Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 9922
• Symbol: IQSEC1
• Description: IQ motif and Sec7 domain ArfGEF 1

DataSource: http://genomecrispr.dkfz.de/#!/results/IQSEC1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
12936353	12936376	3	+	26472758	Jiyoye	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.006637451922144599	[98]	[74]	0	hSpCas9	negative selection	79019
12920503	12920526	3	+	26472758	Jiyoye	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	-0.07614685733944504	[136]	[97]	0	hSpCas9	negative selection	79020
12941688	12941711	3	-	26472758	Jiyoye	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	1.2627854721706986	[20]	[37]	7	hSpCas9	negative selection	79021
12936622	12936645	3	+	26472758	Jiyoye	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.5402008001366567	[175]	[192]	4	hSpCas9	negative selection	79022
12936169	12936192	3	+	26472758	Jiyoye	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.15760923727765247	[141]	[95]	-1	hSpCas9	negative selection	79023
12935904	12935927	3	+	26472758	Jiyoye	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	1.0753318177534283	[72]	[115]	7	hSpCas9	negative selection	79024
12924573	12924596	3	+	26472758	Jiyoye	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	0.08159950960336679	[98]	[78]	0	hSpCas9	negative selection	79025
12922154	12922177	3	-	26472758	Jiyoye	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	5.655102894949458	[0]	[37]	9	hSpCas9	negative selection	79026
12922137	12922160	3	-	26472758	Jiyoye	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	-0.019089373196224613	[85]	[63]	0	hSpCas9	negative selection	79027
12920553	12920576	3	+	26472758	Jiyoye	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	1.7994928042846334	[55]	[146]	8	hSpCas9	negative selection	79028
12936353	12936376	3	+	26472758	KBM7	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	1.0545358270898744	[348,297]	[542,110]	9	hSpCas9	negative selection	270137
12920503	12920526	3	+	26472758	KBM7	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	0.5042825047170795	[621,387]	[387,278]	5	hSpCas9	negative selection	270138
12941688	12941711	3	-	26472758	KBM7	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	0.9729353371538265	[144,113]	[134,103]	9	hSpCas9	negative selection	270139
12936622	12936645	3	+	26472758	KBM7	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.2876151390007461	[922,665]	[645,275]	3	hSpCas9	negative selection	270140
12936169	12936192	3	+	26472758	KBM7	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.4989774579499828	[519,514]	[328,359]	5	hSpCas9	negative selection	270141
12935904	12935927	3	+	26472758	KBM7	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	0.2756748945694667	[336,272]	[170,173]	3	hSpCas9	negative selection	270142
12924573	12924596	3	+	26472758	KBM7	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.09887007995409999	[535,562]	[147,327]	-1	hSpCas9	negative selection	270143
12922154	12922177	3	-	26472758	KBM7	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	-0.3450358125070301	[230,120]	[74,52]	-3	hSpCas9	negative selection	270144
12922137	12922160	3	-	26472758	KBM7	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	-0.07737848028676098	[231,214]	[95,102]	0	hSpCas9	negative selection	270145
12920553	12920576	3	+	26472758	KBM7	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	0.3771336749383236	[533,392]	[241,313]	4	hSpCas9	negative selection	270146
12936353	12936376	3	+	26472758	Raji	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.7460470559280018	[166]	[64]	7	hSpCas9	negative selection	461255
12920503	12920526	3	+	26472758	Raji	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	-0.15428403469628835	[210]	[43]	-1	hSpCas9	negative selection	461256
12941688	12941711	3	-	26472758	Raji	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	-0.5320267493699329	[80]	[12]	-4	hSpCas9	negative selection	461257
12936622	12936645	3	+	26472758	Raji	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.8964867528749809	[374]	[161]	7	hSpCas9	negative selection	461258
12936169	12936192	3	+	26472758	Raji	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.13276885379351328	[168]	[42]	1	hSpCas9	negative selection	461259
12935904	12935927	3	+	26472758	Raji	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	-0.8068865906005165	[97]	[12]	-6	hSpCas9	negative selection	461260
12924573	12924596	3	+	26472758	Raji	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.5277024447733931	[204]	[32]	-4	hSpCas9	negative selection	461261
12922154	12922177	3	-	26472758	Raji	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	0.31091692945873173	[65]	[18]	3	hSpCas9	negative selection	461262
12922137	12922160	3	-	26472758	Raji	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	-1.0201061997483163	[200]	[22]	-6	hSpCas9	negative selection	461263
12920553	12920576	3	+	26472758	Raji	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	-0.09957884539324258	[216]	[46]	-1	hSpCas9	negative selection	461264
12936353	12936376	3	+	26472758	K562	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	-0.6731191121415803	[288]	[152]	-4	hSpCas9	negative selection	652373
12920503	12920526	3	+	26472758	K562	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	0.665920890671422	[500]	[670]	5	hSpCas9	negative selection	652374
12941688	12941711	3	-	26472758	K562	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	0.6736700861649916	[100]	[135]	5	hSpCas9	negative selection	652375
12936622	12936645	3	+	26472758	K562	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.09830696816013607	[705]	[637]	0	hSpCas9	negative selection	652376
12936169	12936192	3	+	26472758	K562	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.03837097331395717	[499]	[410]	0	hSpCas9	negative selection	652377
12935904	12935927	3	+	26472758	K562	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	0.332887515528761	[252]	[268]	2	hSpCas9	negative selection	652378
12924573	12924596	3	+	26472758	K562	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	0.029567855342618105	[317]	[273]	0	hSpCas9	negative selection	652379
12922154	12922177	3	-	26472758	K562	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	0.27684020535882436	[87]	[89]	2	hSpCas9	negative selection	652380
12922137	12922160	3	-	26472758	K562	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	0.19064747122546605	[245]	[236]	1	hSpCas9	negative selection	652381
12920553	12920576	3	+	26472758	K562	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	-0.45729601931670727	[282]	[173]	-3	hSpCas9	negative selection	652382
12915614	12915637	3	+	26627737	DLD1	viability	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	0.9725827009268228	[210]	[154,136,100]	8	hSpCas9	negative selection	819485
12922157	12922180	3	-	26627737	DLD1	viability	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	1.6776585309281176	[0]	[0,0,0]	9	hSpCas9	negative selection	819486
12924610	12924633	3	-	26627737	DLD1	viability	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	0.28865033958141884	[993]	[526,470,175]	3	hSpCas9	negative selection	819487
12936169	12936192	3	+	26627737	DLD1	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.3188054803575211	[684]	[239,309,254]	3	hSpCas9	negative selection	819494
12941648	12941671	3	-	26627737	DLD1	viability	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.47989856565976996	[294]	[131,190,73]	5	hSpCas9	negative selection	819495
12967386	12967409	3	-	26627737	DLD1	viability	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	0.5024821933005172	[441]	[256,181,153]	5	hSpCas9	negative selection	819496
12915614	12915637	3	+	26627737	GBM cells	viability after 5 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	0.2437423718831267	[199]	[167,85]	4	hSpCas9	negative selection	901800
12922157	12922180	3	-	26627737	GBM cells	viability after 5 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	0.8989138748856851	[0]	[0,0]	9	hSpCas9	negative selection	901801
12924610	12924633	3	-	26627737	GBM cells	viability after 5 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	-0.10108612511431447	[489]	[218,270]	-1	hSpCas9	negative selection	901802
12936169	12936192	3	+	26627737	GBM cells	viability after 5 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.2541418964907014	[456]	[169,240]	-4	hSpCas9	negative selection	901809
12941648	12941671	3	-	26627737	GBM cells	viability after 5 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.10766661967971392	[166]	[78,113]	1	hSpCas9	negative selection	901810
12967386	12967409	3	-	26627737	GBM cells	viability after 5 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	-0.06972195420497926	[272]	[155,122]	-1	hSpCas9	negative selection	901811
12915614	12915637	3	+	26627737	GBM cells	viability after 13 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	0.7141591410822381	[199]	[150,199]	8	hSpCas9	negative selection	984115
12922157	12922180	3	-	26627737	GBM cells	viability after 13 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	0.8821031235784469	[0]	[0,0]	9	hSpCas9	negative selection	984116
12924610	12924633	3	-	26627737	GBM cells	viability after 13 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	-0.1984755227695606	[489]	[234,228]	-2	hSpCas9	negative selection	984117
12936169	12936192	3	+	26627737	GBM cells	viability after 13 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.0034771019275809945	[456]	[280,219]	0	hSpCas9	negative selection	984124
12941648	12941671	3	-	26627737	GBM cells	viability after 13 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.3678565945751435	[166]	[106,124]	5	hSpCas9	negative selection	984125
12967386	12967409	3	-	26627737	GBM cells	viability after 13 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	-0.025851583847710816	[272]	[166,127]	0	hSpCas9	negative selection	984126
12915614	12915637	3	+	26627737	GBM cells	viability after 21 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	0.937972370727735	[199]	[215,200]	8	hSpCas9	negative selection	1066430
12922157	12922180	3	-	26627737	GBM cells	viability after 21 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	0.8802332996156581	[0]	[0,0]	8	hSpCas9	negative selection	1066431
12924610	12924633	3	-	26627737	GBM cells	viability after 21 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	-0.6226105806319926	[489]	[186,159]	-5	hSpCas9	negative selection	1066432
12936169	12936192	3	+	26627737	GBM cells	viability after 21 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.1802982205068122	[456]	[239,199]	-2	hSpCas9	negative selection	1066439
12941648	12941671	3	-	26627737	GBM cells	viability after 21 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.25955689789400854	[166]	[105,110]	2	hSpCas9	negative selection	1066440
12967386	12967409	3	-	26627737	GBM cells	viability after 21 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	0.32723812120189133	[272]	[195,176]	3	hSpCas9	negative selection	1066441
12915614	12915637	3	+	26627737	RPE1	viability after 9 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	7.422410226536253	[3]	[216,211]	9	hSpCas9	negative selection	1148745
12922157	12922180	3	-	26627737	RPE1	viability after 9 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	1.6754465303148196	[0]	[0,0]	8	hSpCas9	negative selection	1148746
12924610	12924633	3	-	26627737	RPE1	viability after 9 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	-0.020945993544685626	[2205]	[550,847]	0	hSpCas9	negative selection	1148747
12936169	12936192	3	+	26627737	RPE1	viability after 9 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.012812179701129689	[1369]	[418,432]	0	hSpCas9	negative selection	1148754
12941648	12941671	3	-	26627737	RPE1	viability after 9 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	1.0505638233704555	[697]	[549,326]	6	hSpCas9	negative selection	1148755
12967386	12967409	3	-	26627737	RPE1	viability after 9 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	1.7350954344791485	[339]	[311,408]	8	hSpCas9	negative selection	1148756
12915614	12915637	3	+	26627737	RPE1	viability after 12 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	7.952013561548499	[3]	[252,279]	9	hSpCas9	negative selection	1231060
12922157	12922180	3	-	26627737	RPE1	viability after 12 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	1.8961114116731377	[0]	[0,0]	8	hSpCas9	negative selection	1231061
12924610	12924633	3	-	26627737	RPE1	viability after 12 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	-0.012765868496123156	[2205]	[653,516]	0	hSpCas9	negative selection	1231062
12936169	12936192	3	+	26627737	RPE1	viability after 12 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.5423222562210643	[1369]	[294,207]	-4	hSpCas9	negative selection	1231069
12941648	12941671	3	-	26627737	RPE1	viability after 12 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.8593886747565554	[697]	[449,223]	5	hSpCas9	negative selection	1231070
12967386	12967409	3	-	26627737	RPE1	viability after 12 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	1.7993441631327087	[339]	[281,355]	8	hSpCas9	negative selection	1231071
12915614	12915637	3	+	26627737	RPE1	viability after 15 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	6.92147153621704	[3]	[99,172]	9	hSpCas9	negative selection	1313375
12922157	12922180	3	-	26627737	RPE1	viability after 15 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	1.8217488738718943	[0]	[0,0]	8	hSpCas9	negative selection	1313376
12924610	12924633	3	-	26627737	RPE1	viability after 15 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	-0.2952487021014645	[2205]	[674,347]	-2	hSpCas9	negative selection	1313377
12936169	12936192	3	+	26627737	RPE1	viability after 15 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.14872649012021866	[1369]	[344,353]	-1	hSpCas9	negative selection	1313384
12941648	12941671	3	-	26627737	RPE1	viability after 15 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	1.3564201705535268	[697]	[754,264]	7	hSpCas9	negative selection	1313385
12967386	12967409	3	-	26627737	RPE1	viability after 15 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	1.7036901355883973	[339]	[240,382]	8	hSpCas9	negative selection	1313386
12915614	12915637	3	+	26627737	RPE1	viability after 18 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	7.836983197662918	[3]	[226,267]	9	hSpCas9	negative selection	1395690
12922157	12922180	3	-	26627737	RPE1	viability after 18 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	1.889668260100743	[0]	[0,0]	8	hSpCas9	negative selection	1395691
12924610	12924633	3	-	26627737	RPE1	viability after 18 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	-0.13227460153881876	[2205]	[693,381]	-1	hSpCas9	negative selection	1395692
12936169	12936192	3	+	26627737	RPE1	viability after 18 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.2728370431092676	[1369]	[422,180]	-2	hSpCas9	negative selection	1395699
12941648	12941671	3	-	26627737	RPE1	viability after 18 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	1.3003007599976792	[697]	[577,341]	7	hSpCas9	negative selection	1395700
12967386	12967409	3	-	26627737	RPE1	viability after 18 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	1.310405738854144	[339]	[243,209]	7	hSpCas9	negative selection	1395701
12915614	12915637	3	+	26627737	HeLa	viability after 8 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	-1.983793463552959	[294]	[111,1,2]	-9	hSpCas9	negative selection	1478005
12922157	12922180	3	-	26627737	HeLa	viability after 8 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	1.200473099817617	[0]	[0,0,0]	8	hSpCas9	negative selection	1478006
12924610	12924633	3	-	26627737	HeLa	viability after 8 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	0.9796801679233985	[610]	[479,378,691]	7	hSpCas9	negative selection	1478007
12936169	12936192	3	+	26627737	HeLa	viability after 8 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.21964917320470345	[669]	[540,288,239]	2	hSpCas9	negative selection	1478014
12941648	12941671	3	-	26627737	HeLa	viability after 8 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.020234504444492818	[338]	[264,130,82]	0	hSpCas9	negative selection	1478015
12967386	12967409	3	-	26627737	HeLa	viability after 8 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	0.3501196189802813	[340]	[169,215,177]	3	hSpCas9	negative selection	1478016
12915614	12915637	3	+	26627737	HeLa	viability after 12 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	-1.172064329182328	[294]	[40,43,77]	-8	hSpCas9	negative selection	1560320
12922157	12922180	3	-	26627737	HeLa	viability after 12 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	1.2748581272013126	[0]	[0,0,0]	8	hSpCas9	negative selection	1560321
12924610	12924633	3	-	26627737	HeLa	viability after 12 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	1.030870984582965	[610]	[412,532,596]	7	hSpCas9	negative selection	1560322
12936169	12936192	3	+	26627737	HeLa	viability after 12 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.06280381128052348	[669]	[343,177,358]	0	hSpCas9	negative selection	1560329
12941648	12941671	3	-	26627737	HeLa	viability after 12 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	-0.8903434466788097	[338]	[98,88,37]	-7	hSpCas9	negative selection	1560330
12967386	12967409	3	-	26627737	HeLa	viability after 12 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	0.37443701866122325	[340]	[125,261,149]	3	hSpCas9	negative selection	1560331
12915614	12915637	3	+	26627737	HeLa	viability after 15 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	-1.0359444612244897	[294]	[24,45,108]	-7	hSpCas9	negative selection	1642635
12922157	12922180	3	-	26627737	HeLa	viability after 15 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	1.2965331123080048	[0]	[0,0,0]	8	hSpCas9	negative selection	1642636
12924610	12924633	3	-	26627737	HeLa	viability after 15 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	1.2856755306628327	[610]	[771,572,460]	8	hSpCas9	negative selection	1642637
12936169	12936192	3	+	26627737	HeLa	viability after 15 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.4727620948398749	[669]	[213,207,164]	-4	hSpCas9	negative selection	1642644
12941648	12941671	3	-	26627737	HeLa	viability after 15 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.7117108584801591	[338]	[354,220,89]	5	hSpCas9	negative selection	1642645
12967386	12967409	3	-	26627737	HeLa	viability after 15 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	0.8205431633955866	[340]	[243,143,355]	6	hSpCas9	negative selection	1642646
12915614	12915637	3	+	26627737	HeLa	viability after 18 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	-0.9990082276557448	[294]	[18,38,108]	-7	hSpCas9	negative selection	1724950
12922157	12922180	3	-	26627737	HeLa	viability after 18 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	1.6067387639618715	[0]	[0,0,0]	9	hSpCas9	negative selection	1724951
12924610	12924633	3	-	26627737	HeLa	viability after 18 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	1.316706059292578	[610]	[547,468,460]	8	hSpCas9	negative selection	1724952
12936169	12936192	3	+	26627737	HeLa	viability after 18 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.4787008917755382	[669]	[134,180,164]	-4	hSpCas9	negative selection	1724959
12941648	12941671	3	-	26627737	HeLa	viability after 18 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.7652167864720573	[338]	[253,183,89]	6	hSpCas9	negative selection	1724960
12967386	12967409	3	-	26627737	HeLa	viability after 18 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	0.8117291122541399	[340]	[156,123,355]	6	hSpCas9	negative selection	1724961
12915614	12915637	3	+	26627737	HCT116	viability after 6 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	0.0011605001624996891	[232]	[84,9]	0	hSpCas9	negative selection	1807265
12922157	12922180	3	-	26627737	HCT116	viability after 6 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	2.6692602571875668	[0]	[0,0]	9	hSpCas9	negative selection	1807266
12924610	12924633	3	-	26627737	HCT116	viability after 6 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	1.2122276829236962	[1247]	[888,214]	6	hSpCas9	negative selection	1807267
12936169	12936192	3	+	26627737	HCT116	viability after 6 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-1.5637818483047041	[684]	[9,50]	-7	hSpCas9	negative selection	1807274
12941648	12941671	3	-	26627737	HCT116	viability after 6 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.6241442298650666	[674]	[33,234]	3	hSpCas9	negative selection	1807275
12967386	12967409	3	-	26627737	HCT116	viability after 6 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	0.9444721888172221	[360]	[270,19]	5	hSpCas9	negative selection	1807276
12915614	12915637	3	+	26627737	HCT116	viability after 8 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	-0.8607575852909074	[265]	[98,106,36]	-8	hSpCas9	negative selection	1889580
12922157	12922180	3	-	26627737	HCT116	viability after 8 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	0.8598070938499998	[0]	[0,0,0]	7	hSpCas9	negative selection	1889581
12924610	12924633	3	-	26627737	HCT116	viability after 8 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	-0.1382803904418508	[735]	[426,268,409]	-1	hSpCas9	negative selection	1889582
12936169	12936192	3	+	26627737	HCT116	viability after 8 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-1.0567674546837607	[493]	[150,117,123]	-8	hSpCas9	negative selection	1889589
12941648	12941671	3	-	26627737	HCT116	viability after 8 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	1.594382905949039	[102]	[178,222,112]	9	hSpCas9	negative selection	1889590
12967386	12967409	3	-	26627737	HCT116	viability after 8 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	-0.5122597074309869	[511]	[216,198,177]	-6	hSpCas9	negative selection	1889591
12915614	12915637	3	+	26627737	HCT116	viability after 9 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	1.3651666905036046	[232]	[171,150]	8	hSpCas9	negative selection	1971895
12922157	12922180	3	-	26627737	HCT116	viability after 9 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	1.9049898113534676	[0]	[0,0]	9	hSpCas9	negative selection	1971896
12924610	12924633	3	-	26627737	HCT116	viability after 9 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	0.0002923964160683745	[1247]	[358,312]	0	hSpCas9	negative selection	1971897
12936169	12936192	3	+	26627737	HCT116	viability after 9 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.5181549573279762	[684]	[395,155]	4	hSpCas9	negative selection	1971904
12941648	12941671	3	-	26627737	HCT116	viability after 9 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.16400713200321995	[674]	[316,110]	1	hSpCas9	negative selection	1971905
12967386	12967409	3	-	26627737	HCT116	viability after 9 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	1.8005622399129841	[360]	[270,386]	9	hSpCas9	negative selection	1971906
12915614	12915637	3	+	26627737	HCT116	viability after 12 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	-0.7622959688703793	[265]	[98,49,95]	-7	hSpCas9	negative selection	2054210
12922157	12922180	3	-	26627737	HCT116	viability after 12 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	0.9281650954308303	[0]	[0,0,0]	7	hSpCas9	negative selection	2054211
12924610	12924633	3	-	26627737	HCT116	viability after 12 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	-0.08422305476029623	[735]	[218,266,618]	-1	hSpCas9	negative selection	2054212
12936169	12936192	3	+	26627737	HCT116	viability after 12 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.1943584096229597	[493]	[232,303,144]	-2	hSpCas9	negative selection	2054219
12941648	12941671	3	-	26627737	HCT116	viability after 12 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.8408464207350834	[102]	[72,139,80]	7	hSpCas9	negative selection	2054220
12967386	12967409	3	-	26627737	HCT116	viability after 12 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	-0.6397620084965114	[511]	[136,204,179]	-6	hSpCas9	negative selection	2054221
12915614	12915637	3	+	26627737	HCT116	viability after 15 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	-0.2815120272388064	[265]	[154,131,93]	-3	hSpCas9	negative selection	2136525
12922157	12922180	3	-	26627737	HCT116	viability after 15 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	0.8001368291432343	[0]	[0,0,0]	7	hSpCas9	negative selection	2136526
12924610	12924633	3	-	26627737	HCT116	viability after 15 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	-0.23617935152773395	[735]	[167,249,631]	-2	hSpCas9	negative selection	2136527
12936169	12936192	3	+	26627737	HCT116	viability after 15 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.4545730943131959	[493]	[149,245,217]	-5	hSpCas9	negative selection	2136534
12941648	12941671	3	-	26627737	HCT116	viability after 15 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	1.0721559055639804	[102]	[180,156,42]	8	hSpCas9	negative selection	2136535
12967386	12967409	3	-	26627737	HCT116	viability after 15 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	-0.5825949567853047	[511]	[311,167,123]	-6	hSpCas9	negative selection	2136536
12915614	12915637	3	+	26627737	HCT116	viability after 18 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	-0.7064761314814929	[265]	[98,56,81]	-6	hSpCas9	negative selection	2218840
12922157	12922180	3	-	26627737	HCT116	viability after 18 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	1.0485523756554223	[0]	[0,0,0]	7	hSpCas9	negative selection	2218841
12924610	12924633	3	-	26627737	HCT116	viability after 18 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	-0.5337359594572677	[735]	[191,133,426]	-5	hSpCas9	negative selection	2218842
12936169	12936192	3	+	26627737	HCT116	viability after 18 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.4373252307135228	[493]	[203,225,91]	-4	hSpCas9	negative selection	2218849
12941648	12941671	3	-	26627737	HCT116	viability after 18 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.3940278510136248	[102]	[54,97,39]	3	hSpCas9	negative selection	2218850
12967386	12967409	3	-	26627737	HCT116	viability after 18 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	-0.7748780603205755	[511]	[168,185,72]	-6	hSpCas9	negative selection	2218851
12941730	12941753	3	-	24336569	HL60	viability	ACACGTCAGTGGGAGCCTATGGG	IQSEC1	ENSG00000144711	-0.09715282840318729	[2218]	[4389]	-1	hSpCas9	negative selection	2272016
12941740	12941763	3	-	24336569	HL60	viability	CACTACGAGCACACGTCAGTGGG	IQSEC1	ENSG00000144711	0.3617702904805996	[512]	[1394]	3	hSpCas9	negative selection	2272017
12941746	12941769	3	+	24336569	HL60	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	1.318332108286668	[338]	[1788]	8	hSpCas9	negative selection	2272018
12941753	12941776	3	+	24336569	HL60	viability	GCTCGTAGTGATCCGGGCTCAGG	IQSEC1	ENSG00000144711	0.20156721377060527	[202]	[493]	2	hSpCas9	negative selection	2272019
12941763	12941786	3	+	24336569	HL60	viability	ATCCGGGCTCAGGCTGGAACCGG	IQSEC1	ENSG00000144711	0.0059987406214427885	[55]	[118]	0	hSpCas9	negative selection	2272020
12941772	12941795	3	+	24336569	HL60	viability	CAGGCTGGAACCGGGCACCAAGG	IQSEC1	ENSG00000144711	-1.1263993320925452	[749]	[726]	-8	hSpCas9	negative selection	2272021
12941822	12941845	3	-	24336569	HL60	viability	CAGTGAGACTGGCACATCCCTGG	IQSEC1	ENSG00000144711	0.7030206721084492	[435]	[1501]	6	hSpCas9	negative selection	2272022
12941827	12941850	3	+	24336569	HL60	viability	GATGTGCCAGTCTCACTGCTGGG	IQSEC1	ENSG00000144711	0.6715294315042606	[366]	[1236]	6	hSpCas9	negative selection	2272023
12941852	12941875	3	-	24336569	HL60	viability	CCTCTGCAGCGTCGAGGGCGAGG	IQSEC1	ENSG00000144711	0.20622366984003349	[468]	[1144]	2	hSpCas9	negative selection	2272024
12941857	12941880	3	-	24336569	HL60	viability	TCTCTCCTCTGCAGCGTCGAGGG	IQSEC1	ENSG00000144711	3.562392089145828	[20]	[524]	9	hSpCas9	negative selection	2272025
12941730	12941753	3	-	24336569	KBM7	viability	ACACGTCAGTGGGAGCCTATGGG	IQSEC1	ENSG00000144711	0.10015726067848396	[915]	[2677]	0	hSpCas9	negative selection	2339193
12941740	12941763	3	-	24336569	KBM7	viability	CACTACGAGCACACGTCAGTGGG	IQSEC1	ENSG00000144711	0.6416742960399163	[520]	[2216]	6	hSpCas9	negative selection	2339194
12941746	12941769	3	+	24336569	KBM7	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.3879399406989329	[528]	[1887]	3	hSpCas9	negative selection	2339195
12941753	12941776	3	+	24336569	KBM7	viability	GCTCGTAGTGATCCGGGCTCAGG	IQSEC1	ENSG00000144711	0.43043027907250697	[110]	[407]	4	hSpCas9	negative selection	2339196
12941763	12941786	3	+	24336569	KBM7	viability	ATCCGGGCTCAGGCTGGAACCGG	IQSEC1	ENSG00000144711	0.2505939146202647	[97]	[317]	2	hSpCas9	negative selection	2339197
12941772	12941795	3	+	24336569	KBM7	viability	CAGGCTGGAACCGGGCACCAAGG	IQSEC1	ENSG00000144711	0.03841166074813246	[547]	[1534]	0	hSpCas9	negative selection	2339198
12941822	12941845	3	-	24336569	KBM7	viability	CAGTGAGACTGGCACATCCCTGG	IQSEC1	ENSG00000144711	-0.5453312277654504	[663]	[1240]	-4	hSpCas9	negative selection	2339199
12941827	12941850	3	+	24336569	KBM7	viability	GATGTGCCAGTCTCACTGCTGGG	IQSEC1	ENSG00000144711	0.8682256845400792	[424]	[2115]	7	hSpCas9	negative selection	2339200
12941852	12941875	3	-	24336569	KBM7	viability	CCTCTGCAGCGTCGAGGGCGAGG	IQSEC1	ENSG00000144711	-0.006466269935278102	[280]	[762]	0	hSpCas9	negative selection	2339201
12941857	12941880	3	-	24336569	KBM7	viability	TCTCTCCTCTGCAGCGTCGAGGG	IQSEC1	ENSG00000144711	-0.7809020460363569	[285]	[453]	-5	hSpCas9	negative selection	2339202
12967815	12967838	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGAGACTGCACGGAGCGTGTGG	IQSEC1	ENSG00000144711	1.2673861466556169	[34,98]	[5,67]	5	dCas9-VP64	positive selection	2445017
12967861	12967884	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTTCTTCCGCGGCGCCGTGTGG	IQSEC1	ENSG00000144711	-1.4608841041392404	[48,41]	[4,0]	-8	dCas9-VP64	positive selection	2445018
12967838	12967861	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAAGAGAGCACAGGAGGCGTGG	IQSEC1	ENSG00000144711	3.839374590412263	[76,38]	[57,315]	9	dCas9-VP64	positive selection	2445019
12918586	12918609	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGAGGATCACTTGAGGCCAAG	IQSEC1	ENSG00000144711	3.7396651611807004	[3,72]	[11,226]	9	dCas9-VP64	positive selection	2451753
13058206	13058229	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGTTGCAGTGAGCCGAGATGG	IQSEC1	ENSG00000144711	0.6330757747468561	[50,16]	[8,13]	2	dCas9-VP64	positive selection	2476982
12967815	12967838	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGAGACTGCACGGAGCGTGTGG	IQSEC1	ENSG00000144711	-1.036474126442788	[187,7]	[25,5]	-8	dCas9-VP64	positive selection	2540272
12967861	12967884	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTTCTTCCGCGGCGCCGTGTGG	IQSEC1	ENSG00000144711	0.36691751843935416	[34,104]	[19,36]	3	dCas9-VP64	positive selection	2540273
12967838	12967861	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAAGAGAGCACAGGAGGCGTGG	IQSEC1	ENSG00000144711	0.4074617263712319	[27,98]	[39,14]	3	dCas9-VP64	positive selection	2540274
12918586	12918609	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGAGGATCACTTGAGGCCAAG	IQSEC1	ENSG00000144711	0.5989374680558959	[87,40]	[52,11]	4	dCas9-VP64	positive selection	2547008
13058206	13058229	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGTTGCAGTGAGCCGAGATGG	IQSEC1	ENSG00000144711	0.34517561365305327	[29,16]	[7,9]	2	dCas9-VP64	positive selection	2572237
12967387	12967410	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGGAGCTAGAGCTTGACAGCGG	IQSEC1	ENSG00000144711	0.18258437728289495	[4,4]	[4,4]	4	hSpCas9	positive selection	2995891
12936405	12936428	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGAGGTCACCACACTCAGGGG	IQSEC1	ENSG00000144711	0.4527473112849752	[3,3]	[2,5]	8	hSpCas9	positive selection	2995892
12935905	12935928	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	0.22567879401697405	[3,4]	[2,4]	5	hSpCas9	positive selection	2995893
12935855	12935878	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAGTGACCCCCGCTCCGAGCGG	IQSEC1	ENSG00000144711	-0.16774183529944217	[3,2]	[2,1]	-2	hSpCas9	positive selection	2995894
12967387	12967410	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGGAGCTAGAGCTTGACAGCGG	IQSEC1	ENSG00000144711	0.12306058849160162	[4,4]	[4,2]	2	hSpCas9	positive selection	3063749
12936405	12936428	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGAGGTCACCACACTCAGGGG	IQSEC1	ENSG00000144711	-0.4728087487193336	[3,3]	[2,0]	-6	hSpCas9	positive selection	3063750
12935905	12935928	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	-0.3243501844142454	[3,3]	[3,0]	-5	hSpCas9	positive selection	3063751
12935855	12935878	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAGTGACCCCCGCTCCGAGCGG	IQSEC1	ENSG00000144711	0.3696751864987825	[3,3]	[3,2]	6	hSpCas9	positive selection	3063752
12936067	12936090		-	24336571	A375	resistance to PLX after 7 days	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.14870818136041503	[8,9]	[6,9]	-5	hSpCas9	positive selection	3121520
12941691	12941714		-	24336571	A375	resistance to PLX after 7 days	CGGGGCAACAGCAGCGCACGCGG	IQSEC1	ENSG00000144711	0.12060284749640988	[11,13]	[12,14]	4	hSpCas9	positive selection	3121521
12935978	12936001		-	24336571	A375	resistance to PLX after 7 days	CTGACACGGACACGAGCTGCCGG	IQSEC1	ENSG00000144711	0.008396882582439646	[16,23]	[18,20]	0	hSpCas9	positive selection	3121522
12941746	12941769		+	24336571	A375	resistance to PLX after 7 days	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.186887913223941	[12,10]	[12,8]	-6	hSpCas9	positive selection	3121523
12941741	12941764		-	24336571	A375	resistance to PLX after 7 days	TCACTACGAGCACACGTCAGTGG	IQSEC1	ENSG00000144711	0.003484216604362267	[22,21]	[23,19]	0	hSpCas9	positive selection	3121524
12935655	12935678		-	24336571	A375	resistance to PLX after 7 days	TCTGAGTCGGACTACTCAGACGG	IQSEC1	ENSG00000144711	-0.25200548516142807	[7,9]	[5,7]	-7	hSpCas9	positive selection	3121525
12936067	12936090		-	24336571	A375	resistance to PLX after 14 days	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	0.17462174257622876	[10,8]	[3,4]	1	hSpCas9	positive selection	3179313
12941691	12941714		-	24336571	A375	resistance to PLX after 14 days	CGGGGCAACAGCAGCGCACGCGG	IQSEC1	ENSG00000144711	-0.4735817557381218	[8,18]	[3,3]	-5	hSpCas9	positive selection	3179314
12935978	12936001		-	24336571	A375	resistance to PLX after 14 days	CTGACACGGACACGAGCTGCCGG	IQSEC1	ENSG00000144711	-0.05615324415160128	[16,18]	[7,6]	0	hSpCas9	positive selection	3179315
12941746	12941769		+	24336571	A375	resistance to PLX after 14 days	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.16308710923378655	[9,8]	[3,3]	-2	hSpCas9	positive selection	3179316
12941741	12941764		-	24336571	A375	resistance to PLX after 14 days	TCACTACGAGCACACGTCAGTGG	IQSEC1	ENSG00000144711	-0.9838675676681892	[24,21]	[4,4]	-9	hSpCas9	positive selection	3179317
12935655	12935678		-	24336571	A375	resistance to PLX after 14 days	TCTGAGTCGGACTACTCAGACGG	IQSEC1	ENSG00000144711	0.17067366937757011	[5,6]	[2,2]	1	hSpCas9	positive selection	3179318
12936067	12936090		-	24336571	A375	viability after 7 days	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	0.03270815628273549	[9]	[8,9]	0	hSpCas9	negative selection	3237106
12941691	12941714		-	24336571	A375	viability after 7 days	CGGGGCAACAGCAGCGCACGCGG	IQSEC1	ENSG00000144711	7.524725913336631e-05	[12]	[11,13]	0	hSpCas9	negative selection	3237107
12935978	12936001		-	24336571	A375	viability after 7 days	CTGACACGGACACGAGCTGCCGG	IQSEC1	ENSG00000144711	0.6054870354978769	[13]	[16,23]	8	hSpCas9	negative selection	3237108
12941746	12941769		+	24336571	A375	viability after 7 days	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.7625864737827487	[6]	[12,10]	9	hSpCas9	negative selection	3237109
12941741	12941764		-	24336571	A375	viability after 7 days	TCACTACGAGCACACGTCAGTGG	IQSEC1	ENSG00000144711	1.4877507638761913	[7]	[22,21]	9	hSpCas9	negative selection	3237110
12935655	12935678		-	24336571	A375	viability after 7 days	TCTGAGTCGGACTACTCAGACGG	IQSEC1	ENSG00000144711	0.0022353611045633492	[8]	[7,9]	0	hSpCas9	negative selection	3237111
12936067	12936090		-	24336571	A375	viability after 14 days	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	0.09254679567630841	[9]	[10,8]	1	hSpCas9	negative selection	3294899
12941691	12941714		-	24336571	A375	viability after 14 days	CGGGGCAACAGCAGCGCACGCGG	IQSEC1	ENSG00000144711	0.16779714809220686	[12]	[8,18]	2	hSpCas9	negative selection	3294900
12935978	12936001		-	24336571	A375	viability after 14 days	CTGACACGGACACGAGCTGCCGG	IQSEC1	ENSG00000144711	0.44411524977499905	[13]	[16,18]	5	hSpCas9	negative selection	3294901
12941746	12941769		+	24336571	A375	viability after 14 days	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.4241207474886509	[6]	[9,8]	5	hSpCas9	negative selection	3294902
12941741	12941764		-	24336571	A375	viability after 14 days	TCACTACGAGCACACGTCAGTGG	IQSEC1	ENSG00000144711	1.585172911616059	[7]	[24,21]	9	hSpCas9	negative selection	3294903
12935655	12935678		-	24336571	A375	viability after 14 days	TCTGAGTCGGACTACTCAGACGG	IQSEC1	ENSG00000144711	-0.38618948616042437	[8]	[5,6]	-4	hSpCas9	negative selection	3294904
12936646	12936669	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	2.1280431945008687	[34,34]	[0,0]	7	hSpCas9	positive selection	3374574
12936067	12936090	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	0.4371472490306473	[112,112]	[0,0]	2	hSpCas9	positive selection	3374575
12941718	12941741	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.40088527130595975	[201,201]	[0,0]	-3	hSpCas9	positive selection	3374576
12967387	12967410	3	-	26780180	HT29	viability (Avana library 4 designs)	CTGGAGCTAGAGCTTGACAGCGG	IQSEC1	ENSG00000144711	0.831988029669132	[]	[]	3	hSpCas9	negative selection	3433280
12936404	12936427	3	+	26780180	HT29	viability (Avana library 4 designs)	GCTGAGGTCACCACACTCAGGGG	IQSEC1	ENSG00000144711	0.131691825458816	[]	[]	0	hSpCas9	negative selection	3433281
12935904	12935927	3	+	26780180	HT29	viability (Avana library 4 designs)	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	1.21139771885832	[]	[]	5	hSpCas9	negative selection	3433282
12935854	12935877	3	+	26780180	HT29	viability (Avana library 4 designs)	TGAGTGACCCCCGCTCCGAGCGG	IQSEC1	ENSG00000144711	1.13090789288956	[]	[]	4	hSpCas9	negative selection	3433283
12967387	12967410	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGGAGCTAGAGCTTGACAGCGG	IQSEC1	ENSG00000144711	3.93534314810164	[]	[]	6	hSpCas9	negative selection	3519813
12935904	12935927	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	2.79205316219669	[]	[]	4	hSpCas9	negative selection	3519814
12935854	12935877	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGTGACCCCCGCTCCGAGCGG	IQSEC1	ENSG00000144711	-1.16517077707796	[]	[]	-1	hSpCas9	negative selection	3519815
12936404	12936427	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGAGGTCACCACACTCAGGGG	IQSEC1	ENSG00000144711	0.696293691309939	[]	[]	1	hSpCas9	negative selection	3519816
12936628	12936651	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGCGGCCCGCACCATCCAGACGG	IQSEC1	ENSG00000144711	0.0669039028453355	[]	[]	0	hSpCas9	negative selection	3519817
12936544	12936567	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	3.87911119120034	[]	[]	6	hSpCas9	negative selection	3519818
12967387	12967410	3	-	26780180	A375	viability (Avana lentiGuide)	CTGGAGCTAGAGCTTGACAGCGG	IQSEC1	ENSG00000144711	0.476851250789665	[]	[]	0	hSpCas9	negative selection	3628472
12935904	12935927	3	+	26780180	A375	viability (Avana lentiGuide)	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	5.29251543091959	[]	[]	5	hSpCas9	negative selection	3628473
12935854	12935877	3	+	26780180	A375	viability (Avana lentiGuide)	TGAGTGACCCCCGCTCCGAGCGG	IQSEC1	ENSG00000144711	-2.69679260480626	[]	[]	-5	hSpCas9	negative selection	3628474
12936404	12936427	3	+	26780180	A375	viability (Avana lentiGuide)	GCTGAGGTCACCACACTCAGGGG	IQSEC1	ENSG00000144711	-3.67060659207931	[]	[]	-6	hSpCas9	negative selection	3628475
12936628	12936651	3	-	26780180	A375	viability (Avana lentiGuide)	TGCGGCCCGCACCATCCAGACGG	IQSEC1	ENSG00000144711	0.444570044575925	[]	[]	0	hSpCas9	negative selection	3628476
12936544	12936567	3	+	26780180	A375	viability (Avana lentiGuide)	GCACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	2.44740844981413	[]	[]	2	hSpCas9	negative selection	3628477
12967387	12967410	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGGAGCTAGAGCTTGACAGCGG	IQSEC1	ENSG00000144711	0.14311686473378635	[5]	[6,5]	4	hSpCas9	positive selection	3737131
12935904	12935927	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	0.029465778533923112	[5]	[5,4]	0	hSpCas9	positive selection	3737132
12935854	12935877	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGTGACCCCCGCTCCGAGCGG	IQSEC1	ENSG00000144711	-0.07054249784311234	[3]	[3,3]	-1	hSpCas9	positive selection	3737133
12936404	12936427	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGAGGTCACCACACTCAGGGG	IQSEC1	ENSG00000144711	-0.015907332309744848	[5]	[5,4]	0	hSpCas9	positive selection	3737134
12936628	12936651	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCGGCCCGCACCATCCAGACGG	IQSEC1	ENSG00000144711	-0.06598101565980283	[4]	[4,2]	-1	hSpCas9	positive selection	3737135
12936544	12936567	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.15724218490591907	[4]	[4,4]	4	hSpCas9	positive selection	3737136
12967387	12967410	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGGAGCTAGAGCTTGACAGCGG	IQSEC1	ENSG00000144711	-0.12240814748427371	[6]	[3,6]	-2	hSpCas9	positive selection	3845738
12935904	12935927	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	-0.09565451590097451	[5]	[5,2]	-1	hSpCas9	positive selection	3845739
12935854	12935877	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGTGACCCCCGCTCCGAGCGG	IQSEC1	ENSG00000144711	0.3256865088894213	[4]	[3,5]	8	hSpCas9	positive selection	3845740
12936404	12936427	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGAGGTCACCACACTCAGGGG	IQSEC1	ENSG00000144711	0.21522864783347162	[4]	[4,5]	5	hSpCas9	positive selection	3845741
12936628	12936651	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCGGCCCGCACCATCCAGACGG	IQSEC1	ENSG00000144711	0.21082666808015382	[5]	[4,4]	5	hSpCas9	positive selection	3845742
12936544	12936567	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.2646534171111403	[5]	[5,5]	7	hSpCas9	positive selection	3845743
12936067	12936090	3	-	26780180	A375	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	0.961196119006076	[]	[]	4	hSpCas9	negative selection	3951754
12924573	12924596	3	+	26780180	A375	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	0.746458565096657	[]	[]	2	hSpCas9	negative selection	3951755
12941746	12941769	3	+	26780180	A375	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	1.44691638948932	[]	[]	8	hSpCas9	negative selection	3951756
12941718	12941741	3	-	26780180	A375	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	0.999714133418617	[]	[]	4	hSpCas9	negative selection	3951757
12936646	12936669	3	-	26780180	A375	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.857664588889802	[]	[]	3	hSpCas9	negative selection	3951758
12924680	12924703	3	-	26780180	A375	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	1.19282984593128	[]	[]	6	hSpCas9	negative selection	3951759
12936067	12936090	3	-	26780180	HT29	viability (GeCKOv2 library)	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	1.15750046591135	[]	[]	5	hSpCas9	negative selection	4059720
12924573	12924596	3	+	26780180	HT29	viability (GeCKOv2 library)	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	0.732325256068677	[]	[]	3	hSpCas9	negative selection	4059721
12941746	12941769	3	+	26780180	HT29	viability (GeCKOv2 library)	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	2.17602381738915	[]	[]	9	hSpCas9	negative selection	4059722
12941718	12941741	3	-	26780180	HT29	viability (GeCKOv2 library)	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	0.917988552586155	[]	[]	4	hSpCas9	negative selection	4059723
12936646	12936669	3	-	26780180	HT29	viability (GeCKOv2 library)	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.771366482161163	[]	[]	3	hSpCas9	negative selection	4059724
12924680	12924703	3	-	26780180	HT29	viability (GeCKOv2 library)	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.450593293356033	[]	[]	1	hSpCas9	negative selection	4059725
12936067	12936090	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	0.06253875294738834	[3]	[2,2]	1	hSpCas9	positive selection	4145214
12941691	12941714	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGGGCAACAGCAGCGCACGCGG	IQSEC1	ENSG00000144711	-0.08174460699849581	[3]	[2,1]	-2	hSpCas9	positive selection	4145215
12935978	12936001	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGACACGGACACGAGCTGCCGG	IQSEC1	ENSG00000144711	0.013847180755360927	[4]	[2,2]	0	hSpCas9	positive selection	4145216
12941746	12941769	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.3504874174530234	[3]	[1,1]	-7	hSpCas9	positive selection	4145217
12941741	12941764	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCACTACGAGCACACGTCAGTGG	IQSEC1	ENSG00000144711	-0.10706324602196637	[4]	[2,2]	-3	hSpCas9	positive selection	4145218
12935655	12935678	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTGAGTCGGACTACTCAGACGG	IQSEC1	ENSG00000144711	0.40040634263855834	[3]	[3,1]	8	hSpCas9	positive selection	4145219
12936067	12936090	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	0.3510455394021028	[2]	[2,3,0,0]	2	hSpCas9	positive selection	4209236
12941691	12941714	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGGGCAACAGCAGCGCACGCGG	IQSEC1	ENSG00000144711	0.8469998541031933	[4]	[4,0,1,3]	5	hSpCas9	positive selection	4209237
12935978	12936001	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGACACGGACACGAGCTGCCGG	IQSEC1	ENSG00000144711	-0.0787689905117692	[3]	[0,3,0,0]	-1	hSpCas9	positive selection	4209238
12941746	12941769	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.3666777208327653	[3]	[2,0,0,0]	-5	hSpCas9	positive selection	4209239
12941741	12941764	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCACTACGAGCACACGTCAGTGG	IQSEC1	ENSG00000144711	0.046951603838644634	[4]	[0,2,4,0]	0	hSpCas9	positive selection	4209240
12935655	12935678	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTGAGTCGGACTACTCAGACGG	IQSEC1	ENSG00000144711	1.2615248102425265	[0]	[0,3,0,0]	9	hSpCas9	positive selection	4209241
12924680	12924703	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.07425338922970276	[3]	[3,2]	1	hSpCas9	positive selection	4277220
12924573	12924596	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.2516925403764501	[4]	[3,1]	-5	hSpCas9	positive selection	4277221
12941746	12941769	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.4860281158265148	[3]	[2,1]	-8	hSpCas9	positive selection	4277222
12936646	12936669	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.059804728004037244	[1]	[1,1]	1	hSpCas9	positive selection	4341476
12936067	12936090	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	0.06903122518418034	[2]	[2,1]	1	hSpCas9	positive selection	4341477
12941718	12941741	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	0.11475485238363503	[3]	[2,2]	2	hSpCas9	positive selection	4341478
12935864	12935886	3	+	27760321	OCIAML3	viability	CCGCTCCGAGCGGTCACTAAGG	IQSEC1	ENSG00000144711	0.12932623699167511	[299,273]	[224,271]	1	hSpCas9	negative selection	4410205
12936060	12936082	3	+	27760321	OCIAML3	viability	CGCAGGTCCGACTCGGTGCTGG	IQSEC1	ENSG00000144711	0.27533463181686657	[1341,978]	[899,1332]	3	hSpCas9	negative selection	4410206
12936354	12936376	3	+	27760321	OCIAML3	viability	GCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	-0.4823887417279526	[565,459]	[309,253]	-5	hSpCas9	negative selection	4410207
12936545	12936567	3	+	27760321	OCIAML3	viability	CACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.013897911644235678	[576,452]	[314,519]	0	hSpCas9	negative selection	4410208
12941748	12941770	3	+	27760321	OCIAML3	viability	CGTGTGCTCGTAGTGATCCGGG	IQSEC1	ENSG00000144711	0.09766012973372373	[696,698]	[576,597]	1	hSpCas9	negative selection	4410209
12935864	12935886	3	+	27760321	OCIAML2	viability	CCGCTCCGAGCGGTCACTAAGG	IQSEC1	ENSG00000144711	0.5144844772620136	[299,273]	[277,401]	7	hSpCas9	negative selection	4493668
12936060	12936082	3	+	27760321	OCIAML2	viability	CGCAGGTCCGACTCGGTGCTGG	IQSEC1	ENSG00000144711	0.27760506153944897	[1341,978]	[900,1424]	3	hSpCas9	negative selection	4493669
12936354	12936376	3	+	27760321	OCIAML2	viability	GCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.4588061866053469	[565,459]	[465,700]	6	hSpCas9	negative selection	4493670
12936545	12936567	3	+	27760321	OCIAML2	viability	CACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.37009219781937885	[576,452]	[445,651]	5	hSpCas9	negative selection	4493671
12941748	12941770	3	+	27760321	OCIAML2	viability	CGTGTGCTCGTAGTGATCCGGG	IQSEC1	ENSG00000144711	-0.5475423848802711	[696,698]	[293,510]	-6	hSpCas9	negative selection	4493672
12935864	12935886	3	+	27760321	MV411	viability	CCGCTCCGAGCGGTCACTAAGG	IQSEC1	ENSG00000144711	-0.8980288916361912	[299,273]	[85,124]	-6	hSpCas9	negative selection	4577131
12936060	12936082	3	+	27760321	MV411	viability	CGCAGGTCCGACTCGGTGCTGG	IQSEC1	ENSG00000144711	0.13516766651032253	[1341,978]	[830,835]	0	hSpCas9	negative selection	4577132
12936354	12936376	3	+	27760321	MV411	viability	GCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.0848641271643149	[565,459]	[84,765]	0	hSpCas9	negative selection	4577133
12936545	12936567	3	+	27760321	MV411	viability	CACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.5522498517860869	[576,452]	[562,392]	4	hSpCas9	negative selection	4577134
12941748	12941770	3	+	27760321	MV411	viability	CGTGTGCTCGTAGTGATCCGGG	IQSEC1	ENSG00000144711	0.2576502394867839	[696,698]	[729,285]	1	hSpCas9	negative selection	4577135
12935864	12935886	3	+	27760321	HL60	viability	CCGCTCCGAGCGGTCACTAAGG	IQSEC1	ENSG00000144711	-0.054779131153150584	[299,273]	[162,291]	0	hSpCas9	negative selection	4660594
12936060	12936082	3	+	27760321	HL60	viability	CGCAGGTCCGACTCGGTGCTGG	IQSEC1	ENSG00000144711	0.37510393491811844	[1341,978]	[1042,1402]	4	hSpCas9	negative selection	4660595
12936354	12936376	3	+	27760321	HL60	viability	GCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	-0.16681584474945516	[565,459]	[316,428]	-2	hSpCas9	negative selection	4660596
12936545	12936567	3	+	27760321	HL60	viability	CACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.46482451408007974	[576,452]	[635,513]	5	hSpCas9	negative selection	4660597
12941748	12941770	3	+	27760321	HL60	viability	CGTGTGCTCGTAGTGATCCGGG	IQSEC1	ENSG00000144711	-0.9682217263517043	[696,698]	[256,329]	-7	hSpCas9	negative selection	4660598
12935864	12935886	3	+	27760321	HT1080	viability	CCGCTCCGAGCGGTCACTAAGG	IQSEC1	ENSG00000144711	2.2187065161966544	[273,213]	[472,429]	9	hSpCas9	negative selection	4744057
12936060	12936082	3	+	27760321	HT1080	viability	CGCAGGTCCGACTCGGTGCTGG	IQSEC1	ENSG00000144711	1.0918978364850114	[978,763]	[729,750]	6	hSpCas9	negative selection	4744058
12936354	12936376	3	+	27760321	HT1080	viability	GCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.32242747635344915	[459,358]	[150,261]	1	hSpCas9	negative selection	4744059
12936545	12936567	3	+	27760321	HT1080	viability	CACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	1.1868136135414875	[452,353]	[617,89]	6	hSpCas9	negative selection	4744060
12941748	12941770	3	+	27760321	HT1080	viability	CGTGTGCTCGTAGTGATCCGGG	IQSEC1	ENSG00000144711	0.3598330722187828	[698,545]	[312,323]	1	hSpCas9	negative selection	4744061
12935864	12935886	3	+	27760321	HT29	viability after 7 days	CCGCTCCGAGCGGTCACTAAGG	IQSEC1	ENSG00000144711	0.18407554454633762	[273,213]	[584,307,212]	3	hSpCas9	negative selection	4827520
12936060	12936082	3	+	27760321	HT29	viability after 7 days	CGCAGGTCCGACTCGGTGCTGG	IQSEC1	ENSG00000144711	0.7378493688657555	[978,763]	[2138,1896,1613]	9	hSpCas9	negative selection	4827521
12936354	12936376	3	+	27760321	HT29	viability after 7 days	GCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.3000805206792215	[459,358]	[553,717,657]	4	hSpCas9	negative selection	4827522
12936545	12936567	3	+	27760321	HT29	viability after 7 days	CACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.4057493569566777	[452,353]	[730,800,539]	6	hSpCas9	negative selection	4827523
12941748	12941770	3	+	27760321	HT29	viability after 7 days	CGTGTGCTCGTAGTGATCCGGG	IQSEC1	ENSG00000144711	-0.9781206262886819	[698,545]	[504,402,326]	-8	hSpCas9	negative selection	4827524
12935864	12935886	3	+	27760321	HT29	viability after 25 days	CCGCTCCGAGCGGTCACTAAGG	IQSEC1	ENSG00000144711	0.5275234623021922	[273,213]	[386,289,543]	6	hSpCas9	negative selection	4910983
12936060	12936082	3	+	27760321	HT29	viability after 25 days	CGCAGGTCCGACTCGGTGCTGG	IQSEC1	ENSG00000144711	0.9746234128584099	[978,763]	[1860,2320,1661]	9	hSpCas9	negative selection	4910984
12936354	12936376	3	+	27760321	HT29	viability after 25 days	GCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.7621260085922472	[459,358]	[934,736,687]	8	hSpCas9	negative selection	4910985
12936545	12936567	3	+	27760321	HT29	viability after 25 days	CACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.4289811143936929	[452,353]	[519,795,543]	4	hSpCas9	negative selection	4910986
12941748	12941770	3	+	27760321	HT29	viability after 25 days	CGTGTGCTCGTAGTGATCCGGG	IQSEC1	ENSG00000144711	-0.8539139463793088	[698,545]	[484,334,349]	-6	hSpCas9	negative selection	4910987
12935864	12935886	3	+	27760321	HT29	viability after 22 days	CCGCTCCGAGCGGTCACTAAGG	IQSEC1	ENSG00000144711	0.13675360855902124	[273,213]	[329,274,324]	1	hSpCas9	negative selection	4994446
12936060	12936082	3	+	27760321	HT29	viability after 22 days	CGCAGGTCCGACTCGGTGCTGG	IQSEC1	ENSG00000144711	1.039526096213911	[978,763]	[1976,2512,1721]	9	hSpCas9	negative selection	4994447
12936354	12936376	3	+	27760321	HT29	viability after 22 days	GCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.2208028342831126	[459,358]	[494,566,594]	2	hSpCas9	negative selection	4994448
12936545	12936567	3	+	27760321	HT29	viability after 22 days	CACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.6593208083132274	[452,353]	[680,874,654]	7	hSpCas9	negative selection	4994449
12941748	12941770	3	+	27760321	HT29	viability after 22 days	CGTGTGCTCGTAGTGATCCGGG	IQSEC1	ENSG00000144711	-0.6244554941936089	[698,545]	[407,428,565]	-5	hSpCas9	negative selection	4994450
12935864	12935886	3	+	27760321	HT29	viability after 19 days	CCGCTCCGAGCGGTCACTAAGG	IQSEC1	ENSG00000144711	0.06997691856783711	[273,213]	[381,160,342]	0	hSpCas9	negative selection	5077909
12936060	12936082	3	+	27760321	HT29	viability after 19 days	CGCAGGTCCGACTCGGTGCTGG	IQSEC1	ENSG00000144711	0.8194296140225283	[978,763]	[2187,1817,1330]	8	hSpCas9	negative selection	5077910
12936354	12936376	3	+	27760321	HT29	viability after 19 days	GCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.5834339424440317	[459,358]	[670,498,922]	6	hSpCas9	negative selection	5077911
12936545	12936567	3	+	27760321	HT29	viability after 19 days	CACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.8328695284387363	[452,353]	[1078,738,679]	8	hSpCas9	negative selection	5077912
12941748	12941770	3	+	27760321	HT29	viability after 19 days	CGTGTGCTCGTAGTGATCCGGG	IQSEC1	ENSG00000144711	-1.0921274869489128	[698,545]	[437,305,270]	-6	hSpCas9	negative selection	5077913
12935864	12935886	3	+	27760321	HT29	viability after 16 days	CCGCTCCGAGCGGTCACTAAGG	IQSEC1	ENSG00000144711	0.578583989347971	[273,213]	[404,321,497]	6	hSpCas9	negative selection	5161372
12936060	12936082	3	+	27760321	HT29	viability after 16 days	CGCAGGTCCGACTCGGTGCTGG	IQSEC1	ENSG00000144711	0.852342260385917	[978,763]	[2584,1479,1300]	8	hSpCas9	negative selection	5161373
12936354	12936376	3	+	27760321	HT29	viability after 16 days	GCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.5704004043775143	[459,358]	[820,685,546]	6	hSpCas9	negative selection	5161374
12936545	12936567	3	+	27760321	HT29	viability after 16 days	CACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.4909339611744453	[452,353]	[760,568,586]	5	hSpCas9	negative selection	5161375
12941748	12941770	3	+	27760321	HT29	viability after 16 days	CGTGTGCTCGTAGTGATCCGGG	IQSEC1	ENSG00000144711	-0.976187851695318	[698,545]	[573,194,317]	-7	hSpCas9	negative selection	5161376
12935864	12935886	3	+	27760321	HT29	viability after 13 days	CCGCTCCGAGCGGTCACTAAGG	IQSEC1	ENSG00000144711	0.39780763547800735	[273,213]	[397,266,448]	5	hSpCas9	negative selection	5244835
12936060	12936082	3	+	27760321	HT29	viability after 13 days	CGCAGGTCCGACTCGGTGCTGG	IQSEC1	ENSG00000144711	1.0787439540238992	[978,763]	[2295,2507,1632]	9	hSpCas9	negative selection	5244836
12936354	12936376	3	+	27760321	HT29	viability after 13 days	GCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	-0.03469380337256836	[459,358]	[531,376,480]	0	hSpCas9	negative selection	5244837
12936545	12936567	3	+	27760321	HT29	viability after 13 days	CACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.33208301204820745	[452,353]	[616,667,488]	4	hSpCas9	negative selection	5244838
12941748	12941770	3	+	27760321	HT29	viability after 13 days	CGTGTGCTCGTAGTGATCCGGG	IQSEC1	ENSG00000144711	-0.9190612938334454	[698,545]	[429,356,359]	-7	hSpCas9	negative selection	5244839
12935864	12935886	3	+	27760321	HT29	viability after 10 days	CCGCTCCGAGCGGTCACTAAGG	IQSEC1	ENSG00000144711	0.2586267324296537	[273,213]	[314,318,455]	3	hSpCas9	negative selection	5328298
12936060	12936082	3	+	27760321	HT29	viability after 10 days	CGCAGGTCCGACTCGGTGCTGG	IQSEC1	ENSG00000144711	0.6004520939215878	[978,763]	[2072,1478,1397]	7	hSpCas9	negative selection	5328299
12936354	12936376	3	+	27760321	HT29	viability after 10 days	GCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.33449195768683815	[459,358]	[592,487,843]	4	hSpCas9	negative selection	5328300
12936545	12936567	3	+	27760321	HT29	viability after 10 days	CACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.514092331232425	[452,353]	[754,774,631]	7	hSpCas9	negative selection	5328301
12941748	12941770	3	+	27760321	HT29	viability after 10 days	CGTGTGCTCGTAGTGATCCGGG	IQSEC1	ENSG00000144711	-1.026312436780929	[698,545]	[411,492,245]	-8	hSpCas9	negative selection	5328302
12935864	12935886	3	+	27760321	MOLM13	viability	CCGCTCCGAGCGGTCACTAAGG	IQSEC1	ENSG00000144711	0.7738055467116663	[299,273]	[434,141]	5	hSpCas9	negative selection	5411761
12936060	12936082	3	+	27760321	MOLM13	viability	CGCAGGTCCGACTCGGTGCTGG	IQSEC1	ENSG00000144711	0.7844759172247291	[1341,978]	[1163,1076]	5	hSpCas9	negative selection	5411762
12936354	12936376	3	+	27760321	MOLM13	viability	GCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.9216335482530496	[565,459]	[781,343]	6	hSpCas9	negative selection	5411763
12936545	12936567	3	+	27760321	MOLM13	viability	CACAATCCGGCGTGACATGCGG	IQSEC1	ENSG00000144711	0.39284286653239064	[576,452]	[506,269]	2	hSpCas9	negative selection	5411764
12941748	12941770	3	+	27760321	MOLM13	viability	CGTGTGCTCGTAGTGATCCGGG	IQSEC1	ENSG00000144711	0.06705099956599714	[696,698]	[259,544]	0	hSpCas9	negative selection	5411765
12967293	12967316	3	+	27661255	K562	viability	GGTCACCCGCACTCCCGCACAGG	IQSEC1	ENSG00000144711	0.12825657352497377	[1386,1332]	[1198,1178]	4	dCas9-KRAB	negative selection	5487139
12967431	12967454	3	+	27661255	K562	viability	GTTGCAGTGCAGGCACCACATGG	IQSEC1	ENSG00000144711	0.19790003261628292	[898,1130]	[1038,829]	6	dCas9-KRAB	negative selection	5487140
12967699	12967722	3	+	27661255	K562	viability	GAGGCCGGGCCGGAGGAATGTGG	IQSEC1	ENSG00000144711	-0.0356879703996239	[1285,1429]	[1194,937]	-1	dCas9-KRAB	negative selection	5487141
12967223	12967246	3	-	27661255	K562	viability	GGGTGCGTCCGCCAGACTGTGGG	IQSEC1	ENSG00000144711	0.09335778975769604	[2291,2546]	[2267,1878]	3	dCas9-KRAB	negative selection	5487142
12967288	12967311	3	-	27661255	K562	viability	GCGGGAGTGCGGGTGACCGTCGG	IQSEC1	ENSG00000144711	-0.044030843362521166	[243,183]	[157,173]	-2	dCas9-KRAB	negative selection	5487143
12967545	12967568	3	-	27661255	K562	viability	GTCTCCGGGTGGCCGGGTGTCGG	IQSEC1	ENSG00000144711	0.11688372088377486	[643,855]	[661,632]	4	dCas9-KRAB	negative selection	5487144
12924680	12924703	3	-	27260156	BXPC3	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.23141087056261989	[750]	[1036,913,885,817]	5	hSpCas9	negative selection	5549680
12924573	12924596	3	+	27260156	BXPC3	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.18430193267826112	[1253]	[1085,1058,1213,1277]	-4	hSpCas9	negative selection	5549681
12941746	12941769	3	+	27260156	BXPC3	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.008966672156251576	[950]	[976,892,984,1112]	0	hSpCas9	negative selection	5549682
12936646	12936669	3	-	27260156	BXPC3	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.1492056200747478	[130]	[162,67,132,128]	-3	hSpCas9	negative selection	5613936
12936067	12936090	3	-	27260156	BXPC3	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.45938401855640243	[380]	[236,239,306,394]	-7	hSpCas9	negative selection	5613937
12941718	12941741	3	-	27260156	BXPC3	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.17067561711926418	[570]	[436,571,476,653]	-4	hSpCas9	negative selection	5613938
12924680	12924703	3	-	27260156	A673	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.16534001728786551	[750]	[1140,971,798,1156]	4	hSpCas9	negative selection	5670931
12924573	12924596	3	+	27260156	A673	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.1481524853092231	[1253]	[1505,1292,1346,1301]	-4	hSpCas9	negative selection	5670932
12941746	12941769	3	+	27260156	A673	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.13164395880995383	[950]	[1468,1252,1001,1307]	3	hSpCas9	negative selection	5670933
12936646	12936669	3	-	27260156	A673	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.030227825426505373	[130]	[162,165,172,138]	0	hSpCas9	negative selection	5735187
12936067	12936090	3	-	27260156	A673	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	0.015203146581126925	[380]	[540,382,420,517]	0	hSpCas9	negative selection	5735188
12941718	12941741	3	-	27260156	A673	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.1429299129072605	[570]	[677,591,614,603]	-4	hSpCas9	negative selection	5735189
12924680	12924703	3	-	27260156	A375	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.146743223674772	[750]	[815,1174,1095,836]	2	hSpCas9	negative selection	5792182
12924573	12924596	3	+	27260156	A375	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	0.023663130387556075	[1253]	[1409,1962,1392,1274]	0	hSpCas9	negative selection	5792183
12941746	12941769	3	+	27260156	A375	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.2777358042694196	[950]	[1185,1856,1478,973]	4	hSpCas9	negative selection	5792184
12936646	12936669	3	-	27260156	A375	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.10074412111879893	[130]	[181,237,78,90]	-1	hSpCas9	negative selection	5856438
12936067	12936090	3	-	27260156	A375	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.30923299208484345	[380]	[330,400,489,233]	-4	hSpCas9	negative selection	5856439
12941718	12941741	3	-	27260156	A375	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.058726647816662786	[570]	[564,882,503,639]	-1	hSpCas9	negative selection	5856440
12924680	12924703	3	-	27260156	COLO741	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.30741632988054923	[750]	[1490,1034,1067]	6	hSpCas9	negative selection	5913433
12924573	12924596	3	+	27260156	COLO741	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.3475786338589688	[1253]	[1324,1150,1300]	-6	hSpCas9	negative selection	5913434
12941746	12941769	3	+	27260156	COLO741	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.09752713136165347	[950]	[1578,1021,1317]	2	hSpCas9	negative selection	5913435
12936646	12936669	3	-	27260156	COLO741	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.11746838578110519	[130]	[229,159,159]	2	hSpCas9	negative selection	5977689
12936067	12936090	3	-	27260156	COLO741	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.3396207971994606	[380]	[468,442,257]	-6	hSpCas9	negative selection	5977690
12941718	12941741	3	-	27260156	COLO741	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.17742768687782515	[570]	[769,705,480]	-4	hSpCas9	negative selection	5977691
12924680	12924703	3	-	27260156	CAL120	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.16601017175157873	[750]	[1322,849,1013]	2	hSpCas9	negative selection	6034684
12924573	12924596	3	+	27260156	CAL120	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-1.0269251975385403	[1253]	[755,850,689]	-8	hSpCas9	negative selection	6034685
12941746	12941769	3	+	27260156	CAL120	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.06738870669811892	[950]	[1751,998,1048]	1	hSpCas9	negative selection	6034686
12936646	12936669	3	-	27260156	CAL120	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.4983133859219391	[130]	[237,88,38]	-6	hSpCas9	negative selection	6098940
12936067	12936090	3	-	27260156	CAL120	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.15290643140377963	[380]	[447,610,226]	-2	hSpCas9	negative selection	6098941
12941718	12941741	3	-	27260156	CAL120	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.4532053558415158	[570]	[665,511,402]	-6	hSpCas9	negative selection	6098942
12924680	12924703	3	-	27260156	CADOES1	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	-0.06829236780414039	[750]	[715,509,650,791]	-1	hSpCas9	negative selection	6155935
12924573	12924596	3	+	27260156	CADOES1	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.3048811402232112	[1253]	[943,1032,847,951]	-5	hSpCas9	negative selection	6155936
12941746	12941769	3	+	27260156	CADOES1	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.16277146132372156	[950]	[637,976,787,756]	-3	hSpCas9	negative selection	6155937
12936646	12936669	3	-	27260156	CADOES1	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.5111986502380985	[130]	[29,168,89,51]	-7	hSpCas9	negative selection	6220191
12936067	12936090	3	-	27260156	CADOES1	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.22916049970484031	[380]	[358,294,254,299]	-4	hSpCas9	negative selection	6220192
12941718	12941741	3	-	27260156	CADOES1	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.3897501147269762	[570]	[275,433,422,491]	-6	hSpCas9	negative selection	6220193
12924680	12924703	3	-	27260156	EWS502	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.20419200245747893	[750]	[834,876,1018,945]	3	hSpCas9	negative selection	6277186
12924573	12924596	3	+	27260156	EWS502	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.10946625085725437	[1253]	[1148,1298,1316,1157]	-2	hSpCas9	negative selection	6277187
12941746	12941769	3	+	27260156	EWS502	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.006563419142966875	[950]	[1035,974,1006,1024]	0	hSpCas9	negative selection	6277188
12936646	12936669	3	-	27260156	EWS502	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.1730813964006641	[130]	[105,56,262,214]	3	hSpCas9	negative selection	6341442
12936067	12936090	3	-	27260156	EWS502	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.3129059822513526	[380]	[258,316,400,330]	-5	hSpCas9	negative selection	6341443
12941718	12941741	3	-	27260156	EWS502	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.2762218067635263	[570]	[480,521,396,602]	-5	hSpCas9	negative selection	6341444
12924680	12924703	3	-	27260156	EW8	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.1653045484913923	[750]	[679,766,528,777]	3	hSpCas9	negative selection	6398437
12924573	12924596	3	+	27260156	EW8	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.1750206107679455	[1253]	[1067,773,905,866]	-3	hSpCas9	negative selection	6398438
12941746	12941769	3	+	27260156	EW8	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.008017428133731963	[950]	[783,828,715,779]	0	hSpCas9	negative selection	6398439
12936646	12936669	3	-	27260156	EW8	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.1802758402380873	[130]	[144,126,60,52]	-3	hSpCas9	negative selection	6462693
12936067	12936090	3	-	27260156	EW8	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.19205865045464598	[380]	[371,200,235,287]	-4	hSpCas9	negative selection	6462694
12941718	12941741	3	-	27260156	EW8	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.1533271264916214	[570]	[424,329,388,523]	-3	hSpCas9	negative selection	6462695
12924680	12924703	3	-	27260156	CORL105	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.25033969209615237	[750]	[1080,936,1215,978]	5	hSpCas9	negative selection	6519688
12924573	12924596	3	+	27260156	CORL105	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.08284595225747138	[1253]	[1545,1162,1463,1392]	-1	hSpCas9	negative selection	6519689
12941746	12941769	3	+	27260156	CORL105	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.21242652982224186	[950]	[1121,1155,1596,1328]	4	hSpCas9	negative selection	6519690
12936646	12936669	3	-	27260156	CORL105	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.35175283990836226	[130]	[249,130,177,223]	6	hSpCas9	negative selection	6583944
12936067	12936090	3	-	27260156	CORL105	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.12956278585016934	[380]	[395,420,400,410]	-2	hSpCas9	negative selection	6583945
12941718	12941741	3	-	27260156	CORL105	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.07230244014063186	[570]	[810,684,598,447]	-1	hSpCas9	negative selection	6583946
12924680	12924703	3	-	27260156	HS294T	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.09046453934835452	[750]	[295,295,317,330]	1	hSpCas9	negative selection	6640939
12924573	12924596	3	+	27260156	HS294T	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	0.028407303939525397	[1253]	[753,371,345,480]	0	hSpCas9	negative selection	6640940
12941746	12941769	3	+	27260156	HS294T	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.03081316283211133	[950]	[351,370,388,394]	0	hSpCas9	negative selection	6640941
12936646	12936669	3	-	27260156	HS294T	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.3558190331724227	[130]	[32,55,35,31]	-5	hSpCas9	negative selection	6705195
12936067	12936090	3	-	27260156	HS294T	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.16561484241692304	[380]	[131,100,145,149]	-2	hSpCas9	negative selection	6705196
12941718	12941741	3	-	27260156	HS294T	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	0.22142170873963124	[570]	[310,245,168,305]	3	hSpCas9	negative selection	6705197
12924680	12924703	3	-	27260156	HCC44	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.3526971920569617	[750]	[1041,810,1076,1421]	6	hSpCas9	negative selection	6762190
12924573	12924596	3	+	27260156	HCC44	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.028084668427238446	[1253]	[1620,1060,1780,1229]	0	hSpCas9	negative selection	6762191
12941746	12941769	3	+	27260156	HCC44	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.21139705963655686	[950]	[1037,1104,1530,1343]	3	hSpCas9	negative selection	6762192
12936646	12936669	3	-	27260156	HCC44	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.17905274078776934	[130]	[228,65,198,199]	3	hSpCas9	negative selection	6826446
12936067	12936090	3	-	27260156	HCC44	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.2547332170847265	[380]	[457,304,303,380]	-4	hSpCas9	negative selection	6826447
12941718	12941741	3	-	27260156	HCC44	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.4166274432457755	[570]	[491,225,585,675]	-6	hSpCas9	negative selection	6826448
12924680	12924703	3	-	27260156	G402	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.1777955315989448	[750]	[1621,779,1009,810]	2	hSpCas9	negative selection	6883441
12924573	12924596	3	+	27260156	G402	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.4294042934503698	[1253]	[1361,1134,1129,954]	-5	hSpCas9	negative selection	6883442
12941746	12941769	3	+	27260156	G402	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.32712435834865516	[950]	[1832,967,1915,1141]	4	hSpCas9	negative selection	6883443
12936646	12936669	3	-	27260156	G402	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.7047312491470805	[130]	[276,371,289,117]	8	hSpCas9	negative selection	6947697
12936067	12936090	3	-	27260156	G402	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.28162804361603744	[380]	[357,322,259,570]	-4	hSpCas9	negative selection	6947698
12941718	12941741	3	-	27260156	G402	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.19385487587965333	[570]	[820,507,374,747]	-2	hSpCas9	negative selection	6947699
12924680	12924703	3	-	27260156	L33	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.28169822375103226	[750]	[824,319,646,1017]	6	hSpCas9	negative selection	7004692
12924573	12924596	3	+	27260156	L33	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.3714863469186498	[1253]	[983,411,606,921]	-7	hSpCas9	negative selection	7004693
12941746	12941769	3	+	27260156	L33	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.11653585512966302	[950]	[821,401,532,858]	-3	hSpCas9	negative selection	7004694
12936646	12936669	3	-	27260156	L33	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.03531513033036027	[130]	[130,40,90,160]	0	hSpCas9	negative selection	7068948
12936067	12936090	3	-	27260156	L33	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.09273975792091832	[380]	[342,120,223,433]	-2	hSpCas9	negative selection	7068949
12941718	12941741	3	-	27260156	L33	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.08340585781736584	[570]	[440,248,334,575]	-2	hSpCas9	negative selection	7068950
12924680	12924703	3	-	27260156	K562	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.5351304354226798	[750]	[1172,1150,750,826]	6	hSpCas9	negative selection	7125943
12924573	12924596	3	+	27260156	K562	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.5437633832106201	[1253]	[909,625,858,670]	-6	hSpCas9	negative selection	7125944
12941746	12941769	3	+	27260156	K562	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.01795478636473047	[950]	[745,809,858,973]	0	hSpCas9	negative selection	7125945
12936646	12936669	3	-	27260156	K562	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.9366820371152389	[130]	[126,51,48,23]	-8	hSpCas9	negative selection	7190199
12936067	12936090	3	-	27260156	K562	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.17924231230724397	[380]	[297,354,224,315]	-2	hSpCas9	negative selection	7190200
12941718	12941741	3	-	27260156	K562	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.5195176312591121	[570]	[301,340,282,467]	-6	hSpCas9	negative selection	7190201
12924680	12924703	3	-	27260156	HT29	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.08417449615646144	[750]	[1008,1094,930,856]	1	hSpCas9	negative selection	7247194
12924573	12924596	3	+	27260156	HT29	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.020385407736805305	[1253]	[1396,1399,1692,1494]	0	hSpCas9	negative selection	7247195
12941746	12941769	3	+	27260156	HT29	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.05128977443078786	[950]	[1241,1389,1235,963]	1	hSpCas9	negative selection	7247196
12936646	12936669	3	-	27260156	HT29	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.12227954892245418	[130]	[161,167,108,147]	-3	hSpCas9	negative selection	7311450
12936067	12936090	3	-	27260156	HT29	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.07988889700544366	[380]	[449,445,549,319]	-2	hSpCas9	negative selection	7311451
12941718	12941741	3	-	27260156	HT29	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.12832879233390126	[570]	[463,707,688,663]	-3	hSpCas9	negative selection	7311452
12924680	12924703	3	-	27260156	MHHES1	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.5521294595799049	[750]	[1494,1376,1013,1117]	8	hSpCas9	negative selection	7368445
12924573	12924596	3	+	27260156	MHHES1	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.07503355737037043	[1253]	[1779,1648,922,1114]	-1	hSpCas9	negative selection	7368446
12941746	12941769	3	+	27260156	MHHES1	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.024308444695580356	[950]	[1233,1259,1112,822]	0	hSpCas9	negative selection	7368447
12936646	12936669	3	-	27260156	MHHES1	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.20338512415527799	[130]	[156,165,313,62]	4	hSpCas9	negative selection	7432701
12936067	12936090	3	-	27260156	MHHES1	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.025131212845572848	[380]	[545,489,357,326]	0	hSpCas9	negative selection	7432702
12941718	12941741	3	-	27260156	MHHES1	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.31676820241175674	[570]	[573,500,596,411]	-5	hSpCas9	negative selection	7432703
12924680	12924703	3	-	27260156	MEWO	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.39644040200772435	[750]	[909,997,862]	8	hSpCas9	negative selection	7489696
12924573	12924596	3	+	27260156	MEWO	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.04632149523761342	[1253]	[1233,1152,1039]	-1	hSpCas9	negative selection	7489697
12941746	12941769	3	+	27260156	MEWO	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.11383225158306742	[950]	[1241,793,906]	2	hSpCas9	negative selection	7489698
12936646	12936669	3	-	27260156	MEWO	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.18231045513883926	[130]	[164,178,77]	4	hSpCas9	negative selection	7553952
12936067	12936090	3	-	27260156	MEWO	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.30877060187211025	[380]	[246,359,247]	-6	hSpCas9	negative selection	7553953
12941718	12941741	3	-	27260156	MEWO	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.19654727253608847	[570]	[561,458,395]	-4	hSpCas9	negative selection	7553954
12924680	12924703	3	-	27260156	LNCAPCLONEFGC	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.17054857854505212	[750]	[788,517,899,890]	2	hSpCas9	negative selection	7610947
12924573	12924596	3	+	27260156	LNCAPCLONEFGC	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.2988664845299953	[1253]	[1015,751,1128,835]	-5	hSpCas9	negative selection	7610948
12941746	12941769	3	+	27260156	LNCAPCLONEFGC	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.09211934210511408	[950]	[933,657,1299,853]	1	hSpCas9	negative selection	7610949
12936646	12936669	3	-	27260156	LNCAPCLONEFGC	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.06716654752156392	[130]	[155,94,103,96]	-1	hSpCas9	negative selection	7675203
12936067	12936090	3	-	27260156	LNCAPCLONEFGC	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.26316992047675036	[380]	[256,275,290,327]	-4	hSpCas9	negative selection	7675204
12941718	12941741	3	-	27260156	LNCAPCLONEFGC	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.3065937304348707	[570]	[426,359,557,351]	-5	hSpCas9	negative selection	7675205
12924680	12924703	3	-	27260156	PANC0327	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.3741916170116737	[750]	[1099,422,1070,940]	5	hSpCas9	negative selection	7732198
12924573	12924596	3	+	27260156	PANC0327	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.45152112788290266	[1253]	[1090,690,892,621]	-6	hSpCas9	negative selection	7732199
12941746	12941769	3	+	27260156	PANC0327	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.08705557063905722	[950]	[964,736,811,1100]	1	hSpCas9	negative selection	7732200
12936646	12936669	3	-	27260156	PANC0327	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.09466143156183016	[130]	[107,58,18,255]	-1	hSpCas9	negative selection	7796454
12936067	12936090	3	-	27260156	PANC0327	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.20815538968749736	[380]	[280,299,329,258]	-3	hSpCas9	negative selection	7796455
12941718	12941741	3	-	27260156	PANC0327	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.25586322605041184	[570]	[475,464,376,379]	-4	hSpCas9	negative selection	7796456
12924680	12924703	3	-	27260156	NCIH2009	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.2659700465674055	[750]	[1352,1148,1300]	3	hSpCas9	negative selection	7853449
12924573	12924596	3	+	27260156	NCIH2009	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.1133281493366547	[1253]	[1809,1227,1862]	-1	hSpCas9	negative selection	7853450
12941746	12941769	3	+	27260156	NCIH2009	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.10865563227706643	[950]	[1463,1320,953]	-1	hSpCas9	negative selection	7853451
12936646	12936669	3	-	27260156	NCIH2009	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.09795400594194148	[130]	[94,265,134]	-1	hSpCas9	negative selection	7917705
12936067	12936090	3	-	27260156	NCIH2009	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.5652626713338026	[380]	[557,240,320]	-6	hSpCas9	negative selection	7917706
12941718	12941741	3	-	27260156	NCIH2009	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	0.021781234066424293	[570]	[1248,652,615]	0	hSpCas9	negative selection	7917707
12924680	12924703	3	-	27260156	NCIH1373	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.0008825833325508681	[750]	[846,828,852,219]	0	hSpCas9	negative selection	7974700
12924573	12924596	3	+	27260156	NCIH1373	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-1.123179112511029	[1253]	[834,381,436,264]	-8	hSpCas9	negative selection	7974701
12941746	12941769	3	+	27260156	NCIH1373	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.24276720981014344	[950]	[970,1089,939,542]	2	hSpCas9	negative selection	7974702
12936646	12936669	3	-	27260156	NCIH1373	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.15649882654267588	[130]	[161,101,164,26]	-1	hSpCas9	negative selection	8038956
12936067	12936090	3	-	27260156	NCIH1373	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.18750268357364536	[380]	[289,451,518,52]	-2	hSpCas9	negative selection	8038957
12941718	12941741	3	-	27260156	NCIH1373	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.49230552984007225	[570]	[542,312,612,96]	-5	hSpCas9	negative selection	8038958
12924680	12924703	3	-	27260156	PATU8902	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	-0.03180402793560333	[750]	[1073,1154,586,1429]	0	hSpCas9	negative selection	8095951
12924573	12924596	3	+	27260156	PATU8902	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.26243497383453684	[1253]	[1214,1579,1273,1839]	-3	hSpCas9	negative selection	8095952
12941746	12941769	3	+	27260156	PATU8902	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.0017946131955886013	[950]	[1470,990,1219,1662]	0	hSpCas9	negative selection	8095953
12936646	12936669	3	-	27260156	PATU8902	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.8658580708360886	[130]	[85,59,157,77]	-7	hSpCas9	negative selection	8160207
12936067	12936090	3	-	27260156	PATU8902	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-1.0009688950374644	[380]	[318,252,284,185]	-7	hSpCas9	negative selection	8160208
12941718	12941741	3	-	27260156	PATU8902	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.15589372637768428	[570]	[840,814,562,661]	-1	hSpCas9	negative selection	8160209
12924680	12924703	3	-	27260156	PANC1	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.09489166289828721	[750]	[630,1057,645,514]	1	hSpCas9	negative selection	8217202
12924573	12924596	3	+	27260156	PANC1	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.04639789662655147	[1253]	[1012,1025,1117,1001]	0	hSpCas9	negative selection	8217203
12941746	12941769	3	+	27260156	PANC1	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.24210897030968348	[950]	[1015,1039,990,836]	4	hSpCas9	negative selection	8217204
12936646	12936669	3	-	27260156	PANC1	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.130224365571193	[130]	[162,105,80,64]	-2	hSpCas9	negative selection	8281458
12936067	12936090	3	-	27260156	PANC1	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.05198072268132947	[380]	[264,383,271,345]	-1	hSpCas9	negative selection	8281459
12941718	12941741	3	-	27260156	PANC1	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.1934896360592197	[570]	[448,501,347,423]	-3	hSpCas9	negative selection	8281460
12924680	12924703	3	-	27260156	PANC0813	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.10818234351193223	[750]	[1029,829,973,973]	1	hSpCas9	negative selection	8338453
12924573	12924596	3	+	27260156	PANC0813	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	0.11157614453385412	[1253]	[2255,1420,1384,1373]	1	hSpCas9	negative selection	8338454
12941746	12941769	3	+	27260156	PANC0813	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.058529840435969094	[950]	[1223,1294,1247,904]	1	hSpCas9	negative selection	8338455
12936646	12936669	3	-	27260156	PANC0813	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.18629977432096756	[130]	[161,91,182,107]	-3	hSpCas9	negative selection	8402709
12936067	12936090	3	-	27260156	PANC0813	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	0.012695659018247984	[380]	[663,480,419,269]	0	hSpCas9	negative selection	8402710
12941718	12941741	3	-	27260156	PANC0813	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.29655844515281243	[570]	[542,732,442,467]	-5	hSpCas9	negative selection	8402711
12924680	12924703	3	-	27260156	RDES	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.22537679378051623	[750]	[714,953,1092,1376]	3	hSpCas9	negative selection	8459704
12924573	12924596	3	+	27260156	RDES	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.025968807676741923	[1253]	[1126,1316,1680,1609]	0	hSpCas9	negative selection	8459705
12941746	12941769	3	+	27260156	RDES	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.1266082841861349	[950]	[1099,1106,1101,1499]	2	hSpCas9	negative selection	8459706
12936646	12936669	3	-	27260156	RDES	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.09908214732649867	[130]	[120,149,162,125]	-2	hSpCas9	negative selection	8523960
12936067	12936090	3	-	27260156	RDES	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.13117013655103182	[380]	[365,307,505,432]	-2	hSpCas9	negative selection	8523961
12941718	12941741	3	-	27260156	RDES	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.13788672943233335	[570]	[443,581,704,691]	-2	hSpCas9	negative selection	8523962
12924680	12924703	3	-	27260156	PC3	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.07851240275295424	[750]	[446,863,1472,715]	1	hSpCas9	negative selection	8580955
12924573	12924596	3	+	27260156	PC3	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.1872002750339239	[1253]	[609,1109,1818,1256]	-4	hSpCas9	negative selection	8580956
12941746	12941769	3	+	27260156	PC3	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.04353446873833278	[950]	[625,854,1505,1200]	1	hSpCas9	negative selection	8580957
12936646	12936669	3	-	27260156	PC3	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.2301511097848239	[130]	[59,44,378,81]	-5	hSpCas9	negative selection	8645211
12936067	12936090	3	-	27260156	PC3	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.14632230827194637	[380]	[229,297,540,399]	-3	hSpCas9	negative selection	8645212
12941718	12941741	3	-	27260156	PC3	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.09947044684565834	[570]	[250,528,1197,487]	-2	hSpCas9	negative selection	8645213
12924680	12924703	3	-	27260156	PATU8988T	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.19832086954036243	[750]	[582,1004,955,797]	3	hSpCas9	negative selection	8702206
12924573	12924596	3	+	27260156	PATU8988T	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.561519115259999	[1253]	[750,994,788,760]	-7	hSpCas9	negative selection	8702207
12941746	12941769	3	+	27260156	PATU8988T	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.08751846406104269	[950]	[904,843,993,1164]	1	hSpCas9	negative selection	8702208
12936646	12936669	3	-	27260156	PATU8988T	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.3814695231054752	[130]	[83,53,59,194]	-6	hSpCas9	negative selection	8766462
12936067	12936090	3	-	27260156	PATU8988T	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.25967727365337767	[380]	[335,199,394,285]	-4	hSpCas9	negative selection	8766463
12941718	12941741	3	-	27260156	PATU8988T	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.2640571222627126	[570]	[271,666,460,456]	-4	hSpCas9	negative selection	8766464
12924680	12924703	3	-	27260156	T47D	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.15871127350298697	[750]	[892,913,1084,1018]	3	hSpCas9	negative selection	8823457
12924573	12924596	3	+	27260156	T47D	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.2367487458798856	[1253]	[1330,1206,1242,1178]	-5	hSpCas9	negative selection	8823458
12941746	12941769	3	+	27260156	T47D	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.15420235351880318	[950]	[1088,917,972,1009]	-3	hSpCas9	negative selection	8823459
12936646	12936669	3	-	27260156	T47D	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.019052960108197903	[130]	[162,112,182,162]	0	hSpCas9	negative selection	8887713
12936067	12936090	3	-	27260156	T47D	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.1481785205364734	[380]	[337,425,433,400]	-3	hSpCas9	negative selection	8887714
12941718	12941741	3	-	27260156	T47D	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.24583045407308535	[570]	[520,546,532,646]	-5	hSpCas9	negative selection	8887715
12924680	12924703	3	-	27260156	SU8686	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.24366334886125796	[750]	[833,874,721,1130]	4	hSpCas9	negative selection	8944708
12924573	12924596	3	+	27260156	SU8686	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.1697590063186103	[1253]	[1014,931,1263,1264]	-3	hSpCas9	negative selection	8944709
12941746	12941769	3	+	27260156	SU8686	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.016027311987319992	[950]	[903,876,864,1114]	0	hSpCas9	negative selection	8944710
12936646	12936669	3	-	27260156	SU8686	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.201511121248237	[130]	[94,132,110,110]	-4	hSpCas9	negative selection	9008964
12936067	12936090	3	-	27260156	SU8686	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.1935305922082986	[380]	[333,276,309,417]	-3	hSpCas9	negative selection	9008965
12941718	12941741	3	-	27260156	SU8686	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.38275270322274324	[570]	[283,409,396,705]	-6	hSpCas9	negative selection	9008966
12924680	12924703	3	-	27260156	SKES1	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.30722590375476766	[750]	[1150,955,706,921]	6	hSpCas9	negative selection	9065959
12924573	12924596	3	+	27260156	SKES1	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.15592445504547614	[1253]	[970,1463,1073,1004]	-3	hSpCas9	negative selection	9065960
12941746	12941769	3	+	27260156	SKES1	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.044010618775819355	[950]	[1033,1065,917,910]	1	hSpCas9	negative selection	9065961
12936646	12936669	3	-	27260156	SKES1	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.07943770620288926	[130]	[119,97,194,80]	-2	hSpCas9	negative selection	9130215
12936067	12936090	3	-	27260156	SKES1	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	0.032167417350104976	[380]	[497,342,436,292]	0	hSpCas9	negative selection	9130216
12941718	12941741	3	-	27260156	SKES1	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	0.007770899212057425	[570]	[763,387,709,440]	0	hSpCas9	negative selection	9130217
12924680	12924703	3	-	27260156	TOV112D	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.3228738515008065	[750]	[993,1244,948,660]	6	hSpCas9	negative selection	9187210
12924573	12924596	3	+	27260156	TOV112D	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.11133138558951883	[1253]	[1427,1335,904,1047]	-2	hSpCas9	negative selection	9187211
12941746	12941769	3	+	27260156	TOV112D	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	0.14808412326189346	[950]	[1011,1286,979,995]	3	hSpCas9	negative selection	9187212
12936646	12936669	3	-	27260156	TOV112D	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	-0.04264614179099846	[130]	[110,73,225,84]	-1	hSpCas9	negative selection	9251466
12936067	12936090	3	-	27260156	TOV112D	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.3745789800506457	[380]	[444,361,206,194]	-6	hSpCas9	negative selection	9251467
12941718	12941741	3	-	27260156	TOV112D	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.2627451196341763	[570]	[554,545,404,424]	-5	hSpCas9	negative selection	9251468
12924680	12924703	3	-	27260156	TC71	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.15180070411857027	[750]	[818,837,861,1071]	4	hSpCas9	negative selection	9308461
12924573	12924596	3	+	27260156	TC71	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.1854598665325553	[1253]	[1306,1176,995,1255]	-5	hSpCas9	negative selection	9308462
12941746	12941769	3	+	27260156	TC71	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.14341852743119432	[950]	[991,1041,949,690]	-4	hSpCas9	negative selection	9308463
12936646	12936669	3	-	27260156	TC71	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.13097298733324836	[130]	[139,140,164,169]	3	hSpCas9	negative selection	9372717
12936067	12936090	3	-	27260156	TC71	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.025890548140357184	[380]	[456,455,340,347]	0	hSpCas9	negative selection	9372718
12941718	12941741	3	-	27260156	TC71	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.25401751248611276	[570]	[543,526,476,504]	-6	hSpCas9	negative selection	9372719
12924680	12924703	3	-	27260156	TC32	viability	TTTGTGCCCGACACGCCCGTCGG	IQSEC1	ENSG00000144711	0.017721342078131253	[750]	[691,466,846,942]	0	hSpCas9	negative selection	9429712
12924573	12924596	3	+	27260156	TC32	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.3512623322804964	[1253]	[732,810,1185,1026]	-6	hSpCas9	negative selection	9429713
12941746	12941769	3	+	27260156	TC32	viability	GACGTGTGCTCGTAGTGATCCGG	IQSEC1	ENSG00000144711	-0.010639568302585278	[950]	[915,600,1007,1108]	0	hSpCas9	negative selection	9429714
12936646	12936669	3	-	27260156	TC32	viability	GCGCCTGGTAACCCGCCATGCGG	IQSEC1	ENSG00000144711	0.3763968164256086	[130]	[131,132,241,149]	6	hSpCas9	negative selection	9493968
12936067	12936090	3	-	27260156	TC32	viability	CCGGCCGTCCAGCACCGAGTCGG	IQSEC1	ENSG00000144711	-0.06063195557055068	[380]	[340,302,503,240]	-1	hSpCas9	negative selection	9493969
12941718	12941741	3	-	27260156	TC32	viability	GAGCCTATGGGCTGTACTCGGGG	IQSEC1	ENSG00000144711	-0.2938542066627925	[570]	[355,342,669,442]	-5	hSpCas9	negative selection	9493970
12915614	12915637	3	+	27869803	HPAFII	viability after 27 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	0.41743801540487285	[151]	[55,148,NaN]	3	hSpCas9	negative selection	9582556
12922157	12922180	3	-	27869803	HPAFII	viability after 27 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	0.927580454375704	[0]	[0,0,NaN]	7	hSpCas9	negative selection	9582557
12924610	12924633	3	-	27869803	HPAFII	viability after 27 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	0.5593086150060516	[618]	[496,464,NaN]	4	hSpCas9	negative selection	9582558
12936169	12936192	3	+	27869803	HPAFII	viability after 27 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.08670074614800849	[374]	[228,192,NaN]	0	hSpCas9	negative selection	9582565
12941648	12941671	3	-	27869803	HPAFII	viability after 27 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	1.0225622730999557	[174]	[361,40,NaN]	8	hSpCas9	negative selection	9582566
12967386	12967409	3	-	27869803	HPAFII	viability after 27 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	0.05371233419409793	[399]	[412,55,NaN]	0	hSpCas9	negative selection	9582567
12915614	12915637	3	+	27869803	HPAFII	viability after 15 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	0.8351704348078004	[151]	[222,333,NaN]	8	hSpCas9	negative selection	9665005
12922157	12922180	3	-	27869803	HPAFII	viability after 15 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	-0.10397428375416773	[0]	[0,0,NaN]	-1	hSpCas9	negative selection	9665006
12924610	12924633	3	-	27869803	HPAFII	viability after 15 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	0.30365479677211393	[618]	[883,781,NaN]	3	hSpCas9	negative selection	9665007
12936169	12936192	3	+	27869803	HPAFII	viability after 15 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.05455204269857372	[374]	[585,264,NaN]	0	hSpCas9	negative selection	9665014
12941648	12941671	3	-	27869803	HPAFII	viability after 15 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.45483604752825807	[174]	[443,141,NaN]	5	hSpCas9	negative selection	9665015
12967386	12967409	3	-	27869803	HPAFII	viability after 15 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	-0.5301595856803951	[399]	[375,248,NaN]	-5	hSpCas9	negative selection	9665016
12915614	12915637	3	+	27869803	ASPC1	viability after 36 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	0.4713227970509639	[557]	[174,478,167]	5	hSpCas9	negative selection	9747454
12922157	12922180	3	-	27869803	ASPC1	viability after 36 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	-0.5121322953764142	[478]	[245,39,86]	-5	hSpCas9	negative selection	9747455
12924610	12924633	3	-	27869803	ASPC1	viability after 36 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	0.5438979257120131	[1295]	[907,761,396]	5	hSpCas9	negative selection	9747456
12936169	12936192	3	+	27869803	ASPC1	viability after 36 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.3072735234592976	[995]	[425,658,246]	3	hSpCas9	negative selection	9747463
12941648	12941671	3	-	27869803	ASPC1	viability after 36 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.8886443466365654	[476]	[310,87,477]	8	hSpCas9	negative selection	9747464
12967386	12967409	3	-	27869803	ASPC1	viability after 36 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	-0.622859920284564	[963]	[173,140,308]	-6	hSpCas9	negative selection	9747465
12915614	12915637	3	+	27869803	PATU8988S	viability after 35 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	0.4462440078552546	[391]	[261,167,NaN]	5	hSpCas9	negative selection	9829903
12922157	12922180	3	-	27869803	PATU8988S	viability after 35 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	0.49077666832545264	[408]	[218,243,NaN]	5	hSpCas9	negative selection	9829904
12924610	12924633	3	-	27869803	PATU8988S	viability after 35 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	0.10093671735045806	[1219]	[510,542,NaN]	1	hSpCas9	negative selection	9829905
12936169	12936192	3	+	27869803	PATU8988S	viability after 35 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.30676634556405435	[832]	[405,423,NaN]	3	hSpCas9	negative selection	9829912
12941648	12941671	3	-	27869803	PATU8988S	viability after 35 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.4942937430095803	[372]	[260,161,NaN]	5	hSpCas9	negative selection	9829913
12967386	12967409	3	-	27869803	PATU8988S	viability after 35 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	0.47476218649377105	[607]	[250,429,NaN]	5	hSpCas9	negative selection	9829914
12915614	12915637	3	+	27869803	PATU8988S	viability after 31 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	0.12562509640508224	[391]	[210,118,NaN]	1	hSpCas9	negative selection	9912352
12922157	12922180	3	-	27869803	PATU8988S	viability after 31 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	0.2615935222004528	[408]	[136,269,NaN]	3	hSpCas9	negative selection	9912353
12924610	12924633	3	-	27869803	PATU8988S	viability after 31 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	0.15836913828948185	[1219]	[490,608,NaN]	2	hSpCas9	negative selection	9912354
12936169	12936192	3	+	27869803	PATU8988S	viability after 31 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.21537791136640527	[832]	[349,430,NaN]	2	hSpCas9	negative selection	9912361
12941648	12941671	3	-	27869803	PATU8988S	viability after 31 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.7678118467342601	[372]	[265,236,NaN]	8	hSpCas9	negative selection	9912362
12967386	12967409	3	-	27869803	PATU8988S	viability after 31 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	-0.06552541292856627	[607]	[188,285,NaN]	0	hSpCas9	negative selection	9912363
12915614	12915637	3	+	27869803	HPAFII	viability after 35 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	0.7903007168519182	[151]	[54,220,NaN]	5	hSpCas9	negative selection	9994801
12922157	12922180	3	-	27869803	HPAFII	viability after 35 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	0.9820885529966752	[0]	[0,0,NaN]	6	hSpCas9	negative selection	9994802
12924610	12924633	3	-	27869803	HPAFII	viability after 35 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	0.12677892423979786	[618]	[288,401,NaN]	0	hSpCas9	negative selection	9994803
12936169	12936192	3	+	27869803	HPAFII	viability after 35 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.23109802640192784	[374]	[117,210,NaN]	-1	hSpCas9	negative selection	9994810
12941648	12941671	3	-	27869803	HPAFII	viability after 35 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	1.128584079818911	[174]	[307,64,NaN]	7	hSpCas9	negative selection	9994811
12967386	12967409	3	-	27869803	HPAFII	viability after 35 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	0.361959327443226	[399]	[398,103,NaN]	2	hSpCas9	negative selection	9994812
12915614	12915637	3	+	27869803	HPAFII	viability after 31 days	GCTTCTCCACCTTCTGCACCTGG	IQSEC1	ENSG00000144711	0.5913889768766021	[151]	[50,212,NaN]	4	hSpCas9	negative selection	10077250
12922157	12922180	3	-	27869803	HPAFII	viability after 31 days	GGCGCACATCCGTGTCCAAGGGG	IQSEC1	ENSG00000144711	0.8333711996752582	[0]	[0,0,NaN]	6	hSpCas9	negative selection	10077251
12924610	12924633	3	-	27869803	HPAFII	viability after 31 days	TCGGCGAGTTCCTGGGCAACCGG	IQSEC1	ENSG00000144711	0.3193449210635322	[618]	[320,555,NaN]	2	hSpCas9	negative selection	10077252
12936169	12936192	3	+	27869803	HPAFII	viability after 31 days	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.02909074876710338	[374]	[141,293,NaN]	0	hSpCas9	negative selection	10077259
12941648	12941671	3	-	27869803	HPAFII	viability after 31 days	GACCTCCATCCTGCGCAAGCAGG	IQSEC1	ENSG00000144711	0.8827459207152055	[174]	[238,117,NaN]	6	hSpCas9	negative selection	10077260
12967386	12967409	3	-	27869803	HPAFII	viability after 31 days	TGGAGCTAGAGCTTGACAGCGGG	IQSEC1	ENSG00000144711	-0.4462252423105436	[399]	[259,60,NaN]	-3	hSpCas9	negative selection	10077261
12936353	12936376	3	+	28162770	P31FUJ	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.15162730893406873	[130]	[170]	1	hSpCas9	negative selection	10175562
12920503	12920526	3	+	28162770	P31FUJ	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	0.159817828756868	[226]	[297]	1	hSpCas9	negative selection	10175563
12941688	12941711	3	-	28162770	P31FUJ	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	-1.508436647027806	[91]	[37]	-7	hSpCas9	negative selection	10175564
12936622	12936645	3	+	28162770	P31FUJ	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.8765227860239622	[234]	[506]	8	hSpCas9	negative selection	10175565
12936169	12936192	3	+	28162770	P31FUJ	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.08476948542884769	[198]	[247]	0	hSpCas9	negative selection	10175566
12935904	12935927	3	+	28162770	P31FUJ	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	-0.24214006899371493	[154]	[153]	-2	hSpCas9	negative selection	10175567
12924573	12924596	3	+	28162770	P31FUJ	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	3.196364371604865e-05	[176]	[207]	0	hSpCas9	negative selection	10175568
12922154	12922177	3	-	28162770	P31FUJ	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	-0.8848789009940718	[65]	[41]	-6	hSpCas9	negative selection	10175569
12922137	12922160	3	-	28162770	P31FUJ	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	-0.5707986679293946	[157]	[124]	-5	hSpCas9	negative selection	10175570
12920553	12920576	3	+	28162770	P31FUJ	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	0.11250620444895798	[354]	[450]	1	hSpCas9	negative selection	10175571
12936353	12936376	3	+	28162770	TF1	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10344928
12920503	12920526	3	+	28162770	TF1	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	NaN	[NaN]	[186]	1	hSpCas9	negative selection	10344929
12941688	12941711	3	-	28162770	TF1	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10344930
12936622	12936645	3	+	28162770	TF1	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10344931
12936169	12936192	3	+	28162770	TF1	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	NaN	[NaN]	[217]	1	hSpCas9	negative selection	10344932
12935904	12935927	3	+	28162770	TF1	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	NaN	[NaN]	[66]	1	hSpCas9	negative selection	10344933
12924573	12924596	3	+	28162770	TF1	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	NaN	[NaN]	[164]	1	hSpCas9	negative selection	10344934
12922154	12922177	3	-	28162770	TF1	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10344935
12922137	12922160	3	-	28162770	TF1	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	NaN	[NaN]	[175]	1	hSpCas9	negative selection	10344936
12920553	12920576	3	+	28162770	TF1	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	NaN	[NaN]	[113]	1	hSpCas9	negative selection	10344937
12936353	12936376	3	+	28162770	SKM1	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	-0.28766527037081735	[28]	[41]	-2	hSpCas9	negative selection	10514294
12920503	12920526	3	+	28162770	SKM1	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	-0.9663916073571804	[41]	[37]	-6	hSpCas9	negative selection	10514295
12941688	12941711	3	-	28162770	SKM1	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	0.32686168789247727	[22]	[50]	3	hSpCas9	negative selection	10514296
12936622	12936645	3	+	28162770	SKM1	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.7005642655612834	[62]	[180]	6	hSpCas9	negative selection	10514297
12936169	12936192	3	+	28162770	SKM1	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.4131961524546764	[57]	[76]	-3	hSpCas9	negative selection	10514298
12935904	12935927	3	+	28162770	SKM1	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	-0.2947546951571365	[33]	[48]	-2	hSpCas9	negative selection	10514299
12924573	12924596	3	+	28162770	SKM1	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-1.2452131287465495	[58]	[43]	-7	hSpCas9	negative selection	10514300
12922154	12922177	3	-	28162770	SKM1	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	0.7994866787242647	[12]	[39]	7	hSpCas9	negative selection	10514301
12922137	12922160	3	-	28162770	SKM1	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	-0.4780472968046443	[25]	[32]	-4	hSpCas9	negative selection	10514302
12920553	12920576	3	+	28162770	SKM1	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	0.6898973405094273	[53]	[153]	6	hSpCas9	negative selection	10514303
12936353	12936376	3	+	28162770	SKM1	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	-0.28766527037081735	[28]	[41]	-2	hSpCas9	negative selection	10683660
12920503	12920526	3	+	28162770	SKM1	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	-0.9663916073571804	[41]	[37]	-6	hSpCas9	negative selection	10683661
12941688	12941711	3	-	28162770	SKM1	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	0.32686168789247727	[22]	[50]	3	hSpCas9	negative selection	10683662
12936622	12936645	3	+	28162770	SKM1	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.7005642655612834	[62]	[180]	6	hSpCas9	negative selection	10683663
12936169	12936192	3	+	28162770	SKM1	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.4131961524546764	[57]	[76]	-3	hSpCas9	negative selection	10683664
12935904	12935927	3	+	28162770	SKM1	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	-0.2947546951571365	[33]	[48]	-2	hSpCas9	negative selection	10683665
12924573	12924596	3	+	28162770	SKM1	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-1.2452131287465495	[58]	[43]	-7	hSpCas9	negative selection	10683666
12922154	12922177	3	-	28162770	SKM1	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	0.7994866787242647	[12]	[39]	7	hSpCas9	negative selection	10683667
12922137	12922160	3	-	28162770	SKM1	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	-0.4780472968046443	[25]	[32]	-4	hSpCas9	negative selection	10683668
12920553	12920576	3	+	28162770	SKM1	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	0.6898973405094273	[53]	[153]	6	hSpCas9	negative selection	10683669
12936353	12936376	3	+	28162770	PL21	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	-0.7900793647180946	[146]	[36]	-5	hSpCas9	negative selection	10853026
12920503	12920526	3	+	28162770	PL21	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	-0.8873232267610192	[186]	[43]	-6	hSpCas9	negative selection	10853027
12941688	12941711	3	-	28162770	PL21	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	-2.953665721589715	[88]	[4]	-9	hSpCas9	negative selection	10853028
12936622	12936645	3	+	28162770	PL21	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.09161515771115096	[206]	[95]	0	hSpCas9	negative selection	10853029
12936169	12936192	3	+	28162770	PL21	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.7577815092109643	[230]	[169]	6	hSpCas9	negative selection	10853030
12935904	12935927	3	+	28162770	PL21	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	-1.531664274561107	[92]	[13]	-7	hSpCas9	negative selection	10853031
12924573	12924596	3	+	28162770	PL21	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	0.6799854093962623	[184]	[128]	6	hSpCas9	negative selection	10853032
12922154	12922177	3	-	28162770	PL21	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	-0.4403179988235393	[52]	[16]	-3	hSpCas9	negative selection	10853033
12922137	12922160	3	-	28162770	PL21	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	-0.10728891070292734	[98]	[39]	-1	hSpCas9	negative selection	10853034
12920553	12920576	3	+	28162770	PL21	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	0.24320833638120587	[197]	[101]	2	hSpCas9	negative selection	10853035
12936353	12936376	3	+	28162770	P31FUJ	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.15162730893406873	[130]	[170]	1	hSpCas9	negative selection	11022392
12920503	12920526	3	+	28162770	P31FUJ	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	0.159817828756868	[226]	[297]	1	hSpCas9	negative selection	11022393
12941688	12941711	3	-	28162770	P31FUJ	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	-1.508436647027806	[91]	[37]	-7	hSpCas9	negative selection	11022394
12936622	12936645	3	+	28162770	P31FUJ	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.8765227860239622	[234]	[506]	8	hSpCas9	negative selection	11022395
12936169	12936192	3	+	28162770	P31FUJ	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.08476948542884769	[198]	[247]	0	hSpCas9	negative selection	11022396
12935904	12935927	3	+	28162770	P31FUJ	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	-0.24214006899371493	[154]	[153]	-2	hSpCas9	negative selection	11022397
12924573	12924596	3	+	28162770	P31FUJ	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	3.196364371604865e-05	[176]	[207]	0	hSpCas9	negative selection	11022398
12922154	12922177	3	-	28162770	P31FUJ	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	-0.8848789009940718	[65]	[41]	-6	hSpCas9	negative selection	11022399
12922137	12922160	3	-	28162770	P31FUJ	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	-0.5707986679293946	[157]	[124]	-5	hSpCas9	negative selection	11022400
12920553	12920576	3	+	28162770	P31FUJ	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	0.11250620444895798	[354]	[450]	1	hSpCas9	negative selection	11022401
12936353	12936376	3	+	28162770	OCIAML5	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.6285592700424238	[42]	[119]	5	hSpCas9	negative selection	11191758
12920503	12920526	3	+	28162770	OCIAML5	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	-0.5145656720561734	[128]	[162]	-4	hSpCas9	negative selection	11191759
12941688	12941711	3	-	28162770	OCIAML5	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	-0.4709764035084907	[42]	[55]	-3	hSpCas9	negative selection	11191760
12936622	12936645	3	+	28162770	OCIAML5	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.418514644023145	[142]	[344]	3	hSpCas9	negative selection	11191761
12936169	12936192	3	+	28162770	OCIAML5	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.21610493177758228	[123]	[259]	1	hSpCas9	negative selection	11191762
12935904	12935927	3	+	28162770	OCIAML5	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	-0.6594214929216011	[48]	[55]	-4	hSpCas9	negative selection	11191763
12924573	12924596	3	+	28162770	OCIAML5	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.11510097669779065	[149]	[249]	-1	hSpCas9	negative selection	11191764
12922154	12922177	3	-	28162770	OCIAML5	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	-1.4843347863635104	[61]	[39]	-7	hSpCas9	negative selection	11191765
12922137	12922160	3	-	28162770	OCIAML5	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	0.026627132913869533	[92]	[170]	0	hSpCas9	negative selection	11191766
12920553	12920576	3	+	28162770	OCIAML5	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	-0.8921440102393323	[145]	[141]	-5	hSpCas9	negative selection	11191767
12936353	12936376	3	+	28162770	EOL1	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.6794352737340031	[191]	[161]	6	hSpCas9	negative selection	11361124
12920503	12920526	3	+	28162770	EOL1	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	-0.20364049759895547	[246]	[112]	-1	hSpCas9	negative selection	11361125
12941688	12941711	3	-	28162770	EOL1	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	0.40098581551352175	[114]	[79]	3	hSpCas9	negative selection	11361126
12936622	12936645	3	+	28162770	EOL1	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	-0.16203991342555618	[411]	[193]	-1	hSpCas9	negative selection	11361127
12936169	12936192	3	+	28162770	EOL1	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.7687901020548161	[341]	[306]	6	hSpCas9	negative selection	11361128
12935904	12935927	3	+	28162770	EOL1	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	0.35626401199600877	[214]	[144]	3	hSpCas9	negative selection	11361129
12924573	12924596	3	+	28162770	EOL1	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.803778904321799	[221]	[66]	-5	hSpCas9	negative selection	11361130
12922154	12922177	3	-	28162770	EOL1	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	1.225056882822991	[94]	[116]	8	hSpCas9	negative selection	11361131
12922137	12922160	3	-	28162770	EOL1	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	-0.07545222842946542	[121]	[60]	0	hSpCas9	negative selection	11361132
12920553	12920576	3	+	28162770	EOL1	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	-0.11082655853135064	[288]	[140]	-1	hSpCas9	negative selection	11361133
12936353	12936376	3	+	28162770	MOLM13	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	0.0212062556492697	[168]	[123]	0	hSpCas9	negative selection	11530490
12920503	12920526	3	+	28162770	MOLM13	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	1.1072996662881114	[311]	[485]	8	hSpCas9	negative selection	11530491
12941688	12941711	3	-	28162770	MOLM13	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	1.670278778233403	[82]	[190]	9	hSpCas9	negative selection	11530492
12936622	12936645	3	+	28162770	MOLM13	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.6283540537378248	[373]	[417]	5	hSpCas9	negative selection	11530493
12936169	12936192	3	+	28162770	MOLM13	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.9166976174786665	[284]	[388]	7	hSpCas9	negative selection	11530494
12935904	12935927	3	+	28162770	MOLM13	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	0.14369111303238935	[158]	[126]	1	hSpCas9	negative selection	11530495
12924573	12924596	3	+	28162770	MOLM13	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.9239903967470124	[411]	[156]	-5	hSpCas9	negative selection	11530496
12922154	12922177	3	-	28162770	MOLM13	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	-1.0997951277447415	[82]	[27]	-5	hSpCas9	negative selection	11530497
12922137	12922160	3	-	28162770	MOLM13	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	-1.8540387133427836	[179]	[35]	-7	hSpCas9	negative selection	11530498
12920553	12920576	3	+	28162770	MOLM13	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	1.1664595969737745	[296]	[481]	8	hSpCas9	negative selection	11530499
12936353	12936376	3	+	28162770	HEL	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	-0.067133101283574	[210]	[128]	0	hSpCas9	negative selection	11699856
12920503	12920526	3	+	28162770	HEL	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	1.0621152670035383	[165]	[221]	8	hSpCas9	negative selection	11699857
12941688	12941711	3	-	28162770	HEL	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	0.9806084707567406	[71]	[90]	8	hSpCas9	negative selection	11699858
12936622	12936645	3	+	28162770	HEL	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.5944836633931357	[303]	[293]	5	hSpCas9	negative selection	11699859
12936169	12936192	3	+	28162770	HEL	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.2504214092215966	[209]	[159]	2	hSpCas9	negative selection	11699860
12935904	12935927	3	+	28162770	HEL	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	0.6619750508632746	[148]	[150]	5	hSpCas9	negative selection	11699861
12924573	12924596	3	+	28162770	HEL	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	0.01383298369160374	[299]	[193]	0	hSpCas9	negative selection	11699862
12922154	12922177	3	-	28162770	HEL	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	1.1591370462384416	[78]	[112]	8	hSpCas9	negative selection	11699863
12922137	12922160	3	-	28162770	HEL	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	-0.18733616655733076	[111]	[62]	-1	hSpCas9	negative selection	11699864
12920553	12920576	3	+	28162770	HEL	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	-0.26746449764899727	[217]	[115]	-2	hSpCas9	negative selection	11699865
12936353	12936376	3	+	28162770	MV411	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	-0.4444401538548931	[125]	[77]	-3	hSpCas9	negative selection	11869222
12920503	12920526	3	+	28162770	MV411	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	0.16153747737712817	[172]	[162]	1	hSpCas9	negative selection	11869223
12941688	12941711	3	-	28162770	MV411	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	0.8658747560550196	[70]	[108]	7	hSpCas9	negative selection	11869224
12936622	12936645	3	+	28162770	MV411	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.4058669133872581	[223]	[249]	3	hSpCas9	negative selection	11869225
12936169	12936192	3	+	28162770	MV411	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.6184257765656883	[194]	[106]	-4	hSpCas9	negative selection	11869226
12935904	12935927	3	+	28162770	MV411	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	-0.2830771659160045	[77]	[53]	-2	hSpCas9	negative selection	11869227
12924573	12924596	3	+	28162770	MV411	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	0.4065040367503938	[162]	[181]	3	hSpCas9	negative selection	11869228
12922154	12922177	3	-	28162770	MV411	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	0.744937210253592	[50]	[71]	6	hSpCas9	negative selection	11869229
12922137	12922160	3	-	28162770	MV411	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	-0.38779815641960447	[72]	[46]	-3	hSpCas9	negative selection	11869230
12920553	12920576	3	+	28162770	MV411	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	0.05590609315108805	[184]	[161]	0	hSpCas9	negative selection	11869231
12936353	12936376	3	+	28162770	MONOMAC1	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	-0.1464107739895858	[83]	[86]	-1	hSpCas9	negative selection	12038588
12920503	12920526	3	+	28162770	MONOMAC1	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	-0.5708516836118847	[91]	[70]	-5	hSpCas9	negative selection	12038589
12941688	12941711	3	-	28162770	MONOMAC1	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	0.04112289013521098	[38]	[45]	0	hSpCas9	negative selection	12038590
12936622	12936645	3	+	28162770	MONOMAC1	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.04912374020984406	[171]	[203]	0	hSpCas9	negative selection	12038591
12936169	12936192	3	+	28162770	MONOMAC1	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	1.055729223320413	[140]	[335]	8	hSpCas9	negative selection	12038592
12935904	12935927	3	+	28162770	MONOMAC1	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	-1.1181814263483143	[88]	[46]	-7	hSpCas9	negative selection	12038593
12924573	12924596	3	+	28162770	MONOMAC1	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	0.2114279982958039	[109]	[145]	2	hSpCas9	negative selection	12038594
12922154	12922177	3	-	28162770	MONOMAC1	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	1.0094140304078727	[38]	[89]	8	hSpCas9	negative selection	12038595
12922137	12922160	3	-	28162770	MONOMAC1	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	-0.011170301748219646	[79]	[90]	0	hSpCas9	negative selection	12038596
12920553	12920576	3	+	28162770	MONOMAC1	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	0.07661123279909204	[157]	[190]	0	hSpCas9	negative selection	12038597
12936353	12936376	3	+	28162770	OCIAML2	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	-0.7462642678555885	[22]	[75]	-5	hSpCas9	negative selection	12207954
12920503	12920526	3	+	28162770	OCIAML2	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	0.20396988796367124	[25]	[165]	2	hSpCas9	negative selection	12207955
12941688	12941711	3	-	28162770	OCIAML2	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	-0.8856673245210049	[12]	[38]	-6	hSpCas9	negative selection	12207956
12936622	12936645	3	+	28162770	OCIAML2	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.5549052668649762	[48]	[398]	5	hSpCas9	negative selection	12207957
12936169	12936192	3	+	28162770	OCIAML2	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	-0.38476908858832315	[52]	[224]	-3	hSpCas9	negative selection	12207958
12935904	12935927	3	+	28162770	OCIAML2	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	0.09124906236595365	[20]	[123]	0	hSpCas9	negative selection	12207959
12924573	12924596	3	+	28162770	OCIAML2	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.4501657226824457	[34]	[141]	-4	hSpCas9	negative selection	12207960
12922154	12922177	3	-	28162770	OCIAML2	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	-0.8301722119293016	[16]	[52]	-5	hSpCas9	negative selection	12207961
12922137	12922160	3	-	28162770	OCIAML2	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	0.1370527519790785	[20]	[127]	1	hSpCas9	negative selection	12207962
12920553	12920576	3	+	28162770	OCIAML2	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	0.3178660695641271	[32]	[227]	3	hSpCas9	negative selection	12207963
12936353	12936376	3	+	28162770	OCIAML3	viability	GGCGTCCGCAAAGTCACTGGAGG	IQSEC1	ENSG00000144711	-0.45650411657422824	[39]	[87]	-4	hSpCas9	negative selection	12377320
12920503	12920526	3	+	28162770	OCIAML3	viability	GTTCAGCAGGATGATGGCGAAGG	IQSEC1	ENSG00000144711	0.17858186357276457	[35]	[122]	1	hSpCas9	negative selection	12377321
12941688	12941711	3	-	28162770	OCIAML3	viability	GGCAACAGCAGCGCACGCGGAGG	IQSEC1	ENSG00000144711	-0.9501514505494384	[31]	[49]	-6	hSpCas9	negative selection	12377322
12936622	12936645	3	+	28162770	OCIAML3	viability	GAAACGCCGTCTGGATGGTGCGG	IQSEC1	ENSG00000144711	0.308695158320922	[68]	[257]	3	hSpCas9	negative selection	12377323
12936169	12936192	3	+	28162770	OCIAML3	viability	TCATCTCGTCCAGTTTGCGGTGG	IQSEC1	ENSG00000144711	0.011713420563790378	[45]	[139]	0	hSpCas9	negative selection	12377324
12935904	12935927	3	+	28162770	OCIAML3	viability	GGTGGCTCGATGGTGAGCAGCGG	IQSEC1	ENSG00000144711	2.0093333897118475	[25]	[315]	9	hSpCas9	negative selection	12377325
12924573	12924596	3	+	28162770	OCIAML3	viability	GAACTTACTCGAGCACGTCACGG	IQSEC1	ENSG00000144711	-0.0355173509641981	[54]	[161]	0	hSpCas9	negative selection	12377326
12922154	12922177	3	-	28162770	OCIAML3	viability	GCACATCCGTGTCCAAGGGGAGG	IQSEC1	ENSG00000144711	-0.7460107337692128	[14]	[26]	-5	hSpCas9	negative selection	12377327
12922137	12922160	3	-	28162770	OCIAML3	viability	GGGAGGCTCAGAAAGTGGAGCGG	IQSEC1	ENSG00000144711	0.12727633160977336	[36]	[121]	1	hSpCas9	negative selection	12377328
12920553	12920576	3	+	28162770	OCIAML3	viability	GGAATTGCCGCACCACCCCAGGG	IQSEC1	ENSG00000144711	-0.18140918649673665	[73]	[196]	-1	hSpCas9	negative selection	12377329