Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 3418
• Symbol: IDH2
• Description: isocitrate dehydrogenase (NADP(+)) 2

DataSource: http://genomecrispr.dkfz.de/#!/results/IDH2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
90102357	90102380	15	+	26472758	Jiyoye	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	0.9666027901198921	[37]	[55]	6	hSpCas9	negative selection	75769
90102283	90102306	15	-	26472758	Jiyoye	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.6551028949494588	[31]	[37]	5	hSpCas9	negative selection	75770
90088689	90088712	15	-	26472758	Jiyoye	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	-0.3935158102707199	[53]	[30]	-3	hSpCas9	negative selection	75771
90088627	90088650	15	+	26472758	Jiyoye	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	1.3002601775893614	[20]	[38]	7	hSpCas9	negative selection	75772
90088393	90088416	15	-	26472758	Jiyoye	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.34974710145680366	[204]	[196]	2	hSpCas9	negative selection	75773
90087552	90087575	15	+	26472758	Jiyoye	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	0.4071753815058732	[38]	[38]	3	hSpCas9	negative selection	75774
90087171	90087194	15	-	26472758	Jiyoye	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	-0.470834094115516	[135]	[73]	-3	hSpCas9	negative selection	75775
90085355	90085378	15	+	26472758	Jiyoye	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	-0.03419626558643296	[257]	[189]	0	hSpCas9	negative selection	75776
90085277	90085300	15	+	26472758	Jiyoye	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	0.6851601288056389	[79]	[96]	5	hSpCas9	negative selection	75777
90084871	90084894	15	-	26472758	Jiyoye	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	0.3647401151854769	[137]	[133]	2	hSpCas9	negative selection	75778
90102357	90102380	15	+	26472758	KBM7	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	-0.12658725664124648	[231,178]	[110,66]	-1	hSpCas9	negative selection	266887
90102283	90102306	15	-	26472758	KBM7	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.9395440914399543	[117,197]	[139,152]	8	hSpCas9	negative selection	266888
90088689	90088712	15	-	26472758	KBM7	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	0.13636781760818417	[218,209]	[145,79]	1	hSpCas9	negative selection	266889
90088627	90088650	15	+	26472758	KBM7	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	0.3945486078214968	[145,144]	[83,95]	4	hSpCas9	negative selection	266890
90088393	90088416	15	-	26472758	KBM7	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.8909838534060645	[1137,672]	[769,774]	8	hSpCas9	negative selection	266891
90087552	90087575	15	+	26472758	KBM7	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	-0.2453113520467496	[120,89]	[23,56]	-2	hSpCas9	negative selection	266892
90087171	90087194	15	-	26472758	KBM7	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	-0.06583525767809892	[471,423]	[245,160]	0	hSpCas9	negative selection	266893
90085355	90085378	15	+	26472758	KBM7	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	0.8882491233658847	[1333,1090]	[1114,990]	8	hSpCas9	negative selection	266894
90085277	90085300	15	+	26472758	KBM7	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	0.25087408499149055	[502,555]	[266,327]	2	hSpCas9	negative selection	266895
90084871	90084894	15	-	26472758	KBM7	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	-0.6297414202686814	[474,595]	[138,188]	-5	hSpCas9	negative selection	266896
90102357	90102380	15	+	26472758	Raji	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	0.3968901525685843	[107]	[32]	4	hSpCas9	negative selection	458005
90102283	90102306	15	-	26472758	Raji	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.9370105839848537	[65]	[7]	-6	hSpCas9	negative selection	458006
90088689	90088712	15	-	26472758	Raji	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	-0.40357838390377987	[56]	[9]	-3	hSpCas9	negative selection	458007
90088627	90088650	15	+	26472758	Raji	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	0.9781005184286331	[34]	[15]	8	hSpCas9	negative selection	458008
90088393	90088416	15	-	26472758	Raji	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	-0.015235751290356148	[404]	[92]	0	hSpCas9	negative selection	458009
90087552	90087575	15	+	26472758	Raji	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	1.1287571861661663	[66]	[33]	8	hSpCas9	negative selection	458010
90087171	90087194	15	-	26472758	Raji	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	-0.15063279569356997	[286]	[59]	-1	hSpCas9	negative selection	458011
90085355	90085378	15	+	26472758	Raji	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	0.925304333646658	[446]	[196]	8	hSpCas9	negative selection	458012
90085277	90085300	15	+	26472758	Raji	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	0.7341662117893828	[271]	[104]	7	hSpCas9	negative selection	458013
90084871	90084894	15	-	26472758	Raji	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	-0.12235086130401635	[196]	[41]	-1	hSpCas9	negative selection	458014
90102357	90102380	15	+	26472758	K562	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	0.6088301538753227	[173]	[223]	5	hSpCas9	negative selection	649123
90102283	90102306	15	-	26472758	K562	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.47069458349012305	[105]	[123]	4	hSpCas9	negative selection	649124
90088689	90088712	15	-	26472758	K562	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	-0.27015444516331133	[179]	[125]	-2	hSpCas9	negative selection	649125
90088627	90088650	15	+	26472758	K562	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	0.8837210626145093	[164]	[256]	7	hSpCas9	negative selection	649126
90088393	90088416	15	-	26472758	K562	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.13135606317981097	[596]	[551]	1	hSpCas9	negative selection	649127
90087552	90087575	15	+	26472758	K562	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	-2.077509367220915	[64]	[12]	-7	hSpCas9	negative selection	649128
90087171	90087194	15	-	26472758	K562	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	0.361625055007642	[448]	[486]	3	hSpCas9	negative selection	649129
90085355	90085378	15	+	26472758	K562	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	1.095441373094706	[687]	[1240]	8	hSpCas9	negative selection	649130
90085277	90085300	15	+	26472758	K562	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	0.5799656332846085	[484]	[611]	5	hSpCas9	negative selection	649131
90084871	90084894	15	-	26472758	K562	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	-0.5863444154503832	[465]	[261]	-4	hSpCas9	negative selection	649132
90087475	90087498	15	-	26627737	DLD1	viability	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	0.01786448101792533	[419]	[96,196,110]	0	hSpCas9	negative selection	792318
90088358	90088381	15	-	26627737	DLD1	viability	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	0.6434187573105132	[455]	[312,210,153]	6	hSpCas9	negative selection	792319
90088577	90088600	15	+	26627737	DLD1	viability	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	0.05278116685726214	[644]	[198,266,169]	0	hSpCas9	negative selection	792320
90090467	90090490	15	+	26627737	DLD1	viability	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	0.6789753729113824	[565]	[482,88,270]	6	hSpCas9	negative selection	792321
90091600	90091623	15	-	26627737	DLD1	viability	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	0.037154854673807414	[8]	[3,3,0]	0	hSpCas9	negative selection	792322
90102283	90102306	15	-	26627737	DLD1	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.5342690539192599	[789]	[232,176,110]	-5	hSpCas9	negative selection	792323
90087475	90087498	15	-	26627737	GBM cells	viability after 5 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	-0.07824614875620295	[375]	[182,198]	-1	hSpCas9	negative selection	874633
90088358	90088381	15	-	26627737	GBM cells	viability after 5 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.4483995384215903	[214]	[69,98]	-6	hSpCas9	negative selection	874634
90088577	90088600	15	+	26627737	GBM cells	viability after 5 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	-0.5311630238572991	[224]	[82,83]	-7	hSpCas9	negative selection	874635
90090467	90090490	15	+	26627737	GBM cells	viability after 5 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	0.3370349872775706	[247]	[180,154]	5	hSpCas9	negative selection	874636
90091600	90091623	15	-	26627737	GBM cells	viability after 5 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	-0.2586274021007946	[28]	[12,12]	-4	hSpCas9	negative selection	874637
90102283	90102306	15	-	26627737	GBM cells	viability after 5 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.4498142793453919	[325]	[118,136]	-6	hSpCas9	negative selection	874638
90087475	90087498	15	-	26627737	GBM cells	viability after 13 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	0.25703377818411854	[375]	[320,180]	3	hSpCas9	negative selection	956948
90088358	90088381	15	-	26627737	GBM cells	viability after 13 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.9569025480854588	[214]	[42,73]	-8	hSpCas9	negative selection	956949
90088577	90088600	15	+	26627737	GBM cells	viability after 13 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	-0.46995789032669766	[224]	[91,84]	-5	hSpCas9	negative selection	956950
90090467	90090490	15	+	26627737	GBM cells	viability after 13 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	0.4486987939191417	[247]	[165,197]	5	hSpCas9	negative selection	956951
90091600	90091623	15	-	26627737	GBM cells	viability after 13 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	-0.7837301317469789	[28]	[12,5]	-7	hSpCas9	negative selection	956952
90102283	90102306	15	-	26627737	GBM cells	viability after 13 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.13386445255432472	[325]	[158,162]	-2	hSpCas9	negative selection	956953
90087475	90087498	15	-	26627737	GBM cells	viability after 21 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	0.1863176186163008	[375]	[233,230]	2	hSpCas9	negative selection	1039263
90088358	90088381	15	-	26627737	GBM cells	viability after 21 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.9147978004350533	[214]	[62,60]	-7	hSpCas9	negative selection	1039264
90088577	90088600	15	+	26627737	GBM cells	viability after 21 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	0.018060624296340783	[224]	[128,118]	0	hSpCas9	negative selection	1039265
90090467	90090490	15	+	26627737	GBM cells	viability after 21 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	-0.13510222130895233	[247]	[129,115]	-1	hSpCas9	negative selection	1039266
90091600	90091623	15	-	26627737	GBM cells	viability after 21 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	-0.4569762529765291	[28]	[11,10]	-4	hSpCas9	negative selection	1039267
90102283	90102306	15	-	26627737	GBM cells	viability after 21 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.5758339895464755	[325]	[122,114]	-5	hSpCas9	negative selection	1039268
90087475	90087498	15	-	26627737	RPE1	viability after 9 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	0.5275046603147864	[598]	[268,271]	3	hSpCas9	negative selection	1121578
90088358	90088381	15	-	26627737	RPE1	viability after 9 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	0.8225192871020783	[880]	[592,351]	5	hSpCas9	negative selection	1121579
90088577	90088600	15	+	26627737	RPE1	viability after 9 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	0.38793634277000955	[746]	[281,336]	2	hSpCas9	negative selection	1121580
90090467	90090490	15	+	26627737	RPE1	viability after 9 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	-0.5352542253757904	[1262]	[257,291]	-4	hSpCas9	negative selection	1121581
90091600	90091623	15	-	26627737	RPE1	viability after 9 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	2.20103383205803	[33]	[51,44]	9	hSpCas9	negative selection	1121582
90102283	90102306	15	-	26627737	RPE1	viability after 9 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.8146335434788519	[1843]	[408,223]	-5	hSpCas9	negative selection	1121583
90087475	90087498	15	-	26627737	RPE1	viability after 12 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	0.618567009674036	[598]	[351,135]	4	hSpCas9	negative selection	1203893
90088358	90088381	15	-	26627737	RPE1	viability after 12 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	0.8006138651863183	[880]	[455,365]	5	hSpCas9	negative selection	1203894
90088577	90088600	15	+	26627737	RPE1	viability after 12 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	0.36508771806278545	[746]	[325,186]	2	hSpCas9	negative selection	1203895
90090467	90090490	15	+	26627737	RPE1	viability after 12 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	-0.5612166890777038	[1262]	[245,212]	-4	hSpCas9	negative selection	1203896
90091600	90091623	15	-	26627737	RPE1	viability after 12 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	0.8034868653070193	[33]	[13,17]	5	hSpCas9	negative selection	1203897
90102283	90102306	15	-	26627737	RPE1	viability after 12 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.5425145455434702	[1843]	[429,244]	-4	hSpCas9	negative selection	1203898
90087475	90087498	15	-	26627737	RPE1	viability after 15 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	0.7326408264474378	[598]	[474,94]	4	hSpCas9	negative selection	1286208
90088358	90088381	15	-	26627737	RPE1	viability after 15 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	0.779874431284555	[880]	[517,340]	5	hSpCas9	negative selection	1286209
90088577	90088600	15	+	26627737	RPE1	viability after 15 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	-0.018279141598446194	[746]	[143,270]	0	hSpCas9	negative selection	1286210
90090467	90090490	15	+	26627737	RPE1	viability after 15 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	-1.0722481118258718	[1262]	[202,137]	-6	hSpCas9	negative selection	1286211
90091600	90091623	15	-	26627737	RPE1	viability after 15 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	1.3429882544119818	[33]	[1,45]	7	hSpCas9	negative selection	1286212
90102283	90102306	15	-	26627737	RPE1	viability after 15 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-1.370360224176736	[1843]	[186,215]	-7	hSpCas9	negative selection	1286213
90087475	90087498	15	-	26627737	RPE1	viability after 18 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	0.8400259634629184	[598]	[474,90]	5	hSpCas9	negative selection	1368523
90088358	90088381	15	-	26627737	RPE1	viability after 18 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	0.6641110670747251	[880]	[514,228]	4	hSpCas9	negative selection	1368524
90088577	90088600	15	+	26627737	RPE1	viability after 18 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	-0.14930593529843517	[746]	[145,219]	-1	hSpCas9	negative selection	1368525
90090467	90090490	15	+	26627737	RPE1	viability after 18 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	-1.07713583950264	[1262]	[162,159]	-6	hSpCas9	negative selection	1368526
90091600	90091623	15	-	26627737	RPE1	viability after 18 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	1.2832300539736785	[33]	[31,11]	7	hSpCas9	negative selection	1368527
90102283	90102306	15	-	26627737	RPE1	viability after 18 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.9524790306674245	[1843]	[246,267]	-5	hSpCas9	negative selection	1368528
90087475	90087498	15	-	26627737	HeLa	viability after 8 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	0.1708740976022716	[363]	[195,196,147]	1	hSpCas9	negative selection	1450838
90088358	90088381	15	-	26627737	HeLa	viability after 8 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.4203864435201582	[833]	[312,227,280]	-4	hSpCas9	negative selection	1450839
90088577	90088600	15	+	26627737	HeLa	viability after 8 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	-0.3955201680762235	[375]	[160,166,57]	-4	hSpCas9	negative selection	1450840
90090467	90090490	15	+	26627737	HeLa	viability after 8 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	1.5603853211407892	[111]	[123,175,127]	9	hSpCas9	negative selection	1450841
90091600	90091623	15	-	26627737	HeLa	viability after 8 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	-0.10346594988700941	[42]	[33,5,15]	-1	hSpCas9	negative selection	1450842
90102283	90102306	15	-	26627737	HeLa	viability after 8 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-1.073671730132397	[758]	[328,146,40]	-8	hSpCas9	negative selection	1450843
90087475	90087498	15	-	26627737	HeLa	viability after 12 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	0.01659388595751113	[363]	[142,144,168]	0	hSpCas9	negative selection	1533153
90088358	90088381	15	-	26627737	HeLa	viability after 12 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-1.170889538934126	[833]	[119,117,223]	-8	hSpCas9	negative selection	1533154
90088577	90088600	15	+	26627737	HeLa	viability after 12 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	1.2688376198002207	[375]	[538,261,338]	8	hSpCas9	negative selection	1533155
90090467	90090490	15	+	26627737	HeLa	viability after 12 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	1.8474788345856061	[111]	[159,161,177]	9	hSpCas9	negative selection	1533156
90091600	90091623	15	-	26627737	HeLa	viability after 12 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	-0.26215195849813977	[42]	[26,12,4]	-2	hSpCas9	negative selection	1533157
90102283	90102306	15	-	26627737	HeLa	viability after 12 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.7213142988801341	[758]	[194,160,217]	-6	hSpCas9	negative selection	1533158
90087475	90087498	15	-	26627737	HeLa	viability after 15 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	-0.591150807520704	[363]	[146,78,65]	-5	hSpCas9	negative selection	1615468
90088358	90088381	15	-	26627737	HeLa	viability after 15 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-2.012565788317656	[833]	[59,20,178]	-9	hSpCas9	negative selection	1615469
90088577	90088600	15	+	26627737	HeLa	viability after 15 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	-0.06088875784337901	[375]	[41,114,295]	0	hSpCas9	negative selection	1615470
90090467	90090490	15	+	26627737	HeLa	viability after 15 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	2.1731929250162905	[111]	[210,101,311]	9	hSpCas9	negative selection	1615471
90091600	90091623	15	-	26627737	HeLa	viability after 15 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	-1.2222258766820007	[42]	[7,0,13]	-8	hSpCas9	negative selection	1615472
90102283	90102306	15	-	26627737	HeLa	viability after 15 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.29688697882605564	[758]	[256,263,231]	-3	hSpCas9	negative selection	1615473
90087475	90087498	15	-	26627737	HeLa	viability after 18 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	-0.5969188410810901	[363]	[98,63,65]	-5	hSpCas9	negative selection	1697783
90088358	90088381	15	-	26627737	HeLa	viability after 18 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-1.9774644901629224	[833]	[42,18,178]	-9	hSpCas9	negative selection	1697784
90088577	90088600	15	+	26627737	HeLa	viability after 18 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	-0.06878989211809748	[375]	[29,90,295]	0	hSpCas9	negative selection	1697785
90090467	90090490	15	+	26627737	HeLa	viability after 18 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	2.13688608993247	[111]	[135,78,311]	9	hSpCas9	negative selection	1697786
90091600	90091623	15	-	26627737	HeLa	viability after 18 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	-0.9715290841852751	[42]	[7,0,13]	-7	hSpCas9	negative selection	1697787
90102283	90102306	15	-	26627737	HeLa	viability after 18 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.2948763820084167	[758]	[171,219,231]	-3	hSpCas9	negative selection	1697788
90087475	90087498	15	-	26627737	HCT116	viability after 6 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	1.3016640912991901	[321]	[341,4]	7	hSpCas9	negative selection	1780098
90088358	90088381	15	-	26627737	HCT116	viability after 6 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.7071536847697316	[911]	[237,4]	-4	hSpCas9	negative selection	1780099
90088577	90088600	15	+	26627737	HCT116	viability after 6 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	1.918107130250557	[359]	[93,279]	8	hSpCas9	negative selection	1780100
90090467	90090490	15	+	26627737	HCT116	viability after 6 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	1.243869101722535	[489]	[233,153]	6	hSpCas9	negative selection	1780101
90091600	90091623	15	-	26627737	HCT116	viability after 6 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	-2.6468550969046967	[53]	[1,0]	-9	hSpCas9	negative selection	1780102
90102283	90102306	15	-	26627737	HCT116	viability after 6 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.8207162535305396	[539]	[89,182]	4	hSpCas9	negative selection	1780103
90087475	90087498	15	-	26627737	HCT116	viability after 8 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	1.856859519112433	[100]	[120,253,227]	9	hSpCas9	negative selection	1862413
90088358	90088381	15	-	26627737	HCT116	viability after 8 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	0.7512693102622078	[307]	[286,361,208]	7	hSpCas9	negative selection	1862414
90088577	90088600	15	+	26627737	HCT116	viability after 8 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	0.2995866235524164	[229]	[211,186,70]	3	hSpCas9	negative selection	1862415
90090467	90090490	15	+	26627737	HCT116	viability after 8 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	-0.8341728887144735	[390]	[138,113,109]	-8	hSpCas9	negative selection	1862416
90091600	90091623	15	-	26627737	HCT116	viability after 8 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	0.026333508770951752	[21]	[9,14,11]	0	hSpCas9	negative selection	1862417
90102283	90102306	15	-	26627737	HCT116	viability after 8 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.3217316013550448	[513]	[204,127,344]	-4	hSpCas9	negative selection	1862418
90087475	90087498	15	-	26627737	HCT116	viability after 9 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	-0.08367217076940969	[321]	[179,2]	0	hSpCas9	negative selection	1944728
90088358	90088381	15	-	26627737	HCT116	viability after 9 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.04795826258164704	[911]	[420,88]	0	hSpCas9	negative selection	1944729
90088577	90088600	15	+	26627737	HCT116	viability after 9 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	0.2777132822457914	[359]	[182,63]	2	hSpCas9	negative selection	1944730
90090467	90090490	15	+	26627737	HCT116	viability after 9 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	0.26974507433377526	[489]	[288,53]	2	hSpCas9	negative selection	1944731
90091600	90091623	15	-	26627737	HCT116	viability after 9 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	-3.209685329523381	[53]	[0,1]	-9	hSpCas9	negative selection	1944732
90102283	90102306	15	-	26627737	HCT116	viability after 9 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	1.1176531382219859	[539]	[685,17]	7	hSpCas9	negative selection	1944733
90087475	90087498	15	-	26627737	HCT116	viability after 12 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	1.9271794601930547	[100]	[236,139,223]	9	hSpCas9	negative selection	2027043
90088358	90088381	15	-	26627737	HCT116	viability after 12 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.28901895172310405	[307]	[231,103,51]	-3	hSpCas9	negative selection	2027044
90088577	90088600	15	+	26627737	HCT116	viability after 12 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	0.49503810032789514	[229]	[137,215,160]	5	hSpCas9	negative selection	2027045
90090467	90090490	15	+	26627737	HCT116	viability after 12 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	-0.8907608193032726	[390]	[116,113,100]	-7	hSpCas9	negative selection	2027046
90091600	90091623	15	-	26627737	HCT116	viability after 12 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	0.07213845999460977	[21]	[5,11,18]	0	hSpCas9	negative selection	2027047
90102283	90102306	15	-	26627737	HCT116	viability after 12 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-1.3547981918476393	[513]	[101,98,115]	-8	hSpCas9	negative selection	2027048
90087475	90087498	15	-	26627737	HCT116	viability after 15 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	0.9002213742051978	[100]	[133,93,99]	7	hSpCas9	negative selection	2109358
90088358	90088381	15	-	26627737	HCT116	viability after 15 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.6579985387831625	[307]	[199,117,29]	-6	hSpCas9	negative selection	2109359
90088577	90088600	15	+	26627737	HCT116	viability after 15 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	0.033982196116756846	[229]	[131,194,78]	0	hSpCas9	negative selection	2109360
90090467	90090490	15	+	26627737	HCT116	viability after 15 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	-1.0890927967240336	[390]	[84,110,117]	-8	hSpCas9	negative selection	2109361
90091600	90091623	15	-	26627737	HCT116	viability after 15 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	-0.44855466145153455	[21]	[18,3,5]	-5	hSpCas9	negative selection	2109362
90102283	90102306	15	-	26627737	HCT116	viability after 15 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-1.3656204330146042	[513]	[160,130,57]	-8	hSpCas9	negative selection	2109363
90087475	90087498	15	-	26627737	HCT116	viability after 18 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	1.3231169601631145	[100]	[140,135,86]	8	hSpCas9	negative selection	2191673
90088358	90088381	15	-	26627737	HCT116	viability after 18 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.15141822582681738	[307]	[137,176,81]	-1	hSpCas9	negative selection	2191674
90088577	90088600	15	+	26627737	HCT116	viability after 18 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	0.37130075404683166	[229]	[27,109,302]	3	hSpCas9	negative selection	2191675
90090467	90090490	15	+	26627737	HCT116	viability after 18 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	-0.851071857296009	[390]	[94,34,192]	-7	hSpCas9	negative selection	2191676
90091600	90091623	15	-	26627737	HCT116	viability after 18 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	-0.8655933612788629	[21]	[4,1,10]	-7	hSpCas9	negative selection	2191677
90102283	90102306	15	-	26627737	HCT116	viability after 18 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-1.898868762007727	[513]	[39,110,44]	-9	hSpCas9	negative selection	2191678
90100782	90100805	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAATTGCTTGGTGTTGGAGTTGG	IDH2	ENSG00000182054	0.43109395588739946	[36,91]	[7,30]	2	dCas9-VP64	positive selection	2426561
90100739	90100762	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GACTCTGCCAGCTTGTTACCTGG	IDH2	ENSG00000182054	1.7762080514991245	[220,292]	[344,30]	6	dCas9-VP64	positive selection	2426562
90100712	90100735	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGCTGGAGACAGAATACTTGG	IDH2	ENSG00000182054	-1.080759431455294	[125,912]	[21,89]	-6	dCas9-VP64	positive selection	2426563
90100782	90100805	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAATTGCTTGGTGTTGGAGTTGG	IDH2	ENSG00000182054	1.7663689631914725	[157,153]	[328,27]	8	dCas9-VP64	positive selection	2521816
90100739	90100762	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GACTCTGCCAGCTTGTTACCTGG	IDH2	ENSG00000182054	0.1802452530459655	[358,192]	[68,133]	1	dCas9-VP64	positive selection	2521817
90100712	90100735	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGCTGGAGACAGAATACTTGG	IDH2	ENSG00000182054	-0.06173357718464034	[186,189]	[66,50]	0	dCas9-VP64	positive selection	2521818
90090468	90090491	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	0.4521402093382044	[5,5]	[5,7]	8	hSpCas9	positive selection	2994714
90102283	90102306	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.4216735042816111	[2,3]	[2,0]	-6	hSpCas9	positive selection	2994715
90090524	90090547	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.39022172413304307	[2,3]	[2,0]	-5	hSpCas9	positive selection	2994716
90088358	90088381	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.2610923112282985	[3,3]	[5,0]	-4	hSpCas9	positive selection	2994717
90090468	90090491	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	0.19033916426238395	[5,5]	[5,4]	3	hSpCas9	positive selection	3062572
90102283	90102306	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.011972154076352187	[2,2]	[4,0]	0	hSpCas9	positive selection	3062573
90090524	90090547	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.03409712796081521	[2,2]	[2,0]	0	hSpCas9	positive selection	3062574
90088358	90088381	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	0.9598369021211969	[3,3]	[2,7]	9	hSpCas9	positive selection	3062575
90085048	90085071		+	24336571	A375	resistance to PLX after 7 days	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.27583706855735524	[21,13]	[14,14]	-7	hSpCas9	positive selection	3120302
90084892	90084915		-	24336571	A375	resistance to PLX after 7 days	CCATAGGTTTGCCCAGATGCTGG	IDH2	ENSG00000182054	-0.2425728635438557	[9,10]	[7,9]	-7	hSpCas9	positive selection	3120303
90084823	90084846		+	24336571	A375	resistance to PLX after 7 days	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.1413765067133258	[6,7]	[7,7]	4	hSpCas9	positive selection	3120304
90085048	90085071		+	24336571	A375	resistance to PLX after 14 days	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	0.382512132077716	[19,13]	[7,11]	4	hSpCas9	positive selection	3178095
90084892	90084915		-	24336571	A375	resistance to PLX after 14 days	CCATAGGTTTGCCCAGATGCTGG	IDH2	ENSG00000182054	-0.24958307734177276	[5,7]	[2,1]	-3	hSpCas9	positive selection	3178096
90084823	90084846		+	24336571	A375	resistance to PLX after 14 days	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.7758881821145039	[4,5]	[4,3]	6	hSpCas9	positive selection	3178097
90085048	90085071		+	24336571	A375	viability after 7 days	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	0.6703799280041395	[11]	[21,13]	8	hSpCas9	negative selection	3235888
90084892	90084915		-	24336571	A375	viability after 7 days	CCATAGGTTTGCCCAGATGCTGG	IDH2	ENSG00000182054	0.40356014550693414	[7]	[9,10]	6	hSpCas9	negative selection	3235889
90084823	90084846		+	24336571	A375	viability after 7 days	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.7546837844559277	[4]	[6,7]	9	hSpCas9	negative selection	3235890
90085048	90085071		+	24336571	A375	viability after 14 days	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	0.6305587569201635	[11]	[19,13]	7	hSpCas9	negative selection	3293681
90084892	90084915		-	24336571	A375	viability after 14 days	CCATAGGTTTGCCCAGATGCTGG	IDH2	ENSG00000182054	-0.11577784638336786	[7]	[5,7]	-1	hSpCas9	negative selection	3293682
90084823	90084846		+	24336571	A375	viability after 14 days	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.319370903677193	[4]	[4,5]	4	hSpCas9	negative selection	3293683
90090524	90090547	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	1.399345216318263	[57,57]	[0,0]	6	hSpCas9	positive selection	3373682
90085048	90085071	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.8974918976062689	[284,284]	[0,0]	-6	hSpCas9	positive selection	3373683
90084823	90084846	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	2.1280431945008687	[34,34]	[0,0]	7	hSpCas9	positive selection	3373684
90090467	90090490	15	+	26780180	HT29	viability (Avana library 4 designs)	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	0.521167658352792	[]	[]	2	hSpCas9	negative selection	3432054
90102283	90102306	15	-	26780180	HT29	viability (Avana library 4 designs)	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	1.62249883039976	[]	[]	6	hSpCas9	negative selection	3432055
90090524	90090547	15	-	26780180	HT29	viability (Avana library 4 designs)	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	2.26587328809062	[]	[]	7	hSpCas9	negative selection	3432056
90088358	90088381	15	-	26780180	HT29	viability (Avana library 4 designs)	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	1.09725992283233	[]	[]	4	hSpCas9	negative selection	3432057
90102283	90102306	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	2.55233824958942	[]	[]	4	hSpCas9	negative selection	3518015
90088358	90088381	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	3.18788532119925	[]	[]	5	hSpCas9	negative selection	3518016
90090467	90090490	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	1.40507279639326	[]	[]	2	hSpCas9	negative selection	3518017
90090524	90090547	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	4.33612675697505	[]	[]	7	hSpCas9	negative selection	3518018
90090581	90090604	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCACGGTTTGGGAGCCCGAGG	IDH2	ENSG00000182054	4.03377302452233	[]	[]	6	hSpCas9	negative selection	3518019
90088688	90088711	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	AACTATCCGGAACATCCTGGGGG	IDH2	ENSG00000182054	-0.526043018114457	[]	[]	0	hSpCas9	negative selection	3518020
90102283	90102306	15	-	26780180	A375	viability (Avana lentiGuide)	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	5.99025092362122	[]	[]	5	hSpCas9	negative selection	3626674
90088358	90088381	15	-	26780180	A375	viability (Avana lentiGuide)	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	2.43583833485581	[]	[]	2	hSpCas9	negative selection	3626675
90090467	90090490	15	+	26780180	A375	viability (Avana lentiGuide)	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	-2.03182165319534	[]	[]	-3	hSpCas9	negative selection	3626676
90090524	90090547	15	-	26780180	A375	viability (Avana lentiGuide)	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-2.20826158086297	[]	[]	-4	hSpCas9	negative selection	3626677
90090581	90090604	15	+	26780180	A375	viability (Avana lentiGuide)	GGTCACGGTTTGGGAGCCCGAGG	IDH2	ENSG00000182054	1.8659878813638	[]	[]	2	hSpCas9	negative selection	3626678
90088688	90088711	15	-	26780180	A375	viability (Avana lentiGuide)	AACTATCCGGAACATCCTGGGGG	IDH2	ENSG00000182054	-1.55356108275856	[]	[]	-3	hSpCas9	negative selection	3626679
90102283	90102306	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.2631165254541381	[3]	[5,3]	7	hSpCas9	positive selection	3735333
90088358	90088381	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	0.006588189377576218	[5]	[5,4]	0	hSpCas9	positive selection	3735334
90090467	90090490	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	-0.00575205381462035	[6]	[7,5]	0	hSpCas9	positive selection	3735335
90090524	90090547	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	0.30918710704295094	[4]	[5,5]	8	hSpCas9	positive selection	3735336
90090581	90090604	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCACGGTTTGGGAGCCCGAGG	IDH2	ENSG00000182054	0.5467483255134351	[3]	[5,5]	9	hSpCas9	positive selection	3735337
90088688	90088711	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACTATCCGGAACATCCTGGGGG	IDH2	ENSG00000182054	-0.16090602321353514	[5]	[4,4]	-3	hSpCas9	positive selection	3735338
90102283	90102306	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.3735149314441144	[5]	[2,3]	-5	hSpCas9	positive selection	3843940
90088358	90088381	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.33893644431957365	[6]	[6,1]	-4	hSpCas9	positive selection	3843941
90090467	90090490	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	0.20682161693513712	[7]	[7,6]	5	hSpCas9	positive selection	3843942
90090524	90090547	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	0.19350912521393296	[4]	[4,4]	5	hSpCas9	positive selection	3843943
90090581	90090604	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCACGGTTTGGGAGCCCGAGG	IDH2	ENSG00000182054	0.20309434384839636	[4]	[4,4]	5	hSpCas9	positive selection	3843944
90088688	90088711	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACTATCCGGAACATCCTGGGGG	IDH2	ENSG00000182054	-0.3064686611615647	[4]	[3,2]	-4	hSpCas9	positive selection	3843945
90085048	90085071	15	+	26780180	A375	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	1.69737634150392	[]	[]	9	hSpCas9	negative selection	3949922
90091571	90091594	15	-	26780180	A375	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	1.02875924838648	[]	[]	5	hSpCas9	negative selection	3949923
90090599	90090622	15	+	26780180	A375	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.137394143384881	[]	[]	0	hSpCas9	negative selection	3949924
90090524	90090547	15	-	26780180	A375	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	0.700167981802475	[]	[]	2	hSpCas9	negative selection	3949925
90084823	90084846	15	+	26780180	A375	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.754526684683809	[]	[]	3	hSpCas9	negative selection	3949926
90091631	90091654	15	-	26780180	A375	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	1.26651664372855	[]	[]	7	hSpCas9	negative selection	3949927
90085048	90085071	15	+	26780180	HT29	viability (GeCKOv2 library)	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	2.64152753980989	[]	[]	9	hSpCas9	negative selection	4057888
90091571	90091594	15	-	26780180	HT29	viability (GeCKOv2 library)	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	1.10981128296757	[]	[]	5	hSpCas9	negative selection	4057889
90090599	90090622	15	+	26780180	HT29	viability (GeCKOv2 library)	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.683376143918251	[]	[]	2	hSpCas9	negative selection	4057890
90090524	90090547	15	-	26780180	HT29	viability (GeCKOv2 library)	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	1.28368941112762	[]	[]	6	hSpCas9	negative selection	4057891
90084823	90084846	15	+	26780180	HT29	viability (GeCKOv2 library)	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	1.09236699983293	[]	[]	5	hSpCas9	negative selection	4057892
90091631	90091654	15	-	26780180	HT29	viability (GeCKOv2 library)	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	1.34446785152778	[]	[]	6	hSpCas9	negative selection	4057893
90085048	90085071	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	0.02574765275712164	[3]	[1,3]	0	hSpCas9	positive selection	4143887
90084892	90084915	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCATAGGTTTGCCCAGATGCTGG	IDH2	ENSG00000182054	0.28513377861539263	[2]	[3,1]	7	hSpCas9	positive selection	4143888
90084823	90084846	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.010507713757925863	[3]	[1,1]	0	hSpCas9	positive selection	4143889
90085048	90085071	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	1.1642446690766208	[3]	[1,0,0,6]	8	hSpCas9	positive selection	4207909
90084892	90084915	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCATAGGTTTGCCCAGATGCTGG	IDH2	ENSG00000182054	0.6420810322542525	[2]	[4,2,0,0]	4	hSpCas9	positive selection	4207910
90084823	90084846	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	-0.07993974838440063	[3]	[3,1,0,0]	-1	hSpCas9	positive selection	4207911
90091571	90091594	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.3209995785274915	[4]	[4,4]	6	hSpCas9	positive selection	4276221
90091631	90091654	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	-0.10126666942178511	[3]	[3,1]	-2	hSpCas9	positive selection	4276222
90090599	90090622	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.3345913410921393	[3]	[4,2]	6	hSpCas9	positive selection	4276223
90090524	90090547	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	0.10176820562408662	[1]	[1,0]	2	hSpCas9	positive selection	4340479
90085048	90085071	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.7159489644943796	[3]	[2,0]	-9	hSpCas9	positive selection	4340480
90084823	90084846	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	-0.2597546369051702	[1]	[1,0]	-5	hSpCas9	positive selection	4340481
90088393	90088415	15	-	27760321	OCIAML3	viability	AAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.6200722299839918	[620,473]	[527,815]	7	hSpCas9	negative selection	4408688
90088586	90088608	15	-	27760321	OCIAML3	viability	AGGCACGCCCATGGCGACCAGG	IDH2	ENSG00000182054	0.19076002819465182	[631,527]	[387,681]	2	hSpCas9	negative selection	4408689
90088687	90088709	15	-	27760321	OCIAML3	viability	CTATCCGGAACATCCTGGGGGG	IDH2	ENSG00000182054	0.6829413501955348	[669,545]	[719,810]	7	hSpCas9	negative selection	4408690
90090482	90090504	15	-	27760321	OCIAML3	viability	ACCCCTGATGAGGCCCGTGTGG	IDH2	ENSG00000182054	0.6851046223016293	[1058,931]	[1030,1533]	7	hSpCas9	negative selection	4408691
90091624	90091646	15	-	27760321	OCIAML3	viability	GATGCCGACAAAAGGATCAAGG	IDH2	ENSG00000182054	0.1684046444470838	[337,257]	[301,204]	2	hSpCas9	negative selection	4408692
90088393	90088415	15	-	27760321	OCIAML2	viability	AAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.406246918546764	[620,473]	[521,661]	5	hSpCas9	negative selection	4492151
90088586	90088608	15	-	27760321	OCIAML2	viability	AGGCACGCCCATGGCGACCAGG	IDH2	ENSG00000182054	-0.07492033828432543	[631,527]	[412,483]	-1	hSpCas9	negative selection	4492152
90088687	90088709	15	-	27760321	OCIAML2	viability	CTATCCGGAACATCCTGGGGGG	IDH2	ENSG00000182054	0.11442118411052354	[669,545]	[442,643]	1	hSpCas9	negative selection	4492153
90090482	90090504	15	-	27760321	OCIAML2	viability	ACCCCTGATGAGGCCCGTGTGG	IDH2	ENSG00000182054	0.5360908827861748	[1058,931]	[1013,1364]	7	hSpCas9	negative selection	4492154
90091624	90091646	15	-	27760321	OCIAML2	viability	GATGCCGACAAAAGGATCAAGG	IDH2	ENSG00000182054	0.33496385429961495	[337,257]	[258,357]	4	hSpCas9	negative selection	4492155
90088393	90088415	15	-	27760321	MV411	viability	AAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.8019524153456914	[620,473]	[662,567]	6	hSpCas9	negative selection	4575614
90088586	90088608	15	-	27760321	MV411	viability	AGGCACGCCCATGGCGACCAGG	IDH2	ENSG00000182054	0.4894765848758566	[631,527]	[240,976]	3	hSpCas9	negative selection	4575615
90088687	90088709	15	-	27760321	MV411	viability	CTATCCGGAACATCCTGGGGGG	IDH2	ENSG00000182054	0.8950864536002046	[669,545]	[936,449]	6	hSpCas9	negative selection	4575616
90090482	90090504	15	-	27760321	MV411	viability	ACCCCTGATGAGGCCCGTGTGG	IDH2	ENSG00000182054	1.0409957723283003	[1058,931]	[980,1901]	7	hSpCas9	negative selection	4575617
90091624	90091646	15	-	27760321	MV411	viability	GATGCCGACAAAAGGATCAAGG	IDH2	ENSG00000182054	1.2460684592839644	[337,257]	[264,759]	8	hSpCas9	negative selection	4575618
90088393	90088415	15	-	27760321	HL60	viability	AAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.33608669578988204	[620,473]	[516,605]	4	hSpCas9	negative selection	4659077
90088586	90088608	15	-	27760321	HL60	viability	AGGCACGCCCATGGCGACCAGG	IDH2	ENSG00000182054	-0.08632553803104898	[631,527]	[359,533]	-1	hSpCas9	negative selection	4659078
90088687	90088709	15	-	27760321	HL60	viability	CTATCCGGAACATCCTGGGGGG	IDH2	ENSG00000182054	0.605369394314691	[669,545]	[660,847]	7	hSpCas9	negative selection	4659079
90090482	90090504	15	-	27760321	HL60	viability	ACCCCTGATGAGGCCCGTGTGG	IDH2	ENSG00000182054	0.4729145034392963	[1058,931]	[1074,1180]	6	hSpCas9	negative selection	4659080
90091624	90091646	15	-	27760321	HL60	viability	GATGCCGACAAAAGGATCAAGG	IDH2	ENSG00000182054	-0.572364080768936	[337,257]	[143,181]	-6	hSpCas9	negative selection	4659081
90088393	90088415	15	-	27760321	HT1080	viability	AAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.05328233213415465	[473,369]	[267,71]	0	hSpCas9	negative selection	4742540
90088586	90088608	15	-	27760321	HT1080	viability	AGGCACGCCCATGGCGACCAGG	IDH2	ENSG00000182054	0.5291018729059576	[527,411]	[273,265]	2	hSpCas9	negative selection	4742541
90088687	90088709	15	-	27760321	HT1080	viability	CTATCCGGAACATCCTGGGGGG	IDH2	ENSG00000182054	0.29351387994355616	[545,425]	[158,322]	1	hSpCas9	negative selection	4742542
90090482	90090504	15	-	27760321	HT1080	viability	ACCCCTGATGAGGCCCGTGTGG	IDH2	ENSG00000182054	0.8524613325192212	[931,726]	[630,558]	4	hSpCas9	negative selection	4742543
90091624	90091646	15	-	27760321	HT1080	viability	GATGCCGACAAAAGGATCAAGG	IDH2	ENSG00000182054	-1.243422163457616	[257,201]	[21,56]	-5	hSpCas9	negative selection	4742544
90088393	90088415	15	-	27760321	HT29	viability after 7 days	AAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.03323608824198096	[473,369]	[632,552,491]	0	hSpCas9	negative selection	4826003
90088586	90088608	15	-	27760321	HT29	viability after 7 days	AGGCACGCCCATGGCGACCAGG	IDH2	ENSG00000182054	-0.008247144209062696	[527,411]	[530,574,682]	0	hSpCas9	negative selection	4826004
90088687	90088709	15	-	27760321	HT29	viability after 7 days	CTATCCGGAACATCCTGGGGGG	IDH2	ENSG00000182054	0.24587765385902682	[545,425]	[800,645,781]	4	hSpCas9	negative selection	4826005
90090482	90090504	15	-	27760321	HT29	viability after 7 days	ACCCCTGATGAGGCCCGTGTGG	IDH2	ENSG00000182054	0.4448517449325593	[931,726]	[1688,1224,1471]	6	hSpCas9	negative selection	4826006
90091624	90091646	15	-	27760321	HT29	viability after 7 days	GATGCCGACAAAAGGATCAAGG	IDH2	ENSG00000182054	0.7134745021978033	[257,201]	[340,615,476]	9	hSpCas9	negative selection	4826007
90088393	90088415	15	-	27760321	HT29	viability after 25 days	AAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.029410582467451235	[473,369]	[491,395,598]	0	hSpCas9	negative selection	4909466
90088586	90088608	15	-	27760321	HT29	viability after 25 days	AGGCACGCCCATGGCGACCAGG	IDH2	ENSG00000182054	0.14482483862954448	[527,411]	[531,619,636]	1	hSpCas9	negative selection	4909467
90088687	90088709	15	-	27760321	HT29	viability after 25 days	CTATCCGGAACATCCTGGGGGG	IDH2	ENSG00000182054	-0.15624416354482473	[545,425]	[500,522,466]	-2	hSpCas9	negative selection	4909468
90090482	90090504	15	-	27760321	HT29	viability after 25 days	ACCCCTGATGAGGCCCGTGTGG	IDH2	ENSG00000182054	0.8126832021310444	[931,726]	[1722,1539,1732]	8	hSpCas9	negative selection	4909469
90091624	90091646	15	-	27760321	HT29	viability after 25 days	GATGCCGACAAAAGGATCAAGG	IDH2	ENSG00000182054	0.5737254430568566	[257,201]	[333,510,324]	6	hSpCas9	negative selection	4909470
90088393	90088415	15	-	27760321	HT29	viability after 22 days	AAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.3422053613845769	[473,369]	[813,422,612]	3	hSpCas9	negative selection	4992929
90088586	90088608	15	-	27760321	HT29	viability after 22 days	AGGCACGCCCATGGCGACCAGG	IDH2	ENSG00000182054	-0.17104448318421925	[527,411]	[514,540,389]	-2	hSpCas9	negative selection	4992930
90088687	90088709	15	-	27760321	HT29	viability after 22 days	CTATCCGGAACATCCTGGGGGG	IDH2	ENSG00000182054	-0.11572646345307819	[545,425]	[487,483,584]	-1	hSpCas9	negative selection	4992931
90090482	90090504	15	-	27760321	HT29	viability after 22 days	ACCCCTGATGAGGCCCGTGTGG	IDH2	ENSG00000182054	0.7948631285687127	[931,726]	[2237,1312,1421]	8	hSpCas9	negative selection	4992932
90091624	90091646	15	-	27760321	HT29	viability after 22 days	GATGCCGACAAAAGGATCAAGG	IDH2	ENSG00000182054	0.48932520969383736	[257,201]	[150,494,480]	5	hSpCas9	negative selection	4992933
90088393	90088415	15	-	27760321	HT29	viability after 19 days	AAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.22421897645757163	[473,369]	[536,662,490]	2	hSpCas9	negative selection	5076392
90088586	90088608	15	-	27760321	HT29	viability after 19 days	AGGCACGCCCATGGCGACCAGG	IDH2	ENSG00000182054	0.010085022844575742	[527,411]	[441,733,440]	0	hSpCas9	negative selection	5076393
90088687	90088709	15	-	27760321	HT29	viability after 19 days	CTATCCGGAACATCCTGGGGGG	IDH2	ENSG00000182054	-0.19744124622725373	[545,425]	[559,477,425]	-2	hSpCas9	negative selection	5076394
90090482	90090504	15	-	27760321	HT29	viability after 19 days	ACCCCTGATGAGGCCCGTGTGG	IDH2	ENSG00000182054	0.5645501142708056	[931,726]	[1936,1194,1141]	5	hSpCas9	negative selection	5076395
90091624	90091646	15	-	27760321	HT29	viability after 19 days	GATGCCGACAAAAGGATCAAGG	IDH2	ENSG00000182054	0.35073269868442447	[257,201]	[278,375,344]	3	hSpCas9	negative selection	5076396
90088393	90088415	15	-	27760321	HT29	viability after 16 days	AAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	-0.11240013883550301	[473,369]	[457,290,566]	-1	hSpCas9	negative selection	5159855
90088586	90088608	15	-	27760321	HT29	viability after 16 days	AGGCACGCCCATGGCGACCAGG	IDH2	ENSG00000182054	-0.41126455956643676	[527,411]	[460,293,439]	-4	hSpCas9	negative selection	5159856
90088687	90088709	15	-	27760321	HT29	viability after 16 days	CTATCCGGAACATCCTGGGGGG	IDH2	ENSG00000182054	0.08909853956190017	[545,425]	[596,377,766]	0	hSpCas9	negative selection	5159857
90090482	90090504	15	-	27760321	HT29	viability after 16 days	ACCCCTGATGAGGCCCGTGTGG	IDH2	ENSG00000182054	0.6155946849413432	[931,726]	[1751,1331,1214]	7	hSpCas9	negative selection	5159858
90091624	90091646	15	-	27760321	HT29	viability after 16 days	GATGCCGACAAAAGGATCAAGG	IDH2	ENSG00000182054	0.5253175440830449	[257,201]	[271,290,540]	6	hSpCas9	negative selection	5159859
90088393	90088415	15	-	27760321	HT29	viability after 13 days	AAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.21865258370785126	[473,369]	[438,610,653]	2	hSpCas9	negative selection	5243318
90088586	90088608	15	-	27760321	HT29	viability after 13 days	AGGCACGCCCATGGCGACCAGG	IDH2	ENSG00000182054	-0.008192799745520618	[527,411]	[446,439,727]	0	hSpCas9	negative selection	5243319
90088687	90088709	15	-	27760321	HT29	viability after 13 days	CTATCCGGAACATCCTGGGGGG	IDH2	ENSG00000182054	0.2847769250824249	[545,425]	[886,589,588]	3	hSpCas9	negative selection	5243320
90090482	90090504	15	-	27760321	HT29	viability after 13 days	ACCCCTGATGAGGCCCGTGTGG	IDH2	ENSG00000182054	0.543663281953672	[931,726]	[1313,1644,1257]	7	hSpCas9	negative selection	5243321
90091624	90091646	15	-	27760321	HT29	viability after 13 days	GATGCCGACAAAAGGATCAAGG	IDH2	ENSG00000182054	-0.02327178234831706	[257,201]	[258,286,242]	0	hSpCas9	negative selection	5243322
90088393	90088415	15	-	27760321	HT29	viability after 10 days	AAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.33689065606875934	[473,369]	[630,693,671]	4	hSpCas9	negative selection	5326781
90088586	90088608	15	-	27760321	HT29	viability after 10 days	AGGCACGCCCATGGCGACCAGG	IDH2	ENSG00000182054	0.1123918538229397	[527,411]	[396,620,878]	1	hSpCas9	negative selection	5326782
90088687	90088709	15	-	27760321	HT29	viability after 10 days	CTATCCGGAACATCCTGGGGGG	IDH2	ENSG00000182054	-0.006129926927173235	[545,425]	[662,526,619]	0	hSpCas9	negative selection	5326783
90090482	90090504	15	-	27760321	HT29	viability after 10 days	ACCCCTGATGAGGCCCGTGTGG	IDH2	ENSG00000182054	0.6405736936374677	[931,726]	[2081,1439,1322]	8	hSpCas9	negative selection	5326784
90091624	90091646	15	-	27760321	HT29	viability after 10 days	GATGCCGACAAAAGGATCAAGG	IDH2	ENSG00000182054	0.6029069247663725	[257,201]	[221,619,470]	7	hSpCas9	negative selection	5326785
90088393	90088415	15	-	27760321	MOLM13	viability	AAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.06851152768574714	[620,473]	[409,245]	0	hSpCas9	negative selection	5410244
90088586	90088608	15	-	27760321	MOLM13	viability	AGGCACGCCCATGGCGACCAGG	IDH2	ENSG00000182054	0.8706386114433156	[631,527]	[334,817]	6	hSpCas9	negative selection	5410245
90088687	90088709	15	-	27760321	MOLM13	viability	CTATCCGGAACATCCTGGGGGG	IDH2	ENSG00000182054	-0.11527741256488011	[669,545]	[192,418]	-1	hSpCas9	negative selection	5410246
90090482	90090504	15	-	27760321	MOLM13	viability	ACCCCTGATGAGGCCCGTGTGG	IDH2	ENSG00000182054	0.4691523724843951	[1058,931]	[977,603]	3	hSpCas9	negative selection	5410247
90091624	90091646	15	-	27760321	MOLM13	viability	GATGCCGACAAAAGGATCAAGG	IDH2	ENSG00000182054	1.002097212669513	[337,257]	[385,289]	7	hSpCas9	negative selection	5410248
90102246	90102269	15	+	27661255	K562	viability	GCCTGCCTGGACCCTCCGCGCGG	IDH2	ENSG00000182054	0.1269065632982628	[576,641]	[643,433]	4	dCas9-KRAB	negative selection	5486053
90101950	90101973	15	-	27661255	K562	viability	GAGAGTGTCCCGGACCCGAAGGG	IDH2	ENSG00000182054	0.005315701490262947	[2112,2282]	[1789,1733]	0	dCas9-KRAB	negative selection	5486054
90102060	90102083	15	-	27661255	K562	viability	GGTGGGGACTTGAGGGACGGTGG	IDH2	ENSG00000182054	-0.001995444028564941	[878,1044]	[879,666]	0	dCas9-KRAB	negative selection	5486055
90102383	90102406	15	-	27661255	K562	viability	GCTCTCCAGCTTGGGATGGCCGG	IDH2	ENSG00000182054	0.6907480627604716	[16,59]	[66,32]	9	dCas9-KRAB	negative selection	5486056
90091571	90091594	15	-	27260156	BXPC3	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.013228208098009953	[1355]	[1325,1324,1471,1633]	0	hSpCas9	negative selection	5548681
90091631	90091654	15	-	27260156	BXPC3	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.13784084714229822	[474]	[476,567,548,600]	3	hSpCas9	negative selection	5548682
90090599	90090622	15	+	27260156	BXPC3	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	-0.08319744311884295	[585]	[474,565,602,691]	-2	hSpCas9	negative selection	5548683
90090524	90090547	15	-	27260156	BXPC3	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.32944018082166737	[100]	[91,29,89,131]	-6	hSpCas9	negative selection	5612939
90085048	90085071	15	+	27260156	BXPC3	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.11853683867270981	[765]	[664,654,817,833]	-3	hSpCas9	negative selection	5612940
90084823	90084846	15	+	27260156	BXPC3	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.43045870161613187	[99]	[129,158,153,116]	8	hSpCas9	negative selection	5612941
90091571	90091594	15	-	27260156	A673	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.02554438636532952	[1355]	[1723,1451,1507,1737]	0	hSpCas9	negative selection	5669932
90091631	90091654	15	-	27260156	A673	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.09979081797968455	[474]	[668,515,572,699]	2	hSpCas9	negative selection	5669933
90090599	90090622	15	+	27260156	A673	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.06853333708542725	[585]	[786,657,677,840]	1	hSpCas9	negative selection	5669934
90090524	90090547	15	-	27260156	A673	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.17424135812112063	[100]	[63,78,156,125]	-4	hSpCas9	negative selection	5734190
90085048	90085071	15	+	27260156	A673	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	0.011245213643561014	[765]	[954,826,901,1033]	0	hSpCas9	negative selection	5734191
90084823	90084846	15	+	27260156	A673	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.10907716768964582	[99]	[157,101,142,117]	2	hSpCas9	negative selection	5734192
90091571	90091594	15	-	27260156	A375	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.24393449429836855	[1355]	[1948,2072,2152,1404]	3	hSpCas9	negative selection	5791183
90091631	90091654	15	-	27260156	A375	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.12133944447648629	[474]	[750,583,499,577]	1	hSpCas9	negative selection	5791184
90090599	90090622	15	+	27260156	A375	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.0836147439233037	[585]	[808,894,580,646]	1	hSpCas9	negative selection	5791185
90090524	90090547	15	-	27260156	A375	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.18299699951515747	[100]	[201,84,83,48]	-3	hSpCas9	negative selection	5855441
90085048	90085071	15	+	27260156	A375	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	0.17025659087794998	[765]	[1058,1073,774,1111]	2	hSpCas9	negative selection	5855442
90084823	90084846	15	+	27260156	A375	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.21976882828219457	[99]	[140,164,99,140]	3	hSpCas9	negative selection	5855443
90091571	90091594	15	-	27260156	COLO741	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.055596468497707496	[1355]	[1809,1555,1644]	-1	hSpCas9	negative selection	5912434
90091631	90091654	15	-	27260156	COLO741	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.12060403189907024	[474]	[656,705,617]	2	hSpCas9	negative selection	5912435
90090599	90090622	15	+	27260156	COLO741	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.3284448302890291	[585]	[910,867,1029]	6	hSpCas9	negative selection	5912436
90090524	90090547	15	-	27260156	COLO741	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.35923207622427844	[100]	[103,126,72]	-6	hSpCas9	negative selection	5976692
90085048	90085071	15	+	27260156	COLO741	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.23372709527921948	[765]	[888,933,687]	-5	hSpCas9	negative selection	5976693
90084823	90084846	15	+	27260156	COLO741	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.1514337467431921	[99]	[56,213,146]	3	hSpCas9	negative selection	5976694
90091571	90091594	15	-	27260156	CAL120	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.1780379101123637	[1355]	[2026,1471,2238]	2	hSpCas9	negative selection	6033685
90091631	90091654	15	-	27260156	CAL120	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.2680152374168764	[474]	[643,669,808]	4	hSpCas9	negative selection	6033686
90090599	90090622	15	+	27260156	CAL120	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	-0.059382524451887075	[585]	[1031,634,485]	-1	hSpCas9	negative selection	6033687
90090524	90090547	15	-	27260156	CAL120	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	0.42907817809062965	[100]	[233,39,241]	6	hSpCas9	negative selection	6097943
90085048	90085071	15	+	27260156	CAL120	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.2696437367205073	[765]	[575,1001,761]	-4	hSpCas9	negative selection	6097944
90084823	90084846	15	+	27260156	CAL120	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.5119422260465303	[99]	[139,173,211]	7	hSpCas9	negative selection	6097945
90091571	90091594	15	-	27260156	CADOES1	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.18912704019343596	[1355]	[1243,1220,1496,1802]	3	hSpCas9	negative selection	6154936
90091631	90091654	15	-	27260156	CADOES1	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.138986304064535	[474]	[599,443,604,288]	2	hSpCas9	negative selection	6154937
90090599	90090622	15	+	27260156	CADOES1	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.2456122240845377	[585]	[706,538,851,479]	4	hSpCas9	negative selection	6154938
90090524	90090547	15	-	27260156	CADOES1	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.07038522271005654	[100]	[113,103,45,93]	-1	hSpCas9	negative selection	6219194
90085048	90085071	15	+	27260156	CADOES1	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.0415817557301662	[765]	[624,866,668,604]	0	hSpCas9	negative selection	6219195
90084823	90084846	15	+	27260156	CADOES1	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.6902128844938482	[99]	[155,204,98,139]	9	hSpCas9	negative selection	6219196
90091571	90091594	15	-	27260156	EWS502	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.06044927271951428	[1355]	[1316,1503,1647,1542]	1	hSpCas9	negative selection	6276187
90091631	90091654	15	-	27260156	EWS502	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.04983785551561457	[474]	[429,577,551,530]	0	hSpCas9	negative selection	6276188
90090599	90090622	15	+	27260156	EWS502	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.09864776794447805	[585]	[645,491,879,648]	1	hSpCas9	negative selection	6276189
90090524	90090547	15	-	27260156	EWS502	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.7505921640924429	[100]	[55,43,111,42]	-8	hSpCas9	negative selection	6340445
90085048	90085071	15	+	27260156	EWS502	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.13199415965601258	[765]	[533,976,687,776]	-2	hSpCas9	negative selection	6340446
90084823	90084846	15	+	27260156	EWS502	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.26974781109749557	[99]	[73,146,176,117]	5	hSpCas9	negative selection	6340447
90091571	90091594	15	-	27260156	EW8	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.11438634186004926	[1355]	[1080,1392,1166,1106]	2	hSpCas9	negative selection	6397438
90091631	90091654	15	-	27260156	EW8	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.009663830293903471	[474]	[565,312,300,402]	0	hSpCas9	negative selection	6397439
90090599	90090622	15	+	27260156	EW8	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.11571206245192206	[585]	[594,567,425,491]	2	hSpCas9	negative selection	6397440
90090524	90090547	15	-	27260156	EW8	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.15691037753333825	[100]	[98,41,91,59]	-3	hSpCas9	negative selection	6461696
90085048	90085071	15	+	27260156	EW8	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.12507378426293425	[765]	[680,538,530,542]	-2	hSpCas9	negative selection	6461697
90084823	90084846	15	+	27260156	EW8	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.6271839894873383	[99]	[126,95,144,128]	9	hSpCas9	negative selection	6461698
90091571	90091594	15	-	27260156	CORL105	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.15246386513779853	[1355]	[1324,1384,1720,1324]	-3	hSpCas9	negative selection	6518689
90091631	90091654	15	-	27260156	CORL105	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	-0.025123075899082824	[474]	[357,624,644,564]	0	hSpCas9	negative selection	6518690
90090599	90090622	15	+	27260156	CORL105	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.08616074156601355	[585]	[832,717,653,699]	1	hSpCas9	negative selection	6518691
90090524	90090547	15	-	27260156	CORL105	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	0.3517412532404436	[100]	[176,87,122,212]	6	hSpCas9	negative selection	6582947
90085048	90085071	15	+	27260156	CORL105	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.29809660422139445	[765]	[678,648,1057,582]	-5	hSpCas9	negative selection	6582948
90084823	90084846	15	+	27260156	CORL105	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.2422982649961536	[99]	[119,124,204,113]	4	hSpCas9	negative selection	6582949
90091571	90091594	15	-	27260156	HS294T	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.734953057726006	[1355]	[310,287,372,282]	-8	hSpCas9	negative selection	6639940
90091631	90091654	15	-	27260156	HS294T	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.4351621946605977	[474]	[187,231,284,302]	6	hSpCas9	negative selection	6639941
90090599	90090622	15	+	27260156	HS294T	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.2927345700454926	[585]	[247,336,252,270]	4	hSpCas9	negative selection	6639942
90090524	90090547	15	-	27260156	HS294T	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.8144331791199622	[100]	[14,14,30,29]	-8	hSpCas9	negative selection	6704198
90085048	90085071	15	+	27260156	HS294T	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.017071740098165256	[765]	[209,308,266,410]	0	hSpCas9	negative selection	6704199
90084823	90084846	15	+	27260156	HS294T	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	-0.012217741370425639	[99]	[18,68,22,43]	0	hSpCas9	negative selection	6704200
90091571	90091594	15	-	27260156	HCC44	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.2416143556849999	[1355]	[2299,1396,2398,1361]	4	hSpCas9	negative selection	6761191
90091631	90091654	15	-	27260156	HCC44	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	-0.06423002314702124	[474]	[594,384,610,502]	-1	hSpCas9	negative selection	6761192
90090599	90090622	15	+	27260156	HCC44	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	-0.0008463428793806793	[585]	[691,467,1041,541]	0	hSpCas9	negative selection	6761193
90090524	90090547	15	-	27260156	HCC44	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	0.3683157823141818	[100]	[193,146,170,86]	6	hSpCas9	negative selection	6825449
90085048	90085071	15	+	27260156	HCC44	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.16065614042714849	[765]	[718,610,977,836]	-3	hSpCas9	negative selection	6825450
90084823	90084846	15	+	27260156	HCC44	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	-0.19377012822933803	[99]	[63,101,137,93]	-3	hSpCas9	negative selection	6825451
90091571	90091594	15	-	27260156	G402	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.4059785811528782	[1355]	[2718,2548,1258,2323]	5	hSpCas9	negative selection	6882442
90091631	90091654	15	-	27260156	G402	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.5738941650327256	[474]	[765,875,1428,386]	7	hSpCas9	negative selection	6882443
90090599	90090622	15	+	27260156	G402	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.22892240654708101	[585]	[1025,1046,1069,272]	3	hSpCas9	negative selection	6882444
90090524	90090547	15	-	27260156	G402	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.7136744765048642	[100]	[138,0,127,38]	-7	hSpCas9	negative selection	6946700
90085048	90085071	15	+	27260156	G402	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	0.045492353075673564	[765]	[897,627,920,1358]	0	hSpCas9	negative selection	6946701
90084823	90084846	15	+	27260156	G402	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.7553320318871324	[99]	[205,147,307,159]	8	hSpCas9	negative selection	6946702
90091571	90091594	15	-	27260156	L33	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.9014623661822979	[1355]	[705,305,474,695]	-9	hSpCas9	negative selection	7003693
90091631	90091654	15	-	27260156	L33	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.12683729829377371	[474]	[565,187,256,637]	3	hSpCas9	negative selection	7003694
90090599	90090622	15	+	27260156	L33	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.3268566166368268	[585]	[650,366,461,660]	7	hSpCas9	negative selection	7003695
90090524	90090547	15	-	27260156	L33	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.00950216448489849	[100]	[118,58,29,89]	0	hSpCas9	negative selection	7067951
90085048	90085071	15	+	27260156	L33	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.3221870259095367	[765]	[691,198,407,621]	-6	hSpCas9	negative selection	7067952
90084823	90084846	15	+	27260156	L33	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	-0.4327347105237118	[99]	[79,15,62,76]	-8	hSpCas9	negative selection	7067953
90091571	90091594	15	-	27260156	K562	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.5036908805895144	[1355]	[1900,2265,1152,1559]	6	hSpCas9	negative selection	7124944
90091631	90091654	15	-	27260156	K562	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.07359445171486251	[474]	[282,320,149,939]	0	hSpCas9	negative selection	7124945
90090599	90090622	15	+	27260156	K562	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.24726960708194617	[585]	[500,712,508,725]	3	hSpCas9	negative selection	7124946
90090524	90090547	15	-	27260156	K562	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-2.426546503264506	[100]	[36,3,22,4]	-9	hSpCas9	negative selection	7189202
90085048	90085071	15	+	27260156	K562	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	0.04498130759594454	[765]	[523,520,746,955]	0	hSpCas9	negative selection	7189203
90084823	90084846	15	+	27260156	K562	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.424077339404227	[99]	[99,36,195,134]	5	hSpCas9	negative selection	7189204
90091571	90091594	15	-	27260156	HT29	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.03287352022719636	[1355]	[1637,1759,1716,1363]	0	hSpCas9	negative selection	7246195
90091631	90091654	15	-	27260156	HT29	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	-0.24020289910830805	[474]	[559,580,458,378]	-5	hSpCas9	negative selection	7246196
90090599	90090622	15	+	27260156	HT29	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.1329482235161551	[585]	[985,667,879,611]	2	hSpCas9	negative selection	7246197
90090524	90090547	15	-	27260156	HT29	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.30090981267611294	[100]	[143,101,86,71]	-5	hSpCas9	negative selection	7310453
90085048	90085071	15	+	27260156	HT29	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.15785320334108743	[765]	[887,990,994,515]	-3	hSpCas9	negative selection	7310454
90084823	90084846	15	+	27260156	HT29	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.013165722244365963	[99]	[158,96,161,77]	0	hSpCas9	negative selection	7310455
90091571	90091594	15	-	27260156	MHHES1	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.2519980829543129	[1355]	[1477,1742,1147,892]	-5	hSpCas9	negative selection	7367446
90091631	90091654	15	-	27260156	MHHES1	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	-0.01657700418925762	[474]	[267,775,712,376]	0	hSpCas9	negative selection	7367447
90090599	90090622	15	+	27260156	MHHES1	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.2691749268866938	[585]	[1024,769,880,566]	5	hSpCas9	negative selection	7367448
90090524	90090547	15	-	27260156	MHHES1	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.8489349907395547	[100]	[27,97,43,76]	-9	hSpCas9	negative selection	7431704
90085048	90085071	15	+	27260156	MHHES1	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.2851945323107457	[765]	[606,979,637,624]	-5	hSpCas9	negative selection	7431705
90084823	90084846	15	+	27260156	MHHES1	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.2388066972104601	[99]	[112,123,87,186]	4	hSpCas9	negative selection	7431706
90091571	90091594	15	-	27260156	MEWO	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.087427868255604	[1355]	[1397,1356,1297]	2	hSpCas9	negative selection	7488697
90091631	90091654	15	-	27260156	MEWO	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	-0.48322127586211644	[474]	[323,283,346]	-8	hSpCas9	negative selection	7488698
90090599	90090622	15	+	27260156	MEWO	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.14484824826368953	[585]	[840,562,459]	3	hSpCas9	negative selection	7488699
90090524	90090547	15	-	27260156	MEWO	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	0.3493710941965664	[100]	[88,128,136]	7	hSpCas9	negative selection	7552955
90085048	90085071	15	+	27260156	MEWO	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.06058552460878164	[765]	[692,580,788]	-1	hSpCas9	negative selection	7552956
90084823	90084846	15	+	27260156	MEWO	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	-0.8037710741753252	[99]	[79,29,55]	-9	hSpCas9	negative selection	7552957
90091571	90091594	15	-	27260156	LNCAPCLONEFGC	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.1764506714037959	[1355]	[1375,1302,1532,1366]	2	hSpCas9	negative selection	7609948
90091631	90091654	15	-	27260156	LNCAPCLONEFGC	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	-0.25434092579025225	[474]	[316,308,333,482]	-4	hSpCas9	negative selection	7609949
90090599	90090622	15	+	27260156	LNCAPCLONEFGC	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.3959795308272132	[585]	[527,711,833,741]	6	hSpCas9	negative selection	7609950
90090524	90090547	15	-	27260156	LNCAPCLONEFGC	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.2656953631383985	[100]	[52,62,111,82]	-4	hSpCas9	negative selection	7674206
90085048	90085071	15	+	27260156	LNCAPCLONEFGC	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	0.11610020776303687	[765]	[803,829,748,617]	1	hSpCas9	negative selection	7674207
90084823	90084846	15	+	27260156	LNCAPCLONEFGC	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	-0.11644610202881767	[99]	[88,45,72,126]	-2	hSpCas9	negative selection	7674208
90091571	90091594	15	-	27260156	PANC0327	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.24657992099417392	[1355]	[1776,970,1703,1351]	3	hSpCas9	negative selection	7731199
90091631	90091654	15	-	27260156	PANC0327	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	-0.05985194727494434	[474]	[340,307,307,668]	-1	hSpCas9	negative selection	7731200
90090599	90090622	15	+	27260156	PANC0327	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.11295169241723779	[585]	[489,322,831,631]	1	hSpCas9	negative selection	7731201
90090524	90090547	15	-	27260156	PANC0327	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.28057333712207067	[100]	[57,74,85,74]	-4	hSpCas9	negative selection	7795457
90085048	90085071	15	+	27260156	PANC0327	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.22844457978591176	[765]	[759,424,661,510]	-3	hSpCas9	negative selection	7795458
90084823	90084846	15	+	27260156	PANC0327	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.8868064061421996	[99]	[130,98,333,98]	9	hSpCas9	negative selection	7795459
90091571	90091594	15	-	27260156	NCIH2009	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.7013080861846882	[1355]	[1659,1073,858]	-7	hSpCas9	negative selection	7852450
90091631	90091654	15	-	27260156	NCIH2009	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.2569663181781954	[474]	[782,835,755]	3	hSpCas9	negative selection	7852451
90090599	90090622	15	+	27260156	NCIH2009	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.15212342583515764	[585]	[992,757,995]	2	hSpCas9	negative selection	7852452
90090524	90090547	15	-	27260156	NCIH2009	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	0.22697754875051745	[100]	[293,90,136]	3	hSpCas9	negative selection	7916708
90085048	90085071	15	+	27260156	NCIH2009	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	0.20562142888123502	[765]	[1415,976,1347]	3	hSpCas9	negative selection	7916709
90084823	90084846	15	+	27260156	NCIH2009	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.023893820634900642	[99]	[175,175,79]	0	hSpCas9	negative selection	7916710
90091571	90091594	15	-	27260156	NCIH1373	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.1061902163754902	[1355]	[1133,1022,1979,392]	-1	hSpCas9	negative selection	7973701
90091631	90091654	15	-	27260156	NCIH1373	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.21711592863978407	[474]	[610,875,407,143]	2	hSpCas9	negative selection	7973702
90090599	90090622	15	+	27260156	NCIH1373	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.4680783181576122	[585]	[1004,632,719,353]	4	hSpCas9	negative selection	7973703
90090524	90090547	15	-	27260156	NCIH1373	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	0.5765562726179032	[100]	[461,90,28,38]	5	hSpCas9	negative selection	8037959
90085048	90085071	15	+	27260156	NCIH1373	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.19574376383527547	[765]	[1028,551,522,255]	-2	hSpCas9	negative selection	8037960
90084823	90084846	15	+	27260156	NCIH1373	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.6533711295520979	[99]	[30,301,215,29]	6	hSpCas9	negative selection	8037961
90091571	90091594	15	-	27260156	PATU8902	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.5812201652548596	[1355]	[2546,2700,2396,3873]	6	hSpCas9	negative selection	8094952
90091631	90091654	15	-	27260156	PATU8902	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	-0.10166403452478644	[474]	[627,526,582,746]	-1	hSpCas9	negative selection	8094953
90090599	90090622	15	+	27260156	PATU8902	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	-0.18547314628518843	[585]	[1039,478,559,835]	-2	hSpCas9	negative selection	8094954
90090524	90090547	15	-	27260156	PATU8902	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.5569844288816448	[100]	[75,10,145,140]	-5	hSpCas9	negative selection	8159210
90085048	90085071	15	+	27260156	PATU8902	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	0.17292626369800657	[765]	[1438,810,1382,1104]	1	hSpCas9	negative selection	8159211
90084823	90084846	15	+	27260156	PATU8902	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	1.3505458700437978	[99]	[472,253,303,403]	9	hSpCas9	negative selection	8159212
90091571	90091594	15	-	27260156	PANC1	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.3995966488685676	[1355]	[1548,1804,1629,1240]	6	hSpCas9	negative selection	8216203
90091631	90091654	15	-	27260156	PANC1	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	-0.20612899689770117	[474]	[342,415,279,377]	-3	hSpCas9	negative selection	8216204
90090599	90090622	15	+	27260156	PANC1	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.21417290772682068	[585]	[541,938,527,417]	3	hSpCas9	negative selection	8216205
90090524	90090547	15	-	27260156	PANC1	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.15627326471228686	[100]	[86,30,94,85]	-3	hSpCas9	negative selection	8280461
90085048	90085071	15	+	27260156	PANC1	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.08825651826402925	[765]	[620,701,648,525]	-1	hSpCas9	negative selection	8280462
90084823	90084846	15	+	27260156	PANC1	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.24520047305204162	[99]	[106,137,134,42]	4	hSpCas9	negative selection	8280463
90091571	90091594	15	-	27260156	PANC0813	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.7123544566481871	[1355]	[1092,995,794,1010]	-7	hSpCas9	negative selection	8337454
90091631	90091654	15	-	27260156	PANC0813	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.2860015588390234	[474]	[909,538,456,825]	4	hSpCas9	negative selection	8337455
90090599	90090622	15	+	27260156	PANC0813	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.5504780746037854	[585]	[1439,865,950,823]	8	hSpCas9	negative selection	8337456
90090524	90090547	15	-	27260156	PANC0813	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	0.49898593469055275	[100]	[258,131,160,128]	7	hSpCas9	negative selection	8401712
90085048	90085071	15	+	27260156	PANC0813	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.24887270456839994	[765]	[832,834,851,527]	-4	hSpCas9	negative selection	8401713
90084823	90084846	15	+	27260156	PANC0813	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.34141042558151957	[99]	[78,118,240,149]	5	hSpCas9	negative selection	8401714
90091571	90091594	15	-	27260156	RDES	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.26446954038125914	[1355]	[1310,1894,2252,2157]	4	hSpCas9	negative selection	8458705
90091631	90091654	15	-	27260156	RDES	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.14760482633293973	[474]	[487,837,384,697]	2	hSpCas9	negative selection	8458706
90090599	90090622	15	+	27260156	RDES	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.37145949714419263	[585]	[572,863,885,1266]	6	hSpCas9	negative selection	8458707
90090524	90090547	15	-	27260156	RDES	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.406579539212665	[100]	[46,76,108,132]	-6	hSpCas9	negative selection	8522963
90085048	90085071	15	+	27260156	RDES	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.019812622195001794	[765]	[796,714,975,1016]	0	hSpCas9	negative selection	8522964
90084823	90084846	15	+	27260156	RDES	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	-0.04030415571163015	[99]	[117,52,116,168]	0	hSpCas9	negative selection	8522965
90091571	90091594	15	-	27260156	PC3	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.00962826636325742	[1355]	[803,1205,2287,1569]	0	hSpCas9	negative selection	8579956
90091631	90091654	15	-	27260156	PC3	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	-0.2693330717194984	[474]	[323,314,461,486]	-6	hSpCas9	negative selection	8579957
90090599	90090622	15	+	27260156	PC3	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	-0.014904741731768367	[585]	[354,628,942,565]	0	hSpCas9	negative selection	8579958
90090524	90090547	15	-	27260156	PC3	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	0.5885040685987808	[100]	[99,61,345,187]	9	hSpCas9	negative selection	8644214
90085048	90085071	15	+	27260156	PC3	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.38731698793604613	[765]	[306,634,869,708]	-7	hSpCas9	negative selection	8644215
90084823	90084846	15	+	27260156	PC3	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	-0.20148589604607414	[99]	[19,100,122,143]	-4	hSpCas9	negative selection	8644216
90091571	90091594	15	-	27260156	PATU8988T	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.09802775373546502	[1355]	[1379,1564,1360,1311]	1	hSpCas9	negative selection	8701207
90091631	90091654	15	-	27260156	PATU8988T	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.13178137628415146	[474]	[716,450,307,535]	2	hSpCas9	negative selection	8701208
90090599	90090622	15	+	27260156	PATU8988T	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.19792911127246188	[585]	[699,601,696,588]	3	hSpCas9	negative selection	8701209
90090524	90090547	15	-	27260156	PATU8988T	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.4867657190246488	[100]	[88,99,23,68]	-7	hSpCas9	negative selection	8765465
90085048	90085071	15	+	27260156	PATU8988T	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	0.12687715964100466	[765]	[733,806,907,779]	2	hSpCas9	negative selection	8765466
90084823	90084846	15	+	27260156	PATU8988T	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.5922582203669686	[99]	[71,90,138,286]	8	hSpCas9	negative selection	8765467
90091571	90091594	15	-	27260156	T47D	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.09734129228956134	[1355]	[1613,1590,1703,1863]	2	hSpCas9	negative selection	8822458
90091631	90091654	15	-	27260156	T47D	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.022324139465551278	[474]	[503,514,586,647]	0	hSpCas9	negative selection	8822459
90090599	90090622	15	+	27260156	T47D	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.10842571029524761	[585]	[865,734,674,666]	2	hSpCas9	negative selection	8822460
90090524	90090547	15	-	27260156	T47D	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.02555362297175323	[100]	[93,144,142,75]	0	hSpCas9	negative selection	8886716
90085048	90085071	15	+	27260156	T47D	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.014099806256049563	[765]	[896,767,849,1034]	0	hSpCas9	negative selection	8886717
90084823	90084846	15	+	27260156	T47D	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.20375209004733108	[99]	[131,135,163,102]	4	hSpCas9	negative selection	8886718
90091571	90091594	15	-	27260156	SU8686	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.39481751896812733	[1355]	[966,832,1193,1143]	-6	hSpCas9	negative selection	8943709
90091631	90091654	15	-	27260156	SU8686	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.22851975929980348	[474]	[542,482,582,614]	4	hSpCas9	negative selection	8943710
90090599	90090622	15	+	27260156	SU8686	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.3351107298167603	[585]	[647,630,811,884]	5	hSpCas9	negative selection	8943711
90090524	90090547	15	-	27260156	SU8686	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.16141206214193238	[100]	[97,78,121,53]	-3	hSpCas9	negative selection	9007967
90085048	90085071	15	+	27260156	SU8686	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.21975185923935842	[765]	[643,716,506,737]	-4	hSpCas9	negative selection	9007968
90084823	90084846	15	+	27260156	SU8686	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.22734054976653795	[99]	[117,90,111,150]	4	hSpCas9	negative selection	9007969
90091571	90091594	15	-	27260156	SKES1	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.01817660523927911	[1355]	[1690,1462,1361,1043]	0	hSpCas9	negative selection	9064960
90091631	90091654	15	-	27260156	SKES1	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.10521729406821188	[474]	[551,534,497,462]	2	hSpCas9	negative selection	9064961
90090599	90090622	15	+	27260156	SKES1	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.11418405826188888	[585]	[776,525,598,629]	2	hSpCas9	negative selection	9064962
90090524	90090547	15	-	27260156	SKES1	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.7319466147395941	[100]	[75,65,62,41]	-9	hSpCas9	negative selection	9129218
90085048	90085071	15	+	27260156	SKES1	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.25462055108544374	[765]	[678,809,574,530]	-5	hSpCas9	negative selection	9129219
90084823	90084846	15	+	27260156	SKES1	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.13258684302525792	[99]	[176,90,76,99]	3	hSpCas9	negative selection	9129220
90091571	90091594	15	-	27260156	TOV112D	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.012749058981098127	[1355]	[1670,1211,1193,1300]	0	hSpCas9	negative selection	9186211
90091631	90091654	15	-	27260156	TOV112D	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.01864036588007348	[474]	[604,536,369,439]	0	hSpCas9	negative selection	9186212
90090599	90090622	15	+	27260156	TOV112D	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.06045774282296634	[585]	[499,746,398,818]	1	hSpCas9	negative selection	9186213
90090524	90090547	15	-	27260156	TOV112D	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.02295027473026101	[100]	[107,20,206,44]	0	hSpCas9	negative selection	9250469
90085048	90085071	15	+	27260156	TOV112D	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.3344578941693746	[765]	[811,629,360,650]	-6	hSpCas9	negative selection	9250470
90084823	90084846	15	+	27260156	TOV112D	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.272128219817952	[99]	[117,93,81,180]	5	hSpCas9	negative selection	9250471
90091571	90091594	15	-	27260156	TC71	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	-0.033968489009030156	[1355]	[1587,1347,1254,1493]	-1	hSpCas9	negative selection	9307462
90091631	90091654	15	-	27260156	TC71	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	0.0011550911298417055	[474]	[585,462,424,568]	0	hSpCas9	negative selection	9307463
90090599	90090622	15	+	27260156	TC71	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	-0.035326582889501745	[585]	[761,476,576,634]	-1	hSpCas9	negative selection	9307464
90090524	90090547	15	-	27260156	TC71	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.05455048449204902	[100]	[100,120,105,87]	-1	hSpCas9	negative selection	9371720
90085048	90085071	15	+	27260156	TC71	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	-0.19380397485154732	[765]	[593,760,774,743]	-5	hSpCas9	negative selection	9371721
90084823	90084846	15	+	27260156	TC71	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.03149216676988775	[99]	[96,121,94,125]	0	hSpCas9	negative selection	9371722
90091571	90091594	15	-	27260156	TC32	viability	ATGAGATGACCCGTATTATCTGG	IDH2	ENSG00000182054	0.19901682663253073	[1355]	[1482,1029,2079,1437]	3	hSpCas9	negative selection	9428713
90091631	90091654	15	-	27260156	TC32	viability	TGCTTCTAGATGCCGACAAAAGG	IDH2	ENSG00000182054	-0.18093347604098833	[474]	[450,242,476,447]	-3	hSpCas9	negative selection	9428714
90090599	90090622	15	+	27260156	TC32	viability	CGAGGTCAAAATACTTTAGCTGG	IDH2	ENSG00000182054	0.31496027376603625	[585]	[556,722,847,591]	5	hSpCas9	negative selection	9428715
90090524	90090547	15	-	27260156	TC32	viability	GGCCACCCAGAAGTACAGTGTGG	IDH2	ENSG00000182054	-0.12603156951818173	[100]	[56,37,167,118]	-2	hSpCas9	negative selection	9492971
90085048	90085071	15	+	27260156	TC32	viability	ACGTGTCCAGGCAAAGATGCTGG	IDH2	ENSG00000182054	0.08962243979672146	[765]	[629,596,1075,855]	1	hSpCas9	negative selection	9492972
90084823	90084846	15	+	27260156	TC32	viability	GGCCGTGAATGCAGCCCGCCAGG	IDH2	ENSG00000182054	0.3246472847981958	[99]	[106,107,162,96]	6	hSpCas9	negative selection	9492973
90087475	90087498	15	-	27869803	HPAFII	viability after 27 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	-0.3554816260320284	[272]	[25,183,NaN]	-3	hSpCas9	negative selection	9555324
90088358	90088381	15	-	27869803	HPAFII	viability after 27 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.6705217597005386	[370]	[79,157,NaN]	-5	hSpCas9	negative selection	9555325
90088577	90088600	15	+	27869803	HPAFII	viability after 27 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	-1.0144867416912482	[283]	[80,67,NaN]	-6	hSpCas9	negative selection	9555326
90090467	90090490	15	+	27869803	HPAFII	viability after 27 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	0.6976306818611734	[173]	[233,76,NaN]	5	hSpCas9	negative selection	9555327
90091600	90091623	15	-	27869803	HPAFII	viability after 27 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	0.43938984275698223	[18]	[12,13,NaN]	3	hSpCas9	negative selection	9555328
90102283	90102306	15	-	27869803	HPAFII	viability after 27 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.3225346183056461	[284]	[139,102,NaN]	-2	hSpCas9	negative selection	9555329
90087475	90087498	15	-	27869803	HPAFII	viability after 15 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	0.4194991734912854	[272]	[183,521,NaN]	5	hSpCas9	negative selection	9637773
90088358	90088381	15	-	27869803	HPAFII	viability after 15 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.18341419575404283	[370]	[598,196,NaN]	-2	hSpCas9	negative selection	9637774
90088577	90088600	15	+	27869803	HPAFII	viability after 15 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	-0.2343369615348191	[283]	[219,283,NaN]	-3	hSpCas9	negative selection	9637775
90090467	90090490	15	+	27869803	HPAFII	viability after 15 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	0.6167452299058089	[173]	[488,160,NaN]	7	hSpCas9	negative selection	9637776
90091600	90091623	15	-	27869803	HPAFII	viability after 15 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	0.008010699294773715	[18]	[22,18,NaN]	0	hSpCas9	negative selection	9637777
90102283	90102306	15	-	27869803	HPAFII	viability after 15 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.20699258603637502	[284]	[355,208,NaN]	-2	hSpCas9	negative selection	9637778
90087475	90087498	15	-	27869803	ASPC1	viability after 36 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	0.38770262069652583	[845]	[375,570,242]	4	hSpCas9	negative selection	9720222
90088358	90088381	15	-	27869803	ASPC1	viability after 36 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.4572376743219034	[817]	[446,158,76]	-5	hSpCas9	negative selection	9720223
90088577	90088600	15	+	27869803	ASPC1	viability after 36 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	0.23677104766471324	[930]	[305,664,208]	2	hSpCas9	negative selection	9720224
90090467	90090490	15	+	27869803	ASPC1	viability after 36 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	-7.326528795746634e-05	[593]	[356,233,78]	0	hSpCas9	negative selection	9720225
90091600	90091623	15	-	27869803	ASPC1	viability after 36 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	0.10934799285869579	[76]	[34,16,33]	1	hSpCas9	negative selection	9720226
90102283	90102306	15	-	27869803	ASPC1	viability after 36 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.2667123063196753	[866]	[642,510,47]	2	hSpCas9	negative selection	9720227
90087475	90087498	15	-	27869803	PATU8988S	viability after 35 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	-0.310090648044333	[498]	[206,116,NaN]	-3	hSpCas9	negative selection	9802671
90088358	90088381	15	-	27869803	PATU8988S	viability after 35 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	0.12309533802200945	[667]	[292,292,NaN]	1	hSpCas9	negative selection	9802672
90088577	90088600	15	+	27869803	PATU8988S	viability after 35 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	-0.5929754153344559	[630]	[161,174,NaN]	-6	hSpCas9	negative selection	9802673
90090467	90090490	15	+	27869803	PATU8988S	viability after 35 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	0.3447947991904904	[523]	[274,260,NaN]	4	hSpCas9	negative selection	9802674
90091600	90091623	15	-	27869803	PATU8988S	viability after 35 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	0.9084478591380076	[38]	[21,36,NaN]	8	hSpCas9	negative selection	9802675
90102283	90102306	15	-	27869803	PATU8988S	viability after 35 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.459952589135015	[711]	[197,218,NaN]	-5	hSpCas9	negative selection	9802676
90087475	90087498	15	-	27869803	PATU8988S	viability after 31 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	-0.8316465836761675	[498]	[113,108,NaN]	-7	hSpCas9	negative selection	9885120
90088358	90088381	15	-	27869803	PATU8988S	viability after 31 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	0.1795743802253632	[667]	[236,383,NaN]	2	hSpCas9	negative selection	9885121
90088577	90088600	15	+	27869803	PATU8988S	viability after 31 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	-0.7001503851563406	[630]	[87,239,NaN]	-6	hSpCas9	negative selection	9885122
90090467	90090490	15	+	27869803	PATU8988S	viability after 31 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	0.6186071537028391	[523]	[161,522,NaN]	7	hSpCas9	negative selection	9885123
90091600	90091623	15	-	27869803	PATU8988S	viability after 31 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	0.3455495249454028	[38]	[17,21,NaN]	4	hSpCas9	negative selection	9885124
90102283	90102306	15	-	27869803	PATU8988S	viability after 31 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.746761688963932	[711]	[122,227,NaN]	-7	hSpCas9	negative selection	9885125
90087475	90087498	15	-	27869803	HPAFII	viability after 35 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	-0.6166628764844261	[272]	[4,185,NaN]	-4	hSpCas9	negative selection	9967569
90088358	90088381	15	-	27869803	HPAFII	viability after 35 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-1.248395885820253	[370]	[71,86,NaN]	-6	hSpCas9	negative selection	9967570
90088577	90088600	15	+	27869803	HPAFII	viability after 35 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	-0.3667330957293832	[283]	[55,173,NaN]	-2	hSpCas9	negative selection	9967571
90090467	90090490	15	+	27869803	HPAFII	viability after 35 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	1.331478833920324	[173]	[168,280,NaN]	8	hSpCas9	negative selection	9967572
90091600	90091623	15	-	27869803	HPAFII	viability after 35 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	1.2319576659545959	[18]	[31,11,NaN]	8	hSpCas9	negative selection	9967573
90102283	90102306	15	-	27869803	HPAFII	viability after 35 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.2475181776238487	[284]	[129,111,NaN]	-1	hSpCas9	negative selection	9967574
90087475	90087498	15	-	27869803	HPAFII	viability after 31 days	ACCATACTGAAAGCCTACGATGG	IDH2	ENSG00000182054	-0.09814606267373044	[272]	[0,297,NaN]	0	hSpCas9	negative selection	10050018
90088358	90088381	15	-	27869803	HPAFII	viability after 31 days	GGGCATGTACAACACCGACGAGG	IDH2	ENSG00000182054	-0.2072485640453377	[370]	[176,183,NaN]	-1	hSpCas9	negative selection	10050019
90088577	90088600	15	+	27869803	HPAFII	viability after 31 days	CCTGGCCTACCTGGTCGCCATGG	IDH2	ENSG00000182054	-0.5584383213060058	[283]	[90,126,NaN]	-4	hSpCas9	negative selection	10050020
90090467	90090490	15	+	27869803	HPAFII	viability after 31 days	ACACCCTCGCACCTTCCACACGG	IDH2	ENSG00000182054	1.3130758143426757	[173]	[200,287,NaN]	8	hSpCas9	negative selection	10050021
90091600	90091623	15	-	27869803	HPAFII	viability after 31 days	GGCGAAGCCCGTGGTGGAGATGG	IDH2	ENSG00000182054	0.7792154296283522	[18]	[24,10,NaN]	5	hSpCas9	negative selection	10050022
90102283	90102306	15	-	27869803	HPAFII	viability after 31 days	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.8347555181629506	[284]	[115,60,NaN]	-5	hSpCas9	negative selection	10050023
90102357	90102380	15	+	28162770	P31FUJ	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	0.04730571477835688	[83]	[101]	0	hSpCas9	negative selection	10172536
90102283	90102306	15	-	28162770	P31FUJ	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.35216029630677737	[73]	[110]	4	hSpCas9	negative selection	10172537
90088689	90088712	15	-	28162770	P31FUJ	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	-0.36153551853658117	[81]	[74]	-3	hSpCas9	negative selection	10172538
90088627	90088650	15	+	28162770	P31FUJ	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	1.113373436719661	[58]	[149]	9	hSpCas9	negative selection	10172539
90088393	90088416	15	-	28162770	P31FUJ	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.2977125122844013	[458]	[662]	3	hSpCas9	negative selection	10172540
90087552	90087575	15	+	28162770	P31FUJ	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	1.3409330408835234	[42]	[127]	9	hSpCas9	negative selection	10172541
90087171	90087194	15	-	28162770	P31FUJ	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	0.4574444146443613	[294]	[475]	5	hSpCas9	negative selection	10172542
90085355	90085378	15	+	28162770	P31FUJ	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	-0.043712997193940284	[456]	[520]	0	hSpCas9	negative selection	10172543
90085277	90085300	15	+	28162770	P31FUJ	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	0.6690174016467179	[265]	[496]	7	hSpCas9	negative selection	10172544
90084871	90084894	15	-	28162770	P31FUJ	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	-0.27027690983304165	[350]	[341]	-3	hSpCas9	negative selection	10172545
90102357	90102380	15	+	28162770	TF1	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10341902
90102283	90102306	15	-	28162770	TF1	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	NaN	[NaN]	[124]	1	hSpCas9	negative selection	10341903
90088689	90088712	15	-	28162770	TF1	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10341904
90088627	90088650	15	+	28162770	TF1	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10341905
90088393	90088416	15	-	28162770	TF1	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	NaN	[NaN]	[504]	1	hSpCas9	negative selection	10341906
90087552	90087575	15	+	28162770	TF1	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10341907
90087171	90087194	15	-	28162770	TF1	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	NaN	[NaN]	[248]	1	hSpCas9	negative selection	10341908
90085355	90085378	15	+	28162770	TF1	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	NaN	[NaN]	[608]	1	hSpCas9	negative selection	10341909
90085277	90085300	15	+	28162770	TF1	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	NaN	[NaN]	[244]	1	hSpCas9	negative selection	10341910
90084871	90084894	15	-	28162770	TF1	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10341911
90102357	90102380	15	+	28162770	SKM1	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	0.3773071102014012	[26]	[61]	3	hSpCas9	negative selection	10511268
90102283	90102306	15	-	28162770	SKM1	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.008073300535682115	[17]	[31]	0	hSpCas9	negative selection	10511269
90088689	90088712	15	-	28162770	SKM1	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	1.065523572719582	[19]	[73]	8	hSpCas9	negative selection	10511270
90088627	90088650	15	+	28162770	SKM1	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	1.1990599175058243	[16]	[68]	9	hSpCas9	negative selection	10511271
90088393	90088416	15	-	28162770	SKM1	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	-0.6164175643721115	[110]	[127]	-5	hSpCas9	negative selection	10511272
90087552	90087575	15	+	28162770	SKM1	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	-0.7150864941054937	[12]	[13]	-5	hSpCas9	negative selection	10511273
90087171	90087194	15	-	28162770	SKM1	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	0.3553028337859042	[64]	[146]	3	hSpCas9	negative selection	10511274
90085355	90085378	15	+	28162770	SKM1	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	0.5370793952828228	[114]	[294]	5	hSpCas9	negative selection	10511275
90085277	90085300	15	+	28162770	SKM1	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	-0.5969351423872322	[76]	[89]	-5	hSpCas9	negative selection	10511276
90084871	90084894	15	-	28162770	SKM1	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	-0.9215373715729198	[74]	[69]	-6	hSpCas9	negative selection	10511277
90102357	90102380	15	+	28162770	SKM1	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	0.3773071102014012	[26]	[61]	3	hSpCas9	negative selection	10680634
90102283	90102306	15	-	28162770	SKM1	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.008073300535682115	[17]	[31]	0	hSpCas9	negative selection	10680635
90088689	90088712	15	-	28162770	SKM1	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	1.065523572719582	[19]	[73]	8	hSpCas9	negative selection	10680636
90088627	90088650	15	+	28162770	SKM1	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	1.1990599175058243	[16]	[68]	9	hSpCas9	negative selection	10680637
90088393	90088416	15	-	28162770	SKM1	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	-0.6164175643721115	[110]	[127]	-5	hSpCas9	negative selection	10680638
90087552	90087575	15	+	28162770	SKM1	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	-0.7150864941054937	[12]	[13]	-5	hSpCas9	negative selection	10680639
90087171	90087194	15	-	28162770	SKM1	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	0.3553028337859042	[64]	[146]	3	hSpCas9	negative selection	10680640
90085355	90085378	15	+	28162770	SKM1	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	0.5370793952828228	[114]	[294]	5	hSpCas9	negative selection	10680641
90085277	90085300	15	+	28162770	SKM1	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	-0.5969351423872322	[76]	[89]	-5	hSpCas9	negative selection	10680642
90084871	90084894	15	-	28162770	SKM1	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	-0.9215373715729198	[74]	[69]	-6	hSpCas9	negative selection	10680643
90102357	90102380	15	+	28162770	PL21	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	0.9777471931528722	[90]	[77]	7	hSpCas9	negative selection	10850000
90102283	90102306	15	-	28162770	PL21	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-1.0311859316171352	[107]	[22]	-6	hSpCas9	negative selection	10850001
90088689	90088712	15	-	28162770	PL21	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	0.7467739965513771	[88]	[64]	6	hSpCas9	negative selection	10850002
90088627	90088650	15	+	28162770	PL21	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	-1.500300103651772	[51]	[7]	-7	hSpCas9	negative selection	10850003
90088393	90088416	15	-	28162770	PL21	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.12181125380436053	[491]	[232]	1	hSpCas9	negative selection	10850004
90087552	90087575	15	+	28162770	PL21	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	2.553776569104021	[35]	[91]	9	hSpCas9	negative selection	10850005
90087171	90087194	15	-	28162770	PL21	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	1.139064037737552	[192]	[184]	8	hSpCas9	negative selection	10850006
90085355	90085378	15	+	28162770	PL21	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	0.6133635433962326	[397]	[264]	5	hSpCas9	negative selection	10850007
90085277	90085300	15	+	28162770	PL21	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	-0.04251571073963367	[238]	[100]	0	hSpCas9	negative selection	10850008
90084871	90084894	15	-	28162770	PL21	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	0.12118827309449808	[168]	[79]	1	hSpCas9	negative selection	10850009
90102357	90102380	15	+	28162770	P31FUJ	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	0.04730571477835688	[83]	[101]	0	hSpCas9	negative selection	11019366
90102283	90102306	15	-	28162770	P31FUJ	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.35216029630677737	[73]	[110]	4	hSpCas9	negative selection	11019367
90088689	90088712	15	-	28162770	P31FUJ	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	-0.36153551853658117	[81]	[74]	-3	hSpCas9	negative selection	11019368
90088627	90088650	15	+	28162770	P31FUJ	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	1.113373436719661	[58]	[149]	9	hSpCas9	negative selection	11019369
90088393	90088416	15	-	28162770	P31FUJ	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.2977125122844013	[458]	[662]	3	hSpCas9	negative selection	11019370
90087552	90087575	15	+	28162770	P31FUJ	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	1.3409330408835234	[42]	[127]	9	hSpCas9	negative selection	11019371
90087171	90087194	15	-	28162770	P31FUJ	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	0.4574444146443613	[294]	[475]	5	hSpCas9	negative selection	11019372
90085355	90085378	15	+	28162770	P31FUJ	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	-0.043712997193940284	[456]	[520]	0	hSpCas9	negative selection	11019373
90085277	90085300	15	+	28162770	P31FUJ	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	0.6690174016467179	[265]	[496]	7	hSpCas9	negative selection	11019374
90084871	90084894	15	-	28162770	P31FUJ	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	-0.27027690983304165	[350]	[341]	-3	hSpCas9	negative selection	11019375
90102357	90102380	15	+	28162770	OCIAML5	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	1.2288534245195704	[25]	[109]	9	hSpCas9	negative selection	11188732
90102283	90102306	15	-	28162770	OCIAML5	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.07131214753309045	[57]	[109]	0	hSpCas9	negative selection	11188733
90088689	90088712	15	-	28162770	OCIAML5	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	-0.3666397436937552	[44]	[62]	-3	hSpCas9	negative selection	11188734
90088627	90088650	15	+	28162770	OCIAML5	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	-1.8520665708639972	[27]	[13]	-7	hSpCas9	negative selection	11188735
90088393	90088416	15	-	28162770	OCIAML5	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.5670177614775487	[177]	[475]	5	hSpCas9	negative selection	11188736
90087552	90087575	15	+	28162770	OCIAML5	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	0.5402508519147631	[7]	[20]	5	hSpCas9	negative selection	11188737
90087171	90087194	15	-	28162770	OCIAML5	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	0.3525045733852067	[127]	[294]	3	hSpCas9	negative selection	11188738
90085355	90085378	15	+	28162770	OCIAML5	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	0.8806495503008515	[203]	[677]	7	hSpCas9	negative selection	11188739
90085277	90085300	15	+	28162770	OCIAML5	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	-0.0069096160940085305	[225]	[405]	0	hSpCas9	negative selection	11188740
90084871	90084894	15	-	28162770	OCIAML5	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	0.3576520204373403	[146]	[339]	3	hSpCas9	negative selection	11188741
90102357	90102380	15	+	28162770	EOL1	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	0.4247018844873294	[180]	[127]	4	hSpCas9	negative selection	11358098
90102283	90102306	15	-	28162770	EOL1	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.6290505582412864	[90]	[30]	-4	hSpCas9	negative selection	11358099
90088689	90088712	15	-	28162770	EOL1	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	-0.8328819251553872	[141]	[41]	-5	hSpCas9	negative selection	11358100
90088627	90088650	15	+	28162770	EOL1	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	-0.3555601476222008	[118]	[48]	-3	hSpCas9	negative selection	11358101
90088393	90088416	15	-	28162770	EOL1	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.018705265394882264	[859]	[458]	0	hSpCas9	negative selection	11358102
90087552	90087575	15	+	28162770	EOL1	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	0.7801578622353598	[83]	[75]	7	hSpCas9	negative selection	11358103
90087171	90087194	15	-	28162770	EOL1	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	0.0022700669950525	[270]	[142]	0	hSpCas9	negative selection	11358104
90085355	90085378	15	+	28162770	EOL1	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	1.1460739695000595	[475]	[554]	8	hSpCas9	negative selection	11358105
90085277	90085300	15	+	28162770	EOL1	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	0.8364168612918695	[269]	[253]	7	hSpCas9	negative selection	11358106
90084871	90084894	15	-	28162770	EOL1	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	-0.3055720117905242	[311]	[132]	-2	hSpCas9	negative selection	11358107
90102357	90102380	15	+	28162770	MOLM13	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	2.173146115983447	[114]	[374]	9	hSpCas9	negative selection	11527464
90102283	90102306	15	-	28162770	MOLM13	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.1588932948712043	[104]	[67]	-1	hSpCas9	negative selection	11527465
90088689	90088712	15	-	28162770	MOLM13	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	-1.367051372184925	[131]	[36]	-6	hSpCas9	negative selection	11527466
90088627	90088650	15	+	28162770	MOLM13	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	-0.19000464163042863	[70]	[44]	-1	hSpCas9	negative selection	11527467
90088393	90088416	15	-	28162770	MOLM13	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	1.0339704165072	[563]	[834]	7	hSpCas9	negative selection	11527468
90087552	90087575	15	+	28162770	MOLM13	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	-0.2753352030933094	[76]	[45]	-2	hSpCas9	negative selection	11527469
90087171	90087194	15	-	28162770	MOLM13	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	1.0059308348782425	[249]	[362]	7	hSpCas9	negative selection	11527470
90085355	90085378	15	+	28162770	MOLM13	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	0.5833665989645148	[467]	[506]	4	hSpCas9	negative selection	11527471
90085277	90085300	15	+	28162770	MOLM13	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	0.17157882083648632	[306]	[249]	1	hSpCas9	negative selection	11527472
90084871	90084894	15	-	28162770	MOLM13	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	-0.3334266240316849	[297]	[170]	-2	hSpCas9	negative selection	11527473
90102357	90102380	15	+	28162770	HEL	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	1.223282661454508	[108]	[162]	9	hSpCas9	negative selection	11696830
90102283	90102306	15	-	28162770	HEL	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	1.3618380053730494	[64]	[106]	9	hSpCas9	negative selection	11696831
90088689	90088712	15	-	28162770	HEL	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	1.1154918291354883	[97]	[135]	8	hSpCas9	negative selection	11696832
90088627	90088650	15	+	28162770	HEL	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	0.6927795144999523	[84]	[87]	6	hSpCas9	negative selection	11696833
90088393	90088416	15	-	28162770	HEL	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.521098365867438	[605]	[556]	4	hSpCas9	negative selection	11696834
90087552	90087575	15	+	28162770	HEL	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	0.48227415980711097	[56]	[50]	4	hSpCas9	negative selection	11696835
90087171	90087194	15	-	28162770	HEL	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	-0.3381523450519385	[224]	[113]	-2	hSpCas9	negative selection	11696836
90085355	90085378	15	+	28162770	HEL	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	0.4515973446483489	[410]	[359]	4	hSpCas9	negative selection	11696837
90085277	90085300	15	+	28162770	HEL	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	0.0230109131185241	[314]	[204]	0	hSpCas9	negative selection	11696838
90084871	90084894	15	-	28162770	HEL	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	-0.394414166417109	[235]	[114]	-3	hSpCas9	negative selection	11696839
90102357	90102380	15	+	28162770	MV411	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	0.7620107236125334	[118]	[169]	7	hSpCas9	negative selection	11866196
90102283	90102306	15	-	28162770	MV411	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.5693656456701379	[43]	[54]	5	hSpCas9	negative selection	11866197
90088689	90088712	15	-	28162770	MV411	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	-0.7525624492172248	[93]	[46]	-5	hSpCas9	negative selection	11866198
90088627	90088650	15	+	28162770	MV411	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	-0.14335240224939105	[58]	[44]	-1	hSpCas9	negative selection	11866199
90088393	90088416	15	-	28162770	MV411	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.5642587552370488	[565]	[704]	5	hSpCas9	negative selection	11866200
90087552	90087575	15	+	28162770	MV411	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	-1.0913643626689833	[42]	[16]	-6	hSpCas9	negative selection	11866201
90087171	90087194	15	-	28162770	MV411	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	0.4151649965208419	[145]	[163]	3	hSpCas9	negative selection	11866202
90085355	90085378	15	+	28162770	MV411	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	0.6252844907532024	[333]	[433]	5	hSpCas9	negative selection	11866203
90085277	90085300	15	+	28162770	MV411	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	0.3798878468064249	[207]	[227]	3	hSpCas9	negative selection	11866204
90084871	90084894	15	-	28162770	MV411	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	1.1689634927596906	[169]	[321]	9	hSpCas9	negative selection	11866205
90102357	90102380	15	+	28162770	MONOMAC1	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	-1.6202482777840979	[58]	[21]	-8	hSpCas9	negative selection	12035562
90102283	90102306	15	-	28162770	MONOMAC1	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.8185252238058238	[59]	[38]	-6	hSpCas9	negative selection	12035563
90088689	90088712	15	-	28162770	MONOMAC1	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	-1.3860706714495707	[56]	[24]	-8	hSpCas9	negative selection	12035564
90088627	90088650	15	+	28162770	MONOMAC1	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	0.5707897108114128	[36]	[62]	5	hSpCas9	negative selection	12035565
90088393	90088416	15	-	28162770	MONOMAC1	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.04652018427493654	[347]	[411]	0	hSpCas9	negative selection	12035566
90087552	90087575	15	+	28162770	MONOMAC1	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	0.8029631529404462	[26]	[53]	7	hSpCas9	negative selection	12035567
90087171	90087194	15	-	28162770	MONOMAC1	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	1.1248912478278084	[125]	[314]	8	hSpCas9	negative selection	12035568
90085355	90085378	15	+	28162770	MONOMAC1	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	0.5426482484602444	[211]	[353]	5	hSpCas9	negative selection	12035569
90085277	90085300	15	+	28162770	MONOMAC1	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	1.2598208279139174	[101]	[279]	9	hSpCas9	negative selection	12035570
90084871	90084894	15	-	28162770	MONOMAC1	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	-0.46007125289334755	[131]	[109]	-4	hSpCas9	negative selection	12035571
90102357	90102380	15	+	28162770	OCIAML2	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	0.07585852766435919	[18]	[110]	0	hSpCas9	negative selection	12204928
90102283	90102306	15	-	28162770	OCIAML2	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	0.5882638638114076	[14]	[124]	6	hSpCas9	negative selection	12204929
90088689	90088712	15	-	28162770	OCIAML2	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	-0.2884264940214123	[12]	[58]	-2	hSpCas9	negative selection	12204930
90088627	90088650	15	+	28162770	OCIAML2	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	0.8147723936200871	[19]	[194]	7	hSpCas9	negative selection	12204931
90088393	90088416	15	-	28162770	OCIAML2	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.08973070224591673	[68]	[406]	0	hSpCas9	negative selection	12204932
90087552	90087575	15	+	28162770	OCIAML2	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	1.1796241357307142	[8]	[112]	9	hSpCas9	negative selection	12204933
90087171	90087194	15	-	28162770	OCIAML2	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	1.000161655559684	[22]	[254]	8	hSpCas9	negative selection	12204934
90085355	90085378	15	+	28162770	OCIAML2	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	0.5605188733285028	[62]	[514]	5	hSpCas9	negative selection	12204935
90085277	90085300	15	+	28162770	OCIAML2	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	0.6115192161117103	[31]	[270]	6	hSpCas9	negative selection	12204936
90084871	90084894	15	-	28162770	OCIAML2	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	0.17322636453256351	[23]	[149]	1	hSpCas9	negative selection	12204937
90102357	90102380	15	+	28162770	OCIAML3	viability	AGAGCGAGCGCACGACCCGCAGG	IDH2	ENSG00000182054	-0.35008205743807386	[18]	[44]	-3	hSpCas9	negative selection	12374294
90102283	90102306	15	-	28162770	OCIAML3	viability	CCACCTCGCAAGAGCAGCCGCGG	IDH2	ENSG00000182054	-0.594007640324163	[12]	[25]	-4	hSpCas9	negative selection	12374295
90088689	90088712	15	-	28162770	OCIAML3	viability	GAACTATCCGGAACATCCTGGGG	IDH2	ENSG00000182054	-0.13457602168686567	[11]	[32]	-1	hSpCas9	negative selection	12374296
90088627	90088650	15	+	28162770	OCIAML3	viability	GTCCAGCCAGGGACTAGGCGTGG	IDH2	ENSG00000182054	0.29676328992107837	[23]	[88]	3	hSpCas9	negative selection	12374297
90088393	90088416	15	-	28162770	OCIAML3	viability	GAAGTGTACAACTTCCCCGCAGG	IDH2	ENSG00000182054	0.32682214624222905	[102]	[389]	3	hSpCas9	negative selection	12374298
90087552	90087575	15	+	28162770	OCIAML3	viability	GCTGTGCGCAAAACCTGAGATGG	IDH2	ENSG00000182054	-0.14334623131459812	[14]	[40]	-1	hSpCas9	negative selection	12374299
90087171	90087194	15	-	28162770	OCIAML3	viability	CAGGTCCTCAAGTCTTCGGGTGG	IDH2	ENSG00000182054	0.458080870824291	[67]	[281]	4	hSpCas9	negative selection	12374300
90085355	90085378	15	+	28162770	OCIAML3	viability	GGACGGACGTCATCAGGCCAAGG	IDH2	ENSG00000182054	-0.34182061672736186	[88]	[211]	-3	hSpCas9	negative selection	12374301
90085277	90085300	15	+	28162770	OCIAML3	viability	TCTGGTGCTCCCGATAGTGGCGG	IDH2	ENSG00000182054	0.1250915330485292	[64]	[213]	1	hSpCas9	negative selection	12374302
90084871	90084894	15	-	28162770	OCIAML3	viability	GGAGAAGGTGTGCGTGGAGACGG	IDH2	ENSG00000182054	0.96111963085623	[56]	[334]	8	hSpCas9	negative selection	12374303