Crispr

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 3417
  • Symbol: IDH1
  • Description: isocitrate dehydrogenase (NADP(+)) 1
DataSource: http://genomecrispr.dkfz.de/#!/results/IDH1

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Start The end chr strand pubmed cellline condition sequence symbol ensg log2fc rc_initial rc_final effect cas screentype index
208245357 208245380 2 - 26472758 Jiyoye viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.9744589595057567 [184] [70] -6 hSpCas9 negative selection 75759
208243510 208243533 2 - 26472758 Jiyoye viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 3.2349944061231932 [9] [70] 9 hSpCas9 negative selection 75760
208242078 208242101 2 - 26472758 Jiyoye viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 0.7635369734571098 [206] [264] 5 hSpCas9 negative selection 75761
208239925 208239948 2 - 26472758 Jiyoye viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 0.7879197032308396 [148] [193] 5 hSpCas9 negative selection 75762
208251432 208251455 2 + 26472758 Jiyoye viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 -0.5683022993600577 [349] [177] -4 hSpCas9 negative selection 75763
208248409 208248432 2 + 26472758 Jiyoye viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 0.7482122993409404 [164] [208] 5 hSpCas9 negative selection 75764
208242053 208242076 2 - 26472758 Jiyoye viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 1.1441409756720795 [23] [39] 7 hSpCas9 negative selection 75765
208239909 208239932 2 + 26472758 Jiyoye viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 -0.4022186858253292 [176] [100] -3 hSpCas9 negative selection 75766
208239862 208239885 2 - 26472758 Jiyoye viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 -0.16189574644539162 [315] [212] -1 hSpCas9 negative selection 75767
208243582 208243605 2 - 26472758 Jiyoye viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.18760900424818883 [169] [145] 1 hSpCas9 negative selection 75768
208245357 208245380 2 - 26472758 KBM7 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.5870664379836925 [299,167] [33,104] -5 hSpCas9 negative selection 266877
208243510 208243533 2 - 26472758 KBM7 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 0.34592595509863566 [261,219] [87,192] 3 hSpCas9 negative selection 266878
208242078 208242101 2 - 26472758 KBM7 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 -0.30420701058258115 [1183,1251] [459,473] -3 hSpCas9 negative selection 266879
208239925 208239948 2 - 26472758 KBM7 viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.12722317297207075 [939,578] [412,237] -1 hSpCas9 negative selection 266880
208251432 208251455 2 + 26472758 KBM7 viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.2522629387738091 [1130,951] [722,453] 2 hSpCas9 negative selection 266881
208248409 208248432 2 + 26472758 KBM7 viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 0.41726181086131287 [500,456] [379,229] 4 hSpCas9 negative selection 266882
208242053 208242076 2 - 26472758 KBM7 viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 -0.0913553243451839 [154,175] [47,96] -1 hSpCas9 negative selection 266883
208239909 208239932 2 + 26472758 KBM7 viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 0.502709961723545 [568,344] [235,353] 5 hSpCas9 negative selection 266884
208239862 208239885 2 - 26472758 KBM7 viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 0.2557106360229655 [1974,1685] [1169,893] 2 hSpCas9 negative selection 266885
208243582 208243605 2 - 26472758 KBM7 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.7971285670043823 [819,899] [465,926] 8 hSpCas9 negative selection 266886
208245357 208245380 2 - 26472758 Raji viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.030567938322768384 [134] [31] 0 hSpCas9 negative selection 457995
208243510 208243533 2 - 26472758 Raji viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 0.7744002519772413 [130] [51] 7 hSpCas9 negative selection 457996
208242078 208242101 2 - 26472758 Raji viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 0.9644255815315563 [317] [143] 8 hSpCas9 negative selection 457997
208239925 208239948 2 - 26472758 Raji viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.10206983025535041 [258] [55] -1 hSpCas9 negative selection 457998
208251432 208251455 2 + 26472758 Raji viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.7205596382594059 [556] [212] 6 hSpCas9 negative selection 457999
208248409 208248432 2 + 26472758 Raji viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 1.180756721703819 [229] [120] 9 hSpCas9 negative selection 458000
208242053 208242076 2 - 26472758 Raji viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 1.8025289538451785 [41] [33] 9 hSpCas9 negative selection 458001
208239909 208239932 2 + 26472758 Raji viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 -0.17584103018327885 [330] [67] -1 hSpCas9 negative selection 458002
208239862 208239885 2 - 26472758 Raji viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 0.36322243980318936 [803] [239] 3 hSpCas9 negative selection 458003
208243582 208243605 2 - 26472758 Raji viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.0234317570411402 [512] [120] 0 hSpCas9 negative selection 458004
208245357 208245380 2 - 26472758 K562 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 1.081623577470611 [163] [292] 8 hSpCas9 negative selection 649113
208243510 208243533 2 - 26472758 K562 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 0.19379265459647882 [318] [307] 1 hSpCas9 negative selection 649114
208242078 208242101 2 - 26472758 K562 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 0.5237754388021736 [790] [959] 4 hSpCas9 negative selection 649115
208239925 208239948 2 - 26472758 K562 viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.015013441487151391 [479] [400] 0 hSpCas9 negative selection 649116
208251432 208251455 2 + 26472758 K562 viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.3351375846329342 [754] [803] 2 hSpCas9 negative selection 649117
208248409 208248432 2 + 26472758 K562 viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 0.3034271393983699 [502] [523] 2 hSpCas9 negative selection 649118
208242053 208242076 2 - 26472758 K562 viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 0.6321488809495552 [119] [156] 5 hSpCas9 negative selection 649119
208239909 208239932 2 + 26472758 K562 viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 -0.3773805412350808 [356] [231] -3 hSpCas9 negative selection 649120
208239862 208239885 2 - 26472758 K562 viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 0.5492045390234466 [998] [1233] 4 hSpCas9 negative selection 649121
208243582 208243605 2 - 26472758 K562 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.4989638933349184 [766] [914] 4 hSpCas9 negative selection 649122
208242081 208242104 2 - 26627737 DLD1 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.8574091753624073 [620] [350,403,308] 8 hSpCas9 negative selection 810162
208242081 208242104 2 - 26627737 GBM cells viability after 5 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.19305881325951002 [366] [217,231] 3 hSpCas9 negative selection 892477
208242081 208242104 2 - 26627737 GBM cells viability after 13 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.03412496122279063 [366] [167,215] 0 hSpCas9 negative selection 974792
208242081 208242104 2 - 26627737 GBM cells viability after 21 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.44505113815044695 [366] [272,269] 4 hSpCas9 negative selection 1057107
208242081 208242104 2 - 26627737 RPE1 viability after 9 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.16636502776865403 [1522] [423,425] -1 hSpCas9 negative selection 1139422
208242081 208242104 2 - 26627737 RPE1 viability after 12 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.3642097036214872 [1522] [515,537] 2 hSpCas9 negative selection 1221737
208242081 208242104 2 - 26627737 RPE1 viability after 15 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.043623455474834594 [1522] [305,525] 0 hSpCas9 negative selection 1304052
208242081 208242104 2 - 26627737 RPE1 viability after 18 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.2618645164580331 [1522] [219,473] -2 hSpCas9 negative selection 1386367
208242081 208242104 2 - 26627737 HeLa viability after 8 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 1.028831924828712 [377] [353,278,374] 7 hSpCas9 negative selection 1468682
208242081 208242104 2 - 26627737 HeLa viability after 12 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.9293949670180593 [377] [287,346,251] 7 hSpCas9 negative selection 1550997
208242081 208242104 2 - 26627737 HeLa viability after 15 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 1.3872133678531424 [377] [367,340,506] 8 hSpCas9 negative selection 1633312
208242081 208242104 2 - 26627737 HeLa viability after 18 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 1.40915417650854 [377] [251,290,506] 8 hSpCas9 negative selection 1715627
208242081 208242104 2 - 26627737 HCT116 viability after 6 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.6774481437938358 [1634] [132,175] -4 hSpCas9 negative selection 1797942
208242081 208242104 2 - 26627737 HCT116 viability after 8 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.6281740630761995 [297] [189,212,355] 6 hSpCas9 negative selection 1880257
208242081 208242104 2 - 26627737 HCT116 viability after 9 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.38953625892643595 [1634] [486,638] 3 hSpCas9 negative selection 1962572
208242081 208242104 2 - 26627737 HCT116 viability after 12 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.2824619953711273 [297] [172,191,207] 3 hSpCas9 negative selection 2044887
208242081 208242104 2 - 26627737 HCT116 viability after 15 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.8365639680845205 [297] [303,334,277] 7 hSpCas9 negative selection 2127202
208242081 208242104 2 - 26627737 HCT116 viability after 18 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 1.2978769523087226 [297] [345,405,304] 8 hSpCas9 negative selection 2209517
208254548 208254571 2 - 25494202 A375 resistance to PLX-4720 (puromycin) AACGTGCAGCAGCTGGGGGCTGG IDH1 ENSG00000138413 -0.21892191477054745 [67,1] [10,0] -1 dCas9-VP64 positive selection 2421677
208254576 208254599 2 - 25494202 A375 resistance to PLX-4720 (puromycin) GACTAAGCCTGGAGTGTAGGAGG IDH1 ENSG00000138413 2.0624077457666536 [66,2] [54,5] 7 dCas9-VP64 positive selection 2421678
208254622 208254645 2 - 25494202 A375 resistance to PLX-4720 (puromycin) TGGGTTGGAAAATCGAGGGGTGG IDH1 ENSG00000138413 0.6739150657222996 [1,4] [0,0] 3 dCas9-VP64 positive selection 2421679
208254455 208254478 2 + 25494202 A375 resistance to PLX-4720 (puromycin) CCCTGGCGGACGCGAGGGATCGG IDH1 ENSG00000138413 0.763494576265188 [5,56] [1,22] 3 dCas9-VP64 positive selection 2421680
208254429 208254452 2 - 25494202 A375 resistance to PLX-4720 (puromycin) GTGGAGGGGCGGAGCTCCAGCGG IDH1 ENSG00000138413 -0.8155836008465349 [37,18] [1,3] -4 dCas9-VP64 positive selection 2421681
208254406 208254429 2 + 25494202 A375 resistance to PLX-4720 (puromycin) TGGCCTAGCGACCCCTCTGAAGG IDH1 ENSG00000138413 1.1345388952578186 [29,7] [13,2] 4 dCas9-VP64 positive selection 2421682
208255223 208255246 2 + 25494202 A375 resistance to PLX-4720 (puromycin) GGCGTGGCCACAGTCAAAGATGG IDH1 ENSG00000138413 -0.13877723159423971 [623,82] [99,36] 0 dCas9-VP64 positive selection 2438829
208254548 208254571 2 - 25494202 A375 resistance to PLX-4720 (zeocin) AACGTGCAGCAGCTGGGGGCTGG IDH1 ENSG00000138413 -0.29531138843632726 [81,306] [16,82] -3 dCas9-VP64 positive selection 2516932
208254576 208254599 2 - 25494202 A375 resistance to PLX-4720 (zeocin) GACTAAGCCTGGAGTGTAGGAGG IDH1 ENSG00000138413 1.2114246795477275 [51,68] [39,50] 7 dCas9-VP64 positive selection 2516933
208254622 208254645 2 - 25494202 A375 resistance to PLX-4720 (zeocin) TGGGTTGGAAAATCGAGGGGTGG IDH1 ENSG00000138413 -0.7737874794179482 [44,90] [6,17] -7 dCas9-VP64 positive selection 2516934
208254455 208254478 2 + 25494202 A375 resistance to PLX-4720 (zeocin) CCCTGGCGGACGCGAGGGATCGG IDH1 ENSG00000138413 0.1136334664021883 [29,28] [6,12] 0 dCas9-VP64 positive selection 2516935
208254429 208254452 2 - 25494202 A375 resistance to PLX-4720 (zeocin) GTGGAGGGGCGGAGCTCCAGCGG IDH1 ENSG00000138413 -0.7822960666906846 [86,24] [8,10] -7 dCas9-VP64 positive selection 2516936
208254406 208254429 2 + 25494202 A375 resistance to PLX-4720 (zeocin) TGGCCTAGCGACCCCTCTGAAGG IDH1 ENSG00000138413 1.1185050803730137 [7,28] [4,19] 7 dCas9-VP64 positive selection 2516937
208255223 208255246 2 + 25494202 A375 resistance to PLX-4720 (zeocin) GGCGTGGCCACAGTCAAAGATGG IDH1 ENSG00000138413 -0.6353081380338738 [265,35] [49,14] -6 dCas9-VP64 positive selection 2534084
208239893 208239916 2 + 27260157 DLD1 viability TCTGGTACATGCGGTAGTGACGG IDH1 ENSG00000138413 -0.60898975699041 [] [] -5 hSpCas9 negative selection 2574070
208248468 208248491 2 + 27260157 DLD1 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 1.58019933771867 [] [] 9 hSpCas9 negative selection 2574160
208243510 208243533 2 - 27260157 DLD1 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 0.279186193283627 [] [] 4 hSpCas9 negative selection 2575446
208245346 208245369 2 - 27260157 DLD1 viability ACCAAGTGACGGAACCCAAAAGG IDH1 ENSG00000138413 1.16594291734711 [] [] 9 hSpCas9 negative selection 2579526
208248529 208248552 2 + 27260157 DLD1 viability TCCTCAACCCTCTTCTCATCAGG IDH1 ENSG00000138413 0.470828661435622 [] [] 8 hSpCas9 negative selection 2579609
208248382 208248405 2 + 27260157 DLD1 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.328660448067765 [] [] 4 hSpCas9 negative selection 2582845
208248374 208248397 2 - 27260157 DLD1 viability CATAGGTCGTCATGCTTATGGGG IDH1 ENSG00000138413 -0.245832887214959 [] [] -2 hSpCas9 negative selection 2583292
208248540 208248563 2 + 27260157 DLD1 viability CTTCTCATCAGGAGTGATAGTGG IDH1 ENSG00000138413 0.431600392951816 [] [] 7 hSpCas9 negative selection 2585890
208242078 208242101 2 - 27260157 DLD1 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 -0.191549753478337 [] [] -1 hSpCas9 negative selection 2605568
208239957 208239980 2 + 27260157 DLD1 viability ATCTGGACAAACCAGCACGCTGG IDH1 ENSG00000138413 0.592646712490647 [] [] 8 hSpCas9 negative selection 2605891
208245353 208245376 2 + 27260157 DLD1 viability GGTTCCGTCACTTGGTGTGTAGG IDH1 ENSG00000138413 -1.64713571689566 [] [] -8 hSpCas9 negative selection 2611192
208239884 208239907 2 - 27260157 DLD1 viability CCGCATGTACCAGAAAGGACAGG IDH1 ENSG00000138413 0.0045177990689788 [] [] 0 hSpCas9 negative selection 2614885
208243512 208243535 2 + 27260157 DLD1 viability AACCCTTAGACAGAGCCATTTGG IDH1 ENSG00000138413 0.13402127432175 [] [] 3 hSpCas9 negative selection 2619284
208242000 208242023 2 - 27260157 DLD1 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.404263393118348 [] [] 4 hSpCas9 negative selection 2621647
208243595 208243618 2 - 27260157 DLD1 viability TTCTCCTCTACAGAAGGTGGTGG IDH1 ENSG00000138413 1.05205475025003 [] [] 9 hSpCas9 negative selection 2641233
208248530 208248553 2 - 27260157 DLD1 viability TCCTGATGAGAAGAGGGTTGAGG IDH1 ENSG00000138413 -1.3465463253222 [] [] -8 hSpCas9 negative selection 2641776
208239875 208239898 2 + 27260157 DLD1 viability TGGACGTCTCCTGTCCTTTCTGG IDH1 ENSG00000138413 0.738097643848455 [] [] 8 hSpCas9 negative selection 2642430
208243582 208243605 2 - 27260157 DLD1 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 -1.75140167113872 [] [] -8 hSpCas9 negative selection 2644824
208239955 208239978 2 - 27260157 DLD1 viability AGCGTGCTGGTTTGTCCAGATGG IDH1 ENSG00000138413 0.424438994045257 [] [] 7 hSpCas9 negative selection 2647423
208239968 208239991 2 - 27260157 DLD1 viability CGGCATGATGACCAGCGTGCTGG IDH1 ENSG00000138413 0.643911142533114 [] [] 8 hSpCas9 negative selection 2647914
208239893 208239916 2 + 27260157 HT1080 viability TCTGGTACATGCGGTAGTGACGG IDH1 ENSG00000138413 -1.23244780011569 [] [] -9 hSpCas9 negative selection 2650200
208248468 208248491 2 + 27260157 HT1080 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 -0.0257789809879786 [] [] 0 hSpCas9 negative selection 2650290
208243510 208243533 2 - 27260157 HT1080 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 -0.640721282112483 [] [] -8 hSpCas9 negative selection 2651576
208245346 208245369 2 - 27260157 HT1080 viability ACCAAGTGACGGAACCCAAAAGG IDH1 ENSG00000138413 0.923954367825285 [] [] 7 hSpCas9 negative selection 2655656
208248529 208248552 2 + 27260157 HT1080 viability TCCTCAACCCTCTTCTCATCAGG IDH1 ENSG00000138413 -0.506632464847192 [] [] -7 hSpCas9 negative selection 2655739
208248382 208248405 2 + 27260157 HT1080 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.968474895873214 [] [] 7 hSpCas9 negative selection 2658975
208248374 208248397 2 - 27260157 HT1080 viability CATAGGTCGTCATGCTTATGGGG IDH1 ENSG00000138413 -1.01197540970954 [] [] -8 hSpCas9 negative selection 2659422
208248540 208248563 2 + 27260157 HT1080 viability CTTCTCATCAGGAGTGATAGTGG IDH1 ENSG00000138413 0.64960254548285 [] [] 5 hSpCas9 negative selection 2662020
208242078 208242101 2 - 27260157 HT1080 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 -0.340123847781007 [] [] -7 hSpCas9 negative selection 2681698
208239957 208239980 2 + 27260157 HT1080 viability ATCTGGACAAACCAGCACGCTGG IDH1 ENSG00000138413 -0.205088540303413 [] [] 0 hSpCas9 negative selection 2682021
208245353 208245376 2 + 27260157 HT1080 viability GGTTCCGTCACTTGGTGTGTAGG IDH1 ENSG00000138413 -1.1102658490918 [] [] -8 hSpCas9 negative selection 2687322
208239884 208239907 2 - 27260157 HT1080 viability CCGCATGTACCAGAAAGGACAGG IDH1 ENSG00000138413 0.276045518638103 [] [] 2 hSpCas9 negative selection 2691015
208243512 208243535 2 + 27260157 HT1080 viability AACCCTTAGACAGAGCCATTTGG IDH1 ENSG00000138413 0.651898422288676 [] [] 6 hSpCas9 negative selection 2695414
208242000 208242023 2 - 27260157 HT1080 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.548338499950542 [] [] 5 hSpCas9 negative selection 2697777
208243595 208243618 2 - 27260157 HT1080 viability TTCTCCTCTACAGAAGGTGGTGG IDH1 ENSG00000138413 -0.230794232357792 [] [] 0 hSpCas9 negative selection 2717363
208248530 208248553 2 - 27260157 HT1080 viability TCCTGATGAGAAGAGGGTTGAGG IDH1 ENSG00000138413 -1.96195189460073 [] [] -9 hSpCas9 negative selection 2717906
208239875 208239898 2 + 27260157 HT1080 viability TGGACGTCTCCTGTCCTTTCTGG IDH1 ENSG00000138413 0.277005674067438 [] [] 2 hSpCas9 negative selection 2718560
208243582 208243605 2 - 27260157 HT1080 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 -1.18637294886766 [] [] -8 hSpCas9 negative selection 2720954
208239955 208239978 2 - 27260157 HT1080 viability AGCGTGCTGGTTTGTCCAGATGG IDH1 ENSG00000138413 -0.223181002097226 [] [] 0 hSpCas9 negative selection 2723553
208239968 208239991 2 - 27260157 HT1080 viability CGGCATGATGACCAGCGTGCTGG IDH1 ENSG00000138413 -0.00430278226657238 [] [] 0 hSpCas9 negative selection 2724044
208239893 208239916 2 + 27260157 MKN45 viability TCTGGTACATGCGGTAGTGACGG IDH1 ENSG00000138413 -0.841333033709232 [] [] -7 hSpCas9 negative selection 2726330
208248468 208248491 2 + 27260157 MKN45 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.874881968973661 [] [] 8 hSpCas9 negative selection 2726420
208243510 208243533 2 - 27260157 MKN45 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 -0.178606089214546 [] [] 0 hSpCas9 negative selection 2727706
208245346 208245369 2 - 27260157 MKN45 viability ACCAAGTGACGGAACCCAAAAGG IDH1 ENSG00000138413 1.54959630209818 [] [] 9 hSpCas9 negative selection 2731786
208248529 208248552 2 + 27260157 MKN45 viability TCCTCAACCCTCTTCTCATCAGG IDH1 ENSG00000138413 0.621012139014274 [] [] 7 hSpCas9 negative selection 2731869
208248382 208248405 2 + 27260157 MKN45 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.466827058117319 [] [] 6 hSpCas9 negative selection 2735105
208248374 208248397 2 - 27260157 MKN45 viability CATAGGTCGTCATGCTTATGGGG IDH1 ENSG00000138413 -0.791451513256705 [] [] -7 hSpCas9 negative selection 2735552
208248540 208248563 2 + 27260157 MKN45 viability CTTCTCATCAGGAGTGATAGTGG IDH1 ENSG00000138413 0.614005830380157 [] [] 7 hSpCas9 negative selection 2738150
208242078 208242101 2 - 27260157 MKN45 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 -0.477942328274208 [] [] -6 hSpCas9 negative selection 2757828
208239957 208239980 2 + 27260157 MKN45 viability ATCTGGACAAACCAGCACGCTGG IDH1 ENSG00000138413 0.666851593983082 [] [] 7 hSpCas9 negative selection 2758151
208245353 208245376 2 + 27260157 MKN45 viability GGTTCCGTCACTTGGTGTGTAGG IDH1 ENSG00000138413 -0.465868126732891 [] [] -6 hSpCas9 negative selection 2763452
208239884 208239907 2 - 27260157 MKN45 viability CCGCATGTACCAGAAAGGACAGG IDH1 ENSG00000138413 0.0427099370956888 [] [] 0 hSpCas9 negative selection 2767145
208243512 208243535 2 + 27260157 MKN45 viability AACCCTTAGACAGAGCCATTTGG IDH1 ENSG00000138413 0.311946795439088 [] [] 5 hSpCas9 negative selection 2771544
208242000 208242023 2 - 27260157 MKN45 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.397651865292453 [] [] 6 hSpCas9 negative selection 2773907
208243595 208243618 2 - 27260157 MKN45 viability TTCTCCTCTACAGAAGGTGGTGG IDH1 ENSG00000138413 0.725167604215876 [] [] 7 hSpCas9 negative selection 2793493
208248530 208248553 2 - 27260157 MKN45 viability TCCTGATGAGAAGAGGGTTGAGG IDH1 ENSG00000138413 -2.05050033055264 [] [] -9 hSpCas9 negative selection 2794036
208239875 208239898 2 + 27260157 MKN45 viability TGGACGTCTCCTGTCCTTTCTGG IDH1 ENSG00000138413 0.920927177059816 [] [] 8 hSpCas9 negative selection 2794690
208243582 208243605 2 - 27260157 MKN45 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 -1.60413586955678 [] [] -9 hSpCas9 negative selection 2797084
208239955 208239978 2 - 27260157 MKN45 viability AGCGTGCTGGTTTGTCCAGATGG IDH1 ENSG00000138413 0.138680210180701 [] [] 5 hSpCas9 negative selection 2799683
208239968 208239991 2 - 27260157 MKN45 viability CGGCATGATGACCAGCGTGCTGG IDH1 ENSG00000138413 0.430401103900911 [] [] 6 hSpCas9 negative selection 2800174
208239893 208239916 2 + 27260157 RKO viability TCTGGTACATGCGGTAGTGACGG IDH1 ENSG00000138413 -0.297875902603239 [] [] -6 hSpCas9 negative selection 2802460
208248468 208248491 2 + 27260157 RKO viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 -0.334772558930213 [] [] -6 hSpCas9 negative selection 2802550
208243510 208243533 2 - 27260157 RKO viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 0.275600970473335 [] [] 1 hSpCas9 negative selection 2803836
208245346 208245369 2 - 27260157 RKO viability ACCAAGTGACGGAACCCAAAAGG IDH1 ENSG00000138413 0.812044241964414 [] [] 8 hSpCas9 negative selection 2807916
208248529 208248552 2 + 27260157 RKO viability TCCTCAACCCTCTTCTCATCAGG IDH1 ENSG00000138413 -0.599106614250959 [] [] -7 hSpCas9 negative selection 2807999
208248382 208248405 2 + 27260157 RKO viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.593536799753756 [] [] 3 hSpCas9 negative selection 2811235
208248374 208248397 2 - 27260157 RKO viability CATAGGTCGTCATGCTTATGGGG IDH1 ENSG00000138413 -0.860154384787232 [] [] -8 hSpCas9 negative selection 2811682
208248540 208248563 2 + 27260157 RKO viability CTTCTCATCAGGAGTGATAGTGG IDH1 ENSG00000138413 -0.897485242659721 [] [] -8 hSpCas9 negative selection 2814280
208242078 208242101 2 - 27260157 RKO viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 -0.655251276893574 [] [] -7 hSpCas9 negative selection 2833958
208239957 208239980 2 + 27260157 RKO viability ATCTGGACAAACCAGCACGCTGG IDH1 ENSG00000138413 0.505022384791418 [] [] 2 hSpCas9 negative selection 2834281
208245353 208245376 2 + 27260157 RKO viability GGTTCCGTCACTTGGTGTGTAGG IDH1 ENSG00000138413 -0.391625147610332 [] [] -6 hSpCas9 negative selection 2839582
208239884 208239907 2 - 27260157 RKO viability CCGCATGTACCAGAAAGGACAGG IDH1 ENSG00000138413 -0.218622434554759 [] [] -1 hSpCas9 negative selection 2843275
208243512 208243535 2 + 27260157 RKO viability AACCCTTAGACAGAGCCATTTGG IDH1 ENSG00000138413 -0.141782430774818 [] [] 0 hSpCas9 negative selection 2847674
208242000 208242023 2 - 27260157 RKO viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.575390771755359 [] [] 3 hSpCas9 negative selection 2850037
208243595 208243618 2 - 27260157 RKO viability TTCTCCTCTACAGAAGGTGGTGG IDH1 ENSG00000138413 -0.279916124752753 [] [] -1 hSpCas9 negative selection 2869623
208248530 208248553 2 - 27260157 RKO viability TCCTGATGAGAAGAGGGTTGAGG IDH1 ENSG00000138413 -1.73026647569124 [] [] -9 hSpCas9 negative selection 2870166
208239875 208239898 2 + 27260157 RKO viability TGGACGTCTCCTGTCCTTTCTGG IDH1 ENSG00000138413 0.651538822530574 [] [] 3 hSpCas9 negative selection 2870820
208243582 208243605 2 - 27260157 RKO viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 -1.29227404996151 [] [] -8 hSpCas9 negative selection 2873214
208239955 208239978 2 - 27260157 RKO viability AGCGTGCTGGTTTGTCCAGATGG IDH1 ENSG00000138413 0.352029159010972 [] [] 2 hSpCas9 negative selection 2875813
208239968 208239991 2 - 27260157 RKO viability CGGCATGATGACCAGCGTGCTGG IDH1 ENSG00000138413 0.225828286580843 [] [] 1 hSpCas9 negative selection 2876304
208239893 208239916 2 + 27260157 SF268 viability TCTGGTACATGCGGTAGTGACGG IDH1 ENSG00000138413 -1.29604196230928 [] [] -7 hSpCas9 negative selection 2878590
208248468 208248491 2 + 27260157 SF268 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.224065478149424 [] [] 3 hSpCas9 negative selection 2878680
208243510 208243533 2 - 27260157 SF268 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 -0.726344262342944 [] [] -5 hSpCas9 negative selection 2879966
208245346 208245369 2 - 27260157 SF268 viability ACCAAGTGACGGAACCCAAAAGG IDH1 ENSG00000138413 0.960112837774913 [] [] 9 hSpCas9 negative selection 2884046
208248529 208248552 2 + 27260157 SF268 viability TCCTCAACCCTCTTCTCATCAGG IDH1 ENSG00000138413 -0.291352674764353 [] [] -2 hSpCas9 negative selection 2884129
208248382 208248405 2 + 27260157 SF268 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 -0.525508688721649 [] [] -4 hSpCas9 negative selection 2887365
208248374 208248397 2 - 27260157 SF268 viability CATAGGTCGTCATGCTTATGGGG IDH1 ENSG00000138413 -1.15113099502573 [] [] -7 hSpCas9 negative selection 2887812
208248540 208248563 2 + 27260157 SF268 viability CTTCTCATCAGGAGTGATAGTGG IDH1 ENSG00000138413 -0.154491086662597 [] [] -1 hSpCas9 negative selection 2890410
208242078 208242101 2 - 27260157 SF268 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 -0.493485319517464 [] [] -4 hSpCas9 negative selection 2910088
208239957 208239980 2 + 27260157 SF268 viability ATCTGGACAAACCAGCACGCTGG IDH1 ENSG00000138413 0.0486942089841325 [] [] 0 hSpCas9 negative selection 2910411
208245353 208245376 2 + 27260157 SF268 viability GGTTCCGTCACTTGGTGTGTAGG IDH1 ENSG00000138413 -1.39649689282621 [] [] -8 hSpCas9 negative selection 2915712
208239884 208239907 2 - 27260157 SF268 viability CCGCATGTACCAGAAAGGACAGG IDH1 ENSG00000138413 -0.556511928330259 [] [] -4 hSpCas9 negative selection 2919405
208243512 208243535 2 + 27260157 SF268 viability AACCCTTAGACAGAGCCATTTGG IDH1 ENSG00000138413 -0.0682068700932837 [] [] 0 hSpCas9 negative selection 2923804
208242000 208242023 2 - 27260157 SF268 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.806305400752518 [] [] 8 hSpCas9 negative selection 2926167
208243595 208243618 2 - 27260157 SF268 viability TTCTCCTCTACAGAAGGTGGTGG IDH1 ENSG00000138413 -0.0153574534067794 [] [] 0 hSpCas9 negative selection 2945753
208248530 208248553 2 - 27260157 SF268 viability TCCTGATGAGAAGAGGGTTGAGG IDH1 ENSG00000138413 -1.41294484184151 [] [] -8 hSpCas9 negative selection 2946296
208239875 208239898 2 + 27260157 SF268 viability TGGACGTCTCCTGTCCTTTCTGG IDH1 ENSG00000138413 -0.00981474388403256 [] [] 0 hSpCas9 negative selection 2946950
208243582 208243605 2 - 27260157 SF268 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 -1.0717368534446 [] [] -7 hSpCas9 negative selection 2949344
208239955 208239978 2 - 27260157 SF268 viability AGCGTGCTGGTTTGTCCAGATGG IDH1 ENSG00000138413 0.167904366654973 [] [] 0 hSpCas9 negative selection 2951943
208239968 208239991 2 - 27260157 SF268 viability CGGCATGATGACCAGCGTGCTGG IDH1 ENSG00000138413 -0.655510974649904 [] [] -5 hSpCas9 negative selection 2952434
208248410 208248433 2 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 -0.04453732599798893 [2,2] [3,1] 0 hSpCas9 positive selection 2994710
208245357 208245380 2 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -1.0885446515682222 [1,2] [0,0] -9 hSpCas9 positive selection 2994711
208248537 208248560 2 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity CTATCACTCCTGATGAGAAGAGG IDH1 ENSG00000138413 0.2827297525608896 [3,3] [3,4] 6 hSpCas9 positive selection 2994712
208248426 208248449 2 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity TTATCTGCAAAAATATCCCCCGG IDH1 ENSG00000138413 0.3599856887179991 [3,3] [3,4] 7 hSpCas9 positive selection 2994713
208248410 208248433 2 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 -0.08781454410441714 [2,2] [1,1] -1 hSpCas9 positive selection 3062568
208245357 208245380 2 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -1.069383508656061 [1,1] [0,0] -9 hSpCas9 positive selection 3062569
208248537 208248560 2 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity CTATCACTCCTGATGAGAAGAGG IDH1 ENSG00000138413 0.4589983743739175 [3,3] [4,3] 7 hSpCas9 positive selection 3062570
208248426 208248449 2 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity TTATCTGCAAAAATATCCCCCGG IDH1 ENSG00000138413 0.012129717534608203 [3,3] [4,1] 0 hSpCas9 positive selection 3062571
208248382 208248405 + 24336571 A375 resistance to PLX after 7 days GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.16855788601860489 [22,24] [25,26] 5 hSpCas9 positive selection 3120298
208248468 208248491 + 24336571 A375 resistance to PLX after 7 days GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 -0.29347078994787634 [4,5] [3,3] -8 hSpCas9 positive selection 3120299
208245316 208245339 + 24336571 A375 resistance to PLX after 7 days TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 0.13026766035928194 [21,20] [23,22] 4 hSpCas9 positive selection 3120300
208248391 208248414 - 24336571 A375 resistance to PLX after 7 days TGGGTAAAACCTATCATCATAGG IDH1 ENSG00000138413 0.11805936672988437 [21,22] [20,27] 4 hSpCas9 positive selection 3120301
208248382 208248405 + 24336571 A375 resistance to PLX after 14 days GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 -0.5197282983564037 [32,31] [9,9] -6 hSpCas9 positive selection 3178091
208248468 208248491 + 24336571 A375 resistance to PLX after 14 days GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.20529567291899542 [3,4] [1,1] 2 hSpCas9 positive selection 3178092
208245316 208245339 + 24336571 A375 resistance to PLX after 14 days TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 0.5209401813538892 [25,17] [11,15] 5 hSpCas9 positive selection 3178093
208248391 208248414 - 24336571 A375 resistance to PLX after 14 days TGGGTAAAACCTATCATCATAGG IDH1 ENSG00000138413 -0.7540792017243707 [28,30] [7,7] -8 hSpCas9 positive selection 3178094
208248382 208248405 + 24336571 A375 viability after 7 days GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.4145382221814349 [18] [22,24] 6 hSpCas9 negative selection 3235884
208248468 208248491 + 24336571 A375 viability after 7 days GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.038786118775228084 [5] [4,5] 0 hSpCas9 negative selection 3235885
208245316 208245339 + 24336571 A375 viability after 7 days TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 0.5701388806270209 [14] [21,20] 8 hSpCas9 negative selection 3235886
208248391 208248414 - 24336571 A375 viability after 7 days TGGGTAAAACCTATCATCATAGG IDH1 ENSG00000138413 0.22196974335069175 [19] [21,22] 3 hSpCas9 negative selection 3235887
208248382 208248405 + 24336571 A375 viability after 14 days GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.8710630066908477 [18] [32,31] 9 hSpCas9 negative selection 3293677
208248468 208248491 + 24336571 A375 viability after 14 days GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 -0.28168024692018223 [5] [3,4] -3 hSpCas9 negative selection 3293678
208245316 208245339 + 24336571 A375 viability after 14 days TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 0.597237746695161 [14] [25,17] 7 hSpCas9 negative selection 3293679
208248391 208248414 - 24336571 A375 viability after 14 days TGGGTAAAACCTATCATCATAGG IDH1 ENSG00000138413 0.6256542581991079 [19] [28,30] 7 hSpCas9 negative selection 3293680
208242000 208242023 2 - 27383988 293T resistance to West Nile virus (flavivirus) TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -1.5075453792902558 [434,434] [0,0] -8 hSpCas9 positive selection 3373679
208245316 208245339 2 + 27383988 293T resistance to West Nile virus (flavivirus) TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -1.2544264423215443 [364,364] [0,0] -8 hSpCas9 positive selection 3373680
208245357 208245380 2 - 27383988 293T resistance to West Nile virus (flavivirus) ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.3425866307412928 [193,193] [0,0] -2 hSpCas9 positive selection 3373681
208248409 208248432 2 + 26780180 HT29 viability (Avana library 4 designs) ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 1.85064435640212 [] [] 7 hSpCas9 negative selection 3432050
208245357 208245380 2 - 26780180 HT29 viability (Avana library 4 designs) ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.472054846935508 [] [] 1 hSpCas9 negative selection 3432051
208248537 208248560 2 - 26780180 HT29 viability (Avana library 4 designs) CTATCACTCCTGATGAGAAGAGG IDH1 ENSG00000138413 0.461632229840829 [] [] 1 hSpCas9 negative selection 3432052
208248426 208248449 2 - 26780180 HT29 viability (Avana library 4 designs) TTATCTGCAAAAATATCCCCCGG IDH1 ENSG00000138413 1.32216696721482 [] [] 5 hSpCas9 negative selection 3432053
208248426 208248449 2 - 26780180 A375 viability (Avana lentiCRISPRv2) TTATCTGCAAAAATATCCCCCGG IDH1 ENSG00000138413 -13.1134276566046 [] [] -8 hSpCas9 negative selection 3518009
208248537 208248560 2 - 26780180 A375 viability (Avana lentiCRISPRv2) CTATCACTCCTGATGAGAAGAGG IDH1 ENSG00000138413 0.265542269465143 [] [] 0 hSpCas9 negative selection 3518010
208245357 208245380 2 - 26780180 A375 viability (Avana lentiCRISPRv2) ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -1.17469332701942 [] [] -1 hSpCas9 negative selection 3518011
208248409 208248432 2 + 26780180 A375 viability (Avana lentiCRISPRv2) ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 5.00432438670832 [] [] 8 hSpCas9 negative selection 3518012
208248382 208248405 2 + 26780180 A375 viability (Avana lentiCRISPRv2) GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 3.4471629092788 [] [] 5 hSpCas9 negative selection 3518013
208248478 208248501 2 + 26780180 A375 viability (Avana lentiCRISPRv2) ATATTTCGTATGGTGCCATTTGG IDH1 ENSG00000138413 1.58266536350288 [] [] 2 hSpCas9 negative selection 3518014
208248426 208248449 2 - 26780180 A375 viability (Avana lentiGuide) TTATCTGCAAAAATATCCCCCGG IDH1 ENSG00000138413 -2.12551469678116 [] [] -4 hSpCas9 negative selection 3626668
208248537 208248560 2 - 26780180 A375 viability (Avana lentiGuide) CTATCACTCCTGATGAGAAGAGG IDH1 ENSG00000138413 -3.4505868055766 [] [] -6 hSpCas9 negative selection 3626669
208245357 208245380 2 - 26780180 A375 viability (Avana lentiGuide) ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 4.58320066127373 [] [] 4 hSpCas9 negative selection 3626670
208248409 208248432 2 + 26780180 A375 viability (Avana lentiGuide) ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 6.28256716635752 [] [] 5 hSpCas9 negative selection 3626671
208248382 208248405 2 + 26780180 A375 viability (Avana lentiGuide) GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.104334684268603 [] [] 0 hSpCas9 negative selection 3626672
208248478 208248501 2 + 26780180 A375 viability (Avana lentiGuide) ATATTTCGTATGGTGCCATTTGG IDH1 ENSG00000138413 -6.50594533572751 [] [] -9 hSpCas9 negative selection 3626673
208248426 208248449 2 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) TTATCTGCAAAAATATCCCCCGG IDH1 ENSG00000138413 -0.9930678758293012 [6] [2,2] -8 hSpCas9 positive selection 3735327
208248537 208248560 2 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CTATCACTCCTGATGAGAAGAGG IDH1 ENSG00000138413 -0.2819467870795732 [5] [4,3] -4 hSpCas9 positive selection 3735328
208245357 208245380 2 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -1.2025854591625698 [4] [0,1] -9 hSpCas9 positive selection 3735329
208248409 208248432 2 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 -0.09597241987418326 [3] [4,2] -1 hSpCas9 positive selection 3735330
208248382 208248405 2 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.30282828765790865 [4] [6,5] 8 hSpCas9 positive selection 3735331
208248478 208248501 2 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) ATATTTCGTATGGTGCCATTTGG IDH1 ENSG00000138413 0.0962407116439859 [6] [5,6] 2 hSpCas9 positive selection 3735332
208248426 208248449 2 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) TTATCTGCAAAAATATCCCCCGG IDH1 ENSG00000138413 0.247507057723343 [5] [5,5] 6 hSpCas9 positive selection 3843934
208248537 208248560 2 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CTATCACTCCTGATGAGAAGAGG IDH1 ENSG00000138413 -0.4305724868546692 [5] [4,1] -5 hSpCas9 positive selection 3843935
208245357 208245380 2 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.2944141853477895 [4] [1,4] -4 hSpCas9 positive selection 3843936
208248409 208248432 2 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 -0.15070565199117253 [4] [2,3] -2 hSpCas9 positive selection 3843937
208248382 208248405 2 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.23566033544115816 [6] [6,6] 6 hSpCas9 positive selection 3843938
208248478 208248501 2 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) ATATTTCGTATGGTGCCATTTGG IDH1 ENSG00000138413 0.33509338365952196 [5] [5,5] 8 hSpCas9 positive selection 3843939
208245357 208245380 2 - 26780180 A375 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 1.67602308296627 [] [] 9 hSpCas9 negative selection 3949916
208242081 208242104 2 - 26780180 A375 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.466575417168841 [] [] 1 hSpCas9 negative selection 3949917
208248382 208248405 2 + 26780180 A375 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.620653116584724 [] [] 2 hSpCas9 negative selection 3949918
208248468 208248491 2 + 26780180 A375 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.267720943648895 [] [] 0 hSpCas9 negative selection 3949919
208245316 208245339 2 + 26780180 A375 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 1.83647340792956 [] [] 9 hSpCas9 negative selection 3949920
208242000 208242023 2 - 26780180 A375 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.609077523108608 [] [] 2 hSpCas9 negative selection 3949921
208245357 208245380 2 - 26780180 HT29 viability (GeCKOv2 library) ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 1.33994332355528 [] [] 6 hSpCas9 negative selection 4057882
208242081 208242104 2 - 26780180 HT29 viability (GeCKOv2 library) GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 1.33956897587425 [] [] 6 hSpCas9 negative selection 4057883
208248382 208248405 2 + 26780180 HT29 viability (GeCKOv2 library) GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.53217726678763 [] [] 1 hSpCas9 negative selection 4057884
208248468 208248491 2 + 26780180 HT29 viability (GeCKOv2 library) GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.490667576732296 [] [] 1 hSpCas9 negative selection 4057885
208245316 208245339 2 + 26780180 HT29 viability (GeCKOv2 library) TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 1.4489500607867 [] [] 7 hSpCas9 negative selection 4057886
208242000 208242023 2 - 26780180 HT29 viability (GeCKOv2 library) TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.77846521895642 [] [] 3 hSpCas9 negative selection 4057887
208248382 208248405 2 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.10190464677801492 [4] [3,3] 2 hSpCas9 positive selection 4143883
208248468 208248491 2 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 -0.41697549830778335 [2] [0,0] -8 hSpCas9 positive selection 4143884
208245316 208245339 2 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 0.291139320396753 [4] [2,3] 7 hSpCas9 positive selection 4143885
208248391 208248414 2 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TGGGTAAAACCTATCATCATAGG IDH1 ENSG00000138413 0.20975176960573388 [4] [3,2] 5 hSpCas9 positive selection 4143886
208248382 208248405 2 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 1.0939555737418312 [4] [4,3,0,6] 8 hSpCas9 positive selection 4207905
208248468 208248491 2 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 -0.354143979369975 [1] [0,0,0,0] -5 hSpCas9 positive selection 4207906
208245316 208245339 2 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.5566250547424678 [3] [0,0,2,0] -7 hSpCas9 positive selection 4207907
208248391 208248414 2 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TGGGTAAAACCTATCATCATAGG IDH1 ENSG00000138413 0.9363704082027053 [4] [0,2,4,4] 6 hSpCas9 positive selection 4207908
208248382 208248405 2 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.20789042956177173 [3] [4,2] 4 hSpCas9 positive selection 4276218
208242081 208242104 2 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.04951765394450652 [2] [1,1] -1 hSpCas9 positive selection 4276219
208248468 208248491 2 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.19469922890225888 [0] [0,0] 4 hSpCas9 positive selection 4276220
208242000 208242023 2 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.1515915758283461 [4] [3,3] 3 hSpCas9 positive selection 4340476
208245316 208245339 2 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.052785560473901205 [4] [3,2] -1 hSpCas9 positive selection 4340477
208245357 208245380 2 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.0936945022614475 [2] [3,1] 2 hSpCas9 positive selection 4340478
208245334 208245356 2 - 27760321 OCIAML3 viability ACCCAAAAGGTGACATACCTGG IDH1 ENSG00000138413 0.6078205880498091 [207,188] [179,309] 7 hSpCas9 negative selection 4408683
208245357 208245379 2 - 27760321 OCIAML3 viability TAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.3977833156047583 [129,112] [133,112] 5 hSpCas9 negative selection 4408684
208248415 208248437 2 - 27760321 OCIAML3 viability ATATCCCCCGGCTTGTGAGTGG IDH1 ENSG00000138413 -0.2061250779183884 [830,735] [406,690] -2 hSpCas9 negative selection 4408685
208248464 208248486 2 - 27760321 OCIAML3 viability CGAAATATTCTGGGTGGCACGG IDH1 ENSG00000138413 0.4993123237738486 [728,537] [594,822] 6 hSpCas9 negative selection 4408686
208251433 208251455 2 + 27760321 OCIAML3 viability TGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.5349163490101769 [579,406] [519,595] 6 hSpCas9 negative selection 4408687
208245334 208245356 2 - 27760321 OCIAML2 viability ACCCAAAAGGTGACATACCTGG IDH1 ENSG00000138413 -0.31053503202250776 [207,188] [112,150] -4 hSpCas9 negative selection 4492146
208245357 208245379 2 - 27760321 OCIAML2 viability TAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.23202471995328944 [129,112] [54,120] -3 hSpCas9 negative selection 4492147
208248415 208248437 2 - 27760321 OCIAML2 viability ATATCCCCCGGCTTGTGAGTGG IDH1 ENSG00000138413 -0.0033213344843655568 [830,735] [525,769] 0 hSpCas9 negative selection 4492148
208248464 208248486 2 - 27760321 OCIAML2 viability CGAAATATTCTGGGTGGCACGG IDH1 ENSG00000138413 0.7281038660414558 [728,537] [772,930] 8 hSpCas9 negative selection 4492149
208251433 208251455 2 + 27760321 OCIAML2 viability TGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.10282288094623979 [579,406] [388,469] 1 hSpCas9 negative selection 4492150
208245334 208245356 2 - 27760321 MV411 viability ACCCAAAAGGTGACATACCTGG IDH1 ENSG00000138413 -0.31300041725321126 [207,188] [74,150] -2 hSpCas9 negative selection 4575609
208245357 208245379 2 - 27760321 MV411 viability TAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.15685057498035393 [129,112] [0,177] -1 hSpCas9 negative selection 4575610
208248415 208248437 2 - 27760321 MV411 viability ATATCCCCCGGCTTGTGAGTGG IDH1 ENSG00000138413 0.011542539712548594 [830,735] [403,694] 0 hSpCas9 negative selection 4575611
208248464 208248486 2 - 27760321 MV411 viability CGAAATATTCTGGGTGGCACGG IDH1 ENSG00000138413 1.6232733757048354 [728,537] [533,2390] 9 hSpCas9 negative selection 4575612
208251433 208251455 2 + 27760321 MV411 viability TGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.9662922770516786 [579,406] [165,1324] 7 hSpCas9 negative selection 4575613
208245334 208245356 2 - 27760321 HL60 viability ACCCAAAAGGTGACATACCTGG IDH1 ENSG00000138413 0.08576250524391438 [207,188] [170,172] 1 hSpCas9 negative selection 4659072
208245357 208245379 2 - 27760321 HL60 viability TAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.27610271982901 [129,112] [106,54] -3 hSpCas9 negative selection 4659073
208248415 208248437 2 - 27760321 HL60 viability ATATCCCCCGGCTTGTGAGTGG IDH1 ENSG00000138413 0.2832354438513208 [830,735] [695,863] 3 hSpCas9 negative selection 4659074
208248464 208248486 2 - 27760321 HL60 viability CGAAATATTCTGGGTGGCACGG IDH1 ENSG00000138413 0.2195718185361777 [728,537] [632,558] 2 hSpCas9 negative selection 4659075
208251433 208251455 2 + 27760321 HL60 viability TGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.00016676478588456556 [579,406] [338,461] 0 hSpCas9 negative selection 4659076
208245334 208245356 2 - 27760321 HT1080 viability ACCCAAAAGGTGACATACCTGG IDH1 ENSG00000138413 2.636757739469388 [188,147] [597,219] 9 hSpCas9 negative selection 4742535
208245357 208245379 2 - 27760321 HT1080 viability TAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.06483066675856808 [112,87] [43,31] 0 hSpCas9 negative selection 4742536
208248415 208248437 2 - 27760321 HT1080 viability ATATCCCCCGGCTTGTGAGTGG IDH1 ENSG00000138413 -0.024019899763855435 [735,574] [421,75] 0 hSpCas9 negative selection 4742537
208248464 208248486 2 - 27760321 HT1080 viability CGAAATATTCTGGGTGGCACGG IDH1 ENSG00000138413 1.64241374804379 [537,419] [747,428] 8 hSpCas9 negative selection 4742538
208251433 208251455 2 + 27760321 HT1080 viability TGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 -0.04641655043468973 [406,317] [241,27] 0 hSpCas9 negative selection 4742539
208245334 208245356 2 - 27760321 HT29 viability after 7 days ACCCAAAAGGTGACATACCTGG IDH1 ENSG00000138413 0.4048393978730901 [188,147] [161,252,422] 6 hSpCas9 negative selection 4825998
208245357 208245379 2 - 27760321 HT29 viability after 7 days TAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.658213713840899 [112,87] [296,134,192] 8 hSpCas9 negative selection 4825999
208248415 208248437 2 - 27760321 HT29 viability after 7 days ATATCCCCCGGCTTGTGAGTGG IDH1 ENSG00000138413 -0.06838545061658097 [735,574] [761,859,782] -1 hSpCas9 negative selection 4826000
208248464 208248486 2 - 27760321 HT29 viability after 7 days CGAAATATTCTGGGTGGCACGG IDH1 ENSG00000138413 0.16899843934034442 [537,419] [775,710,603] 2 hSpCas9 negative selection 4826001
208251433 208251455 2 + 27760321 HT29 viability after 7 days TGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.4607701964610828 [406,317] [642,710,571] 7 hSpCas9 negative selection 4826002
208245334 208245356 2 - 27760321 HT29 viability after 25 days ACCCAAAAGGTGACATACCTGG IDH1 ENSG00000138413 -0.07132783440349422 [188,147] [60,186,323] 0 hSpCas9 negative selection 4909461
208245357 208245379 2 - 27760321 HT29 viability after 25 days TAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.32724059877467404 [112,87] [179,137,107] 3 hSpCas9 negative selection 4909462
208248415 208248437 2 - 27760321 HT29 viability after 25 days ATATCCCCCGGCTTGTGAGTGG IDH1 ENSG00000138413 -0.1017257238103294 [735,574] [515,820,775] -1 hSpCas9 negative selection 4909463
208248464 208248486 2 - 27760321 HT29 viability after 25 days CGAAATATTCTGGGTGGCACGG IDH1 ENSG00000138413 0.5935531042407324 [537,419] [706,850,937] 6 hSpCas9 negative selection 4909464
208251433 208251455 2 + 27760321 HT29 viability after 25 days TGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.46161646852855365 [406,317] [611,560,530] 5 hSpCas9 negative selection 4909465
208245334 208245356 2 - 27760321 HT29 viability after 22 days ACCCAAAAGGTGACATACCTGG IDH1 ENSG00000138413 -0.0851206649129983 [188,147] [128,185,237] -1 hSpCas9 negative selection 4992924
208245357 208245379 2 - 27760321 HT29 viability after 22 days TAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.47244565911301795 [112,87] [111,300,70] 5 hSpCas9 negative selection 4992925
208248415 208248437 2 - 27760321 HT29 viability after 22 days ATATCCCCCGGCTTGTGAGTGG IDH1 ENSG00000138413 -0.09304887649031857 [735,574] [551,743,840] -1 hSpCas9 negative selection 4992926
208248464 208248486 2 - 27760321 HT29 viability after 22 days CGAAATATTCTGGGTGGCACGG IDH1 ENSG00000138413 0.5610136316935603 [537,419] [726,833,892] 6 hSpCas9 negative selection 4992927
208251433 208251455 2 + 27760321 HT29 viability after 22 days TGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.42181784827030266 [406,317] [578,729,372] 4 hSpCas9 negative selection 4992928
208245334 208245356 2 - 27760321 HT29 viability after 19 days ACCCAAAAGGTGACATACCTGG IDH1 ENSG00000138413 0.3400766223677839 [188,147] [103,150,453] 3 hSpCas9 negative selection 5076387
208245357 208245379 2 - 27760321 HT29 viability after 19 days TAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.7277699622094369 [112,87] [190,191,187] 7 hSpCas9 negative selection 5076388
208248415 208248437 2 - 27760321 HT29 viability after 19 days ATATCCCCCGGCTTGTGAGTGG IDH1 ENSG00000138413 0.1508148636552712 [735,574] [998,684,829] 1 hSpCas9 negative selection 5076389
208248464 208248486 2 - 27760321 HT29 viability after 19 days CGAAATATTCTGGGTGGCACGG IDH1 ENSG00000138413 0.44803544271100415 [537,419] [820,674,752] 4 hSpCas9 negative selection 5076390
208251433 208251455 2 + 27760321 HT29 viability after 19 days TGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.6506324625528385 [406,317] [717,771,475] 6 hSpCas9 negative selection 5076391
208245334 208245356 2 - 27760321 HT29 viability after 16 days ACCCAAAAGGTGACATACCTGG IDH1 ENSG00000138413 0.56943178714239 [188,147] [169,279,378] 6 hSpCas9 negative selection 5159850
208245357 208245379 2 - 27760321 HT29 viability after 16 days TAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.5423494870297418 [112,87] [166,219,102] 6 hSpCas9 negative selection 5159851
208248415 208248437 2 - 27760321 HT29 viability after 16 days ATATCCCCCGGCTTGTGAGTGG IDH1 ENSG00000138413 0.03219449306598887 [735,574] [911,753,598] 0 hSpCas9 negative selection 5159852
208248464 208248486 2 - 27760321 HT29 viability after 16 days CGAAATATTCTGGGTGGCACGG IDH1 ENSG00000138413 0.5227849401637311 [537,419] [653,1030,606] 6 hSpCas9 negative selection 5159853
208251433 208251455 2 + 27760321 HT29 viability after 16 days TGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.591577702127051 [406,317] [960,400,509] 7 hSpCas9 negative selection 5159854
208245334 208245356 2 - 27760321 HT29 viability after 13 days ACCCAAAAGGTGACATACCTGG IDH1 ENSG00000138413 0.6968263667699759 [188,147] [347,308,294] 8 hSpCas9 negative selection 5243313
208245357 208245379 2 - 27760321 HT29 viability after 13 days TAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.4962086881181371 [112,87] [67,114,65] -5 hSpCas9 negative selection 5243314
208248415 208248437 2 - 27760321 HT29 viability after 13 days ATATCCCCCGGCTTGTGAGTGG IDH1 ENSG00000138413 0.05525172231382858 [735,574] [908,787,679] 0 hSpCas9 negative selection 5243315
208248464 208248486 2 - 27760321 HT29 viability after 13 days CGAAATATTCTGGGTGGCACGG IDH1 ENSG00000138413 0.43888787245371974 [537,419] [890,795,582] 5 hSpCas9 negative selection 5243316
208251433 208251455 2 + 27760321 HT29 viability after 13 days TGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.36524858762039 [406,317] [386,756,484] 4 hSpCas9 negative selection 5243317
208245334 208245356 2 - 27760321 HT29 viability after 10 days ACCCAAAAGGTGACATACCTGG IDH1 ENSG00000138413 0.7787923169863539 [188,147] [267,241,564] 9 hSpCas9 negative selection 5326776
208245357 208245379 2 - 27760321 HT29 viability after 10 days TAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.7981924636355255 [112,87] [41,136,39] -7 hSpCas9 negative selection 5326777
208248415 208248437 2 - 27760321 HT29 viability after 10 days ATATCCCCCGGCTTGTGAGTGG IDH1 ENSG00000138413 0.25807462811594084 [735,574] [910,943,1077] 3 hSpCas9 negative selection 5326778
208248464 208248486 2 - 27760321 HT29 viability after 10 days CGAAATATTCTGGGTGGCACGG IDH1 ENSG00000138413 0.2390357377222203 [537,419] [714,893,517] 3 hSpCas9 negative selection 5326779
208251433 208251455 2 + 27760321 HT29 viability after 10 days TGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.5194664033725993 [406,317] [731,664,551] 7 hSpCas9 negative selection 5326780
208245334 208245356 2 - 27760321 MOLM13 viability ACCCAAAAGGTGACATACCTGG IDH1 ENSG00000138413 0.38093303960121083 [207,188] [7,262] 2 hSpCas9 negative selection 5410239
208245357 208245379 2 - 27760321 MOLM13 viability TAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.5189160605443202 [129,112] [37,55] -3 hSpCas9 negative selection 5410240
208248415 208248437 2 - 27760321 MOLM13 viability ATATCCCCCGGCTTGTGAGTGG IDH1 ENSG00000138413 -0.015593174065753113 [830,735] [724,190] 0 hSpCas9 negative selection 5410241
208248464 208248486 2 - 27760321 MOLM13 viability CGAAATATTCTGGGTGGCACGG IDH1 ENSG00000138413 -0.1934002120621381 [728,537] [393,237] -1 hSpCas9 negative selection 5410242
208251433 208251455 2 + 27760321 MOLM13 viability TGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 -0.05638316184382346 [579,406] [381,164] 0 hSpCas9 negative selection 5410243
208255065 208255088 2 + 27661255 K562 viability GAAACCCGGGACCACAGGGTAGG IDH1 ENSG00000138413 -0.19183970329832262 [590,673] [450,432] -6 dCas9-KRAB negative selection 5486049
208254685 208254708 2 - 27661255 K562 viability GAGGGAGAAACTGGGCGGTGAGG IDH1 ENSG00000138413 0.10057150927690717 [396,484] [391,362] 3 dCas9-KRAB negative selection 5486050
208254866 208254889 2 - 27661255 K562 viability GCTCTAATTCCGCAGAAGGCAGG IDH1 ENSG00000138413 0.3241159982177244 [0,0] [0,0] 9 dCas9-KRAB negative selection 5486051
208255020 208255043 2 - 27661255 K562 viability GAGGCACTGGGAGTCCGGTTTGG IDH1 ENSG00000138413 -0.06282851612953844 [1203,1065] [1019,741] -2 dCas9-KRAB negative selection 5486052
208248382 208248405 2 + 27260156 BXPC3 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.1725923173444318 [863] [963,808,1156,1175] 4 hSpCas9 negative selection 5548678
208242081 208242104 2 - 27260156 BXPC3 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.43822926316303124 [223] [252,331,373,314] 8 hSpCas9 negative selection 5548679
208248468 208248491 2 + 27260156 BXPC3 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.4026245070944161 [46] [51,60,69,79] 8 hSpCas9 negative selection 5548680
208242000 208242023 2 - 27260156 BXPC3 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.028177941805567208 [1203] [1442,1024,1178,1275] 0 hSpCas9 negative selection 5612936
208245316 208245339 2 + 27260156 BXPC3 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.3385492882649963 [1043] [807,826,791,1049] -6 hSpCas9 negative selection 5612937
208245357 208245380 2 - 27260156 BXPC3 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.06028009719219407 [429] [422,432,439,425] -1 hSpCas9 negative selection 5612938
208248382 208248405 2 + 27260156 A673 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.08235802686934046 [863] [1224,952,1138,1091] 2 hSpCas9 negative selection 5669929
208242081 208242104 2 - 27260156 A673 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.02967806874250911 [223] [300,207,300,247] 0 hSpCas9 negative selection 5669930
208248468 208248491 2 + 27260156 A673 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.22852204125243647 [46] [29,100,51,76] 5 hSpCas9 negative selection 5669931
208242000 208242023 2 - 27260156 A673 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.07382093831963665 [1203] [1579,1307,1228,1402] -2 hSpCas9 negative selection 5734187
208245316 208245339 2 + 27260156 A673 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.26440735629116074 [1043] [1084,1044,1128,909] -6 hSpCas9 negative selection 5734188
208245357 208245380 2 - 27260156 A673 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.6016792660252415 [429] [345,323,325,366] -9 hSpCas9 negative selection 5734189
208248382 208248405 2 + 27260156 A375 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.28304497075234447 [863] [1022,1410,1326,1175] 4 hSpCas9 negative selection 5791180
208242081 208242104 2 - 27260156 A375 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.34167130541923807 [223] [273,361,363,328] 5 hSpCas9 negative selection 5791181
208248468 208248491 2 + 27260156 A375 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 1.3756310792690576 [46] [69,66,202,209] 9 hSpCas9 negative selection 5791182
208242000 208242023 2 - 27260156 A375 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.0032624886070919956 [1203] [1207,1942,1384,1194] 0 hSpCas9 negative selection 5855438
208245316 208245339 2 + 27260156 A375 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 0.18001020357232211 [1043] [1554,1501,1530,996] 2 hSpCas9 negative selection 5855439
208245357 208245380 2 - 27260156 A375 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.7399196219144456 [429] [252,286,298,353] -7 hSpCas9 negative selection 5855440
208248382 208248405 2 + 27260156 COLO741 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 -0.051889439773679435 [863] [1231,1100,886] -1 hSpCas9 negative selection 5912431
208242081 208242104 2 - 27260156 COLO741 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.029099918005363046 [223] [252,323,294] 0 hSpCas9 negative selection 5912432
208248468 208248491 2 + 27260156 COLO741 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.1841169707072261 [46] [70,54,77] 4 hSpCas9 negative selection 5912433
208242000 208242023 2 - 27260156 COLO741 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.17790104355565117 [1203] [1749,2010,1476] 4 hSpCas9 negative selection 5976689
208245316 208245339 2 + 27260156 COLO741 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.20336850999495304 [1043] [1131,1321,1026] -4 hSpCas9 negative selection 5976690
208245357 208245380 2 - 27260156 COLO741 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.5782991896090833 [429] [455,336,320] -8 hSpCas9 negative selection 5976691
208248382 208248405 2 + 27260156 CAL120 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.3058330739385876 [863] [1268,1630,1081] 4 hSpCas9 negative selection 6033682
208242081 208242104 2 - 27260156 CAL120 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.12885030704483014 [223] [306,237,227] -2 hSpCas9 negative selection 6033683
208248468 208248491 2 + 27260156 CAL120 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.6646734919536987 [46] [144,105,35] 8 hSpCas9 negative selection 6033684
208242000 208242023 2 - 27260156 CAL120 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.040975394084883154 [1203] [1643,1452,1541] 0 hSpCas9 negative selection 6097940
208245316 208245339 2 + 27260156 CAL120 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 0.013210111207321074 [1043] [1433,1137,1377] 0 hSpCas9 negative selection 6097941
208245357 208245380 2 - 27260156 CAL120 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.7498332438477183 [429] [377,296,288] -8 hSpCas9 negative selection 6097942
208248382 208248405 2 + 27260156 CADOES1 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.049005823105076396 [863] [772,654,1041,855] 0 hSpCas9 negative selection 6154933
208242081 208242104 2 - 27260156 CADOES1 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.04856645102728052 [223] [207,200,207,245] 0 hSpCas9 negative selection 6154934
208248468 208248491 2 + 27260156 CADOES1 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.40343825202099426 [46] [49,60,18,102] 6 hSpCas9 negative selection 6154935
208242000 208242023 2 - 27260156 CADOES1 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.015127996013687195 [1203] [1010,1171,983,1271] 0 hSpCas9 negative selection 6219191
208245316 208245339 2 + 27260156 CADOES1 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.1263943033318058 [1043] [801,890,907,959] -2 hSpCas9 negative selection 6219192
208245357 208245380 2 - 27260156 CADOES1 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.818734966341877 [429] [255,207,236,204] -8 hSpCas9 negative selection 6219193
208248382 208248405 2 + 27260156 EWS502 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.3331771116245902 [863] [908,1090,1294,1360] 6 hSpCas9 negative selection 6276184
208242081 208242104 2 - 27260156 EWS502 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.29862862897474884 [223] [301,268,286,308] 5 hSpCas9 negative selection 6276185
208248468 208248491 2 + 27260156 EWS502 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.5236926840171137 [46] [22,52,156,59] 8 hSpCas9 negative selection 6276186
208242000 208242023 2 - 27260156 EWS502 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.09996841483880292 [1203] [1156,1486,1628,1200] 1 hSpCas9 negative selection 6340442
208245316 208245339 2 + 27260156 EWS502 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.28303459159169075 [1043] [884,850,849,1060] -5 hSpCas9 negative selection 6340443
208245357 208245380 2 - 27260156 EWS502 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.7629123606142766 [429] [179,250,347,308] -8 hSpCas9 negative selection 6340444
208248382 208248405 2 + 27260156 EW8 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.3692775134326617 [863] [1133,884,729,920] 6 hSpCas9 negative selection 6397435
208242081 208242104 2 - 27260156 EW8 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.01712483371120177 [223] [176,188,150,221] 0 hSpCas9 negative selection 6397436
208248468 208248491 2 + 27260156 EW8 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.44188602881447636 [46] [31,46,36,90] 7 hSpCas9 negative selection 6397437
208242000 208242023 2 - 27260156 EW8 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.03911045761955889 [1203] [1201,962,603,1112] 0 hSpCas9 negative selection 6461693
208245316 208245339 2 + 27260156 EW8 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.2634165012664822 [1043] [790,578,807,630] -5 hSpCas9 negative selection 6461694
208245357 208245380 2 - 27260156 EW8 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.5775457742932004 [429] [286,210,198,247] -8 hSpCas9 negative selection 6461695
208248382 208248405 2 + 27260156 CORL105 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.25822112373470907 [863] [1373,974,1475,1065] 5 hSpCas9 negative selection 6518686
208242081 208242104 2 - 27260156 CORL105 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.3141602306080108 [223] [534,237,310,226] 6 hSpCas9 negative selection 6518687
208248468 208248491 2 + 27260156 CORL105 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.6887045622371204 [46] [80,43,137,99] 9 hSpCas9 negative selection 6518688
208242000 208242023 2 - 27260156 CORL105 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.07099186016080172 [1203] [1832,1176,1704,1260] 1 hSpCas9 negative selection 6582944
208245316 208245339 2 + 27260156 CORL105 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.13635942083135677 [1043] [1071,1052,1587,809] -3 hSpCas9 negative selection 6582945
208245357 208245380 2 - 27260156 CORL105 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.44253227457234523 [429] [468,314,312,379] -7 hSpCas9 negative selection 6582946
208248382 208248405 2 + 27260156 HS294T viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.18911899642889185 [863] [420,339,415,334] 2 hSpCas9 negative selection 6639937
208242081 208242104 2 - 27260156 HS294T viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.17716808511069337 [223] [61,89,145,96] 2 hSpCas9 negative selection 6639938
208248468 208248491 2 + 27260156 HS294T viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.380477685554673 [46] [15,28,26,22] 5 hSpCas9 negative selection 6639939
208242000 208242023 2 - 27260156 HS294T viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.46804258783824626 [1203] [298,330,296,438] -6 hSpCas9 negative selection 6704195
208245316 208245339 2 + 27260156 HS294T viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.330877573088056 [1043] [184,400,366,343] -5 hSpCas9 negative selection 6704196
208245357 208245380 2 - 27260156 HS294T viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.21770680696464592 [429] [184,64,156,166] -3 hSpCas9 negative selection 6704197
208248382 208248405 2 + 27260156 HCC44 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.34367382062443974 [863] [974,1245,1703,1084] 5 hSpCas9 negative selection 6761188
208242081 208242104 2 - 27260156 HCC44 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.22111100375470172 [223] [354,279,326,231] 3 hSpCas9 negative selection 6761189
208248468 208248491 2 + 27260156 HCC44 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.45672216498742824 [46] [20,140,18,85] 7 hSpCas9 negative selection 6761190
208242000 208242023 2 - 27260156 HCC44 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.08439289896446378 [1203] [1288,1165,1974,1449] 1 hSpCas9 negative selection 6825446
208245316 208245339 2 + 27260156 HCC44 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.04732861590062254 [1043] [999,1042,1474,1102] -1 hSpCas9 negative selection 6825447
208245357 208245380 2 - 27260156 HCC44 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.7312342990635372 [429] [198,216,557,244] -8 hSpCas9 negative selection 6825448
208248382 208248405 2 + 27260156 G402 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.3092382040665079 [863] [1317,1653,1388,900] 4 hSpCas9 negative selection 6882439
208242081 208242104 2 - 27260156 G402 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.4234028723908082 [223] [526,236,467,253] 5 hSpCas9 negative selection 6882440
208248468 208248491 2 + 27260156 G402 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 -2.0465839307115252 [46] [29,13,3,9] -9 hSpCas9 negative selection 6882441
208242000 208242023 2 - 27260156 G402 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.20111865309142152 [1203] [1142,1147,1514,1273] -3 hSpCas9 negative selection 6946697
208245316 208245339 2 + 27260156 G402 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.5076507463002097 [1043] [1054,734,1052,757] -6 hSpCas9 negative selection 6946698
208245357 208245380 2 - 27260156 G402 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.993801609911978 [429] [301,239,228,284] -8 hSpCas9 negative selection 6946699
208248382 208248405 2 + 27260156 L33 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.14923132452444732 [863] [738,405,630,1102] 3 hSpCas9 negative selection 7003690
208242081 208242104 2 - 27260156 L33 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.04069985944794219 [223] [259,107,82,213] -1 hSpCas9 negative selection 7003691
208248468 208248491 2 + 27260156 L33 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.4632496698403066 [46] [95,27,28,47] 8 hSpCas9 negative selection 7003692
208242000 208242023 2 - 27260156 L33 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.23840149018128742 [1203] [1174,392,493,1155] -5 hSpCas9 negative selection 7067948
208245316 208245339 2 + 27260156 L33 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.15296651413600004 [1043] [891,362,609,1007] -3 hSpCas9 negative selection 7067949
208245357 208245380 2 - 27260156 L33 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.23579170987426182 [429] [420,113,248,363] -5 hSpCas9 negative selection 7067950
208248382 208248405 2 + 27260156 K562 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.030529688175074066 [863] [917,482,784,921] 0 hSpCas9 negative selection 7124941
208242081 208242104 2 - 27260156 K562 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.27395719556966913 [223] [367,206,284,122] 3 hSpCas9 negative selection 7124942
208248468 208248491 2 + 27260156 K562 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 -0.3550085056723109 [46] [61,18,8,40] -4 hSpCas9 negative selection 7124943
208242000 208242023 2 - 27260156 K562 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.40275862972384924 [1203] [1232,1690,1240,1471] 5 hSpCas9 negative selection 7189199
208245316 208245339 2 + 27260156 K562 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 0.13402905463170378 [1043] [1068,943,1317,761] 1 hSpCas9 negative selection 7189200
208245357 208245380 2 - 27260156 K562 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.21324825149017698 [429] [488,575,151,145] -3 hSpCas9 negative selection 7189201
208248382 208248405 2 + 27260156 HT29 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.13887648999207813 [863] [1446,1356,895,978] 2 hSpCas9 negative selection 7246192
208242081 208242104 2 - 27260156 HT29 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.2242679807406872 [223] [451,297,222,306] 4 hSpCas9 negative selection 7246193
208248468 208248491 2 + 27260156 HT29 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.6028722917466709 [46] [137,115,39,61] 9 hSpCas9 negative selection 7246194
208242000 208242023 2 - 27260156 HT29 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.011720191710322458 [1203] [1428,1971,1279,1190] 0 hSpCas9 negative selection 7310450
208245316 208245339 2 + 27260156 HT29 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.084772345664472 [1043] [1244,1398,1011,1148] -2 hSpCas9 negative selection 7310451
208245357 208245380 2 - 27260156 HT29 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.6862279803399686 [429] [380,299,398,230] -8 hSpCas9 negative selection 7310452
208248382 208248405 2 + 27260156 MHHES1 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 -0.1792716958224555 [863] [905,689,892,905] -3 hSpCas9 negative selection 7367443
208242081 208242104 2 - 27260156 MHHES1 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.42614039680486604 [223] [270,250,111,139] -7 hSpCas9 negative selection 7367444
208248468 208248491 2 + 27260156 MHHES1 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.8111900470822011 [46] [57,169,17,119] 9 hSpCas9 negative selection 7367445
208242000 208242023 2 - 27260156 MHHES1 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.40682168998410617 [1203] [1040,1092,1161,827] -6 hSpCas9 negative selection 7431701
208245316 208245339 2 + 27260156 MHHES1 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.10753128607447415 [1043] [1039,1419,913,1010] -2 hSpCas9 negative selection 7431702
208245357 208245380 2 - 27260156 MHHES1 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.6190965100121267 [429] [425,219,308,304] -8 hSpCas9 negative selection 7431703
208248382 208248405 2 + 27260156 MEWO viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.31209054088575783 [863] [1131,856,1046] 6 hSpCas9 negative selection 7488694
208242081 208242104 2 - 27260156 MEWO viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.09260099323180515 [223] [313,195,177] 2 hSpCas9 negative selection 7488695
208248468 208248491 2 + 27260156 MEWO viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.26356036432654095 [46] [86,46,30] 6 hSpCas9 negative selection 7488696
208242000 208242023 2 - 27260156 MEWO viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.014204961809941796 [1203] [1287,1183,906] 0 hSpCas9 negative selection 7552952
208245316 208245339 2 + 27260156 MEWO viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.17401211249465287 [1043] [952,854,805] -4 hSpCas9 negative selection 7552953
208245357 208245380 2 - 27260156 MEWO viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.8055384215958306 [429] [274,259,163] -9 hSpCas9 negative selection 7552954
208248382 208248405 2 + 27260156 LNCAPCLONEFGC viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.14159418217593778 [863] [751,931,960,819] 2 hSpCas9 negative selection 7609945
208242081 208242104 2 - 27260156 LNCAPCLONEFGC viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.39356427251493786 [223] [241,272,292,261] 6 hSpCas9 negative selection 7609946
208248468 208248491 2 + 27260156 LNCAPCLONEFGC viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.09989497108359613 [46] [48,17,43,72] 1 hSpCas9 negative selection 7609947
208242000 208242023 2 - 27260156 LNCAPCLONEFGC viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.0902813782277494 [1203] [1081,915,1082,1030] -1 hSpCas9 negative selection 7674203
208245316 208245339 2 + 27260156 LNCAPCLONEFGC viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.24461273443557074 [1043] [717,775,1098,646] -4 hSpCas9 negative selection 7674204
208245357 208245380 2 - 27260156 LNCAPCLONEFGC viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.6666901616688241 [429] [180,259,348,206] -7 hSpCas9 negative selection 7674205
208248382 208248405 2 + 27260156 PANC0327 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.2788219801140831 [863] [950,851,912,1019] 4 hSpCas9 negative selection 7731196
208242081 208242104 2 - 27260156 PANC0327 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.6161206266913684 [223] [414,217,257,348] 8 hSpCas9 negative selection 7731197
208248468 208248491 2 + 27260156 PANC0327 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.9813982719995886 [46] [145,72,13,102] 9 hSpCas9 negative selection 7731198
208242000 208242023 2 - 27260156 PANC0327 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.1441618069892887 [1203] [1472,576,1024,887] -2 hSpCas9 negative selection 7795454
208245316 208245339 2 + 27260156 PANC0327 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.16073642822474354 [1043] [1229,951,581,570] -2 hSpCas9 negative selection 7795455
208245357 208245380 2 - 27260156 PANC0327 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.33337817425423577 [429] [259,705,559,351] 5 hSpCas9 negative selection 7795456
208248382 208248405 2 + 27260156 NCIH2009 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.0012681988931391164 [863] [1254,1252,1122] 0 hSpCas9 negative selection 7852447
208242081 208242104 2 - 27260156 NCIH2009 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.005496125070233671 [223] [314,319,306] 0 hSpCas9 negative selection 7852448
208248468 208248491 2 + 27260156 NCIH2009 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 1.0244253271852366 [46] [254,105,63] 9 hSpCas9 negative selection 7852449
208242000 208242023 2 - 27260156 NCIH2009 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.18013307787471278 [1203] [1791,1340,1381] -2 hSpCas9 negative selection 7916705
208245316 208245339 2 + 27260156 NCIH2009 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.255255871935697 [1043] [1311,945,1428] -3 hSpCas9 negative selection 7916706
208245357 208245380 2 - 27260156 NCIH2009 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.6266518598289569 [429] [525,318,349] -7 hSpCas9 negative selection 7916707
208248382 208248405 2 + 27260156 NCIH1373 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 -0.08647479695250815 [863] [1053,887,765,253] -1 hSpCas9 negative selection 7973698
208242081 208242104 2 - 27260156 NCIH1373 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.02687785037461965 [223] [472,211,118,57] 0 hSpCas9 negative selection 7973699
208248468 208248491 2 + 27260156 NCIH1373 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 -0.9585851560319392 [46] [16,7,3,21] -7 hSpCas9 negative selection 7973700
208242000 208242023 2 - 27260156 NCIH1373 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.3431344569591539 [1203] [1102,920,825,380] -3 hSpCas9 negative selection 8037956
208245316 208245339 2 + 27260156 NCIH1373 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 0.18523389907977816 [1043] [1782,1570,1043,247] 1 hSpCas9 negative selection 8037957
208245357 208245380 2 - 27260156 NCIH1373 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.6898631724316954 [429] [149,242,268,138] -6 hSpCas9 negative selection 8037958
208248382 208248405 2 + 27260156 PATU8902 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 -0.057768640676746585 [863] [1095,1393,875,1345] 0 hSpCas9 negative selection 8094949
208242081 208242104 2 - 27260156 PATU8902 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.4920393720560462 [223] [371,664,183,619] 5 hSpCas9 negative selection 8094950
208248468 208248491 2 + 27260156 PATU8902 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 -1.5801384284502578 [46] [30,27,19,6] -8 hSpCas9 negative selection 8094951
208242000 208242023 2 - 27260156 PATU8902 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.13244668138903237 [1203] [1282,1496,1713,1572] -1 hSpCas9 negative selection 8159207
208245316 208245339 2 + 27260156 PATU8902 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 0.21894232750088505 [1043] [2919,1190,955,1884] 2 hSpCas9 negative selection 8159208
208245357 208245380 2 - 27260156 PATU8902 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.009275441264227552 [429] [440,429,874,552] 0 hSpCas9 negative selection 8159209
208248382 208248405 2 + 27260156 PANC1 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.1317318446811192 [863] [767,1005,716,790] 2 hSpCas9 negative selection 8216200
208242081 208242104 2 - 27260156 PANC1 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.34713176612345786 [223] [277,331,148,233] 5 hSpCas9 negative selection 8216201
208248468 208248491 2 + 27260156 PANC1 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.14275576338581564 [46] [28,28,39,71] 2 hSpCas9 negative selection 8216202
208242000 208242023 2 - 27260156 PANC1 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.03075582581962144 [1203] [1182,1126,934,835] 0 hSpCas9 negative selection 8280458
208245316 208245339 2 + 27260156 PANC1 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.15703610027519022 [1043] [625,1001,782,831] -3 hSpCas9 negative selection 8280459
208245357 208245380 2 - 27260156 PANC1 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.15630676195356205 [429] [265,369,456,250] -3 hSpCas9 negative selection 8280460
208248382 208248405 2 + 27260156 PANC0813 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.20412860947700595 [863] [1401,1013,1179,1103] 3 hSpCas9 negative selection 8337451
208242081 208242104 2 - 27260156 PANC0813 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.10467198350214435 [223] [244,211,231,286] -2 hSpCas9 negative selection 8337452
208248468 208248491 2 + 27260156 PANC0813 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 1.0468089750175822 [46] [40,70,174,159] 9 hSpCas9 negative selection 8337453
208242000 208242023 2 - 27260156 PANC0813 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.1453437989130848 [1203] [1464,1046,1331,1285] -2 hSpCas9 negative selection 8401709
208245316 208245339 2 + 27260156 PANC0813 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.2153131748951943 [1043] [1223,970,1352,711] -3 hSpCas9 negative selection 8401710
208245357 208245380 2 - 27260156 PANC0813 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.1211231242196378 [429] [388,605,415,439] -2 hSpCas9 negative selection 8401711
208248382 208248405 2 + 27260156 RDES viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 -0.006214938411411408 [863] [684,933,1180,1247] 0 hSpCas9 negative selection 8458702
208242081 208242104 2 - 27260156 RDES viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.5054803724680722 [223] [295,297,412,486] 7 hSpCas9 negative selection 8458703
208248468 208248491 2 + 27260156 RDES viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 -0.05552513813505611 [46] [39,42,67,60] -1 hSpCas9 negative selection 8458704
208242000 208242023 2 - 27260156 RDES viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.04199382898818693 [1203] [1092,1209,1443,1720] 0 hSpCas9 negative selection 8522960
208245316 208245339 2 + 27260156 RDES viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.06284570267670286 [1043] [1003,1024,1041,1598] -1 hSpCas9 negative selection 8522961
208245357 208245380 2 - 27260156 RDES viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.6179080511678936 [429] [328,297,327,323] -8 hSpCas9 negative selection 8522962
208248382 208248405 2 + 27260156 PC3 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.03168164980848909 [863] [567,794,1597,894] 0 hSpCas9 negative selection 8579953
208242081 208242104 2 - 27260156 PC3 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.15247819974117394 [223] [201,209,487,174] 3 hSpCas9 negative selection 8579954
208248468 208248491 2 + 27260156 PC3 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 -0.19953523828181785 [46] [15,60,19,65] -4 hSpCas9 negative selection 8579955
208242000 208242023 2 - 27260156 PC3 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.176082859060392 [1203] [767,805,1607,1317] -4 hSpCas9 negative selection 8644211
208245316 208245339 2 + 27260156 PC3 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.27971841399511543 [1043] [419,989,1300,1012] -6 hSpCas9 negative selection 8644212
208245357 208245380 2 - 27260156 PC3 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.4705089898570627 [429] [238,256,484,322] -8 hSpCas9 negative selection 8644213
208248382 208248405 2 + 27260156 PATU8988T viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.17513373991169623 [863] [562,1088,1182,945] 3 hSpCas9 negative selection 8701204
208242081 208242104 2 - 27260156 PATU8988T viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.43183170988080477 [223] [261,574,160,189] 7 hSpCas9 negative selection 8701205
208248468 208248491 2 + 27260156 PATU8988T viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 -0.22975015164627388 [46] [61,53,29,7] -4 hSpCas9 negative selection 8701206
208242000 208242023 2 - 27260156 PATU8988T viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 0.0484064199871741 [1203] [1287,1341,1113,1071] 0 hSpCas9 negative selection 8765462
208245316 208245339 2 + 27260156 PATU8988T viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.41806127870147436 [1043] [761,959,601,713] -6 hSpCas9 negative selection 8765463
208245357 208245380 2 - 27260156 PATU8988T viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.05387566984251274 [429] [351,613,305,345] -1 hSpCas9 negative selection 8765464
208248382 208248405 2 + 27260156 T47D viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.1744711001651621 [863] [1166,1171,1034,1168] 4 hSpCas9 negative selection 8822455
208242081 208242104 2 - 27260156 T47D viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.32248976958013853 [223] [271,303,335,396] 6 hSpCas9 negative selection 8822456
208248468 208248491 2 + 27260156 T47D viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.562984261419897 [46] [88,96,66,68] 9 hSpCas9 negative selection 8822457
208242000 208242023 2 - 27260156 T47D viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.06252031672360414 [1203] [1264,1295,1285,1535] -1 hSpCas9 negative selection 8886713
208245316 208245339 2 + 27260156 T47D viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.20984990579783802 [1043] [1067,996,1056,1089] -4 hSpCas9 negative selection 8886714
208245357 208245380 2 - 27260156 T47D viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.5612411725182622 [429] [306,299,352,402] -8 hSpCas9 negative selection 8886715
208248382 208248405 2 + 27260156 SU8686 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.07870042102807862 [863] [689,957,883,1133] 1 hSpCas9 negative selection 8943706
208242081 208242104 2 - 27260156 SU8686 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.07131383949024339 [223] [197,191,297,258] 1 hSpCas9 negative selection 8943707
208248468 208248491 2 + 27260156 SU8686 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 1.0149921403032796 [46] [42,59,79,223] 9 hSpCas9 negative selection 8943708
208242000 208242023 2 - 27260156 SU8686 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.27104187430797566 [1203] [859,985,969,1178] -4 hSpCas9 negative selection 9007964
208245316 208245339 2 + 27260156 SU8686 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.24099954876826468 [1043] [750,741,928,1152] -4 hSpCas9 negative selection 9007965
208245357 208245380 2 - 27260156 SU8686 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.0004046665503529556 [429] [406,389,425,496] 0 hSpCas9 negative selection 9007966
208248382 208248405 2 + 27260156 SKES1 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 -0.04326741382094801 [863] [915,1018,789,665] -1 hSpCas9 negative selection 9064957
208242081 208242104 2 - 27260156 SKES1 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.5044613333029614 [223] [608,234,202,256] 8 hSpCas9 negative selection 9064958
208248468 208248491 2 + 27260156 SKES1 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.9602217769450969 [46] [55,158,96,58] 9 hSpCas9 negative selection 9064959
208242000 208242023 2 - 27260156 SKES1 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.1014401030857297 [1203] [1059,1220,1302,908] -2 hSpCas9 negative selection 9129215
208245316 208245339 2 + 27260156 SKES1 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.21054179416112329 [1043] [1134,997,950,587] -4 hSpCas9 negative selection 9129216
208245357 208245380 2 - 27260156 SKES1 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.6081890538955178 [429] [329,338,212,257] -8 hSpCas9 negative selection 9129217
208248382 208248405 2 + 27260156 TOV112D viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 0.16536476892674068 [863] [815,1372,1125,659] 3 hSpCas9 negative selection 9186208
208242081 208242104 2 - 27260156 TOV112D viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.32498418350106517 [223] [200,186,156,174] -6 hSpCas9 negative selection 9186209
208248468 208248491 2 + 27260156 TOV112D viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.5308832919886712 [46] [63,169,41,21] 8 hSpCas9 negative selection 9186210
208242000 208242023 2 - 27260156 TOV112D viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.2574755945856033 [1203] [790,1233,873,1166] -5 hSpCas9 negative selection 9250466
208245316 208245339 2 + 27260156 TOV112D viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.1354199828365814 [1043] [842,1263,1039,732] -3 hSpCas9 negative selection 9250467
208245357 208245380 2 - 27260156 TOV112D viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.7271832634233489 [429] [256,442,235,151] -9 hSpCas9 negative selection 9250468
208248382 208248405 2 + 27260156 TC71 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 -0.054669698791966814 [863] [947,938,758,925] -1 hSpCas9 negative selection 9307459
208242081 208242104 2 - 27260156 TC71 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.08124212691104149 [223] [286,221,224,168] -2 hSpCas9 negative selection 9307460
208248468 208248491 2 + 27260156 TC71 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.9480503430614164 [46] [102,102,105,74] 9 hSpCas9 negative selection 9307461
208242000 208242023 2 - 27260156 TC71 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.2548047486256624 [1203] [978,1046,1051,1262] -6 hSpCas9 negative selection 9371717
208245316 208245339 2 + 27260156 TC71 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.24228970384137827 [1043] [896,911,984,992] -6 hSpCas9 negative selection 9371718
208245357 208245380 2 - 27260156 TC71 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.6547443443478269 [429] [329,258,222,364] -9 hSpCas9 negative selection 9371719
208248382 208248405 2 + 27260156 TC32 viability GCATGACGACCTATGATGATAGG IDH1 ENSG00000138413 -0.08405361857243687 [863] [728,497,1086,873] -1 hSpCas9 negative selection 9428710
208242081 208242104 2 - 27260156 TC32 viability GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.38444174507024154 [223] [198,352,392,126] 6 hSpCas9 negative selection 9428711
208248468 208248491 2 + 27260156 TC32 viability GCCACCCAGAATATTTCGTATGG IDH1 ENSG00000138413 0.05175465571173943 [46] [31,52,27,63] 1 hSpCas9 negative selection 9428712
208242000 208242023 2 - 27260156 TC32 viability TGACGTGCAGTCGGACTCTGTGG IDH1 ENSG00000138413 -0.16374075073784078 [1203] [1030,550,1442,1216] -3 hSpCas9 negative selection 9492968
208245316 208245339 2 + 27260156 TC32 viability TACCTTCAAAGTTATGTACCAGG IDH1 ENSG00000138413 -0.0903484779138235 [1043] [857,861,1098,865] -1 hSpCas9 negative selection 9492969
208245357 208245380 2 - 27260156 TC32 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.6375335383091848 [429] [190,255,285,306] -8 hSpCas9 negative selection 9492970
208242081 208242104 2 - 27869803 HPAFII viability after 27 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.8073033447363649 [332] [193,399,NaN] 6 hSpCas9 negative selection 9573210
208242081 208242104 2 - 27869803 HPAFII viability after 15 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.5518447550208123 [332] [470,557,NaN] 6 hSpCas9 negative selection 9655659
208242081 208242104 2 - 27869803 ASPC1 viability after 36 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 -0.14641277428149638 [801] [438,268,106] -1 hSpCas9 negative selection 9738108
208242081 208242104 2 - 27869803 PATU8988S viability after 35 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.618234623090208 [669] [504,322,NaN] 6 hSpCas9 negative selection 9820557
208242081 208242104 2 - 27869803 PATU8988S viability after 31 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.5631148308597567 [669] [366,429,NaN] 6 hSpCas9 negative selection 9903006
208242081 208242104 2 - 27869803 HPAFII viability after 35 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 1.1459560196015364 [332] [246,514,NaN] 7 hSpCas9 negative selection 9985455
208242081 208242104 2 - 27869803 HPAFII viability after 31 days GCATAGGCTCATCGACGACATGG IDH1 ENSG00000138413 0.7338355261243432 [332] [149,485,NaN] 5 hSpCas9 negative selection 10067904
208245357 208245380 2 - 28162770 P31FUJ viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.43273977492313076 [84] [73] -4 hSpCas9 negative selection 10172526
208243510 208243533 2 - 28162770 P31FUJ viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 -0.2328022044143786 [134] [134] -2 hSpCas9 negative selection 10172527
208242078 208242101 2 - 28162770 P31FUJ viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 -0.07825242885898209 [282] [314] -1 hSpCas9 negative selection 10172528
208239925 208239948 2 - 28162770 P31FUJ viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.5023457191217271 [310] [257] -4 hSpCas9 negative selection 10172529
208251432 208251455 2 + 28162770 P31FUJ viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.7939978549293366 [399] [814] 8 hSpCas9 negative selection 10172530
208248409 208248432 2 + 28162770 P31FUJ viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 0.08549950806703446 [238] [297] 0 hSpCas9 negative selection 10172531
208242053 208242076 2 - 28162770 P31FUJ viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 -0.8177647051355348 [47] [31] -6 hSpCas9 negative selection 10172532
208239909 208239932 2 + 28162770 P31FUJ viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 0.15222272579802554 [339] [443] 1 hSpCas9 negative selection 10172533
208239862 208239885 2 - 28162770 P31FUJ viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 0.04283223819904869 [778] [942] 0 hSpCas9 negative selection 10172534
208243582 208243605 2 - 28162770 P31FUJ viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.7450521547056645 [557] [1098] 8 hSpCas9 negative selection 10172535
208245357 208245380 2 - 28162770 TF1 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 NaN [NaN] [29] 1 hSpCas9 negative selection 10341892
208243510 208243533 2 - 28162770 TF1 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 NaN [NaN] [33] 1 hSpCas9 negative selection 10341893
208242078 208242101 2 - 28162770 TF1 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 NaN [NaN] [260] 1 hSpCas9 negative selection 10341894
208239925 208239948 2 - 28162770 TF1 viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 NaN [NaN] [249] 1 hSpCas9 negative selection 10341895
208251432 208251455 2 + 28162770 TF1 viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 NaN [NaN] [504] 1 hSpCas9 negative selection 10341896
208248409 208248432 2 + 28162770 TF1 viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 NaN [NaN] [83] 1 hSpCas9 negative selection 10341897
208242053 208242076 2 - 28162770 TF1 viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 NaN [NaN] [50] 1 hSpCas9 negative selection 10341898
208239909 208239932 2 + 28162770 TF1 viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 NaN [NaN] [356] 1 hSpCas9 negative selection 10341899
208239862 208239885 2 - 28162770 TF1 viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 NaN [NaN] [757] 1 hSpCas9 negative selection 10341900
208243582 208243605 2 - 28162770 TF1 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 NaN [NaN] [622] 1 hSpCas9 negative selection 10341901
208245357 208245380 2 - 28162770 SKM1 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.1779983019779945 [24] [49] 1 hSpCas9 negative selection 10511258
208243510 208243533 2 - 28162770 SKM1 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 0.15103125437772513 [26] [52] 1 hSpCas9 negative selection 10511259
208242078 208242101 2 - 28162770 SKM1 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 0.05442361685946201 [66] [122] 0 hSpCas9 negative selection 10511260
208239925 208239948 2 - 28162770 SKM1 viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.12507076565805186 [94] [153] -1 hSpCas9 negative selection 10511261
208251432 208251455 2 + 28162770 SKM1 viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.3394617246721108 [113] [254] 3 hSpCas9 negative selection 10511262
208248409 208248432 2 + 28162770 SKM1 viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 -0.14850252269919212 [78] [125] -1 hSpCas9 negative selection 10511263
208242053 208242076 2 - 28162770 SKM1 viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 0.08488889758651319 [15] [29] 0 hSpCas9 negative selection 10511264
208239909 208239932 2 + 28162770 SKM1 viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 -0.29475469515713654 [67] [97] -2 hSpCas9 negative selection 10511265
208239862 208239885 2 - 28162770 SKM1 viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 -0.4123574575133804 [200] [266] -3 hSpCas9 negative selection 10511266
208243582 208243605 2 - 28162770 SKM1 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.9493739269300319 [115] [395] 8 hSpCas9 negative selection 10511267
208245357 208245380 2 - 28162770 SKM1 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.1779983019779945 [24] [49] 1 hSpCas9 negative selection 10680624
208243510 208243533 2 - 28162770 SKM1 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 0.15103125437772513 [26] [52] 1 hSpCas9 negative selection 10680625
208242078 208242101 2 - 28162770 SKM1 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 0.05442361685946201 [66] [122] 0 hSpCas9 negative selection 10680626
208239925 208239948 2 - 28162770 SKM1 viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.12507076565805186 [94] [153] -1 hSpCas9 negative selection 10680627
208251432 208251455 2 + 28162770 SKM1 viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.3394617246721108 [113] [254] 3 hSpCas9 negative selection 10680628
208248409 208248432 2 + 28162770 SKM1 viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 -0.14850252269919212 [78] [125] -1 hSpCas9 negative selection 10680629
208242053 208242076 2 - 28162770 SKM1 viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 0.08488889758651319 [15] [29] 0 hSpCas9 negative selection 10680630
208239909 208239932 2 + 28162770 SKM1 viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 -0.29475469515713654 [67] [97] -2 hSpCas9 negative selection 10680631
208239862 208239885 2 - 28162770 SKM1 viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 -0.4123574575133804 [200] [266] -3 hSpCas9 negative selection 10680632
208243582 208243605 2 - 28162770 SKM1 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.9493739269300319 [115] [395] 8 hSpCas9 negative selection 10680633
208245357 208245380 2 - 28162770 PL21 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.9697853869529922 [98] [21] -6 hSpCas9 negative selection 10849990
208243510 208243533 2 - 28162770 PL21 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 0.1456918304669439 [53] [25] 1 hSpCas9 negative selection 10849991
208242078 208242101 2 - 28162770 PL21 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 -0.3889272845645727 [351] [116] -3 hSpCas9 negative selection 10849992
208239925 208239948 2 - 28162770 PL21 viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 0.16036908579671938 [330] [160] 1 hSpCas9 negative selection 10849993
208251432 208251455 2 + 28162770 PL21 viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.017275557339509806 [419] [184] 0 hSpCas9 negative selection 10849994
208248409 208248432 2 + 28162770 PL21 viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 -0.2901860120937607 [235] [83] -2 hSpCas9 negative selection 10849995
208242053 208242076 2 - 28162770 PL21 viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 -2.2058527451865166 [52] [4] -8 hSpCas9 negative selection 10849996
208239909 208239932 2 + 28162770 PL21 viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 0.6151771137681638 [176] [117] 5 hSpCas9 negative selection 10849997
208239862 208239885 2 - 28162770 PL21 viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 0.5583589817683194 [737] [472] 5 hSpCas9 negative selection 10849998
208243582 208243605 2 - 28162770 PL21 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 1.4405378238800841 [363] [429] 9 hSpCas9 negative selection 10849999
208245357 208245380 2 - 28162770 P31FUJ viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.43273977492313076 [84] [73] -4 hSpCas9 negative selection 11019356
208243510 208243533 2 - 28162770 P31FUJ viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 -0.2328022044143786 [134] [134] -2 hSpCas9 negative selection 11019357
208242078 208242101 2 - 28162770 P31FUJ viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 -0.07825242885898209 [282] [314] -1 hSpCas9 negative selection 11019358
208239925 208239948 2 - 28162770 P31FUJ viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.5023457191217271 [310] [257] -4 hSpCas9 negative selection 11019359
208251432 208251455 2 + 28162770 P31FUJ viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.7939978549293366 [399] [814] 8 hSpCas9 negative selection 11019360
208248409 208248432 2 + 28162770 P31FUJ viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 0.08549950806703446 [238] [297] 0 hSpCas9 negative selection 11019361
208242053 208242076 2 - 28162770 P31FUJ viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 -0.8177647051355348 [47] [31] -6 hSpCas9 negative selection 11019362
208239909 208239932 2 + 28162770 P31FUJ viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 0.15222272579802554 [339] [443] 1 hSpCas9 negative selection 11019363
208239862 208239885 2 - 28162770 P31FUJ viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 0.04283223819904869 [778] [942] 0 hSpCas9 negative selection 11019364
208243582 208243605 2 - 28162770 P31FUJ viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.7450521547056645 [557] [1098] 8 hSpCas9 negative selection 11019365
208245357 208245380 2 - 28162770 OCIAML5 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 -0.6967883453860859 [43] [48] -4 hSpCas9 negative selection 11188722
208243510 208243533 2 - 28162770 OCIAML5 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 -0.7464563829033982 [78] [84] -5 hSpCas9 negative selection 11188723
208242078 208242101 2 - 28162770 OCIAML5 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 0.2209482264342243 [182] [384] 1 hSpCas9 negative selection 11188724
208239925 208239948 2 - 28162770 OCIAML5 viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.18755277104608112 [146] [232] -1 hSpCas9 negative selection 11188725
208251432 208251455 2 + 28162770 OCIAML5 viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 -0.2820234899785796 [323] [480] -2 hSpCas9 negative selection 11188726
208248409 208248432 2 + 28162770 OCIAML5 viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 -0.43161557539878903 [132] [177] -3 hSpCas9 negative selection 11188727
208242053 208242076 2 - 28162770 OCIAML5 viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 0.14793342913600283 [19] [39] 1 hSpCas9 negative selection 11188728
208239909 208239932 2 + 28162770 OCIAML5 viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 -0.31601367062378716 [139] [202] -2 hSpCas9 negative selection 11188729
208239862 208239885 2 - 28162770 OCIAML5 viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 0.58888562716564 [399] [1085] 5 hSpCas9 negative selection 11188730
208243582 208243605 2 - 28162770 OCIAML5 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.8788522834731411 [262] [872] 7 hSpCas9 negative selection 11188731
208245357 208245380 2 - 28162770 EOL1 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 1.4032013701453498 [121] [169] 9 hSpCas9 negative selection 11358088
208243510 208243533 2 - 28162770 EOL1 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 -0.3973803233168278 [114] [45] -3 hSpCas9 negative selection 11358089
208242078 208242101 2 - 28162770 EOL1 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 0.19566040948048014 [652] [393] 1 hSpCas9 negative selection 11358090
208239925 208239948 2 - 28162770 EOL1 viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.2473072569701773 [560] [248] -2 hSpCas9 negative selection 11358091
208251432 208251455 2 + 28162770 EOL1 viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.09171314236235739 [813] [456] 0 hSpCas9 negative selection 11358092
208248409 208248432 2 + 28162770 EOL1 viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 0.2590953529890105 [386] [243] 2 hSpCas9 negative selection 11358093
208242053 208242076 2 - 28162770 EOL1 viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 -0.475990158013194 [65] [24] -4 hSpCas9 negative selection 11358094
208239909 208239932 2 + 28162770 EOL1 viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 0.5007400626639587 [274] [204] 4 hSpCas9 negative selection 11358095
208239862 208239885 2 - 28162770 EOL1 viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 0.6974387296345035 [816] [697] 6 hSpCas9 negative selection 11358096
208243582 208243605 2 - 28162770 EOL1 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.5755994627494632 [511] [401] 5 hSpCas9 negative selection 11358097
208245357 208245380 2 - 28162770 MOLM13 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.8891858712951048 [114] [153] 6 hSpCas9 negative selection 11527454
208243510 208243533 2 - 28162770 MOLM13 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 0.16449723809464412 [115] [93] 1 hSpCas9 negative selection 11527455
208242078 208242101 2 - 28162770 MOLM13 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 0.9702339991483705 [544] [771] 7 hSpCas9 negative selection 11527456
208239925 208239948 2 - 28162770 MOLM13 viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.12924783312267965 [356] [235] -1 hSpCas9 negative selection 11527457
208251432 208251455 2 + 28162770 MOLM13 viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.910599299307977 [567] [771] 7 hSpCas9 negative selection 11527458
208248409 208248432 2 + 28162770 MOLM13 viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 0.5821855141331884 [375] [406] 4 hSpCas9 negative selection 11527459
208242053 208242076 2 - 28162770 MOLM13 viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 -0.2650065483125805 [117] [70] -2 hSpCas9 negative selection 11527460
208239909 208239932 2 + 28162770 MOLM13 viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 0.6878550654864868 [254] [296] 5 hSpCas9 negative selection 11527461
208239862 208239885 2 - 28162770 MOLM13 viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 0.9050310675302868 [841] [1139] 7 hSpCas9 negative selection 11527462
208243582 208243605 2 - 28162770 MOLM13 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.8004647206314496 [485] [611] 6 hSpCas9 negative selection 11527463
208245357 208245380 2 - 28162770 HEL viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 1.352482957431539 [106] [174] 9 hSpCas9 negative selection 11696820
208243510 208243533 2 - 28162770 HEL viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 1.4705578566176767 [79] [141] 9 hSpCas9 negative selection 11696821
208242078 208242101 2 - 28162770 HEL viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 0.5296587821896398 [450] [416] 4 hSpCas9 negative selection 11696822
208239925 208239948 2 - 28162770 HEL viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 0.6905673570909721 [355] [367] 6 hSpCas9 negative selection 11696823
208251432 208251455 2 + 28162770 HEL viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 1.3006328551753643 [449] [709] 9 hSpCas9 negative selection 11696824
208248409 208248432 2 + 28162770 HEL viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 -0.47273838541957897 [272] [125] -3 hSpCas9 negative selection 11696825
208242053 208242076 2 - 28162770 HEL viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 -0.06579835383933186 [66] [40] 0 hSpCas9 negative selection 11696826
208239909 208239932 2 + 28162770 HEL viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 0.6929245891685738 [225] [233] 6 hSpCas9 negative selection 11696827
208239862 208239885 2 - 28162770 HEL viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 0.5286670652915617 [683] [631] 4 hSpCas9 negative selection 11696828
208243582 208243605 2 - 28162770 HEL viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.3412496289704724 [402] [326] 3 hSpCas9 negative selection 11696829
208245357 208245380 2 - 28162770 MV411 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.8225522655475841 [48] [72] 7 hSpCas9 negative selection 11866186
208243510 208243533 2 - 28162770 MV411 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 0.7095433037183979 [97] [134] 6 hSpCas9 negative selection 11866187
208242078 208242101 2 - 28162770 MV411 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 0.07846137873401204 [379] [337] 0 hSpCas9 negative selection 11866188
208239925 208239948 2 - 28162770 MV411 viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.21573646954033898 [385] [279] -2 hSpCas9 negative selection 11866189
208251432 208251455 2 + 28162770 MV411 viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.7075215298385538 [401] [552] 6 hSpCas9 negative selection 11866190
208248409 208248432 2 + 28162770 MV411 viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 1.311905084660936 [185] [388] 9 hSpCas9 negative selection 11866191
208242053 208242076 2 - 28162770 MV411 viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 -0.037964668079473185 [38] [31] 0 hSpCas9 negative selection 11866192
208239909 208239932 2 + 28162770 MV411 viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 -0.0642707017867083 [210] [169] 0 hSpCas9 negative selection 11866193
208239862 208239885 2 - 28162770 MV411 viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 0.3512733617673154 [602] [647] 3 hSpCas9 negative selection 11866194
208243582 208243605 2 - 28162770 MV411 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.42199400095673356 [310] [350] 4 hSpCas9 negative selection 11866195
208245357 208245380 2 - 28162770 MONOMAC1 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 1.002271961163853 [53] [123] 8 hSpCas9 negative selection 12035552
208243510 208243533 2 - 28162770 MONOMAC1 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 -0.4507934393053368 [61] [51] -4 hSpCas9 negative selection 12035553
208242078 208242101 2 - 28162770 MONOMAC1 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 -0.03331699514394948 [232] [260] 0 hSpCas9 negative selection 12035554
208239925 208239948 2 - 28162770 MONOMAC1 viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.43582370664667014 [235] [199] -4 hSpCas9 negative selection 12035555
208251432 208251455 2 + 28162770 MONOMAC1 viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.24685551489147528 [296] [403] 2 hSpCas9 negative selection 12035556
208248409 208248432 2 + 28162770 MONOMAC1 viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 -0.015707082344991935 [111] [126] 0 hSpCas9 negative selection 12035557
208242053 208242076 2 - 28162770 MONOMAC1 viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 -0.19703684705955404 [31] [31] -2 hSpCas9 negative selection 12035558
208239909 208239932 2 + 28162770 MONOMAC1 viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 -0.03430734702144517 [133] [149] 0 hSpCas9 negative selection 12035559
208239862 208239885 2 - 28162770 MONOMAC1 viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 -0.08410331829309614 [392] [424] 0 hSpCas9 negative selection 12035560
208243582 208243605 2 - 28162770 MONOMAC1 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.7090715880305445 [245] [460] 6 hSpCas9 negative selection 12035561
208245357 208245380 2 - 28162770 OCIAML2 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 1.382821511404897 [10] [158] 9 hSpCas9 negative selection 12204918
208243510 208243533 2 - 28162770 OCIAML2 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 0.9556349294599369 [19] [214] 8 hSpCas9 negative selection 12204919
208242078 208242101 2 - 28162770 OCIAML2 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 0.3421385930018075 [75] [533] 3 hSpCas9 negative selection 12204920
208239925 208239948 2 - 28162770 OCIAML2 viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.7030759112425319 [83] [285] -5 hSpCas9 negative selection 12204921
208251432 208251455 2 + 28162770 OCIAML2 viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 0.17188369804115333 [85] [536] 1 hSpCas9 negative selection 12204922
208248409 208248432 2 + 28162770 OCIAML2 viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 -0.8394971430880791 [40] [126] -5 hSpCas9 negative selection 12204923
208242053 208242076 2 - 28162770 OCIAML2 viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 1.875145011599569 [2] [60] 9 hSpCas9 negative selection 12204924
208239909 208239932 2 + 28162770 OCIAML2 viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 0.09087370265500605 [30] [182] 0 hSpCas9 negative selection 12204925
208239862 208239885 2 - 28162770 OCIAML2 viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 0.16202941751029143 [118] [737] 1 hSpCas9 negative selection 12204926
208243582 208243605 2 - 28162770 OCIAML2 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.8610462461967632 [58] [593] 8 hSpCas9 negative selection 12204927
208245357 208245380 2 - 28162770 OCIAML3 viability ATAACCTACACACCAAGTGACGG IDH1 ENSG00000138413 0.19026366862039978 [26] [92] 1 hSpCas9 negative selection 12374284
208243510 208243533 2 - 28162770 OCIAML3 viability AAATGGCTCTGTCTAAGGGTTGG IDH1 ENSG00000138413 1.4666882913633907 [31] [266] 9 hSpCas9 negative selection 12374285
208242078 208242101 2 - 28162770 OCIAML3 viability TAGGCTCATCGACGACATGGTGG IDH1 ENSG00000138413 0.9881562270443195 [85] [514] 8 hSpCas9 negative selection 12374286
208239925 208239948 2 - 28162770 OCIAML3 viability GTAGAAGCAGAGGCTGCCCACGG IDH1 ENSG00000138413 -0.45004186594453166 [80] [178] -3 hSpCas9 negative selection 12374287
208251432 208251455 2 + 28162770 OCIAML3 viability ATGTAGATCCAATTCCACGTAGG IDH1 ENSG00000138413 1.3031239888220265 [88] [662] 9 hSpCas9 negative selection 12374288
208248409 208248432 2 + 28162770 OCIAML3 viability ACCCATCCACTCACAAGCCGGGG IDH1 ENSG00000138413 -0.7673392432097249 [52] [93] -5 hSpCas9 negative selection 12374289
208242053 208242076 2 - 28162770 OCIAML3 viability CAAGCTATGAAATCAGAGGGAGG IDH1 ENSG00000138413 0.13181739623684252 [12] [42] 1 hSpCas9 negative selection 12374290
208239909 208239932 2 + 28162770 OCIAML3 viability GTGACGGGTTACAGTCCCGTGGG IDH1 ENSG00000138413 0.3242492102343004 [58] [222] 3 hSpCas9 negative selection 12374291
208239862 208239885 2 - 28162770 OCIAML3 viability GAGACGTCCACCAATCCCATTGG IDH1 ENSG00000138413 0.8578007371101093 [137] [754] 7 hSpCas9 negative selection 12374292
208243582 208243605 2 - 28162770 OCIAML3 viability AAGGTGGTGGTGTTGCCATGGGG IDH1 ENSG00000138413 0.4530606133326157 [97] [404] 4 hSpCas9 negative selection 12374293