Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 8471
• Symbol: IRS4
• Description: insulin receptor substrate 4

DataSource: http://genomecrispr.dkfz.de/#!/results/IRS4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
108735896	108735919	X	+	26472758	Jiyoye	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	0.9514958977296837	[71]	[104]	6	hSpCas9	negative selection	79292
108735618	108735641	X	-	26472758	Jiyoye	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.7457997652655495	[188]	[238]	5	hSpCas9	negative selection	79293
108735558	108735581	X	-	26472758	Jiyoye	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	1.092664758180994	[96]	[155]	7	hSpCas9	negative selection	79294
108734891	108734914	X	-	26472758	Jiyoye	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	0.29013596031565403	[76]	[70]	2	hSpCas9	negative selection	79295
108734750	108734773	X	-	26472758	Jiyoye	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	0.9002153927859902	[26]	[37]	6	hSpCas9	negative selection	79296
108735870	108735893	X	+	26472758	Jiyoye	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	0.5624536069837843	[43]	[48]	4	hSpCas9	negative selection	79297
108735807	108735830	X	-	26472758	Jiyoye	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	-0.3457317565293543	[181]	[107]	-2	hSpCas9	negative selection	79298
108735738	108735761	X	+	26472758	Jiyoye	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	1.6511009643919625	[18]	[44]	8	hSpCas9	negative selection	79299
108735896	108735919	X	+	26472758	KBM7	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	1.1282098313236282	[374,209]	[228,350]	9	hSpCas9	negative selection	270410
108735618	108735641	X	-	26472758	KBM7	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.8744298796029212	[854,672]	[535,758]	8	hSpCas9	negative selection	270411
108735558	108735581	X	-	26472758	KBM7	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.7000027261983671	[629,473]	[566,283]	7	hSpCas9	negative selection	270412
108734891	108734914	X	-	26472758	KBM7	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	-0.5724902340950513	[210,197]	[106,26]	-5	hSpCas9	negative selection	270413
108734750	108734773	X	-	26472758	KBM7	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-2.0462098935433146	[247,127]	[14,25]	-8	hSpCas9	negative selection	270414
108735870	108735893	X	+	26472758	KBM7	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	0.6516700261344759	[188,176]	[165,107]	7	hSpCas9	negative selection	270415
108735807	108735830	X	-	26472758	KBM7	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	0.19963586726299357	[541,440]	[246,278]	2	hSpCas9	negative selection	270416
108735738	108735761	X	+	26472758	KBM7	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	0.045828863255574004	[267,285]	[162,110]	0	hSpCas9	negative selection	270417
108735896	108735919	X	+	26472758	Raji	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	0.3663018327351615	[116]	[34]	3	hSpCas9	negative selection	461528
108735618	108735641	X	-	26472758	Raji	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.9856145720859398	[382]	[175]	8	hSpCas9	negative selection	461529
108735558	108735581	X	-	26472758	Raji	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.04061452316089853	[397]	[94]	0	hSpCas9	negative selection	461530
108734891	108734914	X	-	26472758	Raji	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	1.1073835353735997	[47]	[23]	8	hSpCas9	negative selection	461531
108734750	108734773	X	-	26472758	Raji	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-1.3188812193284984	[85]	[7]	-7	hSpCas9	negative selection	461532
108735870	108735893	X	+	26472758	Raji	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	0.937458533931287	[107]	[47]	8	hSpCas9	negative selection	461533
108735807	108735830	X	-	26472758	Raji	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	0.4817790501550974	[215]	[69]	4	hSpCas9	negative selection	461534
108735738	108735761	X	+	26472758	Raji	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	0.3995642868669096	[97]	[29]	4	hSpCas9	negative selection	461535
108735896	108735919	X	+	26472758	K562	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	0.6447796503128466	[246]	[325]	5	hSpCas9	negative selection	652646
108735618	108735641	X	-	26472758	K562	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.7289070130877331	[658]	[921]	6	hSpCas9	negative selection	652647
108735558	108735581	X	-	26472758	K562	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.28730454051962334	[463]	[477]	2	hSpCas9	negative selection	652648
108734891	108734914	X	-	26472758	K562	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	-0.7230134098771225	[218]	[111]	-4	hSpCas9	negative selection	652649
108734750	108734773	X	-	26472758	K562	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-6.549997138683658	[110]	[0]	-9	hSpCas9	negative selection	652650
108735870	108735893	X	+	26472758	K562	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	-2.4336531774461907	[159]	[24]	-8	hSpCas9	negative selection	652651
108735807	108735830	X	-	26472758	K562	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	1.275682941183298	[387]	[792]	9	hSpCas9	negative selection	652652
108735738	108735761	X	+	26472758	K562	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	0.6051660714443374	[175]	[225]	5	hSpCas9	negative selection	652653
108732778	108732801	X	+	26627737	DLD1	viability	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	0.06091896708490929	[207]	[113,69,25]	0	hSpCas9	negative selection	844041
108732859	108732882	X	-	26627737	DLD1	viability	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	-0.0023703182473641116	[363]	[83,67,176]	0	hSpCas9	negative selection	844042
108734066	108734089	X	+	26627737	DLD1	viability	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	1.4796496446002367	[166]	[62,338,56]	9	hSpCas9	negative selection	844043
108735427	108735450	X	+	26627737	DLD1	viability	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.023605958379564473	[2098]	[736,566,688]	0	hSpCas9	negative selection	844044
108735783	108735806	X	-	26627737	DLD1	viability	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	1.5991760006090279	[66]	[54,96,42]	9	hSpCas9	negative selection	844045
108735893	108735916	X	+	26627737	DLD1	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.7391147528142279	[343]	[317,208,34]	7	hSpCas9	negative selection	844046
108732778	108732801	X	+	26627737	GBM cells	viability after 5 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	0.7118283222851902	[73]	[64,64]	8	hSpCas9	negative selection	926356
108732859	108732882	X	-	26627737	GBM cells	viability after 5 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	0.10005374699353708	[126]	[96,48]	1	hSpCas9	negative selection	926357
108734066	108734089	X	+	26627737	GBM cells	viability after 5 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	0.5105584182593473	[124]	[96,93]	7	hSpCas9	negative selection	926358
108735427	108735450	X	+	26627737	GBM cells	viability after 5 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	-0.5761552582032066	[915]	[337,320]	-7	hSpCas9	negative selection	926359
108735783	108735806	X	-	26627737	GBM cells	viability after 5 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	0.47382271094291906	[95]	[82,59]	7	hSpCas9	negative selection	926360
108735893	108735916	X	+	26627737	GBM cells	viability after 5 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.35457976373850214	[210]	[120,55]	-5	hSpCas9	negative selection	926361
108732778	108732801	X	+	26627737	GBM cells	viability after 13 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	0.33568455879823844	[73]	[80,25]	4	hSpCas9	negative selection	1008671
108732859	108732882	X	-	26627737	GBM cells	viability after 13 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	0.3571831991542306	[126]	[138,46]	4	hSpCas9	negative selection	1008672
108734066	108734089	X	+	26627737	GBM cells	viability after 13 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	0.9935272732850411	[124]	[139,130]	9	hSpCas9	negative selection	1008673
108735427	108735450	X	+	26627737	GBM cells	viability after 13 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	-0.5736822460723503	[915]	[339,328]	-6	hSpCas9	negative selection	1008674
108735783	108735806	X	-	26627737	GBM cells	viability after 13 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	0.03721897177945466	[95]	[53,52]	0	hSpCas9	negative selection	1008675
108735893	108735916	X	+	26627737	GBM cells	viability after 13 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.31635684337941267	[210]	[113,73]	-4	hSpCas9	negative selection	1008676
108732778	108732801	X	+	26627737	GBM cells	viability after 21 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	0.37245219815824915	[73]	[50,52]	4	hSpCas9	negative selection	1090986
108732859	108732882	X	-	26627737	GBM cells	viability after 21 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	0.4177217823570435	[126]	[99,84]	4	hSpCas9	negative selection	1090987
108734066	108734089	X	+	26627737	GBM cells	viability after 21 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	0.7412799405854215	[124]	[112,113]	7	hSpCas9	negative selection	1090988
108735427	108735450	X	+	26627737	GBM cells	viability after 21 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	-0.6390475294843003	[915]	[329,309]	-5	hSpCas9	negative selection	1090989
108735783	108735806	X	-	26627737	GBM cells	viability after 21 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	0.1510390711329621	[95]	[59,55]	1	hSpCas9	negative selection	1090990
108735893	108735916	X	+	26627737	GBM cells	viability after 21 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.8108732102592695	[210]	[68,61]	-6	hSpCas9	negative selection	1090991
108732778	108732801	X	+	26627737	RPE1	viability after 9 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	-0.4371919478265722	[378]	[29,161]	-3	hSpCas9	negative selection	1173301
108732859	108732882	X	-	26627737	RPE1	viability after 9 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	0.9136536720612137	[409]	[112,407]	6	hSpCas9	negative selection	1173302
108734066	108734089	X	+	26627737	RPE1	viability after 9 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	1.3358791472952989	[163]	[119,141]	7	hSpCas9	negative selection	1173303
108735427	108735450	X	+	26627737	RPE1	viability after 9 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.5582976785328679	[2243]	[1061,998]	4	hSpCas9	negative selection	1173304
108735783	108735806	X	-	26627737	RPE1	viability after 9 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	-0.018919049525333964	[226]	[77,59]	0	hSpCas9	negative selection	1173305
108735893	108735916	X	+	26627737	RPE1	viability after 9 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	1.7029258520144854	[270]	[194,380]	8	hSpCas9	negative selection	1173306
108732778	108732801	X	+	26627737	RPE1	viability after 12 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	-0.31843544234710386	[378]	[52,111]	-2	hSpCas9	negative selection	1255616
108732859	108732882	X	-	26627737	RPE1	viability after 12 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	0.6479199664592847	[409]	[124,222]	4	hSpCas9	negative selection	1255617
108734066	108734089	X	+	26627737	RPE1	viability after 12 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	1.862289744576402	[163]	[166,152]	8	hSpCas9	negative selection	1255618
108735427	108735450	X	+	26627737	RPE1	viability after 12 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.2958587044219445	[2243]	[811,663]	2	hSpCas9	negative selection	1255619
108735783	108735806	X	-	26627737	RPE1	viability after 12 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	-1.0331966500429777	[226]	[22,36]	-6	hSpCas9	negative selection	1255620
108735893	108735916	X	+	26627737	RPE1	viability after 12 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	1.887109319389652	[270]	[262,275]	8	hSpCas9	negative selection	1255621
108732778	108732801	X	+	26627737	RPE1	viability after 15 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	0.2618527052520928	[378]	[153,103]	1	hSpCas9	negative selection	1337931
108732859	108732882	X	-	26627737	RPE1	viability after 15 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	0.7974554498632722	[409]	[140,259]	5	hSpCas9	negative selection	1337932
108734066	108734089	X	+	26627737	RPE1	viability after 15 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	1.6166996785831311	[163]	[126,156]	8	hSpCas9	negative selection	1337933
108735427	108735450	X	+	26627737	RPE1	viability after 15 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.28639369920026647	[2243]	[820,728]	1	hSpCas9	negative selection	1337934
108735783	108735806	X	-	26627737	RPE1	viability after 15 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	-1.900349097076343	[226]	[33,0]	-8	hSpCas9	negative selection	1337935
108735893	108735916	X	+	26627737	RPE1	viability after 15 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	2.1715464349856983	[270]	[493,201]	9	hSpCas9	negative selection	1337936
108732778	108732801	X	+	26627737	RPE1	viability after 18 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	-0.5200091002431078	[378]	[109,29]	-3	hSpCas9	negative selection	1420246
108732859	108732882	X	-	26627737	RPE1	viability after 18 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	0.3552570732171325	[409]	[98,186]	2	hSpCas9	negative selection	1420247
108734066	108734089	X	+	26627737	RPE1	viability after 18 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	1.6684635594315043	[163]	[116,165]	8	hSpCas9	negative selection	1420248
108735427	108735450	X	+	26627737	RPE1	viability after 18 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.18229603547949447	[2243]	[676,697]	1	hSpCas9	negative selection	1420249
108735783	108735806	X	-	26627737	RPE1	viability after 18 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	-2.4388108954351955	[226]	[19,1]	-8	hSpCas9	negative selection	1420250
108735893	108735916	X	+	26627737	RPE1	viability after 18 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	2.0102581628924057	[270]	[443,134]	8	hSpCas9	negative selection	1420251
108732778	108732801	X	+	26627737	HeLa	viability after 8 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	-1.177356710064877	[367]	[102,67,49]	-8	hSpCas9	negative selection	1502561
108732859	108732882	X	-	26627737	HeLa	viability after 8 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	1.495323568341662	[173]	[193,256,186]	9	hSpCas9	negative selection	1502562
108734066	108734089	X	+	26627737	HeLa	viability after 8 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	0.295682668467261	[220]	[65,133,140]	3	hSpCas9	negative selection	1502563
108735427	108735450	X	+	26627737	HeLa	viability after 8 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.05501921845073299	[1259]	[708,661,381]	0	hSpCas9	negative selection	1502564
108735783	108735806	X	-	26627737	HeLa	viability after 8 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	-2.152056663393292	[292]	[16,0,62]	-9	hSpCas9	negative selection	1502565
108735893	108735916	X	+	26627737	HeLa	viability after 8 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.19785421737946474	[505]	[244,171,171]	-2	hSpCas9	negative selection	1502566
108732778	108732801	X	+	26627737	HeLa	viability after 12 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	-0.6471526013373018	[367]	[116,133,36]	-5	hSpCas9	negative selection	1584876
108732859	108732882	X	-	26627737	HeLa	viability after 12 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	0.5512113838445456	[173]	[114,108,91]	4	hSpCas9	negative selection	1584877
108734066	108734089	X	+	26627737	HeLa	viability after 12 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	0.19359610243572922	[220]	[77,90,144]	1	hSpCas9	negative selection	1584878
108735427	108735450	X	+	26627737	HeLa	viability after 12 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.19491143732375815	[1259]	[539,694,540]	1	hSpCas9	negative selection	1584879
108735783	108735806	X	-	26627737	HeLa	viability after 12 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	-1.5815983529196669	[292]	[49,55,13]	-8	hSpCas9	negative selection	1584880
108735893	108735916	X	+	26627737	HeLa	viability after 12 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.34727171042209004	[505]	[250,94,156]	-3	hSpCas9	negative selection	1584881
108732778	108732801	X	+	26627737	HeLa	viability after 15 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	0.1935943896533447	[367]	[93,333,79]	1	hSpCas9	negative selection	1667191
108732859	108732882	X	-	26627737	HeLa	viability after 15 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	1.5848329667325936	[173]	[268,139,228]	9	hSpCas9	negative selection	1667192
108734066	108734089	X	+	26627737	HeLa	viability after 15 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	-0.18688671348630892	[220]	[110,30,95]	-1	hSpCas9	negative selection	1667193
108735427	108735450	X	+	26627737	HeLa	viability after 15 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.03040966141272916	[1259]	[454,611,503]	0	hSpCas9	negative selection	1667194
108735783	108735806	X	-	26627737	HeLa	viability after 15 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	-0.20577256670789507	[292]	[177,79,46]	-2	hSpCas9	negative selection	1667195
108735893	108735916	X	+	26627737	HeLa	viability after 15 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.260633726454758	[505]	[274,109,125]	-2	hSpCas9	negative selection	1667196
108732778	108732801	X	+	26627737	HeLa	viability after 18 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	0.2034336542239592	[367]	[64,276,79]	1	hSpCas9	negative selection	1749506
108732859	108732882	X	-	26627737	HeLa	viability after 18 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	1.5847311247174316	[173]	[181,113,228]	8	hSpCas9	negative selection	1749507
108734066	108734089	X	+	26627737	HeLa	viability after 18 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	-0.1926453592624776	[220]	[71,27,95]	-2	hSpCas9	negative selection	1749508
108735427	108735450	X	+	26627737	HeLa	viability after 18 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.03649649310631098	[1259]	[318,494,503]	0	hSpCas9	negative selection	1749509
108735783	108735806	X	-	26627737	HeLa	viability after 18 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	-0.181776782802979	[292]	[122,65,46]	-1	hSpCas9	negative selection	1749510
108735893	108735916	X	+	26627737	HeLa	viability after 18 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.19314597907725828	[505]	[202,87,125]	-2	hSpCas9	negative selection	1749511
108732778	108732801	X	+	26627737	HCT116	viability after 6 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	-2.578667256256018	[113]	[2,2]	-9	hSpCas9	negative selection	1831821
108732859	108732882	X	-	26627737	HCT116	viability after 6 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	-1.0636482338092514	[275]	[3,29]	-6	hSpCas9	negative selection	1831822
108734066	108734089	X	+	26627737	HCT116	viability after 6 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	2.260308142575159	[221]	[143,179]	9	hSpCas9	negative selection	1831823
108735427	108735450	X	+	26627737	HCT116	viability after 6 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	1.6219787148939695	[1319]	[581,669]	8	hSpCas9	negative selection	1831824
108735783	108735806	X	-	26627737	HCT116	viability after 6 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	0.101681274886532	[397]	[41,80]	0	hSpCas9	negative selection	1831825
108735893	108735916	X	+	26627737	HCT116	viability after 6 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.7908662373720154	[495]	[170,114]	4	hSpCas9	negative selection	1831826
108732778	108732801	X	+	26627737	HCT116	viability after 8 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	1.5234234026313112	[47]	[117,46,63]	9	hSpCas9	negative selection	1914136
108732859	108732882	X	-	26627737	HCT116	viability after 8 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	0.5850878325530652	[117]	[103,112,75]	6	hSpCas9	negative selection	1914137
108734066	108734089	X	+	26627737	HCT116	viability after 8 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	0.6554255199771817	[117]	[110,143,52]	6	hSpCas9	negative selection	1914138
108735427	108735450	X	+	26627737	HCT116	viability after 8 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.7121732568445981	[483]	[431,385,491]	6	hSpCas9	negative selection	1914139
108735783	108735806	X	-	26627737	HCT116	viability after 8 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	4.189164345799512	[13]	[159,161,100]	9	hSpCas9	negative selection	1914140
108735893	108735916	X	+	26627737	HCT116	viability after 8 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.004696173757552227	[306]	[199,82,225]	0	hSpCas9	negative selection	1914141
108732778	108732801	X	+	26627737	HCT116	viability after 9 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	1.1622360648258554	[113]	[147,4]	7	hSpCas9	negative selection	1996451
108732859	108732882	X	-	26627737	HCT116	viability after 9 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	2.0333630028820675	[275]	[318,287]	9	hSpCas9	negative selection	1996452
108734066	108734089	X	+	26627737	HCT116	viability after 9 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	-1.1939939609074455	[221]	[21,28]	-7	hSpCas9	negative selection	1996453
108735427	108735450	X	+	26627737	HCT116	viability after 9 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.9872769137517017	[1319]	[767,643]	6	hSpCas9	negative selection	1996454
108735783	108735806	X	-	26627737	HCT116	viability after 9 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	0.703894680409879	[397]	[152,188]	5	hSpCas9	negative selection	1996455
108735893	108735916	X	+	26627737	HCT116	viability after 9 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.7534408514892126	[495]	[110,311]	5	hSpCas9	negative selection	1996456
108732778	108732801	X	+	26627737	HCT116	viability after 12 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	1.6663934808311165	[47]	[92,76,68]	9	hSpCas9	negative selection	2078766
108732859	108732882	X	-	26627737	HCT116	viability after 12 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	0.9939747649864782	[117]	[56,190,129]	8	hSpCas9	negative selection	2078767
108734066	108734089	X	+	26627737	HCT116	viability after 12 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	0.8792576025525944	[117]	[145,138,54]	7	hSpCas9	negative selection	2078768
108735427	108735450	X	+	26627737	HCT116	viability after 12 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	1.2655196131382325	[483]	[656,548,622]	8	hSpCas9	negative selection	2078769
108735783	108735806	X	-	26627737	HCT116	viability after 12 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	4.559014883280129	[13]	[89,147,288]	9	hSpCas9	negative selection	2078770
108735893	108735916	X	+	26627737	HCT116	viability after 12 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.21731272945547148	[306]	[213,130,213]	2	hSpCas9	negative selection	2078771
108732778	108732801	X	+	26627737	HCT116	viability after 15 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	2.126811128365632	[47]	[106,85,165]	9	hSpCas9	negative selection	2161081
108732859	108732882	X	-	26627737	HCT116	viability after 15 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	0.9499429223449125	[117]	[85,147,152]	7	hSpCas9	negative selection	2161082
108734066	108734089	X	+	26627737	HCT116	viability after 15 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	1.0259237182879706	[117]	[272,68,88]	8	hSpCas9	negative selection	2161083
108735427	108735450	X	+	26627737	HCT116	viability after 15 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	1.3900251779387394	[483]	[703,627,848]	9	hSpCas9	negative selection	2161084
108735783	108735806	X	-	26627737	HCT116	viability after 15 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	3.2927230968928844	[13]	[89,90,56]	9	hSpCas9	negative selection	2161085
108735893	108735916	X	+	26627737	HCT116	viability after 15 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.16467981539677753	[306]	[232,83,163]	-2	hSpCas9	negative selection	2161086
108732778	108732801	X	+	26627737	HCT116	viability after 18 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	1.4337206923109553	[47]	[69,25,95]	8	hSpCas9	negative selection	2243396
108732859	108732882	X	-	26627737	HCT116	viability after 18 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	1.0235407511096999	[117]	[32,174,136]	7	hSpCas9	negative selection	2243397
108734066	108734089	X	+	26627737	HCT116	viability after 18 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	1.0125729351548158	[117]	[210,60,74]	7	hSpCas9	negative selection	2243398
108735427	108735450	X	+	26627737	HCT116	viability after 18 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	1.1155962553607952	[483]	[432,400,702]	8	hSpCas9	negative selection	2243399
108735783	108735806	X	-	26627737	HCT116	viability after 18 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	3.591848699501477	[13]	[108,85,47]	9	hSpCas9	negative selection	2243400
108735893	108735916	X	+	26627737	HCT116	viability after 18 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.37653407130234756	[306]	[324,35,228]	3	hSpCas9	negative selection	2243401
108735478	108735501	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCCGAGTGTCCACAGCGACGG	IRS4	ENSG00000133124	-0.8431323980349268	[2,2]	[1,0]	-8	hSpCas9	positive selection	2995996
108735894	108735917	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.4588905669416771	[3,3]	[5,2]	8	hSpCas9	positive selection	2995997
108735478	108735501	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCCGAGTGTCCACAGCGACGG	IRS4	ENSG00000133124	0.181808047984727	[2,2]	[2,1]	3	hSpCas9	positive selection	3063854
108735894	108735917	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.526810405814658	[3,3]	[2,0]	-7	hSpCas9	positive selection	3063855
108735807	108735830		+	24336571	A375	resistance to PLX after 7 days	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.232320625621541	[5,4]	[5,7]	6	hSpCas9	positive selection	3121618
108735893	108735916		+	24336571	A375	resistance to PLX after 7 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.09829253807483196	[7,6]	[7,7]	3	hSpCas9	positive selection	3121619
108735807	108735830		+	24336571	A375	resistance to PLX after 14 days	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	2.351084364322625	[4,5]	[10,15]	9	hSpCas9	positive selection	3179411
108735893	108735916		+	24336571	A375	resistance to PLX after 14 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.05961102279694708	[8,5]	[2,2]	0	hSpCas9	positive selection	3179412
108735807	108735830		+	24336571	A375	viability after 7 days	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	-0.313233393045275	[7]	[5,4]	-4	hSpCas9	negative selection	3237204
108735893	108735916		+	24336571	A375	viability after 7 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.09848562317525156	[6]	[7,6]	1	hSpCas9	negative selection	3237205
108735807	108735830		+	24336571	A375	viability after 14 days	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	-0.32649950386241333	[7]	[4,5]	-4	hSpCas9	negative selection	3294997
108735893	108735916		+	24336571	A375	viability after 14 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.07572488362138685	[6]	[8,5]	1	hSpCas9	negative selection	3294998
108734233	108734256	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	1.4244361972810935	[56,56]	[0,0]	6	hSpCas9	positive selection	3374655
108733499	108733522	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	1.7027373597681978	[46,46]	[0,0]	7	hSpCas9	positive selection	3374656
108735477	108735500	X	+	26780180	HT29	viability (Avana library 4 designs)	GCTCCGAGTGTCCACAGCGACGG	IRS4	ENSG00000133124	1.7255471678981	[]	[]	6	hSpCas9	negative selection	3433385
108735893	108735916	X	+	26780180	HT29	viability (Avana library 4 designs)	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.663207722742541	[]	[]	2	hSpCas9	negative selection	3433386
108735893	108735916	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	1.07337710294411	[]	[]	1	hSpCas9	negative selection	3519970
108735477	108735500	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCGAGTGTCCACAGCGACGG	IRS4	ENSG00000133124	5.95457251536246	[]	[]	9	hSpCas9	negative selection	3519971
108735910	108735933	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCCCCCCGCTCATTCCACCGCGG	IRS4	ENSG00000133124	3.19771223478767	[]	[]	5	hSpCas9	negative selection	3519972
108735590	108735613	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCACAGAAAAGAGCTGAGCGG	IRS4	ENSG00000133124	1.05293539921944	[]	[]	1	hSpCas9	negative selection	3519973
108735893	108735916	X	+	26780180	A375	viability (Avana lentiGuide)	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	3.96741864034315	[]	[]	4	hSpCas9	negative selection	3628629
108735477	108735500	X	+	26780180	A375	viability (Avana lentiGuide)	GCTCCGAGTGTCCACAGCGACGG	IRS4	ENSG00000133124	1.16045910783112	[]	[]	1	hSpCas9	negative selection	3628630
108735910	108735933	X	-	26780180	A375	viability (Avana lentiGuide)	TCCCCCCGCTCATTCCACCGCGG	IRS4	ENSG00000133124	-1.02929574052656	[]	[]	-2	hSpCas9	negative selection	3628631
108735590	108735613	X	-	26780180	A375	viability (Avana lentiGuide)	GGGCACAGAAAAGAGCTGAGCGG	IRS4	ENSG00000133124	-2.88384652543219	[]	[]	-5	hSpCas9	negative selection	3628632
108735893	108735916	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.04650345119688841	[5]	[6,4]	1	hSpCas9	positive selection	3737288
108735477	108735500	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCGAGTGTCCACAGCGACGG	IRS4	ENSG00000133124	0.20106897526172018	[3]	[4,4]	5	hSpCas9	positive selection	3737289
108735910	108735933	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCCCCCGCTCATTCCACCGCGG	IRS4	ENSG00000133124	0.1509928353275709	[4]	[5,4]	4	hSpCas9	positive selection	3737290
108735590	108735613	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCACAGAAAAGAGCTGAGCGG	IRS4	ENSG00000133124	0.2829682260755615	[5]	[7,4]	7	hSpCas9	positive selection	3737291
108735893	108735916	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.22197851949676897	[5]	[3,4]	-3	hSpCas9	positive selection	3845895
108735477	108735500	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCGAGTGTCCACAGCGACGG	IRS4	ENSG00000133124	-0.3354332857388134	[5]	[1,4]	-4	hSpCas9	positive selection	3845896
108735910	108735933	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCCCCCGCTCATTCCACCGCGG	IRS4	ENSG00000133124	0.15623308410856002	[5]	[4,5]	3	hSpCas9	positive selection	3845897
108735590	108735613	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCACAGAAAAGAGCTGAGCGG	IRS4	ENSG00000133124	0.1912431367950749	[6]	[5,5]	5	hSpCas9	positive selection	3845898
108734233	108734256	X	-	26780180	A375	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	1.28630433146652	[]	[]	7	hSpCas9	negative selection	3951914
108735807	108735830	X	+	26780180	A375	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.326301785383063	[]	[]	0	hSpCas9	negative selection	3951915
108735561	108735584	X	-	26780180	A375	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.70015515759665	[]	[]	2	hSpCas9	negative selection	3951916
108733499	108733522	X	+	26780180	A375	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	1.04617712422362	[]	[]	5	hSpCas9	negative selection	3951917
108735893	108735916	X	+	26780180	A375	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	1.46864411262568	[]	[]	8	hSpCas9	negative selection	3951918
108734233	108734256	X	-	26780180	HT29	viability (GeCKOv2 library)	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	1.05006745641684	[]	[]	5	hSpCas9	negative selection	4059880
108735807	108735830	X	+	26780180	HT29	viability (GeCKOv2 library)	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.487632622818511	[]	[]	1	hSpCas9	negative selection	4059881
108735561	108735584	X	-	26780180	HT29	viability (GeCKOv2 library)	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	1.09852880344219	[]	[]	5	hSpCas9	negative selection	4059882
108733499	108733522	X	+	26780180	HT29	viability (GeCKOv2 library)	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	1.00223559923786	[]	[]	4	hSpCas9	negative selection	4059883
108735893	108735916	X	+	26780180	HT29	viability (GeCKOv2 library)	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	2.08073669385348	[]	[]	9	hSpCas9	negative selection	4059884
108735807	108735830	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	1.0481872677921298	[1]	[2,3]	9	hSpCas9	positive selection	4145320
108735893	108735916	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.20267773341864948	[2]	[1,1]	-5	hSpCas9	positive selection	4145321
108735807	108735830	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.7629701874292295	[4]	[0,1,3,3]	5	hSpCas9	positive selection	4209342
108735893	108735916	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	1.1313849067988588	[0]	[4,0,0,0]	8	hSpCas9	positive selection	4209343
108735807	108735830	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.2638039383365947	[3]	[4,3]	5	hSpCas9	positive selection	4277304
108735893	108735916	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.22222378421470457	[2]	[0,1]	-4	hSpCas9	positive selection	4277305
108735561	108735584	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.17071393781717537	[3]	[2,2]	3	hSpCas9	positive selection	4277306
108734233	108734256	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	0.18371626681092912	[3]	[4,2]	3	hSpCas9	positive selection	4341560
108733499	108733522	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.09805455933492416	[2]	[2,1]	2	hSpCas9	positive selection	4341562
108735561	108735583	X	-	27760321	OCIAML3	viability	CGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.19516790838451797	[611,490]	[447,546]	2	hSpCas9	negative selection	4410339
108735804	108735826	X	-	27760321	OCIAML3	viability	GACGAATACTTCGCGATGGTGG	IRS4	ENSG00000133124	0.07079579626153626	[604,454]	[340,549]	0	hSpCas9	negative selection	4410340
108735894	108735916	X	+	27760321	OCIAML3	viability	ATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.529545465105612	[879,677]	[763,1014]	6	hSpCas9	negative selection	4410341
108735561	108735583	X	-	27760321	OCIAML2	viability	CGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.5523339437919759	[611,490]	[451,911]	7	hSpCas9	negative selection	4493802
108735804	108735826	X	-	27760321	OCIAML2	viability	GACGAATACTTCGCGATGGTGG	IRS4	ENSG00000133124	-0.08295753759343069	[604,454]	[381,426]	-1	hSpCas9	negative selection	4493803
108735894	108735916	X	+	27760321	OCIAML2	viability	ATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.11756674110663967	[879,677]	[603,776]	1	hSpCas9	negative selection	4493804
108735561	108735583	X	-	27760321	MV411	viability	CGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	-0.09920307469770204	[611,490]	[346,323]	0	hSpCas9	negative selection	4577265
108735804	108735826	X	-	27760321	MV411	viability	GACGAATACTTCGCGATGGTGG	IRS4	ENSG00000133124	-0.8669847255020606	[604,454]	[148,251]	-5	hSpCas9	negative selection	4577266
108735894	108735916	X	+	27760321	MV411	viability	ATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.27906083397938164	[879,677]	[342,536]	-2	hSpCas9	negative selection	4577267
108735561	108735583	X	-	27760321	HL60	viability	CGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	-0.24544794259789265	[611,490]	[372,382]	-3	hSpCas9	negative selection	4660728
108735804	108735826	X	-	27760321	HL60	viability	GACGAATACTTCGCGATGGTGG	IRS4	ENSG00000133124	-0.022140461177312054	[604,454]	[382,464]	0	hSpCas9	negative selection	4660729
108735894	108735916	X	+	27760321	HL60	viability	ATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-1.0301269157922364	[879,677]	[219,403]	-7	hSpCas9	negative selection	4660730
108735561	108735583	X	-	27760321	HT1080	viability	CGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.5503942489733862	[490,382]	[337,163]	3	hSpCas9	negative selection	4744191
108735804	108735826	X	-	27760321	HT1080	viability	GACGAATACTTCGCGATGGTGG	IRS4	ENSG00000133124	1.1542009012315588	[454,354]	[328,391]	6	hSpCas9	negative selection	4744192
108735894	108735916	X	+	27760321	HT1080	viability	ATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.0923498074142729	[677,528]	[193,259]	0	hSpCas9	negative selection	4744193
108735561	108735583	X	-	27760321	HT29	viability after 7 days	CGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.06956049620428573	[490,382]	[783,528,485]	1	hSpCas9	negative selection	4827654
108735804	108735826	X	-	27760321	HT29	viability after 7 days	GACGAATACTTCGCGATGGTGG	IRS4	ENSG00000133124	-0.32110813199051136	[454,354]	[366,563,314]	-4	hSpCas9	negative selection	4827655
108735894	108735916	X	+	27760321	HT29	viability after 7 days	ATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.1285988132730571	[677,528]	[868,892,398]	-2	hSpCas9	negative selection	4827656
108735561	108735583	X	-	27760321	HT29	viability after 25 days	CGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.20063108874752245	[490,382]	[673,479,558]	2	hSpCas9	negative selection	4911117
108735804	108735826	X	-	27760321	HT29	viability after 25 days	GACGAATACTTCGCGATGGTGG	IRS4	ENSG00000133124	-0.37336168705968253	[454,354]	[239,642,176]	-4	hSpCas9	negative selection	4911118
108735894	108735916	X	+	27760321	HT29	viability after 25 days	ATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.1135320637376096	[677,528]	[549,898,806]	1	hSpCas9	negative selection	4911119
108735561	108735583	X	-	27760321	HT29	viability after 22 days	CGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.19818670477435324	[490,382]	[686,549,497]	2	hSpCas9	negative selection	4994580
108735804	108735826	X	-	27760321	HT29	viability after 22 days	GACGAATACTTCGCGATGGTGG	IRS4	ENSG00000133124	-0.5824197914144421	[454,354]	[412,241,279]	-5	hSpCas9	negative selection	4994581
108735894	108735916	X	+	27760321	HT29	viability after 22 days	ATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.009339582806329516	[677,528]	[584,897,625]	0	hSpCas9	negative selection	4994582
108735561	108735583	X	-	27760321	HT29	viability after 19 days	CGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.17716629090927222	[490,382]	[596,745,362]	1	hSpCas9	negative selection	5078043
108735804	108735826	X	-	27760321	HT29	viability after 19 days	GACGAATACTTCGCGATGGTGG	IRS4	ENSG00000133124	-0.9166749109897097	[454,354]	[227,284,221]	-6	hSpCas9	negative selection	5078044
108735894	108735916	X	+	27760321	HT29	viability after 19 days	ATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.03180938164947722	[677,528]	[651,788,670]	0	hSpCas9	negative selection	5078045
108735561	108735583	X	-	27760321	HT29	viability after 16 days	CGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.31289621825191544	[490,382]	[624,511,688]	3	hSpCas9	negative selection	5161506
108735804	108735826	X	-	27760321	HT29	viability after 16 days	GACGAATACTTCGCGATGGTGG	IRS4	ENSG00000133124	-0.46332276746384593	[454,354]	[388,350,250]	-5	hSpCas9	negative selection	5161507
108735894	108735916	X	+	27760321	HT29	viability after 16 days	ATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.28302632920632737	[677,528]	[409,514,726]	-3	hSpCas9	negative selection	5161508
108735561	108735583	X	-	27760321	HT29	viability after 13 days	CGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.2978876797860183	[490,382]	[815,581,479]	4	hSpCas9	negative selection	5244969
108735804	108735826	X	-	27760321	HT29	viability after 13 days	GACGAATACTTCGCGATGGTGG	IRS4	ENSG00000133124	-0.7364564013653084	[454,354]	[260,268,313]	-6	hSpCas9	negative selection	5244970
108735894	108735916	X	+	27760321	HT29	viability after 13 days	ATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.0019403816178339417	[677,528]	[679,839,589]	0	hSpCas9	negative selection	5244971
108735561	108735583	X	-	27760321	HT29	viability after 10 days	CGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	-0.07553600960603493	[490,382]	[625,504,423]	-1	hSpCas9	negative selection	5328432
108735804	108735826	X	-	27760321	HT29	viability after 10 days	GACGAATACTTCGCGATGGTGG	IRS4	ENSG00000133124	-0.43680493560847633	[454,354]	[512,458,155]	-5	hSpCas9	negative selection	5328433
108735894	108735916	X	+	27760321	HT29	viability after 10 days	ATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.08854384178135966	[677,528]	[840,754,805]	1	hSpCas9	negative selection	5328434
108735561	108735583	X	-	27760321	MOLM13	viability	CGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.46489468435499354	[611,490]	[352,489]	3	hSpCas9	negative selection	5411895
108735804	108735826	X	-	27760321	MOLM13	viability	GACGAATACTTCGCGATGGTGG	IRS4	ENSG00000133124	-0.16896548775661024	[604,454]	[535,31]	-1	hSpCas9	negative selection	5411896
108735894	108735916	X	+	27760321	MOLM13	viability	ATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.23341477676051814	[879,677]	[362,377]	-1	hSpCas9	negative selection	5411897
108735870	108735893	X	+	27661255	K562	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	-0.033385363340816016	[918,874]	[710,691]	-1	dCas9-KRAB	negative selection	5487248
108735807	108735830	X	+	27260156	BXPC3	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.24802795887552553	[894]	[1006,1075,1197,1179]	5	hSpCas9	negative selection	5549764
108735893	108735916	X	+	27260156	BXPC3	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.26450480259758535	[259]	[222,171,231,287]	-5	hSpCas9	negative selection	5549765
108735561	108735584	X	-	27260156	BXPC3	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.15501546486422993	[553]	[494,514,759,857]	3	hSpCas9	negative selection	5549766
108734233	108734256	X	-	27260156	BXPC3	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.11475242003206243	[862]	[762,810,882,886]	-3	hSpCas9	negative selection	5614020
108733499	108733522	X	+	27260156	BXPC3	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.17165306118522394	[234]	[304,230,266,304]	4	hSpCas9	negative selection	5614022
108735807	108735830	X	+	27260156	A673	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.1450372772234264	[894]	[1365,1164,1041,1200]	3	hSpCas9	negative selection	5671015
108735893	108735916	X	+	27260156	A673	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.39990470030288194	[259]	[249,209,237,250]	-7	hSpCas9	negative selection	5671016
108735561	108735584	X	-	27260156	A673	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.14291383613308936	[553]	[812,726,762,636]	3	hSpCas9	negative selection	5671017
108734233	108734256	X	-	27260156	A673	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.2898508560880021	[862]	[805,821,836,923]	-6	hSpCas9	negative selection	5735271
108733499	108733522	X	+	27260156	A673	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	-0.2084106866994606	[234]	[236,192,248,300]	-5	hSpCas9	negative selection	5735273
108735807	108735830	X	+	27260156	A375	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.24351550861481142	[894]	[1327,1369,1356,944]	3	hSpCas9	negative selection	5792266
108735893	108735916	X	+	27260156	A375	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.5767097839536524	[259]	[222,298,220,96]	-6	hSpCas9	negative selection	5792267
108735561	108735584	X	-	27260156	A375	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	-0.12381318143360243	[553]	[639,782,403,574]	-2	hSpCas9	negative selection	5792268
108734233	108734256	X	-	27260156	A375	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	0.04875957623377836	[862]	[1212,916,984,1035]	0	hSpCas9	negative selection	5856522
108733499	108733522	X	+	27260156	A375	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.3379607884490119	[234]	[295,508,417,202]	5	hSpCas9	negative selection	5856524
108735807	108735830	X	+	27260156	COLO741	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.3008899266205872	[894]	[1617,1124,1490]	6	hSpCas9	negative selection	5913517
108735893	108735916	X	+	27260156	COLO741	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.531055678619168	[259]	[225,206,253]	-8	hSpCas9	negative selection	5913518
108735561	108735584	X	-	27260156	COLO741	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.09300762101038859	[553]	[652,695,894]	2	hSpCas9	negative selection	5913519
108734233	108734256	X	-	27260156	COLO741	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.01676528489561202	[862]	[1144,1191,945]	0	hSpCas9	negative selection	5977773
108733499	108733522	X	+	27260156	COLO741	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.21202397485790103	[234]	[527,299,237]	4	hSpCas9	negative selection	5977775
108735807	108735830	X	+	27260156	CAL120	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.15591355621367653	[894]	[1576,1146,1051]	2	hSpCas9	negative selection	6034768
108735893	108735916	X	+	27260156	CAL120	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.5082885318784784	[259]	[120,133,407]	-6	hSpCas9	negative selection	6034769
108735561	108735584	X	-	27260156	CAL120	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.05394684688612647	[553]	[789,715,652]	0	hSpCas9	negative selection	6034770
108734233	108734256	X	-	27260156	CAL120	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.1984100868851052	[862]	[1268,848,742]	-3	hSpCas9	negative selection	6099024
108733499	108733522	X	+	27260156	CAL120	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.7224880605989755	[234]	[569,434,455]	9	hSpCas9	negative selection	6099026
108735807	108735830	X	+	27260156	CADOES1	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.3220950696201116	[894]	[1138,1192,932,891]	5	hSpCas9	negative selection	6156019
108735893	108735916	X	+	27260156	CADOES1	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.10440627917494238	[259]	[357,96,247,194]	-2	hSpCas9	negative selection	6156020
108735561	108735584	X	-	27260156	CADOES1	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	-0.17713284140252666	[553]	[396,452,491,481]	-3	hSpCas9	negative selection	6156021
108734233	108734256	X	-	27260156	CADOES1	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.14798301738708497	[862]	[543,750,726,881]	-3	hSpCas9	negative selection	6220275
108733499	108733522	X	+	27260156	CADOES1	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	-0.029984406416654563	[234]	[161,339,157,195]	0	hSpCas9	negative selection	6220277
108735807	108735830	X	+	27260156	EWS502	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	-0.015499779763027632	[894]	[838,973,898,1053]	0	hSpCas9	negative selection	6277270
108735893	108735916	X	+	27260156	EWS502	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.3417231077668479	[259]	[292,153,156,259]	-5	hSpCas9	negative selection	6277271
108735561	108735584	X	-	27260156	EWS502	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.07594742293292409	[553]	[637,529,651,655]	1	hSpCas9	negative selection	6277272
108734233	108734256	X	-	27260156	EWS502	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.13252744597276056	[862]	[784,906,900,735]	-2	hSpCas9	negative selection	6341526
108733499	108733522	X	+	27260156	EWS502	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	-0.05317211146175471	[234]	[183,402,166,200]	-1	hSpCas9	negative selection	6341528
108735807	108735830	X	+	27260156	EW8	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.052903987855762	[894]	[1089,777,504,713]	1	hSpCas9	negative selection	6398521
108735893	108735916	X	+	27260156	EW8	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.20929632212619764	[259]	[103,243,212,153]	-4	hSpCas9	negative selection	6398522
108735561	108735584	X	-	27260156	EW8	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.1708756968117223	[553]	[748,510,269,556]	3	hSpCas9	negative selection	6398523
108734233	108734256	X	-	27260156	EW8	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.24260240525004184	[862]	[607,537,562,659]	-4	hSpCas9	negative selection	6462777
108733499	108733522	X	+	27260156	EW8	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	-0.004778433198856513	[234]	[201,224,173,161]	0	hSpCas9	negative selection	6462779
108735807	108735830	X	+	27260156	CORL105	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.21496438078588131	[894]	[1303,1086,1194,1279]	4	hSpCas9	negative selection	6519772
108735893	108735916	X	+	27260156	CORL105	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.32811922981027863	[259]	[133,349,292,194]	-6	hSpCas9	negative selection	6519773
108735561	108735584	X	-	27260156	CORL105	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	-0.05655939098404389	[553]	[567,591,675,664]	-1	hSpCas9	negative selection	6519774
108734233	108734256	X	-	27260156	CORL105	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	0.13775822448918817	[862]	[1122,884,1569,944]	2	hSpCas9	negative selection	6584028
108733499	108733522	X	+	27260156	CORL105	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	-0.11389167370626985	[234]	[216,374,225,190]	-2	hSpCas9	negative selection	6584030
108735807	108735830	X	+	27260156	HS294T	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.234163315684491	[894]	[528,291,344,461]	3	hSpCas9	negative selection	6641023
108735893	108735916	X	+	27260156	HS294T	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.6018570337041245	[259]	[54,64,53,96]	-7	hSpCas9	negative selection	6641024
108735561	108735584	X	-	27260156	HS294T	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	-0.005391061664433094	[553]	[176,243,162,282]	0	hSpCas9	negative selection	6641025
108734233	108734256	X	-	27260156	HS294T	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.0026983362915138365	[862]	[304,332,351,345]	0	hSpCas9	negative selection	6705279
108733499	108733522	X	+	27260156	HS294T	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	-0.19413527308161926	[234]	[105,57,79,69]	-3	hSpCas9	negative selection	6705281
108735807	108735830	X	+	27260156	HCC44	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.13121823057664572	[894]	[1252,1094,1060,1025]	2	hSpCas9	negative selection	6762274
108735893	108735916	X	+	27260156	HCC44	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.40933424939016794	[259]	[240,125,324,224]	-6	hSpCas9	negative selection	6762275
108735561	108735584	X	-	27260156	HCC44	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	-0.1910336692701471	[553]	[687,376,643,535]	-3	hSpCas9	negative selection	6762276
108734233	108734256	X	-	27260156	HCC44	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.35818947572363513	[862]	[1210,547,642,690]	-5	hSpCas9	negative selection	6826530
108733499	108733522	X	+	27260156	HCC44	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	-0.07336798954883861	[234]	[290,161,399,198]	-1	hSpCas9	negative selection	6826532
108735807	108735830	X	+	27260156	G402	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.17298753592660832	[894]	[695,1669,1138,1356]	2	hSpCas9	negative selection	6883525
108735893	108735916	X	+	27260156	G402	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.3995579775802831	[259]	[126,1052,256,238]	5	hSpCas9	negative selection	6883526
108735561	108735584	X	-	27260156	G402	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	-0.37330039979465207	[553]	[430,591,458,590]	-5	hSpCas9	negative selection	6883527
108734233	108734256	X	-	27260156	G402	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.3195016973189887	[862]	[1054,962,896,510]	-4	hSpCas9	negative selection	6947781
108733499	108733522	X	+	27260156	G402	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	-0.07323211081103764	[234]	[141,459,159,316]	-1	hSpCas9	negative selection	6947783
108735807	108735830	X	+	27260156	L33	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.31048485114324265	[894]	[1154,449,762,972]	6	hSpCas9	negative selection	7004776
108735893	108735916	X	+	27260156	L33	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.5005993732346885	[259]	[148,87,116,185]	-8	hSpCas9	negative selection	7004777
108735561	108735584	X	-	27260156	L33	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.2545173142017667	[553]	[603,308,433,596]	5	hSpCas9	negative selection	7004778
108734233	108734256	X	-	27260156	L33	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.06119642820912097	[862]	[854,415,465,696]	-1	hSpCas9	negative selection	7069032
108733499	108733522	X	+	27260156	L33	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.0509544506287245	[234]	[237,59,226,228]	1	hSpCas9	negative selection	7069034
108735807	108735830	X	+	27260156	K562	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.19993466011061256	[894]	[703,1366,855,744]	2	hSpCas9	negative selection	7126027
108735893	108735916	X	+	27260156	K562	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.05805050087883201	[259]	[153,131,193,442]	0	hSpCas9	negative selection	7126028
108735561	108735584	X	-	27260156	K562	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	-0.5637927706814443	[553]	[381,343,287,320]	-6	hSpCas9	negative selection	7126029
108734233	108734256	X	-	27260156	K562	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.05370370810549385	[862]	[878,599,927,565]	0	hSpCas9	negative selection	7190283
108733499	108733522	X	+	27260156	K562	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.5939623570549799	[234]	[179,186,642,238]	7	hSpCas9	negative selection	7190285
108735807	108735830	X	+	27260156	HT29	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.4028485240286762	[894]	[1396,1461,1542,1350]	7	hSpCas9	negative selection	7247278
108735893	108735916	X	+	27260156	HT29	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.3651681311057544	[259]	[187,227,295,259]	-6	hSpCas9	negative selection	7247279
108735561	108735584	X	-	27260156	HT29	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.15989742521454056	[553]	[690,1099,654,601]	3	hSpCas9	negative selection	7247280
108734233	108734256	X	-	27260156	HT29	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.18347625403041656	[862]	[1069,896,937,806]	-4	hSpCas9	negative selection	7311534
108733499	108733522	X	+	27260156	HT29	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.07190104597312275	[234]	[270,383,330,226]	1	hSpCas9	negative selection	7311536
108735807	108735830	X	+	27260156	MHHES1	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.2716864298599132	[894]	[1560,1180,1173,1009]	5	hSpCas9	negative selection	7368529
108735893	108735916	X	+	27260156	MHHES1	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.4893646738663193	[259]	[251,197,116,254]	-7	hSpCas9	negative selection	7368530
108735561	108735584	X	-	27260156	MHHES1	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.1769790265693447	[553]	[867,869,454,657]	3	hSpCas9	negative selection	7368531
108734233	108734256	X	-	27260156	MHHES1	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.09728494970829549	[862]	[1276,857,912,662]	-2	hSpCas9	negative selection	7432785
108733499	108733522	X	+	27260156	MHHES1	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.2550702074989222	[234]	[297,396,388,204]	5	hSpCas9	negative selection	7432787
108735807	108735830	X	+	27260156	MEWO	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.19524014416192792	[894]	[935,835,1099]	4	hSpCas9	negative selection	7489780
108735893	108735916	X	+	27260156	MEWO	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.1589687591892508	[259]	[296,193,177]	-3	hSpCas9	negative selection	7489781
108735561	108735584	X	-	27260156	MEWO	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.2349430329952357	[553]	[855,493,527]	5	hSpCas9	negative selection	7489782
108734233	108734256	X	-	27260156	MEWO	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.24444015605547031	[862]	[826,616,628]	-5	hSpCas9	negative selection	7554036
108733499	108733522	X	+	27260156	MEWO	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	-0.27659155652270817	[234]	[230,191,130]	-6	hSpCas9	negative selection	7554038
108735807	108735830	X	+	27260156	LNCAPCLONEFGC	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.387231821349031	[894]	[1067,1072,1149,961]	6	hSpCas9	negative selection	7611031
108735893	108735916	X	+	27260156	LNCAPCLONEFGC	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.7296128344275801	[259]	[141,159,142,121]	-8	hSpCas9	negative selection	7611032
108735561	108735584	X	-	27260156	LNCAPCLONEFGC	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.2646553362412677	[553]	[569,464,771,638]	4	hSpCas9	negative selection	7611033
108734233	108734256	X	-	27260156	LNCAPCLONEFGC	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	0.14573827809551632	[862]	[802,947,948,766]	2	hSpCas9	negative selection	7675287
108733499	108733522	X	+	27260156	LNCAPCLONEFGC	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.5643830995508219	[234]	[223,324,482,252]	8	hSpCas9	negative selection	7675289
108735807	108735830	X	+	27260156	PANC0327	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.5487063960466824	[894]	[1406,952,1338,999]	7	hSpCas9	negative selection	7732282
108735893	108735916	X	+	27260156	PANC0327	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.2526267519523513	[259]	[429,238,279,168]	4	hSpCas9	negative selection	7732283
108735561	108735584	X	-	27260156	PANC0327	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.3200575514180032	[553]	[765,458,738,525]	5	hSpCas9	negative selection	7732284
108734233	108734256	X	-	27260156	PANC0327	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	0.07014403134264413	[862]	[1005,571,605,1080]	1	hSpCas9	negative selection	7796538
108733499	108733522	X	+	27260156	PANC0327	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.3278946606987405	[234]	[178,433,228,176]	5	hSpCas9	negative selection	7796540
108735807	108735830	X	+	27260156	NCIH2009	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.33117099808278805	[894]	[1817,1301,1649]	4	hSpCas9	negative selection	7853533
108735893	108735916	X	+	27260156	NCIH2009	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.8271764524378702	[259]	[230,208,178]	-7	hSpCas9	negative selection	7853534
108735561	108735584	X	-	27260156	NCIH2009	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	-0.1397151678178219	[553]	[931,751,466]	-2	hSpCas9	negative selection	7853535
108734233	108734256	X	-	27260156	NCIH2009	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	0.16111515936310683	[862]	[1648,1115,1340]	2	hSpCas9	negative selection	7917789
108733499	108733522	X	+	27260156	NCIH2009	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.15062612869488312	[234]	[308,243,530]	2	hSpCas9	negative selection	7917791
108735807	108735830	X	+	27260156	NCIH1373	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.5220680829929395	[894]	[970,742,2016,538]	5	hSpCas9	negative selection	7974784
108735893	108735916	X	+	27260156	NCIH1373	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.04237395868429261	[259]	[58,71,731,63]	0	hSpCas9	negative selection	7974785
108735561	108735584	X	-	27260156	NCIH1373	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.013781953609383307	[553]	[638,1068,359,99]	0	hSpCas9	negative selection	7974786
108734233	108734256	X	-	27260156	NCIH1373	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	0.0771415172011145	[862]	[1114,826,1164,262]	0	hSpCas9	negative selection	8039040
108733499	108733522	X	+	27260156	NCIH1373	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	1.1953782366705394	[234]	[1252,354,428,130]	9	hSpCas9	negative selection	8039042
108735807	108735830	X	+	27260156	PATU8902	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.4387140163647586	[894]	[1789,1765,1234,2121]	4	hSpCas9	negative selection	8096035
108735893	108735916	X	+	27260156	PATU8902	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.8330253047279634	[259]	[160,146,149,389]	-7	hSpCas9	negative selection	8096036
108735561	108735584	X	-	27260156	PATU8902	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.46454089527215137	[553]	[1227,690,1144,1174]	5	hSpCas9	negative selection	8096037
108734233	108734256	X	-	27260156	PATU8902	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.33205927187087825	[862]	[1034,889,499,1577]	-3	hSpCas9	negative selection	8160291
108733499	108733522	X	+	27260156	PATU8902	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.6270861910159273	[234]	[743,581,463,198]	6	hSpCas9	negative selection	8160293
108735807	108735830	X	+	27260156	PANC1	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.2814063833535586	[894]	[920,1088,897,857]	4	hSpCas9	negative selection	8217286
108735893	108735916	X	+	27260156	PANC1	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.10414211958031627	[259]	[243,208,264,232]	1	hSpCas9	negative selection	8217287
108735561	108735584	X	-	27260156	PANC1	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.2968562557303924	[553]	[514,837,543,498]	5	hSpCas9	negative selection	8217288
108734233	108734256	X	-	27260156	PANC1	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.05735306466107537	[862]	[860,701,821,485]	-1	hSpCas9	negative selection	8281542
108733499	108733522	X	+	27260156	PANC1	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.3486147440960503	[234]	[310,212,355,151]	5	hSpCas9	negative selection	8281544
108735807	108735830	X	+	27260156	PANC0813	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.35298080598482684	[894]	[1610,1178,1394,1215]	6	hSpCas9	negative selection	8338537
108735893	108735916	X	+	27260156	PANC0813	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.49226205930445643	[259]	[358,178,231,116]	-6	hSpCas9	negative selection	8338538
108735561	108735584	X	-	27260156	PANC0813	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.1346659833073697	[553]	[643,596,1033,583]	2	hSpCas9	negative selection	8338539
108734233	108734256	X	-	27260156	PANC0813	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	0.06288059883652941	[862]	[1197,1135,1151,776]	1	hSpCas9	negative selection	8402793
108733499	108733522	X	+	27260156	PANC0813	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.29340011444298086	[234]	[527,214,305,321]	5	hSpCas9	negative selection	8402795
108735807	108735830	X	+	27260156	RDES	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.3454111462286985	[894]	[1102,1271,1521,1355]	5	hSpCas9	negative selection	8459788
108735893	108735916	X	+	27260156	RDES	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.6234744690396097	[259]	[158,147,241,242]	-8	hSpCas9	negative selection	8459789
108735561	108735584	X	-	27260156	RDES	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.13967501463502466	[553]	[557,641,776,875]	2	hSpCas9	negative selection	8459790
108734233	108734256	X	-	27260156	RDES	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	0.04087381963690484	[862]	[820,877,1252,1193]	0	hSpCas9	negative selection	8524044
108733499	108733522	X	+	27260156	RDES	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.3665301844888178	[234]	[321,342,312,419]	6	hSpCas9	negative selection	8524046
108735807	108735830	X	+	27260156	PC3	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.3011439438497109	[894]	[860,1163,1672,880]	6	hSpCas9	negative selection	8581039
108735893	108735916	X	+	27260156	PC3	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.3010669969935267	[259]	[65,313,184,315]	-6	hSpCas9	negative selection	8581040
108735561	108735584	X	-	27260156	PC3	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.024574462144284243	[553]	[489,462,773,565]	0	hSpCas9	negative selection	8581041
108734233	108734256	X	-	27260156	PC3	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.04399691645971138	[862]	[520,924,1089,955]	-1	hSpCas9	negative selection	8645295
108733499	108733522	X	+	27260156	PC3	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	-0.0906896778656685	[234]	[148,168,370,262]	-2	hSpCas9	negative selection	8645297
108735807	108735830	X	+	27260156	PATU8988T	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.1575198292808052	[894]	[731,918,1236,961]	2	hSpCas9	negative selection	8702290
108735893	108735916	X	+	27260156	PATU8988T	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.04272351413643616	[259]	[219,143,157,462]	0	hSpCas9	negative selection	8702291
108735561	108735584	X	-	27260156	PATU8988T	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.2955430251832296	[553]	[811,549,636,615]	5	hSpCas9	negative selection	8702292
108734233	108734256	X	-	27260156	PATU8988T	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.1947689032144868	[862]	[785,717,631,782]	-3	hSpCas9	negative selection	8766546
108733499	108733522	X	+	27260156	PATU8988T	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.00021096468070358476	[234]	[247,281,269,102]	0	hSpCas9	negative selection	8766548
108735807	108735830	X	+	27260156	T47D	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.33376335458905404	[894]	[1298,1059,1546,1369]	7	hSpCas9	negative selection	8823541
108735893	108735916	X	+	27260156	T47D	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.24270296638701416	[259]	[300,233,241,248]	-5	hSpCas9	negative selection	8823542
108735561	108735584	X	-	27260156	T47D	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.16188714717503597	[553]	[689,716,852,622]	3	hSpCas9	negative selection	8823543
108734233	108734256	X	-	27260156	T47D	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.09218928952942362	[862]	[1031,799,969,983]	-2	hSpCas9	negative selection	8887797
108733499	108733522	X	+	27260156	T47D	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.2414183943763698	[234]	[330,271,294,403]	5	hSpCas9	negative selection	8887799
108735807	108735830	X	+	27260156	SU8686	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.255927797018045	[894]	[1023,665,1309,1337]	4	hSpCas9	negative selection	8944792
108735893	108735916	X	+	27260156	SU8686	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.3721545516019473	[259]	[236,183,227,133]	-6	hSpCas9	negative selection	8944793
108735561	108735584	X	-	27260156	SU8686	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.051110644814723466	[553]	[526,465,575,750]	0	hSpCas9	negative selection	8944794
108734233	108734256	X	-	27260156	SU8686	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.1808368407523585	[862]	[791,687,701,849]	-3	hSpCas9	negative selection	9009048
108733499	108733522	X	+	27260156	SU8686	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.08235604790840334	[234]	[275,176,228,319]	1	hSpCas9	negative selection	9009050
108735807	108735830	X	+	27260156	SKES1	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.31995012762929875	[894]	[1155,1358,1066,922]	6	hSpCas9	negative selection	9066043
108735893	108735916	X	+	27260156	SKES1	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.41384410794503523	[259]	[217,148,262,148]	-7	hSpCas9	negative selection	9066044
108735561	108735584	X	-	27260156	SKES1	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	-0.047691455052884774	[553]	[481,619,526,509]	-1	hSpCas9	negative selection	9066045
108734233	108734256	X	-	27260156	SKES1	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.1759029427725749	[862]	[768,828,522,912]	-4	hSpCas9	negative selection	9130299
108733499	108733522	X	+	27260156	SKES1	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.329631413541134	[234]	[306,366,397,131]	7	hSpCas9	negative selection	9130301
108735807	108735830	X	+	27260156	TOV112D	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.3398371792641782	[894]	[1089,1131,1367,946]	6	hSpCas9	negative selection	9187294
108735893	108735916	X	+	27260156	TOV112D	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.869106724797952	[259]	[97,87,120,242]	-9	hSpCas9	negative selection	9187295
108735561	108735584	X	-	27260156	TOV112D	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.2119500782212583	[553]	[582,880,761,403]	4	hSpCas9	negative selection	9187296
108734233	108734256	X	-	27260156	TOV112D	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	0.10414448719863112	[862]	[987,880,990,849]	2	hSpCas9	negative selection	9251550
108733499	108733522	X	+	27260156	TOV112D	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.6115177624094632	[234]	[537,397,300,228]	9	hSpCas9	negative selection	9251552
108735807	108735830	X	+	27260156	TC71	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.19356741597382177	[894]	[1128,1121,1096,1035]	5	hSpCas9	negative selection	9308545
108735893	108735916	X	+	27260156	TC71	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.6297846993114042	[259]	[237,112,176,191]	-9	hSpCas9	negative selection	9308546
108735561	108735584	X	-	27260156	TC71	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.10113358455577307	[553]	[741,641,518,646]	2	hSpCas9	negative selection	9308547
108734233	108734256	X	-	27260156	TC71	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.2967529075762323	[862]	[697,731,798,784]	-7	hSpCas9	negative selection	9372801
108733499	108733522	X	+	27260156	TC71	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.03904902543010769	[234]	[278,295,228,229]	1	hSpCas9	negative selection	9372803
108735807	108735830	X	+	27260156	TC32	viability	CCATCGCGAAGTATTCGTCTTGG	IRS4	ENSG00000133124	0.18916551383286884	[894]	[941,808,1134,979]	3	hSpCas9	negative selection	9429796
108735893	108735916	X	+	27260156	TC32	viability	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.5067698324187029	[259]	[242,70,171,223]	-7	hSpCas9	negative selection	9429797
108735561	108735584	X	-	27260156	TC32	viability	CCGGCTGTGTCTAACCGACGAGG	IRS4	ENSG00000133124	0.0007124998911770264	[553]	[432,345,927,493]	0	hSpCas9	negative selection	9429798
108734233	108734256	X	-	27260156	TC32	viability	ATGACCCATACGTGCCAATGAGG	IRS4	ENSG00000133124	-0.07954068873319708	[862]	[656,644,957,861]	-1	hSpCas9	negative selection	9494052
108733499	108733522	X	+	27260156	TC32	viability	GCAATTATGCCCCACGAATCTGG	IRS4	ENSG00000133124	0.35469151115197906	[234]	[300,203,347,298]	6	hSpCas9	negative selection	9494054
108732778	108732801	X	+	27869803	HPAFII	viability after 27 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	0.8889414271276439	[85]	[32,125,NaN]	7	hSpCas9	negative selection	9607146
108732859	108732882	X	-	27869803	HPAFII	viability after 27 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	1.4566269658431865	[109]	[203,120,NaN]	9	hSpCas9	negative selection	9607147
108734066	108734089	X	+	27869803	HPAFII	viability after 27 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	-0.6851137034792424	[190]	[50,71,NaN]	-5	hSpCas9	negative selection	9607148
108735427	108735450	X	+	27869803	HPAFII	viability after 27 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.4151121930943773	[844]	[371,775,NaN]	3	hSpCas9	negative selection	9607149
108735783	108735806	X	-	27869803	HPAFII	viability after 27 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	0.6660142270921442	[124]	[184,36,NaN]	5	hSpCas9	negative selection	9607150
108735893	108735916	X	+	27869803	HPAFII	viability after 27 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.2180903902456299	[247]	[98,122,NaN]	-2	hSpCas9	negative selection	9607151
108732778	108732801	X	+	27869803	HPAFII	viability after 15 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	1.1051426029504356	[85]	[323,120,NaN]	9	hSpCas9	negative selection	9689595
108732859	108732882	X	-	27869803	HPAFII	viability after 15 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	0.29480359950199897	[109]	[210,103,NaN]	3	hSpCas9	negative selection	9689596
108734066	108734089	X	+	27869803	HPAFII	viability after 15 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	-0.36906531395662023	[190]	[227,115,NaN]	-4	hSpCas9	negative selection	9689597
108735427	108735450	X	+	27869803	HPAFII	viability after 15 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	-0.17027167394142695	[844]	[782,821,NaN]	-2	hSpCas9	negative selection	9689598
108735783	108735806	X	-	27869803	HPAFII	viability after 15 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	-0.11675499293263192	[124]	[97,139,NaN]	-1	hSpCas9	negative selection	9689599
108735893	108735916	X	+	27869803	HPAFII	viability after 15 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.7932721595471002	[247]	[138,162,NaN]	-7	hSpCas9	negative selection	9689600
108732778	108732801	X	+	27869803	ASPC1	viability after 36 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	0.07790954501069014	[206]	[0,29,164]	0	hSpCas9	negative selection	9772044
108732859	108732882	X	-	27869803	ASPC1	viability after 36 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	-0.41013217687762427	[306]	[7,131,89]	-4	hSpCas9	negative selection	9772045
108734066	108734089	X	+	27869803	ASPC1	viability after 36 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	0.5507299914018452	[484]	[453,204,134]	5	hSpCas9	negative selection	9772046
108735427	108735450	X	+	27869803	ASPC1	viability after 36 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.5215340979520218	[1755]	[867,855,897]	5	hSpCas9	negative selection	9772047
108735783	108735806	X	-	27869803	ASPC1	viability after 36 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	0.30663949999252305	[397]	[98,205,193]	3	hSpCas9	negative selection	9772048
108735893	108735916	X	+	27869803	ASPC1	viability after 36 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.2936965434090979	[534]	[15,298,129]	-3	hSpCas9	negative selection	9772049
108732778	108732801	X	+	27869803	PATU8988S	viability after 35 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	0.8238409456931939	[288]	[219,191,NaN]	8	hSpCas9	negative selection	9854493
108732859	108732882	X	-	27869803	PATU8988S	viability after 35 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	-0.020541925782120996	[285]	[138,87,NaN]	0	hSpCas9	negative selection	9854494
108734066	108734089	X	+	27869803	PATU8988S	viability after 35 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	-0.7104597718514001	[310]	[96,55,NaN]	-6	hSpCas9	negative selection	9854495
108735427	108735450	X	+	27869803	PATU8988S	viability after 35 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.3700788345287891	[1456]	[715,800,NaN]	4	hSpCas9	negative selection	9854496
108735783	108735806	X	-	27869803	PATU8988S	viability after 35 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	0.8232476673227915	[218]	[183,127,NaN]	8	hSpCas9	negative selection	9854497
108735893	108735916	X	+	27869803	PATU8988S	viability after 35 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.08827728944771814	[507]	[171,212,NaN]	-1	hSpCas9	negative selection	9854498
108732778	108732801	X	+	27869803	PATU8988S	viability after 31 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	0.1937778540492855	[288]	[144,114,NaN]	2	hSpCas9	negative selection	9936942
108732859	108732882	X	-	27869803	PATU8988S	viability after 31 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	-0.12412101287528776	[285]	[101,107,NaN]	-1	hSpCas9	negative selection	9936943
108734066	108734089	X	+	27869803	PATU8988S	viability after 31 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	0.03079612996647718	[310]	[149,96,NaN]	0	hSpCas9	negative selection	9936944
108735427	108735450	X	+	27869803	PATU8988S	viability after 31 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.36750816233399575	[1456]	[562,986,NaN]	4	hSpCas9	negative selection	9936945
108735783	108735806	X	-	27869803	PATU8988S	viability after 31 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	0.6673696612125736	[218]	[172,94,NaN]	7	hSpCas9	negative selection	9936946
108735893	108735916	X	+	27869803	PATU8988S	viability after 31 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	0.1045555282438478	[507]	[153,298,NaN]	1	hSpCas9	negative selection	9936947
108732778	108732801	X	+	27869803	HPAFII	viability after 35 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	-0.74417519271805	[85]	[9,43,NaN]	-4	hSpCas9	negative selection	10019391
108732859	108732882	X	-	27869803	HPAFII	viability after 35 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	1.116100466165221	[109]	[123,116,NaN]	7	hSpCas9	negative selection	10019392
108734066	108734089	X	+	27869803	HPAFII	viability after 35 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	0.596162766876585	[190]	[132,160,NaN]	4	hSpCas9	negative selection	10019393
108735427	108735450	X	+	27869803	HPAFII	viability after 35 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.9652957916933482	[844]	[211,1536,NaN]	6	hSpCas9	negative selection	10019394
108735783	108735806	X	-	27869803	HPAFII	viability after 35 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	1.0737288540198202	[124]	[175,84,NaN]	7	hSpCas9	negative selection	10019395
108735893	108735916	X	+	27869803	HPAFII	viability after 35 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.17036425835753055	[247]	[64,163,NaN]	-1	hSpCas9	negative selection	10019396
108732778	108732801	X	+	27869803	HPAFII	viability after 31 days	GGCTCCAGGGTTCGAGCCACCGG	IRS4	ENSG00000133124	0.45648827903466493	[85]	[48,84,NaN]	3	hSpCas9	negative selection	10101840
108732859	108732882	X	-	27869803	HPAFII	viability after 31 days	TTGACTCCGCCTCTGCCCGCTGG	IRS4	ENSG00000133124	1.596699989888427	[109]	[224,144,NaN]	9	hSpCas9	negative selection	10101841
108734066	108734089	X	+	27869803	HPAFII	viability after 31 days	TTTGGAGGACTCGGAGCAGGTGG	IRS4	ENSG00000133124	0.178293155005401	[190]	[138,101,NaN]	1	hSpCas9	negative selection	10101842
108735427	108735450	X	+	27869803	HPAFII	viability after 31 days	CTCTCCCGGACCGATGACAGTGG	IRS4	ENSG00000133124	0.7406747477750939	[844]	[354,1268,NaN]	5	hSpCas9	negative selection	10101843
108735783	108735806	X	-	27869803	HPAFII	viability after 31 days	GGCCGAGAACGAGTCGGAGCAGG	IRS4	ENSG00000133124	0.8780151147300999	[124]	[171,81,NaN]	6	hSpCas9	negative selection	10101844
108735893	108735916	X	+	27869803	HPAFII	viability after 31 days	TATAGGGTGATCACGCGCCGCGG	IRS4	ENSG00000133124	-0.3045728454547334	[247]	[49,180,NaN]	-2	hSpCas9	negative selection	10101845
108735896	108735919	X	+	28162770	P31FUJ	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	1.114000559112013	[91]	[233]	9	hSpCas9	negative selection	10175823
108735618	108735641	X	-	28162770	P31FUJ	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.5609130411008056	[667]	[1157]	6	hSpCas9	negative selection	10175824
108735558	108735581	X	-	28162770	P31FUJ	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.5510937448192367	[247]	[426]	6	hSpCas9	negative selection	10175825
108734891	108734914	X	-	28162770	P31FUJ	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	-0.3043554654394125	[61]	[58]	-3	hSpCas9	negative selection	10175826
108734750	108734773	X	-	28162770	P31FUJ	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-1.8572930693221723	[36]	[11]	-8	hSpCas9	negative selection	10175827
108735870	108735893	X	+	28162770	P31FUJ	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	0.5688163480940809	[143]	[250]	6	hSpCas9	negative selection	10175828
108735807	108735830	X	-	28162770	P31FUJ	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	0.7416215488796052	[312]	[614]	8	hSpCas9	negative selection	10175829
108735738	108735761	X	+	28162770	P31FUJ	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	0.15998248801733744	[146]	[192]	1	hSpCas9	negative selection	10175830
108735896	108735919	X	+	28162770	TF1	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10345189
108735618	108735641	X	-	28162770	TF1	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	NaN	[NaN]	[529]	1	hSpCas9	negative selection	10345190
108735558	108735581	X	-	28162770	TF1	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	NaN	[NaN]	[354]	1	hSpCas9	negative selection	10345191
108734891	108734914	X	-	28162770	TF1	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10345192
108734750	108734773	X	-	28162770	TF1	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10345193
108735870	108735893	X	+	28162770	TF1	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	NaN	[NaN]	[147]	1	hSpCas9	negative selection	10345194
108735807	108735830	X	-	28162770	TF1	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	NaN	[NaN]	[280]	1	hSpCas9	negative selection	10345195
108735738	108735761	X	+	28162770	TF1	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10345196
108735896	108735919	X	+	28162770	SKM1	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	0.657991243097608	[37]	[105]	6	hSpCas9	negative selection	10514555
108735618	108735641	X	-	28162770	SKM1	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.5971285558907213	[131]	[352]	6	hSpCas9	negative selection	10514556
108735558	108735581	X	-	28162770	SKM1	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.258918297361562	[77]	[164]	2	hSpCas9	negative selection	10514557
108734891	108734914	X	-	28162770	SKM1	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	0.11088410611945765	[21]	[41]	1	hSpCas9	negative selection	10514558
108734750	108734773	X	-	28162770	SKM1	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-0.04439411935845339	[20]	[35]	0	hSpCas9	negative selection	10514559
108735870	108735893	X	+	28162770	SKM1	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	1.4999263968653571	[23]	[119]	9	hSpCas9	negative selection	10514560
108735807	108735830	X	-	28162770	SKM1	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	-0.18326794085986864	[78]	[122]	-1	hSpCas9	negative selection	10514561
108735738	108735761	X	+	28162770	SKM1	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	-0.47407839460169865	[21]	[27]	-4	hSpCas9	negative selection	10514562
108735896	108735919	X	+	28162770	SKM1	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	0.657991243097608	[37]	[105]	6	hSpCas9	negative selection	10683921
108735618	108735641	X	-	28162770	SKM1	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.5971285558907213	[131]	[352]	6	hSpCas9	negative selection	10683922
108735558	108735581	X	-	28162770	SKM1	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.258918297361562	[77]	[164]	2	hSpCas9	negative selection	10683923
108734891	108734914	X	-	28162770	SKM1	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	0.11088410611945765	[21]	[41]	1	hSpCas9	negative selection	10683924
108734750	108734773	X	-	28162770	SKM1	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-0.04439411935845339	[20]	[35]	0	hSpCas9	negative selection	10683925
108735870	108735893	X	+	28162770	SKM1	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	1.4999263968653571	[23]	[119]	9	hSpCas9	negative selection	10683926
108735807	108735830	X	-	28162770	SKM1	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	-0.18326794085986864	[78]	[122]	-1	hSpCas9	negative selection	10683927
108735738	108735761	X	+	28162770	SKM1	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	-0.47407839460169865	[21]	[27]	-4	hSpCas9	negative selection	10683928
108735896	108735919	X	+	28162770	PL21	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	-0.5398922827246695	[156]	[46]	-4	hSpCas9	negative selection	10853287
108735618	108735641	X	-	28162770	PL21	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.574535129270818	[377]	[244]	5	hSpCas9	negative selection	10853288
108735558	108735581	X	-	28162770	PL21	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.972333696966508	[177]	[151]	7	hSpCas9	negative selection	10853289
108734891	108734914	X	-	28162770	PL21	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	-1.1217884803980422	[49]	[9]	-6	hSpCas9	negative selection	10853290
108734750	108734773	X	-	28162770	PL21	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	1.2001396144893197	[31]	[31]	8	hSpCas9	negative selection	10853291
108735870	108735893	X	+	28162770	PL21	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	0.40263247838806304	[72]	[41]	3	hSpCas9	negative selection	10853292
108735807	108735830	X	-	28162770	PL21	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	0.6471672280126007	[222]	[151]	5	hSpCas9	negative selection	10853293
108735738	108735761	X	+	28162770	PL21	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	-1.5942762518607858	[110]	[15]	-7	hSpCas9	negative selection	10853294
108735896	108735919	X	+	28162770	P31FUJ	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	1.114000559112013	[91]	[233]	9	hSpCas9	negative selection	11022653
108735618	108735641	X	-	28162770	P31FUJ	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.5609130411008056	[667]	[1157]	6	hSpCas9	negative selection	11022654
108735558	108735581	X	-	28162770	P31FUJ	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.5510937448192367	[247]	[426]	6	hSpCas9	negative selection	11022655
108734891	108734914	X	-	28162770	P31FUJ	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	-0.3043554654394125	[61]	[58]	-3	hSpCas9	negative selection	11022656
108734750	108734773	X	-	28162770	P31FUJ	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-1.8572930693221723	[36]	[11]	-8	hSpCas9	negative selection	11022657
108735870	108735893	X	+	28162770	P31FUJ	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	0.5688163480940809	[143]	[250]	6	hSpCas9	negative selection	11022658
108735807	108735830	X	-	28162770	P31FUJ	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	0.7416215488796052	[312]	[614]	8	hSpCas9	negative selection	11022659
108735738	108735761	X	+	28162770	P31FUJ	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	0.15998248801733744	[146]	[192]	1	hSpCas9	negative selection	11022660
108735896	108735919	X	+	28162770	OCIAML5	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	0.005914424263575135	[47]	[86]	0	hSpCas9	negative selection	11192019
108735618	108735641	X	-	28162770	OCIAML5	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.8617509955335831	[288]	[947]	7	hSpCas9	negative selection	11192020
108735558	108735581	X	-	28162770	OCIAML5	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.9014501995660571	[77]	[262]	7	hSpCas9	negative selection	11192021
108734891	108734914	X	-	28162770	OCIAML5	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	-1.5745325953350882	[32]	[19]	-7	hSpCas9	negative selection	11192022
108734750	108734773	X	-	28162770	OCIAML5	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-0.28378281128947114	[28]	[42]	-2	hSpCas9	negative selection	11192023
108735870	108735893	X	+	28162770	OCIAML5	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	0.4903256265830809	[55]	[141]	4	hSpCas9	negative selection	11192024
108735807	108735830	X	-	28162770	OCIAML5	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	0.47111007022062434	[230]	[577]	4	hSpCas9	negative selection	11192025
108735738	108735761	X	+	28162770	OCIAML5	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	0.6839863293762128	[49]	[144]	6	hSpCas9	negative selection	11192026
108735896	108735919	X	+	28162770	EOL1	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	0.5358506644704712	[198]	[151]	5	hSpCas9	negative selection	11361385
108735618	108735641	X	-	28162770	EOL1	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	-0.3812606579535509	[622]	[251]	-3	hSpCas9	negative selection	11361386
108735558	108735581	X	-	28162770	EOL1	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.46341385770223675	[423]	[307]	4	hSpCas9	negative selection	11361387
108734891	108734914	X	-	28162770	EOL1	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	-0.8515562165026298	[136]	[39]	-5	hSpCas9	negative selection	11361388
108734750	108734773	X	-	28162770	EOL1	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-1.6604147291506217	[119]	[19]	-8	hSpCas9	negative selection	11361389
108735870	108735893	X	+	28162770	EOL1	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	-0.3973803233168278	[119]	[47]	-3	hSpCas9	negative selection	11361390
108735807	108735830	X	-	28162770	EOL1	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	0.5042925630206714	[276]	[206]	4	hSpCas9	negative selection	11361391
108735738	108735761	X	+	28162770	EOL1	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	-0.2576555596502146	[117]	[51]	-2	hSpCas9	negative selection	11361392
108735896	108735919	X	+	28162770	MOLM13	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	1.6725798011475679	[163]	[377]	9	hSpCas9	negative selection	11530751
108735618	108735641	X	-	28162770	MOLM13	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.7780189051136741	[662]	[821]	6	hSpCas9	negative selection	11530752
108735558	108735581	X	-	28162770	MOLM13	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	1.5221421408906342	[273]	[568]	9	hSpCas9	negative selection	11530753
108734891	108734914	X	-	28162770	MOLM13	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	-0.9423945877636304	[100]	[37]	-5	hSpCas9	negative selection	11530754
108734750	108734773	X	-	28162770	MOLM13	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-1.2939508812606564	[77]	[22]	-6	hSpCas9	negative selection	11530755
108735870	108735893	X	+	28162770	MOLM13	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	-0.786683445541019	[135]	[56]	-4	hSpCas9	negative selection	11530756
108735807	108735830	X	-	28162770	MOLM13	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	0.3002894330485105	[464]	[413]	2	hSpCas9	negative selection	11530757
108735738	108735761	X	+	28162770	MOLM13	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	-0.5321106184554212	[105]	[52]	-3	hSpCas9	negative selection	11530758
108735896	108735919	X	+	28162770	HEL	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	1.139414800303558	[145]	[205]	8	hSpCas9	negative selection	11700117
108735618	108735641	X	-	28162770	HEL	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.4372086278512781	[481]	[417]	3	hSpCas9	negative selection	11700118
108735558	108735581	X	-	28162770	HEL	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.4032728973049676	[339]	[287]	3	hSpCas9	negative selection	11700119
108734891	108734914	X	-	28162770	HEL	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	-0.25034596408313137	[103]	[55]	-2	hSpCas9	negative selection	11700120
108734750	108734773	X	-	28162770	HEL	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-1.2931308305799276	[87]	[22]	-6	hSpCas9	negative selection	11700121
108735870	108735893	X	+	28162770	HEL	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	0.3151641739718526	[127]	[101]	2	hSpCas9	negative selection	11700122
108735807	108735830	X	-	28162770	HEL	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	-0.2781325182151036	[336]	[177]	-2	hSpCas9	negative selection	11700123
108735738	108735761	X	+	28162770	HEL	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	0.10740709900380141	[99]	[68]	0	hSpCas9	negative selection	11700124
108735896	108735919	X	+	28162770	MV411	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	1.0129722971457522	[89]	[152]	8	hSpCas9	negative selection	11869483
108735618	108735641	X	-	28162770	MV411	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.48155926470133026	[419]	[493]	4	hSpCas9	negative selection	11869484
108735558	108735581	X	-	28162770	MV411	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.84270505989567	[185]	[280]	7	hSpCas9	negative selection	11869485
108734891	108734914	X	-	28162770	MV411	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	-1.883266140861818	[126]	[28]	-8	hSpCas9	negative selection	11869486
108734750	108734773	X	-	28162770	MV411	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-0.7525624492172245	[33]	[16]	-5	hSpCas9	negative selection	11869487
108735870	108735893	X	+	28162770	MV411	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	1.9611333656261345	[99]	[327]	9	hSpCas9	negative selection	11869488
108735807	108735830	X	-	28162770	MV411	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	0.8014681919520408	[219]	[322]	7	hSpCas9	negative selection	11869489
108735738	108735761	X	+	28162770	MV411	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	0.8046550610210271	[69]	[102]	7	hSpCas9	negative selection	11869490
108735896	108735919	X	+	28162770	MONOMAC1	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	-0.5517017283589157	[77]	[60]	-5	hSpCas9	negative selection	12038849
108735618	108735641	X	-	28162770	MONOMAC1	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.5060517545237098	[292]	[476]	5	hSpCas9	negative selection	12038850
108735558	108735581	X	-	28162770	MONOMAC1	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.870939946756453	[113]	[238]	7	hSpCas9	negative selection	12038851
108734891	108734914	X	-	28162770	MONOMAC1	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	-0.646839764499074	[55]	[40]	-5	hSpCas9	negative selection	12038852
108734750	108734773	X	-	28162770	MONOMAC1	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-0.17104163852660892	[54]	[55]	-1	hSpCas9	negative selection	12038853
108735870	108735893	X	+	28162770	MONOMAC1	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	0.3677477717239719	[47]	[70]	3	hSpCas9	negative selection	12038854
108735807	108735830	X	-	28162770	MONOMAC1	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	1.191528440858099	[109]	[287]	9	hSpCas9	negative selection	12038855
108735738	108735761	X	+	28162770	MONOMAC1	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	0.5179861942259754	[52]	[86]	5	hSpCas9	negative selection	12038856
108735896	108735919	X	+	28162770	OCIAML2	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	0.8002240850509319	[22]	[221]	7	hSpCas9	negative selection	12208215
108735618	108735641	X	-	28162770	OCIAML2	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.4541826783636197	[63]	[485]	4	hSpCas9	negative selection	12208216
108735558	108735581	X	-	28162770	OCIAML2	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	1.377367081312789	[29]	[431]	9	hSpCas9	negative selection	12208217
108734891	108734914	X	-	28162770	OCIAML2	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	-0.7544227912427526	[13]	[45]	-5	hSpCas9	negative selection	12208218
108734750	108734773	X	-	28162770	OCIAML2	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-1.733664231075955	[11]	[19]	-8	hSpCas9	negative selection	12208219
108735870	108735893	X	+	28162770	OCIAML2	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	0.685288318206272	[22]	[204]	6	hSpCas9	negative selection	12208220
108735807	108735830	X	-	28162770	OCIAML2	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	0.4362607703663575	[37]	[284]	4	hSpCas9	negative selection	12208221
108735738	108735761	X	+	28162770	OCIAML2	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	0.11433267547899495	[16]	[101]	1	hSpCas9	negative selection	12208222
108735896	108735919	X	+	28162770	OCIAML3	viability	AGGGTGATCACGCGCCGCGGTGG	IRS4	ENSG00000133124	-0.17897014104531916	[32]	[87]	-1	hSpCas9	negative selection	12377581
108735618	108735641	X	-	28162770	OCIAML3	viability	GCAGGTAATAGTCAAACCCAGGG	IRS4	ENSG00000133124	0.02140865693870664	[124]	[382]	0	hSpCas9	negative selection	12377582
108735558	108735581	X	-	28162770	OCIAML3	viability	GCTGTGTCTAACCGACGAGGAGG	IRS4	ENSG00000133124	0.09006300540991774	[74]	[240]	0	hSpCas9	negative selection	12377583
108734891	108734914	X	-	28162770	OCIAML3	viability	GAAGATCAGGAAGGAAGCGGAGG	IRS4	ENSG00000133124	0.07976412735484883	[20]	[66]	0	hSpCas9	negative selection	12377584
108734750	108734773	X	-	28162770	OCIAML3	viability	GAGGGACAGGGATCCCGAGGTGG	IRS4	ENSG00000133124	-3.0534392589614607	[21]	[7]	-9	hSpCas9	negative selection	12377585
108735870	108735893	X	+	28162770	OCIAML3	viability	GCTGGCTCACGGAAAAGCACTGG	IRS4	ENSG00000133124	0.6987741089036827	[29]	[146]	6	hSpCas9	negative selection	12377586
108735807	108735830	X	-	28162770	OCIAML3	viability	CCAAGACGAATACTTCGCGATGG	IRS4	ENSG00000133124	-0.20459594872081366	[70]	[185]	-2	hSpCas9	negative selection	12377587
108735738	108735761	X	+	28162770	OCIAML3	viability	GCTTGCTCTCGAGGATGAGGCGG	IRS4	ENSG00000133124	-1.857042046157957	[29]	[24]	-8	hSpCas9	negative selection	12377588