Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 3952
• Symbol: LEP
• Description: leptin

DataSource: http://genomecrispr.dkfz.de/#!/results/LEP

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
128252033	128252056	7	-	26472758	Jiyoye	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.0446053021211652	[53]	[41]	0	hSpCas9	negative selection	89945
128254734	128254757	7	+	26472758	Jiyoye	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-1.7448277119391764	[39]	[8]	-8	hSpCas9	negative selection	89946
128252116	128252139	7	-	26472758	Jiyoye	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.27691899555453164	[138]	[126]	2	hSpCas9	negative selection	89947
128252137	128252160	7	-	26472758	Jiyoye	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.7443555602534895	[413]	[522]	5	hSpCas9	negative selection	89948
128252005	128252028	7	+	26472758	Jiyoye	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	1.115148772332373	[190]	[311]	7	hSpCas9	negative selection	89949
128252019	128252042	7	+	26472758	Jiyoye	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.3540640450463113	[580]	[559]	2	hSpCas9	negative selection	89950
128254568	128254591	7	-	26472758	Jiyoye	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.2590872213171309	[72]	[45]	-2	hSpCas9	negative selection	89951
128254714	128254737	7	+	26472758	Jiyoye	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	-0.4217790771578992	[285]	[160]	-3	hSpCas9	negative selection	89952
128254457	128254480	7	-	26472758	Jiyoye	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	0.3759244475214337	[139]	[136]	3	hSpCas9	negative selection	89953
128254667	128254690	7	+	26472758	Jiyoye	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	1.2109099878847804	[113]	[198]	7	hSpCas9	negative selection	89954
128252033	128252056	7	-	26472758	KBM7	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.7251987750131026	[152,142]	[101,126]	7	hSpCas9	negative selection	281063
128254734	128254757	7	+	26472758	KBM7	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-0.3538358709947912	[264,214]	[53,117]	-3	hSpCas9	negative selection	281064
128252116	128252139	7	-	26472758	KBM7	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.5015683066706379	[699,544]	[474,353]	5	hSpCas9	negative selection	281065
128252137	128252160	7	-	26472758	KBM7	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.5588903698411474	[2068,1773]	[1478,1190]	6	hSpCas9	negative selection	281066
128252005	128252028	7	+	26472758	KBM7	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	1.2182563615100597	[1143,1116]	[1623,898]	9	hSpCas9	negative selection	281067
128252019	128252042	7	+	26472758	KBM7	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.41517692385532823	[1757,1437]	[1099,903]	4	hSpCas9	negative selection	281068
128254568	128254591	7	-	26472758	KBM7	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.14352933871897777	[342,226]	[149,91]	-1	hSpCas9	negative selection	281069
128254714	128254737	7	+	26472758	KBM7	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	0.4597309932328172	[885,759]	[386,658]	5	hSpCas9	negative selection	281070
128254457	128254480	7	-	26472758	KBM7	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	0.6408179668978846	[782,540]	[551,412]	7	hSpCas9	negative selection	281071
128254667	128254690	7	+	26472758	KBM7	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	0.5030801146660393	[723,606]	[372,502]	5	hSpCas9	negative selection	281072
128252033	128252056	7	-	26472758	Raji	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.6566872889552047	[196]	[28]	-5	hSpCas9	negative selection	472181
128254734	128254757	7	+	26472758	Raji	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-0.2879177458439822	[120]	[22]	-2	hSpCas9	negative selection	472182
128252116	128252139	7	-	26472758	Raji	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.5421034005141431	[363]	[122]	5	hSpCas9	negative selection	472183
128252137	128252160	7	-	26472758	Raji	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.5867898537721628	[788]	[274]	5	hSpCas9	negative selection	472184
128252005	128252028	7	+	26472758	Raji	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	0.5392948532168396	[509]	[171]	5	hSpCas9	negative selection	472185
128252019	128252042	7	+	26472758	Raji	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.9740059297099968	[837]	[381]	8	hSpCas9	negative selection	472186
128254568	128254591	7	-	26472758	Raji	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.35893446884893754	[209]	[37]	-3	hSpCas9	negative selection	472187
128254714	128254737	7	+	26472758	Raji	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	-0.028678014202428992	[399]	[90]	0	hSpCas9	negative selection	472188
128254457	128254480	7	-	26472758	Raji	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	-0.052487801404790146	[428]	[95]	0	hSpCas9	negative selection	472189
128254667	128254690	7	+	26472758	Raji	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	0.8610278706864359	[343]	[144]	7	hSpCas9	negative selection	472190
128252033	128252056	7	-	26472758	K562	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.11001200690824486	[100]	[78]	-1	hSpCas9	negative selection	663299
128254734	128254757	7	+	26472758	K562	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-1.8283376147688672	[121]	[28]	-7	hSpCas9	negative selection	663300
128252116	128252139	7	-	26472758	K562	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.5958910981678245	[550]	[702]	5	hSpCas9	negative selection	663301
128252137	128252160	7	-	26472758	K562	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.28740553177499395	[1553]	[1600]	2	hSpCas9	negative selection	663302
128252005	128252028	7	+	26472758	K562	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	1.1725258091846615	[863]	[1643]	8	hSpCas9	negative selection	663303
128252019	128252042	7	+	26472758	K562	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.7190055374783948	[1583]	[2200]	6	hSpCas9	negative selection	663304
128254568	128254591	7	-	26472758	K562	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.06771886402810612	[256]	[206]	0	hSpCas9	negative selection	663305
128254714	128254737	7	+	26472758	K562	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	-0.2819491191438609	[771]	[535]	-2	hSpCas9	negative selection	663306
128254457	128254480	7	-	26472758	K562	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	-0.513920517292326	[679]	[401]	-3	hSpCas9	negative selection	663307
128254667	128254690	7	+	26472758	K562	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	0.04339398410807771	[591]	[514]	0	hSpCas9	negative selection	663308
128252033	128252056	7	-	26627737	DLD1	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-1.0155747292240602	[421]	[94,95,13]	-7	hSpCas9	negative selection	834807
128254432	128254455	7	-	26627737	DLD1	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.7837613667552866	[912]	[314,563,583]	7	hSpCas9	negative selection	834808
128254541	128254564	7	+	26627737	DLD1	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	1.0974524602107638	[126]	[58,105,89]	8	hSpCas9	negative selection	834809
128254568	128254591	7	-	26627737	DLD1	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.48473966767204646	[190]	[86,18,133]	5	hSpCas9	negative selection	834810
128254670	128254693	7	+	26627737	DLD1	viability	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	0.07960305032675785	[816]	[333,233,243]	0	hSpCas9	negative selection	834811
128252033	128252056	7	-	26627737	GBM cells	viability after 5 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.33103589762884456	[318]	[129,141]	-5	hSpCas9	negative selection	917122
128254432	128254455	7	-	26627737	GBM cells	viability after 5 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.05216013518136786	[927]	[551,479]	0	hSpCas9	negative selection	917123
128254541	128254564	7	+	26627737	GBM cells	viability after 5 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.005172562276242965	[156]	[82,85]	0	hSpCas9	negative selection	917124
128254568	128254591	7	-	26627737	GBM cells	viability after 5 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.2810647912205495	[161]	[84,57]	-4	hSpCas9	negative selection	917125
128254670	128254693	7	+	26627737	GBM cells	viability after 5 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.43953667591433876	[482]	[189,191]	-6	hSpCas9	negative selection	917126
128252033	128252056	7	-	26627737	GBM cells	viability after 13 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.5515880590320845	[318]	[159,83]	-6	hSpCas9	negative selection	999437
128254432	128254455	7	-	26627737	GBM cells	viability after 13 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.04724454777900955	[927]	[511,526]	0	hSpCas9	negative selection	999438
128254541	128254564	7	+	26627737	GBM cells	viability after 13 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.09235976747890651	[156]	[140,49]	1	hSpCas9	negative selection	999439
128254568	128254591	7	-	26627737	GBM cells	viability after 13 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.3552307719239963	[161]	[119,26]	-4	hSpCas9	negative selection	999440
128254670	128254693	7	+	26627737	GBM cells	viability after 13 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.1670427861207897	[482]	[303,175]	-2	hSpCas9	negative selection	999441
128252033	128252056	7	-	26627737	GBM cells	viability after 21 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-1.2962643557501403	[318]	[68,71]	-8	hSpCas9	negative selection	1081752
128254432	128254455	7	-	26627737	GBM cells	viability after 21 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.08070900314598495	[927]	[482,470]	0	hSpCas9	negative selection	1081753
128254541	128254564	7	+	26627737	GBM cells	viability after 21 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.06817404419988382	[156]	[102,76]	0	hSpCas9	negative selection	1081754
128254568	128254591	7	-	26627737	GBM cells	viability after 21 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-1.9388452607335815	[161]	[23,21]	-8	hSpCas9	negative selection	1081755
128254670	128254693	7	+	26627737	GBM cells	viability after 21 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.5203842840670796	[482]	[195,170]	-5	hSpCas9	negative selection	1081756
128252033	128252056	7	-	26627737	RPE1	viability after 9 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.7185206851699694	[1256]	[253,219]	-5	hSpCas9	negative selection	1164067
128254432	128254455	7	-	26627737	RPE1	viability after 9 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.47051016167063553	[4109]	[901,962]	-3	hSpCas9	negative selection	1164068
128254541	128254564	7	+	26627737	RPE1	viability after 9 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-2.6522746439886213	[600]	[25,34]	-9	hSpCas9	negative selection	1164069
128254568	128254591	7	-	26627737	RPE1	viability after 9 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.39547925350597546	[196]	[21,78]	-3	hSpCas9	negative selection	1164070
128254670	128254693	7	+	26627737	RPE1	viability after 9 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.7690461263557442	[2116]	[408,362]	-5	hSpCas9	negative selection	1164071
128252033	128252056	7	-	26627737	RPE1	viability after 12 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.5292928031639654	[1256]	[250,215]	-4	hSpCas9	negative selection	1246382
128254432	128254455	7	-	26627737	RPE1	viability after 12 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.32221490500510086	[4109]	[957,803]	-2	hSpCas9	negative selection	1246383
128254541	128254564	7	+	26627737	RPE1	viability after 12 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-2.332535825374221	[600]	[33,29]	-9	hSpCas9	negative selection	1246384
128254568	128254591	7	-	26627737	RPE1	viability after 12 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	1.0964255611764147	[196]	[84,142]	6	hSpCas9	negative selection	1246385
128254670	128254693	7	+	26627737	RPE1	viability after 12 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.6529873749637142	[2116]	[402,317]	-4	hSpCas9	negative selection	1246386
128252033	128252056	7	-	26627737	RPE1	viability after 15 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.6575431362747046	[1256]	[257,193]	-4	hSpCas9	negative selection	1328697
128254432	128254455	7	-	26627737	RPE1	viability after 15 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.7373583965928645	[4109]	[759,636]	-5	hSpCas9	negative selection	1328698
128254541	128254564	7	+	26627737	RPE1	viability after 15 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-2.749904148624975	[600]	[37,12]	-9	hSpCas9	negative selection	1328699
128254568	128254591	7	-	26627737	RPE1	viability after 15 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	1.3323567046912421	[196]	[149,130]	7	hSpCas9	negative selection	1328700
128254670	128254693	7	+	26627737	RPE1	viability after 15 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.8122947508157136	[2116]	[282,396]	-5	hSpCas9	negative selection	1328701
128252033	128252056	7	-	26627737	RPE1	viability after 18 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-1.0528911215866943	[1256]	[221,100]	-6	hSpCas9	negative selection	1411012
128254432	128254455	7	-	26627737	RPE1	viability after 18 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.5809469254901862	[4109]	[930,538]	-4	hSpCas9	negative selection	1411013
128254541	128254564	7	+	26627737	RPE1	viability after 18 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-2.0437564881959784	[600]	[19,59]	-8	hSpCas9	negative selection	1411014
128254568	128254591	7	-	26627737	RPE1	viability after 18 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.20971371610096656	[196]	[15,77]	-1	hSpCas9	negative selection	1411015
128254670	128254693	7	+	26627737	RPE1	viability after 18 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.5838262580193082	[2116]	[327,437]	-4	hSpCas9	negative selection	1411016
128252033	128252056	7	-	26627737	HeLa	viability after 8 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.16851264730471283	[376]	[231,125,101]	-2	hSpCas9	negative selection	1493327
128254432	128254455	7	-	26627737	HeLa	viability after 8 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.22477849564122931	[1484]	[909,445,392]	-2	hSpCas9	negative selection	1493328
128254541	128254564	7	+	26627737	HeLa	viability after 8 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.3778047960009727	[199]	[173,55,121]	3	hSpCas9	negative selection	1493329
128254568	128254591	7	-	26627737	HeLa	viability after 8 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.6821959596672493	[153]	[150,115,67]	6	hSpCas9	negative selection	1493330
128254670	128254693	7	+	26627737	HeLa	viability after 8 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.3661127217042315	[1156]	[438,404,341]	-4	hSpCas9	negative selection	1493331
128252033	128252056	7	-	26627737	HeLa	viability after 12 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.010736971605948664	[376]	[32,148,278]	0	hSpCas9	negative selection	1575642
128254432	128254455	7	-	26627737	HeLa	viability after 12 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.8306386092963918	[1484]	[354,396,277]	-6	hSpCas9	negative selection	1575643
128254541	128254564	7	+	26627737	HeLa	viability after 12 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.7389172931118584	[199]	[150,120,143]	6	hSpCas9	negative selection	1575644
128254568	128254591	7	-	26627737	HeLa	viability after 12 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.31079479954494293	[153]	[88,13,140]	2	hSpCas9	negative selection	1575645
128254670	128254693	7	+	26627737	HeLa	viability after 12 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.7392960554994308	[1156]	[529,185,160]	-6	hSpCas9	negative selection	1575646
128252033	128252056	7	-	26627737	HeLa	viability after 15 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.4268721486952239	[376]	[242,150,225]	3	hSpCas9	negative selection	1657957
128254432	128254455	7	-	26627737	HeLa	viability after 15 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.5774800687455215	[1484]	[605,331,263]	-5	hSpCas9	negative selection	1657958
128254541	128254564	7	+	26627737	HeLa	viability after 15 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.7316185158444743	[199]	[68,38,37]	-6	hSpCas9	negative selection	1657959
128254568	128254591	7	-	26627737	HeLa	viability after 15 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.9859075905614152	[153]	[130,73,170]	7	hSpCas9	negative selection	1657960
128254670	128254693	7	+	26627737	HeLa	viability after 15 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-1.098090490742364	[1156]	[180,314,159]	-7	hSpCas9	negative selection	1657961
128252033	128252056	7	-	26627737	HeLa	viability after 18 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.3894707128454687	[376]	[151,125,225]	3	hSpCas9	negative selection	1740272
128254432	128254455	7	-	26627737	HeLa	viability after 18 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.5857973192116435	[1484]	[409,264,263]	-5	hSpCas9	negative selection	1740273
128254541	128254564	7	+	26627737	HeLa	viability after 18 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.6771643589938037	[199]	[50,30,37]	-5	hSpCas9	negative selection	1740274
128254568	128254591	7	-	26627737	HeLa	viability after 18 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.9659639158722089	[153]	[87,56,170]	7	hSpCas9	negative selection	1740275
128254670	128254693	7	+	26627737	HeLa	viability after 18 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-1.1167762773579235	[1156]	[114,261,159]	-7	hSpCas9	negative selection	1740276
128252033	128252056	7	-	26627737	HCT116	viability after 6 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	2.2791192401918785	[216]	[269,107]	9	hSpCas9	negative selection	1822587
128254432	128254455	7	-	26627737	HCT116	viability after 6 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.527606855219793	[1582]	[321,378]	3	hSpCas9	negative selection	1822588
128254541	128254564	7	+	26627737	HCT116	viability after 6 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.005137404658600797	[127]	[54,0]	0	hSpCas9	negative selection	1822589
128254568	128254591	7	-	26627737	HCT116	viability after 6 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-2.2031905483038394	[122]	[9,0]	-8	hSpCas9	negative selection	1822590
128254670	128254693	7	+	26627737	HCT116	viability after 6 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	0.11663934459750225	[969]	[310,84]	0	hSpCas9	negative selection	1822591
128252033	128252056	7	-	26627737	HCT116	viability after 8 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-1.1714268505251086	[407]	[87,91,118]	-8	hSpCas9	negative selection	1904902
128254432	128254455	7	-	26627737	HCT116	viability after 8 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.11201072227077624	[933]	[486,591,587]	1	hSpCas9	negative selection	1904903
128254541	128254564	7	+	26627737	HCT116	viability after 8 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.8121315859872238	[207]	[77,47,69]	-7	hSpCas9	negative selection	1904904
128254568	128254591	7	-	26627737	HCT116	viability after 8 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.6177656334378633	[201]	[48,79,87]	-6	hSpCas9	negative selection	1904905
128254670	128254693	7	+	26627737	HCT116	viability after 8 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.07659905544335421	[608]	[268,383,300]	-1	hSpCas9	negative selection	1904906
128252033	128252056	7	-	26627737	HCT116	viability after 9 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.21572209544091248	[216]	[54,76]	1	hSpCas9	negative selection	1987217
128254432	128254455	7	-	26627737	HCT116	viability after 9 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.32492385947485225	[1582]	[294,370]	-2	hSpCas9	negative selection	1987218
128254541	128254564	7	+	26627737	HCT116	viability after 9 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	1.5760128074848803	[127]	[78,119]	8	hSpCas9	negative selection	1987219
128254568	128254591	7	-	26627737	HCT116	viability after 9 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-1.1817863466607839	[122]	[28,2]	-7	hSpCas9	negative selection	1987220
128254670	128254693	7	+	26627737	HCT116	viability after 9 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	0.4737016595328951	[969]	[419,311]	3	hSpCas9	negative selection	1987221
128252033	128252056	7	-	26627737	HCT116	viability after 12 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-1.2244955268899993	[407]	[127,87,55]	-8	hSpCas9	negative selection	2069532
128254432	128254455	7	-	26627737	HCT116	viability after 12 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.45646793305565714	[933]	[388,341,338]	-5	hSpCas9	negative selection	2069533
128254541	128254564	7	+	26627737	HCT116	viability after 12 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-1.2341784825658215	[207]	[54,60,22]	-8	hSpCas9	negative selection	2069534
128254568	128254591	7	-	26627737	HCT116	viability after 12 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.6207923967069134	[201]	[47,70,89]	-6	hSpCas9	negative selection	2069535
128254670	128254693	7	+	26627737	HCT116	viability after 12 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.18586912343063877	[608]	[270,281,291]	-2	hSpCas9	negative selection	2069536
128252033	128252056	7	-	26627737	HCT116	viability after 15 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.9317666050592296	[407]	[158,99,113]	-7	hSpCas9	negative selection	2151847
128254432	128254455	7	-	26627737	HCT116	viability after 15 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.08331188042425519	[933]	[673,334,529]	-1	hSpCas9	negative selection	2151848
128254541	128254564	7	+	26627737	HCT116	viability after 15 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.11212770434996755	[207]	[178,58,101]	-1	hSpCas9	negative selection	2151849
128254568	128254591	7	-	26627737	HCT116	viability after 15 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.34550084362078914	[201]	[70,56,302]	3	hSpCas9	negative selection	2151850
128254670	128254693	7	+	26627737	HCT116	viability after 15 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.010971263830310773	[608]	[380,282,380]	0	hSpCas9	negative selection	2151851
128252033	128252056	7	-	26627737	HCT116	viability after 18 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-1.2075205076493905	[407]	[44,103,106]	-8	hSpCas9	negative selection	2234162
128254432	128254455	7	-	26627737	HCT116	viability after 18 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.6089881386648415	[933]	[373,256,257]	-5	hSpCas9	negative selection	2234163
128254541	128254564	7	+	26627737	HCT116	viability after 18 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.9347654272677084	[207]	[76,40,39]	-7	hSpCas9	negative selection	2234164
128254568	128254591	7	-	26627737	HCT116	viability after 18 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.28450484599975545	[201]	[3,61,302]	2	hSpCas9	negative selection	2234165
128254670	128254693	7	+	26627737	HCT116	viability after 18 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	0.41419492233748656	[608]	[407,462,296]	3	hSpCas9	negative selection	2234166
128254413	128254436	7	+	27260157	DLD1	viability	TCCTCCAAACAGAAAGTCACCGG	LEP	ENSG00000174697	0.220101973403354	[]	[]	3	hSpCas9	negative selection	2579017
128254559	128254582	7	-	27260157	DLD1	viability	GAAGATCCCGGAGGTTCTCCAGG	LEP	ENSG00000174697	1.10369974808497	[]	[]	9	hSpCas9	negative selection	2579379
128254431	128254454	7	+	27260157	DLD1	viability	ACCGGTTTGGACTTCATTCCTGG	LEP	ENSG00000174697	1.07030079793526	[]	[]	9	hSpCas9	negative selection	2586875
128254471	128254494	7	-	27260157	DLD1	viability	TGTCTGGTCCATCTTGGATAAGG	LEP	ENSG00000174697	-0.230892570005902	[]	[]	-2	hSpCas9	negative selection	2604494
128254505	128254528	7	-	27260157	DLD1	viability	GCATACTGGTGAGGATCTGTTGG	LEP	ENSG00000174697	-1.61929416682517	[]	[]	-8	hSpCas9	negative selection	2611165
128254475	128254498	7	+	27260157	DLD1	viability	ATCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	0.1974931962584	[]	[]	3	hSpCas9	negative selection	2612454
128254544	128254567	7	-	27260157	DLD1	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	-0.335237133605312	[]	[]	-3	hSpCas9	negative selection	2612591
128254432	128254455	7	-	27260157	DLD1	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.0486270568997261	[]	[]	0	hSpCas9	negative selection	2613931
128254571	128254594	7	+	27260157	DLD1	viability	CCGGGATCTTCTTCACGTGCTGG	LEP	ENSG00000174697	0.261440806722571	[]	[]	4	hSpCas9	negative selection	2614823
128254487	128254510	7	-	27260157	DLD1	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	-0.875660959772245	[]	[]	-6	hSpCas9	negative selection	2614838
128252029	128252052	7	+	27260157	DLD1	viability	GAACCCTGTGCGGATTCTTGTGG	LEP	ENSG00000174697	-2.14520078635413	[]	[]	-9	hSpCas9	negative selection	2615923
128252032	128252055	7	-	27260157	DLD1	viability	AAGCCACAAGAATCCGCACAGGG	LEP	ENSG00000174697	-0.66938573259885	[]	[]	-5	hSpCas9	negative selection	2617743
128254552	128254575	7	+	27260157	DLD1	viability	CCAACGACCTGGAGAACCTCCGG	LEP	ENSG00000174697	0.853399916359566	[]	[]	9	hSpCas9	negative selection	2620883
128254571	128254594	7	-	27260157	DLD1	viability	CCAGCACGTGAAGAAGATCCCGG	LEP	ENSG00000174697	-0.238150074274198	[]	[]	-2	hSpCas9	negative selection	2640885
128254519	128254542	7	-	27260157	DLD1	viability	CACGTTTCTGGAAGGCATACTGG	LEP	ENSG00000174697	0.217372646004624	[]	[]	3	hSpCas9	negative selection	2643812
128254541	128254564	7	+	27260157	DLD1	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.483083762043408	[]	[]	8	hSpCas9	negative selection	2644596
128254600	128254623	7	+	27260157	DLD1	viability	CTAAGAGCTGCCACTTGCCCTGG	LEP	ENSG00000174697	-0.0182897955190693	[]	[]	0	hSpCas9	negative selection	2647047
128254414	128254437	7	-	27260157	DLD1	viability	ACCGGTGACTTTCTGTTTGGAGG	LEP	ENSG00000174697	-0.533537831648438	[]	[]	-4	hSpCas9	negative selection	2648788
128254413	128254436	7	+	27260157	HT1080	viability	TCCTCCAAACAGAAAGTCACCGG	LEP	ENSG00000174697	-0.942213954905634	[]	[]	-8	hSpCas9	negative selection	2655147
128254559	128254582	7	-	27260157	HT1080	viability	GAAGATCCCGGAGGTTCTCCAGG	LEP	ENSG00000174697	1.64578344997232	[]	[]	9	hSpCas9	negative selection	2655509
128254431	128254454	7	+	27260157	HT1080	viability	ACCGGTTTGGACTTCATTCCTGG	LEP	ENSG00000174697	0.759845805301949	[]	[]	6	hSpCas9	negative selection	2663005
128254471	128254494	7	-	27260157	HT1080	viability	TGTCTGGTCCATCTTGGATAAGG	LEP	ENSG00000174697	0.546132868204681	[]	[]	5	hSpCas9	negative selection	2680624
128254505	128254528	7	-	27260157	HT1080	viability	GCATACTGGTGAGGATCTGTTGG	LEP	ENSG00000174697	-0.115301718822901	[]	[]	0	hSpCas9	negative selection	2687295
128254475	128254498	7	+	27260157	HT1080	viability	ATCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	1.08462101303068	[]	[]	8	hSpCas9	negative selection	2688584
128254544	128254567	7	-	27260157	HT1080	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	-1.12303548763868	[]	[]	-8	hSpCas9	negative selection	2688721
128254432	128254455	7	-	27260157	HT1080	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.620045606459338	[]	[]	-8	hSpCas9	negative selection	2690061
128254571	128254594	7	+	27260157	HT1080	viability	CCGGGATCTTCTTCACGTGCTGG	LEP	ENSG00000174697	-0.70742323177099	[]	[]	-8	hSpCas9	negative selection	2690953
128254487	128254510	7	-	27260157	HT1080	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	-0.343853910268368	[]	[]	-7	hSpCas9	negative selection	2690968
128252029	128252052	7	+	27260157	HT1080	viability	GAACCCTGTGCGGATTCTTGTGG	LEP	ENSG00000174697	0.00649824543337705	[]	[]	0	hSpCas9	negative selection	2692053
128252032	128252055	7	-	27260157	HT1080	viability	AAGCCACAAGAATCCGCACAGGG	LEP	ENSG00000174697	0.225761670670389	[]	[]	2	hSpCas9	negative selection	2693873
128254552	128254575	7	+	27260157	HT1080	viability	CCAACGACCTGGAGAACCTCCGG	LEP	ENSG00000174697	1.18250133967559	[]	[]	8	hSpCas9	negative selection	2697013
128254571	128254594	7	-	27260157	HT1080	viability	CCAGCACGTGAAGAAGATCCCGG	LEP	ENSG00000174697	0.603343602848055	[]	[]	5	hSpCas9	negative selection	2717015
128254519	128254542	7	-	27260157	HT1080	viability	CACGTTTCTGGAAGGCATACTGG	LEP	ENSG00000174697	-0.0136941477104229	[]	[]	0	hSpCas9	negative selection	2719942
128254541	128254564	7	+	27260157	HT1080	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.232692159766311	[]	[]	0	hSpCas9	negative selection	2720726
128254600	128254623	7	+	27260157	HT1080	viability	CTAAGAGCTGCCACTTGCCCTGG	LEP	ENSG00000174697	0.658004919206849	[]	[]	6	hSpCas9	negative selection	2723177
128254414	128254437	7	-	27260157	HT1080	viability	ACCGGTGACTTTCTGTTTGGAGG	LEP	ENSG00000174697	0.0269174265063097	[]	[]	0	hSpCas9	negative selection	2724918
128254413	128254436	7	+	27260157	MKN45	viability	TCCTCCAAACAGAAAGTCACCGG	LEP	ENSG00000174697	0.2193624410233	[]	[]	5	hSpCas9	negative selection	2731277
128254559	128254582	7	-	27260157	MKN45	viability	GAAGATCCCGGAGGTTCTCCAGG	LEP	ENSG00000174697	0.611572063183452	[]	[]	7	hSpCas9	negative selection	2731639
128254431	128254454	7	+	27260157	MKN45	viability	ACCGGTTTGGACTTCATTCCTGG	LEP	ENSG00000174697	1.11146864695587	[]	[]	8	hSpCas9	negative selection	2739135
128254471	128254494	7	-	27260157	MKN45	viability	TGTCTGGTCCATCTTGGATAAGG	LEP	ENSG00000174697	-0.0501212252684266	[]	[]	0	hSpCas9	negative selection	2756754
128254505	128254528	7	-	27260157	MKN45	viability	GCATACTGGTGAGGATCTGTTGG	LEP	ENSG00000174697	-0.84647873673172	[]	[]	-7	hSpCas9	negative selection	2763425
128254475	128254498	7	+	27260157	MKN45	viability	ATCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	1.27867376747082	[]	[]	9	hSpCas9	negative selection	2764714
128254544	128254567	7	-	27260157	MKN45	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	-0.221336909494731	[]	[]	-1	hSpCas9	negative selection	2764851
128254432	128254455	7	-	27260157	MKN45	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.487063865813429	[]	[]	6	hSpCas9	negative selection	2766191
128254571	128254594	7	+	27260157	MKN45	viability	CCGGGATCTTCTTCACGTGCTGG	LEP	ENSG00000174697	0.702317348023029	[]	[]	7	hSpCas9	negative selection	2767083
128254487	128254510	7	-	27260157	MKN45	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	1.15940267928123	[]	[]	8	hSpCas9	negative selection	2767098
128252029	128252052	7	+	27260157	MKN45	viability	GAACCCTGTGCGGATTCTTGTGG	LEP	ENSG00000174697	-0.813120799799952	[]	[]	-7	hSpCas9	negative selection	2768183
128252032	128252055	7	-	27260157	MKN45	viability	AAGCCACAAGAATCCGCACAGGG	LEP	ENSG00000174697	-0.923269292062343	[]	[]	-7	hSpCas9	negative selection	2770003
128254552	128254575	7	+	27260157	MKN45	viability	CCAACGACCTGGAGAACCTCCGG	LEP	ENSG00000174697	0.918072514156816	[]	[]	8	hSpCas9	negative selection	2773143
128254571	128254594	7	-	27260157	MKN45	viability	CCAGCACGTGAAGAAGATCCCGG	LEP	ENSG00000174697	-0.00918281737871904	[]	[]	0	hSpCas9	negative selection	2793145
128254519	128254542	7	-	27260157	MKN45	viability	CACGTTTCTGGAAGGCATACTGG	LEP	ENSG00000174697	-0.367865846327272	[]	[]	-1	hSpCas9	negative selection	2796072
128254541	128254564	7	+	27260157	MKN45	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.688899543119836	[]	[]	-7	hSpCas9	negative selection	2796856
128254600	128254623	7	+	27260157	MKN45	viability	CTAAGAGCTGCCACTTGCCCTGG	LEP	ENSG00000174697	0.534043991334447	[]	[]	6	hSpCas9	negative selection	2799307
128254414	128254437	7	-	27260157	MKN45	viability	ACCGGTGACTTTCTGTTTGGAGG	LEP	ENSG00000174697	0.297329303494836	[]	[]	5	hSpCas9	negative selection	2801048
128254413	128254436	7	+	27260157	RKO	viability	TCCTCCAAACAGAAAGTCACCGG	LEP	ENSG00000174697	-1.25298718719066	[]	[]	-8	hSpCas9	negative selection	2807407
128254559	128254582	7	-	27260157	RKO	viability	GAAGATCCCGGAGGTTCTCCAGG	LEP	ENSG00000174697	0.146586330706876	[]	[]	0	hSpCas9	negative selection	2807769
128254431	128254454	7	+	27260157	RKO	viability	ACCGGTTTGGACTTCATTCCTGG	LEP	ENSG00000174697	-0.10895955864466	[]	[]	0	hSpCas9	negative selection	2815265
128254471	128254494	7	-	27260157	RKO	viability	TGTCTGGTCCATCTTGGATAAGG	LEP	ENSG00000174697	-0.311814258678284	[]	[]	-6	hSpCas9	negative selection	2832884
128254505	128254528	7	-	27260157	RKO	viability	GCATACTGGTGAGGATCTGTTGG	LEP	ENSG00000174697	0.0950588990851613	[]	[]	0	hSpCas9	negative selection	2839555
128254475	128254498	7	+	27260157	RKO	viability	ATCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	0.221663263107123	[]	[]	1	hSpCas9	negative selection	2840844
128254544	128254567	7	-	27260157	RKO	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	-0.834990829870021	[]	[]	-7	hSpCas9	negative selection	2840981
128254432	128254455	7	-	27260157	RKO	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.0708619825956535	[]	[]	0	hSpCas9	negative selection	2842321
128254571	128254594	7	+	27260157	RKO	viability	CCGGGATCTTCTTCACGTGCTGG	LEP	ENSG00000174697	-0.748360415033834	[]	[]	-7	hSpCas9	negative selection	2843213
128254487	128254510	7	-	27260157	RKO	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	-0.312503745755285	[]	[]	-6	hSpCas9	negative selection	2843228
128252029	128252052	7	+	27260157	RKO	viability	GAACCCTGTGCGGATTCTTGTGG	LEP	ENSG00000174697	-0.478084494741121	[]	[]	-6	hSpCas9	negative selection	2844313
128252032	128252055	7	-	27260157	RKO	viability	AAGCCACAAGAATCCGCACAGGG	LEP	ENSG00000174697	-0.840477405740281	[]	[]	-7	hSpCas9	negative selection	2846133
128254552	128254575	7	+	27260157	RKO	viability	CCAACGACCTGGAGAACCTCCGG	LEP	ENSG00000174697	0.407489822196639	[]	[]	2	hSpCas9	negative selection	2849273
128254571	128254594	7	-	27260157	RKO	viability	CCAGCACGTGAAGAAGATCCCGG	LEP	ENSG00000174697	-0.553026208875152	[]	[]	-7	hSpCas9	negative selection	2869275
128254519	128254542	7	-	27260157	RKO	viability	CACGTTTCTGGAAGGCATACTGG	LEP	ENSG00000174697	-0.842790809300167	[]	[]	-7	hSpCas9	negative selection	2872202
128254541	128254564	7	+	27260157	RKO	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.657476361792763	[]	[]	-7	hSpCas9	negative selection	2872986
128254600	128254623	7	+	27260157	RKO	viability	CTAAGAGCTGCCACTTGCCCTGG	LEP	ENSG00000174697	-0.253418971173122	[]	[]	-1	hSpCas9	negative selection	2875437
128254414	128254437	7	-	27260157	RKO	viability	ACCGGTGACTTTCTGTTTGGAGG	LEP	ENSG00000174697	-0.0115741995212992	[]	[]	0	hSpCas9	negative selection	2877178
128254413	128254436	7	+	27260157	SF268	viability	TCCTCCAAACAGAAAGTCACCGG	LEP	ENSG00000174697	-0.133352200738092	[]	[]	-1	hSpCas9	negative selection	2883537
128254559	128254582	7	-	27260157	SF268	viability	GAAGATCCCGGAGGTTCTCCAGG	LEP	ENSG00000174697	1.30458447549635	[]	[]	9	hSpCas9	negative selection	2883899
128254431	128254454	7	+	27260157	SF268	viability	ACCGGTTTGGACTTCATTCCTGG	LEP	ENSG00000174697	1.05359039807489	[]	[]	9	hSpCas9	negative selection	2891395
128254471	128254494	7	-	27260157	SF268	viability	TGTCTGGTCCATCTTGGATAAGG	LEP	ENSG00000174697	0.201101052118031	[]	[]	3	hSpCas9	negative selection	2909014
128254505	128254528	7	-	27260157	SF268	viability	GCATACTGGTGAGGATCTGTTGG	LEP	ENSG00000174697	0.275719201774213	[]	[]	4	hSpCas9	negative selection	2915685
128254475	128254498	7	+	27260157	SF268	viability	ATCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	1.20410617981189	[]	[]	9	hSpCas9	negative selection	2916974
128254544	128254567	7	-	27260157	SF268	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.30326791504703	[]	[]	4	hSpCas9	negative selection	2917111
128254432	128254455	7	-	27260157	SF268	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.774429935197671	[]	[]	8	hSpCas9	negative selection	2918451
128254571	128254594	7	+	27260157	SF268	viability	CCGGGATCTTCTTCACGTGCTGG	LEP	ENSG00000174697	0.121050408198708	[]	[]	0	hSpCas9	negative selection	2919343
128254487	128254510	7	-	27260157	SF268	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.62864765270748	[]	[]	8	hSpCas9	negative selection	2919358
128252029	128252052	7	+	27260157	SF268	viability	GAACCCTGTGCGGATTCTTGTGG	LEP	ENSG00000174697	0.264411059159803	[]	[]	4	hSpCas9	negative selection	2920443
128252032	128252055	7	-	27260157	SF268	viability	AAGCCACAAGAATCCGCACAGGG	LEP	ENSG00000174697	0.868785663869397	[]	[]	9	hSpCas9	negative selection	2922263
128254552	128254575	7	+	27260157	SF268	viability	CCAACGACCTGGAGAACCTCCGG	LEP	ENSG00000174697	1.04407494535866	[]	[]	9	hSpCas9	negative selection	2925403
128254571	128254594	7	-	27260157	SF268	viability	CCAGCACGTGAAGAAGATCCCGG	LEP	ENSG00000174697	0.877546288483792	[]	[]	9	hSpCas9	negative selection	2945405
128254519	128254542	7	-	27260157	SF268	viability	CACGTTTCTGGAAGGCATACTGG	LEP	ENSG00000174697	-0.845555713897348	[]	[]	-6	hSpCas9	negative selection	2948332
128254541	128254564	7	+	27260157	SF268	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.116478935401009	[]	[]	0	hSpCas9	negative selection	2949116
128254600	128254623	7	+	27260157	SF268	viability	CTAAGAGCTGCCACTTGCCCTGG	LEP	ENSG00000174697	0.62498415315569	[]	[]	8	hSpCas9	negative selection	2951567
128254414	128254437	7	-	27260157	SF268	viability	ACCGGTGACTTTCTGTTTGGAGG	LEP	ENSG00000174697	0.590363614756363	[]	[]	8	hSpCas9	negative selection	2953308
128252032	128252055	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGCCACAAGAATCCGCACAGGG	LEP	ENSG00000174697	0.28602395881280995	[3,2]	[3,3]	6	hSpCas9	positive selection	2999235
128252142	128252165	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATCAATGACATTTCACACACGG	LEP	ENSG00000174697	-0.3226491373870576	[4,3]	[2,2]	-4	hSpCas9	positive selection	2999236
128252058	128252081	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTGGACATAGAAAAGATAGGG	LEP	ENSG00000174697	-0.4005051281544169	[2,2]	[2,0]	-5	hSpCas9	positive selection	2999237
128252116	128252139	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-1.2298415004628325	[3,3]	[1,0]	-9	hSpCas9	positive selection	2999238
128252032	128252055	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGCCACAAGAATCCGCACAGGG	LEP	ENSG00000174697	-0.06333607170294381	[3,3]	[3,0]	-1	hSpCas9	positive selection	3067093
128252142	128252165	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATCAATGACATTTCACACACGG	LEP	ENSG00000174697	0.093515874505535	[4,4]	[3,2]	1	hSpCas9	positive selection	3067094
128252058	128252081	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTGGACATAGAAAAGATAGGG	LEP	ENSG00000174697	0.32740705507584206	[2,2]	[2,2]	6	hSpCas9	positive selection	3067095
128252116	128252139	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.4140353969904266	[3,3]	[7,0]	7	hSpCas9	positive selection	3067096
128252033	128252056		-	24336571	A375	resistance to PLX after 7 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.13982512035917827	[5,3]	[4,3]	-4	hSpCas9	positive selection	3124459
128254541	128254564		+	24336571	A375	resistance to PLX after 7 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.01737778922124633	[2,2]	[2,1]	0	hSpCas9	positive selection	3124460
128252137	128252160		-	24336571	A375	resistance to PLX after 7 days	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	-0.18212001067705888	[15,11]	[11,11]	-6	hSpCas9	positive selection	3124461
128254487	128254510		-	24336571	A375	resistance to PLX after 7 days	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	-0.29958860395300957	[25,24]	[18,21]	-8	hSpCas9	positive selection	3124462
128252033	128252056		-	24336571	A375	resistance to PLX after 14 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.05835648974721863	[4,5]	[1,1]	0	hSpCas9	positive selection	3182252
128254541	128254564		+	24336571	A375	resistance to PLX after 14 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	1.342818793274956	[1,1]	[1,3]	8	hSpCas9	positive selection	3182253
128252137	128252160		-	24336571	A375	resistance to PLX after 14 days	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	-0.15207202516563564	[10,10]	[4,3]	-1	hSpCas9	positive selection	3182254
128254487	128254510		-	24336571	A375	resistance to PLX after 14 days	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	-0.7201389270696921	[27,22]	[5,7]	-8	hSpCas9	positive selection	3182255
128252033	128252056		-	24336571	A375	viability after 7 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.6256847961955021	[8]	[5,3]	-7	hSpCas9	negative selection	3240045
128254541	128254564		+	24336571	A375	viability after 7 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-1.1512202141929255	[6]	[2,2]	-9	hSpCas9	negative selection	3240046
128252137	128252160		-	24336571	A375	viability after 7 days	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.2512982070692162	[11]	[15,11]	4	hSpCas9	negative selection	3240047
128254487	128254510		-	24336571	A375	viability after 7 days	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.7154866769151622	[15]	[25,24]	9	hSpCas9	negative selection	3240048
128252033	128252056		-	24336571	A375	viability after 14 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.5361545881499075	[8]	[4,5]	-6	hSpCas9	negative selection	3297838
128254541	128254564		+	24336571	A375	viability after 14 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-1.4249145974553357	[6]	[1,1]	-9	hSpCas9	negative selection	3297839
128252137	128252160		-	24336571	A375	viability after 14 days	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	-0.003930997035298478	[11]	[10,10]	0	hSpCas9	negative selection	3297840
128254487	128254510		-	24336571	A375	viability after 14 days	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.7418481722411923	[15]	[27,22]	8	hSpCas9	negative selection	3297841
128252119	128252142	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-1.8327862082184536	[544,544]	[0,0]	-9	hSpCas9	positive selection	3377014
128254544	128254567	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	-0.2818325996621964	[185,185]	[0,0]	-2	hSpCas9	positive selection	3377015
128254432	128254455	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.11777485904704146	[140,140]	[0,0]	0	hSpCas9	positive selection	3377016
128252032	128252055	7	-	26780180	HT29	viability (Avana library 4 designs)	AAGCCACAAGAATCCGCACAGGG	LEP	ENSG00000174697	1.27017852855352	[]	[]	5	hSpCas9	negative selection	3436778
128252141	128252164	7	+	26780180	HT29	viability (Avana library 4 designs)	GATCAATGACATTTCACACACGG	LEP	ENSG00000174697	1.57825876926634	[]	[]	6	hSpCas9	negative selection	3436779
128252058	128252081	7	-	26780180	HT29	viability (Avana library 4 designs)	GCTTGGACATAGAAAAGATAGGG	LEP	ENSG00000174697	0.621788768672192	[]	[]	2	hSpCas9	negative selection	3436780
128252116	128252139	7	-	26780180	HT29	viability (Avana library 4 designs)	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.950987265588548	[]	[]	3	hSpCas9	negative selection	3436781
128252032	128252055	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAGCCACAAGAATCCGCACAGGG	LEP	ENSG00000174697	0.394492696535373	[]	[]	0	hSpCas9	negative selection	3525162
128252058	128252081	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTGGACATAGAAAAGATAGGG	LEP	ENSG00000174697	-4.86949360866282	[]	[]	-5	hSpCas9	negative selection	3525163
128252141	128252164	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATCAATGACATTTCACACACGG	LEP	ENSG00000174697	-6.70243971788349	[]	[]	-6	hSpCas9	negative selection	3525164
128252116	128252139	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-4.39452830872262	[]	[]	-5	hSpCas9	negative selection	3525165
128252119	128252142	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.738568325639744	[]	[]	-1	hSpCas9	negative selection	3525166
128254460	128254483	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	3.96648307679192	[]	[]	6	hSpCas9	negative selection	3525167
128252032	128252055	7	-	26780180	A375	viability (Avana lentiGuide)	AAGCCACAAGAATCCGCACAGGG	LEP	ENSG00000174697	9.09582862268231	[]	[]	6	hSpCas9	negative selection	3633821
128252058	128252081	7	-	26780180	A375	viability (Avana lentiGuide)	GCTTGGACATAGAAAAGATAGGG	LEP	ENSG00000174697	-1.02288914953039	[]	[]	-2	hSpCas9	negative selection	3633822
128252141	128252164	7	+	26780180	A375	viability (Avana lentiGuide)	GATCAATGACATTTCACACACGG	LEP	ENSG00000174697	-3.39617117750181	[]	[]	-6	hSpCas9	negative selection	3633823
128252116	128252139	7	-	26780180	A375	viability (Avana lentiGuide)	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	2.47964009774097	[]	[]	2	hSpCas9	negative selection	3633824
128252119	128252142	7	+	26780180	A375	viability (Avana lentiGuide)	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-2.74589503085797	[]	[]	-5	hSpCas9	negative selection	3633825
128254460	128254483	7	-	26780180	A375	viability (Avana lentiGuide)	TCTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	-1.29400577013254	[]	[]	-2	hSpCas9	negative selection	3633826
128252032	128252055	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGCCACAAGAATCCGCACAGGG	LEP	ENSG00000174697	-0.026466164671824693	[4]	[5,3]	0	hSpCas9	positive selection	3742480
128252058	128252081	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTGGACATAGAAAAGATAGGG	LEP	ENSG00000174697	-0.19442456885700163	[4]	[4,3]	-3	hSpCas9	positive selection	3742481
128252141	128252164	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCAATGACATTTCACACACGG	LEP	ENSG00000174697	-0.8581358215412564	[6]	[3,2]	-8	hSpCas9	positive selection	3742482
128252116	128252139	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-0.0077087001901746804	[4]	[3,5]	0	hSpCas9	positive selection	3742483
128252119	128252142	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.11129774548088565	[5]	[4,4]	-2	hSpCas9	positive selection	3742484
128254460	128254483	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	0.221863769644229	[5]	[5,5]	6	hSpCas9	positive selection	3742485
128252032	128252055	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGCCACAAGAATCCGCACAGGG	LEP	ENSG00000174697	-0.2085004137707084	[5]	[3,3]	-3	hSpCas9	positive selection	3851087
128252058	128252081	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTGGACATAGAAAAGATAGGG	LEP	ENSG00000174697	-0.4191904048985493	[3]	[2,1]	-5	hSpCas9	positive selection	3851088
128252141	128252164	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCAATGACATTTCACACACGG	LEP	ENSG00000174697	0.1987133879369254	[5]	[6,4]	5	hSpCas9	positive selection	3851089
128252116	128252139	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-0.1804365634811666	[5]	[3,3]	-2	hSpCas9	positive selection	3851090
128252119	128252142	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.30784110423298355	[6]	[6,6]	8	hSpCas9	positive selection	3851091
128254460	128254483	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	0.23091189807240975	[5]	[5,5]	6	hSpCas9	positive selection	3851092
128252033	128252056	7	-	26780180	A375	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.901495528487912	[]	[]	4	hSpCas9	negative selection	3956774
128254432	128254455	7	-	26780180	A375	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	1.07904038733336	[]	[]	5	hSpCas9	negative selection	3956775
128254541	128254564	7	+	26780180	A375	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	1.73219163265629	[]	[]	9	hSpCas9	negative selection	3956776
128254487	128254510	7	-	26780180	A375	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	1.14499016084869	[]	[]	6	hSpCas9	negative selection	3956777
128252119	128252142	7	+	26780180	A375	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.690971717505754	[]	[]	2	hSpCas9	negative selection	3956778
128254544	128254567	7	-	26780180	A375	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	1.31580473683218	[]	[]	7	hSpCas9	negative selection	3956779
128252033	128252056	7	-	26780180	HT29	viability (GeCKOv2 library)	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	1.54893846151851	[]	[]	7	hSpCas9	negative selection	4064740
128254432	128254455	7	-	26780180	HT29	viability (GeCKOv2 library)	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	1.44754053567384	[]	[]	7	hSpCas9	negative selection	4064741
128254541	128254564	7	+	26780180	HT29	viability (GeCKOv2 library)	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	2.04116871891766	[]	[]	9	hSpCas9	negative selection	4064742
128254487	128254510	7	-	26780180	HT29	viability (GeCKOv2 library)	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	1.75736992506634	[]	[]	8	hSpCas9	negative selection	4064743
128252119	128252142	7	+	26780180	HT29	viability (GeCKOv2 library)	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.583232669257471	[]	[]	2	hSpCas9	negative selection	4064744
128254544	128254567	7	-	26780180	HT29	viability (GeCKOv2 library)	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.824623879175157	[]	[]	3	hSpCas9	negative selection	4064745
128252033	128252056	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.5758630531676665	[2]	[0,0]	-9	hSpCas9	positive selection	4148497
128254541	128254564	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.36621792212563054	[1]	[0,0]	-7	hSpCas9	positive selection	4148498
128252137	128252160	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	-0.21366953949780507	[3]	[1,1]	-5	hSpCas9	positive selection	4148499
128254487	128254510	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.06751743527438528	[3]	[2,2]	1	hSpCas9	positive selection	4148500
128252033	128252056	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.42525606002607924	[1]	[2,0,0,0]	3	hSpCas9	positive selection	4212519
128254541	128254564	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.051247283410847944	[2]	[1,1,0,0]	0	hSpCas9	positive selection	4212520
128252137	128252160	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.3239883560082649	[2]	[1,2,2,0]	2	hSpCas9	positive selection	4212521
128254487	128254510	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.680901276694503	[3]	[2,3,3,1]	4	hSpCas9	positive selection	4212522
128254541	128254564	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.4744991464405041	[2]	[1,0]	-8	hSpCas9	positive selection	4279979
128252033	128252056	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.45227856603768735	[1]	[0,0]	-7	hSpCas9	positive selection	4279980
128254487	128254510	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.5056640857863206	[3]	[2,4]	9	hSpCas9	positive selection	4279981
128252119	128252142	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.23156782291404115	[4]	[4,4]	4	hSpCas9	positive selection	4344235
128254544	128254567	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.32105122854230006	[2]	[3,2]	6	hSpCas9	positive selection	4344236
128254432	128254455	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.13940072050967567	[2]	[2,0]	-3	hSpCas9	positive selection	4344237
128252116	128252138	7	-	27760321	OCIAML3	viability	GTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	1.4096823703696093	[96,82]	[152,229]	9	hSpCas9	negative selection	4414196
128252147	128252169	7	+	27760321	OCIAML3	viability	TGACATTTCACACACGGTAAGG	LEP	ENSG00000174697	-0.43474222864662293	[330,270]	[92,277]	-4	hSpCas9	negative selection	4414197
128254432	128254454	7	-	27760321	OCIAML3	viability	CCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.3648715323825018	[159,114]	[86,76]	-4	hSpCas9	negative selection	4414198
128254460	128254482	7	-	27760321	OCIAML3	viability	CTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	0.36648459973200925	[481,397]	[448,431]	4	hSpCas9	negative selection	4414199
128254476	128254498	7	+	27760321	OCIAML3	viability	TCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	0.5009237521148391	[326,283]	[203,510]	6	hSpCas9	negative selection	4414200
128252116	128252138	7	-	27760321	OCIAML2	viability	GTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	1.15766629991893	[96,82]	[151,174]	9	hSpCas9	negative selection	4497659
128252147	128252169	7	+	27760321	OCIAML2	viability	TGACATTTCACACACGGTAAGG	LEP	ENSG00000174697	-0.9896995698840825	[330,270]	[118,125]	-7	hSpCas9	negative selection	4497660
128254432	128254454	7	-	27760321	OCIAML2	viability	CCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.42592682823982964	[159,114]	[159,131]	6	hSpCas9	negative selection	4497661
128254460	128254482	7	-	27760321	OCIAML2	viability	CTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	0.22155262661926606	[481,397]	[309,548]	3	hSpCas9	negative selection	4497662
128254476	128254498	7	+	27760321	OCIAML2	viability	TCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	0.3450005277042003	[326,283]	[253,390]	5	hSpCas9	negative selection	4497663
128252116	128252138	7	-	27760321	MV411	viability	GTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.6098628183887969	[96,82]	[37,168]	4	hSpCas9	negative selection	4581122
128252147	128252169	7	+	27760321	MV411	viability	TGACATTTCACACACGGTAAGG	LEP	ENSG00000174697	-0.16462904113117616	[330,270]	[105,281]	-1	hSpCas9	negative selection	4581123
128254432	128254454	7	-	27760321	MV411	viability	CCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	1.6592100071724358	[159,114]	[375,144]	9	hSpCas9	negative selection	4581124
128254460	128254482	7	-	27760321	MV411	viability	CTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	0.9526017176478928	[481,397]	[542,583]	7	hSpCas9	negative selection	4581125
128254476	128254498	7	+	27760321	MV411	viability	TCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	0.4298968094706598	[326,283]	[397,79]	3	hSpCas9	negative selection	4581126
128252116	128252138	7	-	27760321	HL60	viability	GTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-0.07337019250711219	[96,82]	[107,28]	-1	hSpCas9	negative selection	4664585
128252147	128252169	7	+	27760321	HL60	viability	TGACATTTCACACACGGTAAGG	LEP	ENSG00000174697	-0.5961831971166454	[330,270]	[156,166]	-6	hSpCas9	negative selection	4664586
128254432	128254454	7	-	27760321	HL60	viability	CCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.17278249721569816	[159,114]	[102,148]	2	hSpCas9	negative selection	4664587
128254460	128254482	7	-	27760321	HL60	viability	CTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	-0.5016473539700325	[481,397]	[242,262]	-5	hSpCas9	negative selection	4664588
128254476	128254498	7	+	27760321	HL60	viability	TCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	-0.16672670867670736	[326,283]	[213,229]	-2	hSpCas9	negative selection	4664589
128252116	128252138	7	-	27760321	HT1080	viability	GTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	2.5548646449890247	[82,64]	[241,97]	9	hSpCas9	negative selection	4748048
128252147	128252169	7	+	27760321	HT1080	viability	TGACATTTCACACACGGTAAGG	LEP	ENSG00000174697	-1.9870629886800995	[270,211]	[29,17]	-6	hSpCas9	negative selection	4748049
128254432	128254454	7	-	27760321	HT1080	viability	CCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-1.6065471359918126	[114,89]	[0,26]	-5	hSpCas9	negative selection	4748050
128254460	128254482	7	-	27760321	HT1080	viability	CTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	1.0867687423913592	[397,310]	[309,288]	6	hSpCas9	negative selection	4748051
128254476	128254498	7	+	27760321	HT1080	viability	TCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	-1.9550703912738143	[283,221]	[46,2]	-6	hSpCas9	negative selection	4748052
128252116	128252138	7	-	27760321	HT29	viability after 7 days	GTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-0.5302691967222266	[82,64]	[59,78,57]	-6	hSpCas9	negative selection	4831511
128252147	128252169	7	+	27760321	HT29	viability after 7 days	TGACATTTCACACACGGTAAGG	LEP	ENSG00000174697	0.03521550019462094	[270,211]	[431,206,330]	0	hSpCas9	negative selection	4831512
128254432	128254454	7	-	27760321	HT29	viability after 7 days	CCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.6922462197851846	[114,89]	[169,233,227]	9	hSpCas9	negative selection	4831513
128254460	128254482	7	-	27760321	HT29	viability after 7 days	CTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	0.04703099113296294	[397,310]	[534,439,446]	0	hSpCas9	negative selection	4831514
128254476	128254498	7	+	27760321	HT29	viability after 7 days	TCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	0.003659371182820337	[283,221]	[371,365,248]	0	hSpCas9	negative selection	4831515
128252116	128252138	7	-	27760321	HT29	viability after 25 days	GTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-0.6205883855650955	[82,64]	[74,56,28]	-5	hSpCas9	negative selection	4914974
128252147	128252169	7	+	27760321	HT29	viability after 25 days	TGACATTTCACACACGGTAAGG	LEP	ENSG00000174697	0.2401630181852299	[270,211]	[486,97,388]	2	hSpCas9	negative selection	4914975
128254432	128254454	7	-	27760321	HT29	viability after 25 days	CCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.9768491611063932	[114,89]	[118,300,283]	9	hSpCas9	negative selection	4914976
128254460	128254482	7	-	27760321	HT29	viability after 25 days	CTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	0.1461760655875774	[397,310]	[424,393,535]	1	hSpCas9	negative selection	4914977
128254476	128254498	7	+	27760321	HT29	viability after 25 days	TCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	0.5229720643053726	[283,221]	[478,397,358]	6	hSpCas9	negative selection	4914978
128252116	128252138	7	-	27760321	HT29	viability after 22 days	GTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-0.2400317697924952	[82,64]	[110,64,39]	-2	hSpCas9	negative selection	4998437
128252147	128252169	7	+	27760321	HT29	viability after 22 days	TGACATTTCACACACGGTAAGG	LEP	ENSG00000174697	-0.07419611302908247	[270,211]	[252,173,369]	-1	hSpCas9	negative selection	4998438
128254432	128254454	7	-	27760321	HT29	viability after 22 days	CCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	1.2192720987239443	[114,89]	[160,279,390]	9	hSpCas9	negative selection	4998439
128254460	128254482	7	-	27760321	HT29	viability after 22 days	CTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	0.20999754365898757	[397,310]	[472,601,345]	2	hSpCas9	negative selection	4998440
128254476	128254498	7	+	27760321	HT29	viability after 22 days	TCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	-0.027339673691951227	[283,221]	[212,262,387]	0	hSpCas9	negative selection	4998441
128252116	128252138	7	-	27760321	HT29	viability after 19 days	GTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.5845650595908902	[82,64]	[94,278,7]	6	hSpCas9	negative selection	5081900
128252147	128252169	7	+	27760321	HT29	viability after 19 days	TGACATTTCACACACGGTAAGG	LEP	ENSG00000174697	0.8265369466563299	[270,211]	[197,488,741]	8	hSpCas9	negative selection	5081901
128254432	128254454	7	-	27760321	HT29	viability after 19 days	CCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.6396496230583626	[114,89]	[27,409,96]	6	hSpCas9	negative selection	5081902
128254460	128254482	7	-	27760321	HT29	viability after 19 days	CTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	0.3297713020910933	[397,310]	[682,257,601]	3	hSpCas9	negative selection	5081903
128254476	128254498	7	+	27760321	HT29	viability after 19 days	TCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	0.15873646661487328	[283,221]	[453,269,260]	1	hSpCas9	negative selection	5081904
128252116	128252138	7	-	27760321	HT29	viability after 16 days	GTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-0.06416699089457101	[82,64]	[198,37,12]	0	hSpCas9	negative selection	5165363
128252147	128252169	7	+	27760321	HT29	viability after 16 days	TGACATTTCACACACGGTAAGG	LEP	ENSG00000174697	-0.08203114394686062	[270,211]	[302,191,276]	-1	hSpCas9	negative selection	5165364
128254432	128254454	7	-	27760321	HT29	viability after 16 days	CCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	1.1887925872986074	[114,89]	[208,314,253]	9	hSpCas9	negative selection	5165365
128254460	128254482	7	-	27760321	HT29	viability after 16 days	CTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	0.16138995821022495	[397,310]	[473,465,392]	1	hSpCas9	negative selection	5165366
128254476	128254498	7	+	27760321	HT29	viability after 16 days	TCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	0.9378966781962318	[283,221]	[519,685,414]	9	hSpCas9	negative selection	5165367
128252116	128252138	7	-	27760321	HT29	viability after 13 days	GTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-1.3834311554017247	[82,64]	[23,28,44]	-8	hSpCas9	negative selection	5248826
128252147	128252169	7	+	27760321	HT29	viability after 13 days	TGACATTTCACACACGGTAAGG	LEP	ENSG00000174697	-0.0762902488966628	[270,211]	[292,268,236]	-1	hSpCas9	negative selection	5248827
128254432	128254454	7	-	27760321	HT29	viability after 13 days	CCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.029737049768497004	[114,89]	[73,148,125]	0	hSpCas9	negative selection	5248828
128254460	128254482	7	-	27760321	HT29	viability after 13 days	CTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	-0.05885825243105052	[397,310]	[445,490,255]	0	hSpCas9	negative selection	5248829
128254476	128254498	7	+	27760321	HT29	viability after 13 days	TCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	0.42492065868372697	[283,221]	[431,286,458]	5	hSpCas9	negative selection	5248830
128252116	128252138	7	-	27760321	HT29	viability after 10 days	GTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-0.4333346232656661	[82,64]	[111,42,49]	-5	hSpCas9	negative selection	5332289
128252147	128252169	7	+	27760321	HT29	viability after 10 days	TGACATTTCACACACGGTAAGG	LEP	ENSG00000174697	-0.460407857578503	[270,211]	[199,237,219]	-5	hSpCas9	negative selection	5332290
128254432	128254454	7	-	27760321	HT29	viability after 10 days	CCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.904910085741353	[114,89]	[191,401,131]	9	hSpCas9	negative selection	5332291
128254460	128254482	7	-	27760321	HT29	viability after 10 days	CTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	-0.0935754047001543	[397,310]	[272,528,444]	-1	hSpCas9	negative selection	5332292
128254476	128254498	7	+	27760321	HT29	viability after 10 days	TCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	0.8449925133409439	[283,221]	[406,973,337]	9	hSpCas9	negative selection	5332293
128252116	128252138	7	-	27760321	MOLM13	viability	GTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-2.8588423292098146	[96,82]	[13,0]	-8	hSpCas9	negative selection	5415752
128252147	128252169	7	+	27760321	MOLM13	viability	TGACATTTCACACACGGTAAGG	LEP	ENSG00000174697	0.055878680295058325	[330,270]	[159,188]	0	hSpCas9	negative selection	5415753
128254432	128254454	7	-	27760321	MOLM13	viability	CCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	1.7787016042424233	[159,114]	[404,142]	9	hSpCas9	negative selection	5415754
128254460	128254482	7	-	27760321	MOLM13	viability	CTTGGATAAGGTCAGGATGGGG	LEP	ENSG00000174697	0.4658673434089083	[481,397]	[464,235]	3	hSpCas9	negative selection	5415755
128254476	128254498	7	+	27760321	MOLM13	viability	TCCAAGATGGACCAGACACTGG	LEP	ENSG00000174697	1.0301137382242451	[326,283]	[362,340]	7	hSpCas9	negative selection	5415756
128241290	128241313	7	+	27661255	K562	viability	GCGCCAGCGGTTGCAAGGTAAGG	LEP	ENSG00000174697	0.10093283032381684	[300,297]	[254,257]	3	dCas9-KRAB	negative selection	5490093
128241296	128241319	7	+	27661255	K562	viability	GCGGTTGCAAGGTAAGGCCCCGG	LEP	ENSG00000174697	-0.07894471351849819	[321,340]	[230,266]	-3	dCas9-KRAB	negative selection	5490094
128241661	128241684	7	+	27661255	K562	viability	GTCTGAAGGAGATAAAGTTGGGG	LEP	ENSG00000174697	0.1792005877990154	[552,634]	[489,574]	6	dCas9-KRAB	negative selection	5490095
128254541	128254564	7	+	27260156	BXPC3	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.5350068860693697	[308]	[164,159,303,279]	-8	hSpCas9	negative selection	5552439
128252033	128252056	7	-	27260156	BXPC3	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.32687322121893847	[97]	[121,121,170,95]	7	hSpCas9	negative selection	5552440
128254487	128254510	7	-	27260156	BXPC3	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.45839725512820106	[675]	[898,932,962,1109]	8	hSpCas9	negative selection	5552441
128252119	128252142	7	+	27260156	BXPC3	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.013992295384133602	[1583]	[1472,1682,1615,1813]	0	hSpCas9	negative selection	5616695
128254544	128254567	7	-	27260156	BXPC3	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.3086112642666369	[425]	[549,494,579,585]	6	hSpCas9	negative selection	5616696
128254432	128254455	7	-	27260156	BXPC3	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.16240540513568819	[300]	[348,301,338,428]	3	hSpCas9	negative selection	5616697
128254541	128254564	7	+	27260156	A673	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.07779411262395242	[308]	[436,186,323,478]	-2	hSpCas9	negative selection	5673690
128252033	128252056	7	-	27260156	A673	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.06606915977029626	[97]	[166,112,95,121]	1	hSpCas9	negative selection	5673691
128254487	128254510	7	-	27260156	A673	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.42446496263997224	[675]	[1418,940,896,1144]	8	hSpCas9	negative selection	5673692
128252119	128252142	7	+	27260156	A673	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.02697723395749052	[1583]	[2088,1654,1856,1894]	0	hSpCas9	negative selection	5737946
128254544	128254567	7	-	27260156	A673	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.04088292404366871	[425]	[467,562,567,494]	1	hSpCas9	negative selection	5737947
128254432	128254455	7	-	27260156	A673	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.24048388462928755	[300]	[593,389,306,437]	5	hSpCas9	negative selection	5737948
128254541	128254564	7	+	27260156	A375	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.35750095891773614	[308]	[292,329,324,194]	-5	hSpCas9	negative selection	5794941
128252033	128252056	7	-	27260156	A375	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.5091850139340452	[97]	[158,275,163,77]	7	hSpCas9	negative selection	5794942
128254487	128254510	7	-	27260156	A375	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.29226002661890227	[675]	[875,975,1125,894]	4	hSpCas9	negative selection	5794943
128252119	128252142	7	+	27260156	A375	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.23654614809183316	[1583]	[2243,2559,2105,1888]	3	hSpCas9	negative selection	5859197
128254544	128254567	7	-	27260156	A375	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.19630058710688847	[425]	[510,814,491,501]	3	hSpCas9	negative selection	5859198
128254432	128254455	7	-	27260156	A375	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.04329520046519886	[300]	[360,514,265,255]	0	hSpCas9	negative selection	5859199
128254541	128254564	7	+	27260156	COLO741	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.5536561958252306	[308]	[234,124,430]	-8	hSpCas9	negative selection	5916192
128252033	128252056	7	-	27260156	COLO741	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.6265293119432362	[97]	[139,128,297]	9	hSpCas9	negative selection	5916193
128254487	128254510	7	-	27260156	COLO741	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.17382426671152118	[675]	[1073,935,922]	3	hSpCas9	negative selection	5916194
128252119	128252142	7	+	27260156	COLO741	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.007786929415932287	[1583]	[2214,1806,2027]	0	hSpCas9	negative selection	5980448
128254544	128254567	7	-	27260156	COLO741	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	-0.1658897445120334	[425]	[611,493,367]	-4	hSpCas9	negative selection	5980449
128254432	128254455	7	-	27260156	COLO741	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.1873898231864951	[300]	[425,300,295]	-4	hSpCas9	negative selection	5980450
128254541	128254564	7	+	27260156	CAL120	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.13684281416179056	[308]	[314,278,447]	-2	hSpCas9	negative selection	6037443
128252033	128252056	7	-	27260156	CAL120	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	1.9465861188489773	[97]	[163,116,1071]	9	hSpCas9	negative selection	6037444
128254487	128254510	7	-	27260156	CAL120	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.5602338656924982	[675]	[2105,849,900]	8	hSpCas9	negative selection	6037445
128252119	128252142	7	+	27260156	CAL120	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.07550288830638574	[1583]	[1889,2120,2188]	1	hSpCas9	negative selection	6101699
128254544	128254567	7	-	27260156	CAL120	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.09069953930034741	[425]	[349,745,564]	1	hSpCas9	negative selection	6101700
128254432	128254455	7	-	27260156	CAL120	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.43074194186191733	[300]	[499,413,597]	6	hSpCas9	negative selection	6101701
128254541	128254564	7	+	27260156	CADOES1	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.07695481222091138	[308]	[213,191,260,554]	1	hSpCas9	negative selection	6158694
128252033	128252056	7	-	27260156	CADOES1	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.2848595778593517	[97]	[64,114,134,129]	5	hSpCas9	negative selection	6158695
128254487	128254510	7	-	27260156	CADOES1	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.7848850088973319	[675]	[883,1197,1161,1089]	9	hSpCas9	negative selection	6158696
128252119	128252142	7	+	27260156	CADOES1	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.24193163704633225	[1583]	[1730,1671,1532,2043]	4	hSpCas9	negative selection	6222950
128254544	128254567	7	-	27260156	CADOES1	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.17809169992947085	[425]	[389,472,436,494]	3	hSpCas9	negative selection	6222951
128254432	128254455	7	-	27260156	CADOES1	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.5076157191094356	[300]	[372,351,314,557]	8	hSpCas9	negative selection	6222952
128254541	128254564	7	+	27260156	EWS502	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.1887239414317291	[308]	[340,274,233,290]	-3	hSpCas9	negative selection	6279945
128252033	128252056	7	-	27260156	EWS502	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.0482312015902675	[97]	[47,101,136,152]	0	hSpCas9	negative selection	6279946
128254487	128254510	7	-	27260156	EWS502	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.5246383624750407	[675]	[718,904,1071,1496]	8	hSpCas9	negative selection	6279947
128252119	128252142	7	+	27260156	EWS502	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-3.5772430062586125e-06	[1583]	[1337,1492,1981,1964]	0	hSpCas9	negative selection	6344201
128254544	128254567	7	-	27260156	EWS502	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.22152193228442552	[425]	[524,409,645,527]	4	hSpCas9	negative selection	6344202
128254432	128254455	7	-	27260156	EWS502	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.21796665238308843	[300]	[308,420,345,413]	4	hSpCas9	negative selection	6344203
128254541	128254564	7	+	27260156	EW8	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.18634209378021882	[308]	[313,299,286,240]	3	hSpCas9	negative selection	6401196
128252033	128252056	7	-	27260156	EW8	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.24333437171868422	[97]	[79,111,89,92]	4	hSpCas9	negative selection	6401197
128254487	128254510	7	-	27260156	EW8	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.33104269040520107	[675]	[871,660,538,727]	6	hSpCas9	negative selection	6401198
128252119	128252142	7	+	27260156	EW8	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.2602589494578049	[1583]	[1704,1398,1394,1687]	5	hSpCas9	negative selection	6465452
128254544	128254567	7	-	27260156	EW8	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.3018031855797396	[425]	[718,392,334,301]	5	hSpCas9	negative selection	6465453
128254432	128254455	7	-	27260156	EW8	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.04026641186460855	[300]	[295,203,252,253]	0	hSpCas9	negative selection	6465454
128254541	128254564	7	+	27260156	CORL105	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.3606023334370172	[308]	[334,189,310,298]	-6	hSpCas9	negative selection	6522447
128252033	128252056	7	-	27260156	CORL105	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.09057998919586696	[97]	[96,97,165,78]	-2	hSpCas9	negative selection	6522448
128254487	128254510	7	-	27260156	CORL105	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.46629618888724145	[675]	[1048,1095,1291,965]	8	hSpCas9	negative selection	6522449
128252119	128252142	7	+	27260156	CORL105	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.04322256934154889	[1583]	[1681,1553,2229,1799]	-1	hSpCas9	negative selection	6586703
128254544	128254567	7	-	27260156	CORL105	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.13085646579834115	[425]	[387,449,736,634]	2	hSpCas9	negative selection	6586704
128254432	128254455	7	-	27260156	CORL105	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.14996682508741904	[300]	[283,414,407,454]	3	hSpCas9	negative selection	6586705
128254541	128254564	7	+	27260156	HS294T	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.269860872017892	[308]	[63,53,68,236]	-4	hSpCas9	negative selection	6643698
128252033	128252056	7	-	27260156	HS294T	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.06681000144861171	[97]	[36,20,55,29]	-1	hSpCas9	negative selection	6643699
128254487	128254510	7	-	27260156	HS294T	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.4693018854275507	[675]	[447,390,299,284]	6	hSpCas9	negative selection	6643700
128252119	128252142	7	+	27260156	HS294T	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.09249722696606444	[1583]	[512,559,655,572]	-1	hSpCas9	negative selection	6707954
128254544	128254567	7	-	27260156	HS294T	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.04933143078380457	[425]	[180,119,149,242]	0	hSpCas9	negative selection	6707955
128254432	128254455	7	-	27260156	HS294T	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.06101713722343549	[300]	[96,54,100,259]	0	hSpCas9	negative selection	6707956
128254541	128254564	7	+	27260156	HCC44	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.5516304053972307	[308]	[243,281,223,194]	-7	hSpCas9	negative selection	6764949
128252033	128252056	7	-	27260156	HCC44	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.425804895174305	[97]	[217,132,181,77]	7	hSpCas9	negative selection	6764950
128254487	128254510	7	-	27260156	HCC44	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.4154391509362402	[675]	[935,1064,1226,868]	6	hSpCas9	negative selection	6764951
128252119	128252142	7	+	27260156	HCC44	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.11611336338966227	[1583]	[2028,1834,2423,1580]	1	hSpCas9	negative selection	6829205
128254544	128254567	7	-	27260156	HCC44	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	-0.1396633975763498	[425]	[573,264,674,313]	-2	hSpCas9	negative selection	6829206
128254432	128254455	7	-	27260156	HCC44	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.35719171461428795	[300]	[557,462,502,241]	6	hSpCas9	negative selection	6829207
128254541	128254564	7	+	27260156	G402	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.0019672829704323602	[308]	[350,319,355,469]	0	hSpCas9	negative selection	6886200
128252033	128252056	7	-	27260156	G402	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.8675015204278846	[97]	[83,277,64,418]	9	hSpCas9	negative selection	6886201
128254487	128254510	7	-	27260156	G402	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.5586503077851247	[675]	[850,1398,1472,1095]	7	hSpCas9	negative selection	6886202
128252119	128252142	7	+	27260156	G402	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.07605591182039029	[1583]	[2089,2247,1412,2392]	0	hSpCas9	negative selection	6950456
128254544	128254567	7	-	27260156	G402	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	1.0972331036459295	[425]	[882,1018,1188,1304]	9	hSpCas9	negative selection	6950457
128254432	128254455	7	-	27260156	G402	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.33940628838571224	[300]	[676,376,309,515]	4	hSpCas9	negative selection	6950458
128254541	128254564	7	+	27260156	L33	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.4208442292254837	[308]	[207,93,129,278]	-7	hSpCas9	negative selection	7007451
128252033	128252056	7	-	27260156	L33	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.08035922314143473	[97]	[100,46,62,54]	-2	hSpCas9	negative selection	7007452
128254487	128254510	7	-	27260156	L33	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.19147805461223832	[675]	[680,382,502,674]	4	hSpCas9	negative selection	7007453
128252119	128252142	7	+	27260156	L33	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.22056625323152868	[1583]	[1220,611,847,1376]	-5	hSpCas9	negative selection	7071707
128254544	128254567	7	-	27260156	L33	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.031525364995603336	[425]	[403,145,347,428]	0	hSpCas9	negative selection	7071708
128254432	128254455	7	-	27260156	L33	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.13859318074231897	[300]	[302,112,215,402]	3	hSpCas9	negative selection	7071709
128254541	128254564	7	+	27260156	K562	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.18394972102936163	[308]	[291,390,353,220]	2	hSpCas9	negative selection	7128702
128252033	128252056	7	-	27260156	K562	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.05723980472400925	[97]	[58,28,231,16]	0	hSpCas9	negative selection	7128703
128254487	128254510	7	-	27260156	K562	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.6224061187998712	[675]	[827,1101,765,987]	7	hSpCas9	negative selection	7128704
128252119	128252142	7	+	27260156	K562	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.43634447124315234	[1583]	[2334,1857,1825,1644]	5	hSpCas9	negative selection	7192958
128254544	128254567	7	-	27260156	K562	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.1854427030340674	[425]	[252,337,578,517]	2	hSpCas9	negative selection	7192959
128254432	128254455	7	-	27260156	K562	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.3853992439349225	[300]	[269,639,247,255]	5	hSpCas9	negative selection	7192960
128254541	128254564	7	+	27260156	HT29	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.25441548384533386	[308]	[269,255,364,352]	-5	hSpCas9	negative selection	7249953
128252033	128252056	7	-	27260156	HT29	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.40712357133549526	[97]	[142,131,253,104]	7	hSpCas9	negative selection	7249954
128254487	128254510	7	-	27260156	HT29	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.36030400863336765	[675]	[1300,1126,1005,830]	7	hSpCas9	negative selection	7249955
128252119	128252142	7	+	27260156	HT29	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.06740533979434038	[1583]	[2370,1995,2260,1515]	1	hSpCas9	negative selection	7314209
128254544	128254567	7	-	27260156	HT29	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.09526101772476545	[425]	[629,702,578,341]	1	hSpCas9	negative selection	7314210
128254432	128254455	7	-	27260156	HT29	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.04939749923992809	[300]	[377,411,376,262]	-1	hSpCas9	negative selection	7314211
128254541	128254564	7	+	27260156	MHHES1	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.6354686433521466	[308]	[339,201,251,130]	-8	hSpCas9	negative selection	7371204
128252033	128252056	7	-	27260156	MHHES1	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.10409522776414315	[97]	[66,129,75,178]	2	hSpCas9	negative selection	7371205
128254487	128254510	7	-	27260156	MHHES1	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.503659148637906	[675]	[986,1481,1215,722]	8	hSpCas9	negative selection	7371206
128252119	128252142	7	+	27260156	MHHES1	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.04886061353245119	[1583]	[1906,1930,2061,1141]	-1	hSpCas9	negative selection	7435460
128254544	128254567	7	-	27260156	MHHES1	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.2912681841528479	[425]	[1028,510,603,303]	5	hSpCas9	negative selection	7435461
128254432	128254455	7	-	27260156	MHHES1	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.1369550180439688	[300]	[350,324,480,328]	2	hSpCas9	negative selection	7435462
128254541	128254564	7	+	27260156	MEWO	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.06278638885271781	[308]	[368,253,295]	1	hSpCas9	negative selection	7492455
128252033	128252056	7	-	27260156	MEWO	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.11900598421585107	[97]	[141,79,84]	2	hSpCas9	negative selection	7492456
128254487	128254510	7	-	27260156	MEWO	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.16118373948342024	[675]	[763,796,570]	3	hSpCas9	negative selection	7492457
128252119	128252142	7	+	27260156	MEWO	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.07034067784683473	[1583]	[1796,1332,1178]	-1	hSpCas9	negative selection	7556711
128254544	128254567	7	-	27260156	MEWO	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	-0.018849727452304038	[425]	[412,360,409]	0	hSpCas9	negative selection	7556712
128254432	128254455	7	-	27260156	MEWO	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.05412165187322082	[300]	[373,262,255]	1	hSpCas9	negative selection	7556713
128254541	128254564	7	+	27260156	LNCAPCLONEFGC	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.33050681199282606	[308]	[345,211,164,156]	-5	hSpCas9	negative selection	7613706
128252033	128252056	7	-	27260156	LNCAPCLONEFGC	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.4010960173806657	[97]	[106,128,155,81]	6	hSpCas9	negative selection	7613707
128254487	128254510	7	-	27260156	LNCAPCLONEFGC	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.2560824529495842	[675]	[595,895,842,597]	4	hSpCas9	negative selection	7613708
128252119	128252142	7	+	27260156	LNCAPCLONEFGC	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.09691648607444092	[1583]	[1582,1117,1804,1697]	1	hSpCas9	negative selection	7677962
128254544	128254567	7	-	27260156	LNCAPCLONEFGC	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.08217754519871288	[425]	[366,390,416,461]	1	hSpCas9	negative selection	7677963
128254432	128254455	7	-	27260156	LNCAPCLONEFGC	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.4184528138454753	[300]	[347,339,314,448]	6	hSpCas9	negative selection	7677964
128254541	128254564	7	+	27260156	PANC0327	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.4241610962713207	[308]	[201,178,86,352]	-6	hSpCas9	negative selection	7734957
128252033	128252056	7	-	27260156	PANC0327	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.5887642844541627	[97]	[101,203,174,30]	8	hSpCas9	negative selection	7734958
128254487	128254510	7	-	27260156	PANC0327	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.8576610654055888	[675]	[1014,881,1206,1268]	9	hSpCas9	negative selection	7734959
128252119	128252142	7	+	27260156	PANC0327	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.12992290171486087	[1583]	[1567,1315,1840,1464]	2	hSpCas9	negative selection	7799213
128254544	128254567	7	-	27260156	PANC0327	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.16394447972656323	[425]	[435,342,381,545]	2	hSpCas9	negative selection	7799214
128254432	128254455	7	-	27260156	PANC0327	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.12701076544924128	[300]	[130,236,278,323]	-2	hSpCas9	negative selection	7799215
128254541	128254564	7	+	27260156	NCIH2009	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.5462279350296044	[308]	[384,245,273]	-6	hSpCas9	negative selection	7856208
128252033	128252056	7	-	27260156	NCIH2009	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.26914985359648513	[97]	[168,36,146]	-4	hSpCas9	negative selection	7856209
128254487	128254510	7	-	27260156	NCIH2009	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.2858121679092679	[675]	[1152,1293,1002]	4	hSpCas9	negative selection	7856210
128252119	128252142	7	+	27260156	NCIH2009	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.044497562778422095	[1583]	[2882,1577,2128]	0	hSpCas9	negative selection	7920464
128254544	128254567	7	-	27260156	NCIH2009	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.22562133352916017	[425]	[764,546,790]	3	hSpCas9	negative selection	7920465
128254432	128254455	7	-	27260156	NCIH2009	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.5878213481304666	[300]	[286,189,364]	-6	hSpCas9	negative selection	7920466
128254541	128254564	7	+	27260156	NCIH1373	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.6907607291051272	[308]	[158,321,234,29]	-6	hSpCas9	negative selection	7977459
128252033	128252056	7	-	27260156	NCIH1373	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.50684660008594	[97]	[106,224,148,32]	5	hSpCas9	negative selection	7977460
128254487	128254510	7	-	27260156	NCIH1373	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.793516438301857	[675]	[2519,675,1085,320]	7	hSpCas9	negative selection	7977461
128252119	128252142	7	+	27260156	NCIH1373	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.5393818179618879	[1583]	[3586,1668,2752,669]	5	hSpCas9	negative selection	8041715
128254544	128254567	7	-	27260156	NCIH1373	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	1.2100752158880568	[425]	[1702,513,1204,301]	9	hSpCas9	negative selection	8041716
128254432	128254455	7	-	27260156	NCIH1373	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.17107288642933594	[300]	[249,233,321,103]	-2	hSpCas9	negative selection	8041717
128254541	128254564	7	+	27260156	PATU8902	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.8292923650022108	[308]	[160,334,268,189]	-6	hSpCas9	negative selection	8098710
128252033	128252056	7	-	27260156	PATU8902	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.7013800987532977	[97]	[190,111,339,210]	7	hSpCas9	negative selection	8098711
128254487	128254510	7	-	27260156	PATU8902	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	1.0416460035483293	[675]	[1827,2218,1297,2644]	9	hSpCas9	negative selection	8098712
128252119	128252142	7	+	27260156	PATU8902	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.14208882852156712	[1583]	[2370,3100,1653,2846]	1	hSpCas9	negative selection	8162966
128254544	128254567	7	-	27260156	PATU8902	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.5418794985399665	[425]	[761,1539,589,598]	5	hSpCas9	negative selection	8162967
128254432	128254455	7	-	27260156	PATU8902	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.3086660456124901	[300]	[441,814,341,521]	3	hSpCas9	negative selection	8162968
128254541	128254564	7	+	27260156	PANC1	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.015203549670443683	[308]	[283,248,361,183]	0	hSpCas9	negative selection	8219961
128252033	128252056	7	-	27260156	PANC1	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.42808003731314725	[97]	[59,58,196,123]	7	hSpCas9	negative selection	8219962
128254487	128254510	7	-	27260156	PANC1	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.45312728543079883	[675]	[522,1149,823,754]	7	hSpCas9	negative selection	8219963
128252119	128252142	7	+	27260156	PANC1	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.2949071871949831	[1583]	[1790,2195,1522,1303]	5	hSpCas9	negative selection	8284217
128254544	128254567	7	-	27260156	PANC1	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.32124536305421636	[425]	[525,653,452,259]	5	hSpCas9	negative selection	8284218
128254432	128254455	7	-	27260156	PANC1	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.10690433512227815	[300]	[288,259,310,249]	1	hSpCas9	negative selection	8284219
128254541	128254564	7	+	27260156	PANC0813	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.1106877504787161	[308]	[554,427,323,280]	1	hSpCas9	negative selection	8341212
128252033	128252056	7	-	27260156	PANC0813	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.11783232024243118	[97]	[137,57,120,109]	-2	hSpCas9	negative selection	8341213
128254487	128254510	7	-	27260156	PANC0813	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.19545505778397188	[675]	[985,731,1062,864]	3	hSpCas9	negative selection	8341214
128252119	128252142	7	+	27260156	PANC0813	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.12259451225591045	[1583]	[2105,2016,1745,2224]	2	hSpCas9	negative selection	8405468
128254544	128254567	7	-	27260156	PANC0813	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.4080949441121041	[425]	[800,634,599,632]	6	hSpCas9	negative selection	8405469
128254432	128254455	7	-	27260156	PANC0813	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.5482290970191775	[300]	[433,441,438,731]	8	hSpCas9	negative selection	8405470
128254541	128254564	7	+	27260156	RDES	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.4661602266535312	[308]	[245,224,273,285]	-7	hSpCas9	negative selection	8462463
128252033	128252056	7	-	27260156	RDES	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.44615420655370785	[97]	[148,189,93,173]	7	hSpCas9	negative selection	8462464
128254487	128254510	7	-	27260156	RDES	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.5555547646482261	[675]	[960,966,1423,1269]	8	hSpCas9	negative selection	8462465
128252119	128252142	7	+	27260156	RDES	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.09768593470194853	[1583]	[1381,2045,1975,2541]	1	hSpCas9	negative selection	8526719
128254544	128254567	7	-	27260156	RDES	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.08368443184886892	[425]	[419,518,490,674]	1	hSpCas9	negative selection	8526720
128254432	128254455	7	-	27260156	RDES	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.250073558613756	[300]	[241,299,321,303]	-4	hSpCas9	negative selection	8526721
128254541	128254564	7	+	27260156	PC3	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.552704592957646	[308]	[81,263,380,218]	-8	hSpCas9	negative selection	8583714
128252033	128252056	7	-	27260156	PC3	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.21094841363154604	[97]	[54,94,83,107]	-5	hSpCas9	negative selection	8583715
128254487	128254510	7	-	27260156	PC3	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.21456206569350378	[675]	[481,824,1023,950]	5	hSpCas9	negative selection	8583716
128252119	128252142	7	+	27260156	PC3	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.2291291589099118	[1583]	[716,1210,2439,1629]	-5	hSpCas9	negative selection	8647970
128254544	128254567	7	-	27260156	PC3	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	-0.0475366771542286	[425]	[135,597,674,422]	-1	hSpCas9	negative selection	8647971
128254432	128254455	7	-	27260156	PC3	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.08221782666169009	[300]	[199,199,558,438]	1	hSpCas9	negative selection	8647972
128254541	128254564	7	+	27260156	PATU8988T	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.07764656937708414	[308]	[368,245,457,166]	1	hSpCas9	negative selection	8704965
128252033	128252056	7	-	27260156	PATU8988T	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.037101286112561915	[97]	[65,133,56,138]	0	hSpCas9	negative selection	8704966
128254487	128254510	7	-	27260156	PATU8988T	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.47469201315064613	[675]	[1006,983,674,980]	7	hSpCas9	negative selection	8704967
128252119	128252142	7	+	27260156	PATU8988T	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.32037964424447396	[1583]	[1218,1071,1326,1272]	-5	hSpCas9	negative selection	8769221
128254544	128254567	7	-	27260156	PATU8988T	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.2261439148683153	[425]	[345,624,420,553]	4	hSpCas9	negative selection	8769222
128254432	128254455	7	-	27260156	PATU8988T	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.3378806257399698	[300]	[138,246,255,283]	-5	hSpCas9	negative selection	8769223
128254541	128254564	7	+	27260156	T47D	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.21648254270372036	[308]	[302,278,373,283]	-5	hSpCas9	negative selection	8826216
128252033	128252056	7	-	27260156	T47D	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.1341973581278455	[97]	[182,79,146,93]	3	hSpCas9	negative selection	8826217
128254487	128254510	7	-	27260156	T47D	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.4192028158769202	[675]	[1000,1110,1058,1034]	8	hSpCas9	negative selection	8826218
128252119	128252142	7	+	27260156	T47D	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.07859803697854018	[1583]	[2016,1880,1954,1946]	1	hSpCas9	negative selection	8890472
128254544	128254567	7	-	27260156	T47D	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.08519554386899743	[425]	[472,493,449,697]	1	hSpCas9	negative selection	8890473
128254432	128254455	7	-	27260156	T47D	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.15479889725711332	[300]	[409,323,389,444]	3	hSpCas9	negative selection	8890474
128254541	128254564	7	+	27260156	SU8686	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.3465068288290245	[308]	[226,191,211,356]	-5	hSpCas9	negative selection	8947467
128252033	128252056	7	-	27260156	SU8686	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.11938050932080291	[97]	[104,95,134,83]	2	hSpCas9	negative selection	8947468
128254487	128254510	7	-	27260156	SU8686	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.328877410163106	[675]	[625,879,758,1165]	5	hSpCas9	negative selection	8947469
128252119	128252142	7	+	27260156	SU8686	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.13759826479064485	[1583]	[1471,1581,1797,2166]	2	hSpCas9	negative selection	9011723
128254544	128254567	7	-	27260156	SU8686	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.14411156322174745	[425]	[398,409,428,672]	2	hSpCas9	negative selection	9011724
128254432	128254455	7	-	27260156	SU8686	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.1966788793644325	[300]	[315,322,305,440]	3	hSpCas9	negative selection	9011725
128254541	128254564	7	+	27260156	SKES1	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.6017325766851165	[308]	[174,305,169,171]	-8	hSpCas9	negative selection	9068718
128252033	128252056	7	-	27260156	SKES1	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.4812644412460567	[97]	[144,101,207,90]	8	hSpCas9	negative selection	9068719
128254487	128254510	7	-	27260156	SKES1	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.3929357745698636	[675]	[1044,897,936,697]	7	hSpCas9	negative selection	9068720
128252119	128252142	7	+	27260156	SKES1	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.09533008876163596	[1583]	[1578,1587,1345,1422]	-2	hSpCas9	negative selection	9132974
128254544	128254567	7	-	27260156	SKES1	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	-0.05471672703778424	[425]	[419,534,322,375]	-1	hSpCas9	negative selection	9132975
128254432	128254455	7	-	27260156	SKES1	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	-0.2490056736857308	[300]	[217,249,318,218]	-5	hSpCas9	negative selection	9132976
128254541	128254564	7	+	27260156	TOV112D	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.09964949571220771	[308]	[166,412,156,433]	-2	hSpCas9	negative selection	9189969
128252033	128252056	7	-	27260156	TOV112D	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.34968257734622377	[97]	[84,120,91,22]	-6	hSpCas9	negative selection	9189970
128254487	128254510	7	-	27260156	TOV112D	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.2228378862965541	[675]	[580,882,530,1158]	4	hSpCas9	negative selection	9189971
128252119	128252142	7	+	27260156	TOV112D	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.07510205712403728	[1583]	[1131,1627,1573,1680]	-1	hSpCas9	negative selection	9254225
128254544	128254567	7	-	27260156	TOV112D	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.08776016258670775	[425]	[460,485,544,332]	1	hSpCas9	negative selection	9254226
128254432	128254455	7	-	27260156	TOV112D	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.4818261153711435	[300]	[700,409,201,391]	8	hSpCas9	negative selection	9254227
128254541	128254564	7	+	27260156	TC71	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.24550442589839871	[308]	[284,249,338,238]	-6	hSpCas9	negative selection	9311220
128252033	128252056	7	-	27260156	TC71	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.025960803072242022	[97]	[107,90,73,142]	0	hSpCas9	negative selection	9311221
128254487	128254510	7	-	27260156	TC71	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.2483878111978387	[675]	[705,921,888,932]	6	hSpCas9	negative selection	9311222
128252119	128252142	7	+	27260156	TC71	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	-0.043533598021512354	[1583]	[1418,1717,1851,1595]	-1	hSpCas9	negative selection	9375476
128254544	128254567	7	-	27260156	TC71	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	-0.011420559707250894	[425]	[362,581,350,525]	0	hSpCas9	negative selection	9375477
128254432	128254455	7	-	27260156	TC71	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.1938570030495712	[300]	[340,350,357,430]	5	hSpCas9	negative selection	9375478
128254541	128254564	7	+	27260156	TC32	viability	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.1722935164450068	[308]	[220,228,248,333]	-3	hSpCas9	negative selection	9432471
128252033	128252056	7	-	27260156	TC32	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.07806652517701451	[97]	[48,36,212,91]	-1	hSpCas9	negative selection	9432472
128254487	128254510	7	-	27260156	TC32	viability	GTTGGTAGACTGCCAGTGTCTGG	LEP	ENSG00000174697	0.6949421599440687	[675]	[964,671,1424,1214]	9	hSpCas9	negative selection	9432473
128252119	128252142	7	+	27260156	TC32	viability	TCATCAAGACAATTGTCACCAGG	LEP	ENSG00000174697	0.05246171213256079	[1583]	[1521,1084,1934,1799]	1	hSpCas9	negative selection	9496727
128254544	128254567	7	-	27260156	TC32	viability	TCTCCAGGTCGTTGGATATTTGG	LEP	ENSG00000174697	0.37607748336409774	[425]	[567,487,571,424]	6	hSpCas9	negative selection	9496728
128254432	128254455	7	-	27260156	TC32	viability	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.0487362647741314	[300]	[176,187,502,382]	0	hSpCas9	negative selection	9496729
128252033	128252056	7	-	27869803	HPAFII	viability after 27 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.561930982059023	[267]	[111,287,NaN]	4	hSpCas9	negative selection	9597911
128254432	128254455	7	-	27869803	HPAFII	viability after 27 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.5720970085493098	[690]	[532,545,NaN]	4	hSpCas9	negative selection	9597912
128254541	128254564	7	+	27869803	HPAFII	viability after 27 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-1.0276199356532945	[146]	[74,6,NaN]	-6	hSpCas9	negative selection	9597913
128254568	128254591	7	-	27869803	HPAFII	viability after 27 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-1.1944100700029066	[147]	[39,28,NaN]	-7	hSpCas9	negative selection	9597914
128254670	128254693	7	+	27869803	HPAFII	viability after 27 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.562754976688224	[636]	[205,243,NaN]	-4	hSpCas9	negative selection	9597915
128252033	128252056	7	-	27869803	HPAFII	viability after 15 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.44828795048232506	[267]	[199,217,NaN]	-5	hSpCas9	negative selection	9680360
128254432	128254455	7	-	27869803	HPAFII	viability after 15 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.46989415410925073	[690]	[1482,745,NaN]	5	hSpCas9	negative selection	9680361
128254541	128254564	7	+	27869803	HPAFII	viability after 15 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.7210757320655569	[146]	[175,45,NaN]	-6	hSpCas9	negative selection	9680362
128254568	128254591	7	-	27869803	HPAFII	viability after 15 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.11966287029605494	[147]	[138,150,NaN]	-1	hSpCas9	negative selection	9680363
128254670	128254693	7	+	27869803	HPAFII	viability after 15 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.37516426899148836	[636]	[607,477,NaN]	-4	hSpCas9	negative selection	9680364
128252033	128252056	7	-	27869803	ASPC1	viability after 36 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.1954766470470421	[627]	[74,440,72]	-2	hSpCas9	negative selection	9762809
128254432	128254455	7	-	27869803	ASPC1	viability after 36 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.37905023612040534	[1680]	[427,911,871]	4	hSpCas9	negative selection	9762810
128254541	128254564	7	+	27869803	ASPC1	viability after 36 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	0.34567219129699533	[348]	[131,246,95]	3	hSpCas9	negative selection	9762811
128254568	128254591	7	-	27869803	ASPC1	viability after 36 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-1.2663792845636328	[433]	[94,24,69]	-8	hSpCas9	negative selection	9762812
128254670	128254693	7	+	27869803	ASPC1	viability after 36 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.04398565308094993	[1379]	[405,381,572]	0	hSpCas9	negative selection	9762813
128252033	128252056	7	-	27869803	PATU8988S	viability after 35 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.36628817983883266	[657]	[387,294,NaN]	4	hSpCas9	negative selection	9845258
128254432	128254455	7	-	27869803	PATU8988S	viability after 35 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.054817871923869	[1395]	[589,577,NaN]	0	hSpCas9	negative selection	9845259
128254541	128254564	7	+	27869803	PATU8988S	viability after 35 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.5928742174002484	[259]	[37,100,NaN]	-6	hSpCas9	negative selection	9845260
128254568	128254591	7	-	27869803	PATU8988S	viability after 35 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.41005019536579945	[354]	[179,199,NaN]	4	hSpCas9	negative selection	9845261
128254670	128254693	7	+	27869803	PATU8988S	viability after 35 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	0.4710568320402839	[1285]	[684,750,NaN]	5	hSpCas9	negative selection	9845262
128252033	128252056	7	-	27869803	PATU8988S	viability after 31 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.23057688974317292	[657]	[324,285,NaN]	3	hSpCas9	negative selection	9927707
128254432	128254455	7	-	27869803	PATU8988S	viability after 31 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.166101490985747	[1395]	[668,567,NaN]	2	hSpCas9	negative selection	9927708
128254541	128254564	7	+	27869803	PATU8988S	viability after 31 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.2905951143926677	[259]	[82,86,NaN]	-3	hSpCas9	negative selection	9927709
128254568	128254591	7	-	27869803	PATU8988S	viability after 31 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.44422869287478794	[354]	[174,214,NaN]	5	hSpCas9	negative selection	9927710
128254670	128254693	7	+	27869803	PATU8988S	viability after 31 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	0.24925588879446003	[1285]	[473,781,NaN]	3	hSpCas9	negative selection	9927711
128252033	128252056	7	-	27869803	HPAFII	viability after 35 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.5316399026243858	[267]	[94,309,NaN]	3	hSpCas9	negative selection	10010156
128254432	128254455	7	-	27869803	HPAFII	viability after 35 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.6613833458647165	[690]	[501,610,NaN]	4	hSpCas9	negative selection	10010157
128254541	128254564	7	+	27869803	HPAFII	viability after 35 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.3976571679487292	[146]	[95,11,NaN]	-2	hSpCas9	negative selection	10010158
128254568	128254591	7	-	27869803	HPAFII	viability after 35 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.2621736944959797	[147]	[69,53,NaN]	-2	hSpCas9	negative selection	10010159
128254670	128254693	7	+	27869803	HPAFII	viability after 35 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-1.3061385119717372	[636]	[128,131,NaN]	-6	hSpCas9	negative selection	10010160
128252033	128252056	7	-	27869803	HPAFII	viability after 31 days	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.22981349474244972	[267]	[61,300,NaN]	1	hSpCas9	negative selection	10092605
128254432	128254455	7	-	27869803	HPAFII	viability after 31 days	CCCAGGAATGAAGTCCAAACCGG	LEP	ENSG00000174697	0.6184408611031744	[690]	[647,537,NaN]	4	hSpCas9	negative selection	10092606
128254541	128254564	7	+	27869803	HPAFII	viability after 31 days	GATCCAAATATCCAACGACCTGG	LEP	ENSG00000174697	-0.5596824798384862	[146]	[99,7,NaN]	-4	hSpCas9	negative selection	10092607
128254568	128254591	7	-	27869803	HPAFII	viability after 31 days	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-1.2007286590913875	[147]	[27,44,NaN]	-6	hSpCas9	negative selection	10092608
128254670	128254693	7	+	27869803	HPAFII	viability after 31 days	TTCAGGCTACTCCACAGAGGTGG	LEP	ENSG00000174697	-0.46028277170396137	[636]	[233,287,NaN]	-3	hSpCas9	negative selection	10092609
128252033	128252056	7	-	28162770	P31FUJ	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.36153551853658117	[81]	[74]	-3	hSpCas9	negative selection	10183905
128254734	128254757	7	+	28162770	P31FUJ	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-0.3157915690854102	[160]	[151]	-3	hSpCas9	negative selection	10183906
128252116	128252139	7	-	28162770	P31FUJ	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.6707680329025284	[231]	[433]	7	hSpCas9	negative selection	10183907
128252137	128252160	7	-	28162770	P31FUJ	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	-0.0282634478907291	[603]	[695]	0	hSpCas9	negative selection	10183908
128252005	128252028	7	+	28162770	P31FUJ	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	0.5903200335015419	[363]	[643]	6	hSpCas9	negative selection	10183909
128252019	128252042	7	+	28162770	P31FUJ	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.6842841583000285	[563]	[1064]	7	hSpCas9	negative selection	10183910
128254568	128254591	7	-	28162770	P31FUJ	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.2959960309015727	[209]	[200]	-3	hSpCas9	negative selection	10183911
128254714	128254737	7	+	28162770	P31FUJ	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	-0.6096054852057471	[421]	[324]	-5	hSpCas9	negative selection	10183912
128254457	128254480	7	-	28162770	P31FUJ	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	0.1186701660869991	[347]	[443]	1	hSpCas9	negative selection	10183913
128254667	128254690	7	+	28162770	P31FUJ	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	-0.23600463645272252	[450]	[449]	-2	hSpCas9	negative selection	10183914
128252033	128252056	7	-	28162770	TF1	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10353271
128254734	128254757	7	+	28162770	TF1	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10353272
128252116	128252139	7	-	28162770	TF1	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	NaN	[NaN]	[180]	1	hSpCas9	negative selection	10353273
128252137	128252160	7	-	28162770	TF1	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	NaN	[NaN]	[468]	1	hSpCas9	negative selection	10353274
128252005	128252028	7	+	28162770	TF1	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	NaN	[NaN]	[515]	1	hSpCas9	negative selection	10353275
128252019	128252042	7	+	28162770	TF1	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	NaN	[NaN]	[660]	1	hSpCas9	negative selection	10353276
128254568	128254591	7	-	28162770	TF1	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10353277
128254714	128254737	7	+	28162770	TF1	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	NaN	[NaN]	[268]	1	hSpCas9	negative selection	10353278
128254457	128254480	7	-	28162770	TF1	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	NaN	[NaN]	[192]	1	hSpCas9	negative selection	10353279
128254667	128254690	7	+	28162770	TF1	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	NaN	[NaN]	[349]	1	hSpCas9	negative selection	10353280
128252033	128252056	7	-	28162770	SKM1	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.5650214250872418	[12]	[33]	5	hSpCas9	negative selection	10522637
128254734	128254757	7	+	28162770	SKM1	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-0.33657487085176363	[34]	[48]	-3	hSpCas9	negative selection	10522638
128252116	128252139	7	-	28162770	SKM1	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.4957385999019234	[68]	[171]	5	hSpCas9	negative selection	10522639
128252137	128252160	7	-	28162770	SKM1	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.027621696913662896	[196]	[354]	0	hSpCas9	negative selection	10522640
128252005	128252028	7	+	28162770	SKM1	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	0.7015602580350073	[111]	[321]	6	hSpCas9	negative selection	10522641
128252019	128252042	7	+	28162770	SKM1	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.7629608026991508	[177]	[533]	7	hSpCas9	negative selection	10522642
128254568	128254591	7	-	28162770	SKM1	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-1.1724989451061387	[50]	[39]	-7	hSpCas9	negative selection	10522643
128254714	128254737	7	+	28162770	SKM1	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	0.7580453122850342	[97]	[292]	7	hSpCas9	negative selection	10522644
128254457	128254480	7	-	28162770	SKM1	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	-0.30415339315938633	[87]	[125]	-3	hSpCas9	negative selection	10522645
128254667	128254690	7	+	28162770	SKM1	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	-0.3598959450863829	[97]	[134]	-3	hSpCas9	negative selection	10522646
128252033	128252056	7	-	28162770	SKM1	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.5650214250872418	[12]	[33]	5	hSpCas9	negative selection	10692003
128254734	128254757	7	+	28162770	SKM1	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-0.33657487085176363	[34]	[48]	-3	hSpCas9	negative selection	10692004
128252116	128252139	7	-	28162770	SKM1	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.4957385999019234	[68]	[171]	5	hSpCas9	negative selection	10692005
128252137	128252160	7	-	28162770	SKM1	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.027621696913662896	[196]	[354]	0	hSpCas9	negative selection	10692006
128252005	128252028	7	+	28162770	SKM1	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	0.7015602580350073	[111]	[321]	6	hSpCas9	negative selection	10692007
128252019	128252042	7	+	28162770	SKM1	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.7629608026991508	[177]	[533]	7	hSpCas9	negative selection	10692008
128254568	128254591	7	-	28162770	SKM1	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-1.1724989451061387	[50]	[39]	-7	hSpCas9	negative selection	10692009
128254714	128254737	7	+	28162770	SKM1	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	0.7580453122850342	[97]	[292]	7	hSpCas9	negative selection	10692010
128254457	128254480	7	-	28162770	SKM1	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	-0.30415339315938633	[87]	[125]	-3	hSpCas9	negative selection	10692011
128254667	128254690	7	+	28162770	SKM1	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	-0.3598959450863829	[97]	[134]	-3	hSpCas9	negative selection	10692012
128252033	128252056	7	-	28162770	PL21	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-3.8873232267610196	[101]	[2]	-9	hSpCas9	negative selection	10861369
128254734	128254757	7	+	28162770	PL21	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	1.102842413134405	[91]	[85]	8	hSpCas9	negative selection	10861370
128252116	128252139	7	-	28162770	PL21	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.5480629179096269	[230]	[146]	5	hSpCas9	negative selection	10861371
128252137	128252160	7	-	28162770	PL21	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.10570481263127118	[725]	[339]	0	hSpCas9	negative selection	10861372
128252005	128252028	7	+	28162770	PL21	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	0.7352328657858718	[362]	[262]	6	hSpCas9	negative selection	10861373
128252019	128252042	7	+	28162770	PL21	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.3921732514219747	[589]	[336]	3	hSpCas9	negative selection	10861374
128254568	128254591	7	-	28162770	PL21	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-1.6161484323382915	[161]	[22]	-8	hSpCas9	negative selection	10861375
128254714	128254737	7	+	28162770	PL21	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	1.04999926506146	[343]	[309]	8	hSpCas9	negative selection	10861376
128254457	128254480	7	-	28162770	PL21	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	-0.7676799797615301	[265]	[67]	-5	hSpCas9	negative selection	10861377
128254667	128254690	7	+	28162770	PL21	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	-1.1097156480974673	[356]	[71]	-6	hSpCas9	negative selection	10861378
128252033	128252056	7	-	28162770	P31FUJ	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.36153551853658117	[81]	[74]	-3	hSpCas9	negative selection	11030735
128254734	128254757	7	+	28162770	P31FUJ	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-0.3157915690854102	[160]	[151]	-3	hSpCas9	negative selection	11030736
128252116	128252139	7	-	28162770	P31FUJ	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.6707680329025284	[231]	[433]	7	hSpCas9	negative selection	11030737
128252137	128252160	7	-	28162770	P31FUJ	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	-0.0282634478907291	[603]	[695]	0	hSpCas9	negative selection	11030738
128252005	128252028	7	+	28162770	P31FUJ	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	0.5903200335015419	[363]	[643]	6	hSpCas9	negative selection	11030739
128252019	128252042	7	+	28162770	P31FUJ	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.6842841583000285	[563]	[1064]	7	hSpCas9	negative selection	11030740
128254568	128254591	7	-	28162770	P31FUJ	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.2959960309015727	[209]	[200]	-3	hSpCas9	negative selection	11030741
128254714	128254737	7	+	28162770	P31FUJ	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	-0.6096054852057471	[421]	[324]	-5	hSpCas9	negative selection	11030742
128254457	128254480	7	-	28162770	P31FUJ	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	0.1186701660869991	[347]	[443]	1	hSpCas9	negative selection	11030743
128254667	128254690	7	+	28162770	P31FUJ	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	-0.23600463645272252	[450]	[449]	-2	hSpCas9	negative selection	11030744
128252033	128252056	7	-	28162770	OCIAML5	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.40666769753617127	[55]	[133]	3	hSpCas9	negative selection	11200101
128254734	128254757	7	+	28162770	OCIAML5	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-0.4521359639753617	[71]	[94]	-3	hSpCas9	negative selection	11200102
128252116	128252139	7	-	28162770	OCIAML5	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-0.18464190995086793	[186]	[296]	-1	hSpCas9	negative selection	11200103
128252137	128252160	7	-	28162770	OCIAML5	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.5991445409683318	[383]	[1049]	5	hSpCas9	negative selection	11200104
128252005	128252028	7	+	28162770	OCIAML5	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	1.832220667660803	[151]	[976]	9	hSpCas9	negative selection	11200105
128252019	128252042	7	+	28162770	OCIAML5	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.7477538885842727	[321]	[975]	6	hSpCas9	negative selection	11200106
128254568	128254591	7	-	28162770	OCIAML5	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.6124006376705986	[103]	[286]	5	hSpCas9	negative selection	11200107
128254714	128254737	7	+	28162770	OCIAML5	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	0.25113231677750214	[235]	[506]	2	hSpCas9	negative selection	11200108
128254457	128254480	7	-	28162770	OCIAML5	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	0.6364795981504235	[164]	[462]	5	hSpCas9	negative selection	11200109
128254667	128254690	7	+	28162770	OCIAML5	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	0.6556529309246988	[210]	[599]	6	hSpCas9	negative selection	11200110
128252033	128252056	7	-	28162770	EOL1	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.5296281216152676	[136]	[49]	-4	hSpCas9	negative selection	11369467
128254734	128254757	7	+	28162770	EOL1	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	0.9882733691809218	[154]	[161]	8	hSpCas9	negative selection	11369468
128252116	128252139	7	-	28162770	EOL1	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.6078123459034945	[415]	[333]	5	hSpCas9	negative selection	11369469
128252137	128252160	7	-	28162770	EOL1	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.41386469680793425	[1163]	[816]	4	hSpCas9	negative selection	11369470
128252005	128252028	7	+	28162770	EOL1	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	0.42057654387140264	[735]	[518]	4	hSpCas9	negative selection	11369471
128252019	128252042	7	+	28162770	EOL1	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.4834210434230297	[1115]	[821]	4	hSpCas9	negative selection	11369472
128254568	128254591	7	-	28162770	EOL1	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.3271481676111556	[232]	[153]	3	hSpCas9	negative selection	11369473
128254714	128254737	7	+	28162770	EOL1	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	0.056107475803812035	[397]	[217]	0	hSpCas9	negative selection	11369474
128254457	128254480	7	-	28162770	EOL1	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	0.21405438876551944	[305]	[186]	2	hSpCas9	negative selection	11369475
128254667	128254690	7	+	28162770	EOL1	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	0.3303667408199996	[470]	[311]	3	hSpCas9	negative selection	11369476
128252033	128252056	7	-	28162770	MOLM13	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.5739310189549033	[117]	[126]	4	hSpCas9	negative selection	11538833
128254734	128254757	7	+	28162770	MOLM13	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-0.624556867220016	[144]	[67]	-4	hSpCas9	negative selection	11538834
128252116	128252139	7	-	28162770	MOLM13	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	1.4525414172111428	[377]	[747]	9	hSpCas9	negative selection	11538835
128252137	128252160	7	-	28162770	MOLM13	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.8961829775256895	[974]	[1311]	6	hSpCas9	negative selection	11538836
128252005	128252028	7	+	28162770	MOLM13	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	1.033156080924815	[589]	[872]	7	hSpCas9	negative selection	11538837
128252019	128252042	7	+	28162770	MOLM13	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.8006474096326928	[928]	[1169]	6	hSpCas9	negative selection	11538838
128254568	128254591	7	-	28162770	MOLM13	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.34838228708848973	[238]	[219]	2	hSpCas9	negative selection	11538839
128254714	128254737	7	+	28162770	MOLM13	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	-0.6496226670178902	[472]	[217]	-4	hSpCas9	negative selection	11538840
128254457	128254480	7	-	28162770	MOLM13	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	0.3516363130487308	[309]	[285]	2	hSpCas9	negative selection	11538841
128254667	128254690	7	+	28162770	MOLM13	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	0.1486108650711656	[543]	[435]	1	hSpCas9	negative selection	11538842
128252033	128252056	7	-	28162770	HEL	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.6392965357634928	[106]	[43]	-4	hSpCas9	negative selection	11708199
128254734	128254757	7	+	28162770	HEL	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-1.2958606233355	[91]	[23]	-6	hSpCas9	negative selection	11708200
128252116	128252139	7	-	28162770	HEL	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.4711734721767892	[329]	[292]	4	hSpCas9	negative selection	11708201
128252137	128252160	7	-	28162770	HEL	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.9551957965572615	[702]	[872]	8	hSpCas9	negative selection	11708202
128252005	128252028	7	+	28162770	HEL	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	0.5355899743395672	[474]	[440]	4	hSpCas9	negative selection	11708203
128252019	128252042	7	+	28162770	HEL	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.4635142698202823	[855]	[755]	4	hSpCas9	negative selection	11708204
128254568	128254591	7	-	28162770	HEL	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.5028811684173963	[183]	[166]	4	hSpCas9	negative selection	11708205
128254714	128254737	7	+	28162770	HEL	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	-0.3572611679996429	[373]	[186]	-2	hSpCas9	negative selection	11708206
128254457	128254480	7	-	28162770	HEL	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	0.8441377456829825	[266]	[306]	7	hSpCas9	negative selection	11708207
128254667	128254690	7	+	28162770	HEL	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	0.4105653898713233	[443]	[377]	3	hSpCas9	negative selection	11708208
128252033	128252056	7	-	28162770	MV411	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.6880101421687566	[69]	[94]	6	hSpCas9	negative selection	11877565
128254734	128254757	7	+	28162770	MV411	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-0.2875997246066986	[141]	[97]	-2	hSpCas9	negative selection	11877566
128252116	128252139	7	-	28162770	MV411	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	-0.06770137844194801	[264]	[212]	0	hSpCas9	negative selection	11877567
128252137	128252160	7	-	28162770	MV411	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.8858532555436227	[626]	[975]	7	hSpCas9	negative selection	11877568
128252005	128252028	7	+	28162770	MV411	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	0.7753691064675525	[386]	[557]	7	hSpCas9	negative selection	11877569
128252019	128252042	7	+	28162770	MV411	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.48828171698250333	[676]	[799]	4	hSpCas9	negative selection	11877570
128254568	128254591	7	-	28162770	MV411	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.39225410363455615	[160]	[177]	3	hSpCas9	negative selection	11877571
128254714	128254737	7	+	28162770	MV411	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	-0.4593134303364231	[314]	[192]	-3	hSpCas9	negative selection	11877572
128254457	128254480	7	-	28162770	MV411	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	0.14970074908697817	[228]	[213]	1	hSpCas9	negative selection	11877573
128254667	128254690	7	+	28162770	MV411	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	0.0800592314508094	[282]	[251]	0	hSpCas9	negative selection	11877574
128252033	128252056	7	-	28162770	MONOMAC1	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-0.7913980457829592	[76]	[50]	-6	hSpCas9	negative selection	12046931
128254734	128254757	7	+	28162770	MONOMAC1	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-2.4380449465633487	[51]	[10]	-9	hSpCas9	negative selection	12046932
128252116	128252139	7	-	28162770	MONOMAC1	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.21396513898413339	[178]	[237]	2	hSpCas9	negative selection	12046933
128252137	128252160	7	-	28162770	MONOMAC1	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	-0.0868539293091306	[440]	[475]	0	hSpCas9	negative selection	12046934
128252005	128252028	7	+	28162770	MONOMAC1	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	-0.2161456700072586	[303]	[299]	-2	hSpCas9	negative selection	12046935
128252019	128252042	7	+	28162770	MONOMAC1	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.017087958293293903	[424]	[492]	0	hSpCas9	negative selection	12046936
128254568	128254591	7	-	28162770	MONOMAC1	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-0.4405938783940438	[102]	[86]	-4	hSpCas9	negative selection	12046937
128254714	128254737	7	+	28162770	MONOMAC1	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	0.07859759555387374	[170]	[206]	0	hSpCas9	negative selection	12046938
128254457	128254480	7	-	28162770	MONOMAC1	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	0.6118216655884382	[136]	[239]	6	hSpCas9	negative selection	12046939
128254667	128254690	7	+	28162770	MONOMAC1	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	0.07758553304945193	[185]	[224]	0	hSpCas9	negative selection	12046940
128252033	128252056	7	-	28162770	OCIAML2	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	0.8672398135142227	[8]	[90]	8	hSpCas9	negative selection	12216297
128254734	128254757	7	+	28162770	OCIAML2	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	-1.3331263014922263	[19]	[43]	-7	hSpCas9	negative selection	12216298
128252116	128252139	7	-	28162770	OCIAML2	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.9232843824709285	[42]	[451]	8	hSpCas9	negative selection	12216299
128252137	128252160	7	-	28162770	OCIAML2	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.18770586180921445	[114]	[725]	1	hSpCas9	negative selection	12216300
128252005	128252028	7	+	28162770	OCIAML2	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	0.6337068345725743	[79]	[687]	6	hSpCas9	negative selection	12216301
128252019	128252042	7	+	28162770	OCIAML2	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.662636705621303	[123]	[1087]	6	hSpCas9	negative selection	12216302
128254568	128254591	7	-	28162770	OCIAML2	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	0.367313416648866	[19]	[142]	3	hSpCas9	negative selection	12216303
128254714	128254737	7	+	28162770	OCIAML2	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	0.11433267547899495	[57]	[347]	1	hSpCas9	negative selection	12216304
128254457	128254480	7	-	28162770	OCIAML2	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	1.2068639612328511	[38]	[498]	9	hSpCas9	negative selection	12216305
128254667	128254690	7	+	28162770	OCIAML2	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	0.14535957109961928	[68]	[422]	1	hSpCas9	negative selection	12216306
128252033	128252056	7	-	28162770	OCIAML3	viability	AAAGCCACAAGAATCCGCACAGG	LEP	ENSG00000174697	-2.04651984502167	[25]	[18]	-8	hSpCas9	negative selection	12385663
128254734	128254757	7	+	28162770	OCIAML3	viability	TGGCAGCTGGACCTCAGCCCTGG	LEP	ENSG00000174697	0.07341702058896615	[16]	[53]	0	hSpCas9	negative selection	12385664
128252116	128252139	7	-	28162770	OCIAML3	viability	GGTGACAATTGTCTTGATGAGGG	LEP	ENSG00000174697	0.36946648365072293	[69]	[272]	3	hSpCas9	negative selection	12385665
128252137	128252160	7	-	28162770	OCIAML3	viability	GTGTGAAATGTCATTGATCCTGG	LEP	ENSG00000174697	0.007730573147819886	[170]	[518]	0	hSpCas9	negative selection	12385666
128252005	128252028	7	+	28162770	OCIAML3	viability	TCCTGGGAAGGAAAATGCATTGG	LEP	ENSG00000174697	0.8063333477479786	[110]	[585]	7	hSpCas9	negative selection	12385667
128252019	128252042	7	+	28162770	OCIAML3	viability	ATGCATTGGGGAACCCTGTGCGG	LEP	ENSG00000174697	0.5293747751811189	[167]	[731]	5	hSpCas9	negative selection	12385668
128254568	128254591	7	-	28162770	OCIAML3	viability	GCACGTGAAGAAGATCCCGGAGG	LEP	ENSG00000174697	-1.0400720352236315	[46]	[68]	-6	hSpCas9	negative selection	12385669
128254714	128254737	7	+	28162770	OCIAML3	viability	GGTCTCTGCAGGACATGCTGTGG	LEP	ENSG00000174697	0.1373984285001424	[77]	[258]	1	hSpCas9	negative selection	12385670
128254457	128254480	7	-	28162770	OCIAML3	viability	TGGATAAGGTCAGGATGGGGTGG	LEP	ENSG00000174697	0.03826057517534964	[79]	[247]	0	hSpCas9	negative selection	12385671
128254667	128254690	7	+	28162770	OCIAML3	viability	AGCTTCAGGCTACTCCACAGAGG	LEP	ENSG00000174697	0.06034819581466677	[114]	[361]	0	hSpCas9	negative selection	12385672