Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 23096
• Symbol: IQSEC2
• Description: IQ motif and Sec7 domain ArfGEF 2

DataSource: http://genomecrispr.dkfz.de/#!/results/IQSEC2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
53250368	53250391	X	-	26472758	Jiyoye	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	1.7165034396136023	[68]	[170]	8	hSpCas9	negative selection	79029
53250780	53250803	X	+	26472758	Jiyoye	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-0.7468582471665476	[157]	[70]	-5	hSpCas9	negative selection	79030
53255976	53255999	X	+	26472758	Jiyoye	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	0.8256275451974817	[210]	[281]	6	hSpCas9	negative selection	79031
53255926	53255949	X	+	26472758	Jiyoye	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	0.10330725816350217	[257]	[208]	0	hSpCas9	negative selection	79032
53255910	53255933	X	+	26472758	Jiyoye	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.7173049050749685	[220]	[273]	5	hSpCas9	negative selection	79033
53254769	53254792	X	+	26472758	Jiyoye	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.6635151347656592	[323]	[386]	5	hSpCas9	negative selection	79034
53251111	53251134	X	+	26472758	Jiyoye	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	-1.4159468564100472	[91]	[25]	-7	hSpCas9	negative selection	79035
53251057	53251080	X	-	26472758	Jiyoye	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	-0.10012062562495905	[225]	[158]	0	hSpCas9	negative selection	79036
53250900	53250923	X	+	26472758	Jiyoye	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	2.4071753815058727	[0]	[3]	9	hSpCas9	negative selection	79037
53250852	53250875	X	-	26472758	Jiyoye	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.13778548063225593	[181]	[150]	1	hSpCas9	negative selection	79038
53250368	53250391	X	-	26472758	KBM7	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	-0.5470649862399606	[507,339]	[108,156]	-5	hSpCas9	negative selection	270147
53250780	53250803	X	+	26472758	KBM7	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	0.09622208971195917	[388,336]	[181,181]	0	hSpCas9	negative selection	270148
53255976	53255999	X	+	26472758	KBM7	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	-0.9332925860513017	[741,666]	[175,170]	-6	hSpCas9	negative selection	270149
53255926	53255949	X	+	26472758	KBM7	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	-0.34248635487214096	[738,551]	[274,202]	-3	hSpCas9	negative selection	270150
53255910	53255933	X	+	26472758	KBM7	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.09952353545504367	[1280,1089]	[817,395]	1	hSpCas9	negative selection	270151
53254769	53254792	X	+	26472758	KBM7	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.19982063620063029	[1768,1189]	[977,615]	2	hSpCas9	negative selection	270152
53251111	53251134	X	+	26472758	KBM7	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	0.9307819860501915	[198,98]	[32,215]	8	hSpCas9	negative selection	270153
53251057	53251080	X	-	26472758	KBM7	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	-0.2026989049392376	[1142,955]	[389,459]	-2	hSpCas9	negative selection	270154
53250900	53250923	X	+	26472758	KBM7	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-2.6493186123618697	[16,32]	[2,0]	-9	hSpCas9	negative selection	270155
53250852	53250875	X	-	26472758	KBM7	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.05728842465437611	[639,787]	[378,332]	0	hSpCas9	negative selection	270156
53250368	53250391	X	-	26472758	Raji	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	1.288623850043746	[126]	[71]	9	hSpCas9	negative selection	461265
53250780	53250803	X	+	26472758	Raji	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-0.31408023306467747	[149]	[27]	-3	hSpCas9	negative selection	461266
53255976	53255999	X	+	26472758	Raji	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	0.8627611666536862	[326]	[137]	7	hSpCas9	negative selection	461267
53255926	53255949	X	+	26472758	Raji	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	0.4593688641171416	[303]	[96]	4	hSpCas9	negative selection	461268
53255910	53255933	X	+	26472758	Raji	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.33440740544169323	[621]	[181]	3	hSpCas9	negative selection	461269
53254769	53254792	X	+	26472758	Raji	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.30237255378429473	[614]	[175]	3	hSpCas9	negative selection	461270
53251111	53251134	X	+	26472758	Raji	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	-0.6088234986258092	[137]	[20]	-5	hSpCas9	negative selection	461271
53251057	53251080	X	-	26472758	Raji	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	0.14440939235706685	[576]	[147]	1	hSpCas9	negative selection	461272
53250900	53250923	X	+	26472758	Raji	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-2.699971386684005	[27]	[0]	-9	hSpCas9	negative selection	461273
53250852	53250875	X	-	26472758	Raji	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.025933721753857664	[418]	[98]	0	hSpCas9	negative selection	461274
53250368	53250391	X	-	26472758	K562	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	0.1694566699852248	[315]	[299]	1	hSpCas9	negative selection	652383
53250780	53250803	X	+	26472758	K562	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-0.22544279635691866	[294]	[212]	-1	hSpCas9	negative selection	652384
53255976	53255999	X	+	26472758	K562	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	0.07927652259423201	[526]	[469]	0	hSpCas9	negative selection	652385
53255926	53255949	X	+	26472758	K562	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	-0.3644529166631404	[577]	[378]	-2	hSpCas9	negative selection	652386
53255910	53255933	X	+	26472758	K562	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.5744235128764881	[1139]	[1432]	4	hSpCas9	negative selection	652387
53254769	53254792	X	+	26472758	K562	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.6015753108647908	[1245]	[1595]	5	hSpCas9	negative selection	652388
53251111	53251134	X	+	26472758	K562	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	0.9103012237711705	[103]	[164]	7	hSpCas9	negative selection	652389
53251057	53251080	X	-	26472758	K562	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	-1.2431791985454221	[930]	[331]	-6	hSpCas9	negative selection	652390
53250900	53250923	X	+	26472758	K562	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-4.077509367220915	[19]	[0]	-9	hSpCas9	negative selection	652391
53250852	53250875	X	-	26472758	K562	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.24441872766644673	[505]	[505]	1	hSpCas9	negative selection	652392
53248154	53248177	X	+	26627737	DLD1	viability	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	1.1317995425909582	[346]	[260,288,174]	9	hSpCas9	negative selection	846021
53248780	53248803	X	-	26627737	DLD1	viability	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	-1.339648309103684	[262]	[36,37,23]	-8	hSpCas9	negative selection	846022
53250669	53250692	X	-	26627737	DLD1	viability	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.21343479803939314	[684]	[278,213,249]	2	hSpCas9	negative selection	846023
53254685	53254708	X	-	26627737	DLD1	viability	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.19271861133298843	[469]	[145,261,108]	2	hSpCas9	negative selection	846024
53255928	53255951	X	+	26627737	DLD1	viability	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	-0.5035694042539209	[248]	[29,104,34]	-5	hSpCas9	negative selection	846025
53320855	53320878	X	+	26627737	DLD1	viability	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.7323324577046376	[399]	[126,309,192]	7	hSpCas9	negative selection	846026
53248154	53248177	X	+	26627737	GBM cells	viability after 5 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.26456334720236585	[311]	[225,175]	4	hSpCas9	negative selection	928336
53248780	53248803	X	-	26627737	GBM cells	viability after 5 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	-0.4126722757802177	[138]	[38,72]	-6	hSpCas9	negative selection	928337
53250669	53250692	X	-	26627737	GBM cells	viability after 5 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.252706468428299	[402]	[262,251]	4	hSpCas9	negative selection	928338
53254685	53254708	X	-	26627737	GBM cells	viability after 5 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.6107063978423244	[184]	[141,160]	8	hSpCas9	negative selection	928339
53255928	53255951	X	+	26627737	GBM cells	viability after 5 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	-0.32185480397109856	[147]	[64,61]	-5	hSpCas9	negative selection	928340
53320855	53320878	X	+	26627737	GBM cells	viability after 5 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.6996050666622791	[92]	[115,45]	8	hSpCas9	negative selection	928341
53248154	53248177	X	+	26627737	GBM cells	viability after 13 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.5055350001532337	[311]	[268,216]	6	hSpCas9	negative selection	1010651
53248780	53248803	X	-	26627737	GBM cells	viability after 13 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	0.2203014746899431	[138]	[83,90]	3	hSpCas9	negative selection	1010652
53250669	53250692	X	-	26627737	GBM cells	viability after 13 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.41932464174274875	[402]	[362,234]	5	hSpCas9	negative selection	1010653
53254685	53254708	X	-	26627737	GBM cells	viability after 13 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.041644011074483234	[184]	[115,92]	0	hSpCas9	negative selection	1010654
53255928	53255951	X	+	26627737	GBM cells	viability after 13 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.1337680348642868	[147]	[86,88]	1	hSpCas9	negative selection	1010655
53320855	53320878	X	+	26627737	GBM cells	viability after 13 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.622076897291515	[92]	[91,65]	7	hSpCas9	negative selection	1010656
53248154	53248177	X	+	26627737	GBM cells	viability after 21 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.2663131765056963	[311]	[206,200]	2	hSpCas9	negative selection	1092966
53248780	53248803	X	-	26627737	GBM cells	viability after 21 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	0.728614566114507	[138]	[121,127]	7	hSpCas9	negative selection	1092967
53250669	53250692	X	-	26627737	GBM cells	viability after 21 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.36395441005742235	[402]	[298,265]	4	hSpCas9	negative selection	1092968
53254685	53254708	X	-	26627737	GBM cells	viability after 21 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.028019125281604662	[184]	[102,101]	0	hSpCas9	negative selection	1092969
53255928	53255951	X	+	26627737	GBM cells	viability after 21 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.15369990554637558	[147]	[78,98]	1	hSpCas9	negative selection	1092970
53320855	53320878	X	+	26627737	GBM cells	viability after 21 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.7788496752025146	[92]	[93,79]	7	hSpCas9	negative selection	1092971
53248154	53248177	X	+	26627737	RPE1	viability after 9 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	1.7873528148907487	[361]	[457,304]	8	hSpCas9	negative selection	1175281
53248780	53248803	X	-	26627737	RPE1	viability after 9 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	6.11566259258966	[2]	[65,63]	9	hSpCas9	negative selection	1175282
53250669	53250692	X	-	26627737	RPE1	viability after 9 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	1.3197561923484515	[723]	[467,691]	7	hSpCas9	negative selection	1175283
53254685	53254708	X	-	26627737	RPE1	viability after 9 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.22077222191300844	[693]	[226,286]	1	hSpCas9	negative selection	1175284
53255928	53255951	X	+	26627737	RPE1	viability after 9 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	-0.7724098729527191	[687]	[81,182]	-5	hSpCas9	negative selection	1175285
53320855	53320878	X	+	26627737	RPE1	viability after 9 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	1.246219040982678	[353]	[213,325]	7	hSpCas9	negative selection	1175286
53248154	53248177	X	+	26627737	RPE1	viability after 12 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	1.9055315520052967	[361]	[461,260]	8	hSpCas9	negative selection	1257596
53248780	53248803	X	-	26627737	RPE1	viability after 12 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	6.611795635360288	[2]	[89,66]	9	hSpCas9	negative selection	1257597
53250669	53250692	X	-	26627737	RPE1	viability after 12 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	1.2989421112410688	[723]	[481,474]	7	hSpCas9	negative selection	1257598
53254685	53254708	X	-	26627737	RPE1	viability after 12 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.4924721282145267	[693]	[255,268]	3	hSpCas9	negative selection	1257599
53255928	53255951	X	+	26627737	RPE1	viability after 12 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	-0.6700418601291942	[687]	[2,235]	-4	hSpCas9	negative selection	1257600
53320855	53320878	X	+	26627737	RPE1	viability after 12 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	1.3982418356644046	[353]	[273,225]	7	hSpCas9	negative selection	1257601
53248154	53248177	X	+	26627737	RPE1	viability after 15 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	1.2457346090264663	[361]	[223,260]	7	hSpCas9	negative selection	1339911
53248780	53248803	X	-	26627737	RPE1	viability after 15 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	6.917953221294045	[2]	[123,81]	9	hSpCas9	negative selection	1339912
53250669	53250692	X	-	26627737	RPE1	viability after 15 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	1.0673073436218516	[723]	[503,356]	6	hSpCas9	negative selection	1339913
53254685	53254708	X	-	26627737	RPE1	viability after 15 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.36512467970318246	[693]	[260,244]	2	hSpCas9	negative selection	1339914
53255928	53255951	X	+	26627737	RPE1	viability after 15 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	-1.092494976721311	[687]	[19,159]	-6	hSpCas9	negative selection	1339915
53320855	53320878	X	+	26627737	RPE1	viability after 15 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	1.3454086428604954	[353]	[256,251]	7	hSpCas9	negative selection	1339916
53248154	53248177	X	+	26627737	RPE1	viability after 18 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	1.6230558316623367	[361]	[283,318]	8	hSpCas9	negative selection	1422226
53248780	53248803	X	-	26627737	RPE1	viability after 18 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	7.077899664400393	[2]	[134,81]	9	hSpCas9	negative selection	1422227
53250669	53250692	X	-	26627737	RPE1	viability after 18 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	1.3327537338137176	[723]	[539,440]	7	hSpCas9	negative selection	1422228
53254685	53254708	X	-	26627737	RPE1	viability after 18 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.471217870735424	[693]	[248,270]	3	hSpCas9	negative selection	1422229
53255928	53255951	X	+	26627737	RPE1	viability after 18 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	-1.911874654357917	[687]	[0,100]	-8	hSpCas9	negative selection	1422230
53320855	53320878	X	+	26627737	RPE1	viability after 18 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.6904023728788888	[353]	[158,148]	4	hSpCas9	negative selection	1422231
53248154	53248177	X	+	26627737	HeLa	viability after 8 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.03138091720911529	[661]	[293,322,267]	0	hSpCas9	negative selection	1504541
53248780	53248803	X	-	26627737	HeLa	viability after 8 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	0.9341700297616765	[219]	[119,262,153]	7	hSpCas9	negative selection	1504542
53250669	53250692	X	-	26627737	HeLa	viability after 8 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.5508747758595984	[636]	[312,408,470]	5	hSpCas9	negative selection	1504543
53254685	53254708	X	-	26627737	HeLa	viability after 8 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	-0.07821301635562611	[284]	[109,111,127]	0	hSpCas9	negative selection	1504544
53255928	53255951	X	+	26627737	HeLa	viability after 8 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.4554878110676424	[209]	[74,166,122]	4	hSpCas9	negative selection	1504545
53320855	53320878	X	+	26627737	HeLa	viability after 8 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	-0.16943942789953204	[371]	[168,178,92]	-2	hSpCas9	negative selection	1504546
53248154	53248177	X	+	26627737	HeLa	viability after 12 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.5129121597877022	[661]	[496,420,252]	4	hSpCas9	negative selection	1586856
53248780	53248803	X	-	26627737	HeLa	viability after 12 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	0.8326793970644506	[219]	[171,171,140]	6	hSpCas9	negative selection	1586857
53250669	53250692	X	-	26627737	HeLa	viability after 12 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.34553078356955536	[636]	[369,225,419]	3	hSpCas9	negative selection	1586858
53254685	53254708	X	-	26627737	HeLa	viability after 12 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	-0.45662998545799754	[284]	[47,145,55]	-4	hSpCas9	negative selection	1586859
53255928	53255951	X	+	26627737	HeLa	viability after 12 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.394837001991721	[209]	[95,130,112]	3	hSpCas9	negative selection	1586860
53320855	53320878	X	+	26627737	HeLa	viability after 12 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.16883105542769458	[371]	[83,199,228]	1	hSpCas9	negative selection	1586861
53248154	53248177	X	+	26627737	HeLa	viability after 15 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.2492824222788912	[661]	[299,319,342]	2	hSpCas9	negative selection	1669171
53248780	53248803	X	-	26627737	HeLa	viability after 15 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	-0.19552486062837182	[219]	[17,119,98]	-2	hSpCas9	negative selection	1669172
53250669	53250692	X	-	26627737	HeLa	viability after 15 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.38389437173166985	[636]	[197,467,351]	3	hSpCas9	negative selection	1669173
53254685	53254708	X	-	26627737	HeLa	viability after 15 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.14928368513104906	[284]	[205,110,62]	1	hSpCas9	negative selection	1669174
53255928	53255951	X	+	26627737	HeLa	viability after 15 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.44908055144929526	[209]	[212,41,91]	4	hSpCas9	negative selection	1669175
53320855	53320878	X	+	26627737	HeLa	viability after 15 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.26438500304375046	[371]	[174,125,249]	2	hSpCas9	negative selection	1669176
53248154	53248177	X	+	26627737	HeLa	viability after 18 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.2177648119416492	[661]	[186,265,342]	1	hSpCas9	negative selection	1751486
53248780	53248803	X	-	26627737	HeLa	viability after 18 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	-0.22782163251763266	[219]	[12,93,98]	-2	hSpCas9	negative selection	1751487
53250669	53250692	X	-	26627737	HeLa	viability after 18 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.38725637885962483	[636]	[133,387,351]	3	hSpCas9	negative selection	1751488
53254685	53254708	X	-	26627737	HeLa	viability after 18 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.17131782403266116	[284]	[137,96,62]	1	hSpCas9	negative selection	1751489
53255928	53255951	X	+	26627737	HeLa	viability after 18 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.48586159370776255	[209]	[150,31,91]	4	hSpCas9	negative selection	1751490
53320855	53320878	X	+	26627737	HeLa	viability after 18 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.3082200572913152	[371]	[122,110,249]	2	hSpCas9	negative selection	1751491
53248154	53248177	X	+	26627737	HCT116	viability after 6 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	1.478084023921117	[550]	[395,155]	7	hSpCas9	negative selection	1833801
53248780	53248803	X	-	26627737	HCT116	viability after 6 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	0.0982997340685553	[466]	[124,52]	0	hSpCas9	negative selection	1833802
53250669	53250692	X	-	26627737	HCT116	viability after 6 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.05991896935093033	[1026]	[108,200]	0	hSpCas9	negative selection	1833803
53254685	53254708	X	-	26627737	HCT116	viability after 6 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	1.0300895889248656	[506]	[87,203]	5	hSpCas9	negative selection	1833804
53255928	53255951	X	+	26627737	HCT116	viability after 6 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.9302200568735762	[530]	[131,173]	5	hSpCas9	negative selection	1833805
53320855	53320878	X	+	26627737	HCT116	viability after 6 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.4648503816302399	[676]	[133,153]	2	hSpCas9	negative selection	1833806
53248154	53248177	X	+	26627737	HCT116	viability after 8 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	-0.027576598241787098	[358]	[223,184,173]	0	hSpCas9	negative selection	1916116
53248780	53248803	X	-	26627737	HCT116	viability after 8 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	-0.24204884395020576	[91]	[62,26,38]	-3	hSpCas9	negative selection	1916117
53250669	53250692	X	-	26627737	HCT116	viability after 8 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.4027652890424015	[354]	[186,365,221]	4	hSpCas9	negative selection	1916118
53254685	53254708	X	-	26627737	HCT116	viability after 8 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.2585428084219903	[227]	[122,144,181]	3	hSpCas9	negative selection	1916119
53255928	53255951	X	+	26627737	HCT116	viability after 8 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	-0.14906790398287514	[273]	[79,151,174]	-2	hSpCas9	negative selection	1916120
53320855	53320878	X	+	26627737	HCT116	viability after 8 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.33804176134043523	[241]	[124,219,159]	3	hSpCas9	negative selection	1916121
53248154	53248177	X	+	26627737	HCT116	viability after 9 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.5770696100894812	[550]	[190,241]	4	hSpCas9	negative selection	1998431
53248780	53248803	X	-	26627737	HCT116	viability after 9 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	-0.07997635546834098	[466]	[60,162]	0	hSpCas9	negative selection	1998432
53250669	53250692	X	-	26627737	HCT116	viability after 9 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.31432104182477094	[1026]	[364,321]	2	hSpCas9	negative selection	1998433
53254685	53254708	X	-	26627737	HCT116	viability after 9 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.23888101397206934	[506]	[142,172]	1	hSpCas9	negative selection	1998434
53255928	53255951	X	+	26627737	HCT116	viability after 9 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.30874842324984836	[530]	[245,119]	2	hSpCas9	negative selection	1998435
53320855	53320878	X	+	26627737	HCT116	viability after 9 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	-0.30304357872690163	[676]	[131,157]	-2	hSpCas9	negative selection	1998436
53248154	53248177	X	+	26627737	HCT116	viability after 12 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.7178241352832067	[358]	[178,292,469]	6	hSpCas9	negative selection	2080746
53248780	53248803	X	-	26627737	HCT116	viability after 12 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	0.589462644120696	[91]	[113,46,52]	5	hSpCas9	negative selection	2080747
53250669	53250692	X	-	26627737	HCT116	viability after 12 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.39011724044171914	[354]	[195,296,245]	4	hSpCas9	negative selection	2080748
53254685	53254708	X	-	26627737	HCT116	viability after 12 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.7508687241735454	[227]	[292,247,56]	6	hSpCas9	negative selection	2080749
53255928	53255951	X	+	26627737	HCT116	viability after 12 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.0043340612712679805	[273]	[133,94,203]	0	hSpCas9	negative selection	2080750
53320855	53320878	X	+	26627737	HCT116	viability after 12 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.455665207658799	[241]	[211,176,130]	4	hSpCas9	negative selection	2080751
53248154	53248177	X	+	26627737	HCT116	viability after 15 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.29017520189073714	[358]	[288,152,317]	3	hSpCas9	negative selection	2163061
53248780	53248803	X	-	26627737	HCT116	viability after 15 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	0.877570000579821	[91]	[108,113,69]	7	hSpCas9	negative selection	2163062
53250669	53250692	X	-	26627737	HCT116	viability after 15 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.6314393542658612	[354]	[472,210,282]	6	hSpCas9	negative selection	2163063
53254685	53254708	X	-	26627737	HCT116	viability after 15 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.1254788107959982	[227]	[166,166,97]	1	hSpCas9	negative selection	2163064
53255928	53255951	X	+	26627737	HCT116	viability after 15 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.24583843387118623	[273]	[186,200,171]	2	hSpCas9	negative selection	2163065
53320855	53320878	X	+	26627737	HCT116	viability after 15 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.4846199979160418	[241]	[267,184,139]	4	hSpCas9	negative selection	2163066
53248154	53248177	X	+	26627737	HCT116	viability after 18 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.25056324014512016	[358]	[273,113,238]	2	hSpCas9	negative selection	2245376
53248780	53248803	X	-	26627737	HCT116	viability after 18 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	1.265198664336907	[91]	[165,45,112]	8	hSpCas9	negative selection	2245377
53250669	53250692	X	-	26627737	HCT116	viability after 18 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.4103709114410312	[354]	[196,268,214]	3	hSpCas9	negative selection	2245378
53254685	53254708	X	-	26627737	HCT116	viability after 18 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	-0.01796749086584043	[227]	[95,161,62]	0	hSpCas9	negative selection	2245379
53255928	53255951	X	+	26627737	HCT116	viability after 18 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.29033371691822263	[273]	[135,26,339]	2	hSpCas9	negative selection	2245380
53320855	53320878	X	+	26627737	HCT116	viability after 18 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.2258306566005635	[241]	[161,138,107]	2	hSpCas9	negative selection	2245381
53255974	53255997	X	+	24336569	HL60	viability	GGGCAGCTGGCTCAGCCGGTAGG	IQSEC2	ENSG00000124313	0.7375099046955409	[52]	[186]	6	hSpCas9	negative selection	2272026
53256007	53256030	X	-	24336569	HL60	viability	GCACAGCGGTTGATAGTCCTGGG	IQSEC2	ENSG00000124313	0.29113813232955105	[413]	[1071]	2	hSpCas9	negative selection	2272027
53256012	53256035	X	+	24336569	HL60	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.18984026167368806	[151]	[281]	-2	hSpCas9	negative selection	2272028
53256021	53256044	X	-	24336569	HL60	viability	AGGCAGTGACCTGAGCACAGCGG	IQSEC2	ENSG00000124313	-0.2852195917946887	[1377]	[2392]	-3	hSpCas9	negative selection	2272029
53279563	53279586	X	-	24336569	HL60	viability	CAGGCAGGCTGGCAGAGAGCAGG	IQSEC2	ENSG00000124313	-0.5523548346412577	[947]	[1367]	-5	hSpCas9	negative selection	2272030
53279589	53279612	X	+	24336569	HL60	viability	GGGTAAGCTTCATGGAGTCAAGG	IQSEC2	ENSG00000124313	-0.8221790435867194	[898]	[1075]	-6	hSpCas9	negative selection	2272031
53279600	53279623	X	+	24336569	HL60	viability	ATGGAGTCAAGGACCTGAGTAGG	IQSEC2	ENSG00000124313	-0.46848722373814367	[169]	[259]	-4	hSpCas9	negative selection	2272032
53279613	53279636	X	+	24336569	HL60	viability	CCTGAGTAGGACAGCAATACTGG	IQSEC2	ENSG00000124313	0.12961822557017566	[1243]	[2879]	1	hSpCas9	negative selection	2272033
53279635	53279658	X	+	24336569	HL60	viability	GTGTAGAGTATGAGACGCTGTGG	IQSEC2	ENSG00000124313	-0.41136046085876293	[816]	[1299]	-4	hSpCas9	negative selection	2272034
53281489	53281512	X	+	24336569	HL60	viability	TTCCTACCTGCTGCTCCTCCCGG	IQSEC2	ENSG00000124313	0.6139223897859103	[263]	[854]	5	hSpCas9	negative selection	2272035
53255974	53255997	X	+	24336569	KBM7	viability	GGGCAGCTGGCTCAGCCGGTAGG	IQSEC2	ENSG00000124313	4.506617113837994	[0]	[61]	9	hSpCas9	negative selection	2339203
53256007	53256030	X	-	24336569	KBM7	viability	GCACAGCGGTTGATAGTCCTGGG	IQSEC2	ENSG00000124313	0.7186475330889803	[216]	[973]	6	hSpCas9	negative selection	2339204
53256012	53256035	X	+	24336569	KBM7	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.18177742353072723	[31]	[98]	1	hSpCas9	negative selection	2339205
53256021	53256044	X	-	24336569	KBM7	viability	AGGCAGTGACCTGAGCACAGCGG	IQSEC2	ENSG00000124313	0.3747119958135925	[905]	[3203]	3	hSpCas9	negative selection	2339206
53279563	53279586	X	-	24336569	KBM7	viability	CAGGCAGGCTGGCAGAGAGCAGG	IQSEC2	ENSG00000124313	0.020921252626712294	[691]	[1914]	0	hSpCas9	negative selection	2339207
53279589	53279612	X	+	24336569	KBM7	viability	GGGTAAGCTTCATGGAGTCAAGG	IQSEC2	ENSG00000124313	-0.306223347303341	[407]	[899]	-3	hSpCas9	negative selection	2339208
53279600	53279623	X	+	24336569	KBM7	viability	ATGGAGTCAAGGACCTGAGTAGG	IQSEC2	ENSG00000124313	1.0819443177468475	[83]	[484]	8	hSpCas9	negative selection	2339209
53279613	53279636	X	+	24336569	KBM7	viability	CCTGAGTAGGACAGCAATACTGG	IQSEC2	ENSG00000124313	-0.010630308566988322	[1069]	[2896]	0	hSpCas9	negative selection	2339210
53279635	53279658	X	+	24336569	KBM7	viability	GTGTAGAGTATGAGACGCTGTGG	IQSEC2	ENSG00000124313	-0.7237889911304095	[395]	[653]	-5	hSpCas9	negative selection	2339211
53281489	53281512	X	+	24336569	KBM7	viability	TTCCTACCTGCTGCTCCTCCCGG	IQSEC2	ENSG00000124313	-0.49064791844076855	[441]	[857]	-4	hSpCas9	negative selection	2339212
53245890	53245913	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGCTCTGTCACTCAGGCTGG	IQSEC2	ENSG00000124313	-0.9680761470245136	[202,921]	[9,121]	-5	dCas9-VP64	positive selection	2407079
53281730	53281753	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGGGACTGTGAGCTCTCCAGG	IQSEC2	ENSG00000124313	2.1425548728390664	[593,372]	[622,302]	7	dCas9-VP64	positive selection	2445266
53281701	53281724	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCTGGGAACTCCTCCTCCGAGG	IQSEC2	ENSG00000124313	5.876907430537584	[99,49]	[1872,2]	9	dCas9-VP64	positive selection	2445267
53281778	53281801	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCTAGCAGAGGTGCACTGAGGG	IQSEC2	ENSG00000124313	-0.704759959582018	[42,40]	[7,1]	-4	dCas9-VP64	positive selection	2445268
53245890	53245913	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGCTCTGTCACTCAGGCTGG	IQSEC2	ENSG00000124313	-0.6011121662635273	[131,74]	[29,13]	-6	dCas9-VP64	positive selection	2502334
53281730	53281753	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGGGACTGTGAGCTCTCCAGG	IQSEC2	ENSG00000124313	0.5263945446771969	[103,155]	[66,54]	4	dCas9-VP64	positive selection	2540521
53281701	53281724	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCTGGGAACTCCTCCTCCGAGG	IQSEC2	ENSG00000124313	-0.3021561083606138	[172,105]	[59,14]	-3	dCas9-VP64	positive selection	2540522
53281778	53281801	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCTAGCAGAGGTGCACTGAGGG	IQSEC2	ENSG00000124313	2.0401839716389603	[44,131]	[224,17]	8	dCas9-VP64	positive selection	2540523
53256021	53256044	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGCAGTGACCTGAGCACAGCGG	IQSEC2	ENSG00000124313	0.09434868248406325	[4,4]	[4,4]	2	hSpCas9	positive selection	2995895
53254824	53254847	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATGAACAAGAACTTTGAGCGG	IQSEC2	ENSG00000124313	0.23293403507141264	[4,4]	[4,4]	5	hSpCas9	positive selection	2995896
53254704	53254727	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTGCCCTCGAAGTACGCGGGG	IQSEC2	ENSG00000124313	0.4249335388170564	[4,3]	[3,5]	8	hSpCas9	positive selection	2995897
53250781	53250804	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	0.13468333741790406	[3,3]	[2,3]	3	hSpCas9	positive selection	2995898
53256021	53256044	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGCAGTGACCTGAGCACAGCGG	IQSEC2	ENSG00000124313	0.2883734550227164	[4,4]	[3,4]	5	hSpCas9	positive selection	3063753
53254824	53254847	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATGAACAAGAACTTTGAGCGG	IQSEC2	ENSG00000124313	0.05067513681876151	[4,4]	[4,2]	0	hSpCas9	positive selection	3063754
53254704	53254727	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTGCCCTCGAAGTACGCGGGG	IQSEC2	ENSG00000124313	-0.0035781638541370064	[4,4]	[4,1]	0	hSpCas9	positive selection	3063755
53250781	53250804	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-0.18515031967393936	[3,3]	[1,1]	-3	hSpCas9	positive selection	3063756
53254709	53254732		-	24336571	A375	resistance to PLX after 7 days	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.029602146987816984	[11,12]	[12,11]	1	hSpCas9	positive selection	3121526
53255823	53255846		+	24336571	A375	resistance to PLX after 7 days	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-9.871964941510214e-06	[28,28]	[29,27]	0	hSpCas9	positive selection	3121527
53254701	53254724		+	24336571	A375	resistance to PLX after 7 days	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	-0.28142135077653596	[34,31]	[27,26]	-8	hSpCas9	positive selection	3121528
53256012	53256035		+	24336571	A375	resistance to PLX after 7 days	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-3.199001299891702e-05	[24,22]	[22,24]	0	hSpCas9	positive selection	3121530
53254709	53254732		-	24336571	A375	resistance to PLX after 14 days	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.07230408830111715	[10,14]	[3,6]	0	hSpCas9	positive selection	3179319
53255823	53255846		+	24336571	A375	resistance to PLX after 14 days	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	5.070391032012136	[28,26]	[486,404]	9	hSpCas9	positive selection	3179320
53254701	53254724		+	24336571	A375	resistance to PLX after 14 days	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	-0.8568670377439249	[32,27]	[6,7]	-8	hSpCas9	positive selection	3179321
53256012	53256035		+	24336571	A375	resistance to PLX after 14 days	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.6395547340749412	[20,23]	[15,15]	6	hSpCas9	positive selection	3179323
53254709	53254732		-	24336571	A375	viability after 7 days	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.21449194601348182	[14]	[11,12]	-3	hSpCas9	negative selection	3237112
53255823	53255846		+	24336571	A375	viability after 7 days	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.23923736141907637	[25]	[28,28]	3	hSpCas9	negative selection	3237113
53254701	53254724		+	24336571	A375	viability after 7 days	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.5874789986497848	[23]	[34,31]	8	hSpCas9	negative selection	3237114
53256012	53256035		+	24336571	A375	viability after 7 days	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.4206158589641595	[18]	[24,22]	6	hSpCas9	negative selection	3237116
53254709	53254732		-	24336571	A375	viability after 14 days	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.10400696731426363	[14]	[10,14]	-1	hSpCas9	negative selection	3294905
53255823	53255846		+	24336571	A375	viability after 14 days	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.19705497271961847	[25]	[28,26]	2	hSpCas9	negative selection	3294906
53254701	53254724		+	24336571	A375	viability after 14 days	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.4457316693075466	[23]	[32,27]	5	hSpCas9	negative selection	3294907
53256012	53256035		+	24336571	A375	viability after 14 days	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.3244145272199715	[18]	[20,23]	4	hSpCas9	negative selection	3294909
53254709	53254732	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.16986337019549572	[135,135]	[0,0]	0	hSpCas9	positive selection	3374577
53255823	53255846	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.44311350669525723	[207,207]	[0,0]	-3	hSpCas9	positive selection	3374578
53256012	53256035	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.4569193062202875	[209,209]	[0,0]	-3	hSpCas9	positive selection	3374579
53256021	53256044	X	-	26780180	HT29	viability (Avana library 4 designs)	AGGCAGTGACCTGAGCACAGCGG	IQSEC2	ENSG00000124313	0.562898742023305	[]	[]	2	hSpCas9	negative selection	3433284
53254824	53254847	X	-	26780180	HT29	viability (Avana library 4 designs)	GCATGAACAAGAACTTTGAGCGG	IQSEC2	ENSG00000124313	0.648679268916961	[]	[]	2	hSpCas9	negative selection	3433285
53254703	53254726	X	+	26780180	HT29	viability (Avana library 4 designs)	GCTTGCCCTCGAAGTACGCGGGG	IQSEC2	ENSG00000124313	0.0321856204765616	[]	[]	0	hSpCas9	negative selection	3433286
53250780	53250803	X	+	26780180	HT29	viability (Avana library 4 designs)	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	1.18820901216395	[]	[]	4	hSpCas9	negative selection	3433287
53254703	53254726	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTGCCCTCGAAGTACGCGGGG	IQSEC2	ENSG00000124313	-1.66723278644695	[]	[]	-2	hSpCas9	negative selection	3519819
53254824	53254847	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATGAACAAGAACTTTGAGCGG	IQSEC2	ENSG00000124313	0.379086927377961	[]	[]	0	hSpCas9	negative selection	3519820
53250780	53250803	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	6.5071110155898	[]	[]	9	hSpCas9	negative selection	3519821
53256021	53256044	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGCAGTGACCTGAGCACAGCGG	IQSEC2	ENSG00000124313	3.85066780402943	[]	[]	6	hSpCas9	negative selection	3519822
53254644	53254667	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGCCACCGGCTTGAACGGGGG	IQSEC2	ENSG00000124313	-6.87403287853373	[]	[]	-6	hSpCas9	negative selection	3519823
53250730	53250753	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGACAGAGCCGCGATCTGAGCGG	IQSEC2	ENSG00000124313	3.04196875050506	[]	[]	5	hSpCas9	negative selection	3519824
53254703	53254726	X	+	26780180	A375	viability (Avana lentiGuide)	GCTTGCCCTCGAAGTACGCGGGG	IQSEC2	ENSG00000124313	-0.13939214365754	[]	[]	0	hSpCas9	negative selection	3628478
53254824	53254847	X	-	26780180	A375	viability (Avana lentiGuide)	GCATGAACAAGAACTTTGAGCGG	IQSEC2	ENSG00000124313	-5.49892592666687	[]	[]	-8	hSpCas9	negative selection	3628479
53250780	53250803	X	+	26780180	A375	viability (Avana lentiGuide)	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-6.06033951320766	[]	[]	-8	hSpCas9	negative selection	3628480
53256021	53256044	X	-	26780180	A375	viability (Avana lentiGuide)	AGGCAGTGACCTGAGCACAGCGG	IQSEC2	ENSG00000124313	-0.0531310246563244	[]	[]	0	hSpCas9	negative selection	3628481
53254644	53254667	X	-	26780180	A375	viability (Avana lentiGuide)	GGAGCCACCGGCTTGAACGGGGG	IQSEC2	ENSG00000124313	1.44968420495252	[]	[]	1	hSpCas9	negative selection	3628482
53250730	53250753	X	+	26780180	A375	viability (Avana lentiGuide)	GGACAGAGCCGCGATCTGAGCGG	IQSEC2	ENSG00000124313	-0.421757334800812	[]	[]	0	hSpCas9	negative selection	3628483
53254703	53254726	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTGCCCTCGAAGTACGCGGGG	IQSEC2	ENSG00000124313	-0.2965069793420897	[5]	[3,3]	-4	hSpCas9	positive selection	3737137
53254824	53254847	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATGAACAAGAACTTTGAGCGG	IQSEC2	ENSG00000124313	-0.15905038708040356	[5]	[5,4]	-3	hSpCas9	positive selection	3737138
53250780	53250803	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	0.5169465006279363	[4]	[4,7]	9	hSpCas9	positive selection	3737139
53256021	53256044	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGCAGTGACCTGAGCACAGCGG	IQSEC2	ENSG00000124313	0.29237886419715464	[5]	[6,7]	8	hSpCas9	positive selection	3737140
53254644	53254667	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGCCACCGGCTTGAACGGGGG	IQSEC2	ENSG00000124313	-0.3437155960785686	[5]	[4,3]	-5	hSpCas9	positive selection	3737141
53250730	53250753	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACAGAGCCGCGATCTGAGCGG	IQSEC2	ENSG00000124313	0.21311836395631384	[4]	[5,5]	6	hSpCas9	positive selection	3737142
53254703	53254726	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTGCCCTCGAAGTACGCGGGG	IQSEC2	ENSG00000124313	0.03492731758912157	[6]	[4,5]	0	hSpCas9	positive selection	3845744
53254824	53254847	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATGAACAAGAACTTTGAGCGG	IQSEC2	ENSG00000124313	0.25028199994282097	[6]	[7,5]	6	hSpCas9	positive selection	3845745
53250780	53250803	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-0.3492798071496971	[4]	[0,4]	-4	hSpCas9	positive selection	3845746
53256021	53256044	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGCAGTGACCTGAGCACAGCGG	IQSEC2	ENSG00000124313	0.09780061768470566	[6]	[6,6]	2	hSpCas9	positive selection	3845747
53254644	53254667	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGCCACCGGCTTGAACGGGGG	IQSEC2	ENSG00000124313	0.13746756494838125	[6]	[5,5]	3	hSpCas9	positive selection	3845748
53250730	53250753	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACAGAGCCGCGATCTGAGCGG	IQSEC2	ENSG00000124313	-0.4458548784799309	[5]	[2,3]	-5	hSpCas9	positive selection	3845749
53254709	53254732	X	-	26780180	A375	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.755188233352917	[]	[]	3	hSpCas9	negative selection	3951760
53255823	53255846	X	+	26780180	A375	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	1.33510603871451	[]	[]	7	hSpCas9	negative selection	3951761
53254701	53254724	X	+	26780180	A375	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.855318519601412	[]	[]	3	hSpCas9	negative selection	3951762
53241875	53241898	X	+	26780180	A375	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	0.921824203112606	[]	[]	4	hSpCas9	negative selection	3951763
53256012	53256035	X	+	26780180	A375	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	1.76212896607474	[]	[]	9	hSpCas9	negative selection	3951764
53241882	53241905	X	-	26780180	A375	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.0288425756517808	[]	[]	0	hSpCas9	negative selection	3951765
53254709	53254732	X	-	26780180	HT29	viability (GeCKOv2 library)	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	1.70242309369704	[]	[]	8	hSpCas9	negative selection	4059726
53255823	53255846	X	+	26780180	HT29	viability (GeCKOv2 library)	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	1.53924579918597	[]	[]	7	hSpCas9	negative selection	4059727
53254701	53254724	X	+	26780180	HT29	viability (GeCKOv2 library)	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.454275570581771	[]	[]	1	hSpCas9	negative selection	4059728
53241875	53241898	X	+	26780180	HT29	viability (GeCKOv2 library)	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	1.89873822467299	[]	[]	9	hSpCas9	negative selection	4059729
53256012	53256035	X	+	26780180	HT29	viability (GeCKOv2 library)	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	2.06472805603988	[]	[]	9	hSpCas9	negative selection	4059730
53241882	53241905	X	-	26780180	HT29	viability (GeCKOv2 library)	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.0151191508731093	[]	[]	0	hSpCas9	negative selection	4059731
53254709	53254732	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.012325093545512845	[3]	[2,2]	0	hSpCas9	positive selection	4145220
53255823	53255846	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.7693634924980177	[4]	[3,8]	9	hSpCas9	positive selection	4145221
53254701	53254724	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	-0.06340100029302867	[4]	[2,2]	-1	hSpCas9	positive selection	4145222
53256012	53256035	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.2908051324546531	[3]	[2,3]	7	hSpCas9	positive selection	4145224
53254709	53254732	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	1.0411068227514548	[4]	[4,3,4,3]	7	hSpCas9	positive selection	4209242
53255823	53255846	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	1.2054579338139102	[4]	[3,4,1,5]	8	hSpCas9	positive selection	4209243
53254701	53254724	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	1.2399872345968408	[4]	[3,2,5,4]	8	hSpCas9	positive selection	4209244
53256012	53256035	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.2142130883537391	[5]	[5,1,1,0]	-3	hSpCas9	positive selection	4209246
53254701	53254724	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	-0.1295337655934115	[2]	[3,0]	-3	hSpCas9	positive selection	4277223
53241882	53241905	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.4683932931993915	[3]	[4,3]	8	hSpCas9	positive selection	4277224
53241875	53241898	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.12510867772478595	[3]	[2,1]	-2	hSpCas9	positive selection	4277225
53254709	53254732	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.12896860168444513	[3]	[3,1]	-3	hSpCas9	positive selection	4341479
53255823	53255846	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.28505661489059375	[3]	[2,1]	-5	hSpCas9	positive selection	4341480
53256012	53256035	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.5705504840346676	[3]	[1,0]	-8	hSpCas9	positive selection	4341481
53254633	53254655	X	-	27760321	OCIAML3	viability	TTGAACGGGGGCTCCCATATGG	IQSEC2	ENSG00000124313	0.35407551209209587	[193,191]	[222,154]	4	hSpCas9	negative selection	4410210
53254703	53254725	X	+	27760321	OCIAML3	viability	GCTTGCCCTCGAAGTACGCGGG	IQSEC2	ENSG00000124313	0.04054216841958502	[786,655]	[593,556]	0	hSpCas9	negative selection	4410211
53254840	53254862	X	+	27760321	OCIAML3	viability	TTCATGCGGTACTGGCGGAAGG	IQSEC2	ENSG00000124313	0.6419962052567093	[590,522]	[540,857]	7	hSpCas9	negative selection	4410212
53255824	53255846	X	+	27760321	OCIAML3	viability	GAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.4264680254688425	[677,564]	[324,405]	-4	hSpCas9	negative selection	4410213
53250740	53250762	X	+	27760321	OCIAML3	viability	GCGATCTGAGCGGTCACTCAGG	IQSEC2	ENSG00000124313	-0.42305085892335426	[718,589]	[372,388]	-4	hSpCas9	negative selection	4410214
53254633	53254655	X	-	27760321	OCIAML2	viability	TTGAACGGGGGCTCCCATATGG	IQSEC2	ENSG00000124313	0.18629009529610974	[193,191]	[175,180]	2	hSpCas9	negative selection	4493673
53254703	53254725	X	+	27760321	OCIAML2	viability	GCTTGCCCTCGAAGTACGCGGG	IQSEC2	ENSG00000124313	0.4362631525677625	[786,655]	[697,902]	6	hSpCas9	negative selection	4493674
53254840	53254862	X	+	27760321	OCIAML2	viability	TTCATGCGGTACTGGCGGAAGG	IQSEC2	ENSG00000124313	0.60042470998804	[590,522]	[599,789]	7	hSpCas9	negative selection	4493675
53255824	53255846	X	+	27760321	OCIAML2	viability	GAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.016116005737755124	[677,564]	[416,597]	0	hSpCas9	negative selection	4493676
53250740	53250762	X	+	27760321	OCIAML2	viability	GCGATCTGAGCGGTCACTCAGG	IQSEC2	ENSG00000124313	0.6177291736724683	[718,589]	[729,911]	8	hSpCas9	negative selection	4493677
53254633	53254655	X	-	27760321	MV411	viability	TTGAACGGGGGCTCCCATATGG	IQSEC2	ENSG00000124313	0.6471148887170868	[193,191]	[225,160]	5	hSpCas9	negative selection	4577136
53254703	53254725	X	+	27760321	MV411	viability	GCTTGCCCTCGAAGTACGCGGG	IQSEC2	ENSG00000124313	0.3358823621929219	[786,655]	[631,547]	2	hSpCas9	negative selection	4577137
53254840	53254862	X	+	27760321	MV411	viability	TTCATGCGGTACTGGCGGAAGG	IQSEC2	ENSG00000124313	0.8482359361388495	[590,522]	[399,1051]	6	hSpCas9	negative selection	4577138
53255824	53255846	X	+	27760321	MV411	viability	GAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.7121571715692162	[677,564]	[531,874]	5	hSpCas9	negative selection	4577139
53250740	53250762	X	+	27760321	MV411	viability	GCGATCTGAGCGGTCACTCAGG	IQSEC2	ENSG00000124313	0.8246595330215268	[718,589]	[614,980]	6	hSpCas9	negative selection	4577140
53254633	53254655	X	-	27760321	HL60	viability	TTGAACGGGGGCTCCCATATGG	IQSEC2	ENSG00000124313	1.355698923637767	[193,191]	[292,522]	9	hSpCas9	negative selection	4660599
53254703	53254725	X	+	27760321	HL60	viability	GCTTGCCCTCGAAGTACGCGGG	IQSEC2	ENSG00000124313	0.48123624964367084	[786,655]	[845,790]	6	hSpCas9	negative selection	4660600
53254840	53254862	X	+	27760321	HL60	viability	TTCATGCGGTACTGGCGGAAGG	IQSEC2	ENSG00000124313	0.6025206201489923	[590,522]	[545,841]	7	hSpCas9	negative selection	4660601
53255824	53255846	X	+	27760321	HL60	viability	GAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.6377373091604713	[677,564]	[872,694]	7	hSpCas9	negative selection	4660602
53250740	53250762	X	+	27760321	HL60	viability	GCGATCTGAGCGGTCACTCAGG	IQSEC2	ENSG00000124313	-0.053088237533934435	[718,589]	[391,640]	0	hSpCas9	negative selection	4660603
53254633	53254655	X	-	27760321	HT1080	viability	TTGAACGGGGGCTCCCATATGG	IQSEC2	ENSG00000124313	2.9074770184159044	[191,149]	[429,599]	9	hSpCas9	negative selection	4744062
53254703	53254725	X	+	27760321	HT1080	viability	GCTTGCCCTCGAAGTACGCGGG	IQSEC2	ENSG00000124313	1.6618794733238378	[655,511]	[1234,189]	8	hSpCas9	negative selection	4744063
53254840	53254862	X	+	27760321	HT1080	viability	TTCATGCGGTACTGGCGGAAGG	IQSEC2	ENSG00000124313	1.800555497980848	[522,407]	[655,634]	8	hSpCas9	negative selection	4744064
53255824	53255846	X	+	27760321	HT1080	viability	GAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	1.2970735337388362	[564,440]	[426,563]	7	hSpCas9	negative selection	4744065
53250740	53250762	X	+	27760321	HT1080	viability	GCGATCTGAGCGGTCACTCAGG	IQSEC2	ENSG00000124313	-2.083270707009974	[589,460]	[78,16]	-6	hSpCas9	negative selection	4744066
53254633	53254655	X	-	27760321	HT29	viability after 7 days	TTGAACGGGGGCTCCCATATGG	IQSEC2	ENSG00000124313	0.7970492642088407	[191,149]	[374,242,521]	9	hSpCas9	negative selection	4827525
53254703	53254725	X	+	27760321	HT29	viability after 7 days	GCTTGCCCTCGAAGTACGCGGG	IQSEC2	ENSG00000124313	0.21942896046513294	[655,511]	[1006,654,974]	3	hSpCas9	negative selection	4827526
53254840	53254862	X	+	27760321	HT29	viability after 7 days	TTCATGCGGTACTGGCGGAAGG	IQSEC2	ENSG00000124313	0.06440574155478951	[522,407]	[807,484,609]	1	hSpCas9	negative selection	4827527
53255824	53255846	X	+	27760321	HT29	viability after 7 days	GAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.5332920207899225	[564,440]	[615,958,1177]	7	hSpCas9	negative selection	4827528
53250740	53250762	X	+	27760321	HT29	viability after 7 days	GCGATCTGAGCGGTCACTCAGG	IQSEC2	ENSG00000124313	-0.14985145110431297	[589,460]	[826,316,709]	-2	hSpCas9	negative selection	4827529
53254633	53254655	X	-	27760321	HT29	viability after 25 days	TTGAACGGGGGCTCCCATATGG	IQSEC2	ENSG00000124313	-0.6457415142950207	[191,149]	[69,165,143]	-5	hSpCas9	negative selection	4910988
53254703	53254725	X	+	27760321	HT29	viability after 25 days	GCTTGCCCTCGAAGTACGCGGG	IQSEC2	ENSG00000124313	-0.21983444868002922	[655,511]	[652,584,463]	-2	hSpCas9	negative selection	4910989
53254840	53254862	X	+	27760321	HT29	viability after 25 days	TTCATGCGGTACTGGCGGAAGG	IQSEC2	ENSG00000124313	-0.12026466403821984	[522,407]	[632,434,378]	-1	hSpCas9	negative selection	4910990
53255824	53255846	X	+	27760321	HT29	viability after 25 days	GAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.2736348859571935	[564,440]	[669,635,788]	3	hSpCas9	negative selection	4910991
53250740	53250762	X	+	27760321	HT29	viability after 25 days	GCGATCTGAGCGGTCACTCAGG	IQSEC2	ENSG00000124313	-0.1802819085952702	[589,460]	[646,395,539]	-2	hSpCas9	negative selection	4910992
53254633	53254655	X	-	27760321	HT29	viability after 22 days	TTGAACGGGGGCTCCCATATGG	IQSEC2	ENSG00000124313	0.06831724224268476	[191,149]	[230,203,185]	0	hSpCas9	negative selection	4994451
53254703	53254725	X	+	27760321	HT29	viability after 22 days	GCTTGCCCTCGAAGTACGCGGG	IQSEC2	ENSG00000124313	-0.06856194954937889	[655,511]	[794,622,507]	0	hSpCas9	negative selection	4994452
53254840	53254862	X	+	27760321	HT29	viability after 22 days	TTCATGCGGTACTGGCGGAAGG	IQSEC2	ENSG00000124313	-0.05172737442090086	[522,407]	[669,512,368]	0	hSpCas9	negative selection	4994453
53255824	53255846	X	+	27760321	HT29	viability after 22 days	GAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.25947935511224424	[564,440]	[740,648,696]	2	hSpCas9	negative selection	4994454
53250740	53250762	X	+	27760321	HT29	viability after 22 days	GCGATCTGAGCGGTCACTCAGG	IQSEC2	ENSG00000124313	0.1569813198301011	[589,460]	[724,611,693]	1	hSpCas9	negative selection	4994455
53254633	53254655	X	-	27760321	HT29	viability after 19 days	TTGAACGGGGGCTCCCATATGG	IQSEC2	ENSG00000124313	-0.22989627240390664	[191,149]	[111,229,152]	-2	hSpCas9	negative selection	5077914
53254703	53254725	X	+	27760321	HT29	viability after 19 days	GCTTGCCCTCGAAGTACGCGGG	IQSEC2	ENSG00000124313	0.0005025015255419873	[655,511]	[779,736,504]	0	hSpCas9	negative selection	5077915
53254840	53254862	X	+	27760321	HT29	viability after 19 days	TTCATGCGGTACTGGCGGAAGG	IQSEC2	ENSG00000124313	-0.5694748044597884	[522,407]	[601,369,137]	-5	hSpCas9	negative selection	5077916
53255824	53255846	X	+	27760321	HT29	viability after 19 days	GAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.7058103811530678	[564,440]	[765,1299,737]	7	hSpCas9	negative selection	5077917
53250740	53250762	X	+	27760321	HT29	viability after 19 days	GCGATCTGAGCGGTCACTCAGG	IQSEC2	ENSG00000124313	0.32113884359354883	[589,460]	[563,954,714]	3	hSpCas9	negative selection	5077918
53254633	53254655	X	-	27760321	HT29	viability after 16 days	TTGAACGGGGGCTCCCATATGG	IQSEC2	ENSG00000124313	-0.8602254055924132	[191,149]	[153,57,109]	-6	hSpCas9	negative selection	5161377
53254703	53254725	X	+	27760321	HT29	viability after 16 days	GCTTGCCCTCGAAGTACGCGGG	IQSEC2	ENSG00000124313	0.25709880685639697	[655,511]	[933,813,607]	3	hSpCas9	negative selection	5161378
53254840	53254862	X	+	27760321	HT29	viability after 16 days	TTCATGCGGTACTGGCGGAAGG	IQSEC2	ENSG00000124313	0.16975791159303932	[522,407]	[635,857,260]	1	hSpCas9	negative selection	5161379
53255824	53255846	X	+	27760321	HT29	viability after 16 days	GAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.28173381438190676	[564,440]	[538,666,832]	3	hSpCas9	negative selection	5161380
53250740	53250762	X	+	27760321	HT29	viability after 16 days	GCGATCTGAGCGGTCACTCAGG	IQSEC2	ENSG00000124313	-0.5241494282822925	[589,460]	[353,497,366]	-5	hSpCas9	negative selection	5161381
53254633	53254655	X	-	27760321	HT29	viability after 13 days	TTGAACGGGGGCTCCCATATGG	IQSEC2	ENSG00000124313	-0.33947545624538167	[191,149]	[219,106,143]	-4	hSpCas9	negative selection	5244840
53254703	53254725	X	+	27760321	HT29	viability after 13 days	GCTTGCCCTCGAAGTACGCGGG	IQSEC2	ENSG00000124313	-0.08081823998923177	[655,511]	[665,689,569]	-1	hSpCas9	negative selection	5244841
53254840	53254862	X	+	27760321	HT29	viability after 13 days	TTCATGCGGTACTGGCGGAAGG	IQSEC2	ENSG00000124313	0.16736895699833043	[522,407]	[954,522,355]	2	hSpCas9	negative selection	5244842
53255824	53255846	X	+	27760321	HT29	viability after 13 days	GAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.16447909458869175	[564,440]	[410,593,554]	-2	hSpCas9	negative selection	5244843
53250740	53250762	X	+	27760321	HT29	viability after 13 days	GCGATCTGAGCGGTCACTCAGG	IQSEC2	ENSG00000124313	0.07574054465093782	[589,460]	[438,948,545]	0	hSpCas9	negative selection	5244844
53254633	53254655	X	-	27760321	HT29	viability after 10 days	TTGAACGGGGGCTCCCATATGG	IQSEC2	ENSG00000124313	0.1453854904302485	[191,149]	[264,334,113]	2	hSpCas9	negative selection	5328303
53254703	53254725	X	+	27760321	HT29	viability after 10 days	GCTTGCCCTCGAAGTACGCGGG	IQSEC2	ENSG00000124313	0.08568014395996426	[655,511]	[818,889,618]	1	hSpCas9	negative selection	5328304
53254840	53254862	X	+	27760321	HT29	viability after 10 days	TTCATGCGGTACTGGCGGAAGG	IQSEC2	ENSG00000124313	-0.4306600241743932	[522,407]	[618,396,279]	-5	hSpCas9	negative selection	5328305
53255824	53255846	X	+	27760321	HT29	viability after 10 days	GAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.016373641962795393	[564,440]	[625,769,515]	0	hSpCas9	negative selection	5328306
53250740	53250762	X	+	27760321	HT29	viability after 10 days	GCGATCTGAGCGGTCACTCAGG	IQSEC2	ENSG00000124313	0.380158927448646	[589,460]	[770,974,819]	5	hSpCas9	negative selection	5328307
53254633	53254655	X	-	27760321	MOLM13	viability	TTGAACGGGGGCTCCCATATGG	IQSEC2	ENSG00000124313	-0.5047684694261834	[193,191]	[137,24]	-3	hSpCas9	negative selection	5411766
53254703	53254725	X	+	27760321	MOLM13	viability	GCTTGCCCTCGAAGTACGCGGG	IQSEC2	ENSG00000124313	0.9319533718882609	[786,655]	[478,1023]	6	hSpCas9	negative selection	5411767
53254840	53254862	X	+	27760321	MOLM13	viability	TTCATGCGGTACTGGCGGAAGG	IQSEC2	ENSG00000124313	0.7630498731617276	[590,522]	[748,347]	5	hSpCas9	negative selection	5411768
53255824	53255846	X	+	27760321	MOLM13	viability	GAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.2903393005783028	[677,564]	[345,495]	2	hSpCas9	negative selection	5411769
53250740	53250762	X	+	27760321	MOLM13	viability	GCGATCTGAGCGGTCACTCAGG	IQSEC2	ENSG00000124313	-0.2993174624180179	[718,589]	[511,116]	-2	hSpCas9	negative selection	5411770
53320898	53320921	X	+	27661255	K562	viability	GGTCCCGGTGCAGCTCCCCGCGG	IQSEC2	ENSG00000124313	-0.005554491956157648	[1300,1265]	[1118,938]	0	dCas9-KRAB	negative selection	5487145
53321268	53321291	X	+	27661255	K562	viability	GGGCCCGGGAGACAGCGCTGGGG	IQSEC2	ENSG00000124313	-0.037490481304190915	[1085,1008]	[912,733]	-1	dCas9-KRAB	negative selection	5487146
53321275	53321298	X	+	27661255	K562	viability	GGAGACAGCGCTGGGGCCGGCGG	IQSEC2	ENSG00000124313	-0.7318093157766342	[1055,1131]	[578,479]	-8	dCas9-KRAB	negative selection	5487147
53281322	53281345	X	-	27661255	K562	viability	GTTCAAGTGGGAGATCCCATGGG	IQSEC2	ENSG00000124313	0.07708615307031152	[1126,1081]	[1047,831]	2	dCas9-KRAB	negative selection	5487148
53281504	53281527	X	-	27661255	K562	viability	GACCCATGGAGCCCCCCGGGAGG	IQSEC2	ENSG00000124313	-0.17320041556401872	[1079,1209]	[910,722]	-5	dCas9-KRAB	negative selection	5487149
53320934	53320957	X	-	27661255	K562	viability	GGAGAACCGCGACCTGCGAGAGG	IQSEC2	ENSG00000124313	-0.22835899517364355	[500,483]	[328,341]	-6	dCas9-KRAB	negative selection	5487150
53321069	53321092	X	-	27661255	K562	viability	GGGATCCGAGAGCCCAAATCGGG	IQSEC2	ENSG00000124313	0.2199778367227726	[471,556]	[581,387]	7	dCas9-KRAB	negative selection	5487151
53254701	53254724	X	+	27260156	BXPC3	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.04896436622537194	[451]	[530,469,392,561]	1	hSpCas9	negative selection	5549683
53241882	53241905	X	-	27260156	BXPC3	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.30269538494335557	[800]	[870,978,1125,1190]	6	hSpCas9	negative selection	5549684
53241875	53241898	X	+	27260156	BXPC3	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.08887735740223938	[527]	[418,569,519,578]	-2	hSpCas9	negative selection	5549685
53254709	53254732	X	-	27260156	BXPC3	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.09065796643458732	[467]	[425,432,441,549]	-2	hSpCas9	negative selection	5613939
53255823	53255846	X	+	27260156	BXPC3	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.15262553749361052	[702]	[749,776,774,990]	3	hSpCas9	negative selection	5613940
53256012	53256035	X	+	27260156	BXPC3	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.031394694752426955	[710]	[741,719,704,736]	0	hSpCas9	negative selection	5613941
53254701	53254724	X	+	27260156	A673	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	-0.1492372083863484	[451]	[483,512,476,480]	-4	hSpCas9	negative selection	5670934
53241882	53241905	X	-	27260156	A673	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.14928548691528865	[800]	[1198,1115,940,1020]	3	hSpCas9	negative selection	5670935
53241875	53241898	X	+	27260156	A673	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.4232917791097629	[527]	[411,441,456,578]	-8	hSpCas9	negative selection	5670936
53254709	53254732	X	-	27260156	A673	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.02371266802165202	[467]	[606,504,501,606]	0	hSpCas9	negative selection	5735190
53255823	53255846	X	+	27260156	A673	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.18699879507160083	[702]	[860,680,729,705]	-5	hSpCas9	negative selection	5735191
53256012	53256035	X	+	27260156	A673	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.043378600936400336	[710]	[1006,873,730,713]	-1	hSpCas9	negative selection	5735192
53254701	53254724	X	+	27260156	A375	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.14819640515803464	[451]	[631,665,424,621]	2	hSpCas9	negative selection	5792185
53241882	53241905	X	-	27260156	A375	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.6878328399245965	[800]	[1259,1878,1386,1541]	8	hSpCas9	negative selection	5792186
53241875	53241898	X	+	27260156	A375	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.18818963066078354	[527]	[510,765,393,524]	-3	hSpCas9	negative selection	5792187
53254709	53254732	X	-	27260156	A375	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.3040719794987053	[467]	[854,687,546,616]	4	hSpCas9	negative selection	5856441
53255823	53255846	X	+	27260156	A375	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.02628924058975668	[702]	[662,911,811,843]	0	hSpCas9	negative selection	5856442
53256012	53256035	X	+	27260156	A375	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.006464153928088079	[710]	[823,1055,712,777]	0	hSpCas9	negative selection	5856443
53254701	53254724	X	+	27260156	COLO741	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	-0.19487534581661367	[451]	[569,499,451]	-4	hSpCas9	negative selection	5913436
53241882	53241905	X	-	27260156	COLO741	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.3208158103241967	[800]	[1196,1358,1269]	6	hSpCas9	negative selection	5913437
53241875	53241898	X	+	27260156	COLO741	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.08808008006783079	[527]	[933,520,483]	-2	hSpCas9	negative selection	5913438
53254709	53254732	X	-	27260156	COLO741	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-6.1680773987800655e-06	[467]	[611,545,632]	0	hSpCas9	negative selection	5977692
53255823	53255846	X	+	27260156	COLO741	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.08727716736270108	[702]	[969,702,869]	-2	hSpCas9	negative selection	5977693
53256012	53256035	X	+	27260156	COLO741	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.19788119266514032	[710]	[979,717,698]	-4	hSpCas9	negative selection	5977694
53254701	53254724	X	+	27260156	CAL120	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.04350946277114415	[451]	[601,550,588]	0	hSpCas9	negative selection	6034687
53241882	53241905	X	-	27260156	CAL120	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.30000745255417094	[800]	[1582,1343,814]	4	hSpCas9	negative selection	6034688
53241875	53241898	X	+	27260156	CAL120	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.6436623754646451	[527]	[555,255,468]	-7	hSpCas9	negative selection	6034689
53254709	53254732	X	-	27260156	CAL120	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.25250753302365114	[467]	[688,680,709]	4	hSpCas9	negative selection	6098943
53255823	53255846	X	+	27260156	CAL120	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.09608896056758853	[702]	[1099,1096,637]	1	hSpCas9	negative selection	6098944
53256012	53256035	X	+	27260156	CAL120	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.23249760189358443	[710]	[1065,375,861]	-3	hSpCas9	negative selection	6098945
53254701	53254724	X	+	27260156	CADOES1	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.14837002756147702	[451]	[388,672,395,403]	2	hSpCas9	negative selection	6155938
53241882	53241905	X	-	27260156	CADOES1	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.42745062468952644	[800]	[984,914,1267,832]	7	hSpCas9	negative selection	6155939
53241875	53241898	X	+	27260156	CADOES1	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.4012757711268645	[527]	[224,362,467,433]	-6	hSpCas9	negative selection	6155940
53254709	53254732	X	-	27260156	CADOES1	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.21918841035403655	[467]	[414,494,480,640]	4	hSpCas9	negative selection	6220194
53255823	53255846	X	+	27260156	CADOES1	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.3905750787497616	[702]	[587,412,459,534]	-6	hSpCas9	negative selection	6220195
53256012	53256035	X	+	27260156	CADOES1	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.3501706806903478	[710]	[491,656,443,480]	-6	hSpCas9	negative selection	6220196
53254701	53254724	X	+	27260156	EWS502	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	-0.07572533909238588	[451]	[346,593,446,432]	-1	hSpCas9	negative selection	6277189
53241882	53241905	X	-	27260156	EWS502	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.14342369600127947	[800]	[1057,920,891,852]	2	hSpCas9	negative selection	6277190
53241875	53241898	X	+	27260156	EWS502	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.6125021448348331	[527]	[370,344,317,431]	-7	hSpCas9	negative selection	6277191
53254709	53254732	X	-	27260156	EWS502	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.12360764080812271	[467]	[523,406,657,580]	2	hSpCas9	negative selection	6341445
53255823	53255846	X	+	27260156	EWS502	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.25748749679300187	[702]	[779,391,610,701]	-4	hSpCas9	negative selection	6341446
53256012	53256035	X	+	27260156	EWS502	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.05633865272757399	[710]	[714,566,673,961]	-1	hSpCas9	negative selection	6341447
53254701	53254724	X	+	27260156	EW8	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	-0.3057156465443142	[451]	[272,297,283,328]	-5	hSpCas9	negative selection	6398440
53241882	53241905	X	-	27260156	EW8	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.42588241884727207	[800]	[904,863,909,803]	7	hSpCas9	negative selection	6398441
53241875	53241898	X	+	27260156	EW8	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.5007771049086907	[527]	[232,369,220,390]	-7	hSpCas9	negative selection	6398442
53254709	53254732	X	-	27260156	EW8	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.18538909947171853	[467]	[513,271,243,337]	-4	hSpCas9	negative selection	6462696
53255823	53255846	X	+	27260156	EW8	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.028800873457286214	[702]	[1005,344,540,391]	0	hSpCas9	negative selection	6462697
53256012	53256035	X	+	27260156	EW8	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.12120937308422486	[710]	[524,598,388,627]	-2	hSpCas9	negative selection	6462698
53254701	53254724	X	+	27260156	CORL105	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.2187742493985894	[451]	[904,508,604,454]	4	hSpCas9	negative selection	6519691
53241882	53241905	X	-	27260156	CORL105	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.07167640160243982	[800]	[1115,896,1216,754]	1	hSpCas9	negative selection	6519692
53241875	53241898	X	+	27260156	CORL105	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.4256757271062297	[527]	[489,408,531,422]	-7	hSpCas9	negative selection	6519693
53254709	53254732	X	-	27260156	CORL105	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.1343135240801737	[467]	[440,540,876,584]	2	hSpCas9	negative selection	6583947
53255823	53255846	X	+	27260156	CORL105	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.28685162675698556	[702]	[562,841,747,549]	-5	hSpCas9	negative selection	6583948
53256012	53256035	X	+	27260156	CORL105	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.12130181833036324	[710]	[721,1074,1064,774]	2	hSpCas9	negative selection	6583949
53254701	53254724	X	+	27260156	HS294T	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.18702551338186058	[451]	[267,162,147,212]	2	hSpCas9	negative selection	6640942
53241882	53241905	X	-	27260156	HS294T	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.6279209129455765	[800]	[352,394,575,628]	7	hSpCas9	negative selection	6640943
53241875	53241898	X	+	27260156	HS294T	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.05146974694186486	[527]	[182,216,150,244]	0	hSpCas9	negative selection	6640944
53254709	53254732	X	-	27260156	HS294T	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.45491156214427275	[467]	[228,314,197,248]	6	hSpCas9	negative selection	6705198
53255823	53255846	X	+	27260156	HS294T	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.09164630128583523	[702]	[185,294,202,357]	-1	hSpCas9	negative selection	6705199
53256012	53256035	X	+	27260156	HS294T	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.3547838952370742	[710]	[320,348,416,314]	5	hSpCas9	negative selection	6705200
53254701	53254724	X	+	27260156	HCC44	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.07828432648488286	[451]	[497,634,346,620]	1	hSpCas9	negative selection	6762193
53241882	53241905	X	-	27260156	HCC44	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.4221291491561343	[800]	[1348,1173,1307,1053]	7	hSpCas9	negative selection	6762194
53241875	53241898	X	+	27260156	HCC44	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.6536675994195542	[527]	[397,332,331,449]	-7	hSpCas9	negative selection	6762195
53254709	53254732	X	-	27260156	HCC44	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.3569162988601659	[467]	[866,640,738,497]	6	hSpCas9	negative selection	6826449
53255823	53255846	X	+	27260156	HCC44	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.2545892210568179	[702]	[703,648,671,642]	-4	hSpCas9	negative selection	6826450
53256012	53256035	X	+	27260156	HCC44	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.2897187755439312	[710]	[622,625,736,654]	-4	hSpCas9	negative selection	6826451
53254701	53254724	X	+	27260156	G402	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.502262425680872	[451]	[394,644,1700,338]	6	hSpCas9	negative selection	6883444
53241882	53241905	X	-	27260156	G402	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.42375775792356474	[800]	[1822,1471,1129,916]	5	hSpCas9	negative selection	6883445
53241875	53241898	X	+	27260156	G402	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.41993852158090894	[527]	[356,270,1056,221]	-5	hSpCas9	negative selection	6883446
53254709	53254732	X	-	27260156	G402	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.6223342349215076	[467]	[864,938,782,924]	7	hSpCas9	negative selection	6947700
53255823	53255846	X	+	27260156	G402	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.7022671606747625	[702]	[534,611,441,523]	-7	hSpCas9	negative selection	6947701
53256012	53256035	X	+	27260156	G402	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.06680575302374048	[710]	[1037,1046,750,825]	0	hSpCas9	negative selection	6947702
53254701	53254724	X	+	27260156	L33	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.25141293017654615	[451]	[603,141,337,660]	5	hSpCas9	negative selection	7004695
53241882	53241905	X	-	27260156	L33	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.24762292522927787	[800]	[1073,352,629,863]	5	hSpCas9	negative selection	7004696
53241875	53241898	X	+	27260156	L33	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.08180952867417328	[527]	[373,266,286,515]	-2	hSpCas9	negative selection	7004697
53254709	53254732	X	-	27260156	L33	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.08736063806526977	[467]	[458,188,311,345]	-2	hSpCas9	negative selection	7068951
53255823	53255846	X	+	27260156	L33	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.10550083346534356	[702]	[761,318,439,783]	2	hSpCas9	negative selection	7068952
53256012	53256035	X	+	27260156	L33	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.32029930285933	[710]	[578,267,309,550]	-6	hSpCas9	negative selection	7068953
53254701	53254724	X	+	27260156	K562	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.2612770086358602	[451]	[334,447,451,651]	3	hSpCas9	negative selection	7125946
53241882	53241905	X	-	27260156	K562	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.4347927606083273	[800]	[1251,599,897,1079]	5	hSpCas9	negative selection	7125947
53241875	53241898	X	+	27260156	K562	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.4066171285541839	[527]	[425,197,647,160]	-5	hSpCas9	negative selection	7125948
53254709	53254732	X	-	27260156	K562	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.23971368089985198	[467]	[666,429,498,386]	3	hSpCas9	negative selection	7190202
53255823	53255846	X	+	27260156	K562	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.1021615814082365	[702]	[665,478,582,908]	1	hSpCas9	negative selection	7190203
53256012	53256035	X	+	27260156	K562	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.408541174001281	[710]	[839,964,886,679]	5	hSpCas9	negative selection	7190204
53254701	53254724	X	+	27260156	HT29	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.09445529430447808	[451]	[556,749,603,458]	1	hSpCas9	negative selection	7247197
53241882	53241905	X	-	27260156	HT29	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.40122516606172587	[800]	[1362,1441,1326,1050]	7	hSpCas9	negative selection	7247198
53241875	53241898	X	+	27260156	HT29	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.38211890453492303	[527]	[476,527,387,565]	-6	hSpCas9	negative selection	7247199
53254709	53254732	X	-	27260156	HT29	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.048840058772908555	[467]	[493,804,530,401]	-1	hSpCas9	negative selection	7311453
53255823	53255846	X	+	27260156	HT29	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.056220306893251526	[702]	[905,898,973,783]	1	hSpCas9	negative selection	7311454
53256012	53256035	X	+	27260156	HT29	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.15473348032211554	[710]	[819,767,795,724]	-3	hSpCas9	negative selection	7311455
53254701	53254724	X	+	27260156	MHHES1	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.2580734875843462	[451]	[741,490,613,583]	5	hSpCas9	negative selection	7368448
53241882	53241905	X	-	27260156	MHHES1	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.1907330219985739	[800]	[1151,1063,1251,719]	3	hSpCas9	negative selection	7368449
53241875	53241898	X	+	27260156	MHHES1	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.14230810537710173	[527]	[268,493,960,413]	-3	hSpCas9	negative selection	7368450
53254709	53254732	X	-	27260156	MHHES1	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.17574298741652122	[467]	[661,557,699,479]	3	hSpCas9	negative selection	7432704
53255823	53255846	X	+	27260156	MHHES1	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.13440236475715606	[702]	[1043,844,598,486]	-3	hSpCas9	negative selection	7432705
53256012	53256035	X	+	27260156	MHHES1	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.24098515349541028	[710]	[725,771,659,575]	-4	hSpCas9	negative selection	7432706
53254701	53254724	X	+	27260156	MEWO	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.04766438461815707	[451]	[539,452,337]	1	hSpCas9	negative selection	7489699
53241882	53241905	X	-	27260156	MEWO	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.4139363208901594	[800]	[1371,876,818]	8	hSpCas9	negative selection	7489700
53241875	53241898	X	+	27260156	MEWO	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.26322639062991754	[527]	[458,384,399]	-5	hSpCas9	negative selection	7489701
53254709	53254732	X	-	27260156	MEWO	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.287258358138537	[467]	[382,356,340]	-6	hSpCas9	negative selection	7553955
53255823	53255846	X	+	27260156	MEWO	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.1616094018318986	[702]	[531,592,627]	-4	hSpCas9	negative selection	7553956
53256012	53256035	X	+	27260156	MEWO	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.0982752412013389	[710]	[597,513,747]	-2	hSpCas9	negative selection	7553957
53254701	53254724	X	+	27260156	LNCAPCLONEFGC	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.24653615180358168	[451]	[450,428,720,380]	4	hSpCas9	negative selection	7610950
53241882	53241905	X	-	27260156	LNCAPCLONEFGC	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.48511544015596986	[800]	[1050,730,1157,1160]	7	hSpCas9	negative selection	7610951
53241875	53241898	X	+	27260156	LNCAPCLONEFGC	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.22616229991962772	[527]	[422,289,503,439]	-4	hSpCas9	negative selection	7610952
53254709	53254732	X	-	27260156	LNCAPCLONEFGC	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.31033280201072383	[467]	[667,315,508,617]	5	hSpCas9	negative selection	7675206
53255823	53255846	X	+	27260156	LNCAPCLONEFGC	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.1617424741741625	[702]	[434,803,610,419]	-3	hSpCas9	negative selection	7675207
53256012	53256035	X	+	27260156	LNCAPCLONEFGC	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.07271077297963957	[710]	[652,500,660,647]	-1	hSpCas9	negative selection	7675208
53254701	53254724	X	+	27260156	PANC0327	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.5750025404831719	[451]	[543,641,498,696]	8	hSpCas9	negative selection	7732201
53241882	53241905	X	-	27260156	PANC0327	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.17688046755537334	[800]	[994,719,925,602]	2	hSpCas9	negative selection	7732202
53241875	53241898	X	+	27260156	PANC0327	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	0.43582270804024836	[527]	[624,341,1337,270]	6	hSpCas9	negative selection	7732203
53254709	53254732	X	-	27260156	PANC0327	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.019585975190206453	[467]	[543,508,251,378]	0	hSpCas9	negative selection	7796457
53255823	53255846	X	+	27260156	PANC0327	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.0687401806228134	[702]	[592,362,664,1030]	1	hSpCas9	negative selection	7796458
53256012	53256035	X	+	27260156	PANC0327	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.18695524795113427	[710]	[601,773,740,741]	2	hSpCas9	negative selection	7796459
53254701	53254724	X	+	27260156	NCIH2009	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	-0.11568684961187439	[451]	[726,530,518]	-2	hSpCas9	negative selection	7853452
53241882	53241905	X	-	27260156	NCIH2009	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.5544969315296622	[800]	[2070,1340,1605]	7	hSpCas9	negative selection	7853453
53241875	53241898	X	+	27260156	NCIH2009	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	0.2775884233540046	[527]	[1098,706,918]	4	hSpCas9	negative selection	7853454
53254709	53254732	X	-	27260156	NCIH2009	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.32577506925538874	[467]	[1074,800,631]	4	hSpCas9	negative selection	7917708
53255823	53255846	X	+	27260156	NCIH2009	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.006672176171803601	[702]	[902,954,1058]	0	hSpCas9	negative selection	7917709
53256012	53256035	X	+	27260156	NCIH2009	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.06650281408795444	[710]	[1145,853,884]	-1	hSpCas9	negative selection	7917710
53254701	53254724	X	+	27260156	NCIH1373	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.6007769711174767	[451]	[1130,878,469,165]	6	hSpCas9	negative selection	7974703
53241882	53241905	X	-	27260156	NCIH1373	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.7915198358826301	[800]	[1781,1120,1772,423]	7	hSpCas9	negative selection	7974704
53241875	53241898	X	+	27260156	NCIH1373	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.413494091176326	[527]	[450,414,589,81]	-4	hSpCas9	negative selection	7974705
53254709	53254732	X	-	27260156	NCIH1373	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.7831042492313991	[467]	[1080,1110,811,154]	7	hSpCas9	negative selection	8038959
53255823	53255846	X	+	27260156	NCIH1373	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.23735339296830948	[702]	[1340,935,771,187]	2	hSpCas9	negative selection	8038960
53256012	53256035	X	+	27260156	NCIH1373	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.3329504095536687	[710]	[1440,977,730,244]	3	hSpCas9	negative selection	8038961
53254701	53254724	X	+	27260156	PATU8902	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.30075918192052514	[451]	[694,993,804,570]	3	hSpCas9	negative selection	8095954
53241882	53241905	X	-	27260156	PATU8902	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.8668262240943034	[800]	[2404,2479,1363,2043]	8	hSpCas9	negative selection	8095955
53241875	53241898	X	+	27260156	PATU8902	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	0.12353882668786673	[527]	[773,902,776,743]	1	hSpCas9	negative selection	8095956
53254709	53254732	X	-	27260156	PATU8902	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.34182994739228395	[467]	[604,879,667,1237]	3	hSpCas9	negative selection	8160210
53255823	53255846	X	+	27260156	PATU8902	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.6577288924702097	[702]	[1741,1036,1132,2466]	7	hSpCas9	negative selection	8160211
53256012	53256035	X	+	27260156	PATU8902	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.3489100833271125	[710]	[1407,1122,822,1863]	3	hSpCas9	negative selection	8160212
53254701	53254724	X	+	27260156	PANC1	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	-0.1529278718785644	[451]	[291,446,323,348]	-2	hSpCas9	negative selection	8217205
53241882	53241905	X	-	27260156	PANC1	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.3938841310887078	[800]	[827,1159,862,817]	6	hSpCas9	negative selection	8217206
53241875	53241898	X	+	27260156	PANC1	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.23558466547169216	[527]	[404,428,512,223]	-4	hSpCas9	negative selection	8217207
53254709	53254732	X	-	27260156	PANC1	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.026853624119913426	[467]	[386,469,470,329]	0	hSpCas9	negative selection	8281461
53255823	53255846	X	+	27260156	PANC1	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.07900346155652249	[702]	[868,834,458,443]	1	hSpCas9	negative selection	8281462
53256012	53256035	X	+	27260156	PANC1	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.01779942122587541	[710]	[526,839,831,356]	0	hSpCas9	negative selection	8281463
53254701	53254724	X	+	27260156	PANC0813	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.2859883329252442	[451]	[615,491,772,701]	4	hSpCas9	negative selection	8338456
53241882	53241905	X	-	27260156	PANC0813	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.48496033793460525	[800]	[1438,1044,1453,1337]	7	hSpCas9	negative selection	8338457
53241875	53241898	X	+	27260156	PANC0813	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	0.09624622535951269	[527]	[861,680,662,473]	1	hSpCas9	negative selection	8338458
53254709	53254732	X	-	27260156	PANC0813	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.13507419676407775	[467]	[630,654,579,552]	2	hSpCas9	negative selection	8402712
53255823	53255846	X	+	27260156	PANC0813	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.03603781066832623	[702]	[925,782,750,772]	0	hSpCas9	negative selection	8402713
53256012	53256035	X	+	27260156	PANC0813	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.08284168165408612	[710]	[1212,781,623,583]	-1	hSpCas9	negative selection	8402714
53254701	53254724	X	+	27260156	RDES	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.11169745458567497	[451]	[552,472,687,522]	1	hSpCas9	negative selection	8459707
53241882	53241905	X	-	27260156	RDES	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.3752509798416841	[800]	[1016,946,1533,1342]	6	hSpCas9	negative selection	8459708
53241875	53241898	X	+	27260156	RDES	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.6690632395775342	[527]	[302,346,431,469]	-8	hSpCas9	negative selection	8459709
53254709	53254732	X	-	27260156	RDES	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.15187156148257172	[467]	[513,476,675,764]	2	hSpCas9	negative selection	8523963
53255823	53255846	X	+	27260156	RDES	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.01394182857063686	[702]	[548,675,990,1157]	0	hSpCas9	negative selection	8523964
53256012	53256035	X	+	27260156	RDES	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.17648375290308516	[710]	[642,709,792,749]	-3	hSpCas9	negative selection	8523965
53254701	53254724	X	+	27260156	PC3	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.11374680356937174	[451]	[259,497,985,456]	2	hSpCas9	negative selection	8580958
53241882	53241905	X	-	27260156	PC3	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.27279971650961854	[800]	[553,852,1781,1093]	6	hSpCas9	negative selection	8580959
53241875	53241898	X	+	27260156	PC3	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.43609733929267747	[527]	[271,339,910,242]	-7	hSpCas9	negative selection	8580960
53254709	53254732	X	-	27260156	PC3	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.003207623858378576	[467]	[288,396,801,553]	0	hSpCas9	negative selection	8645214
53255823	53255846	X	+	27260156	PC3	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.15716055114444533	[702]	[537,594,727,651]	-4	hSpCas9	negative selection	8645215
53256012	53256035	X	+	27260156	PC3	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.1759069203459649	[710]	[494,442,1060,675]	-4	hSpCas9	negative selection	8645216
53254701	53254724	X	+	27260156	PATU8988T	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.016401290203325848	[451]	[345,434,433,560]	0	hSpCas9	negative selection	8702209
53241882	53241905	X	-	27260156	PATU8988T	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.2824192879974934	[800]	[883,825,751,1325]	5	hSpCas9	negative selection	8702210
53241875	53241898	X	+	27260156	PATU8988T	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.16556910497318017	[527]	[553,344,417,495]	-3	hSpCas9	negative selection	8702211
53254709	53254732	X	-	27260156	PATU8988T	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.08182057631472495	[467]	[290,436,359,639]	-1	hSpCas9	negative selection	8766465
53255823	53255846	X	+	27260156	PATU8988T	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.45616344470152925	[702]	[466,570,378,578]	-6	hSpCas9	negative selection	8766466
53256012	53256035	X	+	27260156	PATU8988T	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.04621889024701242	[710]	[720,792,375,797]	-1	hSpCas9	negative selection	8766467
53254701	53254724	X	+	27260156	T47D	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.14403719688105698	[451]	[605,586,579,552]	3	hSpCas9	negative selection	8823460
53241882	53241905	X	-	27260156	T47D	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.439250883316052	[800]	[1220,1127,1239,1490]	8	hSpCas9	negative selection	8823461
53241875	53241898	X	+	27260156	T47D	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.3343398848674525	[527]	[432,485,530,500]	-6	hSpCas9	negative selection	8823462
53254709	53254732	X	-	27260156	T47D	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.038088200633039124	[467]	[543,518,548,632]	0	hSpCas9	negative selection	8887716
53255823	53255846	X	+	27260156	T47D	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.07518505599734515	[702]	[848,742,827,688]	-2	hSpCas9	negative selection	8887717
53256012	53256035	X	+	27260156	T47D	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.05894895061308747	[710]	[701,717,864,903]	-1	hSpCas9	negative selection	8887718
53254701	53254724	X	+	27260156	SU8686	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.3178835259812238	[451]	[625,356,524,774]	5	hSpCas9	negative selection	8944711
53241882	53241905	X	-	27260156	SU8686	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.29933797927764116	[800]	[890,1056,888,1077]	5	hSpCas9	negative selection	8944712
53241875	53241898	X	+	27260156	SU8686	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.16919004614552519	[527]	[387,308,567,656]	-3	hSpCas9	negative selection	8944713
53254709	53254732	X	-	27260156	SU8686	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.2092571555465409	[467]	[312,462,378,457]	-4	hSpCas9	negative selection	9008967
53255823	53255846	X	+	27260156	SU8686	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.2455507440481744	[702]	[540,560,638,621]	-4	hSpCas9	negative selection	9008968
53256012	53256035	X	+	27260156	SU8686	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.15589925623748346	[710]	[529,605,846,550]	-3	hSpCas9	negative selection	9008969
53254701	53254724	X	+	27260156	SKES1	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.06850597196758859	[451]	[509,443,439,491]	1	hSpCas9	negative selection	9065962
53241882	53241905	X	-	27260156	SKES1	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.4285549127319934	[800]	[1735,804,1030,809]	8	hSpCas9	negative selection	9065963
53241875	53241898	X	+	27260156	SKES1	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.5538588589253214	[527]	[552,386,349,191]	-8	hSpCas9	negative selection	9065964
53254709	53254732	X	-	27260156	SKES1	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	0.2134089357577441	[467]	[736,524,407,518]	4	hSpCas9	negative selection	9130218
53255823	53255846	X	+	27260156	SKES1	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.19517482897036614	[702]	[694,693,487,591]	-4	hSpCas9	negative selection	9130219
53256012	53256035	X	+	27260156	SKES1	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.2750019511330936	[710]	[500,703,630,512]	-6	hSpCas9	negative selection	9130220
53254701	53254724	X	+	27260156	TOV112D	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.01136731468441228	[451]	[475,737,356,327]	0	hSpCas9	negative selection	9187213
53241882	53241905	X	-	27260156	TOV112D	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.2557454015909266	[800]	[770,1131,999,953]	5	hSpCas9	negative selection	9187214
53241875	53241898	X	+	27260156	TOV112D	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.29824040117085726	[527]	[589,334,477,309]	-5	hSpCas9	negative selection	9187215
53254709	53254732	X	-	27260156	TOV112D	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.20940865440273335	[467]	[510,416,383,322]	-4	hSpCas9	negative selection	9251469
53255823	53255846	X	+	27260156	TOV112D	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	-0.41564746861071206	[702]	[514,533,753,313]	-7	hSpCas9	negative selection	9251470
53256012	53256035	X	+	27260156	TOV112D	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	-0.4108954462538683	[710]	[563,678,536,402]	-7	hSpCas9	negative selection	9251471
53254701	53254724	X	+	27260156	TC71	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.06995413576424019	[451]	[440,576,546,466]	1	hSpCas9	negative selection	9308464
53241882	53241905	X	-	27260156	TC71	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.17021625710657373	[800]	[928,1108,900,925]	4	hSpCas9	negative selection	9308465
53241875	53241898	X	+	27260156	TC71	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.23643410534117876	[527]	[545,450,457,464]	-6	hSpCas9	negative selection	9308466
53254709	53254732	X	-	27260156	TC71	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.16004429822267094	[467]	[516,368,429,480]	-4	hSpCas9	negative selection	9372720
53255823	53255846	X	+	27260156	TC71	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.166084398932971	[702]	[1007,799,670,908]	4	hSpCas9	negative selection	9372721
53256012	53256035	X	+	27260156	TC71	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.0691649155535784	[710]	[789,650,956,794]	1	hSpCas9	negative selection	9372722
53254701	53254724	X	+	27260156	TC32	viability	AGGCTTGCCCTCGAAGTACGCGG	IQSEC2	ENSG00000124313	0.14591209656339263	[451]	[453,325,525,620]	2	hSpCas9	negative selection	9429715
53241882	53241905	X	-	27260156	TC32	viability	GTCTCTCCCTCACCGTCGACTGG	IQSEC2	ENSG00000124313	0.2624469908385023	[800]	[906,773,1107,845]	5	hSpCas9	negative selection	9429716
53241875	53241898	X	+	27260156	TC32	viability	CAGCAAACCAGTCGACGGTGAGG	IQSEC2	ENSG00000124313	-0.5195071299338188	[527]	[291,342,387,354]	-7	hSpCas9	negative selection	9429717
53254709	53254732	X	-	27260156	TC32	viability	ACAGAACCCCGCGTACTTCGAGG	IQSEC2	ENSG00000124313	-0.0006086315523990866	[467]	[382,432,557,382]	0	hSpCas9	negative selection	9493971
53255823	53255846	X	+	27260156	TC32	viability	AGAGTTCATAGCTGTCCGATAGG	IQSEC2	ENSG00000124313	0.05676524943028827	[702]	[648,588,770,756]	1	hSpCas9	negative selection	9493972
53256012	53256035	X	+	27260156	TC32	viability	GACTATCAACCGCTGTGCTCAGG	IQSEC2	ENSG00000124313	0.1776970578822501	[710]	[849,534,930,762]	3	hSpCas9	negative selection	9493973
53248154	53248177	X	+	27869803	HPAFII	viability after 27 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.40789726039219876	[381]	[386,165,NaN]	3	hSpCas9	negative selection	9609132
53248780	53248803	X	-	27869803	HPAFII	viability after 27 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	-0.42422893017122054	[254]	[160,48,NaN]	-3	hSpCas9	negative selection	9609133
53250669	53250692	X	-	27869803	HPAFII	viability after 27 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.0900073580063882	[340]	[168,208,NaN]	0	hSpCas9	negative selection	9609134
53254685	53254708	X	-	27869803	HPAFII	viability after 27 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.05165333225170121	[164]	[90,88,NaN]	0	hSpCas9	negative selection	9609135
53255928	53255951	X	+	27869803	HPAFII	viability after 27 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.15520952407829852	[174]	[132,76,NaN]	1	hSpCas9	negative selection	9609136
53320855	53320878	X	+	27869803	HPAFII	viability after 27 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.3363432028275989	[198]	[250,32,NaN]	2	hSpCas9	negative selection	9609137
53248154	53248177	X	+	27869803	HPAFII	viability after 15 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.16388190186073937	[381]	[647,342,NaN]	2	hSpCas9	negative selection	9691581
53248780	53248803	X	-	27869803	HPAFII	viability after 15 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	-0.18329295539731325	[254]	[331,184,NaN]	-2	hSpCas9	negative selection	9691582
53250669	53250692	X	-	27869803	HPAFII	viability after 15 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.2824859156950072	[340]	[610,342,NaN]	3	hSpCas9	negative selection	9691583
53254685	53254708	X	-	27869803	HPAFII	viability after 15 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.11487839801649719	[164]	[138,224,NaN]	1	hSpCas9	negative selection	9691584
53255928	53255951	X	+	27869803	HPAFII	viability after 15 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	-0.09086695638433673	[174]	[146,194,NaN]	-1	hSpCas9	negative selection	9691585
53320855	53320878	X	+	27869803	HPAFII	viability after 15 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.26090378396069847	[198]	[431,146,NaN]	3	hSpCas9	negative selection	9691586
53248154	53248177	X	+	27869803	ASPC1	viability after 36 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.564249780903366	[756]	[736,412,125]	5	hSpCas9	negative selection	9774030
53248780	53248803	X	-	27869803	ASPC1	viability after 36 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	0.4996286981609248	[355]	[71,246,189]	5	hSpCas9	negative selection	9774031
53250669	53250692	X	-	27869803	ASPC1	viability after 36 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.03072333996605303	[976]	[339,231,442]	0	hSpCas9	negative selection	9774032
53254685	53254708	X	-	27869803	ASPC1	viability after 36 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	-0.6133834432381692	[350]	[205,16,40]	-6	hSpCas9	negative selection	9774033
53255928	53255951	X	+	27869803	ASPC1	viability after 36 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.4407856464866816	[384]	[363,174,58]	4	hSpCas9	negative selection	9774034
53320855	53320878	X	+	27869803	ASPC1	viability after 36 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	-0.41577324872252663	[533]	[139,96,171]	-4	hSpCas9	negative selection	9774035
53248154	53248177	X	+	27869803	PATU8988S	viability after 35 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	-0.38020878932299784	[751]	[320,143,NaN]	-4	hSpCas9	negative selection	9856479
53248780	53248803	X	-	27869803	PATU8988S	viability after 35 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	-1.3592432512767834	[518]	[70,91,NaN]	-8	hSpCas9	negative selection	9856480
53250669	53250692	X	-	27869803	PATU8988S	viability after 35 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	-0.2936728024827314	[833]	[286,260,NaN]	-3	hSpCas9	negative selection	9856481
53254685	53254708	X	-	27869803	PATU8988S	viability after 35 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	-0.49040646698168266	[318]	[70,111,NaN]	-5	hSpCas9	negative selection	9856482
53255928	53255951	X	+	27869803	PATU8988S	viability after 35 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	-0.07914852543378831	[395]	[139,161,NaN]	-1	hSpCas9	negative selection	9856483
53320855	53320878	X	+	27869803	PATU8988S	viability after 35 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	1.047880300603049	[421]	[303,398,NaN]	9	hSpCas9	negative selection	9856484
53248154	53248177	X	+	27869803	PATU8988S	viability after 31 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	-0.045823031331878095	[751]	[293,285,NaN]	0	hSpCas9	negative selection	9938928
53248780	53248803	X	-	27869803	PATU8988S	viability after 31 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	-1.577174557592076	[518]	[49,93,NaN]	-8	hSpCas9	negative selection	9938929
53250669	53250692	X	-	27869803	PATU8988S	viability after 31 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	-1.0035207061940226	[833]	[120,222,NaN]	-7	hSpCas9	negative selection	9938930
53254685	53254708	X	-	27869803	PATU8988S	viability after 31 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	-0.4382371205983361	[318]	[81,108,NaN]	-5	hSpCas9	negative selection	9938931
53255928	53255951	X	+	27869803	PATU8988S	viability after 31 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.11423592140173972	[395]	[140,208,NaN]	1	hSpCas9	negative selection	9938932
53320855	53320878	X	+	27869803	PATU8988S	viability after 31 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	1.201329502413232	[421]	[283,517,NaN]	9	hSpCas9	negative selection	9938933
53248154	53248177	X	+	27869803	HPAFII	viability after 35 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.27546302033153247	[381]	[258,205,NaN]	1	hSpCas9	negative selection	10021377
53248780	53248803	X	-	27869803	HPAFII	viability after 35 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	0.033079314582887494	[254]	[188,67,NaN]	0	hSpCas9	negative selection	10021378
53250669	53250692	X	-	27869803	HPAFII	viability after 35 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.3921928690692636	[340]	[163,296,NaN]	2	hSpCas9	negative selection	10021379
53254685	53254708	X	-	27869803	HPAFII	viability after 35 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	0.8162143052509631	[164]	[68,234,NaN]	5	hSpCas9	negative selection	10021380
53255928	53255951	X	+	27869803	HPAFII	viability after 35 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.8266962759719331	[174]	[182,127,NaN]	5	hSpCas9	negative selection	10021381
53320855	53320878	X	+	27869803	HPAFII	viability after 35 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	1.1103486319845965	[198]	[399,11,NaN]	7	hSpCas9	negative selection	10021382
53248154	53248177	X	+	27869803	HPAFII	viability after 31 days	CCTGAACCCGGATATGGGACTGG	IQSEC2	ENSG00000124313	0.09981856928427713	[381]	[290,162,NaN]	0	hSpCas9	negative selection	10103826
53248780	53248803	X	-	27869803	HPAFII	viability after 31 days	TGGAGCGGAAAGGCCTCAGCCGG	IQSEC2	ENSG00000124313	-0.11994894968109199	[254]	[135,126,NaN]	-1	hSpCas9	negative selection	10103827
53250669	53250692	X	-	27869803	HPAFII	viability after 31 days	CATGGGACCCTGAAGCACAAGGG	IQSEC2	ENSG00000124313	0.549835736264338	[340]	[171,397,NaN]	4	hSpCas9	negative selection	10103828
53254685	53254708	X	-	27869803	HPAFII	viability after 31 days	CAAGCCTGCCTCGCTGGACGAGG	IQSEC2	ENSG00000124313	-0.07680197992256232	[164]	[60,116,NaN]	0	hSpCas9	negative selection	10103829
53255928	53255951	X	+	27869803	HPAFII	viability after 31 days	GAAGGCCCACTCCAGCAGGGGGG	IQSEC2	ENSG00000124313	0.42076558407861114	[174]	[141,119,NaN]	3	hSpCas9	negative selection	10103830
53320855	53320878	X	+	27869803	HPAFII	viability after 31 days	TGGTACTGGCTCTCGCGGCCCGG	IQSEC2	ENSG00000124313	0.705786336935329	[198]	[341,7,NaN]	5	hSpCas9	negative selection	10103831
53250368	53250391	X	-	28162770	P31FUJ	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	0.7368241465421027	[167]	[328]	8	hSpCas9	negative selection	10175572
53250780	53250803	X	+	28162770	P31FUJ	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-0.16319673692851197	[262]	[275]	-1	hSpCas9	negative selection	10175573
53255976	53255999	X	+	28162770	P31FUJ	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	-0.21457844579547125	[235]	[238]	-2	hSpCas9	negative selection	10175574
53255926	53255949	X	+	28162770	P31FUJ	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	-0.29313273861570033	[292]	[280]	-3	hSpCas9	negative selection	10175575
53255910	53255933	X	+	28162770	P31FUJ	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.35700969596817345	[395]	[595]	4	hSpCas9	negative selection	10175576
53254769	53254792	X	+	28162770	P31FUJ	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.760938805113939	[461]	[919]	8	hSpCas9	negative selection	10175577
53251111	53251134	X	+	28162770	P31FUJ	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	0.7330899412653571	[106]	[208]	8	hSpCas9	negative selection	10175578
53251057	53251080	X	-	28162770	P31FUJ	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	0.09299741485354374	[520]	[652]	0	hSpCas9	negative selection	10175579
53250900	53250923	X	+	28162770	P31FUJ	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-0.6478397036932222	[7]	[5]	-5	hSpCas9	negative selection	10175580
53250852	53250875	X	-	28162770	P31FUJ	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.4331668594525677	[403]	[640]	5	hSpCas9	negative selection	10175581
53250368	53250391	X	-	28162770	TF1	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	NaN	[NaN]	[354]	1	hSpCas9	negative selection	10344938
53250780	53250803	X	+	28162770	TF1	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10344939
53255976	53255999	X	+	28162770	TF1	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	NaN	[NaN]	[258]	1	hSpCas9	negative selection	10344940
53255926	53255949	X	+	28162770	TF1	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	NaN	[NaN]	[263]	1	hSpCas9	negative selection	10344941
53255910	53255933	X	+	28162770	TF1	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	NaN	[NaN]	[555]	1	hSpCas9	negative selection	10344942
53254769	53254792	X	+	28162770	TF1	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	NaN	[NaN]	[420]	1	hSpCas9	negative selection	10344943
53251111	53251134	X	+	28162770	TF1	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	NaN	[NaN]	[215]	1	hSpCas9	negative selection	10344944
53251057	53251080	X	-	28162770	TF1	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	NaN	[NaN]	[317]	1	hSpCas9	negative selection	10344945
53250900	53250923	X	+	28162770	TF1	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10344946
53250852	53250875	X	-	28162770	TF1	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	NaN	[NaN]	[586]	1	hSpCas9	negative selection	10344947
53250368	53250391	X	-	28162770	SKM1	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	0.9724141683281003	[31]	[110]	8	hSpCas9	negative selection	10514304
53250780	53250803	X	+	28162770	SKM1	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-1.164889411545014	[51]	[40]	-7	hSpCas9	negative selection	10514305
53255976	53255999	X	+	28162770	SKM1	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	0.299988826356605	[67]	[147]	3	hSpCas9	negative selection	10514306
53255926	53255949	X	+	28162770	SKM1	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	-0.7868122695597055	[80]	[82]	-5	hSpCas9	negative selection	10514307
53255910	53255933	X	+	28162770	SKM1	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.07846262842708018	[104]	[195]	0	hSpCas9	negative selection	10514308
53254769	53254792	X	+	28162770	SKM1	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.2469456556954861	[142]	[299]	2	hSpCas9	negative selection	10514309
53251111	53251134	X	+	28162770	SKM1	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	0.7040671136455822	[24]	[71]	6	hSpCas9	negative selection	10514310
53251057	53251080	X	-	28162770	SKM1	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	-0.3649566722215861	[109]	[150]	-3	hSpCas9	negative selection	10514311
53250900	53250923	X	+	28162770	SKM1	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-1.8220016980220048	[1]	[0]	-8	hSpCas9	negative selection	10514312
53250852	53250875	X	-	28162770	SKM1	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.001120539893915251	[90]	[160]	0	hSpCas9	negative selection	10514313
53250368	53250391	X	-	28162770	SKM1	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	0.9724141683281003	[31]	[110]	8	hSpCas9	negative selection	10683670
53250780	53250803	X	+	28162770	SKM1	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-1.164889411545014	[51]	[40]	-7	hSpCas9	negative selection	10683671
53255976	53255999	X	+	28162770	SKM1	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	0.299988826356605	[67]	[147]	3	hSpCas9	negative selection	10683672
53255926	53255949	X	+	28162770	SKM1	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	-0.7868122695597055	[80]	[82]	-5	hSpCas9	negative selection	10683673
53255910	53255933	X	+	28162770	SKM1	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.07846262842708018	[104]	[195]	0	hSpCas9	negative selection	10683674
53254769	53254792	X	+	28162770	SKM1	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.2469456556954861	[142]	[299]	2	hSpCas9	negative selection	10683675
53251111	53251134	X	+	28162770	SKM1	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	0.7040671136455822	[24]	[71]	6	hSpCas9	negative selection	10683676
53251057	53251080	X	-	28162770	SKM1	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	-0.3649566722215861	[109]	[150]	-3	hSpCas9	negative selection	10683677
53250900	53250923	X	+	28162770	SKM1	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-1.8220016980220048	[1]	[0]	-8	hSpCas9	negative selection	10683678
53250852	53250875	X	-	28162770	SKM1	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.001120539893915251	[90]	[160]	0	hSpCas9	negative selection	10683679
53250368	53250391	X	-	28162770	PL21	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	0.9598252851556096	[188]	[159]	7	hSpCas9	negative selection	10853036
53250780	53250803	X	+	28162770	PL21	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	1.0818196473005588	[126]	[116]	8	hSpCas9	negative selection	10853037
53255976	53255999	X	+	28162770	PL21	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	1.771926726462743	[219]	[326]	9	hSpCas9	negative selection	10853038
53255926	53255949	X	+	28162770	PL21	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	0.32887292861152284	[299]	[163]	3	hSpCas9	negative selection	10853039
53255910	53255933	X	+	28162770	PL21	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.24399390407874777	[323]	[166]	2	hSpCas9	negative selection	10853040
53254769	53254792	X	+	28162770	PL21	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.641845064230244	[401]	[272]	5	hSpCas9	negative selection	10853041
53251111	53251134	X	+	28162770	PL21	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	0.6992413785566384	[74]	[52]	6	hSpCas9	negative selection	10853042
53251057	53251080	X	-	28162770	PL21	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	0.37493669109879146	[426]	[240]	3	hSpCas9	negative selection	10853043
53250900	53250923	X	+	28162770	PL21	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-2.5003001036517727	[12]	[0]	-9	hSpCas9	negative selection	10853044
53250852	53250875	X	-	28162770	PL21	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.024500961852614078	[252]	[111]	0	hSpCas9	negative selection	10853045
53250368	53250391	X	-	28162770	P31FUJ	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	0.7368241465421027	[167]	[328]	8	hSpCas9	negative selection	11022402
53250780	53250803	X	+	28162770	P31FUJ	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-0.16319673692851197	[262]	[275]	-1	hSpCas9	negative selection	11022403
53255976	53255999	X	+	28162770	P31FUJ	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	-0.21457844579547125	[235]	[238]	-2	hSpCas9	negative selection	11022404
53255926	53255949	X	+	28162770	P31FUJ	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	-0.29313273861570033	[292]	[280]	-3	hSpCas9	negative selection	11022405
53255910	53255933	X	+	28162770	P31FUJ	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.35700969596817345	[395]	[595]	4	hSpCas9	negative selection	11022406
53254769	53254792	X	+	28162770	P31FUJ	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.760938805113939	[461]	[919]	8	hSpCas9	negative selection	11022407
53251111	53251134	X	+	28162770	P31FUJ	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	0.7330899412653571	[106]	[208]	8	hSpCas9	negative selection	11022408
53251057	53251080	X	-	28162770	P31FUJ	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	0.09299741485354374	[520]	[652]	0	hSpCas9	negative selection	11022409
53250900	53250923	X	+	28162770	P31FUJ	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-0.6478397036932222	[7]	[5]	-5	hSpCas9	negative selection	11022410
53250852	53250875	X	-	28162770	P31FUJ	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.4331668594525677	[403]	[640]	5	hSpCas9	negative selection	11022411
53250368	53250391	X	-	28162770	OCIAML5	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	0.7460114296474174	[72]	[220]	6	hSpCas9	negative selection	11191768
53250780	53250803	X	+	28162770	OCIAML5	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-0.01507215836651886	[116]	[208]	0	hSpCas9	negative selection	11191769
53255976	53255999	X	+	28162770	OCIAML5	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	0.25731688864326463	[145]	[314]	2	hSpCas9	negative selection	11191770
53255926	53255949	X	+	28162770	OCIAML5	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	-0.008792074551450035	[135]	[243]	0	hSpCas9	negative selection	11191771
53255910	53255933	X	+	28162770	OCIAML5	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.5474300775190686	[209]	[553]	5	hSpCas9	negative selection	11191772
53254769	53254792	X	+	28162770	OCIAML5	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.6465116239575498	[194]	[550]	5	hSpCas9	negative selection	11191773
53251111	53251134	X	+	28162770	OCIAML5	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	1.6636332674200456	[31]	[182]	9	hSpCas9	negative selection	11191774
53251057	53251080	X	-	28162770	OCIAML5	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	-0.14515821055397082	[290]	[474]	-1	hSpCas9	negative selection	11191775
53250900	53250923	X	+	28162770	OCIAML5	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-3.1739946657513594	[4]	[0]	-9	hSpCas9	negative selection	11191776
53250852	53250875	X	-	28162770	OCIAML5	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.6060659076216766	[201]	[554]	5	hSpCas9	negative selection	11191777
53250368	53250391	X	-	28162770	EOL1	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	-0.26747100072239455	[328]	[143]	-2	hSpCas9	negative selection	11361134
53250780	53250803	X	+	28162770	EOL1	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	1.579636358682333	[173]	[273]	9	hSpCas9	negative selection	11361135
53255976	53255999	X	+	28162770	EOL1	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	-0.29914848631275864	[368]	[157]	-2	hSpCas9	negative selection	11361136
53255926	53255949	X	+	28162770	EOL1	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	0.11000451854339699	[502]	[285]	1	hSpCas9	negative selection	11361137
53255910	53255933	X	+	28162770	EOL1	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.35258711658325637	[717]	[482]	3	hSpCas9	negative selection	11361138
53254769	53254792	X	+	28162770	EOL1	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.03299449902884488	[806]	[434]	0	hSpCas9	negative selection	11361139
53251111	53251134	X	+	28162770	EOL1	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	0.3460115400088113	[111]	[74]	3	hSpCas9	negative selection	11361140
53251057	53251080	X	-	28162770	EOL1	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	0.33431032880870415	[547]	[363]	3	hSpCas9	negative selection	11361141
53250900	53250923	X	+	28162770	EOL1	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-3.162915069679805	[16]	[0]	-9	hSpCas9	negative selection	11361142
53250852	53250875	X	-	28162770	EOL1	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.7615735603044813	[439]	[392]	6	hSpCas9	negative selection	11361143
53250368	53250391	X	-	28162770	MOLM13	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	0.8473411775529168	[235]	[306]	6	hSpCas9	negative selection	11530500
53250780	53250803	X	+	28162770	MOLM13	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-0.1481000147972017	[140]	[91]	-1	hSpCas9	negative selection	11530501
53255976	53255999	X	+	28162770	MOLM13	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	0.8124189053690736	[303]	[385]	6	hSpCas9	negative selection	11530502
53255926	53255949	X	+	28162770	MOLM13	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	0.6594886493354236	[344]	[393]	5	hSpCas9	negative selection	11530503
53255910	53255933	X	+	28162770	MOLM13	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	1.093493866763081	[489]	[755]	8	hSpCas9	negative selection	11530504
53254769	53254792	X	+	28162770	MOLM13	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.7088974810483739	[681]	[805]	5	hSpCas9	negative selection	11530505
53251111	53251134	X	+	28162770	MOLM13	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	0.14935986311908134	[105]	[84]	1	hSpCas9	negative selection	11530506
53251057	53251080	X	-	28162770	MOLM13	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	-0.7223808892099137	[606]	[265]	-4	hSpCas9	negative selection	11530507
53250900	53250923	X	+	28162770	MOLM13	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-3.232550336596514	[12]	[0]	-8	hSpCas9	negative selection	11530508
53250852	53250875	X	-	28162770	MOLM13	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.4486103190496956	[451]	[445]	3	hSpCas9	negative selection	11530509
53250368	53250391	X	-	28162770	HEL	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	1.4574732844235587	[194]	[342]	9	hSpCas9	negative selection	11699866
53250780	53250803	X	+	28162770	HEL	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-0.15272241147599375	[150]	[86]	-1	hSpCas9	negative selection	11699867
53255976	53255999	X	+	28162770	HEL	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	1.0932750125005872	[280]	[383]	8	hSpCas9	negative selection	11699868
53255926	53255949	X	+	28162770	HEL	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	0.8702426671544042	[321]	[376]	7	hSpCas9	negative selection	11699869
53255910	53255933	X	+	28162770	HEL	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.8007145248410344	[457]	[510]	7	hSpCas9	negative selection	11699870
53254769	53254792	X	+	28162770	HEL	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.7111886188769485	[637]	[668]	6	hSpCas9	negative selection	11699871
53251111	53251134	X	+	28162770	HEL	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	-0.29586062333549945	[68]	[35]	-2	hSpCas9	negative selection	11699872
53251057	53251080	X	-	28162770	HEL	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	-0.32902748727069897	[505]	[257]	-2	hSpCas9	negative selection	11699873
53250900	53250923	X	+	28162770	HEL	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-2.6791892628870055	[9]	[0]	-8	hSpCas9	negative selection	11699874
53250852	53250875	X	-	28162770	HEL	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	-0.11164920848566712	[360]	[213]	-1	hSpCas9	negative selection	11699875
53250368	53250391	X	-	28162770	MV411	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	0.34243406471852217	[190]	[203]	3	hSpCas9	negative selection	11869232
53250780	53250803	X	+	28162770	MV411	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	0.010042966107080886	[144]	[122]	0	hSpCas9	negative selection	11869233
53255976	53255999	X	+	28162770	MV411	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	0.8053161723013074	[232]	[342]	7	hSpCas9	negative selection	11869234
53255926	53255949	X	+	28162770	MV411	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	-0.010987601798429003	[249]	[208]	0	hSpCas9	negative selection	11869235
53255910	53255933	X	+	28162770	MV411	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.7612390225826926	[373]	[533]	7	hSpCas9	negative selection	11869236
53254769	53254792	X	+	28162770	MV411	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.854493822354548	[431]	[657]	7	hSpCas9	negative selection	11869237
53251111	53251134	X	+	28162770	MV411	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	0.31782687867417314	[59]	[62]	3	hSpCas9	negative selection	11869238
53251057	53251080	X	-	28162770	MV411	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	0.39908525685298013	[405]	[450]	3	hSpCas9	negative selection	11869239
53250900	53250923	X	+	28162770	MV411	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	1.2474375507827755	[2]	[5]	9	hSpCas9	negative selection	11869240
53250852	53250875	X	-	28162770	MV411	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.5874121010875913	[285]	[361]	5	hSpCas9	negative selection	11869241
53250368	53250391	X	-	28162770	MONOMAC1	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	-0.3399948009015967	[105]	[95]	-3	hSpCas9	negative selection	12038598
53250780	53250803	X	+	28162770	MONOMAC1	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	0.027523410959604533	[94]	[110]	0	hSpCas9	negative selection	12038599
53255976	53255999	X	+	28162770	MONOMAC1	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	0.7874223020446682	[139]	[276]	7	hSpCas9	negative selection	12038600
53255926	53255949	X	+	28162770	MONOMAC1	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	-0.16504673281511684	[222]	[227]	-1	hSpCas9	negative selection	12038601
53255910	53255933	X	+	28162770	MONOMAC1	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	-0.17376706773670658	[245]	[249]	-1	hSpCas9	negative selection	12038602
53254769	53254792	X	+	28162770	MONOMAC1	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.552984899932099	[307]	[517]	5	hSpCas9	negative selection	12038603
53251111	53251134	X	+	28162770	MONOMAC1	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	1.46884564904517	[51]	[164]	9	hSpCas9	negative selection	12038604
53251057	53251080	X	-	28162770	MONOMAC1	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	-0.3318612706136074	[268]	[244]	-3	hSpCas9	negative selection	12038605
53250900	53250923	X	+	28162770	MONOMAC1	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	1.165533232325155	[6]	[17]	8	hSpCas9	negative selection	12038606
53250852	53250875	X	-	28162770	MONOMAC1	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.6798149221675815	[164]	[302]	6	hSpCas9	negative selection	12038607
53250368	53250391	X	-	28162770	OCIAML2	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	0.6780474424961118	[37]	[336]	6	hSpCas9	negative selection	12207964
53250780	53250803	X	+	28162770	OCIAML2	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	0.2572906293210379	[23]	[158]	2	hSpCas9	negative selection	12207965
53255976	53255999	X	+	28162770	OCIAML2	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	-0.027023173766546615	[49]	[271]	0	hSpCas9	negative selection	12207966
53255926	53255949	X	+	28162770	OCIAML2	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	-0.20159667878692428	[49]	[240]	-2	hSpCas9	negative selection	12207967
53255910	53255933	X	+	28162770	OCIAML2	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.33397448579940847	[74]	[523]	3	hSpCas9	negative selection	12207968
53254769	53254792	X	+	28162770	OCIAML2	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.6992951762001511	[77]	[701]	6	hSpCas9	negative selection	12207969
53251111	53251134	X	+	28162770	OCIAML2	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	0.45828707669635604	[12]	[98]	4	hSpCas9	negative selection	12207970
53251057	53251080	X	-	28162770	OCIAML2	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	0.49701480144545374	[61]	[484]	5	hSpCas9	negative selection	12207971
53250900	53250923	X	+	28162770	OCIAML2	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-4.4706298252421615	[3]	[0]	-9	hSpCas9	negative selection	12207972
53250852	53250875	X	-	28162770	OCIAML2	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.43451098841639757	[54]	[411]	4	hSpCas9	negative selection	12207973
53250368	53250391	X	-	28162770	OCIAML3	viability	TGTGCAAGCAGACTTACCAGCGG	IQSEC2	ENSG00000124313	-0.719538522408022	[47]	[87]	-5	hSpCas9	negative selection	12377330
53250780	53250803	X	+	28162770	OCIAML3	viability	GGAGGCTCAATGGTAAGCAGGGG	IQSEC2	ENSG00000124313	-0.23326029654627273	[43]	[112]	-2	hSpCas9	negative selection	12377331
53255976	53255999	X	+	28162770	OCIAML3	viability	GCAGCTGGCTCAGCCGGTAGGGG	IQSEC2	ENSG00000124313	0.048670358253280435	[48]	[152]	0	hSpCas9	negative selection	12377332
53255926	53255949	X	+	28162770	OCIAML3	viability	GGGAAGGCCCACTCCAGCAGGGG	IQSEC2	ENSG00000124313	-0.9936150990334011	[92]	[140]	-6	hSpCas9	negative selection	12377333
53255910	53255933	X	+	28162770	OCIAML3	viability	GTGCCCGCTGAGCCCAGGGAAGG	IQSEC2	ENSG00000124313	0.6614930928242232	[79]	[381]	6	hSpCas9	negative selection	12377334
53254769	53254792	X	+	28162770	OCIAML3	viability	TGTTGGAAAGGATGATGCGGCGG	IQSEC2	ENSG00000124313	0.018066706014234102	[122]	[375]	0	hSpCas9	negative selection	12377335
53251111	53251134	X	+	28162770	OCIAML3	viability	CAGACATGGGCCCTGACGGGTGG	IQSEC2	ENSG00000124313	0.4517960492889618	[30]	[127]	4	hSpCas9	negative selection	12377336
53251057	53251080	X	-	28162770	OCIAML3	viability	GGAGTCAAAGGAACAGCAAGAGG	IQSEC2	ENSG00000124313	1.0044003914619444	[88]	[538]	8	hSpCas9	negative selection	12377337
53250900	53250923	X	+	28162770	OCIAML3	viability	GGCACTGGTGGAGGAACTGGCGG	IQSEC2	ENSG00000124313	-2.594007640324163	[1]	[0]	-9	hSpCas9	negative selection	12377338
53250852	53250875	X	-	28162770	OCIAML3	viability	CGTGAGGAAGGCACTCGCAGGGG	IQSEC2	ENSG00000124313	0.01528418975873358	[97]	[298]	0	hSpCas9	negative selection	12377339