Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 387755
• Symbol: INSC
• Description: INSC spindle orientation adaptor protein

DataSource: http://genomecrispr.dkfz.de/#!/results/INSC

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
15175768	15175791	11	-	26472758	Jiyoye	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	0.3131318915907356	[205]	[192]	2	hSpCas9	negative selection	78477
15175954	15175977	11	+	26472758	Jiyoye	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	1.5507662351347231	[42]	[94]	8	hSpCas9	negative selection	78478
15175932	15175955	11	+	26472758	Jiyoye	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.2728343278482566	[148]	[92]	-2	hSpCas9	negative selection	78479
15178345	15178368	11	+	26472758	Jiyoye	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	1.1658905590625346	[236]	[400]	7	hSpCas9	negative selection	78480
15178420	15178443	11	+	26472758	Jiyoye	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.38699749956824314	[71]	[70]	3	hSpCas9	negative selection	78481
15221571	15221594	11	-	26472758	Jiyoye	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-0.5928246184941273	[1]	[0]	-4	hSpCas9	negative selection	78482
15225692	15225715	11	-	26472758	Jiyoye	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	-0.04920291315386979	[117]	[85]	0	hSpCas9	negative selection	78483
15149172	15149195	11	+	26472758	Jiyoye	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	0.07596947303050017	[77]	[61]	0	hSpCas9	negative selection	78484
15149198	15149221	11	-	26472758	Jiyoye	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	-0.06371535250648797	[78]	[56]	0	hSpCas9	negative selection	78485
15175901	15175924	11	-	26472758	Jiyoye	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	-0.07825144566436848	[216]	[154]	0	hSpCas9	negative selection	78486
15175768	15175791	11	-	26472758	KBM7	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	0.3944860268495062	[1009,677]	[566,465]	4	hSpCas9	negative selection	269595
15175954	15175977	11	+	26472758	KBM7	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	0.19576844718976918	[416,303]	[201,182]	2	hSpCas9	negative selection	269596
15175932	15175955	11	+	26472758	KBM7	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.032978857056188304	[503,506]	[289,182]	0	hSpCas9	negative selection	269597
15178345	15178368	11	+	26472758	KBM7	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.5150681022659838	[1590,1558]	[1074,1050]	5	hSpCas9	negative selection	269598
15178420	15178443	11	+	26472758	KBM7	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.795354201736767	[110,145]	[43,162]	8	hSpCas9	negative selection	269599
15221571	15221594	11	-	26472758	KBM7	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-3.0339733911653637	[94,57]	[7,0]	-9	hSpCas9	negative selection	269600
15225692	15225715	11	-	26472758	KBM7	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	1.0415670525332266	[344,264]	[194,379]	9	hSpCas9	negative selection	269601
15149172	15149195	11	+	26472758	KBM7	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	0.8947094570554748	[280,261]	[215,256]	8	hSpCas9	negative selection	269602
15149198	15149221	11	-	26472758	KBM7	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.3840036780297517	[307,302]	[89,275]	4	hSpCas9	negative selection	269603
15175901	15175924	11	-	26472758	KBM7	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	0.4446034534126815	[893,651]	[448,524]	5	hSpCas9	negative selection	269604
15175768	15175791	11	-	26472758	Raji	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	0.7950414893154352	[374]	[150]	7	hSpCas9	negative selection	460713
15175954	15175977	11	+	26472758	Raji	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	0.6293362385689553	[155]	[55]	6	hSpCas9	negative selection	460714
15175932	15175955	11	+	26472758	Raji	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	1.3356525230467167	[139]	[81]	9	hSpCas9	negative selection	460715
15178345	15178368	11	+	26472758	Raji	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.5037752818550434	[622]	[204]	5	hSpCas9	negative selection	460716
15178420	15178443	11	+	26472758	Raji	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.14055039930879887	[85]	[21]	1	hSpCas9	negative selection	460717
15221571	15221594	11	-	26472758	Raji	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-3.284933887405161	[41]	[0]	-9	hSpCas9	negative selection	460718
15225692	15225715	11	-	26472758	Raji	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	0.37557964632317214	[185]	[55]	3	hSpCas9	negative selection	460719
15149172	15149195	11	+	26472758	Raji	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	0.5652341181914164	[165]	[56]	5	hSpCas9	negative selection	460720
15149198	15149221	11	-	26472758	Raji	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.5224210346524434	[161]	[53]	5	hSpCas9	negative selection	460721
15175901	15175924	11	-	26472758	Raji	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	-0.26607486015384485	[512]	[98]	-2	hSpCas9	negative selection	460722
15175768	15175791	11	-	26472758	K562	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	0.8929906163659344	[561]	[880]	7	hSpCas9	negative selection	651831
15175954	15175977	11	+	26472758	K562	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	-0.1630055875025217	[251]	[189]	-1	hSpCas9	negative selection	651832
15175932	15175955	11	+	26472758	K562	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.18480923852829167	[419]	[402]	1	hSpCas9	negative selection	651833
15178345	15178368	11	+	26472758	K562	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.9822759751619563	[1293]	[2157]	8	hSpCas9	negative selection	651834
15178420	15178443	11	+	26472758	K562	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.4015196887511756	[112]	[125]	3	hSpCas9	negative selection	651835
15221571	15221594	11	-	26472758	K562	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-5.510468774497021	[53]	[0]	-9	hSpCas9	negative selection	651836
15225692	15225715	11	-	26472758	K562	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	0.10275757844285577	[277]	[251]	0	hSpCas9	negative selection	651837
15149172	15149195	11	+	26472758	K562	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	-0.1469027026385894	[180]	[137]	-1	hSpCas9	negative selection	651838
15149198	15149221	11	-	26472758	K562	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	-0.017073513358941472	[186]	[155]	0	hSpCas9	negative selection	651839
15175901	15175924	11	-	26472758	K562	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	0.4156053776726707	[634]	[714]	3	hSpCas9	negative selection	651840
15112488	15112511	11	+	26627737	DLD1	viability	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	-0.8082783870629541	[525]	[104,121,60]	-6	hSpCas9	negative selection	777746
15149216	15149239	11	-	26627737	DLD1	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.8118427422009429	[103]	[41,84,46]	7	hSpCas9	negative selection	777747
15175738	15175761	11	+	26627737	DLD1	viability	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-0.0041708292097096256	[510]	[145,158,170]	0	hSpCas9	negative selection	777748
15178368	15178391	11	-	26627737	DLD1	viability	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	1.350457605883081	[526]	[362,375,505]	9	hSpCas9	negative selection	777749
15190792	15190815	11	-	26627737	DLD1	viability	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	0.7976424936760763	[705]	[268,391,475]	7	hSpCas9	negative selection	777750
15200841	15200864	11	+	26627737	DLD1	viability	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	-0.2211936597469013	[204]	[42,87,37]	-2	hSpCas9	negative selection	777751
15112488	15112511	11	+	26627737	GBM cells	viability after 5 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	1.7834366574657496	[51]	[85,105]	9	hSpCas9	negative selection	860061
15149216	15149239	11	-	26627737	GBM cells	viability after 5 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-0.3371534833478389	[52]	[24,19]	-5	hSpCas9	negative selection	860062
15175738	15175761	11	+	26627737	GBM cells	viability after 5 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	0.023900651724215655	[220]	[120,119]	0	hSpCas9	negative selection	860063
15178368	15178391	11	-	26627737	GBM cells	viability after 5 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	0.7293167214258974	[274]	[269,218]	8	hSpCas9	negative selection	860064
15190792	15190815	11	-	26627737	GBM cells	viability after 5 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	0.2101875773083841	[298]	[169,200]	3	hSpCas9	negative selection	860065
15200841	15200864	11	+	26627737	GBM cells	viability after 5 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	0.37284506321809774	[89]	[78,45]	6	hSpCas9	negative selection	860066
15112488	15112511	11	+	26627737	GBM cells	viability after 13 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	2.063587085529299	[51]	[139,99]	9	hSpCas9	negative selection	942376
15149216	15149239	11	-	26627737	GBM cells	viability after 13 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-0.01740079339931766	[52]	[23,31]	0	hSpCas9	negative selection	942377
15175738	15175761	11	+	26627737	GBM cells	viability after 13 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	0.06853079326153702	[220]	[165,92]	0	hSpCas9	negative selection	942378
15178368	15178391	11	-	26627737	GBM cells	viability after 13 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	1.2051417432698748	[274]	[300,378]	9	hSpCas9	negative selection	942379
15190792	15190815	11	-	26627737	GBM cells	viability after 13 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	0.3215025825167583	[298]	[210,195]	4	hSpCas9	negative selection	942380
15200841	15200864	11	+	26627737	GBM cells	viability after 13 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	0.8877496867195894	[89]	[107,75]	9	hSpCas9	negative selection	942381
15112488	15112511	11	+	26627737	GBM cells	viability after 21 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	2.1052656028248107	[51]	[131,111]	9	hSpCas9	negative selection	1024691
15149216	15149239	11	-	26627737	GBM cells	viability after 21 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-0.8719347011942178	[52]	[21,9]	-6	hSpCas9	negative selection	1024692
15175738	15175761	11	+	26627737	GBM cells	viability after 21 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	0.5136475600173087	[220]	[149,190]	5	hSpCas9	negative selection	1024693
15178368	15178391	11	-	26627737	GBM cells	viability after 21 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	1.565609453356076	[274]	[471,414]	9	hSpCas9	negative selection	1024694
15190792	15190815	11	-	26627737	GBM cells	viability after 21 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	0.5002573297871091	[298]	[246,213]	5	hSpCas9	negative selection	1024695
15200841	15200864	11	+	26627737	GBM cells	viability after 21 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	0.05102880082107397	[89]	[46,53]	0	hSpCas9	negative selection	1024696
15112488	15112511	11	+	26627737	RPE1	viability after 9 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	-0.9698913805462224	[932]	[149,147]	-6	hSpCas9	negative selection	1107006
15149216	15149239	11	-	26627737	RPE1	viability after 9 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.7985451583995011	[215]	[145,80]	5	hSpCas9	negative selection	1107007
15175738	15175761	11	+	26627737	RPE1	viability after 9 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-1.1435215767202342	[974]	[97,189]	-7	hSpCas9	negative selection	1107008
15178368	15178391	11	-	26627737	RPE1	viability after 9 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	0.7278758460349287	[837]	[282,629]	5	hSpCas9	negative selection	1107009
15190792	15190815	11	-	26627737	RPE1	viability after 9 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	1.6138777985580326	[414]	[384,413]	8	hSpCas9	negative selection	1107010
15200841	15200864	11	+	26627737	RPE1	viability after 9 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	-0.8255126597195459	[1062]	[237,122]	-5	hSpCas9	negative selection	1107011
15112488	15112511	11	+	26627737	RPE1	viability after 12 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	-2.70444218151327	[932]	[53,21]	-9	hSpCas9	negative selection	1189321
15149216	15149239	11	-	26627737	RPE1	viability after 12 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.9086517082908175	[215]	[89,128]	5	hSpCas9	negative selection	1189322
15175738	15175761	11	+	26627737	RPE1	viability after 12 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-1.1003838761883111	[974]	[178,61]	-6	hSpCas9	negative selection	1189323
15178368	15178391	11	-	26627737	RPE1	viability after 12 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	0.9236868094095645	[837]	[276,585]	6	hSpCas9	negative selection	1189324
15190792	15190815	11	-	26627737	RPE1	viability after 12 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	1.2402554208080028	[414]	[293,230]	7	hSpCas9	negative selection	1189325
15200841	15200864	11	+	26627737	RPE1	viability after 12 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	-1.2892123589738222	[1062]	[77,157]	-7	hSpCas9	negative selection	1189326
15112488	15112511	11	+	26627737	RPE1	viability after 15 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	-1.3257653654787056	[932]	[88,120]	-7	hSpCas9	negative selection	1271636
15149216	15149239	11	-	26627737	RPE1	viability after 15 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	1.049493666206013	[215]	[71,178]	6	hSpCas9	negative selection	1271637
15175738	15175761	11	+	26627737	RPE1	viability after 15 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-1.4461022123692147	[974]	[172,31]	-7	hSpCas9	negative selection	1271638
15178368	15178391	11	-	26627737	RPE1	viability after 15 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	0.7809176909111496	[837]	[389,423]	5	hSpCas9	negative selection	1271639
15190792	15190815	11	-	26627737	RPE1	viability after 15 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	2.030474640717881	[414]	[501,457]	8	hSpCas9	negative selection	1271640
15200841	15200864	11	+	26627737	RPE1	viability after 15 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	-1.458254649717417	[1062]	[84,132]	-7	hSpCas9	negative selection	1271641
15112488	15112511	11	+	26627737	RPE1	viability after 18 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	-2.538554511243723	[932]	[23,63]	-8	hSpCas9	negative selection	1353951
15149216	15149239	11	-	26627737	RPE1	viability after 18 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.9154565676610775	[215]	[122,95]	5	hSpCas9	negative selection	1353952
15175738	15175761	11	+	26627737	RPE1	viability after 18 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-1.4830386934016733	[974]	[126,58]	-7	hSpCas9	negative selection	1353953
15178368	15178391	11	-	26627737	RPE1	viability after 18 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	1.1102435306854872	[837]	[479,496]	6	hSpCas9	negative selection	1353954
15190792	15190815	11	-	26627737	RPE1	viability after 18 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	1.5422675911650099	[414]	[287,366]	7	hSpCas9	negative selection	1353955
15200841	15200864	11	+	26627737	RPE1	viability after 18 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	-1.005965013652361	[1062]	[79,209]	-6	hSpCas9	negative selection	1353956
15112488	15112511	11	+	26627737	HeLa	viability after 8 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	1.0048524211768386	[284]	[145,240,330]	7	hSpCas9	negative selection	1436266
15149216	15149239	11	-	26627737	HeLa	viability after 8 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-1.8549060565291606	[181]	[26,5,32]	-9	hSpCas9	negative selection	1436267
15175738	15175761	11	+	26627737	HeLa	viability after 8 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	0.5652505852360199	[301]	[233,177,180]	5	hSpCas9	negative selection	1436268
15178368	15178391	11	-	26627737	HeLa	viability after 8 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	-0.1115777158253739	[816]	[362,337,295]	-1	hSpCas9	negative selection	1436269
15190792	15190815	11	-	26627737	HeLa	viability after 8 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	0.8092699741508369	[331]	[353,327,109]	6	hSpCas9	negative selection	1436270
15200841	15200864	11	+	26627737	HeLa	viability after 8 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	2.423388825567458	[26]	[93,84,19]	9	hSpCas9	negative selection	1436271
15112488	15112511	11	+	26627737	HeLa	viability after 12 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	0.5521648030157693	[284]	[291,111,123]	4	hSpCas9	negative selection	1518581
15149216	15149239	11	-	26627737	HeLa	viability after 12 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-1.8656085870341226	[181]	[6,34,17]	-9	hSpCas9	negative selection	1518582
15175738	15175761	11	+	26627737	HeLa	viability after 12 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	0.32890254001641256	[301]	[145,165,156]	3	hSpCas9	negative selection	1518583
15178368	15178391	11	-	26627737	HeLa	viability after 12 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	-0.12973145348239457	[816]	[231,398,282]	-1	hSpCas9	negative selection	1518584
15190792	15190815	11	-	26627737	HeLa	viability after 12 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	0.5331227672595285	[331]	[202,233,154]	4	hSpCas9	negative selection	1518585
15200841	15200864	11	+	26627737	HeLa	viability after 12 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	3.1720163434273303	[26]	[31,229,23]	9	hSpCas9	negative selection	1518586
15112488	15112511	11	+	26627737	HeLa	viability after 15 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	0.14218834632359778	[284]	[8,159,223]	1	hSpCas9	negative selection	1600896
15149216	15149239	11	-	26627737	HeLa	viability after 15 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-1.0863641975519887	[181]	[39,12,52]	-7	hSpCas9	negative selection	1600897
15175738	15175761	11	+	26627737	HeLa	viability after 15 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	0.4996625887310893	[301]	[267,117,130]	4	hSpCas9	negative selection	1600898
15178368	15178391	11	-	26627737	HeLa	viability after 15 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	-0.5868635418581987	[816]	[119,343,199]	-5	hSpCas9	negative selection	1600899
15190792	15190815	11	-	26627737	HeLa	viability after 15 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	1.4921495968062586	[331]	[277,301,576]	8	hSpCas9	negative selection	1600900
15200841	15200864	11	+	26627737	HeLa	viability after 15 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	2.7122696482027493	[26]	[99,100,9]	9	hSpCas9	negative selection	1600901
15112488	15112511	11	+	26627737	HeLa	viability after 18 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	0.16844319613790049	[284]	[6,136,223]	1	hSpCas9	negative selection	1683211
15149216	15149239	11	-	26627737	HeLa	viability after 18 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-1.0209198899295453	[181]	[28,11,52]	-7	hSpCas9	negative selection	1683212
15175738	15175761	11	+	26627737	HeLa	viability after 18 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	0.5200621881065686	[301]	[185,95,130]	4	hSpCas9	negative selection	1683213
15178368	15178391	11	-	26627737	HeLa	viability after 18 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	-0.6505066876183664	[816]	[72,270,199]	-5	hSpCas9	negative selection	1683214
15190792	15190815	11	-	26627737	HeLa	viability after 18 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	1.4878907580706497	[331]	[177,257,576]	8	hSpCas9	negative selection	1683215
15200841	15200864	11	+	26627737	HeLa	viability after 18 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	2.7468464310919645	[26]	[70,82,9]	9	hSpCas9	negative selection	1683216
15112488	15112511	11	+	26627737	HCT116	viability after 6 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	1.6490284962273947	[453]	[121,279]	8	hSpCas9	negative selection	1765526
15149216	15149239	11	-	26627737	HCT116	viability after 6 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-0.4330352769830572	[78]	[14,5]	-2	hSpCas9	negative selection	1765527
15175738	15175761	11	+	26627737	HCT116	viability after 6 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-0.29960187699780827	[564]	[144,31]	-2	hSpCas9	negative selection	1765528
15178368	15178391	11	-	26627737	HCT116	viability after 6 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	0.5457319694064423	[1124]	[301,233]	3	hSpCas9	negative selection	1765529
15190792	15190815	11	-	26627737	HCT116	viability after 6 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	0.8723816580221065	[621]	[256,135]	5	hSpCas9	negative selection	1765530
15200841	15200864	11	+	26627737	HCT116	viability after 6 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	2.4227199285503493	[213]	[6,275]	9	hSpCas9	negative selection	1765531
15112488	15112511	11	+	26627737	HCT116	viability after 8 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	1.2491117917726595	[130]	[187,152,173]	8	hSpCas9	negative selection	1847841
15149216	15149239	11	-	26627737	HCT116	viability after 8 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.9668793218877139	[65]	[96,68,47]	8	hSpCas9	negative selection	1847842
15175738	15175761	11	+	26627737	HCT116	viability after 8 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-0.7111806685963512	[428]	[191,177,64]	-7	hSpCas9	negative selection	1847843
15178368	15178391	11	-	26627737	HCT116	viability after 8 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	-1.0251459228358208	[859]	[248,230,218]	-8	hSpCas9	negative selection	1847844
15190792	15190815	11	-	26627737	HCT116	viability after 8 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	0.8590870030794412	[279]	[344,236,258]	7	hSpCas9	negative selection	1847845
15200841	15200864	11	+	26627737	HCT116	viability after 8 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	0.07344417437365358	[118]	[61,86,57]	0	hSpCas9	negative selection	1847846
15112488	15112511	11	+	26627737	HCT116	viability after 9 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	0.14579089130366085	[453]	[194,85]	1	hSpCas9	negative selection	1930156
15149216	15149239	11	-	26627737	HCT116	viability after 9 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-0.11172336508006664	[78]	[4,30]	-1	hSpCas9	negative selection	1930157
15175738	15175761	11	+	26627737	HCT116	viability after 9 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	0.8923050205535327	[564]	[336,234]	6	hSpCas9	negative selection	1930158
15178368	15178391	11	-	26627737	HCT116	viability after 9 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	0.2216794681912736	[1124]	[337,359]	1	hSpCas9	negative selection	1930159
15190792	15190815	11	-	26627737	HCT116	viability after 9 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	0.8166673699924849	[621]	[358,239]	6	hSpCas9	negative selection	1930160
15200841	15200864	11	+	26627737	HCT116	viability after 9 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	-0.14506373269587947	[213]	[111,3]	-1	hSpCas9	negative selection	1930161
15112488	15112511	11	+	26627737	HCT116	viability after 12 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	1.2757088092136744	[130]	[97,286,123]	8	hSpCas9	negative selection	2012471
15149216	15149239	11	-	26627737	HCT116	viability after 12 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	1.3478790507152385	[65]	[98,132,32]	9	hSpCas9	negative selection	2012472
15175738	15175761	11	+	26627737	HCT116	viability after 12 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-0.9967915292534136	[428]	[104,86,146]	-8	hSpCas9	negative selection	2012473
15178368	15178391	11	-	26627737	HCT116	viability after 12 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	-0.6959933266922445	[859]	[277,194,361]	-6	hSpCas9	negative selection	2012474
15190792	15190815	11	-	26627737	HCT116	viability after 12 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	1.2143800796168736	[279]	[402,220,391]	8	hSpCas9	negative selection	2012475
15200841	15200864	11	+	26627737	HCT116	viability after 12 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	0.14537582353615264	[118]	[21,124,65]	1	hSpCas9	negative selection	2012476
15112488	15112511	11	+	26627737	HCT116	viability after 15 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	0.7137328973242274	[130]	[130,109,129]	6	hSpCas9	negative selection	2094786
15149216	15149239	11	-	26627737	HCT116	viability after 15 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	1.0597399093913822	[65]	[69,91,73]	8	hSpCas9	negative selection	2094787
15175738	15175761	11	+	26627737	HCT116	viability after 15 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-0.4753352533882112	[428]	[228,135,172]	-5	hSpCas9	negative selection	2094788
15178368	15178391	11	-	26627737	HCT116	viability after 15 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	-1.0837894342171672	[859]	[283,84,334]	-8	hSpCas9	negative selection	2094789
15190792	15190815	11	-	26627737	HCT116	viability after 15 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	1.0118714756620484	[279]	[426,375,183]	8	hSpCas9	negative selection	2094790
15200841	15200864	11	+	26627737	HCT116	viability after 15 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	0.31019345783598373	[118]	[38,154,54]	3	hSpCas9	negative selection	2094791
15112488	15112511	11	+	26627737	HCT116	viability after 18 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	1.2928932136002111	[130]	[160,182,117]	8	hSpCas9	negative selection	2177101
15149216	15149239	11	-	26627737	HCT116	viability after 18 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.9719644200564379	[65]	[36,130,12]	7	hSpCas9	negative selection	2177102
15175738	15175761	11	+	26627737	HCT116	viability after 18 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-0.76612485199596	[428]	[73,88,208]	-6	hSpCas9	negative selection	2177103
15178368	15178391	11	-	26627737	HCT116	viability after 18 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	-0.7133560452337222	[859]	[471,75,222]	-6	hSpCas9	negative selection	2177104
15190792	15190815	11	-	26627737	HCT116	viability after 18 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	0.5058048884127392	[279]	[254,128,196]	4	hSpCas9	negative selection	2177105
15200841	15200864	11	+	26627737	HCT116	viability after 18 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	-0.4663839945707351	[118]	[44,30,49]	-4	hSpCas9	negative selection	2177106
15149169	15149192	11	+	24336569	HL60	viability	ATCAACATGATGGCACTGCCTGG	INSC	ENSG00000188487	0.923776352066984	[686]	[2757]	7	hSpCas9	negative selection	2271745
15149183	15149206	11	+	24336569	HL60	viability	ACTGCCTGGAGGTCGCCACCTGG	INSC	ENSG00000188487	-0.6923181344820765	[758]	[993]	-6	hSpCas9	negative selection	2271746
15149198	15149221	11	-	24336569	HL60	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.23645888945096316	[1009]	[2517]	2	hSpCas9	negative selection	2271747
15149209	15149232	11	-	24336569	HL60	viability	CCGCTGACCCGGCAGGGTGACGG	INSC	ENSG00000188487	-0.12290337447556893	[723]	[1406]	-1	hSpCas9	negative selection	2271748
15149215	15149238	11	-	24336569	HL60	viability	GACTTACCGCTGACCCGGCAGGG	INSC	ENSG00000188487	-0.2765359159658325	[1189]	[2078]	-2	hSpCas9	negative selection	2271749
15149220	15149243	11	-	24336569	HL60	viability	TGTAGGACTTACCGCTGACCCGG	INSC	ENSG00000188487	0.40024443829523526	[443]	[1239]	3	hSpCas9	negative selection	2271750
15175735	15175758	11	+	24336569	HL60	viability	TTGCAGGCTACACCTGATGCAGG	INSC	ENSG00000188487	0.2922897172484878	[513]	[1331]	2	hSpCas9	negative selection	2271751
15175747	15175770	11	-	24336569	HL60	viability	GGACTGAGTCCACCTGCATCAGG	INSC	ENSG00000188487	0.24496538649340682	[767]	[1925]	2	hSpCas9	negative selection	2271752
15175755	15175778	11	+	24336569	HL60	viability	AGGTGGACTCAGTCCAGCGCTGG	INSC	ENSG00000188487	0.2011748631444088	[803]	[1955]	2	hSpCas9	negative selection	2271753
15175768	15175791	11	-	24336569	HL60	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	0.4582811266758372	[766]	[2229]	4	hSpCas9	negative selection	2271754
15149169	15149192	11	+	24336569	KBM7	viability	ATCAACATGATGGCACTGCCTGG	INSC	ENSG00000188487	0.6512684965212359	[838]	[3593]	6	hSpCas9	negative selection	2338922
15149183	15149206	11	+	24336569	KBM7	viability	ACTGCCTGGAGGTCGCCACCTGG	INSC	ENSG00000188487	1.0201789825283527	[266]	[1476]	8	hSpCas9	negative selection	2338923
15149198	15149221	11	-	24336569	KBM7	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	-1.0534847570906318	[849]	[1116]	-6	hSpCas9	negative selection	2338924
15149209	15149232	11	-	24336569	KBM7	viability	CCGCTGACCCGGCAGGGTGACGG	INSC	ENSG00000188487	1.2377278333283068	[316]	[2038]	8	hSpCas9	negative selection	2338925
15149215	15149238	11	-	24336569	KBM7	viability	GACTTACCGCTGACCCGGCAGGG	INSC	ENSG00000188487	0.39892677235418617	[752]	[2707]	3	hSpCas9	negative selection	2338926
15149220	15149243	11	-	24336569	KBM7	viability	TGTAGGACTTACCGCTGACCCGG	INSC	ENSG00000188487	0.691439763307715	[345]	[1523]	6	hSpCas9	negative selection	2338927
15175735	15175758	11	+	24336569	KBM7	viability	TTGCAGGCTACACCTGATGCAGG	INSC	ENSG00000188487	0.07390924436060389	[332]	[955]	0	hSpCas9	negative selection	2338928
15175747	15175770	11	-	24336569	KBM7	viability	GGACTGAGTCCACCTGCATCAGG	INSC	ENSG00000188487	0.33167435495822917	[510]	[1753]	3	hSpCas9	negative selection	2338929
15175755	15175778	11	+	24336569	KBM7	viability	AGGTGGACTCAGTCCAGCGCTGG	INSC	ENSG00000188487	0.08952222839991397	[663]	[1926]	0	hSpCas9	negative selection	2338930
15175768	15175791	11	-	24336569	KBM7	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	-0.33857665919727475	[961]	[2074]	-3	hSpCas9	negative selection	2338931
15225515	15225538	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTTTCCTCATCTGTAAAATGG	INSC	ENSG00000188487	0.07375301579419674	[56,81]	[7,23]	0	dCas9-VP64	positive selection	2386810
15212169	15212192	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCGGAGGTTGCAGTGAGCTAG	INSC	ENSG00000188487	-1.3881494200540772	[95,289]	[14,16]	-7	dCas9-VP64	positive selection	2387257
15114745	15114768	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACGGCTGCCTGCTGTCTCCGCGG	INSC	ENSG00000188487	-0.170822955573518	[80,10]	[12,3]	0	dCas9-VP64	positive selection	2392587
15114774	15114797	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGGGACCAAGGCTTGGCAGGG	INSC	ENSG00000188487	-0.3895402616205948	[55,232]	[15,32]	-2	dCas9-VP64	positive selection	2392588
15114825	15114848	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCTGCGACCGCCTCGGAGAGGG	INSC	ENSG00000188487	2.48325164460417	[83,1]	[96,2]	8	dCas9-VP64	positive selection	2392589
15180011	15180034	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTTGGGAGGCCAAGGCGGGCAG	INSC	ENSG00000188487	0.09588317305989913	[114,12]	[10,18]	0	dCas9-VP64	positive selection	2411109
15148991	15149014	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTGGTTCAACAGAAGAAGAGGG	INSC	ENSG00000188487	-1.6956108757069621	[420,30]	[22,4]	-8	dCas9-VP64	positive selection	2419901
15148961	15148984	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCAGTATCCTCACACAAGTAAGG	INSC	ENSG00000188487	-0.4893417110088474	[230,131]	[39,14]	-2	dCas9-VP64	positive selection	2419902
15148908	15148931	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TAGAGATATAAAGTGGGCTAGGG	INSC	ENSG00000188487	1.802316616792306	[84,31]	[24,64]	6	dCas9-VP64	positive selection	2419903
15225515	15225538	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTTTCCTCATCTGTAAAATGG	INSC	ENSG00000188487	-0.8821779957181084	[358,162]	[56,35]	-8	dCas9-VP64	positive selection	2482065
15212169	15212192	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCGGAGGTTGCAGTGAGCTAG	INSC	ENSG00000188487	-0.15452703381003985	[117,34]	[33,11]	-1	dCas9-VP64	positive selection	2482512
15114745	15114768	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACGGCTGCCTGCTGTCTCCGCGG	INSC	ENSG00000188487	-1.3624989558830256	[332,74]	[33,17]	-9	dCas9-VP64	positive selection	2487842
15114774	15114797	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGGGACCAAGGCTTGGCAGGG	INSC	ENSG00000188487	0.40543014345495354	[202,98]	[41,86]	3	dCas9-VP64	positive selection	2487843
15114825	15114848	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCTGCGACCGCCTCGGAGAGGG	INSC	ENSG00000188487	-0.014161801757819559	[77,51]	[18,21]	0	dCas9-VP64	positive selection	2487844
15180011	15180034	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTTGGGAGGCCAAGGCGGGCAG	INSC	ENSG00000188487	3.077269363618506	[19,18]	[13,93]	9	dCas9-VP64	positive selection	2506364
15148991	15149014	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTGGTTCAACAGAAGAAGAGGG	INSC	ENSG00000188487	1.8477121745646696	[229,273]	[166,416]	8	dCas9-VP64	positive selection	2515156
15148961	15148984	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCAGTATCCTCACACAAGTAAGG	INSC	ENSG00000188487	-0.41810410784364316	[212,361]	[78,59]	-4	dCas9-VP64	positive selection	2515157
15148908	15148931	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TAGAGATATAAAGTGGGCTAGGG	INSC	ENSG00000188487	-0.946663403407766	[151,124]	[20,24]	-8	dCas9-VP64	positive selection	2515158
15190739	15190762	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACACCACAGAGTCCACCACAGGG	INSC	ENSG00000188487	0.5577291127660414	[2,3]	[3,4]	9	hSpCas9	positive selection	2995688
15175905	15175928	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGCAGCTGCTGCTCAAACGGGG	INSC	ENSG00000188487	-0.5958121016822312	[3,3]	[1,1]	-7	hSpCas9	positive selection	2995689
15149198	15149221	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.22546301531234092	[4,4]	[4,4]	5	hSpCas9	positive selection	2995690
15175978	15176001	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGCTGTGCACCCGTGCCCAGCGG	INSC	ENSG00000188487	-0.2910892589586611	[3,3]	[2,1]	-4	hSpCas9	positive selection	2995691
15190739	15190762	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACACCACAGAGTCCACCACAGGG	INSC	ENSG00000188487	0.42718791622844376	[2,2]	[2,2]	7	hSpCas9	positive selection	3063546
15175905	15175928	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGCAGCTGCTGCTCAAACGGGG	INSC	ENSG00000188487	0.3806075853635081	[3,3]	[2,3]	6	hSpCas9	positive selection	3063547
15149198	15149221	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	-0.8226480541621849	[4,4]	[2,0]	-9	hSpCas9	positive selection	3063548
15175978	15176001	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGCTGTGCACCCGTGCCCAGCGG	INSC	ENSG00000188487	-0.1846859437658282	[3,3]	[3,0]	-3	hSpCas9	positive selection	3063549
15176040	15176063		+	24336571	A375	resistance to PLX after 7 days	GCGAGTACAGTGCTGTCAGCAGG	INSC	ENSG00000188487	-0.029562882888103603	[30,31]	[29,29]	-1	hSpCas9	positive selection	3121291
15149129	15149152		+	24336571	A375	resistance to PLX after 7 days	GGGTCACGACCGCTGCAAGCAGG	INSC	ENSG00000188487	0.25486862510368136	[8,7]	[11,8]	7	hSpCas9	positive selection	3121292
15175932	15175955		+	24336571	A375	resistance to PLX after 7 days	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.12342184059457395	[23,25]	[23,29]	4	hSpCas9	positive selection	3121293
15149220	15149243		-	24336571	A375	resistance to PLX after 7 days	TGTAGGACTTACCGCTGACCCGG	INSC	ENSG00000188487	0.23216282454084602	[25,30]	[33,32]	6	hSpCas9	positive selection	3121294
15176040	15176063		+	24336571	A375	resistance to PLX after 14 days	GCGAGTACAGTGCTGTCAGCAGG	INSC	ENSG00000188487	1.039903022296469	[34,32]	[30,34]	8	hSpCas9	positive selection	3179084
15149129	15149152		+	24336571	A375	resistance to PLX after 14 days	GGGTCACGACCGCTGCAAGCAGG	INSC	ENSG00000188487	-0.7437194910631917	[10,14]	[2,3]	-8	hSpCas9	positive selection	3179085
15175932	15175955		+	24336571	A375	resistance to PLX after 14 days	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.20529135677990984	[20,26]	[12,11]	2	hSpCas9	positive selection	3179086
15149220	15149243		-	24336571	A375	resistance to PLX after 14 days	TGTAGGACTTACCGCTGACCCGG	INSC	ENSG00000188487	0.05088561853022511	[33,39]	[16,17]	0	hSpCas9	positive selection	3179087
15176040	15176063		+	24336571	A375	viability after 7 days	GCGAGTACAGTGCTGTCAGCAGG	INSC	ENSG00000188487	0.053850968921799636	[31]	[30,31]	0	hSpCas9	negative selection	3236877
15149129	15149152		+	24336571	A375	viability after 7 days	GGGTCACGACCGCTGCAAGCAGG	INSC	ENSG00000188487	-0.09618110638545052	[9]	[8,7]	-1	hSpCas9	negative selection	3236878
15175932	15175955		+	24336571	A375	viability after 7 days	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.331582706588055	[32]	[23,25]	-5	hSpCas9	negative selection	3236879
15149220	15149243		-	24336571	A375	viability after 7 days	TGTAGGACTTACCGCTGACCCGG	INSC	ENSG00000188487	0.09920978338747521	[27]	[25,30]	1	hSpCas9	negative selection	3236880
15176040	15176063		+	24336571	A375	viability after 14 days	GCGAGTACAGTGCTGTCAGCAGG	INSC	ENSG00000188487	0.19800987358711652	[31]	[34,32]	2	hSpCas9	negative selection	3294670
15149129	15149152		+	24336571	A375	viability after 14 days	GGGTCACGACCGCTGCAAGCAGG	INSC	ENSG00000188487	0.5023261125135845	[9]	[10,14]	6	hSpCas9	negative selection	3294671
15175932	15175955		+	24336571	A375	viability after 14 days	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.3887318437812698	[32]	[20,26]	-4	hSpCas9	negative selection	3294672
15149220	15149243		-	24336571	A375	viability after 14 days	TGTAGGACTTACCGCTGACCCGG	INSC	ENSG00000188487	0.481893736010065	[27]	[33,39]	6	hSpCas9	negative selection	3294673
15149187	15149210	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	1.7654731151161607	[44,44]	[0,0]	7	hSpCas9	positive selection	3374419
15177142	15177165	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	-0.6435405965349134	[238,238]	[0,0]	-4	hSpCas9	positive selection	3374420
15177107	15177130	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.15929412848530838	[136,136]	[0,0]	0	hSpCas9	positive selection	3374421
15190738	15190761	11	+	26780180	HT29	viability (Avana library 4 designs)	ACACCACAGAGTCCACCACAGGG	INSC	ENSG00000188487	1.27514715505767	[]	[]	5	hSpCas9	negative selection	3433069
15175904	15175927	11	+	26780180	HT29	viability (Avana library 4 designs)	CTGCAGCTGCTGCTCAAACGGGG	INSC	ENSG00000188487	1.35262715648255	[]	[]	5	hSpCas9	negative selection	3433070
15149198	15149221	11	-	26780180	HT29	viability (Avana library 4 designs)	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	1.06168267054564	[]	[]	4	hSpCas9	negative selection	3433071
15175978	15176001	11	-	26780180	HT29	viability (Avana library 4 designs)	TGCTGTGCACCCGTGCCCAGCGG	INSC	ENSG00000188487	1.2848707787855	[]	[]	5	hSpCas9	negative selection	3433072
15149198	15149221	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	3.20443198251003	[]	[]	5	hSpCas9	negative selection	3519506
15175904	15175927	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGCAGCTGCTGCTCAAACGGGG	INSC	ENSG00000188487	5.88634723598715	[]	[]	9	hSpCas9	negative selection	3519507
15190738	15190761	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACACCACAGAGTCCACCACAGGG	INSC	ENSG00000188487	2.43116172658832	[]	[]	3	hSpCas9	negative selection	3519508
15175978	15176001	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGCTGTGCACCCGTGCCCAGCGG	INSC	ENSG00000188487	4.96423901480628	[]	[]	8	hSpCas9	negative selection	3519509
15176025	15176048	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACTCGCTGACCATGGAGCGGG	INSC	ENSG00000188487	-2.29832962145709	[]	[]	-3	hSpCas9	negative selection	3519510
15190766	15190789	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCAGCCTGACCCAGGAGGGGG	INSC	ENSG00000188487	5.41222664129919	[]	[]	8	hSpCas9	negative selection	3519511
15149198	15149221	11	-	26780180	A375	viability (Avana lentiGuide)	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	1.56140400749315	[]	[]	1	hSpCas9	negative selection	3628165
15175904	15175927	11	+	26780180	A375	viability (Avana lentiGuide)	CTGCAGCTGCTGCTCAAACGGGG	INSC	ENSG00000188487	1.2302158839591	[]	[]	1	hSpCas9	negative selection	3628166
15190738	15190761	11	+	26780180	A375	viability (Avana lentiGuide)	ACACCACAGAGTCCACCACAGGG	INSC	ENSG00000188487	-3.2411800931625	[]	[]	-5	hSpCas9	negative selection	3628167
15175978	15176001	11	-	26780180	A375	viability (Avana lentiGuide)	TGCTGTGCACCCGTGCCCAGCGG	INSC	ENSG00000188487	0.699101117133561	[]	[]	0	hSpCas9	negative selection	3628168
15176025	15176048	11	-	26780180	A375	viability (Avana lentiGuide)	GTACTCGCTGACCATGGAGCGGG	INSC	ENSG00000188487	4.28647685602619	[]	[]	4	hSpCas9	negative selection	3628169
15190766	15190789	11	+	26780180	A375	viability (Avana lentiGuide)	GTTCAGCCTGACCCAGGAGGGGG	INSC	ENSG00000188487	2.24323798137017	[]	[]	2	hSpCas9	negative selection	3628170
15149198	15149221	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.1234143463887484	[5]	[6,4]	3	hSpCas9	positive selection	3736824
15175904	15175927	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGCAGCTGCTGCTCAAACGGGG	INSC	ENSG00000188487	0.24355094372760325	[4]	[5,4]	7	hSpCas9	positive selection	3736825
15190738	15190761	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACACCACAGAGTCCACCACAGGG	INSC	ENSG00000188487	0.12180009565129218	[4]	[5,4]	3	hSpCas9	positive selection	3736826
15175978	15176001	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCTGTGCACCCGTGCCCAGCGG	INSC	ENSG00000188487	0.23789124282492602	[4]	[5,5]	6	hSpCas9	positive selection	3736827
15176025	15176048	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACTCGCTGACCATGGAGCGGG	INSC	ENSG00000188487	0.15665162880814953	[5]	[6,5]	4	hSpCas9	positive selection	3736828
15190766	15190789	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCAGCCTGACCCAGGAGGGGG	INSC	ENSG00000188487	0.22998370022298437	[5]	[6,6]	6	hSpCas9	positive selection	3736829
15149198	15149221	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	-0.0410040464131394	[6]	[5,5]	0	hSpCas9	positive selection	3845431
15175904	15175927	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGCAGCTGCTGCTCAAACGGGG	INSC	ENSG00000188487	-0.5082010385594744	[5]	[1,4]	-6	hSpCas9	positive selection	3845432
15190738	15190761	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACACCACAGAGTCCACCACAGGG	INSC	ENSG00000188487	-0.33950163194757155	[4]	[0,5]	-4	hSpCas9	positive selection	3845433
15175978	15176001	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCTGTGCACCCGTGCCCAGCGG	INSC	ENSG00000188487	0.040486088750317346	[5]	[4,4]	0	hSpCas9	positive selection	3845434
15176025	15176048	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACTCGCTGACCATGGAGCGGG	INSC	ENSG00000188487	0.14736555912382837	[6]	[6,6]	3	hSpCas9	positive selection	3845435
15190766	15190789	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCAGCCTGACCCAGGAGGGGG	INSC	ENSG00000188487	0.0013996238587591636	[6]	[4,5]	0	hSpCas9	positive selection	3845436
15177107	15177130	11	+	26780180	A375	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.699738653907245	[]	[]	2	hSpCas9	negative selection	3951435
15176031	15176054	11	-	26780180	A375	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.758792300394446	[]	[]	3	hSpCas9	negative selection	3951436
15177142	15177165	11	+	26780180	A375	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.304398661070279	[]	[]	0	hSpCas9	negative selection	3951437
15149187	15149210	11	-	26780180	A375	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.880775376693004	[]	[]	3	hSpCas9	negative selection	3951438
15149216	15149239	11	-	26780180	A375	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.872254451113379	[]	[]	3	hSpCas9	negative selection	3951439
15175932	15175955	11	+	26780180	A375	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.693413772671473	[]	[]	2	hSpCas9	negative selection	3951440
15177107	15177130	11	+	26780180	HT29	viability (GeCKOv2 library)	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	1.53317777482366	[]	[]	7	hSpCas9	negative selection	4059401
15176031	15176054	11	-	26780180	HT29	viability (GeCKOv2 library)	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.867028100964577	[]	[]	3	hSpCas9	negative selection	4059402
15177142	15177165	11	+	26780180	HT29	viability (GeCKOv2 library)	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	1.13526235539524	[]	[]	5	hSpCas9	negative selection	4059403
15149187	15149210	11	-	26780180	HT29	viability (GeCKOv2 library)	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.555771609851469	[]	[]	1	hSpCas9	negative selection	4059404
15149216	15149239	11	-	26780180	HT29	viability (GeCKOv2 library)	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	1.02108287602485	[]	[]	4	hSpCas9	negative selection	4059405
15175932	15175955	11	+	26780180	HT29	viability (GeCKOv2 library)	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	1.25910723886768	[]	[]	6	hSpCas9	negative selection	4059406
15176040	15176063	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGAGTACAGTGCTGTCAGCAGG	INSC	ENSG00000188487	0.2771981180831673	[4]	[2,4]	7	hSpCas9	positive selection	4144970
15149129	15149152	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGTCACGACCGCTGCAAGCAGG	INSC	ENSG00000188487	-0.058995958813126165	[3]	[1,1]	-1	hSpCas9	positive selection	4144971
15175932	15175955	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.14126472802159495	[4]	[2,3]	3	hSpCas9	positive selection	4144972
15149220	15149243	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTAGGACTTACCGCTGACCCGG	INSC	ENSG00000188487	0.3286442718450452	[4]	[3,4]	7	hSpCas9	positive selection	4144973
15176040	15176063	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGAGTACAGTGCTGTCAGCAGG	INSC	ENSG00000188487	0.8187621277678606	[5]	[3,3,1,5]	5	hSpCas9	positive selection	4208992
15149129	15149152	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGTCACGACCGCTGCAAGCAGG	INSC	ENSG00000188487	0.10091667267049662	[2]	[0,0,4,0]	0	hSpCas9	positive selection	4208993
15175932	15175955	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.0602829560222444	[4]	[2,3,0,0]	-1	hSpCas9	positive selection	4208994
15149220	15149243	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTAGGACTTACCGCTGACCCGG	INSC	ENSG00000188487	0.3600428017774647	[3]	[1,4,4,0]	2	hSpCas9	positive selection	4208995
15149216	15149239	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.2684311510279635	[1]	[2,1]	5	hSpCas9	positive selection	4277052
15175932	15175955	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.07474015209975693	[1]	[1,1]	1	hSpCas9	positive selection	4277053
15176031	15176054	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.0880730174332288	[3]	[3,1]	-2	hSpCas9	positive selection	4277054
15136617	15136640	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-0.47949429844642655	[1]	[1,0]	-8	hSpCas9	positive selection	4311043
15149187	15149210	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.3558497736837542	[1]	[1,1]	7	hSpCas9	positive selection	4341309
15177142	15177165	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.1826484417346361	[3]	[3,2]	3	hSpCas9	positive selection	4341310
15177107	15177130	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.34684661327200783	[2]	[2,2]	7	hSpCas9	positive selection	4341311
15175933	15175955	11	+	27760321	OCIAML3	viability	CATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.1963654679132899	[653,577]	[318,550]	-2	hSpCas9	negative selection	4409921
15176031	15176053	11	-	27760321	OCIAML3	viability	GCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.5905396003540333	[1173,891]	[978,1503]	7	hSpCas9	negative selection	4409922
15178421	15178443	11	+	27760321	OCIAML3	viability	GAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.3715512446085313	[888,767]	[710,998]	4	hSpCas9	negative selection	4409923
15190791	15190813	11	-	27760321	OCIAML3	viability	TGGCTATGATGCGGCACAAGGG	INSC	ENSG00000188487	-0.2895667988374046	[673,548]	[344,446]	-3	hSpCas9	negative selection	4409924
15221506	15221528	11	-	27760321	OCIAML3	viability	TGAGTGGCTGTTGTCGGTCAGG	INSC	ENSG00000188487	0.31602812681374925	[863,899]	[773,978]	3	hSpCas9	negative selection	4409925
15175933	15175955	11	+	27760321	OCIAML2	viability	CATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.15950207201180855	[653,577]	[407,749]	2	hSpCas9	negative selection	4493384
15176031	15176053	11	-	27760321	OCIAML2	viability	GCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.5930037464929674	[1173,891]	[1196,1320]	7	hSpCas9	negative selection	4493385
15178421	15178443	11	+	27760321	OCIAML2	viability	GAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.13803029115566112	[888,767]	[659,834]	1	hSpCas9	negative selection	4493386
15190791	15190813	11	-	27760321	OCIAML2	viability	TGGCTATGATGCGGCACAAGGG	INSC	ENSG00000188487	0.13721279109978346	[673,548]	[419,700]	1	hSpCas9	negative selection	4493387
15221506	15221528	11	-	27760321	OCIAML2	viability	TGAGTGGCTGTTGTCGGTCAGG	INSC	ENSG00000188487	0.5367498738827363	[863,899]	[987,1108]	7	hSpCas9	negative selection	4493388
15175933	15175955	11	+	27760321	MV411	viability	CATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.046176843735755146	[653,577]	[143,766]	0	hSpCas9	negative selection	4576847
15176031	15176053	11	-	27760321	MV411	viability	GCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.8986721076387159	[1173,891]	[1283,1225]	6	hSpCas9	negative selection	4576848
15178421	15178443	11	+	27760321	MV411	viability	GAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	-0.388387335269614	[888,767]	[366,490]	-3	hSpCas9	negative selection	4576849
15190791	15190813	11	-	27760321	MV411	viability	TGGCTATGATGCGGCACAAGGG	INSC	ENSG00000188487	0.4461208001810627	[673,548]	[727,274]	3	hSpCas9	negative selection	4576850
15221506	15221528	11	-	27760321	MV411	viability	TGAGTGGCTGTTGTCGGTCAGG	INSC	ENSG00000188487	-0.5277064446996971	[863,899]	[324,526]	-4	hSpCas9	negative selection	4576851
15175933	15175955	11	+	27760321	HL60	viability	CATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.6053727277453659	[653,577]	[434,218]	-6	hSpCas9	negative selection	4660310
15176031	15176053	11	-	27760321	HL60	viability	GCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.03247574462676073	[1173,891]	[713,1006]	0	hSpCas9	negative selection	4660311
15178421	15178443	11	+	27760321	HL60	viability	GAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.33714495876514194	[888,767]	[740,970]	4	hSpCas9	negative selection	4660312
15190791	15190813	11	-	27760321	HL60	viability	TGGCTATGATGCGGCACAAGGG	INSC	ENSG00000188487	-0.09034406521172589	[673,548]	[509,420]	-1	hSpCas9	negative selection	4660313
15221506	15221528	11	-	27760321	HL60	viability	TGAGTGGCTGTTGTCGGTCAGG	INSC	ENSG00000188487	0.07475277884028686	[863,899]	[714,812]	0	hSpCas9	negative selection	4660314
15175933	15175955	11	+	27760321	HT1080	viability	CATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.7877120762296714	[577,450]	[133,101]	-3	hSpCas9	negative selection	4743773
15176031	15176053	11	-	27760321	HT1080	viability	GCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	1.3645316797078926	[891,695]	[412,1253]	7	hSpCas9	negative selection	4743774
15178421	15178443	11	+	27760321	HT1080	viability	GAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	-2.9503330106437513	[767,598]	[39,29]	-7	hSpCas9	negative selection	4743775
15190791	15190813	11	-	27760321	HT1080	viability	TGGCTATGATGCGGCACAAGGG	INSC	ENSG00000188487	-0.4997187933984591	[548,428]	[206,61]	-2	hSpCas9	negative selection	4743776
15221506	15221528	11	-	27760321	HT1080	viability	TGAGTGGCTGTTGTCGGTCAGG	INSC	ENSG00000188487	0.7873536388881932	[899,701]	[396,718]	4	hSpCas9	negative selection	4743777
15175933	15175955	11	+	27760321	HT29	viability after 7 days	CATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.5204848490225817	[577,450]	[800,256,375]	-6	hSpCas9	negative selection	4827236
15176031	15176053	11	-	27760321	HT29	viability after 7 days	GCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.45356219075275095	[891,695]	[1482,1196,1519]	7	hSpCas9	negative selection	4827237
15178421	15178443	11	+	27760321	HT29	viability after 7 days	GAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.5196432077307735	[767,598]	[1533,1289,1000]	7	hSpCas9	negative selection	4827238
15190791	15190813	11	-	27760321	HT29	viability after 7 days	TGGCTATGATGCGGCACAAGGG	INSC	ENSG00000188487	0.09850857832901144	[548,428]	[607,622,774]	1	hSpCas9	negative selection	4827239
15221506	15221528	11	-	27760321	HT29	viability after 7 days	TGAGTGGCTGTTGTCGGTCAGG	INSC	ENSG00000188487	-0.28426951206705564	[899,701]	[1047,557,954]	-4	hSpCas9	negative selection	4827240
15175933	15175955	11	+	27760321	HT29	viability after 25 days	CATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.18861395395513908	[577,450]	[439,541,575]	-2	hSpCas9	negative selection	4910699
15176031	15176053	11	-	27760321	HT29	viability after 25 days	GCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.8916601139138067	[891,695]	[1540,1615,1924]	9	hSpCas9	negative selection	4910700
15178421	15178443	11	+	27760321	HT29	viability after 25 days	GAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.13640962213509278	[767,598]	[810,677,1114]	1	hSpCas9	negative selection	4910701
15190791	15190813	11	-	27760321	HT29	viability after 25 days	TGGCTATGATGCGGCACAAGGG	INSC	ENSG00000188487	0.22001028661426164	[548,428]	[602,656,699]	2	hSpCas9	negative selection	4910702
15221506	15221528	11	-	27760321	HT29	viability after 25 days	TGAGTGGCTGTTGTCGGTCAGG	INSC	ENSG00000188487	-0.07031721190638485	[899,701]	[712,807,1129]	0	hSpCas9	negative selection	4910703
15175933	15175955	11	+	27760321	HT29	viability after 22 days	CATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.0035088495948770726	[577,450]	[772,525,474]	0	hSpCas9	negative selection	4994162
15176031	15176053	11	-	27760321	HT29	viability after 22 days	GCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.8759574523296143	[891,695]	[1917,1676,1449]	8	hSpCas9	negative selection	4994163
15178421	15178443	11	+	27760321	HT29	viability after 22 days	GAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	-0.1898497806390641	[767,598]	[700,668,707]	-2	hSpCas9	negative selection	4994164
15190791	15190813	11	-	27760321	HT29	viability after 22 days	TGGCTATGATGCGGCACAAGGG	INSC	ENSG00000188487	0.11340719097592572	[548,428]	[497,602,737]	1	hSpCas9	negative selection	4994165
15221506	15221528	11	-	27760321	HT29	viability after 22 days	TGAGTGGCTGTTGTCGGTCAGG	INSC	ENSG00000188487	0.35626335945343524	[899,701]	[1260,782,1512]	4	hSpCas9	negative selection	4994166
15175933	15175955	11	+	27760321	HT29	viability after 19 days	CATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.0706076942186794	[577,450]	[576,965,154]	0	hSpCas9	negative selection	5077625
15176031	15176053	11	-	27760321	HT29	viability after 19 days	GCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.9843326159987225	[891,695]	[1909,1875,1620]	8	hSpCas9	negative selection	5077626
15178421	15178443	11	+	27760321	HT29	viability after 19 days	GAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.41857530111897545	[767,598]	[918,580,1598]	4	hSpCas9	negative selection	5077627
15190791	15190813	11	-	27760321	HT29	viability after 19 days	TGGCTATGATGCGGCACAAGGG	INSC	ENSG00000188487	-0.05954235442356315	[548,428]	[750,206,668]	0	hSpCas9	negative selection	5077628
15221506	15221528	11	-	27760321	HT29	viability after 19 days	TGAGTGGCTGTTGTCGGTCAGG	INSC	ENSG00000188487	-0.010465719216157465	[899,701]	[1131,763,856]	0	hSpCas9	negative selection	5077629
15175933	15175955	11	+	27760321	HT29	viability after 16 days	CATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.06482312964900894	[577,450]	[554,550,696]	0	hSpCas9	negative selection	5161088
15176031	15176053	11	-	27760321	HT29	viability after 16 days	GCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.9389429976809924	[891,695]	[2237,1484,1441]	9	hSpCas9	negative selection	5161089
15178421	15178443	11	+	27760321	HT29	viability after 16 days	GAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.35902501926784547	[767,598]	[909,1262,754]	4	hSpCas9	negative selection	5161090
15190791	15190813	11	-	27760321	HT29	viability after 16 days	TGGCTATGATGCGGCACAAGGG	INSC	ENSG00000188487	0.19966276730540528	[548,428]	[700,620,569]	2	hSpCas9	negative selection	5161091
15221506	15221528	11	-	27760321	HT29	viability after 16 days	TGAGTGGCTGTTGTCGGTCAGG	INSC	ENSG00000188487	0.07025977415072182	[899,701]	[1041,900,889]	0	hSpCas9	negative selection	5161092
15175933	15175955	11	+	27760321	HT29	viability after 13 days	CATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.28833868598912776	[577,450]	[643,302,516]	-4	hSpCas9	negative selection	5244551
15176031	15176053	11	-	27760321	HT29	viability after 13 days	GCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.707821939915112	[891,695]	[1775,1580,1175]	8	hSpCas9	negative selection	5244552
15178421	15178443	11	+	27760321	HT29	viability after 13 days	GAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.31942522059620004	[767,598]	[891,911,1153]	4	hSpCas9	negative selection	5244553
15190791	15190813	11	-	27760321	HT29	viability after 13 days	TGGCTATGATGCGGCACAAGGG	INSC	ENSG00000188487	0.015505248227658752	[548,428]	[630,461,623]	0	hSpCas9	negative selection	5244554
15221506	15221528	11	-	27760321	HT29	viability after 13 days	TGAGTGGCTGTTGTCGGTCAGG	INSC	ENSG00000188487	-0.1928795307286354	[899,701]	[947,620,865]	-2	hSpCas9	negative selection	5244555
15175933	15175955	11	+	27760321	HT29	viability after 10 days	CATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.5147771052113308	[577,450]	[457,671,229]	-6	hSpCas9	negative selection	5328014
15176031	15176053	11	-	27760321	HT29	viability after 10 days	GCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.41238820068460935	[891,695]	[1287,1215,1447]	5	hSpCas9	negative selection	5328015
15178421	15178443	11	+	27760321	HT29	viability after 10 days	GAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	-0.020830041166793545	[767,598]	[940,791,789]	0	hSpCas9	negative selection	5328016
15190791	15190813	11	-	27760321	HT29	viability after 10 days	TGGCTATGATGCGGCACAAGGG	INSC	ENSG00000188487	0.034635682354099584	[548,428]	[661,344,855]	0	hSpCas9	negative selection	5328017
15221506	15221528	11	-	27760321	HT29	viability after 10 days	TGAGTGGCTGTTGTCGGTCAGG	INSC	ENSG00000188487	-0.2027684101162599	[899,701]	[1221,697,685]	-3	hSpCas9	negative selection	5328018
15175933	15175955	11	+	27760321	MOLM13	viability	CATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.5313371226036195	[653,577]	[299,188]	-3	hSpCas9	negative selection	5411477
15176031	15176053	11	-	27760321	MOLM13	viability	GCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.3506502663674087	[1173,891]	[1210,333]	2	hSpCas9	negative selection	5411478
15178421	15178443	11	+	27760321	MOLM13	viability	GAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.017874552958871193	[888,767]	[135,757]	0	hSpCas9	negative selection	5411479
15190791	15190813	11	-	27760321	MOLM13	viability	TGGCTATGATGCGGCACAAGGG	INSC	ENSG00000188487	-0.11358900401243538	[673,548]	[333,302]	0	hSpCas9	negative selection	5411480
15221506	15221528	11	-	27760321	MOLM13	viability	TGAGTGGCTGTTGTCGGTCAGG	INSC	ENSG00000188487	-0.24016038473325918	[863,899]	[491,364]	-2	hSpCas9	negative selection	5411481
15115133	15115156	11	+	27661255	K562	viability	GGGAGCTTGCGCCAGTGTGAGGG	INSC	ENSG00000188487	0.10726977946226621	[771,968]	[813,687]	4	dCas9-KRAB	negative selection	5486984
15114961	15114984	11	-	27661255	K562	viability	GTAGTGCGAGCGGCCAGTGGTGG	INSC	ENSG00000188487	0.03143856296826303	[882,1095]	[835,777]	1	dCas9-KRAB	negative selection	5486985
15115048	15115071	11	-	27661255	K562	viability	GTTCCCAACTAGGCTAGCAGAGG	INSC	ENSG00000188487	0.01836364392027745	[313,378]	[253,300]	0	dCas9-KRAB	negative selection	5486986
15149216	15149239	11	-	27260156	BXPC3	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.4335943628906904	[187]	[235,291,265,267]	8	hSpCas9	negative selection	5549512
15175932	15175955	11	+	27260156	BXPC3	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.15384902893438013	[133]	[168,131,83,109]	-4	hSpCas9	negative selection	5549513
15176031	15176054	11	-	27260156	BXPC3	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.06563494350967806	[507]	[491,470,562,726]	1	hSpCas9	negative selection	5549514
15136617	15136640	11	-	27260156	BXPC3	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.8067564286912319	[184]	[30,93,63,28]	-9	hSpCas9	negative selection	5583503
15149187	15149210	11	-	27260156	BXPC3	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	-0.011357337632121656	[111]	[64,167,87,148]	0	hSpCas9	negative selection	5613769
15177142	15177165	11	+	27260156	BXPC3	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.007671563595170294	[568]	[500,599,507,814]	0	hSpCas9	negative selection	5613770
15177107	15177130	11	+	27260156	BXPC3	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.1390707593019768	[445]	[458,335,458,440]	-3	hSpCas9	negative selection	5613771
15149216	15149239	11	-	27260156	A673	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.29568516385983457	[187]	[365,285,212,251]	7	hSpCas9	negative selection	5670763
15175932	15175955	11	+	27260156	A673	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.11994076165691592	[133]	[206,148,141,97]	-3	hSpCas9	negative selection	5670764
15176031	15176054	11	-	27260156	A673	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.015304674139924354	[507]	[739,484,671,582]	0	hSpCas9	negative selection	5670765
15136617	15136640	11	-	27260156	A673	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.034389452720533	[184]	[174,78,127,56]	-9	hSpCas9	negative selection	5704754
15149187	15149210	11	-	27260156	A673	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.253487945629435	[111]	[159,171,143,164]	6	hSpCas9	negative selection	5735020
15177142	15177165	11	+	27260156	A673	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.23537071739188742	[568]	[785,818,818,787]	5	hSpCas9	negative selection	5735021
15177107	15177130	11	+	27260156	A673	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.2938917247499917	[445]	[780,576,604,679]	7	hSpCas9	negative selection	5735022
15149216	15149239	11	-	27260156	A375	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.48605159125139197	[187]	[367,212,398,243]	7	hSpCas9	negative selection	5792014
15175932	15175955	11	+	27260156	A375	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.3093010741735607	[133]	[81,190,137,104]	-4	hSpCas9	negative selection	5792015
15176031	15176054	11	-	27260156	A375	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.254007901260501	[507]	[445,506,388,630]	-4	hSpCas9	negative selection	5792016
15136617	15136640	11	-	27260156	A375	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-2.28053213134409	[184]	[101,8,61,4]	-9	hSpCas9	negative selection	5826005
15149187	15149210	11	-	27260156	A375	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.7177581024463087	[111]	[258,211,250,145]	9	hSpCas9	negative selection	5856271
15177142	15177165	11	+	27260156	A375	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.14038294448390115	[568]	[644,757,599,905]	2	hSpCas9	negative selection	5856272
15177107	15177130	11	+	27260156	A375	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.37240383429297946	[445]	[565,598,765,743]	5	hSpCas9	negative selection	5856273
15149216	15149239	11	-	27260156	COLO741	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.6357909723293989	[187]	[432,375,318]	9	hSpCas9	negative selection	5913265
15175932	15175955	11	+	27260156	COLO741	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.4809062113722842	[133]	[149,110,109]	-8	hSpCas9	negative selection	5913266
15176031	15176054	11	-	27260156	COLO741	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.126309359196989	[507]	[658,659,477]	-3	hSpCas9	negative selection	5913267
15136617	15136640	11	-	27260156	COLO741	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.8729860801199738	[184]	[103,59,34]	-9	hSpCas9	negative selection	5947256
15149187	15149210	11	-	27260156	COLO741	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.2543644297146246	[111]	[204,200,112]	5	hSpCas9	negative selection	5977522
15177142	15177165	11	+	27260156	COLO741	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.08420219702206588	[568]	[806,757,749]	1	hSpCas9	negative selection	5977523
15177107	15177130	11	+	27260156	COLO741	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.002582298874785366	[445]	[744,547,436]	0	hSpCas9	negative selection	5977524
15149216	15149239	11	-	27260156	CAL120	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.7652864539011485	[187]	[319,291,565]	9	hSpCas9	negative selection	6034516
15175932	15175955	11	+	27260156	CAL120	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.3130820244645802	[133]	[175,104,127]	-4	hSpCas9	negative selection	6034517
15176031	15176054	11	-	27260156	CAL120	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.07049245979719208	[507]	[538,415,836]	-1	hSpCas9	negative selection	6034518
15136617	15136640	11	-	27260156	CAL120	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.7573698186130406	[184]	[59,72,69]	-9	hSpCas9	negative selection	6068507
15149187	15149210	11	-	27260156	CAL120	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.3070094999057116	[111]	[176,174,165]	4	hSpCas9	negative selection	6098773
15177142	15177165	11	+	27260156	CAL120	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.48913909184378845	[568]	[1288,714,1020]	7	hSpCas9	negative selection	6098774
15177107	15177130	11	+	27260156	CAL120	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.275347578699761	[445]	[512,640,833]	4	hSpCas9	negative selection	6098775
15149216	15149239	11	-	27260156	CADOES1	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.39934536763351913	[187]	[244,190,263,221]	6	hSpCas9	negative selection	6155767
15175932	15175955	11	+	27260156	CADOES1	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.23463113902647592	[133]	[75,128,107,110]	-4	hSpCas9	negative selection	6155768
15176031	15176054	11	-	27260156	CADOES1	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.37399826624667976	[507]	[310,399,395,350]	-6	hSpCas9	negative selection	6155769
15136617	15136640	11	-	27260156	CADOES1	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.6707427160689483	[184]	[68,60,35,49]	-9	hSpCas9	negative selection	6189758
15149187	15149210	11	-	27260156	CADOES1	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.5893047070187372	[111]	[162,134,141,187]	8	hSpCas9	negative selection	6220024
15177142	15177165	11	+	27260156	CADOES1	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.163380232507844	[568]	[941,541,412,467]	3	hSpCas9	negative selection	6220025
15177107	15177130	11	+	27260156	CADOES1	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.11108401605754537	[445]	[435,503,222,372]	-2	hSpCas9	negative selection	6220026
15149216	15149239	11	-	27260156	EWS502	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	1.040834152621908	[187]	[277,391,289,713]	9	hSpCas9	negative selection	6277018
15175932	15175955	11	+	27260156	EWS502	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.19631663326492688	[133]	[63,207,287,96]	3	hSpCas9	negative selection	6277019
15176031	15176054	11	-	27260156	EWS502	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.41281667039518954	[507]	[310,416,400,503]	-6	hSpCas9	negative selection	6277020
15136617	15136640	11	-	27260156	EWS502	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-3.149566578715028	[184]	[8,13,20,47]	-9	hSpCas9	negative selection	6311009
15149187	15149210	11	-	27260156	EWS502	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	-0.31781296130390313	[111]	[146,65,95,63]	-5	hSpCas9	negative selection	6341275
15177142	15177165	11	+	27260156	EWS502	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.12964040660394582	[568]	[583,542,696,837]	2	hSpCas9	negative selection	6341276
15177107	15177130	11	+	27260156	EWS502	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.09359251620960324	[445]	[356,365,412,661]	-2	hSpCas9	negative selection	6341277
15149216	15149239	11	-	27260156	EW8	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.5517797414776643	[187]	[246,252,220,174]	8	hSpCas9	negative selection	6398269
15175932	15175955	11	+	27260156	EW8	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.2767893297473525	[133]	[150,90,42,87]	-5	hSpCas9	negative selection	6398270
15176031	15176054	11	-	27260156	EW8	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.3919180596605187	[507]	[307,302,327,311]	-6	hSpCas9	negative selection	6398271
15136617	15136640	11	-	27260156	EW8	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-2.405766482740793	[184]	[43,39,27,2]	-9	hSpCas9	negative selection	6432260
15149187	15149210	11	-	27260156	EW8	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.1781737873567042	[111]	[94,114,58,147]	3	hSpCas9	negative selection	6462526
15177142	15177165	11	+	27260156	EW8	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	-0.25818423931238055	[568]	[458,468,343,284]	-5	hSpCas9	negative selection	6462527
15177107	15177130	11	+	27260156	EW8	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.3375612182808306	[445]	[409,724,314,395]	6	hSpCas9	negative selection	6462528
15149216	15149239	11	-	27260156	CORL105	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.02310974981820535	[187]	[183,180,375,176]	0	hSpCas9	negative selection	6519520
15175932	15175955	11	+	27260156	CORL105	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.10233069748354229	[133]	[114,97,170,288]	2	hSpCas9	negative selection	6519521
15176031	15176054	11	-	27260156	CORL105	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.021933602557340934	[507]	[661,604,545,525]	0	hSpCas9	negative selection	6519522
15136617	15136640	11	-	27260156	CORL105	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-2.1351875878379287	[184]	[34,32,24,99]	-9	hSpCas9	negative selection	6553511
15149187	15149210	11	-	27260156	CORL105	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.6340059051164975	[111]	[141,212,163,285]	9	hSpCas9	negative selection	6583777
15177142	15177165	11	+	27260156	CORL105	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.055974669733218574	[568]	[592,550,879,773]	1	hSpCas9	negative selection	6583778
15177107	15177130	11	+	27260156	CORL105	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.10491544805450181	[445]	[347,722,691,492]	2	hSpCas9	negative selection	6583779
15149216	15149239	11	-	27260156	HS294T	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.4918406130615607	[187]	[65,136,84,126]	6	hSpCas9	negative selection	6640771
15175932	15175955	11	+	27260156	HS294T	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.5734430269454256	[133]	[36,164,54,46]	7	hSpCas9	negative selection	6640772
15176031	15176054	11	-	27260156	HS294T	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.2091193740299912	[507]	[186,164,196,391]	3	hSpCas9	negative selection	6640773
15136617	15136640	11	-	27260156	HS294T	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.7670951326813644	[184]	[1,30,23,29]	-9	hSpCas9	negative selection	6674762
15149187	15149210	11	-	27260156	HS294T	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	-0.02642837866967973	[111]	[79,18,35,29]	0	hSpCas9	negative selection	6705028
15177142	15177165	11	+	27260156	HS294T	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.01978918149122688	[568]	[306,185,175,213]	0	hSpCas9	negative selection	6705029
15177107	15177130	11	+	27260156	HS294T	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.1353251572635951	[445]	[101,152,170,216]	-2	hSpCas9	negative selection	6705030
15149216	15149239	11	-	27260156	HCC44	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.1353271948415915	[187]	[329,168,309,156]	2	hSpCas9	negative selection	6762022
15175932	15175955	11	+	27260156	HCC44	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.4041085282958181	[133]	[105,87,219,65]	-6	hSpCas9	negative selection	6762023
15176031	15176054	11	-	27260156	HCC44	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.1589461054715871	[507]	[828,497,402,820]	2	hSpCas9	negative selection	6762024
15136617	15136640	11	-	27260156	HCC44	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.1723248621432019	[184]	[23,29,353,12]	-9	hSpCas9	negative selection	6796013
15149187	15149210	11	-	27260156	HCC44	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.6265551391523272	[111]	[396,71,169,173]	8	hSpCas9	negative selection	6826279
15177142	15177165	11	+	27260156	HCC44	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.012560440231376646	[568]	[734,542,668,669]	0	hSpCas9	negative selection	6826280
15177107	15177130	11	+	27260156	HCC44	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.2514747598869706	[445]	[285,345,688,414]	-4	hSpCas9	negative selection	6826281
15149216	15149239	11	-	27260156	G402	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.7554097894809001	[187]	[294,366,271,588]	8	hSpCas9	negative selection	6883273
15175932	15175955	11	+	27260156	G402	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.4511788580872933	[133]	[64,180,73,151]	-5	hSpCas9	negative selection	6883274
15176031	15176054	11	-	27260156	G402	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.048935703492183846	[507]	[581,434,460,889]	0	hSpCas9	negative selection	6883275
15136617	15136640	11	-	27260156	G402	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.9923216925514087	[184]	[24,111,2,83]	-9	hSpCas9	negative selection	6917264
15149187	15149210	11	-	27260156	G402	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.5462113111770566	[111]	[104,333,160,191]	6	hSpCas9	negative selection	6947530
15177142	15177165	11	+	27260156	G402	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.11647016313080494	[568]	[1026,862,775,404]	1	hSpCas9	negative selection	6947531
15177107	15177130	11	+	27260156	G402	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.43629654585119176	[445]	[440,1346,908,261]	5	hSpCas9	negative selection	6947532
15149216	15149239	11	-	27260156	L33	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.2686105188043455	[187]	[267,80,168,170]	6	hSpCas9	negative selection	7004524
15175932	15175955	11	+	27260156	L33	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.34979937189568666	[133]	[214,79,64,167]	7	hSpCas9	negative selection	7004525
15176031	15176054	11	-	27260156	L33	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.3485076132394754	[507]	[345,138,360,338]	-7	hSpCas9	negative selection	7004526
15136617	15136640	11	-	27260156	L33	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.4380626385510125	[184]	[61,23,51,69]	-9	hSpCas9	negative selection	7038515
15149187	15149210	11	-	27260156	L33	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.22152373370739498	[111]	[83,59,78,166]	5	hSpCas9	negative selection	7068781
15177142	15177165	11	+	27260156	L33	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	-0.26677717555624786	[568]	[458,211,258,502]	-6	hSpCas9	negative selection	7068782
15177107	15177130	11	+	27260156	L33	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.004264444506150364	[445]	[469,196,263,417]	0	hSpCas9	negative selection	7068783
15149216	15149239	11	-	27260156	K562	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-0.16640827591534424	[187]	[258,139,105,102]	-2	hSpCas9	negative selection	7125775
15175932	15175955	11	+	27260156	K562	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.07902619144435952	[133]	[140,129,49,129]	-1	hSpCas9	negative selection	7125776
15176031	15176054	11	-	27260156	K562	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.13883830617859147	[507]	[599,196,551,303]	-2	hSpCas9	negative selection	7125777
15136617	15136640	11	-	27260156	K562	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-2.3365632556217983	[184]	[42,7,3,69]	-9	hSpCas9	negative selection	7159766
15149187	15149210	11	-	27260156	K562	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.9711884657574477	[111]	[60,258,425,42]	9	hSpCas9	negative selection	7190032
15177142	15177165	11	+	27260156	K562	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	-0.40106795319128347	[568]	[375,469,227,449]	-5	hSpCas9	negative selection	7190033
15177107	15177130	11	+	27260156	K562	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.3006038727924907	[445]	[1057,436,415,123]	4	hSpCas9	negative selection	7190034
15149216	15149239	11	-	27260156	HT29	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.39984602229486466	[187]	[468,301,199,251]	7	hSpCas9	negative selection	7247026
15175932	15175955	11	+	27260156	HT29	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.08174164183089183	[133]	[205,205,38,169]	-2	hSpCas9	negative selection	7247027
15176031	15176054	11	-	27260156	HT29	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.034794293880426014	[507]	[571,680,732,444]	0	hSpCas9	negative selection	7247028
15136617	15136640	11	-	27260156	HT29	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-3.913301628438184	[184]	[24,1,14,16]	-9	hSpCas9	negative selection	7281017
15149187	15149210	11	-	27260156	HT29	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.6047859211271249	[111]	[218,266,150,196]	9	hSpCas9	negative selection	7311283
15177142	15177165	11	+	27260156	HT29	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	-0.02407047453600014	[568]	[668,693,777,586]	0	hSpCas9	negative selection	7311284
15177107	15177130	11	+	27260156	HT29	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.2466198039688596	[445]	[613,792,547,625]	5	hSpCas9	negative selection	7311285
15149216	15149239	11	-	27260156	MHHES1	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.16902255942697342	[187]	[214,230,277,222]	3	hSpCas9	negative selection	7368277
15175932	15175955	11	+	27260156	MHHES1	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-1.0475866634770994	[133]	[92,56,102,44]	-9	hSpCas9	negative selection	7368278
15176031	15176054	11	-	27260156	MHHES1	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.07921141519658088	[507]	[717,640,597,490]	1	hSpCas9	negative selection	7368279
15136617	15136640	11	-	27260156	MHHES1	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-2.259563569805791	[184]	[0,56,85,28]	-9	hSpCas9	negative selection	7402268
15149187	15149210	11	-	27260156	MHHES1	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	-0.33444143371494084	[111]	[129,119,112,51]	-6	hSpCas9	negative selection	7432534
15177142	15177165	11	+	27260156	MHHES1	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	-0.16554006694776807	[568]	[536,693,518,537]	-3	hSpCas9	negative selection	7432535
15177107	15177130	11	+	27260156	MHHES1	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.28184186397388244	[445]	[425,423,384,410]	-5	hSpCas9	negative selection	7432536
15149216	15149239	11	-	27260156	MEWO	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.2138471650661471	[187]	[227,115,272]	5	hSpCas9	negative selection	7489528
15175932	15175955	11	+	27260156	MEWO	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.5359270103387934	[133]	[109,73,79]	-8	hSpCas9	negative selection	7489529
15176031	15176054	11	-	27260156	MEWO	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.1559195718595563	[507]	[539,347,413]	-3	hSpCas9	negative selection	7489530
15136617	15136640	11	-	27260156	MEWO	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.5173641708723737	[184]	[93,32,60]	-9	hSpCas9	negative selection	7523519
15149187	15149210	11	-	27260156	MEWO	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.33362982764803184	[111]	[223,115,73]	7	hSpCas9	negative selection	7553785
15177142	15177165	11	+	27260156	MEWO	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.00857670983809422	[568]	[653,609,364]	0	hSpCas9	negative selection	7553786
15177107	15177130	11	+	27260156	MEWO	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.17028982722378663	[445]	[449,303,373]	-4	hSpCas9	negative selection	7553787
15149216	15149239	11	-	27260156	LNCAPCLONEFGC	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.19322306815065038	[187]	[226,140,203,210]	3	hSpCas9	negative selection	7610779
15175932	15175955	11	+	27260156	LNCAPCLONEFGC	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.09583952347537239	[133]	[135,92,128,162]	1	hSpCas9	negative selection	7610780
15176031	15176054	11	-	27260156	LNCAPCLONEFGC	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.27092894200343004	[507]	[230,378,479,452]	-4	hSpCas9	negative selection	7610781
15136617	15136640	11	-	27260156	LNCAPCLONEFGC	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-2.0130034903862604	[184]	[27,52,57,28]	-9	hSpCas9	negative selection	7644770
15149187	15149210	11	-	27260156	LNCAPCLONEFGC	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.5351342403917458	[111]	[112,207,142,119]	8	hSpCas9	negative selection	7675036
15177142	15177165	11	+	27260156	LNCAPCLONEFGC	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.19007197564938033	[568]	[500,524,752,602]	3	hSpCas9	negative selection	7675037
15177107	15177130	11	+	27260156	LNCAPCLONEFGC	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.04765520139031712	[445]	[394,322,419,433]	0	hSpCas9	negative selection	7675038
15149216	15149239	11	-	27260156	PANC0327	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-0.2113139208959709	[187]	[98,154,215,101]	-3	hSpCas9	negative selection	7732030
15175932	15175955	11	+	27260156	PANC0327	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.5354226630252055	[133]	[62,33,46,188]	-6	hSpCas9	negative selection	7732031
15176031	15176054	11	-	27260156	PANC0327	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.06103618130230319	[507]	[366,560,575,358]	0	hSpCas9	negative selection	7732032
15136617	15136640	11	-	27260156	PANC0327	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-2.6607216555200024	[184]	[71,15,13,6]	-9	hSpCas9	negative selection	7766021
15149187	15149210	11	-	27260156	PANC0327	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.4830191946393927	[111]	[142,135,183,93]	7	hSpCas9	negative selection	7796287
15177142	15177165	11	+	27260156	PANC0327	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.36460394664747675	[568]	[979,511,683,471]	5	hSpCas9	negative selection	7796288
15177107	15177130	11	+	27260156	PANC0327	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.2733749252793561	[445]	[496,506,431,476]	4	hSpCas9	negative selection	7796289
15149216	15149239	11	-	27260156	NCIH2009	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.5073043717814645	[187]	[244,375,472]	7	hSpCas9	negative selection	7853281
15175932	15175955	11	+	27260156	NCIH2009	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.2512912100266993	[133]	[235,263,169]	3	hSpCas9	negative selection	7853282
15176031	15176054	11	-	27260156	NCIH2009	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.037131192506082225	[507]	[956,824,444]	0	hSpCas9	negative selection	7853283
15136617	15136640	11	-	27260156	NCIH2009	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-2.594232154329503	[184]	[53,17,58]	-9	hSpCas9	negative selection	7887272
15149187	15149210	11	-	27260156	NCIH2009	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.5260788977247302	[111]	[200,214,254]	7	hSpCas9	negative selection	7917538
15177142	15177165	11	+	27260156	NCIH2009	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.31999164625524235	[568]	[1429,881,751]	4	hSpCas9	negative selection	7917539
15177107	15177130	11	+	27260156	NCIH2009	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.35525888280690887	[445]	[494,381,586]	-5	hSpCas9	negative selection	7917540
15149216	15149239	11	-	27260156	NCIH1373	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.2704550090821112	[187]	[204,217,345,62]	2	hSpCas9	negative selection	7974532
15175932	15175955	11	+	27260156	NCIH1373	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.6778086283847391	[133]	[287,208,149,86]	6	hSpCas9	negative selection	7974533
15176031	15176054	11	-	27260156	NCIH1373	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.045332523994999416	[507]	[605,543,767,71]	0	hSpCas9	negative selection	7974534
15136617	15136640	11	-	27260156	NCIH1373	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-2.208411982856714	[184]	[18,28,113,2]	-9	hSpCas9	negative selection	8008523
15149187	15149210	11	-	27260156	NCIH1373	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.5177565752245075	[111]	[492,138,76,14]	5	hSpCas9	negative selection	8038789
15177142	15177165	11	+	27260156	NCIH1373	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.3715687639484688	[568]	[923,639,578,319]	3	hSpCas9	negative selection	8038790
15177107	15177130	11	+	27260156	NCIH1373	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.29348825300951276	[445]	[584,400,298,97]	-3	hSpCas9	negative selection	8038791
15149216	15149239	11	-	27260156	PATU8902	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.671755917058636	[187]	[169,320,756,319]	7	hSpCas9	negative selection	8095783
15175932	15175955	11	+	27260156	PATU8902	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.5449456089097087	[133]	[43,153,161,144]	-5	hSpCas9	negative selection	8095784
15176031	15176054	11	-	27260156	PATU8902	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.13837276692582845	[507]	[858,722,606,987]	1	hSpCas9	negative selection	8095785
15136617	15136640	11	-	27260156	PATU8902	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-4.5861329191758005	[184]	[1,24,1,16]	-9	hSpCas9	negative selection	8129774
15149187	15149210	11	-	27260156	PATU8902	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.8113173564815119	[111]	[205,677,99,139]	8	hSpCas9	negative selection	8160040
15177142	15177165	11	+	27260156	PATU8902	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.2105584169611977	[568]	[855,641,828,1415]	2	hSpCas9	negative selection	8160041
15177107	15177130	11	+	27260156	PATU8902	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.0037905176838357174	[445]	[714,577,390,877]	0	hSpCas9	negative selection	8160042
15149216	15149239	11	-	27260156	PANC1	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.48658046080693174	[187]	[208,315,197,200]	7	hSpCas9	negative selection	8217034
15175932	15175955	11	+	27260156	PANC1	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.2149116985185353	[133]	[95,91,55,141]	-3	hSpCas9	negative selection	8217035
15176031	15176054	11	-	27260156	PANC1	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.4039887880869607	[507]	[446,401,606,776]	6	hSpCas9	negative selection	8217036
15136617	15136640	11	-	27260156	PANC1	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.534851120147891	[184]	[6,47,91,68]	-9	hSpCas9	negative selection	8251025
15149187	15149210	11	-	27260156	PANC1	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.19663012051907613	[111]	[153,157,62,77]	3	hSpCas9	negative selection	8281291
15177142	15177165	11	+	27260156	PANC1	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.13888769219627822	[568]	[465,656,579,476]	2	hSpCas9	negative selection	8281292
15177107	15177130	11	+	27260156	PANC1	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.44006582313356474	[445]	[678,649,334,440]	7	hSpCas9	negative selection	8281293
15149216	15149239	11	-	27260156	PANC0813	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.6585872789600435	[187]	[357,269,451,316]	9	hSpCas9	negative selection	8338285
15175932	15175955	11	+	27260156	PANC0813	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.00363356655060576	[133]	[136,175,191,122]	0	hSpCas9	negative selection	8338286
15176031	15176054	11	-	27260156	PANC0813	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.14529115966087963	[507]	[686,430,463,585]	-2	hSpCas9	negative selection	8338287
15136617	15136640	11	-	27260156	PANC0813	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-2.4247257560434403	[184]	[30,22,47,57]	-9	hSpCas9	negative selection	8372276
15149187	15149210	11	-	27260156	PANC0813	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.811900121284195	[111]	[131,377,242,164]	9	hSpCas9	negative selection	8402542
15177142	15177165	11	+	27260156	PANC0813	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.24164237699344593	[568]	[848,720,835,760]	4	hSpCas9	negative selection	8402543
15177107	15177130	11	+	27260156	PANC0813	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.011462299789641112	[445]	[547,401,675,458]	0	hSpCas9	negative selection	8402544
15149216	15149239	11	-	27260156	RDES	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-0.22155689312661253	[187]	[203,187,211,116]	-4	hSpCas9	negative selection	8459536
15175932	15175955	11	+	27260156	RDES	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.10778177133527622	[133]	[137,152,123,152]	-2	hSpCas9	negative selection	8459537
15176031	15176054	11	-	27260156	RDES	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.8293133297254054	[507]	[324,214,334,461]	-8	hSpCas9	negative selection	8459538
15136617	15136640	11	-	27260156	RDES	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-2.11940477744248	[184]	[31,68,67,23]	-9	hSpCas9	negative selection	8493527
15149187	15149210	11	-	27260156	RDES	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.1942179923470515	[111]	[110,147,161,176]	3	hSpCas9	negative selection	8523793
15177142	15177165	11	+	27260156	RDES	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	-0.3066897355902877	[568]	[477,379,661,624]	-5	hSpCas9	negative selection	8523794
15177107	15177130	11	+	27260156	RDES	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.10554719099684642	[445]	[320,409,648,575]	-2	hSpCas9	negative selection	8523795
15149216	15149239	11	-	27260156	PC3	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.11049882396374944	[187]	[99,217,380,207]	2	hSpCas9	negative selection	8580787
15175932	15175955	11	+	27260156	PC3	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.6015954015040359	[133]	[36,165,72,80]	-8	hSpCas9	negative selection	8580788
15176031	15176054	11	-	27260156	PC3	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.12344144365563006	[507]	[212,395,784,679]	-3	hSpCas9	negative selection	8580789
15136617	15136640	11	-	27260156	PC3	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.7480861630723816	[184]	[35,75,38,63]	-9	hSpCas9	negative selection	8614778
15149187	15149210	11	-	27260156	PC3	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.34232461241578194	[111]	[63,120,260,193]	7	hSpCas9	negative selection	8645044
15177142	15177165	11	+	27260156	PC3	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.005291390605817181	[568]	[289,516,1100,659]	0	hSpCas9	negative selection	8645045
15177107	15177130	11	+	27260156	PC3	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.0066962501430642835	[445]	[297,396,566,599]	0	hSpCas9	negative selection	8645046
15149216	15149239	11	-	27260156	PATU8988T	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.2739826491020412	[187]	[327,197,217,124]	5	hSpCas9	negative selection	8702038
15175932	15175955	11	+	27260156	PATU8988T	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.454024256836582	[133]	[208,291,53,165]	7	hSpCas9	negative selection	8702039
15176031	15176054	11	-	27260156	PATU8988T	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.18144082071094642	[507]	[430,651,496,664]	3	hSpCas9	negative selection	8702040
15136617	15136640	11	-	27260156	PATU8988T	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-2.120821559528482	[184]	[36,33,66,23]	-9	hSpCas9	negative selection	8736029
15149187	15149210	11	-	27260156	PATU8988T	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.5983295221940361	[111]	[128,149,243,126]	8	hSpCas9	negative selection	8766295
15177142	15177165	11	+	27260156	PATU8988T	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.15933208428561724	[568]	[426,699,589,758]	2	hSpCas9	negative selection	8766296
15177107	15177130	11	+	27260156	PATU8988T	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.1946153774200019	[445]	[522,543,452,454]	3	hSpCas9	negative selection	8766297
15149216	15149239	11	-	27260156	T47D	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.6036124652920254	[187]	[353,348,301,324]	9	hSpCas9	negative selection	8823289
15175932	15175955	11	+	27260156	T47D	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.14051568250434676	[133]	[150,109,162,144]	-3	hSpCas9	negative selection	8823290
15176031	15176054	11	-	27260156	T47D	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	8.31472012621376e-05	[507]	[677,466,572,662]	0	hSpCas9	negative selection	8823291
15136617	15136640	11	-	27260156	T47D	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.8762265334722512	[184]	[63,56,55,57]	-9	hSpCas9	negative selection	8857280
15149187	15149210	11	-	27260156	T47D	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.23162805959773936	[111]	[144,111,194,163]	5	hSpCas9	negative selection	8887546
15177142	15177165	11	+	27260156	T47D	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	-0.024411073934424876	[568]	[594,656,646,708]	0	hSpCas9	negative selection	8887547
15177107	15177130	11	+	27260156	T47D	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.22053744084550803	[445]	[534,540,672,678]	5	hSpCas9	negative selection	8887548
15149216	15149239	11	-	27260156	SU8686	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.6280359057162181	[187]	[203,298,322,341]	9	hSpCas9	negative selection	8944540
15175932	15175955	11	+	27260156	SU8686	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.2619775126074977	[133]	[105,182,184,166]	4	hSpCas9	negative selection	8944541
15176031	15176054	11	-	27260156	SU8686	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	0.37033699980450185	[507]	[665,470,640,879]	6	hSpCas9	negative selection	8944542
15136617	15136640	11	-	27260156	SU8686	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-2.816706803258314	[184]	[21,18,48,13]	-9	hSpCas9	negative selection	8978531
15149187	15149210	11	-	27260156	SU8686	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.32832059752708287	[111]	[140,142,161,104]	5	hSpCas9	negative selection	9008797
15177142	15177165	11	+	27260156	SU8686	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	0.22585894673630358	[568]	[487,576,763,872]	4	hSpCas9	negative selection	9008798
15177107	15177130	11	+	27260156	SU8686	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.13840690173260098	[445]	[313,377,442,498]	-2	hSpCas9	negative selection	9008799
15149216	15149239	11	-	27260156	SKES1	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.2906202958144013	[187]	[198,295,159,260]	6	hSpCas9	negative selection	9065791
15175932	15175955	11	+	27260156	SKES1	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.5733573482900309	[133]	[116,232,135,289]	9	hSpCas9	negative selection	9065792
15176031	15176054	11	-	27260156	SKES1	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.19088189334502084	[507]	[478,464,555,294]	-4	hSpCas9	negative selection	9065793
15136617	15136640	11	-	27260156	SKES1	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.609237526831575	[184]	[70,62,35,71]	-9	hSpCas9	negative selection	9099782
15149187	15149210	11	-	27260156	SKES1	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.25181254262407604	[111]	[183,130,88,133]	5	hSpCas9	negative selection	9130048
15177142	15177165	11	+	27260156	SKES1	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	-0.13483242732423173	[568]	[439,600,452,562]	-3	hSpCas9	negative selection	9130049
15177107	15177130	11	+	27260156	SKES1	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.07259046241975933	[445]	[438,492,370,398]	-1	hSpCas9	negative selection	9130050
15149216	15149239	11	-	27260156	TOV112D	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.23225667663497096	[187]	[267,258,199,171]	4	hSpCas9	negative selection	9187042
15175932	15175955	11	+	27260156	TOV112D	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.12803230244352815	[133]	[157,167,133,132]	2	hSpCas9	negative selection	9187043
15176031	15176054	11	-	27260156	TOV112D	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.32667592354427155	[507]	[397,401,503,318]	-6	hSpCas9	negative selection	9187044
15136617	15136640	11	-	27260156	TOV112D	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-0.5794652119141697	[184]	[33,64,80,288]	-8	hSpCas9	negative selection	9221033
15149187	15149210	11	-	27260156	TOV112D	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.11383128099829554	[111]	[132,99,124,122]	2	hSpCas9	negative selection	9251299
15177142	15177165	11	+	27260156	TOV112D	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	-0.007542479109147959	[568]	[730,629,583,356]	0	hSpCas9	negative selection	9251300
15177107	15177130	11	+	27260156	TOV112D	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	-0.22642863806805646	[445]	[342,527,403,286]	-4	hSpCas9	negative selection	9251301
15149216	15149239	11	-	27260156	TC71	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.24681087620508468	[187]	[247,241,253,209]	6	hSpCas9	negative selection	9308293
15175932	15175955	11	+	27260156	TC71	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.15933516747841603	[133]	[116,181,78,138]	-4	hSpCas9	negative selection	9308294
15176031	15176054	11	-	27260156	TC71	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.16356812783240937	[507]	[450,415,539,539]	-4	hSpCas9	negative selection	9308295
15136617	15136640	11	-	27260156	TC71	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.1755411124999409	[184]	[138,56,73,79]	-9	hSpCas9	negative selection	9342284
15149187	15149210	11	-	27260156	TC71	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.0070185193736564955	[111]	[120,100,88,175]	0	hSpCas9	negative selection	9372550
15177142	15177165	11	+	27260156	TC71	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	-0.05159147855262364	[568]	[587,572,568,626]	-1	hSpCas9	negative selection	9372551
15177107	15177130	11	+	27260156	TC71	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.11755794181181256	[445]	[607,533,544,375]	3	hSpCas9	negative selection	9372552
15149216	15149239	11	-	27260156	TC32	viability	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.37386861668144933	[187]	[223,223,245,210]	6	hSpCas9	negative selection	9429544
15175932	15175955	11	+	27260156	TC32	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.19114049094116092	[133]	[49,114,120,158]	-3	hSpCas9	negative selection	9429545
15176031	15176054	11	-	27260156	TC32	viability	AGCACTGTACTCGCTGACCATGG	INSC	ENSG00000188487	-0.6183333908019885	[507]	[245,207,457,391]	-8	hSpCas9	negative selection	9429546
15136617	15136640	11	-	27260156	TC32	viability	TTATGGATGAGCAAAGAAAGAAG	INSC	ENSG00000188487	-1.5768533009210213	[184]	[101,2,59,81]	-9	hSpCas9	negative selection	9463535
15149187	15149210	11	-	27260156	TC32	viability	GAGTCCAGGTGGCGACCTCCAGG	INSC	ENSG00000188487	0.4852617350455337	[111]	[147,140,132,157]	8	hSpCas9	negative selection	9493801
15177142	15177165	11	+	27260156	TC32	viability	AGCTCTCGGCAGTCACAGAGAGG	INSC	ENSG00000188487	-0.32836428331144746	[568]	[459,191,440,688]	-6	hSpCas9	negative selection	9493802
15177107	15177130	11	+	27260156	TC32	viability	ACAGATTGAGAAGCTGCTAATGG	INSC	ENSG00000188487	0.286925109255583	[445]	[324,671,474,492]	5	hSpCas9	negative selection	9493803
15112488	15112511	11	+	27869803	HPAFII	viability after 27 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	1.1249123034468442	[226]	[70,417,NaN]	8	hSpCas9	negative selection	9540746
15149216	15149239	11	-	27869803	HPAFII	viability after 27 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.028863790212884988	[69]	[0,67,NaN]	0	hSpCas9	negative selection	9540747
15175738	15175761	11	+	27869803	HPAFII	viability after 27 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-0.29535854588029176	[319]	[9,242,NaN]	-2	hSpCas9	negative selection	9540748
15178368	15178391	11	-	27869803	HPAFII	viability after 27 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	1.286783682662013	[272]	[545,186,NaN]	9	hSpCas9	negative selection	9540749
15190792	15190815	11	-	27869803	HPAFII	viability after 27 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	-0.6326648786823477	[362]	[133,113,NaN]	-4	hSpCas9	negative selection	9540750
15200841	15200864	11	+	27869803	HPAFII	viability after 27 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	-0.9793101412328151	[59]	[21,10,NaN]	-6	hSpCas9	negative selection	9540751
15112488	15112511	11	+	27869803	HPAFII	viability after 15 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	0.6957989758884698	[226]	[232,495,NaN]	7	hSpCas9	negative selection	9623195
15149216	15149239	11	-	27869803	HPAFII	viability after 15 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-0.18454419370952002	[69]	[43,79,NaN]	-2	hSpCas9	negative selection	9623196
15175738	15175761	11	+	27869803	HPAFII	viability after 15 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-0.8489407078599978	[319]	[66,267,NaN]	-7	hSpCas9	negative selection	9623197
15178368	15178391	11	-	27869803	HPAFII	viability after 15 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	0.3082735019078229	[272]	[678,166,NaN]	3	hSpCas9	negative selection	9623198
15190792	15190815	11	-	27869803	HPAFII	viability after 15 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	-0.4734825567886688	[362]	[407,201,NaN]	-5	hSpCas9	negative selection	9623199
15200841	15200864	11	+	27869803	HPAFII	viability after 15 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	0.6292139515324107	[59]	[153,65,NaN]	7	hSpCas9	negative selection	9623200
15112488	15112511	11	+	27869803	ASPC1	viability after 36 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	-0.2668647890845458	[509]	[335,72,73]	-3	hSpCas9	negative selection	9705644
15149216	15149239	11	-	27869803	ASPC1	viability after 36 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-0.8665922365380867	[158]	[0,9,66]	-7	hSpCas9	negative selection	9705645
15175738	15175761	11	+	27869803	ASPC1	viability after 36 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-0.14924709576940443	[516]	[250,245,32]	-1	hSpCas9	negative selection	9705646
15178368	15178391	11	-	27869803	ASPC1	viability after 36 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	0.8893605660627739	[767]	[316,423,674]	8	hSpCas9	negative selection	9705647
15190792	15190815	11	-	27869803	ASPC1	viability after 36 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	0.28039216179617926	[744]	[355,406,211]	3	hSpCas9	negative selection	9705648
15200841	15200864	11	+	27869803	ASPC1	viability after 36 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	0.6104458425500287	[246]	[331,66,40]	6	hSpCas9	negative selection	9705649
15112488	15112511	11	+	27869803	PATU8988S	viability after 35 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	-0.6063126808998045	[456]	[77,163,NaN]	-6	hSpCas9	negative selection	9788093
15149216	15149239	11	-	27869803	PATU8988S	viability after 35 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.7911909045641308	[86]	[119,0,NaN]	8	hSpCas9	negative selection	9788094
15175738	15175761	11	+	27869803	PATU8988S	viability after 35 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	0.034748957332933386	[543]	[196,251,NaN]	0	hSpCas9	negative selection	9788095
15178368	15178391	11	-	27869803	PATU8988S	viability after 35 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	0.6373842588786969	[761]	[204,750,NaN]	7	hSpCas9	negative selection	9788096
15190792	15190815	11	-	27869803	PATU8988S	viability after 35 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	-0.651261638002442	[820]	[226,193,NaN]	-6	hSpCas9	negative selection	9788097
15200841	15200864	11	+	27869803	PATU8988S	viability after 35 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	-1.31643502078765	[274]	[31,56,NaN]	-8	hSpCas9	negative selection	9788098
15112488	15112511	11	+	27869803	PATU8988S	viability after 31 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	-0.6521381036098204	[456]	[100,134,NaN]	-6	hSpCas9	negative selection	9870542
15149216	15149239	11	-	27869803	PATU8988S	viability after 31 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.09005635618376528	[86]	[61,4,NaN]	1	hSpCas9	negative selection	9870543
15175738	15175761	11	+	27869803	PATU8988S	viability after 31 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	0.08892533854273199	[543]	[169,307,NaN]	1	hSpCas9	negative selection	9870544
15178368	15178391	11	-	27869803	PATU8988S	viability after 31 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	0.6626586764332938	[761]	[198,839,NaN]	7	hSpCas9	negative selection	9870545
15190792	15190815	11	-	27869803	PATU8988S	viability after 31 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	-0.2431446252421759	[820]	[247,312,NaN]	-3	hSpCas9	negative selection	9870546
15200841	15200864	11	+	27869803	PATU8988S	viability after 31 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	-0.3187279265330184	[274]	[79,97,NaN]	-4	hSpCas9	negative selection	9870547
15112488	15112511	11	+	27869803	HPAFII	viability after 35 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	0.9669115859501419	[226]	[59,409,NaN]	6	hSpCas9	negative selection	9952991
15149216	15149239	11	-	27869803	HPAFII	viability after 35 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	0.46180172897252336	[69]	[13,87,NaN]	3	hSpCas9	negative selection	9952992
15175738	15175761	11	+	27869803	HPAFII	viability after 35 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-0.2425152236278594	[319]	[0,289,NaN]	-1	hSpCas9	negative selection	9952993
15178368	15178391	11	-	27869803	HPAFII	viability after 35 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	1.2842939291063848	[272]	[393,271,NaN]	8	hSpCas9	negative selection	9952994
15190792	15190815	11	-	27869803	HPAFII	viability after 35 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	-0.22319912221316163	[362]	[187,122,NaN]	-1	hSpCas9	negative selection	9952995
15200841	15200864	11	+	27869803	HPAFII	viability after 35 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	-1.8729966547288859	[59]	[4,11,NaN]	-7	hSpCas9	negative selection	9952996
15112488	15112511	11	+	27869803	HPAFII	viability after 31 days	AATGGAGAGGCGGCCAGCGAAGG	INSC	ENSG00000188487	1.1654684630162628	[226]	[123,461,NaN]	8	hSpCas9	negative selection	10035440
15149216	15149239	11	-	27869803	HPAFII	viability after 31 days	GGACTTACCGCTGACCCGGCAGG	INSC	ENSG00000188487	-0.7234551955403241	[69]	[7,40,NaN]	-5	hSpCas9	negative selection	10035441
15175738	15175761	11	+	27869803	HPAFII	viability after 31 days	CAGGCTACACCTGATGCAGGTGG	INSC	ENSG00000188487	-0.9072486936503152	[319]	[0,198,NaN]	-5	hSpCas9	negative selection	10035442
15178368	15178391	11	-	27869803	HPAFII	viability after 31 days	GCTCAGGGTCTCACTCACGCAGG	INSC	ENSG00000188487	1.420345476969071	[272]	[500,310,NaN]	9	hSpCas9	negative selection	10035443
15190792	15190815	11	-	27869803	HPAFII	viability after 31 days	CTTGGCTATGATGCGGCACAAGG	INSC	ENSG00000188487	-0.8951029335973087	[362]	[143,71,NaN]	-5	hSpCas9	negative selection	10035444
15200841	15200864	11	+	27869803	HPAFII	viability after 31 days	ACTCTTCAAGGTTTGCCGGCAGG	INSC	ENSG00000188487	-1.0228933228632928	[59]	[6,26,NaN]	-6	hSpCas9	negative selection	10035445
15175768	15175791	11	-	28162770	P31FUJ	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	0.11330570296811032	[283]	[360]	1	hSpCas9	negative selection	10175040
15175954	15175977	11	+	28162770	P31FUJ	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	0.0678153842275715	[340]	[419]	0	hSpCas9	negative selection	10175041
15175932	15175955	11	+	28162770	P31FUJ	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.8583456836438168	[160]	[342]	8	hSpCas9	negative selection	10175042
15178345	15178368	11	+	28162770	P31FUJ	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.7796289451344343	[519]	[1048]	8	hSpCas9	negative selection	10175043
15178420	15178443	11	+	28162770	P31FUJ	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	-1.6113138276681085	[90]	[34]	-7	hSpCas9	negative selection	10175044
15221571	15221594	11	-	28162770	P31FUJ	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-4.8766583941891035	[24]	[0]	-9	hSpCas9	negative selection	10175045
15225692	15225715	11	-	28162770	P31FUJ	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	0.6036990633027418	[181]	[324]	7	hSpCas9	negative selection	10175046
15149172	15149195	11	+	28162770	P31FUJ	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	-0.1113386919287116	[147]	[160]	-1	hSpCas9	negative selection	10175047
15149198	15149221	11	-	28162770	P31FUJ	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.49810799768928005	[190]	[316]	5	hSpCas9	negative selection	10175048
15175901	15175924	11	-	28162770	P31FUJ	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	0.8566127164193611	[390]	[831]	8	hSpCas9	negative selection	10175049
15175768	15175791	11	-	28162770	TF1	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	NaN	[NaN]	[391]	1	hSpCas9	negative selection	10344406
15175954	15175977	11	+	28162770	TF1	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	NaN	[NaN]	[281]	1	hSpCas9	negative selection	10344407
15175932	15175955	11	+	28162770	TF1	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	NaN	[NaN]	[204]	1	hSpCas9	negative selection	10344408
15178345	15178368	11	+	28162770	TF1	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	NaN	[NaN]	[487]	1	hSpCas9	negative selection	10344409
15178420	15178443	11	+	28162770	TF1	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10344410
15221571	15221594	11	-	28162770	TF1	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10344411
15225692	15225715	11	-	28162770	TF1	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	NaN	[NaN]	[219]	1	hSpCas9	negative selection	10344412
15149172	15149195	11	+	28162770	TF1	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10344413
15149198	15149221	11	-	28162770	TF1	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	NaN	[NaN]	[94]	1	hSpCas9	negative selection	10344414
15175901	15175924	11	-	28162770	TF1	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	NaN	[NaN]	[415]	1	hSpCas9	negative selection	10344415
15175768	15175791	11	-	28162770	SKM1	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	-0.20051332127573535	[90]	[139]	-2	hSpCas9	negative selection	10513772
15175954	15175977	11	+	28162770	SKM1	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	0.44547861284298046	[53]	[129]	4	hSpCas9	negative selection	10513773
15175932	15175955	11	+	28162770	SKM1	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.22064263938648815	[49]	[102]	2	hSpCas9	negative selection	10513774
15178345	15178368	11	+	28162770	SKM1	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.34250980723394253	[177]	[398]	3	hSpCas9	negative selection	10513775
15178420	15178443	11	+	28162770	SKM1	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	-1.6520766965796931	[15]	[8]	-8	hSpCas9	negative selection	10513776
15221571	15221594	11	-	28162770	SKM1	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	0.7629608026991508	[3]	[11]	7	hSpCas9	negative selection	10513777
15225692	15225715	11	-	28162770	SKM1	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	-0.12365739788310665	[52]	[85]	-1	hSpCas9	negative selection	10513778
15149172	15149195	11	+	28162770	SKM1	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	0.22690790245894077	[28]	[59]	2	hSpCas9	negative selection	10513779
15149198	15149221	11	-	28162770	SKM1	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.2934755193979304	[35]	[77]	3	hSpCas9	negative selection	10513780
15175901	15175924	11	-	28162770	SKM1	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	0.12497991967850341	[96]	[186]	1	hSpCas9	negative selection	10513781
15175768	15175791	11	-	28162770	SKM1	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	-0.20051332127573535	[90]	[139]	-2	hSpCas9	negative selection	10683138
15175954	15175977	11	+	28162770	SKM1	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	0.44547861284298046	[53]	[129]	4	hSpCas9	negative selection	10683139
15175932	15175955	11	+	28162770	SKM1	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.22064263938648815	[49]	[102]	2	hSpCas9	negative selection	10683140
15178345	15178368	11	+	28162770	SKM1	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.34250980723394253	[177]	[398]	3	hSpCas9	negative selection	10683141
15178420	15178443	11	+	28162770	SKM1	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	-1.6520766965796931	[15]	[8]	-8	hSpCas9	negative selection	10683142
15221571	15221594	11	-	28162770	SKM1	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	0.7629608026991508	[3]	[11]	7	hSpCas9	negative selection	10683143
15225692	15225715	11	-	28162770	SKM1	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	-0.12365739788310665	[52]	[85]	-1	hSpCas9	negative selection	10683144
15149172	15149195	11	+	28162770	SKM1	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	0.22690790245894077	[28]	[59]	2	hSpCas9	negative selection	10683145
15149198	15149221	11	-	28162770	SKM1	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.2934755193979304	[35]	[77]	3	hSpCas9	negative selection	10683146
15175901	15175924	11	-	28162770	SKM1	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	0.12497991967850341	[96]	[186]	1	hSpCas9	negative selection	10683147
15175768	15175791	11	-	28162770	PL21	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	0.6968155827925214	[291]	[205]	6	hSpCas9	negative selection	10852504
15175954	15175977	11	+	28162770	PL21	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	1.753830653554194	[170]	[250]	9	hSpCas9	negative selection	10852505
15175932	15175955	11	+	28162770	PL21	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.28528721268092155	[167]	[59]	-2	hSpCas9	negative selection	10852506
15178345	15178368	11	+	28162770	PL21	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.7018554125874619	[540]	[382]	6	hSpCas9	negative selection	10852507
15178420	15178443	11	+	28162770	PL21	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	-0.543084970148568	[76]	[22]	-4	hSpCas9	negative selection	10852508
15221571	15221594	11	-	28162770	PL21	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-0.5160674195100885	[22]	[6]	-4	hSpCas9	negative selection	10852509
15225692	15225715	11	-	28162770	PL21	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	0.23490503264999668	[163]	[83]	2	hSpCas9	negative selection	10852510
15149172	15149195	11	+	28162770	PL21	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	-0.17837200876440956	[142]	[54]	-1	hSpCas9	negative selection	10852511
15149198	15149221	11	-	28162770	PL21	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	-2.173318781038124	[113]	[10]	-8	hSpCas9	negative selection	10852512
15175901	15175924	11	-	28162770	PL21	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	0.29216875298166567	[333]	[177]	2	hSpCas9	negative selection	10852513
15175768	15175791	11	-	28162770	P31FUJ	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	0.11330570296811032	[283]	[360]	1	hSpCas9	negative selection	11021870
15175954	15175977	11	+	28162770	P31FUJ	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	0.0678153842275715	[340]	[419]	0	hSpCas9	negative selection	11021871
15175932	15175955	11	+	28162770	P31FUJ	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.8583456836438168	[160]	[342]	8	hSpCas9	negative selection	11021872
15178345	15178368	11	+	28162770	P31FUJ	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.7796289451344343	[519]	[1048]	8	hSpCas9	negative selection	11021873
15178420	15178443	11	+	28162770	P31FUJ	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	-1.6113138276681085	[90]	[34]	-7	hSpCas9	negative selection	11021874
15221571	15221594	11	-	28162770	P31FUJ	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-4.8766583941891035	[24]	[0]	-9	hSpCas9	negative selection	11021875
15225692	15225715	11	-	28162770	P31FUJ	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	0.6036990633027418	[181]	[324]	7	hSpCas9	negative selection	11021876
15149172	15149195	11	+	28162770	P31FUJ	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	-0.1113386919287116	[147]	[160]	-1	hSpCas9	negative selection	11021877
15149198	15149221	11	-	28162770	P31FUJ	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.49810799768928005	[190]	[316]	5	hSpCas9	negative selection	11021878
15175901	15175924	11	-	28162770	P31FUJ	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	0.8566127164193611	[390]	[831]	8	hSpCas9	negative selection	11021879
15175768	15175791	11	-	28162770	OCIAML5	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	0.12284244817317258	[173]	[341]	1	hSpCas9	negative selection	11191236
15175954	15175977	11	+	28162770	OCIAML5	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	0.18135643067345328	[127]	[261]	1	hSpCas9	negative selection	11191237
15175932	15175955	11	+	28162770	OCIAML5	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.30250940627403944	[109]	[160]	-2	hSpCas9	negative selection	11191238
15178345	15178368	11	+	28162770	OCIAML5	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.29954655230137384	[369]	[821]	2	hSpCas9	negative selection	11191239
15178420	15178443	11	+	28162770	OCIAML5	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.05482402474452175	[31]	[59]	0	hSpCas9	negative selection	11191240
15221571	15221594	11	-	28162770	OCIAML5	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-2.4370290715851533	[8]	[2]	-8	hSpCas9	negative selection	11191241
15225692	15225715	11	-	28162770	OCIAML5	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	0.5972408304995931	[129]	[354]	5	hSpCas9	negative selection	11191242
15149172	15149195	11	+	28162770	OCIAML5	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	0.7241257202294271	[54]	[163]	6	hSpCas9	negative selection	11191243
15149198	15149221	11	-	28162770	OCIAML5	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.5119869996960418	[53]	[138]	4	hSpCas9	negative selection	11191244
15175901	15175924	11	-	28162770	OCIAML5	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	0.3940374390199195	[249]	[592]	3	hSpCas9	negative selection	11191245
15175768	15175791	11	-	28162770	EOL1	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	1.1796334242888373	[454]	[542]	8	hSpCas9	negative selection	11360602
15175954	15175977	11	+	28162770	EOL1	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	0.4079722458296286	[205]	[143]	4	hSpCas9	negative selection	11360603
15175932	15175955	11	+	28162770	EOL1	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.5112712898448124	[302]	[111]	-4	hSpCas9	negative selection	11360604
15178345	15178368	11	+	28162770	EOL1	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.47755880439037024	[836]	[613]	4	hSpCas9	negative selection	11360605
15178420	15178443	11	+	28162770	EOL1	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	-1.162915069679805	[101]	[23]	-7	hSpCas9	negative selection	11360606
15221571	15221594	11	-	28162770	EOL1	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-2.245377229871778	[17]	[1]	-8	hSpCas9	negative selection	11360607
15225692	15225715	11	-	28162770	EOL1	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	0.7069563364979077	[199]	[171]	6	hSpCas9	negative selection	11360608
15149172	15149195	11	+	28162770	EOL1	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	0.22711054159096566	[179]	[110]	2	hSpCas9	negative selection	11360609
15149198	15149221	11	-	28162770	EOL1	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.19830858399738682	[133]	[80]	1	hSpCas9	negative selection	11360610
15175901	15175924	11	-	28162770	EOL1	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	0.7565647478624079	[463]	[412]	6	hSpCas9	negative selection	11360611
15175768	15175791	11	-	28162770	MOLM13	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	0.25402103251466956	[449]	[387]	1	hSpCas9	negative selection	11529968
15175954	15175977	11	+	28162770	MOLM13	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	-0.5616146127655044	[246]	[120]	-3	hSpCas9	negative selection	11529969
15175932	15175955	11	+	28162770	MOLM13	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.10461330995547678	[291]	[226]	0	hSpCas9	negative selection	11529970
15178345	15178368	11	+	28162770	MOLM13	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.6659573473325955	[862]	[989]	5	hSpCas9	negative selection	11529971
15178420	15178443	11	+	28162770	MOLM13	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.5298171306877805	[113]	[118]	4	hSpCas9	negative selection	11529972
15221571	15221594	11	-	28162770	MOLM13	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-3.6195734597057614	[16]	[0]	-9	hSpCas9	negative selection	11529973
15225692	15225715	11	-	28162770	MOLM13	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	-0.2535751190814394	[215]	[130]	-1	hSpCas9	negative selection	11529974
15149172	15149195	11	+	28162770	MOLM13	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	0.46788938154457893	[136]	[136]	3	hSpCas9	negative selection	11529975
15149198	15149221	11	-	28162770	MOLM13	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.3582648903700806	[163]	[151]	2	hSpCas9	negative selection	11529976
15175901	15175924	11	-	28162770	MOLM13	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	-0.6343154787823198	[540]	[251]	-4	hSpCas9	negative selection	11529977
15175768	15175791	11	-	28162770	HEL	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	1.4318420495017383	[374]	[647]	9	hSpCas9	negative selection	11699334
15175954	15175977	11	+	28162770	HEL	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	0.26493423892048845	[203]	[156]	2	hSpCas9	negative selection	11699335
15175932	15175955	11	+	28162770	HEL	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.9028616424142475	[247]	[296]	7	hSpCas9	negative selection	11699336
15178345	15178368	11	+	28162770	HEL	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	1.0736387170981687	[700]	[944]	8	hSpCas9	negative selection	11699337
15178420	15178443	11	+	28162770	HEL	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	1.0577763312792006	[74]	[99]	8	hSpCas9	negative selection	11699338
15221571	15221594	11	-	28162770	HEL	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-2.6791892628870055	[29]	[2]	-8	hSpCas9	negative selection	11699339
15225692	15225715	11	-	28162770	HEL	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	0.6108547709805707	[182]	[178]	5	hSpCas9	negative selection	11699340
15149172	15149195	11	+	28162770	HEL	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	0.14253394945883607	[156]	[110]	1	hSpCas9	negative selection	11699341
15149198	15149221	11	-	28162770	HEL	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	-0.05469839797921194	[119]	[73]	0	hSpCas9	negative selection	11699342
15175901	15175924	11	-	28162770	HEL	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	0.5546079217216918	[404]	[380]	5	hSpCas9	negative selection	11699343
15175768	15175791	11	-	28162770	MV411	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	0.9604432460048	[254]	[417]	8	hSpCas9	negative selection	11868700
15175954	15175977	11	+	28162770	MV411	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	0.869357807502601	[166]	[256]	7	hSpCas9	negative selection	11868701
15175932	15175955	11	+	28162770	MV411	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	1.028797264307435	[127]	[219]	8	hSpCas9	negative selection	11868702
15178345	15178368	11	+	28162770	MV411	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.4084999835152916	[507]	[567]	3	hSpCas9	negative selection	11868703
15178420	15178443	11	+	28162770	MV411	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	0.669670551465823	[49]	[66]	6	hSpCas9	negative selection	11868704
15221571	15221594	11	-	28162770	MV411	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-1.415527461939654	[18]	[5]	-7	hSpCas9	negative selection	11868705
15225692	15225715	11	-	28162770	MV411	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	0.060234557908627494	[188]	[165]	0	hSpCas9	negative selection	11868706
15149172	15149195	11	+	28162770	MV411	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	0.037514481408544076	[95]	[82]	0	hSpCas9	negative selection	11868707
15149198	15149221	11	-	28162770	MV411	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.8242261200582315	[117]	[175]	7	hSpCas9	negative selection	11868708
15175901	15175924	11	-	28162770	MV411	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	0.3209665862047405	[305]	[321]	3	hSpCas9	negative selection	11868709
15175768	15175791	11	-	28162770	MONOMAC1	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	-0.32551140500836273	[222]	[203]	-3	hSpCas9	negative selection	12038066
15175954	15175977	11	+	28162770	MONOMAC1	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	1.1925299647031717	[149]	[392]	9	hSpCas9	negative selection	12038067
15175932	15175955	11	+	28162770	MONOMAC1	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	-0.7065091481964465	[120]	[84]	-5	hSpCas9	negative selection	12038068
15178345	15178368	11	+	28162770	MONOMAC1	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.10012334267886658	[375]	[461]	1	hSpCas9	negative selection	12038069
15178420	15178443	11	+	28162770	MONOMAC1	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	-0.39867070822920403	[45]	[39]	-3	hSpCas9	negative selection	12038070
15221571	15221594	11	-	28162770	MONOMAC1	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-2.419429268396002	[13]	[2]	-9	hSpCas9	negative selection	12038071
15225692	15225715	11	-	28162770	MONOMAC1	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	-0.1425890630371772	[129]	[134]	-1	hSpCas9	negative selection	12038072
15149172	15149195	11	+	28162770	MONOMAC1	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	0.7276750256362091	[58]	[111]	7	hSpCas9	negative selection	12038073
15149198	15149221	11	-	28162770	MONOMAC1	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	-0.5789074824031982	[85]	[65]	-5	hSpCas9	negative selection	12038074
15175901	15175924	11	-	28162770	MONOMAC1	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	-0.46007125289334766	[227]	[189]	-4	hSpCas9	negative selection	12038075
15175768	15175791	11	-	28162770	OCIAML2	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	0.18423468870915116	[46]	[295]	1	hSpCas9	negative selection	12207432
15175954	15175977	11	+	28162770	OCIAML2	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	0.07585852766435928	[37]	[221]	0	hSpCas9	negative selection	12207433
15175932	15175955	11	+	28162770	OCIAML2	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	1.3564074626771425	[25]	[368]	9	hSpCas9	negative selection	12207434
15178345	15178368	11	+	28162770	OCIAML2	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.5572254588106824	[108]	[888]	5	hSpCas9	negative selection	12207435
15178420	15178443	11	+	28162770	OCIAML2	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	-1.3662931654274257	[19]	[42]	-7	hSpCas9	negative selection	12207436
15221571	15221594	11	-	28162770	OCIAML2	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	-0.7701901071010693	[3]	[12]	-5	hSpCas9	negative selection	12207437
15225692	15225715	11	-	28162770	OCIAML2	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	0.27187395246547497	[38]	[260]	2	hSpCas9	negative selection	12207438
15149172	15149195	11	+	28162770	OCIAML2	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	0.4038392926739798	[11]	[87]	4	hSpCas9	negative selection	12207439
15149198	15149221	11	-	28162770	OCIAML2	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	0.8283371212018901	[18]	[186]	7	hSpCas9	negative selection	12207440
15175901	15175924	11	-	28162770	OCIAML2	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	0.42983450120692435	[59]	[447]	4	hSpCas9	negative selection	12207441
15175768	15175791	11	-	28162770	OCIAML3	viability	TCAGATCTTCCATCCAGCGCTGG	INSC	ENSG00000188487	-0.1817472257158929	[64]	[172]	-1	hSpCas9	negative selection	12376798
15175954	15175977	11	+	28162770	OCIAML3	viability	GATCGGGCAGAAGCTGGCCCAGG	INSC	ENSG00000188487	1.4672395485023773	[48]	[408]	9	hSpCas9	negative selection	12376799
15175932	15175955	11	+	28162770	OCIAML3	viability	TCATTAGCACAGAGCTGCGCAGG	INSC	ENSG00000188487	0.010854417834697816	[47]	[145]	0	hSpCas9	negative selection	12376800
15178345	15178368	11	+	28162770	OCIAML3	viability	GCATGTCCTGAAGTCAATGAAGG	INSC	ENSG00000188487	0.40150496868352303	[160]	[641]	4	hSpCas9	negative selection	12376801
15178420	15178443	11	+	28162770	OCIAML3	viability	GGAGCTGGCCCTGACACGGGAGG	INSC	ENSG00000188487	-0.28915305879574205	[16]	[41]	-2	hSpCas9	negative selection	12376802
15221571	15221594	11	-	28162770	OCIAML3	viability	GGTGACGGGCAGGTGTGGGGAGG	INSC	ENSG00000188487	1.1064320778169292	[5]	[38]	8	hSpCas9	negative selection	12376803
15225692	15225715	11	-	28162770	OCIAML3	viability	GATGTTGGCAAGGGCCGCAGAGG	INSC	ENSG00000188487	0.6572174632199972	[45]	[218]	6	hSpCas9	negative selection	12376804
15149172	15149195	11	+	28162770	OCIAML3	viability	AACATGATGGCACTGCCTGGAGG	INSC	ENSG00000188487	1.222685146312777	[21]	[154]	8	hSpCas9	negative selection	12376805
15149198	15149221	11	-	28162770	OCIAML3	viability	GCAGGGTGACGGAGTCCAGGTGG	INSC	ENSG00000188487	-0.18738238086151943	[42]	[113]	-1	hSpCas9	negative selection	12376806
15175901	15175924	11	-	28162770	OCIAML3	viability	CGTTTGAGCAGCAGCTGCAGGGG	INSC	ENSG00000188487	0.3914927899807219	[74]	[296]	3	hSpCas9	negative selection	12376807