Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 3425
• Symbol: IDUA
• Description: alpha-L-iduronidase

DataSource: http://genomecrispr.dkfz.de/#!/results/IDUA

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
987869	987892	4	-	26472758	Jiyoye	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	2.064287667982865	[90]	[286]	8	hSpCas9	negative selection	75846
1002775	1002798	4	+	26472758	Jiyoye	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	1.9921378822270297	[22]	[68]	8	hSpCas9	negative selection	75847
1002897	1002920	4	+	26472758	Jiyoye	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	1.2916981640859373	[129]	[239]	7	hSpCas9	negative selection	75848
1000903	1000926	4	-	26472758	Jiyoye	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	1.1718859661549836	[102]	[174]	7	hSpCas9	negative selection	75849
1001749	1001772	4	-	26472758	Jiyoye	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	-0.3033180012991418	[179]	[109]	-2	hSpCas9	negative selection	75850
1001771	1001794	4	-	26472758	Jiyoye	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	0.9546631768083667	[25]	[37]	6	hSpCas9	negative selection	75851
1001781	1001804	4	-	26472758	Jiyoye	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	5.655102894949458	[0]	[37]	9	hSpCas9	negative selection	75852
1002103	1002126	4	+	26472758	Jiyoye	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	0.20923600389396424	[38]	[33]	1	hSpCas9	negative selection	75853
1002315	1002338	4	-	26472758	Jiyoye	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	-0.27802878497059114	[364]	[226]	-2	hSpCas9	negative selection	75854
1002372	1002395	4	-	26472758	Jiyoye	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	-0.024312638553564553	[146]	[108]	0	hSpCas9	negative selection	75855
991666	991689	4	-	26472758	Jiyoye	viability	GAGCCTCTGCAGCAGGGCAGAGG	IDUA	ENSG00000127415	-0.9147527133814888	[69]	[27]	-6	hSpCas9	negative selection	148926
991304	991327	4	-	26472758	Jiyoye	viability	CAGCCTGCTTTGCCTCATGGTGG	IDUA	ENSG00000127415	-1.9774884687294514	[46]	[8]	-8	hSpCas9	negative selection	148927
991612	991635	4	+	26472758	Jiyoye	viability	AGCATCTCACGCAGACCCCGGGG	IDUA	ENSG00000127415	0.5115120413206092	[159]	[171]	4	hSpCas9	negative selection	148928
991515	991538	4	+	26472758	Jiyoye	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.11291245311098508	[336]	[234]	-1	hSpCas9	negative selection	148929
991422	991445	4	+	26472758	Jiyoye	viability	GGCCAGCAATGAGTAGGCGATGG	IDUA	ENSG00000127415	0.9635687300302587	[118]	[174]	6	hSpCas9	negative selection	148930
991317	991340	4	+	26472758	Jiyoye	viability	AAGCAGGCTGAAGATGCCCACGG	IDUA	ENSG00000127415	0.9058380358328093	[154]	[218]	6	hSpCas9	negative selection	148931
991140	991163	4	+	26472758	Jiyoye	viability	GGTCATCAGCGTGAGGGCGGTGG	IDUA	ENSG00000127415	-0.12333933519290641	[38]	[26]	-1	hSpCas9	negative selection	148932
991489	991512	4	+	26472758	Jiyoye	viability	TCGCCTGCCAGGTACTCCCGCGG	IDUA	ENSG00000127415	-0.7788366041040757	[495]	[217]	-5	hSpCas9	negative selection	148933
991274	991297	4	-	26472758	Jiyoye	viability	GGTGGACCGGGAGCTCCAGCTGG	IDUA	ENSG00000127415	0.49737319047745165	[30]	[32]	4	hSpCas9	negative selection	148934
991368	991391	4	+	26472758	Jiyoye	viability	GTAGATGAGGTTGGCGAAGAAGG	IDUA	ENSG00000127415	-2.3152906429652176	[131]	[19]	-8	hSpCas9	negative selection	148935
987869	987892	4	-	26472758	KBM7	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.37484732782068675	[1090,952]	[624,618]	4	hSpCas9	negative selection	266964
1002775	1002798	4	+	26472758	KBM7	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	1.0434633778316345	[172,133]	[155,139]	9	hSpCas9	negative selection	266965
1002897	1002920	4	+	26472758	KBM7	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	0.6016527738890559	[1139,587]	[668,536]	6	hSpCas9	negative selection	266966
1000903	1000926	4	-	26472758	KBM7	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.8224480804799723	[441,325]	[260,364]	8	hSpCas9	negative selection	266967
1001749	1001772	4	-	26472758	KBM7	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	0.831609158450529	[669,358]	[337,491]	8	hSpCas9	negative selection	266968
1001771	1001794	4	-	26472758	KBM7	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	0.9419967583551916	[132,103]	[101,109]	8	hSpCas9	negative selection	266969
1001781	1001804	4	-	26472758	KBM7	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	0.4916254157854767	[92,39]	[53,31]	5	hSpCas9	negative selection	266970
1002103	1002126	4	+	26472758	KBM7	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	0.8406107674344875	[173,126]	[175,79]	8	hSpCas9	negative selection	266971
1002315	1002338	4	-	26472758	KBM7	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	1.010201113444998	[934,862]	[954,759]	9	hSpCas9	negative selection	266972
1002372	1002395	4	-	26472758	KBM7	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	0.6907376962539077	[544,438]	[255,473]	7	hSpCas9	negative selection	266973
991666	991689	4	-	26472758	KBM7	viability	GAGCCTCTGCAGCAGGGCAGAGG	IDUA	ENSG00000127415	0.1450529464702345	[484,294]	[175,218]	1	hSpCas9	negative selection	340044
991304	991327	4	-	26472758	KBM7	viability	CAGCCTGCTTTGCCTCATGGTGG	IDUA	ENSG00000127415	1.341893799109605	[38,117]	[186,19]	9	hSpCas9	negative selection	340045
991612	991635	4	+	26472758	KBM7	viability	AGCATCTCACGCAGACCCCGGGG	IDUA	ENSG00000127415	0.8607648029401567	[734,413]	[574,392]	8	hSpCas9	negative selection	340046
991515	991538	4	+	26472758	KBM7	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.5331699718852725	[1206,867]	[837,571]	6	hSpCas9	negative selection	340047
991422	991445	4	+	26472758	KBM7	viability	GGCCAGCAATGAGTAGGCGATGG	IDUA	ENSG00000127415	1.1119856362259122	[783,438]	[482,716]	9	hSpCas9	negative selection	340048
991317	991340	4	+	26472758	KBM7	viability	AAGCAGGCTGAAGATGCCCACGG	IDUA	ENSG00000127415	0.4857270397758715	[825,570]	[414,487]	5	hSpCas9	negative selection	340049
991140	991163	4	+	26472758	KBM7	viability	GGTCATCAGCGTGAGGGCGGTGG	IDUA	ENSG00000127415	0.6447091370035108	[296,245]	[214,183]	7	hSpCas9	negative selection	340050
991489	991512	4	+	26472758	KBM7	viability	TCGCCTGCCAGGTACTCCCGCGG	IDUA	ENSG00000127415	0.5638450202665715	[1322,971]	[770,804]	6	hSpCas9	negative selection	340051
991274	991297	4	-	26472758	KBM7	viability	GGTGGACCGGGAGCTCCAGCTGG	IDUA	ENSG00000127415	1.4199771119994908	[172,95]	[153,174]	9	hSpCas9	negative selection	340052
991368	991391	4	+	26472758	KBM7	viability	GTAGATGAGGTTGGCGAAGAAGG	IDUA	ENSG00000127415	0.7989052064351303	[243,431]	[111,440]	8	hSpCas9	negative selection	340053
987869	987892	4	-	26472758	Raji	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	-0.35204808326369796	[505]	[91]	-3	hSpCas9	negative selection	458082
1002775	1002798	4	+	26472758	Raji	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	0.2842612974576788	[137]	[38]	2	hSpCas9	negative selection	458083
1002897	1002920	4	+	26472758	Raji	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	-0.035304881794910536	[445]	[100]	0	hSpCas9	negative selection	458084
1000903	1000926	4	-	26472758	Raji	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.35340196419179204	[198]	[58]	3	hSpCas9	negative selection	458085
1001749	1001772	4	-	26472758	Raji	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	-0.15758867470168691	[297]	[61]	-1	hSpCas9	negative selection	458086
1001771	1001794	4	-	26472758	Raji	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	1.7512397251483243	[31]	[24]	9	hSpCas9	negative selection	458087
1001781	1001804	4	-	26472758	Raji	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	-0.1556508704601942	[47]	[9]	-1	hSpCas9	negative selection	458088
1002103	1002126	4	+	26472758	Raji	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	0.7928729120487201	[96]	[38]	7	hSpCas9	negative selection	458089
1002315	1002338	4	-	26472758	Raji	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	0.5388154729031123	[524]	[176]	5	hSpCas9	negative selection	458090
1002372	1002395	4	-	26472758	Raji	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	-0.23430781433519288	[293]	[57]	-2	hSpCas9	negative selection	458091
991666	991689	4	-	26472758	Raji	viability	GAGCCTCTGCAGCAGGGCAGAGG	IDUA	ENSG00000127415	0.8577696453021274	[106]	[44]	7	hSpCas9	negative selection	531162
991304	991327	4	-	26472758	Raji	viability	CAGCCTGCTTTGCCTCATGGTGG	IDUA	ENSG00000127415	1.827275616180864	[16]	[13]	9	hSpCas9	negative selection	531163
991612	991635	4	+	26472758	Raji	viability	AGCATCTCACGCAGACCCCGGGG	IDUA	ENSG00000127415	1.3444227326744487	[223]	[131]	9	hSpCas9	negative selection	531164
991515	991538	4	+	26472758	Raji	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	1.4465410698059733	[282]	[178]	9	hSpCas9	negative selection	531165
991422	991445	4	+	26472758	Raji	viability	GGCCAGCAATGAGTAGGCGATGG	IDUA	ENSG00000127415	0.5164962006953377	[243]	[80]	5	hSpCas9	negative selection	531166
991317	991340	4	+	26472758	Raji	viability	AAGCAGGCTGAAGATGCCCACGG	IDUA	ENSG00000127415	-0.4842426956285675	[433]	[71]	-4	hSpCas9	negative selection	531167
991140	991163	4	+	26472758	Raji	viability	GGTCATCAGCGTGAGGGCGGTGG	IDUA	ENSG00000127415	-0.06254146606871291	[152]	[33]	0	hSpCas9	negative selection	531168
991489	991512	4	+	26472758	Raji	viability	TCGCCTGCCAGGTACTCCCGCGG	IDUA	ENSG00000127415	-0.15200309344505003	[631]	[131]	-1	hSpCas9	negative selection	531169
991274	991297	4	-	26472758	Raji	viability	GGTGGACCGGGAGCTCCAGCTGG	IDUA	ENSG00000127415	0.4193275416883395	[57]	[17]	4	hSpCas9	negative selection	531170
991368	991391	4	+	26472758	Raji	viability	GTAGATGAGGTTGGCGAAGAAGG	IDUA	ENSG00000127415	0.26235819534994037	[193]	[53]	2	hSpCas9	negative selection	531171
987869	987892	4	-	26472758	K562	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.3463568914326658	[1119]	[1201]	2	hSpCas9	negative selection	649200
1002775	1002798	4	+	26472758	K562	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	0.7797504606630025	[137]	[199]	6	hSpCas9	negative selection	649201
1002897	1002920	4	+	26472758	K562	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	0.19086925938971266	[740]	[713]	1	hSpCas9	negative selection	649202
1000903	1000926	4	-	26472758	K562	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.40416235276052426	[315]	[352]	3	hSpCas9	negative selection	649203
1001749	1001772	4	-	26472758	K562	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	-0.19279015261101728	[305]	[225]	-1	hSpCas9	negative selection	649204
1001771	1001794	4	-	26472758	K562	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	0.7167894020112424	[110]	[153]	6	hSpCas9	negative selection	649205
1001781	1001804	4	-	26472758	K562	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	-1.9833871898563658	[88]	[18]	-7	hSpCas9	negative selection	649206
1002103	1002126	4	+	26472758	K562	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	1.0170082315633744	[119]	[204]	8	hSpCas9	negative selection	649207
1002315	1002338	4	-	26472758	K562	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	1.2488051556149968	[820]	[1646]	9	hSpCas9	negative selection	649208
1002372	1002395	4	-	26472758	K562	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	1.2090331289305503	[453]	[885]	8	hSpCas9	negative selection	649209
991666	991689	4	-	26472758	K562	viability	GAGCCTCTGCAGCAGGGCAGAGG	IDUA	ENSG00000127415	-1.4456872770790439	[312]	[96]	-6	hSpCas9	negative selection	722280
991304	991327	4	-	26472758	K562	viability	CAGCCTGCTTTGCCTCATGGTGG	IDUA	ENSG00000127415	-1.3902968082518092	[58]	[18]	-6	hSpCas9	negative selection	722281
991612	991635	4	+	26472758	K562	viability	AGCATCTCACGCAGACCCCGGGG	IDUA	ENSG00000127415	0.10151425352121612	[561]	[508]	0	hSpCas9	negative selection	722282
991515	991538	4	+	26472758	K562	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.6550330399111052	[734]	[976]	5	hSpCas9	negative selection	722283
991422	991445	4	+	26472758	K562	viability	GGCCAGCAATGAGTAGGCGATGG	IDUA	ENSG00000127415	0.9244637742412783	[547]	[877]	7	hSpCas9	negative selection	722284
991317	991340	4	+	26472758	K562	viability	AAGCAGGCTGAAGATGCCCACGG	IDUA	ENSG00000127415	0.2742607391953724	[621]	[634]	2	hSpCas9	negative selection	722285
991140	991163	4	+	26472758	K562	viability	GGTCATCAGCGTGAGGGCGGTGG	IDUA	ENSG00000127415	0.80479559010933	[216]	[319]	6	hSpCas9	negative selection	722286
991489	991512	4	+	26472758	K562	viability	TCGCCTGCCAGGTACTCCCGCGG	IDUA	ENSG00000127415	0.36278092398983985	[806]	[875]	3	hSpCas9	negative selection	722287
991274	991297	4	-	26472758	K562	viability	GGTGGACCGGGAGCTCCAGCTGG	IDUA	ENSG00000127415	1.0538968216170213	[96]	[169]	8	hSpCas9	negative selection	722288
991368	991391	4	+	26472758	K562	viability	GTAGATGAGGTTGGCGAAGAAGG	IDUA	ENSG00000127415	1.3726222869921128	[381]	[834]	9	hSpCas9	negative selection	722289
987209	987232	4	-	26627737	DLD1	viability	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	-0.4010104024919481	[84]	[30,26,4]	-4	hSpCas9	negative selection	826298
987827	987850	4	-	26627737	DLD1	viability	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.7306689606907163	[378]	[115,271,203]	7	hSpCas9	negative selection	826299
1000593	1000616	4	+	26627737	DLD1	viability	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	2.262317880767535	[12]	[0,30,25]	9	hSpCas9	negative selection	826321
1000910	1000933	4	-	26627737	DLD1	viability	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.07034068658953685	[722]	[259,231,221]	0	hSpCas9	negative selection	826322
1001492	1001515	4	+	26627737	DLD1	viability	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.6790819355884792	[1316]	[740,720,536]	6	hSpCas9	negative selection	826323
1002430	1002453	4	+	26627737	DLD1	viability	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	0.4518297227219472	[446]	[99,282,193]	4	hSpCas9	negative selection	826325
987209	987232	4	-	26627737	GBM cells	viability after 5 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.35347973835116675	[80]	[52,57]	5	hSpCas9	negative selection	908613
987827	987850	4	-	26627737	GBM cells	viability after 5 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.12808482885319541	[272]	[182,136]	2	hSpCas9	negative selection	908614
1000593	1000616	4	+	26627737	GBM cells	viability after 5 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-2.101086125114315	[11]	[0,1]	-9	hSpCas9	negative selection	908636
1000910	1000933	4	-	26627737	GBM cells	viability after 5 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.41198345712505624	[479]	[332,351]	6	hSpCas9	negative selection	908637
1001492	1001515	4	+	26627737	GBM cells	viability after 5 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	-0.35110966542795286	[860]	[333,389]	-5	hSpCas9	negative selection	908638
1002430	1002453	4	+	26627737	GBM cells	viability after 5 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	0.6358794690518916	[161]	[109,159]	8	hSpCas9	negative selection	908640
987209	987232	4	-	26627737	GBM cells	viability after 13 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.764977005567832	[80]	[61,84]	8	hSpCas9	negative selection	990928
987827	987850	4	-	26627737	GBM cells	viability after 13 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.026907451599671367	[272]	[183,123]	0	hSpCas9	negative selection	990929
1000593	1000616	4	+	26627737	GBM cells	viability after 13 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-2.702859377142709	[11]	[0,0]	-9	hSpCas9	negative selection	990951
1000910	1000933	4	-	26627737	GBM cells	viability after 13 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.056225943511982956	[479]	[331,220]	0	hSpCas9	negative selection	990952
1001492	1001515	4	+	26627737	GBM cells	viability after 13 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	-0.12372395998340968	[860]	[516,356]	-1	hSpCas9	negative selection	990953
1002430	1002453	4	+	26627737	GBM cells	viability after 13 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	0.6830828914668238	[161]	[187,102]	8	hSpCas9	negative selection	990955
987209	987232	4	-	26627737	GBM cells	viability after 21 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.8276339399856509	[80]	[63,90]	7	hSpCas9	negative selection	1073243
987827	987850	4	-	26627737	GBM cells	viability after 21 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	-0.031509661200075575	[272]	[165,125]	0	hSpCas9	negative selection	1073244
1000593	1000616	4	+	26627737	GBM cells	viability after 21 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-2.704729201105498	[11]	[0,0]	-9	hSpCas9	negative selection	1073266
1000910	1000933	4	-	26627737	GBM cells	viability after 21 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	-0.39333911344733585	[479]	[220,177]	-4	hSpCas9	negative selection	1073267
1001492	1001515	4	+	26627737	GBM cells	viability after 21 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	-0.5917030242694694	[860]	[312,307]	-5	hSpCas9	negative selection	1073268
1002430	1002453	4	+	26627737	GBM cells	viability after 21 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	0.47623588185417287	[161]	[123,120]	5	hSpCas9	negative selection	1073270
987209	987232	4	-	26627737	RPE1	viability after 9 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.008157409507011604	[290]	[88,94]	0	hSpCas9	negative selection	1155558
987827	987850	4	-	26627737	RPE1	viability after 9 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	1.310881510323048	[513]	[355,454]	7	hSpCas9	negative selection	1155559
1000593	1000616	4	+	26627737	RPE1	viability after 9 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-5.10591318320984	[109]	[0,0]	-9	hSpCas9	negative selection	1155581
1000910	1000933	4	-	26627737	RPE1	viability after 9 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	-0.5209579276953057	[1635]	[359,352]	-4	hSpCas9	negative selection	1155582
1001492	1001515	4	+	26627737	RPE1	viability after 9 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.17080087521271525	[2593]	[873,965]	1	hSpCas9	negative selection	1155583
1002430	1002453	4	+	26627737	RPE1	viability after 9 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	0.19765095018823492	[835]	[221,400]	1	hSpCas9	negative selection	1155585
987209	987232	4	-	26627737	RPE1	viability after 12 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.3596193327006425	[290]	[110,88]	2	hSpCas9	negative selection	1237873
987827	987850	4	-	26627737	RPE1	viability after 12 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	1.5525702602292961	[513]	[526,275]	8	hSpCas9	negative selection	1237874
1000593	1000616	4	+	26627737	RPE1	viability after 12 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-4.885248301851522	[109]	[0,0]	-9	hSpCas9	negative selection	1237896
1000910	1000933	4	-	26627737	RPE1	viability after 12 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	-0.5845261481238622	[1635]	[381,198]	-4	hSpCas9	negative selection	1237897
1001492	1001515	4	+	26627737	RPE1	viability after 12 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.3538750124981773	[2593]	[759,1028]	2	hSpCas9	negative selection	1237898
1002430	1002453	4	+	26627737	RPE1	viability after 12 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	-0.21090999379967268	[835]	[212,173]	-1	hSpCas9	negative selection	1237900
987209	987232	4	-	26627737	RPE1	viability after 15 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	-0.1176060268903707	[290]	[82,68]	0	hSpCas9	negative selection	1320188
987827	987850	4	-	26627737	RPE1	viability after 15 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	1.6543157702047915	[513]	[531,385]	8	hSpCas9	negative selection	1320189
1000593	1000616	4	+	26627737	RPE1	viability after 15 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-4.959610839652766	[109]	[0,0]	-9	hSpCas9	negative selection	1320211
1000910	1000933	4	-	26627737	RPE1	viability after 15 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	-0.017429476672350175	[1635]	[612,306]	0	hSpCas9	negative selection	1320212
1001492	1001515	4	+	26627737	RPE1	viability after 15 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.21455682826514622	[2593]	[741,956]	1	hSpCas9	negative selection	1320213
1002430	1002453	4	+	26627737	RPE1	viability after 15 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	0.014163578230715346	[835]	[248,228]	0	hSpCas9	negative selection	1320215
987209	987232	4	-	26627737	RPE1	viability after 18 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.3804991673147198	[290]	[108,94]	2	hSpCas9	negative selection	1402503
987827	987850	4	-	26627737	RPE1	viability after 18 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	1.3264369648176166	[513]	[445,242]	7	hSpCas9	negative selection	1402504
1000593	1000616	4	+	26627737	RPE1	viability after 18 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-4.891691453423917	[109]	[0,0]	-9	hSpCas9	negative selection	1402526
1000910	1000933	4	-	26627737	RPE1	viability after 18 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	-0.4239294105042106	[1635]	[462,185]	-3	hSpCas9	negative selection	1402527
1001492	1001515	4	+	26627737	RPE1	viability after 18 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.20078583451429632	[2593]	[864,739]	1	hSpCas9	negative selection	1402528
1002430	1002453	4	+	26627737	RPE1	viability after 18 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	-0.058694115371898094	[835]	[219,212]	0	hSpCas9	negative selection	1402530
987209	987232	4	-	26627737	HeLa	viability after 8 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.06924800394806918	[291]	[60,159,160]	0	hSpCas9	negative selection	1484818
987827	987850	4	-	26627737	HeLa	viability after 8 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.6518265446342515	[333]	[186,231,254]	5	hSpCas9	negative selection	1484819
1000593	1000616	4	+	26627737	HeLa	viability after 8 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-4.47445344777498	[68]	[0,1,0]	-9	hSpCas9	negative selection	1484841
1000910	1000933	4	-	26627737	HeLa	viability after 8 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.006788480782014661	[810]	[396,261,409]	0	hSpCas9	negative selection	1484842
1001492	1001515	4	+	26627737	HeLa	viability after 8 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.15956881361317854	[1116]	[546,634,453]	1	hSpCas9	negative selection	1484843
1002430	1002453	4	+	26627737	HeLa	viability after 8 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	2.3721963286674113	[78]	[325,69,170]	9	hSpCas9	negative selection	1484845
987209	987232	4	-	26627737	HeLa	viability after 12 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	-0.12287301730831562	[291]	[210,19,113]	-1	hSpCas9	negative selection	1567133
987827	987850	4	-	26627737	HeLa	viability after 12 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	1.0238201358281998	[333]	[34,514,259]	7	hSpCas9	negative selection	1567134
1000593	1000616	4	+	26627737	HeLa	viability after 12 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-2.3296227248387273	[68]	[0,13,0]	-9	hSpCas9	negative selection	1567156
1000910	1000933	4	-	26627737	HeLa	viability after 12 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.10750582175909118	[810]	[263,402,408]	1	hSpCas9	negative selection	1567157
1001492	1001515	4	+	26627737	HeLa	viability after 12 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.29583430917591613	[1116]	[640,577,481]	2	hSpCas9	negative selection	1567158
1002430	1002453	4	+	26627737	HeLa	viability after 12 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	2.692575225801669	[78]	[410,125,110]	9	hSpCas9	negative selection	1567160
987209	987232	4	-	26627737	HeLa	viability after 15 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	-0.8572980850465508	[291]	[79,46,69]	-6	hSpCas9	negative selection	1649448
987827	987850	4	-	26627737	HeLa	viability after 15 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.6527628378776155	[333]	[97,207,346]	5	hSpCas9	negative selection	1649449
1000593	1000616	4	+	26627737	HeLa	viability after 15 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-4.811991344470163	[68]	[0,0,0]	-9	hSpCas9	negative selection	1649471
1000910	1000933	4	-	26627737	HeLa	viability after 15 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.30822753439820105	[810]	[327,338,572]	2	hSpCas9	negative selection	1649472
1001492	1001515	4	+	26627737	HeLa	viability after 15 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	-0.03436538855325999	[1116]	[377,473,483]	0	hSpCas9	negative selection	1649473
1002430	1002453	4	+	26627737	HeLa	viability after 15 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	2.415033195277094	[78]	[260,85,165]	9	hSpCas9	negative selection	1649475
987209	987232	4	-	26627737	HeLa	viability after 18 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	-0.9364173332180334	[291]	[49,34,69]	-7	hSpCas9	negative selection	1731763
987827	987850	4	-	26627737	HeLa	viability after 18 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.6550568653616843	[333]	[60,178,346]	5	hSpCas9	negative selection	1731764
1000593	1000616	4	+	26627737	HeLa	viability after 18 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-4.501785692816297	[68]	[0,0,0]	-9	hSpCas9	negative selection	1731786
1000910	1000933	4	-	26627737	HeLa	viability after 18 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.29649964712368826	[810]	[214,278,572]	2	hSpCas9	negative selection	1731787
1001492	1001515	4	+	26627737	HeLa	viability after 18 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	-0.03205058126548632	[1116]	[264,379,483]	0	hSpCas9	negative selection	1731788
1002430	1002453	4	+	26627737	HeLa	viability after 18 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	2.433547412196394	[78]	[173,77,165]	9	hSpCas9	negative selection	1731790
987209	987232	4	-	26627737	HCT116	viability after 6 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.3052731599860803	[239]	[54,41]	1	hSpCas9	negative selection	1814078
987827	987850	4	-	26627737	HCT116	viability after 6 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	2.4329649670409546	[317]	[122,350]	9	hSpCas9	negative selection	1814079
1000593	1000616	4	+	26627737	HCT116	viability after 6 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-3.8543016988694454	[91]	[0,0]	-9	hSpCas9	negative selection	1814101
1000910	1000933	4	-	26627737	HCT116	viability after 6 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.004056712237026305	[1237]	[238,170]	0	hSpCas9	negative selection	1814102
1001492	1001515	4	+	26627737	HCT116	viability after 6 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	-0.9972670628436618	[2152]	[311,90]	-5	hSpCas9	negative selection	1814103
1002430	1002453	4	+	26627737	HCT116	viability after 6 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	-0.49198389000599285	[383]	[98,11]	-3	hSpCas9	negative selection	1814105
987209	987232	4	-	26627737	HCT116	viability after 8 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.3234969718962404	[126]	[58,98,103]	3	hSpCas9	negative selection	1896393
987827	987850	4	-	26627737	HCT116	viability after 8 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.5926749685875274	[327]	[365,234,218]	6	hSpCas9	negative selection	1896394
1000593	1000616	4	+	26627737	HCT116	viability after 8 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	4.599703078980409	[0]	[0,36,1]	9	hSpCas9	negative selection	1896416
1000910	1000933	4	-	26627737	HCT116	viability after 8 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.4737508025620414	[538]	[299,493,440]	5	hSpCas9	negative selection	1896417
1001492	1001515	4	+	26627737	HCT116	viability after 8 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.309232333111259	[706]	[549,390,507]	3	hSpCas9	negative selection	1896418
1002430	1002453	4	+	26627737	HCT116	viability after 8 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	0.17218506350820229	[279]	[235,141,144]	2	hSpCas9	negative selection	1896420
987209	987232	4	-	26627737	HCT116	viability after 9 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	1.7944458136259662	[239]	[166,265]	9	hSpCas9	negative selection	1978708
987827	987850	4	-	26627737	HCT116	viability after 9 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	2.3935603443832183	[317]	[248,601]	9	hSpCas9	negative selection	1978709
1000593	1000616	4	+	26627737	HCT116	viability after 9 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-4.618572144703545	[91]	[0,0]	-9	hSpCas9	negative selection	1978731
1000910	1000933	4	-	26627737	HCT116	viability after 9 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	-0.249771212752805	[1237]	[377,198]	-2	hSpCas9	negative selection	1978732
1001492	1001515	4	+	26627737	HCT116	viability after 9 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	-0.4406944761751279	[2152]	[379,457]	-3	hSpCas9	negative selection	1978733
1002430	1002453	4	+	26627737	HCT116	viability after 9 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	-0.27886255107159674	[383]	[174,12]	-2	hSpCas9	negative selection	1978735
987209	987232	4	-	26627737	HCT116	viability after 12 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.1738166193438031	[126]	[34,99,94]	1	hSpCas9	negative selection	2061023
987827	987850	4	-	26627737	HCT116	viability after 12 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.5191114789690694	[327]	[342,261,127]	5	hSpCas9	negative selection	2061024
1000593	1000616	4	+	26627737	HCT116	viability after 12 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	3.1339524502100655	[0]	[3,8,0]	9	hSpCas9	negative selection	2061046
1000910	1000933	4	-	26627737	HCT116	viability after 12 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.3267882269840292	[538]	[272,353,445]	3	hSpCas9	negative selection	2061047
1001492	1001515	4	+	26627737	HCT116	viability after 12 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	-0.1084135211337447	[706]	[340,415,278]	-1	hSpCas9	negative selection	2061048
1002430	1002453	4	+	26627737	HCT116	viability after 12 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	-0.41811684516636605	[279]	[65,140,127]	-4	hSpCas9	negative selection	2061050
987209	987232	4	-	26627737	HCT116	viability after 15 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.7599965567076766	[126]	[127,111,130]	6	hSpCas9	negative selection	2143338
987827	987850	4	-	26627737	HCT116	viability after 15 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.5023129497354939	[327]	[387,142,283]	5	hSpCas9	negative selection	2143339
1000593	1000616	4	+	26627737	HCT116	viability after 15 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	6.520170411669224	[0]	[29,124,0]	9	hSpCas9	negative selection	2143361
1000910	1000933	4	-	26627737	HCT116	viability after 15 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.12567518549607037	[538]	[262,397,342]	1	hSpCas9	negative selection	2143362
1001492	1001515	4	+	26627737	HCT116	viability after 15 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.31428674481414043	[706]	[735,493,314]	3	hSpCas9	negative selection	2143363
1002430	1002453	4	+	26627737	HCT116	viability after 15 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	0.10826816669828995	[279]	[90,163,253]	1	hSpCas9	negative selection	2143365
987209	987232	4	-	26627737	HCT116	viability after 18 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	-0.7265301732245304	[126]	[17,21,73]	-6	hSpCas9	negative selection	2225653
987827	987850	4	-	26627737	HCT116	viability after 18 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	1.133351440431073	[327]	[377,288,381]	8	hSpCas9	negative selection	2225654
1000593	1000616	4	+	26627737	HCT116	viability after 18 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	5.024381988504746	[0]	[4,38,0]	9	hSpCas9	negative selection	2225676
1000910	1000933	4	-	26627737	HCT116	viability after 18 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.02804228195922087	[538]	[186,332,272]	0	hSpCas9	negative selection	2225677
1001492	1001515	4	+	26627737	HCT116	viability after 18 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.3327185661580898	[706]	[547,393,347]	3	hSpCas9	negative selection	2225678
1002430	1002453	4	+	26627737	HCT116	viability after 18 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	0.047613405276820724	[279]	[15,196,205]	0	hSpCas9	negative selection	2225680
993523	993546	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCGGGAGTTGAACTGTAATCAGG	IDUA	ENSG00000127415	-0.25554899310151846	[249,305]	[24,78]	-1	dCas9-VP64	positive selection	2454056
993573	993596	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGGCTGGGAGCTCCTCAGAGG	IDUA	ENSG00000127415	1.0587427480042877	[18,51]	[7,24]	4	dCas9-VP64	positive selection	2454057
993549	993572	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGTAGGAGTTAGAGCTGTGTGG	IDUA	ENSG00000127415	2.1799385615558045	[165,319]	[163,329]	7	dCas9-VP64	positive selection	2454058
993523	993546	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCGGGAGTTGAACTGTAATCAGG	IDUA	ENSG00000127415	0.622214704735855	[135,184]	[80,79]	4	dCas9-VP64	positive selection	2549311
993573	993596	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGGCTGGGAGCTCCTCAGAGG	IDUA	ENSG00000127415	-0.9601161350557419	[291,71]	[48,12]	-8	dCas9-VP64	positive selection	2549312
993549	993572	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGTAGGAGTTAGAGCTGTGTGG	IDUA	ENSG00000127415	1.2416478221947855	[172,452]	[343,142]	7	dCas9-VP64	positive selection	2549313
1001478	1001501	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACTGGCGCATGTTTCCAAGTGG	IDUA	ENSG00000127415	-0.16783213309236494	[2,3]	[2,2]	-2	hSpCas9	positive selection	2994744
987209	987232	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.38995922979505204	[2,2]	[3,2]	7	hSpCas9	positive selection	2994745
987869	987892	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.39284982196382856	[2,2]	[4,1]	7	hSpCas9	positive selection	2994746
987880	987903	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGGGCGCCGTCCCTCACCGCGG	IDUA	ENSG00000127415	0.0011372319470621117	[3,2]	[0,3]	0	hSpCas9	positive selection	2994747
1001478	1001501	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACTGGCGCATGTTTCCAAGTGG	IDUA	ENSG00000127415	-0.008360240605711222	[2,2]	[3,0]	0	hSpCas9	positive selection	3062602
987209	987232	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.37909576462720057	[2,2]	[2,2]	6	hSpCas9	positive selection	3062603
987869	987892	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	-0.5407558480698825	[2,2]	[1,0]	-7	hSpCas9	positive selection	3062604
987880	987903	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGGGCGCCGTCCCTCACCGCGG	IDUA	ENSG00000127415	-0.370524977107783	[3,3]	[1,0]	-5	hSpCas9	positive selection	3062605
1002019	1002042		+	24336571	A375	resistance to PLX after 7 days	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.17897868958797733	[18,12]	[13,13]	-5	hSpCas9	positive selection	3120327
1002065	1002088		+	24336571	A375	resistance to PLX after 7 days	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	-0.08986987397371671	[6,8]	[7,6]	-3	hSpCas9	positive selection	3120328
1000633	1000656		+	24336571	A375	resistance to PLX after 7 days	GAGCTACAACTTCACCCACCTGG	IDUA	ENSG00000127415	-0.1630032201309226	[24,22]	[19,21]	-5	hSpCas9	positive selection	3120329
1002070	1002093		-	24336571	A375	resistance to PLX after 7 days	GTCCGCCTCGTCGTTGTAAATGG	IDUA	ENSG00000127415	-0.22017483651504305	[13,14]	[12,10]	-6	hSpCas9	positive selection	3120330
1002019	1002042		+	24336571	A375	resistance to PLX after 14 days	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.8943543010294459	[10,8]	[6,9]	7	hSpCas9	positive selection	3178120
1002065	1002088		+	24336571	A375	resistance to PLX after 14 days	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.2427350510403692	[4,4]	[2,2]	2	hSpCas9	positive selection	3178121
1000633	1000656		+	24336571	A375	resistance to PLX after 14 days	GAGCTACAACTTCACCCACCTGG	IDUA	ENSG00000127415	-0.38834903745373794	[29,19]	[8,7]	-4	hSpCas9	positive selection	3178122
1002070	1002093		-	24336571	A375	resistance to PLX after 14 days	GTCCGCCTCGTCGTTGTAAATGG	IDUA	ENSG00000127415	-0.8603554238110449	[15,14]	[2,3]	-8	hSpCas9	positive selection	3178123
1002019	1002042		+	24336571	A375	viability after 7 days	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.3231760321957838	[12]	[18,12]	5	hSpCas9	negative selection	3235913
1002065	1002088		+	24336571	A375	viability after 7 days	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	-0.9089919592001632	[15]	[6,8]	-8	hSpCas9	negative selection	3235914
1000633	1000656		+	24336571	A375	viability after 7 days	GAGCTACAACTTCACCCACCTGG	IDUA	ENSG00000127415	0.14333507052655936	[22]	[24,22]	2	hSpCas9	negative selection	3235915
1002070	1002093		-	24336571	A375	viability after 7 days	GTCCGCCTCGTCGTTGTAAATGG	IDUA	ENSG00000127415	0.18644229979424995	[12]	[13,14]	3	hSpCas9	negative selection	3235916
1002019	1002042		+	24336571	A375	viability after 14 days	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.28989905650434417	[12]	[10,8]	-3	hSpCas9	negative selection	3293706
1002065	1002088		+	24336571	A375	viability after 14 days	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	-1.4663839444874738	[15]	[4,4]	-9	hSpCas9	negative selection	3293707
1000633	1000656		+	24336571	A375	viability after 14 days	GAGCTACAACTTCACCCACCTGG	IDUA	ENSG00000127415	0.23205135834218427	[22]	[29,19]	3	hSpCas9	negative selection	3293708
1002070	1002093		-	24336571	A375	viability after 14 days	GTCCGCCTCGTCGTTGTAAATGG	IDUA	ENSG00000127415	0.28462930818166715	[12]	[15,14]	3	hSpCas9	negative selection	3293709
1003081	1003104	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.5755638027189065	[227,227]	[0,0]	-4	hSpCas9	positive selection	3373705
1000617	1000640	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	0.21293209208738176	[131,131]	[0,0]	1	hSpCas9	positive selection	3373706
1000651	1000674	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.38652997832888963	[199,199]	[0,0]	-2	hSpCas9	positive selection	3373707
1001477	1001500	4	+	26780180	HT29	viability (Avana library 4 designs)	GACTGGCGCATGTTTCCAAGTGG	IDUA	ENSG00000127415	1.03818052483602	[]	[]	4	hSpCas9	negative selection	3432084
987209	987232	4	-	26780180	HT29	viability (Avana library 4 designs)	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	1.20153551890367	[]	[]	5	hSpCas9	negative selection	3432085
987869	987892	4	-	26780180	HT29	viability (Avana library 4 designs)	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	1.13144421325056	[]	[]	4	hSpCas9	negative selection	3432086
987879	987902	4	+	26780180	HT29	viability (Avana library 4 designs)	GTGGGCGCCGTCCCTCACCGCGG	IDUA	ENSG00000127415	-0.0899133893416896	[]	[]	-1	hSpCas9	negative selection	3432087
987209	987232	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	4.42781073142113	[]	[]	7	hSpCas9	negative selection	3518060
987869	987892	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	4.54229820235946	[]	[]	7	hSpCas9	negative selection	3518061
1001477	1001500	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACTGGCGCATGTTTCCAAGTGG	IDUA	ENSG00000127415	5.39268899002013	[]	[]	8	hSpCas9	negative selection	3518062
987879	987902	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTGGGCGCCGTCCCTCACCGCGG	IDUA	ENSG00000127415	4.5256340485817	[]	[]	7	hSpCas9	negative selection	3518063
1000903	1000926	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	1.6115183867855	[]	[]	2	hSpCas9	negative selection	3518064
1001526	1001549	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGACGTTGTCAAAGTCGTGGTGG	IDUA	ENSG00000127415	-4.54988190901285	[]	[]	-5	hSpCas9	negative selection	3518065
987209	987232	4	-	26780180	A375	viability (Avana lentiGuide)	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	-3.51463986484265	[]	[]	-6	hSpCas9	negative selection	3626719
987869	987892	4	-	26780180	A375	viability (Avana lentiGuide)	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	9.73618025668905	[]	[]	6	hSpCas9	negative selection	3626720
1001477	1001500	4	+	26780180	A375	viability (Avana lentiGuide)	GACTGGCGCATGTTTCCAAGTGG	IDUA	ENSG00000127415	1.89623931716994	[]	[]	2	hSpCas9	negative selection	3626721
987879	987902	4	+	26780180	A375	viability (Avana lentiGuide)	GTGGGCGCCGTCCCTCACCGCGG	IDUA	ENSG00000127415	7.61392654293816	[]	[]	6	hSpCas9	negative selection	3626722
1000903	1000926	4	-	26780180	A375	viability (Avana lentiGuide)	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	2.11246629199529	[]	[]	2	hSpCas9	negative selection	3626723
1001526	1001549	4	-	26780180	A375	viability (Avana lentiGuide)	AGACGTTGTCAAAGTCGTGGTGG	IDUA	ENSG00000127415	3.33074244446732	[]	[]	3	hSpCas9	negative selection	3626724
987209	987232	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	-0.05034710262703396	[3]	[4,3]	-1	hSpCas9	positive selection	3735378
987869	987892	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.08578080484995601	[4]	[5,3]	2	hSpCas9	positive selection	3735379
1001477	1001500	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACTGGCGCATGTTTCCAAGTGG	IDUA	ENSG00000127415	0.28097633274896117	[4]	[5,4]	7	hSpCas9	positive selection	3735380
987879	987902	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGGGCGCCGTCCCTCACCGCGG	IDUA	ENSG00000127415	0.22510507506319857	[4]	[6,4]	6	hSpCas9	positive selection	3735381
1000903	1000926	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.16034536974712338	[5]	[6,5]	4	hSpCas9	positive selection	3735382
1001526	1001549	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGACGTTGTCAAAGTCGTGGTGG	IDUA	ENSG00000127415	-0.4450852700476051	[1]	[0,0]	-6	hSpCas9	positive selection	3735383
987209	987232	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.21957291555473726	[4]	[5,4]	5	hSpCas9	positive selection	3843985
987869	987892	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	-0.6988266573457295	[4]	[2,1]	-7	hSpCas9	positive selection	3843986
1001477	1001500	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACTGGCGCATGTTTCCAAGTGG	IDUA	ENSG00000127415	0.1021178724137719	[5]	[4,4]	2	hSpCas9	positive selection	3843987
987879	987902	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGGGCGCCGTCCCTCACCGCGG	IDUA	ENSG00000127415	-0.025082353465610913	[4]	[4,2]	0	hSpCas9	positive selection	3843988
1000903	1000926	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.1533296260642246	[6]	[5,6]	3	hSpCas9	positive selection	3843989
1001526	1001549	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGACGTTGTCAAAGTCGTGGTGG	IDUA	ENSG00000127415	-1.1842616456956205	[1]	[0,0]	-9	hSpCas9	positive selection	3843990
1002019	1002042	4	+	26780180	A375	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	1.32007943357722	[]	[]	7	hSpCas9	negative selection	3949967
1002065	1002088	4	+	26780180	A375	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	1.28125431873974	[]	[]	7	hSpCas9	negative selection	3949968
1003081	1003104	4	-	26780180	A375	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	1.03028628409924	[]	[]	5	hSpCas9	negative selection	3949969
1000651	1000674	4	-	26780180	A375	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	1.47404692075201	[]	[]	8	hSpCas9	negative selection	3949970
1003040	1003063	4	+	26780180	A375	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.792724542862508	[]	[]	3	hSpCas9	negative selection	3949971
1000617	1000640	4	-	26780180	A375	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	1.61828636217951	[]	[]	8	hSpCas9	negative selection	3949972
1002019	1002042	4	+	26780180	HT29	viability (GeCKOv2 library)	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	1.01290276291128	[]	[]	4	hSpCas9	negative selection	4057933
1002065	1002088	4	+	26780180	HT29	viability (GeCKOv2 library)	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	-0.138809928691897	[]	[]	-4	hSpCas9	negative selection	4057934
1003081	1003104	4	-	26780180	HT29	viability (GeCKOv2 library)	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	0.266449239479473	[]	[]	0	hSpCas9	negative selection	4057935
1000651	1000674	4	-	26780180	HT29	viability (GeCKOv2 library)	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	1.55838494783299	[]	[]	8	hSpCas9	negative selection	4057936
1003040	1003063	4	+	26780180	HT29	viability (GeCKOv2 library)	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	1.52314565460316	[]	[]	7	hSpCas9	negative selection	4057937
1000617	1000640	4	-	26780180	HT29	viability (GeCKOv2 library)	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	2.21822846567393	[]	[]	9	hSpCas9	negative selection	4057938
1002019	1002042	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.20414111958145537	[4]	[1,3]	-5	hSpCas9	positive selection	4143917
1002065	1002088	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	-0.26993838753451904	[2]	[1,1]	-6	hSpCas9	positive selection	4143918
1000633	1000656	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGCTACAACTTCACCCACCTGG	IDUA	ENSG00000127415	-0.12532721637684657	[4]	[2,3]	-3	hSpCas9	positive selection	4143919
1002070	1002093	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCCGCCTCGTCGTTGTAAATGG	IDUA	ENSG00000127415	-0.18020418411043593	[3]	[2,1]	-4	hSpCas9	positive selection	4143920
991138	991161	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCGCCCTCACGCTGATGACCGG	IDUA	ENSG00000127415	0.05393442535384946	[5]	[3,3]	1	hSpCas9	positive selection	4171052
989309	989332	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	0.49817210960066405	[1]	[1,0]	9	hSpCas9	positive selection	4171054
991496	991519	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.2272640573070263	[3]	[2,3]	6	hSpCas9	positive selection	4171056
991515	991538	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.21073586750193618	[4]	[2,3]	5	hSpCas9	positive selection	4171057
1002019	1002042	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-1.0115490118225263	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4207939
1002065	1002088	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	-0.22770874427780236	[3]	[1,0,0,0]	-3	hSpCas9	positive selection	4207940
1000633	1000656	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGCTACAACTTCACCCACCTGG	IDUA	ENSG00000127415	-0.17794153007540592	[4]	[3,0,1,0]	-3	hSpCas9	positive selection	4207941
1002070	1002093	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCCGCCTCGTCGTTGTAAATGG	IDUA	ENSG00000127415	-0.2579165420075798	[3]	[3,0,0,0]	-4	hSpCas9	positive selection	4207942
991138	991161	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCGCCCTCACGCTGATGACCGG	IDUA	ENSG00000127415	1.2999758177417051	[4]	[3,4,2,5]	9	hSpCas9	positive selection	4235074
989309	989332	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	-0.4827380929436638	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4235076
991496	991519	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.05630645683881352	[4]	[0,3,3,0]	0	hSpCas9	positive selection	4235078
991515	991538	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.32449706926000366	[4]	[2,3,5,0]	2	hSpCas9	positive selection	4235079
1002019	1002042	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.41541167201992085	[3]	[2,0]	-7	hSpCas9	positive selection	4276248
1003040	1003063	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.022777086144798543	[3]	[2,2]	0	hSpCas9	positive selection	4276249
1002065	1002088	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.4259337058588781	[3]	[3,3]	8	hSpCas9	positive selection	4276250
989309	989332	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	-0.2541754339458533	[0]	[0,0]	-5	hSpCas9	positive selection	4298410
991515	991538	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.7704541081572275	[3]	[3,5]	9	hSpCas9	positive selection	4298411
990146	990169	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.1797397356023699	[3]	[3,1]	-4	hSpCas9	positive selection	4298412
1003081	1003104	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	0.2392563577994186	[3]	[3,3]	5	hSpCas9	positive selection	4340506
1000617	1000640	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.10371488508973889	[2]	[2,1]	-2	hSpCas9	positive selection	4340507
1000651	1000674	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.16015659270871202	[3]	[2,1]	-3	hSpCas9	positive selection	4340508
991496	991519	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.05797689171130249	[1]	[0,0]	-1	hSpCas9	positive selection	4362664
987869	987891	4	-	27760321	OCIAML3	viability	GACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.17584566652161115	[601,474]	[394,573]	2	hSpCas9	negative selection	4408726
1001691	1001713	4	+	27760321	OCIAML3	viability	ACTACGATGCCTGCTCGGAGGG	IDUA	ENSG00000127415	-0.22871371501465754	[682,561]	[304,554]	-2	hSpCas9	negative selection	4408727
1001806	1001828	4	-	27760321	OCIAML3	viability	GTTGGTACCGTCGTGGCAGTGG	IDUA	ENSG00000127415	0.35400406951174324	[539,538]	[517,570]	4	hSpCas9	negative selection	4408728
1002052	1002074	4	-	27760321	OCIAML3	viability	ATGGGGGTGTCCGCGAACTTGG	IDUA	ENSG00000127415	0.4076856255668575	[732,604]	[574,841]	5	hSpCas9	negative selection	4408729
1002078	1002100	4	+	27760321	OCIAML3	viability	AACGACGAGGCGGACCCGCTGG	IDUA	ENSG00000127415	0.5537133407848387	[742,580]	[621,927]	6	hSpCas9	negative selection	4408730
987869	987891	4	-	27760321	OCIAML2	viability	GACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.16322367828264972	[601,474]	[425,561]	2	hSpCas9	negative selection	4492189
1001691	1001713	4	+	27760321	OCIAML2	viability	ACTACGATGCCTGCTCGGAGGG	IDUA	ENSG00000127415	0.27857101852306204	[682,561]	[528,711]	3	hSpCas9	negative selection	4492190
1001806	1001828	4	-	27760321	OCIAML2	viability	GTTGGTACCGTCGTGGCAGTGG	IDUA	ENSG00000127415	-0.040758631556655156	[539,538]	[394,465]	0	hSpCas9	negative selection	4492191
1002052	1002074	4	-	27760321	OCIAML2	viability	ATGGGGGTGTCCGCGAACTTGG	IDUA	ENSG00000127415	0.7124751460550445	[732,604]	[792,1000]	8	hSpCas9	negative selection	4492192
1002078	1002100	4	+	27760321	OCIAML2	viability	AACGACGAGGCGGACCCGCTGG	IDUA	ENSG00000127415	-0.07442174941747437	[742,580]	[417,619]	-1	hSpCas9	negative selection	4492193
987869	987891	4	-	27760321	MV411	viability	GACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.06018866764479919	[601,474]	[519,139]	0	hSpCas9	negative selection	4575652
1001691	1001713	4	+	27760321	MV411	viability	ACTACGATGCCTGCTCGGAGGG	IDUA	ENSG00000127415	1.0649268677667487	[682,561]	[1049,562]	7	hSpCas9	negative selection	4575653
1001806	1001828	4	-	27760321	MV411	viability	GTTGGTACCGTCGTGGCAGTGG	IDUA	ENSG00000127415	-0.834712038560309	[539,538]	[27,458]	-5	hSpCas9	negative selection	4575654
1002052	1002074	4	-	27760321	MV411	viability	ATGGGGGTGTCCGCGAACTTGG	IDUA	ENSG00000127415	0.3098018261271802	[732,604]	[451,683]	2	hSpCas9	negative selection	4575655
1002078	1002100	4	+	27760321	MV411	viability	AACGACGAGGCGGACCCGCTGG	IDUA	ENSG00000127415	-0.44546918565335847	[742,580]	[358,257]	-3	hSpCas9	negative selection	4575656
987869	987891	4	-	27760321	HL60	viability	GACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	-0.1984230396672489	[601,474]	[377,383]	-2	hSpCas9	negative selection	4659115
1001691	1001713	4	+	27760321	HL60	viability	ACTACGATGCCTGCTCGGAGGG	IDUA	ENSG00000127415	0.5053551130004277	[682,561]	[632,808]	6	hSpCas9	negative selection	4659116
1001806	1001828	4	-	27760321	HL60	viability	GTTGGTACCGTCGTGGCAGTGG	IDUA	ENSG00000127415	-0.19211725146394856	[539,538]	[419,351]	-2	hSpCas9	negative selection	4659117
1002052	1002074	4	-	27760321	HL60	viability	ATGGGGGTGTCCGCGAACTTGG	IDUA	ENSG00000127415	0.1400526995685506	[732,604]	[514,688]	1	hSpCas9	negative selection	4659118
1002078	1002100	4	+	27760321	HL60	viability	AACGACGAGGCGGACCCGCTGG	IDUA	ENSG00000127415	-0.282940080909593	[742,580]	[489,389]	-3	hSpCas9	negative selection	4659119
987869	987891	4	-	27760321	HT1080	viability	GACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	-0.38686242503811763	[474,370]	[20,246]	-2	hSpCas9	negative selection	4742578
1001691	1001713	4	+	27760321	HT1080	viability	ACTACGATGCCTGCTCGGAGGG	IDUA	ENSG00000127415	1.1928192076646402	[561,438]	[609,286]	6	hSpCas9	negative selection	4742579
1001806	1001828	4	-	27760321	HT1080	viability	GTTGGTACCGTCGTGGCAGTGG	IDUA	ENSG00000127415	0.45814984137562775	[538,420]	[403,107]	2	hSpCas9	negative selection	4742580
1002052	1002074	4	-	27760321	HT1080	viability	ATGGGGGTGTCCGCGAACTTGG	IDUA	ENSG00000127415	1.3140774279624476	[604,471]	[551,512]	7	hSpCas9	negative selection	4742581
1002078	1002100	4	+	27760321	HT1080	viability	AACGACGAGGCGGACCCGCTGG	IDUA	ENSG00000127415	-1.4500009035994261	[580,453]	[21,133]	-5	hSpCas9	negative selection	4742582
987869	987891	4	-	27760321	HT29	viability after 7 days	GACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	-0.058814666743805366	[474,370]	[553,517,498]	-1	hSpCas9	negative selection	4826041
1001691	1001713	4	+	27760321	HT29	viability after 7 days	ACTACGATGCCTGCTCGGAGGG	IDUA	ENSG00000127415	0.3872481269053956	[561,438]	[1016,759,773]	6	hSpCas9	negative selection	4826042
1001806	1001828	4	-	27760321	HT29	viability after 7 days	GTTGGTACCGTCGTGGCAGTGG	IDUA	ENSG00000127415	-0.6723390497289998	[538,420]	[384,422,353]	-7	hSpCas9	negative selection	4826043
1002052	1002074	4	-	27760321	HT29	viability after 7 days	ATGGGGGTGTCCGCGAACTTGG	IDUA	ENSG00000127415	0.11425558261336	[604,471]	[1167,522,619]	1	hSpCas9	negative selection	4826044
1002078	1002100	4	+	27760321	HT29	viability after 7 days	AACGACGAGGCGGACCCGCTGG	IDUA	ENSG00000127415	-0.3575973416775098	[580,453]	[423,770,353]	-5	hSpCas9	negative selection	4826045
987869	987891	4	-	27760321	HT29	viability after 25 days	GACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.16400961783222526	[474,370]	[511,528,589]	1	hSpCas9	negative selection	4909504
1001691	1001713	4	+	27760321	HT29	viability after 25 days	ACTACGATGCCTGCTCGGAGGG	IDUA	ENSG00000127415	0.6527322940424849	[561,438]	[817,937,950]	7	hSpCas9	negative selection	4909505
1001806	1001828	4	-	27760321	HT29	viability after 25 days	GTTGGTACCGTCGTGGCAGTGG	IDUA	ENSG00000127415	-0.37455924498256893	[538,420]	[547,314,394]	-4	hSpCas9	negative selection	4909506
1002052	1002074	4	-	27760321	HT29	viability after 25 days	ATGGGGGTGTCCGCGAACTTGG	IDUA	ENSG00000127415	0.1400973587589277	[604,471]	[531,725,796]	1	hSpCas9	negative selection	4909507
1002078	1002100	4	+	27760321	HT29	viability after 25 days	AACGACGAGGCGGACCCGCTGG	IDUA	ENSG00000127415	0.12977640024595982	[580,453]	[591,582,782]	1	hSpCas9	negative selection	4909508
987869	987891	4	-	27760321	HT29	viability after 22 days	GACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.20588649766148884	[474,370]	[506,586,599]	2	hSpCas9	negative selection	4992967
1001691	1001713	4	+	27760321	HT29	viability after 22 days	ACTACGATGCCTGCTCGGAGGG	IDUA	ENSG00000127415	0.4750883127272116	[561,438]	[857,688,864]	5	hSpCas9	negative selection	4992968
1001806	1001828	4	-	27760321	HT29	viability after 22 days	GTTGGTACCGTCGTGGCAGTGG	IDUA	ENSG00000127415	-0.6634776516563882	[538,420]	[265,367,419]	-5	hSpCas9	negative selection	4992969
1002052	1002074	4	-	27760321	HT29	viability after 22 days	ATGGGGGTGTCCGCGAACTTGG	IDUA	ENSG00000127415	-0.1374421350348427	[604,471]	[454,556,689]	-1	hSpCas9	negative selection	4992970
1002078	1002100	4	+	27760321	HT29	viability after 22 days	AACGACGAGGCGGACCCGCTGG	IDUA	ENSG00000127415	-0.13616784439594487	[580,453]	[346,386,907]	-1	hSpCas9	negative selection	4992971
987869	987891	4	-	27760321	HT29	viability after 19 days	GACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.09512282333027558	[474,370]	[480,488,573]	0	hSpCas9	negative selection	5076430
1001691	1001713	4	+	27760321	HT29	viability after 19 days	ACTACGATGCCTGCTCGGAGGG	IDUA	ENSG00000127415	0.65059181582188	[561,438]	[1111,690,913]	6	hSpCas9	negative selection	5076431
1001806	1001828	4	-	27760321	HT29	viability after 19 days	GTTGGTACCGTCGTGGCAGTGG	IDUA	ENSG00000127415	-0.32853792491698847	[538,420]	[506,251,554]	-3	hSpCas9	negative selection	5076432
1002052	1002074	4	-	27760321	HT29	viability after 19 days	ATGGGGGTGTCCGCGAACTTGG	IDUA	ENSG00000127415	0.6508208735004597	[604,471]	[774,1002,1096]	6	hSpCas9	negative selection	5076433
1002078	1002100	4	+	27760321	HT29	viability after 19 days	AACGACGAGGCGGACCCGCTGG	IDUA	ENSG00000127415	-0.49354172073174973	[580,453]	[405,581,276]	-4	hSpCas9	negative selection	5076434
987869	987891	4	-	27760321	HT29	viability after 16 days	GACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.09768666533667067	[474,370]	[711,300,530]	1	hSpCas9	negative selection	5159893
1001691	1001713	4	+	27760321	HT29	viability after 16 days	ACTACGATGCCTGCTCGGAGGG	IDUA	ENSG00000127415	0.5120246487142925	[561,438]	[808,820,765]	6	hSpCas9	negative selection	5159894
1001806	1001828	4	-	27760321	HT29	viability after 16 days	GTTGGTACCGTCGTGGCAGTGG	IDUA	ENSG00000127415	-0.5460054389555417	[538,420]	[407,376,321]	-5	hSpCas9	negative selection	5159895
1002052	1002074	4	-	27760321	HT29	viability after 16 days	ATGGGGGTGTCCGCGAACTTGG	IDUA	ENSG00000127415	0.2835502674410453	[604,471]	[800,472,938]	3	hSpCas9	negative selection	5159896
1002078	1002100	4	+	27760321	HT29	viability after 16 days	AACGACGAGGCGGACCCGCTGG	IDUA	ENSG00000127415	0.331260924041195	[580,453]	[735,652,798]	3	hSpCas9	negative selection	5159897
987869	987891	4	-	27760321	HT29	viability after 13 days	GACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.27251830940844113	[474,370]	[683,517,576]	3	hSpCas9	negative selection	5243356
1001691	1001713	4	+	27760321	HT29	viability after 13 days	ACTACGATGCCTGCTCGGAGGG	IDUA	ENSG00000127415	0.4685956272700516	[561,438]	[749,899,762]	6	hSpCas9	negative selection	5243357
1001806	1001828	4	-	27760321	HT29	viability after 13 days	GTTGGTACCGTCGTGGCAGTGG	IDUA	ENSG00000127415	-0.1725616117731426	[538,420]	[554,448,478]	-2	hSpCas9	negative selection	5243358
1002052	1002074	4	-	27760321	HT29	viability after 13 days	ATGGGGGTGTCCGCGAACTTGG	IDUA	ENSG00000127415	0.1708271208157207	[604,471]	[730,700,678]	2	hSpCas9	negative selection	5243359
1002078	1002100	4	+	27760321	HT29	viability after 13 days	AACGACGAGGCGGACCCGCTGG	IDUA	ENSG00000127415	0.23594537213984468	[580,453]	[553,613,938]	3	hSpCas9	negative selection	5243360
987869	987891	4	-	27760321	HT29	viability after 10 days	GACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.30056569274601375	[474,370]	[649,722,581]	4	hSpCas9	negative selection	5326819
1001691	1001713	4	+	27760321	HT29	viability after 10 days	ACTACGATGCCTGCTCGGAGGG	IDUA	ENSG00000127415	0.41886871249706464	[561,438]	[693,1013,803]	6	hSpCas9	negative selection	5326820
1001806	1001828	4	-	27760321	HT29	viability after 10 days	GTTGGTACCGTCGTGGCAGTGG	IDUA	ENSG00000127415	-0.22613906165149503	[538,420]	[449,558,528]	-3	hSpCas9	negative selection	5326821
1002052	1002074	4	-	27760321	HT29	viability after 10 days	ATGGGGGTGTCCGCGAACTTGG	IDUA	ENSG00000127415	0.5168214802755353	[604,471]	[815,931,1132]	7	hSpCas9	negative selection	5326822
1002078	1002100	4	+	27760321	HT29	viability after 10 days	AACGACGAGGCGGACCCGCTGG	IDUA	ENSG00000127415	0.2548515673708548	[580,453]	[696,724,886]	3	hSpCas9	negative selection	5326823
987869	987891	4	-	27760321	MOLM13	viability	GACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.667340860611444	[601,474]	[540,426]	4	hSpCas9	negative selection	5410282
1001691	1001713	4	+	27760321	MOLM13	viability	ACTACGATGCCTGCTCGGAGGG	IDUA	ENSG00000127415	0.4913814149295886	[682,561]	[653,352]	3	hSpCas9	negative selection	5410283
1001806	1001828	4	-	27760321	MOLM13	viability	GTTGGTACCGTCGTGGCAGTGG	IDUA	ENSG00000127415	0.07218237042961612	[539,538]	[165,452]	0	hSpCas9	negative selection	5410284
1002052	1002074	4	-	27760321	MOLM13	viability	ATGGGGGTGTCCGCGAACTTGG	IDUA	ENSG00000127415	0.3183414816057901	[732,604]	[582,370]	2	hSpCas9	negative selection	5410285
1002078	1002100	4	+	27760321	MOLM13	viability	AACGACGAGGCGGACCCGCTGG	IDUA	ENSG00000127415	0.13381100022461512	[742,580]	[251,538]	0	hSpCas9	negative selection	5410286
987389	987412	4	+	27661255	K562	viability	GGTGGGTCCTCCACCTGAGTGGG	IDUA	ENSG00000127415	0.12014448558264354	[624,658]	[646,479]	4	dCas9-KRAB	negative selection	5486088
987258	987281	4	-	27661255	K562	viability	GTGCGGCCAGGGGGTCCCGGAGG	IDUA	ENSG00000127415	-0.7306895546298704	[579,550]	[299,248]	-8	dCas9-KRAB	negative selection	5486089
987547	987570	4	-	27661255	K562	viability	GCGGGTACCTCAGCTCTAGGTGG	IDUA	ENSG00000127415	-0.08413987745016882	[398,480]	[364,300]	-3	dCas9-KRAB	negative selection	5486090
992946	992969	4	+	27661255	K562	viability	GTGTGCGAGCTCCAGTCTCCTGG	IDUA	ENSG00000127415	-0.03587836336092436	[736,787]	[587,597]	-1	dCas9-KRAB	negative selection	5511804
992960	992983	4	+	27661255	K562	viability	GTCTCCTGGCGGGTGTGTTGGGG	IDUA	ENSG00000127415	0.3026876381710948	[519,486]	[534,463]	8	dCas9-KRAB	negative selection	5511805
992981	993004	4	+	27661255	K562	viability	GGCAGTGAGCCCAGCCTGGTAGG	IDUA	ENSG00000127415	0.17353908586248487	[650,673]	[704,503]	6	dCas9-KRAB	negative selection	5511806
993306	993329	4	+	27661255	K562	viability	GGAGTCCTCACAGGCGCGGAGGG	IDUA	ENSG00000127415	-0.003284089515913191	[1013,1224]	[906,873]	0	dCas9-KRAB	negative selection	5511807
993324	993347	4	+	27661255	K562	viability	GAGGGCCCTGGGATGACGAGGGG	IDUA	ENSG00000127415	0.01275158566856227	[896,976]	[882,643]	0	dCas9-KRAB	negative selection	5511808
992940	992963	4	-	27661255	K562	viability	GACTGGAGCTCGCACACCCTGGG	IDUA	ENSG00000127415	0.12193748447361033	[665,579]	[557,529]	4	dCas9-KRAB	negative selection	5511809
1002019	1002042	4	+	27260156	BXPC3	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.19773837634723013	[667]	[757,894,704,842]	4	hSpCas9	negative selection	5548708
1003040	1003063	4	+	27260156	BXPC3	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.11291300899341816	[517]	[642,507,593,592]	2	hSpCas9	negative selection	5548709
1002065	1002088	4	+	27260156	BXPC3	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.15273684450786434	[576]	[493,670,788,755]	3	hSpCas9	negative selection	5548710
989309	989332	4	-	27260156	BXPC3	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.2892092516090834	[43]	[166,93,104,72]	9	hSpCas9	negative selection	5570870
991515	991538	4	+	27260156	BXPC3	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.05300505435897318	[651]	[607,611,794,613]	-1	hSpCas9	negative selection	5570871
990146	990169	4	-	27260156	BXPC3	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.006967967321401036	[694]	[624,834,652,784]	0	hSpCas9	negative selection	5570872
1003081	1003104	4	-	27260156	BXPC3	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.15679587372915205	[745]	[641,646,727,798]	-4	hSpCas9	negative selection	5612966
1000617	1000640	4	-	27260156	BXPC3	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.07809636408194237	[335]	[271,301,383,386]	-2	hSpCas9	negative selection	5612967
1000651	1000674	4	-	27260156	BXPC3	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.022836308109435766	[650]	[686,564,685,751]	0	hSpCas9	negative selection	5612968
991496	991519	4	-	27260156	BXPC3	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.278400199056279	[102]	[98,63,79,114]	-6	hSpCas9	negative selection	5635124
1002019	1002042	4	+	27260156	A673	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.08852874529171095	[667]	[895,827,917,767]	2	hSpCas9	negative selection	5669959
1003040	1003063	4	+	27260156	A673	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.05272455996967615	[517]	[719,537,559,780]	1	hSpCas9	negative selection	5669960
1002065	1002088	4	+	27260156	A673	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.23857628622921567	[576]	[865,773,798,836]	5	hSpCas9	negative selection	5669961
989309	989332	4	-	27260156	A673	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	0.6586892904421537	[43]	[123,45,86,81]	9	hSpCas9	negative selection	5692121
991515	991538	4	+	27260156	A673	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.12488254184490016	[651]	[744,693,660,777]	-3	hSpCas9	negative selection	5692122
990146	990169	4	-	27260156	A673	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.09113371846203233	[694]	[795,943,606,783]	-2	hSpCas9	negative selection	5692123
1003081	1003104	4	-	27260156	A673	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.16320121166383128	[745]	[765,830,729,870]	-4	hSpCas9	negative selection	5734217
1000617	1000640	4	-	27260156	A673	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.18579528523436922	[335]	[297,383,323,407]	-4	hSpCas9	negative selection	5734218
1000651	1000674	4	-	27260156	A673	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.34237924059517577	[650]	[712,598,564,598]	-7	hSpCas9	negative selection	5734219
991496	991519	4	-	27260156	A673	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.4595972539503692	[102]	[197,159,192,129]	9	hSpCas9	negative selection	5756375
1002019	1002042	4	+	27260156	A375	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.06862379990409073	[667]	[784,828,930,472]	-1	hSpCas9	negative selection	5791210
1003040	1003063	4	+	27260156	A375	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.2974616415311503	[517]	[827,988,638,570]	4	hSpCas9	negative selection	5791211
1002065	1002088	4	+	27260156	A375	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.19162408785652119	[576]	[780,793,751,753]	2	hSpCas9	negative selection	5791212
989309	989332	4	-	27260156	A375	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.3631371025147736	[43]	[97,142,215,78]	9	hSpCas9	negative selection	5813372
991515	991538	4	+	27260156	A375	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.09108375811790165	[651]	[548,842,816,669]	-1	hSpCas9	negative selection	5813373
990146	990169	4	-	27260156	A375	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.13581523872328877	[694]	[784,953,581,669]	-2	hSpCas9	negative selection	5813374
1003081	1003104	4	-	27260156	A375	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.18008249129129944	[745]	[611,823,1079,585]	-3	hSpCas9	negative selection	5855468
1000617	1000640	4	-	27260156	A375	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.4858728963552105	[335]	[252,340,169,354]	-6	hSpCas9	negative selection	5855469
1000651	1000674	4	-	27260156	A375	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.04767811238202313	[650]	[997,649,594,691]	0	hSpCas9	negative selection	5855470
991496	991519	4	-	27260156	A375	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.037458019438475265	[102]	[110,153,95,112]	0	hSpCas9	negative selection	5877626
1002019	1002042	4	+	27260156	COLO741	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.29331608727285896	[667]	[1258,1069,839]	6	hSpCas9	negative selection	5912461
1003040	1003063	4	+	27260156	COLO741	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.38358475213645304	[517]	[1026,879,706]	7	hSpCas9	negative selection	5912462
1002065	1002088	4	+	27260156	COLO741	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.3486206135101598	[576]	[947,984,885]	7	hSpCas9	negative selection	5912463
989309	989332	4	-	27260156	COLO741	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.2127218514011004	[43]	[141,152,98]	9	hSpCas9	negative selection	5934623
991515	991538	4	+	27260156	COLO741	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.1283675087150808	[651]	[828,834,635]	-3	hSpCas9	negative selection	5934624
990146	990169	4	-	27260156	COLO741	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.003425279325901087	[694]	[1084,865,732]	0	hSpCas9	negative selection	5934625
1003081	1003104	4	-	27260156	COLO741	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.022448317786577632	[745]	[1044,990,796]	0	hSpCas9	negative selection	5976719
1000617	1000640	4	-	27260156	COLO741	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	0.11509507972007177	[335]	[508,374,509]	2	hSpCas9	negative selection	5976720
1000651	1000674	4	-	27260156	COLO741	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.5046015016578258	[650]	[689,501,574]	-8	hSpCas9	negative selection	5976721
991496	991519	4	-	27260156	COLO741	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.16875867941358047	[102]	[162,81,195]	3	hSpCas9	negative selection	5998877
1002019	1002042	4	+	27260156	CAL120	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.00567843848235694	[667]	[966,767,788]	0	hSpCas9	negative selection	6033712
1003040	1003063	4	+	27260156	CAL120	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.005335825137301631	[517]	[642,589,705]	0	hSpCas9	negative selection	6033713
1002065	1002088	4	+	27260156	CAL120	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.32460743840934736	[576]	[1259,845,649]	5	hSpCas9	negative selection	6033714
989309	989332	4	-	27260156	CAL120	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.3457419714929069	[43]	[174,62,183]	9	hSpCas9	negative selection	6055874
991515	991538	4	+	27260156	CAL120	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.48524828195143865	[651]	[1891,854,779]	7	hSpCas9	negative selection	6055875
990146	990169	4	-	27260156	CAL120	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	0.04510402633474542	[694]	[890,927,857]	0	hSpCas9	negative selection	6055876
1003081	1003104	4	-	27260156	CAL120	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.15468537038582153	[745]	[1228,783,552]	-2	hSpCas9	negative selection	6097970
1000617	1000640	4	-	27260156	CAL120	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.4769494851748914	[335]	[208,245,429]	-6	hSpCas9	negative selection	6097971
1000651	1000674	4	-	27260156	CAL120	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	0.05862329144985445	[650]	[1024,744,788]	0	hSpCas9	negative selection	6097972
991496	991519	4	-	27260156	CAL120	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.02016088024627649	[102]	[103,102,167]	0	hSpCas9	negative selection	6120128
1002019	1002042	4	+	27260156	CADOES1	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.08495286465931978	[667]	[469,691,557,624]	-1	hSpCas9	negative selection	6154963
1003040	1003063	4	+	27260156	CADOES1	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.33374156462151566	[517]	[777,761,449,431]	5	hSpCas9	negative selection	6154964
1002065	1002088	4	+	27260156	CADOES1	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.2812174178723583	[576]	[815,611,682,490]	5	hSpCas9	negative selection	6154965
989309	989332	4	-	27260156	CADOES1	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.504635973739702	[43]	[81,72,153,156]	9	hSpCas9	negative selection	6177125
991515	991538	4	+	27260156	CADOES1	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.14985705114884823	[651]	[412,635,636,498]	-3	hSpCas9	negative selection	6177126
990146	990169	4	-	27260156	CADOES1	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.21527259490274842	[694]	[537,471,583,635]	-4	hSpCas9	negative selection	6177127
1003081	1003104	4	-	27260156	CADOES1	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.3786728382505103	[745]	[375,681,576,498]	-6	hSpCas9	negative selection	6219221
1000617	1000640	4	-	27260156	CADOES1	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.3968519649301206	[335]	[301,204,259,179]	-6	hSpCas9	negative selection	6219222
1000651	1000674	4	-	27260156	CADOES1	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.41233589305294	[650]	[422,381,526,488]	-6	hSpCas9	negative selection	6219223
991496	991519	4	-	27260156	CADOES1	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.31537996841070615	[102]	[104,91,154,124]	5	hSpCas9	negative selection	6241379
1002019	1002042	4	+	27260156	EWS502	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.2502454240612272	[667]	[439,601,743,612]	-4	hSpCas9	negative selection	6276214
1003040	1003063	4	+	27260156	EWS502	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.2266285359066358	[517]	[689,676,657,524]	4	hSpCas9	negative selection	6276215
1002065	1002088	4	+	27260156	EWS502	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.5068376108338332	[576]	[859,871,984,746]	8	hSpCas9	negative selection	6276216
989309	989332	4	-	27260156	EWS502	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.3153864418066648	[43]	[110,105,110,137]	9	hSpCas9	negative selection	6298376
991515	991538	4	+	27260156	EWS502	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.14107865133827813	[651]	[470,664,689,699]	-3	hSpCas9	negative selection	6298377
990146	990169	4	-	27260156	EWS502	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.14912062990022618	[694]	[582,583,680,829]	-3	hSpCas9	negative selection	6298378
1003081	1003104	4	-	27260156	EWS502	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	0.06093352586369161	[745]	[904,550,852,998]	1	hSpCas9	negative selection	6340472
1000617	1000640	4	-	27260156	EWS502	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.2811860191870597	[335]	[310,291,365,192]	-5	hSpCas9	negative selection	6340473
1000651	1000674	4	-	27260156	EWS502	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.2540388441182131	[650]	[470,585,653,615]	-4	hSpCas9	negative selection	6340474
991496	991519	4	-	27260156	EWS502	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.03265920647048626	[102]	[120,109,145,64]	0	hSpCas9	negative selection	6362630
1002019	1002042	4	+	27260156	EW8	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.21988687749689362	[667]	[663,590,591,682]	4	hSpCas9	negative selection	6397465
1003040	1003063	4	+	27260156	EW8	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.07676851787983952	[517]	[411,380,434,538]	1	hSpCas9	negative selection	6397466
1002065	1002088	4	+	27260156	EW8	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.4340984413954242	[576]	[658,509,657,695]	7	hSpCas9	negative selection	6397467
989309	989332	4	-	27260156	EW8	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.4801197044358114	[43]	[163,58,30,161]	9	hSpCas9	negative selection	6419627
991515	991538	4	+	27260156	EW8	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.02800505911101625	[651]	[758,485,423,527]	0	hSpCas9	negative selection	6419628
990146	990169	4	-	27260156	EW8	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.1358060492960675	[694]	[546,442,454,616]	-3	hSpCas9	negative selection	6419629
1003081	1003104	4	-	27260156	EW8	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	0.15152897416065347	[745]	[702,1045,524,440]	2	hSpCas9	negative selection	6461723
1000617	1000640	4	-	27260156	EW8	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.10926209570628181	[335]	[229,352,211,218]	-2	hSpCas9	negative selection	6461724
1000651	1000674	4	-	27260156	EW8	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.3220302796495988	[650]	[549,418,279,475]	-5	hSpCas9	negative selection	6461725
991496	991519	4	-	27260156	EW8	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.022040254167181583	[102]	[137,94,53,62]	0	hSpCas9	negative selection	6483881
1002019	1002042	4	+	27260156	CORL105	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.15025573363531874	[667]	[860,871,962,789]	3	hSpCas9	negative selection	6518716
1003040	1003063	4	+	27260156	CORL105	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	-0.07284368241688989	[517]	[708,543,578,479]	-1	hSpCas9	negative selection	6518717
1002065	1002088	4	+	27260156	CORL105	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.2573347457090318	[576]	[784,698,931,833]	5	hSpCas9	negative selection	6518718
989309	989332	4	-	27260156	CORL105	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	0.762267766376922	[43]	[76,101,125,49]	9	hSpCas9	negative selection	6540878
991515	991538	4	+	27260156	CORL105	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.14535968127348092	[651]	[770,616,761,625]	-3	hSpCas9	negative selection	6540879
990146	990169	4	-	27260156	CORL105	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.06011822591537663	[694]	[731,708,938,765]	-1	hSpCas9	negative selection	6540880
1003081	1003104	4	-	27260156	CORL105	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.18466360559100847	[745]	[709,717,887,774]	-3	hSpCas9	negative selection	6582974
1000617	1000640	4	-	27260156	CORL105	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.40970378146430403	[335]	[261,294,420,224]	-6	hSpCas9	negative selection	6582975
1000651	1000674	4	-	27260156	CORL105	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.3261753979562291	[650]	[409,616,853,581]	-5	hSpCas9	negative selection	6582976
991496	991519	4	-	27260156	CORL105	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.14435145186473752	[102]	[47,105,189,102]	-3	hSpCas9	negative selection	6605132
1002019	1002042	4	+	27260156	HS294T	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.006111705114655863	[667]	[145,161,263,522]	0	hSpCas9	negative selection	6639967
1003040	1003063	4	+	27260156	HS294T	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.5466252752051421	[517]	[259,218,362,340]	7	hSpCas9	negative selection	6639968
1002065	1002088	4	+	27260156	HS294T	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.16981884911129513	[576]	[138,263,231,403]	2	hSpCas9	negative selection	6639969
989309	989332	4	-	27260156	HS294T	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.5419258479530487	[43]	[43,37,66,49]	9	hSpCas9	negative selection	6662129
991515	991538	4	+	27260156	HS294T	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.29464453307254335	[651]	[265,130,130,306]	-4	hSpCas9	negative selection	6662130
990146	990169	4	-	27260156	HS294T	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	0.6947721807461195	[694]	[236,609,352,574]	8	hSpCas9	negative selection	6662131
1003081	1003104	4	-	27260156	HS294T	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.37432273286941353	[745]	[151,240,262,242]	-5	hSpCas9	negative selection	6704225
1000617	1000640	4	-	27260156	HS294T	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.4921847126737237	[335]	[130,52,73,111]	-6	hSpCas9	negative selection	6704226
1000651	1000674	4	-	27260156	HS294T	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.7640252556759308	[650]	[79,152,201,166]	-8	hSpCas9	negative selection	6704227
991496	991519	4	-	27260156	HS294T	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.6052696124756582	[102]	[30,125,33,49]	7	hSpCas9	negative selection	6726383
1002019	1002042	4	+	27260156	HCC44	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.2509996875125855	[667]	[651,478,840,621]	-4	hSpCas9	negative selection	6761218
1003040	1003063	4	+	27260156	HCC44	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.17575460711418073	[517]	[783,487,832,603]	3	hSpCas9	negative selection	6761219
1002065	1002088	4	+	27260156	HCC44	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.35372473183748854	[576]	[1113,515,1182,652]	6	hSpCas9	negative selection	6761220
989309	989332	4	-	27260156	HCC44	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.4142841017945438	[43]	[130,71,68,250]	9	hSpCas9	negative selection	6783380
991515	991538	4	+	27260156	HCC44	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.10736805829491691	[651]	[796,734,1226,504]	1	hSpCas9	negative selection	6783381
990146	990169	4	-	27260156	HCC44	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	0.5596018810965618	[694]	[845,1173,1587,1062]	8	hSpCas9	negative selection	6783382
1003081	1003104	4	-	27260156	HCC44	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.23517550205606919	[745]	[538,699,1068,603]	-4	hSpCas9	negative selection	6825476
1000617	1000640	4	-	27260156	HCC44	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.08507719721884016	[335]	[308,266,644,269]	-1	hSpCas9	negative selection	6825477
1000651	1000674	4	-	27260156	HCC44	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.41635120723728475	[650]	[500,550,559,585]	-6	hSpCas9	negative selection	6825478
991496	991519	4	-	27260156	HCC44	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.2806633535967067	[102]	[105,124,229,118]	4	hSpCas9	negative selection	6847634
1002019	1002042	4	+	27260156	G402	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.366043993476455	[667]	[685,778,370,703]	-4	hSpCas9	negative selection	6882469
1003040	1003063	4	+	27260156	G402	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.23503736203809905	[517]	[755,874,647,704]	3	hSpCas9	negative selection	6882470
1002065	1002088	4	+	27260156	G402	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	-0.46376620037484817	[576]	[614,541,453,448]	-5	hSpCas9	negative selection	6882471
989309	989332	4	-	27260156	G402	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.573186304842394	[43]	[213,47,180,194]	9	hSpCas9	negative selection	6904631
991515	991538	4	+	27260156	G402	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.153144788972026	[651]	[589,830,888,545]	-2	hSpCas9	negative selection	6904632
990146	990169	4	-	27260156	G402	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.14066814913498615	[694]	[632,870,526,1016]	-2	hSpCas9	negative selection	6904633
1003081	1003104	4	-	27260156	G402	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.5370313175852017	[745]	[736,711,605,479]	-6	hSpCas9	negative selection	6946727
1000617	1000640	4	-	27260156	G402	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.05072992256026093	[335]	[356,530,384,314]	0	hSpCas9	negative selection	6946728
1000651	1000674	4	-	27260156	G402	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.35043609724872493	[650]	[1076,619,443,423]	-4	hSpCas9	negative selection	6946729
991496	991519	4	-	27260156	G402	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.10468080363996268	[102]	[66,141,67,247]	1	hSpCas9	negative selection	6968885
1002019	1002042	4	+	27260156	L33	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.3275206458739387	[667]	[986,335,489,762]	7	hSpCas9	negative selection	7003720
1003040	1003063	4	+	27260156	L33	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.03790372038733475	[517]	[425,241,300,632]	0	hSpCas9	negative selection	7003721
1002065	1002088	4	+	27260156	L33	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.45970165316377865	[576]	[739,353,434,877]	8	hSpCas9	negative selection	7003722
989309	989332	4	-	27260156	L33	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.1283655037691198	[43]	[119,34,72,62]	9	hSpCas9	negative selection	7025882
991515	991538	4	+	27260156	L33	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.07163317170975636	[651]	[688,294,485,559]	1	hSpCas9	negative selection	7025883
990146	990169	4	-	27260156	L33	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	0.25107982433947074	[694]	[808,355,510,817]	5	hSpCas9	negative selection	7025884
1003081	1003104	4	-	27260156	L33	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.16626161706364406	[745]	[707,286,407,600]	-4	hSpCas9	negative selection	7067978
1000617	1000640	4	-	27260156	L33	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.20712398702035878	[335]	[358,101,185,258]	-5	hSpCas9	negative selection	7067979
1000651	1000674	4	-	27260156	L33	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.5227685699827779	[650]	[471,183,373,297]	-8	hSpCas9	negative selection	7067980
991496	991519	4	-	27260156	L33	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.21961578391238623	[102]	[103,31,52,86]	-5	hSpCas9	negative selection	7090136
1002019	1002042	4	+	27260156	K562	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.13203172587105427	[667]	[658,641,512,767]	1	hSpCas9	negative selection	7124971
1003040	1003063	4	+	27260156	K562	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.13375730777676959	[517]	[439,453,473,624]	1	hSpCas9	negative selection	7124972
1002065	1002088	4	+	27260156	K562	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.41552214123915987	[576]	[695,679,615,731]	5	hSpCas9	negative selection	7124973
989309	989332	4	-	27260156	K562	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.5072368325733654	[43]	[62,67,229,79]	9	hSpCas9	negative selection	7147133
991515	991538	4	+	27260156	K562	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.2694736764313129	[651]	[406,513,768,250]	-3	hSpCas9	negative selection	7147134
990146	990169	4	-	27260156	K562	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	0.08556381128289858	[694]	[557,319,853,835]	1	hSpCas9	negative selection	7147135
1003081	1003104	4	-	27260156	K562	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.10102023219988876	[745]	[607,610,616,627]	-1	hSpCas9	negative selection	7189229
1000617	1000640	4	-	27260156	K562	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.8484323161606016	[335]	[149,108,237,160]	-7	hSpCas9	negative selection	7189230
1000651	1000674	4	-	27260156	K562	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.2446053635135227	[650]	[371,323,686,540]	-3	hSpCas9	negative selection	7189231
991496	991519	4	-	27260156	K562	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.3572672644078163	[102]	[286,103,75,24]	4	hSpCas9	negative selection	7211387
1002019	1002042	4	+	27260156	HT29	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.09217089646946786	[667]	[853,1126,795,718]	1	hSpCas9	negative selection	7246222
1003040	1003063	4	+	27260156	HT29	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.014131527370913194	[517]	[627,642,614,650]	0	hSpCas9	negative selection	7246223
1002065	1002088	4	+	27260156	HT29	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.31994418158820026	[576]	[966,926,851,773]	6	hSpCas9	negative selection	7246224
989309	989332	4	-	27260156	HT29	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.1481876138422766	[43]	[134,168,110,69]	9	hSpCas9	negative selection	7268384
991515	991538	4	+	27260156	HT29	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.2292268141180233	[651]	[715,776,583,638]	-4	hSpCas9	negative selection	7268385
990146	990169	4	-	27260156	HT29	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	0.14611411527712082	[694]	[981,1142,781,856]	3	hSpCas9	negative selection	7268386
1003081	1003104	4	-	27260156	HT29	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.18812091293634825	[745]	[917,790,842,652]	-4	hSpCas9	negative selection	7310480
1000617	1000640	4	-	27260156	HT29	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.1951224546248997	[335]	[488,290,327,324]	-4	hSpCas9	negative selection	7310481
1000651	1000674	4	-	27260156	HT29	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.1622077666507623	[650]	[759,673,648,737]	-3	hSpCas9	negative selection	7310482
991496	991519	4	-	27260156	HT29	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.34484650587777455	[102]	[200,200,127,116]	6	hSpCas9	negative selection	7332638
1002019	1002042	4	+	27260156	MHHES1	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.1740162742712047	[667]	[983,966,844,653]	3	hSpCas9	negative selection	7367473
1003040	1003063	4	+	27260156	MHHES1	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	-0.09441346846505694	[517]	[571,478,670,466]	-2	hSpCas9	negative selection	7367474
1002065	1002088	4	+	27260156	MHHES1	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.5181830093163314	[576]	[1208,1043,935,628]	8	hSpCas9	negative selection	7367475
989309	989332	4	-	27260156	MHHES1	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.1182528359094293	[43]	[63,81,154,116]	9	hSpCas9	negative selection	7389635
991515	991538	4	+	27260156	MHHES1	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.32076891632189386	[651]	[454,652,729,509]	-6	hSpCas9	negative selection	7389636
990146	990169	4	-	27260156	MHHES1	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.2398386003635915	[694]	[858,581,512,689]	-4	hSpCas9	negative selection	7389637
1003081	1003104	4	-	27260156	MHHES1	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.042946869681437905	[745]	[800,725,855,842]	-1	hSpCas9	negative selection	7431731
1000617	1000640	4	-	27260156	MHHES1	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.06266517126401344	[335]	[347,461,368,287]	-1	hSpCas9	negative selection	7431732
1000651	1000674	4	-	27260156	MHHES1	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.1807370192899697	[650]	[715,891,532,498]	-3	hSpCas9	negative selection	7431733
991496	991519	4	-	27260156	MHHES1	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.021135537240375868	[102]	[55,185,200,31]	0	hSpCas9	negative selection	7453889
1002019	1002042	4	+	27260156	MEWO	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.30508487586407373	[667]	[989,652,715]	6	hSpCas9	negative selection	7488724
1003040	1003063	4	+	27260156	MEWO	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.1275528546076709	[517]	[388,720,449]	3	hSpCas9	negative selection	7488725
1002065	1002088	4	+	27260156	MEWO	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.20437985714428508	[576]	[801,552,545]	4	hSpCas9	negative selection	7488726
989309	989332	4	-	27260156	MEWO	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.40019343328672	[43]	[107,66,150]	9	hSpCas9	negative selection	7510886
991515	991538	4	+	27260156	MEWO	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.29461655977065376	[651]	[619,415,479]	-6	hSpCas9	negative selection	7510887
990146	990169	4	-	27260156	MEWO	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.116037978374666	[694]	[764,545,520]	-3	hSpCas9	negative selection	7510888
1003081	1003104	4	-	27260156	MEWO	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.05281839743478278	[745]	[886,643,528]	-1	hSpCas9	negative selection	7552982
1000617	1000640	4	-	27260156	MEWO	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	0.1341875592109834	[335]	[518,263,285]	3	hSpCas9	negative selection	7552983
1000651	1000674	4	-	27260156	MEWO	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.12876101584735944	[650]	[606,494,578]	-3	hSpCas9	negative selection	7552984
991496	991519	4	-	27260156	MEWO	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.173292976909309	[102]	[98,79,79]	-4	hSpCas9	negative selection	7575140
1002019	1002042	4	+	27260156	LNCAPCLONEFGC	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.19025811366259754	[667]	[394,532,708,512]	-3	hSpCas9	negative selection	7609975
1003040	1003063	4	+	27260156	LNCAPCLONEFGC	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.006684471122469587	[517]	[487,368,573,475]	0	hSpCas9	negative selection	7609976
1002065	1002088	4	+	27260156	LNCAPCLONEFGC	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.07044698415919981	[576]	[562,503,503,619]	1	hSpCas9	negative selection	7609977
989309	989332	4	-	27260156	LNCAPCLONEFGC	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.5239377210049567	[43]	[46,206,123,76]	9	hSpCas9	negative selection	7632137
991515	991538	4	+	27260156	LNCAPCLONEFGC	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.0710596642586871	[651]	[595,368,705,610]	-1	hSpCas9	negative selection	7632138
990146	990169	4	-	27260156	LNCAPCLONEFGC	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	0.03558753326600883	[694]	[717,564,694,613]	0	hSpCas9	negative selection	7632139
1003081	1003104	4	-	27260156	LNCAPCLONEFGC	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.43739500885535465	[745]	[503,339,564,606]	-6	hSpCas9	negative selection	7674233
1000617	1000640	4	-	27260156	LNCAPCLONEFGC	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.5640178332083032	[335]	[267,151,173,226]	-7	hSpCas9	negative selection	7674234
1000651	1000674	4	-	27260156	LNCAPCLONEFGC	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.6105979786883053	[650]	[321,313,354,554]	-7	hSpCas9	negative selection	7674235
991496	991519	4	-	27260156	LNCAPCLONEFGC	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.824783270881557	[102]	[102,168,239,160]	9	hSpCas9	negative selection	7696391
1002019	1002042	4	+	27260156	PANC0327	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.053089774529542666	[667]	[1007,511,590,396]	0	hSpCas9	negative selection	7731226
1003040	1003063	4	+	27260156	PANC0327	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.3299664167627995	[517]	[373,740,728,431]	5	hSpCas9	negative selection	7731227
1002065	1002088	4	+	27260156	PANC0327	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.6317023635612568	[576]	[895,678,988,635]	8	hSpCas9	negative selection	7731228
989309	989332	4	-	27260156	PANC0327	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.33659904727793	[43]	[71,134,116,63]	9	hSpCas9	negative selection	7753388
991515	991538	4	+	27260156	PANC0327	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.1110869227405481	[651]	[591,538,503,874]	1	hSpCas9	negative selection	7753389
990146	990169	4	-	27260156	PANC0327	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.0859458960584899	[694]	[577,374,698,700]	-1	hSpCas9	negative selection	7753390
1003081	1003104	4	-	27260156	PANC0327	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.4828122163074141	[745]	[479,376,638,413]	-6	hSpCas9	negative selection	7795484
1000617	1000640	4	-	27260156	PANC0327	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.41579080715973055	[335]	[275,217,251,153]	-6	hSpCas9	negative selection	7795485
1000651	1000674	4	-	27260156	PANC0327	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.154195564276429	[650]	[743,465,544,348]	-2	hSpCas9	negative selection	7795486
991496	991519	4	-	27260156	PANC0327	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.5508326921854989	[102]	[47,82,70,43]	-7	hSpCas9	negative selection	7817642
1002019	1002042	4	+	27260156	NCIH2009	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.17610438881631763	[667]	[1152,1224,799]	2	hSpCas9	negative selection	7852477
1003040	1003063	4	+	27260156	NCIH2009	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.35636356927792784	[517]	[1102,862,847]	5	hSpCas9	negative selection	7852478
1002065	1002088	4	+	27260156	NCIH2009	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.10076141525366594	[576]	[972,776,864]	1	hSpCas9	negative selection	7852479
989309	989332	4	-	27260156	NCIH2009	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	0.9567750152109182	[43]	[138,99,122]	9	hSpCas9	negative selection	7874639
991515	991538	4	+	27260156	NCIH2009	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.42454746303562885	[651]	[621,887,509]	-5	hSpCas9	negative selection	7874640
990146	990169	4	-	27260156	NCIH2009	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.021637732808775567	[694]	[1117,900,881]	0	hSpCas9	negative selection	7874641
1003081	1003104	4	-	27260156	NCIH2009	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.3139737826158559	[745]	[968,820,749]	-4	hSpCas9	negative selection	7916735
1000617	1000640	4	-	27260156	NCIH2009	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.16248993695805064	[335]	[550,342,390]	-2	hSpCas9	negative selection	7916736
1000651	1000674	4	-	27260156	NCIH2009	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.25606947981038786	[650]	[868,750,684]	-3	hSpCas9	negative selection	7916737
991496	991519	4	-	27260156	NCIH2009	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.01884219429771994	[102]	[109,116,192]	0	hSpCas9	negative selection	7938893
1002019	1002042	4	+	27260156	NCIH1373	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.14706493559275746	[667]	[834,566,963,257]	1	hSpCas9	negative selection	7973728
1003040	1003063	4	+	27260156	NCIH1373	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.6757190950234251	[517]	[1418,803,533,276]	6	hSpCas9	negative selection	7973729
1002065	1002088	4	+	27260156	NCIH1373	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.9115441448274183	[576]	[1541,1246,1186,239]	8	hSpCas9	negative selection	7973730
989309	989332	4	-	27260156	NCIH1373	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.514576014226133	[43]	[118,56,217,45]	9	hSpCas9	negative selection	7995890
991515	991538	4	+	27260156	NCIH1373	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.6949799698648655	[651]	[471,342,600,103]	-6	hSpCas9	negative selection	7995891
990146	990169	4	-	27260156	NCIH1373	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	0.12950074305922932	[694]	[1035,934,454,266]	1	hSpCas9	negative selection	7995892
1003081	1003104	4	-	27260156	NCIH1373	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.19301887214630536	[745]	[685,763,817,166]	-2	hSpCas9	negative selection	8037986
1000617	1000640	4	-	27260156	NCIH1373	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.7226727229271706	[335]	[215,218,218,67]	-6	hSpCas9	negative selection	8037987
1000651	1000674	4	-	27260156	NCIH1373	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.1383023333141679	[650]	[815,433,687,200]	-1	hSpCas9	negative selection	8037988
991496	991519	4	-	27260156	NCIH1373	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.13841127045686674	[102]	[39,141,158,39]	1	hSpCas9	negative selection	8060144
1002019	1002042	4	+	27260156	PATU8902	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.6663984058881165	[667]	[803,565,604,325]	-6	hSpCas9	negative selection	8094979
1003040	1003063	4	+	27260156	PATU8902	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.6358264553504196	[517]	[688,1037,1131,1685]	6	hSpCas9	negative selection	8094980
1002065	1002088	4	+	27260156	PATU8902	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.11796568215547093	[576]	[841,861,811,995]	1	hSpCas9	negative selection	8094981
989309	989332	4	-	27260156	PATU8902	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.6173569053544214	[43]	[157,97,154,369]	9	hSpCas9	negative selection	8117141
991515	991538	4	+	27260156	PATU8902	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.1237513378536016	[651]	[952,731,979,1326]	1	hSpCas9	negative selection	8117142
990146	990169	4	-	27260156	PATU8902	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	0.24008535219114624	[694]	[849,1756,897,1125]	2	hSpCas9	negative selection	8117143
1003081	1003104	4	-	27260156	PATU8902	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.09514161970086421	[745]	[1381,1115,503,1000]	-1	hSpCas9	negative selection	8159237
1000617	1000640	4	-	27260156	PATU8902	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.43097783016756813	[335]	[197,217,515,419]	-4	hSpCas9	negative selection	8159238
1000651	1000674	4	-	27260156	PATU8902	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.24027722663497333	[650]	[644,820,921,619]	-2	hSpCas9	negative selection	8159239
991496	991519	4	-	27260156	PATU8902	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.3415915404339944	[102]	[129,307,73,250]	3	hSpCas9	negative selection	8181395
1002019	1002042	4	+	27260156	PANC1	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.19710995347025073	[667]	[823,729,568,528]	3	hSpCas9	negative selection	8216230
1003040	1003063	4	+	27260156	PANC1	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.1718002209651085	[517]	[339,588,610,481]	2	hSpCas9	negative selection	8216231
1002065	1002088	4	+	27260156	PANC1	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.26924090289452207	[576]	[690,632,460,597]	4	hSpCas9	negative selection	8216232
989309	989332	4	-	27260156	PANC1	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	0.9170383247692007	[43]	[86,44,51,90]	9	hSpCas9	negative selection	8238392
991515	991538	4	+	27260156	PANC1	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.22326766537913212	[651]	[507,712,458,306]	-4	hSpCas9	negative selection	8238393
990146	990169	4	-	27260156	PANC1	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.4486520588467906	[694]	[365,465,473,442]	-6	hSpCas9	negative selection	8238394
1003081	1003104	4	-	27260156	PANC1	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.02196750478319487	[745]	[758,842,498,477]	0	hSpCas9	negative selection	8280488
1000617	1000640	4	-	27260156	PANC1	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.06037343197444661	[335]	[309,260,268,260]	-1	hSpCas9	negative selection	8280489
1000651	1000674	4	-	27260156	PANC1	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.1892101339169866	[650]	[458,735,567,277]	-3	hSpCas9	negative selection	8280490
991496	991519	4	-	27260156	PANC1	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.135935672335318	[102]	[40,168,58,71]	-2	hSpCas9	negative selection	8302646
1002019	1002042	4	+	27260156	PANC0813	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.37271891085794684	[667]	[1117,879,1007,1062]	6	hSpCas9	negative selection	8337481
1003040	1003063	4	+	27260156	PANC0813	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.3453669646371117	[517]	[672,799,665,932]	5	hSpCas9	negative selection	8337482
1002065	1002088	4	+	27260156	PANC0813	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.5226856960937578	[576]	[938,785,1412,765]	8	hSpCas9	negative selection	8337483
989309	989332	4	-	27260156	PANC0813	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.3410198825103703	[43]	[106,87,98,221]	9	hSpCas9	negative selection	8359643
991515	991538	4	+	27260156	PANC0813	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.07518322752665896	[651]	[789,927,735,771]	1	hSpCas9	negative selection	8359644
990146	990169	4	-	27260156	PANC0813	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	0.08657222386610952	[694]	[1109,895,815,676]	1	hSpCas9	negative selection	8359645
1003081	1003104	4	-	27260156	PANC0813	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.1844887678618869	[745]	[747,834,868,636]	-3	hSpCas9	negative selection	8401739
1000617	1000640	4	-	27260156	PANC0813	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	0.05677696760184431	[335]	[511,357,530,258]	0	hSpCas9	negative selection	8401740
1000651	1000674	4	-	27260156	PANC0813	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.33205578721539086	[650]	[765,547,415,706]	-5	hSpCas9	negative selection	8401741
991496	991519	4	-	27260156	PANC0813	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.21992680295441902	[102]	[173,157,157,79]	3	hSpCas9	negative selection	8423897
1002019	1002042	4	+	27260156	RDES	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.08994971729392726	[667]	[635,658,816,790]	-1	hSpCas9	negative selection	8458732
1003040	1003063	4	+	27260156	RDES	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.35808308043163545	[517]	[623,636,913,929]	6	hSpCas9	negative selection	8458733
1002065	1002088	4	+	27260156	RDES	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.4005369494973673	[576]	[658,767,1157,976]	6	hSpCas9	negative selection	8458734
989309	989332	4	-	27260156	RDES	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.5320244559423377	[43]	[133,116,86,263]	9	hSpCas9	negative selection	8480894
991515	991538	4	+	27260156	RDES	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.03627691973036834	[651]	[592,591,926,861]	0	hSpCas9	negative selection	8480895
990146	990169	4	-	27260156	RDES	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.26617060911519574	[694]	[580,550,723,839]	-4	hSpCas9	negative selection	8480896
1003081	1003104	4	-	27260156	RDES	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.238143612793347	[745]	[653,642,748,889]	-4	hSpCas9	negative selection	8522990
1000617	1000640	4	-	27260156	RDES	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	0.02770229329616669	[335]	[329,286,527,457]	0	hSpCas9	negative selection	8522991
1000651	1000674	4	-	27260156	RDES	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.2234682126079962	[650]	[453,616,768,774]	-4	hSpCas9	negative selection	8522992
991496	991519	4	-	27260156	RDES	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.43661931766111106	[102]	[96,115,155,308]	7	hSpCas9	negative selection	8545148
1002019	1002042	4	+	27260156	PC3	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.1396225427450889	[667]	[501,484,1233,957]	3	hSpCas9	negative selection	8579983
1003040	1003063	4	+	27260156	PC3	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.204547662608494	[517]	[379,630,796,686]	4	hSpCas9	negative selection	8579984
1002065	1002088	4	+	27260156	PC3	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.4919929004974003	[576]	[430,710,1733,824]	8	hSpCas9	negative selection	8579985
989309	989332	4	-	27260156	PC3	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.0444522955084992	[43]	[20,112,166,116]	9	hSpCas9	negative selection	8602145
991515	991538	4	+	27260156	PC3	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.059361226627898334	[651]	[409,513,1278,809]	1	hSpCas9	negative selection	8602146
990146	990169	4	-	27260156	PC3	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.028182641623357485	[694]	[514,423,1165,817]	0	hSpCas9	negative selection	8602147
1003081	1003104	4	-	27260156	PC3	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.19903657641357791	[745]	[465,549,1238,577]	-4	hSpCas9	negative selection	8644241
1000617	1000640	4	-	27260156	PC3	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.18333992556042517	[335]	[212,282,531,245]	-4	hSpCas9	negative selection	8644242
1000651	1000674	4	-	27260156	PC3	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.39831376290347714	[650]	[354,376,813,564]	-7	hSpCas9	negative selection	8644243
991496	991519	4	-	27260156	PC3	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.11296880185412128	[102]	[40,65,222,187]	2	hSpCas9	negative selection	8666399
1002019	1002042	4	+	27260156	PATU8988T	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.10972750164049339	[667]	[676,701,731,672]	2	hSpCas9	negative selection	8701234
1003040	1003063	4	+	27260156	PATU8988T	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	-0.07130659085000979	[517]	[390,583,422,521]	-1	hSpCas9	negative selection	8701235
1002065	1002088	4	+	27260156	PATU8988T	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.24974315995169483	[576]	[571,564,741,770]	4	hSpCas9	negative selection	8701236
989309	989332	4	-	27260156	PATU8988T	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.4342695066650808	[43]	[72,137,139,109]	9	hSpCas9	negative selection	8723396
991515	991538	4	+	27260156	PATU8988T	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.02984619793922405	[651]	[718,616,582,543]	0	hSpCas9	negative selection	8723397
990146	990169	4	-	27260156	PATU8988T	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.22804668731717254	[694]	[471,528,471,838]	-4	hSpCas9	negative selection	8723398
1003081	1003104	4	-	27260156	PATU8988T	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.3170041391987374	[745]	[640,493,459,724]	-5	hSpCas9	negative selection	8765492
1000617	1000640	4	-	27260156	PATU8988T	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.43978927934963735	[335]	[412,142,159,232]	-6	hSpCas9	negative selection	8765493
1000651	1000674	4	-	27260156	PATU8988T	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.24798165593881538	[650]	[510,447,345,832]	-4	hSpCas9	negative selection	8765494
991496	991519	4	-	27260156	PATU8988T	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.13970444459217246	[102]	[127,94,77,138]	2	hSpCas9	negative selection	8787650
1002019	1002042	4	+	27260156	T47D	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.15395641242012803	[667]	[773,552,666,820]	-3	hSpCas9	negative selection	8822485
1003040	1003063	4	+	27260156	T47D	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.02619170899260162	[517]	[578,626,600,650]	0	hSpCas9	negative selection	8822486
1002065	1002088	4	+	27260156	T47D	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.4202224401024316	[576]	[911,795,919,980]	8	hSpCas9	negative selection	8822487
989309	989332	4	-	27260156	T47D	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	0.9941380987248487	[43]	[115,93,60,139]	9	hSpCas9	negative selection	8844647
991515	991538	4	+	27260156	T47D	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.29107838520887314	[651]	[598,581,586,721]	-6	hSpCas9	negative selection	8844648
990146	990169	4	-	27260156	T47D	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.04810986082261259	[694]	[778,772,813,765]	-1	hSpCas9	negative selection	8844649
1003081	1003104	4	-	27260156	T47D	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.2579438966135194	[745]	[768,657,648,841]	-5	hSpCas9	negative selection	8886743
1000617	1000640	4	-	27260156	T47D	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.11812324426337045	[335]	[297,355,398,389]	-3	hSpCas9	negative selection	8886744
1000651	1000674	4	-	27260156	T47D	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.34092815839382234	[650]	[621,568,637,566]	-6	hSpCas9	negative selection	8886745
991496	991519	4	-	27260156	T47D	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.10252165900880872	[102]	[105,151,95,88]	-2	hSpCas9	negative selection	8908901
1002019	1002042	4	+	27260156	SU8686	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.17128015927312434	[667]	[716,680,692,925]	3	hSpCas9	negative selection	8943736
1003040	1003063	4	+	27260156	SU8686	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.386040623693119	[517]	[445,704,708,874]	6	hSpCas9	negative selection	8943737
1002065	1002088	4	+	27260156	SU8686	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.45003047379937133	[576]	[754,753,732,902]	7	hSpCas9	negative selection	8943738
989309	989332	4	-	27260156	SU8686	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.6079779275381905	[43]	[66,118,203,155]	9	hSpCas9	negative selection	8965898
991515	991538	4	+	27260156	SU8686	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.08510346030262794	[651]	[507,605,842,840]	1	hSpCas9	negative selection	8965899
990146	990169	4	-	27260156	SU8686	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	0.060239373246691263	[694]	[685,729,779,667]	1	hSpCas9	negative selection	8965900
1003081	1003104	4	-	27260156	SU8686	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.07039769476393476	[745]	[475,542,730,1188]	-1	hSpCas9	negative selection	9007994
1000617	1000640	4	-	27260156	SU8686	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	0.02754999454520357	[335]	[365,287,254,468]	0	hSpCas9	negative selection	9007995
1000651	1000674	4	-	27260156	SU8686	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.32456190892642117	[650]	[459,390,476,796]	-5	hSpCas9	negative selection	9007996
991496	991519	4	-	27260156	SU8686	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	0.5159538554344996	[102]	[200,82,149,151]	8	hSpCas9	negative selection	9030152
1002019	1002042	4	+	27260156	SKES1	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.002433951431271786	[667]	[537,806,546,759]	0	hSpCas9	negative selection	9064987
1003040	1003063	4	+	27260156	SKES1	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.12653667853911454	[517]	[621,896,395,404]	2	hSpCas9	negative selection	9064988
1002065	1002088	4	+	27260156	SKES1	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.38013754594340443	[576]	[790,894,536,786]	7	hSpCas9	negative selection	9064989
989309	989332	4	-	27260156	SKES1	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.0559699931807534	[43]	[60,129,106,68]	9	hSpCas9	negative selection	9087149
991515	991538	4	+	27260156	SKES1	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.0393919610938529	[651]	[679,824,619,573]	0	hSpCas9	negative selection	9087150
990146	990169	4	-	27260156	SKES1	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	0.042180067325333526	[694]	[686,687,694,764]	0	hSpCas9	negative selection	9087151
1003081	1003104	4	-	27260156	SKES1	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.14870968082084046	[745]	[778,863,512,573]	-3	hSpCas9	negative selection	9129245
1000617	1000640	4	-	27260156	SKES1	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.06327795202661773	[335]	[310,334,217,406]	-1	hSpCas9	negative selection	9129246
1000651	1000674	4	-	27260156	SKES1	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.37942830610470846	[650]	[613,626,433,364]	-7	hSpCas9	negative selection	9129247
991496	991519	4	-	27260156	SKES1	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.04704751333437862	[102]	[50,153,105,86]	-1	hSpCas9	negative selection	9151403
1002019	1002042	4	+	27260156	TOV112D	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	0.1309046196754845	[667]	[831,703,826,571]	2	hSpCas9	negative selection	9186238
1003040	1003063	4	+	27260156	TOV112D	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.2766581006472007	[517]	[553,999,487,557]	5	hSpCas9	negative selection	9186239
1002065	1002088	4	+	27260156	TOV112D	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.5201140891479947	[576]	[614,1217,751,806]	8	hSpCas9	negative selection	9186240
989309	989332	4	-	27260156	TOV112D	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.3227903440080877	[43]	[108,231,32,96]	9	hSpCas9	negative selection	9208400
991515	991538	4	+	27260156	TOV112D	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	0.19174180558770315	[651]	[549,905,983,569]	3	hSpCas9	negative selection	9208401
990146	990169	4	-	27260156	TOV112D	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	0.14894771673185336	[694]	[734,774,781,790]	3	hSpCas9	negative selection	9208402
1003081	1003104	4	-	27260156	TOV112D	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	0.03158934238068023	[745]	[489,982,867,743]	0	hSpCas9	negative selection	9250496
1000617	1000640	4	-	27260156	TOV112D	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.10038205386632998	[335]	[548,322,267,141]	-2	hSpCas9	negative selection	9250497
1000651	1000674	4	-	27260156	TOV112D	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.44874298693602127	[650]	[532,692,455,290]	-7	hSpCas9	negative selection	9250498
991496	991519	4	-	27260156	TOV112D	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.479295875348686	[102]	[73,54,80,80]	-7	hSpCas9	negative selection	9272654
1002019	1002042	4	+	27260156	TC71	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.1058199147515782	[667]	[558,651,714,740]	-3	hSpCas9	negative selection	9307489
1003040	1003063	4	+	27260156	TC71	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	-0.19543442534915084	[517]	[534,374,567,455]	-5	hSpCas9	negative selection	9307490
1002065	1002088	4	+	27260156	TC71	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.2548202863112039	[576]	[923,670,704,642]	6	hSpCas9	negative selection	9307491
989309	989332	4	-	27260156	TC71	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.3714716257478679	[43]	[106,162,89,129]	9	hSpCas9	negative selection	9329651
991515	991538	4	+	27260156	TC71	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.07541000633044953	[651]	[709,678,513,759]	-2	hSpCas9	negative selection	9329652
990146	990169	4	-	27260156	TC71	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.159700250013542	[694]	[693,700,497,786]	-4	hSpCas9	negative selection	9329653
1003081	1003104	4	-	27260156	TC71	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.07066610704855691	[745]	[635,799,804,808]	-2	hSpCas9	negative selection	9371747
1000617	1000640	4	-	27260156	TC71	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	0.1071540047477218	[335]	[474,353,329,392]	2	hSpCas9	negative selection	9371748
1000651	1000674	4	-	27260156	TC71	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.10492054362511294	[650]	[779,560,653,593]	-3	hSpCas9	negative selection	9371749
991496	991519	4	-	27260156	TC71	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.48498567589253305	[102]	[119,76,48,68]	-8	hSpCas9	negative selection	9393905
1002019	1002042	4	+	27260156	TC32	viability	AGGTCGTCGCGCAGCAGATCCGG	IDUA	ENSG00000127415	-0.32711787106694634	[667]	[539,288,693,561]	-6	hSpCas9	negative selection	9428740
1003040	1003063	4	+	27260156	TC32	viability	GGTCTACGTCACGCGCTACCTGG	IDUA	ENSG00000127415	0.09083283282264748	[517]	[416,372,662,693]	1	hSpCas9	negative selection	9428741
1002065	1002088	4	+	27260156	TC32	viability	CACCCCCATTTACAACGACGAGG	IDUA	ENSG00000127415	0.12034126925773525	[576]	[719,365,682,639]	2	hSpCas9	negative selection	9428742
989309	989332	4	-	27260156	TC32	viability	CGTGCGGGTGTTCCGCTTTGGGG	IDUA	ENSG00000127415	1.774958295359116	[43]	[124,175,136,103]	9	hSpCas9	negative selection	9450902
991515	991538	4	+	27260156	TC32	viability	GTACTGACGCAGCCAGCGCGTGG	IDUA	ENSG00000127415	-0.23514179389518164	[651]	[545,287,637,695]	-4	hSpCas9	negative selection	9450903
990146	990169	4	-	27260156	TC32	viability	GCAGGCCAACGTGTGCGACGTGG	IDUA	ENSG00000127415	-0.0658457226851511	[694]	[603,382,901,718]	-1	hSpCas9	negative selection	9450904
1003081	1003104	4	-	27260156	TC32	viability	CAGGCGCCGCCACTCGCCGTCGG	IDUA	ENSG00000127415	-0.4364961687244656	[745]	[467,379,613,662]	-7	hSpCas9	negative selection	9492998
1000617	1000640	4	-	27260156	TC32	viability	GTAGCTCAGGCCCCGTCCAGTGG	IDUA	ENSG00000127415	-0.053539617956560426	[335]	[389,170,372,316]	-1	hSpCas9	negative selection	9492999
1000651	1000674	4	-	27260156	TC32	viability	GAAGGTCCAGGTACCCGTCCAGG	IDUA	ENSG00000127415	-0.11650465254884229	[650]	[577,425,742,556]	-2	hSpCas9	negative selection	9493000
991496	991519	4	-	27260156	TC32	viability	GTACCGCCCGCGGGAGTACCTGG	IDUA	ENSG00000127415	-0.047027383995676075	[102]	[130,17,99,148]	-1	hSpCas9	negative selection	9515156
987209	987232	4	-	27869803	HPAFII	viability after 27 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	1.4754610411582774	[122]	[37,297,NaN]	9	hSpCas9	negative selection	9589380
987827	987850	4	-	27869803	HPAFII	viability after 27 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.2484301674705699	[291]	[321,65,NaN]	2	hSpCas9	negative selection	9589381
1000593	1000616	4	+	27869803	HPAFII	viability after 27 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-2.0793389595640877	[18]	[3,0,NaN]	-8	hSpCas9	negative selection	9589403
1000910	1000933	4	-	27869803	HPAFII	viability after 27 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.4401887543975196	[520]	[339,397,NaN]	3	hSpCas9	negative selection	9589404
1001492	1001515	4	+	27869803	HPAFII	viability after 27 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	-0.04661494705453273	[810]	[570,280,NaN]	0	hSpCas9	negative selection	9589405
1002430	1002453	4	+	27869803	HPAFII	viability after 27 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	1.0937928419759875	[168]	[223,160,NaN]	8	hSpCas9	negative selection	9589407
987209	987232	4	-	27869803	HPAFII	viability after 15 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	0.7519858743649084	[122]	[139,273,NaN]	8	hSpCas9	negative selection	9671829
987827	987850	4	-	27869803	HPAFII	viability after 15 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.6913541654657199	[291]	[938,237,NaN]	7	hSpCas9	negative selection	9671830
1000593	1000616	4	+	27869803	HPAFII	viability after 15 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-1.5171348446981625	[18]	[16,0,NaN]	-8	hSpCas9	negative selection	9671852
1000910	1000933	4	-	27869803	HPAFII	viability after 15 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	-0.0031391265720868144	[520]	[739,445,NaN]	0	hSpCas9	negative selection	9671853
1001492	1001515	4	+	27869803	HPAFII	viability after 15 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.1514861993467176	[810]	[1186,831,NaN]	1	hSpCas9	negative selection	9671854
1002430	1002453	4	+	27869803	HPAFII	viability after 15 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	0.7546317168125481	[168]	[430,228,NaN]	8	hSpCas9	negative selection	9671856
987209	987232	4	-	27869803	ASPC1	viability after 36 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	-0.1559739749374256	[276]	[52,118,83]	-2	hSpCas9	negative selection	9754278
987827	987850	4	-	27869803	ASPC1	viability after 36 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	-0.21250657567853876	[887]	[252,313,237]	-2	hSpCas9	negative selection	9754279
1000593	1000616	4	+	27869803	ASPC1	viability after 36 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	2.0893488127228093	[49]	[255,4,0]	9	hSpCas9	negative selection	9754301
1000910	1000933	4	-	27869803	ASPC1	viability after 36 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.004094502543787959	[1339]	[344,748,328]	0	hSpCas9	negative selection	9754302
1001492	1001515	4	+	27869803	ASPC1	viability after 36 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.022876432048903883	[1849]	[703,574,679]	0	hSpCas9	negative selection	9754303
1002430	1002453	4	+	27869803	ASPC1	viability after 36 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	-0.5060804759766866	[406]	[78,168,58]	-5	hSpCas9	negative selection	9754305
987209	987232	4	-	27869803	PATU8988S	viability after 35 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	-0.21963095828018897	[161]	[69,41,NaN]	-2	hSpCas9	negative selection	9836727
987827	987850	4	-	27869803	PATU8988S	viability after 35 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.8107784681218302	[587]	[377,452,NaN]	8	hSpCas9	negative selection	9836728
1000593	1000616	4	+	27869803	PATU8988S	viability after 35 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-0.5956696338781398	[46]	[23,0,NaN]	-6	hSpCas9	negative selection	9836750
1000910	1000933	4	-	27869803	PATU8988S	viability after 35 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	-0.07744047981801827	[1149]	[419,457,NaN]	-1	hSpCas9	negative selection	9836751
1001492	1001515	4	+	27869803	PATU8988S	viability after 35 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.6169777158587748	[1405]	[850,885,NaN]	6	hSpCas9	negative selection	9836752
1002430	1002453	4	+	27869803	PATU8988S	viability after 35 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	0.14283557531612845	[340]	[208,93,NaN]	1	hSpCas9	negative selection	9836754
987209	987232	4	-	27869803	PATU8988S	viability after 31 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	-0.2215923608078636	[161]	[50,60,NaN]	-3	hSpCas9	negative selection	9919176
987827	987850	4	-	27869803	PATU8988S	viability after 31 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.9861782031493673	[587]	[324,641,NaN]	9	hSpCas9	negative selection	9919177
1000593	1000616	4	+	27869803	PATU8988S	viability after 31 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-0.4540966387586458	[46]	[14,11,NaN]	-5	hSpCas9	negative selection	9919199
1000910	1000933	4	-	27869803	PATU8988S	viability after 31 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	-0.029112111048519296	[1149]	[422,482,NaN]	0	hSpCas9	negative selection	9919200
1001492	1001515	4	+	27869803	PATU8988S	viability after 31 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	0.6815765337763324	[1405]	[874,929,NaN]	7	hSpCas9	negative selection	9919201
1002430	1002453	4	+	27869803	PATU8988S	viability after 31 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	0.18786574228411196	[340]	[164,141,NaN]	2	hSpCas9	negative selection	9919203
987209	987232	4	-	27869803	HPAFII	viability after 35 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	1.1413058303487196	[122]	[15,273,NaN]	7	hSpCas9	negative selection	10001625
987827	987850	4	-	27869803	HPAFII	viability after 35 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	-0.05682479132000087	[291]	[135,148,NaN]	0	hSpCas9	negative selection	10001626
1000593	1000616	4	+	27869803	HPAFII	viability after 35 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-1.203072873758538	[18]	[6,0,NaN]	-6	hSpCas9	negative selection	10001648
1000910	1000933	4	-	27869803	HPAFII	viability after 35 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.49223973747795813	[520]	[378,361,NaN]	3	hSpCas9	negative selection	10001649
1001492	1001515	4	+	27869803	HPAFII	viability after 35 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	-0.11047392304298143	[810]	[392,365,NaN]	0	hSpCas9	negative selection	10001650
1002430	1002453	4	+	27869803	HPAFII	viability after 35 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	1.1173603300175952	[168]	[115,263,NaN]	7	hSpCas9	negative selection	10001652
987209	987232	4	-	27869803	HPAFII	viability after 31 days	GCTCCTCCAGAAGCGCCGCAGGG	IDUA	ENSG00000127415	1.3949662877268583	[122]	[25,350,NaN]	8	hSpCas9	negative selection	10084074
987827	987850	4	-	27869803	HPAFII	viability after 31 days	TGAGGACGTACTGGTCAGCCTGG	IDUA	ENSG00000127415	0.9726702370868071	[291]	[334,306,NaN]	7	hSpCas9	negative selection	10084075
1000593	1000616	4	+	27869803	HPAFII	viability after 31 days	GCTGACCGTCCTTCTGCAGGGGG	IDUA	ENSG00000127415	-0.5551546439411288	[18]	[12,0,NaN]	-4	hSpCas9	negative selection	10084097
1000910	1000933	4	-	27869803	HPAFII	viability after 31 days	TGTCCTCAAAGTCAGTGAAGTGG	IDUA	ENSG00000127415	0.36224483100694105	[520]	[405,342,NaN]	2	hSpCas9	negative selection	10084098
1001492	1001515	4	+	27869803	HPAFII	viability after 31 days	CCAAGTGGAACTTCGAGACGTGG	IDUA	ENSG00000127415	-0.08360060640108946	[810]	[496,355,NaN]	0	hSpCas9	negative selection	10084099
1002430	1002453	4	+	27869803	HPAFII	viability after 31 days	CGTGCAGCTGTTGCGCAAGCCGG	IDUA	ENSG00000127415	0.7453099061236369	[168]	[169,146,NaN]	5	hSpCas9	negative selection	10084101
987869	987892	4	-	28162770	P31FUJ	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	-0.15744852241100982	[372]	[392]	-1	hSpCas9	negative selection	10172622
1002775	1002798	4	+	28162770	P31FUJ	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	-0.7641267415334616	[197]	[136]	-5	hSpCas9	negative selection	10172623
1002897	1002920	4	+	28162770	P31FUJ	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	0.2199124980083379	[273]	[374]	2	hSpCas9	negative selection	10172624
1000903	1000926	4	-	28162770	P31FUJ	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.03467810645060726	[161]	[194]	0	hSpCas9	negative selection	10172625
1001749	1001772	4	-	28162770	P31FUJ	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	0.2707719694661225	[236]	[335]	3	hSpCas9	negative selection	10172626
1001771	1001794	4	-	28162770	P31FUJ	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	0.9449849148009041	[60]	[137]	9	hSpCas9	negative selection	10172627
1001781	1001804	4	-	28162770	P31FUJ	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	0.04182017569462726	[61]	[74]	0	hSpCas9	negative selection	10172628
1002103	1002126	4	+	28162770	P31FUJ	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	0.17419797579904683	[134]	[178]	1	hSpCas9	negative selection	10172629
1002315	1002338	4	-	28162770	P31FUJ	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	0.6302168927582243	[413]	[752]	7	hSpCas9	negative selection	10172630
1002372	1002395	4	-	28162770	P31FUJ	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	0.7478972396266852	[300]	[593]	8	hSpCas9	negative selection	10172631
987869	987892	4	-	28162770	TF1	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	NaN	[NaN]	[443]	1	hSpCas9	negative selection	10341988
1002775	1002798	4	+	28162770	TF1	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	NaN	[NaN]	[117]	1	hSpCas9	negative selection	10341989
1002897	1002920	4	+	28162770	TF1	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	NaN	[NaN]	[266]	1	hSpCas9	negative selection	10341990
1000903	1000926	4	-	28162770	TF1	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	NaN	[NaN]	[151]	1	hSpCas9	negative selection	10341991
1001749	1001772	4	-	28162770	TF1	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	NaN	[NaN]	[131]	1	hSpCas9	negative selection	10341992
1001771	1001794	4	-	28162770	TF1	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10341993
1001781	1001804	4	-	28162770	TF1	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10341994
1002103	1002126	4	+	28162770	TF1	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10341995
1002315	1002338	4	-	28162770	TF1	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	NaN	[NaN]	[733]	1	hSpCas9	negative selection	10341996
1002372	1002395	4	-	28162770	TF1	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	NaN	[NaN]	[188]	1	hSpCas9	negative selection	10341997
987869	987892	4	-	28162770	SKM1	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.16029630024453545	[122]	[242]	1	hSpCas9	negative selection	10511354
1002775	1002798	4	+	28162770	SKM1	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	1	[27]	[98]	8	hSpCas9	negative selection	10511355
1002897	1002920	4	+	28162770	SKM1	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	0.04473177111453053	[84]	[154]	0	hSpCas9	negative selection	10511356
1000903	1000926	4	-	28162770	SKM1	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.3776706468143589	[63]	[146]	3	hSpCas9	negative selection	10511357
1001749	1001772	4	-	28162770	SKM1	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	0.07416249099345451	[71]	[133]	0	hSpCas9	negative selection	10511358
1001771	1001794	4	-	28162770	SKM1	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	0.21362221170871587	[19]	[40]	2	hSpCas9	negative selection	10511359
1001781	1001804	4	-	28162770	SKM1	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	0.40039072331444236	[8]	[20]	4	hSpCas9	negative selection	10511360
1002103	1002126	4	+	28162770	SKM1	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	0.2934755193979308	[23]	[51]	3	hSpCas9	negative selection	10511361
1002315	1002338	4	-	28162770	SKM1	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	0.7295746342046041	[101]	[298]	7	hSpCas9	negative selection	10511362
1002372	1002395	4	-	28162770	SKM1	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	0.1270143732591894	[71]	[138]	1	hSpCas9	negative selection	10511363
987869	987892	4	-	28162770	SKM1	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.16029630024453545	[122]	[242]	1	hSpCas9	negative selection	10680720
1002775	1002798	4	+	28162770	SKM1	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	1	[27]	[98]	8	hSpCas9	negative selection	10680721
1002897	1002920	4	+	28162770	SKM1	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	0.04473177111453053	[84]	[154]	0	hSpCas9	negative selection	10680722
1000903	1000926	4	-	28162770	SKM1	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.3776706468143589	[63]	[146]	3	hSpCas9	negative selection	10680723
1001749	1001772	4	-	28162770	SKM1	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	0.07416249099345451	[71]	[133]	0	hSpCas9	negative selection	10680724
1001771	1001794	4	-	28162770	SKM1	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	0.21362221170871587	[19]	[40]	2	hSpCas9	negative selection	10680725
1001781	1001804	4	-	28162770	SKM1	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	0.40039072331444236	[8]	[20]	4	hSpCas9	negative selection	10680726
1002103	1002126	4	+	28162770	SKM1	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	0.2934755193979308	[23]	[51]	3	hSpCas9	negative selection	10680727
1002315	1002338	4	-	28162770	SKM1	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	0.7295746342046041	[101]	[298]	7	hSpCas9	negative selection	10680728
1002372	1002395	4	-	28162770	SKM1	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	0.1270143732591894	[71]	[138]	1	hSpCas9	negative selection	10680729
987869	987892	4	-	28162770	PL21	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.5417149518271431	[422]	[267]	5	hSpCas9	negative selection	10850086
1002775	1002798	4	+	28162770	PL21	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	0.29156264225291506	[106]	[56]	2	hSpCas9	negative selection	10850087
1002897	1002920	4	+	28162770	PL21	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	-0.11056122497478793	[319]	[128]	-1	hSpCas9	negative selection	10850088
1000903	1000926	4	-	28162770	PL21	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.43091982131848705	[195]	[114]	4	hSpCas9	negative selection	10850089
1001749	1001772	4	-	28162770	PL21	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	-0.06090623825101982	[289]	[120]	0	hSpCas9	negative selection	10850090
1001771	1001794	4	-	28162770	PL21	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	0.21701343305371623	[84]	[42]	2	hSpCas9	negative selection	10850091
1001781	1001804	4	-	28162770	PL21	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	0.9631004171884705	[32]	[27]	7	hSpCas9	negative selection	10850092
1002103	1002126	4	+	28162770	PL21	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	-0.40252488796529495	[81]	[26]	-3	hSpCas9	negative selection	10850093
1002315	1002338	4	-	28162770	PL21	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	0.5596820011764604	[370]	[237]	5	hSpCas9	negative selection	10850094
1002372	1002395	4	-	28162770	PL21	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	0.8276625774385222	[166]	[128]	7	hSpCas9	negative selection	10850095
987869	987892	4	-	28162770	P31FUJ	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	-0.15744852241100982	[372]	[392]	-1	hSpCas9	negative selection	11019452
1002775	1002798	4	+	28162770	P31FUJ	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	-0.7641267415334616	[197]	[136]	-5	hSpCas9	negative selection	11019453
1002897	1002920	4	+	28162770	P31FUJ	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	0.2199124980083379	[273]	[374]	2	hSpCas9	negative selection	11019454
1000903	1000926	4	-	28162770	P31FUJ	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.03467810645060726	[161]	[194]	0	hSpCas9	negative selection	11019455
1001749	1001772	4	-	28162770	P31FUJ	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	0.2707719694661225	[236]	[335]	3	hSpCas9	negative selection	11019456
1001771	1001794	4	-	28162770	P31FUJ	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	0.9449849148009041	[60]	[137]	9	hSpCas9	negative selection	11019457
1001781	1001804	4	-	28162770	P31FUJ	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	0.04182017569462726	[61]	[74]	0	hSpCas9	negative selection	11019458
1002103	1002126	4	+	28162770	P31FUJ	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	0.17419797579904683	[134]	[178]	1	hSpCas9	negative selection	11019459
1002315	1002338	4	-	28162770	P31FUJ	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	0.6302168927582243	[413]	[752]	7	hSpCas9	negative selection	11019460
1002372	1002395	4	-	28162770	P31FUJ	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	0.7478972396266852	[300]	[593]	8	hSpCas9	negative selection	11019461
987869	987892	4	-	28162770	OCIAML5	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.07523023540635865	[233]	[444]	0	hSpCas9	negative selection	11188818
1002775	1002798	4	+	28162770	OCIAML5	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	0.8379779759147167	[74]	[241]	7	hSpCas9	negative selection	11188819
1002897	1002920	4	+	28162770	OCIAML5	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	0.17869568290669002	[115]	[236]	1	hSpCas9	negative selection	11188820
1000903	1000926	4	-	28162770	OCIAML5	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.637738696816819	[93]	[263]	5	hSpCas9	negative selection	11188821
1001749	1001772	4	-	28162770	OCIAML5	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	0.10682822580632984	[88]	[172]	0	hSpCas9	negative selection	11188822
1001771	1001794	4	-	28162770	OCIAML5	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	1.2128888709767731	[37]	[158]	8	hSpCas9	negative selection	11188823
1001781	1001804	4	-	28162770	OCIAML5	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	1.8848990233022094	[29]	[199]	9	hSpCas9	negative selection	11188824
1002103	1002126	4	+	28162770	OCIAML5	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	-0.6925883568568005	[76]	[85]	-4	hSpCas9	negative selection	11188825
1002315	1002338	4	-	28162770	OCIAML5	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	0.7083629181132165	[256]	[757]	6	hSpCas9	negative selection	11188826
1002372	1002395	4	-	28162770	OCIAML5	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	0.7913422022407163	[128]	[402]	7	hSpCas9	negative selection	11188827
987869	987892	4	-	28162770	EOL1	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.8268510976834014	[671]	[627]	7	hSpCas9	negative selection	11358184
1002775	1002798	4	+	28162770	EOL1	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	0.6905905986011643	[166]	[141]	6	hSpCas9	negative selection	11358185
1002897	1002920	4	+	28162770	EOL1	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	-0.11966493376179	[496]	[240]	-1	hSpCas9	negative selection	11358186
1000903	1000926	4	-	28162770	EOL1	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	-0.04374336870212724	[314]	[160]	0	hSpCas9	negative selection	11358187
1001749	1001772	4	-	28162770	EOL1	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	-1.1544035698242872	[506]	[119]	-6	hSpCas9	negative selection	11358188
1001771	1001794	4	-	28162770	EOL1	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	0.13605187676424624	[94]	[54]	1	hSpCas9	negative selection	11358189
1001781	1001804	4	-	28162770	EOL1	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	-0.3164603279332603	[51]	[21]	-2	hSpCas9	negative selection	11358190
1002103	1002126	4	+	28162770	EOL1	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	-1.0519932556054765	[121]	[30]	-6	hSpCas9	negative selection	11358191
1002315	1002338	4	-	28162770	EOL1	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	-0.17267403614213334	[444]	[207]	-1	hSpCas9	negative selection	11358192
1002372	1002395	4	-	28162770	EOL1	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	0.220622439168336	[258]	[158]	2	hSpCas9	negative selection	11358193
987869	987892	4	-	28162770	MOLM13	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.5631064488980515	[512]	[547]	4	hSpCas9	negative selection	11527550
1002775	1002798	4	+	28162770	MOLM13	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	0.3015309951224588	[201]	[179]	2	hSpCas9	negative selection	11527551
1002897	1002920	4	+	28162770	MOLM13	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	0.7429966196789476	[356]	[431]	5	hSpCas9	negative selection	11527552
1000903	1000926	4	-	28162770	MOLM13	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.5538626046544317	[227]	[241]	4	hSpCas9	negative selection	11527553
1001749	1001772	4	-	28162770	MOLM13	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	0.3056179526457017	[328]	[293]	2	hSpCas9	negative selection	11527554
1001771	1001794	4	-	28162770	MOLM13	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	1.6254306585310592	[51]	[115]	9	hSpCas9	negative selection	11527555
1001781	1001804	4	-	28162770	MOLM13	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	1.412394268952875	[52]	[101]	9	hSpCas9	negative selection	11527556
1002103	1002126	4	+	28162770	MOLM13	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	-0.13697267661428214	[145]	[95]	-1	hSpCas9	negative selection	11527557
1002315	1002338	4	-	28162770	MOLM13	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	0.5274781778343788	[497]	[518]	4	hSpCas9	negative selection	11527558
1002372	1002395	4	-	28162770	MOLM13	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	-0.7980046784284557	[302]	[125]	-4	hSpCas9	negative selection	11527559
987869	987892	4	-	28162770	HEL	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	1.0911769030307985	[490]	[669]	8	hSpCas9	negative selection	11696916
1002775	1002798	4	+	28162770	HEL	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	-0.17892392674113067	[151]	[85]	-1	hSpCas9	negative selection	11696917
1002897	1002920	4	+	28162770	HEL	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	0.43514341259198974	[387]	[335]	3	hSpCas9	negative selection	11696918
1000903	1000926	4	-	28162770	HEL	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	1.178553683392425	[208]	[302]	9	hSpCas9	negative selection	11696919
1001749	1001772	4	-	28162770	HEL	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	0.40894164739165956	[253]	[215]	3	hSpCas9	negative selection	11696920
1001771	1001794	4	-	28162770	HEL	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	0.12190666869891653	[65]	[45]	1	hSpCas9	negative selection	11696921
1001781	1001804	4	-	28162770	HEL	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	2.061451989422599	[48]	[130]	9	hSpCas9	negative selection	11696922
1002103	1002126	4	+	28162770	HEL	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	0.6087915000770192	[128]	[125]	5	hSpCas9	negative selection	11696923
1002315	1002338	4	-	28162770	HEL	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	-0.0849885553105113	[466]	[281]	0	hSpCas9	negative selection	11696924
1002372	1002395	4	-	28162770	HEL	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	0.5394510235883349	[274]	[255]	4	hSpCas9	negative selection	11696925
987869	987892	4	-	28162770	MV411	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.7285074247257095	[378]	[528]	6	hSpCas9	negative selection	11866282
1002775	1002798	4	+	28162770	MV411	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	0.6590684486183696	[105]	[140]	6	hSpCas9	negative selection	11866283
1002897	1002920	4	+	28162770	MV411	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	0.22006111185147026	[265]	[260]	2	hSpCas9	negative selection	11866284
1000903	1000926	4	-	28162770	MV411	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	-0.413977010376254	[154]	[97]	-3	hSpCas9	negative selection	11866285
1001749	1001772	4	-	28162770	MV411	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	-0.25760140564143164	[236]	[166]	-2	hSpCas9	negative selection	11866286
1001771	1001794	4	-	28162770	MV411	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	-1.159737830723098	[60]	[22]	-6	hSpCas9	negative selection	11866287
1001781	1001804	4	-	28162770	MV411	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	-1.3051034722460035	[43]	[14]	-7	hSpCas9	negative selection	11866288
1002103	1002126	4	+	28162770	MV411	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	0.6202468146723218	[77]	[100]	5	hSpCas9	negative selection	11866289
1002315	1002338	4	-	28162770	MV411	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	1.0745037994681246	[269]	[478]	8	hSpCas9	negative selection	11866290
1002372	1002395	4	-	28162770	MV411	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	0.27478803892773085	[208]	[212]	2	hSpCas9	negative selection	11866291
987869	987892	4	-	28162770	MONOMAC1	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.13003455110376838	[223]	[280]	1	hSpCas9	negative selection	12035648
1002775	1002798	4	+	28162770	MONOMAC1	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	-1.0485143223494655	[82]	[45]	-7	hSpCas9	negative selection	12035649
1002897	1002920	4	+	28162770	MONOMAC1	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	0.6336087249842695	[157]	[280]	6	hSpCas9	negative selection	12035650
1000903	1000926	4	-	28162770	MONOMAC1	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.11805921434538352	[126]	[157]	1	hSpCas9	negative selection	12035651
1001749	1001772	4	-	28162770	MONOMAC1	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	-0.5955862235498286	[144]	[109]	-5	hSpCas9	negative selection	12035652
1001771	1001794	4	-	28162770	MONOMAC1	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	0.18147477619417596	[39]	[51]	1	hSpCas9	negative selection	12035653
1001781	1001804	4	-	28162770	MONOMAC1	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	-1.9813081560041164	[30]	[8]	-8	hSpCas9	negative selection	12035654
1002103	1002126	4	+	28162770	MONOMAC1	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	0.05350661459104322	[57]	[68]	0	hSpCas9	negative selection	12035655
1002315	1002338	4	-	28162770	MONOMAC1	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	0.4817769943208574	[242]	[388]	5	hSpCas9	negative selection	12035656
1002372	1002395	4	-	28162770	MONOMAC1	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	0.5399287471066525	[128]	[214]	5	hSpCas9	negative selection	12035657
987869	987892	4	-	28162770	OCIAML2	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	-0.40942966880542364	[74]	[312]	-3	hSpCas9	negative selection	12205014
1002775	1002798	4	+	28162770	OCIAML2	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	1.1398677675861324	[13]	[170]	9	hSpCas9	negative selection	12205015
1002897	1002920	4	+	28162770	OCIAML2	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	0.6147616659884834	[40]	[347]	6	hSpCas9	negative selection	12205016
1000903	1000926	4	-	28162770	OCIAML2	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.323366713960424	[30]	[214]	3	hSpCas9	negative selection	12205017
1001749	1001772	4	-	28162770	OCIAML2	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	-0.1811232080471765	[44]	[219]	-1	hSpCas9	negative selection	12205018
1001771	1001794	4	-	28162770	OCIAML2	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	0.261174063808266	[13]	[92]	2	hSpCas9	negative selection	12205019
1001781	1001804	4	-	28162770	OCIAML2	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	1.2481884222137856	[5]	[78]	9	hSpCas9	negative selection	12205020
1002103	1002126	4	+	28162770	OCIAML2	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	0.8798674218419721	[9]	[101]	8	hSpCas9	negative selection	12205021
1002315	1002338	4	-	28162770	OCIAML2	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	0.45274889315492617	[57]	[439]	4	hSpCas9	negative selection	12205022
1002372	1002395	4	-	28162770	OCIAML2	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	0.2580681529404444	[34]	[231]	2	hSpCas9	negative selection	12205023
987869	987892	4	-	28162770	OCIAML3	viability	GGACGGCGCCCACATAGGCGAGG	IDUA	ENSG00000127415	0.32495578758493027	[118]	[449]	3	hSpCas9	negative selection	12374380
1002775	1002798	4	+	28162770	OCIAML3	viability	CCTGGACAGCAACCACACGGTGG	IDUA	ENSG00000127415	0.3620490120882396	[24]	[96]	3	hSpCas9	negative selection	12374381
1002897	1002920	4	+	28162770	OCIAML3	viability	GCAGCGTCGCGGTGACCCTGCGG	IDUA	ENSG00000127415	-0.0021914685619442986	[69]	[210]	0	hSpCas9	negative selection	12374382
1000903	1000926	4	-	28162770	OCIAML3	viability	AAAGTCAGTGAAGTGGCCCGAGG	IDUA	ENSG00000127415	0.048440355057753126	[40]	[127]	0	hSpCas9	negative selection	12374383
1001749	1001772	4	-	28162770	OCIAML3	viability	GGGTGTGGAAGGAGTCGCCGGGG	IDUA	ENSG00000127415	0.6430315569766862	[48]	[230]	6	hSpCas9	negative selection	12374384
1001771	1001794	4	-	28162770	OCIAML3	viability	CAGCTCAGCGGGGATCGCGGTGG	IDUA	ENSG00000127415	0.405992359675837	[15]	[63]	4	hSpCas9	negative selection	12374385
1001781	1001804	4	-	28162770	OCIAML3	viability	CAGGAGGCCCCAGCTCAGCGGGG	IDUA	ENSG00000127415	2.4119911002972803	[14]	[240]	9	hSpCas9	negative selection	12374386
1002103	1002126	4	+	28162770	OCIAML3	viability	GCTGGTCCCTGCCACAGCCGTGG	IDUA	ENSG00000127415	0.36946648365072265	[19]	[77]	3	hSpCas9	negative selection	12374387
1002315	1002338	4	-	28162770	OCIAML3	viability	GCTCAGGAGCGCGTAGGGGAAGG	IDUA	ENSG00000127415	0.4459185440885959	[97]	[402]	4	hSpCas9	negative selection	12374388
1002372	1002395	4	-	28162770	OCIAML3	viability	GGTGAGCGTGCGCTGCGCGAAGG	IDUA	ENSG00000127415	0.4416162694065583	[59]	[245]	4	hSpCas9	negative selection	12374389