpCas9	positive selection	3062469
21378226	21378249	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.30211126638819397	[4,4]	[3,3]	5	hSpCas9	positive selection	3062470
21373411	21373434	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.2322786490542988	[4,4]	[4,3]	4	hSpCas9	positive selection	3062471
21373421	21373444		-	24336571	A375	resistance to PLX after 7 days	AAAGTTACCAACCTTTCAATGGG	IAPP	ENSG00000121351	-0.041486703278779735	[11,11]	[10,11]	-1	hSpCas9	positive selection	3120199
21378270	21378293		+	24336571	A375	resistance to PLX after 7 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.2590568194405978	[9,14]	[9,9]	-7	hSpCas9	positive selection	3120200
21378329	21378352		-	24336571	A375	resistance to PLX after 7 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	-0.27479796816650204	[6,6]	[5,5]	-7	hSpCas9	positive selection	3120201
21373410	21373433		+	24336571	A375	resistance to PLX after 7 days	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	-0.33093906205617646	[9,8]	[6,7]	-8	hSpCas9	positive selection	3120202
21373421	21373444		-	24336571	A375	resistance to PLX after 14 days	AAAGTTACCAACCTTTCAATGGG	IAPP	ENSG00000121351	-0.18645699197144414	[10,13]	[3,4]	-2	hSpCas9	positive selection	3177992
21378270	21378293		+	24336571	A375	resistance to PLX after 14 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.3358188982742888	[7,5]	[5,1]	3	hSpCas9	positive selection	3177993
21378329	21378352		-	24336571	A375	resistance to PLX after 14 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.41229698782231067	[6,7]	[4,3]	4	hSpCas9	positive selection	3177994
21373410	21373433		+	24336571	A375	resistance to PLX after 14 days	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.0036322672676691453	[11,11]	[3,5]	0	hSpCas9	positive selection	3177995
21373421	21373444		-	24336571	A375	viability after 7 days	AAAGTTACCAACCTTTCAATGGG	IAPP	ENSG00000121351	-0.32131307230647266	[15]	[11,11]	-4	hSpCas9	negative selection	3235785
21378270	21378293		+	24336571	A375	viability after 7 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.45217653737765623	[8]	[9,14]	7	hSpCas9	negative selection	3235786
21378329	21378352		-	24336571	A375	viability after 7 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	-0.27264545250795547	[8]	[6,6]	-4	hSpCas9	negative selection	3235787
21373410	21373433		+	24336571	A375	viability after 7 days	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	-0.32399110399013425	[12]	[9,8]	-4	hSpCas9	negative selection	3235788
21373421	21373444		-	24336571	A375	viability after 14 days	AAAGTTACCAACCTTTCAATGGG	IAPP	ENSG00000121351	-0.23755195483545596	[15]	[10,13]	-3	hSpCas9	negative selection	3293578
21378270	21378293		+	24336571	A375	viability after 14 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.32877937184176603	[8]	[7,5]	-4	hSpCas9	negative selection	3293579
21378329	21378352		-	24336571	A375	viability after 14 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	-0.14426293866652473	[8]	[6,7]	-2	hSpCas9	negative selection	3293580
21373410	21373433		+	24336571	A375	viability after 14 days	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	-0.044007120513085626	[12]	[11,11]	0	hSpCas9	negative selection	3293581
21373405	21373428	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	2.556886493304743	[25,25]	[0,0]	8	hSpCas9	positive selection	3373608
21378304	21378327	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	-0.8459615969661868	[274,274]	[0,0]	-6	hSpCas9	positive selection	3373609
21378353	21378376	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.3573836326693731	[195,195]	[0,0]	-2	hSpCas9	positive selection	3373610
21373405	21373428	12	-	26780180	HT29	viability (Avana library 4 designs)	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.120198761916763	[]	[]	0	hSpCas9	negative selection	3431946
21378233	21378256	12	+	26780180	HT29	viability (Avana library 4 designs)	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	1.80927502740018	[]	[]	7	hSpCas9	negative selection	3431947
21378225	21378248	12	+	26780180	HT29	viability (Avana library 4 designs)	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.278098663754047	[]	[]	-4	hSpCas9	negative selection	3431948
21373410	21373433	12	+	26780180	HT29	viability (Avana library 4 designs)	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.186354801549487	[]	[]	0	hSpCas9	negative selection	3431949
21373410	21373433	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.861302122256798	[]	[]	1	hSpCas9	negative selection	3517857
21378233	21378256	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	3.4550703586091	[]	[]	5	hSpCas9	negative selection	3517858
21373405	21373428	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	3.66373653301156	[]	[]	6	hSpCas9	negative selection	3517859
21378225	21378248	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.0142036573266102	[]	[]	0	hSpCas9	negative selection	3517860
21373421	21373444	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAAGTTACCAACCTTTCAATGGG	IAPP	ENSG00000121351	-4.86845871011233	[]	[]	-5	hSpCas9	negative selection	3517861
21373360	21373383	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGAAATACTTGCAGCTTCAGG	IAPP	ENSG00000121351	3.78697237156844	[]	[]	6	hSpCas9	negative selection	3517862
21373410	21373433	12	+	26780180	A375	viability (Avana lentiGuide)	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	-2.46210303018801	[]	[]	-4	hSpCas9	negative selection	3626516
21378233	21378256	12	+	26780180	A375	viability (Avana lentiGuide)	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	-4.86688223280904	[]	[]	-8	hSpCas9	negative selection	3626517
21373405	21373428	12	-	26780180	A375	viability (Avana lentiGuide)	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	1.56155240594669	[]	[]	1	hSpCas9	negative selection	3626518
21378225	21378248	12	+	26780180	A375	viability (Avana lentiGuide)	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.518727566260472	[]	[]	-1	hSpCas9	negative selection	3626519
21373421	21373444	12	-	26780180	A375	viability (Avana lentiGuide)	AAAGTTACCAACCTTTCAATGGG	IAPP	ENSG00000121351	-6.46306872695036	[]	[]	-9	hSpCas9	negative selection	3626520
21373360	21373383	12	-	26780180	A375	viability (Avana lentiGuide)	TGAGAAATACTTGCAGCTTCAGG	IAPP	ENSG00000121351	-3.46115292011752	[]	[]	-6	hSpCas9	negative selection	3626521
21373410	21373433	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.19881255298148537	[6]	[9,6]	5	hSpCas9	positive selection	3735175
21378233	21378256	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.22468514591754024	[4]	[5,5]	6	hSpCas9	positive selection	3735176
21373405	21373428	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.11060067249155087	[6]	[6,6]	3	hSpCas9	positive selection	3735177
21378225	21378248	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.23039974338217623	[5]	[4,3]	-4	hSpCas9	positive selection	3735178
21373421	21373444	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAAGTTACCAACCTTTCAATGGG	IAPP	ENSG00000121351	-0.3434653376113321	[6]	[5,4]	-5	hSpCas9	positive selection	3735179
21373360	21373383	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGAAATACTTGCAGCTTCAGG	IAPP	ENSG00000121351	0.1974387078231692	[6]	[7,7]	5	hSpCas9	positive selection	3735180
21373410	21373433	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.27155090601530946	[6]	[7,6]	7	hSpCas9	positive selection	3843782
21378233	21378256	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	-0.2657996840687604	[4]	[4,1]	-4	hSpCas9	positive selection	3843783
21373405	21373428	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.17399546184565468	[6]	[6,6]	4	hSpCas9	positive selection	3843784
21378225	21378248	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.21673103797761595	[6]	[5,6]	5	hSpCas9	positive selection	3843785
21373421	21373444	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAAGTTACCAACCTTTCAATGGG	IAPP	ENSG00000121351	0.3205713453090675	[5]	[6,5]	8	hSpCas9	positive selection	3843786
21373360	21373383	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGAAATACTTGCAGCTTCAGG	IAPP	ENSG00000121351	0.2779279646913655	[7]	[7,8]	7	hSpCas9	positive selection	3843787
21373405	21373428	12	-	26780180	A375	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.514360479874727	[]	[]	1	hSpCas9	negative selection	3949766
21378270	21378293	12	+	26780180	A375	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.898999629963054	[]	[]	4	hSpCas9	negative selection	3949767
21378353	21378376	12	+	26780180	A375	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	1.1719423370968	[]	[]	6	hSpCas9	negative selection	3949768
21378304	21378327	12	+	26780180	A375	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	1.10886639917331	[]	[]	5	hSpCas9	negative selection	3949769
21378403	21378426	12	-	26780180	A375	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.691169926297866	[]	[]	2	hSpCas9	negative selection	3949770
21373410	21373433	12	+	26780180	A375	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.917197952867821	[]	[]	4	hSpCas9	negative selection	3949771
21373405	21373428	12	-	26780180	HT29	viability (GeCKOv2 library)	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.828837567761143	[]	[]	3	hSpCas9	negative selection	4057732
21378270	21378293	12	+	26780180	HT29	viability (GeCKOv2 library)	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	1.02451053183872	[]	[]	5	hSpCas9	negative selection	4057733
21378353	21378376	12	+	26780180	HT29	viability (GeCKOv2 library)	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.529083564113634	[]	[]	1	hSpCas9	negative selection	4057734
21378304	21378327	12	+	26780180	HT29	viability (GeCKOv2 library)	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	1.26705538031165	[]	[]	6	hSpCas9	negative selection	4057735
21378403	21378426	12	-	26780180	HT29	viability (GeCKOv2 library)	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.355267433827179	[]	[]	1	hSpCas9	negative selection	4057736
21373410	21373433	12	+	26780180	HT29	viability (GeCKOv2 library)	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.587530524890379	[]	[]	2	hSpCas9	negative selection	4057737
21373421	21373444	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAAGTTACCAACCTTTCAATGGG	IAPP	ENSG00000121351	0.013332022681961805	[3]	[1,2]	0	hSpCas9	positive selection	4143786
21378270	21378293	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.15721084450938783	[3]	[1,1]	-4	hSpCas9	positive selection	4143787
21378329	21378352	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.37075495290719507	[2]	[2,2]	8	hSpCas9	positive selection	4143788
21373410	21373433	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.07026103290100845	[3]	[2,2]	1	hSpCas9	positive selection	4143789
21373421	21373444	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAAGTTACCAACCTTTCAATGGG	IAPP	ENSG00000121351	0.3621616895396274	[4]	[3,3,3,0]	2	hSpCas9	positive selection	4207808
21378270	21378293	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.4429512884928609	[4]	[1,0,2,0]	-6	hSpCas9	positive selection	4207809
21378329	21378352	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.0329825742130887	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4207810
21373410	21373433	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	-0.04338127348543168	[3]	[1,0,4,0]	0	hSpCas9	positive selection	4207811
21378270	21378293	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.8704440636095176	[1]	[2,2]	9	hSpCas9	positive selection	4276149
21378403	21378426	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.4393023589248599	[3]	[2,4]	8	hSpCas9	positive selection	4276150
21373410	21373433	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.3133527838375324	[2]	[2,2]	6	hSpCas9	positive selection	4276151
21373405	21373428	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.4407052564133128	[1]	[1,0]	8	hSpCas9	positive selection	4340407
21378304	21378327	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.49829556807187303	[3]	[3,3]	8	hSpCas9	positive selection	4340408
21378353	21378376	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.2906286461727399	[3]	[2,2]	6	hSpCas9	positive selection	4340409
21378226	21378248	12	+	27760321	OCIAML3	viability	CATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.19968156511898824	[407,376]	[265,268]	-2	hSpCas9	negative selection	4408563
21378271	21378293	12	+	27760321	OCIAML3	viability	ACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.0375198448254388	[635,517]	[380,510]	0	hSpCas9	negative selection	4408564
21378288	21378310	12	-	27760321	OCIAML3	viability	ATGAACTAAAAAATTTGCCAGG	IAPP	ENSG00000121351	0.24295082122441158	[143,110]	[94,145]	3	hSpCas9	negative selection	4408565
21378311	21378333	12	-	27760321	OCIAML3	viability	ATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	-0.4247812973185545	[603,558]	[284,408]	-4	hSpCas9	negative selection	4408566
21378332	21378354	12	+	27760321	OCIAML3	viability	TTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.5495344746014086	[376,354]	[328,536]	6	hSpCas9	negative selection	4408567
21378226	21378248	12	+	27760321	OCIAML2	viability	CATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.1411055754575088	[407,376]	[243,489]	1	hSpCas9	negative selection	4492026
21378271	21378293	12	+	27760321	OCIAML2	viability	ACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.23488985294444714	[635,517]	[473,641]	3	hSpCas9	negative selection	4492027
21378288	21378310	12	-	27760321	OCIAML2	viability	ATGAACTAAAAAATTTGCCAGG	IAPP	ENSG00000121351	-0.078267591431596	[143,110]	[99,92]	-1	hSpCas9	negative selection	4492028
21378311	21378333	12	-	27760321	OCIAML2	viability	ATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	0.2719478283723669	[603,558]	[476,687]	3	hSpCas9	negative selection	4492029
21378332	21378354	12	+	27760321	OCIAML2	viability	TTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	-0.25460796944975533	[376,354]	[275,211]	-3	hSpCas9	negative selection	4492030
21378226	21378248	12	+	27760321	MV411	viability	CATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.3267533678548896	[407,376]	[158,573]	2	hSpCas9	negative selection	4575489
21378271	21378293	12	+	27760321	MV411	viability	ACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	1.0313783595636064	[635,517]	[886,604]	7	hSpCas9	negative selection	4575490
21378288	21378310	12	-	27760321	MV411	viability	ATGAACTAAAAAATTTGCCAGG	IAPP	ENSG00000121351	-0.6297808115067052	[143,110]	[25,95]	-4	hSpCas9	negative selection	4575491
21378311	21378333	12	-	27760321	MV411	viability	ATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	0.6526317053462349	[603,558]	[729,412]	5	hSpCas9	negative selection	4575492
21378332	21378354	12	+	27760321	MV411	viability	TTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	-0.476127097324291	[376,354]	[142,219]	-3	hSpCas9	negative selection	4575493
21378226	21378248	12	+	27760321	HL60	viability	CATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.20388548909465543	[407,376]	[362,375]	2	hSpCas9	negative selection	4658952
21378271	21378293	12	+	27760321	HL60	viability	ACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.022375217034246553	[635,517]	[401,554]	0	hSpCas9	negative selection	4658953
21378288	21378310	12	-	27760321	HL60	viability	ATGAACTAAAAAATTTGCCAGG	IAPP	ENSG00000121351	-0.24260534169167292	[143,110]	[66,108]	-3	hSpCas9	negative selection	4658954
21378311	21378333	12	-	27760321	HL60	viability	ATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	0.29914381892457537	[603,558]	[601,565]	4	hSpCas9	negative selection	4658955
21378332	21378354	12	+	27760321	HL60	viability	TTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.30916416503081673	[376,354]	[394,344]	4	hSpCas9	negative selection	4658956
21378226	21378248	12	+	27760321	HT1080	viability	CATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	1.0952687712965719	[376,293]	[317,249]	6	hSpCas9	negative selection	4742415
21378271	21378293	12	+	27760321	HT1080	viability	ACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	1.4636992743393578	[517,403]	[727,263]	7	hSpCas9	negative selection	4742416
21378288	21378310	12	-	27760321	HT1080	viability	ATGAACTAAAAAATTTGCCAGG	IAPP	ENSG00000121351	-1.1950708125202871	[110,86]	[0,34]	-5	hSpCas9	negative selection	4742417
21378311	21378333	12	-	27760321	HT1080	viability	ATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	0.7713902086769208	[558,435]	[164,527]	4	hSpCas9	negative selection	4742418
21378332	21378354	12	+	27760321	HT1080	viability	TTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	-0.09658377888045677	[354,276]	[90,146]	0	hSpCas9	negative selection	4742419
21378226	21378248	12	+	27760321	HT29	viability after 7 days	CATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.28397882953868736	[376,293]	[639,421,528]	4	hSpCas9	negative selection	4825878
21378271	21378293	12	+	27760321	HT29	viability after 7 days	ACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.20480059482898316	[517,403]	[681,710,655]	3	hSpCas9	negative selection	4825879
21378288	21378310	12	-	27760321	HT29	viability after 7 days	ATGAACTAAAAAATTTGCCAGG	IAPP	ENSG00000121351	-0.0200146830188499	[110,86]	[82,115,169]	0	hSpCas9	negative selection	4825880
21378311	21378333	12	-	27760321	HT29	viability after 7 days	ATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	-0.16966847651550482	[558,435]	[638,597,480]	-2	hSpCas9	negative selection	4825881
21378332	21378354	12	+	27760321	HT29	viability after 7 days	TTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	-0.557837841428675	[354,276]	[310,290,231]	-7	hSpCas9	negative selection	4825882
21378226	21378248	12	+	27760321	HT29	viability after 25 days	CATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.4586812577380804	[376,293]	[552,422,610]	5	hSpCas9	negative selection	4909341
21378271	21378293	12	+	27760321	HT29	viability after 25 days	ACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.3581444180862513	[517,403]	[502,698,851]	4	hSpCas9	negative selection	4909342
21378288	21378310	12	-	27760321	HT29	viability after 25 days	ATGAACTAAAAAATTTGCCAGG	IAPP	ENSG00000121351	-0.15173942655004224	[110,86]	[109,83,111]	-1	hSpCas9	negative selection	4909343
21378311	21378333	12	-	27760321	HT29	viability after 25 days	ATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	-0.24250290613551306	[558,435]	[440,456,552]	-3	hSpCas9	negative selection	4909344
21378332	21378354	12	+	27760321	HT29	viability after 25 days	TTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	-0.1512740229684787	[354,276]	[446,206,311]	-1	hSpCas9	negative selection	4909345
21378226	21378248	12	+	27760321	HT29	viability after 22 days	CATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.6054844301463815	[376,293]	[859,515,384]	6	hSpCas9	negative selection	4992804
21378271	21378293	12	+	27760321	HT29	viability after 22 days	ACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.1521682181273919	[517,403]	[678,525,568]	1	hSpCas9	negative selection	4992805
21378288	21378310	12	-	27760321	HT29	viability after 22 days	ATGAACTAAAAAATTTGCCAGG	IAPP	ENSG00000121351	-0.5561554609396875	[110,86]	[66,74,91]	-5	hSpCas9	negative selection	4992806
21378311	21378333	12	-	27760321	HT29	viability after 22 days	ATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	-0.16679648466114444	[558,435]	[536,619,377]	-2	hSpCas9	negative selection	4992807
21378332	21378354	12	+	27760321	HT29	viability after 22 days	TTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	-0.33425134983288307	[354,276]	[419,233,210]	-3	hSpCas9	negative selection	4992808
21378226	21378248	12	+	27760321	HT29	viability after 19 days	CATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.3914325040015035	[376,293]	[1061,324,192]	4	hSpCas9	negative selection	5076267
21378271	21378293	12	+	27760321	HT29	viability after 19 days	ACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.7640841923051125	[517,403]	[873,987,823]	7	hSpCas9	negative selection	5076268
21378288	21378310	12	-	27760321	HT29	viability after 19 days	ATGAACTAAAAAATTTGCCAGG	IAPP	ENSG00000121351	0.028492765359308336	[110,86]	[146,200,5]	0	hSpCas9	negative selection	5076269
21378311	21378333	12	-	27760321	HT29	viability after 19 days	ATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	-0.5489491429044526	[558,435]	[420,231,511]	-5	hSpCas9	negative selection	5076270
21378332	21378354	12	+	27760321	HT29	viability after 19 days	TTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	-0.5949924253912889	[354,276]	[218,216,277]	-5	hSpCas9	negative selection	5076271
21378226	21378248	12	+	27760321	HT29	viability after 16 days	CATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.27481658418327976	[376,293]	[543,366,461]	3	hSpCas9	negative selection	5159730
21378271	21378293	12	+	27760321	HT29	viability after 16 days	ACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.4192465074698256	[517,403]	[530,762,757]	5	hSpCas9	negative selection	5159731
21378288	21378310	12	-	27760321	HT29	viability after 16 days	ATGAACTAAAAAATTTGCCAGG	IAPP	ENSG00000121351	0.36769591352921926	[110,86]	[78,134,208]	4	hSpCas9	negative selection	5159732
21378311	21378333	12	-	27760321	HT29	viability after 16 days	ATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	0.12515888939978193	[558,435]	[721,485,626]	1	hSpCas9	negative selection	5159733
21378332	21378354	12	+	27760321	HT29	viability after 16 days	TTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.005794375720872769	[354,276]	[391,328,347]	0	hSpCas9	negative selection	5159734
21378226	21378248	12	+	27760321	HT29	viability after 13 days	CATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.2140021549813843	[376,293]	[519,415,419]	2	hSpCas9	negative selection	5243193
21378271	21378293	12	+	27760321	HT29	viability after 13 days	ACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.029480754140773002	[517,403]	[568,551,454]	0	hSpCas9	negative selection	5243194
21378288	21378310	12	-	27760321	HT29	viability after 13 days	ATGAACTAAAAAATTTGCCAGG	IAPP	ENSG00000121351	0.10562752028211331	[110,86]	[107,124,136]	1	hSpCas9	negative selection	5243195
21378311	21378333	12	-	27760321	HT29	viability after 13 days	ATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	-0.029096479603220426	[558,435]	[928,339,434]	0	hSpCas9	negative selection	5243196
21378332	21378354	12	+	27760321	HT29	viability after 13 days	TTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	-0.09082468348387246	[354,276]	[442,272,317]	-1	hSpCas9	negative selection	5243197
21378226	21378248	12	+	27760321	HT29	viability after 10 days	CATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.28326102346218573	[376,293]	[473,522,531]	4	hSpCas9	negative selection	5326656
21378271	21378293	12	+	27760321	HT29	viability after 10 days	ACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.21121237480509525	[517,403]	[630,605,757]	2	hSpCas9	negative selection	5326657
21378288	21378310	12	-	27760321	HT29	viability after 10 days	ATGAACTAAAAAATTTGCCAGG	IAPP	ENSG00000121351	-0.8082449219126004	[110,86]	[122,70,18]	-7	hSpCas9	negative selection	5326658
21378311	21378333	12	-	27760321	HT29	viability after 10 days	ATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	0.5089373533754546	[558,435]	[880,514,1236]	7	hSpCas9	negative selection	5326659
21378332	21378354	12	+	27760321	HT29	viability after 10 days	TTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	-0.4326764111718677	[354,276]	[409,161,300]	-5	hSpCas9	negative selection	5326660
21378226	21378248	12	+	27760321	MOLM13	viability	CATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.6317475118209359	[407,376]	[300,378]	4	hSpCas9	negative selection	5410119
21378271	21378293	12	+	27760321	MOLM13	viability	ACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.17859990892672825	[635,517]	[404,184]	-1	hSpCas9	negative selection	5410120
21378288	21378310	12	-	27760321	MOLM13	viability	ATGAACTAAAAAATTTGCCAGG	IAPP	ENSG00000121351	0.3670500932124241	[143,110]	[110,75]	2	hSpCas9	negative selection	5410121
21378311	21378333	12	-	27760321	MOLM13	viability	ATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	1.637209297230054	[603,558]	[668,1319]	9	hSpCas9	negative selection	5410122
21378332	21378354	12	+	27760321	MOLM13	viability	TTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.9032645065387626	[376,354]	[513,277]	6	hSpCas9	negative selection	5410123
21372883	21372906	12	+	27661255	K562	viability	GGATTACTAGTTAGCAAATGAGG	IAPP	ENSG00000121351	0.07024228484267284	[650,775]	[643,555]	2	dCas9-KRAB	negative selection	5485966
21372983	21373006	12	+	27661255	K562	viability	GCTGACATTGAAACATTAAAAGG	IAPP	ENSG00000121351	0.24959908194985175	[590,582]	[677,454]	8	dCas9-KRAB	negative selection	5485967
21372917	21372940	12	-	27661255	K562	viability	GAGTCCAAGCTTGTATCCACTGG	IAPP	ENSG00000121351	0.06295083501858412	[352,367]	[312,289]	2	dCas9-KRAB	negative selection	5485968
21378270	21378293	12	+	27260156	BXPC3	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.009320717390663091	[102]	[104,79,79,177]	0	hSpCas9	negative selection	5548609
21378403	21378426	12	-	27260156	BXPC3	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.35293333748288935	[708]	[915,778,1002,1117]	7	hSpCas9	negative selection	5548610
21373410	21373433	12	+	27260156	BXPC3	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.22812097754665084	[279]	[386,362,258,353]	5	hSpCas9	negative selection	5548611
21373405	21373428	12	-	27260156	BXPC3	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.14876949549462282	[69]	[82,36,94,115]	3	hSpCas9	negative selection	5612867
21378304	21378327	12	+	27260156	BXPC3	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.49016044117021923	[477]	[594,593,821,827]	9	hSpCas9	negative selection	5612868
21378353	21378376	12	+	27260156	BXPC3	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.19036338867749952	[486]	[402,451,418,520]	-4	hSpCas9	negative selection	5612869
21378270	21378293	12	+	27260156	A673	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.024443332776719284	[102]	[184,81,129,95]	0	hSpCas9	negative selection	5669860
21378403	21378426	12	-	27260156	A673	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.2972448702531514	[708]	[1088,936,1152,1007]	7	hSpCas9	negative selection	5669861
21373410	21373433	12	+	27260156	A673	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.10385473332064976	[279]	[412,297,363,377]	2	hSpCas9	negative selection	5669862
21373405	21373428	12	-	27260156	A673	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.3619206976017373	[69]	[52,100,44,59]	-7	hSpCas9	negative selection	5734118
21378304	21378327	12	+	27260156	A673	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.48559311689681944	[477]	[928,725,882,683]	9	hSpCas9	negative selection	5734119
21378353	21378376	12	+	27260156	A673	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.12364430720144978	[486]	[650,509,482,514]	-3	hSpCas9	negative selection	5734120
21378270	21378293	12	+	27260156	A375	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.14988177840689465	[102]	[185,246,51,71]	2	hSpCas9	negative selection	5791111
21378403	21378426	12	-	27260156	A375	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.4294768001491115	[708]	[984,1312,1363,852]	6	hSpCas9	negative selection	5791112
21373410	21373433	12	+	27260156	A375	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.2455646303670036	[279]	[283,432,487,353]	3	hSpCas9	negative selection	5791113
21373405	21373428	12	-	27260156	A375	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.19592204713459038	[69]	[65,15,174,25]	-3	hSpCas9	negative selection	5855369
21378304	21378327	12	+	27260156	A375	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.25922040288943893	[477]	[724,806,841,353]	4	hSpCas9	negative selection	5855370
21378353	21378376	12	+	27260156	A375	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.2270198987498281	[486]	[381,724,468,407]	-3	hSpCas9	negative selection	5855371
21378270	21378293	12	+	27260156	COLO741	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.2521269889361635	[102]	[206,137,130]	5	hSpCas9	negative selection	5912362
21378403	21378426	12	-	27260156	COLO741	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.3701280790419811	[708]	[1246,1053,1211]	7	hSpCas9	negative selection	5912363
21373410	21373433	12	+	27260156	COLO741	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.5112614020923689	[279]	[670,417,456]	8	hSpCas9	negative selection	5912364
21373405	21373428	12	-	27260156	COLO741	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.16234674664184112	[69]	[78,100,116]	3	hSpCas9	negative selection	5976620
21378304	21378327	12	+	27260156	COLO741	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.288864701412679	[477]	[726,773,734]	6	hSpCas9	negative selection	5976621
21378353	21378376	12	+	27260156	COLO741	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.08699556985715697	[486]	[980,452,579]	1	hSpCas9	negative selection	5976622
21378270	21378293	12	+	27260156	CAL120	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.6280232142300735	[102]	[177,206,205]	8	hSpCas9	negative selection	6033613
21378403	21378426	12	-	27260156	CAL120	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.3129278966020794	[708]	[1119,901,1265]	5	hSpCas9	negative selection	6033614
21373410	21373433	12	+	27260156	CAL120	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.30966844151282197	[279]	[262,576,429]	4	hSpCas9	negative selection	6033615
21373405	21373428	12	-	27260156	CAL120	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.707581371327973	[69]	[36,92,27]	-7	hSpCas9	negative selection	6097871
21378304	21378327	12	+	27260156	CAL120	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.6367891706573199	[477]	[1301,886,646]	8	hSpCas9	negative selection	6097872
21378353	21378376	12	+	27260156	CAL120	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.05754857387943732	[486]	[490,716,525]	-1	hSpCas9	negative selection	6097873
21378270	21378293	12	+	27260156	CADOES1	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.036078405698612315	[102]	[107,95,137,48]	0	hSpCas9	negative selection	6154864
21378403	21378426	12	-	27260156	CADOES1	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.45772878290612107	[708]	[897,902,902,918]	7	hSpCas9	negative selection	6154865
21373410	21373433	12	+	27260156	CADOES1	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.3664555935838276	[279]	[413,298,258,371]	6	hSpCas9	negative selection	6154866
21373405	21373428	12	-	27260156	CADOES1	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.30264165507595786	[69]	[33,52,75,47]	-5	hSpCas9	negative selection	6219122
21378304	21378327	12	+	27260156	CADOES1	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.5354946720621218	[477]	[667,656,670,578]	8	hSpCas9	negative selection	6219123
21378353	21378376	12	+	27260156	CADOES1	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.1106785715385147	[486]	[583,493,490,382]	2	hSpCas9	negative selection	6219124
21378270	21378293	12	+	27260156	EWS502	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.08022169291125758	[102]	[81,87,176,66]	-1	hSpCas9	negative selection	6276115
21378403	21378426	12	-	27260156	EWS502	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.2414119816068614	[708]	[951,661,730,1225]	4	hSpCas9	negative selection	6276116
21373410	21373433	12	+	27260156	EWS502	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.03650079709703469	[279]	[290,252,405,267]	0	hSpCas9	negative selection	6276117
21373405	21373428	12	-	27260156	EWS502	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.04155839830593777	[69]	[61,32,190,19]	0	hSpCas9	negative selection	6340373
21378304	21378327	12	+	27260156	EWS502	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.44859213274373755	[477]	[563,584,916,719]	7	hSpCas9	negative selection	6340374
21378353	21378376	12	+	27260156	EWS502	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.012262288041717667	[486]	[398,360,619,736]	0	hSpCas9	negative selection	6340375
21378270	21378293	12	+	27260156	EW8	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.020917595113962406	[102]	[104,87,90,45]	0	hSpCas9	negative selection	6397366
21378403	21378426	12	-	27260156	EW8	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.18361428621249787	[708]	[815,662,519,649]	3	hSpCas9	negative selection	6397367
21373410	21373433	12	+	27260156	EW8	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	-0.01966934943728571	[279]	[263,215,134,298]	0	hSpCas9	negative selection	6397368
21373405	21373428	12	-	27260156	EW8	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.6658114748584216	[69]	[14,29,68,20]	-8	hSpCas9	negative selection	6461624
21378304	21378327	12	+	27260156	EW8	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.2772175377984881	[477]	[454,336,527,543]	5	hSpCas9	negative selection	6461625
21378353	21378376	12	+	27260156	EW8	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.0626984365456284	[486]	[366,373,252,535]	-1	hSpCas9	negative selection	6461626
21378270	21378293	12	+	27260156	CORL105	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.24977783399967168	[102]	[259,113,140,62]	4	hSpCas9	negative selection	6518617
21378403	21378426	12	-	27260156	CORL105	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.5364558791044766	[708]	[1011,1236,1421,1170]	8	hSpCas9	negative selection	6518618
21373410	21373433	12	+	27260156	CORL105	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.525838979153968	[279]	[425,399,765,341]	8	hSpCas9	negative selection	6518619
21373405	21373428	12	-	27260156	CORL105	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.23743478615051883	[69]	[150,64,102,70]	4	hSpCas9	negative selection	6582875
21378304	21378327	12	+	27260156	CORL105	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.5012711863471362	[477]	[691,689,1049,774]	8	hSpCas9	negative selection	6582876
21378353	21378376	12	+	27260156	CORL105	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.12582566944906748	[486]	[482,552,535,517]	-2	hSpCas9	negative selection	6582877
21378270	21378293	12	+	27260156	HS294T	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.470792593810774	[102]	[38,29,78,78]	6	hSpCas9	negative selection	6639868
21378403	21378426	12	-	27260156	HS294T	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.2962146050050719	[708]	[342,416,294,276]	4	hSpCas9	negative selection	6639869
21373410	21373433	12	+	27260156	HS294T	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	-0.12482030423411028	[279]	[39,187,79,89]	-2	hSpCas9	negative selection	6639870
21373405	21373428	12	-	27260156	HS294T	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	1.0926113280429453	[69]	[18,57,36,132]	9	hSpCas9	negative selection	6704126
21378304	21378327	12	+	27260156	HS294T	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.5218239915548801	[477]	[210,258,215,402]	7	hSpCas9	negative selection	6704127
21378353	21378376	12	+	27260156	HS294T	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.4036567053331174	[486]	[97,175,155,141]	-5	hSpCas9	negative selection	6704128
21378270	21378293	12	+	27260156	HCC44	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.14067858123328358	[102]	[139,44,198,66]	-2	hSpCas9	negative selection	6761119
21378403	21378426	12	-	27260156	HCC44	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.20401243841649386	[708]	[987,734,1068,951]	3	hSpCas9	negative selection	6761120
21373410	21373433	12	+	27260156	HCC44	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.20012731879218304	[279]	[323,316,461,368]	3	hSpCas9	negative selection	6761121
21373405	21373428	12	-	27260156	HCC44	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.1854078793311964	[69]	[42,30,180,45]	-3	hSpCas9	negative selection	6825377
21378304	21378327	12	+	27260156	HCC44	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.6042763947741546	[477]	[792,618,837,1051]	8	hSpCas9	negative selection	6825378
21378353	21378376	12	+	27260156	HCC44	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.0008107036431391351	[486]	[924,366,587,391]	0	hSpCas9	negative selection	6825379
21378270	21378293	12	+	27260156	G402	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.162213861983437	[102]	[62,246,15,122]	-2	hSpCas9	negative selection	6882370
21378403	21378426	12	-	27260156	G402	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.2307831035337058	[708]	[876,769,1452,926]	3	hSpCas9	negative selection	6882371
21373410	21373433	12	+	27260156	G402	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.16320758987627382	[279]	[421,292,297,509]	2	hSpCas9	negative selection	6882372
21373405	21373428	12	-	27260156	G402	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.28030456235388534	[69]	[118,91,21,56]	-4	hSpCas9	negative selection	6946628
21378304	21378327	12	+	27260156	G402	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.43437528791028535	[477]	[842,1261,459,627]	5	hSpCas9	negative selection	6946629
21378353	21378376	12	+	27260156	G402	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.0037556203795513013	[486]	[805,288,694,602]	0	hSpCas9	negative selection	6946630
21378270	21378293	12	+	27260156	L33	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.08280359204471432	[102]	[69,36,60,131]	-2	hSpCas9	negative selection	7003621
21378403	21378426	12	-	27260156	L33	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.3123315494615827	[708]	[910,347,581,834]	6	hSpCas9	negative selection	7003622
21373410	21373433	12	+	27260156	L33	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	-0.02832444322598726	[279]	[292,103,189,248]	0	hSpCas9	negative selection	7003623
21373405	21373428	12	-	27260156	L33	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.9003960985882191	[69]	[131,65,108,56]	9	hSpCas9	negative selection	7067879
21378304	21378327	12	+	27260156	L33	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.26870170058568665	[477]	[524,243,403,541]	6	hSpCas9	negative selection	7067880
21378353	21378376	12	+	27260156	L33	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.2619991963399722	[486]	[529,177,206,327]	-6	hSpCas9	negative selection	7067881
21378270	21378293	12	+	27260156	K562	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.7030313879974224	[102]	[69,11,73,65]	-7	hSpCas9	negative selection	7124872
21378403	21378426	12	-	27260156	K562	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.15325340406284904	[708]	[896,901,506,535]	2	hSpCas9	negative selection	7124873
21373410	21373433	12	+	27260156	K562	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.0893582965315457	[279]	[190,237,346,271]	1	hSpCas9	negative selection	7124874
21373405	21373428	12	-	27260156	K562	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.23836654509516952	[69]	[54,28,40,80]	-3	hSpCas9	negative selection	7189130
21378304	21378327	12	+	27260156	K562	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.5534478524806574	[477]	[263,472,1238,489]	7	hSpCas9	negative selection	7189131
21378353	21378376	12	+	27260156	K562	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.40491298653565494	[486]	[353,364,389,212]	-5	hSpCas9	negative selection	7189132
21378270	21378293	12	+	27260156	HT29	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.5141479960757507	[102]	[121,98,74,60]	-7	hSpCas9	negative selection	7246123
21378403	21378426	12	-	27260156	HT29	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.2763483479686517	[708]	[964,847,1118,1193]	5	hSpCas9	negative selection	7246124
21373410	21373433	12	+	27260156	HT29	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.15825780895235786	[279]	[481,412,303,333]	3	hSpCas9	negative selection	7246125
21373405	21373428	12	-	27260156	HT29	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.010171320716482857	[69]	[170,49,70,52]	0	hSpCas9	negative selection	7310381
21378304	21378327	12	+	27260156	HT29	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.44824529237775146	[477]	[743,857,922,658]	8	hSpCas9	negative selection	7310382
21378353	21378376	12	+	27260156	HT29	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.11483856432551202	[486]	[612,627,452,505]	-2	hSpCas9	negative selection	7310383
21378270	21378293	12	+	27260156	MHHES1	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.246029306462606	[102]	[146,42,134,70]	-5	hSpCas9	negative selection	7367374
21378403	21378426	12	-	27260156	MHHES1	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.2859174859475053	[708]	[1382,864,989,729]	5	hSpCas9	negative selection	7367375
21373410	21373433	12	+	27260156	MHHES1	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.3190532675238504	[279]	[508,446,451,217]	6	hSpCas9	negative selection	7367376
21373405	21373428	12	-	27260156	MHHES1	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.2874481912713964	[69]	[68,79,40,67]	-5	hSpCas9	negative selection	7431632
21378304	21378327	12	+	27260156	MHHES1	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.561690962486358	[477]	[864,848,982,538]	8	hSpCas9	negative selection	7431633
21378353	21378376	12	+	27260156	MHHES1	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.16285654232807278	[486]	[598,615,364,411]	-3	hSpCas9	negative selection	7431634
21378270	21378293	12	+	27260156	MEWO	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.555956053489508	[102]	[57,98,37]	-8	hSpCas9	negative selection	7488625
21378403	21378426	12	-	27260156	MEWO	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.13274316842600353	[708]	[933,648,638]	3	hSpCas9	negative selection	7488626
21373410	21373433	12	+	27260156	MEWO	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.1484044133504705	[279]	[366,249,268]	3	hSpCas9	negative selection	7488627
21373405	21373428	12	-	27260156	MEWO	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.2398386880443275	[69]	[68,52,46]	-5	hSpCas9	negative selection	7552883
21378304	21378327	12	+	27260156	MEWO	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.3075375095730148	[477]	[732,555,405]	6	hSpCas9	negative selection	7552884
21378353	21378376	12	+	27260156	MEWO	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.3123619932067758	[486]	[500,295,329]	-6	hSpCas9	negative selection	7552885
21378270	21378293	12	+	27260156	LNCAPCLONEFGC	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.20102338799468122	[102]	[79,53,140,162]	3	hSpCas9	negative selection	7609876
21378403	21378426	12	-	27260156	LNCAPCLONEFGC	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.21071491178535828	[708]	[598,914,810,648]	3	hSpCas9	negative selection	7609877
21373410	21373433	12	+	27260156	LNCAPCLONEFGC	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.27480547266219163	[279]	[241,320,356,314]	4	hSpCas9	negative selection	7609878
21373405	21373428	12	-	27260156	LNCAPCLONEFGC	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.39526206226057736	[69]	[20,66,33,67]	-6	hSpCas9	negative selection	7674134
21378304	21378327	12	+	27260156	LNCAPCLONEFGC	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.6379661265134052	[477]	[640,516,917,665]	8	hSpCas9	negative selection	7674135
21378353	21378376	12	+	27260156	LNCAPCLONEFGC	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.017704036599516193	[486]	[418,415,421,527]	0	hSpCas9	negative selection	7674136
21378270	21378293	12	+	27260156	PANC0327	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.4637841945567418	[102]	[94,94,68,246]	6	hSpCas9	negative selection	7731127
21378403	21378426	12	-	27260156	PANC0327	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.29974601813187585	[708]	[728,812,730,818]	4	hSpCas9	negative selection	7731128
21373410	21373433	12	+	27260156	PANC0327	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.06973832895727217	[279]	[172,264,125,471]	1	hSpCas9	negative selection	7731129
21373405	21373428	12	-	27260156	PANC0327	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.48078106534482457	[69]	[40,157,23,110]	7	hSpCas9	negative selection	7795385
21378304	21378327	12	+	27260156	PANC0327	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.06739429328738045	[477]	[688,270,436,424]	1	hSpCas9	negative selection	7795386
21378353	21378376	12	+	27260156	PANC0327	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.49504829722344607	[486]	[511,721,551,629]	7	hSpCas9	negative selection	7795387
21378270	21378293	12	+	27260156	NCIH2009	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	1.1804166675548105	[102]	[175,448,320]	9	hSpCas9	negative selection	7852378
21378403	21378426	12	-	27260156	NCIH2009	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.033731656709827806	[708]	[1293,995,805]	0	hSpCas9	negative selection	7852379
21373410	21373433	12	+	27260156	NCIH2009	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.1657280566477718	[279]	[305,354,629]	2	hSpCas9	negative selection	7852380
21373405	21373428	12	-	27260156	NCIH2009	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.22786985796656145	[69]	[62,181,86]	3	hSpCas9	negative selection	7916636
21378304	21378327	12	+	27260156	NCIH2009	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.4658040033592081	[477]	[815,781,1148]	6	hSpCas9	negative selection	7916637
21378353	21378376	12	+	27260156	NCIH2009	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.3823194341308285	[486]	[574,501,498]	-5	hSpCas9	negative selection	7916638
21378270	21378293	12	+	27260156	NCIH1373	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.113722819037549	[102]	[46,51,179,37]	-1	hSpCas9	negative selection	7973629
21378403	21378426	12	-	27260156	NCIH1373	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	-0.43436414581906163	[708]	[622,269,969,134]	-4	hSpCas9	negative selection	7973630
21373410	21373433	12	+	27260156	NCIH1373	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.4371085315705707	[279]	[281,510,340,141]	4	hSpCas9	negative selection	7973631
21373405	21373428	12	-	27260156	NCIH1373	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	1.2234122841867807	[69]	[402,99,115,40]	9	hSpCas9	negative selection	8037887
21378304	21378327	12	+	27260156	NCIH1373	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.3370229312569394	[477]	[707,566,618,219]	3	hSpCas9	negative selection	8037888
21378353	21378376	12	+	27260156	NCIH1373	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.9839109802797504	[486]	[253,194,364,76]	-7	hSpCas9	negative selection	8037889
21378270	21378293	12	+	27260156	PATU8902	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.44892681569815474	[102]	[508,41,145,78]	4	hSpCas9	negative selection	8094880
21378403	21378426	12	-	27260156	PATU8902	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	-0.04495975485860504	[708]	[914,777,1118,967]	0	hSpCas9	negative selection	8094881
21373410	21373433	12	+	27260156	PATU8902	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.3760700758286477	[279]	[644,465,533,346]	4	hSpCas9	negative selection	8094882
21373405	21373428	12	-	27260156	PATU8902	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-1.349103696231054	[69]	[46,17,5,96]	-8	hSpCas9	negative selection	8159138
21378304	21378327	12	+	27260156	PATU8902	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	-0.27334928865994	[477]	[286,406,856,573]	-3	hSpCas9	negative selection	8159139
21378353	21378376	12	+	27260156	PATU8902	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.3419484368074151	[486]	[438,684,268,851]	-3	hSpCas9	negative selection	8159140
21378270	21378293	12	+	27260156	PANC1	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.35473243123426856	[102]	[153,252,41,40]	6	hSpCas9	negative selection	8216131
21378403	21378426	12	-	27260156	PANC1	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.4440810930230005	[708]	[1064,981,724,592]	7	hSpCas9	negative selection	8216132
21373410	21373433	12	+	27260156	PANC1	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.3952119420305138	[279]	[279,329,458,212]	6	hSpCas9	negative selection	8216133
21373405	21373428	12	-	27260156	PANC1	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.01951026068755013	[69]	[34,85,49,74]	0	hSpCas9	negative selection	8280389
21378304	21378327	12	+	27260156	PANC1	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.2710304470592868	[477]	[494,668,521,347]	4	hSpCas9	negative selection	8280390
21378353	21378376	12	+	27260156	PANC1	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.25449843783120185	[486]	[396,408,396,225]	-4	hSpCas9	negative selection	8280391
21378270	21378293	12	+	27260156	PANC0813	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.40766702993824877	[102]	[104,111,257,161]	6	hSpCas9	negative selection	8337382
21378403	21378426	12	-	27260156	PANC0813	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.6815490299794674	[708]	[1118,1498,1354,1346]	9	hSpCas9	negative selection	8337383
21373410	21373433	12	+	27260156	PANC0813	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.19535238136266875	[279]	[437,368,272,427]	3	hSpCas9	negative selection	8337384
21373405	21373428	12	-	27260156	PANC0813	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.8775698916674102	[69]	[116,128,252,104]	9	hSpCas9	negative selection	8401640
21378304	21378327	12	+	27260156	PANC0813	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.3627808854010195	[477]	[597,629,867,776]	6	hSpCas9	negative selection	8401641
21378353	21378376	12	+	27260156	PANC0813	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.009749979724373171	[486]	[463,494,803,532]	0	hSpCas9	negative selection	8401642
21378270	21378293	12	+	27260156	RDES	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.09545896517196839	[102]	[114,60,96,180]	-1	hSpCas9	negative selection	8458633
21378403	21378426	12	-	27260156	RDES	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	-0.07219730462167151	[708]	[507,807,908,940]	-1	hSpCas9	negative selection	8458634
21373410	21373433	12	+	27260156	RDES	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.16601392311053098	[279]	[367,339,276,459]	2	hSpCas9	negative selection	8458635
21373405	21373428	12	-	27260156	RDES	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.2962619785477578	[69]	[53,57,95,54]	-5	hSpCas9	negative selection	8522891
21378304	21378327	12	+	27260156	RDES	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.45532712026068745	[477]	[559,735,831,939]	7	hSpCas9	negative selection	8522892
21378353	21378376	12	+	27260156	RDES	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.20584748684440224	[486]	[348,552,463,601]	-3	hSpCas9	negative selection	8522893
21378270	21378293	12	+	27260156	PC3	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.22643935330675458	[102]	[48,62,188,100]	-5	hSpCas9	negative selection	8579884
21378403	21378426	12	-	27260156	PC3	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.25250803791846554	[708]	[456,994,1456,781]	5	hSpCas9	negative selection	8579885
21373410	21373433	12	+	27260156	PC3	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.33376294869617495	[279]	[166,207,964,370]	7	hSpCas9	negative selection	8579886
21373405	21373428	12	-	27260156	PC3	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.6348582021276536	[69]	[48,43,324,122]	9	hSpCas9	negative selection	8644142
21378304	21378327	12	+	27260156	PC3	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.5813138597254421	[477]	[397,799,1249,680]	9	hSpCas9	negative selection	8644143
21378353	21378376	12	+	27260156	PC3	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.0029073840535290135	[486]	[325,459,697,568]	0	hSpCas9	negative selection	8644144
21378270	21378293	12	+	27260156	PATU8988T	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.05183158840784019	[102]	[192,114,24,79]	0	hSpCas9	negative selection	8701135
21378403	21378426	12	-	27260156	PATU8988T	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.3955782484443947	[708]	[1058,838,960,724]	6	hSpCas9	negative selection	8701136
21373410	21373433	12	+	27260156	PATU8988T	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.46058194978237593	[279]	[283,484,494,221]	7	hSpCas9	negative selection	8701137
21373405	21373428	12	-	27260156	PATU8988T	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.25885656078543784	[69]	[121,22,34,143]	4	hSpCas9	negative selection	8765393
21378304	21378327	12	+	27260156	PATU8988T	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.36962233501256625	[477]	[438,656,582,723]	6	hSpCas9	negative selection	8765394
21378353	21378376	12	+	27260156	PATU8988T	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.07930115421583812	[486]	[507,848,201,463]	1	hSpCas9	negative selection	8765395
21378270	21378293	12	+	27260156	T47D	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.32810974476614474	[102]	[109,83,101,86]	-6	hSpCas9	negative selection	8822386
21378403	21378426	12	-	27260156	T47D	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.1455027338878061	[708]	[889,891,862,1014]	3	hSpCas9	negative selection	8822387
21373410	21373433	12	+	27260156	T47D	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.10898725720632407	[279]	[385,339,341,339]	2	hSpCas9	negative selection	8822388
21373405	21373428	12	-	27260156	T47D	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.2111163306730428	[69]	[93,46,122,117]	4	hSpCas9	negative selection	8886644
21378304	21378327	12	+	27260156	T47D	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.4811250288327465	[477]	[850,662,793,811]	8	hSpCas9	negative selection	8886645
21378353	21378376	12	+	27260156	T47D	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.05001694120688681	[486]	[584,475,520,618]	-1	hSpCas9	negative selection	8886646
21378270	21378293	12	+	27260156	SU8686	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.46753009036891946	[102]	[161,78,118,221]	7	hSpCas9	negative selection	8943637
21378403	21378426	12	-	27260156	SU8686	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.46066073598424506	[708]	[812,874,886,1381]	7	hSpCas9	negative selection	8943638
21373410	21373433	12	+	27260156	SU8686	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.18807521573144093	[279]	[279,282,426,277]	3	hSpCas9	negative selection	8943639
21373405	21373428	12	-	27260156	SU8686	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.2319236022672726	[69]	[80,89,71,80]	4	hSpCas9	negative selection	9007895
21378304	21378327	12	+	27260156	SU8686	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.3697912282490727	[477]	[636,574,511,740]	6	hSpCas9	negative selection	9007896
21378353	21378376	12	+	27260156	SU8686	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.7353892206064551	[486]	[218,239,354,373]	-8	hSpCas9	negative selection	9007897
21378270	21378293	12	+	27260156	SKES1	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.32139493903089966	[102]	[192,110,132,86]	6	hSpCas9	negative selection	9064888
21378403	21378426	12	-	27260156	SKES1	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.2368854553823735	[708]	[852,860,756,857]	5	hSpCas9	negative selection	9064889
21373410	21373433	12	+	27260156	SKES1	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.3712763406959322	[279]	[362,518,245,336]	7	hSpCas9	negative selection	9064890
21373405	21373428	12	-	27260156	SKES1	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.03259728910677406	[69]	[84,100,22,69]	0	hSpCas9	negative selection	9129146
21378304	21378327	12	+	27260156	SKES1	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.5635375933057413	[477]	[728,766,661,668]	9	hSpCas9	negative selection	9129147
21378353	21378376	12	+	27260156	SKES1	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.09198216590014117	[486]	[585,516,560,421]	2	hSpCas9	negative selection	9129148
21378270	21378293	12	+	27260156	TOV112D	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.19958903201954303	[102]	[176,189,75,54]	4	hSpCas9	negative selection	9186139
21378403	21378426	12	-	27260156	TOV112D	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.3847362443211175	[708]	[942,975,1007,796]	7	hSpCas9	negative selection	9186140
21373410	21373433	12	+	27260156	TOV112D	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.46116029120776286	[279]	[517,461,337,258]	8	hSpCas9	negative selection	9186141
21373405	21373428	12	-	27260156	TOV112D	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.33335654923689884	[69]	[36,101,152,60]	6	hSpCas9	negative selection	9250397
21378304	21378327	12	+	27260156	TOV112D	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.4094627042089679	[477]	[814,716,574,474]	7	hSpCas9	negative selection	9250398
21378353	21378376	12	+	27260156	TOV112D	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.17466937700555507	[486]	[531,499,435,288]	-3	hSpCas9	negative selection	9250399
21378270	21378293	12	+	27260156	TC71	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.16579531339862497	[102]	[97,140,99,159]	4	hSpCas9	negative selection	9307390
21378403	21378426	12	-	27260156	TC71	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.11832532993335454	[708]	[803,942,684,875]	3	hSpCas9	negative selection	9307391
21373410	21373433	12	+	27260156	TC71	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.2526801574797999	[279]	[337,310,388,393]	6	hSpCas9	negative selection	9307392
21373405	21373428	12	-	27260156	TC71	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	-0.285701075190111	[69]	[92,43,76,28]	-6	hSpCas9	negative selection	9371648
21378304	21378327	12	+	27260156	TC71	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.44591179316795515	[477]	[724,621,760,679]	8	hSpCas9	negative selection	9371649
21378353	21378376	12	+	27260156	TC71	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.14725265970062043	[486]	[391,449,500,547]	-4	hSpCas9	negative selection	9371650
21378270	21378293	12	+	27260156	TC32	viability	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.07286146560855311	[102]	[101,81,80,141]	1	hSpCas9	negative selection	9428641
21378403	21378426	12	-	27260156	TC32	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.27659062195184536	[708]	[754,661,962,891]	5	hSpCas9	negative selection	9428642
21373410	21373433	12	+	27260156	TC32	viability	TGAAAGCTACACCCATTGAAAGG	IAPP	ENSG00000121351	0.029538208752958317	[279]	[397,88,342,294]	0	hSpCas9	negative selection	9428643
21373405	21373428	12	-	27260156	TC32	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.07407306327650254	[69]	[77,0,120,109]	1	hSpCas9	negative selection	9492899
21378304	21378327	12	+	27260156	TC32	viability	GTTCATTCCAGCAACAACTTTGG	IAPP	ENSG00000121351	0.25769260024746643	[477]	[525,287,714,726]	4	hSpCas9	negative selection	9492900
21378353	21378376	12	+	27260156	TC32	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.11507613585479116	[486]	[396,257,551,554]	-2	hSpCas9	negative selection	9492901
21378225	21378248	12	+	27869803	HPAFII	viability after 27 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.16786434187593946	[310]	[258,50,NaN]	-1	hSpCas9	negative selection	9546286
21378270	21378293	12	+	27869803	HPAFII	viability after 27 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.609219719649911	[157]	[78,33,NaN]	-4	hSpCas9	negative selection	9546287
21378329	21378352	12	-	27869803	HPAFII	viability after 27 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.299833087157751	[335]	[289,156,NaN]	2	hSpCas9	negative selection	9546288
21378225	21378248	12	+	27869803	HPAFII	viability after 15 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.057529661903042706	[310]	[581,158,NaN]	0	hSpCas9	negative selection	9628735
21378270	21378293	12	+	27869803	HPAFII	viability after 15 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.4510735996756108	[157]	[93,142,NaN]	-5	hSpCas9	negative selection	9628736
21378329	21378352	12	-	27869803	HPAFII	viability after 15 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	-0.23896217390155303	[335]	[350,277,NaN]	-3	hSpCas9	negative selection	9628737
21378225	21378248	12	+	27869803	ASPC1	viability after 36 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.6966255478055821	[896]	[235,176,173]	-6	hSpCas9	negative selection	9711184
21378270	21378293	12	+	27869803	ASPC1	viability after 36 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-1.2574309373947632	[523]	[46,105,72]	-8	hSpCas9	negative selection	9711185
21378329	21378352	12	-	27869803	ASPC1	viability after 36 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.16861769980687663	[706]	[261,506,102]	1	hSpCas9	negative selection	9711186
21378225	21378248	12	+	27869803	PATU8988S	viability after 35 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.10207446523835273	[688]	[275,240,NaN]	-1	hSpCas9	negative selection	9793633
21378270	21378293	12	+	27869803	PATU8988S	viability after 35 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.031512227406864546	[392]	[93,215,NaN]	0	hSpCas9	negative selection	9793634
21378329	21378352	12	-	27869803	PATU8988S	viability after 35 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.3978150035511495	[569]	[283,320,NaN]	4	hSpCas9	negative selection	9793635
21378225	21378248	12	+	27869803	PATU8988S	viability after 31 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.18407533337386217	[688]	[323,296,NaN]	2	hSpCas9	negative selection	9876082
21378270	21378293	12	+	27869803	PATU8988S	viability after 31 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	0.07081078704316013	[392]	[113,228,NaN]	0	hSpCas9	negative selection	9876083
21378329	21378352	12	-	27869803	PATU8988S	viability after 31 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.18734541764404983	[569]	[260,255,NaN]	2	hSpCas9	negative selection	9876084
21378225	21378248	12	+	27869803	HPAFII	viability after 35 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.2624325752246296	[310]	[174,81,NaN]	-2	hSpCas9	negative selection	9958531
21378270	21378293	12	+	27869803	HPAFII	viability after 35 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.613378439683623	[157]	[32,73,NaN]	-4	hSpCas9	negative selection	9958532
21378329	21378352	12	-	27869803	HPAFII	viability after 35 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.43907423427348974	[335]	[271,183,NaN]	3	hSpCas9	negative selection	9958533
21378225	21378248	12	+	27869803	HPAFII	viability after 31 days	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.4258246648614625	[310]	[172,82,NaN]	-3	hSpCas9	negative selection	10040980
21378270	21378293	12	+	27869803	HPAFII	viability after 31 days	CACATGTGCAACGCAGCGCCTGG	IAPP	ENSG00000121351	-0.6507778561346524	[157]	[55,56,NaN]	-4	hSpCas9	negative selection	10040981
21378329	21378352	12	-	27869803	HPAFII	viability after 31 days	CACGTTGGTAGATGAGAGAATGG	IAPP	ENSG00000121351	0.716047517304292	[335]	[415,193,NaN]	5	hSpCas9	negative selection	10040982
21373405	21373428	12	-	28162770	P31FUJ	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.9702352842772667	[267]	[616]	9	hSpCas9	negative selection	10172288
21378311	21378334	12	-	28162770	P31FUJ	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	1.1809183663924743	[136]	[364]	9	hSpCas9	negative selection	10172289
21378403	21378426	12	-	28162770	P31FUJ	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.7274715172700107	[404]	[787]	8	hSpCas9	negative selection	10172290
21378225	21378248	12	+	28162770	P31FUJ	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.4961260706864091	[215]	[357]	5	hSpCas9	negative selection	10172291
21378233	21378256	12	+	28162770	P31FUJ	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.8738579035699173	[201]	[434]	8	hSpCas9	negative selection	10172292
21378344	21378367	12	-	28162770	P31FUJ	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	0.9847038615620437	[168]	[392]	9	hSpCas9	negative selection	10172293
21378353	21378376	12	+	28162770	P31FUJ	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.23961751700043454	[381]	[529]	2	hSpCas9	negative selection	10172294
21378269	21378292	12	-	28162770	P31FUJ	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	0.6088171323698548	[528]	[947]	7	hSpCas9	negative selection	10172295
21378331	21378354	12	+	28162770	P31FUJ	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.22069817017099713	[841]	[1152]	2	hSpCas9	negative selection	10172296
21378366	21378389	12	+	28162770	P31FUJ	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.5729610363788273	[437]	[345]	-5	hSpCas9	negative selection	10172297
21373405	21373428	12	-	28162770	TF1	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	NaN	[NaN]	[327]	1	hSpCas9	negative selection	10341654
21378311	21378334	12	-	28162770	TF1	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10341655
21378403	21378426	12	-	28162770	TF1	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	NaN	[NaN]	[287]	1	hSpCas9	negative selection	10341656
21378225	21378248	12	+	28162770	TF1	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	NaN	[NaN]	[205]	1	hSpCas9	negative selection	10341657
21378233	21378256	12	+	28162770	TF1	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	NaN	[NaN]	[194]	1	hSpCas9	negative selection	10341658
21378344	21378367	12	-	28162770	TF1	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	NaN	[NaN]	[179]	1	hSpCas9	negative selection	10341659
21378353	21378376	12	+	28162770	TF1	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	NaN	[NaN]	[329]	1	hSpCas9	negative selection	10341660
21378269	21378292	12	-	28162770	TF1	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	NaN	[NaN]	[406]	1	hSpCas9	negative selection	10341661
21378331	21378354	12	+	28162770	TF1	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	NaN	[NaN]	[613]	1	hSpCas9	negative selection	10341662
21378366	21378389	12	+	28162770	TF1	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	NaN	[NaN]	[432]	1	hSpCas9	negative selection	10341663
21373405	21373428	12	-	28162770	SKM1	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.18922555740124863	[63]	[128]	1	hSpCas9	negative selection	10511020
21378311	21378334	12	-	28162770	SKM1	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	0.9205020796856307	[25]	[86]	8	hSpCas9	negative selection	10511021
21378403	21378426	12	-	28162770	SKM1	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.6030198898294605	[107]	[289]	6	hSpCas9	negative selection	10511022
21378225	21378248	12	+	28162770	SKM1	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	1.097656193660391	[59]	[226]	8	hSpCas9	negative selection	10511023
21378233	21378256	12	+	28162770	SKM1	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.7629608026991508	[54]	[164]	7	hSpCas9	negative selection	10511024
21378344	21378367	12	-	28162770	SKM1	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	0.6579912430976083	[56]	[158]	6	hSpCas9	negative selection	10511025
21378353	21378376	12	+	28162770	SKM1	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.49992639686535684	[73]	[184]	5	hSpCas9	negative selection	10511026
21378269	21378292	12	-	28162770	SKM1	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	0.2033093905071819	[112]	[229]	2	hSpCas9	negative selection	10511027
21378331	21378354	12	+	28162770	SKM1	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.5513086756471153	[170]	[442]	5	hSpCas9	negative selection	10511028
21378366	21378389	12	+	28162770	SKM1	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.29977495264881215	[93]	[134]	-3	hSpCas9	negative selection	10511029
21373405	21373428	12	-	28162770	SKM1	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.18922555740124863	[63]	[128]	1	hSpCas9	negative selection	10680386
21378311	21378334	12	-	28162770	SKM1	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	0.9205020796856307	[25]	[86]	8	hSpCas9	negative selection	10680387
21378403	21378426	12	-	28162770	SKM1	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.6030198898294605	[107]	[289]	6	hSpCas9	negative selection	10680388
21378225	21378248	12	+	28162770	SKM1	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	1.097656193660391	[59]	[226]	8	hSpCas9	negative selection	10680389
21378233	21378256	12	+	28162770	SKM1	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.7629608026991508	[54]	[164]	7	hSpCas9	negative selection	10680390
21378344	21378367	12	-	28162770	SKM1	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	0.6579912430976083	[56]	[158]	6	hSpCas9	negative selection	10680391
21378353	21378376	12	+	28162770	SKM1	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.49992639686535684	[73]	[184]	5	hSpCas9	negative selection	10680392
21378269	21378292	12	-	28162770	SKM1	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	0.2033093905071819	[112]	[229]	2	hSpCas9	negative selection	10680393
21378331	21378354	12	+	28162770	SKM1	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.5513086756471153	[170]	[442]	5	hSpCas9	negative selection	10680394
21378366	21378389	12	+	28162770	SKM1	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.29977495264881215	[93]	[134]	-3	hSpCas9	negative selection	10680395
21373405	21373428	12	-	28162770	PL21	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.47390042691617246	[267]	[161]	4	hSpCas9	negative selection	10849752
21378311	21378334	12	-	28162770	PL21	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	-0.5800791776307697	[78]	[22]	-4	hSpCas9	negative selection	10849753
21378403	21378426	12	-	28162770	PL21	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.0993389737018282	[488]	[227]	0	hSpCas9	negative selection	10849754
21378225	21378248	12	+	28162770	PL21	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.854248276251242	[257]	[202]	7	hSpCas9	negative selection	10849755
21378233	21378256	12	+	28162770	PL21	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	-0.016435480251813683	[164]	[70]	0	hSpCas9	negative selection	10849756
21378344	21378367	12	-	28162770	PL21	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	-0.028679076006560722	[224]	[95]	0	hSpCas9	negative selection	10849757
21378353	21378376	12	+	28162770	PL21	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.8287725868674529	[281]	[217]	7	hSpCas9	negative selection	10849758
21378269	21378292	12	-	28162770	PL21	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	-0.09808421980677351	[331]	[134]	0	hSpCas9	negative selection	10849759
21378331	21378354	12	+	28162770	PL21	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.6264924269959982	[761]	[511]	5	hSpCas9	negative selection	10849760
21378366	21378389	12	+	28162770	PL21	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-1.447558641579799	[281]	[44]	-7	hSpCas9	negative selection	10849761
21373405	21373428	12	-	28162770	P31FUJ	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.9702352842772667	[267]	[616]	9	hSpCas9	negative selection	11019118
21378311	21378334	12	-	28162770	P31FUJ	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	1.1809183663924743	[136]	[364]	9	hSpCas9	negative selection	11019119
21378403	21378426	12	-	28162770	P31FUJ	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.7274715172700107	[404]	[787]	8	hSpCas9	negative selection	11019120
21378225	21378248	12	+	28162770	P31FUJ	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.4961260706864091	[215]	[357]	5	hSpCas9	negative selection	11019121
21378233	21378256	12	+	28162770	P31FUJ	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.8738579035699173	[201]	[434]	8	hSpCas9	negative selection	11019122
21378344	21378367	12	-	28162770	P31FUJ	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	0.9847038615620437	[168]	[392]	9	hSpCas9	negative selection	11019123
21378353	21378376	12	+	28162770	P31FUJ	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.23961751700043454	[381]	[529]	2	hSpCas9	negative selection	11019124
21378269	21378292	12	-	28162770	P31FUJ	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	0.6088171323698548	[528]	[947]	7	hSpCas9	negative selection	11019125
21378331	21378354	12	+	28162770	P31FUJ	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.22069817017099713	[841]	[1152]	2	hSpCas9	negative selection	11019126
21378366	21378389	12	+	28162770	P31FUJ	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.5729610363788273	[437]	[345]	-5	hSpCas9	negative selection	11019127
21373405	21373428	12	-	28162770	OCIAML5	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.09694950041719796	[143]	[277]	0	hSpCas9	negative selection	11188484
21378311	21378334	12	-	28162770	OCIAML5	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	0.39391267079006675	[77]	[184]	3	hSpCas9	negative selection	11188485
21378403	21378426	12	-	28162770	OCIAML5	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	1.191145495957302	[221]	[914]	8	hSpCas9	negative selection	11188486
21378225	21378248	12	+	28162770	OCIAML5	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.631683678498861	[122]	[343]	5	hSpCas9	negative selection	11188487
21378233	21378256	12	+	28162770	OCIAML5	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	1.3623770973569602	[77]	[361]	9	hSpCas9	negative selection	11188488
21378344	21378367	12	-	28162770	OCIAML5	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	0.7883910424488628	[84]	[264]	7	hSpCas9	negative selection	11188489
21378353	21378376	12	+	28162770	OCIAML5	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.4287228292298788	[248]	[604]	3	hSpCas9	negative selection	11188490
21378269	21378292	12	-	28162770	OCIAML5	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	0.7497451145493794	[226]	[688]	6	hSpCas9	negative selection	11188491
21378331	21378354	12	+	28162770	OCIAML5	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.6331451053042967	[478]	[1340]	5	hSpCas9	negative selection	11188492
21378366	21378389	12	+	28162770	OCIAML5	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	0.34098830541687064	[219]	[502]	3	hSpCas9	negative selection	11188493
21373405	21373428	12	-	28162770	EOL1	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.5521767370944269	[421]	[325]	5	hSpCas9	negative selection	11357850
21378311	21378334	12	-	28162770	EOL1	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	0.6615133657367405	[131]	[109]	6	hSpCas9	negative selection	11357851
21378403	21378426	12	-	28162770	EOL1	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.02352350137644632	[858]	[459]	0	hSpCas9	negative selection	11357852
21378225	21378248	12	+	28162770	EOL1	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.5149035310619094	[444]	[334]	4	hSpCas9	negative selection	11357853
21378233	21378256	12	+	28162770	EOL1	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	1.1582201177729854	[272]	[320]	8	hSpCas9	negative selection	11357854
21378344	21378367	12	-	28162770	EOL1	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	0.37974239732136117	[371]	[254]	3	hSpCas9	negative selection	11357855
21378353	21378376	12	+	28162770	EOL1	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.0185712064975756	[372]	[193]	0	hSpCas9	negative selection	11357856
21378269	21378292	12	-	28162770	EOL1	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	1.9305093298092513	[482]	[969]	9	hSpCas9	negative selection	11357857
21378331	21378354	12	+	28162770	EOL1	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	-0.4513579443756526	[884]	[340]	-3	hSpCas9	negative selection	11357858
21378366	21378389	12	+	28162770	EOL1	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.33995204326775796	[393]	[163]	-3	hSpCas9	negative selection	11357859
21373405	21373428	12	-	28162770	MOLM13	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.09349386676308091	[419]	[323]	0	hSpCas9	negative selection	11527216
21378311	21378334	12	-	28162770	MOLM13	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	1.0755719587658186	[104]	[159]	7	hSpCas9	negative selection	11527217
21378403	21378426	12	-	28162770	MOLM13	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.7934390904141992	[556]	[697]	6	hSpCas9	negative selection	11527218
21378225	21378248	12	+	28162770	MOLM13	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	1.3930807938960412	[375]	[713]	9	hSpCas9	negative selection	11527219
21378233	21378256	12	+	28162770	MOLM13	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.4394329354953507	[255]	[250]	3	hSpCas9	negative selection	11527220
21378344	21378367	12	-	28162770	MOLM13	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	-0.11926733258948917	[328]	[218]	0	hSpCas9	negative selection	11527221
21378353	21378376	12	+	28162770	MOLM13	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.43237827187020456	[488]	[261]	-3	hSpCas9	negative selection	11527222
21378269	21378292	12	-	28162770	MOLM13	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	1.1034008244291709	[429]	[667]	8	hSpCas9	negative selection	11527223
21378331	21378354	12	+	28162770	MOLM13	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.15385207227668185	[1093]	[879]	1	hSpCas9	negative selection	11527224
21378366	21378389	12	+	28162770	MOLM13	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.39253616944755326	[442]	[243]	-2	hSpCas9	negative selection	11527225
21373405	21373428	12	-	28162770	HEL	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.8166768959492925	[358]	[404]	7	hSpCas9	negative selection	11696582
21378311	21378334	12	-	28162770	HEL	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	1.1172773430278624	[94]	[131]	8	hSpCas9	negative selection	11696583
21378403	21378426	12	-	28162770	HEL	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.551849690833988	[605]	[568]	4	hSpCas9	negative selection	11696584
21378225	21378248	12	+	28162770	HEL	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.45270024987244223	[315]	[276]	4	hSpCas9	negative selection	11696585
21378233	21378256	12	+	28162770	HEL	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.8743028992350551	[223]	[262]	7	hSpCas9	negative selection	11696586
21378344	21378367	12	-	28162770	HEL	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	0.2952165556961524	[326]	[256]	2	hSpCas9	negative selection	11696587
21378353	21378376	12	+	28162770	HEL	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.11792647466576067	[504]	[350]	0	hSpCas9	negative selection	11696588
21378269	21378292	12	-	28162770	HEL	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	0.395972815311312	[387]	[326]	3	hSpCas9	negative selection	11696589
21378331	21378354	12	+	28162770	HEL	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	-0.37292576316293524	[925]	[457]	-3	hSpCas9	negative selection	11696590
21378366	21378389	12	+	28162770	HEL	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.3486480376949349	[333]	[167]	-2	hSpCas9	negative selection	11696591
21373405	21373428	12	-	28162770	MV411	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.9318109730083424	[256]	[412]	8	hSpCas9	negative selection	11865948
21378311	21378334	12	-	28162770	MV411	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	1.6989466067267656	[82]	[226]	9	hSpCas9	negative selection	11865949
21378403	21378426	12	-	28162770	MV411	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.5435696447928	[473]	[581]	5	hSpCas9	negative selection	11865950
21378225	21378248	12	+	28162770	MV411	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	1.0702445488764238	[198]	[351]	8	hSpCas9	negative selection	11865951
21378233	21378256	12	+	28162770	MV411	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.8713941831197952	[145]	[224]	7	hSpCas9	negative selection	11865952
21378344	21378367	12	-	28162770	MV411	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	0.3753123733349333	[204]	[223]	3	hSpCas9	negative selection	11865953
21378353	21378376	12	+	28162770	MV411	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	1.365865496853316	[262]	[570]	9	hSpCas9	negative selection	11865954
21378269	21378292	12	-	28162770	MV411	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	0.20742187193489603	[328]	[319]	1	hSpCas9	negative selection	11865955
21378331	21378354	12	+	28162770	MV411	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.3886834762185267	[699]	[771]	3	hSpCas9	negative selection	11865956
21378366	21378389	12	+	28162770	MV411	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	0.34090190536448106	[253]	[270]	3	hSpCas9	negative selection	11865957
21373405	21373428	12	-	28162770	MONOMAC1	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.5894191816721629	[148]	[256]	6	hSpCas9	negative selection	12035314
21378311	21378334	12	-	28162770	MONOMAC1	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	-0.159562141640891	[37]	[38]	-1	hSpCas9	negative selection	12035315
21378403	21378426	12	-	28162770	MONOMAC1	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	1.0012327800767205	[223]	[513]	8	hSpCas9	negative selection	12035316
21378225	21378248	12	+	28162770	MONOMAC1	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.026050650246930762	[150]	[169]	0	hSpCas9	negative selection	12035317
21378233	21378256	12	+	28162770	MONOMAC1	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.35108888548123107	[118]	[173]	3	hSpCas9	negative selection	12035318
21378344	21378367	12	-	28162770	MONOMAC1	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	0.6223909072986255	[135]	[239]	6	hSpCas9	negative selection	12035319
21378353	21378376	12	+	28162770	MONOMAC1	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.18033023425323513	[193]	[251]	1	hSpCas9	negative selection	12035320
21378269	21378292	12	-	28162770	MONOMAC1	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	1.0730523163081904	[237]	[573]	8	hSpCas9	negative selection	12035321
21378331	21378354	12	+	28162770	MONOMAC1	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	0.22539278644932526	[437]	[586]	2	hSpCas9	negative selection	12035322
21378366	21378389	12	+	28162770	MONOMAC1	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.21324707424081274	[178]	[176]	-2	hSpCas9	negative selection	12035323
21373405	21373428	12	-	28162770	OCIAML2	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.5211496679528704	[43]	[349]	5	hSpCas9	negative selection	12204680
21378311	21378334	12	-	28162770	OCIAML2	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	1.5133696960641234	[16]	[268]	9	hSpCas9	negative selection	12204681
21378403	21378426	12	-	28162770	OCIAML2	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	0.8965791489460674	[68]	[711]	8	hSpCas9	negative selection	12204682
21378225	21378248	12	+	28162770	OCIAML2	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	0.8887729750638641	[37]	[389]	8	hSpCas9	negative selection	12204683
21378233	21378256	12	+	28162770	OCIAML2	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.6022707218052863	[40]	[344]	6	hSpCas9	negative selection	12204684
21378344	21378367	12	-	28162770	OCIAML2	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	-0.04916605680388428	[41]	[224]	0	hSpCas9	negative selection	12204685
21378353	21378376	12	+	28162770	OCIAML2	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	0.688067920776897	[42]	[383]	6	hSpCas9	negative selection	12204686
21378269	21378292	12	-	28162770	OCIAML2	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	0.3367250968154428	[59]	[419]	3	hSpCas9	negative selection	12204687
21378331	21378354	12	+	28162770	OCIAML2	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	-0.016830074684194285	[139]	[766]	0	hSpCas9	negative selection	12204688
21378366	21378389	12	+	28162770	OCIAML2	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.008628846992730699	[50]	[280]	0	hSpCas9	negative selection	12204689
21373405	21373428	12	-	28162770	OCIAML3	viability	CAATGGGTGTAGCTTTCAGATGG	IAPP	ENSG00000121351	0.24773027575910467	[76]	[275]	2	hSpCas9	negative selection	12374046
21378311	21378334	12	-	28162770	OCIAML3	viability	AATGGCACCAAAGTTGTTGCTGG	IAPP	ENSG00000121351	1.5538910547881502	[21]	[194]	9	hSpCas9	negative selection	12374047
21378403	21378426	12	-	28162770	OCIAML3	viability	TAAAGGGGCAAGTAATTCAGTGG	IAPP	ENSG00000121351	-0.019692383802515367	[135]	[404]	0	hSpCas9	negative selection	12374048
21378225	21378248	12	+	28162770	OCIAML3	viability	CCATGTTACCAGTCATCAGGTGG	IAPP	ENSG00000121351	-0.2283581680074827	[77]	[200]	-2	hSpCas9	negative selection	12374049
21378233	21378256	12	+	28162770	OCIAML3	viability	CCAGTCATCAGGTGGAAAAGCGG	IAPP	ENSG00000121351	0.006384900966599105	[61]	[187]	0	hSpCas9	negative selection	12374050
21378344	21378367	12	-	28162770	OCIAML3	viability	ATATGTATTGGATCCCACGTTGG	IAPP	ENSG00000121351	-0.11535404174934766	[60]	[169]	-1	hSpCas9	negative selection	12374051
21378353	21378376	12	+	28162770	OCIAML3	viability	GATCCAATACATATGGCAAGAGG	IAPP	ENSG00000121351	-0.5268934444656261	[83]	[175]	-4	hSpCas9	negative selection	12374052
21378269	21378292	12	-	28162770	OCIAML3	viability	CAGGCGCTGCGTTGCACATGTGG	IAPP	ENSG00000121351	0.7144372251995771	[85]	[425]	6	hSpCas9	negative selection	12374053
21378331	21378354	12	+	28162770	OCIAML3	viability	ATTCTCTCATCTACCAACGTGGG	IAPP	ENSG00000121351	-0.08977641171586392	[195]	[555]	0	hSpCas9	negative selection	12374054
21378366	21378389	12	+	28162770	OCIAML3	viability	TGGCAAGAGGAATGCAGTAGAGG	IAPP	ENSG00000121351	-0.9996464416007573	[101]	[153]	-6	hSpCas9	negative selection	12374055