Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 8660
• Symbol: IRS2
• Description: insulin receptor substrate 2

DataSource: http://genomecrispr.dkfz.de/#!/results/IRS2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
109783933	109783956	13	+	26472758	Jiyoye	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	2.2145303035634774	[23]	[83]	9	hSpCas9	negative selection	79282
109784163	109784186	13	-	26472758	Jiyoye	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-1.9591468327399424	[329]	[63]	-8	hSpCas9	negative selection	79283
109783694	109783717	13	+	26472758	Jiyoye	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-0.0714782170689422	[84]	[60]	0	hSpCas9	negative selection	79284
109782785	109782808	13	+	26472758	Jiyoye	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	2.9396704623328938	[13]	[80]	9	hSpCas9	negative selection	79285
109785681	109785704	13	-	26472758	Jiyoye	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	-1.6077749599600981	[96]	[23]	-8	hSpCas9	negative selection	79286
109785297	109785320	13	+	26472758	Jiyoye	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	0.24632137047855773	[217]	[194]	2	hSpCas9	negative selection	79287
109785234	109785257	13	+	26472758	Jiyoye	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	0.7243655573865726	[60]	[75]	5	hSpCas9	negative selection	79288
109785060	109785083	13	+	26472758	Jiyoye	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	-0.9052089407106182	[225]	[90]	-6	hSpCas9	negative selection	79289
109784505	109784528	13	+	26472758	Jiyoye	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	2.4071753815058736	[4]	[19]	9	hSpCas9	negative selection	79290
109784176	109784199	13	+	26472758	Jiyoye	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	-0.23246421183559685	[362]	[232]	-2	hSpCas9	negative selection	79291
109783933	109783956	13	+	26472758	KBM7	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	0.48864974977517023	[363,259]	[215,191]	5	hSpCas9	negative selection	270400
109784163	109784186	13	-	26472758	KBM7	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-0.7867817526813556	[806,644]	[166,222]	-6	hSpCas9	negative selection	270401
109783694	109783717	13	+	26472758	KBM7	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	0.32183870320760066	[155,175]	[114,83]	3	hSpCas9	negative selection	270402
109782785	109782808	13	+	26472758	KBM7	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	0.08503710322236246	[116,84]	[62,37]	0	hSpCas9	negative selection	270403
109785681	109785704	13	-	26472758	KBM7	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	1.0484067070170249	[156,113]	[228,41]	9	hSpCas9	negative selection	270404
109785297	109785320	13	+	26472758	KBM7	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	0.0671590801868287	[1072,691]	[488,371]	0	hSpCas9	negative selection	270405
109785234	109785257	13	+	26472758	KBM7	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	0.6299767082170507	[187,154]	[120,126]	7	hSpCas9	negative selection	270406
109785060	109785083	13	+	26472758	KBM7	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	0.7074138405519578	[776,761]	[704,492]	7	hSpCas9	negative selection	270407
109784505	109784528	13	+	26472758	KBM7	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	1.7456079217952243	[116,42]	[105,133]	9	hSpCas9	negative selection	270408
109784176	109784199	13	+	26472758	KBM7	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	0.3069632016839514	[1037,1171]	[510,773]	3	hSpCas9	negative selection	270409
109783933	109783956	13	+	26472758	Raji	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	-0.2383913014681307	[121]	[23]	-2	hSpCas9	negative selection	461518
109784163	109784186	13	-	26472758	Raji	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-1.4369369808502106	[524]	[44]	-7	hSpCas9	negative selection	461519
109783694	109783717	13	+	26472758	Raji	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-0.8926164646264005	[103]	[12]	-6	hSpCas9	negative selection	461520
109782785	109782808	13	+	26472758	Raji	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	1.942324289103103	[36]	[32]	9	hSpCas9	negative selection	461521
109785681	109785704	13	-	26472758	Raji	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	0.6870517364252428	[90]	[33]	6	hSpCas9	negative selection	461522
109785297	109785320	13	+	26472758	Raji	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	0.26378509271616646	[523]	[145]	2	hSpCas9	negative selection	461523
109785234	109785257	13	+	26472758	Raji	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	0.3891545037889791	[101]	[30]	3	hSpCas9	negative selection	461524
109785060	109785083	13	+	26472758	Raji	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	0.14055039930879898	[472]	[120]	1	hSpCas9	negative selection	461525
109784505	109784528	13	+	26472758	Raji	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	0.8372943720058552	[40]	[16]	7	hSpCas9	negative selection	461526
109784176	109784199	13	+	26472758	Raji	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	0.11108750413701829	[777]	[194]	1	hSpCas9	negative selection	461527
109783933	109783956	13	+	26472758	K562	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	0.535720858523046	[218]	[267]	4	hSpCas9	negative selection	652636
109784163	109784186	13	-	26472758	K562	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-1.9984377962297166	[780]	[164]	-7	hSpCas9	negative selection	652637
109783694	109783717	13	+	26472758	K562	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-1.1761569551538267	[173]	[64]	-6	hSpCas9	negative selection	652638
109782785	109782808	13	+	26472758	K562	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	1.4668111490028946	[86]	[202]	9	hSpCas9	negative selection	652639
109785681	109785704	13	-	26472758	K562	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	0.969311489532078	[143]	[237]	7	hSpCas9	negative selection	652640
109785297	109785320	13	+	26472758	K562	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-0.5522156920256126	[904]	[520]	-3	hSpCas9	negative selection	652641
109785234	109785257	13	+	26472758	K562	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	0.36388239426801827	[138]	[150]	3	hSpCas9	negative selection	652642
109785060	109785083	13	+	26472758	K562	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	-0.5750090266917323	[719]	[407]	-4	hSpCas9	negative selection	652643
109784505	109784528	13	+	26472758	K562	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	1.3063464768096487	[56]	[118]	9	hSpCas9	negative selection	652644
109784176	109784199	13	+	26472758	K562	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	-0.14290248319637766	[1116]	[853]	-1	hSpCas9	negative selection	652645
109784184	109784207	13	+	26627737	DLD1	viability	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	0.5177520779235848	[384]	[147,243,133]	5	hSpCas9	negative selection	786153
109784380	109784403	13	-	26627737	DLD1	viability	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	0.40799378334232705	[870]	[208,439,427]	4	hSpCas9	negative selection	786154
109785372	109785395	13	+	26627737	DLD1	viability	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.4518789084185493	[772]	[258,504,247]	4	hSpCas9	negative selection	786155
109785624	109785647	13	+	26627737	DLD1	viability	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-0.24367381724788229	[1794]	[822,361,263]	-3	hSpCas9	negative selection	786156
109785657	109785680	13	-	26627737	DLD1	viability	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	1.1036462223292776	[309]	[178,185,251]	8	hSpCas9	negative selection	786157
109785893	109785916	13	-	26627737	DLD1	viability	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	0.1096928756551866	[658]	[164,197,291]	1	hSpCas9	negative selection	786158
109784184	109784207	13	+	26627737	GBM cells	viability after 5 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-1.5517475341238798	[245]	[57,31]	-9	hSpCas9	negative selection	868468
109784380	109784403	13	-	26627737	GBM cells	viability after 5 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-0.9480417504686014	[276]	[89,63]	-9	hSpCas9	negative selection	868469
109785372	109785395	13	+	26627737	GBM cells	viability after 5 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.11085029143684155	[454]	[260,265]	1	hSpCas9	negative selection	868470
109785624	109785647	13	+	26627737	GBM cells	viability after 5 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-0.5183414496429768	[433]	[189,134]	-7	hSpCas9	negative selection	868471
109785657	109785680	13	-	26627737	GBM cells	viability after 5 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-1.0945728181556402	[220]	[58,51]	-9	hSpCas9	negative selection	868472
109785893	109785916	13	-	26627737	GBM cells	viability after 5 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-0.06978999462477581	[227]	[122,109]	-1	hSpCas9	negative selection	868473
109784184	109784207	13	+	26627737	GBM cells	viability after 13 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-0.9162030204483469	[245]	[78,63]	-8	hSpCas9	negative selection	950783
109784380	109784403	13	-	26627737	GBM cells	viability after 13 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-0.7829761121208128	[276]	[88,85]	-7	hSpCas9	negative selection	950784
109785372	109785395	13	+	26627737	GBM cells	viability after 13 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	-0.06156444805423322	[454]	[251,223]	0	hSpCas9	negative selection	950785
109785624	109785647	13	+	26627737	GBM cells	viability after 13 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-0.4655713320549743	[433]	[271,87]	-5	hSpCas9	negative selection	950786
109785657	109785680	13	-	26627737	GBM cells	viability after 13 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-1.0745853502481975	[220]	[62,51]	-8	hSpCas9	negative selection	950787
109785893	109785916	13	-	26627737	GBM cells	viability after 13 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-0.34432724375561896	[227]	[81,109]	-4	hSpCas9	negative selection	950788
109784184	109784207	13	+	26627737	GBM cells	viability after 21 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-2.08449248481374	[245]	[42,20]	-9	hSpCas9	negative selection	1033098
109784380	109784403	13	-	26627737	GBM cells	viability after 21 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-1.1287062950885416	[276]	[72,64]	-7	hSpCas9	negative selection	1033099
109785372	109785395	13	+	26627737	GBM cells	viability after 21 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	-0.23883604038802564	[454]	[209,208]	-2	hSpCas9	negative selection	1033100
109785624	109785647	13	+	26627737	GBM cells	viability after 21 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-1.1182900420764186	[433]	[105,110]	-7	hSpCas9	negative selection	1033101
109785657	109785680	13	-	26627737	GBM cells	viability after 21 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-0.25757489778982856	[220]	[101,98]	-2	hSpCas9	negative selection	1033102
109785893	109785916	13	-	26627737	GBM cells	viability after 21 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-0.27536773399079273	[227]	[105,98]	-3	hSpCas9	negative selection	1033103
109784184	109784207	13	+	26627737	RPE1	viability after 9 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-0.7756650294041811	[1230]	[63,432]	-5	hSpCas9	negative selection	1115413
109784380	109784403	13	-	26627737	RPE1	viability after 9 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-0.5694352351224344	[997]	[234,178]	-4	hSpCas9	negative selection	1115414
109785372	109785395	13	+	26627737	RPE1	viability after 9 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.5460040660982686	[1377]	[566,710]	4	hSpCas9	negative selection	1115415
109785624	109785647	13	+	26627737	RPE1	viability after 9 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	1.1050385864838659	[1054]	[475,1012]	6	hSpCas9	negative selection	1115416
109785657	109785680	13	-	26627737	RPE1	viability after 9 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-0.42738411373051827	[1419]	[275,400]	-3	hSpCas9	negative selection	1115417
109785893	109785916	13	-	26627737	RPE1	viability after 9 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-1.2854126069687788	[780]	[67,141]	-7	hSpCas9	negative selection	1115418
109784184	109784207	13	+	26627737	RPE1	viability after 12 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-1.0401237188884687	[1230]	[69,256]	-6	hSpCas9	negative selection	1197728
109784380	109784403	13	-	26627737	RPE1	viability after 12 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-0.7029627180699551	[997]	[205,120]	-5	hSpCas9	negative selection	1197729
109785372	109785395	13	+	26627737	RPE1	viability after 12 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.7044488487125447	[1377]	[527,682]	4	hSpCas9	negative selection	1197730
109785624	109785647	13	+	26627737	RPE1	viability after 12 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	0.33597849701461513	[1054]	[213,509]	2	hSpCas9	negative selection	1197731
109785657	109785680	13	-	26627737	RPE1	viability after 12 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-0.14678491138132066	[1419]	[228,466]	-1	hSpCas9	negative selection	1197732
109785893	109785916	13	-	26627737	RPE1	viability after 12 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-0.9042410171945693	[780]	[132,89]	-6	hSpCas9	negative selection	1197733
109784184	109784207	13	+	26627737	RPE1	viability after 15 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-1.8798632905270527	[1230]	[59,127]	-8	hSpCas9	negative selection	1280043
109784380	109784403	13	-	26627737	RPE1	viability after 15 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-0.16303848960223657	[997]	[243,259]	-1	hSpCas9	negative selection	1280044
109785372	109785395	13	+	26627737	RPE1	viability after 15 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.6310258683557202	[1377]	[452,748]	4	hSpCas9	negative selection	1280045
109785624	109785647	13	+	26627737	RPE1	viability after 15 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	0.2350620664602362	[1054]	[252,445]	1	hSpCas9	negative selection	1280046
109785657	109785680	13	-	26627737	RPE1	viability after 15 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-0.42938933511064925	[1419]	[197,394]	-3	hSpCas9	negative selection	1280047
109785893	109785916	13	-	26627737	RPE1	viability after 15 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-0.8291855410917304	[780]	[160,88]	-5	hSpCas9	negative selection	1280048
109784184	109784207	13	+	26627737	RPE1	viability after 18 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-1.423350436243645	[1230]	[46,205]	-7	hSpCas9	negative selection	1362358
109784380	109784403	13	-	26627737	RPE1	viability after 18 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	0.3427042168527125	[997]	[269,417]	2	hSpCas9	negative selection	1362359
109785372	109785395	13	+	26627737	RPE1	viability after 18 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.736605148560949	[1377]	[550,692]	4	hSpCas9	negative selection	1362360
109785624	109785647	13	+	26627737	RPE1	viability after 18 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	0.40913661618046504	[1054]	[175,593]	2	hSpCas9	negative selection	1362361
109785657	109785680	13	-	26627737	RPE1	viability after 18 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-0.12514164829196883	[1419]	[303,401]	-1	hSpCas9	negative selection	1362362
109785893	109785916	13	-	26627737	RPE1	viability after 18 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-1.1869837428519692	[780]	[50,136]	-6	hSpCas9	negative selection	1362363
109784184	109784207	13	+	26627737	HeLa	viability after 8 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-0.2622326395375101	[386]	[315,34,110]	-3	hSpCas9	negative selection	1444673
109784380	109784403	13	-	26627737	HeLa	viability after 8 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-0.39495441411583204	[439]	[188,46,205]	-4	hSpCas9	negative selection	1444674
109785372	109785395	13	+	26627737	HeLa	viability after 8 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.23505920032178484	[878]	[612,258,509]	2	hSpCas9	negative selection	1444675
109785624	109785647	13	+	26627737	HeLa	viability after 8 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-2.3564948593730177	[1340]	[197,13,145]	-9	hSpCas9	negative selection	1444676
109785657	109785680	13	-	26627737	HeLa	viability after 8 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-0.9467655668267845	[234]	[33,112,10]	-7	hSpCas9	negative selection	1444677
109785893	109785916	13	-	26627737	HeLa	viability after 8 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-1.3850003614347013	[452]	[56,54,107]	-8	hSpCas9	negative selection	1444678
109784184	109784207	13	+	26627737	HeLa	viability after 12 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-1.127399239664334	[386]	[6,126,77]	-8	hSpCas9	negative selection	1526988
109784380	109784403	13	-	26627737	HeLa	viability after 12 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-0.01951423296729779	[439]	[219,229,83]	0	hSpCas9	negative selection	1526989
109785372	109785395	13	+	26627737	HeLa	viability after 12 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.26565791079404666	[878]	[712,305,312]	2	hSpCas9	negative selection	1526990
109785624	109785647	13	+	26627737	HeLa	viability after 12 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-2.0749649232990146	[1340]	[263,97,39]	-9	hSpCas9	negative selection	1526991
109785657	109785680	13	-	26627737	HeLa	viability after 12 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-1.3494926328135	[234]	[32,20,61]	-8	hSpCas9	negative selection	1526992
109785893	109785916	13	-	26627737	HeLa	viability after 12 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-2.806231641926823	[452]	[29,20,29]	-9	hSpCas9	negative selection	1526993
109784184	109784207	13	+	26627737	HeLa	viability after 15 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-1.0803348380329172	[386]	[81,59,81]	-7	hSpCas9	negative selection	1609303
109784380	109784403	13	-	26627737	HeLa	viability after 15 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-0.5561118828555857	[439]	[109,213,34]	-5	hSpCas9	negative selection	1609304
109785372	109785395	13	+	26627737	HeLa	viability after 15 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.08160953693965234	[878]	[430,377,321]	0	hSpCas9	negative selection	1609305
109785624	109785647	13	+	26627737	HeLa	viability after 15 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-2.026382864469524	[1340]	[149,175,70]	-9	hSpCas9	negative selection	1609306
109785657	109785680	13	-	26627737	HeLa	viability after 15 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-1.452908000327254	[234]	[20,0,86]	-8	hSpCas9	negative selection	1609307
109785893	109785916	13	-	26627737	HeLa	viability after 15 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-1.5262908887009425	[452]	[27,106,56]	-8	hSpCas9	negative selection	1609308
109784184	109784207	13	+	26627737	HeLa	viability after 18 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-1.0310609626535419	[386]	[58,50,81]	-7	hSpCas9	negative selection	1691618
109784380	109784403	13	-	26627737	HeLa	viability after 18 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-0.524584981861699	[439]	[79,175,34]	-4	hSpCas9	negative selection	1691619
109785372	109785395	13	+	26627737	HeLa	viability after 18 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.08477518037049281	[878]	[293,308,321]	0	hSpCas9	negative selection	1691620
109785624	109785647	13	+	26627737	HeLa	viability after 18 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-2.0024032388107504	[1340]	[99,151,70]	-9	hSpCas9	negative selection	1691621
109785657	109785680	13	-	26627737	HeLa	viability after 18 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-1.4100994710005423	[234]	[15,0,86]	-8	hSpCas9	negative selection	1691622
109785893	109785916	13	-	26627737	HeLa	viability after 18 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-1.5813837309777778	[452]	[16,84,56]	-8	hSpCas9	negative selection	1691623
109784184	109784207	13	+	26627737	HCT116	viability after 6 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	0.0798762776971973	[507]	[37,109]	0	hSpCas9	negative selection	1773933
109784380	109784403	13	-	26627737	HCT116	viability after 6 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	0.07368684591073227	[735]	[182,87]	0	hSpCas9	negative selection	1773934
109785372	109785395	13	+	26627737	HCT116	viability after 6 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.1336482603064384	[1441]	[336,199]	0	hSpCas9	negative selection	1773935
109785624	109785647	13	+	26627737	HCT116	viability after 6 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	0.6537077862866636	[1794]	[684,310]	3	hSpCas9	negative selection	1773936
109785657	109785680	13	-	26627737	HCT116	viability after 6 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	0.1804357385177306	[655]	[112,118]	1	hSpCas9	negative selection	1773937
109785893	109785916	13	-	26627737	HCT116	viability after 6 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-0.5652958188922206	[495]	[140,3]	-3	hSpCas9	negative selection	1773938
109784184	109784207	13	+	26627737	HCT116	viability after 8 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-1.6861052122738003	[403]	[37,100,67]	-9	hSpCas9	negative selection	1856248
109784380	109784403	13	-	26627737	HCT116	viability after 8 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	0.6410666777237943	[170]	[114,156,167]	6	hSpCas9	negative selection	1856249
109785372	109785395	13	+	26627737	HCT116	viability after 8 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.6106380721919272	[544]	[465,385,522]	6	hSpCas9	negative selection	1856250
109785624	109785647	13	+	26627737	HCT116	viability after 8 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	0.419524238896667	[491]	[489,313,286]	4	hSpCas9	negative selection	1856251
109785657	109785680	13	-	26627737	HCT116	viability after 8 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-0.2002781681216255	[359]	[46,235,231]	-2	hSpCas9	negative selection	1856252
109785893	109785916	13	-	26627737	HCT116	viability after 8 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	0.03881876762188485	[309]	[249,121,155]	0	hSpCas9	negative selection	1856253
109784184	109784207	13	+	26627737	HCT116	viability after 9 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	1.3991039986430274	[507]	[197,483]	8	hSpCas9	negative selection	1938563
109784380	109784403	13	-	26627737	HCT116	viability after 9 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	0.45978304568050143	[735]	[257,279]	3	hSpCas9	negative selection	1938564
109785372	109785395	13	+	26627737	HCT116	viability after 9 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	-0.2808956621198305	[1441]	[517,157]	-2	hSpCas9	negative selection	1938565
109785624	109785647	13	+	26627737	HCT116	viability after 9 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-0.01581572222071892	[1794]	[749,255]	0	hSpCas9	negative selection	1938566
109785657	109785680	13	-	26627737	HCT116	viability after 9 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-0.6982765412791999	[655]	[74,133]	-5	hSpCas9	negative selection	1938567
109785893	109785916	13	-	26627737	HCT116	viability after 9 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-1.3039788591454766	[495]	[99,16]	-7	hSpCas9	negative selection	1938568
109784184	109784207	13	+	26627737	HCT116	viability after 12 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-0.8243149051473084	[403]	[77,144,140]	-7	hSpCas9	negative selection	2020878
109784380	109784403	13	-	26627737	HCT116	viability after 12 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	0.641009524666405	[170]	[81,159,183]	6	hSpCas9	negative selection	2020879
109785372	109785395	13	+	26627737	HCT116	viability after 12 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.7036126280955951	[544]	[551,308,526]	6	hSpCas9	negative selection	2020880
109785624	109785647	13	+	26627737	HCT116	viability after 12 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	0.09349400669350927	[491]	[326,270,224]	1	hSpCas9	negative selection	2020881
109785657	109785680	13	-	26627737	HCT116	viability after 12 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-1.1670299464623173	[359]	[91,80,78]	-8	hSpCas9	negative selection	2020882
109785893	109785916	13	-	26627737	HCT116	viability after 12 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	0.21621562870431993	[309]	[253,144,161]	2	hSpCas9	negative selection	2020883
109784184	109784207	13	+	26627737	HCT116	viability after 15 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-0.6964544878642236	[403]	[100,230,92]	-6	hSpCas9	negative selection	2103193
109784380	109784403	13	-	26627737	HCT116	viability after 15 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-0.07124098745801921	[170]	[95,113,70]	0	hSpCas9	negative selection	2103194
109785372	109785395	13	+	26627737	HCT116	viability after 15 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.5760043584435056	[544]	[343,422,615]	5	hSpCas9	negative selection	2103195
109785624	109785647	13	+	26627737	HCT116	viability after 15 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	0.09875733203357728	[491]	[329,356,224]	1	hSpCas9	negative selection	2103196
109785657	109785680	13	-	26627737	HCT116	viability after 15 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-0.9977777300739099	[359]	[111,126,72]	-7	hSpCas9	negative selection	2103197
109785893	109785916	13	-	26627737	HCT116	viability after 15 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-0.5876687641279037	[309]	[176,106,78]	-6	hSpCas9	negative selection	2103198
109784184	109784207	13	+	26627737	HCT116	viability after 18 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-0.7063699974886686	[403]	[72,173,107]	-6	hSpCas9	negative selection	2185508
109784380	109784403	13	-	26627737	HCT116	viability after 18 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	0.3622324681629947	[170]	[130,42,150]	3	hSpCas9	negative selection	2185509
109785372	109785395	13	+	26627737	HCT116	viability after 18 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.910490292446433	[544]	[471,502,510]	7	hSpCas9	negative selection	2185510
109785624	109785647	13	+	26627737	HCT116	viability after 18 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	0.17160957756079542	[491]	[447,259,87]	1	hSpCas9	negative selection	2185511
109785657	109785680	13	-	26627737	HCT116	viability after 18 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-0.5476531428876106	[359]	[128,150,72]	-5	hSpCas9	negative selection	2185512
109785893	109785916	13	-	26627737	HCT116	viability after 18 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	0.27138019751408443	[309]	[237,145,159]	2	hSpCas9	negative selection	2185513
109775192	109775215	13	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCTGCCTCCCTGG	IRS2	ENSG00000185950	-0.8346021834980462	[246,704]	[74,41]	-5	dCas9-VP64	positive selection	2386365
109775192	109775215	13	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCTGCCTCCCTGG	IRS2	ENSG00000185950	0.6564409522361534	[325,125]	[135,99]	5	dCas9-VP64	positive selection	2481620
109785805	109785828	13	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACGAGAGCGAGAAAAAGTGGCGG	IRS2	ENSG00000185950	0.4620878615224725	[3,4]	[2,6]	8	hSpCas9	positive selection	2995992
109785235	109785258	13	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-0.3794915301346347	[2,2]	[0,2]	-5	hSpCas9	positive selection	2995993
109785609	109785632	13	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGGTCAGCGAGGGCCGCGCGG	IRS2	ENSG00000185950	-0.17410797440696435	[2,1]	[2,0]	-2	hSpCas9	positive selection	2995994
109785503	109785526	13	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGCTGTCCTCGGCCCCGGCGG	IRS2	ENSG00000185950	0.2901646719421655	[2,2]	[3,1]	6	hSpCas9	positive selection	2995995
109785805	109785828	13	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACGAGAGCGAGAAAAAGTGGCGG	IRS2	ENSG00000185950	-0.3379848756162724	[3,3]	[3,0]	-5	hSpCas9	positive selection	3063850
109785235	109785258	13	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	0.1036409285422757	[2,2]	[3,1]	1	hSpCas9	positive selection	3063851
109785609	109785632	13	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGGTCAGCGAGGGCCGCGCGG	IRS2	ENSG00000185950	-0.510053306939882	[2,2]	[1,0]	-7	hSpCas9	positive selection	3063852
109785503	109785526	13	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGCTGTCCTCGGCCCCGGCGG	IRS2	ENSG00000185950	-0.6049520359583519	[2,2]	[1,0]	-8	hSpCas9	positive selection	3063853
109785682	109785705		+	24336571	A375	resistance to PLX after 7 days	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.0038394055155430706	[2,4]	[3,3]	0	hSpCas9	positive selection	3121616
109785767	109785790		+	24336571	A375	resistance to PLX after 7 days	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	0.1256561017589698	[9,7]	[8,10]	4	hSpCas9	positive selection	3121617
109785682	109785705		+	24336571	A375	resistance to PLX after 14 days	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	0.4148465559152563	[2,3]	[1,1]	4	hSpCas9	positive selection	3179409
109785767	109785790		+	24336571	A375	resistance to PLX after 14 days	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	0.5071450999995873	[11,5]	[5,4]	5	hSpCas9	positive selection	3179410
109785682	109785705		+	24336571	A375	viability after 7 days	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.5224411855956954	[6]	[2,4]	-6	hSpCas9	negative selection	3237202
109785767	109785790		+	24336571	A375	viability after 7 days	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.5577679411431233	[13]	[9,7]	-7	hSpCas9	negative selection	3237203
109785682	109785705		+	24336571	A375	viability after 14 days	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.7249530776033553	[6]	[2,3]	-7	hSpCas9	negative selection	3294995
109785767	109785790		+	24336571	A375	viability after 14 days	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.5589184282142017	[13]	[11,5]	-6	hSpCas9	negative selection	3294996
109782733	109782756	13	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	0.7181674003378036	[92,92]	[0,0]	3	hSpCas9	positive selection	3374652
109785899	109785922	13	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	1.1698633701954957	[67,67]	[0,0]	5	hSpCas9	positive selection	3374653
109782630	109782653	13	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	1.2800462879459185	[62,62]	[0,0]	5	hSpCas9	positive selection	3374654
109785805	109785828	13	-	26780180	HT29	viability (Avana library 4 designs)	ACGAGAGCGAGAAAAAGTGGCGG	IRS2	ENSG00000185950	5.01895595048074	[]	[]	9	hSpCas9	negative selection	3433381
109785234	109785257	13	+	26780180	HT29	viability (Avana library 4 designs)	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	2.51896839784917	[]	[]	8	hSpCas9	negative selection	3433382
109785609	109785632	13	-	26780180	HT29	viability (Avana library 4 designs)	CCTGGTCAGCGAGGGCCGCGCGG	IRS2	ENSG00000185950	1.65338111653536	[]	[]	6	hSpCas9	negative selection	3433383
109785502	109785525	13	+	26780180	HT29	viability (Avana library 4 designs)	GTAGCTGTCCTCGGCCCCGGCGG	IRS2	ENSG00000185950	1.60480353759544	[]	[]	6	hSpCas9	negative selection	3433384
109785805	109785828	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACGAGAGCGAGAAAAAGTGGCGG	IRS2	ENSG00000185950	-7.96138371931129	[]	[]	-7	hSpCas9	negative selection	3519964
109785234	109785257	13	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-8.76761847724717	[]	[]	-7	hSpCas9	negative selection	3519965
109785609	109785632	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGTCAGCGAGGGCCGCGCGG	IRS2	ENSG00000185950	-5.75918243181598	[]	[]	-6	hSpCas9	negative selection	3519966
109785502	109785525	13	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGCTGTCCTCGGCCCCGGCGG	IRS2	ENSG00000185950	1.246851457371	[]	[]	1	hSpCas9	negative selection	3519967
109785124	109785147	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGTAAGAGCCAATCGTCGGGG	IRS2	ENSG00000185950	-1.09192621590571	[]	[]	-1	hSpCas9	negative selection	3519968
109785899	109785922	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	5.27112782246971	[]	[]	8	hSpCas9	negative selection	3519969
109785805	109785828	13	-	26780180	A375	viability (Avana lentiGuide)	ACGAGAGCGAGAAAAAGTGGCGG	IRS2	ENSG00000185950	12.6106190933542	[]	[]	7	hSpCas9	negative selection	3628623
109785234	109785257	13	+	26780180	A375	viability (Avana lentiGuide)	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	27.2445730442417	[]	[]	9	hSpCas9	negative selection	3628624
109785609	109785632	13	-	26780180	A375	viability (Avana lentiGuide)	CCTGGTCAGCGAGGGCCGCGCGG	IRS2	ENSG00000185950	12.6072920939866	[]	[]	7	hSpCas9	negative selection	3628625
109785502	109785525	13	+	26780180	A375	viability (Avana lentiGuide)	GTAGCTGTCCTCGGCCCCGGCGG	IRS2	ENSG00000185950	19.8853718774031	[]	[]	8	hSpCas9	negative selection	3628626
109785124	109785147	13	-	26780180	A375	viability (Avana lentiGuide)	GCAGTAAGAGCCAATCGTCGGGG	IRS2	ENSG00000185950	3.16872263040291	[]	[]	3	hSpCas9	negative selection	3628627
109785899	109785922	13	-	26780180	A375	viability (Avana lentiGuide)	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	3.4039863017265	[]	[]	3	hSpCas9	negative selection	3628628
109785805	109785828	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACGAGAGCGAGAAAAAGTGGCGG	IRS2	ENSG00000185950	-0.7849437558458909	[6]	[2,3]	-8	hSpCas9	positive selection	3737282
109785234	109785257	13	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-1.7727715557309787	[4]	[0,0]	-9	hSpCas9	positive selection	3737283
109785609	109785632	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGTCAGCGAGGGCCGCGCGG	IRS2	ENSG00000185950	0.12427929864645804	[3]	[4,2]	3	hSpCas9	positive selection	3737284
109785502	109785525	13	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGCTGTCCTCGGCCCCGGCGG	IRS2	ENSG00000185950	0.04977400242589302	[4]	[5,4]	1	hSpCas9	positive selection	3737285
109785124	109785147	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGTAAGAGCCAATCGTCGGGG	IRS2	ENSG00000185950	-0.022696004456988526	[5]	[4,4]	0	hSpCas9	positive selection	3737286
109785899	109785922	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.367227901833043	[4]	[5,5]	9	hSpCas9	positive selection	3737287
109785805	109785828	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACGAGAGCGAGAAAAAGTGGCGG	IRS2	ENSG00000185950	-0.07182413557263595	[6]	[4,5]	-1	hSpCas9	positive selection	3845889
109785234	109785257	13	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-0.8092664772618885	[4]	[1,1]	-7	hSpCas9	positive selection	3845890
109785609	109785632	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGTCAGCGAGGGCCGCGCGG	IRS2	ENSG00000185950	-0.9776748351500082	[4]	[0,2]	-8	hSpCas9	positive selection	3845891
109785502	109785525	13	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGCTGTCCTCGGCCCCGGCGG	IRS2	ENSG00000185950	-0.026031912038621735	[4]	[3,3]	0	hSpCas9	positive selection	3845892
109785124	109785147	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGTAAGAGCCAATCGTCGGGG	IRS2	ENSG00000185950	0.06180168585581386	[6]	[5,5]	1	hSpCas9	positive selection	3845893
109785899	109785922	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	-0.4489882365662893	[4]	[2,1]	-5	hSpCas9	positive selection	3845894
109785899	109785922	13	-	26780180	A375	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.995590146079003	[]	[]	4	hSpCas9	negative selection	3951908
109785682	109785705	13	+	26780180	A375	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	2.15689884788006	[]	[]	9	hSpCas9	negative selection	3951909
109783442	109783465	13	+	26780180	A375	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	1.68089527058656	[]	[]	9	hSpCas9	negative selection	3951910
109782733	109782756	13	-	26780180	A375	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	1.72160222660849	[]	[]	9	hSpCas9	negative selection	3951911
109782630	109782653	13	-	26780180	A375	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	1.06481665990641	[]	[]	5	hSpCas9	negative selection	3951912
109785767	109785790	13	+	26780180	A375	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	2.22653200195875	[]	[]	9	hSpCas9	negative selection	3951913
109785899	109785922	13	-	26780180	HT29	viability (GeCKOv2 library)	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.827193827395539	[]	[]	3	hSpCas9	negative selection	4059874
109785682	109785705	13	+	26780180	HT29	viability (GeCKOv2 library)	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	1.70155768673159	[]	[]	8	hSpCas9	negative selection	4059875
109783442	109783465	13	+	26780180	HT29	viability (GeCKOv2 library)	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	1.18980345709331	[]	[]	6	hSpCas9	negative selection	4059876
109782733	109782756	13	-	26780180	HT29	viability (GeCKOv2 library)	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	1.09119465396472	[]	[]	5	hSpCas9	negative selection	4059877
109782630	109782653	13	-	26780180	HT29	viability (GeCKOv2 library)	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.603407142616957	[]	[]	2	hSpCas9	negative selection	4059878
109785767	109785790	13	+	26780180	HT29	viability (GeCKOv2 library)	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	1.02580415101835	[]	[]	5	hSpCas9	negative selection	4059879
109785682	109785705	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.33530146859883625	[1]	[0,0]	-7	hSpCas9	positive selection	4145318
109785767	109785790	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	0.13990694765867193	[3]	[1,2]	3	hSpCas9	positive selection	4145319
109785682	109785705	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	0.3918842964741709	[2]	[0,2,2,0]	3	hSpCas9	positive selection	4209340
109785767	109785790	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.9481591361961763	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4209341
109785682	109785705	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.36028619127665307	[3]	[2,1]	-6	hSpCas9	positive selection	4277301
109785767	109785790	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.37916331523914976	[4]	[2,1]	-7	hSpCas9	positive selection	4277302
109783442	109783465	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.5716301978497791	[2]	[1,0]	-8	hSpCas9	positive selection	4277303
109782733	109782756	13	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.27699596542847105	[2]	[1,1]	-5	hSpCas9	positive selection	4341557
109785899	109785922	13	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	-0.10949895456140224	[1]	[2,0]	-2	hSpCas9	positive selection	4341558
109782630	109782653	13	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.28142822496462117	[1]	[1,1]	5	hSpCas9	positive selection	4341559
109784141	109784163	13	-	27760321	OCIAML3	viability	ACTACGGAGACATCGAGATCGG	IRS2	ENSG00000185950	-0.27622183275860634	[215,215]	[109,178]	-3	hSpCas9	negative selection	4410334
109784370	109784392	13	-	27760321	OCIAML3	viability	TCCTACCGCCGGGTCTCGGGGG	IRS2	ENSG00000185950	0.4455691311986123	[862,682]	[772,876]	5	hSpCas9	negative selection	4410335
109785115	109785137	13	+	27760321	OCIAML3	viability	GGCCGACGACCCCGACGATTGG	IRS2	ENSG00000185950	0.21488673632652566	[819,665]	[633,718]	2	hSpCas9	negative selection	4410336
109785397	109785419	13	+	27760321	OCIAML3	viability	CAGACGGTACACCCCCGTCAGG	IRS2	ENSG00000185950	0.15632898013390195	[738,570]	[551,585]	1	hSpCas9	negative selection	4410337
109785781	109785803	13	-	27760321	OCIAML3	viability	CAAGGCAGGCGCGCCGAAACGG	IRS2	ENSG00000185950	-0.6471586353335432	[276,184]	[102,127]	-6	hSpCas9	negative selection	4410338
109784141	109784163	13	-	27760321	OCIAML2	viability	ACTACGGAGACATCGAGATCGG	IRS2	ENSG00000185950	-0.4886013587226279	[215,215]	[111,141]	-5	hSpCas9	negative selection	4493797
109784370	109784392	13	-	27760321	OCIAML2	viability	TCCTACCGCCGGGTCTCGGGGG	IRS2	ENSG00000185950	-1.1907181785225212	[862,682]	[238,315]	-8	hSpCas9	negative selection	4493798
109785115	109785137	13	+	27760321	OCIAML2	viability	GGCCGACGACCCCGACGATTGG	IRS2	ENSG00000185950	-0.5846896101027622	[819,665]	[339,475]	-6	hSpCas9	negative selection	4493799
109785397	109785419	13	+	27760321	OCIAML2	viability	CAGACGGTACACCCCCGTCAGG	IRS2	ENSG00000185950	-1.0807147773357375	[738,570]	[249,246]	-7	hSpCas9	negative selection	4493800
109785781	109785803	13	-	27760321	OCIAML2	viability	CAAGGCAGGCGCGCCGAAACGG	IRS2	ENSG00000185950	-1.0791047411754404	[276,184]	[85,88]	-7	hSpCas9	negative selection	4493801
109784141	109784163	13	-	27760321	MV411	viability	ACTACGGAGACATCGAGATCGG	IRS2	ENSG00000185950	-0.671892384790189	[215,215]	[44,156]	-4	hSpCas9	negative selection	4577260
109784370	109784392	13	-	27760321	MV411	viability	TCCTACCGCCGGGTCTCGGGGG	IRS2	ENSG00000185950	0.42262009223797814	[862,682]	[477,981]	3	hSpCas9	negative selection	4577261
109785115	109785137	13	+	27760321	MV411	viability	GGCCGACGACCCCGACGATTGG	IRS2	ENSG00000185950	0.10536359249763982	[819,665]	[162,1067]	0	hSpCas9	negative selection	4577262
109785397	109785419	13	+	27760321	MV411	viability	CAGACGGTACACCCCCGTCAGG	IRS2	ENSG00000185950	0.008189932332135497	[738,570]	[608,164]	0	hSpCas9	negative selection	4577263
109785781	109785803	13	-	27760321	MV411	viability	CAAGGCAGGCGCGCCGAAACGG	IRS2	ENSG00000185950	-1.7476959449699276	[276,184]	[43,45]	-8	hSpCas9	negative selection	4577264
109784141	109784163	13	-	27760321	HL60	viability	ACTACGGAGACATCGAGATCGG	IRS2	ENSG00000185950	-1.1143116422355042	[215,215]	[40,124]	-8	hSpCas9	negative selection	4660723
109784370	109784392	13	-	27760321	HL60	viability	TCCTACCGCCGGGTCTCGGGGG	IRS2	ENSG00000185950	-1.0709706754156754	[862,682]	[370,221]	-8	hSpCas9	negative selection	4660724
109785115	109785137	13	+	27760321	HL60	viability	GGCCGACGACCCCGACGATTGG	IRS2	ENSG00000185950	-0.18349202347920457	[819,665]	[536,525]	-2	hSpCas9	negative selection	4660725
109785397	109785419	13	+	27760321	HL60	viability	CAGACGGTACACCCCCGTCAGG	IRS2	ENSG00000185950	-0.4538579821265265	[738,570]	[281,499]	-5	hSpCas9	negative selection	4660726
109785781	109785803	13	-	27760321	HL60	viability	CAAGGCAGGCGCGCCGAAACGG	IRS2	ENSG00000185950	-1.6742746136032347	[276,184]	[69,45]	-9	hSpCas9	negative selection	4660727
109784141	109784163	13	-	27760321	HT1080	viability	ACTACGGAGACATCGAGATCGG	IRS2	ENSG00000185950	-0.49362733177468776	[215,168]	[74,31]	-2	hSpCas9	negative selection	4744186
109784370	109784392	13	-	27760321	HT1080	viability	TCCTACCGCCGGGTCTCGGGGG	IRS2	ENSG00000185950	0.3831865493999639	[682,532]	[281,352]	2	hSpCas9	negative selection	4744187
109785115	109785137	13	+	27760321	HT1080	viability	GGCCGACGACCCCGACGATTGG	IRS2	ENSG00000185950	0.6915041850543984	[665,519]	[539,207]	3	hSpCas9	negative selection	4744188
109785397	109785419	13	+	27760321	HT1080	viability	CAGACGGTACACCCCCGTCAGG	IRS2	ENSG00000185950	0.2698206553698942	[570,445]	[143,353]	1	hSpCas9	negative selection	4744189
109785781	109785803	13	-	27760321	HT1080	viability	CAAGGCAGGCGCGCCGAAACGG	IRS2	ENSG00000185950	-0.7291980014362829	[184,144]	[21,58]	-3	hSpCas9	negative selection	4744190
109784141	109784163	13	-	27760321	HT29	viability after 7 days	ACTACGGAGACATCGAGATCGG	IRS2	ENSG00000185950	-0.26414387558885166	[215,168]	[218,165,233]	-4	hSpCas9	negative selection	4827649
109784370	109784392	13	-	27760321	HT29	viability after 7 days	TCCTACCGCCGGGTCTCGGGGG	IRS2	ENSG00000185950	0.28795461542948864	[682,532]	[1202,604,1084]	4	hSpCas9	negative selection	4827650
109785115	109785137	13	+	27760321	HT29	viability after 7 days	GGCCGACGACCCCGACGATTGG	IRS2	ENSG00000185950	0.2562159303534556	[665,519]	[889,875,959]	4	hSpCas9	negative selection	4827651
109785397	109785419	13	+	27760321	HT29	viability after 7 days	CAGACGGTACACCCCCGTCAGG	IRS2	ENSG00000185950	0.2241416352489658	[570,445]	[1217,442,695]	3	hSpCas9	negative selection	4827652
109785781	109785803	13	-	27760321	HT29	viability after 7 days	CAAGGCAGGCGCGCCGAAACGG	IRS2	ENSG00000185950	0.22392850958466348	[184,144]	[443,107,219]	3	hSpCas9	negative selection	4827653
109784141	109784163	13	-	27760321	HT29	viability after 25 days	ACTACGGAGACATCGAGATCGG	IRS2	ENSG00000185950	-0.26850960292334647	[215,168]	[124,237,188]	-3	hSpCas9	negative selection	4911112
109784370	109784392	13	-	27760321	HT29	viability after 25 days	TCCTACCGCCGGGTCTCGGGGG	IRS2	ENSG00000185950	-0.13574151814603808	[682,532]	[398,500,1054]	-1	hSpCas9	negative selection	4911113
109785115	109785137	13	+	27760321	HT29	viability after 25 days	GGCCGACGACCCCGACGATTGG	IRS2	ENSG00000185950	0.38208484568318335	[665,519]	[1074,765,784]	4	hSpCas9	negative selection	4911114
109785397	109785419	13	+	27760321	HT29	viability after 25 days	CAGACGGTACACCCCCGTCAGG	IRS2	ENSG00000185950	-0.24855257525039565	[570,445]	[505,588,356]	-3	hSpCas9	negative selection	4911115
109785781	109785803	13	-	27760321	HT29	viability after 25 days	CAAGGCAGGCGCGCCGAAACGG	IRS2	ENSG00000185950	-0.21130851813386853	[184,144]	[236,116,125]	-2	hSpCas9	negative selection	4911116
109784141	109784163	13	-	27760321	HT29	viability after 22 days	ACTACGGAGACATCGAGATCGG	IRS2	ENSG00000185950	-0.15587962817737866	[215,168]	[130,289,179]	-1	hSpCas9	negative selection	4994575
109784370	109784392	13	-	27760321	HT29	viability after 22 days	TCCTACCGCCGGGTCTCGGGGG	IRS2	ENSG00000185950	0.2467419260988134	[682,532]	[759,898,844]	2	hSpCas9	negative selection	4994576
109785115	109785137	13	+	27760321	HT29	viability after 22 days	GGCCGACGACCCCGACGATTGG	IRS2	ENSG00000185950	0.41889139678886256	[665,519]	[1097,1002,640]	4	hSpCas9	negative selection	4994577
109785397	109785419	13	+	27760321	HT29	viability after 22 days	CAGACGGTACACCCCCGTCAGG	IRS2	ENSG00000185950	0.37815537647574116	[570,445]	[1073,524,683]	4	hSpCas9	negative selection	4994578
109785781	109785803	13	-	27760321	HT29	viability after 22 days	CAAGGCAGGCGCGCCGAAACGG	IRS2	ENSG00000185950	-0.7431896455859708	[184,144]	[119,85,135]	-6	hSpCas9	negative selection	4994579
109784141	109784163	13	-	27760321	HT29	viability after 19 days	ACTACGGAGACATCGAGATCGG	IRS2	ENSG00000185950	-2.194435513139666	[215,168]	[96,46,6]	-8	hSpCas9	negative selection	5078038
109784370	109784392	13	-	27760321	HT29	viability after 19 days	TCCTACCGCCGGGTCTCGGGGG	IRS2	ENSG00000185950	-0.15618953574168426	[682,532]	[625,680,566]	-1	hSpCas9	negative selection	5078039
109785115	109785137	13	+	27760321	HT29	viability after 19 days	GGCCGACGACCCCGACGATTGG	IRS2	ENSG00000185950	0.5469298820727169	[665,519]	[1034,775,1158]	5	hSpCas9	negative selection	5078040
109785397	109785419	13	+	27760321	HT29	viability after 19 days	CAGACGGTACACCCCCGTCAGG	IRS2	ENSG00000185950	0.2796132696621545	[570,445]	[744,468,899]	2	hSpCas9	negative selection	5078041
109785781	109785803	13	-	27760321	HT29	viability after 19 days	CAAGGCAGGCGCGCCGAAACGG	IRS2	ENSG00000185950	0.4787987781170391	[184,144]	[316,90,381]	5	hSpCas9	negative selection	5078042
109784141	109784163	13	-	27760321	HT29	viability after 16 days	ACTACGGAGACATCGAGATCGG	IRS2	ENSG00000185950	0.4344818314202527	[215,168]	[297,210,366]	5	hSpCas9	negative selection	5161501
109784370	109784392	13	-	27760321	HT29	viability after 16 days	TCCTACCGCCGGGTCTCGGGGG	IRS2	ENSG00000185950	0.053944878401994356	[682,532]	[723,514,885]	0	hSpCas9	negative selection	5161502
109785115	109785137	13	+	27760321	HT29	viability after 16 days	GGCCGACGACCCCGACGATTGG	IRS2	ENSG00000185950	0.4935071424800197	[665,519]	[1161,956,703]	5	hSpCas9	negative selection	5161503
109785397	109785419	13	+	27760321	HT29	viability after 16 days	CAGACGGTACACCCCCGTCAGG	IRS2	ENSG00000185950	0.35186203363171553	[570,445]	[652,849,664]	4	hSpCas9	negative selection	5161504
109785781	109785803	13	-	27760321	HT29	viability after 16 days	CAAGGCAGGCGCGCCGAAACGG	IRS2	ENSG00000185950	-0.7411281012865627	[184,144]	[160,116,57]	-6	hSpCas9	negative selection	5161505
109784141	109784163	13	-	27760321	HT29	viability after 13 days	ACTACGGAGACATCGAGATCGG	IRS2	ENSG00000185950	0.15208305344390471	[215,168]	[437,141,168]	1	hSpCas9	negative selection	5244964
109784370	109784392	13	-	27760321	HT29	viability after 13 days	TCCTACCGCCGGGTCTCGGGGG	IRS2	ENSG00000185950	0.1524121415353571	[682,532]	[875,632,838]	1	hSpCas9	negative selection	5244965
109785115	109785137	13	+	27760321	HT29	viability after 13 days	GGCCGACGACCCCGACGATTGG	IRS2	ENSG00000185950	0.2915845600942142	[665,519]	[901,664,951]	3	hSpCas9	negative selection	5244966
109785397	109785419	13	+	27760321	HT29	viability after 13 days	CAGACGGTACACCCCCGTCAGG	IRS2	ENSG00000185950	-0.08635698254767682	[570,445]	[674,629,372]	-1	hSpCas9	negative selection	5244967
109785781	109785803	13	-	27760321	HT29	viability after 13 days	CAAGGCAGGCGCGCCGAAACGG	IRS2	ENSG00000185950	0.3833975516551429	[184,144]	[271,343,139]	5	hSpCas9	negative selection	5244968
109784141	109784163	13	-	27760321	HT29	viability after 10 days	ACTACGGAGACATCGAGATCGG	IRS2	ENSG00000185950	0.06646052414951253	[215,168]	[136,360,259]	0	hSpCas9	negative selection	5328427
109784370	109784392	13	-	27760321	HT29	viability after 10 days	TCCTACCGCCGGGTCTCGGGGG	IRS2	ENSG00000185950	0.44657559890205956	[682,532]	[981,1089,1032]	6	hSpCas9	negative selection	5328428
109785115	109785137	13	+	27760321	HT29	viability after 10 days	GGCCGACGACCCCGACGATTGG	IRS2	ENSG00000185950	0.46619939044972747	[665,519]	[1022,1034,1010]	6	hSpCas9	negative selection	5328429
109785397	109785419	13	+	27760321	HT29	viability after 10 days	CAGACGGTACACCCCCGTCAGG	IRS2	ENSG00000185950	0.4164813351018668	[570,445]	[1244,787,514]	5	hSpCas9	negative selection	5328430
109785781	109785803	13	-	27760321	HT29	viability after 10 days	CAAGGCAGGCGCGCCGAAACGG	IRS2	ENSG00000185950	-0.22308728530720678	[184,144]	[192,76,254]	-3	hSpCas9	negative selection	5328431
109784141	109784163	13	-	27760321	MOLM13	viability	ACTACGGAGACATCGAGATCGG	IRS2	ENSG00000185950	-1.0673852860701856	[215,215]	[46,67]	-6	hSpCas9	negative selection	5411890
109784370	109784392	13	-	27760321	MOLM13	viability	TCCTACCGCCGGGTCTCGGGGG	IRS2	ENSG00000185950	-0.5998313602218869	[862,682]	[346,233]	-4	hSpCas9	negative selection	5411891
109785115	109785137	13	+	27760321	MOLM13	viability	GGCCGACGACCCCGACGATTGG	IRS2	ENSG00000185950	-0.9515239603829865	[819,665]	[186,239]	-5	hSpCas9	negative selection	5411892
109785397	109785419	13	+	27760321	MOLM13	viability	CAGACGGTACACCCCCGTCAGG	IRS2	ENSG00000185950	-0.5011681107438483	[738,570]	[168,335]	-3	hSpCas9	negative selection	5411893
109785781	109785803	13	-	27760321	MOLM13	viability	CAAGGCAGGCGCGCCGAAACGG	IRS2	ENSG00000185950	0.0789050577561381	[276,184]	[9,242]	0	hSpCas9	negative selection	5411894
109786075	109786098	13	+	27661255	K562	viability	GGCCCGGGCCCGGCGCCCAGGGG	IRS2	ENSG00000185950	-0.369356852326021	[795,873]	[596,445]	-7	dCas9-KRAB	negative selection	5487240
109786529	109786552	13	+	27661255	K562	viability	GCTGCTGCCAACGGCGACCCGGG	IRS2	ENSG00000185950	-0.17036024918009574	[153,129]	[119,84]	-5	dCas9-KRAB	negative selection	5487241
109786137	109786160	13	-	27661255	K562	viability	GGCCGGGCGCAAGGGTGGGAGGG	IRS2	ENSG00000185950	0.02469371337749282	[572,618]	[535,438]	0	dCas9-KRAB	negative selection	5487242
109786141	109786164	13	-	27661255	K562	viability	GGGCGGCCGGGCGCAAGGGTGGG	IRS2	ENSG00000185950	-0.9837536003797034	[229,199]	[92,81]	-8	dCas9-KRAB	negative selection	5487243
109786165	109786188	13	-	27661255	K562	viability	GGCCCGAGGGACGCGTGATCGGG	IRS2	ENSG00000185950	-0.30374422902918186	[238,278]	[198,139]	-7	dCas9-KRAB	negative selection	5487244
109786399	109786422	13	-	27661255	K562	viability	GGCCGCGCGCGCCTTAGGCTCGG	IRS2	ENSG00000185950	-0.05448035395138473	[365,225]	[200,253]	-2	dCas9-KRAB	negative selection	5487245
109786546	109786569	13	-	27661255	K562	viability	GCGGGGACCGCGACGAGCCCGGG	IRS2	ENSG00000185950	-0.33344785564606133	[543,625]	[424,322]	-7	dCas9-KRAB	negative selection	5487246
109786568	109786591	13	-	27661255	K562	viability	GCGATGTGTTACTCACTGTGCGG	IRS2	ENSG00000185950	-0.016988253043361323	[843,849]	[795,559]	0	dCas9-KRAB	negative selection	5487247
109785682	109785705	13	+	27260156	BXPC3	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.13331572360994048	[638]	[580,544,539,794]	-3	hSpCas9	negative selection	5549761
109785767	109785790	13	+	27260156	BXPC3	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.375733774164837	[1280]	[1055,834,1013,1252]	-7	hSpCas9	negative selection	5549762
109783442	109783465	13	+	27260156	BXPC3	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.05149692015024687	[407]	[406,429,455,481]	1	hSpCas9	negative selection	5549763
109782733	109782756	13	-	27260156	BXPC3	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.4035521508487149	[321]	[203,255,247,321]	-7	hSpCas9	negative selection	5614017
109785899	109785922	13	-	27260156	BXPC3	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.07410048298836647	[135]	[138,134,128,202]	1	hSpCas9	negative selection	5614018
109782630	109782653	13	-	27260156	BXPC3	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.4182436576830446	[141]	[195,230,179,180]	8	hSpCas9	negative selection	5614019
109785682	109785705	13	+	27260156	A673	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.2833638992022973	[638]	[564,724,660,554]	-6	hSpCas9	negative selection	5671012
109785767	109785790	13	+	27260156	A673	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.49361096304595486	[1280]	[1343,892,1087,1075]	-8	hSpCas9	negative selection	5671013
109783442	109783465	13	+	27260156	A673	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.03307577913443191	[407]	[550,469,412,489]	-1	hSpCas9	negative selection	5671014
109782733	109782756	13	-	27260156	A673	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.4135684698421146	[321]	[264,291,256,346]	-7	hSpCas9	negative selection	5735268
109785899	109785922	13	-	27260156	A673	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.29516649573239917	[135]	[218,227,168,185]	7	hSpCas9	negative selection	5735269
109782630	109782653	13	-	27260156	A673	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.23217567659980975	[141]	[209,215,169,205]	5	hSpCas9	negative selection	5735270
109785682	109785705	13	+	27260156	A375	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.7257937894831157	[638]	[411,528,597,293]	-7	hSpCas9	negative selection	5792263
109785767	109785790	13	+	27260156	A375	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-1.4386451379162184	[1280]	[499,631,555,530]	-9	hSpCas9	negative selection	5792264
109783442	109783465	13	+	27260156	A375	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.3941161108277652	[407]	[342,443,335,339]	-5	hSpCas9	negative selection	5792265
109782733	109782756	13	-	27260156	A375	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.8521713351074025	[321]	[292,210,217,121]	-8	hSpCas9	negative selection	5856519
109785899	109785922	13	-	27260156	A375	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.31521662285608754	[135]	[174,128,323,156]	4	hSpCas9	negative selection	5856520
109782630	109782653	13	-	27260156	A375	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.1070524094466554	[141]	[169,274,175,113]	1	hSpCas9	negative selection	5856521
109785682	109785705	13	+	27260156	COLO741	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.4635939152267937	[638]	[607,614,555]	-7	hSpCas9	negative selection	5913514
109785767	109785790	13	+	27260156	COLO741	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.4329016648382147	[1280]	[1298,1202,1144]	-7	hSpCas9	negative selection	5913515
109783442	109783465	13	+	27260156	COLO741	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.3937717292150251	[407]	[385,369,429]	-7	hSpCas9	negative selection	5913516
109782733	109782756	13	-	27260156	COLO741	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.24805804851452518	[321]	[361,375,304]	-5	hSpCas9	negative selection	5977770
109785899	109785922	13	-	27260156	COLO741	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	-0.3854252376315064	[135]	[117,124,152]	-7	hSpCas9	negative selection	5977771
109782630	109782653	13	-	27260156	COLO741	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	-0.27846256827600047	[141]	[126,203,117]	-5	hSpCas9	negative selection	5977772
109785682	109785705	13	+	27260156	CAL120	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.5045743523284825	[638]	[560,542,576]	-6	hSpCas9	negative selection	6034765
109785767	109785790	13	+	27260156	CAL120	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.32418619961285855	[1280]	[1641,1310,927]	-5	hSpCas9	negative selection	6034766
109783442	109783465	13	+	27260156	CAL120	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.7824667223379415	[407]	[248,253,373]	-8	hSpCas9	negative selection	6034767
109782733	109782756	13	-	27260156	CAL120	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-1.0947240840875594	[321]	[238,171,159]	-8	hSpCas9	negative selection	6099021
109785899	109785922	13	-	27260156	CAL120	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.4839261102275647	[135]	[196,326,180]	7	hSpCas9	negative selection	6099022
109782630	109782653	13	-	27260156	CAL120	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.6186869302651463	[141]	[373,110,342]	8	hSpCas9	negative selection	6099023
109785682	109785705	13	+	27260156	CADOES1	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.37971124644387483	[638]	[514,454,526,324]	-6	hSpCas9	negative selection	6156016
109785767	109785790	13	+	27260156	CADOES1	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.5557893426114638	[1280]	[735,668,868,973]	-7	hSpCas9	negative selection	6156017
109783442	109783465	13	+	27260156	CADOES1	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.03147079919047002	[407]	[434,256,468,389]	0	hSpCas9	negative selection	6156018
109782733	109782756	13	-	27260156	CADOES1	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-1.0690520814727258	[321]	[136,123,190,117]	-9	hSpCas9	negative selection	6220272
109785899	109785922	13	-	27260156	CADOES1	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.325820462642862	[135]	[178,113,105,237]	5	hSpCas9	negative selection	6220273
109782630	109782653	13	-	27260156	CADOES1	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.5131565696627891	[141]	[82,190,219,262]	8	hSpCas9	negative selection	6220274
109785682	109785705	13	+	27260156	EWS502	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.1743393367116685	[638]	[643,592,554,598]	-3	hSpCas9	negative selection	6277267
109785767	109785790	13	+	27260156	EWS502	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.39781247739675374	[1280]	[926,1061,1133,1002]	-6	hSpCas9	negative selection	6277268
109783442	109783465	13	+	27260156	EWS502	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.06335731974907705	[407]	[377,497,482,452]	1	hSpCas9	negative selection	6277269
109782733	109782756	13	-	27260156	EWS502	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.08860069936480974	[321]	[292,210,411,378]	-2	hSpCas9	negative selection	6341523
109785899	109785922	13	-	27260156	EWS502	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	-0.17114795325488386	[135]	[94,149,133,135]	-3	hSpCas9	negative selection	6341524
109782630	109782653	13	-	27260156	EWS502	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.5391356430372671	[141]	[222,259,207,176]	8	hSpCas9	negative selection	6341525
109785682	109785705	13	+	27260156	EW8	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.6314894607719387	[638]	[398,355,235,368]	-8	hSpCas9	negative selection	6398518
109785767	109785790	13	+	27260156	EW8	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.7459281140712716	[1280]	[628,627,627,588]	-8	hSpCas9	negative selection	6398519
109783442	109783465	13	+	27260156	EW8	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.10078462487356796	[407]	[349,258,366,250]	-2	hSpCas9	negative selection	6398520
109782733	109782756	13	-	27260156	EW8	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.338899707934076	[321]	[284,233,204,109]	-6	hSpCas9	negative selection	6462774
109785899	109785922	13	-	27260156	EW8	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.3263836306498953	[135]	[275,119,70,111]	6	hSpCas9	negative selection	6462775
109782630	109782653	13	-	27260156	EW8	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.33751047716758253	[141]	[173,121,134,154]	6	hSpCas9	negative selection	6462776
109785682	109785705	13	+	27260156	CORL105	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	0.01276500233502903	[638]	[798,677,807,744]	0	hSpCas9	negative selection	6519769
109785767	109785790	13	+	27260156	CORL105	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.1688385415811653	[1280]	[1269,1241,1542,1312]	-3	hSpCas9	negative selection	6519770
109783442	109783465	13	+	27260156	CORL105	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.09861146034832632	[407]	[524,346,578,358]	-2	hSpCas9	negative selection	6519771
109782733	109782756	13	-	27260156	CORL105	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.17266917536774506	[321]	[272,305,329,425]	-3	hSpCas9	negative selection	6584025
109785899	109785922	13	-	27260156	CORL105	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.07547230864315968	[135]	[125,127,223,200]	1	hSpCas9	negative selection	6584026
109782630	109782653	13	-	27260156	CORL105	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.20214800207115324	[141]	[186,222,245,116]	4	hSpCas9	negative selection	6584027
109785682	109785705	13	+	27260156	HS294T	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.22179038939159906	[638]	[207,181,211,252]	-3	hSpCas9	negative selection	6641020
109785767	109785790	13	+	27260156	HS294T	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.28861402003816683	[1280]	[291,340,354,693]	-4	hSpCas9	negative selection	6641021
109783442	109783465	13	+	27260156	HS294T	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.3672083004420237	[407]	[52,83,116,266]	-5	hSpCas9	negative selection	6641022
109782733	109782756	13	-	27260156	HS294T	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.3738484059884648	[321]	[84,68,105,131]	-5	hSpCas9	negative selection	6705276
109785899	109785922	13	-	27260156	HS294T	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.6533786880644152	[135]	[136,47,35,109]	8	hSpCas9	negative selection	6705277
109782630	109782653	13	-	27260156	HS294T	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.3463471191844374	[141]	[47,63,40,139]	4	hSpCas9	negative selection	6705278
109785682	109785705	13	+	27260156	HCC44	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.3442886660715172	[638]	[567,315,718,725]	-5	hSpCas9	negative selection	6762271
109785767	109785790	13	+	27260156	HCC44	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.5154282144441383	[1280]	[1452,543,1259,940]	-6	hSpCas9	negative selection	6762272
109783442	109783465	13	+	27260156	HCC44	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.2281440838241395	[407]	[474,263,377,475]	-4	hSpCas9	negative selection	6762273
109782733	109782756	13	-	27260156	HCC44	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.6588278085311003	[321]	[131,138,327,338]	-7	hSpCas9	negative selection	6826527
109785899	109785922	13	-	27260156	HCC44	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.4090469074582195	[135]	[294,152,280,117]	6	hSpCas9	negative selection	6826528
109782630	109782653	13	-	27260156	HCC44	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.03322035874042828	[141]	[339,126,97,102]	0	hSpCas9	negative selection	6826529
109785682	109785705	13	+	27260156	G402	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	0.08109525876331158	[638]	[842,1057,879,544]	1	hSpCas9	negative selection	6883522
109785767	109785790	13	+	27260156	G402	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	0.0378035761895843	[1280]	[1975,1738,1587,1190]	0	hSpCas9	negative selection	6883523
109783442	109783465	13	+	27260156	G402	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.32939745831393186	[407]	[577,644,518,745]	4	hSpCas9	negative selection	6883524
109782733	109782756	13	-	27260156	G402	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.1089707469500254	[321]	[300,399,408,339]	-1	hSpCas9	negative selection	6947778
109785899	109785922	13	-	27260156	G402	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	1.2764100789565718	[135]	[349,574,431,258]	9	hSpCas9	negative selection	6947779
109782630	109782653	13	-	27260156	G402	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.9683264248103367	[141]	[166,346,596,224]	9	hSpCas9	negative selection	6947780
109785682	109785705	13	+	27260156	L33	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.37239972066513494	[638]	[516,196,323,460]	-7	hSpCas9	negative selection	7004773
109785767	109785790	13	+	27260156	L33	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.012446153521822101	[1280]	[1124,573,881,1155]	0	hSpCas9	negative selection	7004774
109783442	109783465	13	+	27260156	L33	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.1828737442359624	[407]	[406,129,228,347]	-4	hSpCas9	negative selection	7004775
109782733	109782756	13	-	27260156	L33	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.0883155440340474	[321]	[288,173,129,290]	-2	hSpCas9	negative selection	7069029
109785899	109785922	13	-	27260156	L33	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	-0.08456960206048625	[135]	[97,68,74,127]	-2	hSpCas9	negative selection	7069030
109782630	109782653	13	-	27260156	L33	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.01624650516798276	[141]	[154,51,96,137]	0	hSpCas9	negative selection	7069031
109785682	109785705	13	+	27260156	K562	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	0.07431330073765152	[638]	[949,706,389,396]	0	hSpCas9	negative selection	7126024
109785767	109785790	13	+	27260156	K562	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	0.14889630318297042	[1280]	[899,1353,1255,1475]	1	hSpCas9	negative selection	7126025
109783442	109783465	13	+	27260156	K562	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.7201954410971843	[407]	[447,216,841,817]	8	hSpCas9	negative selection	7126026
109782733	109782756	13	-	27260156	K562	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	0.2540998072828647	[321]	[314,273,519,256]	3	hSpCas9	negative selection	7190280
109785899	109785922	13	-	27260156	K562	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.048932923587321264	[135]	[216,81,172,41]	0	hSpCas9	negative selection	7190281
109782630	109782653	13	-	27260156	K562	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.47739862450686377	[141]	[199,109,151,230]	6	hSpCas9	negative selection	7190282
109785682	109785705	13	+	27260156	HT29	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.40924160428614526	[638]	[735,739,412,483]	-6	hSpCas9	negative selection	7247275
109785767	109785790	13	+	27260156	HT29	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.3302891633665095	[1280]	[1484,1282,1257,974]	-6	hSpCas9	negative selection	7247276
109783442	109783465	13	+	27260156	HT29	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.12230229418802768	[407]	[552,494,639,472]	2	hSpCas9	negative selection	7247277
109782733	109782756	13	-	27260156	HT29	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.2953765084788875	[321]	[193,297,503,271]	-5	hSpCas9	negative selection	7311531
109785899	109785922	13	-	27260156	HT29	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.2674995724326117	[135]	[292,174,206,132]	5	hSpCas9	negative selection	7311532
109782630	109782653	13	-	27260156	HT29	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.2762422366268369	[141]	[187,238,229,181]	5	hSpCas9	negative selection	7311533
109785682	109785705	13	+	27260156	MHHES1	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.21103590810488218	[638]	[600,837,522,546]	-4	hSpCas9	negative selection	7368526
109785767	109785790	13	+	27260156	MHHES1	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.04644505373327146	[1280]	[1562,1253,1408,1346]	-1	hSpCas9	negative selection	7368527
109783442	109783465	13	+	27260156	MHHES1	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.09062444303864403	[407]	[478,402,512,530]	1	hSpCas9	negative selection	7368528
109782733	109782756	13	-	27260156	MHHES1	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.23205597495880537	[321]	[429,202,240,347]	-4	hSpCas9	negative selection	7432782
109785899	109785922	13	-	27260156	MHHES1	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.45317235722574933	[135]	[193,266,234,154]	7	hSpCas9	negative selection	7432783
109782630	109782653	13	-	27260156	MHHES1	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.556463188422363	[141]	[195,229,378,146]	8	hSpCas9	negative selection	7432784
109785682	109785705	13	+	27260156	MEWO	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.4792099153251683	[638]	[486,377,432]	-8	hSpCas9	negative selection	7489777
109785767	109785790	13	+	27260156	MEWO	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.19443896047231313	[1280]	[1183,898,1085]	-4	hSpCas9	negative selection	7489778
109783442	109783465	13	+	27260156	MEWO	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.06705901634917641	[407]	[420,365,316]	-1	hSpCas9	negative selection	7489779
109782733	109782756	13	-	27260156	MEWO	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.45156971526672507	[321]	[185,255,211]	-7	hSpCas9	negative selection	7554033
109785899	109785922	13	-	27260156	MEWO	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.08164022960923023	[135]	[165,129,113]	1	hSpCas9	negative selection	7554034
109782630	109782653	13	-	27260156	MEWO	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	-0.8503676538722342	[141]	[93,67,62]	-9	hSpCas9	negative selection	7554035
109785682	109785705	13	+	27260156	LNCAPCLONEFGC	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.15862235999002505	[638]	[560,484,576,460]	-3	hSpCas9	negative selection	7611028
109785767	109785790	13	+	27260156	LNCAPCLONEFGC	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	0.2696359157230128	[1280]	[1523,1135,1543,1426]	4	hSpCas9	negative selection	7611029
109783442	109783465	13	+	27260156	LNCAPCLONEFGC	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.07474685131041939	[407]	[376,312,449,430]	1	hSpCas9	negative selection	7611030
109782733	109782756	13	-	27260156	LNCAPCLONEFGC	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.176587571911605	[321]	[253,255,167,340]	-3	hSpCas9	negative selection	7675284
109785899	109785922	13	-	27260156	LNCAPCLONEFGC	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.27699598007690596	[135]	[161,127,154,153]	4	hSpCas9	negative selection	7675285
109782630	109782653	13	-	27260156	LNCAPCLONEFGC	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.3898229530440449	[141]	[250,134,116,163]	6	hSpCas9	negative selection	7675286
109785682	109785705	13	+	27260156	PANC0327	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.5074003632570137	[638]	[623,227,521,263]	-6	hSpCas9	negative selection	7732279
109785767	109785790	13	+	27260156	PANC0327	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.6990895759681305	[1280]	[974,682,534,634]	-7	hSpCas9	negative selection	7732280
109783442	109783465	13	+	27260156	PANC0327	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.23790746027899318	[407]	[430,240,546,514]	3	hSpCas9	negative selection	7732281
109782733	109782756	13	-	27260156	PANC0327	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.9776791578366337	[321]	[192,120,143,129]	-8	hSpCas9	negative selection	7796535
109785899	109785922	13	-	27260156	PANC0327	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	-0.16580951348601447	[135]	[48,90,92,194]	-2	hSpCas9	negative selection	7796536
109782630	109782653	13	-	27260156	PANC0327	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	-0.10574333853397522	[141]	[166,185,53,56]	-1	hSpCas9	negative selection	7796537
109785682	109785705	13	+	27260156	NCIH2009	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-1.1415049249627036	[638]	[417,459,336]	-8	hSpCas9	negative selection	7853530
109785767	109785790	13	+	27260156	NCIH2009	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-1.0895093945168017	[1280]	[1067,706,793]	-8	hSpCas9	negative selection	7853531
109783442	109783465	13	+	27260156	NCIH2009	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.6970128691783744	[407]	[408,275,381]	-7	hSpCas9	negative selection	7853532
109782733	109782756	13	-	27260156	NCIH2009	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-1.7868560796181148	[321]	[109,123,152]	-9	hSpCas9	negative selection	7917786
109785899	109785922	13	-	27260156	NCIH2009	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	-0.054395184368215554	[135]	[222,157,175]	0	hSpCas9	negative selection	7917787
109782630	109782653	13	-	27260156	NCIH2009	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.160906217306219	[141]	[213,193,255]	2	hSpCas9	negative selection	7917788
109785682	109785705	13	+	27260156	NCIH1373	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	0.2121524243848384	[638]	[1245,505,1210,109]	2	hSpCas9	negative selection	7974781
109785767	109785790	13	+	27260156	NCIH1373	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.07398045864445901	[1280]	[1668,1113,1510,319]	0	hSpCas9	negative selection	7974782
109783442	109783465	13	+	27260156	NCIH1373	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.0794447542158789	[407]	[430,413,531,90]	-1	hSpCas9	negative selection	7974783
109782733	109782756	13	-	27260156	NCIH1373	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	0.12233415225874822	[321]	[250,179,487,174]	1	hSpCas9	negative selection	8039037
109785899	109785922	13	-	27260156	NCIH1373	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.4691122244870469	[135]	[423,123,185,38]	4	hSpCas9	negative selection	8039038
109782630	109782653	13	-	27260156	NCIH1373	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	-0.7527800884384794	[141]	[174,44,76,25]	-6	hSpCas9	negative selection	8039039
109785682	109785705	13	+	27260156	PATU8902	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.7487482741928597	[638]	[564,339,715,431]	-6	hSpCas9	negative selection	8096032
109785767	109785790	13	+	27260156	PATU8902	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-1.4012759050826777	[1280]	[778,573,434,1008]	-8	hSpCas9	negative selection	8096033
109783442	109783465	13	+	27260156	PATU8902	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-1.1928369816983526	[407]	[271,127,434,88]	-8	hSpCas9	negative selection	8096034
109782733	109782756	13	-	27260156	PATU8902	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.8967348062763285	[321]	[139,334,168,350]	-7	hSpCas9	negative selection	8160288
109785899	109785922	13	-	27260156	PATU8902	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	-0.2374898454340919	[135]	[211,162,197,43]	-2	hSpCas9	negative selection	8160289
109782630	109782653	13	-	27260156	PATU8902	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.10327043692892524	[141]	[110,155,236,355]	1	hSpCas9	negative selection	8160290
109785682	109785705	13	+	27260156	PANC1	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.13747237424080483	[638]	[469,686,477,406]	-2	hSpCas9	negative selection	8217283
109785767	109785790	13	+	27260156	PANC1	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.378972239352777	[1280]	[833,980,807,784]	-5	hSpCas9	negative selection	8217284
109783442	109783465	13	+	27260156	PANC1	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.10622991986732558	[407]	[207,317,408,357]	-2	hSpCas9	negative selection	8217285
109782733	109782756	13	-	27260156	PANC1	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.26269855619325777	[321]	[185,322,330,117]	-4	hSpCas9	negative selection	8281539
109785899	109785922	13	-	27260156	PANC1	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	-0.05634883094693133	[135]	[116,193,115,47]	-1	hSpCas9	negative selection	8281540
109782630	109782653	13	-	27260156	PANC1	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.007244590854863064	[141]	[87,130,109,155]	0	hSpCas9	negative selection	8281541
109785682	109785705	13	+	27260156	PANC0813	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.8388356464064926	[638]	[476,368,361,471]	-8	hSpCas9	negative selection	8338534
109785767	109785790	13	+	27260156	PANC0813	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.2539154346693915	[1280]	[1586,1037,1303,1152]	-4	hSpCas9	negative selection	8338535
109783442	109783465	13	+	27260156	PANC0813	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.21334668681298366	[407]	[436,357,477,383]	-3	hSpCas9	negative selection	8338536
109782733	109782756	13	-	27260156	PANC0813	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.31283748622524776	[321]	[363,238,416,208]	-5	hSpCas9	negative selection	8402790
109785899	109785922	13	-	27260156	PANC0813	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	-0.23582421614555815	[135]	[152,134,206,53]	-4	hSpCas9	negative selection	8402791
109782630	109782653	13	-	27260156	PANC0813	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.12085382274048828	[141]	[161,219,240,104]	2	hSpCas9	negative selection	8402792
109785682	109785705	13	+	27260156	RDES	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-1.1355912665092278	[638]	[295,244,297,534]	-9	hSpCas9	negative selection	8459785
109785767	109785790	13	+	27260156	RDES	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-1.2192383477978073	[1280]	[518,679,574,776]	-9	hSpCas9	negative selection	8459786
109783442	109783465	13	+	27260156	RDES	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.27113141412719977	[407]	[332,371,440,416]	-4	hSpCas9	negative selection	8459787
109782733	109782756	13	-	27260156	RDES	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-1.2858847799365793	[321]	[135,106,174,200]	-9	hSpCas9	negative selection	8524041
109785899	109785922	13	-	27260156	RDES	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.014232444210975803	[135]	[142,160,137,191]	0	hSpCas9	negative selection	8524042
109782630	109782653	13	-	27260156	RDES	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.32752474357771	[141]	[210,172,263,161]	5	hSpCas9	negative selection	8524043
109785682	109785705	13	+	27260156	PC3	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.21518977431400332	[638]	[356,578,902,518]	-5	hSpCas9	negative selection	8581036
109785767	109785790	13	+	27260156	PC3	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.0851774838565289	[1280]	[690,1226,1623,1565]	-2	hSpCas9	negative selection	8581037
109783442	109783465	13	+	27260156	PC3	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.1216809180602699	[407]	[345,416,748,364]	2	hSpCas9	negative selection	8581038
109782733	109782756	13	-	27260156	PC3	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	0.28319730086800554	[321]	[227,279,860,420]	6	hSpCas9	negative selection	8645292
109785899	109785922	13	-	27260156	PC3	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.2007584588393767	[135]	[97,102,157,283]	4	hSpCas9	negative selection	8645293
109782630	109782653	13	-	27260156	PC3	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.48938701221555503	[141]	[145,140,241,290]	8	hSpCas9	negative selection	8645294
109785682	109785705	13	+	27260156	PATU8988T	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.16441746023795678	[638]	[464,611,463,679]	-3	hSpCas9	negative selection	8702287
109785767	109785790	13	+	27260156	PATU8988T	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.6645046221456151	[1280]	[913,640,790,762]	-8	hSpCas9	negative selection	8702288
109783442	109783465	13	+	27260156	PATU8988T	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.035463456672367166	[407]	[431,484,324,380]	0	hSpCas9	negative selection	8702289
109782733	109782756	13	-	27260156	PATU8988T	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.16216481394549642	[321]	[325,184,274,320]	-3	hSpCas9	negative selection	8766543
109785899	109785922	13	-	27260156	PATU8988T	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.2774229992840638	[135]	[81,335,84,150]	5	hSpCas9	negative selection	8766544
109782630	109782653	13	-	27260156	PATU8988T	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	-0.3776543865827	[141]	[105,201,44,76]	-6	hSpCas9	negative selection	8766545
109785682	109785705	13	+	27260156	T47D	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.0825595198111796	[638]	[759,656,679,719]	-2	hSpCas9	negative selection	8823538
109785767	109785790	13	+	27260156	T47D	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.004231044115123428	[1280]	[1605,1256,1536,1573]	0	hSpCas9	negative selection	8823539
109783442	109783465	13	+	27260156	T47D	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.09615988516340723	[407]	[540,498,513,477]	2	hSpCas9	negative selection	8823540
109782733	109782756	13	-	27260156	T47D	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.04121166798554332	[321]	[433,341,321,362]	-1	hSpCas9	negative selection	8887794
109785899	109785922	13	-	27260156	T47D	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.31062378131636303	[135]	[234,146,194,213]	6	hSpCas9	negative selection	8887795
109782630	109782653	13	-	27260156	T47D	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.48768881538011155	[141]	[221,215,211,280]	8	hSpCas9	negative selection	8887796
109785682	109785705	13	+	27260156	SU8686	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.19365226097505583	[638]	[576,446,507,715]	-3	hSpCas9	negative selection	8944789
109785767	109785790	13	+	27260156	SU8686	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.015628404903835325	[1280]	[1230,1123,1173,1552]	0	hSpCas9	negative selection	8944790
109783442	109783465	13	+	27260156	SU8686	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.14710273655867093	[407]	[350,411,480,582]	2	hSpCas9	negative selection	8944791
109782733	109782756	13	-	27260156	SU8686	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.1809915642611163	[321]	[278,264,228,365]	-3	hSpCas9	negative selection	9009045
109785899	109785922	13	-	27260156	SU8686	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.2517996293655045	[135]	[117,105,215,224]	4	hSpCas9	negative selection	9009046
109782630	109782653	13	-	27260156	SU8686	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.30504908301076106	[141]	[115,217,191,168]	5	hSpCas9	negative selection	9009047
109785682	109785705	13	+	27260156	SKES1	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.5773205395152544	[638]	[326,723,442,252]	-8	hSpCas9	negative selection	9066040
109785767	109785790	13	+	27260156	SKES1	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.595631707920922	[1280]	[1071,832,801,712]	-8	hSpCas9	negative selection	9066041
109783442	109783465	13	+	27260156	SKES1	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.40105013270462675	[407]	[335,271,374,251]	-7	hSpCas9	negative selection	9066042
109782733	109782756	13	-	27260156	SKES1	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-1.1671702792438727	[321]	[126,172,168,106]	-9	hSpCas9	negative selection	9130296
109785899	109785922	13	-	27260156	SKES1	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.04725766003284915	[135]	[152,154,71,178]	1	hSpCas9	negative selection	9130297
109782630	109782653	13	-	27260156	SKES1	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.07582457693765376	[141]	[200,163,118,123]	1	hSpCas9	negative selection	9130298
109785682	109785705	13	+	27260156	TOV112D	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.15265214502256957	[638]	[640,550,555,553]	-3	hSpCas9	negative selection	9187291
109785767	109785790	13	+	27260156	TOV112D	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	0.24210427758296293	[1280]	[2054,1472,1401,1180]	4	hSpCas9	negative selection	9187292
109783442	109783465	13	+	27260156	TOV112D	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.3175686265444697	[407]	[322,418,333,258]	-6	hSpCas9	negative selection	9187293
109782733	109782756	13	-	27260156	TOV112D	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	0.1103894935331925	[321]	[438,421,359,200]	2	hSpCas9	negative selection	9251547
109785899	109785922	13	-	27260156	TOV112D	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.15204983455466747	[135]	[132,255,75,163]	3	hSpCas9	negative selection	9251548
109782630	109782653	13	-	27260156	TOV112D	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.020273262260153135	[141]	[124,113,233,95]	0	hSpCas9	negative selection	9251549
109785682	109785705	13	+	27260156	TC71	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.7042345290253671	[638]	[431,507,368,370]	-9	hSpCas9	negative selection	9308542
109785767	109785790	13	+	27260156	TC71	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.7286836629627771	[1280]	[788,754,836,940]	-9	hSpCas9	negative selection	9308543
109783442	109783465	13	+	27260156	TC71	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	-0.3567001626037972	[407]	[316,332,300,421]	-7	hSpCas9	negative selection	9308544
109782733	109782756	13	-	27260156	TC71	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.5177027455939409	[321]	[194,255,235,280]	-8	hSpCas9	negative selection	9372798
109785899	109785922	13	-	27260156	TC71	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	-0.20331173984098916	[135]	[108,86,142,169]	-5	hSpCas9	negative selection	9372799
109782630	109782653	13	-	27260156	TC71	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	-0.16435384608970582	[141]	[91,202,113,135]	-4	hSpCas9	negative selection	9372800
109785682	109785705	13	+	27260156	TC32	viability	CACGGCGAAGTACTCGTCCTTGG	IRS2	ENSG00000185950	-0.5690734609190367	[638]	[346,282,462,575]	-8	hSpCas9	negative selection	9429793
109785767	109785790	13	+	27260156	TC32	viability	TCGAGAGCGATCACCCGTTTCGG	IRS2	ENSG00000185950	-0.5884138242791553	[1280]	[805,629,955,854]	-8	hSpCas9	negative selection	9429794
109783442	109783465	13	+	27260156	TC32	viability	CGCACGGGCGAAGGCACTACAGG	IRS2	ENSG00000185950	0.18972168962306482	[407]	[317,322,758,438]	3	hSpCas9	negative selection	9429795
109782733	109782756	13	-	27260156	TC32	viability	GCCCGACGTCGGGCGTGAAGAGG	IRS2	ENSG00000185950	-0.6134600439342905	[321]	[134,188,225,247]	-8	hSpCas9	negative selection	9494049
109785899	109785922	13	-	27260156	TC32	viability	AAGCGCTTCTTCGTGCTGCGCGG	IRS2	ENSG00000185950	0.4999652139627224	[135]	[133,179,186,219]	8	hSpCas9	negative selection	9494050
109782630	109782653	13	-	27260156	TC32	viability	GGTCATCCGCGCAGACCCGCAGG	IRS2	ENSG00000185950	0.06272649864056024	[141]	[77,93,198,218]	1	hSpCas9	negative selection	9494051
109784184	109784207	13	+	27869803	HPAFII	viability after 27 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	0.6992739936174561	[199]	[155,182,NaN]	5	hSpCas9	negative selection	9549159
109784380	109784403	13	-	27869803	HPAFII	viability after 27 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	0.1062413028823983	[310]	[241,120,NaN]	0	hSpCas9	negative selection	9549160
109785372	109785395	13	+	27869803	HPAFII	viability after 27 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.30067198530081785	[413]	[356,193,NaN]	2	hSpCas9	negative selection	9549161
109785624	109785647	13	+	27869803	HPAFII	viability after 27 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	0.248248003057149	[457]	[285,285,NaN]	2	hSpCas9	negative selection	9549162
109785657	109785680	13	-	27869803	HPAFII	viability after 27 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-0.7217012234914255	[220]	[70,69,NaN]	-5	hSpCas9	negative selection	9549163
109785893	109785916	13	-	27869803	HPAFII	viability after 27 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	0.2600277388710433	[240]	[160,143,NaN]	2	hSpCas9	negative selection	9549164
109784184	109784207	13	+	27869803	HPAFII	viability after 15 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	0.0945087633882741	[199]	[210,240,NaN]	1	hSpCas9	negative selection	9631608
109784380	109784403	13	-	27869803	HPAFII	viability after 15 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	0.2328294917492995	[310]	[697,202,NaN]	2	hSpCas9	negative selection	9631609
109785372	109785395	13	+	27869803	HPAFII	viability after 15 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.13037429307402393	[413]	[864,251,NaN]	1	hSpCas9	negative selection	9631610
109785624	109785647	13	+	27869803	HPAFII	viability after 15 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	0.3548561516368516	[457]	[499,709,NaN]	4	hSpCas9	negative selection	9631611
109785657	109785680	13	-	27869803	HPAFII	viability after 15 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-0.6819757617891684	[220]	[279,65,NaN]	-6	hSpCas9	negative selection	9631612
109785893	109785916	13	-	27869803	HPAFII	viability after 15 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-0.2819984395763996	[240]	[278,171,NaN]	-3	hSpCas9	negative selection	9631613
109784184	109784207	13	+	27869803	ASPC1	viability after 36 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-2.980729094736062	[541]	[40,0,29]	-9	hSpCas9	negative selection	9714057
109784380	109784403	13	-	27869803	ASPC1	viability after 36 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-0.5706193546562608	[813]	[182,91,273]	-5	hSpCas9	negative selection	9714058
109785372	109785395	13	+	27869803	ASPC1	viability after 36 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.6703065006788688	[1038]	[259,611,765]	6	hSpCas9	negative selection	9714059
109785624	109785647	13	+	27869803	ASPC1	viability after 36 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-1.9676595484818955	[1509]	[157,125,123]	-9	hSpCas9	negative selection	9714060
109785657	109785680	13	-	27869803	ASPC1	viability after 36 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-2.2728213314628136	[605]	[71,22,39]	-9	hSpCas9	negative selection	9714061
109785893	109785916	13	-	27869803	ASPC1	viability after 36 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-1.2052926661981698	[476]	[23,64,110]	-8	hSpCas9	negative selection	9714062
109784184	109784207	13	+	27869803	PATU8988S	viability after 35 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-1.3715317601642132	[468]	[73,71,NaN]	-8	hSpCas9	negative selection	9796506
109784380	109784403	13	-	27869803	PATU8988S	viability after 35 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-0.642085885932335	[503]	[160,98,NaN]	-6	hSpCas9	negative selection	9796507
109785372	109785395	13	+	27869803	PATU8988S	viability after 35 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.0033476258254079294	[884]	[471,241,NaN]	0	hSpCas9	negative selection	9796508
109785624	109785647	13	+	27869803	PATU8988S	viability after 35 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-2.678194891668622	[1344]	[142,25,NaN]	-9	hSpCas9	negative selection	9796509
109785657	109785680	13	-	27869803	PATU8988S	viability after 35 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-3.504074340216038	[549]	[29,8,NaN]	-9	hSpCas9	negative selection	9796510
109785893	109785916	13	-	27869803	PATU8988S	viability after 35 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-1.0439090690186241	[555]	[155,60,NaN]	-7	hSpCas9	negative selection	9796511
109784184	109784207	13	+	27869803	PATU8988S	viability after 31 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	-0.31972936608103364	[468]	[133,169,NaN]	-4	hSpCas9	negative selection	9878955
109784380	109784403	13	-	27869803	PATU8988S	viability after 31 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	-1.229234468548611	[503]	[90,78,NaN]	-8	hSpCas9	negative selection	9878956
109785372	109785395	13	+	27869803	PATU8988S	viability after 31 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	-0.04129738510402958	[884]	[389,282,NaN]	0	hSpCas9	negative selection	9878957
109785624	109785647	13	+	27869803	PATU8988S	viability after 31 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-1.7904190042033619	[1344]	[158,149,NaN]	-9	hSpCas9	negative selection	9878958
109785657	109785680	13	-	27869803	PATU8988S	viability after 31 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-2.83385403535031	[549]	[28,32,NaN]	-9	hSpCas9	negative selection	9878959
109785893	109785916	13	-	27869803	PATU8988S	viability after 31 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	-1.1422524900885513	[555]	[110,86,NaN]	-8	hSpCas9	negative selection	9878960
109784184	109784207	13	+	27869803	HPAFII	viability after 35 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	0.3575264069287153	[199]	[45,223,NaN]	2	hSpCas9	negative selection	9961404
109784380	109784403	13	-	27869803	HPAFII	viability after 35 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	0.3973093959928368	[310]	[220,191,NaN]	2	hSpCas9	negative selection	9961405
109785372	109785395	13	+	27869803	HPAFII	viability after 35 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.33001185641698194	[413]	[349,165,NaN]	2	hSpCas9	negative selection	9961406
109785624	109785647	13	+	27869803	HPAFII	viability after 35 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-0.12304827652140216	[457]	[139,294,NaN]	0	hSpCas9	negative selection	9961407
109785657	109785680	13	-	27869803	HPAFII	viability after 35 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-1.5399905218105643	[220]	[45,29,NaN]	-7	hSpCas9	negative selection	9961408
109785893	109785916	13	-	27869803	HPAFII	viability after 35 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	0.5508471094434247	[240]	[110,254,NaN]	3	hSpCas9	negative selection	9961409
109784184	109784207	13	+	27869803	HPAFII	viability after 31 days	CCACCTTGGGAGAGGACGCGGGG	IRS2	ENSG00000185950	0.9372284791762658	[199]	[56,386,NaN]	7	hSpCas9	negative selection	10043853
109784380	109784403	13	-	27869803	HPAFII	viability after 31 days	ACTGTGGCCGCTCCTACCGCCGG	IRS2	ENSG00000185950	0.04942568079717469	[310]	[227,128,NaN]	0	hSpCas9	negative selection	10043854
109785372	109785395	13	+	27869803	HPAFII	viability after 31 days	AGCCGATGGTGCGCGCAGACAGG	IRS2	ENSG00000185950	0.05350030155547736	[413]	[321,152,NaN]	0	hSpCas9	negative selection	10043855
109785624	109785647	13	+	27869803	HPAFII	viability after 31 days	TGACCAGGTCGGTGAGCGCGCGG	IRS2	ENSG00000185950	-0.35063411564673486	[457]	[113,296,NaN]	-2	hSpCas9	negative selection	10043856
109785657	109785680	13	-	27869803	HPAFII	viability after 31 days	CGCCGAGAACGAGCAGGAGCAGG	IRS2	ENSG00000185950	-0.681868252684603	[220]	[61,93,NaN]	-4	hSpCas9	negative selection	10043857
109785893	109785916	13	-	27869803	HPAFII	viability after 31 days	TTCTTCGTGCTGCGCGGACCCGG	IRS2	ENSG00000185950	0.10117249766440561	[240]	[90,203,NaN]	0	hSpCas9	negative selection	10043858
109783933	109783956	13	+	28162770	P31FUJ	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	-1.353554363874989	[136]	[62]	-7	hSpCas9	negative selection	10175813
109784163	109784186	13	-	28162770	P31FUJ	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-3.1620291300009975	[715]	[93]	-9	hSpCas9	negative selection	10175814
109783694	109783717	13	+	28162770	P31FUJ	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-1.325060712266367	[112]	[52]	-7	hSpCas9	negative selection	10175815
109782785	109782808	13	+	28162770	P31FUJ	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	-1.4958366102481726	[47]	[19]	-7	hSpCas9	negative selection	10175816
109785681	109785704	13	-	28162770	P31FUJ	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	-0.9070320432326222	[74]	[46]	-6	hSpCas9	negative selection	10175817
109785297	109785320	13	+	28162770	P31FUJ	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-1.308466474346451	[410]	[194]	-7	hSpCas9	negative selection	10175818
109785234	109785257	13	+	28162770	P31FUJ	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-1.5599669476678881	[137]	[54]	-7	hSpCas9	negative selection	10175819
109785060	109785083	13	+	28162770	P31FUJ	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	-0.22183108659337547	[392]	[395]	-2	hSpCas9	negative selection	10175820
109784505	109784528	13	+	28162770	P31FUJ	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	0.072052377114042	[50]	[62]	0	hSpCas9	negative selection	10175821
109784176	109784199	13	+	28162770	P31FUJ	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	-0.5129101236071141	[679]	[559]	-4	hSpCas9	negative selection	10175822
109783933	109783956	13	+	28162770	TF1	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	NaN	[NaN]	[75]	1	hSpCas9	negative selection	10345179
109784163	109784186	13	-	28162770	TF1	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	NaN	[NaN]	[126]	1	hSpCas9	negative selection	10345180
109783694	109783717	13	+	28162770	TF1	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10345181
109782785	109782808	13	+	28162770	TF1	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	NaN	[NaN]	[33]	1	hSpCas9	negative selection	10345182
109785681	109785704	13	-	28162770	TF1	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	NaN	[NaN]	[105]	1	hSpCas9	negative selection	10345183
109785297	109785320	13	+	28162770	TF1	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	NaN	[NaN]	[332]	1	hSpCas9	negative selection	10345184
109785234	109785257	13	+	28162770	TF1	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10345185
109785060	109785083	13	+	28162770	TF1	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	NaN	[NaN]	[254]	1	hSpCas9	negative selection	10345186
109784505	109784528	13	+	28162770	TF1	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	NaN	[NaN]	[107]	1	hSpCas9	negative selection	10345187
109784176	109784199	13	+	28162770	TF1	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	NaN	[NaN]	[664]	1	hSpCas9	negative selection	10345188
109783933	109783956	13	+	28162770	SKM1	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	-4.069929211465591	[37]	[3]	-9	hSpCas9	negative selection	10514545
109784163	109784186	13	-	28162770	SKM1	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-4.059040895322855	[131]	[13]	-9	hSpCas9	negative selection	10514546
109783694	109783717	13	+	28162770	SKM1	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-2.8663958173804587	[32]	[7]	-9	hSpCas9	negative selection	10514547
109782785	109782808	13	+	28162770	SKM1	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	-0.1699250014423126	[13]	[21]	-1	hSpCas9	negative selection	10514548
109785681	109785704	13	-	28162770	SKM1	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	-1.1115083152169905	[21]	[17]	-7	hSpCas9	negative selection	10514549
109785297	109785320	13	+	28162770	SKM1	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-4.087346264543	[124]	[12]	-9	hSpCas9	negative selection	10514550
109785234	109785257	13	+	28162770	SKM1	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-5.822001698022005	[31]	[0]	-9	hSpCas9	negative selection	10514551
109785060	109785083	13	+	28162770	SKM1	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	-2.6607207909889445	[92]	[25]	-9	hSpCas9	negative selection	10514552
109784505	109784528	13	+	28162770	SKM1	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	-4.406964198743161	[11]	[0]	-9	hSpCas9	negative selection	10514553
109784176	109784199	13	+	28162770	SKM1	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	-1.8321259152957128	[142]	[70]	-8	hSpCas9	negative selection	10514554
109783933	109783956	13	+	28162770	SKM1	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	-4.069929211465591	[37]	[3]	-9	hSpCas9	negative selection	10683911
109784163	109784186	13	-	28162770	SKM1	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-4.059040895322855	[131]	[13]	-9	hSpCas9	negative selection	10683912
109783694	109783717	13	+	28162770	SKM1	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-2.8663958173804587	[32]	[7]	-9	hSpCas9	negative selection	10683913
109782785	109782808	13	+	28162770	SKM1	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	-0.1699250014423126	[13]	[21]	-1	hSpCas9	negative selection	10683914
109785681	109785704	13	-	28162770	SKM1	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	-1.1115083152169905	[21]	[17]	-7	hSpCas9	negative selection	10683915
109785297	109785320	13	+	28162770	SKM1	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-4.087346264543	[124]	[12]	-9	hSpCas9	negative selection	10683916
109785234	109785257	13	+	28162770	SKM1	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-5.822001698022005	[31]	[0]	-9	hSpCas9	negative selection	10683917
109785060	109785083	13	+	28162770	SKM1	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	-2.6607207909889445	[92]	[25]	-9	hSpCas9	negative selection	10683918
109784505	109784528	13	+	28162770	SKM1	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	-4.406964198743161	[11]	[0]	-9	hSpCas9	negative selection	10683919
109784176	109784199	13	+	28162770	SKM1	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	-1.8321259152957128	[142]	[70]	-8	hSpCas9	negative selection	10683920
109783933	109783956	13	+	28162770	PL21	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	-2.462825398233109	[113]	[8]	-9	hSpCas9	negative selection	10853277
109784163	109784186	13	-	28162770	PL21	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-3.5058382871932023	[521]	[19]	-9	hSpCas9	negative selection	10853278
109783694	109783717	13	+	28162770	PL21	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-2.4437165752854044	[99]	[7]	-9	hSpCas9	negative selection	10853279
109782785	109782808	13	+	28162770	PL21	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	2.5452751005380074	[36]	[93]	9	hSpCas9	negative selection	10853280
109785681	109785704	13	-	28162770	PL21	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	-1.1560041957359553	[127]	[24]	-6	hSpCas9	negative selection	10853281
109785297	109785320	13	+	28162770	PL21	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-2.3590926111384185	[388]	[32]	-8	hSpCas9	negative selection	10853282
109785234	109785257	13	+	28162770	PL21	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-5.42921700559029	[98]	[0]	-9	hSpCas9	negative selection	10853283
109785060	109785083	13	+	28162770	PL21	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	-1.667756849503335	[291]	[39]	-8	hSpCas9	negative selection	10853284
109784505	109784528	13	+	28162770	PL21	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	-1.6873856562522676	[36]	[4]	-8	hSpCas9	negative selection	10853285
109784176	109784199	13	+	28162770	PL21	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	-2.013131416878579	[472]	[50]	-8	hSpCas9	negative selection	10853286
109783933	109783956	13	+	28162770	P31FUJ	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	-1.353554363874989	[136]	[62]	-7	hSpCas9	negative selection	11022643
109784163	109784186	13	-	28162770	P31FUJ	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-3.1620291300009975	[715]	[93]	-9	hSpCas9	negative selection	11022644
109783694	109783717	13	+	28162770	P31FUJ	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-1.325060712266367	[112]	[52]	-7	hSpCas9	negative selection	11022645
109782785	109782808	13	+	28162770	P31FUJ	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	-1.4958366102481726	[47]	[19]	-7	hSpCas9	negative selection	11022646
109785681	109785704	13	-	28162770	P31FUJ	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	-0.9070320432326222	[74]	[46]	-6	hSpCas9	negative selection	11022647
109785297	109785320	13	+	28162770	P31FUJ	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-1.308466474346451	[410]	[194]	-7	hSpCas9	negative selection	11022648
109785234	109785257	13	+	28162770	P31FUJ	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-1.5599669476678881	[137]	[54]	-7	hSpCas9	negative selection	11022649
109785060	109785083	13	+	28162770	P31FUJ	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	-0.22183108659337547	[392]	[395]	-2	hSpCas9	negative selection	11022650
109784505	109784528	13	+	28162770	P31FUJ	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	0.072052377114042	[50]	[62]	0	hSpCas9	negative selection	11022651
109784176	109784199	13	+	28162770	P31FUJ	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	-0.5129101236071141	[679]	[559]	-4	hSpCas9	negative selection	11022652
109783933	109783956	13	+	28162770	OCIAML5	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	-1.7711465754804294	[103]	[54]	-7	hSpCas9	negative selection	11192009
109784163	109784186	13	-	28162770	OCIAML5	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-2.986909113150864	[324]	[73]	-8	hSpCas9	negative selection	11192010
109783694	109783717	13	+	28162770	OCIAML5	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-2.8520665708639967	[31]	[7]	-8	hSpCas9	negative selection	11192011
109782785	109782808	13	+	28162770	OCIAML5	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	1.469861524023365	[5]	[29]	9	hSpCas9	negative selection	11192012
109785681	109785704	13	-	28162770	OCIAML5	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	-3.2305781941177267	[25]	[4]	-9	hSpCas9	negative selection	11192013
109785297	109785320	13	+	28162770	OCIAML5	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-2.735552562137572	[213]	[57]	-8	hSpCas9	negative selection	11192014
109785234	109785257	13	+	28162770	OCIAML5	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-3.0999940843075824	[37]	[7]	-9	hSpCas9	negative selection	11192015
109785060	109785083	13	+	28162770	OCIAML5	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	-0.3008246879868419	[201]	[295]	-2	hSpCas9	negative selection	11192016
109784505	109784528	13	+	28162770	OCIAML5	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	-3.7589571664725154	[14]	[1]	-9	hSpCas9	negative selection	11192017
109784176	109784199	13	+	28162770	OCIAML5	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	-1.2638801692685546	[446]	[335]	-6	hSpCas9	negative selection	11192018
109783933	109783956	13	+	28162770	EOL1	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	0.7345313521887531	[234]	[205]	6	hSpCas9	negative selection	11361375
109784163	109784186	13	-	28162770	EOL1	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-2.261318773740799	[636]	[69]	-8	hSpCas9	negative selection	11361376
109783694	109783717	13	+	28162770	EOL1	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-0.41813888348362505	[174]	[68]	-3	hSpCas9	negative selection	11361377
109782785	109782808	13	+	28162770	EOL1	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	1.1300168898705139	[97]	[112]	8	hSpCas9	negative selection	11361378
109785681	109785704	13	-	28162770	EOL1	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	-2.0682206591983894	[198]	[24]	-8	hSpCas9	negative selection	11361379
109785297	109785320	13	+	28162770	EOL1	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-0.6355400605115923	[689]	[233]	-4	hSpCas9	negative selection	11361380
109785234	109785257	13	+	28162770	EOL1	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-0.10346660459906198	[103]	[50]	-1	hSpCas9	negative selection	11361381
109785060	109785083	13	+	28162770	EOL1	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	-0.13259613553307426	[411]	[197]	-1	hSpCas9	negative selection	11361382
109784505	109784528	13	+	28162770	EOL1	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	-0.9499213463456067	[54]	[14]	-6	hSpCas9	negative selection	11361383
109784176	109784199	13	+	28162770	EOL1	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	0.07008861438588787	[715]	[395]	0	hSpCas9	negative selection	11361384
109783933	109783956	13	+	28162770	MOLM13	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	-0.03990525865411765	[181]	[127]	0	hSpCas9	negative selection	11530741
109784163	109784186	13	-	28162770	MOLM13	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-2.5862440555889	[705]	[84]	-8	hSpCas9	negative selection	11530742
109783694	109783717	13	+	28162770	MOLM13	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-0.4973452002947445	[122]	[62]	-3	hSpCas9	negative selection	11530743
109782785	109782808	13	+	28162770	MOLM13	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	0.46788938154457904	[69]	[69]	3	hSpCas9	negative selection	11530744
109785681	109785704	13	-	28162770	MOLM13	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	-1.3038416307823038	[139]	[40]	-6	hSpCas9	negative selection	11530745
109785297	109785320	13	+	28162770	MOLM13	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-0.5496588196662683	[578]	[285]	-3	hSpCas9	negative selection	11530746
109785234	109785257	13	+	28162770	MOLM13	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-0.4949576200379553	[114]	[58]	-3	hSpCas9	negative selection	11530747
109785060	109785083	13	+	28162770	MOLM13	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	-0.24938041128070762	[387]	[235]	-1	hSpCas9	negative selection	11530748
109784505	109784528	13	+	28162770	MOLM13	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	0.12275389549589111	[46]	[36]	0	hSpCas9	negative selection	11530749
109784176	109784199	13	+	28162770	MOLM13	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	-0.09553995762693601	[664]	[449]	0	hSpCas9	negative selection	11530750
109783933	109783956	13	+	28162770	HEL	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	-0.4110324244406238	[163]	[78]	-3	hSpCas9	negative selection	11700107
109784163	109784186	13	-	28162770	HEL	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-2.4220831690558855	[568]	[67]	-8	hSpCas9	negative selection	11700108
109783694	109783717	13	+	28162770	HEL	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-0.3330136217529658	[117]	[59]	-2	hSpCas9	negative selection	11700109
109782785	109782808	13	+	28162770	HEL	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	-1.4276504958910414	[62]	[14]	-7	hSpCas9	negative selection	11700110
109785681	109785704	13	-	28162770	HEL	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	1.1367276726740227	[119]	[168]	8	hSpCas9	negative selection	11700111
109785297	109785320	13	+	28162770	HEL	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-0.5844948524055902	[596]	[254]	-4	hSpCas9	negative selection	11700112
109785234	109785257	13	+	28162770	HEL	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-1.9118500196772803	[93]	[15]	-7	hSpCas9	negative selection	11700113
109785060	109785083	13	+	28162770	HEL	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	0.6658841686482181	[370]	[376]	6	hSpCas9	negative selection	11700114
109784505	109784528	13	+	28162770	HEL	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	-1.2197576442497082	[39]	[10]	-6	hSpCas9	negative selection	11700115
109784176	109784199	13	+	28162770	HEL	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	-0.048938567876019246	[553]	[342]	0	hSpCas9	negative selection	11700116
109783933	109783956	13	+	28162770	MV411	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	0.5305097098531142	[142]	[173]	5	hSpCas9	negative selection	11869473
109784163	109784186	13	-	28162770	MV411	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-1.6587186619944674	[490]	[130]	-7	hSpCas9	negative selection	11869474
109783694	109783717	13	+	28162770	MV411	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	0.49839912431599415	[99]	[118]	4	hSpCas9	negative selection	11869475
109782785	109782808	13	+	28162770	MV411	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	2.1054185459103474	[39]	[144]	9	hSpCas9	negative selection	11869476
109785681	109785704	13	-	28162770	MV411	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	-0.5354643275502899	[116]	[67]	-4	hSpCas9	negative selection	11869477
109785297	109785320	13	+	28162770	MV411	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-0.05187224144256808	[442]	[359]	0	hSpCas9	negative selection	11869478
109785234	109785257	13	+	28162770	MV411	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-0.19313504060320613	[132]	[97]	-1	hSpCas9	negative selection	11869479
109785060	109785083	13	+	28162770	MV411	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	1.1443440578186717	[231]	[431]	8	hSpCas9	negative selection	11869480
109784505	109784528	13	+	28162770	MV411	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	0.9936809585369923	[30]	[51]	8	hSpCas9	negative selection	11869481
109784176	109784199	13	+	28162770	MV411	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	0.7249537616101764	[417]	[581]	6	hSpCas9	negative selection	11869482
109783933	109783956	13	+	28162770	MONOMAC1	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	0.5544648402645329	[78]	[132]	5	hSpCas9	negative selection	12038839
109784163	109784186	13	-	28162770	MONOMAC1	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-0.3764846226203724	[341]	[301]	-3	hSpCas9	negative selection	12038840
109783694	109783717	13	+	28162770	MONOMAC1	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	0.6627854948921861	[53]	[97]	6	hSpCas9	negative selection	12038841
109782785	109782808	13	+	28162770	MONOMAC1	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	1.1133032735525967	[24]	[61]	8	hSpCas9	negative selection	12038842
109785681	109785704	13	-	28162770	MONOMAC1	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	-0.3270973876239267	[57]	[52]	-3	hSpCas9	negative selection	12038843
109785297	109785320	13	+	28162770	MONOMAC1	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-0.8344667676748453	[307]	[197]	-6	hSpCas9	negative selection	12038844
109785234	109785257	13	+	28162770	MONOMAC1	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-0.3125140644794897	[51]	[47]	-3	hSpCas9	negative selection	12038845
109785060	109785083	13	+	28162770	MONOMAC1	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	-0.44964388144300926	[192]	[161]	-4	hSpCas9	negative selection	12038846
109784505	109784528	13	+	28162770	MONOMAC1	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	1.6020504590144498	[24]	[86]	9	hSpCas9	negative selection	12038847
109784176	109784199	13	+	28162770	MONOMAC1	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	-0.04413794790991421	[321]	[357]	0	hSpCas9	negative selection	12038848
109783933	109783956	13	+	28162770	OCIAML2	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	-0.9192198842320316	[28]	[84]	-6	hSpCas9	negative selection	12208205
109784163	109784186	13	-	28162770	OCIAML2	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-2.5091039730567966	[75]	[73]	-8	hSpCas9	negative selection	12208206
109783694	109783717	13	+	28162770	OCIAML2	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-0.35515260782222513	[17]	[77]	-3	hSpCas9	negative selection	12208207
109782785	109782808	13	+	28162770	OCIAML2	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	0.8221519239856847	[4]	[48]	7	hSpCas9	negative selection	12208208
109785681	109785704	13	-	28162770	OCIAML2	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	-0.8856673245210049	[16]	[50]	-6	hSpCas9	negative selection	12208209
109785297	109785320	13	+	28162770	OCIAML2	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-1.2045549650883165	[78]	[189]	-7	hSpCas9	negative selection	12208210
109785234	109785257	13	+	28162770	OCIAML2	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-0.8856673245210049	[14]	[44]	-6	hSpCas9	negative selection	12208211
109785060	109785083	13	+	28162770	OCIAML2	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	-0.04178652643828695	[51]	[279]	0	hSpCas9	negative selection	12208212
109784505	109784528	13	+	28162770	OCIAML2	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	-1.733664231075955	[11]	[19]	-8	hSpCas9	negative selection	12208213
109784176	109784199	13	+	28162770	OCIAML2	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	-0.2893000605275994	[83]	[380]	-2	hSpCas9	negative selection	12208214
109783933	109783956	13	+	28162770	OCIAML3	viability	AGGCCCCGCAGAAGGCACGGCGG	IRS2	ENSG00000185950	-0.3716152189877151	[35]	[83]	-3	hSpCas9	negative selection	12377571
109784163	109784186	13	-	28162770	OCIAML3	viability	GGCCTACCACCCCTACCCAGAGG	IRS2	ENSG00000185950	-1.844330994408403	[112]	[94]	-8	hSpCas9	negative selection	12377572
109783694	109783717	13	+	28162770	OCIAML3	viability	GCTGCGGAGAAGAAGTCGGGCGG	IRS2	ENSG00000185950	-0.7076644221197304	[32]	[60]	-5	hSpCas9	negative selection	12377573
109782785	109782808	13	+	28162770	OCIAML3	viability	GGGGCCGCGATAGGTTGCGGCGG	IRS2	ENSG00000185950	-2.841935153767749	[18]	[7]	-9	hSpCas9	negative selection	12377574
109785681	109785704	13	-	28162770	OCIAML3	viability	CAAGGACGAGTACTTCGCCGTGG	IRS2	ENSG00000185950	-1.4870924364076514	[25]	[27]	-7	hSpCas9	negative selection	12377575
109785297	109785320	13	+	28162770	OCIAML3	viability	TGTCCGAGTGGCCGCAGCGGCGG	IRS2	ENSG00000185950	-2.173301390958627	[126]	[84]	-8	hSpCas9	negative selection	12377576
109785234	109785257	13	+	28162770	OCIAML3	viability	CCTGCATCCACAGCTCGCCGGGG	IRS2	ENSG00000185950	-0.5716398272957086	[31]	[64]	-4	hSpCas9	negative selection	12377577
109785060	109785083	13	+	28162770	OCIAML3	viability	GCAGGTTGACCAGGTGGTGGTGG	IRS2	ENSG00000185950	-0.05243773511638772	[89]	[261]	0	hSpCas9	negative selection	12377578
109784505	109784528	13	+	28162770	OCIAML3	viability	GGTGGCTGCAGAAGGCGCGCAGG	IRS2	ENSG00000185950	1.15322628929587	[6]	[46]	8	hSpCas9	negative selection	12377579
109784176	109784199	13	+	28162770	OCIAML3	viability	GTGGTAGGCCACCTTGGGAGAGG	IRS2	ENSG00000185950	0.32387796254228873	[121]	[460]	3	hSpCas9	negative selection	12377580