Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 3827
• Symbol: KNG1
• Description: kininogen 1

DataSource: http://genomecrispr.dkfz.de/#!/results/KNG1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
186725122	186725145	3	-	26472758	Jiyoye	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	1.021521689008124	[161]	[247]	6	hSpCas9	negative selection	85939
186732526	186732549	3	-	26472758	Jiyoye	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.1496791592135096	[207]	[173]	1	hSpCas9	negative selection	85940
186717578	186717601	3	+	26472758	Jiyoye	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.09380930012193511	[209]	[168]	0	hSpCas9	negative selection	85941
186722443	186722466	3	+	26472758	Jiyoye	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.5149786710403884	[115]	[124]	4	hSpCas9	negative selection	85942
186722472	186722495	3	+	26472758	Jiyoye	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.5121449411074158	[211]	[227]	4	hSpCas9	negative selection	85943
186732519	186732542	3	+	26472758	Jiyoye	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	-0.3886839017139012	[249]	[143]	-3	hSpCas9	negative selection	85944
186739403	186739426	3	-	26472758	Jiyoye	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	0.13464952669478186	[121]	[100]	1	hSpCas9	negative selection	85945
186717614	186717637	3	+	26472758	Jiyoye	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	1.5167998726803713	[18]	[40]	8	hSpCas9	negative selection	85946
186720150	186720173	3	+	26472758	Jiyoye	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	-0.17778711921528295	[101]	[67]	-1	hSpCas9	negative selection	85947
186717556	186717579	3	-	26472758	Jiyoye	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	1.1076150996469658	[39]	[64]	7	hSpCas9	negative selection	85948
186725122	186725145	3	-	26472758	KBM7	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.26972639459991726	[703,520]	[360,327]	3	hSpCas9	negative selection	277057
186732526	186732549	3	-	26472758	KBM7	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.7766004135402614	[796,845]	[705,631]	8	hSpCas9	negative selection	277058
186717578	186717601	3	+	26472758	KBM7	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.3584640372714863	[523,505]	[435,199]	4	hSpCas9	negative selection	277059
186722443	186722466	3	+	26472758	KBM7	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.2834699156456512	[807,533]	[191,543]	3	hSpCas9	negative selection	277060
186722472	186722495	3	+	26472758	KBM7	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.14126959633863206	[619,512]	[313,272]	1	hSpCas9	negative selection	277061
186732519	186732542	3	+	26472758	KBM7	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	0.58719164391397	[630,514]	[401,402]	6	hSpCas9	negative selection	277062
186739403	186739426	3	-	26472758	KBM7	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	0.25020134663847826	[401,326]	[151,247]	2	hSpCas9	negative selection	277063
186717614	186717637	3	+	26472758	KBM7	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	1.1391213807137166	[97,122]	[100,129]	9	hSpCas9	negative selection	277064
186720150	186720173	3	+	26472758	KBM7	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.4554184013190405	[385,416]	[201,313]	5	hSpCas9	negative selection	277065
186717556	186717579	3	-	26472758	KBM7	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	0.16514264875933782	[224,301]	[128,152]	1	hSpCas9	negative selection	277066
186725122	186725145	3	-	26472758	Raji	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.6334523470411872	[274]	[98]	6	hSpCas9	negative selection	468175
186732526	186732549	3	-	26472758	Raji	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.241134924262427	[524]	[143]	2	hSpCas9	negative selection	468176
186717578	186717601	3	+	26472758	Raji	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.6785402365697252	[244]	[90]	6	hSpCas9	negative selection	468177
186722443	186722466	3	+	26472758	Raji	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.3205574266806687	[313]	[90]	3	hSpCas9	negative selection	468178
186722472	186722495	3	+	26472758	Raji	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.8070782521860327	[297]	[120]	7	hSpCas9	negative selection	468179
186732519	186732542	3	+	26472758	Raji	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	-1.10206983025535	[406]	[43]	-7	hSpCas9	negative selection	468180
186739403	186739426	3	-	26472758	Raji	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	0.7310076564638606	[134]	[51]	6	hSpCas9	negative selection	468181
186717614	186717637	3	+	26472758	Raji	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	0.48177905015509737	[107]	[34]	4	hSpCas9	negative selection	468182
186720150	186720173	3	+	26472758	Raji	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.3944134222763718	[317]	[96]	4	hSpCas9	negative selection	468183
186717556	186717579	3	-	26472758	Raji	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	-0.35627266912542316	[170]	[30]	-3	hSpCas9	negative selection	468184
186725122	186725145	3	-	26472758	K562	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.7003186553334908	[408]	[560]	6	hSpCas9	negative selection	659293
186732526	186732549	3	-	26472758	K562	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	1.035166019685085	[673]	[1165]	8	hSpCas9	negative selection	659294
186717578	186717601	3	+	26472758	K562	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.23121318886717915	[438]	[434]	1	hSpCas9	negative selection	659295
186722443	186722466	3	+	26472758	K562	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.5374143309413115	[412]	[505]	4	hSpCas9	negative selection	659296
186722472	186722495	3	+	26472758	K562	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	-0.1314481743317191	[435]	[335]	-1	hSpCas9	negative selection	659297
186732519	186732542	3	+	26472758	K562	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	0.21152684610907202	[487]	[476]	1	hSpCas9	negative selection	659298
186739403	186739426	3	-	26472758	K562	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	1.102166144708689	[212]	[385]	8	hSpCas9	negative selection	659299
186717614	186717637	3	+	26472758	K562	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	0.3355666157246424	[91]	[97]	2	hSpCas9	negative selection	659300
186720150	186720173	3	+	26472758	K562	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.7109397710900636	[405]	[560]	6	hSpCas9	negative selection	659301
186717556	186717579	3	-	26472758	K562	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	0.13194399840803428	[279]	[258]	1	hSpCas9	negative selection	659302
186725122	186725145	3	-	26627737	DLD1	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.621253757968928	[733]	[268,192,8]	-6	hSpCas9	negative selection	820860
186727332	186727355	3	-	26627737	DLD1	viability	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	0.3455506869424909	[336]	[155,95,145]	3	hSpCas9	negative selection	820861
186732485	186732508	3	+	26627737	DLD1	viability	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	1.9278950069695486	[109]	[113,76,189]	9	hSpCas9	negative selection	820862
186739387	186739410	3	+	26627737	DLD1	viability	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.5560450291745606	[548]	[263,295,205]	5	hSpCas9	negative selection	820863
186741747	186741770	3	+	26627737	DLD1	viability	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	-0.3971841207769734	[943]	[272,213,189]	-4	hSpCas9	negative selection	820864
186743711	186743734	3	+	26627737	DLD1	viability	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	-0.5695482780476261	[736]	[253,91,121]	-5	hSpCas9	negative selection	820865
186725122	186725145	3	-	26627737	GBM cells	viability after 5 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.23175774725223158	[315]	[185,211]	3	hSpCas9	negative selection	903175
186727332	186727355	3	-	26627737	GBM cells	viability after 5 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	0.2310377368789365	[281]	[137,216]	3	hSpCas9	negative selection	903176
186732485	186732508	3	+	26627737	GBM cells	viability after 5 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	0.5216312976022599	[175]	[116,153]	7	hSpCas9	negative selection	903177
186739387	186739410	3	+	26627737	GBM cells	viability after 5 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.8466996704447476	[210]	[211,194]	9	hSpCas9	negative selection	903178
186741747	186741770	3	+	26627737	GBM cells	viability after 5 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.18819118348273234	[571]	[356,341]	3	hSpCas9	negative selection	903179
186743711	186743734	3	+	26627737	GBM cells	viability after 5 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.49930641617644766	[371]	[227,335]	7	hSpCas9	negative selection	903180
186725122	186725145	3	-	26627737	GBM cells	viability after 13 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.12408183795179328	[315]	[241,141]	1	hSpCas9	negative selection	985490
186727332	186727355	3	-	26627737	GBM cells	viability after 13 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	-0.21635280295916312	[281]	[150,115]	-3	hSpCas9	negative selection	985491
186732485	186732508	3	+	26627737	GBM cells	viability after 13 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	0.042352065671719286	[175]	[83,109]	0	hSpCas9	negative selection	985492
186739387	186739410	3	+	26627737	GBM cells	viability after 13 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.6893431264834585	[210]	[161,202]	8	hSpCas9	negative selection	985493
186741747	186741770	3	+	26627737	GBM cells	viability after 13 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.10431537694202442	[571]	[417,264]	1	hSpCas9	negative selection	985494
186743711	186743734	3	+	26627737	GBM cells	viability after 13 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.20881401483590722	[371]	[299,178]	2	hSpCas9	negative selection	985495
186725122	186725145	3	-	26627737	GBM cells	viability after 21 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.17644801984150088	[315]	[181,204]	1	hSpCas9	negative selection	1067805
186727332	186727355	3	-	26627737	GBM cells	viability after 21 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	0.10923691001184446	[281]	[170,159]	1	hSpCas9	negative selection	1067806
186732485	186732508	3	+	26627737	GBM cells	viability after 21 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	0.9312362030497616	[175]	[197,167]	8	hSpCas9	negative selection	1067807
186739387	186739410	3	+	26627737	GBM cells	viability after 21 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	1.0372190932557643	[210]	[240,229]	8	hSpCas9	negative selection	1067808
186741747	186741770	3	+	26627737	GBM cells	viability after 21 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.32505932038051766	[571]	[405,373]	3	hSpCas9	negative selection	1067809
186743711	186743734	3	+	26627737	GBM cells	viability after 21 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.339821605197545	[371]	[260,250]	3	hSpCas9	negative selection	1067810
186725122	186725145	3	-	26627737	RPE1	viability after 9 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.24324463231070503	[1305]	[462,510]	1	hSpCas9	negative selection	1150120
186727332	186727355	3	-	26627737	RPE1	viability after 9 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	1.1891638852100115	[265]	[257,101]	7	hSpCas9	negative selection	1150121
186732485	186732508	3	+	26627737	RPE1	viability after 9 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	0.20686201803405807	[509]	[199,163]	1	hSpCas9	negative selection	1150122
186739387	186739410	3	+	26627737	RPE1	viability after 9 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	-0.1580453722306611	[1031]	[258,328]	-1	hSpCas9	negative selection	1150123
186741747	186741770	3	+	26627737	RPE1	viability after 9 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.8417240967125417	[1052]	[561,627]	5	hSpCas9	negative selection	1150124
186743711	186743734	3	+	26627737	RPE1	viability after 9 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.5907214460036034	[1089]	[347,727]	4	hSpCas9	negative selection	1150125
186725122	186725145	3	-	26627737	RPE1	viability after 12 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.24300898772417512	[1305]	[261,332]	-2	hSpCas9	negative selection	1232435
186727332	186727355	3	-	26627737	RPE1	viability after 12 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	1.0734897329622233	[265]	[180,117]	6	hSpCas9	negative selection	1232436
186732485	186732508	3	+	26627737	RPE1	viability after 12 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	0.6071435155601741	[509]	[232,182]	4	hSpCas9	negative selection	1232437
186739387	186739410	3	+	26627737	RPE1	viability after 12 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.07244832290738967	[1031]	[343,235]	0	hSpCas9	negative selection	1232438
186741747	186741770	3	+	26627737	RPE1	viability after 12 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.7906077540879641	[1052]	[450,529]	5	hSpCas9	negative selection	1232439
186743711	186743734	3	+	26627737	RPE1	viability after 12 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.5239691133847224	[1089]	[423,417]	3	hSpCas9	negative selection	1232440
186725122	186725145	3	-	26627737	RPE1	viability after 15 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.003557863297939501	[1305]	[434,307]	0	hSpCas9	negative selection	1314750
186727332	186727355	3	-	26627737	RPE1	viability after 15 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	1.0857809545706558	[265]	[175,143]	6	hSpCas9	negative selection	1314751
186732485	186732508	3	+	26627737	RPE1	viability after 15 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	0.19614877723956392	[509]	[233,98]	1	hSpCas9	negative selection	1314752
186739387	186739410	3	+	26627737	RPE1	viability after 15 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	-0.5868592824717931	[1031]	[201,186]	-4	hSpCas9	negative selection	1314753
186741747	186741770	3	+	26627737	RPE1	viability after 15 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.6704571653025146	[1052]	[609,342]	4	hSpCas9	negative selection	1314754
186743711	186743734	3	+	26627737	RPE1	viability after 15 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.6647462777631463	[1089]	[527,450]	4	hSpCas9	negative selection	1314755
186725122	186725145	3	-	26627737	RPE1	viability after 18 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.152845759454317	[1305]	[459,318]	1	hSpCas9	negative selection	1397065
186727332	186727355	3	-	26627737	RPE1	viability after 18 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	1.0862664219586586	[265]	[149,154]	6	hSpCas9	negative selection	1397066
186732485	186732508	3	+	26627737	RPE1	viability after 18 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	0.5224942594899048	[509]	[188,206]	3	hSpCas9	negative selection	1397067
186739387	186739410	3	+	26627737	RPE1	viability after 18 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	-0.1711171173178123	[1031]	[213,282]	-1	hSpCas9	negative selection	1397068
186741747	186741770	3	+	26627737	RPE1	viability after 18 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.6775977619194464	[1052]	[396,515]	4	hSpCas9	negative selection	1397069
186743711	186743734	3	+	26627737	RPE1	viability after 18 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.6759709495332518	[1089]	[264,688]	4	hSpCas9	negative selection	1397070
186725122	186725145	3	-	26627737	HeLa	viability after 8 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.5617132038710989	[757]	[224,344,108]	-5	hSpCas9	negative selection	1479380
186727332	186727355	3	-	26627737	HeLa	viability after 8 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	-0.5859292332217205	[419]	[110,101,147]	-5	hSpCas9	negative selection	1479381
186732485	186732508	3	+	26627737	HeLa	viability after 8 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.07546486564542662	[358]	[202,226,34]	0	hSpCas9	negative selection	1479382
186739387	186739410	3	+	26627737	HeLa	viability after 8 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.5804476892723089	[399]	[366,320,125]	5	hSpCas9	negative selection	1479383
186741747	186741770	3	+	26627737	HeLa	viability after 8 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.2554767079823179	[886]	[695,395,349]	2	hSpCas9	negative selection	1479384
186743711	186743734	3	+	26627737	HeLa	viability after 8 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.4209637043630251	[539]	[514,263,215]	4	hSpCas9	negative selection	1479385
186725122	186725145	3	-	26627737	HeLa	viability after 12 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.7587318526567456	[757]	[234,164,158]	-6	hSpCas9	negative selection	1561695
186727332	186727355	3	-	26627737	HeLa	viability after 12 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	-0.1707632780649392	[419]	[114,148,197]	-1	hSpCas9	negative selection	1561696
186732485	186732508	3	+	26627737	HeLa	viability after 12 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.3529756927208946	[358]	[221,45,90]	-3	hSpCas9	negative selection	1561697
186739387	186739410	3	+	26627737	HeLa	viability after 12 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.3957816815624088	[399]	[242,124,294]	3	hSpCas9	negative selection	1561698
186741747	186741770	3	+	26627737	HeLa	viability after 12 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.27043435338131827	[886]	[446,522,347]	2	hSpCas9	negative selection	1561699
186743711	186743734	3	+	26627737	HeLa	viability after 12 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	-0.3367386652599162	[539]	[163,230,128]	-3	hSpCas9	negative selection	1561700
186725122	186725145	3	-	26627737	HeLa	viability after 15 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.5011770968537457	[757]	[150,260,244]	-4	hSpCas9	negative selection	1644010
186727332	186727355	3	-	26627737	HeLa	viability after 15 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	-0.3008694695138372	[419]	[206,87,118]	-3	hSpCas9	negative selection	1644011
186732485	186732508	3	+	26627737	HeLa	viability after 15 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.039507631879196786	[358]	[187,95,141]	0	hSpCas9	negative selection	1644012
186739387	186739410	3	+	26627737	HeLa	viability after 15 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	-0.059769864627512666	[399]	[125,199,141]	0	hSpCas9	negative selection	1644013
186741747	186741770	3	+	26627737	HeLa	viability after 15 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	-0.002631005196306102	[886]	[421,219,444]	0	hSpCas9	negative selection	1644014
186743711	186743734	3	+	26627737	HeLa	viability after 15 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	-0.15350416449796633	[539]	[179,132,286]	-1	hSpCas9	negative selection	1644015
186725122	186725145	3	-	26627737	HeLa	viability after 18 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.4782542346303307	[757]	[104,219,244]	-4	hSpCas9	negative selection	1726325
186727332	186727355	3	-	26627737	HeLa	viability after 18 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	-0.30398987649705417	[419]	[138,71,118]	-3	hSpCas9	negative selection	1726326
186732485	186732508	3	+	26627737	HeLa	viability after 18 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.08364534961991316	[358]	[114,82,141]	0	hSpCas9	negative selection	1726327
186739387	186739410	3	+	26627737	HeLa	viability after 18 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	-0.03634790049371812	[399]	[89,164,141]	0	hSpCas9	negative selection	1726328
186741747	186741770	3	+	26627737	HeLa	viability after 18 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	-0.01353864682388517	[886]	[277,181,444]	0	hSpCas9	negative selection	1726329
186743711	186743734	3	+	26627737	HeLa	viability after 18 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	-0.15079023123288876	[539]	[115,116,286]	-1	hSpCas9	negative selection	1726330
186725122	186725145	3	-	26627737	HCT116	viability after 6 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	1.2265186224322622	[1086]	[910,117]	6	hSpCas9	negative selection	1808640
186727332	186727355	3	-	26627737	HCT116	viability after 6 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	2.319394862349775	[326]	[88,348]	9	hSpCas9	negative selection	1808641
186732485	186732508	3	+	26627737	HCT116	viability after 6 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.08831587691877507	[188]	[74,1]	0	hSpCas9	negative selection	1808642
186739387	186739410	3	+	26627737	HCT116	viability after 6 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	1.9853541133036985	[352]	[347,148]	8	hSpCas9	negative selection	1808643
186741747	186741770	3	+	26627737	HCT116	viability after 6 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.787803664732823	[1334]	[507,281]	4	hSpCas9	negative selection	1808644
186743711	186743734	3	+	26627737	HCT116	viability after 6 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	1.5410823797523197	[820]	[635,231]	7	hSpCas9	negative selection	1808645
186725122	186725145	3	-	26627737	HCT116	viability after 8 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.6569578752695662	[366]	[346,283,325]	6	hSpCas9	negative selection	1890955
186727332	186727355	3	-	26627737	HCT116	viability after 8 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	-0.12194825215034977	[301]	[116,177,162]	-1	hSpCas9	negative selection	1890956
186732485	186732508	3	+	26627737	HCT116	viability after 8 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	0.2757211245609106	[214]	[178,116,134]	3	hSpCas9	negative selection	1890957
186739387	186739410	3	+	26627737	HCT116	viability after 8 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.3357596090292258	[225]	[204,163,103]	3	hSpCas9	negative selection	1890958
186741747	186741770	3	+	26627737	HCT116	viability after 8 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.38803290858031536	[675]	[506,410,543]	4	hSpCas9	negative selection	1890959
186743711	186743734	3	+	26627737	HCT116	viability after 8 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.1844316409552924	[464]	[417,267,190]	2	hSpCas9	negative selection	1890960
186725122	186725145	3	-	26627737	HCT116	viability after 9 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.1883625132108887	[1086]	[318,339]	1	hSpCas9	negative selection	1973270
186727332	186727355	3	-	26627737	HCT116	viability after 9 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	1.3064295943141142	[326]	[430,45]	8	hSpCas9	negative selection	1973271
186732485	186732508	3	+	26627737	HCT116	viability after 9 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.9473460309258188	[188]	[14,34]	-6	hSpCas9	negative selection	1973272
186739387	186739410	3	+	26627737	HCT116	viability after 9 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	1.0169195103670576	[352]	[135,233]	7	hSpCas9	negative selection	1973273
186741747	186741770	3	+	26627737	HCT116	viability after 9 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	-0.26967455024635456	[1334]	[269,315]	-2	hSpCas9	negative selection	1973274
186743711	186743734	3	+	26627737	HCT116	viability after 9 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.3552607981984134	[820]	[261,294]	2	hSpCas9	negative selection	1973275
186725122	186725145	3	-	26627737	HCT116	viability after 12 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.628990300906157	[366]	[362,210,312]	6	hSpCas9	negative selection	2055585
186727332	186727355	3	-	26627737	HCT116	viability after 12 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	-0.21744711406157652	[301]	[144,104,157]	-2	hSpCas9	negative selection	2055586
186732485	186732508	3	+	26627737	HCT116	viability after 12 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.6143681601189372	[214]	[34,80,108]	-6	hSpCas9	negative selection	2055587
186739387	186739410	3	+	26627737	HCT116	viability after 12 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.6170145284652014	[225]	[150,214,183]	6	hSpCas9	negative selection	2055588
186741747	186741770	3	+	26627737	HCT116	viability after 12 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.6362422646714818	[675]	[611,500,536]	6	hSpCas9	negative selection	2055589
186743711	186743734	3	+	26627737	HCT116	viability after 12 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.25044474691968	[464]	[254,363,257]	2	hSpCas9	negative selection	2055590
186725122	186725145	3	-	26627737	HCT116	viability after 15 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.49872165110392025	[366]	[374,245,281]	5	hSpCas9	negative selection	2137900
186727332	186727355	3	-	26627737	HCT116	viability after 15 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	-0.3379719588484191	[301]	[183,150,82]	-4	hSpCas9	negative selection	2137901
186732485	186732508	3	+	26627737	HCT116	viability after 15 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.4823554716212797	[214]	[79,84,98]	-5	hSpCas9	negative selection	2137902
186739387	186739410	3	+	26627737	HCT116	viability after 15 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.3197925621354163	[225]	[189,103,194]	3	hSpCas9	negative selection	2137903
186741747	186741770	3	+	26627737	HCT116	viability after 15 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.5094019332590558	[675]	[693,422,557]	5	hSpCas9	negative selection	2137904
186743711	186743734	3	+	26627737	HCT116	viability after 15 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	-0.009745537216286904	[464]	[267,338,189]	0	hSpCas9	negative selection	2137905
186725122	186725145	3	-	26627737	HCT116	viability after 18 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	1.46520215329051	[366]	[572,426,472]	9	hSpCas9	negative selection	2220215
186727332	186727355	3	-	26627737	HCT116	viability after 18 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	-0.15707774735898927	[301]	[210,87,94]	-1	hSpCas9	negative selection	2220216
186732485	186732508	3	+	26627737	HCT116	viability after 18 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.7447106259092502	[214]	[27,33,128]	-6	hSpCas9	negative selection	2220217
186739387	186739410	3	+	26627737	HCT116	viability after 18 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.5629900060766254	[225]	[127,82,283]	5	hSpCas9	negative selection	2220218
186741747	186741770	3	+	26627737	HCT116	viability after 18 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.5153986946900329	[675]	[455,483,459]	4	hSpCas9	negative selection	2220219
186743711	186743734	3	+	26627737	HCT116	viability after 18 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.2683140794381409	[464]	[272,254,285]	2	hSpCas9	negative selection	2220220
186719495	186719518	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTTGGGAGGCCAAGGCGGGGGG	KNG1	ENSG00000113889	0.09588317305989913	[114,12]	[10,18]	0	dCas9-VP64	positive selection	2411146
186725617	186725640	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCCGCCTCCTGG	KNG1	ENSG00000113889	-0.7325628323231226	[970,485]	[85,105]	-4	dCas9-VP64	positive selection	2435344
186727803	186727826	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGGTGATCCGCCCACCTTGG	KNG1	ENSG00000113889	-1.8266088487663314	[149,166]	[13,3]	-8	dCas9-VP64	positive selection	2465209
186728692	186728715	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCACCACTGCACTCCAGCCAAG	KNG1	ENSG00000113889	3.0347564003538725	[8,6]	[27,0]	8	dCas9-VP64	positive selection	2470744
186719495	186719518	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTTGGGAGGCCAAGGCGGGGGG	KNG1	ENSG00000113889	3.077269363618506	[19,18]	[13,93]	9	dCas9-VP64	positive selection	2506401
186725617	186725640	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCCGCCTCCTGG	KNG1	ENSG00000113889	0.3709996490739482	[598,467]	[394,67]	3	dCas9-VP64	positive selection	2530599
186727803	186727826	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGGTGATCCGCCCACCTTGG	KNG1	ENSG00000113889	0.6108739619638027	[154,293]	[174,51]	4	dCas9-VP64	positive selection	2560464
186728692	186728715	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCACCACTGCACTCCAGCCAAG	KNG1	ENSG00000113889	0.038175304513698105	[60,77]	[26,18]	0	dCas9-VP64	positive selection	2565999
186725122	186725145	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.24586862079759073	[2,2]	[3,2]	5	hSpCas9	positive selection	2998023
186722459	186722482	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTACTGCTCCTCTTCCCCACGG	KNG1	ENSG00000113889	0.19572213534673794	[3,3]	[4,2]	4	hSpCas9	positive selection	2998024
186722445	186722468	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGAATGCACGGCAACCGTGGGG	KNG1	ENSG00000113889	0.2525290636478923	[3,2]	[2,3]	5	hSpCas9	positive selection	2998025
186722473	186722496	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.22583496858824362	[3,4]	[2,5]	5	hSpCas9	positive selection	2998026
186725122	186725145	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.35340713611542923	[2,2]	[2,2]	6	hSpCas9	positive selection	3065881
186722459	186722482	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTACTGCTCCTCTTCCCCACGG	KNG1	ENSG00000113889	-0.19928103804246056	[3,3]	[3,0]	-3	hSpCas9	positive selection	3065882
186722445	186722468	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGAATGCACGGCAACCGTGGGG	KNG1	ENSG00000113889	0.5644424601605799	[3,3]	[4,2]	8	hSpCas9	positive selection	3065883
186722473	186722496	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	-0.05239020874910414	[3,3]	[3,1]	0	hSpCas9	positive selection	3065884
186731600	186731623		-	24336571	A375	resistance to PLX after 7 days	AATGTCACAGTTCTGTGAGAAGG	KNG1	ENSG00000113889	-0.3881061757876379	[10,9]	[7,7]	-9	hSpCas9	positive selection	3123645
186731608	186731631		+	24336571	A375	resistance to PLX after 7 days	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.0028699886727419077	[33,37]	[34,36]	0	hSpCas9	positive selection	3123646
186720179	186720202		+	24336571	A375	resistance to PLX after 7 days	CTGGCAGGACTGTGAGTACAAGG	KNG1	ENSG00000113889	0.13915721682752635	[23,29]	[29,29]	4	hSpCas9	positive selection	3123647
186720150	186720173		+	24336571	A375	resistance to PLX after 7 days	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.018562273639936233	[15,13]	[14,14]	0	hSpCas9	positive selection	3123648
186731549	186731572		-	24336571	A375	resistance to PLX after 7 days	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.04062060383063493	[74,79]	[78,78]	1	hSpCas9	positive selection	3123649
186720125	186720148		+	24336571	A375	resistance to PLX after 7 days	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	-0.0671445790294134	[46,44]	[42,44]	-2	hSpCas9	positive selection	3123650
186731600	186731623		-	24336571	A375	resistance to PLX after 14 days	AATGTCACAGTTCTGTGAGAAGG	KNG1	ENSG00000113889	-0.6547681677129766	[9,9]	[2,1]	-7	hSpCas9	positive selection	3181438
186731608	186731631		+	24336571	A375	resistance to PLX after 14 days	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.6610557560993972	[39,39]	[10,11]	-7	hSpCas9	positive selection	3181439
186720179	186720202		+	24336571	A375	resistance to PLX after 14 days	CTGGCAGGACTGTGAGTACAAGG	KNG1	ENSG00000113889	0.31301859481848116	[21,41]	[19,16]	3	hSpCas9	positive selection	3181440
186720150	186720173		+	24336571	A375	resistance to PLX after 14 days	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	3.3385580773115073	[12,13]	[46,83]	9	hSpCas9	positive selection	3181441
186731549	186731572		-	24336571	A375	resistance to PLX after 14 days	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.4491379610224975	[87,87]	[28,29]	-5	hSpCas9	positive selection	3181442
186720125	186720148		+	24336571	A375	resistance to PLX after 14 days	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.01121842869616807	[37,42]	[16,20]	0	hSpCas9	positive selection	3181443
186731600	186731623		-	24336571	A375	viability after 7 days	AATGTCACAGTTCTGTGAGAAGG	KNG1	ENSG00000113889	-0.22660986028029975	[12]	[10,9]	-3	hSpCas9	negative selection	3239231
186731608	186731631		+	24336571	A375	viability after 7 days	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.1989840549307964	[42]	[33,37]	-3	hSpCas9	negative selection	3239232
186720179	186720202		+	24336571	A375	viability after 7 days	CTGGCAGGACTGTGAGTACAAGG	KNG1	ENSG00000113889	0.4058827325137171	[20]	[23,29]	6	hSpCas9	negative selection	3239233
186720150	186720173		+	24336571	A375	viability after 7 days	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	-0.022977377677978555	[15]	[15,13]	0	hSpCas9	negative selection	3239234
186731549	186731572		-	24336571	A375	viability after 7 days	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.08451133083360185	[85]	[74,79]	-1	hSpCas9	negative selection	3239235
186720125	186720148		+	24336571	A375	viability after 7 days	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.49798493195533333	[33]	[46,44]	7	hSpCas9	negative selection	3239236
186731600	186731623		-	24336571	A375	viability after 14 days	AATGTCACAGTTCTGTGAGAAGG	KNG1	ENSG00000113889	-0.28327577905291673	[12]	[9,9]	-3	hSpCas9	negative selection	3297024
186731608	186731631		+	24336571	A375	viability after 14 days	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.024975144872049437	[42]	[39,39]	0	hSpCas9	negative selection	3297025
186720179	186720202		+	24336571	A375	viability after 14 days	CTGGCAGGACTGTGAGTACAAGG	KNG1	ENSG00000113889	0.66316616907213	[20]	[21,41]	8	hSpCas9	negative selection	3297026
186720150	186720173		+	24336571	A375	viability after 14 days	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	-0.16081737672699192	[15]	[12,13]	-2	hSpCas9	negative selection	3297027
186731549	186731572		-	24336571	A375	viability after 14 days	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.11823616962593686	[85]	[87,87]	1	hSpCas9	negative selection	3297028
186720125	186720148		+	24336571	A375	viability after 14 days	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.3346422892910803	[33]	[37,42]	4	hSpCas9	negative selection	3297029
186720125	186720148	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	-0.9714924790500457	[299,299]	[0,0]	-6	hSpCas9	positive selection	3376171
186731549	186731572	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.6222570381669483	[470,470]	[1,1]	-4	hSpCas9	positive selection	3376172
186731608	186731631	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	1.0874012100035229	[71,71]	[0,0]	5	hSpCas9	positive selection	3376173
186725122	186725145	3	-	26780180	HT29	viability (Avana library 4 designs)	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	3.15904525619604	[]	[]	8	hSpCas9	negative selection	3435469
186722459	186722482	3	-	26780180	HT29	viability (Avana library 4 designs)	CGTACTGCTCCTCTTCCCCACGG	KNG1	ENSG00000113889	1.33550987351405	[]	[]	5	hSpCas9	negative selection	3435470
186722444	186722467	3	+	26780180	HT29	viability (Avana library 4 designs)	GAGAATGCACGGCAACCGTGGGG	KNG1	ENSG00000113889	0.878331141990135	[]	[]	3	hSpCas9	negative selection	3435471
186722472	186722495	3	+	26780180	HT29	viability (Avana library 4 designs)	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	1.72321895332069	[]	[]	6	hSpCas9	negative selection	3435472
186722472	186722495	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	4.40264617929591	[]	[]	7	hSpCas9	negative selection	3523057
186722459	186722482	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGTACTGCTCCTCTTCCCCACGG	KNG1	ENSG00000113889	-2.41185179483678	[]	[]	-3	hSpCas9	negative selection	3523058
186725122	186725145	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	1.41031482036536	[]	[]	2	hSpCas9	negative selection	3523059
186722444	186722467	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGAATGCACGGCAACCGTGGGG	KNG1	ENSG00000113889	2.91758440539749	[]	[]	4	hSpCas9	negative selection	3523060
186722433	186722456	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTAGGCCACTGGAGAATGCACGG	KNG1	ENSG00000113889	3.35904564800253	[]	[]	5	hSpCas9	negative selection	3523061
186720128	186720151	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCAAGTACGAAATCAAGGAGG	KNG1	ENSG00000113889	-4.46869272888343	[]	[]	-5	hSpCas9	negative selection	3523062
186722472	186722495	3	+	26780180	A375	viability (Avana lentiGuide)	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	-0.625325877076077	[]	[]	-1	hSpCas9	negative selection	3631716
186722459	186722482	3	-	26780180	A375	viability (Avana lentiGuide)	CGTACTGCTCCTCTTCCCCACGG	KNG1	ENSG00000113889	0.502093635554644	[]	[]	0	hSpCas9	negative selection	3631717
186725122	186725145	3	-	26780180	A375	viability (Avana lentiGuide)	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-5.57456916865085	[]	[]	-8	hSpCas9	negative selection	3631718
186722444	186722467	3	+	26780180	A375	viability (Avana lentiGuide)	GAGAATGCACGGCAACCGTGGGG	KNG1	ENSG00000113889	6.95939825980536	[]	[]	5	hSpCas9	negative selection	3631719
186722433	186722456	3	+	26780180	A375	viability (Avana lentiGuide)	TTAGGCCACTGGAGAATGCACGG	KNG1	ENSG00000113889	-3.85005304421687	[]	[]	-6	hSpCas9	negative selection	3631720
186720128	186720151	3	+	26780180	A375	viability (Avana lentiGuide)	CTTCAAGTACGAAATCAAGGAGG	KNG1	ENSG00000113889	-0.0577607480507325	[]	[]	0	hSpCas9	negative selection	3631721
186722472	186722495	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.25116180115590264	[5]	[6,6]	7	hSpCas9	positive selection	3740375
186722459	186722482	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTACTGCTCCTCTTCCCCACGG	KNG1	ENSG00000113889	-0.003788268596788699	[4]	[5,4]	0	hSpCas9	positive selection	3740376
186725122	186725145	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.502673261042546	[4]	[3,2]	-6	hSpCas9	positive selection	3740377
186722444	186722467	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGAATGCACGGCAACCGTGGGG	KNG1	ENSG00000113889	0.2965008864225995	[4]	[5,6]	8	hSpCas9	positive selection	3740378
186722433	186722456	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAGGCCACTGGAGAATGCACGG	KNG1	ENSG00000113889	0.3378507066801557	[5]	[7,6]	8	hSpCas9	positive selection	3740379
186720128	186720151	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCAAGTACGAAATCAAGGAGG	KNG1	ENSG00000113889	-0.13785257878504426	[5]	[4,4]	-2	hSpCas9	positive selection	3740380
186722472	186722495	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.18485185369175278	[6]	[6,5]	4	hSpCas9	positive selection	3848982
186722459	186722482	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTACTGCTCCTCTTCCCCACGG	KNG1	ENSG00000113889	-0.42364984725991656	[5]	[4,2]	-5	hSpCas9	positive selection	3848983
186725122	186725145	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.022482671850583058	[4]	[4,2]	0	hSpCas9	positive selection	3848984
186722444	186722467	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGAATGCACGGCAACCGTGGGG	KNG1	ENSG00000113889	-0.022877088943107	[4]	[3,3]	0	hSpCas9	positive selection	3848985
186722433	186722456	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAGGCCACTGGAGAATGCACGG	KNG1	ENSG00000113889	0.27378410492402183	[6]	[6,6]	7	hSpCas9	positive selection	3848986
186720128	186720151	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCAAGTACGAAATCAAGGAGG	KNG1	ENSG00000113889	0.1800023959656588	[5]	[5,5]	4	hSpCas9	positive selection	3848987
186732518	186732541	3	+	26780180	A375	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.860215171828586	[]	[]	3	hSpCas9	negative selection	3955066
186731608	186731631	3	+	26780180	A375	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	1.10951556413516	[]	[]	5	hSpCas9	negative selection	3955067
186732522	186732545	3	-	26780180	A375	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.225944319646428	[]	[]	0	hSpCas9	negative selection	3955068
186720127	186720150	3	-	26780180	A375	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.505773671740729	[]	[]	1	hSpCas9	negative selection	3955069
186731549	186731572	3	-	26780180	A375	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	1.18034447869018	[]	[]	6	hSpCas9	negative selection	3955070
186720125	186720148	3	+	26780180	A375	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	-0.230281247669988	[]	[]	-6	hSpCas9	negative selection	3955071
186732518	186732541	3	+	26780180	HT29	viability (GeCKOv2 library)	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.446230775763082	[]	[]	1	hSpCas9	negative selection	4063032
186731608	186731631	3	+	26780180	HT29	viability (GeCKOv2 library)	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	1.17815516781536	[]	[]	6	hSpCas9	negative selection	4063033
186732522	186732545	3	-	26780180	HT29	viability (GeCKOv2 library)	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.462244439432476	[]	[]	1	hSpCas9	negative selection	4063034
186720127	186720150	3	-	26780180	HT29	viability (GeCKOv2 library)	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.0538720360239543	[]	[]	0	hSpCas9	negative selection	4063035
186731549	186731572	3	-	26780180	HT29	viability (GeCKOv2 library)	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.871803046262383	[]	[]	3	hSpCas9	negative selection	4063036
186720125	186720148	3	+	26780180	HT29	viability (GeCKOv2 library)	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	-0.32178280362713	[]	[]	-7	hSpCas9	negative selection	4063037
186731600	186731623	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATGTCACAGTTCTGTGAGAAGG	KNG1	ENSG00000113889	-0.5445983318297045	[3]	[1,1]	-9	hSpCas9	positive selection	4147595
186731608	186731631	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.19670459426915782	[4]	[3,3]	5	hSpCas9	positive selection	4147596
186720179	186720202	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGGCAGGACTGTGAGTACAAGG	KNG1	ENSG00000113889	0.27664438004755953	[4]	[3,4]	7	hSpCas9	positive selection	4147597
186720150	186720173	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.5609489677723206	[4]	[2,5]	9	hSpCas9	positive selection	4147598
186731549	186731572	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.20289590165766147	[5]	[3,4]	5	hSpCas9	positive selection	4147599
186720125	186720148	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	-0.004937250870314269	[5]	[2,4]	0	hSpCas9	positive selection	4147600
186731600	186731623	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATGTCACAGTTCTGTGAGAAGG	KNG1	ENSG00000113889	-0.7275818319656662	[3]	[0,0,0,0]	-8	hSpCas9	positive selection	4211617
186731608	186731631	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.8073067031142388	[5]	[2,5,3,3]	5	hSpCas9	positive selection	4211618
186720179	186720202	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGGCAGGACTGTGAGTACAAGG	KNG1	ENSG00000113889	0.02179808728740168	[4]	[1,3,3,0]	0	hSpCas9	positive selection	4211619
186720150	186720173	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	1.2605073500129325	[4]	[4,4,3,4]	9	hSpCas9	positive selection	4211620
186731549	186731572	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.9574773324525664	[6]	[4,5,4,4]	6	hSpCas9	positive selection	4211621
186720125	186720148	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.3418516364598785	[5]	[4,4,4,0]	2	hSpCas9	positive selection	4211622
186732518	186732541	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.4510665632453182	[2]	[2,2]	8	hSpCas9	positive selection	4279017
186732522	186732545	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.18230773242743287	[3]	[3,1]	-4	hSpCas9	positive selection	4279018
186720127	186720150	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.6663035908623244	[3]	[3,4]	9	hSpCas9	positive selection	4279019
186720125	186720148	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.24602471023656536	[3]	[4,2]	5	hSpCas9	positive selection	4343273
186731549	186731572	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.24679120334051802	[4]	[4,3]	5	hSpCas9	positive selection	4343274
186731608	186731631	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.18353003018609587	[1]	[1,1]	3	hSpCas9	positive selection	4343275
186717698	186717720	3	-	27760321	OCIAML3	viability	TATGCGGTACAATACAAACTGG	KNG1	ENSG00000113889	-1.4197826801293685	[28,19]	[0,14]	-8	hSpCas9	negative selection	4412934
186722444	186722466	3	+	27760321	OCIAML3	viability	GAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	-0.7644484989519775	[382,349]	[149,192]	-6	hSpCas9	negative selection	4412935
186722473	186722495	3	+	27760321	OCIAML3	viability	AGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	-0.801618886627117	[481,335]	[203,151]	-6	hSpCas9	negative selection	4412936
186725110	186725132	3	-	27760321	OCIAML3	viability	ACAGCCGAGGCAGTCGTACTGG	KNG1	ENSG00000113889	-0.010169007992738621	[381,294]	[184,359]	0	hSpCas9	negative selection	4412937
186725168	186725190	3	-	27760321	OCIAML3	viability	GAATGCCGTGTCTCAGAATGGG	KNG1	ENSG00000113889	-0.18802622679789588	[333,305]	[170,282]	-2	hSpCas9	negative selection	4412938
186717698	186717720	3	-	27760321	OCIAML2	viability	TATGCGGTACAATACAAACTGG	KNG1	ENSG00000113889	-0.39807985990080663	[28,19]	[13,15]	-5	hSpCas9	negative selection	4496397
186722444	186722466	3	+	27760321	OCIAML2	viability	GAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	-0.3183159449326194	[382,349]	[241,231]	-4	hSpCas9	negative selection	4496398
186722473	186722495	3	+	27760321	OCIAML2	viability	AGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.016861273387057715	[481,335]	[254,430]	0	hSpCas9	negative selection	4496399
186725110	186725132	3	-	27760321	OCIAML2	viability	ACAGCCGAGGCAGTCGTACTGG	KNG1	ENSG00000113889	0.2718442811645198	[381,294]	[338,313]	3	hSpCas9	negative selection	4496400
186725168	186725190	3	-	27760321	OCIAML2	viability	GAATGCCGTGTCTCAGAATGGG	KNG1	ENSG00000113889	-0.054258434227764496	[333,305]	[193,321]	0	hSpCas9	negative selection	4496401
186717698	186717720	3	-	27760321	MV411	viability	TATGCGGTACAATACAAACTGG	KNG1	ENSG00000113889	-3.997916211477075	[28,19]	[0,0]	-9	hSpCas9	negative selection	4579860
186722444	186722466	3	+	27760321	MV411	viability	GAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	1.2885361070643744	[382,349]	[56,1391]	8	hSpCas9	negative selection	4579861
186722473	186722495	3	+	27760321	MV411	viability	AGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	1.0036456995572918	[481,335]	[550,510]	7	hSpCas9	negative selection	4579862
186725110	186725132	3	-	27760321	MV411	viability	ACAGCCGAGGCAGTCGTACTGG	KNG1	ENSG00000113889	-0.5287490910630928	[381,294]	[44,316]	-4	hSpCas9	negative selection	4579863
186725168	186725190	3	-	27760321	MV411	viability	GAATGCCGTGTCTCAGAATGGG	KNG1	ENSG00000113889	1.6115865925731119	[333,305]	[772,452]	9	hSpCas9	negative selection	4579864
186717698	186717720	3	-	27760321	HL60	viability	TATGCGGTACAATACAAACTGG	KNG1	ENSG00000113889	0.15172329907627802	[28,19]	[20,22]	1	hSpCas9	negative selection	4663323
186722444	186722466	3	+	27760321	HL60	viability	GAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.2080346266933175	[382,349]	[417,268]	2	hSpCas9	negative selection	4663324
186722473	186722495	3	+	27760321	HL60	viability	AGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.261533613869127	[481,335]	[526,256]	3	hSpCas9	negative selection	4663325
186725110	186725132	3	-	27760321	HL60	viability	ACAGCCGAGGCAGTCGTACTGG	KNG1	ENSG00000113889	-0.07428254594766653	[381,294]	[317,199]	-1	hSpCas9	negative selection	4663326
186725168	186725190	3	-	27760321	HL60	viability	GAATGCCGTGTCTCAGAATGGG	KNG1	ENSG00000113889	-0.049309627110419696	[333,305]	[286,215]	0	hSpCas9	negative selection	4663327
186717698	186717720	3	-	27760321	HT1080	viability	TATGCGGTACAATACAAACTGG	KNG1	ENSG00000113889	0.8584406827840985	[19,15]	[23,0]	4	hSpCas9	negative selection	4746786
186722444	186722466	3	+	27760321	HT1080	viability	GAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.7471776991048803	[349,272]	[150,270]	4	hSpCas9	negative selection	4746787
186722473	186722495	3	+	27760321	HT1080	viability	AGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	1.0814947414679354	[335,261]	[189,319]	6	hSpCas9	negative selection	4746788
186725110	186725132	3	-	27760321	HT1080	viability	ACAGCCGAGGCAGTCGTACTGG	KNG1	ENSG00000113889	-0.3887892539248177	[294,229]	[76,82]	-2	hSpCas9	negative selection	4746789
186725168	186725190	3	-	27760321	HT1080	viability	GAATGCCGTGTCTCAGAATGGG	KNG1	ENSG00000113889	-0.9828313325890183	[305,238]	[63,44]	-4	hSpCas9	negative selection	4746790
186717698	186717720	3	-	27760321	HT29	viability after 7 days	TATGCGGTACAATACAAACTGG	KNG1	ENSG00000113889	-0.13328716050201717	[19,15]	[4,0,53]	-2	hSpCas9	negative selection	4830249
186722444	186722466	3	+	27760321	HT29	viability after 7 days	GAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	-0.08965467732174895	[349,272]	[368,398,359]	-1	hSpCas9	negative selection	4830250
186722473	186722495	3	+	27760321	HT29	viability after 7 days	AGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.45874863773328817	[335,261]	[586,523,482]	7	hSpCas9	negative selection	4830251
186725110	186725132	3	-	27760321	HT29	viability after 7 days	ACAGCCGAGGCAGTCGTACTGG	KNG1	ENSG00000113889	0.5728894418340988	[294,229]	[587,664,271]	8	hSpCas9	negative selection	4830252
186725168	186725190	3	-	27760321	HT29	viability after 7 days	GAATGCCGTGTCTCAGAATGGG	KNG1	ENSG00000113889	-0.0419297854949488	[305,238]	[370,189,459]	0	hSpCas9	negative selection	4830253
186717698	186717720	3	-	27760321	HT29	viability after 25 days	TATGCGGTACAATACAAACTGG	KNG1	ENSG00000113889	0.21953184273258497	[19,15]	[53,0,13]	2	hSpCas9	negative selection	4913712
186722444	186722466	3	+	27760321	HT29	viability after 25 days	GAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.3465535428824311	[349,272]	[395,604,348]	3	hSpCas9	negative selection	4913713
186722473	186722495	3	+	27760321	HT29	viability after 25 days	AGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.22928825567539135	[335,261]	[323,298,603]	2	hSpCas9	negative selection	4913714
186725110	186725132	3	-	27760321	HT29	viability after 25 days	ACAGCCGAGGCAGTCGTACTGG	KNG1	ENSG00000113889	0.45031795661801666	[294,229]	[289,454,500]	5	hSpCas9	negative selection	4913715
186725168	186725190	3	-	27760321	HT29	viability after 25 days	GAATGCCGTGTCTCAGAATGGG	KNG1	ENSG00000113889	-0.0001572481462533415	[305,238]	[312,193,439]	0	hSpCas9	negative selection	4913716
186717698	186717720	3	-	27760321	HT29	viability after 22 days	TATGCGGTACAATACAAACTGG	KNG1	ENSG00000113889	0.03229003838073208	[19,15]	[51,0,9]	0	hSpCas9	negative selection	4997175
186722444	186722466	3	+	27760321	HT29	viability after 22 days	GAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.12693547118169765	[349,272]	[330,384,465]	1	hSpCas9	negative selection	4997176
186722473	186722495	3	+	27760321	HT29	viability after 22 days	AGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.23958353444853892	[335,261]	[419,489,312]	2	hSpCas9	negative selection	4997177
186725110	186725132	3	-	27760321	HT29	viability after 22 days	ACAGCCGAGGCAGTCGTACTGG	KNG1	ENSG00000113889	0.2892492831523864	[294,229]	[338,431,341]	3	hSpCas9	negative selection	4997178
186725168	186725190	3	-	27760321	HT29	viability after 22 days	GAATGCCGTGTCTCAGAATGGG	KNG1	ENSG00000113889	-0.16259561572530062	[305,238]	[258,301,283]	-2	hSpCas9	negative selection	4997179
186717698	186717720	3	-	27760321	HT29	viability after 19 days	TATGCGGTACAATACAAACTGG	KNG1	ENSG00000113889	0.48092828751968053	[19,15]	[91,0,0]	5	hSpCas9	negative selection	5080638
186722444	186722466	3	+	27760321	HT29	viability after 19 days	GAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.18361571857467934	[349,272]	[363,540,307]	1	hSpCas9	negative selection	5080639
186722473	186722495	3	+	27760321	HT29	viability after 19 days	AGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.4028972997975405	[335,261]	[588,400,382]	4	hSpCas9	negative selection	5080640
186725110	186725132	3	-	27760321	HT29	viability after 19 days	ACAGCCGAGGCAGTCGTACTGG	KNG1	ENSG00000113889	0.4156484840353948	[294,229]	[143,624,404]	4	hSpCas9	negative selection	5080641
186725168	186725190	3	-	27760321	HT29	viability after 19 days	GAATGCCGTGTCTCAGAATGGG	KNG1	ENSG00000113889	-0.3229936797739927	[305,238]	[414,270,84]	-3	hSpCas9	negative selection	5080642
186717698	186717720	3	-	27760321	HT29	viability after 16 days	TATGCGGTACAATACAAACTGG	KNG1	ENSG00000113889	-0.3544239153980717	[19,15]	[39,0,8]	-4	hSpCas9	negative selection	5164101
186722444	186722466	3	+	27760321	HT29	viability after 16 days	GAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.21706761976066527	[349,272]	[435,446,333]	2	hSpCas9	negative selection	5164102
186722473	186722495	3	+	27760321	HT29	viability after 16 days	AGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.1655696034742351	[335,261]	[297,420,397]	1	hSpCas9	negative selection	5164103
186725110	186725132	3	-	27760321	HT29	viability after 16 days	ACAGCCGAGGCAGTCGTACTGG	KNG1	ENSG00000113889	0.24971279293965654	[294,229]	[296,444,297]	2	hSpCas9	negative selection	5164104
186725168	186725190	3	-	27760321	HT29	viability after 16 days	GAATGCCGTGTCTCAGAATGGG	KNG1	ENSG00000113889	-0.030400744397161505	[305,238]	[463,266,180]	0	hSpCas9	negative selection	5164105
186717698	186717720	3	-	27760321	HT29	viability after 13 days	TATGCGGTACAATACAAACTGG	KNG1	ENSG00000113889	-0.23744800933524335	[19,15]	[48,0,3]	-3	hSpCas9	negative selection	5247564
186722444	186722466	3	+	27760321	HT29	viability after 13 days	GAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	-0.042860983422187554	[349,272]	[328,400,323]	0	hSpCas9	negative selection	5247565
186722473	186722495	3	+	27760321	HT29	viability after 13 days	AGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.21005434653004204	[335,261]	[476,522,214]	2	hSpCas9	negative selection	5247566
186725110	186725132	3	-	27760321	HT29	viability after 13 days	ACAGCCGAGGCAGTCGTACTGG	KNG1	ENSG00000113889	0.38484594443237224	[294,229]	[406,375,408]	5	hSpCas9	negative selection	5247567
186725168	186725190	3	-	27760321	HT29	viability after 13 days	GAATGCCGTGTCTCAGAATGGG	KNG1	ENSG00000113889	0.26709241187541277	[305,238]	[263,419,452]	3	hSpCas9	negative selection	5247568
186717698	186717720	3	-	27760321	HT29	viability after 10 days	TATGCGGTACAATACAAACTGG	KNG1	ENSG00000113889	-0.6832640645175516	[19,15]	[2,37,1]	-7	hSpCas9	negative selection	5331027
186722444	186722466	3	+	27760321	HT29	viability after 10 days	GAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.26366495174069443	[349,272]	[514,392,489]	3	hSpCas9	negative selection	5331028
186722473	186722495	3	+	27760321	HT29	viability after 10 days	AGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.3944213228859452	[335,261]	[435,656,385]	5	hSpCas9	negative selection	5331029
186725110	186725132	3	-	27760321	HT29	viability after 10 days	ACAGCCGAGGCAGTCGTACTGG	KNG1	ENSG00000113889	0.616652744332439	[294,229]	[383,606,518]	8	hSpCas9	negative selection	5331030
186725168	186725190	3	-	27760321	HT29	viability after 10 days	GAATGCCGTGTCTCAGAATGGG	KNG1	ENSG00000113889	0.4356741261872769	[305,238]	[349,458,568]	6	hSpCas9	negative selection	5331031
186717698	186717720	3	-	27760321	MOLM13	viability	TATGCGGTACAATACAAACTGG	KNG1	ENSG00000113889	-0.8727148352916023	[28,19]	[7,6]	-5	hSpCas9	negative selection	5414490
186722444	186722466	3	+	27760321	MOLM13	viability	GAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	-2.345422802263065	[382,349]	[71,13]	-8	hSpCas9	negative selection	5414491
186722473	186722495	3	+	27760321	MOLM13	viability	AGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.43435560917696	[481,335]	[317,299]	3	hSpCas9	negative selection	5414492
186725110	186725132	3	-	27760321	MOLM13	viability	ACAGCCGAGGCAGTCGTACTGG	KNG1	ENSG00000113889	0.8851901130852371	[381,294]	[219,460]	6	hSpCas9	negative selection	5414493
186725168	186725190	3	-	27760321	MOLM13	viability	GAATGCCGTGTCTCAGAATGGG	KNG1	ENSG00000113889	-0.23073215275309927	[333,305]	[115,185]	-1	hSpCas9	negative selection	5414494
186717365	186717388	3	-	27661255	K562	viability	GCTAGTTGCCTTGTTCCCAAAGG	KNG1	ENSG00000113889	-0.04962370232017488	[1369,1303]	[1136,943]	-2	dCas9-KRAB	negative selection	5489136
186732518	186732541	3	+	27260156	BXPC3	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.16233082947271127	[292]	[358,336,329,340]	3	hSpCas9	negative selection	5551477
186732522	186732545	3	-	27260156	BXPC3	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.1315750456255707	[570]	[724,566,596,727]	3	hSpCas9	negative selection	5551478
186720127	186720150	3	-	27260156	BXPC3	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.2607701240625478	[529]	[577,623,611,873]	6	hSpCas9	negative selection	5551479
186720125	186720148	3	+	27260156	BXPC3	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.3141532782034462	[829]	[1154,964,1091,1096]	6	hSpCas9	negative selection	5615733
186731549	186731572	3	-	27260156	BXPC3	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.0640640340465346	[1025]	[1161,925,926,1077]	-1	hSpCas9	negative selection	5615734
186731608	186731631	3	+	27260156	BXPC3	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.06155305136472511	[161]	[187,122,172,163]	-1	hSpCas9	negative selection	5615735
186732518	186732541	3	+	27260156	A673	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.3766509793309553	[292]	[516,457,453,400]	8	hSpCas9	negative selection	5672728
186732522	186732545	3	-	27260156	A673	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.1582209596175551	[570]	[826,807,690,737]	4	hSpCas9	negative selection	5672729
186720127	186720150	3	-	27260156	A673	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.2979203394333572	[529]	[814,717,831,766]	7	hSpCas9	negative selection	5672730
186720125	186720148	3	+	27260156	A673	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.2502312999532952	[829]	[1136,1125,1272,1198]	6	hSpCas9	negative selection	5736984
186731549	186731572	3	-	27260156	A673	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.10719541667852361	[1025]	[1318,1121,1135,1008]	-3	hSpCas9	negative selection	5736985
186731608	186731631	3	+	27260156	A673	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.1286637290418482	[161]	[248,134,215,258]	3	hSpCas9	negative selection	5736986
186732518	186732541	3	+	27260156	A375	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.6803700944181909	[292]	[473,497,487,704]	8	hSpCas9	negative selection	5793979
186732522	186732545	3	-	27260156	A375	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.08936738603891808	[570]	[682,886,634,367]	-1	hSpCas9	negative selection	5793980
186720127	186720150	3	-	27260156	A375	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.5075292223178105	[529]	[939,1145,808,682]	7	hSpCas9	negative selection	5793981
186720125	186720148	3	+	27260156	A375	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.5197886204496096	[829]	[1457,1889,1077,1218]	7	hSpCas9	negative selection	5858235
186731549	186731572	3	-	27260156	A375	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.04731000807459096	[1025]	[1472,1236,1140,1113]	0	hSpCas9	negative selection	5858236
186731608	186731631	3	+	27260156	A375	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.12699908554017392	[161]	[171,131,349,165]	1	hSpCas9	negative selection	5858237
186732518	186732541	3	+	27260156	COLO741	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.2737030740632154	[292]	[396,486,466]	6	hSpCas9	negative selection	5915230
186732522	186732545	3	-	27260156	COLO741	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.04847515122993423	[570]	[770,790,704]	1	hSpCas9	negative selection	5915231
186720127	186720150	3	-	27260156	COLO741	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.31319868129829886	[529]	[889,860,779]	6	hSpCas9	negative selection	5915232
186720125	186720148	3	+	27260156	COLO741	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.270274932434998	[829]	[1467,1147,1236]	5	hSpCas9	negative selection	5979486
186731549	186731572	3	-	27260156	COLO741	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.02477208155178734	[1025]	[1485,1114,1278]	0	hSpCas9	negative selection	5979487
186731608	186731631	3	+	27260156	COLO741	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.02595917452331098	[161]	[204,308,123]	0	hSpCas9	negative selection	5979488
186732518	186732541	3	+	27260156	CAL120	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.6001764482622803	[292]	[820,477,401]	8	hSpCas9	negative selection	6036481
186732522	186732545	3	-	27260156	CAL120	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.264592612233538	[570]	[636,493,648]	-4	hSpCas9	negative selection	6036482
186720127	186720150	3	-	27260156	CAL120	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.3355405919627403	[529]	[1165,629,751]	5	hSpCas9	negative selection	6036483
186720125	186720148	3	+	27260156	CAL120	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.33762997127190375	[829]	[1810,1036,1145]	5	hSpCas9	negative selection	6100737
186731549	186731572	3	-	27260156	CAL120	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.08626129616003864	[1025]	[1524,1323,813]	-1	hSpCas9	negative selection	6100738
186731608	186731631	3	+	27260156	CAL120	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.18669842043126916	[161]	[144,122,256]	-3	hSpCas9	negative selection	6100739
186732518	186732541	3	+	27260156	CADOES1	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.10348878156089991	[292]	[230,301,351,285]	1	hSpCas9	negative selection	6157732
186732522	186732545	3	-	27260156	CADOES1	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.1355300419253877	[570]	[418,563,597,347]	-2	hSpCas9	negative selection	6157733
186720127	186720150	3	-	27260156	CADOES1	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.20614767329062883	[529]	[578,604,512,577]	3	hSpCas9	negative selection	6157734
186720125	186720148	3	+	27260156	CADOES1	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.4531311722057978	[829]	[978,1010,1034,1207]	7	hSpCas9	negative selection	6221988
186731549	186731572	3	-	27260156	CADOES1	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.05874397880991733	[1025]	[1034,909,939,773]	-1	hSpCas9	negative selection	6221989
186731608	186731631	3	+	27260156	CADOES1	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.30267692680277847	[161]	[236,209,168,124]	5	hSpCas9	negative selection	6221990
186732518	186732541	3	+	27260156	EWS502	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.1985643140584163	[292]	[437,366,302,299]	3	hSpCas9	negative selection	6278983
186732522	186732545	3	-	27260156	EWS502	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.1557220757099163	[570]	[596,618,460,476]	-3	hSpCas9	negative selection	6278984
186720127	186720150	3	-	27260156	EWS502	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.5474218768733754	[529]	[721,898,726,946]	8	hSpCas9	negative selection	6278985
186720125	186720148	3	+	27260156	EWS502	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.35836319536886796	[829]	[1090,1301,798,1317]	6	hSpCas9	negative selection	6343239
186731549	186731572	3	-	27260156	EWS502	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.07110009838915232	[1025]	[1143,1040,952,976]	-1	hSpCas9	negative selection	6343240
186731608	186731631	3	+	27260156	EWS502	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.14446782424363436	[161]	[104,247,259,150]	2	hSpCas9	negative selection	6343241
186732518	186732541	3	+	27260156	EW8	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.1441456028000644	[292]	[295,300,225,235]	2	hSpCas9	negative selection	6400234
186732522	186732545	3	-	27260156	EW8	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.03933029488880779	[570]	[545,436,387,551]	0	hSpCas9	negative selection	6400235
186720127	186720150	3	-	27260156	EW8	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.42426955932179305	[529]	[860,598,390,515]	7	hSpCas9	negative selection	6400236
186720125	186720148	3	+	27260156	EW8	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.18170880742974993	[829]	[881,599,718,867]	3	hSpCas9	negative selection	6464490
186731549	186731572	3	-	27260156	EW8	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.010943869099714343	[1025]	[1020,647,759,900]	0	hSpCas9	negative selection	6464491
186731608	186731631	3	+	27260156	EW8	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.4784690971575287	[161]	[283,242,98,130]	8	hSpCas9	negative selection	6464492
186732518	186732541	3	+	27260156	CORL105	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.6738463520845207	[292]	[298,584,793,539]	9	hSpCas9	negative selection	6521485
186732522	186732545	3	-	27260156	CORL105	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.17611166458202532	[570]	[767,662,894,718]	3	hSpCas9	negative selection	6521486
186720127	186720150	3	-	27260156	CORL105	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.22964381843945553	[529]	[682,857,751,616]	4	hSpCas9	negative selection	6521487
186720125	186720148	3	+	27260156	CORL105	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.27637845625609847	[829]	[1128,1146,1285,1160]	5	hSpCas9	negative selection	6585741
186731549	186731572	3	-	27260156	CORL105	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.008017452698956262	[1025]	[1131,1283,1327,1050]	0	hSpCas9	negative selection	6585742
186731608	186731631	3	+	27260156	CORL105	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.39390481704202496	[161]	[243,225,218,302]	7	hSpCas9	negative selection	6585743
186732518	186732541	3	+	27260156	HS294T	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.4970809899331684	[292]	[124,167,144,212]	6	hSpCas9	negative selection	6642736
186732522	186732545	3	-	27260156	HS294T	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.6301250530564613	[570]	[380,235,323,440]	7	hSpCas9	negative selection	6642737
186720127	186720150	3	-	27260156	HS294T	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	-0.13279873360776437	[529]	[135,185,242,186]	-2	hSpCas9	negative selection	6642738
186720125	186720148	3	+	27260156	HS294T	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	-0.017943625216760184	[829]	[265,337,369,292]	0	hSpCas9	negative selection	6706992
186731549	186731572	3	-	27260156	HS294T	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.16126371510514115	[1025]	[313,421,330,351]	-2	hSpCas9	negative selection	6706993
186731608	186731631	3	+	27260156	HS294T	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.3221125114864809	[161]	[86,19,48,39]	-4	hSpCas9	negative selection	6706994
186732518	186732541	3	+	27260156	HCC44	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.314741031799587	[292]	[355,352,417,518]	5	hSpCas9	negative selection	6763987
186732522	186732545	3	-	27260156	HCC44	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.03762168621254014	[570]	[441,673,727,659]	0	hSpCas9	negative selection	6763988
186720127	186720150	3	-	27260156	HCC44	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	-0.00878124167023639	[529]	[785,498,662,476]	0	hSpCas9	negative selection	6763989
186720125	186720148	3	+	27260156	HCC44	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.2707700993285238	[829]	[1182,846,1461,1130]	4	hSpCas9	negative selection	6828243
186731549	186731572	3	-	27260156	HCC44	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.14129017032531377	[1025]	[1264,1215,1465,1203]	2	hSpCas9	negative selection	6828244
186731608	186731631	3	+	27260156	HCC44	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.14212424009367353	[161]	[260,137,191,227]	2	hSpCas9	negative selection	6828245
186732518	186732541	3	+	27260156	G402	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.44968013437802873	[292]	[468,520,782,191]	5	hSpCas9	negative selection	6885238
186732522	186732545	3	-	27260156	G402	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.019141208152803124	[570]	[496,785,978,541]	0	hSpCas9	negative selection	6885239
186720127	186720150	3	-	27260156	G402	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.48165652779058893	[529]	[1050,980,688,912]	6	hSpCas9	negative selection	6885240
186720125	186720148	3	+	27260156	G402	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.5070829980356715	[829]	[1532,1547,1769,944]	6	hSpCas9	negative selection	6949494
186731549	186731572	3	-	27260156	G402	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.09240338047604024	[1025]	[944,1105,1238,1943]	1	hSpCas9	negative selection	6949495
186731608	186731631	3	+	27260156	G402	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.4788438224479068	[161]	[196,631,42,239]	6	hSpCas9	negative selection	6949496
186732518	186732541	3	+	27260156	L33	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.5942994279939225	[292]	[289,190,320,505]	9	hSpCas9	negative selection	7006489
186732522	186732545	3	-	27260156	L33	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.24297193205489903	[570]	[639,312,412,642]	5	hSpCas9	negative selection	7006490
186720127	186720150	3	-	27260156	L33	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	-0.09032950998275859	[529]	[516,195,348,440]	-2	hSpCas9	negative selection	7006491
186720125	186720148	3	+	27260156	L33	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.055724750940681966	[829]	[814,322,629,846]	1	hSpCas9	negative selection	7070745
186731549	186731572	3	-	27260156	L33	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.08560224761246227	[1025]	[890,391,636,1007]	-2	hSpCas9	negative selection	7070746
186731608	186731631	3	+	27260156	L33	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.7073937704825775	[161]	[95,41,43,127]	-9	hSpCas9	negative selection	7070747
186732518	186732541	3	+	27260156	K562	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.6666263641821469	[292]	[593,460,268,349]	8	hSpCas9	negative selection	7127740
186732522	186732545	3	-	27260156	K562	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.05214321147512874	[570]	[407,475,774,307]	0	hSpCas9	negative selection	7127741
186720127	186720150	3	-	27260156	K562	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.19567142588140057	[529]	[642,528,634,372]	2	hSpCas9	negative selection	7127742
186720125	186720148	3	+	27260156	K562	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.3589269209485484	[829]	[764,1254,810,944]	4	hSpCas9	negative selection	7191996
186731549	186731572	3	-	27260156	K562	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.25426189646007913	[1025]	[999,1150,1252,947]	3	hSpCas9	negative selection	7191997
186731608	186731631	3	+	27260156	K562	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.16745702099281656	[161]	[134,298,52,43]	-2	hSpCas9	negative selection	7191998
186732518	186732541	3	+	27260156	HT29	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.31545434676296946	[292]	[437,570,343,428]	6	hSpCas9	negative selection	7248991
186732522	186732545	3	-	27260156	HT29	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.25649091222669135	[570]	[713,968,1018,635]	5	hSpCas9	negative selection	7248992
186720127	186720150	3	-	27260156	HT29	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.21826689686933032	[529]	[796,852,864,518]	4	hSpCas9	negative selection	7248993
186720125	186720148	3	+	27260156	HT29	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.412138409532127	[829]	[1471,1576,1038,1306]	7	hSpCas9	negative selection	7313247
186731549	186731572	3	-	27260156	HT29	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.04096700651730689	[1025]	[1402,1355,1305,1096]	0	hSpCas9	negative selection	7313248
186731608	186731631	3	+	27260156	HT29	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.45746561413657716	[161]	[277,436,211,178]	8	hSpCas9	negative selection	7313249
186732518	186732541	3	+	27260156	MHHES1	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.15290978834277935	[292]	[500,460,258,282]	3	hSpCas9	negative selection	7370242
186732522	186732545	3	-	27260156	MHHES1	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.2178159067801239	[570]	[737,810,803,649]	4	hSpCas9	negative selection	7370243
186720127	186720150	3	-	27260156	MHHES1	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.24965020408505922	[529]	[852,692,702,611]	4	hSpCas9	negative selection	7370244
186720125	186720148	3	+	27260156	MHHES1	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.4617551687374881	[829]	[1690,1355,1245,959]	7	hSpCas9	negative selection	7434498
186731549	186731572	3	-	27260156	MHHES1	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.12078631243560944	[1025]	[1339,1457,1207,1065]	2	hSpCas9	negative selection	7434499
186731608	186731631	3	+	27260156	MHHES1	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.4623464871213758	[161]	[340,243,191,235]	7	hSpCas9	negative selection	7434500
186732518	186732541	3	+	27260156	MEWO	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.7916488556805403	[292]	[629,384,438]	9	hSpCas9	negative selection	7491493
186732522	186732545	3	-	27260156	MEWO	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.3093333210721991	[570]	[935,621,480]	6	hSpCas9	negative selection	7491494
186720127	186720150	3	-	27260156	MEWO	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.05108031970694918	[529]	[757,383,446]	1	hSpCas9	negative selection	7491495
186720125	186720148	3	+	27260156	MEWO	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.3766772050621163	[829]	[1143,936,969]	7	hSpCas9	negative selection	7555749
186731549	186731572	3	-	27260156	MEWO	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.016620658648332176	[1025]	[1315,863,737]	0	hSpCas9	negative selection	7555750
186731608	186731631	3	+	27260156	MEWO	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.08257075525285007	[161]	[223,105,163]	1	hSpCas9	negative selection	7555751
186732518	186732541	3	+	27260156	LNCAPCLONEFGC	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.4819392391080639	[292]	[295,422,508,272]	7	hSpCas9	negative selection	7612744
186732522	186732545	3	-	27260156	LNCAPCLONEFGC	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.17447745947898868	[570]	[349,514,482,486]	-3	hSpCas9	negative selection	7612745
186720127	186720150	3	-	27260156	LNCAPCLONEFGC	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.41723427036675614	[529]	[612,823,637,476]	6	hSpCas9	negative selection	7612746
186720125	186720148	3	+	27260156	LNCAPCLONEFGC	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.2725742408860785	[829]	[1012,842,1025,769]	4	hSpCas9	negative selection	7677000
186731549	186731572	3	-	27260156	LNCAPCLONEFGC	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.07084973797726635	[1025]	[898,765,1356,953]	1	hSpCas9	negative selection	7677001
186731608	186731631	3	+	27260156	LNCAPCLONEFGC	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.02888617213502709	[161]	[145,90,218,156]	0	hSpCas9	negative selection	7677002
186732518	186732541	3	+	27260156	PANC0327	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	-0.07814481471607104	[292]	[284,263,217,219]	-1	hSpCas9	negative selection	7733995
186732522	186732545	3	-	27260156	PANC0327	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.42272793928274194	[570]	[495,354,299,374]	-6	hSpCas9	negative selection	7733996
186720127	186720150	3	-	27260156	PANC0327	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.2522260254491548	[529]	[617,635,606,376]	4	hSpCas9	negative selection	7733997
186720125	186720148	3	+	27260156	PANC0327	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.5730975984908677	[829]	[844,757,1563,1243]	8	hSpCas9	negative selection	7798251
186731549	186731572	3	-	27260156	PANC0327	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.08303378258939809	[1025]	[908,671,1261,1051]	1	hSpCas9	negative selection	7798252
186731608	186731631	3	+	27260156	PANC0327	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.8253743375922662	[161]	[85,58,52,129]	-8	hSpCas9	negative selection	7798253
186732518	186732541	3	+	27260156	NCIH2009	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.9640576851845502	[292]	[1063,515,871]	9	hSpCas9	negative selection	7855246
186732522	186732545	3	-	27260156	NCIH2009	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.07077129246533287	[570]	[910,930,682]	1	hSpCas9	negative selection	7855247
186720127	186720150	3	-	27260156	NCIH2009	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.2713504698422388	[529]	[895,789,995]	4	hSpCas9	negative selection	7855248
186720125	186720148	3	+	27260156	NCIH2009	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.2714971072821233	[829]	[1540,1333,1350]	4	hSpCas9	negative selection	7919502
186731549	186731572	3	-	27260156	NCIH2009	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.1878421193302542	[1025]	[1564,1317,2004]	2	hSpCas9	negative selection	7919503
186731608	186731631	3	+	27260156	NCIH2009	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.1921350983951029	[161]	[257,244,101]	-3	hSpCas9	negative selection	7919504
186732518	186732541	3	+	27260156	NCIH1373	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.8476258389695474	[292]	[426,519,685,187]	8	hSpCas9	negative selection	7976497
186732522	186732545	3	-	27260156	NCIH1373	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.05505675598660703	[570]	[380,535,726,262]	0	hSpCas9	negative selection	7976498
186720127	186720150	3	-	27260156	NCIH1373	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.4481600505910602	[529]	[1249,698,892,118]	4	hSpCas9	negative selection	7976499
186720125	186720148	3	+	27260156	NCIH1373	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.44579853749424014	[829]	[1318,1210,1106,381]	4	hSpCas9	negative selection	8040753
186731549	186731572	3	-	27260156	NCIH1373	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.024474140435046143	[1025]	[947,1100,1341,329]	0	hSpCas9	negative selection	8040754
186731608	186731631	3	+	27260156	NCIH1373	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.3327518949507975	[161]	[275,71,115,36]	-3	hSpCas9	negative selection	8040755
186732518	186732541	3	+	27260156	PATU8902	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	-0.18943742479353232	[292]	[210,334,448,418]	-2	hSpCas9	negative selection	8097748
186732522	186732545	3	-	27260156	PATU8902	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.27207862870905547	[570]	[759,484,627,775]	-3	hSpCas9	negative selection	8097749
186720127	186720150	3	-	27260156	PATU8902	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.5496773849527044	[529]	[763,1194,960,1475]	6	hSpCas9	negative selection	8097750
186720125	186720148	3	+	27260156	PATU8902	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.15941816011971732	[829]	[1724,1483,1216,666]	1	hSpCas9	negative selection	8162004
186731549	186731572	3	-	27260156	PATU8902	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.15064148834319813	[1025]	[1324,2004,1145,2027]	1	hSpCas9	negative selection	8162005
186731608	186731631	3	+	27260156	PATU8902	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.8737025592380596	[161]	[118,137,106,132]	-7	hSpCas9	negative selection	8162006
186732518	186732541	3	+	27260156	PANC1	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.2722671564336693	[292]	[350,374,389,136]	4	hSpCas9	negative selection	8218999
186732522	186732545	3	-	27260156	PANC1	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.06260640628313757	[570]	[390,603,686,399]	0	hSpCas9	negative selection	8219000
186720127	186720150	3	-	27260156	PANC1	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.3947815758834277	[529]	[451,734,712,527]	6	hSpCas9	negative selection	8219001
186720125	186720148	3	+	27260156	PANC1	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.2902644559308991	[829]	[709,1047,913,844]	4	hSpCas9	negative selection	8283255
186731549	186731572	3	-	27260156	PANC1	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.24729719579548437	[1025]	[867,902,622,613]	-4	hSpCas9	negative selection	8283256
186731608	186731631	3	+	27260156	PANC1	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.09462960101367668	[161]	[66,197,175,98]	-1	hSpCas9	negative selection	8283257
186732518	186732541	3	+	27260156	PANC0813	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.9402627265284436	[292]	[745,790,631,488]	9	hSpCas9	negative selection	8340250
186732522	186732545	3	-	27260156	PANC0813	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.03576556265119149	[570]	[843,502,552,728]	0	hSpCas9	negative selection	8340251
186720127	186720150	3	-	27260156	PANC0813	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.18914418931742288	[529]	[993,798,437,635]	3	hSpCas9	negative selection	8340252
186720125	186720148	3	+	27260156	PANC0813	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.27486519978889956	[829]	[1164,1421,1054,1077]	4	hSpCas9	negative selection	8404506
186731549	186731572	3	-	27260156	PANC0813	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.21790164579698024	[1025]	[1149,1250,799,955]	-3	hSpCas9	negative selection	8404507
186731608	186731631	3	+	27260156	PANC0813	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.4898910764751174	[161]	[289,64,51,147]	-6	hSpCas9	negative selection	8404508
186732518	186732541	3	+	27260156	RDES	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.5383388046858435	[292]	[443,442,461,626]	8	hSpCas9	negative selection	8461501
186732522	186732545	3	-	27260156	RDES	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.22899511755061866	[570]	[502,443,638,682]	-4	hSpCas9	negative selection	8461502
186720127	186720150	3	-	27260156	RDES	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.5400601878805136	[529]	[568,1043,844,1154]	8	hSpCas9	negative selection	8461503
186720125	186720148	3	+	27260156	RDES	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.41367436466527807	[829]	[1002,1195,1282,1696]	6	hSpCas9	negative selection	8525757
186731549	186731572	3	-	27260156	RDES	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.14430656208121118	[1025]	[1095,1237,1505,1410]	2	hSpCas9	negative selection	8525758
186731608	186731631	3	+	27260156	RDES	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.22375775914738072	[161]	[171,136,163,158]	-4	hSpCas9	negative selection	8525759
186732518	186732541	3	+	27260156	PC3	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.3681759889132612	[292]	[217,303,552,548]	7	hSpCas9	negative selection	8582752
186732522	186732545	3	-	27260156	PC3	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.25417697031111447	[570]	[443,807,835,714]	5	hSpCas9	negative selection	8582753
186720127	186720150	3	-	27260156	PC3	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	-0.0644564784247059	[529]	[274,528,848,559]	-1	hSpCas9	negative selection	8582754
186720125	186720148	3	+	27260156	PC3	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.41731711675986793	[829]	[655,954,1286,1721]	8	hSpCas9	negative selection	8647008
186731549	186731572	3	-	27260156	PC3	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.028866349876072617	[1025]	[701,1003,1499,1194]	0	hSpCas9	negative selection	8647009
186731608	186731631	3	+	27260156	PC3	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.13002709391522926	[161]	[71,112,284,199]	-3	hSpCas9	negative selection	8647010
186732518	186732541	3	+	27260156	PATU8988T	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	-0.23481233121812262	[292]	[224,203,212,323]	-4	hSpCas9	negative selection	8704003
186732522	186732545	3	-	27260156	PATU8988T	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.3781636712864564	[570]	[762,641,855,587]	6	hSpCas9	negative selection	8704004
186720127	186720150	3	-	27260156	PATU8988T	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.5005943712141572	[529]	[602,728,751,821]	8	hSpCas9	negative selection	8704005
186720125	186720148	3	+	27260156	PATU8988T	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.4674772892608834	[829]	[1206,968,1118,1128]	7	hSpCas9	negative selection	8768259
186731549	186731572	3	-	27260156	PATU8988T	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.10986790031675664	[1025]	[1141,1404,882,866]	2	hSpCas9	negative selection	8768260
186731608	186731631	3	+	27260156	PATU8988T	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.21921469283115957	[161]	[53,91,224,163]	-4	hSpCas9	negative selection	8768261
186732518	186732541	3	+	27260156	T47D	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.245322828309393	[292]	[299,367,501,450]	5	hSpCas9	negative selection	8825254
186732522	186732545	3	-	27260156	T47D	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.5721703862498342	[570]	[482,433,409,464]	-8	hSpCas9	negative selection	8825255
186720127	186720150	3	-	27260156	T47D	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.15025092501564724	[529]	[771,613,682,677]	3	hSpCas9	negative selection	8825256
186720125	186720148	3	+	27260156	T47D	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.19630191480525205	[829]	[1078,1027,1163,1167]	4	hSpCas9	negative selection	8889510
186731549	186731572	3	-	27260156	T47D	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.1268370632144299	[1025]	[1110,942,1165,1172]	-3	hSpCas9	negative selection	8889511
186731608	186731631	3	+	27260156	T47D	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.259127787301896	[161]	[160,118,165,188]	-5	hSpCas9	negative selection	8889512
186732518	186732541	3	+	27260156	SU8686	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.8527375315689946	[292]	[415,469,665,573]	9	hSpCas9	negative selection	8946505
186732522	186732545	3	-	27260156	SU8686	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.1220485973375518	[570]	[566,575,603,743]	2	hSpCas9	negative selection	8946506
186720127	186720150	3	-	27260156	SU8686	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	-0.00195047720943195	[529]	[432,405,581,735]	0	hSpCas9	negative selection	8946507
186720125	186720148	3	+	27260156	SU8686	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.22949484136213605	[829]	[891,788,1051,1188]	4	hSpCas9	negative selection	9010761
186731549	186731572	3	-	27260156	SU8686	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.0025226646933171892	[1025]	[1022,923,1041,1105]	0	hSpCas9	negative selection	9010762
186731608	186731631	3	+	27260156	SU8686	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.5134499874584355	[161]	[54,68,213,128]	-7	hSpCas9	negative selection	9010763
186732518	186732541	3	+	27260156	SKES1	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.6169141201575183	[292]	[644,487,355,344]	9	hSpCas9	negative selection	9067756
186732522	186732545	3	-	27260156	SKES1	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.04591084245322427	[570]	[800,635,377,445]	-1	hSpCas9	negative selection	9067757
186720127	186720150	3	-	27260156	SKES1	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.38236588148617384	[529]	[705,811,653,604]	7	hSpCas9	negative selection	9067758
186720125	186720148	3	+	27260156	SKES1	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.13424112260917076	[829]	[1037,1011,748,863]	3	hSpCas9	negative selection	9132012
186731549	186731572	3	-	27260156	SKES1	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.01479821360157385	[1025]	[911,1121,1038,971]	0	hSpCas9	negative selection	9132013
186731608	186731631	3	+	27260156	SKES1	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.15770485755265629	[161]	[166,98,130,174]	-3	hSpCas9	negative selection	9132014
186732518	186732541	3	+	27260156	TOV112D	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	0.5363548155435149	[292]	[443,396,494,361]	8	hSpCas9	negative selection	9189007
186732522	186732545	3	-	27260156	TOV112D	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.08769773698073743	[570]	[433,871,448,471]	-2	hSpCas9	negative selection	9189008
186720127	186720150	3	-	27260156	TOV112D	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	-0.0317276028430262	[529]	[487,611,352,639]	0	hSpCas9	negative selection	9189009
186720125	186720148	3	+	27260156	TOV112D	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.49336717084152726	[829]	[1192,1543,906,1129]	8	hSpCas9	negative selection	9253263
186731549	186731572	3	-	27260156	TOV112D	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.11111040746959411	[1025]	[1307,1434,851,943]	2	hSpCas9	negative selection	9253264
186731608	186731631	3	+	27260156	TOV112D	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.10743223389946088	[161]	[158,104,263,152]	2	hSpCas9	negative selection	9253265
186732518	186732541	3	+	27260156	TC71	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	-0.05512186099510907	[292]	[381,282,235,308]	-1	hSpCas9	negative selection	9310258
186732522	186732545	3	-	27260156	TC71	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	0.16746169454528537	[570]	[606,756,609,785]	4	hSpCas9	negative selection	9310259
186720127	186720150	3	-	27260156	TC71	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.136652882224162	[529]	[594,529,684,690]	3	hSpCas9	negative selection	9310260
186720125	186720148	3	+	27260156	TC71	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.17304988063961846	[829]	[1113,1037,973,876]	4	hSpCas9	negative selection	9374514
186731549	186731572	3	-	27260156	TC71	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	-0.07075015843230936	[1025]	[866,995,1037,1307]	-2	hSpCas9	negative selection	9374515
186731608	186731631	3	+	27260156	TC71	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	0.44596002893223474	[161]	[166,333,206,240]	8	hSpCas9	negative selection	9374516
186732518	186732541	3	+	27260156	TC32	viability	ACCACCTACCAAGATTTGCGTGG	KNG1	ENSG00000113889	-0.001532483200746837	[292]	[236,277,257,311]	0	hSpCas9	negative selection	9431509
186732522	186732545	3	-	27260156	TC32	viability	CAGCCCACGCAAATCTTGGTAGG	KNG1	ENSG00000113889	-0.3926351376886236	[570]	[408,256,537,491]	-6	hSpCas9	negative selection	9431510
186720127	186720150	3	-	27260156	TC32	viability	CTCCTTGATTTCGTACTTGAAGG	KNG1	ENSG00000113889	0.4398981154470852	[529]	[614,557,847,724]	7	hSpCas9	negative selection	9431511
186720125	186720148	3	+	27260156	TC32	viability	TTCCTTCAAGTACGAAATCAAGG	KNG1	ENSG00000113889	0.2628423996883771	[829]	[902,731,1334,862]	5	hSpCas9	negative selection	9495765
186731549	186731572	3	-	27260156	TC32	viability	TGCATTATCTGTACATTCACCGG	KNG1	ENSG00000113889	0.22041908357749085	[1025]	[955,993,1671,957]	4	hSpCas9	negative selection	9495766
186731608	186731631	3	+	27260156	TC32	viability	CAGAACTGTGACATTTATCCAGG	KNG1	ENSG00000113889	-0.43950387022463655	[161]	[72,51,170,189]	-7	hSpCas9	negative selection	9495767
186725122	186725145	3	-	27869803	HPAFII	viability after 27 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.6193129090720569	[300]	[403,108,NaN]	5	hSpCas9	negative selection	9583931
186727332	186727355	3	-	27869803	HPAFII	viability after 27 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	-0.2916474668086852	[206]	[113,67,NaN]	-2	hSpCas9	negative selection	9583932
186732485	186732508	3	+	27869803	HPAFII	viability after 27 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.6845700577912304	[111]	[46,27,NaN]	-5	hSpCas9	negative selection	9583933
186739387	186739410	3	+	27869803	HPAFII	viability after 27 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.9101875369253746	[219]	[296,150,NaN]	7	hSpCas9	negative selection	9583934
186741747	186741770	3	+	27869803	HPAFII	viability after 27 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	1.2727206461716096	[592]	[815,700,NaN]	9	hSpCas9	negative selection	9583935
186743711	186743734	3	+	27869803	HPAFII	viability after 27 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	-0.0721004711917479	[410]	[222,190,NaN]	0	hSpCas9	negative selection	9583936
186725122	186725145	3	-	27869803	HPAFII	viability after 15 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.3828324736913994	[300]	[392,157,NaN]	-4	hSpCas9	negative selection	9666380
186727332	186727355	3	-	27869803	HPAFII	viability after 15 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	0.30856753854812474	[206]	[515,125,NaN]	3	hSpCas9	negative selection	9666381
186732485	186732508	3	+	27869803	HPAFII	viability after 15 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.17831987457577347	[111]	[188,54,NaN]	-2	hSpCas9	negative selection	9666382
186739387	186739410	3	+	27869803	HPAFII	viability after 15 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.7775199146593355	[219]	[601,282,NaN]	8	hSpCas9	negative selection	9666383
186741747	186741770	3	+	27869803	HPAFII	viability after 15 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.5774952370087421	[592]	[1164,817,NaN]	6	hSpCas9	negative selection	9666384
186743711	186743734	3	+	27869803	HPAFII	viability after 15 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	-0.2966884688890974	[410]	[440,308,NaN]	-3	hSpCas9	negative selection	9666385
186725122	186725145	3	-	27869803	ASPC1	viability after 36 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.8027024751837913	[828]	[234,167,113]	-7	hSpCas9	negative selection	9748829
186727332	186727355	3	-	27869803	ASPC1	viability after 36 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	-0.4312150242145971	[588]	[371,43,82]	-4	hSpCas9	negative selection	9748830
186732485	186732508	3	+	27869803	ASPC1	viability after 36 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	0.3651881478841841	[488]	[329,189,163]	3	hSpCas9	negative selection	9748831
186739387	186739410	3	+	27869803	ASPC1	viability after 36 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.954363705382365	[661]	[727,363,312]	8	hSpCas9	negative selection	9748832
186741747	186741770	3	+	27869803	ASPC1	viability after 36 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.6631350154040689	[1353]	[1207,987,227]	6	hSpCas9	negative selection	9748833
186743711	186743734	3	+	27869803	ASPC1	viability after 36 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	-0.14624083665543186	[1095]	[278,405,340]	-1	hSpCas9	negative selection	9748834
186725122	186725145	3	-	27869803	PATU8988S	viability after 35 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.16850750397516878	[626]	[200,366,NaN]	2	hSpCas9	negative selection	9831278
186727332	186727355	3	-	27869803	PATU8988S	viability after 35 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	-0.4910733166472988	[592]	[137,201,NaN]	-5	hSpCas9	negative selection	9831279
186732485	186732508	3	+	27869803	PATU8988S	viability after 35 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.5053066473206543	[422]	[129,109,NaN]	-5	hSpCas9	negative selection	9831280
186739387	186739410	3	+	27869803	PATU8988S	viability after 35 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.07162492717918822	[501]	[199,224,NaN]	0	hSpCas9	negative selection	9831281
186741747	186741770	3	+	27869803	PATU8988S	viability after 35 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.49019366881096116	[1195]	[718,633,NaN]	5	hSpCas9	negative selection	9831282
186743711	186743734	3	+	27869803	PATU8988S	viability after 35 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	-0.04011781202622533	[794]	[269,352,NaN]	0	hSpCas9	negative selection	9831283
186725122	186725145	3	-	27869803	PATU8988S	viability after 31 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.02052295374259716	[626]	[224,289,NaN]	0	hSpCas9	negative selection	9913727
186727332	186727355	3	-	27869803	PATU8988S	viability after 31 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	-0.35038382770652593	[592]	[133,250,NaN]	-4	hSpCas9	negative selection	9913728
186732485	186732508	3	+	27869803	PATU8988S	viability after 31 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.05815627148240876	[422]	[183,133,NaN]	0	hSpCas9	negative selection	9913729
186739387	186739410	3	+	27869803	PATU8988S	viability after 31 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	0.16268742877903944	[501]	[143,325,NaN]	2	hSpCas9	negative selection	9913730
186741747	186741770	3	+	27869803	PATU8988S	viability after 31 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	0.5779324317414842	[1195]	[655,782,NaN]	7	hSpCas9	negative selection	9913731
186743711	186743734	3	+	27869803	PATU8988S	viability after 31 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.03231367548224495	[794]	[233,438,NaN]	0	hSpCas9	negative selection	9913732
186725122	186725145	3	-	27869803	HPAFII	viability after 35 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.2833906944585338	[300]	[271,87,NaN]	1	hSpCas9	negative selection	9996176
186727332	186727355	3	-	27869803	HPAFII	viability after 35 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	0.3969607572431555	[206]	[224,39,NaN]	2	hSpCas9	negative selection	9996177
186732485	186732508	3	+	27869803	HPAFII	viability after 35 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	-0.3070447442218731	[111]	[58,30,NaN]	-2	hSpCas9	negative selection	9996178
186739387	186739410	3	+	27869803	HPAFII	viability after 35 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	1.5757854464755556	[219]	[458,188,NaN]	9	hSpCas9	negative selection	9996179
186741747	186741770	3	+	27869803	HPAFII	viability after 35 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	1.648263290898631	[592]	[956,922,NaN]	9	hSpCas9	negative selection	9996180
186743711	186743734	3	+	27869803	HPAFII	viability after 35 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	0.6544363598327121	[410]	[144,532,NaN]	4	hSpCas9	negative selection	9996181
186725122	186725145	3	-	27869803	HPAFII	viability after 31 days	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.5460730000226859	[300]	[383,96,NaN]	4	hSpCas9	negative selection	10078625
186727332	186727355	3	-	27869803	HPAFII	viability after 31 days	GCCTACTTACACCATTCCAAAGG	KNG1	ENSG00000113889	0.05525148219167056	[206]	[169,66,NaN]	0	hSpCas9	negative selection	10078626
186732485	186732508	3	+	27869803	HPAFII	viability after 31 days	AAACCTGATCCTTTCAGGGAAGG	KNG1	ENSG00000113889	0.036284613071480676	[111]	[96,28,NaN]	0	hSpCas9	negative selection	10078627
186739387	186739410	3	+	27869803	HPAFII	viability after 31 days	TACTGTCAACTGTCAACCACTGG	KNG1	ENSG00000113889	1.385837701407453	[219]	[459,172,NaN]	8	hSpCas9	negative selection	10078628
186741747	186741770	3	+	27869803	HPAFII	viability after 31 days	CAAGGGCATGGGCACCAAAGAGG	KNG1	ENSG00000113889	1.3168852144819057	[592]	[808,850,NaN]	8	hSpCas9	negative selection	10078629
186743711	186743734	3	+	27869803	HPAFII	viability after 31 days	CTAAGGTCCTGCGAGTACAAGGG	KNG1	ENSG00000113889	-0.015107187019621438	[410]	[166,294,NaN]	0	hSpCas9	negative selection	10078630
186725122	186725145	3	-	28162770	P31FUJ	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.04353185325263916	[213]	[243]	0	hSpCas9	negative selection	10181016
186732526	186732549	3	-	28162770	P31FUJ	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.4503134158075732	[463]	[744]	5	hSpCas9	negative selection	10181017
186717578	186717601	3	+	28162770	P31FUJ	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.32169501557972635	[334]	[491]	3	hSpCas9	negative selection	10181018
186722443	186722466	3	+	28162770	P31FUJ	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.17229249161688664	[181]	[240]	1	hSpCas9	negative selection	10181019
186722472	186722495	3	+	28162770	P31FUJ	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	-0.35769345224218724	[204]	[187]	-3	hSpCas9	negative selection	10181020
186732519	186732542	3	+	28162770	P31FUJ	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	0.20672985678521394	[218]	[296]	2	hSpCas9	negative selection	10181021
186739403	186739426	3	-	28162770	P31FUJ	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	0.6158461788013998	[245]	[442]	7	hSpCas9	negative selection	10181022
186717614	186717637	3	+	28162770	P31FUJ	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	0.5236407642511314	[102]	[173]	6	hSpCas9	negative selection	10181023
186720150	186720173	3	+	28162770	P31FUJ	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.9698269621006393	[314]	[724]	9	hSpCas9	negative selection	10181024
186717556	186717579	3	-	28162770	P31FUJ	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	0.5636644015004895	[189]	[329]	6	hSpCas9	negative selection	10181025
186725122	186725145	3	-	28162770	TF1	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10350382
186732526	186732549	3	-	28162770	TF1	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	NaN	[NaN]	[487]	1	hSpCas9	negative selection	10350383
186717578	186717601	3	+	28162770	TF1	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	NaN	[NaN]	[199]	1	hSpCas9	negative selection	10350384
186722443	186722466	3	+	28162770	TF1	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	NaN	[NaN]	[119]	1	hSpCas9	negative selection	10350385
186722472	186722495	3	+	28162770	TF1	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	NaN	[NaN]	[86]	1	hSpCas9	negative selection	10350386
186732519	186732542	3	+	28162770	TF1	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	NaN	[NaN]	[150]	1	hSpCas9	negative selection	10350387
186739403	186739426	3	-	28162770	TF1	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10350388
186717614	186717637	3	+	28162770	TF1	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10350389
186720150	186720173	3	+	28162770	TF1	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	NaN	[NaN]	[185]	1	hSpCas9	negative selection	10350390
186717556	186717579	3	-	28162770	TF1	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	NaN	[NaN]	[208]	1	hSpCas9	negative selection	10350391
186725122	186725145	3	-	28162770	SKM1	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.10377266643738525	[61]	[101]	-1	hSpCas9	negative selection	10519748
186732526	186732549	3	-	28162770	SKM1	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.15223520591291262	[112]	[221]	1	hSpCas9	negative selection	10519749
186717578	186717601	3	+	28162770	SKM1	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	-0.18457177740671388	[89]	[139]	-1	hSpCas9	negative selection	10519750
186722443	186722466	3	+	28162770	SKM1	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	-1.1439297929093677	[54]	[43]	-7	hSpCas9	negative selection	10519751
186722472	186722495	3	+	28162770	SKM1	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	-0.024818581021692473	[60]	[105]	0	hSpCas9	negative selection	10519752
186732519	186732542	3	+	28162770	SKM1	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	-0.2995806633695621	[54]	[78]	-3	hSpCas9	negative selection	10519753
186739403	186739426	3	-	28162770	SKM1	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	-0.32818708535904456	[48]	[68]	-3	hSpCas9	negative selection	10519754
186717614	186717637	3	+	28162770	SKM1	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	1.2035333940851323	[13]	[56]	9	hSpCas9	negative selection	10519755
186720150	186720173	3	+	28162770	SKM1	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.3557854211932775	[60]	[137]	3	hSpCas9	negative selection	10519756
186717556	186717579	3	-	28162770	SKM1	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	-0.8744691179161412	[55]	[53]	-6	hSpCas9	negative selection	10519757
186725122	186725145	3	-	28162770	SKM1	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.10377266643738525	[61]	[101]	-1	hSpCas9	negative selection	10689114
186732526	186732549	3	-	28162770	SKM1	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.15223520591291262	[112]	[221]	1	hSpCas9	negative selection	10689115
186717578	186717601	3	+	28162770	SKM1	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	-0.18457177740671388	[89]	[139]	-1	hSpCas9	negative selection	10689116
186722443	186722466	3	+	28162770	SKM1	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	-1.1439297929093677	[54]	[43]	-7	hSpCas9	negative selection	10689117
186722472	186722495	3	+	28162770	SKM1	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	-0.024818581021692473	[60]	[105]	0	hSpCas9	negative selection	10689118
186732519	186732542	3	+	28162770	SKM1	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	-0.2995806633695621	[54]	[78]	-3	hSpCas9	negative selection	10689119
186739403	186739426	3	-	28162770	SKM1	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	-0.32818708535904456	[48]	[68]	-3	hSpCas9	negative selection	10689120
186717614	186717637	3	+	28162770	SKM1	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	1.2035333940851323	[13]	[56]	9	hSpCas9	negative selection	10689121
186720150	186720173	3	+	28162770	SKM1	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.3557854211932775	[60]	[137]	3	hSpCas9	negative selection	10689122
186717556	186717579	3	-	28162770	SKM1	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	-0.8744691179161412	[55]	[53]	-6	hSpCas9	negative selection	10689123
186725122	186725145	3	-	28162770	PL21	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	1.2718753680882346	[254]	[267]	9	hSpCas9	negative selection	10858480
186732526	186732549	3	-	28162770	PL21	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.6990783713771092	[333]	[235]	6	hSpCas9	negative selection	10858481
186717578	186717601	3	+	28162770	PL21	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	-0.7079378960696406	[303]	[80]	-5	hSpCas9	negative selection	10858482
186722443	186722466	3	+	28162770	PL21	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	1.0852375196765176	[208]	[192]	8	hSpCas9	negative selection	10858483
186722472	186722495	3	+	28162770	PL21	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	1.0232618524052408	[285]	[252]	8	hSpCas9	negative selection	10858484
186732519	186732542	3	+	28162770	PL21	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	0.33020015505369316	[211]	[115]	3	hSpCas9	negative selection	10858485
186739403	186739426	3	-	28162770	PL21	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	0.005123632084177349	[173]	[75]	0	hSpCas9	negative selection	10858486
186717614	186717637	3	+	28162770	PL21	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	2.2537775780913933	[65]	[136]	9	hSpCas9	negative selection	10858487
186720150	186720173	3	+	28162770	PL21	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.5156414402172497	[224]	[139]	4	hSpCas9	negative selection	10858488
186717556	186717579	3	-	28162770	PL21	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	-0.4075429627319196	[127]	[41]	-3	hSpCas9	negative selection	10858489
186725122	186725145	3	-	28162770	P31FUJ	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.04353185325263916	[213]	[243]	0	hSpCas9	negative selection	11027846
186732526	186732549	3	-	28162770	P31FUJ	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.4503134158075732	[463]	[744]	5	hSpCas9	negative selection	11027847
186717578	186717601	3	+	28162770	P31FUJ	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.32169501557972635	[334]	[491]	3	hSpCas9	negative selection	11027848
186722443	186722466	3	+	28162770	P31FUJ	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.17229249161688664	[181]	[240]	1	hSpCas9	negative selection	11027849
186722472	186722495	3	+	28162770	P31FUJ	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	-0.35769345224218724	[204]	[187]	-3	hSpCas9	negative selection	11027850
186732519	186732542	3	+	28162770	P31FUJ	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	0.20672985678521394	[218]	[296]	2	hSpCas9	negative selection	11027851
186739403	186739426	3	-	28162770	P31FUJ	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	0.6158461788013998	[245]	[442]	7	hSpCas9	negative selection	11027852
186717614	186717637	3	+	28162770	P31FUJ	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	0.5236407642511314	[102]	[173]	6	hSpCas9	negative selection	11027853
186720150	186720173	3	+	28162770	P31FUJ	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.9698269621006393	[314]	[724]	9	hSpCas9	negative selection	11027854
186717556	186717579	3	-	28162770	P31FUJ	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	0.5636644015004895	[189]	[329]	6	hSpCas9	negative selection	11027855
186725122	186725145	3	-	28162770	OCIAML5	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	1.5844506558252984	[74]	[405]	9	hSpCas9	negative selection	11197212
186732526	186732549	3	-	28162770	OCIAML5	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	-0.024177237757621928	[288]	[512]	0	hSpCas9	negative selection	11197213
186717578	186717601	3	+	28162770	OCIAML5	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.2502951467656808	[135]	[291]	2	hSpCas9	negative selection	11197214
186722443	186722466	3	+	28162770	OCIAML5	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.8136569418209957	[109]	[348]	7	hSpCas9	negative selection	11197215
186722472	186722495	3	+	28162770	OCIAML5	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	-0.26102955573315645	[157]	[237]	-2	hSpCas9	negative selection	11197216
186732519	186732542	3	+	28162770	OCIAML5	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	0.38570107635936696	[119]	[282]	3	hSpCas9	negative selection	11197217
186739403	186739426	3	-	28162770	OCIAML5	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	-0.6005278038680326	[188]	[224]	-4	hSpCas9	negative selection	11197218
186717614	186717637	3	+	28162770	OCIAML5	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	0.8390953336890843	[47]	[154]	7	hSpCas9	negative selection	11197219
186720150	186720173	3	+	28162770	OCIAML5	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.01829814871940738	[191]	[350]	0	hSpCas9	negative selection	11197220
186717556	186717579	3	-	28162770	OCIAML5	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	0.5328509400385116	[120]	[315]	4	hSpCas9	negative selection	11197221
186725122	186725145	3	-	28162770	EOL1	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.6622993614199737	[366]	[305]	6	hSpCas9	negative selection	11366578
186732526	186732549	3	-	28162770	EOL1	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	-0.3930673304457454	[500]	[200]	-3	hSpCas9	negative selection	11366579
186717578	186717601	3	+	28162770	EOL1	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.5320780291969658	[591]	[450]	5	hSpCas9	negative selection	11366580
186722443	186722466	3	+	28162770	EOL1	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	1.418195105545745	[374]	[527]	9	hSpCas9	negative selection	11366581
186722472	186722495	3	+	28162770	EOL1	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.5449231007824478	[388]	[298]	5	hSpCas9	negative selection	11366582
186732519	186732542	3	+	28162770	EOL1	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	0.6206410843212127	[357]	[289]	5	hSpCas9	negative selection	11366583
186739403	186739426	3	-	28162770	EOL1	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	-0.044291296943004876	[228]	[116]	0	hSpCas9	negative selection	11366584
186717614	186717637	3	+	28162770	EOL1	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	1.2095247302850054	[86]	[105]	8	hSpCas9	negative selection	11366585
186720150	186720173	3	+	28162770	EOL1	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.16870071164579326	[281]	[166]	1	hSpCas9	negative selection	11366586
186717556	186717579	3	-	28162770	EOL1	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	0.6508996917118888	[190]	[157]	6	hSpCas9	negative selection	11366587
186725122	186725145	3	-	28162770	MOLM13	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	1.0438180704006736	[266]	[397]	7	hSpCas9	negative selection	11535944
186732526	186732549	3	-	28162770	MOLM13	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.18201036254172265	[661]	[542]	1	hSpCas9	negative selection	11535945
186717578	186717601	3	+	28162770	MOLM13	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.7453428472913363	[447]	[542]	5	hSpCas9	negative selection	11535946
186722443	186722466	3	+	28162770	MOLM13	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	0.735211145781471	[279]	[336]	5	hSpCas9	negative selection	11535947
186722472	186722495	3	+	28162770	MOLM13	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.8639616024796762	[401]	[528]	6	hSpCas9	negative selection	11535948
186732519	186732542	3	+	28162770	MOLM13	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	0.985737686407198	[307]	[440]	7	hSpCas9	negative selection	11535949
186739403	186739426	3	-	28162770	MOLM13	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	0.3662179636496734	[337]	[314]	2	hSpCas9	negative selection	11535950
186717614	186717637	3	+	28162770	MOLM13	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	0.6258417413208152	[120]	[134]	5	hSpCas9	negative selection	11535951
186720150	186720173	3	+	28162770	MOLM13	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	1.027673319269738	[288]	[425]	7	hSpCas9	negative selection	11535952
186717556	186717579	3	-	28162770	MOLM13	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	-0.765782964657872	[213]	[90]	-4	hSpCas9	negative selection	11535953
186725122	186725145	3	-	28162770	HEL	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.8262684309993508	[257]	[292]	7	hSpCas9	negative selection	11705310
186732526	186732549	3	-	28162770	HEL	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.8091321424724162	[408]	[458]	7	hSpCas9	negative selection	11705311
186717578	186717601	3	+	28162770	HEL	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.164573354156049	[435]	[312]	1	hSpCas9	negative selection	11705312
186722443	186722466	3	+	28162770	HEL	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	-0.25034596408313126	[337]	[181]	-2	hSpCas9	negative selection	11705313
186722472	186722495	3	+	28162770	HEL	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.4709724837338771	[293]	[260]	4	hSpCas9	negative selection	11705314
186732519	186732542	3	+	28162770	HEL	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	0.47826826065015265	[296]	[264]	4	hSpCas9	negative selection	11705315
186739403	186739426	3	-	28162770	HEL	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	-0.022842128929083966	[229]	[144]	0	hSpCas9	negative selection	11705316
186717614	186717637	3	+	28162770	HEL	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	0.17435190812857937	[100]	[72]	1	hSpCas9	negative selection	11705317
186720150	186720173	3	+	28162770	HEL	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.8612953163763513	[268]	[312]	7	hSpCas9	negative selection	11705318
186717556	186717579	3	-	28162770	HEL	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	0.6532312058179994	[136]	[137]	5	hSpCas9	negative selection	11705319
186725122	186725145	3	-	28162770	MV411	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	1.4226374942657622	[181]	[410]	9	hSpCas9	negative selection	11874676
186732526	186732549	3	-	28162770	MV411	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.12375272786428937	[425]	[390]	1	hSpCas9	negative selection	11874677
186717578	186717601	3	+	28162770	MV411	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.5453424164636216	[326]	[401]	5	hSpCas9	negative selection	11874678
186722443	186722466	3	+	28162770	MV411	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	-0.5028864262384498	[216]	[128]	-4	hSpCas9	negative selection	11874679
186722472	186722495	3	+	28162770	MV411	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.06559922779696242	[227]	[200]	0	hSpCas9	negative selection	11874680
186732519	186732542	3	+	28162770	MV411	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	0.221324710463644	[222]	[218]	2	hSpCas9	negative selection	11874681
186739403	186739426	3	-	28162770	MV411	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	0.16995879810505787	[152]	[144]	1	hSpCas9	negative selection	11874682
186717614	186717637	3	+	28162770	MV411	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	1.1161930175045227	[45]	[83]	8	hSpCas9	negative selection	11874683
186720150	186720173	3	+	28162770	MV411	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.0494981731708663	[233]	[203]	0	hSpCas9	negative selection	11874684
186717556	186717579	3	-	28162770	MV411	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	-0.37788268755452165	[144]	[93]	-3	hSpCas9	negative selection	11874685
186725122	186725145	3	-	28162770	MONOMAC1	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	0.5041186711661251	[154]	[251]	5	hSpCas9	negative selection	12044042
186732526	186732549	3	-	28162770	MONOMAC1	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.04787702820615558	[226]	[268]	0	hSpCas9	negative selection	12044043
186717578	186717601	3	+	28162770	MONOMAC1	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.1678771727934537	[204]	[263]	1	hSpCas9	negative selection	12044044
186722443	186722466	3	+	28162770	MONOMAC1	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	-0.7518973159912907	[165]	[112]	-6	hSpCas9	negative selection	12044045
186722472	186722495	3	+	28162770	MONOMAC1	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	-0.8421941296994562	[207]	[132]	-6	hSpCas9	negative selection	12044046
186732519	186732542	3	+	28162770	MONOMAC1	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	-0.523687352189319	[152]	[121]	-4	hSpCas9	negative selection	12044047
186739403	186739426	3	-	28162770	MONOMAC1	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	0.4504467382196611	[142]	[223]	4	hSpCas9	negative selection	12044048
186717614	186717637	3	+	28162770	MONOMAC1	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	1.109624491174498	[18]	[46]	8	hSpCas9	negative selection	12044049
186720150	186720173	3	+	28162770	MONOMAC1	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.47795785452407524	[175]	[280]	5	hSpCas9	negative selection	12044050
186717556	186717579	3	-	28162770	MONOMAC1	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	-1.3225677291434128	[95]	[43]	-7	hSpCas9	negative selection	12044051
186725122	186725145	3	-	28162770	OCIAML2	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.06853138167081552	[48]	[258]	0	hSpCas9	negative selection	12213408
186732526	186732549	3	-	28162770	OCIAML2	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.6320558387324029	[60]	[523]	6	hSpCas9	negative selection	12213409
186717578	186717601	3	+	28162770	OCIAML2	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.7297972645974952	[51]	[477]	7	hSpCas9	negative selection	12213410
186722443	186722466	3	+	28162770	OCIAML2	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	-1.0365339901476327	[46]	[126]	-6	hSpCas9	negative selection	12213411
186722472	186722495	3	+	28162770	OCIAML2	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	-0.4926561315721602	[65]	[259]	-4	hSpCas9	negative selection	12213412
186732519	186732542	3	+	28162770	OCIAML2	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	0.8595187764501696	[34]	[351]	8	hSpCas9	negative selection	12213413
186739403	186739426	3	-	28162770	OCIAML2	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	-1.4706298252421612	[39]	[79]	-7	hSpCas9	negative selection	12213414
186717614	186717637	3	+	28162770	OCIAML2	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	0.5703974430178935	[12]	[106]	5	hSpCas9	negative selection	12213415
186720150	186720173	3	+	28162770	OCIAML2	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.20866005802714815	[36]	[236]	2	hSpCas9	negative selection	12213416
186717556	186717579	3	-	28162770	OCIAML2	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	0.2017955167293345	[15]	[101]	2	hSpCas9	negative selection	12213417
186725122	186725145	3	-	28162770	OCIAML3	viability	ATATAGGATGCACACAGCCGAGG	KNG1	ENSG00000113889	-0.2584046085397242	[62]	[158]	-2	hSpCas9	negative selection	12382774
186732526	186732549	3	-	28162770	OCIAML3	viability	GGGGCAGCCCACGCAAATCTTGG	KNG1	ENSG00000113889	0.12978256509430985	[98]	[326]	1	hSpCas9	negative selection	12382775
186717578	186717601	3	+	28162770	OCIAML3	viability	GCTGCTACTAAGTTTAACCCAGG	KNG1	ENSG00000113889	0.06650589340416979	[92]	[293]	0	hSpCas9	negative selection	12382776
186722443	186722466	3	+	28162770	OCIAML3	viability	GGAGAATGCACGGCAACCGTGGG	KNG1	ENSG00000113889	-0.5529803720641084	[51]	[106]	-4	hSpCas9	negative selection	12382777
186722472	186722495	3	+	28162770	OCIAML3	viability	GAGCAGTACGAAATTCTCCGTGG	KNG1	ENSG00000113889	0.06100235792524972	[66]	[210]	0	hSpCas9	negative selection	12382778
186732519	186732542	3	+	28162770	OCIAML3	viability	CCACCTACCAAGATTTGCGTGGG	KNG1	ENSG00000113889	-1.5712875638240793	[62]	[63]	-8	hSpCas9	negative selection	12382779
186739403	186739426	3	-	28162770	OCIAML3	viability	TAGAATCATACCATTCCCAGTGG	KNG1	ENSG00000113889	0.11748726632592466	[39]	[130]	1	hSpCas9	negative selection	12382780
186717614	186717637	3	+	28162770	OCIAML3	viability	GGAAATTGACTGCAATGACAAGG	KNG1	ENSG00000113889	-0.7094848577440993	[25]	[47]	-5	hSpCas9	negative selection	12382781
186720150	186720173	3	+	28162770	OCIAML3	viability	GGGGATTGTCCTGTTCAAAGTGG	KNG1	ENSG00000113889	0.44251823570095095	[77]	[319]	4	hSpCas9	negative selection	12382782
186717556	186717579	3	-	28162770	OCIAML3	viability	CCTGGAGCAGAGGAAAAGGATGG	KNG1	ENSG00000113889	0.8134961862692733	[35]	[190]	7	hSpCas9	negative selection	12382783