Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 3708
• Symbol: ITPR1
• Description: inositol 1,4,5-trisphosphate receptor type 1

DataSource: http://genomecrispr.dkfz.de/#!/results/ITPR1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
4768716	4768739	3	-	26472758	Jiyoye	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-0.31271669930139145	[27]	[16]	-2	hSpCas9	negative selection	79993
4683402	4683425	3	+	26472758	Jiyoye	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	1.3527275974834971	[80]	[155]	7	hSpCas9	negative selection	79994
4642164	4642187	3	+	26472758	Jiyoye	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	0.3724099633451967	[41]	[40]	3	hSpCas9	negative selection	79995
4644165	4644188	3	-	26472758	Jiyoye	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	0.7797295494632037	[111]	[144]	5	hSpCas9	negative selection	79996
4658238	4658261	3	+	26472758	Jiyoye	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	-0.10221134460854975	[594]	[417]	0	hSpCas9	negative selection	79997
4665188	4665211	3	+	26472758	Jiyoye	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	0.5291659058844838	[101]	[110]	4	hSpCas9	negative selection	79998
4667495	4667518	3	-	26472758	Jiyoye	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	1.9921378822270288	[0]	[2]	8	hSpCas9	negative selection	79999
4673280	4673303	3	-	26472758	Jiyoye	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	0.2696718577559385	[54]	[49]	2	hSpCas9	negative selection	80000
4673346	4673369	3	-	26472758	Jiyoye	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	-0.16619914494007088	[185]	[124]	-1	hSpCas9	negative selection	80001
4676729	4676752	3	+	26472758	Jiyoye	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	0.8045108790512585	[40]	[53]	5	hSpCas9	negative selection	80002
4768716	4768739	3	-	26472758	KBM7	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-0.2821327398255702	[340,104]	[138,30]	-3	hSpCas9	negative selection	271111
4683402	4683425	3	+	26472758	KBM7	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	0.6805776146965914	[518,408]	[202,475]	7	hSpCas9	negative selection	271112
4642164	4642187	3	+	26472758	KBM7	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	0.3068998114964374	[111,137]	[76,70]	3	hSpCas9	negative selection	271113
4644165	4644188	3	-	26472758	KBM7	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	-0.12887533780875263	[491,450]	[205,199]	-1	hSpCas9	negative selection	271114
4658238	4658261	3	+	26472758	KBM7	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	0.3457183430940127	[2125,1640]	[1435,829]	3	hSpCas9	negative selection	271115
4665188	4665211	3	+	26472758	KBM7	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	0.13752227149939134	[332,268]	[168,141]	1	hSpCas9	negative selection	271116
4667495	4667518	3	-	26472758	KBM7	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	1.083213413722325	[17,22]	[24,16]	9	hSpCas9	negative selection	271117
4673280	4673303	3	-	26472758	KBM7	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-1.1971554541671003	[352,308]	[81,54]	-7	hSpCas9	negative selection	271118
4673346	4673369	3	-	26472758	KBM7	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	0.6272436042710936	[549,422]	[296,397]	7	hSpCas9	negative selection	271119
4676729	4676752	3	+	26472758	KBM7	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	-0.9232636641116704	[549,576]	[107,169]	-6	hSpCas9	negative selection	271120
4768716	4768739	3	-	26472758	Raji	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-0.6333736379549808	[126]	[18]	-5	hSpCas9	negative selection	462229
4683402	4683425	3	+	26472758	Raji	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	-0.5009618927855075	[310]	[50]	-4	hSpCas9	negative selection	462230
4642164	4642187	3	+	26472758	Raji	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	-0.21454455951376294	[79]	[15]	-2	hSpCas9	negative selection	462231
4644165	4644188	3	-	26472758	Raji	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	0.31152425215382484	[124]	[35]	3	hSpCas9	negative selection	462232
4658238	4658261	3	+	26472758	Raji	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	0.5548425123448206	[747]	[254]	5	hSpCas9	negative selection	462233
4665188	4665211	3	+	26472758	Raji	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	3.21780752506725	[43]	[94]	9	hSpCas9	negative selection	462234
4667495	4667518	3	-	26472758	Raji	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	-0.8926164646264003	[39]	[4]	-6	hSpCas9	negative selection	462235
4673280	4673303	3	-	26472758	Raji	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	0.2829550999570538	[84]	[23]	2	hSpCas9	negative selection	462236
4673346	4673369	3	-	26472758	Raji	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	-0.3711569062114025	[417]	[74]	-3	hSpCas9	negative selection	462237
4676729	4676752	3	+	26472758	Raji	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	-0.9215678383225296	[301]	[36]	-6	hSpCas9	negative selection	462238
4768716	4768739	3	-	26472758	K562	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-0.47354590456970347	[175]	[106]	-3	hSpCas9	negative selection	653347
4683402	4683425	3	+	26472758	K562	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	0.3742369681534038	[307]	[336]	3	hSpCas9	negative selection	653348
4642164	4642187	3	+	26472758	K562	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	2.4394347100715894	[37]	[173]	9	hSpCas9	negative selection	653349
4644165	4644188	3	-	26472758	K562	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	-0.22506655563477337	[377]	[272]	-1	hSpCas9	negative selection	653350
4658238	4658261	3	+	26472758	K562	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	0.2840481032335487	[1543]	[1586]	2	hSpCas9	negative selection	653351
4665188	4665211	3	+	26472758	K562	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	-0.3770696490798233	[239]	[155]	-2	hSpCas9	negative selection	653352
4667495	4667518	3	-	26472758	K562	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	-3.5104687744970215	[26]	[1]	-8	hSpCas9	negative selection	653353
4673280	4673303	3	-	26472758	K562	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-2.2567121822512384	[350]	[61]	-7	hSpCas9	negative selection	653354
4673346	4673369	3	-	26472758	K562	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	-0.4957671692674017	[597]	[357]	-3	hSpCas9	negative selection	653355
4676729	4676752	3	+	26472758	K562	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	-2.0534861380143994	[535]	[108]	-7	hSpCas9	negative selection	653356
4516543	4516566	3	+	26627737	DLD1	viability	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.007580473757599737	[1035]	[312,284,369]	0	hSpCas9	negative selection	821844
4521024	4521047	3	-	26627737	DLD1	viability	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	0.6988740122768129	[967]	[504,680,321]	7	hSpCas9	negative selection	821845
4627813	4627836	3	+	26627737	DLD1	viability	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.07886644124307574	[562]	[240,185,137]	0	hSpCas9	negative selection	821916
4642219	4642242	3	-	26627737	DLD1	viability	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	0.5983738057061958	[530]	[207,203,327]	6	hSpCas9	negative selection	821946
4644202	4644225	3	+	26627737	DLD1	viability	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	0.3851996721603358	[693]	[298,247,298]	4	hSpCas9	negative selection	821947
4645394	4645417	3	+	26627737	DLD1	viability	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	1.6923618988796507	[455]	[308,740,359]	9	hSpCas9	negative selection	821948
4516543	4516566	3	+	26627737	GBM cells	viability after 5 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.4577871467381811	[464]	[306,377]	7	hSpCas9	negative selection	904159
4521024	4521047	3	-	26627737	GBM cells	viability after 5 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.23056264954275618	[698]	[317,320]	-4	hSpCas9	negative selection	904160
4627813	4627836	3	+	26627737	GBM cells	viability after 5 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.5776011329788142	[292]	[236,231]	8	hSpCas9	negative selection	904231
4642219	4642242	3	-	26627737	GBM cells	viability after 5 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	0.6899989574667782	[292]	[247,258]	8	hSpCas9	negative selection	904261
4644202	4644225	3	+	26627737	GBM cells	viability after 5 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-0.3254400627840486	[367]	[213,100]	-5	hSpCas9	negative selection	904262
4645394	4645417	3	+	26627737	GBM cells	viability after 5 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	0.15123226634854947	[517]	[264,351]	2	hSpCas9	negative selection	904263
4516543	4516566	3	+	26627737	GBM cells	viability after 13 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.3658342735468756	[464]	[355,299]	5	hSpCas9	negative selection	986474
4521024	4521047	3	-	26627737	GBM cells	viability after 13 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.1457541444993029	[698]	[392,301]	-2	hSpCas9	negative selection	986475
4627813	4627836	3	+	26627737	GBM cells	viability after 13 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.7294079472436383	[292]	[310,224]	8	hSpCas9	negative selection	986546
4642219	4642242	3	-	26627737	GBM cells	viability after 13 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	0.8534724216455001	[292]	[364,223]	8	hSpCas9	negative selection	986576
4644202	4644225	3	+	26627737	GBM cells	viability after 13 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-0.34643273728385837	[367]	[177,139]	-4	hSpCas9	negative selection	986577
4645394	4645417	3	+	26627737	GBM cells	viability after 13 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	0.34471848268005023	[517]	[389,329]	4	hSpCas9	negative selection	986578
4516543	4516566	3	+	26627737	GBM cells	viability after 21 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.5298446383943258	[464]	[370,358]	5	hSpCas9	negative selection	1068789
4521024	4521047	3	-	26627737	GBM cells	viability after 21 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.17707508357438306	[698]	[361,311]	-2	hSpCas9	negative selection	1068790
4627813	4627836	3	+	26627737	GBM cells	viability after 21 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.9422355256007169	[292]	[308,302]	8	hSpCas9	negative selection	1068861
4642219	4642242	3	-	26627737	GBM cells	viability after 21 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	0.6531190061649976	[292]	[277,224]	6	hSpCas9	negative selection	1068891
4644202	4644225	3	+	26627737	GBM cells	viability after 21 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-0.9424266101306629	[367]	[114,93]	-7	hSpCas9	negative selection	1068892
4645394	4645417	3	+	26627737	GBM cells	viability after 21 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	0.9034711424785855	[517]	[551,502]	8	hSpCas9	negative selection	1068893
4516543	4516566	3	+	26627737	RPE1	viability after 9 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	1.6708893936925062	[785]	[731,849]	8	hSpCas9	negative selection	1151104
4521024	4521047	3	-	26627737	RPE1	viability after 9 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.17530263738285679	[2114]	[650,502]	-1	hSpCas9	negative selection	1151105
4627813	4627836	3	+	26627737	RPE1	viability after 9 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.5866895189318525	[1505]	[804,582]	4	hSpCas9	negative selection	1151176
4642219	4642242	3	-	26627737	RPE1	viability after 9 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	2.2266014571208292	[449]	[437,944]	9	hSpCas9	negative selection	1151206
4644202	4644225	3	+	26627737	RPE1	viability after 9 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-0.2996356601870087	[1569]	[287,542]	-2	hSpCas9	negative selection	1151207
4645394	4645417	3	+	26627737	RPE1	viability after 9 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	1.774644348041587	[801]	[652,1124]	8	hSpCas9	negative selection	1151208
4516543	4516566	3	+	26627737	RPE1	viability after 12 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	1.686934981773911	[785]	[744,610]	8	hSpCas9	negative selection	1233419
4521024	4521047	3	-	26627737	RPE1	viability after 12 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.13551299691560081	[2114]	[611,416]	-1	hSpCas9	negative selection	1233420
4627813	4627836	3	+	26627737	RPE1	viability after 12 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.7213336929384823	[1505]	[618,717]	4	hSpCas9	negative selection	1233491
4642219	4642242	3	-	26627737	RPE1	viability after 12 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	2.4207801045268966	[449]	[523,777]	9	hSpCas9	negative selection	1233521
4644202	4644225	3	+	26627737	RPE1	viability after 12 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-0.510844816919254	[1569]	[262,330]	-4	hSpCas9	negative selection	1233522
4645394	4645417	3	+	26627737	RPE1	viability after 12 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	1.6666862776296811	[801]	[635,734]	8	hSpCas9	negative selection	1233523
4516543	4516566	3	+	26627737	RPE1	viability after 15 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	1.5721512714894121	[785]	[681,640]	8	hSpCas9	negative selection	1315734
4521024	4521047	3	-	26627737	RPE1	viability after 15 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.2504017824467355	[2114]	[420,581]	-1	hSpCas9	negative selection	1315735
4627813	4627836	3	+	26627737	RPE1	viability after 15 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.5676077773971336	[1505]	[609,651]	3	hSpCas9	negative selection	1315806
4642219	4642242	3	-	26627737	RPE1	viability after 15 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	2.2458913858035463	[449]	[586,619]	9	hSpCas9	negative selection	1315836
4644202	4644225	3	+	26627737	RPE1	viability after 15 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-0.08630122506564808	[1569]	[455,381]	0	hSpCas9	negative selection	1315837
4645394	4645417	3	+	26627737	RPE1	viability after 15 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	1.796396113846983	[801]	[476,1087]	8	hSpCas9	negative selection	1315838
4516543	4516566	3	+	26627737	RPE1	viability after 18 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	1.5180852575503263	[785]	[651,559]	7	hSpCas9	negative selection	1398049
4521024	4521047	3	-	26627737	RPE1	viability after 18 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	0.2642341806887951	[2114]	[699,669]	1	hSpCas9	negative selection	1398050
4627813	4627836	3	+	26627737	RPE1	viability after 18 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.5348680620625258	[1505]	[510,671]	3	hSpCas9	negative selection	1398121
4642219	4642242	3	-	26627737	RPE1	viability after 18 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	2.4015388831117974	[449]	[412,885]	9	hSpCas9	negative selection	1398151
4644202	4644225	3	+	26627737	RPE1	viability after 18 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-0.06919384965206155	[1569]	[384,423]	0	hSpCas9	negative selection	1398152
4645394	4645417	3	+	26627737	RPE1	viability after 18 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	1.7442733428832087	[801]	[640,814]	8	hSpCas9	negative selection	1398153
4516543	4516566	3	+	26627737	HeLa	viability after 8 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	-0.06902209710246454	[752]	[463,335,179]	0	hSpCas9	negative selection	1480364
4521024	4521047	3	-	26627737	HeLa	viability after 8 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.3074847226903459	[1247]	[428,486,400]	-3	hSpCas9	negative selection	1480365
4627813	4627836	3	+	26627737	HeLa	viability after 8 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.6265775162511742	[303]	[182,190,231]	5	hSpCas9	negative selection	1480436
4642219	4642242	3	-	26627737	HeLa	viability after 8 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	-1.4842329500557268	[1024]	[174,136,168]	-9	hSpCas9	negative selection	1480466
4644202	4644225	3	+	26627737	HeLa	viability after 8 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-1.2327602515354714	[1023]	[306,236,59]	-8	hSpCas9	negative selection	1480467
4645394	4645417	3	+	26627737	HeLa	viability after 8 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	1.0672655613097706	[661]	[673,528,621]	7	hSpCas9	negative selection	1480468
4516543	4516566	3	+	26627737	HeLa	viability after 12 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.1649902597106342	[752]	[538,246,276]	1	hSpCas9	negative selection	1562679
4521024	4521047	3	-	26627737	HeLa	viability after 12 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-1.1324804591671946	[1247]	[226,258,216]	-8	hSpCas9	negative selection	1562680
4627813	4627836	3	+	26627737	HeLa	viability after 12 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	1.2626804484853829	[303]	[342,164,411]	8	hSpCas9	negative selection	1562751
4642219	4642242	3	-	26627737	HeLa	viability after 12 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	-0.7357541898059968	[1024]	[274,279,205]	-6	hSpCas9	negative selection	1562781
4644202	4644225	3	+	26627737	HeLa	viability after 12 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-1.372394649683137	[1023]	[92,156,238]	-8	hSpCas9	negative selection	1562782
4645394	4645417	3	+	26627737	HeLa	viability after 12 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	1.0078816694151569	[661]	[870,453,344]	7	hSpCas9	negative selection	1562783
4516543	4516566	3	+	26627737	HeLa	viability after 15 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.19701494864734725	[752]	[473,258,316]	1	hSpCas9	negative selection	1644994
4521024	4521047	3	-	26627737	HeLa	viability after 15 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.6605115934942452	[1247]	[213,377,377]	-5	hSpCas9	negative selection	1644995
4627813	4627836	3	+	26627737	HeLa	viability after 15 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	1.3300354055781143	[303]	[351,183,403]	8	hSpCas9	negative selection	1645066
4642219	4642242	3	-	26627737	HeLa	viability after 15 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	-0.9305176138958736	[1024]	[241,249,159]	-7	hSpCas9	negative selection	1645096
4644202	4644225	3	+	26627737	HeLa	viability after 15 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-0.7794272664530696	[1023]	[454,110,152]	-6	hSpCas9	negative selection	1645097
4645394	4645417	3	+	26627737	HeLa	viability after 15 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	1.3153805478055811	[661]	[669,841,485]	8	hSpCas9	negative selection	1645098
4516543	4516566	3	+	26627737	HeLa	viability after 18 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.18938471355542685	[752]	[313,214,316]	1	hSpCas9	negative selection	1727309
4521024	4521047	3	-	26627737	HeLa	viability after 18 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.6567829382443466	[1247]	[137,321,377]	-5	hSpCas9	negative selection	1727310
4627813	4627836	3	+	26627737	HeLa	viability after 18 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	1.3544612192372438	[303]	[241,157,403]	8	hSpCas9	negative selection	1727381
4642219	4642242	3	-	26627737	HeLa	viability after 18 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	-0.9002772370495212	[1024]	[160,219,159]	-7	hSpCas9	negative selection	1727411
4644202	4644225	3	+	26627737	HeLa	viability after 18 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-0.7800961680645917	[1023]	[304,91,152]	-6	hSpCas9	negative selection	1727412
4645394	4645417	3	+	26627737	HeLa	viability after 18 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	1.3385200196884899	[661]	[465,702,485]	8	hSpCas9	negative selection	1727413
4516543	4516566	3	+	26627737	HCT116	viability after 6 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.7698734729844732	[1397]	[444,335]	4	hSpCas9	negative selection	1809624
4521024	4521047	3	-	26627737	HCT116	viability after 6 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	0.794737007292952	[2020]	[652,494]	4	hSpCas9	negative selection	1809625
4627813	4627836	3	+	26627737	HCT116	viability after 6 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.4266854461695685	[939]	[148,225]	2	hSpCas9	negative selection	1809696
4642219	4642242	3	-	26627737	HCT116	viability after 6 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	0.0725268703608631	[570]	[134,71]	0	hSpCas9	negative selection	1809726
4644202	4644225	3	+	26627737	HCT116	viability after 6 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-0.07345274462568074	[806]	[175,89]	0	hSpCas9	negative selection	1809727
4645394	4645417	3	+	26627737	HCT116	viability after 6 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	2.243729189236043	[542]	[752,211]	9	hSpCas9	negative selection	1809728
4516543	4516566	3	+	26627737	HCT116	viability after 8 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.4361106859634081	[443]	[415,367,211]	4	hSpCas9	negative selection	1891939
4521024	4521047	3	-	26627737	HCT116	viability after 8 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	0.01290945759269535	[695]	[287,391,477]	0	hSpCas9	negative selection	1891940
4627813	4627836	3	+	26627737	HCT116	viability after 8 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.6908996752967617	[314]	[239,329,269]	6	hSpCas9	negative selection	1892011
4642219	4642242	3	-	26627737	HCT116	viability after 8 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	0.19635854176592327	[313]	[160,227,204]	2	hSpCas9	negative selection	1892041
4644202	4644225	3	+	26627737	HCT116	viability after 8 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	0.21597989430712175	[315]	[180,193,230]	2	hSpCas9	negative selection	1892042
4645394	4645417	3	+	26627737	HCT116	viability after 8 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	0.07203443591081715	[632]	[319,235,540]	0	hSpCas9	negative selection	1892043
4516543	4516566	3	+	26627737	HCT116	viability after 9 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.25373633138628393	[1397]	[472,422]	2	hSpCas9	negative selection	1974254
4521024	4521047	3	-	26627737	HCT116	viability after 9 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	0.4438078722395531	[2020]	[1019,507]	3	hSpCas9	negative selection	1974255
4627813	4627836	3	+	26627737	HCT116	viability after 9 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.26661935743946874	[939]	[497,146]	2	hSpCas9	negative selection	1974326
4642219	4642242	3	-	26627737	HCT116	viability after 9 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	0.4660291880576091	[570]	[56,331]	3	hSpCas9	negative selection	1974356
4644202	4644225	3	+	26627737	HCT116	viability after 9 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	0.09020720638851243	[806]	[239,220]	0	hSpCas9	negative selection	1974357
4645394	4645417	3	+	26627737	HCT116	viability after 9 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	1.679226456369338	[542]	[689,285]	8	hSpCas9	negative selection	1974358
4516543	4516566	3	+	26627737	HCT116	viability after 12 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.6340729290244937	[443]	[344,408,334]	6	hSpCas9	negative selection	2056569
4521024	4521047	3	-	26627737	HCT116	viability after 12 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	0.04048779712901296	[695]	[485,380,251]	0	hSpCas9	negative selection	2056570
4627813	4627836	3	+	26627737	HCT116	viability after 12 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.8047439441155012	[314]	[254,308,306]	7	hSpCas9	negative selection	2056641
4642219	4642242	3	-	26627737	HCT116	viability after 12 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	0.551387242104499	[313]	[165,276,289]	5	hSpCas9	negative selection	2056671
4644202	4644225	3	+	26627737	HCT116	viability after 12 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	0.2397976896032545	[315]	[147,174,268]	2	hSpCas9	negative selection	2056672
4645394	4645417	3	+	26627737	HCT116	viability after 12 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	-0.3275978148560241	[632]	[292,190,306]	-3	hSpCas9	negative selection	2056673
4516543	4516566	3	+	26627737	HCT116	viability after 15 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.7736091321056962	[443]	[425,483,396]	6	hSpCas9	negative selection	2138884
4521024	4521047	3	-	26627737	HCT116	viability after 15 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.034302332966234195	[695]	[401,431,338]	0	hSpCas9	negative selection	2138885
4627813	4627836	3	+	26627737	HCT116	viability after 15 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.6003274380862477	[314]	[346,323,161]	5	hSpCas9	negative selection	2138956
4642219	4642242	3	-	26627737	HCT116	viability after 15 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	0.4446932314332847	[313]	[258,320,158]	4	hSpCas9	negative selection	2138986
4644202	4644225	3	+	26627737	HCT116	viability after 15 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	0.6346521419726009	[315]	[133,221,468]	6	hSpCas9	negative selection	2138987
4645394	4645417	3	+	26627737	HCT116	viability after 15 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	0.3243844558918323	[632]	[589,256,533]	3	hSpCas9	negative selection	2138988
4516543	4516566	3	+	26627737	HCT116	viability after 18 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.9786180882405069	[443]	[457,493,306]	7	hSpCas9	negative selection	2221199
4521024	4521047	3	-	26627737	HCT116	viability after 18 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.17244553329810253	[695]	[267,342,280]	-1	hSpCas9	negative selection	2221200
4627813	4627836	3	+	26627737	HCT116	viability after 18 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.9960697429024928	[314]	[277,401,220]	7	hSpCas9	negative selection	2221271
4642219	4642242	3	-	26627737	HCT116	viability after 18 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	0.5567609326460251	[313]	[235,259,168]	5	hSpCas9	negative selection	2221301
4644202	4644225	3	+	26627737	HCT116	viability after 18 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	0.5066598547445591	[315]	[223,146,287]	4	hSpCas9	negative selection	2221302
4645394	4645417	3	+	26627737	HCT116	viability after 18 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	-0.08426467990294717	[632]	[406,102,371]	0	hSpCas9	negative selection	2221303
4564125	4564148	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGACGGGGTTTCACCATGTAGG	ITPR1	ENSG00000150995	1.7100356304154607	[4,2]	[3,0]	6	dCas9-VP64	positive selection	2409737
4598527	4598550	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGGATTGCTTGAGCTCGGG	ITPR1	ENSG00000150995	-0.7307069701167457	[14,47]	[6,0]	-4	dCas9-VP64	positive selection	2424959
4673777	4673800	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCACCGTGTTAGCTAGGACGG	ITPR1	ENSG00000150995	-0.43622771658323056	[174,104]	[36,6]	-2	dCas9-VP64	positive selection	2433016
4512200	4512223	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTCAAGCCATCCTCCCACCTTGG	ITPR1	ENSG00000150995	-1.0550787617713646	[224,291]	[11,42]	-6	dCas9-VP64	positive selection	2436427
4627096	4627119	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCACCGTGCCGGG	ITPR1	ENSG00000150995	-0.779191386983709	[52,249]	[14,23]	-4	dCas9-VP64	positive selection	2445686
4513991	4514014	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGGAGAATCGCTTGAACCTGG	ITPR1	ENSG00000150995	-0.7872021050505377	[82,16]	[7,2]	-4	dCas9-VP64	positive selection	2464284
4564125	4564148	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGACGGGGTTTCACCATGTAGG	ITPR1	ENSG00000150995	-0.28524240662887035	[88,68]	[26,14]	-3	dCas9-VP64	positive selection	2504992
4598527	4598550	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGGATTGCTTGAGCTCGGG	ITPR1	ENSG00000150995	-0.11990712036238094	[57,84]	[32,8]	-1	dCas9-VP64	positive selection	2520214
4673777	4673800	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCACCGTGTTAGCTAGGACGG	ITPR1	ENSG00000150995	1.4735482921306557	[116,143]	[227,15]	8	dCas9-VP64	positive selection	2528271
4512200	4512223	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTCAAGCCATCCTCCCACCTTGG	ITPR1	ENSG00000150995	0.12096276410502044	[78,167]	[40,44]	1	dCas9-VP64	positive selection	2531682
4627096	4627119	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCACCGTGCCGGG	ITPR1	ENSG00000150995	0.389783500937638	[291,598]	[109,262]	3	dCas9-VP64	positive selection	2540941
4513991	4514014	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGGAGAATCGCTTGAACCTGG	ITPR1	ENSG00000150995	-0.42856361530074616	[34,35]	[8,6]	-4	dCas9-VP64	positive selection	2559539
4673280	4673303	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-0.5766158354000879	[2,3]	[2,0]	-7	hSpCas9	positive selection	2996264
4667479	4667502	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGGAAAAACACATTACCGCGG	ITPR1	ENSG00000150995	-0.37521650650931243	[3,3]	[1,1]	-5	hSpCas9	positive selection	2996265
4673330	4673353	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGGCGGGCATATTTCACGGGGG	ITPR1	ENSG00000150995	-0.3068851906949382	[3,3]	[3,1]	-4	hSpCas9	positive selection	2996266
4663149	4663172	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTCCAAGCCCAACAGAGAACGG	ITPR1	ENSG00000150995	-0.8769656663560719	[1,0]	[0,0]	-8	hSpCas9	positive selection	2996267
4673280	4673303	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-0.04412049541871069	[2,2]	[4,0]	0	hSpCas9	positive selection	3064122
4667479	4667502	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGGAAAAACACATTACCGCGG	ITPR1	ENSG00000150995	0.1650502931726232	[3,3]	[3,2]	3	hSpCas9	positive selection	3064123
4673330	4673353	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGGCGGGCATATTTCACGGGGG	ITPR1	ENSG00000150995	0.24800578189100697	[3,3]	[3,2]	4	hSpCas9	positive selection	3064124
4663149	4663172	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTCCAAGCCCAACAGAGAACGG	ITPR1	ENSG00000150995	-0.9219194548701046	[1,1]	[0,0]	-9	hSpCas9	positive selection	3064125
4627796	4627819		+	24336571	A375	resistance to PLX after 7 days	ACTCTGCCCAAAAGCAGTTCTGG	ITPR1	ENSG00000150995	0.005667934962238386	[46,56]	[53,48]	0	hSpCas9	positive selection	3121899
4521024	4521047		-	24336571	A375	resistance to PLX after 7 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	0.05585180391433142	[33,32]	[32,35]	2	hSpCas9	positive selection	3121900
4521052	4521075		-	24336571	A375	resistance to PLX after 7 days	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.126558828586963	[48,50]	[54,52]	4	hSpCas9	positive selection	3121901
4627796	4627819		+	24336571	A375	resistance to PLX after 14 days	ACTCTGCCCAAAAGCAGTTCTGG	ITPR1	ENSG00000150995	-0.7951711406326953	[43,61]	[13,13]	-8	hSpCas9	positive selection	3179692
4521024	4521047		-	24336571	A375	resistance to PLX after 14 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	0.7393571175941052	[38,31]	[27,26]	6	hSpCas9	positive selection	3179693
4521052	4521075		-	24336571	A375	resistance to PLX after 14 days	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.03465578619839427	[51,60]	[25,26]	0	hSpCas9	positive selection	3179694
4627796	4627819		+	24336571	A375	viability after 7 days	ACTCTGCCCAAAAGCAGTTCTGG	ITPR1	ENSG00000150995	0.5624532886644482	[36]	[46,56]	8	hSpCas9	negative selection	3237485
4521024	4521047		-	24336571	A375	viability after 7 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.7655403239268108	[59]	[33,32]	-8	hSpCas9	negative selection	3237486
4521052	4521075		-	24336571	A375	viability after 7 days	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.6857371596716482	[32]	[48,50]	8	hSpCas9	negative selection	3237487
4627796	4627819		+	24336571	A375	viability after 14 days	ACTCTGCCCAAAAGCAGTTCTGG	ITPR1	ENSG00000150995	0.6110590656494759	[36]	[43,61]	7	hSpCas9	negative selection	3295278
4521024	4521047		-	24336571	A375	viability after 14 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.659152188092913	[59]	[38,31]	-7	hSpCas9	negative selection	3295279
4521052	4521075		-	24336571	A375	viability after 14 days	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.8676458046637614	[32]	[51,60]	9	hSpCas9	negative selection	3295280
4627767	4627790	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	-0.2583736268382073	[182,182]	[0,0]	-1	hSpCas9	positive selection	3374862
4521052	4521075	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.36250844813789157	[118,118]	[0,0]	2	hSpCas9	positive selection	3374863
4521040	4521063	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.7199537120540815	[251,251]	[0,0]	-5	hSpCas9	positive selection	3374864
4673280	4673303	3	-	26780180	HT29	viability (Avana library 4 designs)	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	1.73778428044501	[]	[]	6	hSpCas9	negative selection	3433662
4667478	4667501	3	+	26780180	HT29	viability (Avana library 4 designs)	CCTGGAAAAACACATTACCGCGG	ITPR1	ENSG00000150995	0.514532839188721	[]	[]	2	hSpCas9	negative selection	3433663
4673330	4673353	3	-	26780180	HT29	viability (Avana library 4 designs)	GAGGCGGGCATATTTCACGGGGG	ITPR1	ENSG00000150995	0.946420818294747	[]	[]	3	hSpCas9	negative selection	3433664
4663148	4663171	3	+	26780180	HT29	viability (Avana library 4 designs)	TCTCCAAGCCCAACAGAGAACGG	ITPR1	ENSG00000150995	0.41586606986333	[]	[]	1	hSpCas9	negative selection	3433665
4667478	4667501	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGAAAAACACATTACCGCGG	ITPR1	ENSG00000150995	1.12693213668435	[]	[]	1	hSpCas9	negative selection	3520380
4663148	4663171	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCCAAGCCCAACAGAGAACGG	ITPR1	ENSG00000150995	-1.43123767010396	[]	[]	-2	hSpCas9	negative selection	3520381
4673280	4673303	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-3.37752148387996	[]	[]	-4	hSpCas9	negative selection	3520382
4673330	4673353	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGGCGGGCATATTTCACGGGGG	ITPR1	ENSG00000150995	1.11918573104748	[]	[]	1	hSpCas9	negative selection	3520383
4691131	4691154	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTCTTGTGCCAGATCCTGGAGG	ITPR1	ENSG00000150995	6.72367406638996	[]	[]	9	hSpCas9	negative selection	3520384
4673229	4673252	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTCTCGTCAGACATGCAGCGG	ITPR1	ENSG00000150995	-2.12665069523453	[]	[]	-3	hSpCas9	negative selection	3520385
4667478	4667501	3	+	26780180	A375	viability (Avana lentiGuide)	CCTGGAAAAACACATTACCGCGG	ITPR1	ENSG00000150995	5.0935384988742	[]	[]	4	hSpCas9	negative selection	3629039
4663148	4663171	3	+	26780180	A375	viability (Avana lentiGuide)	TCTCCAAGCCCAACAGAGAACGG	ITPR1	ENSG00000150995	-6.86452290154595	[]	[]	-9	hSpCas9	negative selection	3629040
4673280	4673303	3	-	26780180	A375	viability (Avana lentiGuide)	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	9.46323001281424	[]	[]	6	hSpCas9	negative selection	3629041
4673330	4673353	3	-	26780180	A375	viability (Avana lentiGuide)	GAGGCGGGCATATTTCACGGGGG	ITPR1	ENSG00000150995	4.06607910338896	[]	[]	4	hSpCas9	negative selection	3629042
4691131	4691154	3	+	26780180	A375	viability (Avana lentiGuide)	ACTCTTGTGCCAGATCCTGGAGG	ITPR1	ENSG00000150995	-4.64842498416884	[]	[]	-7	hSpCas9	negative selection	3629043
4673229	4673252	3	-	26780180	A375	viability (Avana lentiGuide)	GGTTCTCGTCAGACATGCAGCGG	ITPR1	ENSG00000150995	0.895935664012506	[]	[]	1	hSpCas9	negative selection	3629044
4667478	4667501	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGAAAAACACATTACCGCGG	ITPR1	ENSG00000150995	-0.3970367207626918	[4]	[4,2]	-5	hSpCas9	positive selection	3737698
4663148	4663171	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCCAAGCCCAACAGAGAACGG	ITPR1	ENSG00000150995	-0.40569973331339204	[0]	[0,0]	-6	hSpCas9	positive selection	3737699
4673280	4673303	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-0.7592737102749916	[3]	[2,1]	-8	hSpCas9	positive selection	3737700
4673330	4673353	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGGCGGGCATATTTCACGGGGG	ITPR1	ENSG00000150995	-0.11696341893548377	[4]	[4,3]	-2	hSpCas9	positive selection	3737701
4691131	4691154	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTCTTGTGCCAGATCCTGGAGG	ITPR1	ENSG00000150995	0.22792798271135295	[5]	[6,6]	6	hSpCas9	positive selection	3737702
4673229	4673252	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTCTCGTCAGACATGCAGCGG	ITPR1	ENSG00000150995	-0.8484322235361215	[4]	[2,1]	-8	hSpCas9	positive selection	3737703
4667478	4667501	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGAAAAACACATTACCGCGG	ITPR1	ENSG00000150995	0.14066267912779712	[5]	[5,3]	3	hSpCas9	positive selection	3846305
4663148	4663171	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCCAAGCCCAACAGAGAACGG	ITPR1	ENSG00000150995	-0.143365844298176	[1]	[1,1]	-2	hSpCas9	positive selection	3846306
4673280	4673303	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-0.5400441646500164	[4]	[1,2]	-6	hSpCas9	positive selection	3846307
4673330	4673353	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGGCGGGCATATTTCACGGGGG	ITPR1	ENSG00000150995	-0.00881526066145387	[5]	[4,5]	0	hSpCas9	positive selection	3846308
4691131	4691154	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTCTTGTGCCAGATCCTGGAGG	ITPR1	ENSG00000150995	0.2529167465468973	[4]	[5,4]	6	hSpCas9	positive selection	3846309
4673229	4673252	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTCTCGTCAGACATGCAGCGG	ITPR1	ENSG00000150995	0.06202564102451054	[5]	[4,4]	1	hSpCas9	positive selection	3846310
4639449	4639472	3	-	26780180	A375	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	-0.10244035811575	[]	[]	-3	hSpCas9	negative selection	3952334
4639435	4639458	3	+	26780180	A375	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.630913829597569	[]	[]	2	hSpCas9	negative selection	3952335
4627847	4627870	3	-	26780180	A375	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	1.04487541067515	[]	[]	5	hSpCas9	negative selection	3952336
4627767	4627790	3	-	26780180	A375	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.472481953515958	[]	[]	1	hSpCas9	negative selection	3952337
4521040	4521063	3	+	26780180	A375	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	1.52276306806264	[]	[]	8	hSpCas9	negative selection	3952338
4521052	4521075	3	-	26780180	A375	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	1.08609498709495	[]	[]	5	hSpCas9	negative selection	3952339
4639449	4639472	3	-	26780180	HT29	viability (GeCKOv2 library)	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.47310667911856	[]	[]	1	hSpCas9	negative selection	4060300
4639435	4639458	3	+	26780180	HT29	viability (GeCKOv2 library)	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.968428373386992	[]	[]	4	hSpCas9	negative selection	4060301
4627847	4627870	3	-	26780180	HT29	viability (GeCKOv2 library)	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	1.11972261236586	[]	[]	5	hSpCas9	negative selection	4060302
4627767	4627790	3	-	26780180	HT29	viability (GeCKOv2 library)	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.961427728710924	[]	[]	4	hSpCas9	negative selection	4060303
4521040	4521063	3	+	26780180	HT29	viability (GeCKOv2 library)	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	1.62073738479241	[]	[]	8	hSpCas9	negative selection	4060304
4521052	4521075	3	-	26780180	HT29	viability (GeCKOv2 library)	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	1.27757329349531	[]	[]	6	hSpCas9	negative selection	4060305
4627796	4627819	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTCTGCCCAAAAGCAGTTCTGG	ITPR1	ENSG00000150995	-0.014027345677699365	[5]	[3,3]	0	hSpCas9	positive selection	4145623
4521024	4521047	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	0.2192264855402557	[5]	[3,4]	5	hSpCas9	positive selection	4145624
4521052	4521075	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.27730129072330634	[5]	[4,4]	7	hSpCas9	positive selection	4145625
4627796	4627819	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTCTGCCCAAAAGCAGTTCTGG	ITPR1	ENSG00000150995	0.8603843131059499	[5]	[3,4,1,4]	5	hSpCas9	positive selection	4209645
4521024	4521047	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	1.0749574080056656	[5]	[5,5,6,4]	7	hSpCas9	positive selection	4209646
4521052	4521075	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	1.0187099835248867	[4]	[5,4,5,2]	7	hSpCas9	positive selection	4209647
4627847	4627870	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.19222443666089314	[2]	[2,2]	4	hSpCas9	positive selection	4277532
4639435	4639458	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.5793968703084477	[1]	[1,2]	9	hSpCas9	positive selection	4277533
4639449	4639472	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.6645337957788744	[4]	[4,6]	9	hSpCas9	positive selection	4277534
4627767	4627790	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.2995696114257045	[3]	[3,2]	6	hSpCas9	positive selection	4341787
4521052	4521075	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	-0.14902957140116804	[2]	[1,1]	-3	hSpCas9	positive selection	4341788
4521040	4521063	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.16865042732160118	[3]	[3,1]	-3	hSpCas9	positive selection	4341789
4673365	4673387	3	-	27760321	OCIAML3	viability	CGTCAATGGCGATCTCCGAGGG	ITPR1	ENSG00000150995	0.09985571495021772	[863,682]	[605,693]	1	hSpCas9	negative selection	4410686
4683449	4683471	3	-	27760321	OCIAML3	viability	GTAGTCATGCATCGTCAAGTGG	ITPR1	ENSG00000150995	-0.04638920185528028	[881,778]	[494,800]	0	hSpCas9	negative selection	4410687
4683744	4683766	3	-	27760321	OCIAML3	viability	ACCATCCATAGTCTCATCGGGG	ITPR1	ENSG00000150995	0.26116385948114784	[600,535]	[400,702]	3	hSpCas9	negative selection	4410688
4685153	4685175	3	+	27760321	OCIAML3	viability	AACATGGGCGCGCACGCCGTGG	ITPR1	ENSG00000150995	0.02248031331539138	[558,447]	[401,391]	0	hSpCas9	negative selection	4410689
4693513	4693535	3	-	27760321	OCIAML3	viability	TCTGTCGTTGTAGAACACGAGG	ITPR1	ENSG00000150995	0.17470820153527425	[367,374]	[340,313]	2	hSpCas9	negative selection	4410690
4673365	4673387	3	-	27760321	OCIAML2	viability	CGTCAATGGCGATCTCCGAGGG	ITPR1	ENSG00000150995	0.08907457524369211	[863,682]	[647,678]	1	hSpCas9	negative selection	4494149
4683449	4683471	3	-	27760321	OCIAML2	viability	GTAGTCATGCATCGTCAAGTGG	ITPR1	ENSG00000150995	0.13976542412483384	[881,778]	[614,901]	1	hSpCas9	negative selection	4494150
4683744	4683766	3	-	27760321	OCIAML2	viability	ACCATCCATAGTCTCATCGGGG	ITPR1	ENSG00000150995	0.3933625264251681	[600,535]	[594,613]	5	hSpCas9	negative selection	4494151
4685153	4685175	3	+	27760321	OCIAML2	viability	AACATGGGCGCGCACGCCGTGG	ITPR1	ENSG00000150995	-0.07842210710786873	[558,447]	[304,486]	-1	hSpCas9	negative selection	4494152
4693513	4693535	3	-	27760321	OCIAML2	viability	TCTGTCGTTGTAGAACACGAGG	ITPR1	ENSG00000150995	0.02186380389117884	[367,374]	[191,456]	0	hSpCas9	negative selection	4494153
4673365	4673387	3	-	27760321	MV411	viability	CGTCAATGGCGATCTCCGAGGG	ITPR1	ENSG00000150995	0.623117514033004	[863,682]	[781,779]	4	hSpCas9	negative selection	4577612
4683449	4683471	3	-	27760321	MV411	viability	GTAGTCATGCATCGTCAAGTGG	ITPR1	ENSG00000150995	-0.6953002343143118	[881,778]	[159,604]	-5	hSpCas9	negative selection	4577613
4683744	4683766	3	-	27760321	MV411	viability	ACCATCCATAGTCTCATCGGGG	ITPR1	ENSG00000150995	-0.08198251016175706	[600,535]	[269,479]	0	hSpCas9	negative selection	4577614
4685153	4685175	3	+	27760321	MV411	viability	AACATGGGCGCGCACGCCGTGG	ITPR1	ENSG00000150995	0.27556034701881005	[558,447]	[243,633]	2	hSpCas9	negative selection	4577615
4693513	4693535	3	-	27760321	MV411	viability	TCTGTCGTTGTAGAACACGAGG	ITPR1	ENSG00000150995	0.9069893218309191	[367,374]	[652,173]	6	hSpCas9	negative selection	4577616
4673365	4673387	3	-	27760321	HL60	viability	CGTCAATGGCGATCTCCGAGGG	ITPR1	ENSG00000150995	0.4437902478071506	[863,682]	[853,853]	5	hSpCas9	negative selection	4661075
4683449	4683471	3	-	27760321	HL60	viability	GTAGTCATGCATCGTCAAGTGG	ITPR1	ENSG00000150995	-0.012810011720103764	[881,778]	[677,663]	0	hSpCas9	negative selection	4661076
4683744	4683766	3	-	27760321	HL60	viability	ACCATCCATAGTCTCATCGGGG	ITPR1	ENSG00000150995	-0.08661064852170247	[600,535]	[559,305]	-1	hSpCas9	negative selection	4661077
4685153	4685175	3	+	27760321	HL60	viability	AACATGGGCGCGCACGCCGTGG	ITPR1	ENSG00000150995	0.5056868202233866	[558,447]	[649,506]	6	hSpCas9	negative selection	4661078
4693513	4693535	3	-	27760321	HL60	viability	TCTGTCGTTGTAGAACACGAGG	ITPR1	ENSG00000150995	0.07233543877943402	[367,374]	[315,324]	0	hSpCas9	negative selection	4661079
4673365	4673387	3	-	27760321	HT1080	viability	CGTCAATGGCGATCTCCGAGGG	ITPR1	ENSG00000150995	0.40342852423256337	[682,532]	[232,415]	2	hSpCas9	negative selection	4744538
4683449	4683471	3	-	27760321	HT1080	viability	GTAGTCATGCATCGTCAAGTGG	ITPR1	ENSG00000150995	0.631129810441266	[778,607]	[456,395]	3	hSpCas9	negative selection	4744539
4683744	4683766	3	-	27760321	HT1080	viability	ACCATCCATAGTCTCATCGGGG	ITPR1	ENSG00000150995	0.6041322738372652	[535,417]	[337,234]	3	hSpCas9	negative selection	4744540
4685153	4685175	3	+	27760321	HT1080	viability	AACATGGGCGCGCACGCCGTGG	ITPR1	ENSG00000150995	0.6697602980327284	[447,349]	[186,324]	3	hSpCas9	negative selection	4744541
4693513	4693535	3	-	27760321	HT1080	viability	TCTGTCGTTGTAGAACACGAGG	ITPR1	ENSG00000150995	-0.10568737647815334	[374,292]	[84,165]	0	hSpCas9	negative selection	4744542
4673365	4673387	3	-	27760321	HT29	viability after 7 days	CGTCAATGGCGATCTCCGAGGG	ITPR1	ENSG00000150995	0.05410993707108991	[682,532]	[730,1003,690]	0	hSpCas9	negative selection	4828001
4683449	4683471	3	-	27760321	HT29	viability after 7 days	GTAGTCATGCATCGTCAAGTGG	ITPR1	ENSG00000150995	0.3287397192583018	[778,607]	[1337,1249,810]	5	hSpCas9	negative selection	4828002
4683744	4683766	3	-	27760321	HT29	viability after 7 days	ACCATCCATAGTCTCATCGGGG	ITPR1	ENSG00000150995	0.4635444399751468	[535,417]	[978,739,835]	7	hSpCas9	negative selection	4828003
4685153	4685175	3	+	27760321	HT29	viability after 7 days	AACATGGGCGCGCACGCCGTGG	ITPR1	ENSG00000150995	0.04030807176132059	[447,349]	[534,456,588]	0	hSpCas9	negative selection	4828004
4693513	4693535	3	-	27760321	HT29	viability after 7 days	TCTGTCGTTGTAGAACACGAGG	ITPR1	ENSG00000150995	-0.9284282459138665	[374,292]	[172,234,259]	-8	hSpCas9	negative selection	4828005
4673365	4673387	3	-	27760321	HT29	viability after 25 days	CGTCAATGGCGATCTCCGAGGG	ITPR1	ENSG00000150995	0.21235534249342958	[682,532]	[624,763,1062]	2	hSpCas9	negative selection	4911464
4683449	4683471	3	-	27760321	HT29	viability after 25 days	GTAGTCATGCATCGTCAAGTGG	ITPR1	ENSG00000150995	0.09220993751535722	[778,607]	[790,699,1068]	0	hSpCas9	negative selection	4911465
4683744	4683766	3	-	27760321	HT29	viability after 25 days	ACCATCCATAGTCTCATCGGGG	ITPR1	ENSG00000150995	0.6283281434690846	[535,417]	[763,816,962]	7	hSpCas9	negative selection	4911466
4685153	4685175	3	+	27760321	HT29	viability after 25 days	AACATGGGCGCGCACGCCGTGG	ITPR1	ENSG00000150995	0.4004766886279969	[447,349]	[603,690,498]	4	hSpCas9	negative selection	4911467
4693513	4693535	3	-	27760321	HT29	viability after 25 days	TCTGTCGTTGTAGAACACGAGG	ITPR1	ENSG00000150995	-0.17445719305753543	[374,292]	[259,430,326]	-2	hSpCas9	negative selection	4911468
4673365	4673387	3	-	27760321	HT29	viability after 22 days	CGTCAATGGCGATCTCCGAGGG	ITPR1	ENSG00000150995	0.387261783688568	[682,532]	[970,912,871]	4	hSpCas9	negative selection	4994927
4683449	4683471	3	-	27760321	HT29	viability after 22 days	GTAGTCATGCATCGTCAAGTGG	ITPR1	ENSG00000150995	0.27888379496881843	[778,607]	[936,1009,971]	3	hSpCas9	negative selection	4994928
4683744	4683766	3	-	27760321	HT29	viability after 22 days	ACCATCCATAGTCTCATCGGGG	ITPR1	ENSG00000150995	0.9382270354343467	[535,417]	[1182,855,1127]	9	hSpCas9	negative selection	4994929
4685153	4685175	3	+	27760321	HT29	viability after 22 days	AACATGGGCGCGCACGCCGTGG	ITPR1	ENSG00000150995	0.6131444796037043	[447,349]	[578,642,899]	6	hSpCas9	negative selection	4994930
4693513	4693535	3	-	27760321	HT29	viability after 22 days	TCTGTCGTTGTAGAACACGAGG	ITPR1	ENSG00000150995	0.02045986438018446	[374,292]	[466,411,292]	0	hSpCas9	negative selection	4994931
4673365	4673387	3	-	27760321	HT29	viability after 19 days	CGTCAATGGCGATCTCCGAGGG	ITPR1	ENSG00000150995	-0.026373587750081806	[682,532]	[801,701,560]	0	hSpCas9	negative selection	5078390
4683449	4683471	3	-	27760321	HT29	viability after 19 days	GTAGTCATGCATCGTCAAGTGG	ITPR1	ENSG00000150995	0.4510327114352507	[778,607]	[1242,710,1305]	4	hSpCas9	negative selection	5078391
4683744	4683766	3	-	27760321	HT29	viability after 19 days	ACCATCCATAGTCTCATCGGGG	ITPR1	ENSG00000150995	0.7991895015199357	[535,417]	[787,952,1083]	7	hSpCas9	negative selection	5078392
4685153	4685175	3	+	27760321	HT29	viability after 19 days	AACATGGGCGCGCACGCCGTGG	ITPR1	ENSG00000150995	-0.0012602325220017752	[447,349]	[577,390,412]	0	hSpCas9	negative selection	5078393
4693513	4693535	3	-	27760321	HT29	viability after 19 days	TCTGTCGTTGTAGAACACGAGG	ITPR1	ENSG00000150995	-0.04858635712978397	[374,292]	[668,282,193]	0	hSpCas9	negative selection	5078394
4673365	4673387	3	-	27760321	HT29	viability after 16 days	CGTCAATGGCGATCTCCGAGGG	ITPR1	ENSG00000150995	0.44298625404779746	[682,532]	[960,710,1110]	5	hSpCas9	negative selection	5161853
4683449	4683471	3	-	27760321	HT29	viability after 16 days	GTAGTCATGCATCGTCAAGTGG	ITPR1	ENSG00000150995	0.33790646842927574	[778,607]	[975,1110,850]	4	hSpCas9	negative selection	5161854
4683744	4683766	3	-	27760321	HT29	viability after 16 days	ACCATCCATAGTCTCATCGGGG	ITPR1	ENSG00000150995	0.30452342323603554	[535,417]	[662,713,598]	3	hSpCas9	negative selection	5161855
4685153	4685175	3	+	27760321	HT29	viability after 16 days	AACATGGGCGCGCACGCCGTGG	ITPR1	ENSG00000150995	0.040411991273316045	[447,349]	[411,451,508]	0	hSpCas9	negative selection	5161856
4693513	4693535	3	-	27760321	HT29	viability after 16 days	TCTGTCGTTGTAGAACACGAGG	ITPR1	ENSG00000150995	0.19096657648051635	[374,292]	[361,411,499]	2	hSpCas9	negative selection	5161857
4673365	4673387	3	-	27760321	HT29	viability after 13 days	CGTCAATGGCGATCTCCGAGGG	ITPR1	ENSG00000150995	0.3882816565689936	[682,532]	[936,954,879]	5	hSpCas9	negative selection	5245316
4683449	4683471	3	-	27760321	HT29	viability after 13 days	GTAGTCATGCATCGTCAAGTGG	ITPR1	ENSG00000150995	0.2833779133103492	[778,607]	[958,1095,887]	3	hSpCas9	negative selection	5245317
4683744	4683766	3	-	27760321	HT29	viability after 13 days	ACCATCCATAGTCTCATCGGGG	ITPR1	ENSG00000150995	0.6439565818342434	[535,417]	[802,926,863]	8	hSpCas9	negative selection	5245318
4685153	4685175	3	+	27760321	HT29	viability after 13 days	AACATGGGCGCGCACGCCGTGG	ITPR1	ENSG00000150995	0.2431032096918854	[447,349]	[519,616,508]	3	hSpCas9	negative selection	5245319
4693513	4693535	3	-	27760321	HT29	viability after 13 days	TCTGTCGTTGTAGAACACGAGG	ITPR1	ENSG00000150995	-0.5742248361846373	[374,292]	[165,235,371]	-6	hSpCas9	negative selection	5245320
4673365	4673387	3	-	27760321	HT29	viability after 10 days	CGTCAATGGCGATCTCCGAGGG	ITPR1	ENSG00000150995	-0.011149127677170578	[682,532]	[736,906,622]	0	hSpCas9	negative selection	5328779
4683449	4683471	3	-	27760321	HT29	viability after 10 days	GTAGTCATGCATCGTCAAGTGG	ITPR1	ENSG00000150995	0.4711325522693922	[778,607]	[837,1389,1373]	6	hSpCas9	negative selection	5328780
4683744	4683766	3	-	27760321	HT29	viability after 10 days	ACCATCCATAGTCTCATCGGGG	ITPR1	ENSG00000150995	0.2690821856304966	[535,417]	[611,828,714]	3	hSpCas9	negative selection	5328781
4685153	4685175	3	+	27760321	HT29	viability after 10 days	AACATGGGCGCGCACGCCGTGG	ITPR1	ENSG00000150995	0.21035138935696582	[447,349]	[884,535,312]	2	hSpCas9	negative selection	5328782
4693513	4693535	3	-	27760321	HT29	viability after 10 days	TCTGTCGTTGTAGAACACGAGG	ITPR1	ENSG00000150995	-0.44972240616299947	[374,292]	[383,309,223]	-5	hSpCas9	negative selection	5328783
4673365	4673387	3	-	27760321	MOLM13	viability	CGTCAATGGCGATCTCCGAGGG	ITPR1	ENSG00000150995	0.740498830725593	[863,682]	[266,1113]	5	hSpCas9	negative selection	5412242
4683449	4683471	3	-	27760321	MOLM13	viability	GTAGTCATGCATCGTCAAGTGG	ITPR1	ENSG00000150995	0.5914565298335395	[881,778]	[835,592]	4	hSpCas9	negative selection	5412243
4683744	4683766	3	-	27760321	MOLM13	viability	ACCATCCATAGTCTCATCGGGG	ITPR1	ENSG00000150995	1.232100207810631	[600,535]	[1237,338]	8	hSpCas9	negative selection	5412244
4685153	4685175	3	+	27760321	MOLM13	viability	AACATGGGCGCGCACGCCGTGG	ITPR1	ENSG00000150995	0.17829861233619224	[558,447]	[156,457]	1	hSpCas9	negative selection	5412245
4693513	4693535	3	-	27760321	MOLM13	viability	TCTGTCGTTGTAGAACACGAGG	ITPR1	ENSG00000150995	0.9372609759847301	[367,374]	[382,419]	6	hSpCas9	negative selection	5412246
4493376	4493399	3	+	27661255	K562	viability	GCGTTTCCTCAAGCTCGCTGGGG	ITPR1	ENSG00000150995	-0.0046109193444165975	[186,129]	[146,109]	0	dCas9-KRAB	negative selection	5487499
4493462	4493485	3	+	27661255	K562	viability	GCGCACGCCGAGAGGAGGTGTGG	ITPR1	ENSG00000150995	0.4574941536182644	[47,60]	[92,30]	9	dCas9-KRAB	negative selection	5487500
4493524	4493547	3	+	27661255	K562	viability	GCGGACATGGGATTACCCAGCGG	ITPR1	ENSG00000150995	0.27220526077503515	[349,440]	[400,361]	8	dCas9-KRAB	negative selection	5487501
4493496	4493519	3	-	27661255	K562	viability	GGGAGCTCGTTCCGTTAGGATGG	ITPR1	ENSG00000150995	-0.12845898768076564	[871,855]	[758,522]	-4	dCas9-KRAB	negative selection	5487502
4627847	4627870	3	-	27260156	BXPC3	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.08165845226756119	[453]	[555,514,404,523]	1	hSpCas9	negative selection	5549992
4639435	4639458	3	+	27260156	BXPC3	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.055628828552102494	[159]	[117,219,132,173]	-1	hSpCas9	negative selection	5549993
4639449	4639472	3	-	27260156	BXPC3	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.3798407667165753	[1357]	[1765,1746,1822,2084]	7	hSpCas9	negative selection	5549994
4627767	4627790	3	-	27260156	BXPC3	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	-0.014667052139360509	[537]	[487,586,513,650]	0	hSpCas9	negative selection	5614247
4521052	4521075	3	-	27260156	BXPC3	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.2522424689102068	[289]	[325,336,394,393]	5	hSpCas9	negative selection	5614248
4521040	4521063	3	+	27260156	BXPC3	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.17498895597261976	[770]	[677,670,796,712]	-4	hSpCas9	negative selection	5614249
4627847	4627870	3	-	27260156	A673	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	-0.022734359131058653	[453]	[499,486,525,634]	0	hSpCas9	negative selection	5671243
4639435	4639458	3	+	27260156	A673	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.0064293250746216835	[159]	[184,156,208,214]	0	hSpCas9	negative selection	5671244
4639449	4639472	3	-	27260156	A673	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.48110665325472235	[1357]	[2475,2114,2301,2230]	9	hSpCas9	negative selection	5671245
4627767	4627790	3	-	27260156	A673	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.07479384839828063	[537]	[749,625,623,732]	1	hSpCas9	negative selection	5735498
4521052	4521075	3	-	27260156	A673	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.335876465185587	[289]	[498,334,524,404]	7	hSpCas9	negative selection	5735499
4521040	4521063	3	+	27260156	A673	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.06509989103409786	[770]	[891,824,788,1043]	-2	hSpCas9	negative selection	5735500
4627847	4627870	3	-	27260156	A375	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.16386653483272012	[453]	[658,845,546,382]	2	hSpCas9	negative selection	5792494
4639435	4639458	3	+	27260156	A375	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.36101911725247837	[159]	[133,460,291,116]	5	hSpCas9	negative selection	5792495
4639449	4639472	3	-	27260156	A375	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.5953614297606453	[1357]	[2216,2731,2399,2285]	8	hSpCas9	negative selection	5792496
4627767	4627790	3	-	27260156	A375	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.18714272648260455	[537]	[670,879,758,586]	2	hSpCas9	negative selection	5856749
4521052	4521075	3	-	27260156	A375	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.2647710357121041	[289]	[251,433,444,487]	4	hSpCas9	negative selection	5856750
4521040	4521063	3	+	27260156	A375	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.19109785730844675	[770]	[838,859,901,585]	-3	hSpCas9	negative selection	5856751
4627847	4627870	3	-	27260156	COLO741	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	-0.1602406756330804	[453]	[587,484,490]	-3	hSpCas9	negative selection	5913745
4639435	4639458	3	+	27260156	COLO741	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.27950562086457187	[159]	[403,149,205]	6	hSpCas9	negative selection	5913746
4639449	4639472	3	-	27260156	COLO741	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.3607558241693132	[1357]	[2631,2442,1679]	7	hSpCas9	negative selection	5913747
4627767	4627790	3	-	27260156	COLO741	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	-0.1615789502523795	[537]	[656,659,534]	-3	hSpCas9	negative selection	5978000
4521052	4521075	3	-	27260156	COLO741	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.12667974772933355	[289]	[588,401,248]	2	hSpCas9	negative selection	5978001
4521040	4521063	3	+	27260156	COLO741	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.2700175395592123	[770]	[772,779,886]	-5	hSpCas9	negative selection	5978002
4627847	4627870	3	-	27260156	CAL120	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	-0.38586653926597647	[453]	[572,307,436]	-5	hSpCas9	negative selection	6034996
4639435	4639458	3	+	27260156	CAL120	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.3734660307073032	[159]	[380,309,103]	5	hSpCas9	negative selection	6034997
4639449	4639472	3	-	27260156	CAL120	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.5865399986786044	[1357]	[3215,2083,2415]	8	hSpCas9	negative selection	6034998
4627767	4627790	3	-	27260156	CAL120	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	-0.14146267075909547	[537]	[735,607,497]	-2	hSpCas9	negative selection	6099251
4521052	4521075	3	-	27260156	CAL120	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.30959052990210567	[289]	[369,571,388]	4	hSpCas9	negative selection	6099252
4521040	4521063	3	+	27260156	CAL120	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.06807782756939407	[770]	[1015,1086,661]	-1	hSpCas9	negative selection	6099253
4627847	4627870	3	-	27260156	CADOES1	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.26814921818137477	[453]	[500,610,597,316]	4	hSpCas9	negative selection	6156247
4639435	4639458	3	+	27260156	CADOES1	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.04888583886355491	[159]	[129,156,181,104]	-1	hSpCas9	negative selection	6156248
4639449	4639472	3	-	27260156	CADOES1	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.40685721323224056	[1357]	[1633,1641,1620,1805]	6	hSpCas9	negative selection	6156249
4627767	4627790	3	-	27260156	CADOES1	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.061986699016487845	[537]	[470,387,711,517]	1	hSpCas9	negative selection	6220502
4521052	4521075	3	-	27260156	CADOES1	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.43213134410095505	[289]	[320,278,377,481]	7	hSpCas9	negative selection	6220503
4521040	4521063	3	+	27260156	CADOES1	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.07232736758269065	[770]	[635,615,793,681]	-1	hSpCas9	negative selection	6220504
4627847	4627870	3	-	27260156	EWS502	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	-0.02994786052119721	[453]	[485,430,417,551]	0	hSpCas9	negative selection	6277498
4639435	4639458	3	+	27260156	EWS502	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.4419575966434086	[159]	[199,192,192,346]	7	hSpCas9	negative selection	6277499
4639449	4639472	3	-	27260156	EWS502	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.3682207978707912	[1357]	[1670,1928,1701,2155]	6	hSpCas9	negative selection	6277500
4627767	4627790	3	-	27260156	EWS502	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.28448012345640117	[537]	[749,538,732,755]	5	hSpCas9	negative selection	6341753
4521052	4521075	3	-	27260156	EWS502	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.2659930203348593	[289]	[408,304,407,350]	4	hSpCas9	negative selection	6341754
4521040	4521063	3	+	27260156	EWS502	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	0.15184051171465318	[770]	[848,1070,754,951]	2	hSpCas9	negative selection	6341755
4627847	4627870	3	-	27260156	EW8	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	-0.05500318856029784	[453]	[376,388,272,392]	-1	hSpCas9	negative selection	6398749
4639435	4639458	3	+	27260156	EW8	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.4058350271386757	[159]	[226,82,226,145]	7	hSpCas9	negative selection	6398750
4639449	4639472	3	-	27260156	EW8	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.6190560645171832	[1357]	[2039,1699,1478,1611]	9	hSpCas9	negative selection	6398751
4627767	4627790	3	-	27260156	EW8	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.04705201992526459	[537]	[554,334,392,537]	0	hSpCas9	negative selection	6463004
4521052	4521075	3	-	27260156	EW8	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.6370706625281741	[289]	[361,351,289,468]	9	hSpCas9	negative selection	6463005
4521040	4521063	3	+	27260156	EW8	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.06903355071207684	[770]	[830,554,517,515]	-1	hSpCas9	negative selection	6463006
4627847	4627870	3	-	27260156	CORL105	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	-0.006108050290883203	[453]	[516,453,594,561]	0	hSpCas9	negative selection	6520000
4639435	4639458	3	+	27260156	CORL105	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.165090186062818	[159]	[256,123,158,130]	-3	hSpCas9	negative selection	6520001
4639449	4639472	3	-	27260156	CORL105	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.5701654344582252	[1357]	[2644,2167,2719,1978]	9	hSpCas9	negative selection	6520002
4627767	4627790	3	-	27260156	CORL105	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.22125054248753584	[537]	[713,792,715,708]	4	hSpCas9	negative selection	6584255
4521052	4521075	3	-	27260156	CORL105	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.3741877042461948	[289]	[447,406,528,390]	7	hSpCas9	negative selection	6584256
4521040	4521063	3	+	27260156	CORL105	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	0.16520404886016526	[770]	[1057,804,961,1219]	3	hSpCas9	negative selection	6584257
4627847	4627870	3	-	27260156	HS294T	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.17195128621243488	[453]	[106,219,155,338]	2	hSpCas9	negative selection	6641251
4639435	4639458	3	+	27260156	HS294T	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.8322890029407899	[159]	[40,23,36,36]	-8	hSpCas9	negative selection	6641252
4639449	4639472	3	-	27260156	HS294T	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	1.1187360834176343	[1357]	[903,1016,869,1923]	9	hSpCas9	negative selection	6641253
4627767	4627790	3	-	27260156	HS294T	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.4841902518375656	[537]	[251,432,169,309]	6	hSpCas9	negative selection	6705506
4521052	4521075	3	-	27260156	HS294T	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.7556342011175785	[289]	[204,146,97,329]	8	hSpCas9	negative selection	6705507
4521040	4521063	3	+	27260156	HS294T	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	0.29758147249774225	[770]	[213,520,286,468]	4	hSpCas9	negative selection	6705508
4627847	4627870	3	-	27260156	HCC44	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	-0.014250117471933159	[453]	[468,423,664,506]	0	hSpCas9	negative selection	6762502
4639435	4639458	3	+	27260156	HCC44	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.02013447884572117	[159]	[223,142,204,173]	0	hSpCas9	negative selection	6762503
4639449	4639472	3	-	27260156	HCC44	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.5856002860994383	[1357]	[2734,1862,2406,2314]	8	hSpCas9	negative selection	6762504
4627767	4627790	3	-	27260156	HCC44	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.16952770234527775	[537]	[766,738,743,497]	2	hSpCas9	negative selection	6826757
4521052	4521075	3	-	27260156	HCC44	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.3767217900437362	[289]	[594,339,357,422]	6	hSpCas9	negative selection	6826758
4521040	4521063	3	+	27260156	HCC44	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.0758383949542718	[770]	[1041,695,974,658]	-1	hSpCas9	negative selection	6826759
4627847	4627870	3	-	27260156	G402	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.1541964114287864	[453]	[625,732,864,264]	2	hSpCas9	negative selection	6883753
4639435	4639458	3	+	27260156	G402	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.7025513570759647	[159]	[72,163,177,62]	-7	hSpCas9	negative selection	6883754
4639449	4639472	3	-	27260156	G402	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.7163491374576698	[1357]	[3477,2730,2223,2563]	8	hSpCas9	negative selection	6883755
4627767	4627790	3	-	27260156	G402	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.3638544446429166	[537]	[811,515,606,1389]	4	hSpCas9	negative selection	6948008
4521052	4521075	3	-	27260156	G402	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.29103874384009953	[289]	[657,181,452,453]	3	hSpCas9	negative selection	6948009
4521040	4521063	3	+	27260156	G402	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.07524490357141489	[770]	[1428,631,853,723]	-1	hSpCas9	negative selection	6948010
4627847	4627870	3	-	27260156	L33	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.09168194018406838	[453]	[451,222,321,427]	2	hSpCas9	negative selection	7005004
4639435	4639458	3	+	27260156	L33	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.452335748843846	[159]	[89,44,88,126]	-8	hSpCas9	negative selection	7005005
4639449	4639472	3	-	27260156	L33	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.5134203070087655	[1357]	[1823,840,1210,1952]	8	hSpCas9	negative selection	7005006
4627767	4627790	3	-	27260156	L33	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	-0.1500496425537592	[537]	[497,187,258,568]	-3	hSpCas9	negative selection	7069259
4521052	4521075	3	-	27260156	L33	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.03037676412341417	[289]	[323,100,219,263]	0	hSpCas9	negative selection	7069260
4521040	4521063	3	+	27260156	L33	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.24625700964391667	[770]	[871,225,363,591]	-5	hSpCas9	negative selection	7069261
4627847	4627870	3	-	27260156	K562	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.19291278348844523	[453]	[762,550,267,305]	2	hSpCas9	negative selection	7126255
4639435	4639458	3	+	27260156	K562	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.840750709563456	[159]	[116,222,519,154]	9	hSpCas9	negative selection	7126256
4639449	4639472	3	-	27260156	K562	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.5738873643927076	[1357]	[1615,1756,2009,1770]	7	hSpCas9	negative selection	7126257
4627767	4627790	3	-	27260156	K562	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	-0.3638152899530557	[537]	[400,562,338,210]	-4	hSpCas9	negative selection	7190510
4521052	4521075	3	-	27260156	K562	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.13008824304404687	[289]	[262,290,247,317]	1	hSpCas9	negative selection	7190511
4521040	4521063	3	+	27260156	K562	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.51865302273999	[770]	[440,415,443,587]	-6	hSpCas9	negative selection	7190512
4627847	4627870	3	-	27260156	HT29	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.009159196007664731	[453]	[673,638,357,561]	0	hSpCas9	negative selection	7247506
4639435	4639458	3	+	27260156	HT29	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.2866332115275476	[159]	[158,294,306,190]	5	hSpCas9	negative selection	7247507
4639449	4639472	3	-	27260156	HT29	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.4542765224255576	[1357]	[2365,2048,2421,2191]	8	hSpCas9	negative selection	7247508
4627767	4627790	3	-	27260156	HT29	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.30764100851238085	[537]	[1012,848,723,680]	6	hSpCas9	negative selection	7311761
4521052	4521075	3	-	27260156	HT29	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.12151903364298144	[289]	[262,481,442,346]	2	hSpCas9	negative selection	7311762
4521040	4521063	3	+	27260156	HT29	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.07325935134296091	[770]	[697,947,974,921]	-1	hSpCas9	negative selection	7311763
4627847	4627870	3	-	27260156	MHHES1	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.1803532931158048	[453]	[782,721,473,404]	3	hSpCas9	negative selection	7368757
4639435	4639458	3	+	27260156	MHHES1	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.21216374137587013	[159]	[341,220,167,133]	4	hSpCas9	negative selection	7368758
4639449	4639472	3	-	27260156	MHHES1	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.6446428056274591	[1357]	[2918,2876,2089,1859]	9	hSpCas9	negative selection	7368759
4627767	4627790	3	-	27260156	MHHES1	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.1349026786457167	[537]	[895,809,587,445]	2	hSpCas9	negative selection	7433012
4521052	4521075	3	-	27260156	MHHES1	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.30428269571767036	[289]	[416,427,441,336]	5	hSpCas9	negative selection	7433013
4521040	4521063	3	+	27260156	MHHES1	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.003332806980531733	[770]	[861,847,973,779]	0	hSpCas9	negative selection	7433014
4627847	4627870	3	-	27260156	MEWO	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.025467545103589343	[453]	[384,568,332]	0	hSpCas9	negative selection	7490008
4639435	4639458	3	+	27260156	MEWO	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.06056951783858766	[159]	[184,132,155]	1	hSpCas9	negative selection	7490009
4639449	4639472	3	-	27260156	MEWO	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.5828957907977235	[1357]	[1989,1792,1942]	9	hSpCas9	negative selection	7490010
4627767	4627790	3	-	27260156	MEWO	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.1435297281199504	[537]	[713,440,543]	3	hSpCas9	negative selection	7554263
4521052	4521075	3	-	27260156	MEWO	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.20744361805137268	[289]	[346,368,229]	4	hSpCas9	negative selection	7554264
4521040	4521063	3	+	27260156	MEWO	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.12397566682756833	[770]	[677,606,703]	-3	hSpCas9	negative selection	7554265
4627847	4627870	3	-	27260156	LNCAPCLONEFGC	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.18187783246958678	[453]	[488,450,497,432]	3	hSpCas9	negative selection	7611259
4639435	4639458	3	+	27260156	LNCAPCLONEFGC	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.2583935110362052	[159]	[81,165,131,103]	-4	hSpCas9	negative selection	7611260
4639449	4639472	3	-	27260156	LNCAPCLONEFGC	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.6213306905681675	[1357]	[1793,1864,2176,1777]	8	hSpCas9	negative selection	7611261
4627767	4627790	3	-	27260156	LNCAPCLONEFGC	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.2205511020453011	[537]	[561,539,776,424]	3	hSpCas9	negative selection	7675514
4521052	4521075	3	-	27260156	LNCAPCLONEFGC	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.4012941080040106	[289]	[319,260,287,515]	6	hSpCas9	negative selection	7675515
4521040	4521063	3	+	27260156	LNCAPCLONEFGC	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.21249841765207622	[770]	[604,451,753,631]	-3	hSpCas9	negative selection	7675516
4627847	4627870	3	-	27260156	PANC0327	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.2883349157158542	[453]	[421,508,509,520]	4	hSpCas9	negative selection	7732510
4639435	4639458	3	+	27260156	PANC0327	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.257739820337626	[159]	[203,118,160,204]	4	hSpCas9	negative selection	7732511
4639449	4639472	3	-	27260156	PANC0327	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.4679738428884843	[1357]	[1727,1712,1297,1932]	7	hSpCas9	negative selection	7732512
4627767	4627790	3	-	27260156	PANC0327	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.19234325082644943	[537]	[590,474,570,559]	3	hSpCas9	negative selection	7796765
4521052	4521075	3	-	27260156	PANC0327	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	-0.12538839847054462	[289]	[178,251,305,200]	-2	hSpCas9	negative selection	7796766
4521040	4521063	3	+	27260156	PANC0327	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.010408360954570206	[770]	[785,490,825,649]	0	hSpCas9	negative selection	7796767
4627847	4627870	3	-	27260156	NCIH2009	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.6637913431376539	[453]	[977,1096,930]	8	hSpCas9	negative selection	7853761
4639435	4639458	3	+	27260156	NCIH2009	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.17118435940099186	[159]	[199,332,209]	2	hSpCas9	negative selection	7853762
4639449	4639472	3	-	27260156	NCIH2009	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.647594659450025	[1357]	[3073,2746,3114]	8	hSpCas9	negative selection	7853763
4627767	4627790	3	-	27260156	NCIH2009	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.1894144068463101	[537]	[937,1017,626]	2	hSpCas9	negative selection	7918016
4521052	4521075	3	-	27260156	NCIH2009	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.12223100273432241	[289]	[439,498,381]	1	hSpCas9	negative selection	7918017
4521040	4521063	3	+	27260156	NCIH2009	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	0.018306127760509994	[770]	[1209,1011,1073]	0	hSpCas9	negative selection	7918018
4627847	4627870	3	-	27260156	NCIH1373	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.005451650589517222	[453]	[735,482,373,127]	0	hSpCas9	negative selection	7975012
4639435	4639458	3	+	27260156	NCIH1373	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.3967742947051456	[159]	[176,339,233,43]	4	hSpCas9	negative selection	7975013
4639449	4639472	3	-	27260156	NCIH1373	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	1.0024369096040835	[1357]	[3381,2392,2677,1027]	8	hSpCas9	negative selection	7975014
4627767	4627790	3	-	27260156	NCIH1373	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.22841918689139207	[537]	[476,822,270,326]	2	hSpCas9	negative selection	8039267
4521052	4521075	3	-	27260156	NCIH1373	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	1.2652940874281338	[289]	[1138,492,1054,130]	9	hSpCas9	negative selection	8039268
4521040	4521063	3	+	27260156	NCIH1373	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	0.03599623583731271	[770]	[727,691,1158,250]	0	hSpCas9	negative selection	8039269
4627847	4627870	3	-	27260156	PATU8902	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.013214254790922933	[453]	[572,697,346,1055]	0	hSpCas9	negative selection	8096263
4639435	4639458	3	+	27260156	PATU8902	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.14082498190377835	[159]	[339,116,76,521]	1	hSpCas9	negative selection	8096264
4639449	4639472	3	-	27260156	PATU8902	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.892764486767863	[1357]	[4433,4058,1826,4208]	8	hSpCas9	negative selection	8096265
4627767	4627790	3	-	27260156	PATU8902	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	-0.12107965955753702	[537]	[875,565,455,939]	-1	hSpCas9	negative selection	8160518
4521052	4521075	3	-	27260156	PATU8902	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.39612395340550327	[289]	[606,466,545,491]	4	hSpCas9	negative selection	8160519
4521040	4521063	3	+	27260156	PATU8902	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	0.09657976743825036	[770]	[1542,979,789,1385]	1	hSpCas9	negative selection	8160520
4627847	4627870	3	-	27260156	PANC1	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.048474175607358894	[453]	[500,590,339,237]	0	hSpCas9	negative selection	8217514
4639435	4639458	3	+	27260156	PANC1	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.008480231303527264	[159]	[172,147,164,70]	0	hSpCas9	negative selection	8217515
4639449	4639472	3	-	27260156	PANC1	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.5431528518246673	[1357]	[1282,2325,1572,1720]	8	hSpCas9	negative selection	8217516
4627767	4627790	3	-	27260156	PANC1	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.462629638471703	[537]	[645,802,766,395]	7	hSpCas9	negative selection	8281769
4521052	4521075	3	-	27260156	PANC1	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.16658855354181745	[289]	[135,327,452,220]	2	hSpCas9	negative selection	8281770
4521040	4521063	3	+	27260156	PANC1	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	0.10499077462547535	[770]	[634,876,628,727]	1	hSpCas9	negative selection	8281771
4627847	4627870	3	-	27260156	PANC0813	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.39600900121698596	[453]	[627,627,778,760]	6	hSpCas9	negative selection	8338765
4639435	4639458	3	+	27260156	PANC0813	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.36372317491362205	[159]	[250,90,181,73]	-5	hSpCas9	negative selection	8338766
4639449	4639472	3	-	27260156	PANC0813	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.6149064620958455	[1357]	[2550,2486,2520,2230]	8	hSpCas9	negative selection	8338767
4627767	4627790	3	-	27260156	PANC0813	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.12005993969702461	[537]	[660,790,600,689]	2	hSpCas9	negative selection	8403020
4521052	4521075	3	-	27260156	PANC0813	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.4440045944539951	[289]	[524,434,461,437]	7	hSpCas9	negative selection	8403021
4521040	4521063	3	+	27260156	PANC0813	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.09996174825592385	[770]	[883,839,827,830]	-2	hSpCas9	negative selection	8403022
4627847	4627870	3	-	27260156	RDES	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.24952907477098882	[453]	[439,449,763,918]	4	hSpCas9	negative selection	8460016
4639435	4639458	3	+	27260156	RDES	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.5068877126125657	[159]	[238,256,237,315]	7	hSpCas9	negative selection	8460017
4639449	4639472	3	-	27260156	RDES	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.6250341606300784	[1357]	[2212,2247,2626,2555]	8	hSpCas9	negative selection	8460018
4627767	4627790	3	-	27260156	RDES	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.0994050538470237	[537]	[476,614,717,906]	1	hSpCas9	negative selection	8524271
4521052	4521075	3	-	27260156	RDES	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.4563588120601988	[289]	[350,503,396,602]	7	hSpCas9	negative selection	8524272
4521040	4521063	3	+	27260156	RDES	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.0737415467979623	[770]	[744,814,743,1097]	-1	hSpCas9	negative selection	8524273
4627847	4627870	3	-	27260156	PC3	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.16577043819174123	[453]	[299,487,791,610]	3	hSpCas9	negative selection	8581267
4639435	4639458	3	+	27260156	PC3	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.24247567557663285	[159]	[54,161,327,91]	-5	hSpCas9	negative selection	8581268
4639449	4639472	3	-	27260156	PC3	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.28905910256779155	[1357]	[1078,1461,2885,1770]	6	hSpCas9	negative selection	8581269
4627767	4627790	3	-	27260156	PC3	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.17751677393930254	[537]	[367,641,652,834]	4	hSpCas9	negative selection	8645522
4521052	4521075	3	-	27260156	PC3	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.049535922764986084	[289]	[191,267,544,306]	1	hSpCas9	negative selection	8645523
4521040	4521063	3	+	27260156	PC3	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.23891965978045765	[770]	[429,751,864,664]	-5	hSpCas9	negative selection	8645524
4627847	4627870	3	-	27260156	PATU8988T	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.482235169964321	[453]	[605,439,712,679]	7	hSpCas9	negative selection	8702518
4639435	4639458	3	+	27260156	PATU8988T	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.19527270942306751	[159]	[287,147,107,160]	3	hSpCas9	negative selection	8702519
4639449	4639472	3	-	27260156	PATU8988T	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.4044271389902643	[1357]	[1918,1991,1470,1579]	7	hSpCas9	negative selection	8702520
4627767	4627790	3	-	27260156	PATU8988T	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.04140719205057172	[537]	[537,752,376,490]	0	hSpCas9	negative selection	8766773
4521052	4521075	3	-	27260156	PATU8988T	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.25402095458631163	[289]	[388,302,347,289]	4	hSpCas9	negative selection	8766774
4521040	4521063	3	+	27260156	PATU8988T	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.23206616289633847	[770]	[652,780,542,569]	-4	hSpCas9	negative selection	8766775
4627847	4627870	3	-	27260156	T47D	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	-0.12120054793076604	[453]	[492,502,439,508]	-3	hSpCas9	negative selection	8823769
4639435	4639458	3	+	27260156	T47D	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.008172839462399217	[159]	[171,224,140,200]	0	hSpCas9	negative selection	8823770
4639449	4639472	3	-	27260156	T47D	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.44938765056199603	[1357]	[2150,2050,2156,2294]	8	hSpCas9	negative selection	8823771
4627767	4627790	3	-	27260156	T47D	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.10781661930544845	[537]	[661,689,673,673]	2	hSpCas9	negative selection	8888024
4521052	4521075	3	-	27260156	T47D	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.058184245039750504	[289]	[338,369,310,386]	1	hSpCas9	negative selection	8888025
4521040	4521063	3	+	27260156	T47D	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.01620338468499405	[770]	[767,863,964,957]	0	hSpCas9	negative selection	8888026
4627847	4627870	3	-	27260156	SU8686	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.12422815525143044	[453]	[391,526,507,547]	2	hSpCas9	negative selection	8945020
4639435	4639458	3	+	27260156	SU8686	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.28044262791478203	[159]	[149,86,68,233]	-5	hSpCas9	negative selection	8945021
4639449	4639472	3	-	27260156	SU8686	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.6410610909471779	[1357]	[1730,1895,2191,2738]	9	hSpCas9	negative selection	8945022
4627767	4627790	3	-	27260156	SU8686	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.07603295656674336	[537]	[515,575,620,531]	1	hSpCas9	negative selection	9009275
4521052	4521075	3	-	27260156	SU8686	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.18377064589822345	[289]	[243,345,387,335]	3	hSpCas9	negative selection	9009276
4521040	4521063	3	+	27260156	SU8686	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.15664873460719209	[770]	[602,613,699,869]	-3	hSpCas9	negative selection	9009277
4627847	4627870	3	-	27260156	SKES1	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.1571577164553841	[453]	[517,587,503,425]	3	hSpCas9	negative selection	9066271
4639435	4639458	3	+	27260156	SKES1	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.25092665139819736	[159]	[332,189,84,172]	5	hSpCas9	negative selection	9066272
4639449	4639472	3	-	27260156	SKES1	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.30881120676411133	[1357]	[1611,1804,1448,1819]	6	hSpCas9	negative selection	9066273
4627767	4627790	3	-	27260156	SKES1	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	-0.023653431123665525	[537]	[609,461,573,469]	0	hSpCas9	negative selection	9130526
4521052	4521075	3	-	27260156	SKES1	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.20245466505592613	[289]	[276,381,395,276]	4	hSpCas9	negative selection	9130527
4521040	4521063	3	+	27260156	SKES1	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.22321327666924135	[770]	[638,925,584,524]	-5	hSpCas9	negative selection	9130528
4627847	4627870	3	-	27260156	TOV112D	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	-0.009165847089122055	[453]	[888,422,243,284]	0	hSpCas9	negative selection	9187522
4639435	4639458	3	+	27260156	TOV112D	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	0.17121920438383165	[159]	[400,148,135,49]	3	hSpCas9	negative selection	9187523
4639449	4639472	3	-	27260156	TOV112D	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.36848440839164875	[1357]	[2152,2047,1604,1331]	7	hSpCas9	negative selection	9187524
4627767	4627790	3	-	27260156	TOV112D	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	-0.010900806315474854	[537]	[647,660,558,316]	0	hSpCas9	negative selection	9251777
4521052	4521075	3	-	27260156	TOV112D	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.14303246051723584	[289]	[399,252,212,403]	2	hSpCas9	negative selection	9251778
4521040	4521063	3	+	27260156	TOV112D	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.04320762525416322	[770]	[686,1178,594,638]	-1	hSpCas9	negative selection	9251779
4627847	4627870	3	-	27260156	TC71	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	-0.2685788218240651	[453]	[375,416,389,435]	-6	hSpCas9	negative selection	9308773
4639435	4639458	3	+	27260156	TC71	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.44809512148493336	[159]	[119,130,125,125]	-8	hSpCas9	negative selection	9308774
4639449	4639472	3	-	27260156	TC71	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.3548988777052453	[1357]	[2089,1569,1754,2040]	8	hSpCas9	negative selection	9308775
4627767	4627790	3	-	27260156	TC71	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.021960039336755638	[537]	[531,541,652,615]	0	hSpCas9	negative selection	9373028
4521052	4521075	3	-	27260156	TC71	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.3657480730721576	[289]	[374,407,340,485]	8	hSpCas9	negative selection	9373029
4521040	4521063	3	+	27260156	TC71	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	-0.36897737521775636	[770]	[645,536,609,775]	-7	hSpCas9	negative selection	9373030
4627847	4627870	3	-	27260156	TC32	viability	GTTGAGTAGCACTGCGTCTGTGG	ITPR1	ENSG00000150995	0.10734094900051165	[453]	[471,332,420,633]	2	hSpCas9	negative selection	9430024
4639435	4639458	3	+	27260156	TC32	viability	CTGGGGACCGTAATCCAGTATGG	ITPR1	ENSG00000150995	-0.25152092865351205	[159]	[137,146,96,97]	-4	hSpCas9	negative selection	9430025
4639449	4639472	3	-	27260156	TC32	viability	CCTGGATCACATTGCCATACTGG	ITPR1	ENSG00000150995	0.35046006157332	[1357]	[1488,1353,2014,1744]	6	hSpCas9	negative selection	9430026
4627767	4627790	3	-	27260156	TC32	viability	TCATGGGACATAGCTTAAAGAGG	ITPR1	ENSG00000150995	0.09384323693587843	[537]	[468,443,561,708]	1	hSpCas9	negative selection	9494279
4521052	4521075	3	-	27260156	TC32	viability	TTGTTAAGGTCCCCGGTTTCTGG	ITPR1	ENSG00000150995	0.37568992058843853	[289]	[308,251,424,470]	6	hSpCas9	negative selection	9494280
4521040	4521063	3	+	27260156	TC32	viability	TGTGTTGTACAGCCAGAAACCGG	ITPR1	ENSG00000150995	0.03343672649482754	[770]	[561,591,1134,783]	0	hSpCas9	negative selection	9494281
4516543	4516566	3	+	27869803	HPAFII	viability after 27 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.9117299868642066	[415]	[345,465,NaN]	7	hSpCas9	negative selection	9584915
4521024	4521047	3	-	27869803	HPAFII	viability after 27 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.4913518019818409	[561]	[195,221,NaN]	-4	hSpCas9	negative selection	9584916
4627813	4627836	3	+	27869803	HPAFII	viability after 27 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.826164983152659	[378]	[211,470,NaN]	6	hSpCas9	negative selection	9584987
4642219	4642242	3	-	27869803	HPAFII	viability after 27 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	1.0550491407010552	[371]	[497,329,NaN]	8	hSpCas9	negative selection	9585017
4644202	4644225	3	+	27869803	HPAFII	viability after 27 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-0.9468886635404377	[315]	[53,112,NaN]	-6	hSpCas9	negative selection	9585018
4645394	4645417	3	+	27869803	HPAFII	viability after 27 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	0.3556054573856984	[567]	[410,357,NaN]	3	hSpCas9	negative selection	9585019
4516543	4516566	3	+	27869803	HPAFII	viability after 15 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.3132979258763906	[415]	[832,382,NaN]	3	hSpCas9	negative selection	9667364
4521024	4521047	3	-	27869803	HPAFII	viability after 15 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.2645942372721426	[561]	[725,363,NaN]	-3	hSpCas9	negative selection	9667365
4627813	4627836	3	+	27869803	HPAFII	viability after 15 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.6142746601875408	[378]	[1056,353,NaN]	7	hSpCas9	negative selection	9667436
4642219	4642242	3	-	27869803	HPAFII	viability after 15 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	0.4961063865063471	[371]	[857,380,NaN]	5	hSpCas9	negative selection	9667466
4644202	4644225	3	+	27869803	HPAFII	viability after 15 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-0.39168504060433346	[315]	[441,144,NaN]	-4	hSpCas9	negative selection	9667467
4645394	4645417	3	+	27869803	HPAFII	viability after 15 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	0.3126285226980752	[567]	[989,613,NaN]	3	hSpCas9	negative selection	9667468
4516543	4516566	3	+	27869803	ASPC1	viability after 36 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.5456471511237758	[1061]	[579,888,231]	5	hSpCas9	negative selection	9749813
4521024	4521047	3	-	27869803	ASPC1	viability after 36 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	0.04352220492291514	[1284]	[477,419,479]	0	hSpCas9	negative selection	9749814
4627813	4627836	3	+	27869803	ASPC1	viability after 36 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	-0.7539954891430644	[896]	[327,153,108]	-6	hSpCas9	negative selection	9749885
4642219	4642242	3	-	27869803	ASPC1	viability after 36 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	0.0569437398869716	[755]	[354,241,240]	0	hSpCas9	negative selection	9749915
4644202	4644225	3	+	27869803	ASPC1	viability after 36 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-0.5804213598906047	[962]	[330,191,173]	-5	hSpCas9	negative selection	9749916
4645394	4645417	3	+	27869803	ASPC1	viability after 36 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	0.6767768610998086	[1064]	[931,504,421]	6	hSpCas9	negative selection	9749917
4516543	4516566	3	+	27869803	PATU8988S	viability after 35 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.13186443320978047	[871]	[301,467,NaN]	1	hSpCas9	negative selection	9832262
4521024	4521047	3	-	27869803	PATU8988S	viability after 35 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	0.25300645743539985	[1322]	[624,644,NaN]	3	hSpCas9	negative selection	9832263
4627813	4627836	3	+	27869803	PATU8988S	viability after 35 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.614719932362614	[652]	[496,307,NaN]	6	hSpCas9	negative selection	9832334
4642219	4642242	3	-	27869803	PATU8988S	viability after 35 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	0.0701756675736146	[652]	[321,229,NaN]	0	hSpCas9	negative selection	9832364
4644202	4644225	3	+	27869803	PATU8988S	viability after 35 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	0.9478195496922114	[804]	[797,451,NaN]	8	hSpCas9	negative selection	9832365
4645394	4645417	3	+	27869803	PATU8988S	viability after 35 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	0.4025277126664627	[1012]	[663,413,NaN]	4	hSpCas9	negative selection	9832366
4516543	4516566	3	+	27869803	PATU8988S	viability after 31 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.046578457717392885	[871]	[326,399,NaN]	0	hSpCas9	negative selection	9914711
4521024	4521047	3	-	27869803	PATU8988S	viability after 31 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	0.15747101797680596	[1322]	[484,719,NaN]	2	hSpCas9	negative selection	9914712
4627813	4627836	3	+	27869803	PATU8988S	viability after 31 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.3547295327675914	[652]	[328,337,NaN]	4	hSpCas9	negative selection	9914783
4642219	4642242	3	-	27869803	PATU8988S	viability after 31 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	-0.2594123991201805	[652]	[257,165,NaN]	-3	hSpCas9	negative selection	9914813
4644202	4644225	3	+	27869803	PATU8988S	viability after 31 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	0.8026949146635728	[804]	[551,569,NaN]	8	hSpCas9	negative selection	9914814
4645394	4645417	3	+	27869803	PATU8988S	viability after 31 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	0.0978673794688023	[1012]	[426,438,NaN]	1	hSpCas9	negative selection	9914815
4516543	4516566	3	+	27869803	HPAFII	viability after 35 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	1.012135753437024	[415]	[404,446,NaN]	6	hSpCas9	negative selection	9997160
4521024	4521047	3	-	27869803	HPAFII	viability after 35 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.16383269326826388	[561]	[189,325,NaN]	-1	hSpCas9	negative selection	9997161
4627813	4627836	3	+	27869803	HPAFII	viability after 35 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.9985744531109717	[378]	[150,644,NaN]	6	hSpCas9	negative selection	9997232
4642219	4642242	3	-	27869803	HPAFII	viability after 35 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	1.432747718750389	[371]	[601,402,NaN]	8	hSpCas9	negative selection	9997262
4644202	4644225	3	+	27869803	HPAFII	viability after 35 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-1.095384723840597	[315]	[48,103,NaN]	-6	hSpCas9	negative selection	9997263
4645394	4645417	3	+	27869803	HPAFII	viability after 35 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	0.7093436049975421	[567]	[551,377,NaN]	5	hSpCas9	negative selection	9997264
4516543	4516566	3	+	27869803	HPAFII	viability after 31 days	TACGCGGAGGGATCGACAAATGG	ITPR1	ENSG00000150995	0.8292780931727315	[415]	[421,406,NaN]	6	hSpCas9	negative selection	10079609
4521024	4521047	3	-	27869803	HPAFII	viability after 31 days	CAACACAACGATCATCAACCAGG	ITPR1	ENSG00000150995	-0.40269126890364515	[561]	[206,272,NaN]	-3	hSpCas9	negative selection	10079610
4627813	4627836	3	+	27869803	HPAFII	viability after 31 days	TTCTGGAAAGCCGCTAAGCCTGG	ITPR1	ENSG00000150995	0.8226458076296095	[378]	[212,553,NaN]	6	hSpCas9	negative selection	10079681
4642219	4642242	3	-	27869803	HPAFII	viability after 31 days	ATGGATCGCAGCTTGTAGAATGG	ITPR1	ENSG00000150995	1.3476728720865352	[371]	[493,571,NaN]	8	hSpCas9	negative selection	10079711
4644202	4644225	3	+	27869803	HPAFII	viability after 31 days	CATCAACTGGTAGATAACCCAGG	ITPR1	ENSG00000150995	-1.3714751231533773	[315]	[35,103,NaN]	-7	hSpCas9	negative selection	10079712
4645394	4645417	3	+	27869803	HPAFII	viability after 31 days	CCGTCAACTGCAATACAAGCTGG	ITPR1	ENSG00000150995	0.6399380017674048	[567]	[579,405,NaN]	5	hSpCas9	negative selection	10079713
4768716	4768739	3	-	28162770	P31FUJ	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-0.9156120285336795	[60]	[37]	-6	hSpCas9	negative selection	10176522
4683402	4683425	3	+	28162770	P31FUJ	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	0.13898640499970827	[363]	[470]	1	hSpCas9	negative selection	10176523
4642164	4642187	3	+	28162770	P31FUJ	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	0.049597526286346394	[36]	[44]	0	hSpCas9	negative selection	10176524
4644165	4644188	3	-	28162770	P31FUJ	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	-0.5744935541231709	[146]	[115]	-5	hSpCas9	negative selection	10176525
4658238	4658261	3	+	28162770	P31FUJ	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	-0.2856540866801136	[555]	[535]	-3	hSpCas9	negative selection	10176526
4665188	4665211	3	+	28162770	P31FUJ	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	-0.9160667787473387	[166]	[103]	-6	hSpCas9	negative selection	10176527
4667495	4667518	3	-	28162770	P31FUJ	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	-1.2328022044143787	[21]	[10]	-7	hSpCas9	negative selection	10176528
4673280	4673303	3	-	28162770	P31FUJ	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	0.06675807744452922	[103]	[127]	0	hSpCas9	negative selection	10176529
4673346	4673369	3	-	28162770	P31FUJ	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	-0.44893563527914426	[344]	[296]	-4	hSpCas9	negative selection	10176530
4676729	4676752	3	+	28162770	P31FUJ	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	-1.1638548506968873	[285]	[149]	-7	hSpCas9	negative selection	10176531
4768716	4768739	3	-	28162770	TF1	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	NaN	[NaN]	[70]	1	hSpCas9	negative selection	10345888
4683402	4683425	3	+	28162770	TF1	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	NaN	[NaN]	[295]	1	hSpCas9	negative selection	10345889
4642164	4642187	3	+	28162770	TF1	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10345890
4644165	4644188	3	-	28162770	TF1	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10345891
4658238	4658261	3	+	28162770	TF1	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	NaN	[NaN]	[562]	1	hSpCas9	negative selection	10345892
4665188	4665211	3	+	28162770	TF1	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	NaN	[NaN]	[80]	1	hSpCas9	negative selection	10345893
4667495	4667518	3	-	28162770	TF1	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	NaN	[NaN]	[27]	1	hSpCas9	negative selection	10345894
4673280	4673303	3	-	28162770	TF1	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	NaN	[NaN]	[172]	1	hSpCas9	negative selection	10345895
4673346	4673369	3	-	28162770	TF1	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	NaN	[NaN]	[274]	1	hSpCas9	negative selection	10345896
4676729	4676752	3	+	28162770	TF1	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	NaN	[NaN]	[115]	1	hSpCas9	negative selection	10345897
4768716	4768739	3	-	28162770	SKM1	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	1.2934755193979304	[17]	[77]	9	hSpCas9	negative selection	10515254
4683402	4683425	3	+	28162770	SKM1	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	0.13276904798499678	[80]	[156]	1	hSpCas9	negative selection	10515255
4642164	4642187	3	+	28162770	SKM1	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	-1.4069641987431618	[8]	[5]	-7	hSpCas9	negative selection	10515256
4644165	4644188	3	-	28162770	SKM1	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	0.8114593203903409	[38]	[120]	7	hSpCas9	negative selection	10515257
4658238	4658261	3	+	28162770	SKM1	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	0.3459429392920661	[161]	[363]	3	hSpCas9	negative selection	10515258
4665188	4665211	3	+	28162770	SKM1	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	-1.179553702640089	[40]	[31]	-7	hSpCas9	negative selection	10515259
4667495	4667518	3	-	28162770	SKM1	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	-0.5589672921882118	[4]	[5]	-4	hSpCas9	negative selection	10515260
4673280	4673303	3	-	28162770	SKM1	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-0.8576256077527268	[40]	[39]	-6	hSpCas9	negative selection	10515261
4673346	4673369	3	-	28162770	SKM1	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	0.1885675436881819	[67]	[136]	1	hSpCas9	negative selection	10515262
4676729	4676752	3	+	28162770	SKM1	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	1.1072252275646137	[46]	[178]	8	hSpCas9	negative selection	10515263
4768716	4768739	3	-	28162770	SKM1	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	1.2934755193979304	[17]	[77]	9	hSpCas9	negative selection	10684620
4683402	4683425	3	+	28162770	SKM1	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	0.13276904798499678	[80]	[156]	1	hSpCas9	negative selection	10684621
4642164	4642187	3	+	28162770	SKM1	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	-1.4069641987431618	[8]	[5]	-7	hSpCas9	negative selection	10684622
4644165	4644188	3	-	28162770	SKM1	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	0.8114593203903409	[38]	[120]	7	hSpCas9	negative selection	10684623
4658238	4658261	3	+	28162770	SKM1	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	0.3459429392920661	[161]	[363]	3	hSpCas9	negative selection	10684624
4665188	4665211	3	+	28162770	SKM1	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	-1.179553702640089	[40]	[31]	-7	hSpCas9	negative selection	10684625
4667495	4667518	3	-	28162770	SKM1	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	-0.5589672921882118	[4]	[5]	-4	hSpCas9	negative selection	10684626
4673280	4673303	3	-	28162770	SKM1	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-0.8576256077527268	[40]	[39]	-6	hSpCas9	negative selection	10684627
4673346	4673369	3	-	28162770	SKM1	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	0.1885675436881819	[67]	[136]	1	hSpCas9	negative selection	10684628
4676729	4676752	3	+	28162770	SKM1	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	1.1072252275646137	[46]	[178]	8	hSpCas9	negative selection	10684629
4768716	4768739	3	-	28162770	PL21	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	0.25672314285568754	[74]	[38]	2	hSpCas9	negative selection	10853986
4683402	4683425	3	+	28162770	PL21	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	-0.03592774374420425	[211]	[89]	0	hSpCas9	negative selection	10853987
4642164	4642187	3	+	28162770	PL21	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	1.0366408822064408	[27]	[24]	8	hSpCas9	negative selection	10853988
4644165	4644188	3	-	28162770	PL21	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	-0.7998603855106798	[167]	[41]	-5	hSpCas9	negative selection	10853989
4658238	4658261	3	+	28162770	PL21	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	0.6275031269596774	[640]	[430]	5	hSpCas9	negative selection	10853990
4665188	4665211	3	+	28162770	PL21	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	-0.9773985710628674	[94]	[20]	-6	hSpCas9	negative selection	10853991
4667495	4667518	3	-	28162770	PL21	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	-0.9697853869529922	[8]	[1]	-6	hSpCas9	negative selection	10853992
4673280	4673303	3	-	28162770	PL21	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	1.084662397069384	[90]	[83]	8	hSpCas9	negative selection	10853993
4673346	4673369	3	-	28162770	PL21	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	1.132676646710581	[196]	[187]	8	hSpCas9	negative selection	10853994
4676729	4676752	3	+	28162770	PL21	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	-0.8086305951384121	[164]	[40]	-5	hSpCas9	negative selection	10853995
4768716	4768739	3	-	28162770	P31FUJ	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-0.9156120285336795	[60]	[37]	-6	hSpCas9	negative selection	11023352
4683402	4683425	3	+	28162770	P31FUJ	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	0.13898640499970827	[363]	[470]	1	hSpCas9	negative selection	11023353
4642164	4642187	3	+	28162770	P31FUJ	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	0.049597526286346394	[36]	[44]	0	hSpCas9	negative selection	11023354
4644165	4644188	3	-	28162770	P31FUJ	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	-0.5744935541231709	[146]	[115]	-5	hSpCas9	negative selection	11023355
4658238	4658261	3	+	28162770	P31FUJ	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	-0.2856540866801136	[555]	[535]	-3	hSpCas9	negative selection	11023356
4665188	4665211	3	+	28162770	P31FUJ	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	-0.9160667787473387	[166]	[103]	-6	hSpCas9	negative selection	11023357
4667495	4667518	3	-	28162770	P31FUJ	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	-1.2328022044143787	[21]	[10]	-7	hSpCas9	negative selection	11023358
4673280	4673303	3	-	28162770	P31FUJ	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	0.06675807744452922	[103]	[127]	0	hSpCas9	negative selection	11023359
4673346	4673369	3	-	28162770	P31FUJ	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	-0.44893563527914426	[344]	[296]	-4	hSpCas9	negative selection	11023360
4676729	4676752	3	+	28162770	P31FUJ	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	-1.1638548506968873	[285]	[149]	-7	hSpCas9	negative selection	11023361
4768716	4768739	3	-	28162770	OCIAML5	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-1.482832761198278	[47]	[30]	-7	hSpCas9	negative selection	11192718
4683402	4683425	3	+	28162770	OCIAML5	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	0.0074522055861726555	[193]	[351]	0	hSpCas9	negative selection	11192719
4642164	4642187	3	+	28162770	OCIAML5	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	-2.132174490056732	[16]	[6]	-8	hSpCas9	negative selection	11192720
4644165	4644188	3	-	28162770	OCIAML5	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	0.3501222797492699	[112]	[259]	3	hSpCas9	negative selection	11192721
4658238	4658261	3	+	28162770	OCIAML5	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	0.45844034494354013	[278]	[691]	4	hSpCas9	negative selection	11192722
4665188	4665211	3	+	28162770	OCIAML5	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	-0.10109411870391172	[81]	[137]	0	hSpCas9	negative selection	11192723
4667495	4667518	3	-	28162770	OCIAML5	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	-2.7265356887801384	[21]	[5]	-8	hSpCas9	negative selection	11192724
4673280	4673303	3	-	28162770	OCIAML5	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	1.6963700538320454	[19]	[116]	9	hSpCas9	negative selection	11192725
4673346	4673369	3	-	28162770	OCIAML5	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	-0.5214212588755256	[197]	[248]	-4	hSpCas9	negative selection	11192726
4676729	4676752	3	+	28162770	OCIAML5	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	-1.0744589922004453	[132]	[113]	-6	hSpCas9	negative selection	11192727
4768716	4768739	3	-	28162770	EOL1	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-1.5239127292457595	[130]	[23]	-7	hSpCas9	negative selection	11362084
4683402	4683425	3	+	28162770	EOL1	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	-0.8005923871988819	[323]	[97]	-5	hSpCas9	negative selection	11362085
4642164	4642187	3	+	28162770	EOL1	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	0.060202870928100616	[70]	[38]	0	hSpCas9	negative selection	11362086
4644165	4644188	3	-	28162770	EOL1	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	-0.8222656085520186	[244]	[72]	-5	hSpCas9	negative selection	11362087
4658238	4658261	3	+	28162770	EOL1	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	0.3382500601655589	[1080]	[719]	3	hSpCas9	negative selection	11362088
4665188	4665211	3	+	28162770	EOL1	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	0.40224930563154926	[213]	[148]	3	hSpCas9	negative selection	11362089
4667495	4667518	3	-	28162770	EOL1	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	-0.8409869747924423	[16]	[4]	-5	hSpCas9	negative selection	11362090
4673280	4673303	3	-	28162770	EOL1	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	0.29553009077144266	[132]	[85]	2	hSpCas9	negative selection	11362091
4673346	4673369	3	-	28162770	EOL1	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	0.5648533061354658	[357]	[278]	5	hSpCas9	negative selection	11362092
4676729	4676752	3	+	28162770	EOL1	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	-1.5882649433947862	[233]	[40]	-7	hSpCas9	negative selection	11362093
4768716	4768739	3	-	28162770	MOLM13	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-2.965070025731528	[107]	[9]	-8	hSpCas9	negative selection	11531450
4683402	4683425	3	+	28162770	MOLM13	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	1.1025390063660878	[370]	[575]	8	hSpCas9	negative selection	11531451
4642164	4642187	3	+	28162770	MOLM13	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	0.579782261615476	[61]	[66]	4	hSpCas9	negative selection	11531452
4644165	4644188	3	-	28162770	MOLM13	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	1.0204304045733577	[194]	[285]	7	hSpCas9	negative selection	11531453
4658238	4658261	3	+	28162770	MOLM13	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	0.5185710380184907	[894]	[926]	4	hSpCas9	negative selection	11531454
4665188	4665211	3	+	28162770	MOLM13	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	1.980443386737685	[142]	[407]	9	hSpCas9	negative selection	11531455
4667495	4667518	3	-	28162770	MOLM13	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	0.12685246370951164	[18]	[14]	0	hSpCas9	negative selection	11531456
4673280	4673303	3	-	28162770	MOLM13	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-0.9373670969416796	[195]	[73]	-5	hSpCas9	negative selection	11531457
4673346	4673369	3	-	28162770	MOLM13	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	-0.006266333290642689	[356]	[256]	0	hSpCas9	negative selection	11531458
4676729	4676752	3	+	28162770	MOLM13	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	-0.9451204363872827	[236]	[88]	-5	hSpCas9	negative selection	11531459
4768716	4768739	3	-	28162770	HEL	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-1.0851816225628421	[105]	[31]	-6	hSpCas9	negative selection	11700816
4683402	4683425	3	+	28162770	HEL	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	-1.0202261807220725	[360]	[113]	-6	hSpCas9	negative selection	11700817
4642164	4642187	3	+	28162770	HEL	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	-0.6051886814432286	[56]	[23]	-4	hSpCas9	negative selection	11700818
4644165	4644188	3	-	28162770	HEL	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	0.08292980850753898	[198]	[134]	0	hSpCas9	negative selection	11700819
4658238	4658261	3	+	28162770	HEL	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	0.10250077577725158	[793]	[545]	0	hSpCas9	negative selection	11700820
4665188	4665211	3	+	28162770	HEL	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	0.5760677923550692	[154]	[147]	5	hSpCas9	negative selection	11700821
4667495	4667518	3	-	28162770	HEL	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	-2.2641517636081616	[14]	[1]	-8	hSpCas9	negative selection	11700822
4673280	4673303	3	-	28162770	HEL	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-0.7558105444899178	[144]	[54]	-5	hSpCas9	negative selection	11700823
4673346	4673369	3	-	28162770	HEL	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	0.36537107515253375	[262]	[216]	3	hSpCas9	negative selection	11700824
4676729	4676752	3	+	28162770	HEL	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	-0.4861589011819006	[233]	[106]	-3	hSpCas9	negative selection	11700825
4768716	4768739	3	-	28162770	MV411	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-0.9881906977103665	[72]	[30]	-6	hSpCas9	negative selection	11870182
4683402	4683425	3	+	28162770	MV411	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	0.1303981295925562	[230]	[212]	1	hSpCas9	negative selection	11870183
4642164	4642187	3	+	28162770	MV411	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	0.6280415529977452	[52]	[68]	5	hSpCas9	negative selection	11870184
4644165	4644188	3	-	28162770	MV411	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	0.40383910812534207	[130]	[145]	3	hSpCas9	negative selection	11870185
4658238	4658261	3	+	28162770	MV411	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	-0.04379374688167048	[557]	[455]	0	hSpCas9	negative selection	11870186
4665188	4665211	3	+	28162770	MV411	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	-0.49232667673610425	[171]	[102]	-4	hSpCas9	negative selection	11870187
4667495	4667518	3	-	28162770	MV411	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	0.09543445733772504	[9]	[8]	0	hSpCas9	negative selection	11870188
4673280	4673303	3	-	28162770	MV411	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-0.6242383522416852	[85]	[46]	-4	hSpCas9	negative selection	11870189
4673346	4673369	3	-	28162770	MV411	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	-0.0065678892498926	[222]	[186]	0	hSpCas9	negative selection	11870190
4676729	4676752	3	+	28162770	MV411	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	-1.2047697410866094	[248]	[90]	-7	hSpCas9	negative selection	11870191
4768716	4768739	3	-	28162770	MONOMAC1	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-0.8751087521721914	[55]	[34]	-6	hSpCas9	negative selection	12039548
4683402	4683425	3	+	28162770	MONOMAC1	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	0.07956725731831849	[193]	[234]	0	hSpCas9	negative selection	12039549
4642164	4642187	3	+	28162770	MONOMAC1	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	0.037428406577469486	[33]	[39]	0	hSpCas9	negative selection	12039550
4644165	4644188	3	-	28162770	MONOMAC1	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	0.02973401478746851	[93]	[109]	0	hSpCas9	negative selection	12039551
4658238	4658261	3	+	28162770	MONOMAC1	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	0.4755447745027235	[361]	[576]	5	hSpCas9	negative selection	12039552
4665188	4665211	3	+	28162770	MONOMAC1	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	-0.7721515618243627	[72]	[48]	-6	hSpCas9	negative selection	12039553
4667495	4667518	3	-	28162770	MONOMAC1	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	1.5399287471066527	[8]	[29]	9	hSpCas9	negative selection	12039554
4673280	4673303	3	-	28162770	MONOMAC1	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-0.7577518015340325	[58]	[39]	-6	hSpCas9	negative selection	12039555
4673346	4673369	3	-	28162770	MONOMAC1	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	0.3307519452743685	[162]	[234]	3	hSpCas9	negative selection	12039556
4676729	4676752	3	+	28162770	MONOMAC1	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	-0.4631117072133985	[94]	[78]	-4	hSpCas9	negative selection	12039557
4768716	4768739	3	-	28162770	OCIAML2	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-1.3675363322780576	[26]	[57]	-7	hSpCas9	negative selection	12208914
4683402	4683425	3	+	28162770	OCIAML2	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	0.28069106190111487	[44]	[302]	2	hSpCas9	negative selection	12208915
4642164	4642187	3	+	28162770	OCIAML2	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	0.766409372058688	[6]	[65]	7	hSpCas9	negative selection	12208916
4644165	4644188	3	-	28162770	OCIAML2	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	0.15664348033695932	[27]	[172]	1	hSpCas9	negative selection	12208917
4658238	4658261	3	+	28162770	OCIAML2	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	-0.5645213901520632	[122]	[460]	-4	hSpCas9	negative selection	12208918
4665188	4665211	3	+	28162770	OCIAML2	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	1.094154793541365	[17]	[212]	9	hSpCas9	negative selection	12208919
4667495	4667518	3	-	28162770	OCIAML2	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	-1.2862052541047337	[10]	[24]	-7	hSpCas9	negative selection	12208920
4673280	4673303	3	-	28162770	OCIAML2	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-0.770190107101069	[15]	[51]	-5	hSpCas9	negative selection	12208921
4673346	4673369	3	-	28162770	OCIAML2	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	-0.7123357216354431	[46]	[158]	-5	hSpCas9	negative selection	12208922
4676729	4676752	3	+	28162770	OCIAML2	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	0.15685729212555202	[38]	[240]	1	hSpCas9	negative selection	12208923
4768716	4768739	3	-	28162770	OCIAML3	viability	ACAGGAGCTGAAGGAAGCGGAGG	ITPR1	ENSG00000150995	-1.6720101523254363	[18]	[17]	-8	hSpCas9	negative selection	12378280
4683402	4683425	3	+	28162770	OCIAML3	viability	CTGGACTTGGATGACCACGGCGG	ITPR1	ENSG00000150995	0.777440590406998	[62]	[325]	7	hSpCas9	negative selection	12378281
4642164	4642187	3	+	28162770	OCIAML3	viability	CATGAGAGTCACATTGGACGAGG	ITPR1	ENSG00000150995	0.1974057378644194	[12]	[44]	1	hSpCas9	negative selection	12378282
4644165	4644188	3	-	28162770	OCIAML3	viability	GGGGCTGACCAGCATTGACGGGG	ITPR1	ENSG00000150995	0.021328509440511817	[46]	[143]	0	hSpCas9	negative selection	12378283
4658238	4658261	3	+	28162770	OCIAML3	viability	GATCCCACCACTCTGCGTGGAGG	ITPR1	ENSG00000150995	0.5614902904828696	[133]	[596]	5	hSpCas9	negative selection	12378284
4665188	4665211	3	+	28162770	OCIAML3	viability	GCTTCGGCTGGAAGAGCTCGGGG	ITPR1	ENSG00000150995	-0.009045139603006902	[29]	[89]	0	hSpCas9	negative selection	12378285
4667495	4667518	3	-	28162770	OCIAML3	viability	AAATGTGTCAATCTCTGCCGCGG	ITPR1	ENSG00000150995	-2.1789701410453195	[8]	[5]	-8	hSpCas9	negative selection	12378286
4673280	4673303	3	-	28162770	OCIAML3	viability	CATGCATGTGAAGCATGAGGCGG	ITPR1	ENSG00000150995	-1.4013625623817672	[34]	[39]	-7	hSpCas9	negative selection	12378287
4673346	4673369	3	-	28162770	OCIAML3	viability	AGGGAATCTCCGACCAGAGGCGG	ITPR1	ENSG00000150995	0.47208155013360936	[63]	[267]	4	hSpCas9	negative selection	12378288
4676729	4676752	3	+	28162770	OCIAML3	viability	GAAGCAGGCAGAGCCTGAGAAGG	ITPR1	ENSG00000150995	0.042793791916611035	[81]	[254]	0	hSpCas9	negative selection	12378289