Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 9445
• Symbol: ITM2B
• Description: integral membrane protein 2B

DataSource: http://genomecrispr.dkfz.de/#!/results/ITM2B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
48233411	48233434	13	+	26472758	Jiyoye	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.2569327459252607	[90]	[81]	2	hSpCas9	negative selection	79913
48256177	48256200	13	+	26472758	Jiyoye	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	8.240065395670614	[0]	[227]	10	hSpCas9	negative selection	79914
48256237	48256260	13	-	26472758	Jiyoye	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	1.13111429537584	[88]	[146]	7	hSpCas9	negative selection	79915
48256250	48256273	13	-	26472758	Jiyoye	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.5656351964547313	[378]	[422]	4	hSpCas9	negative selection	79916
48233359	48233382	13	-	26472758	Jiyoye	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	-0.3105423280670543	[272]	[165]	-2	hSpCas9	negative selection	79917
48253827	48253850	13	+	26472758	Jiyoye	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	-0.034334329134161456	[109]	[80]	0	hSpCas9	negative selection	79918
48253845	48253868	13	-	26472758	Jiyoye	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	0.29013596031565403	[76]	[70]	2	hSpCas9	negative selection	79919
48258152	48258175	13	-	26472758	Jiyoye	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	-0.87992272921839	[265]	[108]	-6	hSpCas9	negative selection	79920
48233452	48233475	13	-	26472758	Jiyoye	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	0.4403422454410728	[42]	[43]	3	hSpCas9	negative selection	79921
48253811	48253834	13	+	26472758	Jiyoye	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	1.326038618780468	[63]	[120]	7	hSpCas9	negative selection	79922
48233411	48233434	13	+	26472758	KBM7	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.34590463170366503	[531,259]	[125,321]	3	hSpCas9	negative selection	271031
48256177	48256200	13	+	26472758	KBM7	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.5684834916536361	[1187,1359]	[1223,607]	6	hSpCas9	negative selection	271032
48256237	48256260	13	-	26472758	KBM7	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	0.2179023832414148	[455,370]	[274,179]	2	hSpCas9	negative selection	271033
48256250	48256273	13	-	26472758	KBM7	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.11733179875280575	[1667,1127]	[760,649]	1	hSpCas9	negative selection	271034
48233359	48233382	13	-	26472758	KBM7	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	0.19805371502250568	[988,860]	[623,384]	2	hSpCas9	negative selection	271035
48253827	48253850	13	+	26472758	KBM7	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	-0.05395446232489465	[288,155]	[122,75]	0	hSpCas9	negative selection	271036
48253845	48253868	13	-	26472758	KBM7	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	0.9315666810401964	[518,585]	[510,491]	8	hSpCas9	negative selection	271037
48258152	48258175	13	-	26472758	KBM7	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	-0.10941709304102037	[570,654]	[159,368]	-1	hSpCas9	negative selection	271038
48233452	48233475	13	-	26472758	KBM7	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	1.3965011930574316	[130,131]	[113,207]	9	hSpCas9	negative selection	271039
48253811	48253834	13	+	26472758	KBM7	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	-0.359354927785385	[585,425]	[185,180]	-3	hSpCas9	negative selection	271040
48233411	48233434	13	+	26472758	Raji	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.40458454435858504	[152]	[46]	4	hSpCas9	negative selection	462149
48256177	48256200	13	+	26472758	Raji	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.028937935839181028	[487]	[110]	0	hSpCas9	negative selection	462150
48256237	48256260	13	-	26472758	Raji	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	0.3988463495339109	[267]	[81]	4	hSpCas9	negative selection	462151
48256250	48256273	13	-	26472758	Raji	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.5076240327243629	[587]	[193]	5	hSpCas9	negative selection	462152
48233359	48233382	13	-	26472758	Raji	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	0.35203941189253884	[394]	[116]	3	hSpCas9	negative selection	462153
48253827	48253850	13	+	26472758	Raji	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	0.34345089360712383	[179]	[52]	3	hSpCas9	negative selection	462154
48253845	48253868	13	-	26472758	Raji	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	-0.07758534629316298	[240]	[52]	0	hSpCas9	negative selection	462155
48258152	48258175	13	-	26472758	Raji	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	0.5603176424109719	[262]	[89]	5	hSpCas9	negative selection	462156
48233452	48233475	13	-	26472758	Raji	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	0.2678482075668456	[67]	[18]	2	hSpCas9	negative selection	462157
48253811	48253834	13	+	26472758	Raji	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	0.5944322795678314	[253]	[88]	5	hSpCas9	negative selection	462158
48233411	48233434	13	+	26472758	K562	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.849615712127657	[235]	[358]	7	hSpCas9	negative selection	653267
48256177	48256200	13	+	26472758	K562	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	1.2238790893575642	[954]	[1882]	9	hSpCas9	negative selection	653268
48256237	48256260	13	-	26472758	K562	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	-0.9814626797498809	[413]	[176]	-5	hSpCas9	negative selection	653269
48256250	48256273	13	-	26472758	K562	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.5210887336455077	[1210]	[1466]	4	hSpCas9	negative selection	653270
48233359	48233382	13	-	26472758	K562	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	0.5059588868199102	[643]	[771]	4	hSpCas9	negative selection	653271
48253827	48253850	13	+	26472758	K562	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	1.17481326018058	[137]	[262]	8	hSpCas9	negative selection	653272
48253845	48253868	13	-	26472758	K562	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	0.8662808111991325	[385]	[593]	7	hSpCas9	negative selection	653273
48258152	48258175	13	-	26472758	K562	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	0.6069888070511553	[419]	[539]	5	hSpCas9	negative selection	653274
48233452	48233475	13	-	26472758	K562	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	0.28564139039295977	[137]	[141]	2	hSpCas9	negative selection	653275
48253811	48253834	13	+	26472758	K562	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	0.835355129432236	[240]	[362]	7	hSpCas9	negative selection	653276
48233378	48233401	13	+	26627737	DLD1	viability	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	-0.02756458314010868	[420]	[149,110,125]	0	hSpCas9	negative selection	786995
48233406	48233429	13	+	26627737	DLD1	viability	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.07102380989225265	[723]	[236,271,209]	0	hSpCas9	negative selection	786996
48233458	48233481	13	-	26627737	DLD1	viability	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.33275292438630844	[1032]	[289,269,215]	-3	hSpCas9	negative selection	786997
48256252	48256275	13	-	26627737	DLD1	viability	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	0.35280473239869536	[166]	[83,29,81]	3	hSpCas9	negative selection	786998
48233378	48233401	13	+	26627737	GBM cells	viability after 5 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	0.5928107471600059	[135]	[115,103]	8	hSpCas9	negative selection	869310
48233406	48233429	13	+	26627737	GBM cells	viability after 5 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.29785287059988563	[382]	[271,232]	4	hSpCas9	negative selection	869311
48233458	48233481	13	-	26627737	GBM cells	viability after 5 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.1519704695239033	[265]	[160,155]	2	hSpCas9	negative selection	869312
48256252	48256275	13	-	26627737	GBM cells	viability after 5 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	0.3612570889428859	[89]	[60,62]	5	hSpCas9	negative selection	869313
48233378	48233401	13	+	26627737	GBM cells	viability after 13 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	0.44474168581812407	[135]	[143,64]	5	hSpCas9	negative selection	951625
48233406	48233429	13	+	26627737	GBM cells	viability after 13 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.351231375758398	[382]	[306,230]	4	hSpCas9	negative selection	951626
48233458	48233481	13	-	26627737	GBM cells	viability after 13 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.12085101102207148	[265]	[140,125]	-1	hSpCas9	negative selection	951627
48256252	48256275	13	-	26627737	GBM cells	viability after 13 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	0.6012794043011253	[89]	[99,52]	7	hSpCas9	negative selection	951628
48233378	48233401	13	+	26627737	GBM cells	viability after 21 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	-1.7824567157531197	[135]	[21,20]	-8	hSpCas9	negative selection	1033940
48233406	48233429	13	+	26627737	GBM cells	viability after 21 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.274339354630578	[382]	[247,254]	3	hSpCas9	negative selection	1033941
48233458	48233481	13	-	26627737	GBM cells	viability after 21 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.8433674386829719	[265]	[275,243]	8	hSpCas9	negative selection	1033942
48256252	48256275	13	-	26627737	GBM cells	viability after 21 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	-0.1723660600143493	[89]	[45,40]	-1	hSpCas9	negative selection	1033943
48233378	48233401	13	+	26627737	RPE1	viability after 9 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	-0.7698757852056493	[583]	[63,162]	-5	hSpCas9	negative selection	1116255
48233406	48233429	13	+	26627737	RPE1	viability after 9 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.3253710392211395	[1290]	[560,435]	2	hSpCas9	negative selection	1116256
48233458	48233481	13	-	26627737	RPE1	viability after 9 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.657410304985456	[1130]	[127,348]	-5	hSpCas9	negative selection	1116257
48256252	48256275	13	-	26627737	RPE1	viability after 9 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	-1.66545296649119	[413]	[32,50]	-8	hSpCas9	negative selection	1116258
48233378	48233401	13	+	26627737	RPE1	viability after 12 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	-0.029605706707859503	[583]	[75,235]	0	hSpCas9	negative selection	1198570
48233406	48233429	13	+	26627737	RPE1	viability after 12 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.5168652430187359	[1290]	[454,539]	3	hSpCas9	negative selection	1198571
48233458	48233481	13	-	26627737	RPE1	viability after 12 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.3158588875740953	[1130]	[128,365]	-2	hSpCas9	negative selection	1198572
48256252	48256275	13	-	26627737	RPE1	viability after 12 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	-1.221026175409739	[413]	[37,57]	-7	hSpCas9	negative selection	1198573
48233378	48233401	13	+	26627737	RPE1	viability after 15 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	-0.8876921156251467	[583]	[44,131]	-5	hSpCas9	negative selection	1280885
48233406	48233429	13	+	26627737	RPE1	viability after 15 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	-0.13931477540907933	[1290]	[298,362]	-1	hSpCas9	negative selection	1280886
48233458	48233481	13	-	26627737	RPE1	viability after 15 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.4021777674284748	[1130]	[123,355]	-3	hSpCas9	negative selection	1280887
48256252	48256275	13	-	26627737	RPE1	viability after 15 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	-1.9622386355161536	[413]	[26,32]	-8	hSpCas9	negative selection	1280888
48233378	48233401	13	+	26627737	RPE1	viability after 18 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	-1.050250889413031	[583]	[49,103]	-6	hSpCas9	negative selection	1363200
48233406	48233429	13	+	26627737	RPE1	viability after 18 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	-0.06301081993040203	[1290]	[362,301]	0	hSpCas9	negative selection	1363201
48233458	48233481	13	-	26627737	RPE1	viability after 18 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.38680228938117556	[1130]	[187,281]	-2	hSpCas9	negative selection	1363202
48256252	48256275	13	-	26627737	RPE1	viability after 18 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	-1.8573627790646356	[413]	[25,35]	-8	hSpCas9	negative selection	1363203
48233378	48233401	13	+	26627737	HeLa	viability after 8 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	-0.27193693436556776	[128]	[34,85,17]	-3	hSpCas9	negative selection	1445515
48233406	48233429	13	+	26627737	HeLa	viability after 8 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.28971302040561836	[522]	[348,205,293]	2	hSpCas9	negative selection	1445516
48233458	48233481	13	-	26627737	HeLa	viability after 8 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.5562131291991743	[424]	[238,437,140]	5	hSpCas9	negative selection	1445517
48256252	48256275	13	-	26627737	HeLa	viability after 8 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	3.624160657054893	[7]	[91,10,36]	9	hSpCas9	negative selection	1445518
48233378	48233401	13	+	26627737	HeLa	viability after 12 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	1.8349841281356607	[128]	[331,111,138]	9	hSpCas9	negative selection	1527830
48233406	48233429	13	+	26627737	HeLa	viability after 12 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.49669150725024974	[522]	[438,302,176]	4	hSpCas9	negative selection	1527831
48233458	48233481	13	-	26627737	HeLa	viability after 12 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.3758070868667315	[424]	[221,298,154]	3	hSpCas9	negative selection	1527832
48256252	48256275	13	-	26627737	HeLa	viability after 12 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	3.939528408089487	[7]	[9,78,58]	9	hSpCas9	negative selection	1527833
48233378	48233401	13	+	26627737	HeLa	viability after 15 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	1.368510974891887	[128]	[21,120,275]	8	hSpCas9	negative selection	1610145
48233406	48233429	13	+	26627737	HeLa	viability after 15 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.2519919806294067	[522]	[296,270,186]	2	hSpCas9	negative selection	1610146
48233458	48233481	13	-	26627737	HeLa	viability after 15 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.9140669147132326	[424]	[346,374,249]	7	hSpCas9	negative selection	1610147
48256252	48256275	13	-	26627737	HeLa	viability after 15 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	3.9723399249590594	[7]	[90,32,26]	9	hSpCas9	negative selection	1610148
48233378	48233401	13	+	26627737	HeLa	viability after 18 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	1.3678864374309279	[128]	[13,100,275]	8	hSpCas9	negative selection	1692460
48233406	48233429	13	+	26627737	HeLa	viability after 18 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.24203142802380245	[522]	[200,217,186]	2	hSpCas9	negative selection	1692461
48233458	48233481	13	-	26627737	HeLa	viability after 18 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.956581623367086	[424]	[232,333,249]	7	hSpCas9	negative selection	1692462
48256252	48256275	13	-	26627737	HeLa	viability after 18 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	3.9052540330693875	[7]	[59,22,26]	9	hSpCas9	negative selection	1692463
48233378	48233401	13	+	26627737	HCT116	viability after 6 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	1.2562351961368887	[377]	[188,115]	6	hSpCas9	negative selection	1774775
48233406	48233429	13	+	26627737	HCT116	viability after 6 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	-2.5592181379304346	[1335]	[92,3]	-8	hSpCas9	negative selection	1774776
48233458	48233481	13	-	26627737	HCT116	viability after 6 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.09442077730331544	[706]	[145,80]	0	hSpCas9	negative selection	1774777
48256252	48256275	13	-	26627737	HCT116	viability after 6 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	0.08790546229792717	[211]	[37,33]	0	hSpCas9	negative selection	1774778
48233378	48233401	13	+	26627737	HCT116	viability after 8 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	-1.3777774605102244	[403]	[77,104,73]	-9	hSpCas9	negative selection	1857090
48233406	48233429	13	+	26627737	HCT116	viability after 8 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.40968049528749256	[384]	[260,296,286]	4	hSpCas9	negative selection	1857091
48233458	48233481	13	-	26627737	HCT116	viability after 8 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.3556523145767933	[382]	[204,82,206]	-4	hSpCas9	negative selection	1857092
48256252	48256275	13	-	26627737	HCT116	viability after 8 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	1.9722667738280006	[41]	[81,76,112]	9	hSpCas9	negative selection	1857093
48233378	48233401	13	+	26627737	HCT116	viability after 9 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	0.568703844666767	[377]	[142,154]	4	hSpCas9	negative selection	1939405
48233406	48233429	13	+	26627737	HCT116	viability after 9 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	-0.6164261790130757	[1335]	[330,154]	-4	hSpCas9	negative selection	1939406
48233458	48233481	13	-	26627737	HCT116	viability after 9 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.06897694125455753	[706]	[378,54]	0	hSpCas9	negative selection	1939407
48256252	48256275	13	-	26627737	HCT116	viability after 9 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	0.9721876063289759	[211]	[100,118]	6	hSpCas9	negative selection	1939408
48233378	48233401	13	+	26627737	HCT116	viability after 12 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	-0.7349357789403406	[403]	[188,114,72]	-7	hSpCas9	negative selection	2021720
48233406	48233429	13	+	26627737	HCT116	viability after 12 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.20788309483209594	[384]	[204,250,247]	2	hSpCas9	negative selection	2021721
48233458	48233481	13	-	26627737	HCT116	viability after 12 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.12293876851510177	[382]	[198,164,293]	1	hSpCas9	negative selection	2021722
48256252	48256275	13	-	26627737	HCT116	viability after 12 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	1.7202758354328866	[41]	[38,107,74]	9	hSpCas9	negative selection	2021723
48233378	48233401	13	+	26627737	HCT116	viability after 15 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	-1.3484589168394825	[403]	[196,61,27]	-8	hSpCas9	negative selection	2104035
48233406	48233429	13	+	26627737	HCT116	viability after 15 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.6038387205152334	[384]	[310,189,501]	5	hSpCas9	negative selection	2104036
48233458	48233481	13	-	26627737	HCT116	viability after 15 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.548184342877345	[382]	[159,188,103]	-5	hSpCas9	negative selection	2104037
48256252	48256275	13	-	26627737	HCT116	viability after 15 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	2.03405558405547	[41]	[65,96,128]	9	hSpCas9	negative selection	2104038
48233378	48233401	13	+	26627737	HCT116	viability after 18 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	-0.5915844932062561	[403]	[195,100,91]	-5	hSpCas9	negative selection	2186350
48233406	48233429	13	+	26627737	HCT116	viability after 18 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.6903139813137387	[384]	[314,208,386]	5	hSpCas9	negative selection	2186351
48233458	48233481	13	-	26627737	HCT116	viability after 18 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.24853630283980868	[382]	[119,166,180]	-2	hSpCas9	negative selection	2186352
48256252	48256275	13	-	26627737	HCT116	viability after 18 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	1.8036506894997544	[41]	[67,51,94]	9	hSpCas9	negative selection	2186353
48233348	48233371	13	+	24336569	HL60	viability	CCCAGGCCGCGCCATGGTGAAGG	ITM2B	ENSG00000136156	0.9431979536053731	[289]	[1179]	7	hSpCas9	negative selection	2272411
48233359	48233382	13	-	24336569	HL60	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	1.3631632855591622	[373]	[2035]	8	hSpCas9	negative selection	2272412
48233369	48233392	13	+	24336569	HL60	viability	GGTGACGTTCAACTCCGCTCTGG	ITM2B	ENSG00000136156	0.7154616552344348	[237]	[826]	6	hSpCas9	negative selection	2272413
48233378	48233401	13	+	24336569	HL60	viability	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	-0.5194020020178188	[253]	[374]	-5	hSpCas9	negative selection	2272414
48233383	48233406	13	-	24336569	HL60	viability	GGCCTCCTTCTGGGCCAGAGCGG	ITM2B	ENSG00000136156	-0.41021346137227255	[794]	[1265]	-4	hSpCas9	negative selection	2272415
48233404	48233427	13	-	24336569	HL60	viability	GCTCTTGGGCTCGTCCTTCTTGG	ITM2B	ENSG00000136156	2.5921232994327243	[145]	[1862]	9	hSpCas9	negative selection	2272416
48233411	48233434	13	+	24336569	HL60	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.33864438819736964	[496]	[1329]	3	hSpCas9	negative selection	2272417
48233418	48233441	13	-	24336569	HL60	viability	AGCGCCTCCTCGCCGCTCTTGGG	ITM2B	ENSG00000136156	-0.3586538807509744	[634]	[1047]	-3	hSpCas9	negative selection	2272418
48233451	48233474	13	-	24336569	HL60	viability	CAGTCCACCGCGACGGCGTCGGG	ITM2B	ENSG00000136156	-0.5542170977640271	[33]	[48]	-5	hSpCas9	negative selection	2272419
48233456	48233479	13	+	24336569	HL60	viability	CGCCGTCGCGGTGGACTGCAAGG	ITM2B	ENSG00000136156	5.240463994258466	[3]	[319]	9	hSpCas9	negative selection	2272420
48233348	48233371	13	+	24336569	KBM7	viability	CCCAGGCCGCGCCATGGTGAAGG	ITM2B	ENSG00000136156	0.5606647975460259	[348]	[1403]	5	hSpCas9	negative selection	2339588
48233359	48233382	13	-	24336569	KBM7	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	-0.6908503475612463	[608]	[1028]	-5	hSpCas9	negative selection	2339589
48233369	48233392	13	+	24336569	KBM7	viability	GGTGACGTTCAACTCCGCTCTGG	ITM2B	ENSG00000136156	-0.7175552118015232	[374]	[621]	-5	hSpCas9	negative selection	2339590
48233378	48233401	13	+	24336569	KBM7	viability	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	0.05976240704979985	[209]	[596]	0	hSpCas9	negative selection	2339591
48233383	48233406	13	-	24336569	KBM7	viability	GGCCTCCTTCTGGGCCAGAGCGG	ITM2B	ENSG00000136156	0.15098790172895502	[386]	[1171]	1	hSpCas9	negative selection	2339592
48233404	48233427	13	-	24336569	KBM7	viability	GCTCTTGGGCTCGTCCTTCTTGG	ITM2B	ENSG00000136156	1.050552346299094	[213]	[1208]	8	hSpCas9	negative selection	2339593
48233411	48233434	13	+	24336569	KBM7	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.0951061258259216	[680]	[1983]	0	hSpCas9	negative selection	2339594
48233418	48233441	13	-	24336569	KBM7	viability	AGCGCCTCCTCGCCGCTCTTGGG	ITM2B	ENSG00000136156	0.45574478403944363	[674]	[2524]	4	hSpCas9	negative selection	2339595
48233451	48233474	13	-	24336569	KBM7	viability	CAGTCCACCGCGACGGCGTCGGG	ITM2B	ENSG00000136156	1.060762022569361	[28]	[164]	8	hSpCas9	negative selection	2339596
48233456	48233479	13	+	24336569	KBM7	viability	CGCCGTCGCGGTGGACTGCAAGG	ITM2B	ENSG00000136156	0.29823731519958896	[64]	[217]	2	hSpCas9	negative selection	2339597
48233407	48233430	13	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.1922404359021062	[2,2]	[1,3]	4	hSpCas9	positive selection	2996238
48233458	48233481	13	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.1299288572871759	[3,2]	[3,2]	2	hSpCas9	positive selection	2996239
48233359	48233382	13	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	-0.2841061007047017	[2,3]	[2,1]	-4	hSpCas9	positive selection	2996240
48256250	48256273	13	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.03844175435355224	[1,1]	[0,1]	0	hSpCas9	positive selection	2996241
48233407	48233430	13	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.46456801886699584	[2,2]	[2,2]	7	hSpCas9	positive selection	3064096
48233458	48233481	13	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.8046355023079375	[3,3]	[2,0]	-9	hSpCas9	positive selection	3064097
48233359	48233382	13	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	-0.025653262734882998	[2,2]	[3,0]	0	hSpCas9	positive selection	3064098
48256250	48256273	13	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.9333212962175363	[1,1]	[4,0]	9	hSpCas9	positive selection	3064099
48253868	48253891		+	24336571	A375	resistance to PLX after 7 days	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	-0.08946076791952573	[15,10]	[10,12]	-3	hSpCas9	positive selection	3121861
48258889	48258912		+	24336571	A375	resistance to PLX after 7 days	TTATCGACTGTGTCATGACAAGG	ITM2B	ENSG00000136156	-0.3401855494956654	[11,10]	[8,8]	-8	hSpCas9	positive selection	3121862
48253868	48253891		+	24336571	A375	resistance to PLX after 14 days	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	-0.38696000695290744	[25,13]	[5,6]	-4	hSpCas9	positive selection	3179654
48258889	48258912		+	24336571	A375	resistance to PLX after 14 days	TTATCGACTGTGTCATGACAAGG	ITM2B	ENSG00000136156	0.6486861100409507	[7,7]	[5,5]	6	hSpCas9	positive selection	3179655
48253868	48253891		+	24336571	A375	viability after 7 days	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.8728778307116285	[6]	[15,10]	9	hSpCas9	negative selection	3237447
48258889	48258912		+	24336571	A375	viability after 7 days	TTATCGACTGTGTCATGACAAGG	ITM2B	ENSG00000136156	0.02853304665334125	[11]	[11,10]	0	hSpCas9	negative selection	3237448
48253868	48253891		+	24336571	A375	viability after 14 days	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	1.4647677465948474	[6]	[25,13]	9	hSpCas9	negative selection	3295240
48258889	48258912		+	24336571	A375	viability after 14 days	TTATCGACTGTGTCATGACAAGG	ITM2B	ENSG00000136156	-0.3965517177455098	[11]	[7,7]	-5	hSpCas9	negative selection	3295241
48258134	48258157	13	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	-1.1263780810282171	[333,333]	[0,0]	-7	hSpCas9	positive selection	3374841
48258194	48258217	13	+	27383988	293T	resistance to West Nile virus (flavivirus)	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	-0.6968700989410402	[247,247]	[0,0]	-5	hSpCas9	positive selection	3374842
48253811	48253834	13	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	-1.7026757206222456	[497,497]	[0,0]	-9	hSpCas9	positive selection	3374843
48233406	48233429	13	+	26780180	HT29	viability (Avana library 4 designs)	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	1.26858759710993	[]	[]	5	hSpCas9	negative selection	3433634
48233458	48233481	13	-	26780180	HT29	viability (Avana library 4 designs)	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	2.15494767301785	[]	[]	7	hSpCas9	negative selection	3433635
48233359	48233382	13	-	26780180	HT29	viability (Avana library 4 designs)	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	1.10024833019996	[]	[]	4	hSpCas9	negative selection	3433636
48256250	48256273	13	-	26780180	HT29	viability (Avana library 4 designs)	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	1.53830937497732	[]	[]	6	hSpCas9	negative selection	3433637
48233359	48233382	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	-2.93227879196844	[]	[]	-4	hSpCas9	negative selection	3520340
48256250	48256273	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	2.71396161407455	[]	[]	4	hSpCas9	negative selection	3520341
48233406	48233429	13	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	5.56313631418208	[]	[]	8	hSpCas9	negative selection	3520342
48233458	48233481	13	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	4.4726867331614	[]	[]	7	hSpCas9	negative selection	3520343
48253883	48253906	13	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTGCAGGTGTTATTCTAGGAGG	ITM2B	ENSG00000136156	3.38859879432772	[]	[]	5	hSpCas9	negative selection	3520344
48233411	48233434	13	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	6.00022505460066	[]	[]	9	hSpCas9	negative selection	3520345
48233359	48233382	13	-	26780180	A375	viability (Avana lentiGuide)	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	3.4277924792387	[]	[]	3	hSpCas9	negative selection	3628999
48256250	48256273	13	-	26780180	A375	viability (Avana lentiGuide)	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	-1.93888657375791	[]	[]	-3	hSpCas9	negative selection	3629000
48233406	48233429	13	+	26780180	A375	viability (Avana lentiGuide)	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	7.05377470853251	[]	[]	5	hSpCas9	negative selection	3629001
48233458	48233481	13	-	26780180	A375	viability (Avana lentiGuide)	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.619769238868044	[]	[]	-1	hSpCas9	negative selection	3629002
48253883	48253906	13	+	26780180	A375	viability (Avana lentiGuide)	CTTGCAGGTGTTATTCTAGGAGG	ITM2B	ENSG00000136156	-3.84153765410321	[]	[]	-6	hSpCas9	negative selection	3629003
48233411	48233434	13	+	26780180	A375	viability (Avana lentiGuide)	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	2.24731199729432	[]	[]	2	hSpCas9	negative selection	3629004
48233359	48233382	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	-0.39625557345905854	[5]	[3,3]	-5	hSpCas9	positive selection	3737658
48256250	48256273	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.1569200552396336	[4]	[5,3]	4	hSpCas9	positive selection	3737659
48233406	48233429	13	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	-0.1977577244730526	[4]	[5,2]	-3	hSpCas9	positive selection	3737660
48233458	48233481	13	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.2527671782791627	[5]	[6,5]	7	hSpCas9	positive selection	3737661
48253883	48253906	13	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTGCAGGTGTTATTCTAGGAGG	ITM2B	ENSG00000136156	0.1375381669554656	[5]	[5,5]	3	hSpCas9	positive selection	3737662
48233411	48233434	13	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.3536568427022741	[4]	[6,5]	9	hSpCas9	positive selection	3737663
48233359	48233382	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	-0.14010664565202796	[5]	[3,4]	-2	hSpCas9	positive selection	3846265
48256250	48256273	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	-0.6163042266471954	[3]	[2,0]	-7	hSpCas9	positive selection	3846266
48233406	48233429	13	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	-0.011198938716971363	[4]	[4,3]	0	hSpCas9	positive selection	3846267
48233458	48233481	13	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.008419454329250167	[5]	[3,5]	0	hSpCas9	positive selection	3846268
48253883	48253906	13	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTGCAGGTGTTATTCTAGGAGG	ITM2B	ENSG00000136156	0.3552824872971276	[5]	[5,6]	9	hSpCas9	positive selection	3846269
48233411	48233434	13	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.16672763835242055	[5]	[4,5]	4	hSpCas9	positive selection	3846270
48258134	48258157	13	+	26780180	A375	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	1.08391267516788	[]	[]	5	hSpCas9	negative selection	3952292
48253811	48253834	13	-	26780180	A375	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	1.17835282317613	[]	[]	6	hSpCas9	negative selection	3952293
48256177	48256200	13	-	26780180	A375	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	1.65626093268613	[]	[]	8	hSpCas9	negative selection	3952294
48256177	48256200	13	+	26780180	A375	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.88496965787024	[]	[]	4	hSpCas9	negative selection	3952295
48253868	48253891	13	+	26780180	A375	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	1.16367181883164	[]	[]	6	hSpCas9	negative selection	3952296
48258194	48258217	13	+	26780180	A375	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.691582375160623	[]	[]	2	hSpCas9	negative selection	3952297
48258134	48258157	13	+	26780180	HT29	viability (GeCKOv2 library)	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.938128376876873	[]	[]	4	hSpCas9	negative selection	4060258
48253811	48253834	13	-	26780180	HT29	viability (GeCKOv2 library)	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	1.3605839672718	[]	[]	7	hSpCas9	negative selection	4060259
48256177	48256200	13	-	26780180	HT29	viability (GeCKOv2 library)	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	1.4556256556927	[]	[]	7	hSpCas9	negative selection	4060260
48256177	48256200	13	+	26780180	HT29	viability (GeCKOv2 library)	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.534468425898941	[]	[]	1	hSpCas9	negative selection	4060261
48253868	48253891	13	+	26780180	HT29	viability (GeCKOv2 library)	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	1.00139224886604	[]	[]	4	hSpCas9	negative selection	4060262
48258194	48258217	13	+	26780180	HT29	viability (GeCKOv2 library)	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.822540475956112	[]	[]	3	hSpCas9	negative selection	4060263
48253868	48253891	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.11821797879312793	[3]	[2,2]	3	hSpCas9	positive selection	4145585
48258889	48258912	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTATCGACTGTGTCATGACAAGG	ITM2B	ENSG00000136156	0.16828320277487327	[3]	[2,2]	4	hSpCas9	positive selection	4145586
48253868	48253891	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.13851665200573537	[2]	[1,2,0,0]	1	hSpCas9	positive selection	4209607
48258889	48258912	13	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTATCGACTGTGTCATGACAAGG	ITM2B	ENSG00000136156	0.20428124412600557	[3]	[3,2,1,0]	1	hSpCas9	positive selection	4209608
48256177	48256200	13	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.05173672944521418	[3]	[3,1]	-1	hSpCas9	positive selection	4277511
48253868	48253891	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.3109939993645216	[2]	[3,1]	6	hSpCas9	positive selection	4277512
48256177	48256200	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.2530206500923424	[3]	[3,3]	5	hSpCas9	positive selection	4277513
48258134	48258157	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	-0.2613948681696838	[3]	[3,0]	-5	hSpCas9	positive selection	4341766
48258194	48258217	13	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.022924133638821814	[3]	[3,1]	0	hSpCas9	positive selection	4341767
48253811	48253834	13	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	-0.31397146222199185	[4]	[3,1]	-6	hSpCas9	positive selection	4341768
48233445	48233467	13	+	27760321	OCIAML3	viability	ATCCCCCCCGACGCCGTCGCGG	ITM2B	ENSG00000136156	-1.1109178075551092	[900,733]	[287,302]	-7	hSpCas9	negative selection	4410651
48256177	48256199	13	-	27760321	OCIAML3	viability	CACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.36787729108665496	[495,347]	[225,287]	-4	hSpCas9	negative selection	4410652
48256327	48256349	13	-	27760321	OCIAML3	viability	TATCTGCAAACTCTGGGACAGG	ITM2B	ENSG00000136156	0.25368380437972177	[566,506]	[460,550]	3	hSpCas9	negative selection	4410653
48258135	48258157	13	+	27760321	OCIAML3	viability	GCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.1112818940909337	[103,81]	[61,98]	1	hSpCas9	negative selection	4410654
48258198	48258220	13	-	27760321	OCIAML3	viability	ACTCCAGTAGGTTTCTGGGTGG	ITM2B	ENSG00000136156	0.2548877900799101	[584,460]	[355,652]	3	hSpCas9	negative selection	4410655
48233445	48233467	13	+	27760321	OCIAML2	viability	ATCCCCCCCGACGCCGTCGCGG	ITM2B	ENSG00000136156	-1.1098451878745237	[900,733]	[262,359]	-8	hSpCas9	negative selection	4494114
48256177	48256199	13	-	27760321	OCIAML2	viability	CACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.35280573836967644	[495,347]	[212,331]	-4	hSpCas9	negative selection	4494115
48256327	48256349	13	-	27760321	OCIAML2	viability	TATCTGCAAACTCTGGGACAGG	ITM2B	ENSG00000136156	-0.13357848326192986	[566,506]	[366,432]	-2	hSpCas9	negative selection	4494116
48258135	48258157	13	+	27760321	OCIAML2	viability	GCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	1.6487372408595604	[103,81]	[198,280]	9	hSpCas9	negative selection	4494117
48258198	48258220	13	-	27760321	OCIAML2	viability	ACTCCAGTAGGTTTCTGGGTGG	ITM2B	ENSG00000136156	-0.33797358828842194	[584,460]	[332,331]	-4	hSpCas9	negative selection	4494118
48233445	48233467	13	+	27760321	MV411	viability	ATCCCCCCCGACGCCGTCGCGG	ITM2B	ENSG00000136156	-1.8649979572108832	[900,733]	[76,252]	-8	hSpCas9	negative selection	4577577
48256177	48256199	13	-	27760321	MV411	viability	CACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.025706699972321653	[495,347]	[174,413]	0	hSpCas9	negative selection	4577578
48256327	48256349	13	-	27760321	MV411	viability	TATCTGCAAACTCTGGGACAGG	ITM2B	ENSG00000136156	-0.500603675339622	[566,506]	[182,350]	-3	hSpCas9	negative selection	4577579
48258135	48258157	13	+	27760321	MV411	viability	GCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	1.2057348104501284	[103,81]	[194,58]	8	hSpCas9	negative selection	4577580
48258198	48258220	13	-	27760321	MV411	viability	ACTCCAGTAGGTTTCTGGGTGG	ITM2B	ENSG00000136156	-1.114956906005619	[584,460]	[61,302]	-6	hSpCas9	negative selection	4577581
48233445	48233467	13	+	27760321	HL60	viability	ATCCCCCCCGACGCCGTCGCGG	ITM2B	ENSG00000136156	-0.3849606103594868	[900,733]	[418,603]	-4	hSpCas9	negative selection	4661040
48256177	48256199	13	-	27760321	HL60	viability	CACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.23284686975566832	[495,347]	[209,374]	-3	hSpCas9	negative selection	4661041
48256327	48256349	13	-	27760321	HL60	viability	TATCTGCAAACTCTGGGACAGG	ITM2B	ENSG00000136156	-0.6135737978629852	[566,506]	[263,309]	-6	hSpCas9	negative selection	4661042
48258135	48258157	13	+	27760321	HL60	viability	GCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.6745127736942791	[103,81]	[102,138]	7	hSpCas9	negative selection	4661043
48258198	48258220	13	-	27760321	HL60	viability	ACTCCAGTAGGTTTCTGGGTGG	ITM2B	ENSG00000136156	-0.3067060643178924	[584,460]	[315,371]	-3	hSpCas9	negative selection	4661044
48233445	48233467	13	+	27760321	HT1080	viability	ATCCCCCCCGACGCCGTCGCGG	ITM2B	ENSG00000136156	-3.2143820137391517	[733,572]	[7,49]	-7	hSpCas9	negative selection	4744503
48256177	48256199	13	-	27760321	HT1080	viability	CACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-1.6560926556877997	[347,271]	[0,80]	-5	hSpCas9	negative selection	4744504
48256327	48256349	13	-	27760321	HT1080	viability	TATCTGCAAACTCTGGGACAGG	ITM2B	ENSG00000136156	2.4745179898833802	[506,395]	[1709,221]	9	hSpCas9	negative selection	4744505
48258135	48258157	13	+	27760321	HT1080	viability	GCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	-1.3993833232578257	[81,63]	[0,21]	-5	hSpCas9	negative selection	4744506
48258198	48258220	13	-	27760321	HT1080	viability	ACTCCAGTAGGTTTCTGGGTGG	ITM2B	ENSG00000136156	-1.3721290276494134	[460,359]	[87,35]	-5	hSpCas9	negative selection	4744507
48233445	48233467	13	+	27760321	HT29	viability after 7 days	ATCCCCCCCGACGCCGTCGCGG	ITM2B	ENSG00000136156	-0.2774090824925246	[733,572]	[767,869,458]	-4	hSpCas9	negative selection	4827966
48256177	48256199	13	-	27760321	HT29	viability after 7 days	CACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.4203366084356684	[347,271]	[420,391,103]	-6	hSpCas9	negative selection	4827967
48256327	48256349	13	-	27760321	HT29	viability after 7 days	TATCTGCAAACTCTGGGACAGG	ITM2B	ENSG00000136156	-0.28360502615074346	[506,395]	[652,382,420]	-4	hSpCas9	negative selection	4827968
48258135	48258157	13	+	27760321	HT29	viability after 7 days	GCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.44695574025430473	[81,63]	[122,133,125]	6	hSpCas9	negative selection	4827969
48258198	48258220	13	-	27760321	HT29	viability after 7 days	ACTCCAGTAGGTTTCTGGGTGG	ITM2B	ENSG00000136156	-0.23107885255410945	[460,359]	[393,608,340]	-3	hSpCas9	negative selection	4827970
48233445	48233467	13	+	27760321	HT29	viability after 25 days	ATCCCCCCCGACGCCGTCGCGG	ITM2B	ENSG00000136156	-3.082948704357844	[733,572]	[86,143,26]	-8	hSpCas9	negative selection	4911429
48256177	48256199	13	-	27760321	HT29	viability after 25 days	CACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.7831496745168232	[347,271]	[258,174,176]	-6	hSpCas9	negative selection	4911430
48256327	48256349	13	-	27760321	HT29	viability after 25 days	TATCTGCAAACTCTGGGACAGG	ITM2B	ENSG00000136156	0.03628482211183315	[506,395]	[377,612,613]	0	hSpCas9	negative selection	4911431
48258135	48258157	13	+	27760321	HT29	viability after 25 days	GCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	1.0200439752535595	[81,63]	[120,179,213]	9	hSpCas9	negative selection	4911432
48258198	48258220	13	-	27760321	HT29	viability after 25 days	ACTCCAGTAGGTTTCTGGGTGG	ITM2B	ENSG00000136156	-0.33813275093325135	[460,359]	[465,319,314]	-3	hSpCas9	negative selection	4911433
48233445	48233467	13	+	27760321	HT29	viability after 22 days	ATCCCCCCCGACGCCGTCGCGG	ITM2B	ENSG00000136156	-2.209067783580994	[733,572]	[52,292,146]	-8	hSpCas9	negative selection	4994892
48256177	48256199	13	-	27760321	HT29	viability after 22 days	CACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.2781207167634433	[347,271]	[267,368,249]	-3	hSpCas9	negative selection	4994893
48256327	48256349	13	-	27760321	HT29	viability after 22 days	TATCTGCAAACTCTGGGACAGG	ITM2B	ENSG00000136156	0.1779792738747386	[506,395]	[509,641,621]	1	hSpCas9	negative selection	4994894
48258135	48258157	13	+	27760321	HT29	viability after 22 days	GCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.5302893132253275	[81,63]	[112,117,134]	6	hSpCas9	negative selection	4994895
48258198	48258220	13	-	27760321	HT29	viability after 22 days	ACTCCAGTAGGTTTCTGGGTGG	ITM2B	ENSG00000136156	-0.07187404028088754	[460,359]	[407,254,694]	0	hSpCas9	negative selection	4994896
48233445	48233467	13	+	27760321	HT29	viability after 19 days	ATCCCCCCCGACGCCGTCGCGG	ITM2B	ENSG00000136156	-2.0445472531235596	[733,572]	[253,61,232]	-8	hSpCas9	negative selection	5078355
48256177	48256199	13	-	27760321	HT29	viability after 19 days	CACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.5035122409065642	[347,271]	[293,243,217]	-4	hSpCas9	negative selection	5078356
48256327	48256349	13	-	27760321	HT29	viability after 19 days	TATCTGCAAACTCTGGGACAGG	ITM2B	ENSG00000136156	-0.08398684962808817	[506,395]	[521,699,251]	-1	hSpCas9	negative selection	5078357
48258135	48258157	13	+	27760321	HT29	viability after 19 days	GCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.3693531117588602	[81,63]	[79,90,147]	3	hSpCas9	negative selection	5078358
48258198	48258220	13	-	27760321	HT29	viability after 19 days	ACTCCAGTAGGTTTCTGGGTGG	ITM2B	ENSG00000136156	-0.3030950012003322	[460,359]	[570,389,206]	-3	hSpCas9	negative selection	5078359
48233445	48233467	13	+	27760321	HT29	viability after 16 days	ATCCCCCCCGACGCCGTCGCGG	ITM2B	ENSG00000136156	-2.377282390074874	[733,572]	[177,89,158]	-8	hSpCas9	negative selection	5161818
48256177	48256199	13	-	27760321	HT29	viability after 16 days	CACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.1895572566317561	[347,271]	[326,325,260]	-2	hSpCas9	negative selection	5161819
48256327	48256349	13	-	27760321	HT29	viability after 16 days	TATCTGCAAACTCTGGGACAGG	ITM2B	ENSG00000136156	0.19648788352483476	[506,395]	[621,524,594]	2	hSpCas9	negative selection	5161820
48258135	48258157	13	+	27760321	HT29	viability after 16 days	GCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.4822678788233923	[81,63]	[172,68,106]	5	hSpCas9	negative selection	5161821
48258198	48258220	13	-	27760321	HT29	viability after 16 days	ACTCCAGTAGGTTTCTGGGTGG	ITM2B	ENSG00000136156	-0.20746175449379212	[460,359]	[392,542,252]	-2	hSpCas9	negative selection	5161822
48233445	48233467	13	+	27760321	HT29	viability after 13 days	ATCCCCCCCGACGCCGTCGCGG	ITM2B	ENSG00000136156	-1.624104918285958	[733,572]	[266,211,257]	-8	hSpCas9	negative selection	5245281
48256177	48256199	13	-	27760321	HT29	viability after 13 days	CACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	0.06572511305657527	[347,271]	[474,362,295]	0	hSpCas9	negative selection	5245282
48256327	48256349	13	-	27760321	HT29	viability after 13 days	TATCTGCAAACTCTGGGACAGG	ITM2B	ENSG00000136156	0.10035953918806789	[506,395]	[609,658,423]	1	hSpCas9	negative selection	5245283
48258135	48258157	13	+	27760321	HT29	viability after 13 days	GCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.22213437387828217	[81,63]	[26,110,154]	2	hSpCas9	negative selection	5245284
48258198	48258220	13	-	27760321	HT29	viability after 13 days	ACTCCAGTAGGTTTCTGGGTGG	ITM2B	ENSG00000136156	-0.0622087130711553	[460,359]	[474,363,524]	0	hSpCas9	negative selection	5245285
48233445	48233467	13	+	27760321	HT29	viability after 10 days	ATCCCCCCCGACGCCGTCGCGG	ITM2B	ENSG00000136156	-1.0909432386907916	[733,572]	[497,329,320]	-8	hSpCas9	negative selection	5328744
48256177	48256199	13	-	27760321	HT29	viability after 10 days	CACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	0.31125935915306824	[347,271]	[371,672,402]	4	hSpCas9	negative selection	5328745
48256327	48256349	13	-	27760321	HT29	viability after 10 days	TATCTGCAAACTCTGGGACAGG	ITM2B	ENSG00000136156	0.06465904069037359	[506,395]	[629,557,579]	0	hSpCas9	negative selection	5328746
48258135	48258157	13	+	27760321	HT29	viability after 10 days	GCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	-0.5677502452026317	[81,63]	[43,79,60]	-6	hSpCas9	negative selection	5328747
48258198	48258220	13	-	27760321	HT29	viability after 10 days	ACTCCAGTAGGTTTCTGGGTGG	ITM2B	ENSG00000136156	-0.2549915605413436	[460,359]	[478,397,410]	-3	hSpCas9	negative selection	5328748
48233445	48233467	13	+	27760321	MOLM13	viability	ATCCCCCCCGACGCCGTCGCGG	ITM2B	ENSG00000136156	-0.9710654231484223	[900,733]	[279,194]	-5	hSpCas9	negative selection	5412207
48256177	48256199	13	-	27760321	MOLM13	viability	CACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.44160594721070007	[495,347]	[302,62]	-3	hSpCas9	negative selection	5412208
48256327	48256349	13	-	27760321	MOLM13	viability	TATCTGCAAACTCTGGGACAGG	ITM2B	ENSG00000136156	-0.653743686751969	[566,506]	[234,155]	-4	hSpCas9	negative selection	5412209
48258135	48258157	13	+	27760321	MOLM13	viability	GCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	1.008492835634076	[103,81]	[166,51]	7	hSpCas9	negative selection	5412210
48258198	48258220	13	-	27760321	MOLM13	viability	ACTCCAGTAGGTTTCTGGGTGG	ITM2B	ENSG00000136156	-1.6532677568000733	[584,460]	[76,106]	-7	hSpCas9	negative selection	5412211
48233369	48233392	13	+	27661255	K562	viability	GGTGACGTTCAACTCCGCTCTGG	ITM2B	ENSG00000136156	0.13794126608842605	[144,131]	[88,149]	5	dCas9-KRAB	negative selection	5487473
48233525	48233548	13	+	27661255	K562	viability	GAGGGCTGCGCGGACTGCAGCGG	ITM2B	ENSG00000136156	0.10931811795995017	[1443,1580]	[1386,1227]	4	dCas9-KRAB	negative selection	5487474
48233650	48233673	13	+	27661255	K562	viability	GGAAGTGCGTGTGCTGGAAGCGG	ITM2B	ENSG00000136156	0.14939240182500957	[1057,1149]	[1089,879]	5	dCas9-KRAB	negative selection	5487475
48256177	48256200	13	-	27260156	BXPC3	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.08770115191716854	[882]	[808,829,828,1028]	-2	hSpCas9	negative selection	5549971
48253868	48253891	13	+	27260156	BXPC3	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.2414276013367077	[372]	[437,385,438,601]	5	hSpCas9	negative selection	5549972
48256177	48256200	13	+	27260156	BXPC3	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.08602665817361832	[831]	[875,862,842,1138]	1	hSpCas9	negative selection	5549973
48258134	48258157	13	+	27260156	BXPC3	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.06349369363024632	[594]	[450,694,673,815]	1	hSpCas9	negative selection	5614226
48258194	48258217	13	+	27260156	BXPC3	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.192858165168717	[708]	[906,871,799,787]	4	hSpCas9	negative selection	5614227
48253811	48253834	13	-	27260156	BXPC3	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.034164151595893255	[1200]	[1116,1241,1294,1531]	0	hSpCas9	negative selection	5614228
48256177	48256200	13	-	27260156	A673	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.05365296216787163	[882]	[1103,779,1110,1108]	-1	hSpCas9	negative selection	5671222
48253868	48253891	13	+	27260156	A673	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.05150514920004062	[372]	[474,459,502,415]	1	hSpCas9	negative selection	5671223
48256177	48256200	13	+	27260156	A673	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.08841069660149359	[831]	[1051,893,1123,1185]	2	hSpCas9	negative selection	5671224
48258134	48258157	13	+	27260156	A673	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.3100865057859394	[594]	[894,753,959,938]	7	hSpCas9	negative selection	5735477
48258194	48258217	13	+	27260156	A673	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.4209461317443458	[708]	[1307,1058,996,1219]	8	hSpCas9	negative selection	5735478
48253811	48253834	13	-	27260156	A673	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.07319543054513855	[1200]	[1660,1438,1431,1554]	1	hSpCas9	negative selection	5735479
48256177	48256200	13	-	27260156	A375	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.0453401427578507	[882]	[1006,1013,1031,948]	0	hSpCas9	negative selection	5792473
48253868	48253891	13	+	27260156	A375	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.3568586198299939	[372]	[469,726,530,527]	5	hSpCas9	negative selection	5792474
48256177	48256200	13	+	27260156	A375	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.06580534223701429	[831]	[1269,1097,668,723]	-1	hSpCas9	negative selection	5792475
48258134	48258157	13	+	27260156	A375	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.28385785296499294	[594]	[775,853,964,792]	4	hSpCas9	negative selection	5856728
48258194	48258217	13	+	27260156	A375	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.6828348993159609	[708]	[1219,1635,1463,1065]	8	hSpCas9	negative selection	5856729
48253811	48253834	13	-	27260156	A375	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.09802045730401465	[1200]	[1630,1871,1480,1114]	1	hSpCas9	negative selection	5856730
48256177	48256200	13	-	27260156	COLO741	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.020006706348505432	[882]	[1192,1047,1101]	0	hSpCas9	negative selection	5913724
48253868	48253891	13	+	27260156	COLO741	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.12891783519879416	[372]	[637,469,467]	2	hSpCas9	negative selection	5913725
48256177	48256200	13	+	27260156	COLO741	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.1845949757081321	[831]	[990,984,839]	-4	hSpCas9	negative selection	5913726
48258134	48258157	13	+	27260156	COLO741	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.13582086947588118	[594]	[915,610,972]	3	hSpCas9	negative selection	5977979
48258194	48258217	13	+	27260156	COLO741	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.38379762327090816	[708]	[1158,1166,1212]	7	hSpCas9	negative selection	5977980
48253811	48253834	13	-	27260156	COLO741	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.12990967885170757	[1200]	[1612,2026,1408]	2	hSpCas9	negative selection	5977981
48256177	48256200	13	-	27260156	CAL120	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.3447649598858781	[882]	[841,781,965]	-5	hSpCas9	negative selection	6034975
48253868	48253891	13	+	27260156	CAL120	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	-0.16039699910792238	[372]	[441,403,403]	-2	hSpCas9	negative selection	6034976
48256177	48256200	13	+	27260156	CAL120	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.1767049125094522	[831]	[1636,1083,864]	2	hSpCas9	negative selection	6034977
48258134	48258157	13	+	27260156	CAL120	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	-0.050734690635853064	[594]	[883,814,474]	0	hSpCas9	negative selection	6099230
48258194	48258217	13	+	27260156	CAL120	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.5151272530468539	[708]	[1146,1135,1477]	7	hSpCas9	negative selection	6099231
48253811	48253834	13	-	27260156	CAL120	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.16361888705160132	[1200]	[1949,1449,1662]	2	hSpCas9	negative selection	6099232
48256177	48256200	13	-	27260156	CADOES1	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.10872552555768111	[882]	[701,773,825,743]	-2	hSpCas9	negative selection	6156226
48253868	48253891	13	+	27260156	CADOES1	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.11960507073428783	[372]	[352,356,435,360]	2	hSpCas9	negative selection	6156227
48256177	48256200	13	+	27260156	CADOES1	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.15410390756097148	[831]	[784,718,798,1151]	2	hSpCas9	negative selection	6156228
48258134	48258157	13	+	27260156	CADOES1	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.20086848746586355	[594]	[742,608,578,611]	3	hSpCas9	negative selection	6220481
48258194	48258217	13	+	27260156	CADOES1	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.22270324931867858	[708]	[955,692,793,628]	4	hSpCas9	negative selection	6220482
48253811	48253834	13	-	27260156	CADOES1	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	-0.030315982847347822	[1200]	[1030,1091,1036,1219]	0	hSpCas9	negative selection	6220483
48256177	48256200	13	-	27260156	EWS502	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.14724000326815	[882]	[729,764,875,1034]	-3	hSpCas9	negative selection	6277477
48253868	48253891	13	+	27260156	EWS502	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.1863244076825647	[372]	[458,460,399,475]	3	hSpCas9	negative selection	6277478
48256177	48256200	13	+	27260156	EWS502	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.02111140581383031	[831]	[997,816,844,903]	0	hSpCas9	negative selection	6277479
48258134	48258157	13	+	27260156	EWS502	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.0789196648090299	[594]	[682,511,806,663]	1	hSpCas9	negative selection	6341732
48258194	48258217	13	+	27260156	EWS502	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.23098023053577743	[708]	[915,821,811,975]	4	hSpCas9	negative selection	6341733
48253811	48253834	13	-	27260156	EWS502	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.11670371867715867	[1200]	[1195,1744,1459,1098]	2	hSpCas9	negative selection	6341734
48256177	48256200	13	-	27260156	EW8	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.2398775714506557	[882]	[729,500,721,462]	-4	hSpCas9	negative selection	6398728
48253868	48253891	13	+	27260156	EW8	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.5628879570308829	[372]	[538,481,347,442]	8	hSpCas9	negative selection	6398729
48256177	48256200	13	+	27260156	EW8	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.008924704265422911	[831]	[735,843,555,603]	0	hSpCas9	negative selection	6398730
48258134	48258157	13	+	27260156	EW8	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.22610285959376536	[594]	[619,599,569,469]	4	hSpCas9	negative selection	6462983
48258194	48258217	13	+	27260156	EW8	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.32069065477818315	[708]	[629,923,819,468]	6	hSpCas9	negative selection	6462984
48253811	48253834	13	-	27260156	EW8	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	-0.005119328928958833	[1200]	[1280,855,722,1091]	0	hSpCas9	negative selection	6462985
48256177	48256200	13	-	27260156	CORL105	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.026861901344904737	[882]	[1088,1032,1090,859]	0	hSpCas9	negative selection	6519979
48253868	48253891	13	+	27260156	CORL105	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.48517039626220726	[372]	[517,595,677,659]	8	hSpCas9	negative selection	6519980
48256177	48256200	13	+	27260156	CORL105	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.09077452216409376	[831]	[1184,909,1128,946]	1	hSpCas9	negative selection	6519981
48258134	48258157	13	+	27260156	CORL105	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.20940250358565043	[594]	[782,748,997,721]	4	hSpCas9	negative selection	6584234
48258194	48258217	13	+	27260156	CORL105	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.19994269012137866	[708]	[938,781,994,1105]	4	hSpCas9	negative selection	6584235
48253811	48253834	13	-	27260156	CORL105	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	-0.013498097356602567	[1200]	[1494,1471,1387,1217]	0	hSpCas9	negative selection	6584236
48256177	48256200	13	-	27260156	HS294T	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	0.31157090612745864	[882]	[306,554,425,409]	4	hSpCas9	negative selection	6641230
48253868	48253891	13	+	27260156	HS294T	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.024316643700083962	[372]	[190,100,156,131]	0	hSpCas9	negative selection	6641231
48256177	48256200	13	+	27260156	HS294T	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.13614417081292451	[831]	[278,368,225,294]	-2	hSpCas9	negative selection	6641232
48258134	48258157	13	+	27260156	HS294T	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	-0.05223773235337087	[594]	[153,247,245,248]	0	hSpCas9	negative selection	6705485
48258194	48258217	13	+	27260156	HS294T	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.5205818948885638	[708]	[692,240,233,376]	7	hSpCas9	negative selection	6705486
48253811	48253834	13	-	27260156	HS294T	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.20665789786276	[1200]	[523,518,476,640]	3	hSpCas9	negative selection	6705487
48256177	48256200	13	-	27260156	HCC44	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	0.09797539367326291	[882]	[799,942,1476,1108]	1	hSpCas9	negative selection	6762481
48253868	48253891	13	+	27260156	HCC44	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.4225547238110407	[372]	[709,693,469,367]	7	hSpCas9	negative selection	6762482
48256177	48256200	13	+	27260156	HCC44	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.19114765322337268	[831]	[1118,1119,1218,859]	3	hSpCas9	negative selection	6762483
48258134	48258157	13	+	27260156	HCC44	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.4485714326671711	[594]	[595,935,1498,709]	7	hSpCas9	negative selection	6826736
48258194	48258217	13	+	27260156	HCC44	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.3109340746235404	[708]	[1236,1000,1041,728]	5	hSpCas9	negative selection	6826737
48253811	48253834	13	-	27260156	HCC44	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.28195884735448873	[1200]	[1718,1481,1621,1789]	4	hSpCas9	negative selection	6826738
48256177	48256200	13	-	27260156	G402	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	0.0028855589960110617	[882]	[695,1162,1353,1051]	0	hSpCas9	negative selection	6883732
48253868	48253891	13	+	27260156	G402	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.32664996155597154	[372]	[883,503,484,454]	4	hSpCas9	negative selection	6883733
48256177	48256200	13	+	27260156	G402	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.29972793909330353	[831]	[996,830,793,704]	-4	hSpCas9	negative selection	6883734
48258134	48258157	13	+	27260156	G402	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.4017833979278724	[594]	[751,1054,986,1011]	5	hSpCas9	negative selection	6947987
48258194	48258217	13	+	27260156	G402	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.031962239404774384	[708]	[764,815,955,971]	0	hSpCas9	negative selection	6947988
48253811	48253834	13	-	27260156	G402	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	-0.010760615123819095	[1200]	[1513,1831,1102,1396]	0	hSpCas9	negative selection	6947989
48256177	48256200	13	-	27260156	L33	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.07810240406973856	[882]	[968,357,438,800]	-2	hSpCas9	negative selection	7004983
48253868	48253891	13	+	27260156	L33	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	-0.29257949376779274	[372]	[291,130,202,283]	-6	hSpCas9	negative selection	7004984
48256177	48256200	13	+	27260156	L33	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.38772780605643814	[831]	[642,258,406,620]	-7	hSpCas9	negative selection	7004985
48258134	48258157	13	+	27260156	L33	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.08859680225842509	[594]	[622,278,399,590]	2	hSpCas9	negative selection	7069238
48258194	48258217	13	+	27260156	L33	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	-0.3853128968392182	[708]	[528,247,314,535]	-7	hSpCas9	negative selection	7069239
48253811	48253834	13	-	27260156	L33	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	-0.0656665047518612	[1200]	[1066,432,765,1248]	-1	hSpCas9	negative selection	7069240
48256177	48256200	13	-	27260156	K562	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	0.07979912375937626	[882]	[1140,793,711,700]	1	hSpCas9	negative selection	7126234
48253868	48253891	13	+	27260156	K562	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.11106612395572552	[372]	[463,421,351,218]	1	hSpCas9	negative selection	7126235
48256177	48256200	13	+	27260156	K562	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.026069444263814634	[831]	[592,1221,290,797]	0	hSpCas9	negative selection	7126236
48258134	48258157	13	+	27260156	K562	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.2672423833090332	[594]	[424,707,702,683]	3	hSpCas9	negative selection	7190489
48258194	48258217	13	+	27260156	K562	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.20683009684422704	[708]	[890,698,977,385]	2	hSpCas9	negative selection	7190490
48253811	48253834	13	-	27260156	K562	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.24139731614077165	[1200]	[1206,1194,1415,1213]	3	hSpCas9	negative selection	7190491
48256177	48256200	13	-	27260156	HT29	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.03512023608827486	[882]	[1219,1146,866,978]	0	hSpCas9	negative selection	7247485
48253868	48253891	13	+	27260156	HT29	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.42034492562496395	[372]	[488,640,745,547]	7	hSpCas9	negative selection	7247486
48256177	48256200	13	+	27260156	HT29	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.05856188067048129	[831]	[1150,1075,1069,932]	1	hSpCas9	negative selection	7247487
48258134	48258157	13	+	27260156	HT29	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.21709233220040353	[594]	[845,918,964,656]	4	hSpCas9	negative selection	7311740
48258194	48258217	13	+	27260156	HT29	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.40217718933360247	[708]	[1360,1257,1051,929]	7	hSpCas9	negative selection	7311741
48253811	48253834	13	-	27260156	HT29	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.10445468025510896	[1200]	[1384,1793,1595,1504]	2	hSpCas9	negative selection	7311742
48256177	48256200	13	-	27260156	MHHES1	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	0.10996683976079369	[882]	[788,1396,1183,930]	2	hSpCas9	negative selection	7368736
48253868	48253891	13	+	27260156	MHHES1	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.12961205541362947	[372]	[631,391,458,377]	2	hSpCas9	negative selection	7368737
48256177	48256200	13	+	27260156	MHHES1	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.21889770121013918	[831]	[1334,1122,1163,813]	4	hSpCas9	negative selection	7368738
48258134	48258157	13	+	27260156	MHHES1	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.4009976903263383	[594]	[942,809,899,868]	7	hSpCas9	negative selection	7432991
48258194	48258217	13	+	27260156	MHHES1	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.43451134823159177	[708]	[1428,1202,1095,706]	7	hSpCas9	negative selection	7432992
48253811	48253834	13	-	27260156	MHHES1	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.1559842888471743	[1200]	[2184,1579,1524,929]	3	hSpCas9	negative selection	7432993
48256177	48256200	13	-	27260156	MEWO	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.05379695207399182	[882]	[947,772,695]	-1	hSpCas9	negative selection	7489987
48253868	48253891	13	+	27260156	MEWO	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	-0.028237034623410096	[372]	[338,322,363]	0	hSpCas9	negative selection	7489988
48256177	48256200	13	+	27260156	MEWO	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.23303417712540786	[831]	[1253,715,840]	5	hSpCas9	negative selection	7489989
48258134	48258157	13	+	27260156	MEWO	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.18154032915080726	[594]	[656,579,661]	4	hSpCas9	negative selection	7554242
48258194	48258217	13	+	27260156	MEWO	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.39516753639575253	[708]	[1117,741,804]	8	hSpCas9	negative selection	7554243
48253811	48253834	13	-	27260156	MEWO	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.07928111114606229	[1200]	[1402,1149,1049]	1	hSpCas9	negative selection	7554244
48256177	48256200	13	-	27260156	LNCAPCLONEFGC	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.10277157446887364	[882]	[745,734,733,762]	-2	hSpCas9	negative selection	7611238
48253868	48253891	13	+	27260156	LNCAPCLONEFGC	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.44125312718998766	[372]	[442,317,509,580]	7	hSpCas9	negative selection	7611239
48256177	48256200	13	+	27260156	LNCAPCLONEFGC	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.05099907577017093	[831]	[825,738,837,729]	0	hSpCas9	negative selection	7611240
48258134	48258157	13	+	27260156	LNCAPCLONEFGC	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.340017027787096	[594]	[890,605,712,523]	5	hSpCas9	negative selection	7675493
48258194	48258217	13	+	27260156	LNCAPCLONEFGC	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.5228272202306031	[708]	[954,966,808,938]	7	hSpCas9	negative selection	7675494
48253811	48253834	13	-	27260156	LNCAPCLONEFGC	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.12816269769507693	[1200]	[965,1036,1521,1293]	2	hSpCas9	negative selection	7675495
48256177	48256200	13	-	27260156	PANC0327	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	0.16201079612477376	[882]	[947,978,911,663]	2	hSpCas9	negative selection	7732489
48253868	48253891	13	+	27260156	PANC0327	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.40265383446924496	[372]	[464,376,452,466]	6	hSpCas9	negative selection	7732490
48256177	48256200	13	+	27260156	PANC0327	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.06788887719544157	[831]	[746,595,430,1062]	-1	hSpCas9	negative selection	7732491
48258134	48258157	13	+	27260156	PANC0327	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.2902560366088876	[594]	[628,721,648,573]	4	hSpCas9	negative selection	7796744
48258194	48258217	13	+	27260156	PANC0327	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.27969696341792993	[708]	[702,797,933,613]	4	hSpCas9	negative selection	7796745
48253811	48253834	13	-	27260156	PANC0327	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.2566250429046284	[1200]	[1780,913,1297,1192]	4	hSpCas9	negative selection	7796746
48256177	48256200	13	-	27260156	NCIH2009	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	0.26668755138437483	[882]	[1990,1384,1175]	3	hSpCas9	negative selection	7853740
48253868	48253891	13	+	27260156	NCIH2009	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.12237334481443124	[372]	[647,611,455]	1	hSpCas9	negative selection	7853741
48256177	48256200	13	+	27260156	NCIH2009	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.30277240023188645	[831]	[1108,912,836]	-4	hSpCas9	negative selection	7853742
48258134	48258157	13	+	27260156	NCIH2009	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.1694472540808603	[594]	[1057,795,975]	2	hSpCas9	negative selection	7917995
48258194	48258217	13	+	27260156	NCIH2009	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	-0.1526781310695336	[708]	[1228,813,696]	-2	hSpCas9	negative selection	7917996
48253811	48253834	13	-	27260156	NCIH2009	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	-0.0257570306337922	[1200]	[1493,1404,2016]	0	hSpCas9	negative selection	7917997
48256177	48256200	13	-	27260156	NCIH1373	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	0.3354060771250643	[882]	[1428,1004,1186,376]	3	hSpCas9	negative selection	7974991
48253868	48253891	13	+	27260156	NCIH1373	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.37259636985080713	[372]	[593,940,337,62]	3	hSpCas9	negative selection	7974992
48256177	48256200	13	+	27260156	NCIH1373	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.1130947530103047	[831]	[1824,659,731,257]	1	hSpCas9	negative selection	7974993
48258134	48258157	13	+	27260156	NCIH1373	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.050663535977451435	[594]	[679,539,738,215]	0	hSpCas9	negative selection	8039246
48258194	48258217	13	+	27260156	NCIH1373	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	-0.7063681150880783	[708]	[548,419,449,143]	-6	hSpCas9	negative selection	8039247
48253811	48253834	13	-	27260156	NCIH1373	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.10286640659237434	[1200]	[2346,1160,1001,379]	1	hSpCas9	negative selection	8039248
48256177	48256200	13	-	27260156	PATU8902	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.030566674822097184	[882]	[1267,1179,798,1725]	0	hSpCas9	negative selection	8096242
48253868	48253891	13	+	27260156	PATU8902	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.8620069332033662	[372]	[837,735,685,1662]	8	hSpCas9	negative selection	8096243
48256177	48256200	13	+	27260156	PATU8902	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.022907022156067547	[831]	[1363,1021,658,1695]	0	hSpCas9	negative selection	8096244
48258134	48258157	13	+	27260156	PATU8902	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.3487074800878563	[594]	[532,934,1249,1503]	3	hSpCas9	negative selection	8160497
48258194	48258217	13	+	27260156	PATU8902	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.7606801444823345	[708]	[1862,1559,1725,1490]	7	hSpCas9	negative selection	8160498
48253811	48253834	13	-	27260156	PATU8902	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.29119656037735386	[1200]	[1844,2145,1743,2580]	3	hSpCas9	negative selection	8160499
48256177	48256200	13	-	27260156	PANC1	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.2689102602535276	[882]	[507,986,497,594]	-4	hSpCas9	negative selection	8217493
48253868	48253891	13	+	27260156	PANC1	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.17525324091637515	[372]	[393,441,331,298]	2	hSpCas9	negative selection	8217494
48256177	48256200	13	+	27260156	PANC1	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.4786778041806228	[831]	[782,1928,917,598]	7	hSpCas9	negative selection	8217495
48258134	48258157	13	+	27260156	PANC1	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.5455953024336135	[594]	[603,988,864,592]	8	hSpCas9	negative selection	8281748
48258194	48258217	13	+	27260156	PANC1	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.2506267546807258	[708]	[703,767,797,639]	4	hSpCas9	negative selection	8281749
48253811	48253834	13	-	27260156	PANC1	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	-0.016048302913207246	[1200]	[1162,1216,922,828]	0	hSpCas9	negative selection	8281750
48256177	48256200	13	-	27260156	PANC0813	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	0.12578796439872175	[882]	[1180,1145,1118,1085]	2	hSpCas9	negative selection	8338744
48253868	48253891	13	+	27260156	PANC0813	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.22034294931520154	[372]	[734,645,306,379]	3	hSpCas9	negative selection	8338745
48256177	48256200	13	+	27260156	PANC0813	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.2812434795656672	[831]	[900,1069,626,634]	-4	hSpCas9	negative selection	8338746
48258134	48258157	13	+	27260156	PANC0813	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.24509197720739012	[594]	[819,917,577,984]	4	hSpCas9	negative selection	8402999
48258194	48258217	13	+	27260156	PANC0813	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	-0.1220978780907962	[708]	[782,674,825,776]	-2	hSpCas9	negative selection	8403000
48253811	48253834	13	-	27260156	PANC0813	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	-0.11629629978425426	[1200]	[1339,1288,1392,1191]	-2	hSpCas9	negative selection	8403001
48256177	48256200	13	-	27260156	RDES	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.19330528384322487	[882]	[804,779,690,1337]	-3	hSpCas9	negative selection	8459995
48253868	48253891	13	+	27260156	RDES	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.42558159576689597	[372]	[513,488,699,615]	6	hSpCas9	negative selection	8459996
48256177	48256200	13	+	27260156	RDES	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.07050065498523705	[831]	[777,885,898,1114]	-1	hSpCas9	negative selection	8459997
48258134	48258157	13	+	27260156	RDES	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.12328492787254436	[594]	[692,617,746,954]	2	hSpCas9	negative selection	8524250
48258194	48258217	13	+	27260156	RDES	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.2941034378000914	[708]	[900,888,976,1272]	5	hSpCas9	negative selection	8524251
48253811	48253834	13	-	27260156	RDES	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.06474765005290672	[1200]	[1206,1434,1571,1599]	1	hSpCas9	negative selection	8524252
48256177	48256200	13	-	27260156	PC3	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.27449071613969744	[882]	[497,603,1205,824]	-6	hSpCas9	negative selection	8581246
48253868	48253891	13	+	27260156	PC3	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.17701074186336455	[372]	[248,351,694,537]	4	hSpCas9	negative selection	8581247
48256177	48256200	13	+	27260156	PC3	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.19093404586222773	[831]	[426,677,1153,887]	-4	hSpCas9	negative selection	8581248
48258134	48258157	13	+	27260156	PC3	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	-0.02035028917953441	[594]	[289,507,1235,649]	0	hSpCas9	negative selection	8645501
48258194	48258217	13	+	27260156	PC3	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.12952595576955317	[708]	[412,998,1073,801]	3	hSpCas9	negative selection	8645502
48253811	48253834	13	-	27260156	PC3	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.07462473863389518	[1200]	[814,1246,2011,1333]	1	hSpCas9	negative selection	8645503
48256177	48256200	13	-	27260156	PATU8988T	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.09797260238232475	[882]	[936,810,657,784]	-2	hSpCas9	negative selection	8702497
48253868	48253891	13	+	27260156	PATU8988T	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.732809815926679	[372]	[707,421,537,721]	9	hSpCas9	negative selection	8702498
48256177	48256200	13	+	27260156	PATU8988T	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.1532185903241723	[831]	[616,682,735,862]	-3	hSpCas9	negative selection	8702499
48258134	48258157	13	+	27260156	PATU8988T	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.46632220780507233	[594]	[630,925,787,848]	7	hSpCas9	negative selection	8766752
48258194	48258217	13	+	27260156	PATU8988T	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.20669246740474867	[708]	[1004,927,611,618]	3	hSpCas9	negative selection	8766753
48253811	48253834	13	-	27260156	PATU8988T	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	-0.18715180736366555	[1200]	[799,1184,888,1237]	-3	hSpCas9	negative selection	8766754
48256177	48256200	13	-	27260156	T47D	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.0279415289381012	[882]	[1040,829,1019,1164]	0	hSpCas9	negative selection	8823748
48253868	48253891	13	+	27260156	T47D	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.140612309241025	[372]	[475,450,528,460]	3	hSpCas9	negative selection	8823749
48256177	48256200	13	+	27260156	T47D	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.04200507967551592	[831]	[1088,870,982,1061]	0	hSpCas9	negative selection	8823750
48258134	48258157	13	+	27260156	T47D	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.266159627127404	[594]	[820,837,811,863]	5	hSpCas9	negative selection	8888003
48258194	48258217	13	+	27260156	T47D	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.104181493198234	[708]	[944,923,824,853]	2	hSpCas9	negative selection	8888004
48253811	48253834	13	-	27260156	T47D	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.07598011521999926	[1200]	[1660,1265,1455,1536]	1	hSpCas9	negative selection	8888005
48256177	48256200	13	-	27260156	SU8686	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	0.1470257921873176	[882]	[980,758,934,1268]	2	hSpCas9	negative selection	8944999
48253868	48253891	13	+	27260156	SU8686	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	-0.10495463573435854	[372]	[282,337,458,295]	-2	hSpCas9	negative selection	8945000
48256177	48256200	13	+	27260156	SU8686	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.027316386263165016	[831]	[675,797,892,897]	0	hSpCas9	negative selection	8945001
48258134	48258157	13	+	27260156	SU8686	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.29425581131397976	[594]	[688,616,757,865]	5	hSpCas9	negative selection	9009254
48258194	48258217	13	+	27260156	SU8686	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	-0.29190758427627256	[708]	[540,446,629,719]	-5	hSpCas9	negative selection	9009255
48253811	48253834	13	-	27260156	SU8686	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.02531745917050099	[1200]	[1030,970,1381,1568]	0	hSpCas9	negative selection	9009256
48256177	48256200	13	-	27260156	SKES1	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.09967858584424161	[882]	[1019,883,826,608]	-2	hSpCas9	negative selection	9066250
48253868	48253891	13	+	27260156	SKES1	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.0722273505591311	[372]	[303,498,390,369]	1	hSpCas9	negative selection	9066251
48256177	48256200	13	+	27260156	SKES1	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.1859536199731493	[831]	[1223,789,858,917]	4	hSpCas9	negative selection	9066252
48258134	48258157	13	+	27260156	SKES1	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.2240091175345224	[594]	[823,776,529,667]	5	hSpCas9	negative selection	9130505
48258194	48258217	13	+	27260156	SKES1	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.2195868253062221	[708]	[954,986,802,604]	5	hSpCas9	negative selection	9130506
48253811	48253834	13	-	27260156	SKES1	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.0189208381429391	[1200]	[1548,1245,1166,961]	0	hSpCas9	negative selection	9130507
48256177	48256200	13	-	27260156	TOV112D	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	0.10941026389501018	[882]	[1011,1027,1108,695]	2	hSpCas9	negative selection	9187501
48253868	48253891	13	+	27260156	TOV112D	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.040436530620791	[372]	[375,486,285,410]	0	hSpCas9	negative selection	9187502
48256177	48256200	13	+	27260156	TOV112D	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.27321370689964986	[831]	[880,1559,996,721]	5	hSpCas9	negative selection	9187503
48258134	48258157	13	+	27260156	TOV112D	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.6001166082667049	[594]	[1021,774,809,980]	9	hSpCas9	negative selection	9251756
48258194	48258217	13	+	27260156	TOV112D	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.34215356203821634	[708]	[756,1367,741,836]	6	hSpCas9	negative selection	9251757
48253811	48253834	13	-	27260156	TOV112D	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.031339672666896634	[1200]	[1319,1216,1200,1182]	0	hSpCas9	negative selection	9251758
48256177	48256200	13	-	27260156	TC71	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.2736268108780988	[882]	[778,824,658,878]	-6	hSpCas9	negative selection	9308752
48253868	48253891	13	+	27260156	TC71	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.1655507076762425	[372]	[477,442,482,383]	4	hSpCas9	negative selection	9308753
48256177	48256200	13	+	27260156	TC71	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.14037527246472647	[831]	[746,915,720,859]	-4	hSpCas9	negative selection	9308754
48258134	48258157	13	+	27260156	TC71	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.0548956656076417	[594]	[826,544,593,683]	1	hSpCas9	negative selection	9373007
48258194	48258217	13	+	27260156	TC71	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.11530939928584827	[708]	[747,870,847,826]	3	hSpCas9	negative selection	9373008
48253811	48253834	13	-	27260156	TC71	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	-0.10934987969078369	[1200]	[1079,1195,1049,1471]	-3	hSpCas9	negative selection	9373009
48256177	48256200	13	-	27260156	TC32	viability	CCACAGTAGTACACGTCATCTGG	ITM2B	ENSG00000136156	-0.1001798981427886	[882]	[712,591,989,874]	-2	hSpCas9	negative selection	9430003
48253868	48253891	13	+	27260156	TC32	viability	GGACTAGCATTTATGCTTGCAGG	ITM2B	ENSG00000136156	0.6404827844976368	[372]	[428,498,678,603]	9	hSpCas9	negative selection	9430004
48256177	48256200	13	+	27260156	TC32	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.18221179968776624	[831]	[674,488,897,771]	-3	hSpCas9	negative selection	9430005
48258134	48258157	13	+	27260156	TC32	viability	AGCCTATTTAGATCTTAACCTGG	ITM2B	ENSG00000136156	0.45694797217554967	[594]	[806,631,1045,622]	7	hSpCas9	negative selection	9494258
48258194	48258217	13	+	27260156	TC32	viability	TATGCCACCCAGAAACCTACTGG	ITM2B	ENSG00000136156	0.2285232867294964	[708]	[697,639,925,906]	4	hSpCas9	negative selection	9494259
48253811	48253834	13	-	27260156	TC32	viability	CCAACTGGTACCACATCATCTGG	ITM2B	ENSG00000136156	0.16747387712183914	[1200]	[1041,1284,1470,1245]	3	hSpCas9	negative selection	9494260
48233378	48233401	13	+	27869803	HPAFII	viability after 27 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	1.6692821377030507	[93]	[310,28,NaN]	9	hSpCas9	negative selection	9550001
48233406	48233429	13	+	27869803	HPAFII	viability after 27 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.4567960309228595	[302]	[168,259,NaN]	3	hSpCas9	negative selection	9550002
48233458	48233481	13	-	27869803	HPAFII	viability after 27 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.6710888944086818	[239]	[219,184,NaN]	5	hSpCas9	negative selection	9550003
48256252	48256275	13	-	27869803	HPAFII	viability after 27 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	0.25892087360040605	[124]	[70,84,NaN]	2	hSpCas9	negative selection	9550004
48233378	48233401	13	+	27869803	HPAFII	viability after 15 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	1.4734301252177973	[93]	[557,107,NaN]	9	hSpCas9	negative selection	9632450
48233406	48233429	13	+	27869803	HPAFII	viability after 15 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.013539863439040456	[302]	[472,238,NaN]	0	hSpCas9	negative selection	9632451
48233458	48233481	13	-	27869803	HPAFII	viability after 15 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.266447011339751	[239]	[264,182,NaN]	-3	hSpCas9	negative selection	9632452
48256252	48256275	13	-	27869803	HPAFII	viability after 15 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	-0.4720810565367013	[124]	[94,97,NaN]	-5	hSpCas9	negative selection	9632453
48233378	48233401	13	+	27869803	ASPC1	viability after 36 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	0.4620437361507427	[352]	[374,15,145]	4	hSpCas9	negative selection	9714899
48233406	48233429	13	+	27869803	ASPC1	viability after 36 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	1.457735354030468	[780]	[379,226,1413]	9	hSpCas9	negative selection	9714900
48233458	48233481	13	-	27869803	ASPC1	viability after 36 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.8457383806234102	[800]	[156,1117,250]	7	hSpCas9	negative selection	9714901
48256252	48256275	13	-	27869803	ASPC1	viability after 36 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	-0.5068864410391913	[238]	[49,29,86]	-5	hSpCas9	negative selection	9714902
48233378	48233401	13	+	27869803	PATU8988S	viability after 35 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	0.33481480451162193	[254]	[141,116,NaN]	4	hSpCas9	negative selection	9797348
48233406	48233429	13	+	27869803	PATU8988S	viability after 35 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.05318541457202508	[943]	[382,405,NaN]	0	hSpCas9	negative selection	9797349
48233458	48233481	13	-	27869803	PATU8988S	viability after 35 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.47019380073222095	[615]	[218,138,NaN]	-5	hSpCas9	negative selection	9797350
48256252	48256275	13	-	27869803	PATU8988S	viability after 35 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	-0.5471711161869499	[224]	[68,54,NaN]	-5	hSpCas9	negative selection	9797351
48233378	48233401	13	+	27869803	PATU8988S	viability after 31 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	0.3807643446181066	[254]	[83,193,NaN]	4	hSpCas9	negative selection	9879797
48233406	48233429	13	+	27869803	PATU8988S	viability after 31 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	-0.1505133781425685	[943]	[350,323,NaN]	-2	hSpCas9	negative selection	9879798
48233458	48233481	13	-	27869803	PATU8988S	viability after 31 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	-0.6844932238458349	[615]	[125,186,NaN]	-6	hSpCas9	negative selection	9879799
48256252	48256275	13	-	27869803	PATU8988S	viability after 31 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	-0.45346652560742373	[224]	[61,69,NaN]	-5	hSpCas9	negative selection	9879800
48233378	48233401	13	+	27869803	HPAFII	viability after 35 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	1.9979854319727632	[93]	[357,0,NaN]	9	hSpCas9	negative selection	9962246
48233406	48233429	13	+	27869803	HPAFII	viability after 35 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.759219288566599	[302]	[221,301,NaN]	5	hSpCas9	negative selection	9962247
48233458	48233481	13	-	27869803	HPAFII	viability after 35 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.2134950561493007	[239]	[130,151,NaN]	1	hSpCas9	negative selection	9962248
48256252	48256275	13	-	27869803	HPAFII	viability after 35 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	0.6652834681751458	[124]	[105,93,NaN]	4	hSpCas9	negative selection	9962249
48233378	48233401	13	+	27869803	HPAFII	viability after 31 days	CAACTCCGCTCTGGCCCAGAAGG	ITM2B	ENSG00000136156	1.71406565584827	[93]	[319,12,NaN]	9	hSpCas9	negative selection	10044695
48233406	48233429	13	+	27869803	HPAFII	viability after 31 days	AAGAAGGACGAGCCCAAGAGCGG	ITM2B	ENSG00000136156	0.43541841693484895	[302]	[161,303,NaN]	3	hSpCas9	negative selection	10044696
48233458	48233481	13	-	27869803	HPAFII	viability after 31 days	GACCTTGCAGTCCACCGCGACGG	ITM2B	ENSG00000136156	0.7472522081893919	[239]	[216,235,NaN]	5	hSpCas9	negative selection	10044697
48256252	48256275	13	-	27869803	HPAFII	viability after 31 days	ATTGTCTGGTAGAGAGCAGCTGG	ITM2B	ENSG00000136156	1.0953059903331883	[124]	[124,176,NaN]	7	hSpCas9	negative selection	10044698
48233411	48233434	13	+	28162770	P31FUJ	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.0007884235269331463	[164]	[193]	0	hSpCas9	negative selection	10176452
48256177	48256200	13	+	28162770	P31FUJ	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.23407422638408315	[491]	[679]	2	hSpCas9	negative selection	10176453
48256237	48256260	13	-	28162770	P31FUJ	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	-0.0177893134435283	[167]	[194]	0	hSpCas9	negative selection	10176454
48256250	48256273	13	-	28162770	P31FUJ	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	-0.057618740870174934	[425]	[480]	0	hSpCas9	negative selection	10176455
48233359	48233382	13	-	28162770	P31FUJ	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	-0.4435364205664517	[492]	[425]	-4	hSpCas9	negative selection	10176456
48253827	48253850	13	+	28162770	P31FUJ	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	-0.10274166385000583	[105]	[115]	-1	hSpCas9	negative selection	10176457
48253845	48253868	13	-	28162770	P31FUJ	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	-0.20758591880554167	[396]	[403]	-2	hSpCas9	negative selection	10176458
48258152	48258175	13	-	28162770	P31FUJ	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	-0.09967712117501792	[299]	[328]	-1	hSpCas9	negative selection	10176459
48233452	48233475	13	-	28162770	P31FUJ	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	0.6783885286277653	[66]	[125]	7	hSpCas9	negative selection	10176460
48253811	48253834	13	+	28162770	P31FUJ	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	-0.31841091992321546	[242]	[228]	-3	hSpCas9	negative selection	10176461
48233411	48233434	13	+	28162770	TF1	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	NaN	[NaN]	[148]	1	hSpCas9	negative selection	10345818
48256177	48256200	13	+	28162770	TF1	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	NaN	[NaN]	[432]	1	hSpCas9	negative selection	10345819
48256237	48256260	13	-	28162770	TF1	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	NaN	[NaN]	[295]	1	hSpCas9	negative selection	10345820
48256250	48256273	13	-	28162770	TF1	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	NaN	[NaN]	[525]	1	hSpCas9	negative selection	10345821
48233359	48233382	13	-	28162770	TF1	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	NaN	[NaN]	[366]	1	hSpCas9	negative selection	10345822
48253827	48253850	13	+	28162770	TF1	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10345823
48253845	48253868	13	-	28162770	TF1	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	NaN	[NaN]	[503]	1	hSpCas9	negative selection	10345824
48258152	48258175	13	-	28162770	TF1	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	NaN	[NaN]	[397]	1	hSpCas9	negative selection	10345825
48233452	48233475	13	-	28162770	TF1	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	NaN	[NaN]	[47]	1	hSpCas9	negative selection	10345826
48253811	48253834	13	+	28162770	TF1	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10345827
48233411	48233434	13	+	28162770	SKM1	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	1.3155018257279292	[39]	[175]	9	hSpCas9	negative selection	10515184
48256177	48256200	13	+	28162770	SKM1	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.4648794497661559	[99]	[243]	4	hSpCas9	negative selection	10515185
48256237	48256260	13	-	28162770	SKM1	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	0.9819705846409466	[60]	[212]	8	hSpCas9	negative selection	10515186
48256250	48256273	13	-	28162770	SKM1	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.38444917944542056	[116]	[269]	4	hSpCas9	negative selection	10515187
48233359	48233382	13	-	28162770	SKM1	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	-0.023960527104031182	[110]	[192]	0	hSpCas9	negative selection	10515188
48253827	48253850	13	+	28162770	SKM1	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	0.09226842795211065	[25]	[48]	0	hSpCas9	negative selection	10515189
48253845	48253868	13	-	28162770	SKM1	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	0.7905730339070107	[68]	[210]	7	hSpCas9	negative selection	10515190
48258152	48258175	13	-	28162770	SKM1	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	0.3948096910511428	[73]	[171]	4	hSpCas9	negative selection	10515191
48233452	48233475	13	-	28162770	SKM1	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	0.9853532240355987	[13]	[48]	8	hSpCas9	negative selection	10515192
48253811	48253834	13	+	28162770	SKM1	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	0.7140512022182042	[39]	[115]	7	hSpCas9	negative selection	10515193
48233411	48233434	13	+	28162770	SKM1	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	1.3155018257279292	[39]	[175]	9	hSpCas9	negative selection	10684550
48256177	48256200	13	+	28162770	SKM1	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.4648794497661559	[99]	[243]	4	hSpCas9	negative selection	10684551
48256237	48256260	13	-	28162770	SKM1	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	0.9819705846409466	[60]	[212]	8	hSpCas9	negative selection	10684552
48256250	48256273	13	-	28162770	SKM1	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.38444917944542056	[116]	[269]	4	hSpCas9	negative selection	10684553
48233359	48233382	13	-	28162770	SKM1	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	-0.023960527104031182	[110]	[192]	0	hSpCas9	negative selection	10684554
48253827	48253850	13	+	28162770	SKM1	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	0.09226842795211065	[25]	[48]	0	hSpCas9	negative selection	10684555
48253845	48253868	13	-	28162770	SKM1	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	0.7905730339070107	[68]	[210]	7	hSpCas9	negative selection	10684556
48258152	48258175	13	-	28162770	SKM1	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	0.3948096910511428	[73]	[171]	4	hSpCas9	negative selection	10684557
48233452	48233475	13	-	28162770	SKM1	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	0.9853532240355987	[13]	[48]	8	hSpCas9	negative selection	10684558
48253811	48253834	13	+	28162770	SKM1	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	0.7140512022182042	[39]	[115]	7	hSpCas9	negative selection	10684559
48233411	48233434	13	+	28162770	PL21	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	1.2763752003164055	[128]	[135]	9	hSpCas9	negative selection	10853916
48256177	48256200	13	+	28162770	PL21	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.7718052925970185	[326]	[242]	6	hSpCas9	negative selection	10853917
48256237	48256260	13	-	28162770	PL21	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	0.9936887370218935	[194]	[168]	8	hSpCas9	negative selection	10853918
48256250	48256273	13	-	28162770	PL21	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	-0.30964849577506126	[429]	[150]	-2	hSpCas9	negative selection	10853919
48233359	48233382	13	-	28162770	PL21	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	0.2880467036387476	[381]	[202]	2	hSpCas9	negative selection	10853920
48253827	48253850	13	+	28162770	PL21	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	0.5775066958021089	[96]	[62]	5	hSpCas9	negative selection	10853921
48253845	48253868	13	-	28162770	PL21	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	-0.5976715348974129	[225]	[64]	-4	hSpCas9	negative selection	10853922
48258152	48258175	13	-	28162770	PL21	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	0.8799613015519174	[205]	[164]	7	hSpCas9	negative selection	10853923
48233452	48233475	13	-	28162770	PL21	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	-0.9962575983141835	[54]	[11]	-6	hSpCas9	negative selection	10853924
48253811	48253834	13	+	28162770	PL21	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	0.5889931819645089	[138]	[90]	5	hSpCas9	negative selection	10853925
48233411	48233434	13	+	28162770	P31FUJ	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.0007884235269331463	[164]	[193]	0	hSpCas9	negative selection	11023282
48256177	48256200	13	+	28162770	P31FUJ	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.23407422638408315	[491]	[679]	2	hSpCas9	negative selection	11023283
48256237	48256260	13	-	28162770	P31FUJ	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	-0.0177893134435283	[167]	[194]	0	hSpCas9	negative selection	11023284
48256250	48256273	13	-	28162770	P31FUJ	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	-0.057618740870174934	[425]	[480]	0	hSpCas9	negative selection	11023285
48233359	48233382	13	-	28162770	P31FUJ	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	-0.4435364205664517	[492]	[425]	-4	hSpCas9	negative selection	11023286
48253827	48253850	13	+	28162770	P31FUJ	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	-0.10274166385000583	[105]	[115]	-1	hSpCas9	negative selection	11023287
48253845	48253868	13	-	28162770	P31FUJ	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	-0.20758591880554167	[396]	[403]	-2	hSpCas9	negative selection	11023288
48258152	48258175	13	-	28162770	P31FUJ	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	-0.09967712117501792	[299]	[328]	-1	hSpCas9	negative selection	11023289
48233452	48233475	13	-	28162770	P31FUJ	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	0.6783885286277653	[66]	[125]	7	hSpCas9	negative selection	11023290
48253811	48253834	13	+	28162770	P31FUJ	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	-0.31841091992321546	[242]	[228]	-3	hSpCas9	negative selection	11023291
48233411	48233434	13	+	28162770	OCIAML5	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.5410055969180552	[90]	[238]	5	hSpCas9	negative selection	11192648
48256177	48256200	13	+	28162770	OCIAML5	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.14793342913600283	[265]	[531]	1	hSpCas9	negative selection	11192649
48256237	48256260	13	-	28162770	OCIAML5	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	0.4437880124134721	[133]	[328]	4	hSpCas9	negative selection	11192650
48256250	48256273	13	-	28162770	OCIAML5	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.5269916313092801	[202]	[527]	4	hSpCas9	negative selection	11192651
48233359	48233382	13	-	28162770	OCIAML5	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	0.3260977164842336	[193]	[438]	2	hSpCas9	negative selection	11192652
48253827	48253850	13	+	28162770	OCIAML5	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	-0.21979835536448422	[39]	[61]	-2	hSpCas9	negative selection	11192653
48253845	48253868	13	-	28162770	OCIAML5	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	1.3490733012438545	[126]	[583]	9	hSpCas9	negative selection	11192654
48258152	48258175	13	-	28162770	OCIAML5	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	0.004143642538636749	[252]	[457]	0	hSpCas9	negative selection	11192655
48233452	48233475	13	-	28162770	OCIAML5	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	-0.6296741495275491	[23]	[27]	-4	hSpCas9	negative selection	11192656
48253811	48253834	13	+	28162770	OCIAML5	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	1.251163586244659	[90]	[390]	9	hSpCas9	negative selection	11192657
48233411	48233434	13	+	28162770	EOL1	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.8705079318576454	[271]	[261]	7	hSpCas9	negative selection	11362014
48256177	48256200	13	+	28162770	EOL1	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.6016410197254551	[480]	[166]	-4	hSpCas9	negative selection	11362015
48256237	48256260	13	-	28162770	EOL1	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	0.5889447397860957	[370]	[293]	5	hSpCas9	negative selection	11362016
48256250	48256273	13	-	28162770	EOL1	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.2269774577810022	[878]	[541]	2	hSpCas9	negative selection	11362017
48233359	48233382	13	-	28162770	EOL1	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	0.23463425381338054	[733]	[454]	2	hSpCas9	negative selection	11362018
48253827	48253850	13	+	28162770	EOL1	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	-0.4221027527280591	[205]	[80]	-3	hSpCas9	negative selection	11362019
48253845	48253868	13	-	28162770	EOL1	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	0.0719781352257604	[315]	[174]	0	hSpCas9	negative selection	11362020
48258152	48258175	13	-	28162770	EOL1	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	0.692024669953389	[261]	[222]	6	hSpCas9	negative selection	11362021
48233452	48233475	13	-	28162770	EOL1	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	-0.721815273814765	[71]	[22]	-5	hSpCas9	negative selection	11362022
48253811	48253834	13	+	28162770	EOL1	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	0.16555587107432942	[241]	[142]	1	hSpCas9	negative selection	11362023
48233411	48233434	13	+	28162770	MOLM13	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.9200966734139634	[181]	[248]	7	hSpCas9	negative selection	11531380
48256177	48256200	13	+	28162770	MOLM13	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.6428324577535158	[573]	[647]	5	hSpCas9	negative selection	11531381
48256237	48256260	13	-	28162770	MOLM13	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	0.15429714582528087	[301]	[242]	1	hSpCas9	negative selection	11531382
48256250	48256273	13	-	28162770	MOLM13	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.5953791166664943	[551]	[602]	4	hSpCas9	negative selection	11531383
48233359	48233382	13	-	28162770	MOLM13	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	0.2512533570356814	[666]	[573]	1	hSpCas9	negative selection	11531384
48253827	48253850	13	+	28162770	MOLM13	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	0.5735988227156941	[170]	[183]	4	hSpCas9	negative selection	11531385
48253845	48253868	13	-	28162770	MOLM13	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	0.5302681666962655	[429]	[448]	4	hSpCas9	negative selection	11531386
48258152	48258175	13	-	28162770	MOLM13	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	-0.02325109682005655	[505]	[359]	0	hSpCas9	negative selection	11531387
48233452	48233475	13	-	28162770	MOLM13	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	-0.32218754908118963	[82]	[47]	-2	hSpCas9	negative selection	11531388
48253811	48253834	13	+	28162770	MOLM13	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	-1.0227457366284243	[221]	[78]	-5	hSpCas9	negative selection	11531389
48233411	48233434	13	+	28162770	HEL	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.5964451797264217	[189]	[183]	5	hSpCas9	negative selection	11700746
48256177	48256200	13	+	28162770	HEL	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	-0.8884916847830097	[447]	[154]	-5	hSpCas9	negative selection	11700747
48256237	48256260	13	-	28162770	HEL	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	0.07242310724360201	[244]	[164]	0	hSpCas9	negative selection	11700748
48256250	48256273	13	-	28162770	HEL	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.7147024275202898	[566]	[595]	6	hSpCas9	negative selection	11700749
48233359	48233382	13	-	28162770	HEL	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	1.0418577308511654	[523]	[690]	8	hSpCas9	negative selection	11700750
48253827	48253850	13	+	28162770	HEL	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	0.4700994458610086	[132]	[117]	4	hSpCas9	negative selection	11700751
48253845	48253868	13	-	28162770	HEL	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	0.3427532899936715	[260]	[211]	3	hSpCas9	negative selection	11700752
48258152	48258175	13	-	28162770	HEL	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	0.40924870178057837	[347]	[295]	3	hSpCas9	negative selection	11700753
48233452	48233475	13	-	28162770	HEL	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	0.4958974436710859	[61]	[55]	4	hSpCas9	negative selection	11700754
48253811	48253834	13	+	28162770	HEL	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	1.201033382259433	[181]	[267]	9	hSpCas9	negative selection	11700755
48233411	48233434	13	+	28162770	MV411	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.3033939567567906	[176]	[183]	2	hSpCas9	negative selection	11870112
48256177	48256200	13	+	28162770	MV411	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.48069670566690925	[358]	[421]	4	hSpCas9	negative selection	11870113
48256237	48256260	13	-	28162770	MV411	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	0.12317944782062934	[205]	[188]	1	hSpCas9	negative selection	11870114
48256250	48256273	13	-	28162770	MV411	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.5790257567207073	[386]	[486]	5	hSpCas9	negative selection	11870115
48233359	48233382	13	-	28162770	MV411	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	0.11101835255618009	[398]	[362]	0	hSpCas9	negative selection	11870116
48253827	48253850	13	+	28162770	MV411	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	0.8568530952284705	[77]	[118]	7	hSpCas9	negative selection	11870117
48253845	48253868	13	-	28162770	MV411	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	0.3568886931987726	[202]	[218]	3	hSpCas9	negative selection	11870118
48258152	48258175	13	-	28162770	MV411	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	0.568224724265568	[252]	[315]	5	hSpCas9	negative selection	11870119
48233452	48233475	13	-	28162770	MV411	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	-1.60671158275377	[46]	[12]	-7	hSpCas9	negative selection	11870120
48253811	48253834	13	+	28162770	MV411	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	-0.3375249499383809	[119]	[79]	-3	hSpCas9	negative selection	11870121
48233411	48233434	13	+	28162770	MONOMAC1	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	0.053771256440980575	[78]	[93]	0	hSpCas9	negative selection	12039478
48256177	48256200	13	+	28162770	MONOMAC1	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.38172050413489433	[232]	[347]	4	hSpCas9	negative selection	12039479
48256237	48256260	13	-	28162770	MONOMAC1	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	-0.5418653440569947	[126]	[99]	-4	hSpCas9	negative selection	12039480
48256250	48256273	13	-	28162770	MONOMAC1	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.7214332674438477	[272]	[515]	7	hSpCas9	negative selection	12039481
48233359	48233382	13	-	28162770	MONOMAC1	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	-0.7181528657560838	[220]	[153]	-5	hSpCas9	negative selection	12039482
48253827	48253850	13	+	28162770	MONOMAC1	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	-0.06377031619608942	[61]	[67]	0	hSpCas9	negative selection	12039483
48253845	48253868	13	-	28162770	MONOMAC1	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	-0.07478109700855556	[146]	[159]	0	hSpCas9	negative selection	12039484
48258152	48258175	13	-	28162770	MONOMAC1	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	0.8857035839483826	[143]	[304]	7	hSpCas9	negative selection	12039485
48233452	48233475	13	-	28162770	MONOMAC1	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	2.5489175303339073	[23]	[160]	9	hSpCas9	negative selection	12039486
48253811	48253834	13	+	28162770	MONOMAC1	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	-1.331966427145662	[111]	[50]	-7	hSpCas9	negative selection	12039487
48233411	48233434	13	+	28162770	OCIAML2	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	-0.3096379485698564	[35]	[160]	-3	hSpCas9	negative selection	12208844
48256177	48256200	13	+	28162770	OCIAML2	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	0.14995658520971633	[59]	[368]	1	hSpCas9	negative selection	12208845
48256237	48256260	13	-	28162770	OCIAML2	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	-0.17517394171598988	[43]	[215]	-1	hSpCas9	negative selection	12208846
48256250	48256273	13	-	28162770	OCIAML2	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.42211658804608754	[81]	[608]	4	hSpCas9	negative selection	12208847
48233359	48233382	13	-	28162770	OCIAML2	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	0.3333970790976887	[61]	[432]	3	hSpCas9	negative selection	12208848
48253827	48253850	13	+	28162770	OCIAML2	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	-0.046131996714251056	[18]	[101]	0	hSpCas9	negative selection	12208849
48253845	48253868	13	-	28162770	OCIAML2	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	0.8952759667058036	[41]	[432]	8	hSpCas9	negative selection	12208850
48258152	48258175	13	-	28162770	OCIAML2	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	-0.2689959640725107	[49]	[229]	-2	hSpCas9	negative selection	12208851
48233452	48233475	13	-	28162770	OCIAML2	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	0.9216875975365992	[5]	[62]	8	hSpCas9	negative selection	12208852
48253811	48253834	13	+	28162770	OCIAML2	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	1.875145011599569	[11]	[243]	9	hSpCas9	negative selection	12208853
48233411	48233434	13	+	28162770	OCIAML3	viability	GGACGAGCCCAAGAGCGGCGAGG	ITM2B	ENSG00000136156	-1.8350157398279578	[38]	[32]	-8	hSpCas9	negative selection	12378210
48256177	48256200	13	+	28162770	OCIAML3	viability	CCAGATGACGTGTACTACTGTGG	ITM2B	ENSG00000136156	1.4124763932460356	[110]	[891]	9	hSpCas9	negative selection	12378211
48256237	48256260	13	-	28162770	OCIAML3	viability	GCAGCTGGGGCATCTGCAGAGGG	ITM2B	ENSG00000136156	0.6928735074639983	[49]	[243]	6	hSpCas9	negative selection	12378212
48256250	48256273	13	-	28162770	OCIAML3	viability	TGTCTGGTAGAGAGCAGCTGGGG	ITM2B	ENSG00000136156	0.42621063909448864	[123]	[502]	4	hSpCas9	negative selection	12378213
48233359	48233382	13	-	28162770	OCIAML3	viability	GTTGAACGTCACCTTCACCATGG	ITM2B	ENSG00000136156	0.20282940981944164	[117]	[409]	2	hSpCas9	negative selection	12378214
48253827	48253850	13	+	28162770	OCIAML3	viability	CAGTTGGCCAAAGAAGAGCCTGG	ITM2B	ENSG00000136156	0.0888021837951376	[18]	[60]	0	hSpCas9	negative selection	12378215
48253845	48253868	13	-	28162770	OCIAML3	viability	AAAGCACATGCACCAACACCAGG	ITM2B	ENSG00000136156	0.5041727536147402	[70]	[303]	5	hSpCas9	negative selection	12378216
48258152	48258175	13	-	28162770	OCIAML3	viability	GGATCACATAGCACTTATCCAGG	ITM2B	ENSG00000136156	-0.15526588045405093	[82]	[224]	-1	hSpCas9	negative selection	12378217
48233452	48233475	13	-	28162770	OCIAML3	viability	GCAGTCCACCGCGACGGCGTCGG	ITM2B	ENSG00000136156	0.4334730960979438	[12]	[52]	4	hSpCas9	negative selection	12378218
48253811	48253834	13	+	28162770	OCIAML3	viability	CCAGATGATGTGGTACCAGTTGG	ITM2B	ENSG00000136156	1.3377576239233848	[45]	[350]	9	hSpCas9	negative selection	12378219