Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 3419
• Symbol: Idh3a
• Description: isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha

DataSource: http://genomecrispr.dkfz.de/#!/results/Idh3a

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
78160084	78160107	15	+	26472758	Jiyoye	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-1.6594956581394145	[154]	[36]	-8	hSpCas9	negative selection	75779
78160145	78160168	15	+	26472758	Jiyoye	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-1.2340945601172368	[208]	[66]	-7	hSpCas9	negative selection	75780
78160122	78160145	15	+	26472758	Jiyoye	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	-0.580187792816201	[340]	[171]	-4	hSpCas9	negative selection	75781
78162254	78162277	15	+	26472758	Jiyoye	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	-1.177787119215283	[173]	[57]	-7	hSpCas9	negative selection	75782
78162310	78162333	15	+	26472758	Jiyoye	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-1.0538745155298066	[222]	[80]	-6	hSpCas9	negative selection	75783
78162326	78162349	15	+	26472758	Jiyoye	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-0.0078621177729703	[23]	[17]	0	hSpCas9	negative selection	75784
78149414	78149437	15	-	26472758	Jiyoye	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-1.1217530843009547	[100]	[34]	-6	hSpCas9	negative selection	75785
78161733	78161756	15	+	26472758	Jiyoye	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	-0.41137774715659475	[96]	[54]	-3	hSpCas9	negative selection	75786
78155240	78155263	15	+	26472758	Jiyoye	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	-5.400179540551731	[55]	[0]	-9	hSpCas9	negative selection	75787
78155252	78155275	15	+	26472758	Jiyoye	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	-1.1685093056272722	[154]	[51]	-7	hSpCas9	negative selection	75788
78160084	78160107	15	+	26472758	KBM7	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.3204234828694321	[275,122]	[118,30]	-3	hSpCas9	negative selection	266897
78160145	78160168	15	+	26472758	KBM7	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.663920336379777	[634,483]	[87,232]	-5	hSpCas9	negative selection	266898
78160122	78160145	15	+	26472758	KBM7	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	-0.7652110763383775	[1297,775]	[282,278]	-6	hSpCas9	negative selection	266899
78162254	78162277	15	+	26472758	KBM7	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	-1.2461457540241916	[432,332]	[88,62]	-7	hSpCas9	negative selection	266900
78162310	78162333	15	+	26472758	KBM7	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-1.7752599051929074	[528,504]	[76,65]	-8	hSpCas9	negative selection	266901
78162326	78162349	15	+	26472758	KBM7	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-2.392656202774349	[153,194]	[17,13]	-9	hSpCas9	negative selection	266902
78149414	78149437	15	-	26472758	KBM7	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-0.026952986126568712	[233,285]	[68,168]	0	hSpCas9	negative selection	266903
78161733	78161756	15	+	26472758	KBM7	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	-1.2263340340792959	[371,231]	[86,34]	-7	hSpCas9	negative selection	266904
78155240	78155263	15	+	26472758	KBM7	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	0.7462300107175421	[4,21]	[22,0]	7	hSpCas9	negative selection	266905
78155252	78155275	15	+	26472758	KBM7	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	0.30833065765714485	[603,490]	[298,332]	3	hSpCas9	negative selection	266906
78160084	78160107	15	+	26472758	Raji	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-1.3317280988841016	[140]	[12]	-7	hSpCas9	negative selection	458015
78160145	78160168	15	+	26472758	Raji	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-1.4925293068135284	[290]	[23]	-8	hSpCas9	negative selection	458016
78160122	78160145	15	+	26472758	Raji	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	0.07029421663837943	[393]	[95]	0	hSpCas9	negative selection	458017
78162254	78162277	15	+	26472758	Raji	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	-0.6169820220129734	[151]	[22]	-5	hSpCas9	negative selection	458018
78162310	78162333	15	+	26472758	Raji	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.6784916592735533	[199]	[28]	-5	hSpCas9	negative selection	458019
78162326	78162349	15	+	26472758	Raji	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-1.647503966789869	[107]	[7]	-8	hSpCas9	negative selection	458020
78149414	78149437	15	-	26472758	Raji	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-1.1445348382660203	[180]	[18]	-7	hSpCas9	negative selection	458021
78161733	78161756	15	+	26472758	Raji	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	-2.0784830099377345	[181]	[9]	-8	hSpCas9	negative selection	458022
78155240	78155263	15	+	26472758	Raji	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	-2.214544559513763	[19]	[0]	-8	hSpCas9	negative selection	458023
78155252	78155275	15	+	26472758	Raji	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	-0.8360329362600332	[299]	[38]	-6	hSpCas9	negative selection	458024
78160084	78160107	15	+	26472758	K562	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.3817664357812225	[141]	[91]	-3	hSpCas9	negative selection	649133
78160145	78160168	15	+	26472758	K562	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-1.9419943965644346	[527]	[115]	-7	hSpCas9	negative selection	649134
78160122	78160145	15	+	26472758	K562	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	-1.4673849199430293	[700]	[213]	-6	hSpCas9	negative selection	649135
78162254	78162277	15	+	26472758	K562	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	-3.529769330455958	[300]	[21]	-8	hSpCas9	negative selection	649136
78162310	78162333	15	+	26472758	K562	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-2.7519700187811744	[398]	[49]	-8	hSpCas9	negative selection	649137
78162326	78162349	15	+	26472758	K562	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-2.9552536171699177	[146]	[15]	-8	hSpCas9	negative selection	649138
78149414	78149437	15	-	26472758	K562	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-1.3127987825718046	[205]	[69]	-6	hSpCas9	negative selection	649139
78161733	78161756	15	+	26472758	K562	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	-3.0847048686251193	[200]	[19]	-8	hSpCas9	negative selection	649140
78155240	78155263	15	+	26472758	K562	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	-4.147898695112312	[20]	[0]	-9	hSpCas9	negative selection	649141
78155252	78155275	15	+	26472758	K562	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	-0.3108608572610205	[456]	[310]	-2	hSpCas9	negative selection	649142
78161667	78161690	15	-	26627737	DLD1	viability	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-2.142920352856308	[266]	[12,1,37]	-9	hSpCas9	negative selection	791929
78161722	78161745	15	-	26627737	DLD1	viability	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-2.7692533104312234	[350]	[24,24,0]	-9	hSpCas9	negative selection	791930
78162310	78162333	15	+	26627737	DLD1	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-4.257525300418994	[173]	[0,6,0]	-9	hSpCas9	negative selection	791931
78162326	78162349	15	+	26627737	DLD1	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-2.1414866044195264	[1332]	[46,140,96]	-9	hSpCas9	negative selection	791932
78165017	78165040	15	+	26627737	DLD1	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.468266382247629	[262]	[19,18,46]	-8	hSpCas9	negative selection	791933
78166218	78166241	15	+	26627737	DLD1	viability	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	1.052065202649381	[927]	[385,1044,420]	8	hSpCas9	negative selection	791934
78161667	78161690	15	-	26627737	GBM cells	viability after 5 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-0.3255800690960499	[228]	[110,84]	-5	hSpCas9	negative selection	874244
78161722	78161745	15	-	26627737	GBM cells	viability after 5 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-0.10108612511431442	[191]	[89,101]	-1	hSpCas9	negative selection	874245
78162310	78162333	15	+	26627737	GBM cells	viability after 5 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	0.5343414425898295	[102]	[66,92]	7	hSpCas9	negative selection	874246
78162326	78162349	15	+	26627737	GBM cells	viability after 5 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-0.10703539144550078	[485]	[197,285]	-2	hSpCas9	negative selection	874247
78165017	78165040	15	+	26627737	GBM cells	viability after 5 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.07154184950029896	[144]	[80,66]	-1	hSpCas9	negative selection	874248
78166218	78166241	15	+	26627737	GBM cells	viability after 5 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	0.8177065595504958	[337]	[408,229]	9	hSpCas9	negative selection	874249
78161667	78161690	15	-	26627737	GBM cells	viability after 13 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-0.04817829035780613	[228]	[112,125]	0	hSpCas9	negative selection	956559
78161722	78161745	15	-	26627737	GBM cells	viability after 13 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	0.11863325889641413	[191]	[111,113]	1	hSpCas9	negative selection	956560
78162310	78162333	15	+	26627737	GBM cells	viability after 13 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	0.4463190050450009	[102]	[95,59]	5	hSpCas9	negative selection	956561
78162326	78162349	15	+	26627737	GBM cells	viability after 13 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-0.2631831308995958	[485]	[211,225]	-3	hSpCas9	negative selection	956562
78165017	78165040	15	+	26627737	GBM cells	viability after 13 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.3087872064798045	[144]	[57,67]	-4	hSpCas9	negative selection	956563
78166218	78166241	15	+	26627737	GBM cells	viability after 13 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	0.8095686219328913	[337]	[348,298]	8	hSpCas9	negative selection	956564
78161667	78161690	15	-	26627737	GBM cells	viability after 21 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-0.8651568150785574	[228]	[72,63]	-6	hSpCas9	negative selection	1038874
78161722	78161745	15	-	26627737	GBM cells	viability after 21 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	0.054160231615467125	[191]	[112,103]	0	hSpCas9	negative selection	1038875
78162310	78162333	15	+	26627737	GBM cells	viability after 21 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	0.26817160611063806	[102]	[69,64]	3	hSpCas9	negative selection	1038876
78162326	78162349	15	+	26627737	GBM cells	viability after 21 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	0.7080058679558361	[485]	[423,437]	7	hSpCas9	negative selection	1038877
78165017	78165040	15	+	26627737	GBM cells	viability after 21 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.305448084076982	[144]	[57,68]	-3	hSpCas9	negative selection	1038878
78166218	78166241	15	+	26627737	GBM cells	viability after 21 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	0.33047822622022693	[337]	[244,217]	3	hSpCas9	negative selection	1038879
78161667	78161690	15	-	26627737	RPE1	viability after 9 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	0.5291986409390893	[488]	[216,225]	3	hSpCas9	negative selection	1121189
78161722	78161745	15	-	26627737	RPE1	viability after 9 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	0.36705630715604703	[613]	[205,301]	2	hSpCas9	negative selection	1121190
78162310	78162333	15	+	26627737	RPE1	viability after 9 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	0.17970355596094523	[356]	[171,67]	1	hSpCas9	negative selection	1121191
78162326	78162349	15	+	26627737	RPE1	viability after 9 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	0.5796298620038645	[1187]	[595,503]	4	hSpCas9	negative selection	1121192
78165017	78165040	15	+	26627737	RPE1	viability after 9 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.04607001202342226	[613]	[90,308]	0	hSpCas9	negative selection	1121193
78166218	78166241	15	+	26627737	RPE1	viability after 9 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	1.7559026330622514	[735]	[727,842]	8	hSpCas9	negative selection	1121194
78161667	78161690	15	-	26627737	RPE1	viability after 12 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-0.292649325393188	[488]	[98,115]	-2	hSpCas9	negative selection	1203504
78161722	78161745	15	-	26627737	RPE1	viability after 12 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	0.33959958772001014	[613]	[148,271]	2	hSpCas9	negative selection	1203505
78162310	78162333	15	+	26627737	RPE1	viability after 12 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	0.0659466067074479	[356]	[181,13]	0	hSpCas9	negative selection	1203506
78162326	78162349	15	+	26627737	RPE1	viability after 12 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	0.6602984745743683	[1187]	[552,452]	4	hSpCas9	negative selection	1203507
78165017	78165040	15	+	26627737	RPE1	viability after 12 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.1316792041174313	[613]	[33,118]	-7	hSpCas9	negative selection	1203508
78166218	78166241	15	+	26627737	RPE1	viability after 12 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	2.045025311235527	[735]	[935,688]	9	hSpCas9	negative selection	1203509
78161667	78161690	15	-	26627737	RPE1	viability after 15 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-1.0438565891340443	[488]	[89,44]	-6	hSpCas9	negative selection	1285819
78161722	78161745	15	-	26627737	RPE1	viability after 15 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	0.17476349268528038	[613]	[192,198]	1	hSpCas9	negative selection	1285820
78162310	78162333	15	+	26627737	RPE1	viability after 15 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.6753732869307221	[356]	[49,75]	-4	hSpCas9	negative selection	1285821
78162326	78162349	15	+	26627737	RPE1	viability after 15 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	1.3010113166258268	[1187]	[1049,613]	7	hSpCas9	negative selection	1285822
78165017	78165040	15	+	26627737	RPE1	viability after 15 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.8861043973518454	[613]	[38,146]	-5	hSpCas9	negative selection	1285823
78166218	78166241	15	+	26627737	RPE1	viability after 15 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	2.2011553677157636	[735]	[1328,598]	9	hSpCas9	negative selection	1285824
78161667	78161690	15	-	26627737	RPE1	viability after 18 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-1.649915330405429	[488]	[28,55]	-7	hSpCas9	negative selection	1368134
78161722	78161745	15	-	26627737	RPE1	viability after 18 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	0.5324113255618403	[613]	[287,187]	3	hSpCas9	negative selection	1368135
78162310	78162333	15	+	26627737	RPE1	viability after 18 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.9111322900135295	[356]	[57,43]	-5	hSpCas9	negative selection	1368136
78162326	78162349	15	+	26627737	RPE1	viability after 18 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	0.9048172382522415	[1187]	[782,404]	5	hSpCas9	negative selection	1368137
78165017	78165040	15	+	26627737	RPE1	viability after 18 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.2877819018250032	[613]	[63,71]	-7	hSpCas9	negative selection	1368138
78166218	78166241	15	+	26627737	RPE1	viability after 18 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	1.8053906818525673	[735]	[773,608]	8	hSpCas9	negative selection	1368139
78161667	78161690	15	-	26627737	HeLa	viability after 8 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-1.099077126964857	[323]	[52,36,101]	-8	hSpCas9	negative selection	1450449
78161722	78161745	15	-	26627737	HeLa	viability after 8 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-1.3018013803680553	[399]	[76,106,31]	-8	hSpCas9	negative selection	1450450
78162310	78162333	15	+	26627737	HeLa	viability after 8 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	0.5763497603379706	[92]	[21,51,95]	5	hSpCas9	negative selection	1450451
78162326	78162349	15	+	26627737	HeLa	viability after 8 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-0.1173371175037971	[550]	[231,204,227]	-1	hSpCas9	negative selection	1450452
78165017	78165040	15	+	26627737	HeLa	viability after 8 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	1.0763499090107407	[160]	[297,85,95]	7	hSpCas9	negative selection	1450453
78166218	78166241	15	+	26627737	HeLa	viability after 8 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	0.17348465470988983	[811]	[313,451,409]	1	hSpCas9	negative selection	1450454
78161667	78161690	15	-	26627737	HeLa	viability after 12 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-1.0715646944773183	[323]	[143,1,53]	-7	hSpCas9	negative selection	1532764
78161722	78161745	15	-	26627737	HeLa	viability after 12 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-1.7584948742822089	[399]	[59,28,59]	-9	hSpCas9	negative selection	1532765
78162310	78162333	15	+	26627737	HeLa	viability after 12 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.036946981660490597	[92]	[19,7,86]	0	hSpCas9	negative selection	1532766
78162326	78162349	15	+	26627737	HeLa	viability after 12 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-0.2604886809359921	[550]	[114,190,261]	-2	hSpCas9	negative selection	1532767
78165017	78165040	15	+	26627737	HeLa	viability after 12 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	0.23849449767680153	[160]	[96,40,101]	2	hSpCas9	negative selection	1532768
78166218	78166241	15	+	26627737	HeLa	viability after 12 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	-0.3236429475886019	[811]	[207,415,162]	-3	hSpCas9	negative selection	1532769
78161667	78161690	15	-	26627737	HeLa	viability after 15 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-1.9307056769370086	[323]	[25,17,61]	-9	hSpCas9	negative selection	1615079
78161722	78161745	15	-	26627737	HeLa	viability after 15 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-1.3218820336760735	[399]	[127,44,17]	-8	hSpCas9	negative selection	1615080
78162310	78162333	15	+	26627737	HeLa	viability after 15 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.5411572597124366	[92]	[16,0,62]	-5	hSpCas9	negative selection	1615081
78162326	78162349	15	+	26627737	HeLa	viability after 15 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-0.4461595860556165	[550]	[127,97,276]	-4	hSpCas9	negative selection	1615082
78165017	78165040	15	+	26627737	HeLa	viability after 15 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-2.051316126923643	[160]	[14,9,22]	-9	hSpCas9	negative selection	1615083
78166218	78166241	15	+	26627737	HeLa	viability after 15 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	-0.8176555698803781	[811]	[34,409,113]	-6	hSpCas9	negative selection	1615084
78161667	78161690	15	-	26627737	HeLa	viability after 18 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-1.891972657871919	[323]	[19,13,61]	-9	hSpCas9	negative selection	1697394
78161722	78161745	15	-	26627737	HeLa	viability after 18 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-1.3716081806956015	[399]	[80,37,17]	-8	hSpCas9	negative selection	1697395
78162310	78162333	15	+	26627737	HeLa	viability after 18 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.5777890005550126	[92]	[9,0,62]	-5	hSpCas9	negative selection	1697396
78162326	78162349	15	+	26627737	HeLa	viability after 18 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-0.45248491388729983	[550]	[82,82,276]	-4	hSpCas9	negative selection	1697397
78165017	78165040	15	+	26627737	HeLa	viability after 18 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-2.0839860927111964	[160]	[7,9,22]	-9	hSpCas9	negative selection	1697398
78166218	78166241	15	+	26627737	HeLa	viability after 18 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	-0.8155857622702071	[811]	[25,336,113]	-6	hSpCas9	negative selection	1697399
78161667	78161690	15	-	26627737	HCT116	viability after 6 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-2.4099422207897856	[500]	[28,6]	-8	hSpCas9	negative selection	1779709
78161722	78161745	15	-	26627737	HCT116	viability after 6 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-1.036976599511712	[506]	[43,35]	-5	hSpCas9	negative selection	1779710
78162310	78162333	15	+	26627737	HCT116	viability after 6 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-5.290741674880514	[248]	[0,0]	-9	hSpCas9	negative selection	1779711
78162326	78162349	15	+	26627737	HCT116	viability after 6 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-4.511906051983896	[1702]	[3,15]	-9	hSpCas9	negative selection	1779712
78165017	78165040	15	+	26627737	HCT116	viability after 6 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	0.5001572425963955	[236]	[4,78]	3	hSpCas9	negative selection	1779713
78166218	78166241	15	+	26627737	HCT116	viability after 6 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	1.76694311545479	[1142]	[461,693]	8	hSpCas9	negative selection	1779714
78161667	78161690	15	-	26627737	HCT116	viability after 8 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-3.475550564664766	[236]	[2,14,16]	-9	hSpCas9	negative selection	1862024
78161722	78161745	15	-	26627737	HCT116	viability after 8 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-0.41136795429318734	[234]	[124,103,63]	-5	hSpCas9	negative selection	1862025
78162310	78162333	15	+	26627737	HCT116	viability after 8 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-3.6870683894046947	[201]	[10,8,5]	-9	hSpCas9	negative selection	1862026
78162326	78162349	15	+	26627737	HCT116	viability after 8 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-2.791662800188441	[581]	[53,31,52]	-9	hSpCas9	negative selection	1862027
78165017	78165040	15	+	26627737	HCT116	viability after 8 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.3824236432183419	[156]	[49,28,20]	-9	hSpCas9	negative selection	1862028
78166218	78166241	15	+	26627737	HCT116	viability after 8 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	0.26989736163283284	[574]	[317,368,456]	3	hSpCas9	negative selection	1862029
78161667	78161690	15	-	26627737	HCT116	viability after 9 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-1.683167165691167	[500]	[1,72]	-8	hSpCas9	negative selection	1944339
78161722	78161745	15	-	26627737	HCT116	viability after 9 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	0.30859996343449897	[506]	[208,134]	2	hSpCas9	negative selection	1944340
78162310	78162333	15	+	26627737	HCT116	viability after 9 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-6.055012120714613	[248]	[0,0]	-9	hSpCas9	negative selection	1944341
78162326	78162349	15	+	26627737	HCT116	viability after 9 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-7.301360679787817	[1702]	[3,1]	-9	hSpCas9	negative selection	1944342
78165017	78165040	15	+	26627737	HCT116	viability after 9 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.2923399951929915	[236]	[55,1]	-7	hSpCas9	negative selection	1944343
78166218	78166241	15	+	26627737	HCT116	viability after 9 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	1.3092585160901713	[1142]	[714,788]	8	hSpCas9	negative selection	1944344
78161667	78161690	15	-	26627737	HCT116	viability after 12 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-5.981409938855158	[236]	[0,1,2]	-9	hSpCas9	negative selection	2026654
78161722	78161745	15	-	26627737	HCT116	viability after 12 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-0.569994508252295	[234]	[67,86,95]	-6	hSpCas9	negative selection	2026655
78162310	78162333	15	+	26627737	HCT116	viability after 12 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-2.7682034261147677	[201]	[31,2,9]	-9	hSpCas9	negative selection	2026656
78162326	78162349	15	+	26627737	HCT116	viability after 12 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-4.6828319233872975	[581]	[0,24,10]	-9	hSpCas9	negative selection	2026657
78165017	78165040	15	+	26627737	HCT116	viability after 12 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.6182867521263824	[156]	[13,36,30]	-9	hSpCas9	negative selection	2026658
78166218	78166241	15	+	26627737	HCT116	viability after 12 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	0.3225578166826064	[574]	[547,306,261]	3	hSpCas9	negative selection	2026659
78161667	78161690	15	-	26627737	HCT116	viability after 15 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-4.823899656580862	[236]	[0,11,0]	-9	hSpCas9	negative selection	2108969
78161722	78161745	15	-	26627737	HCT116	viability after 15 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-1.5832872969841927	[234]	[52,30,51]	-8	hSpCas9	negative selection	2108970
78162310	78162333	15	+	26627737	HCT116	viability after 15 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-6.858074653608561	[201]	[0,0,0]	-9	hSpCas9	negative selection	2108971
78162326	78162349	15	+	26627737	HCT116	viability after 15 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-2.685357619403568	[581]	[49,82,22]	-9	hSpCas9	negative selection	2108972
78165017	78165040	15	+	26627737	HCT116	viability after 15 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-2.543918893320532	[156]	[27,11,7]	-9	hSpCas9	negative selection	2108973
78166218	78166241	15	+	26627737	HCT116	viability after 15 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	0.5359076489620984	[574]	[690,446,325]	5	hSpCas9	negative selection	2108974
78161667	78161690	15	-	26627737	HCT116	viability after 18 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-6.840190873242838	[236]	[0,0,0]	-9	hSpCas9	negative selection	2191284
78161722	78161745	15	-	26627737	HCT116	viability after 18 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-1.8405587225172746	[234]	[37,21,35]	-9	hSpCas9	negative selection	2191285
78162310	78162333	15	+	26627737	HCT116	viability after 18 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-3.133310449496356	[201]	[21,9,0]	-9	hSpCas9	negative selection	2191286
78162326	78162349	15	+	26627737	HCT116	viability after 18 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-4.130206588098594	[581]	[0,23,22]	-9	hSpCas9	negative selection	2191287
78165017	78165040	15	+	26627737	HCT116	viability after 18 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-3.2710110202034017	[156]	[15,0,6]	-9	hSpCas9	negative selection	2191288
78166218	78166241	15	+	26627737	HCT116	viability after 18 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	0.3127800754368939	[574]	[567,166,310]	2	hSpCas9	negative selection	2191289
78149280	78149303	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCGCCCCCTAGACCGCCTCAGG	IDH3A	ENSG00000166411	-0.9858196647739752	[114,505]	[8,61]	-6	dCas9-VP64	positive selection	2438243
78149203	78149226	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGCTCGTCTCTCTGTGACTGG	IDH3A	ENSG00000166411	-0.008131067502063716	[206,54]	[43,10]	0	dCas9-VP64	positive selection	2438244
78149228	78149251	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GATTCGCCAGCGGAATGTCCAGG	IDH3A	ENSG00000166411	0.5616692611049664	[4,54]	[8,9]	2	dCas9-VP64	positive selection	2438245
78131657	78131680	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGTCCAGGTCGCACGGCGTGAGG	IDH3A	ENSG00000166411	1.3242315288030797	[14,13]	[4,9]	5	dCas9-VP64	positive selection	2439935
78131688	78131711	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTGGGAAAAAACCCTCTCGAGG	IDH3A	ENSG00000166411	4.062037518350581	[107,36]	[9,538]	9	dCas9-VP64	positive selection	2439936
78131604	78131627	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGCGACTCCGCCCCGCAGCAGG	IDH3A	ENSG00000166411	1.5954018175994773	[5,33]	[3,23]	6	dCas9-VP64	positive selection	2439937
78144078	78144101	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCCTGTAATCCCAGCACTTGGG	IDH3A	ENSG00000166411	-1.262579619046977	[170,274]	[19,19]	-7	dCas9-VP64	positive selection	2446350
78134436	78134459	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGTGCCATTGCACTCCAGCCGGG	IDH3A	ENSG00000166411	-0.5971814264096912	[233,130]	[36,14]	-3	dCas9-VP64	positive selection	2447001
78164286	78164309	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGAGAGAGAGAGAGAGAGAAG	IDH3A	ENSG00000166411	0.5483491143916677	[0,22]	[1,5]	2	dCas9-VP64	positive selection	2467751
78149280	78149303	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCGCCCCCTAGACCGCCTCAGG	IDH3A	ENSG00000166411	2.978346250048483	[28,130]	[14,379]	9	dCas9-VP64	positive selection	2533498
78149203	78149226	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGCTCGTCTCTCTGTGACTGG	IDH3A	ENSG00000166411	-1.1324409437967085	[481,148]	[60,33]	-9	dCas9-VP64	positive selection	2533499
78149228	78149251	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GATTCGCCAGCGGAATGTCCAGG	IDH3A	ENSG00000166411	0.2592897749347629	[95,32]	[8,39]	2	dCas9-VP64	positive selection	2533500
78131657	78131680	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGTCCAGGTCGCACGGCGTGAGG	IDH3A	ENSG00000166411	0.363322523970137	[285,497]	[98,224]	3	dCas9-VP64	positive selection	2535190
78131688	78131711	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTGGGAAAAAACCCTCTCGAGG	IDH3A	ENSG00000166411	0.2624737166174206	[36,93]	[18,29]	2	dCas9-VP64	positive selection	2535191
78131604	78131627	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGCGACTCCGCCCCGCAGCAGG	IDH3A	ENSG00000166411	-0.7600942725814013	[119,96]	[19,20]	-7	dCas9-VP64	positive selection	2535192
78144078	78144101	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCCTGTAATCCCAGCACTTGGG	IDH3A	ENSG00000166411	0.31922581039074327	[700,765]	[259,334]	2	dCas9-VP64	positive selection	2541605
78134436	78134459	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGTGCCATTGCACTCCAGCCGGG	IDH3A	ENSG00000166411	0.14726127288975888	[140,101]	[59,28]	1	dCas9-VP64	positive selection	2542256
78164286	78164309	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGAGAGAGAGAGAGAGAGAAG	IDH3A	ENSG00000166411	1.0596624284276592	[241,16]	[155,26]	6	dCas9-VP64	positive selection	2563006
78161612	78161635	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCAGTAAATTCATAGATGGG	IDH3A	ENSG00000166411	-0.11604653665470172	[4,4]	[4,3]	-2	hSpCas9	positive selection	2994718
78149414	78149437	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-0.40325674422831465	[3,3]	[3,0]	-5	hSpCas9	positive selection	2994719
78157558	78157581	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAACTTTAATTCCAGGAGATGG	IDH3A	ENSG00000166411	0.34214778343868	[2,2]	[3,3]	7	hSpCas9	positive selection	2994720
78162257	78162280	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTATCAAGCTCATCACCGAGGGG	IDH3A	ENSG00000166411	-1.164965735998791	[2,2]	[0,0]	-9	hSpCas9	positive selection	2994721
78161612	78161635	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCAGTAAATTCATAGATGGG	IDH3A	ENSG00000166411	0.36283204188087065	[4,4]	[4,4]	6	hSpCas9	positive selection	3062576
78149414	78149437	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	0.1782815866616744	[3,3]	[3,1]	3	hSpCas9	positive selection	3062577
78157558	78157581	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAACTTTAATTCCAGGAGATGG	IDH3A	ENSG00000166411	0.06744401945782327	[2,2]	[1,1]	1	hSpCas9	positive selection	3062578
78162257	78162280	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTATCAAGCTCATCACCGAGGGG	IDH3A	ENSG00000166411	0.10871306325626684	[2,2]	[2,1]	2	hSpCas9	positive selection	3062579
78155206	78155229		+	24336571	A375	resistance to PLX after 7 days	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.1019899754377166	[15,13]	[13,13]	-3	hSpCas9	positive selection	3120305
78155230	78155253		+	24336571	A375	resistance to PLX after 7 days	GGCATTCCACAACCCAAAACAGG	IDH3A	ENSG00000166411	-0.14718799636062352	[3,7]	[3,5]	-5	hSpCas9	positive selection	3120307
78165017	78165040		+	24336571	A375	resistance to PLX after 7 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	0.07057220820933452	[1,2]	[2,2]	2	hSpCas9	positive selection	3120308
78164984	78165007		+	24336571	A375	resistance to PLX after 7 days	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	-0.1017048676316108	[22,19]	[19,18]	-3	hSpCas9	positive selection	3120309
78155206	78155229		+	24336571	A375	resistance to PLX after 14 days	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.5979955632429215	[17,13]	[4,3]	-7	hSpCas9	positive selection	3178098
78155230	78155253		+	24336571	A375	resistance to PLX after 14 days	GGCATTCCACAACCCAAAACAGG	IDH3A	ENSG00000166411	-0.1495902968908438	[5,7]	[2,1]	-1	hSpCas9	positive selection	3178100
78165017	78165040		+	24336571	A375	resistance to PLX after 14 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	1.1137760863534263	[1,1]	[1,1]	8	hSpCas9	positive selection	3178101
78164984	78165007		+	24336571	A375	resistance to PLX after 14 days	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	-0.28839018197121347	[17,12]	[5,5]	-3	hSpCas9	positive selection	3178102
78155206	78155229		+	24336571	A375	viability after 7 days	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	0.08558507346555816	[14]	[15,13]	1	hSpCas9	negative selection	3235891
78155230	78155253		+	24336571	A375	viability after 7 days	GGCATTCCACAACCCAAAACAGG	IDH3A	ENSG00000166411	-1.0320863329225423	[12]	[3,7]	-9	hSpCas9	negative selection	3235893
78165017	78165040		+	24336571	A375	viability after 7 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.5418945205489012	[4]	[1,2]	-6	hSpCas9	negative selection	3235894
78164984	78165007		+	24336571	A375	viability after 7 days	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.24680754860547116	[18]	[22,19]	4	hSpCas9	negative selection	3235895
78155206	78155229		+	24336571	A375	viability after 14 days	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	0.1394430844593959	[14]	[17,13]	1	hSpCas9	negative selection	3293684
78155230	78155253		+	24336571	A375	viability after 14 days	GGCATTCCACAACCCAAAACAGG	IDH3A	ENSG00000166411	-0.8197889595120128	[12]	[5,7]	-7	hSpCas9	negative selection	3293686
78165017	78165040		+	24336571	A375	viability after 14 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.9841948030839622	[4]	[1,1]	-8	hSpCas9	negative selection	3293687
78164984	78165007		+	24336571	A375	viability after 14 days	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	-0.1417090906145947	[18]	[17,12]	-2	hSpCas9	negative selection	3293688
78160084	78160107	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.42215388805961096	[204,204]	[0,0]	-3	hSpCas9	positive selection	3373685
78160145	78160168	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	1.4759664979211755	[54,54]	[0,0]	6	hSpCas9	positive selection	3373686
78157551	78157574	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.35000410230377543	[194,194]	[0,0]	-2	hSpCas9	positive selection	3373687
78161612	78161635	15	-	26780180	HT29	viability (Avana library 4 designs)	GCAGCAGTAAATTCATAGATGGG	IDH3A	ENSG00000166411	1.95554378514437	[]	[]	7	hSpCas9	negative selection	3432058
78149414	78149437	15	-	26780180	HT29	viability (Avana library 4 designs)	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	1.18643025392468	[]	[]	4	hSpCas9	negative selection	3432059
78157557	78157580	15	+	26780180	HT29	viability (Avana library 4 designs)	GTAACTTTAATTCCAGGAGATGG	IDH3A	ENSG00000166411	2.63888611324084	[]	[]	8	hSpCas9	negative selection	3432060
78162256	78162279	15	+	26780180	HT29	viability (Avana library 4 designs)	GTATCAAGCTCATCACCGAGGGG	IDH3A	ENSG00000166411	3.0625211010144	[]	[]	8	hSpCas9	negative selection	3432061
78149414	78149437	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-7.82864281858657	[]	[]	-7	hSpCas9	negative selection	3518021
78162256	78162279	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTATCAAGCTCATCACCGAGGGG	IDH3A	ENSG00000166411	-13.2992921341129	[]	[]	-8	hSpCas9	negative selection	3518022
78161612	78161635	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCAGTAAATTCATAGATGGG	IDH3A	ENSG00000166411	-0.795875705898077	[]	[]	-1	hSpCas9	negative selection	3518023
78157557	78157580	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAACTTTAATTCCAGGAGATGG	IDH3A	ENSG00000166411	-16.7423264104707	[]	[]	-9	hSpCas9	negative selection	3518024
78160157	78160180	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGGACTCTTTAGCCTCTGAAGGG	IDH3A	ENSG00000166411	-0.664876183732321	[]	[]	-1	hSpCas9	negative selection	3518025
78149413	78149436	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTCACCTTAGAGATCCACGCGGG	IDH3A	ENSG00000166411	-3.62119884311492	[]	[]	-4	hSpCas9	negative selection	3518026
78149414	78149437	15	-	26780180	A375	viability (Avana lentiGuide)	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	26.4393858838379	[]	[]	9	hSpCas9	negative selection	3626680
78162256	78162279	15	+	26780180	A375	viability (Avana lentiGuide)	GTATCAAGCTCATCACCGAGGGG	IDH3A	ENSG00000166411	28.4947574607906	[]	[]	9	hSpCas9	negative selection	3626681
78161612	78161635	15	-	26780180	A375	viability (Avana lentiGuide)	GCAGCAGTAAATTCATAGATGGG	IDH3A	ENSG00000166411	6.78756278005571	[]	[]	5	hSpCas9	negative selection	3626682
78157557	78157580	15	+	26780180	A375	viability (Avana lentiGuide)	GTAACTTTAATTCCAGGAGATGG	IDH3A	ENSG00000166411	19.4153251592036	[]	[]	8	hSpCas9	negative selection	3626683
78160157	78160180	15	-	26780180	A375	viability (Avana lentiGuide)	TGGACTCTTTAGCCTCTGAAGGG	IDH3A	ENSG00000166411	3.07995453351202	[]	[]	3	hSpCas9	negative selection	3626684
78149413	78149436	15	-	26780180	A375	viability (Avana lentiGuide)	CTCACCTTAGAGATCCACGCGGG	IDH3A	ENSG00000166411	8.90950161770607	[]	[]	6	hSpCas9	negative selection	3626685
78149414	78149437	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-0.40821051938566344	[4]	[3,3]	-6	hSpCas9	positive selection	3735339
78162256	78162279	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTATCAAGCTCATCACCGAGGGG	IDH3A	ENSG00000166411	-0.4429257496641069	[4]	[2,2]	-6	hSpCas9	positive selection	3735340
78161612	78161635	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCAGTAAATTCATAGATGGG	IDH3A	ENSG00000166411	0.004561356621909707	[6]	[6,6]	0	hSpCas9	positive selection	3735341
78157557	78157580	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAACTTTAATTCCAGGAGATGG	IDH3A	ENSG00000166411	-1.552233087304152	[5]	[1,0]	-9	hSpCas9	positive selection	3735342
78160157	78160180	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGACTCTTTAGCCTCTGAAGGG	IDH3A	ENSG00000166411	0.08047752896628327	[5]	[6,5]	2	hSpCas9	positive selection	3735343
78149413	78149436	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCACCTTAGAGATCCACGCGGG	IDH3A	ENSG00000166411	-0.6711485568763534	[4]	[3,1]	-7	hSpCas9	positive selection	3735344
78149414	78149437	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-0.7356091504498344	[5]	[1,2]	-7	hSpCas9	positive selection	3843946
78162256	78162279	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTATCAAGCTCATCACCGAGGGG	IDH3A	ENSG00000166411	-1.8946700508454992	[4]	[0,0]	-9	hSpCas9	positive selection	3843947
78161612	78161635	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCAGTAAATTCATAGATGGG	IDH3A	ENSG00000166411	0.1896615631041902	[6]	[6,5]	4	hSpCas9	positive selection	3843948
78157557	78157580	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAACTTTAATTCCAGGAGATGG	IDH3A	ENSG00000166411	-0.02283561670528346	[4]	[4,3]	0	hSpCas9	positive selection	3843949
78160157	78160180	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGACTCTTTAGCCTCTGAAGGG	IDH3A	ENSG00000166411	-0.02462270873572449	[5]	[5,2]	0	hSpCas9	positive selection	3843950
78149413	78149436	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCACCTTAGAGATCCACGCGGG	IDH3A	ENSG00000166411	-0.36879139808717587	[5]	[3,2]	-5	hSpCas9	positive selection	3843951
78160145	78160168	15	+	26780180	A375	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	1.88979371516307	[]	[]	9	hSpCas9	negative selection	3949928
78155206	78155229	15	+	26780180	A375	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	0.54331426351483	[]	[]	1	hSpCas9	negative selection	3949929
78157551	78157574	15	+	26780180	A375	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	2.48822430266727	[]	[]	9	hSpCas9	negative selection	3949930
78160084	78160107	15	+	26780180	A375	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	1.75063272354241	[]	[]	9	hSpCas9	negative selection	3949931
78165017	78165040	15	+	26780180	A375	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	1.28015003199514	[]	[]	7	hSpCas9	negative selection	3949932
78164984	78165007	15	+	26780180	A375	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	2.486124075834	[]	[]	9	hSpCas9	negative selection	3949933
78160145	78160168	15	+	26780180	HT29	viability (GeCKOv2 library)	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	2.06701021631084	[]	[]	9	hSpCas9	negative selection	4057894
78155206	78155229	15	+	26780180	HT29	viability (GeCKOv2 library)	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	1.69639135088679	[]	[]	8	hSpCas9	negative selection	4057895
78157551	78157574	15	+	26780180	HT29	viability (GeCKOv2 library)	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	1.78284768130696	[]	[]	8	hSpCas9	negative selection	4057896
78160084	78160107	15	+	26780180	HT29	viability (GeCKOv2 library)	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	1.73427669351248	[]	[]	8	hSpCas9	negative selection	4057897
78165017	78165040	15	+	26780180	HT29	viability (GeCKOv2 library)	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	1.11837954262194	[]	[]	5	hSpCas9	negative selection	4057898
78164984	78165007	15	+	26780180	HT29	viability (GeCKOv2 library)	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	2.40062898702749	[]	[]	9	hSpCas9	negative selection	4057899
78155206	78155229	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.30933430067528744	[4]	[1,1]	-6	hSpCas9	positive selection	4143890
78155230	78155253	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCATTCCACAACCCAAAACAGG	IDH3A	ENSG00000166411	0.007726818115421974	[2]	[1,1]	0	hSpCas9	positive selection	4143892
78165017	78165040	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.672911996905226	[2]	[0,0]	-9	hSpCas9	positive selection	4143893
78164984	78165007	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	-0.14510081360956043	[4]	[2,2]	-3	hSpCas9	positive selection	4143894
78155206	78155229	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.332418883547236	[4]	[0,2,2,0]	-5	hSpCas9	positive selection	4207912
78155230	78155253	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCATTCCACAACCCAAAACAGG	IDH3A	ENSG00000166411	0.46289153388680226	[2]	[0,2,4,0]	3	hSpCas9	positive selection	4207914
78165017	78165040	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	0.9751653931942506	[2]	[0,0,0,3]	6	hSpCas9	positive selection	4207915
78164984	78165007	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	-0.6642611753420795	[3]	[1,0,0,0]	-8	hSpCas9	positive selection	4207916
78165017	78165040	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	0.20733576748209365	[1]	[1,1]	4	hSpCas9	positive selection	4276224
78164984	78165007	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	-0.23732896065080022	[4]	[2,2]	-5	hSpCas9	positive selection	4276225
78155206	78155229	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.15869930767298188	[3]	[3,1]	-3	hSpCas9	positive selection	4276226
78160084	78160107	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	0.3143782557382506	[3]	[3,3]	6	hSpCas9	positive selection	4340482
78160145	78160168	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.1643982720064238	[2]	[1,1]	-3	hSpCas9	positive selection	4340483
78157551	78157574	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	0.02599539108487775	[3]	[2,2]	0	hSpCas9	positive selection	4340484
78161648	78161670	15	-	27760321	OCIAML3	viability	TGGTCGGACATTCGCGTAAAGG	IDH3A	ENSG00000166411	0.8017222229511919	[490,406]	[529,712]	8	hSpCas9	negative selection	4408693
78161667	78161689	15	-	27760321	OCIAML3	viability	AGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-1.0558763403007283	[144,130]	[50,52]	-7	hSpCas9	negative selection	4408694
78161695	78161717	15	-	27760321	OCIAML3	viability	ATATTTACATCGGTGTAAGGGG	IDH3A	ENSG00000166411	-2.858874318125526	[5,11]	[0,0]	-9	hSpCas9	negative selection	4408695
78161722	78161744	15	-	27760321	OCIAML3	viability	CCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	0.1580380272009263	[578,500]	[314,671]	1	hSpCas9	negative selection	4408696
78162256	78162278	15	+	27760321	OCIAML3	viability	GTATCAAGCTCATCACCGAGGG	IDH3A	ENSG00000166411	-0.18162668242128885	[519,480]	[253,463]	-2	hSpCas9	negative selection	4408697
78161648	78161670	15	-	27760321	OCIAML2	viability	TGGTCGGACATTCGCGTAAAGG	IDH3A	ENSG00000166411	0.5407038136267536	[490,406]	[434,645]	7	hSpCas9	negative selection	4492156
78161667	78161689	15	-	27760321	OCIAML2	viability	AGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-0.10962024972266593	[144,130]	[89,120]	-1	hSpCas9	negative selection	4492157
78161695	78161717	15	-	27760321	OCIAML2	viability	ATATTTACATCGGTGTAAGGGG	IDH3A	ENSG00000166411	0.059839788535489546	[5,11]	[12,0]	0	hSpCas9	negative selection	4492158
78161722	78161744	15	-	27760321	OCIAML2	viability	CCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	0.11496954622021505	[578,500]	[413,547]	1	hSpCas9	negative selection	4492159
78162256	78162278	15	+	27760321	OCIAML2	viability	GTATCAAGCTCATCACCGAGGG	IDH3A	ENSG00000166411	-0.13900750754016322	[519,480]	[365,369]	-2	hSpCas9	negative selection	4492160
78161648	78161670	15	-	27760321	MV411	viability	TGGTCGGACATTCGCGTAAAGG	IDH3A	ENSG00000166411	0.5972723784161096	[490,406]	[544,297]	4	hSpCas9	negative selection	4575619
78161667	78161689	15	-	27760321	MV411	viability	AGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	2.2191307243164866	[144,130]	[234,706]	9	hSpCas9	negative selection	4575620
78161695	78161717	15	-	27760321	MV411	viability	ATATTTACATCGGTGTAAGGGG	IDH3A	ENSG00000166411	-2.613795749210844	[5,11]	[0,0]	-9	hSpCas9	negative selection	4575621
78161722	78161744	15	-	27760321	MV411	viability	CCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-0.03553194624248546	[578,500]	[295,422]	0	hSpCas9	negative selection	4575622
78162256	78162278	15	+	27760321	MV411	viability	GTATCAAGCTCATCACCGAGGG	IDH3A	ENSG00000166411	0.6932260329544867	[519,480]	[623,398]	5	hSpCas9	negative selection	4575623
78161648	78161670	15	-	27760321	HL60	viability	TGGTCGGACATTCGCGTAAAGG	IDH3A	ENSG00000166411	0.48743737863343434	[490,406]	[360,671]	6	hSpCas9	negative selection	4659082
78161667	78161689	15	-	27760321	HL60	viability	AGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	0.6262825812104122	[144,130]	[52,301]	7	hSpCas9	negative selection	4659083
78161695	78161717	15	-	27760321	HL60	viability	ATATTTACATCGGTGTAAGGGG	IDH3A	ENSG00000166411	-1.144813077344721	[5,11]	[0,5]	-8	hSpCas9	negative selection	4659084
78161722	78161744	15	-	27760321	HL60	viability	CCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	0.20138902367324263	[578,500]	[500,510]	2	hSpCas9	negative selection	4659085
78162256	78162278	15	+	27760321	HL60	viability	GTATCAAGCTCATCACCGAGGG	IDH3A	ENSG00000166411	0.7173864537063472	[519,480]	[747,591]	7	hSpCas9	negative selection	4659086
78161648	78161670	15	-	27760321	HT1080	viability	TGGTCGGACATTCGCGTAAAGG	IDH3A	ENSG00000166411	-7.1741188465232995	[406,317]	[0,0]	-9	hSpCas9	negative selection	4742545
78161667	78161689	15	-	27760321	HT1080	viability	AGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-5.536158612530349	[130,101]	[0,0]	-8	hSpCas9	negative selection	4742546
78161695	78161717	15	-	27760321	HT1080	viability	ATATTTACATCGGTGTAAGGGG	IDH3A	ENSG00000166411	-2.137477237836361	[11,9]	[0,0]	-6	hSpCas9	negative selection	4742547
78161722	78161744	15	-	27760321	HT1080	viability	CCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-6.910066524176837	[500,390]	[0,1]	-9	hSpCas9	negative selection	4742548
78162256	78162278	15	+	27760321	HT1080	viability	GTATCAAGCTCATCACCGAGGG	IDH3A	ENSG00000166411	-7.415476249590625	[480,375]	[0,0]	-9	hSpCas9	negative selection	4742549
78161648	78161670	15	-	27760321	HT29	viability after 7 days	TGGTCGGACATTCGCGTAAAGG	IDH3A	ENSG00000166411	-0.17540731000031656	[406,317]	[433,372,432]	-3	hSpCas9	negative selection	4826008
78161667	78161689	15	-	27760321	HT29	viability after 7 days	AGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	0.16833216128063455	[130,101]	[339,111,79]	2	hSpCas9	negative selection	4826009
78161695	78161717	15	-	27760321	HT29	viability after 7 days	ATATTTACATCGGTGTAAGGGG	IDH3A	ENSG00000166411	-2.0522013805074923	[11,9]	[0,7,0]	-9	hSpCas9	negative selection	4826010
78161722	78161744	15	-	27760321	HT29	viability after 7 days	CCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-0.04766928096291084	[500,390]	[328,417,873]	0	hSpCas9	negative selection	4826011
78162256	78162278	15	+	27760321	HT29	viability after 7 days	GTATCAAGCTCATCACCGAGGG	IDH3A	ENSG00000166411	-0.4572936200419727	[480,375]	[519,512,193]	-6	hSpCas9	negative selection	4826012
78161648	78161670	15	-	27760321	HT29	viability after 25 days	TGGTCGGACATTCGCGTAAAGG	IDH3A	ENSG00000166411	-1.1891962654969026	[406,317]	[76,252,225]	-7	hSpCas9	negative selection	4909471
78161667	78161689	15	-	27760321	HT29	viability after 25 days	AGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-1.6678882200340543	[130,101]	[48,52,20]	-7	hSpCas9	negative selection	4909472
78161695	78161717	15	-	27760321	HT29	viability after 25 days	ATATTTACATCGGTGTAAGGGG	IDH3A	ENSG00000166411	-0.8327753339960973	[11,9]	[0,18,0]	-6	hSpCas9	negative selection	4909473
78161722	78161744	15	-	27760321	HT29	viability after 25 days	CCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-1.9713744622380405	[500,390]	[95,138,159]	-8	hSpCas9	negative selection	4909474
78162256	78162278	15	+	27760321	HT29	viability after 25 days	GTATCAAGCTCATCACCGAGGG	IDH3A	ENSG00000166411	-1.7412246033053769	[480,375]	[145,131,162]	-7	hSpCas9	negative selection	4909475
78161648	78161670	15	-	27760321	HT29	viability after 22 days	TGGTCGGACATTCGCGTAAAGG	IDH3A	ENSG00000166411	-0.9415216890253679	[406,317]	[432,84,129]	-6	hSpCas9	negative selection	4992934
78161667	78161689	15	-	27760321	HT29	viability after 22 days	AGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-0.9000518329623242	[130,101]	[87,60,66]	-6	hSpCas9	negative selection	4992935
78161695	78161717	15	-	27760321	HT29	viability after 22 days	ATATTTACATCGGTGTAAGGGG	IDH3A	ENSG00000166411	-0.17964775930701737	[11,9]	[0,31,0]	-2	hSpCas9	negative selection	4992936
78161722	78161744	15	-	27760321	HT29	viability after 22 days	CCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-2.0569819453729035	[500,390]	[76,65,230]	-8	hSpCas9	negative selection	4992937
78162256	78162278	15	+	27760321	HT29	viability after 22 days	GTATCAAGCTCATCACCGAGGG	IDH3A	ENSG00000166411	-1.2992425712985822	[480,375]	[305,206,86]	-7	hSpCas9	negative selection	4992938
78161648	78161670	15	-	27760321	HT29	viability after 19 days	TGGTCGGACATTCGCGTAAAGG	IDH3A	ENSG00000166411	-0.7843610506291507	[406,317]	[245,166,306]	-6	hSpCas9	negative selection	5076397
78161667	78161689	15	-	27760321	HT29	viability after 19 days	AGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-0.8956506603261734	[130,101]	[74,91,48]	-6	hSpCas9	negative selection	5076398
78161695	78161717	15	-	27760321	HT29	viability after 19 days	ATATTTACATCGGTGTAAGGGG	IDH3A	ENSG00000166411	-3.658638082118931	[11,9]	[0,0,0]	-9	hSpCas9	negative selection	5076399
78161722	78161744	15	-	27760321	HT29	viability after 19 days	CCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-1.7266276684719644	[500,390]	[180,100,181]	-7	hSpCas9	negative selection	5076400
78162256	78162278	15	+	27760321	HT29	viability after 19 days	GTATCAAGCTCATCACCGAGGG	IDH3A	ENSG00000166411	-1.664074709270371	[480,375]	[205,155,108]	-7	hSpCas9	negative selection	5076401
78161648	78161670	15	-	27760321	HT29	viability after 16 days	TGGTCGGACATTCGCGTAAAGG	IDH3A	ENSG00000166411	-0.8844666421717232	[406,317]	[291,177,196]	-6	hSpCas9	negative selection	5159860
78161667	78161689	15	-	27760321	HT29	viability after 16 days	AGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-0.023009696634702426	[130,101]	[123,26,235]	0	hSpCas9	negative selection	5159861
78161695	78161717	15	-	27760321	HT29	viability after 16 days	ATATTTACATCGGTGTAAGGGG	IDH3A	ENSG00000166411	-2.9331729258673453	[11,9]	[2,0,0]	-9	hSpCas9	negative selection	5159862
78161722	78161744	15	-	27760321	HT29	viability after 16 days	CCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-0.46869730209921845	[500,390]	[391,384,306]	-5	hSpCas9	negative selection	5159863
78162256	78162278	15	+	27760321	HT29	viability after 16 days	GTATCAAGCTCATCACCGAGGG	IDH3A	ENSG00000166411	-0.9695563764681683	[480,375]	[314,248,176]	-7	hSpCas9	negative selection	5159864
78161648	78161670	15	-	27760321	HT29	viability after 13 days	TGGTCGGACATTCGCGTAAAGG	IDH3A	ENSG00000166411	-0.37928532976941726	[406,317]	[467,269,236]	-4	hSpCas9	negative selection	5243323
78161667	78161689	15	-	27760321	HT29	viability after 13 days	AGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-0.9547966840501039	[130,101]	[39,112,56]	-7	hSpCas9	negative selection	5243324
78161695	78161717	15	-	27760321	HT29	viability after 13 days	ATATTTACATCGGTGTAAGGGG	IDH3A	ENSG00000166411	-3.6794610291421472	[11,9]	[0,0,0]	-9	hSpCas9	negative selection	5243325
78161722	78161744	15	-	27760321	HT29	viability after 13 days	CCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-1.0559967664553291	[500,390]	[252,218,272]	-7	hSpCas9	negative selection	5243326
78162256	78162278	15	+	27760321	HT29	viability after 13 days	GTATCAAGCTCATCACCGAGGG	IDH3A	ENSG00000166411	-0.685374206363986	[480,375]	[220,335,366]	-6	hSpCas9	negative selection	5243327
78161648	78161670	15	-	27760321	HT29	viability after 10 days	TGGTCGGACATTCGCGTAAAGG	IDH3A	ENSG00000166411	0.17016158032266243	[406,317]	[446,460,615]	2	hSpCas9	negative selection	5326786
78161667	78161689	15	-	27760321	HT29	viability after 10 days	AGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-0.8650346099569222	[130,101]	[86,85,66]	-7	hSpCas9	negative selection	5326787
78161695	78161717	15	-	27760321	HT29	viability after 10 days	ATATTTACATCGGTGTAAGGGG	IDH3A	ENSG00000166411	-3.785472336302491	[11,9]	[0,0,0]	-9	hSpCas9	negative selection	5326788
78161722	78161744	15	-	27760321	HT29	viability after 10 days	CCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-0.18456977745882183	[500,390]	[533,492,443]	-2	hSpCas9	negative selection	5326789
78162256	78162278	15	+	27760321	HT29	viability after 10 days	GTATCAAGCTCATCACCGAGGG	IDH3A	ENSG00000166411	-0.4568610035618511	[480,375]	[305,438,424]	-5	hSpCas9	negative selection	5326790
78161648	78161670	15	-	27760321	MOLM13	viability	TGGTCGGACATTCGCGTAAAGG	IDH3A	ENSG00000166411	2.1572372153153094	[490,406]	[1366,918]	9	hSpCas9	negative selection	5410249
78161667	78161689	15	-	27760321	MOLM13	viability	AGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	1.3485102842135448	[144,130]	[21,347]	8	hSpCas9	negative selection	5410250
78161695	78161717	15	-	27760321	MOLM13	viability	ATATTTACATCGGTGTAAGGGG	IDH3A	ENSG00000166411	-2.387738936383249	[5,11]	[0,0]	-8	hSpCas9	negative selection	5410251
78161722	78161744	15	-	27760321	MOLM13	viability	CCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	0.36351288444430063	[578,500]	[485,309]	2	hSpCas9	negative selection	5410252
78162256	78162278	15	+	27760321	MOLM13	viability	GTATCAAGCTCATCACCGAGGG	IDH3A	ENSG00000166411	1.2199812288961263	[519,480]	[585,718]	8	hSpCas9	negative selection	5410253
78131584	78131607	15	+	27661255	K562	viability	GGGACAAAGACCCGGAGCGGCGG	IDH3A	ENSG00000166411	-0.017595415107744983	[410,528]	[406,336]	0	dCas9-KRAB	negative selection	5486057
78131724	78131747	15	+	27661255	K562	viability	GAGTGGCGCCCCTTGACCTGGGG	IDH3A	ENSG00000166411	0.14975223305653929	[1981,1976]	[1919,1612]	5	dCas9-KRAB	negative selection	5486058
78149330	78149353	15	+	27661255	K562	viability	GCGGGCTCCGAGCGTGGGGTGGG	IDH3A	ENSG00000166411	-0.8412184548605399	[562,566]	[239,261]	-8	dCas9-KRAB	negative selection	5486059
78149374	78149397	15	+	27661255	K562	viability	GCTGTTGCTGCGGAGCCAGGAGG	IDH3A	ENSG00000166411	-1.7886469814897517	[563,619]	[127,143]	-9	dCas9-KRAB	negative selection	5486060
78149597	78149620	15	+	27661255	K562	viability	GTGGCCGGCTCGCAGTGTATGGG	IDH3A	ENSG00000166411	-0.292110178359706	[249,251]	[207,125]	-7	dCas9-KRAB	negative selection	5486061
78149745	78149768	15	+	27661255	K562	viability	GCTTCGCGCCGAGCCCGGGAAGG	IDH3A	ENSG00000166411	-0.16863046104656454	[326,394]	[286,228]	-5	dCas9-KRAB	negative selection	5486062
78131520	78131543	15	-	27661255	K562	viability	GGGAGCCAAGGGTTCGTGCCGGG	IDH3A	ENSG00000166411	0.19090228929398687	[657,626]	[574,595]	6	dCas9-KRAB	negative selection	5486063
78131831	78131854	15	-	27661255	K562	viability	GAGGGACAGGGCCCGGGTAAGGG	IDH3A	ENSG00000166411	-1.1845036417768524	[834,760]	[335,233]	-8	dCas9-KRAB	negative selection	5486064
78131917	78131940	15	-	27661255	K562	viability	GCCGCGCCCAAAGGCCAGATGGG	IDH3A	ENSG00000166411	0.05462031353647523	[509,502]	[449,394]	1	dCas9-KRAB	negative selection	5486065
78149866	78149889	15	-	27661255	K562	viability	GCCAAGGGCCGCGCAGACAGCGG	IDH3A	ENSG00000166411	0.033808844139660565	[361,500]	[393,313]	1	dCas9-KRAB	negative selection	5486066
78165017	78165040	15	+	27260156	BXPC3	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.14334332451625875	[166]	[145,147,169,170]	-3	hSpCas9	negative selection	5548684
78164984	78165007	15	+	27260156	BXPC3	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.20680355287311492	[1067]	[1244,1269,1405,1224]	4	hSpCas9	negative selection	5548685
78155206	78155229	15	+	27260156	BXPC3	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.15421134830945327	[552]	[451,591,452,587]	-4	hSpCas9	negative selection	5548686
78160084	78160107	15	+	27260156	BXPC3	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.5741466278312863	[719]	[473,528,513,503]	-8	hSpCas9	negative selection	5612942
78160145	78160168	15	+	27260156	BXPC3	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.33942132311962314	[283]	[197,198,202,357]	-6	hSpCas9	negative selection	5612943
78157551	78157574	15	+	27260156	BXPC3	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.303216674790899	[680]	[531,548,547,695]	-6	hSpCas9	negative selection	5612944
78165017	78165040	15	+	27260156	A673	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.2365260598649932	[166]	[231,169,160,121]	-5	hSpCas9	negative selection	5669935
78164984	78165007	15	+	27260156	A673	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.20708127804913046	[1067]	[1790,1266,1454,1444]	5	hSpCas9	negative selection	5669936
78155206	78155229	15	+	27260156	A673	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.526722724239269	[552]	[526,383,467,473]	-8	hSpCas9	negative selection	5669937
78160084	78160107	15	+	27260156	A673	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.023483272926970833	[719]	[991,880,715,826]	0	hSpCas9	negative selection	5734193
78160145	78160168	15	+	27260156	A673	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.39506125215553156	[283]	[285,232,254,266]	-7	hSpCas9	negative selection	5734194
78157551	78157574	15	+	27260156	A673	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.24063827240797625	[680]	[706,640,621,806]	-5	hSpCas9	negative selection	5734195
78165017	78165040	15	+	27260156	A375	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-3.3591576445970794	[166]	[14,0,15,38]	-9	hSpCas9	negative selection	5791186
78164984	78165007	15	+	27260156	A375	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	-0.2551752996721439	[1067]	[973,1270,1170,818]	-4	hSpCas9	negative selection	5791187
78155206	78155229	15	+	27260156	A375	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.6039826522865561	[552]	[408,595,394,332]	-7	hSpCas9	negative selection	5791188
78160084	78160107	15	+	27260156	A375	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-1.80029551646279	[719]	[325,143,351,141]	-9	hSpCas9	negative selection	5855444
78160145	78160168	15	+	27260156	A375	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-1.1207620407467447	[283]	[157,181,160,116]	-8	hSpCas9	negative selection	5855445
78157551	78157574	15	+	27260156	A375	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-1.325138681944193	[680]	[384,228,308,331]	-9	hSpCas9	negative selection	5855446
78165017	78165040	15	+	27260156	COLO741	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.621086936350582	[166]	[148,62,199]	-8	hSpCas9	negative selection	5912437
78164984	78165007	15	+	27260156	COLO741	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.02292009567248443	[1067]	[1604,1345,1234]	0	hSpCas9	negative selection	5912438
78155206	78155229	15	+	27260156	COLO741	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.3424387141915561	[552]	[501,522,634]	-6	hSpCas9	negative selection	5912439
78160084	78160107	15	+	27260156	COLO741	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.643909896908842	[719]	[608,490,660]	-8	hSpCas9	negative selection	5976695
78160145	78160168	15	+	27260156	COLO741	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.9934985670772362	[283]	[224,185,141]	-9	hSpCas9	negative selection	5976696
78157551	78157574	15	+	27260156	COLO741	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.4344518809024145	[680]	[776,531,632]	-7	hSpCas9	negative selection	5976697
78165017	78165040	15	+	27260156	CAL120	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.1923024732778784	[166]	[103,93,76]	-9	hSpCas9	negative selection	6033688
78164984	78165007	15	+	27260156	CAL120	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.1244935975297905	[1067]	[1809,1247,1343]	1	hSpCas9	negative selection	6033689
78155206	78155229	15	+	27260156	CAL120	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.2733895391807196	[552]	[518,597,582]	-4	hSpCas9	negative selection	6033690
78160084	78160107	15	+	27260156	CAL120	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-1.4087092544244086	[719]	[300,269,433]	-9	hSpCas9	negative selection	6097946
78160145	78160168	15	+	27260156	CAL120	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-1.2987222208047164	[283]	[139,70,217]	-9	hSpCas9	negative selection	6097947
78157551	78157574	15	+	27260156	CAL120	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.18885873045237161	[680]	[928,699,630]	-3	hSpCas9	negative selection	6097948
78165017	78165040	15	+	27260156	CADOES1	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.14896013078299508	[166]	[136,115,97,211]	-3	hSpCas9	negative selection	6154939
78164984	78165007	15	+	27260156	CADOES1	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.1618325676174237	[1067]	[1047,1236,1081,1076]	2	hSpCas9	negative selection	6154940
78155206	78155229	15	+	27260156	CADOES1	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.24267400824995272	[552]	[397,358,487,495]	-4	hSpCas9	negative selection	6154941
78160084	78160107	15	+	27260156	CADOES1	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.5380301695731787	[719]	[399,481,423,541]	-7	hSpCas9	negative selection	6219197
78160145	78160168	15	+	27260156	CADOES1	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.8266313614748603	[283]	[233,96,74,190]	-8	hSpCas9	negative selection	6219198
78157551	78157574	15	+	27260156	CADOES1	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.19810448666287472	[680]	[532,655,510,506]	-3	hSpCas9	negative selection	6219199
78165017	78165040	15	+	27260156	EWS502	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	0.16662424413943744	[166]	[247,127,239,172]	3	hSpCas9	negative selection	6276190
78164984	78165007	15	+	27260156	EWS502	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.192478974918602	[1067]	[958,1352,1264,1651]	3	hSpCas9	negative selection	6276191
78155206	78155229	15	+	27260156	EWS502	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.36360839634266773	[552]	[400,462,380,588]	-6	hSpCas9	negative selection	6276192
78160084	78160107	15	+	27260156	EWS502	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.009232860279217991	[719]	[644,936,701,748]	0	hSpCas9	negative selection	6340448
78160145	78160168	15	+	27260156	EWS502	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.6368928271772648	[283]	[202,137,236,196]	-7	hSpCas9	negative selection	6340449
78157551	78157574	15	+	27260156	EWS502	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.24259640076676625	[680]	[678,599,606,536]	-4	hSpCas9	negative selection	6340450
78165017	78165040	15	+	27260156	EW8	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.32548518532095394	[166]	[178,57,61,147]	-6	hSpCas9	negative selection	6397441
78164984	78165007	15	+	27260156	EW8	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.22843003456553723	[1067]	[1200,966,814,1123]	4	hSpCas9	negative selection	6397442
78155206	78155229	15	+	27260156	EW8	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.46507685146996913	[552]	[333,277,338,344]	-7	hSpCas9	negative selection	6397443
78160084	78160107	15	+	27260156	EW8	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.21996192601502218	[719]	[604,515,400,508]	-4	hSpCas9	negative selection	6461699
78160145	78160168	15	+	27260156	EW8	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.22674978519647038	[283]	[251,215,163,165]	-4	hSpCas9	negative selection	6461700
78157551	78157574	15	+	27260156	EW8	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.31132669728576984	[680]	[581,370,424,417]	-5	hSpCas9	negative selection	6461701
78165017	78165040	15	+	27260156	CORL105	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.5705070061894335	[166]	[172,94,145,116]	-8	hSpCas9	negative selection	6518692
78164984	78165007	15	+	27260156	CORL105	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.28992484919527306	[1067]	[1590,1368,1705,1480]	5	hSpCas9	negative selection	6518693
78155206	78155229	15	+	27260156	CORL105	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.3901129178171677	[552]	[451,530,439,541]	-6	hSpCas9	negative selection	6518694
78160084	78160107	15	+	27260156	CORL105	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.5580209617961737	[719]	[714,501,600,482]	-7	hSpCas9	negative selection	6582950
78160145	78160168	15	+	27260156	CORL105	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.9224521646304472	[283]	[218,196,156,126]	-9	hSpCas9	negative selection	6582951
78157551	78157574	15	+	27260156	CORL105	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.3757367870677989	[680]	[585,619,730,537]	-6	hSpCas9	negative selection	6582952
78165017	78165040	15	+	27260156	HS294T	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.3015311439780419	[166]	[58,18,68,64]	-4	hSpCas9	negative selection	6639943
78164984	78165007	15	+	27260156	HS294T	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.15027128370610976	[1067]	[355,486,411,610]	2	hSpCas9	negative selection	6639944
78155206	78155229	15	+	27260156	HS294T	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	0.21519899967742753	[552]	[331,232,157,263]	3	hSpCas9	negative selection	6639945
78160084	78160107	15	+	27260156	HS294T	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.6269731529480647	[719]	[141,111,279,194]	-7	hSpCas9	negative selection	6704201
78160145	78160168	15	+	27260156	HS294T	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-1.259337920830741	[283]	[38,31,49,66]	-9	hSpCas9	negative selection	6704202
78157551	78157574	15	+	27260156	HS294T	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.5075318957124697	[680]	[180,154,148,270]	-6	hSpCas9	negative selection	6704203
78165017	78165040	15	+	27260156	HCC44	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.9466194378171298	[166]	[114,39,85,155]	-8	hSpCas9	negative selection	6761194
78164984	78165007	15	+	27260156	HCC44	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.1006340808111319	[1067]	[1789,940,1437,1126]	1	hSpCas9	negative selection	6761195
78155206	78155229	15	+	27260156	HCC44	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.09141254157328874	[552]	[576,657,477,599]	-1	hSpCas9	negative selection	6761196
78160084	78160107	15	+	27260156	HCC44	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-1.178149834310183	[719]	[328,342,421,352]	-9	hSpCas9	negative selection	6825452
78160145	78160168	15	+	27260156	HCC44	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-1.043511476780294	[283]	[159,134,171,160]	-8	hSpCas9	negative selection	6825453
78157551	78157574	15	+	27260156	HCC44	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.33290872853794784	[680]	[872,464,710,458]	-5	hSpCas9	negative selection	6825454
78165017	78165040	15	+	27260156	G402	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.3274584229566293	[166]	[60,43,145,68]	-9	hSpCas9	negative selection	6882445
78164984	78165007	15	+	27260156	G402	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.23784196994181706	[1067]	[1697,1170,1736,1536]	3	hSpCas9	negative selection	6882446
78155206	78155229	15	+	27260156	G402	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.6112694499807142	[552]	[388,282,648,427]	-6	hSpCas9	negative selection	6882447
78160084	78160107	15	+	27260156	G402	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-1.9454083027656328	[719]	[86,191,422,188]	-9	hSpCas9	negative selection	6946703
78160145	78160168	15	+	27260156	G402	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.31081793609326314	[283]	[460,75,275,315]	-4	hSpCas9	negative selection	6946704
78157551	78157574	15	+	27260156	G402	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.8097522271604528	[680]	[418,386,551,520]	-7	hSpCas9	negative selection	6946705
78165017	78165040	15	+	27260156	L33	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	0.05631297089345488	[166]	[201,47,145,142]	1	hSpCas9	negative selection	7003696
78164984	78165007	15	+	27260156	L33	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.1336494431883264	[1067]	[1008,558,794,1053]	3	hSpCas9	negative selection	7003697
78155206	78155229	15	+	27260156	L33	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.33720428663063756	[552]	[512,184,221,430]	-7	hSpCas9	negative selection	7003698
78160084	78160107	15	+	27260156	L33	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.21923809711100894	[719]	[637,273,373,571]	-5	hSpCas9	negative selection	7067954
78160145	78160168	15	+	27260156	L33	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.2391416876976462	[283]	[207,90,200,213]	-5	hSpCas9	negative selection	7067955
78157551	78157574	15	+	27260156	L33	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.3984535129204978	[680]	[535,184,347,524]	-7	hSpCas9	negative selection	7067956
78165017	78165040	15	+	27260156	K562	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.9592264599418705	[166]	[52,25,36,36]	-9	hSpCas9	negative selection	7124947
78164984	78165007	15	+	27260156	K562	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	-0.08848672471121866	[1067]	[994,741,854,961]	-1	hSpCas9	negative selection	7124948
78155206	78155229	15	+	27260156	K562	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.26603835308265916	[552]	[764,173,275,429]	-3	hSpCas9	negative selection	7124949
78160084	78160107	15	+	27260156	K562	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-1.6957164213264546	[719]	[244,233,117,196]	-9	hSpCas9	negative selection	7189205
78160145	78160168	15	+	27260156	K562	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-1.447945887592979	[283]	[95,56,31,172]	-9	hSpCas9	negative selection	7189206
78157551	78157574	15	+	27260156	K562	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.4139081508647442	[680]	[589,517,481,259]	-5	hSpCas9	negative selection	7189207
78165017	78165040	15	+	27260156	HT29	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.8282111698504879	[166]	[99,86,168,98]	-8	hSpCas9	negative selection	7246198
78164984	78165007	15	+	27260156	HT29	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.10702263876392326	[1067]	[1399,1592,1489,1147]	2	hSpCas9	negative selection	7246199
78155206	78155229	15	+	27260156	HT29	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.17145894925433774	[552]	[645,671,572,512]	-3	hSpCas9	negative selection	7246200
78160084	78160107	15	+	27260156	HT29	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.7805370986871092	[719]	[595,521,386,533]	-8	hSpCas9	negative selection	7310456
78160145	78160168	15	+	27260156	HT29	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.9840285409230366	[283]	[146,196,162,187]	-8	hSpCas9	negative selection	7310457
78157551	78157574	15	+	27260156	HT29	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.4043037803723921	[680]	[617,761,703,446]	-6	hSpCas9	negative selection	7310458
78165017	78165040	15	+	27260156	MHHES1	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.04039372657502893	[166]	[239,194,278,52]	0	hSpCas9	negative selection	7367449
78164984	78165007	15	+	27260156	MHHES1	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.4058446870253589	[1067]	[1567,1573,1590,1597]	7	hSpCas9	negative selection	7367450
78155206	78155229	15	+	27260156	MHHES1	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.2706288803736764	[552]	[548,573,547,415]	-5	hSpCas9	negative selection	7367451
78160084	78160107	15	+	27260156	MHHES1	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.25257325274995823	[719]	[768,686,613,653]	-5	hSpCas9	negative selection	7431707
78160145	78160168	15	+	27260156	MHHES1	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.06311320304980439	[283]	[169,395,482,189]	-1	hSpCas9	negative selection	7431708
78157551	78157574	15	+	27260156	MHHES1	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.09667142733475581	[680]	[1058,837,672,408]	-2	hSpCas9	negative selection	7431709
78165017	78165040	15	+	27260156	MEWO	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.07813391805180037	[166]	[163,162,119]	-2	hSpCas9	negative selection	7488700
78164984	78165007	15	+	27260156	MEWO	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.05280976361384049	[1067]	[1035,1032,1039]	1	hSpCas9	negative selection	7488701
78155206	78155229	15	+	27260156	MEWO	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.27836197563931064	[552]	[449,464,368]	-6	hSpCas9	negative selection	7488702
78160084	78160107	15	+	27260156	MEWO	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.1263092066759462	[719]	[645,589,620]	-3	hSpCas9	negative selection	7552958
78160145	78160168	15	+	27260156	MEWO	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.8722397411342987	[283]	[188,127,126]	-9	hSpCas9	negative selection	7552959
78157551	78157574	15	+	27260156	MEWO	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.16575059178353163	[680]	[597,484,626]	-4	hSpCas9	negative selection	7552960
78165017	78165040	15	+	27260156	LNCAPCLONEFGC	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.6764172542302895	[166]	[78,78,128,97]	-7	hSpCas9	negative selection	7609951
78164984	78165007	15	+	27260156	LNCAPCLONEFGC	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.3821705974428353	[1067]	[1243,1173,1484,1178]	6	hSpCas9	negative selection	7609952
78155206	78155229	15	+	27260156	LNCAPCLONEFGC	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.21107963037983465	[552]	[513,383,436,397]	-3	hSpCas9	negative selection	7609953
78160084	78160107	15	+	27260156	LNCAPCLONEFGC	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.29813621832245774	[719]	[467,515,613,537]	-5	hSpCas9	negative selection	7674209
78160145	78160168	15	+	27260156	LNCAPCLONEFGC	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.813275325896417	[283]	[84,116,269,134]	-8	hSpCas9	negative selection	7674210
78157551	78157574	15	+	27260156	LNCAPCLONEFGC	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.25132504131076683	[680]	[406,567,628,483]	-4	hSpCas9	negative selection	7674211
78165017	78165040	15	+	27260156	PANC0327	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.9124968014188433	[166]	[103,42,120,53]	-8	hSpCas9	negative selection	7731202
78164984	78165007	15	+	27260156	PANC0327	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.30230157641634015	[1067]	[1049,1002,1325,1311]	4	hSpCas9	negative selection	7731203
78155206	78155229	15	+	27260156	PANC0327	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	0.11813582906014766	[552]	[620,432,296,800]	1	hSpCas9	negative selection	7731204
78160084	78160107	15	+	27260156	PANC0327	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-1.4144991760058392	[719]	[130,268,269,276]	-9	hSpCas9	negative selection	7795460
78160145	78160168	15	+	27260156	PANC0327	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-1.9374293485568241	[283]	[30,108,54,59]	-9	hSpCas9	negative selection	7795461
78157551	78157574	15	+	27260156	PANC0327	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.3798457323388993	[680]	[551,561,371,367]	-5	hSpCas9	negative selection	7795462
78165017	78165040	15	+	27260156	NCIH2009	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.91136594324183	[166]	[88,78,22]	-9	hSpCas9	negative selection	7852453
78164984	78165007	15	+	27260156	NCIH2009	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.03019157454130572	[1067]	[1854,1195,1588]	0	hSpCas9	negative selection	7852454
78155206	78155229	15	+	27260156	NCIH2009	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.40900020943968535	[552]	[822,436,534]	-5	hSpCas9	negative selection	7852455
78160084	78160107	15	+	27260156	NCIH2009	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-1.172841550634037	[719]	[495,481,368]	-8	hSpCas9	negative selection	7916711
78160145	78160168	15	+	27260156	NCIH2009	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-2.069347994063011	[283]	[103,57,123]	-9	hSpCas9	negative selection	7916712
78157551	78157574	15	+	27260156	NCIH2009	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.5928741794479669	[680]	[711,712,480]	-6	hSpCas9	negative selection	7916713
78165017	78165040	15	+	27260156	NCIH1373	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.4688188409731202	[166]	[127,40,27,22]	-9	hSpCas9	negative selection	7973704
78164984	78165007	15	+	27260156	NCIH1373	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.304482401014349	[1067]	[2728,1167,1069,303]	3	hSpCas9	negative selection	7973705
78155206	78155229	15	+	27260156	NCIH1373	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.02803513513729558	[552]	[681,566,712,123]	0	hSpCas9	negative selection	7973706
78160084	78160107	15	+	27260156	NCIH1373	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-2.2892255995690007	[719]	[125,106,211,56]	-9	hSpCas9	negative selection	8037962
78160145	78160168	15	+	27260156	NCIH1373	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	0.43740510929466786	[283]	[345,228,92,291]	4	hSpCas9	negative selection	8037963
78157551	78157574	15	+	27260156	NCIH1373	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.3094801393871378	[680]	[1124,464,393,150]	-3	hSpCas9	negative selection	8037964
78165017	78165040	15	+	27260156	PATU8902	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-2.5724401942101327	[166]	[31,67,4,62]	-9	hSpCas9	negative selection	8094955
78164984	78165007	15	+	27260156	PATU8902	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.23072217065008527	[1067]	[1600,2409,1084,2087]	2	hSpCas9	negative selection	8094956
78155206	78155229	15	+	27260156	PATU8902	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.5498901974740674	[552]	[291,473,754,521]	-5	hSpCas9	negative selection	8094957
78160084	78160107	15	+	27260156	PATU8902	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-2.0518183874284843	[719]	[286,139,252,286]	-9	hSpCas9	negative selection	8159213
78160145	78160168	15	+	27260156	PATU8902	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-1.7224527342096803	[283]	[104,58,118,205]	-8	hSpCas9	negative selection	8159214
78157551	78157574	15	+	27260156	PATU8902	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.9192965548332872	[680]	[322,257,634,786]	-7	hSpCas9	negative selection	8159215
78165017	78165040	15	+	27260156	PANC1	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.12394900727960678	[166]	[143,168,110,110]	-2	hSpCas9	negative selection	8216206
78164984	78165007	15	+	27260156	PANC1	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	-0.08038024121680443	[1067]	[792,1040,926,751]	-1	hSpCas9	negative selection	8216207
78155206	78155229	15	+	27260156	PANC1	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.13170400338084448	[552]	[390,623,416,348]	-2	hSpCas9	negative selection	8216208
78160084	78160107	15	+	27260156	PANC1	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.4226417128701867	[719]	[380,657,555,310]	-6	hSpCas9	negative selection	8280464
78160145	78160168	15	+	27260156	PANC1	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.3026350821194236	[283]	[231,180,176,193]	-5	hSpCas9	negative selection	8280465
78157551	78157574	15	+	27260156	PANC1	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.41395515403284266	[680]	[337,396,619,395]	-6	hSpCas9	negative selection	8280466
78165017	78165040	15	+	27260156	PANC0813	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.7686478400443595	[166]	[87,155,136,78]	-8	hSpCas9	negative selection	8337457
78164984	78165007	15	+	27260156	PANC0813	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	-0.0075749187937490525	[1067]	[1554,1248,1243,984]	0	hSpCas9	negative selection	8337458
78155206	78155229	15	+	27260156	PANC0813	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.2655413074805958	[552]	[612,708,336,508]	-4	hSpCas9	negative selection	8337459
78160084	78160107	15	+	27260156	PANC0813	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-1.28268304443998	[719]	[498,407,286,216]	-9	hSpCas9	negative selection	8401715
78160145	78160168	15	+	27260156	PANC0813	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-1.5715447018261783	[283]	[138,91,103,115]	-9	hSpCas9	negative selection	8401716
78157551	78157574	15	+	27260156	PANC0813	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-1.1122480764712672	[680]	[499,330,321,339]	-8	hSpCas9	negative selection	8401717
78165017	78165040	15	+	27260156	RDES	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.7733706865152397	[166]	[97,108,144,95]	-8	hSpCas9	negative selection	8458708
78164984	78165007	15	+	27260156	RDES	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.18347575163340202	[1067]	[1034,1292,1730,1613]	3	hSpCas9	negative selection	8458709
78155206	78155229	15	+	27260156	RDES	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.42405665235816165	[552]	[411,488,411,595]	-6	hSpCas9	negative selection	8458710
78160084	78160107	15	+	27260156	RDES	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.3744713264172625	[719]	[455,480,791,910]	-6	hSpCas9	negative selection	8522966
78160145	78160168	15	+	27260156	RDES	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.5722248801122328	[283]	[161,344,118,245]	-7	hSpCas9	negative selection	8522967
78157551	78157574	15	+	27260156	RDES	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.19929504421694405	[680]	[611,563,751,830]	-3	hSpCas9	negative selection	8522968
78165017	78165040	15	+	27260156	PC3	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.39580800924506865	[166]	[103,76,306,83]	-7	hSpCas9	negative selection	8579959
78164984	78165007	15	+	27260156	PC3	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.2995508322007574	[1067]	[645,1497,2301,1358]	6	hSpCas9	negative selection	8579960
78155206	78155229	15	+	27260156	PC3	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.46761411536407205	[552]	[208,378,777,428]	-8	hSpCas9	negative selection	8579961
78160084	78160107	15	+	27260156	PC3	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.6284195637675382	[719]	[332,365,834,480]	-8	hSpCas9	negative selection	8644217
78160145	78160168	15	+	27260156	PC3	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.09932241398083808	[283]	[225,313,386,151]	-2	hSpCas9	negative selection	8644218
78157551	78157574	15	+	27260156	PC3	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.19051945333637071	[680]	[299,440,1263,732]	-4	hSpCas9	negative selection	8644219
78165017	78165040	15	+	27260156	PATU8988T	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.7196369675846936	[166]	[34,54,41,65]	-9	hSpCas9	negative selection	8701210
78164984	78165007	15	+	27260156	PATU8988T	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	-0.08842781663481047	[1067]	[1051,946,862,1023]	-1	hSpCas9	negative selection	8701211
78155206	78155229	15	+	27260156	PATU8988T	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.22294171926507675	[552]	[442,452,296,655]	-4	hSpCas9	negative selection	8701212
78160084	78160107	15	+	27260156	PATU8988T	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.5954359129018155	[719]	[744,312,282,491]	-7	hSpCas9	negative selection	8765468
78160145	78160168	15	+	27260156	PATU8988T	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.3393492209677186	[283]	[314,239,73,244]	-5	hSpCas9	negative selection	8765469
78157551	78157574	15	+	27260156	PATU8988T	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.8494195365786449	[680]	[310,506,292,363]	-8	hSpCas9	negative selection	8765470
78165017	78165040	15	+	27260156	T47D	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.1606990671073214	[166]	[188,146,214,145]	-4	hSpCas9	negative selection	8822461
78164984	78165007	15	+	27260156	T47D	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.23915118115232725	[1067]	[1415,1234,1647,1595]	5	hSpCas9	negative selection	8822462
78155206	78155229	15	+	27260156	T47D	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.23501434104590485	[552]	[649,446,461,643]	-5	hSpCas9	negative selection	8822463
78160084	78160107	15	+	27260156	T47D	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.3504962953628174	[719]	[656,606,668,703]	-6	hSpCas9	negative selection	8886719
78160145	78160168	15	+	27260156	T47D	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.6265344322560894	[283]	[196,180,208,274]	-8	hSpCas9	negative selection	8886720
78157551	78157574	15	+	27260156	T47D	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.21439937092958194	[680]	[607,704,693,726]	-5	hSpCas9	negative selection	8886721
78165017	78165040	15	+	27260156	SU8686	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.272934289024469	[166]	[36,63,89,90]	-9	hSpCas9	negative selection	8943712
78164984	78165007	15	+	27260156	SU8686	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.0349244775122135	[1067]	[884,850,1310,1393]	0	hSpCas9	negative selection	8943713
78155206	78155229	15	+	27260156	SU8686	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.05484291524076934	[552]	[483,544,452,644]	-1	hSpCas9	negative selection	8943714
78160084	78160107	15	+	27260156	SU8686	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-1.177164136082764	[719]	[277,304,346,340]	-9	hSpCas9	negative selection	9007970
78160145	78160168	15	+	27260156	SU8686	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-1.0788726299453253	[283]	[70,142,177,149]	-8	hSpCas9	negative selection	9007971
78157551	78157574	15	+	27260156	SU8686	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.7699482357865336	[680]	[270,351,407,603]	-8	hSpCas9	negative selection	9007972
78165017	78165040	15	+	27260156	SKES1	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.39439228950018834	[166]	[194,102,152,67]	-7	hSpCas9	negative selection	9064963
78164984	78165007	15	+	27260156	SKES1	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.1571732715041998	[1067]	[1233,1260,1041,1215]	3	hSpCas9	negative selection	9064964
78155206	78155229	15	+	27260156	SKES1	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.47879513888059044	[552]	[346,552,435,269]	-8	hSpCas9	negative selection	9064965
78160084	78160107	15	+	27260156	SKES1	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.42717005552332576	[719]	[543,580,586,436]	-7	hSpCas9	negative selection	9129221
78160145	78160168	15	+	27260156	SKES1	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.6709551281156253	[283]	[157,243,118,192]	-9	hSpCas9	negative selection	9129222
78157551	78157574	15	+	27260156	SKES1	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.2322034485279718	[680]	[539,581,622,558]	-5	hSpCas9	negative selection	9129223
78165017	78165040	15	+	27260156	TOV112D	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.09276977920111484	[166]	[147,163,45,266]	-2	hSpCas9	negative selection	9186214
78164984	78165007	15	+	27260156	TOV112D	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.15965182992364868	[1067]	[965,1239,1144,1411]	3	hSpCas9	negative selection	9186215
78155206	78155229	15	+	27260156	TOV112D	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.24963402636370854	[552]	[482,702,362,375]	-5	hSpCas9	negative selection	9186216
78160084	78160107	15	+	27260156	TOV112D	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.18656297096974822	[719]	[568,811,485,702]	-4	hSpCas9	negative selection	9250472
78160145	78160168	15	+	27260156	TOV112D	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.5658122514843645	[283]	[268,248,158,113]	-8	hSpCas9	negative selection	9250473
78157551	78157574	15	+	27260156	TOV112D	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.4865783399251373	[680]	[459,446,528,497]	-7	hSpCas9	negative selection	9250474
78165017	78165040	15	+	27260156	TC71	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.27434275708598665	[166]	[188,156,125,117]	-6	hSpCas9	negative selection	9307465
78164984	78165007	15	+	27260156	TC71	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	-0.10686186233016026	[1067]	[1165,1032,1013,1036]	-3	hSpCas9	negative selection	9307466
78155206	78155229	15	+	27260156	TC71	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.207944903659788	[552]	[560,438,546,502]	-5	hSpCas9	negative selection	9307467
78160084	78160107	15	+	27260156	TC71	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.23597067280548434	[719]	[700,654,627,635]	-6	hSpCas9	negative selection	9371723
78160145	78160168	15	+	27260156	TC71	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.5309144555374986	[283]	[186,194,219,242]	-9	hSpCas9	negative selection	9371724
78157551	78157574	15	+	27260156	TC71	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.3555086988892345	[680]	[434,675,623,546]	-7	hSpCas9	negative selection	9371725
78165017	78165040	15	+	27260156	TC32	viability	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.05575956441641505	[166]	[198,55,162,212]	-1	hSpCas9	negative selection	9428716
78164984	78165007	15	+	27260156	TC32	viability	TCCGCTAGTGACTTGTGTGCAGG	IDH3A	ENSG00000166411	0.3953240169031391	[1067]	[1405,999,1381,1543]	7	hSpCas9	negative selection	9428717
78155206	78155229	15	+	27260156	TC32	viability	AATATAGGTCTCTCGGCTGCTGG	IDH3A	ENSG00000166411	-0.5204278779121478	[552]	[318,252,483,444]	-7	hSpCas9	negative selection	9428718
78160084	78160107	15	+	27260156	TC32	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.13021638803784674	[719]	[589,529,843,541]	-2	hSpCas9	negative selection	9492974
78160145	78160168	15	+	27260156	TC32	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.8081490478192065	[283]	[137,57,240,221]	-9	hSpCas9	negative selection	9492975
78157551	78157574	15	+	27260156	TC32	viability	CAGACAGTAACTTTAATTCCAGG	IDH3A	ENSG00000166411	-0.16641411713035448	[680]	[645,375,799,525]	-3	hSpCas9	negative selection	9492976
78161667	78161690	15	-	27869803	HPAFII	viability after 27 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-3.4986843003263948	[214]	[15,4,NaN]	-9	hSpCas9	negative selection	9554935
78161722	78161745	15	-	27869803	HPAFII	viability after 27 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-0.9666519183618677	[146]	[56,24,NaN]	-6	hSpCas9	negative selection	9554936
78162310	78162333	15	+	27869803	HPAFII	viability after 27 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-1.4493890040696207	[118]	[41,6,NaN]	-7	hSpCas9	negative selection	9554937
78162326	78162349	15	+	27869803	HPAFII	viability after 27 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-1.146716598814129	[651]	[168,142,NaN]	-7	hSpCas9	negative selection	9554938
78165017	78165040	15	+	27869803	HPAFII	viability after 27 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-2.9406567098289234	[153]	[9,10,NaN]	-9	hSpCas9	negative selection	9554939
78166218	78166241	15	+	27869803	HPAFII	viability after 27 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	0.9275804543757036	[473]	[725,263,NaN]	7	hSpCas9	negative selection	9554940
78161667	78161690	15	-	27869803	HPAFII	viability after 15 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-1.9715560187184755	[214]	[61,56,NaN]	-9	hSpCas9	negative selection	9637384
78161722	78161745	15	-	27869803	HPAFII	viability after 15 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	0.06463615747325224	[146]	[245,114,NaN]	0	hSpCas9	negative selection	9637385
78162310	78162333	15	+	27869803	HPAFII	viability after 15 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.6116424200479909	[118]	[79,85,NaN]	-6	hSpCas9	negative selection	9637386
78162326	78162349	15	+	27869803	HPAFII	viability after 15 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-0.8983915550468884	[651]	[489,304,NaN]	-7	hSpCas9	negative selection	9637387
78165017	78165040	15	+	27869803	HPAFII	viability after 15 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-1.067205948613069	[153]	[123,50,NaN]	-8	hSpCas9	negative selection	9637388
78166218	78166241	15	+	27869803	HPAFII	viability after 15 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	0.8565051942135893	[473]	[1271,704,NaN]	8	hSpCas9	negative selection	9637389
78161667	78161690	15	-	27869803	ASPC1	viability after 36 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-0.7886135810148509	[403]	[137,23,86]	-6	hSpCas9	negative selection	9719833
78161722	78161745	15	-	27869803	ASPC1	viability after 36 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	0.02821488515543613	[425]	[130,111,195]	0	hSpCas9	negative selection	9719834
78162310	78162333	15	+	27869803	ASPC1	viability after 36 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-1.3141190197155277	[320]	[10,119,8]	-8	hSpCas9	negative selection	9719835
78162326	78162349	15	+	27869803	ASPC1	viability after 36 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-1.0767059118412179	[1438]	[290,384,81]	-8	hSpCas9	negative selection	9719836
78165017	78165040	15	+	27869803	ASPC1	viability after 36 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.19238912731347801	[365]	[148,177,31]	-2	hSpCas9	negative selection	9719837
78166218	78166241	15	+	27869803	ASPC1	viability after 36 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	0.5155571044827048	[1067]	[508,677,428]	5	hSpCas9	negative selection	9719838
78161667	78161690	15	-	27869803	PATU8988S	viability after 35 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-2.7021755356985224	[379]	[30,15,NaN]	-9	hSpCas9	negative selection	9802282
78161722	78161745	15	-	27869803	PATU8988S	viability after 35 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-2.525412900540476	[464]	[44,19,NaN]	-9	hSpCas9	negative selection	9802283
78162310	78162333	15	+	27869803	PATU8988S	viability after 35 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.17581376898019008	[296]	[58,152,NaN]	-2	hSpCas9	negative selection	9802284
78162326	78162349	15	+	27869803	PATU8988S	viability after 35 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-1.3391040276549548	[1393]	[184,258,NaN]	-8	hSpCas9	negative selection	9802285
78165017	78165040	15	+	27869803	PATU8988S	viability after 35 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.5081666279528749	[306]	[58,114,NaN]	-5	hSpCas9	negative selection	9802286
78166218	78166241	15	+	27869803	PATU8988S	viability after 35 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	0.4502466622346506	[1159]	[554,721,NaN]	5	hSpCas9	negative selection	9802287
78161667	78161690	15	-	27869803	PATU8988S	viability after 31 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-1.634632804994478	[379]	[39,59,NaN]	-8	hSpCas9	negative selection	9884731
78161722	78161745	15	-	27869803	PATU8988S	viability after 31 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-2.161591832894462	[464]	[51,27,NaN]	-9	hSpCas9	negative selection	9884732
78162310	78162333	15	+	27869803	PATU8988S	viability after 31 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	0.21254223577019726	[296]	[61,232,NaN]	2	hSpCas9	negative selection	9884733
78162326	78162349	15	+	27869803	PATU8988S	viability after 31 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-1.5379194705227544	[1393]	[113,289,NaN]	-8	hSpCas9	negative selection	9884734
78165017	78165040	15	+	27869803	PATU8988S	viability after 31 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-0.5881644669256754	[306]	[25,151,NaN]	-6	hSpCas9	negative selection	9884735
78166218	78166241	15	+	27869803	PATU8988S	viability after 31 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	0.6201442162061264	[1159]	[618,827,NaN]	7	hSpCas9	negative selection	9884736
78161667	78161690	15	-	27869803	HPAFII	viability after 35 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-3.2309365155301397	[214]	[20,0,NaN]	-8	hSpCas9	negative selection	9967180
78161722	78161745	15	-	27869803	HPAFII	viability after 35 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-2.0809877457928767	[146]	[18,15,NaN]	-8	hSpCas9	negative selection	9967181
78162310	78162333	15	+	27869803	HPAFII	viability after 35 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-1.0992775259437284	[118]	[29,25,NaN]	-6	hSpCas9	negative selection	9967182
78162326	78162349	15	+	27869803	HPAFII	viability after 35 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-1.025347131872412	[651]	[132,194,NaN]	-5	hSpCas9	negative selection	9967183
78165017	78165040	15	+	27869803	HPAFII	viability after 35 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-3.8970041555853188	[153]	[0,9,NaN]	-9	hSpCas9	negative selection	9967184
78166218	78166241	15	+	27869803	HPAFII	viability after 35 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	1.217129340638893	[473]	[769,318,NaN]	7	hSpCas9	negative selection	9967185
78161667	78161690	15	-	27869803	HPAFII	viability after 31 days	TAGCCTTCGATAGAGACACATGG	IDH3A	ENSG00000166411	-2.108202984591582	[214]	[49,3,NaN]	-8	hSpCas9	negative selection	10049629
78161722	78161745	15	-	27869803	HPAFII	viability after 31 days	TCCTTCTGTGTTCTCTCGAATGG	IDH3A	ENSG00000166411	-0.8917260402632675	[146]	[65,20,NaN]	-5	hSpCas9	negative selection	10049630
78162310	78162333	15	+	27869803	HPAFII	viability after 31 days	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.7104442596412806	[118]	[58,20,NaN]	-4	hSpCas9	negative selection	10049631
78162326	78162349	15	+	27869803	HPAFII	viability after 31 days	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-1.5062881660580119	[651]	[90,169,NaN]	-7	hSpCas9	negative selection	10049632
78165017	78165040	15	+	27869803	HPAFII	viability after 31 days	GGTCTCGGTGTGACACCAAGTGG	IDH3A	ENSG00000166411	-4.2161846247989745	[153]	[7,0,NaN]	-9	hSpCas9	negative selection	10049633
78166218	78166241	15	+	27869803	HPAFII	viability after 31 days	CGTGATGATGCTGCGCCACATGG	IDH3A	ENSG00000166411	1.1851808012389515	[473]	[758,436,NaN]	8	hSpCas9	negative selection	10049634
78160084	78160107	15	+	28162770	P31FUJ	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	1.0727003425598727	[52]	[130]	9	hSpCas9	negative selection	10172546
78160145	78160168	15	+	28162770	P31FUJ	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.46703623839534286	[366]	[311]	-4	hSpCas9	negative selection	10172547
78160122	78160145	15	+	28162770	P31FUJ	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	0.13339615740049982	[352]	[454]	1	hSpCas9	negative selection	10172548
78162254	78162277	15	+	28162770	P31FUJ	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	0.25046489923742676	[190]	[266]	2	hSpCas9	negative selection	10172549
78162310	78162333	15	+	28162770	P31FUJ	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	0.28245132449537314	[211]	[302]	3	hSpCas9	negative selection	10172550
78162326	78162349	15	+	28162770	P31FUJ	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	0.473466592528911	[94]	[154]	5	hSpCas9	negative selection	10172551
78149414	78149437	15	-	28162770	P31FUJ	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	0.40462771620091303	[224]	[349]	4	hSpCas9	negative selection	10172552
78161733	78161756	15	+	28162770	P31FUJ	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	-0.33444246629021623	[146]	[136]	-3	hSpCas9	negative selection	10172553
78155240	78155263	15	+	28162770	P31FUJ	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	-1.2328022044143783	[15]	[7]	-7	hSpCas9	negative selection	10172554
78155252	78155275	15	+	28162770	P31FUJ	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	-0.3762343078780981	[316]	[286]	-3	hSpCas9	negative selection	10172555
78160084	78160107	15	+	28162770	TF1	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10341912
78160145	78160168	15	+	28162770	TF1	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10341913
78160122	78160145	15	+	28162770	TF1	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10341914
78162254	78162277	15	+	28162770	TF1	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10341915
78162310	78162333	15	+	28162770	TF1	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10341916
78162326	78162349	15	+	28162770	TF1	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10341917
78149414	78149437	15	-	28162770	TF1	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	NaN	[NaN]	[28]	1	hSpCas9	negative selection	10341918
78161733	78161756	15	+	28162770	TF1	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10341919
78155240	78155263	15	+	28162770	TF1	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10341920
78155252	78155275	15	+	28162770	TF1	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	NaN	[NaN]	[185]	1	hSpCas9	negative selection	10341921
78160084	78160107	15	+	28162770	SKM1	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.5996092766855575	[29]	[34]	-5	hSpCas9	negative selection	10511278
78160145	78160168	15	+	28162770	SKM1	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	0.3765439813600748	[60]	[139]	3	hSpCas9	negative selection	10511279
78160122	78160145	15	+	28162770	SKM1	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	0.9427470526577386	[107]	[366]	8	hSpCas9	negative selection	10511280
78162254	78162277	15	+	28162770	SKM1	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	-0.5243211493813205	[47]	[58]	-4	hSpCas9	negative selection	10511281
78162310	78162333	15	+	28162770	SKM1	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.39066238641406126	[65]	[88]	-3	hSpCas9	negative selection	10511282
78162326	78162349	15	+	28162770	SKM1	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	0.2154730073966571	[18]	[38]	2	hSpCas9	negative selection	10511283
78149414	78149437	15	-	28162770	SKM1	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	1.142374392247273	[40]	[159]	9	hSpCas9	negative selection	10511284
78161733	78161756	15	+	28162770	SKM1	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	0.08178298671869133	[30]	[57]	0	hSpCas9	negative selection	10511285
78155240	78155263	15	+	28162770	SKM1	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	2.177998301977995	[1]	[15]	9	hSpCas9	negative selection	10511286
78155252	78155275	15	+	28162770	SKM1	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	-0.9595052217719404	[76]	[69]	-6	hSpCas9	negative selection	10511287
78160084	78160107	15	+	28162770	SKM1	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.5996092766855575	[29]	[34]	-5	hSpCas9	negative selection	10680644
78160145	78160168	15	+	28162770	SKM1	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	0.3765439813600748	[60]	[139]	3	hSpCas9	negative selection	10680645
78160122	78160145	15	+	28162770	SKM1	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	0.9427470526577386	[107]	[366]	8	hSpCas9	negative selection	10680646
78162254	78162277	15	+	28162770	SKM1	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	-0.5243211493813205	[47]	[58]	-4	hSpCas9	negative selection	10680647
78162310	78162333	15	+	28162770	SKM1	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.39066238641406126	[65]	[88]	-3	hSpCas9	negative selection	10680648
78162326	78162349	15	+	28162770	SKM1	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	0.2154730073966571	[18]	[38]	2	hSpCas9	negative selection	10680649
78149414	78149437	15	-	28162770	SKM1	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	1.142374392247273	[40]	[159]	9	hSpCas9	negative selection	10680650
78161733	78161756	15	+	28162770	SKM1	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	0.08178298671869133	[30]	[57]	0	hSpCas9	negative selection	10680651
78155240	78155263	15	+	28162770	SKM1	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	2.177998301977995	[1]	[15]	9	hSpCas9	negative selection	10680652
78155252	78155275	15	+	28162770	SKM1	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	-0.9595052217719404	[76]	[69]	-6	hSpCas9	negative selection	10680653
78160084	78160107	15	+	28162770	PL21	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	0.35625881640660184	[69]	[38]	3	hSpCas9	negative selection	10850010
78160145	78160168	15	+	28162770	PL21	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	1.0688950812110676	[160]	[146]	8	hSpCas9	negative selection	10850011
78160122	78160145	15	+	28162770	PL21	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	-0.026929294056600828	[411]	[175]	0	hSpCas9	negative selection	10850012
78162254	78162277	15	+	28162770	PL21	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	-0.11417529628816708	[188]	[75]	-1	hSpCas9	negative selection	10850013
78162310	78162333	15	+	28162770	PL21	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	0.5210256760768562	[276]	[172]	4	hSpCas9	negative selection	10850014
78162326	78162349	15	+	28162770	PL21	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	0.35214270793436997	[71]	[39]	3	hSpCas9	negative selection	10850015
78149414	78149437	15	-	28162770	PL21	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	0.13223554998751666	[173]	[82]	1	hSpCas9	negative selection	10850016
78161733	78161756	15	+	28162770	PL21	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	0.8929581049711439	[72]	[58]	7	hSpCas9	negative selection	10850017
78155240	78155263	15	+	28162770	PL21	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	-2.6072153075682842	[13]	[0]	-9	hSpCas9	negative selection	10850018
78155252	78155275	15	+	28162770	PL21	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	-0.1065217237447319	[234]	[94]	-1	hSpCas9	negative selection	10850019
78160084	78160107	15	+	28162770	P31FUJ	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	1.0727003425598727	[52]	[130]	9	hSpCas9	negative selection	11019376
78160145	78160168	15	+	28162770	P31FUJ	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.46703623839534286	[366]	[311]	-4	hSpCas9	negative selection	11019377
78160122	78160145	15	+	28162770	P31FUJ	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	0.13339615740049982	[352]	[454]	1	hSpCas9	negative selection	11019378
78162254	78162277	15	+	28162770	P31FUJ	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	0.25046489923742676	[190]	[266]	2	hSpCas9	negative selection	11019379
78162310	78162333	15	+	28162770	P31FUJ	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	0.28245132449537314	[211]	[302]	3	hSpCas9	negative selection	11019380
78162326	78162349	15	+	28162770	P31FUJ	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	0.473466592528911	[94]	[154]	5	hSpCas9	negative selection	11019381
78149414	78149437	15	-	28162770	P31FUJ	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	0.40462771620091303	[224]	[349]	4	hSpCas9	negative selection	11019382
78161733	78161756	15	+	28162770	P31FUJ	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	-0.33444246629021623	[146]	[136]	-3	hSpCas9	negative selection	11019383
78155240	78155263	15	+	28162770	P31FUJ	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	-1.2328022044143783	[15]	[7]	-7	hSpCas9	negative selection	11019384
78155252	78155275	15	+	28162770	P31FUJ	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	-0.3762343078780981	[316]	[286]	-3	hSpCas9	negative selection	11019385
78160084	78160107	15	+	28162770	OCIAML5	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.4191071635878907	[39]	[53]	-3	hSpCas9	negative selection	11188742
78160145	78160168	15	+	28162770	OCIAML5	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.2829059262657338	[152]	[226]	-2	hSpCas9	negative selection	11188743
78160122	78160145	15	+	28162770	OCIAML5	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	-0.5091788573409886	[204]	[259]	-4	hSpCas9	negative selection	11188744
78162254	78162277	15	+	28162770	OCIAML5	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	0.18464520749252422	[96]	[198]	1	hSpCas9	negative selection	11188745
78162310	78162333	15	+	28162770	OCIAML5	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.8606285843674211	[168]	[167]	-5	hSpCas9	negative selection	11188746
78162326	78162349	15	+	28162770	OCIAML5	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-1.893886746558624	[34]	[16]	-7	hSpCas9	negative selection	11188747
78149414	78149437	15	-	28162770	OCIAML5	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-0.501309822917416	[108]	[138]	-3	hSpCas9	negative selection	11188748
78161733	78161756	15	+	28162770	OCIAML5	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	-1.1103785664553876	[60]	[50]	-6	hSpCas9	negative selection	11188749
78155240	78155263	15	+	28162770	OCIAML5	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	1.294774817465274	[6]	[30]	9	hSpCas9	negative selection	11188750
78155252	78155275	15	+	28162770	OCIAML5	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	0.1708702404131618	[155]	[316]	1	hSpCas9	negative selection	11188751
78160084	78160107	15	+	28162770	EOL1	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	0.47388636256096917	[122]	[89]	4	hSpCas9	negative selection	11358108
78160145	78160168	15	+	28162770	EOL1	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	0.010477950357710583	[276]	[146]	0	hSpCas9	negative selection	11358109
78160122	78160145	15	+	28162770	EOL1	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	0.4212237398737355	[729]	[514]	4	hSpCas9	negative selection	11358110
78162254	78162277	15	+	28162770	EOL1	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	-0.8751535779436344	[375]	[107]	-6	hSpCas9	negative selection	11358111
78162310	78162333	15	+	28162770	EOL1	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	0.1126201197231062	[394]	[224]	1	hSpCas9	negative selection	11358112
78162326	78162349	15	+	28162770	EOL1	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-0.952769708654637	[168]	[45]	-6	hSpCas9	negative selection	11358113
78149414	78149437	15	-	28162770	EOL1	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-0.5516012420116962	[216]	[77]	-4	hSpCas9	negative selection	11358114
78161733	78161756	15	+	28162770	EOL1	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	-1.7535241335421032	[127]	[19]	-8	hSpCas9	negative selection	11358115
78155240	78155263	15	+	28162770	EOL1	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	0.38397939020783145	[15]	[10]	3	hSpCas9	negative selection	11358116
78155252	78155275	15	+	28162770	EOL1	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	0.2326700669328664	[314]	[194]	2	hSpCas9	negative selection	11358117
78160084	78160107	15	+	28162770	MOLM13	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.6237410939209893	[129]	[60]	-4	hSpCas9	negative selection	11527474
78160145	78160168	15	+	28162770	MOLM13	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-2.2189527331957906	[263]	[40]	-7	hSpCas9	negative selection	11527475
78160122	78160145	15	+	28162770	MOLM13	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	0.25912024407210577	[526]	[455]	1	hSpCas9	negative selection	11527476
78162254	78162277	15	+	28162770	MOLM13	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	-0.48206993595582565	[254]	[131]	-3	hSpCas9	negative selection	11527477
78162310	78162333	15	+	28162770	MOLM13	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.41366916115788177	[373]	[202]	-2	hSpCas9	negative selection	11527478
78162326	78162349	15	+	28162770	MOLM13	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-1.4423139481047753	[108]	[28]	-6	hSpCas9	negative selection	11527479
78149414	78149437	15	-	28162770	MOLM13	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-0.5942323303632189	[260]	[124]	-3	hSpCas9	negative selection	11527480
78161733	78161756	15	+	28162770	MOLM13	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	-1.5781230162122575	[222]	[53]	-7	hSpCas9	negative selection	11527481
78155240	78155263	15	+	28162770	MOLM13	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	-2.4065797363715618	[21]	[2]	-8	hSpCas9	negative selection	11527482
78155252	78155275	15	+	28162770	MOLM13	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	0.06167573265274107	[325]	[245]	0	hSpCas9	negative selection	11527483
78160084	78160107	15	+	28162770	HEL	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.9032295371049357	[145]	[49]	-5	hSpCas9	negative selection	11696840
78160145	78160168	15	+	28162770	HEL	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-1.8658105532016311	[238]	[41]	-7	hSpCas9	negative selection	11696841
78160122	78160145	15	+	28162770	HEL	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	-0.8779504548423496	[438]	[152]	-5	hSpCas9	negative selection	11696842
78162254	78162277	15	+	28162770	HEL	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	-3.1760208533294962	[253]	[17]	-9	hSpCas9	negative selection	11696843
78162310	78162333	15	+	28162770	HEL	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-3.2742405812317457	[286]	[18]	-9	hSpCas9	negative selection	11696844
78162326	78162349	15	+	28162770	HEL	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-3.395396296886415	[114]	[6]	-9	hSpCas9	negative selection	11696845
78149414	78149437	15	-	28162770	HEL	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-0.4852687803757143	[211]	[96]	-3	hSpCas9	negative selection	11696846
78161733	78161756	15	+	28162770	HEL	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	-3.512539393477554	[195]	[10]	-9	hSpCas9	negative selection	11696847
78155240	78155263	15	+	28162770	HEL	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	-0.4567968415505579	[14]	[6]	-3	hSpCas9	negative selection	11696848
78155252	78155275	15	+	28162770	HEL	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	-0.5883602846869903	[276]	[117]	-4	hSpCas9	negative selection	11696849
78160084	78160107	15	+	28162770	MV411	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	0.42328738618219286	[53]	[60]	4	hSpCas9	negative selection	11866206
78160145	78160168	15	+	28162770	MV411	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.5846178119031533	[161]	[90]	-4	hSpCas9	negative selection	11866207
78160122	78160145	15	+	28162770	MV411	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	0.2951039844130896	[386]	[399]	2	hSpCas9	negative selection	11866208
78162254	78162277	15	+	28162770	MV411	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	-0.5137755896301082	[199]	[117]	-4	hSpCas9	negative selection	11866209
78162310	78162333	15	+	28162770	MV411	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.651799472282308	[234]	[125]	-4	hSpCas9	negative selection	11866210
78162326	78162349	15	+	28162770	MV411	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-0.5879317474444252	[90]	[50]	-4	hSpCas9	negative selection	11866211
78149414	78149437	15	-	28162770	MV411	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-0.035201412990529896	[162]	[133]	0	hSpCas9	negative selection	11866212
78161733	78161756	15	+	28162770	MV411	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	-0.6478650705505316	[92]	[49]	-4	hSpCas9	negative selection	11866213
78155240	78155263	15	+	28162770	MV411	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	4.05479247284038	[2]	[41]	9	hSpCas9	negative selection	11866214
78155252	78155275	15	+	28162770	MV411	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	-0.27910826371305886	[241]	[167]	-2	hSpCas9	negative selection	11866215
78160084	78160107	15	+	28162770	MONOMAC1	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-0.19703684705955382	[36]	[36]	-2	hSpCas9	negative selection	12035572
78160145	78160168	15	+	28162770	MONOMAC1	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.4258555375554346	[149]	[127]	-4	hSpCas9	negative selection	12035573
78160122	78160145	15	+	28162770	MONOMAC1	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	-1.0001213317389293	[252]	[144]	-7	hSpCas9	negative selection	12035574
78162254	78162277	15	+	28162770	MONOMAC1	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	-0.5631647458574511	[115]	[89]	-5	hSpCas9	negative selection	12035575
78162310	78162333	15	+	28162770	MONOMAC1	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	-0.7990728611396513	[169]	[111]	-6	hSpCas9	negative selection	12035576
78162326	78162349	15	+	28162770	MONOMAC1	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	0.13638688666563814	[49]	[62]	1	hSpCas9	negative selection	12035577
78149414	78149437	15	-	28162770	MONOMAC1	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-0.5222776759877519	[108]	[86]	-4	hSpCas9	negative selection	12035578
78161733	78161756	15	+	28162770	MONOMAC1	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	-0.9503968794764288	[58]	[34]	-6	hSpCas9	negative selection	12035579
78155240	78155263	15	+	28162770	MONOMAC1	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	-2.78199934778071	[5]	[0]	-9	hSpCas9	negative selection	12035580
78155252	78155275	15	+	28162770	MONOMAC1	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	0.054881526580066065	[151]	[180]	0	hSpCas9	negative selection	12035581
78160084	78160107	15	+	28162770	OCIAML2	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	-1.1130778206240775	[31]	[81]	-6	hSpCas9	negative selection	12204938
78160145	78160168	15	+	28162770	OCIAML2	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	-0.018503007228097258	[35]	[196]	0	hSpCas9	negative selection	12204939
78160122	78160145	15	+	28162770	OCIAML2	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	0.7709561613275977	[71]	[680]	7	hSpCas9	negative selection	12204940
78162254	78162277	15	+	28162770	OCIAML2	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	-0.4431490888200543	[38]	[158]	-3	hSpCas9	negative selection	12204941
78162310	78162333	15	+	28162770	OCIAML2	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	0.3729074331220889	[44]	[322]	3	hSpCas9	negative selection	12204942
78162326	78162349	15	+	28162770	OCIAML2	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	-0.470629825242161	[14]	[59]	-4	hSpCas9	negative selection	12204943
78149414	78149437	15	-	28162770	OCIAML2	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-0.29518781883228307	[28]	[130]	-2	hSpCas9	negative selection	12204944
78161733	78161756	15	+	28162770	OCIAML2	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	-0.6632749031845571	[23]	[83]	-5	hSpCas9	negative selection	12204945
78155240	78155263	15	+	28162770	OCIAML2	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	-1.733664231075955	[2]	[4]	-8	hSpCas9	negative selection	12204946
78155252	78155275	15	+	28162770	OCIAML2	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	0.5899117166928896	[34]	[291]	6	hSpCas9	negative selection	12204947
78160084	78160107	15	+	28162770	OCIAML3	viability	GCATCTAGGCACCTATTCAGTGG	IDH3A	ENSG00000166411	0.8784801311385804	[19]	[110]	7	hSpCas9	negative selection	12374304
78160145	78160168	15	+	28162770	OCIAML3	viability	AAAGTGGATGATCCCTTCAGAGG	IDH3A	ENSG00000166411	0.3115276756723445	[70]	[265]	3	hSpCas9	negative selection	12374305
78160122	78160145	15	+	28162770	OCIAML3	viability	ACTGCCATTCAAGGACCTGGAGG	IDH3A	ENSG00000166411	0.38220179634108575	[106]	[420]	3	hSpCas9	negative selection	12374306
78162254	78162277	15	+	28162770	OCIAML3	viability	GAGTATCAAGCTCATCACCGAGG	IDH3A	ENSG00000166411	0.742275747540269	[39]	[201]	6	hSpCas9	negative selection	12374307
78162310	78162333	15	+	28162770	OCIAML3	viability	AGTATGCCCGGAACAACCACCGG	IDH3A	ENSG00000166411	0.06782362378126361	[66]	[211]	0	hSpCas9	negative selection	12374308
78162326	78162349	15	+	28162770	OCIAML3	viability	CCACCGGAGCAACGTCACGGCGG	IDH3A	ENSG00000166411	0.5694910919587161	[24]	[111]	5	hSpCas9	negative selection	12374309
78149414	78149437	15	-	28162770	OCIAML3	viability	GCTCACCTTAGAGATCCACGCGG	IDH3A	ENSG00000166411	-1.066076084639386	[42]	[61]	-6	hSpCas9	negative selection	12374310
78161733	78161756	15	+	28162770	OCIAML3	viability	AACACAGAAGGAGAATACAGTGG	IDH3A	ENSG00000166411	0.6539198731194223	[19]	[94]	6	hSpCas9	negative selection	12374311
78155240	78155263	15	+	28162770	OCIAML3	viability	AACCCAAAACAGGTGACCAGAGG	IDH3A	ENSG00000166411	1.70977310785294	[7]	[78]	9	hSpCas9	negative selection	12374312
78155252	78155275	15	+	28162770	OCIAML3	viability	GTGACCAGAGGTTTTACTGGTGG	IDH3A	ENSG00000166411	-0.2110039686850324	[73]	[192]	-2	hSpCas9	negative selection	12374313