Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 4036
• Symbol: LRP2
• Description: LDL receptor related protein 2

DataSource: http://genomecrispr.dkfz.de/#!/results/LRP2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
169279385	169279408	2	-	26472758	Jiyoye	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	2.766256474810702	[22]	[117]	9	hSpCas9	negative selection	92358
169275218	169275241	2	-	26472758	Jiyoye	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	-0.5005661106421382	[211]	[112]	-4	hSpCas9	negative selection	92359
169191964	169191987	2	+	26472758	Jiyoye	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	0.6434097279959519	[162]	[191]	5	hSpCas9	negative selection	92360
169320776	169320799	2	-	26472758	Jiyoye	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	0.3202397447345926	[170]	[160]	2	hSpCas9	negative selection	92361
169292351	169292374	2	-	26472758	Jiyoye	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	1.4300757836159521	[124]	[253]	8	hSpCas9	negative selection	92362
169292338	169292361	2	+	26472758	Jiyoye	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	1.2916981640859373	[129]	[239]	7	hSpCas9	negative selection	92363
169290886	169290909	2	-	26472758	Jiyoye	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	0.5446789052558085	[79]	[87]	4	hSpCas9	negative selection	92364
169289048	169289071	2	+	26472758	Jiyoye	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	2.079600723477369	[15]	[50]	8	hSpCas9	negative selection	92365
169280415	169280438	2	-	26472758	Jiyoye	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	-0.38859156627651886	[216]	[124]	-3	hSpCas9	negative selection	92366
169280392	169280415	2	+	26472758	Jiyoye	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.942842585970256	[128]	[186]	6	hSpCas9	negative selection	92367
169279385	169279408	2	-	26472758	KBM7	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	0.7548985358667887	[454,270]	[329,238]	8	hSpCas9	negative selection	283476
169275218	169275241	2	-	26472758	KBM7	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	0.809551039605985	[402,513]	[556,229]	8	hSpCas9	negative selection	283477
169191964	169191987	2	+	26472758	KBM7	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	0.028762359868534593	[734,430]	[234,307]	0	hSpCas9	negative selection	283478
169320776	169320799	2	-	26472758	KBM7	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	0.072376637545363	[780,486]	[391,231]	0	hSpCas9	negative selection	283479
169292351	169292374	2	-	26472758	KBM7	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	-0.20704075665881871	[1073,517]	[375,258]	-2	hSpCas9	negative selection	283480
169292338	169292361	2	+	26472758	KBM7	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	0.5970640422544595	[940,872]	[593,691]	6	hSpCas9	negative selection	283481
169290886	169290909	2	-	26472758	KBM7	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	-0.06107063113218292	[389,270]	[166,128]	0	hSpCas9	negative selection	283482
169289048	169289071	2	+	26472758	KBM7	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	0.0952636925044863	[397,319]	[184,173]	0	hSpCas9	negative selection	283483
169280415	169280438	2	-	26472758	KBM7	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	0.9685074342689605	[420,269]	[494,148]	9	hSpCas9	negative selection	283484
169280392	169280415	2	+	26472758	KBM7	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.5418123802501987	[1052,668]	[582,574]	6	hSpCas9	negative selection	283485
169279385	169279408	2	-	26472758	Raji	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	0.7491918964994657	[140]	[54]	7	hSpCas9	negative selection	474594
169275218	169275241	2	-	26472758	Raji	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	-0.20615677402104382	[342]	[68]	-2	hSpCas9	negative selection	474595
169191964	169191987	2	+	26472758	Raji	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	-0.3602220147093979	[353]	[63]	-3	hSpCas9	negative selection	474596
169320776	169320799	2	-	26472758	Raji	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	0.916242048021591	[273]	[119]	8	hSpCas9	negative selection	474597
169292351	169292374	2	-	26472758	Raji	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	0.6351889648143929	[368]	[132]	6	hSpCas9	negative selection	474598
169292338	169292361	2	+	26472758	Raji	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	0.7024804132284689	[330]	[124]	6	hSpCas9	negative selection	474599
169290886	169290909	2	-	26472758	Raji	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	0.432478909339645	[181]	[56]	4	hSpCas9	negative selection	474600
169289048	169289071	2	+	26472758	Raji	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	-0.5930561827674928	[207]	[31]	-5	hSpCas9	negative selection	474601
169280415	169280438	2	-	26472758	Raji	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	-0.2992417240890442	[227]	[42]	-3	hSpCas9	negative selection	474602
169280392	169280415	2	+	26472758	Raji	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	-0.05458394428979352	[451]	[100]	0	hSpCas9	negative selection	474603
169279385	169279408	2	-	26472758	K562	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	-0.04437877423242875	[225]	[184]	0	hSpCas9	negative selection	665712
169275218	169275241	2	-	26472758	K562	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	-0.18099791739239615	[371]	[276]	-1	hSpCas9	negative selection	665713
169191964	169191987	2	+	26472758	K562	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	-0.250734813204812	[505]	[358]	-2	hSpCas9	negative selection	665714
169320776	169320799	2	-	26472758	K562	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	-0.06580386656863663	[490]	[395]	0	hSpCas9	negative selection	665715
169292351	169292374	2	-	26472758	K562	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	-0.42627364708059334	[545]	[342]	-3	hSpCas9	negative selection	665716
169292338	169292361	2	+	26472758	K562	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	0.1849422492529481	[618]	[593]	1	hSpCas9	negative selection	665717
169290886	169290909	2	-	26472758	K562	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	0.5234610097006329	[238]	[289]	4	hSpCas9	negative selection	665718
169289048	169289071	2	+	26472758	K562	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	-0.9347501180194854	[273]	[120]	-5	hSpCas9	negative selection	665719
169280415	169280438	2	-	26472758	K562	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	-0.1777291607755869	[338]	[252]	-1	hSpCas9	negative selection	665720
169280392	169280415	2	+	26472758	K562	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.7222390607262842	[488]	[680]	6	hSpCas9	negative selection	665721
169280489	169280512	2	-	26627737	DLD1	viability	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	-1.2034792802698793	[286]	[28,29,54]	-8	hSpCas9	negative selection	809176
169282916	169282939	2	-	26627737	DLD1	viability	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.73428135044497	[708]	[456,293,353]	7	hSpCas9	negative selection	809177
169289089	169289112	2	+	26627737	DLD1	viability	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	1.2195730221980845	[252]	[268,190,104]	9	hSpCas9	negative selection	809178
169294189	169294212	2	+	26627737	DLD1	viability	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.10383968090127565	[410]	[157,114,89]	-1	hSpCas9	negative selection	809179
169320792	169320815	2	-	26627737	DLD1	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.6242649853978904	[1043]	[265,255,127]	-6	hSpCas9	negative selection	809180
169362310	169362333	2	+	26627737	DLD1	viability	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	0.5062562279798462	[146]	[30,92,71]	5	hSpCas9	negative selection	809181
169280489	169280512	2	-	26627737	GBM cells	viability after 5 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	0.033843454971794085	[152]	[77,89]	0	hSpCas9	negative selection	891491
169282916	169282939	2	-	26627737	GBM cells	viability after 5 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.2150467129877287	[448]	[250,307]	3	hSpCas9	negative selection	891492
169289089	169289112	2	+	26627737	GBM cells	viability after 5 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	-0.01989004226633362	[189]	[83,116]	0	hSpCas9	negative selection	891493
169294189	169294212	2	+	26627737	GBM cells	viability after 5 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.07775362128369079	[183]	[85,100]	-1	hSpCas9	negative selection	891494
169320792	169320815	2	-	26627737	GBM cells	viability after 5 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.216072725625176	[605]	[344,409]	3	hSpCas9	negative selection	891495
169362310	169362333	2	+	26627737	GBM cells	viability after 5 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-1.1367100348450356	[81]	[20,18]	-9	hSpCas9	negative selection	891496
169280489	169280512	2	-	26627737	GBM cells	viability after 13 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	0.4533184905347478	[152]	[127,101]	6	hSpCas9	negative selection	973806
169282916	169282939	2	-	26627737	GBM cells	viability after 13 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.529093432822018	[448]	[409,303]	6	hSpCas9	negative selection	973807
169289089	169289112	2	+	26627737	GBM cells	viability after 13 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	-0.07455887308467218	[189]	[98,96]	-1	hSpCas9	negative selection	973808
169294189	169294212	2	+	26627737	GBM cells	viability after 13 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.17277490060307177	[183]	[119,62]	-2	hSpCas9	negative selection	973809
169320792	169320815	2	-	26627737	GBM cells	viability after 13 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.03933772803299762	[605]	[397,288]	0	hSpCas9	negative selection	973810
169362310	169362333	2	+	26627737	GBM cells	viability after 13 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-1.207010083961558	[81]	[10,25]	-8	hSpCas9	negative selection	973811
169280489	169280512	2	-	26627737	GBM cells	viability after 21 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	0.7852927355370434	[152]	[148,137]	7	hSpCas9	negative selection	1056121
169282916	169282939	2	-	26627737	GBM cells	viability after 21 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.4389924265943572	[448]	[337,323]	4	hSpCas9	negative selection	1056122
169289089	169289112	2	+	26627737	GBM cells	viability after 21 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	-0.24741601014417003	[189]	[87,85]	-2	hSpCas9	negative selection	1056123
169294189	169294212	2	+	26627737	GBM cells	viability after 21 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.55704496935628	[183]	[80,55]	-5	hSpCas9	negative selection	1056124
169320792	169320815	2	-	26627737	GBM cells	viability after 21 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.4421577805036989	[605]	[269,216]	-4	hSpCas9	negative selection	1056125
169362310	169362333	2	+	26627737	GBM cells	viability after 21 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-2.3711193011705003	[81]	[5,10]	-9	hSpCas9	negative selection	1056126
169280489	169280512	2	-	26627737	RPE1	viability after 9 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	0.16360556749466104	[310]	[136,72]	1	hSpCas9	negative selection	1138436
169282916	169282939	2	-	26627737	RPE1	viability after 9 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.6255488070964523	[2049]	[942,1050]	4	hSpCas9	negative selection	1138437
169289089	169289112	2	+	26627737	RPE1	viability after 9 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	-2.6292222075422993	[1401]	[42,106]	-9	hSpCas9	negative selection	1138438
169294189	169294212	2	+	26627737	RPE1	viability after 9 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	0.39828417398140953	[443]	[125,256]	2	hSpCas9	negative selection	1138439
169320792	169320815	2	-	26627737	RPE1	viability after 9 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.6195912135774985	[1540]	[704,787]	4	hSpCas9	negative selection	1138440
169362310	169362333	2	+	26627737	RPE1	viability after 9 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-0.4147693857463848	[180]	[45,37]	-3	hSpCas9	negative selection	1138441
169280489	169280512	2	-	26627737	RPE1	viability after 12 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	1.1085670792809035	[310]	[151,209]	6	hSpCas9	negative selection	1220751
169282916	169282939	2	-	26627737	RPE1	viability after 12 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.5549538453057223	[2049]	[932,677]	3	hSpCas9	negative selection	1220752
169289089	169289112	2	+	26627737	RPE1	viability after 12 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	-2.240392832565902	[1401]	[35,125]	-8	hSpCas9	negative selection	1220753
169294189	169294212	2	+	26627737	RPE1	viability after 12 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.033234034763076736	[443]	[135,95]	0	hSpCas9	negative selection	1220754
169320792	169320815	2	-	26627737	RPE1	viability after 12 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.3737793747365564	[1540]	[619,447]	2	hSpCas9	negative selection	1220755
169362310	169362333	2	+	26627737	RPE1	viability after 12 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-0.5555979543657976	[180]	[35,29]	-4	hSpCas9	negative selection	1220756
169280489	169280512	2	-	26627737	RPE1	viability after 15 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	0.8328936295622147	[310]	[116,194]	5	hSpCas9	negative selection	1303066
169282916	169282939	2	-	26627737	RPE1	viability after 15 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.5406042856862894	[2049]	[870,816]	3	hSpCas9	negative selection	1303067
169289089	169289112	2	+	26627737	RPE1	viability after 15 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	-1.8324379713275576	[1401]	[62,157]	-8	hSpCas9	negative selection	1303068
169294189	169294212	2	+	26627737	RPE1	viability after 15 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	0.875601889766278	[443]	[317,145]	5	hSpCas9	negative selection	1303069
169320792	169320815	2	-	26627737	RPE1	viability after 15 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.41683846539116887	[1540]	[584,578]	2	hSpCas9	negative selection	1303070
169362310	169362333	2	+	26627737	RPE1	viability after 15 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-0.20861172991009092	[180]	[26,60]	-1	hSpCas9	negative selection	1303071
169280489	169280512	2	-	26627737	RPE1	viability after 18 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	0.43613858893910284	[310]	[85,142]	2	hSpCas9	negative selection	1385381
169282916	169282939	2	-	26627737	RPE1	viability after 18 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.5213930379799443	[2049]	[839,744]	3	hSpCas9	negative selection	1385382
169289089	169289112	2	+	26627737	RPE1	viability after 18 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	-2.1734028483588044	[1401]	[123,40]	-8	hSpCas9	negative selection	1385383
169294189	169294212	2	+	26627737	RPE1	viability after 18 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	0.5147832976053281	[443]	[176,164]	3	hSpCas9	negative selection	1385384
169320792	169320815	2	-	26627737	RPE1	viability after 18 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.6753551361705495	[1540]	[638,690]	4	hSpCas9	negative selection	1385385
169362310	169362333	2	+	26627737	RPE1	viability after 18 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-1.3260031591257104	[180]	[18,19]	-7	hSpCas9	negative selection	1385386
169280489	169280512	2	-	26627737	HeLa	viability after 8 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	0.1342921883409598	[103]	[88,23,44]	1	hSpCas9	negative selection	1467696
169282916	169282939	2	-	26627737	HeLa	viability after 8 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	-0.21802046415000098	[916]	[290,313,407]	-2	hSpCas9	negative selection	1467697
169289089	169289112	2	+	26627737	HeLa	viability after 8 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	1.1076071130561183	[197]	[196,243,122]	8	hSpCas9	negative selection	1467698
169294189	169294212	2	+	26627737	HeLa	viability after 8 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	0.20814974171334108	[292]	[192,112,145]	2	hSpCas9	negative selection	1467699
169320792	169320815	2	-	26627737	HeLa	viability after 8 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.366576646026189	[636]	[413,378,295]	3	hSpCas9	negative selection	1467700
169362310	169362333	2	+	26627737	HeLa	viability after 8 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-0.2413850522492862	[153]	[34,98,32]	-2	hSpCas9	negative selection	1467701
169280489	169280512	2	-	26627737	HeLa	viability after 12 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	-0.0952969418348546	[103]	[16,30,72]	-1	hSpCas9	negative selection	1550011
169282916	169282939	2	-	26627737	HeLa	viability after 12 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	-0.4707705577317901	[916]	[299,302,214]	-4	hSpCas9	negative selection	1550012
169289089	169289112	2	+	26627737	HeLa	viability after 12 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	1.1203766429650288	[197]	[121,319,74]	7	hSpCas9	negative selection	1550013
169294189	169294212	2	+	26627737	HeLa	viability after 12 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.1620041370388588	[292]	[59,157,99]	-1	hSpCas9	negative selection	1550014
169320792	169320815	2	-	26627737	HeLa	viability after 12 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.00964908121270791	[636]	[154,206,435]	0	hSpCas9	negative selection	1550015
169362310	169362333	2	+	26627737	HeLa	viability after 12 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	0.07003927712124125	[153]	[104,52,44]	0	hSpCas9	negative selection	1550016
169280489	169280512	2	-	26627737	HeLa	viability after 15 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	0.5108201910933354	[103]	[8,107,64]	4	hSpCas9	negative selection	1632326
169282916	169282939	2	-	26627737	HeLa	viability after 15 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	-0.29554132657297705	[916]	[296,402,204]	-3	hSpCas9	negative selection	1632327
169289089	169289112	2	+	26627737	HeLa	viability after 15 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	1.2880035307464377	[197]	[173,301,107]	8	hSpCas9	negative selection	1632328
169294189	169294212	2	+	26627737	HeLa	viability after 15 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	0.08012642037943773	[292]	[144,46,190]	0	hSpCas9	negative selection	1632329
169320792	169320815	2	-	26627737	HeLa	viability after 15 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.43438218956734387	[636]	[409,368,264]	3	hSpCas9	negative selection	1632330
169362310	169362333	2	+	26627737	HeLa	viability after 15 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	0.7363494262916622	[153]	[187,34,87]	6	hSpCas9	negative selection	1632331
169280489	169280512	2	-	26627737	HeLa	viability after 18 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	0.5305996944924367	[103]	[3,93,64]	4	hSpCas9	negative selection	1714641
169282916	169282939	2	-	26627737	HeLa	viability after 18 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	-0.28929496407641664	[916]	[199,335,204]	-2	hSpCas9	negative selection	1714642
169289089	169289112	2	+	26627737	HeLa	viability after 18 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	1.2652183787624844	[197]	[105,255,107]	8	hSpCas9	negative selection	1714643
169294189	169294212	2	+	26627737	HeLa	viability after 18 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	0.10679417084776693	[292]	[100,39,190]	0	hSpCas9	negative selection	1714644
169320792	169320815	2	-	26627737	HeLa	viability after 18 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.4362225767019834	[636]	[261,322,264]	3	hSpCas9	negative selection	1714645
169362310	169362333	2	+	26627737	HeLa	viability after 18 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	0.7326047279287586	[153]	[123,30,87]	6	hSpCas9	negative selection	1714646
169280489	169280512	2	-	26627737	HCT116	viability after 6 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	-1.8873031595077276	[148]	[15,0]	-8	hSpCas9	negative selection	1796956
169282916	169282939	2	-	26627737	HCT116	viability after 6 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.1852782619450004	[1120]	[327,129]	1	hSpCas9	negative selection	1796957
169289089	169289112	2	+	26627737	HCT116	viability after 6 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	-0.1411677964444834	[342]	[6,71]	-1	hSpCas9	negative selection	1796958
169294189	169294212	2	+	26627737	HCT116	viability after 6 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	1.0273663107583995	[352]	[96,121]	5	hSpCas9	negative selection	1796959
169320792	169320815	2	-	26627737	HCT116	viability after 6 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.6986382368103059	[1267]	[532,207]	4	hSpCas9	negative selection	1796960
169362310	169362333	2	+	26627737	HCT116	viability after 6 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	5.0289785960887095	[59]	[811,29]	9	hSpCas9	negative selection	1796961
169280489	169280512	2	-	26627737	HCT116	viability after 8 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	-0.15168654118612956	[164]	[98,77,68]	-2	hSpCas9	negative selection	1879271
169282916	169282939	2	-	26627737	HCT116	viability after 8 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.15639596531757038	[562]	[416,232,387]	1	hSpCas9	negative selection	1879272
169289089	169289112	2	+	26627737	HCT116	viability after 8 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	0.1806796784906776	[243]	[169,177,109]	2	hSpCas9	negative selection	1879273
169294189	169294212	2	+	26627737	HCT116	viability after 8 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.7847593983429829	[368]	[35,148,166]	-7	hSpCas9	negative selection	1879274
169320792	169320815	2	-	26627737	HCT116	viability after 8 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.263399290386197	[637]	[308,280,288]	-3	hSpCas9	negative selection	1879275
169362310	169362333	2	+	26627737	HCT116	viability after 8 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-1.1093684187678126	[143]	[29,25,53]	-8	hSpCas9	negative selection	1879276
169280489	169280512	2	-	26627737	HCT116	viability after 9 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	0.26590157023271677	[148]	[15,72]	2	hSpCas9	negative selection	1961586
169282916	169282939	2	-	26627737	HCT116	viability after 9 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	-0.45275351252262513	[1120]	[335,125]	-3	hSpCas9	negative selection	1961587
169289089	169289112	2	+	26627737	HCT116	viability after 9 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	1.748022642764275	[342]	[291,319]	9	hSpCas9	negative selection	1961588
169294189	169294212	2	+	26627737	HCT116	viability after 9 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	1.3254846584862359	[352]	[214,252]	8	hSpCas9	negative selection	1961589
169320792	169320815	2	-	26627737	HCT116	viability after 9 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.02521844230458936	[1267]	[448,261]	0	hSpCas9	negative selection	1961590
169362310	169362333	2	+	26627737	HCT116	viability after 9 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	2.0485852254146266	[59]	[34,90]	9	hSpCas9	negative selection	1961591
169280489	169280512	2	-	26627737	HCT116	viability after 12 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	-0.6640019912474578	[164]	[53,85,24]	-6	hSpCas9	negative selection	2043901
169282916	169282939	2	-	26627737	HCT116	viability after 12 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	-0.049012735365051796	[562]	[184,333,348]	0	hSpCas9	negative selection	2043902
169289089	169289112	2	+	26627737	HCT116	viability after 12 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	-0.29381177834467814	[243]	[91,66,154]	-3	hSpCas9	negative selection	2043903
169294189	169294212	2	+	26627737	HCT116	viability after 12 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.6032743366982947	[368]	[122,112,146]	-6	hSpCas9	negative selection	2043904
169320792	169320815	2	-	26627737	HCT116	viability after 12 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.1366825559407986	[637]	[339,351,220]	-1	hSpCas9	negative selection	2043905
169362310	169362333	2	+	26627737	HCT116	viability after 12 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-0.13498632603386373	[143]	[39,56,111]	-1	hSpCas9	negative selection	2043906
169280489	169280512	2	-	26627737	HCT116	viability after 15 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	-0.4976050895450569	[164]	[87,57,57]	-5	hSpCas9	negative selection	2126216
169282916	169282939	2	-	26627737	HCT116	viability after 15 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	-0.29171085604089264	[562]	[287,299,207]	-3	hSpCas9	negative selection	2126217
169289089	169289112	2	+	26627737	HCT116	viability after 15 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	-0.2856213499391573	[243]	[225,67,64]	-3	hSpCas9	negative selection	2126218
169294189	169294212	2	+	26627737	HCT116	viability after 15 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.7209923831584564	[368]	[164,85,138]	-6	hSpCas9	negative selection	2126219
169320792	169320815	2	-	26627737	HCT116	viability after 15 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.07982278467634951	[637]	[285,428,317]	-1	hSpCas9	negative selection	2126220
169362310	169362333	2	+	26627737	HCT116	viability after 15 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-0.3327492056741925	[143]	[39,15,136]	-3	hSpCas9	negative selection	2126221
169280489	169280512	2	-	26627737	HCT116	viability after 18 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	-0.6646021750209926	[164]	[69,41,38]	-6	hSpCas9	negative selection	2208531
169282916	169282939	2	-	26627737	HCT116	viability after 18 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	-0.11274121517156044	[562]	[174,258,323]	-1	hSpCas9	negative selection	2208532
169289089	169289112	2	+	26627737	HCT116	viability after 18 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	-0.20082643723669064	[243]	[111,37,164]	-2	hSpCas9	negative selection	2208533
169294189	169294212	2	+	26627737	HCT116	viability after 18 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.650148058335686	[368]	[117,94,129]	-5	hSpCas9	negative selection	2208534
169320792	169320815	2	-	26627737	HCT116	viability after 18 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.6164946358710075	[637]	[257,173,171]	-5	hSpCas9	negative selection	2208535
169362310	169362333	2	+	26627737	HCT116	viability after 18 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-0.5988817502159429	[143]	[26,69,38]	-5	hSpCas9	negative selection	2208536
169362333	169362358	2	-	24717434	HeLa	essential genes for diphteria toxin toxicity	GCTCTCGTCGCCTGCCTAGCGCCGG	LRP2	ENSG00000081479	3.811131223195882	[2041,2443,1614]	[0,31,0]	7	hSpCas9	positive selection	2381070
169362333	169362358	2	-	24717434	HeLa	essential genes for diphteria toxin toxicity	GCTCTCGTCGCCTGCCTAGCGCCGG	LRP2	ENSG00000081479	3.811131223195882	[2041,2443,1614]	[0,31,0]	7	hSpCas9	positive selection	2381071
169362333	169362358	2	-	24717434	HeLa	essential genes for diphteria toxin toxicity	GCTCTCGTCGCCTGCCTAGCGCCGG	LRP2	ENSG00000081479	3.811131223195882	[2041,2443,1614]	[0,31,0]	7	hSpCas9	positive selection	2381072
169362326	169362351	2	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TCGCCTGCCTAGCGCCGGCCAGTGG	LRP2	ENSG00000081479	2.225623942188975	[4126,4376,3879]	[0,20,0]	5	hSpCas9	positive selection	2381073
169362326	169362351	2	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TCGCCTGCCTAGCGCCGGCCAGTGG	LRP2	ENSG00000081479	2.225623942188975	[4126,4376,3879]	[0,20,0]	5	hSpCas9	positive selection	2381074
169362326	169362351	2	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TCGCCTGCCTAGCGCCGGCCAGTGG	LRP2	ENSG00000081479	2.225623942188975	[4126,4376,3879]	[0,20,0]	5	hSpCas9	positive selection	2381075
169320857	169320881	2	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TGACAGTGCGCATTTTCGCTGTGG	LRP2	ENSG00000081479	-0.5457370404460301	[3932,3128,3984]	[0,0,0]	-5	hSpCas9	positive selection	2381076
169320857	169320881	2	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TGACAGTGCGCATTTTCGCTGTGG	LRP2	ENSG00000081479	-0.5457370404460301	[3932,3128,3984]	[0,0,0]	-5	hSpCas9	positive selection	2381077
169320857	169320881	2	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TGACAGTGCGCATTTTCGCTGTGG	LRP2	ENSG00000081479	-0.5457370404460301	[3932,3128,3984]	[0,0,0]	-5	hSpCas9	positive selection	2381078
169362333	169362358	2	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCTCTCGTCGCCTGCCTAGCGCCGG	LRP2	ENSG00000081479	0.3074582842898999	[2041,2443,1614]	[0,0,0]	0	hSpCas9	positive selection	2382334
169362326	169362351	2	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TCGCCTGCCTAGCGCCGGCCAGTGG	LRP2	ENSG00000081479	-0.713455258138368	[4126,4376,3879]	[0,0,0]	-7	hSpCas9	positive selection	2382335
169320857	169320881	2	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGACAGTGCGCATTTTCGCTGTGG	LRP2	ENSG00000081479	-0.5453768630657382	[3932,3128,3984]	[0,0,0]	-6	hSpCas9	positive selection	2382336
169149759	169149782	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCTGTCTCCAAG	LRP2	ENSG00000081479	-0.17877550951857135	[78,119]	[17,20]	0	dCas9-VP64	positive selection	2386065
169335562	169335585	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAGGCCATAG	LRP2	ENSG00000081479	-3.2327828351083694	[281,50]	[1,4]	-9	dCas9-VP64	positive selection	2431286
169278442	169278465	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCCCAGGCTGGAGTGCAGCAG	LRP2	ENSG00000081479	0.9977856233970179	[9,4]	[4,0]	4	dCas9-VP64	positive selection	2435893
169174622	169174645	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTTGGGAGGCTGCAG	LRP2	ENSG00000081479	1.7381005027272516	[41,48]	[11,55]	6	dCas9-VP64	positive selection	2458093
169194817	169194840	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTCAAGTGATTCTCCTGCCTGAG	LRP2	ENSG00000081479	0.04005304646372276	[213,38]	[51,1]	0	dCas9-VP64	positive selection	2478022
169149759	169149782	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCTGTCTCCAAG	LRP2	ENSG00000081479	1.3499530185057784	[84,70]	[54,73]	7	dCas9-VP64	positive selection	2481320
169335562	169335585	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAGGCCATAG	LRP2	ENSG00000081479	0.5850522226976638	[88,64]	[38,35]	4	dCas9-VP64	positive selection	2526541
169278442	169278465	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCCCAGGCTGGAGTGCAGCAG	LRP2	ENSG00000081479	-0.1814090993543942	[50,40]	[18,6]	-2	dCas9-VP64	positive selection	2531148
169174622	169174645	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTTGGGAGGCTGCAG	LRP2	ENSG00000081479	0.27268558780642654	[105,40]	[39,17]	2	dCas9-VP64	positive selection	2553348
169194817	169194840	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTCAAGTGATTCTCCTGCCTGAG	LRP2	ENSG00000081479	-0.7043264998708204	[149,257]	[17,60]	-6	dCas9-VP64	positive selection	2573277
169282944	169282967	2	-	27260157	DLD1	viability	CAGAAGTGTGAAAGCCGACCTGG	LRP2	ENSG00000081479	0.203181079002892	[]	[]	3	hSpCas9	negative selection	2575139
169289085	169289108	2	-	27260157	DLD1	viability	TGCCATGAGACGCCGTATGGAGG	LRP2	ENSG00000081479	-0.43236785339564	[]	[]	-4	hSpCas9	negative selection	2577928
169320818	169320841	2	+	27260157	DLD1	viability	CCATCACACCTCCAGTCTGCAGG	LRP2	ENSG00000081479	0.498870709612308	[]	[]	8	hSpCas9	negative selection	2578356
169362384	169362407	2	-	27260157	DLD1	viability	CGCGGAGATGGATCGCGGGCCGG	LRP2	ENSG00000081479	-0.133776817752639	[]	[]	-1	hSpCas9	negative selection	2579149
169318828	169318851	2	+	27260157	DLD1	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.384185216593664	[]	[]	4	hSpCas9	negative selection	2580971
169294169	169294192	2	+	27260157	DLD1	viability	CGTCTTGGCAATCATTGTCATGG	LRP2	ENSG00000081479	-0.400491390851997	[]	[]	-3	hSpCas9	negative selection	2584547
169362333	169362356	2	-	27260157	DLD1	viability	TCTCGTCGCCTGCCTAGCGCCGG	LRP2	ENSG00000081479	0.521179501151299	[]	[]	8	hSpCas9	negative selection	2584985
169290925	169290948	2	+	27260157	DLD1	viability	GAGATGCATCGTCCCGACTCTGG	LRP2	ENSG00000081479	-0.25980986433631	[]	[]	-2	hSpCas9	negative selection	2607054
169362339	169362362	2	+	27260157	DLD1	viability	CTAGGCAGGCGACGAGAGCCAGG	LRP2	ENSG00000081479	-0.532994331435504	[]	[]	-4	hSpCas9	negative selection	2608161
169289029	169289052	2	+	27260157	DLD1	viability	CACAGGTACGGCTGTCATTGTGG	LRP2	ENSG00000081479	0.221170703220223	[]	[]	3	hSpCas9	negative selection	2612881
169292351	169292374	2	-	27260157	DLD1	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	0.498871957962328	[]	[]	8	hSpCas9	negative selection	2614812
169290937	169290960	2	-	27260157	DLD1	viability	GAATGGTCTTGCCCAGAGTCGGG	LRP2	ENSG00000081479	0.0606921781069897	[]	[]	3	hSpCas9	negative selection	2614891
169289105	169289128	2	+	27260157	DLD1	viability	GCACTGGTACTGGCAGTTCAAGG	LRP2	ENSG00000081479	-0.138302881402854	[]	[]	-1	hSpCas9	negative selection	2616249
169307322	169307345	2	+	27260157	DLD1	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	-0.88998913761979	[]	[]	-6	hSpCas9	negative selection	2618760
169320782	169320805	2	-	27260157	DLD1	viability	TCAGATGACGCGGATGAAATTGG	LRP2	ENSG00000081479	0.100781838274438	[]	[]	3	hSpCas9	negative selection	2619860
169362388	169362411	2	+	27260157	DLD1	viability	CCCGCGATCCATCTCCGCGACGG	LRP2	ENSG00000081479	-0.235522642707596	[]	[]	-2	hSpCas9	negative selection	2620779
169289095	169289118	2	+	27260157	DLD1	viability	GCGTCTCATGGCACTGGTACTGG	LRP2	ENSG00000081479	0.612147817536953	[]	[]	8	hSpCas9	negative selection	2622381
169320792	169320815	2	-	27260157	DLD1	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.585984842835165	[]	[]	8	hSpCas9	negative selection	2641386
169362365	169362388	2	+	27260157	DLD1	viability	AGCGTGCACGCCACTGCTGCCGG	LRP2	ENSG00000081479	-0.667805026813238	[]	[]	-5	hSpCas9	negative selection	2641913
169320793	169320816	2	+	27260157	DLD1	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	-0.441829456391118	[]	[]	-4	hSpCas9	negative selection	2648914
169282944	169282967	2	-	27260157	HT1080	viability	CAGAAGTGTGAAAGCCGACCTGG	LRP2	ENSG00000081479	0.60908614509145	[]	[]	5	hSpCas9	negative selection	2651269
169289085	169289108	2	-	27260157	HT1080	viability	TGCCATGAGACGCCGTATGGAGG	LRP2	ENSG00000081479	-0.0955413741292515	[]	[]	0	hSpCas9	negative selection	2654058
169320818	169320841	2	+	27260157	HT1080	viability	CCATCACACCTCCAGTCTGCAGG	LRP2	ENSG00000081479	0.745299587229856	[]	[]	6	hSpCas9	negative selection	2654486
169362384	169362407	2	-	27260157	HT1080	viability	CGCGGAGATGGATCGCGGGCCGG	LRP2	ENSG00000081479	-0.979824231506374	[]	[]	-8	hSpCas9	negative selection	2655279
169318828	169318851	2	+	27260157	HT1080	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	-0.26307895870395	[]	[]	0	hSpCas9	negative selection	2657101
169294169	169294192	2	+	27260157	HT1080	viability	CGTCTTGGCAATCATTGTCATGG	LRP2	ENSG00000081479	-0.837256293255995	[]	[]	-8	hSpCas9	negative selection	2660677
169362333	169362356	2	-	27260157	HT1080	viability	TCTCGTCGCCTGCCTAGCGCCGG	LRP2	ENSG00000081479	0.1164082132189	[]	[]	1	hSpCas9	negative selection	2661115
169290925	169290948	2	+	27260157	HT1080	viability	GAGATGCATCGTCCCGACTCTGG	LRP2	ENSG00000081479	0.449652486053712	[]	[]	4	hSpCas9	negative selection	2683184
169362339	169362362	2	+	27260157	HT1080	viability	CTAGGCAGGCGACGAGAGCCAGG	LRP2	ENSG00000081479	0.342787825850216	[]	[]	3	hSpCas9	negative selection	2684291
169289029	169289052	2	+	27260157	HT1080	viability	CACAGGTACGGCTGTCATTGTGG	LRP2	ENSG00000081479	-0.448064905249131	[]	[]	-7	hSpCas9	negative selection	2689011
169292351	169292374	2	-	27260157	HT1080	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	0.081996432087595	[]	[]	0	hSpCas9	negative selection	2690942
169290937	169290960	2	-	27260157	HT1080	viability	GAATGGTCTTGCCCAGAGTCGGG	LRP2	ENSG00000081479	-0.119692549516632	[]	[]	0	hSpCas9	negative selection	2691021
169289105	169289128	2	+	27260157	HT1080	viability	GCACTGGTACTGGCAGTTCAAGG	LRP2	ENSG00000081479	0.722033726209206	[]	[]	6	hSpCas9	negative selection	2692379
169307322	169307345	2	+	27260157	HT1080	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.752929037009173	[]	[]	6	hSpCas9	negative selection	2694890
169320782	169320805	2	-	27260157	HT1080	viability	TCAGATGACGCGGATGAAATTGG	LRP2	ENSG00000081479	0.743139511884703	[]	[]	6	hSpCas9	negative selection	2695990
169362388	169362411	2	+	27260157	HT1080	viability	CCCGCGATCCATCTCCGCGACGG	LRP2	ENSG00000081479	0.138939260501885	[]	[]	1	hSpCas9	negative selection	2696909
169289095	169289118	2	+	27260157	HT1080	viability	GCGTCTCATGGCACTGGTACTGG	LRP2	ENSG00000081479	0.451436598850458	[]	[]	4	hSpCas9	negative selection	2698511
169320792	169320815	2	-	27260157	HT1080	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.482626603265479	[]	[]	4	hSpCas9	negative selection	2717516
169362365	169362388	2	+	27260157	HT1080	viability	AGCGTGCACGCCACTGCTGCCGG	LRP2	ENSG00000081479	0.471734513750014	[]	[]	4	hSpCas9	negative selection	2718043
169320793	169320816	2	+	27260157	HT1080	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	-0.543481497916383	[]	[]	-7	hSpCas9	negative selection	2725044
169282944	169282967	2	-	27260157	MKN45	viability	CAGAAGTGTGAAAGCCGACCTGG	LRP2	ENSG00000081479	1.44647752288554	[]	[]	9	hSpCas9	negative selection	2727399
169289085	169289108	2	-	27260157	MKN45	viability	TGCCATGAGACGCCGTATGGAGG	LRP2	ENSG00000081479	-0.0998686798103662	[]	[]	0	hSpCas9	negative selection	2730188
169320818	169320841	2	+	27260157	MKN45	viability	CCATCACACCTCCAGTCTGCAGG	LRP2	ENSG00000081479	0.789664046130218	[]	[]	7	hSpCas9	negative selection	2730616
169362384	169362407	2	-	27260157	MKN45	viability	CGCGGAGATGGATCGCGGGCCGG	LRP2	ENSG00000081479	-0.769278085269624	[]	[]	-7	hSpCas9	negative selection	2731409
169318828	169318851	2	+	27260157	MKN45	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	-0.345234592613512	[]	[]	-1	hSpCas9	negative selection	2733231
169294169	169294192	2	+	27260157	MKN45	viability	CGTCTTGGCAATCATTGTCATGG	LRP2	ENSG00000081479	-0.945293815585488	[]	[]	-7	hSpCas9	negative selection	2736807
169362333	169362356	2	-	27260157	MKN45	viability	TCTCGTCGCCTGCCTAGCGCCGG	LRP2	ENSG00000081479	-0.254983042256555	[]	[]	-1	hSpCas9	negative selection	2737245
169290925	169290948	2	+	27260157	MKN45	viability	GAGATGCATCGTCCCGACTCTGG	LRP2	ENSG00000081479	0.68304970383305	[]	[]	7	hSpCas9	negative selection	2759314
169362339	169362362	2	+	27260157	MKN45	viability	CTAGGCAGGCGACGAGAGCCAGG	LRP2	ENSG00000081479	0.0260813520690261	[]	[]	0	hSpCas9	negative selection	2760421
169289029	169289052	2	+	27260157	MKN45	viability	CACAGGTACGGCTGTCATTGTGG	LRP2	ENSG00000081479	0.15683709688803	[]	[]	5	hSpCas9	negative selection	2765141
169292351	169292374	2	-	27260157	MKN45	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	-0.562853327819971	[]	[]	-6	hSpCas9	negative selection	2767072
169290937	169290960	2	-	27260157	MKN45	viability	GAATGGTCTTGCCCAGAGTCGGG	LRP2	ENSG00000081479	-0.304052486665921	[]	[]	-1	hSpCas9	negative selection	2767151
169289105	169289128	2	+	27260157	MKN45	viability	GCACTGGTACTGGCAGTTCAAGG	LRP2	ENSG00000081479	-0.359251331715046	[]	[]	-1	hSpCas9	negative selection	2768509
169307322	169307345	2	+	27260157	MKN45	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	-0.285083206431285	[]	[]	-1	hSpCas9	negative selection	2771020
169320782	169320805	2	-	27260157	MKN45	viability	TCAGATGACGCGGATGAAATTGG	LRP2	ENSG00000081479	0.925796821249482	[]	[]	8	hSpCas9	negative selection	2772120
169362388	169362411	2	+	27260157	MKN45	viability	CCCGCGATCCATCTCCGCGACGG	LRP2	ENSG00000081479	-0.107489196045915	[]	[]	0	hSpCas9	negative selection	2773039
169289095	169289118	2	+	27260157	MKN45	viability	GCGTCTCATGGCACTGGTACTGG	LRP2	ENSG00000081479	-0.53899895372014	[]	[]	-6	hSpCas9	negative selection	2774641
169320792	169320815	2	-	27260157	MKN45	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.402176352096395	[]	[]	6	hSpCas9	negative selection	2793646
169362365	169362388	2	+	27260157	MKN45	viability	AGCGTGCACGCCACTGCTGCCGG	LRP2	ENSG00000081479	-0.428748896140115	[]	[]	-6	hSpCas9	negative selection	2794173
169320793	169320816	2	+	27260157	MKN45	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	-0.82399390764659	[]	[]	-7	hSpCas9	negative selection	2801174
169282944	169282967	2	-	27260157	RKO	viability	CAGAAGTGTGAAAGCCGACCTGG	LRP2	ENSG00000081479	1.04974210565931	[]	[]	9	hSpCas9	negative selection	2803529
169289085	169289108	2	-	27260157	RKO	viability	TGCCATGAGACGCCGTATGGAGG	LRP2	ENSG00000081479	-0.52662668115504	[]	[]	-6	hSpCas9	negative selection	2806318
169320818	169320841	2	+	27260157	RKO	viability	CCATCACACCTCCAGTCTGCAGG	LRP2	ENSG00000081479	0.618099231736807	[]	[]	3	hSpCas9	negative selection	2806746
169362384	169362407	2	-	27260157	RKO	viability	CGCGGAGATGGATCGCGGGCCGG	LRP2	ENSG00000081479	-0.112531181132446	[]	[]	0	hSpCas9	negative selection	2807539
169318828	169318851	2	+	27260157	RKO	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	-0.0553921692945878	[]	[]	0	hSpCas9	negative selection	2809361
169294169	169294192	2	+	27260157	RKO	viability	CGTCTTGGCAATCATTGTCATGG	LRP2	ENSG00000081479	0.411437282038125	[]	[]	2	hSpCas9	negative selection	2812937
169362333	169362356	2	-	27260157	RKO	viability	TCTCGTCGCCTGCCTAGCGCCGG	LRP2	ENSG00000081479	-0.169525553714143	[]	[]	-1	hSpCas9	negative selection	2813375
169290925	169290948	2	+	27260157	RKO	viability	GAGATGCATCGTCCCGACTCTGG	LRP2	ENSG00000081479	0.466841122268149	[]	[]	2	hSpCas9	negative selection	2835444
169362339	169362362	2	+	27260157	RKO	viability	CTAGGCAGGCGACGAGAGCCAGG	LRP2	ENSG00000081479	0.644037073117046	[]	[]	3	hSpCas9	negative selection	2836551
169289029	169289052	2	+	27260157	RKO	viability	CACAGGTACGGCTGTCATTGTGG	LRP2	ENSG00000081479	0.381959960562275	[]	[]	2	hSpCas9	negative selection	2841271
169292351	169292374	2	-	27260157	RKO	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	0.139271680141655	[]	[]	0	hSpCas9	negative selection	2843202
169290937	169290960	2	-	27260157	RKO	viability	GAATGGTCTTGCCCAGAGTCGGG	LRP2	ENSG00000081479	-0.36348283610074	[]	[]	-6	hSpCas9	negative selection	2843281
169289105	169289128	2	+	27260157	RKO	viability	GCACTGGTACTGGCAGTTCAAGG	LRP2	ENSG00000081479	-0.292909141665841	[]	[]	-6	hSpCas9	negative selection	2844639
169307322	169307345	2	+	27260157	RKO	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	-0.46571317783252	[]	[]	-6	hSpCas9	negative selection	2847150
169320782	169320805	2	-	27260157	RKO	viability	TCAGATGACGCGGATGAAATTGG	LRP2	ENSG00000081479	0.324334614382275	[]	[]	1	hSpCas9	negative selection	2848250
169362388	169362411	2	+	27260157	RKO	viability	CCCGCGATCCATCTCCGCGACGG	LRP2	ENSG00000081479	0.168421028408641	[]	[]	0	hSpCas9	negative selection	2849169
169289095	169289118	2	+	27260157	RKO	viability	GCGTCTCATGGCACTGGTACTGG	LRP2	ENSG00000081479	-0.408816068004346	[]	[]	-6	hSpCas9	negative selection	2850771
169320792	169320815	2	-	27260157	RKO	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.975511605957017	[]	[]	8	hSpCas9	negative selection	2869776
169362365	169362388	2	+	27260157	RKO	viability	AGCGTGCACGCCACTGCTGCCGG	LRP2	ENSG00000081479	0.069866938329688	[]	[]	0	hSpCas9	negative selection	2870303
169320793	169320816	2	+	27260157	RKO	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	-0.198901247926464	[]	[]	-1	hSpCas9	negative selection	2877304
169282944	169282967	2	-	27260157	SF268	viability	CAGAAGTGTGAAAGCCGACCTGG	LRP2	ENSG00000081479	-0.0793681443666595	[]	[]	0	hSpCas9	negative selection	2879659
169289085	169289108	2	-	27260157	SF268	viability	TGCCATGAGACGCCGTATGGAGG	LRP2	ENSG00000081479	-0.201684363501661	[]	[]	-1	hSpCas9	negative selection	2882448
169320818	169320841	2	+	27260157	SF268	viability	CCATCACACCTCCAGTCTGCAGG	LRP2	ENSG00000081479	0.478015191409196	[]	[]	7	hSpCas9	negative selection	2882876
169362384	169362407	2	-	27260157	SF268	viability	CGCGGAGATGGATCGCGGGCCGG	LRP2	ENSG00000081479	-0.496506183952899	[]	[]	-4	hSpCas9	negative selection	2883669
169318828	169318851	2	+	27260157	SF268	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.253574371945801	[]	[]	4	hSpCas9	negative selection	2885491
169294169	169294192	2	+	27260157	SF268	viability	CGTCTTGGCAATCATTGTCATGG	LRP2	ENSG00000081479	-1.18021222474044	[]	[]	-7	hSpCas9	negative selection	2889067
169362333	169362356	2	-	27260157	SF268	viability	TCTCGTCGCCTGCCTAGCGCCGG	LRP2	ENSG00000081479	0.107189155491243	[]	[]	0	hSpCas9	negative selection	2889505
169290925	169290948	2	+	27260157	SF268	viability	GAGATGCATCGTCCCGACTCTGG	LRP2	ENSG00000081479	0.668262740901536	[]	[]	8	hSpCas9	negative selection	2911574
169362339	169362362	2	+	27260157	SF268	viability	CTAGGCAGGCGACGAGAGCCAGG	LRP2	ENSG00000081479	-0.144825975672924	[]	[]	-1	hSpCas9	negative selection	2912681
169289029	169289052	2	+	27260157	SF268	viability	CACAGGTACGGCTGTCATTGTGG	LRP2	ENSG00000081479	0.412430380595948	[]	[]	4	hSpCas9	negative selection	2917401
169292351	169292374	2	-	27260157	SF268	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	-0.205110570053389	[]	[]	-2	hSpCas9	negative selection	2919332
169290937	169290960	2	-	27260157	SF268	viability	GAATGGTCTTGCCCAGAGTCGGG	LRP2	ENSG00000081479	-0.267993625081028	[]	[]	-2	hSpCas9	negative selection	2919411
169289105	169289128	2	+	27260157	SF268	viability	GCACTGGTACTGGCAGTTCAAGG	LRP2	ENSG00000081479	0.330269699066048	[]	[]	4	hSpCas9	negative selection	2920769
169307322	169307345	2	+	27260157	SF268	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	-0.137623678448758	[]	[]	-1	hSpCas9	negative selection	2923280
169320782	169320805	2	-	27260157	SF268	viability	TCAGATGACGCGGATGAAATTGG	LRP2	ENSG00000081479	1.09505280159195	[]	[]	9	hSpCas9	negative selection	2924380
169362388	169362411	2	+	27260157	SF268	viability	CCCGCGATCCATCTCCGCGACGG	LRP2	ENSG00000081479	0.776560044482052	[]	[]	8	hSpCas9	negative selection	2925299
169289095	169289118	2	+	27260157	SF268	viability	GCGTCTCATGGCACTGGTACTGG	LRP2	ENSG00000081479	0.386679663171868	[]	[]	4	hSpCas9	negative selection	2926901
169320792	169320815	2	-	27260157	SF268	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.724091925506639	[]	[]	8	hSpCas9	negative selection	2945906
169362365	169362388	2	+	27260157	SF268	viability	AGCGTGCACGCCACTGCTGCCGG	LRP2	ENSG00000081479	-0.560888281735907	[]	[]	-4	hSpCas9	negative selection	2946433
169320793	169320816	2	+	27260157	SF268	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	-0.664618078217791	[]	[]	-5	hSpCas9	negative selection	2953434
169246950	169246973	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATCAACCCACGCATCCTAACGG	LRP2	ENSG00000081479	-0.011579429216326896	[3,3]	[2,2]	0	hSpCas9	positive selection	2999992
169233511	169233534	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.16914954585863862	[2,2]	[3,1]	3	hSpCas9	positive selection	2999993
169294191	169294214	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCACAGACATAAGCACGAGGG	LRP2	ENSG00000081479	-0.5787548576181095	[3,2]	[1,1]	-7	hSpCas9	positive selection	2999994
169207159	169207182	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGACTTTAAGAAGAACACGGCGG	LRP2	ENSG00000081479	-0.05639945763518578	[3,3]	[2,2]	-1	hSpCas9	positive selection	2999995
169246950	169246973	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATCAACCCACGCATCCTAACGG	LRP2	ENSG00000081479	0.1294052549729699	[3,3]	[4,1]	2	hSpCas9	positive selection	3067850
169233511	169233534	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.597716831514735	[2,2]	[4,2]	8	hSpCas9	positive selection	3067851
169294191	169294214	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCACAGACATAAGCACGAGGG	LRP2	ENSG00000081479	-1.105523962711171	[3,3]	[1,0]	-9	hSpCas9	positive selection	3067852
169207159	169207182	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGACTTTAAGAAGAACACGGCGG	LRP2	ENSG00000081479	0.1971791864529526	[3,3]	[3,2]	3	hSpCas9	positive selection	3067853
169320792	169320815		-	24336571	A375	resistance to PLX after 7 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.0718131611938608	[11,12]	[12,12]	2	hSpCas9	positive selection	3125200
169320793	169320816		+	24336571	A375	resistance to PLX after 7 days	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.14915851523896584	[26,24]	[30,26]	5	hSpCas9	positive selection	3125201
169320857	169320880		-	24336571	A375	resistance to PLX after 7 days	GACAGTGCGCATTTTCGCTGTGG	LRP2	ENSG00000081479	0.01533916912558797	[25,26]	[26,26]	0	hSpCas9	positive selection	3125202
169318828	169318851		+	24336571	A375	resistance to PLX after 7 days	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.0036335933166457	[21,21]	[18,24]	0	hSpCas9	positive selection	3125203
169320792	169320815		-	24336571	A375	resistance to PLX after 14 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.2411126684060334	[9,12]	[5,5]	2	hSpCas9	positive selection	3182993
169320793	169320816		+	24336571	A375	resistance to PLX after 14 days	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	-0.44728107451724775	[35,23]	[11,7]	-5	hSpCas9	positive selection	3182994
169320857	169320880		-	24336571	A375	resistance to PLX after 14 days	GACAGTGCGCATTTTCGCTGTGG	LRP2	ENSG00000081479	-0.13731922748213377	[16,22]	[8,7]	-1	hSpCas9	positive selection	3182995
169318828	169318851		+	24336571	A375	resistance to PLX after 14 days	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	-0.11782901873423057	[19,23]	[9,7]	-1	hSpCas9	positive selection	3182996
169320792	169320815		-	24336571	A375	viability after 7 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.13063621956646349	[11]	[11,12]	2	hSpCas9	negative selection	3240786
169320793	169320816		+	24336571	A375	viability after 7 days	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.4175642664214366	[20]	[26,24]	6	hSpCas9	negative selection	3240787
169320857	169320880		-	24336571	A375	viability after 7 days	GACAGTGCGCATTTTCGCTGTGG	LRP2	ENSG00000081479	0.6942445422444901	[16]	[25,26]	9	hSpCas9	negative selection	3240788
169318828	169318851		+	24336571	A375	viability after 7 days	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.539933994999193	[15]	[21,21]	7	hSpCas9	negative selection	3240789
169320792	169320815		-	24336571	A375	viability after 14 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.044378247621857075	[11]	[9,12]	0	hSpCas9	negative selection	3298579
169320793	169320816		+	24336571	A375	viability after 14 days	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.598568359564733	[20]	[35,23]	7	hSpCas9	negative selection	3298580
169320857	169320880		-	24336571	A375	viability after 14 days	GACAGTGCGCATTTTCGCTGTGG	LRP2	ENSG00000081479	0.32510180365993385	[16]	[16,22]	4	hSpCas9	negative selection	3298581
169318828	169318851		+	24336571	A375	viability after 14 days	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.5449410620531774	[15]	[19,23]	7	hSpCas9	negative selection	3298582
169307322	169307345	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	-1.0234445586847676	[310,310]	[0,0]	-7	hSpCas9	positive selection	3377569
169318864	169318887	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	-1.3756689856971227	[396,396]	[0,0]	-8	hSpCas9	positive selection	3377570
169318828	169318851	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	-1.338863544698575	[386,386]	[0,0]	-8	hSpCas9	positive selection	3377571
169246950	169246973	2	-	26780180	HT29	viability (Avana library 4 designs)	AATCAACCCACGCATCCTAACGG	LRP2	ENSG00000081479	1.72927441187588	[]	[]	6	hSpCas9	negative selection	3437561
169233510	169233533	2	+	26780180	HT29	viability (Avana library 4 designs)	GCATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	1.70585174543858	[]	[]	6	hSpCas9	negative selection	3437562
169294190	169294213	2	+	26780180	HT29	viability (Avana library 4 designs)	GGTCACAGACATAAGCACGAGGG	LRP2	ENSG00000081479	1.84465418744427	[]	[]	7	hSpCas9	negative selection	3437563
169207158	169207181	2	+	26780180	HT29	viability (Avana library 4 designs)	TGACTTTAAGAAGAACACGGCGG	LRP2	ENSG00000081479	1.43282527283125	[]	[]	5	hSpCas9	negative selection	3437564
169207158	169207181	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGACTTTAAGAAGAACACGGCGG	LRP2	ENSG00000081479	-5.71615752501712	[]	[]	-6	hSpCas9	negative selection	3526343
169246950	169246973	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATCAACCCACGCATCCTAACGG	LRP2	ENSG00000081479	2.1281584853307	[]	[]	3	hSpCas9	negative selection	3526344
169294190	169294213	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCACAGACATAAGCACGAGGG	LRP2	ENSG00000081479	-5.22431084854087	[]	[]	-5	hSpCas9	negative selection	3526345
169233510	169233533	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	3.72668170748985	[]	[]	6	hSpCas9	negative selection	3526346
169235940	169235963	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TAGTCAATAGTTAAGCCGCAGGG	LRP2	ENSG00000081479	-0.891423187202588	[]	[]	-1	hSpCas9	negative selection	3526347
169213852	169213875	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTAGATTGAAAGAGGAAACGTGG	LRP2	ENSG00000081479	-0.641447566505602	[]	[]	-1	hSpCas9	negative selection	3526348
169207158	169207181	2	+	26780180	A375	viability (Avana lentiGuide)	TGACTTTAAGAAGAACACGGCGG	LRP2	ENSG00000081479	-1.58050916272236	[]	[]	-3	hSpCas9	negative selection	3635002
169246950	169246973	2	-	26780180	A375	viability (Avana lentiGuide)	AATCAACCCACGCATCCTAACGG	LRP2	ENSG00000081479	-2.34085678650149	[]	[]	-4	hSpCas9	negative selection	3635003
169294190	169294213	2	+	26780180	A375	viability (Avana lentiGuide)	GGTCACAGACATAAGCACGAGGG	LRP2	ENSG00000081479	-1.05686381784679	[]	[]	-2	hSpCas9	negative selection	3635004
169233510	169233533	2	+	26780180	A375	viability (Avana lentiGuide)	GCATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	7.49715262467974	[]	[]	6	hSpCas9	negative selection	3635005
169235940	169235963	2	+	26780180	A375	viability (Avana lentiGuide)	TAGTCAATAGTTAAGCCGCAGGG	LRP2	ENSG00000081479	-3.52261282996788	[]	[]	-6	hSpCas9	negative selection	3635006
169213852	169213875	2	-	26780180	A375	viability (Avana lentiGuide)	TTAGATTGAAAGAGGAAACGTGG	LRP2	ENSG00000081479	-0.150059620147475	[]	[]	0	hSpCas9	negative selection	3635007
169207158	169207181	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGACTTTAAGAAGAACACGGCGG	LRP2	ENSG00000081479	-0.6711236050819394	[5]	[4,2]	-7	hSpCas9	positive selection	3743661
169246950	169246973	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATCAACCCACGCATCCTAACGG	LRP2	ENSG00000081479	-0.1415400899947884	[5]	[5,3]	-2	hSpCas9	positive selection	3743662
169294190	169294213	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCACAGACATAAGCACGAGGG	LRP2	ENSG00000081479	-0.5557817180575817	[4]	[2,2]	-7	hSpCas9	positive selection	3743663
169233510	169233533	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.3458716074796687	[4]	[5,5]	9	hSpCas9	positive selection	3743664
169235940	169235963	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TAGTCAATAGTTAAGCCGCAGGG	LRP2	ENSG00000081479	-0.11046854616059221	[6]	[5,5]	-2	hSpCas9	positive selection	3743665
169213852	169213875	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAGATTGAAAGAGGAAACGTGG	LRP2	ENSG00000081479	-0.024207825075575673	[6]	[5,5]	0	hSpCas9	positive selection	3743666
169207158	169207181	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGACTTTAAGAAGAACACGGCGG	LRP2	ENSG00000081479	0.11135994355288041	[5]	[4,5]	2	hSpCas9	positive selection	3852268
169246950	169246973	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATCAACCCACGCATCCTAACGG	LRP2	ENSG00000081479	0.0007097933680053695	[5]	[4,3]	0	hSpCas9	positive selection	3852269
169294190	169294213	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCACAGACATAAGCACGAGGG	LRP2	ENSG00000081479	-0.06192959975583115	[4]	[2,4]	-1	hSpCas9	positive selection	3852270
169233510	169233533	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.17201696393673765	[4]	[4,4]	4	hSpCas9	positive selection	3852271
169235940	169235963	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TAGTCAATAGTTAAGCCGCAGGG	LRP2	ENSG00000081479	0.34941909331196747	[5]	[5,5]	8	hSpCas9	positive selection	3852272
169213852	169213875	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAGATTGAAAGAGGAAACGTGG	LRP2	ENSG00000081479	0.39939980452005647	[5]	[6,5]	9	hSpCas9	positive selection	3852273
169318864	169318887	2	-	26780180	A375	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.902165692947379	[]	[]	4	hSpCas9	negative selection	3957920
169320792	169320815	2	-	26780180	A375	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	1.20545980997969	[]	[]	6	hSpCas9	negative selection	3957921
169307301	169307324	2	-	26780180	A375	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.892646127775558	[]	[]	4	hSpCas9	negative selection	3957922
169320793	169320816	2	+	26780180	A375	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.564243747237104	[]	[]	1	hSpCas9	negative selection	3957923
169318828	169318851	2	+	26780180	A375	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.351213852286899	[]	[]	0	hSpCas9	negative selection	3957924
169307322	169307345	2	+	26780180	A375	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.816457821392075	[]	[]	3	hSpCas9	negative selection	3957925
169318864	169318887	2	-	26780180	HT29	viability (GeCKOv2 library)	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.719166970220649	[]	[]	2	hSpCas9	negative selection	4065886
169320792	169320815	2	-	26780180	HT29	viability (GeCKOv2 library)	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.751840413168516	[]	[]	3	hSpCas9	negative selection	4065887
169307301	169307324	2	-	26780180	HT29	viability (GeCKOv2 library)	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	1.09620731003749	[]	[]	5	hSpCas9	negative selection	4065888
169320793	169320816	2	+	26780180	HT29	viability (GeCKOv2 library)	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.329045421331569	[]	[]	0	hSpCas9	negative selection	4065889
169318828	169318851	2	+	26780180	HT29	viability (GeCKOv2 library)	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.927023750608338	[]	[]	4	hSpCas9	negative selection	4065890
169307322	169307345	2	+	26780180	HT29	viability (GeCKOv2 library)	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.683102545142736	[]	[]	2	hSpCas9	negative selection	4065891
169320792	169320815	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.10244166030319665	[3]	[1,2]	2	hSpCas9	positive selection	4149315
169320793	169320816	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.13361946566257382	[4]	[3,3]	3	hSpCas9	positive selection	4149316
169320857	169320880	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACAGTGCGCATTTTCGCTGTGG	LRP2	ENSG00000081479	-0.06799975306915851	[4]	[2,2]	-1	hSpCas9	positive selection	4149317
169318828	169318851	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	-0.049172523003497504	[4]	[2,3]	-1	hSpCas9	positive selection	4149318
169320792	169320815	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.9098892623975894	[4]	[4,0,3,4]	6	hSpCas9	positive selection	4213337
169320793	169320816	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.9905458721280815	[4]	[4,3,3,3]	7	hSpCas9	positive selection	4213338
169320857	169320880	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACAGTGCGCATTTTCGCTGTGG	LRP2	ENSG00000081479	0.8917096884431857	[3]	[0,4,0,3]	6	hSpCas9	positive selection	4213339
169318828	169318851	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	1.054886440879001	[4]	[3,4,1,4]	7	hSpCas9	positive selection	4213340
169307301	169307324	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.22763270620820605	[2]	[3,1]	4	hSpCas9	positive selection	4280871
169320793	169320816	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.44399433909466895	[3]	[4,3]	8	hSpCas9	positive selection	4280872
169320792	169320815	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.10634647159782074	[2]	[2,1]	-2	hSpCas9	positive selection	4280873
169307322	169307345	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.3704164112252504	[3]	[3,3]	7	hSpCas9	positive selection	4345130
169318864	169318887	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.5028585693264644	[3]	[4,4]	9	hSpCas9	positive selection	4345131
169318828	169318851	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.21535458147598158	[3]	[4,3]	4	hSpCas9	positive selection	4345132
169233511	169233533	2	+	27760321	OCIAML3	viability	CATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.4604717619020614	[697,641]	[581,901]	5	hSpCas9	negative selection	4415139
169239568	169239590	2	-	27760321	OCIAML3	viability	TCCGGTGCTCGTGTGATACAGG	LRP2	ENSG00000081479	-0.3973453792600692	[462,387]	[176,348]	-4	hSpCas9	negative selection	4415140
169247466	169247488	2	-	27760321	OCIAML3	viability	GGGTGCCATTATTCGAGTCAGG	LRP2	ENSG00000081479	0.1720767600146522	[550,489]	[394,539]	2	hSpCas9	negative selection	4415141
169257115	169257137	2	+	27760321	OCIAML3	viability	CCTACTTACGCCCAATCGATGG	LRP2	ENSG00000081479	0.12907426046542048	[1024,809]	[787,768]	1	hSpCas9	negative selection	4415142
169259036	169259058	2	+	27760321	OCIAML3	viability	ATGAACTACCACCGACCGTGGG	LRP2	ENSG00000081479	-0.07830156332343619	[864,721]	[442,770]	-1	hSpCas9	negative selection	4415143
169233511	169233533	2	+	27760321	OCIAML2	viability	CATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	-0.08688203954259865	[697,641]	[410,640]	-1	hSpCas9	negative selection	4498602
169239568	169239590	2	-	27760321	OCIAML2	viability	TCCGGTGCTCGTGTGATACAGG	LRP2	ENSG00000081479	0.1690515124073492	[462,387]	[315,476]	2	hSpCas9	negative selection	4498603
169247466	169247488	2	-	27760321	OCIAML2	viability	GGGTGCCATTATTCGAGTCAGG	LRP2	ENSG00000081479	-0.0988959057097511	[550,489]	[392,391]	-1	hSpCas9	negative selection	4498604
169257115	169257137	2	+	27760321	OCIAML2	viability	CCTACTTACGCCCAATCGATGG	LRP2	ENSG00000081479	0.39955618625735334	[1024,809]	[804,1193]	5	hSpCas9	negative selection	4498605
169259036	169259058	2	+	27760321	OCIAML2	viability	ATGAACTACCACCGACCGTGGG	LRP2	ENSG00000081479	0.3367466878476193	[864,721]	[736,899]	4	hSpCas9	negative selection	4498606
169233511	169233533	2	+	27760321	MV411	viability	CATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.608353163289112	[697,641]	[362,1140]	4	hSpCas9	negative selection	4582065
169239568	169239590	2	-	27760321	MV411	viability	TCCGGTGCTCGTGTGATACAGG	LRP2	ENSG00000081479	-0.49817290865720304	[462,387]	[213,173]	-3	hSpCas9	negative selection	4582066
169247466	169247488	2	-	27760321	MV411	viability	GGGTGCCATTATTCGAGTCAGG	LRP2	ENSG00000081479	0.270475587903231	[550,489]	[260,642]	2	hSpCas9	negative selection	4582067
169257115	169257137	2	+	27760321	MV411	viability	CCTACTTACGCCCAATCGATGG	LRP2	ENSG00000081479	0.8693328800636724	[1024,809]	[927,1355]	6	hSpCas9	negative selection	4582068
169259036	169259058	2	+	27760321	MV411	viability	ATGAACTACCACCGACCGTGGG	LRP2	ENSG00000081479	-0.22405587146114248	[864,721]	[525,326]	-2	hSpCas9	negative selection	4582069
169233511	169233533	2	+	27760321	HL60	viability	CATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.37131810504398255	[697,641]	[785,624]	4	hSpCas9	negative selection	4665528
169239568	169239590	2	-	27760321	HL60	viability	TCCGGTGCTCGTGTGATACAGG	LRP2	ENSG00000081479	-0.2596728054447279	[462,387]	[261,317]	-3	hSpCas9	negative selection	4665529
169247466	169247488	2	-	27760321	HL60	viability	GGGTGCCATTATTCGAGTCAGG	LRP2	ENSG00000081479	0.3797657058046693	[550,489]	[481,626]	5	hSpCas9	negative selection	4665530
169257115	169257137	2	+	27760321	HL60	viability	CCTACTTACGCCCAATCGATGG	LRP2	ENSG00000081479	0.10509943045654158	[1024,809]	[784,817]	1	hSpCas9	negative selection	4665531
169259036	169259058	2	+	27760321	HL60	viability	ATGAACTACCACCGACCGTGGG	LRP2	ENSG00000081479	-0.5664805381768578	[864,721]	[415,456]	-6	hSpCas9	negative selection	4665532
169233511	169233533	2	+	27760321	HT1080	viability	CATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	1.2237439560632979	[641,500]	[430,641]	6	hSpCas9	negative selection	4748991
169239568	169239590	2	-	27760321	HT1080	viability	TCCGGTGCTCGTGTGATACAGG	LRP2	ENSG00000081479	-1.441846012174666	[387,302]	[11,92]	-5	hSpCas9	negative selection	4748992
169247466	169247488	2	-	27760321	HT1080	viability	GGGTGCCATTATTCGAGTCAGG	LRP2	ENSG00000081479	0.03558265707801217	[489,382]	[193,160]	0	hSpCas9	negative selection	4748993
169257115	169257137	2	+	27760321	HT1080	viability	CCTACTTACGCCCAATCGATGG	LRP2	ENSG00000081479	1.522870246079804	[809,631]	[969,666]	8	hSpCas9	negative selection	4748994
169259036	169259058	2	+	27760321	HT1080	viability	ATGAACTACCACCGACCGTGGG	LRP2	ENSG00000081479	1.06347156549897	[721,563]	[732,318]	6	hSpCas9	negative selection	4748995
169233511	169233533	2	+	27760321	HT29	viability after 7 days	CATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.07175145312477837	[641,500]	[681,760,856]	1	hSpCas9	negative selection	4832454
169239568	169239590	2	-	27760321	HT29	viability after 7 days	TCCGGTGCTCGTGTGATACAGG	LRP2	ENSG00000081479	-0.7122951196924482	[387,302]	[357,278,190]	-7	hSpCas9	negative selection	4832455
169247466	169247488	2	-	27760321	HT29	viability after 7 days	GGGTGCCATTATTCGAGTCAGG	LRP2	ENSG00000081479	0.07269133903809233	[489,382]	[448,652,645]	1	hSpCas9	negative selection	4832456
169257115	169257137	2	+	27760321	HT29	viability after 7 days	CCTACTTACGCCCAATCGATGG	LRP2	ENSG00000081479	0.3919647968678237	[809,631]	[1401,1156,1117]	6	hSpCas9	negative selection	4832457
169259036	169259058	2	+	27760321	HT29	viability after 7 days	ATGAACTACCACCGACCGTGGG	LRP2	ENSG00000081479	0.2328739209806212	[721,563]	[1102,981,850]	3	hSpCas9	negative selection	4832458
169233511	169233533	2	+	27760321	HT29	viability after 25 days	CATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.10658958885391345	[641,500]	[679,631,808]	1	hSpCas9	negative selection	4915917
169239568	169239590	2	-	27760321	HT29	viability after 25 days	TCCGGTGCTCGTGTGATACAGG	LRP2	ENSG00000081479	-0.03898700436131586	[387,302]	[298,239,645]	0	hSpCas9	negative selection	4915918
169247466	169247488	2	-	27760321	HT29	viability after 25 days	GGGTGCCATTATTCGAGTCAGG	LRP2	ENSG00000081479	0.08723725263749404	[489,382]	[492,520,582]	0	hSpCas9	negative selection	4915919
169257115	169257137	2	+	27760321	HT29	viability after 25 days	CCTACTTACGCCCAATCGATGG	LRP2	ENSG00000081479	0.5026501213441599	[809,631]	[1065,1021,1447]	5	hSpCas9	negative selection	4915920
169259036	169259058	2	+	27760321	HT29	viability after 25 days	ATGAACTACCACCGACCGTGGG	LRP2	ENSG00000081479	0.37424428557064227	[721,563]	[943,801,1128]	4	hSpCas9	negative selection	4915921
169233511	169233533	2	+	27760321	HT29	viability after 22 days	CATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.4052496234681897	[641,500]	[780,1111,732]	4	hSpCas9	negative selection	4999380
169239568	169239590	2	-	27760321	HT29	viability after 22 days	TCCGGTGCTCGTGTGATACAGG	LRP2	ENSG00000081479	-0.15346108587363694	[387,302]	[359,183,534]	-1	hSpCas9	negative selection	4999381
169247466	169247488	2	-	27760321	HT29	viability after 22 days	GGGTGCCATTATTCGAGTCAGG	LRP2	ENSG00000081479	-0.3318692055730832	[489,382]	[479,394,324]	-3	hSpCas9	negative selection	4999382
169257115	169257137	2	+	27760321	HT29	viability after 22 days	CCTACTTACGCCCAATCGATGG	LRP2	ENSG00000081479	0.5217031337964761	[809,631]	[1121,1251,1217]	6	hSpCas9	negative selection	4999383
169259036	169259058	2	+	27760321	HT29	viability after 22 days	ATGAACTACCACCGACCGTGGG	LRP2	ENSG00000081479	0.2494798393961739	[721,563]	[936,689,1023]	2	hSpCas9	negative selection	4999384
169233511	169233533	2	+	27760321	HT29	viability after 19 days	CATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	-0.359351509980119	[641,500]	[532,337,653]	-3	hSpCas9	negative selection	5082843
169239568	169239590	2	-	27760321	HT29	viability after 19 days	TCCGGTGCTCGTGTGATACAGG	LRP2	ENSG00000081479	-0.139585444880793	[387,302]	[493,208,385]	-1	hSpCas9	negative selection	5082844
169247466	169247488	2	-	27760321	HT29	viability after 19 days	GGGTGCCATTATTCGAGTCAGG	LRP2	ENSG00000081479	0.4494214343904846	[489,382]	[803,449,798]	4	hSpCas9	negative selection	5082845
169257115	169257137	2	+	27760321	HT29	viability after 19 days	CCTACTTACGCCCAATCGATGG	LRP2	ENSG00000081479	0.4762404245503358	[809,631]	[1191,1476,789]	5	hSpCas9	negative selection	5082846
169259036	169259058	2	+	27760321	HT29	viability after 19 days	ATGAACTACCACCGACCGTGGG	LRP2	ENSG00000081479	0.42017072697299085	[721,563]	[1057,561,1325]	4	hSpCas9	negative selection	5082847
169233511	169233533	2	+	27760321	HT29	viability after 16 days	CATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.3620667610863826	[641,500]	[663,910,872]	4	hSpCas9	negative selection	5166306
169239568	169239590	2	-	27760321	HT29	viability after 16 days	TCCGGTGCTCGTGTGATACAGG	LRP2	ENSG00000081479	0.3093365068489754	[387,302]	[530,472,437]	3	hSpCas9	negative selection	5166307
169247466	169247488	2	-	27760321	HT29	viability after 16 days	GGGTGCCATTATTCGAGTCAGG	LRP2	ENSG00000081479	-0.6673508162336892	[489,382]	[437,263,233]	-6	hSpCas9	negative selection	5166308
169257115	169257137	2	+	27760321	HT29	viability after 16 days	CCTACTTACGCCCAATCGATGG	LRP2	ENSG00000081479	0.4552753062649675	[809,631]	[959,1100,1242]	5	hSpCas9	negative selection	5166309
169259036	169259058	2	+	27760321	HT29	viability after 16 days	ATGAACTACCACCGACCGTGGG	LRP2	ENSG00000081479	-0.06664032128773656	[721,563]	[824,525,726]	0	hSpCas9	negative selection	5166310
169233511	169233533	2	+	27760321	HT29	viability after 13 days	CATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.3597669008269164	[641,500]	[771,940,839]	4	hSpCas9	negative selection	5249769
169239568	169239590	2	-	27760321	HT29	viability after 13 days	TCCGGTGCTCGTGTGATACAGG	LRP2	ENSG00000081479	-0.3437997551091986	[387,302]	[374,250,320]	-4	hSpCas9	negative selection	5249770
169247466	169247488	2	-	27760321	HT29	viability after 13 days	GGGTGCCATTATTCGAGTCAGG	LRP2	ENSG00000081479	0.043918489922425696	[489,382]	[485,570,509]	0	hSpCas9	negative selection	5249771
169257115	169257137	2	+	27760321	HT29	viability after 13 days	CCTACTTACGCCCAATCGATGG	LRP2	ENSG00000081479	0.22084469813337781	[809,631]	[845,1129,949]	2	hSpCas9	negative selection	5249772
169259036	169259058	2	+	27760321	HT29	viability after 13 days	ATGAACTACCACCGACCGTGGG	LRP2	ENSG00000081479	0.160871568309636	[721,563]	[857,796,845]	2	hSpCas9	negative selection	5249773
169233511	169233533	2	+	27760321	HT29	viability after 10 days	CATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.17478760652082992	[641,500]	[830,869,718]	2	hSpCas9	negative selection	5333232
169239568	169239590	2	-	27760321	HT29	viability after 10 days	TCCGGTGCTCGTGTGATACAGG	LRP2	ENSG00000081479	-0.11117669083592234	[387,302]	[561,243,387]	-1	hSpCas9	negative selection	5333233
169247466	169247488	2	-	27760321	HT29	viability after 10 days	GGGTGCCATTATTCGAGTCAGG	LRP2	ENSG00000081479	0.09075762171392199	[489,382]	[535,515,684]	1	hSpCas9	negative selection	5333234
169257115	169257137	2	+	27760321	HT29	viability after 10 days	CCTACTTACGCCCAATCGATGG	LRP2	ENSG00000081479	0.023950053280402228	[809,631]	[703,956,1081]	0	hSpCas9	negative selection	5333235
169259036	169259058	2	+	27760321	HT29	viability after 10 days	ATGAACTACCACCGACCGTGGG	LRP2	ENSG00000081479	0.04978781537264665	[721,563]	[735,892,864]	0	hSpCas9	negative selection	5333236
169233511	169233533	2	+	27760321	MOLM13	viability	CATAACCCGACGAGTAGCACGG	LRP2	ENSG00000081479	0.3245258632488409	[697,641]	[623,344]	2	hSpCas9	negative selection	5416695
169239568	169239590	2	-	27760321	MOLM13	viability	TCCGGTGCTCGTGTGATACAGG	LRP2	ENSG00000081479	0.29737360865974966	[462,387]	[120,440]	2	hSpCas9	negative selection	5416696
169247466	169247488	2	-	27760321	MOLM13	viability	GGGTGCCATTATTCGAGTCAGG	LRP2	ENSG00000081479	-0.5314218983654917	[550,489]	[244,166]	-3	hSpCas9	negative selection	5416697
169257115	169257137	2	+	27760321	MOLM13	viability	CCTACTTACGCCCAATCGATGG	LRP2	ENSG00000081479	0.9327311760987602	[1024,809]	[1608,447]	6	hSpCas9	negative selection	5416698
169259036	169259058	2	+	27760321	MOLM13	viability	ATGAACTACCACCGACCGTGGG	LRP2	ENSG00000081479	0.3117250998867114	[864,721]	[749,385]	2	hSpCas9	negative selection	5416699
169362416	169362439	2	+	27661255	K562	viability	GGCCTCGCCGTTCCTTCCCCGGG	LRP2	ENSG00000081479	0.13649616107736084	[1315,1479]	[1306,1154]	5	dCas9-KRAB	negative selection	5490884
169362445	169362468	2	+	27661255	K562	viability	GCGCGCGTAGCACACCGCACCGG	LRP2	ENSG00000081479	0.5207657406739818	[273,411]	[413,369]	9	dCas9-KRAB	negative selection	5490885
169362502	169362525	2	+	27661255	K562	viability	GCACCTCCGCCAGCTCCTAGTGG	LRP2	ENSG00000081479	-0.20282924803243008	[58,63]	[40,43]	-6	dCas9-KRAB	negative selection	5490886
169307301	169307324	2	-	27260156	BXPC3	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.07226885964149263	[392]	[420,432,392,484]	1	hSpCas9	negative selection	5553331
169320793	169320816	2	+	27260156	BXPC3	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.2825400264647173	[902]	[953,1010,1313,1365]	6	hSpCas9	negative selection	5553332
169320792	169320815	2	-	27260156	BXPC3	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.07106371984095639	[381]	[364,337,393,431]	-2	hSpCas9	negative selection	5553333
169307322	169307345	2	+	27260156	BXPC3	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	-0.12884605321834802	[591]	[428,514,624,730]	-3	hSpCas9	negative selection	5617590
169318864	169318887	2	-	27260156	BXPC3	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.2107273351635609	[759]	[766,926,1060,937]	4	hSpCas9	negative selection	5617591
169318828	169318851	2	+	27260156	BXPC3	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.007519951307308537	[976]	[982,936,1089,1111]	0	hSpCas9	negative selection	5617592
169307301	169307324	2	-	27260156	A673	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.073682877081825	[392]	[623,458,404,514]	1	hSpCas9	negative selection	5674582
169320793	169320816	2	+	27260156	A673	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.34732823566323323	[902]	[1367,1303,1429,1414]	7	hSpCas9	negative selection	5674583
169320792	169320815	2	-	27260156	A673	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.11404658270953999	[381]	[362,480,358,486]	-3	hSpCas9	negative selection	5674584
169307322	169307345	2	+	27260156	A673	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.10775549447400551	[591]	[760,732,805,761]	2	hSpCas9	negative selection	5738841
169318864	169318887	2	-	27260156	A673	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.13751402661747436	[759]	[1151,922,1025,926]	3	hSpCas9	negative selection	5738842
169318828	169318851	2	+	27260156	A673	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.10447330265958432	[976]	[1435,1132,1353,1134]	2	hSpCas9	negative selection	5738843
169307301	169307324	2	-	27260156	A375	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.11219047202011945	[392]	[443,674,390,496]	1	hSpCas9	negative selection	5795833
169320793	169320816	2	+	27260156	A375	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.6917200526408738	[902]	[1669,1797,1958,1426]	8	hSpCas9	negative selection	5795834
169320792	169320815	2	-	27260156	A375	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.10023810272625269	[381]	[333,740,543,343]	1	hSpCas9	negative selection	5795835
169307322	169307345	2	+	27260156	A375	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.15200903312517722	[591]	[856,1026,770,485]	2	hSpCas9	negative selection	5860092
169318864	169318887	2	-	27260156	A375	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.6138806045937104	[759]	[1225,1524,1472,1240]	8	hSpCas9	negative selection	5860093
169318828	169318851	2	+	27260156	A375	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.3232035830999873	[976]	[1597,1526,1470,1156]	5	hSpCas9	negative selection	5860094
169307301	169307324	2	-	27260156	COLO741	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.26333699156662277	[392]	[497,375,388]	-5	hSpCas9	negative selection	5917084
169320793	169320816	2	+	27260156	COLO741	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.3086150052321215	[902]	[1561,1335,1398]	6	hSpCas9	negative selection	5917085
169320792	169320815	2	-	27260156	COLO741	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.062265289979517746	[381]	[526,407,470]	-1	hSpCas9	negative selection	5917086
169307322	169307345	2	+	27260156	COLO741	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	-0.09162301061922007	[591]	[898,748,510]	-2	hSpCas9	negative selection	5981343
169318864	169318887	2	-	27260156	COLO741	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.2660260037812978	[759]	[1334,1160,1028]	5	hSpCas9	negative selection	5981344
169318828	169318851	2	+	27260156	COLO741	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.07074249000751287	[976]	[1255,1404,1267]	1	hSpCas9	negative selection	5981345
169307301	169307324	2	-	27260156	CAL120	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.07122552208870797	[392]	[807,462,317]	1	hSpCas9	negative selection	6038335
169320793	169320816	2	+	27260156	CAL120	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.3977344609617284	[902]	[1766,1199,1515]	6	hSpCas9	negative selection	6038336
169320792	169320815	2	-	27260156	CAL120	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.07855100476791782	[381]	[709,494,334]	1	hSpCas9	negative selection	6038337
169307322	169307345	2	+	27260156	CAL120	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.09311095257881447	[591]	[837,634,889]	1	hSpCas9	negative selection	6102594
169318864	169318887	2	-	27260156	CAL120	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.16059432767358994	[759]	[1398,1085,742]	2	hSpCas9	negative selection	6102595
169318828	169318851	2	+	27260156	CAL120	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.01974040878054617	[976]	[1421,1375,932]	0	hSpCas9	negative selection	6102596
169307301	169307324	2	-	27260156	CADOES1	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.14699035381781222	[392]	[380,254,331,352]	-3	hSpCas9	negative selection	6159586
169320793	169320816	2	+	27260156	CADOES1	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.5358979072722132	[902]	[1121,1401,1032,1317]	8	hSpCas9	negative selection	6159587
169320792	169320815	2	-	27260156	CADOES1	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.19686731820110392	[381]	[376,310,335,211]	-3	hSpCas9	negative selection	6159588
169307322	169307345	2	+	27260156	CADOES1	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.2804821146913644	[591]	[820,425,607,824]	5	hSpCas9	negative selection	6223845
169318864	169318887	2	-	27260156	CADOES1	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.24939895834584958	[759]	[890,842,883,738]	4	hSpCas9	negative selection	6223846
169318828	169318851	2	+	27260156	CADOES1	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.11889891439725098	[976]	[987,984,1060,909]	2	hSpCas9	negative selection	6223847
169307301	169307324	2	-	27260156	EWS502	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.2629659286725266	[392]	[350,375,342,311]	-4	hSpCas9	negative selection	6280837
169320793	169320816	2	+	27260156	EWS502	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.4887788010665737	[902]	[1231,1346,1248,1562]	8	hSpCas9	negative selection	6280838
169320792	169320815	2	-	27260156	EWS502	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.26827035107972075	[381]	[372,259,285,427]	-5	hSpCas9	negative selection	6280839
169307322	169307345	2	+	27260156	EWS502	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.18789660651237527	[591]	[885,632,523,796]	3	hSpCas9	negative selection	6345096
169318864	169318887	2	-	27260156	EWS502	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.34471952256635263	[759]	[1058,938,959,1132]	6	hSpCas9	negative selection	6345097
169318828	169318851	2	+	27260156	EWS502	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.27572847632253294	[976]	[1192,1317,1128,1377]	5	hSpCas9	negative selection	6345098
169307301	169307324	2	-	27260156	EW8	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.01930837446097733	[392]	[582,317,187,252]	0	hSpCas9	negative selection	6402088
169320793	169320816	2	+	27260156	EW8	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.37024027269973114	[902]	[1017,1011,714,1082]	6	hSpCas9	negative selection	6402089
169320792	169320815	2	-	27260156	EW8	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.20173205575790654	[381]	[415,261,350,400]	3	hSpCas9	negative selection	6402090
169307322	169307345	2	+	27260156	EW8	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.10406549668252424	[591]	[580,396,422,681]	2	hSpCas9	negative selection	6466347
169318864	169318887	2	-	27260156	EW8	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.41078776250015436	[759]	[835,852,680,927]	7	hSpCas9	negative selection	6466348
169318828	169318851	2	+	27260156	EW8	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.26009017497281617	[976]	[1204,771,891,957]	5	hSpCas9	negative selection	6466349
169307301	169307324	2	-	27260156	CORL105	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.04345273957117679	[392]	[231,339,677,565]	-1	hSpCas9	negative selection	6523339
169320793	169320816	2	+	27260156	CORL105	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.3581197646025551	[902]	[1447,1227,1723,1083]	6	hSpCas9	negative selection	6523340
169320792	169320815	2	-	27260156	CORL105	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.08757605674343028	[381]	[361,400,499,430]	-2	hSpCas9	negative selection	6523341
169307322	169307345	2	+	27260156	CORL105	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.19389360589632232	[591]	[813,471,1114,826]	3	hSpCas9	negative selection	6587598
169318864	169318887	2	-	27260156	CORL105	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	-0.009985651819345409	[759]	[934,798,962,852]	0	hSpCas9	negative selection	6587599
169318828	169318851	2	+	27260156	CORL105	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	-0.16071879738999784	[976]	[1118,922,1156,919]	-3	hSpCas9	negative selection	6587600
169307301	169307324	2	-	27260156	HS294T	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.12594849235121472	[392]	[134,225,99,209]	1	hSpCas9	negative selection	6644590
169320793	169320816	2	+	27260156	HS294T	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.6848745221482655	[902]	[645,533,483,573]	8	hSpCas9	negative selection	6644591
169320792	169320815	2	-	27260156	HS294T	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.5973996635381629	[381]	[148,304,232,207]	7	hSpCas9	negative selection	6644592
169307322	169307345	2	+	27260156	HS294T	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	-0.21374040954625534	[591]	[233,159,172,223]	-3	hSpCas9	negative selection	6708849
169318864	169318887	2	-	27260156	HS294T	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.6765413718930569	[759]	[450,376,374,720]	8	hSpCas9	negative selection	6708850
169318828	169318851	2	+	27260156	HS294T	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.12846187882285776	[976]	[368,431,274,610]	1	hSpCas9	negative selection	6708851
169307301	169307324	2	-	27260156	HCC44	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.429287682932595	[392]	[558,388,549,898]	7	hSpCas9	negative selection	6765841
169320793	169320816	2	+	27260156	HCC44	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.254414096778274	[902]	[1281,1143,1715,835]	4	hSpCas9	negative selection	6765842
169320792	169320815	2	-	27260156	HCC44	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.38645354210941063	[381]	[490,274,276,290]	-6	hSpCas9	negative selection	6765843
169307322	169307345	2	+	27260156	HCC44	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.3165211917622903	[591]	[1300,612,796,689]	5	hSpCas9	negative selection	6830100
169318864	169318887	2	-	27260156	HCC44	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.08889703107472957	[759]	[889,772,1202,852]	1	hSpCas9	negative selection	6830101
169318828	169318851	2	+	27260156	HCC44	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	-0.0018504023520096169	[976]	[1062,872,1379,1163]	0	hSpCas9	negative selection	6830102
169307301	169307324	2	-	27260156	G402	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.8921728112203946	[392]	[215,460,162,200]	-8	hSpCas9	negative selection	6887092
169320793	169320816	2	+	27260156	G402	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.7449087038861144	[902]	[2916,1797,1355,1477]	8	hSpCas9	negative selection	6887093
169320792	169320815	2	-	27260156	G402	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.9260409708836244	[381]	[194,258,298,221]	-8	hSpCas9	negative selection	6887094
169307322	169307345	2	+	27260156	G402	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.16364638669975118	[591]	[957,927,825,561]	2	hSpCas9	negative selection	6951351
169318864	169318887	2	-	27260156	G402	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.26618737884546906	[759]	[1336,1234,1005,926]	3	hSpCas9	negative selection	6951352
169318828	169318851	2	+	27260156	G402	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.2515569471441761	[976]	[1066,1488,1085,1955]	3	hSpCas9	negative selection	6951353
169307301	169307324	2	-	27260156	L33	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.0405939910179893	[392]	[338,181,295,364]	0	hSpCas9	negative selection	7008343
169320793	169320816	2	+	27260156	L33	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.4073274657102548	[902]	[1253,559,733,1001]	8	hSpCas9	negative selection	7008344
169320792	169320815	2	-	27260156	L33	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.13448002211482063	[381]	[492,183,202,409]	3	hSpCas9	negative selection	7008345
169307322	169307345	2	+	27260156	L33	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	-0.2345256372971229	[591]	[471,185,380,481]	-5	hSpCas9	negative selection	7072602
169318864	169318887	2	-	27260156	L33	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.23268085336363453	[759]	[927,410,572,729]	5	hSpCas9	negative selection	7072603
169318828	169318851	2	+	27260156	L33	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	-0.1629057993939269	[976]	[749,394,495,988]	-4	hSpCas9	negative selection	7072604
169307301	169307324	2	-	27260156	K562	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.5648059608359604	[392]	[285,385,167,126]	-6	hSpCas9	negative selection	7129594
169320793	169320816	2	+	27260156	K562	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.5222284280132958	[902]	[1169,797,1192,1391]	6	hSpCas9	negative selection	7129595
169320792	169320815	2	-	27260156	K562	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.6589302556316908	[381]	[209,236,199,211]	-6	hSpCas9	negative selection	7129596
169307322	169307345	2	+	27260156	K562	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.09271691723136571	[591]	[573,563,627,482]	1	hSpCas9	negative selection	7193853
169318864	169318887	2	-	27260156	K562	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.28356380274424553	[759]	[832,1037,660,766]	3	hSpCas9	negative selection	7193854
169318828	169318851	2	+	27260156	K562	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.14183387731303987	[976]	[976,933,636,1240]	1	hSpCas9	negative selection	7193855
169307301	169307324	2	-	27260156	HT29	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.14730800238289182	[392]	[403,504,533,299]	-3	hSpCas9	negative selection	7250845
169320793	169320816	2	+	27260156	HT29	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.3979704186095159	[902]	[1615,1567,1522,1130]	7	hSpCas9	negative selection	7250846
169320792	169320815	2	-	27260156	HT29	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.20220310234022532	[381]	[502,387,413,322]	-4	hSpCas9	negative selection	7250847
169307322	169307345	2	+	27260156	HT29	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.16982022970585497	[591]	[599,895,912,813]	3	hSpCas9	negative selection	7315104
169318864	169318887	2	-	27260156	HT29	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.20236925796354133	[759]	[1258,1130,1241,680]	4	hSpCas9	negative selection	7315105
169318828	169318851	2	+	27260156	HT29	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.04012165438931259	[976]	[1133,1672,1204,931]	0	hSpCas9	negative selection	7315106
169307301	169307324	2	-	27260156	MHHES1	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.1708482657379266	[392]	[402,384,519,282]	-3	hSpCas9	negative selection	7372096
169320793	169320816	2	+	27260156	MHHES1	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.4076440645375945	[902]	[1443,1515,1322,1155]	7	hSpCas9	negative selection	7372097
169320792	169320815	2	-	27260156	MHHES1	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.6371933750226381	[381]	[415,319,212,191]	-8	hSpCas9	negative selection	7372098
169307322	169307345	2	+	27260156	MHHES1	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.2531914720471088	[591]	[707,805,907,741]	4	hSpCas9	negative selection	7436355
169318864	169318887	2	-	27260156	MHHES1	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.1232670588357857	[759]	[960,1057,909,820]	2	hSpCas9	negative selection	7436356
169318828	169318851	2	+	27260156	MHHES1	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.21557948824336481	[976]	[1390,1272,1493,1002]	4	hSpCas9	negative selection	7436357
169307301	169307324	2	-	27260156	MEWO	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.521785694912505	[392]	[290,250,232]	-8	hSpCas9	negative selection	7493347
169320793	169320816	2	+	27260156	MEWO	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.24542680405358697	[902]	[1357,853,861]	5	hSpCas9	negative selection	7493348
169320792	169320815	2	-	27260156	MEWO	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.012893592809064214	[381]	[455,397,245]	0	hSpCas9	negative selection	7493349
169307322	169307345	2	+	27260156	MEWO	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	-0.22275947499840376	[591]	[529,362,541]	-5	hSpCas9	negative selection	7557606
169318864	169318887	2	-	27260156	MEWO	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	-0.10752032444638893	[759]	[822,521,666]	-2	hSpCas9	negative selection	7557607
169318828	169318851	2	+	27260156	MEWO	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.10625423417109126	[976]	[1000,943,1009]	2	hSpCas9	negative selection	7557608
169307301	169307324	2	-	27260156	LNCAPCLONEFGC	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.26505875217768016	[392]	[579,351,454,329]	4	hSpCas9	negative selection	7614598
169320793	169320816	2	+	27260156	LNCAPCLONEFGC	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.5413473955592083	[902]	[1095,1266,1043,1328]	8	hSpCas9	negative selection	7614599
169320792	169320815	2	-	27260156	LNCAPCLONEFGC	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.25973877013648494	[381]	[270,236,371,291]	-4	hSpCas9	negative selection	7614600
169307322	169307345	2	+	27260156	LNCAPCLONEFGC	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.22930823494030883	[591]	[644,595,668,611]	3	hSpCas9	negative selection	7678857
169318864	169318887	2	-	27260156	LNCAPCLONEFGC	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.32187959959352574	[759]	[861,733,1049,831]	5	hSpCas9	negative selection	7678858
169318828	169318851	2	+	27260156	LNCAPCLONEFGC	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.1563815694903985	[976]	[683,1070,1255,973]	2	hSpCas9	negative selection	7678859
169307301	169307324	2	-	27260156	PANC0327	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.08256770251886303	[392]	[396,185,478,280]	-1	hSpCas9	negative selection	7735849
169320793	169320816	2	+	27260156	PANC0327	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.34692227036745393	[902]	[1219,647,1118,1157]	5	hSpCas9	negative selection	7735850
169320792	169320815	2	-	27260156	PANC0327	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.36145550254524683	[381]	[173,256,301,316]	-5	hSpCas9	negative selection	7735851
169307322	169307345	2	+	27260156	PANC0327	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	-0.27202874486443235	[591]	[443,584,258,434]	-4	hSpCas9	negative selection	7800108
169318864	169318887	2	-	27260156	PANC0327	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.19304796150579817	[759]	[801,629,958,716]	3	hSpCas9	negative selection	7800109
169318828	169318851	2	+	27260156	PANC0327	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.21170734758971443	[976]	[946,801,1356,935]	3	hSpCas9	negative selection	7800110
169307301	169307324	2	-	27260156	NCIH2009	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.08646337818407257	[392]	[494,801,243]	-1	hSpCas9	negative selection	7857100
169320793	169320816	2	+	27260156	NCIH2009	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.5139690070848391	[902]	[2141,1523,1807]	7	hSpCas9	negative selection	7857101
169320792	169320815	2	-	27260156	NCIH2009	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.04669008372347638	[381]	[662,416,499]	0	hSpCas9	negative selection	7857102
169307322	169307345	2	+	27260156	NCIH2009	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.23439226116216694	[591]	[1187,968,802]	3	hSpCas9	negative selection	7921359
169318864	169318887	2	-	27260156	NCIH2009	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.26215503654325367	[759]	[1833,883,1217]	3	hSpCas9	negative selection	7921360
169318828	169318851	2	+	27260156	NCIH2009	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.1929647950692721	[976]	[1672,1379,1650]	2	hSpCas9	negative selection	7921361
169307301	169307324	2	-	27260156	NCIH1373	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.9261906727684046	[392]	[406,142,188,58]	-7	hSpCas9	negative selection	7978351
169320793	169320816	2	+	27260156	NCIH1373	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.93655858986516	[902]	[2700,1596,1423,577]	8	hSpCas9	negative selection	7978352
169320792	169320815	2	-	27260156	NCIH1373	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.23562666039837032	[381]	[357,467,338,70]	-2	hSpCas9	negative selection	7978353
169307322	169307345	2	+	27260156	NCIH1373	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.11629216531959108	[591]	[495,430,834,296]	1	hSpCas9	negative selection	8042610
169318864	169318887	2	-	27260156	NCIH1373	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.24535496626072162	[759]	[906,763,1430,243]	2	hSpCas9	negative selection	8042611
169318828	169318851	2	+	27260156	NCIH1373	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.12392207052071713	[976]	[1538,1049,988,332]	1	hSpCas9	negative selection	8042612
169307301	169307324	2	-	27260156	PATU8902	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.29938823052061586	[392]	[287,493,393,637]	-3	hSpCas9	negative selection	8099602
169320793	169320816	2	+	27260156	PATU8902	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.8124518181334737	[902]	[2834,1858,2096,2022]	8	hSpCas9	negative selection	8099603
169320792	169320815	2	-	27260156	PATU8902	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.2968467021726978	[381]	[448,565,405,298]	-3	hSpCas9	negative selection	8099604
169307322	169307345	2	+	27260156	PATU8902	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.06044165407778751	[591]	[1036,842,881,634]	0	hSpCas9	negative selection	8163861
169318864	169318887	2	-	27260156	PATU8902	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	-0.09100417108067471	[759]	[839,1448,677,1097]	-1	hSpCas9	negative selection	8163862
169318828	169318851	2	+	27260156	PATU8902	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.1553080397015547	[976]	[1654,1685,1029,1841]	1	hSpCas9	negative selection	8163863
169307301	169307324	2	-	27260156	PANC1	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.3103176166835048	[392]	[248,443,205,227]	-5	hSpCas9	negative selection	8220853
169320793	169320816	2	+	27260156	PANC1	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.5988364505480102	[902]	[1154,1627,1179,861]	8	hSpCas9	negative selection	8220854
169320792	169320815	2	-	27260156	PANC1	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.2650992252470089	[381]	[216,531,252,158]	-4	hSpCas9	negative selection	8220855
169307322	169307345	2	+	27260156	PANC1	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.1862440965191342	[591]	[756,596,445,513]	3	hSpCas9	negative selection	8285112
169318864	169318887	2	-	27260156	PANC1	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.16142553825027162	[759]	[691,706,772,731]	2	hSpCas9	negative selection	8285113
169318828	169318851	2	+	27260156	PANC1	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.0061651706345366986	[976]	[758,972,822,831]	0	hSpCas9	negative selection	8285114
169307301	169307324	2	-	27260156	PANC0813	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.17202587778654616	[392]	[589,361,570,560]	3	hSpCas9	negative selection	8342104
169320793	169320816	2	+	27260156	PANC0813	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.34420735774170264	[902]	[1314,1178,1147,1716]	5	hSpCas9	negative selection	8342105
169320792	169320815	2	-	27260156	PANC0813	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.358823560824465	[381]	[457,681,697,458]	6	hSpCas9	negative selection	8342106
169307322	169307345	2	+	27260156	PANC0813	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	-0.29843929321369567	[591]	[832,331,440,672]	-5	hSpCas9	negative selection	8406363
169318864	169318887	2	-	27260156	PANC0813	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.11894506541491545	[759]	[1099,1068,1003,728]	2	hSpCas9	negative selection	8406364
169318828	169318851	2	+	27260156	PANC0813	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	-0.08264791191752485	[976]	[1105,1165,1242,834]	-1	hSpCas9	negative selection	8406365
169307301	169307324	2	-	27260156	RDES	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.42624064518918653	[392]	[364,279,235,467]	-6	hSpCas9	negative selection	8463355
169320793	169320816	2	+	27260156	RDES	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.4269130945284103	[902]	[1295,1192,1413,1728]	6	hSpCas9	negative selection	8463356
169320792	169320815	2	-	27260156	RDES	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.6423323222798974	[381]	[313,229,249,324]	-8	hSpCas9	negative selection	8463357
169307322	169307345	2	+	27260156	RDES	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.28025441266752293	[591]	[582,705,844,1285]	4	hSpCas9	negative selection	8527614
169318864	169318887	2	-	27260156	RDES	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.3901382336520609	[759]	[964,1122,1178,1352]	6	hSpCas9	negative selection	8527615
169318828	169318851	2	+	27260156	RDES	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.15206899652698302	[976]	[1012,1199,1152,1712]	2	hSpCas9	negative selection	8527616
169307301	169307324	2	-	27260156	PC3	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.09971820526800201	[392]	[158,388,683,419]	-2	hSpCas9	negative selection	8584606
169320793	169320816	2	+	27260156	PC3	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.29188349300747896	[902]	[655,1166,2088,962]	6	hSpCas9	negative selection	8584607
169320792	169320815	2	-	27260156	PC3	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.04461539813809551	[381]	[304,496,337,393]	1	hSpCas9	negative selection	8584608
169307322	169307345	2	+	27260156	PC3	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.1775738606043581	[591]	[474,677,1027,637]	4	hSpCas9	negative selection	8648865
169318864	169318887	2	-	27260156	PC3	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.3422239231863491	[759]	[587,894,2001,832]	7	hSpCas9	negative selection	8648866
169318828	169318851	2	+	27260156	PC3	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.15741162306547474	[976]	[638,992,1926,1220]	3	hSpCas9	negative selection	8648867
169307301	169307324	2	-	27260156	PATU8988T	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.2475578584594539	[392]	[314,661,315,538]	4	hSpCas9	negative selection	8705857
169320793	169320816	2	+	27260156	PATU8988T	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.38956086480030594	[902]	[936,1639,890,1154]	6	hSpCas9	negative selection	8705858
169320792	169320815	2	-	27260156	PATU8988T	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.20446494311081884	[381]	[411,430,429,428]	3	hSpCas9	negative selection	8705859
169307322	169307345	2	+	27260156	PATU8988T	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.1888364413335677	[591]	[579,853,644,538]	3	hSpCas9	negative selection	8770116
169318864	169318887	2	-	27260156	PATU8988T	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.15824866544906835	[759]	[781,846,805,847]	2	hSpCas9	negative selection	8770117
169318828	169318851	2	+	27260156	PATU8988T	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.23204598869562143	[976]	[1147,979,822,1507]	4	hSpCas9	negative selection	8770118
169307301	169307324	2	-	27260156	T47D	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.06670062887565617	[392]	[461,453,468,536]	1	hSpCas9	negative selection	8827108
169320793	169320816	2	+	27260156	T47D	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.35967339949724897	[902]	[1436,1306,1382,1272]	7	hSpCas9	negative selection	8827109
169320792	169320815	2	-	27260156	T47D	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.018767769673229795	[381]	[453,396,486,469]	0	hSpCas9	negative selection	8827110
169307322	169307345	2	+	27260156	T47D	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.12221705421731499	[591]	[811,737,772,677]	2	hSpCas9	negative selection	8891367
169318864	169318887	2	-	27260156	T47D	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.21554985299675422	[759]	[1119,964,987,1045]	4	hSpCas9	negative selection	8891368
169318828	169318851	2	+	27260156	T47D	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	-0.04241037420068983	[976]	[1004,1050,1267,1097]	-1	hSpCas9	negative selection	8891369
169307301	169307324	2	-	27260156	SU8686	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.06670294093854517	[392]	[305,393,327,477]	-1	hSpCas9	negative selection	8948359
169320793	169320816	2	+	27260156	SU8686	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.49818154081108634	[902]	[1126,1096,1293,1627]	8	hSpCas9	negative selection	8948360
169320792	169320815	2	-	27260156	SU8686	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.17974762984062814	[381]	[372,307,583,482]	3	hSpCas9	negative selection	8948361
169307322	169307345	2	+	27260156	SU8686	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.22890456217114974	[591]	[576,576,660,1009]	4	hSpCas9	negative selection	9012618
169318864	169318887	2	-	27260156	SU8686	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.19741187332754584	[759]	[738,948,768,1017]	3	hSpCas9	negative selection	9012619
169318828	169318851	2	+	27260156	SU8686	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.10173163500383486	[976]	[1102,764,1214,1111]	1	hSpCas9	negative selection	9012620
169307301	169307324	2	-	27260156	SKES1	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.0633655844879189	[392]	[524,358,349,291]	-1	hSpCas9	negative selection	9069610
169320793	169320816	2	+	27260156	SKES1	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.2499442518744881	[902]	[1367,1102,923,940]	5	hSpCas9	negative selection	9069611
169320792	169320815	2	-	27260156	SKES1	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.039783831393808144	[381]	[585,360,296,275]	-1	hSpCas9	negative selection	9069612
169307322	169307345	2	+	27260156	SKES1	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.10118253770995123	[591]	[680,816,629,449]	2	hSpCas9	negative selection	9133869
169318864	169318887	2	-	27260156	SKES1	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.17087064175984612	[759]	[1149,983,732,623]	3	hSpCas9	negative selection	9133870
169318828	169318851	2	+	27260156	SKES1	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.025944273769801907	[976]	[1094,1054,981,863]	0	hSpCas9	negative selection	9133871
169307301	169307324	2	-	27260156	TOV112D	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.11584246530853995	[392]	[530,585,339,299]	2	hSpCas9	negative selection	9190861
169320793	169320816	2	+	27260156	TOV112D	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.1961923545177935	[902]	[1218,1107,959,892]	4	hSpCas9	negative selection	9190862
169320792	169320815	2	-	27260156	TOV112D	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.16841007157101928	[381]	[170,458,256,484]	-3	hSpCas9	negative selection	9190863
169307322	169307345	2	+	27260156	TOV112D	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	-0.11002106896914227	[591]	[492,611,578,523]	-2	hSpCas9	negative selection	9255120
169318864	169318887	2	-	27260156	TOV112D	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	-0.0404677023952108	[759]	[852,869,510,765]	-1	hSpCas9	negative selection	9255121
169318828	169318851	2	+	27260156	TOV112D	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.13202376898116297	[976]	[979,1476,1132,796]	2	hSpCas9	negative selection	9255122
169307301	169307324	2	-	27260156	TC71	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	0.0657670475396919	[392]	[369,538,346,516]	1	hSpCas9	negative selection	9312112
169320793	169320816	2	+	27260156	TC71	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.2471587805825468	[902]	[1028,1049,1222,1302]	6	hSpCas9	negative selection	9312113
169320792	169320815	2	-	27260156	TC71	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.20201732119247795	[381]	[485,317,587,488]	5	hSpCas9	negative selection	9312114
169307322	169307345	2	+	27260156	TC71	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.04656273447113157	[591]	[587,728,642,663]	1	hSpCas9	negative selection	9376371
169318864	169318887	2	-	27260156	TC71	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.11957385892100314	[759]	[885,831,910,911]	3	hSpCas9	negative selection	9376372
169318828	169318851	2	+	27260156	TC71	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	-0.12887410594865922	[976]	[876,982,983,989]	-3	hSpCas9	negative selection	9376373
169307301	169307324	2	-	27260156	TC32	viability	CACGTCAGAGACTGCCCCGATGG	LRP2	ENSG00000081479	-0.050199377672084045	[392]	[379,327,320,376]	-1	hSpCas9	negative selection	9433363
169320793	169320816	2	+	27260156	TC32	viability	CGCGTCATCTGAACAGTCTTTGG	LRP2	ENSG00000081479	0.6231482604257554	[902]	[1275,987,1585,1481]	9	hSpCas9	negative selection	9433364
169320792	169320815	2	-	27260156	TC32	viability	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.07601892583109757	[381]	[483,287,316,411]	1	hSpCas9	negative selection	9433365
169307322	169307345	2	+	27260156	TC32	viability	TGGTCGCACCTGTATTCACTTGG	LRP2	ENSG00000081479	0.2093583178677011	[591]	[759,494,795,542]	4	hSpCas9	negative selection	9497622
169318864	169318887	2	-	27260156	TC32	viability	AGCTGTTGTGACCTGCCAGCAGG	LRP2	ENSG00000081479	0.2793605285171036	[759]	[741,681,940,1165]	5	hSpCas9	negative selection	9497623
169318828	169318851	2	+	27260156	TC32	viability	GGATGCATTGTCCCTCACTCTGG	LRP2	ENSG00000081479	0.23972199844609854	[976]	[1015,945,1413,1005]	4	hSpCas9	negative selection	9497624
169280489	169280512	2	-	27869803	HPAFII	viability after 27 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	-1.8877265910722938	[214]	[11,45,NaN]	-8	hSpCas9	negative selection	9572224
169282916	169282939	2	-	27869803	HPAFII	viability after 27 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.7325074225195822	[362]	[345,292,NaN]	6	hSpCas9	negative selection	9572225
169289089	169289112	2	+	27869803	HPAFII	viability after 27 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	0.6357317992623369	[136]	[130,95,NaN]	5	hSpCas9	negative selection	9572226
169294189	169294212	2	+	27869803	HPAFII	viability after 27 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.1321679118597861	[306]	[71,209,NaN]	-1	hSpCas9	negative selection	9572227
169320792	169320815	2	-	27869803	HPAFII	viability after 27 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.9180338008682526	[428]	[138,102,NaN]	-6	hSpCas9	negative selection	9572228
169362310	169362333	2	+	27869803	HPAFII	viability after 27 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-0.8736396815097989	[127]	[33,38,NaN]	-6	hSpCas9	negative selection	9572229
169280489	169280512	2	-	27869803	HPAFII	viability after 15 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	-0.961918971888825	[214]	[191,72,NaN]	-7	hSpCas9	negative selection	9654673
169282916	169282939	2	-	27869803	HPAFII	viability after 15 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	-0.11578408623038838	[362]	[610,203,NaN]	-1	hSpCas9	negative selection	9654674
169289089	169289112	2	+	27869803	HPAFII	viability after 15 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	0.28523713650486127	[136]	[274,119,NaN]	3	hSpCas9	negative selection	9654675
169294189	169294212	2	+	27869803	HPAFII	viability after 15 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.6570157700754393	[306]	[162,237,NaN]	-6	hSpCas9	negative selection	9654676
169320792	169320815	2	-	27869803	HPAFII	viability after 15 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.0861825092235251	[428]	[503,390,NaN]	-1	hSpCas9	negative selection	9654677
169362310	169362333	2	+	27869803	HPAFII	viability after 15 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-0.21975521439280032	[127]	[246,37,NaN]	-3	hSpCas9	negative selection	9654678
169280489	169280512	2	-	27869803	ASPC1	viability after 36 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	0.5941837197518488	[279]	[85,143,191]	6	hSpCas9	negative selection	9737122
169282916	169282939	2	-	27869803	ASPC1	viability after 36 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.15278466630910548	[938]	[347,691,111]	1	hSpCas9	negative selection	9737123
169289089	169289112	2	+	27869803	ASPC1	viability after 36 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	0.3815257192989868	[397]	[167,247,134]	4	hSpCas9	negative selection	9737124
169294189	169294212	2	+	27869803	ASPC1	viability after 36 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-1.6381624605741116	[526]	[3,23,124]	-9	hSpCas9	negative selection	9737125
169320792	169320815	2	-	27869803	ASPC1	viability after 36 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.7072880903563363	[1175]	[1252,802,148]	7	hSpCas9	negative selection	9737126
169362310	169362333	2	+	27869803	ASPC1	viability after 36 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	0.5111502506498709	[189]	[16,169,87]	5	hSpCas9	negative selection	9737127
169280489	169280512	2	-	27869803	PATU8988S	viability after 35 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	-0.2506110596884932	[364]	[150,95,NaN]	-3	hSpCas9	negative selection	9819571
169282916	169282939	2	-	27869803	PATU8988S	viability after 35 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.34406778046540243	[793]	[366,444,NaN]	4	hSpCas9	negative selection	9819572
169289089	169289112	2	+	27869803	PATU8988S	viability after 35 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	-0.022716348284354343	[486]	[225,159,NaN]	0	hSpCas9	negative selection	9819573
169294189	169294212	2	+	27869803	PATU8988S	viability after 35 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	0.8311891016497097	[417]	[307,290,NaN]	8	hSpCas9	negative selection	9819574
169320792	169320815	2	-	27869803	PATU8988S	viability after 35 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.5865228077631816	[997]	[633,572,NaN]	6	hSpCas9	negative selection	9819575
169362310	169362333	2	+	27869803	PATU8988S	viability after 35 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	1.642778336798272	[271]	[158,525,NaN]	9	hSpCas9	negative selection	9819576
169280489	169280512	2	-	27869803	PATU8988S	viability after 31 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	-0.17842670392125337	[364]	[176,66,NaN]	-2	hSpCas9	negative selection	9902020
169282916	169282939	2	-	27869803	PATU8988S	viability after 31 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.27520205575382317	[793]	[288,502,NaN]	3	hSpCas9	negative selection	9902021
169289089	169289112	2	+	27869803	PATU8988S	viability after 31 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	-0.07714444015771615	[486]	[169,201,NaN]	-1	hSpCas9	negative selection	9902022
169294189	169294212	2	+	27869803	PATU8988S	viability after 31 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	0.8918198257971544	[417]	[248,385,NaN]	8	hSpCas9	negative selection	9902023
169320792	169320815	2	-	27869803	PATU8988S	viability after 31 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	0.1977949774557507	[997]	[367,568,NaN]	2	hSpCas9	negative selection	9902024
169362310	169362333	2	+	27869803	PATU8988S	viability after 31 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	1.2209631135984889	[271]	[148,384,NaN]	9	hSpCas9	negative selection	9902025
169280489	169280512	2	-	27869803	HPAFII	viability after 35 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	-1.6568362464431734	[214]	[10,60,NaN]	-7	hSpCas9	negative selection	9984469
169282916	169282939	2	-	27869803	HPAFII	viability after 35 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.09442660784226953	[362]	[119,281,NaN]	0	hSpCas9	negative selection	9984470
169289089	169289112	2	+	27869803	HPAFII	viability after 35 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	0.5572642755363917	[136]	[94,109,NaN]	3	hSpCas9	negative selection	9984471
169294189	169294212	2	+	27869803	HPAFII	viability after 35 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.3974598962821169	[306]	[101,135,NaN]	-2	hSpCas9	negative selection	9984472
169320792	169320815	2	-	27869803	HPAFII	viability after 35 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.5546796446655242	[428]	[216,69,NaN]	-3	hSpCas9	negative selection	9984473
169362310	169362333	2	+	27869803	HPAFII	viability after 35 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-0.7438118772065776	[127]	[17,61,NaN]	-4	hSpCas9	negative selection	9984474
169280489	169280512	2	-	27869803	HPAFII	viability after 31 days	GCCTCCATTATCTTCTCCAATGG	LRP2	ENSG00000081479	-1.689579777409818	[214]	[12,63,NaN]	-7	hSpCas9	negative selection	10066918
169282916	169282939	2	-	27869803	HPAFII	viability after 31 days	ACCTGTGCCACTGTGAAGAAGGG	LRP2	ENSG00000081479	0.4686582382910991	[362]	[212,356,NaN]	3	hSpCas9	negative selection	10066919
169289089	169289112	2	+	27869803	HPAFII	viability after 31 days	CATACGGCGTCTCATGGCACTGG	LRP2	ENSG00000081479	0.18336690145940193	[136]	[82,91,NaN]	1	hSpCas9	negative selection	10066920
169294189	169294212	2	+	27869803	HPAFII	viability after 31 days	TGGTCACAGACATAAGCACGAGG	LRP2	ENSG00000081479	-0.3331759183121426	[306]	[164,105,NaN]	-2	hSpCas9	negative selection	10066921
169320792	169320815	2	-	27869803	HPAFII	viability after 31 days	CAAAGACTGTTCAGATGACGCGG	LRP2	ENSG00000081479	-0.13057140783707466	[428]	[262,172,NaN]	-1	hSpCas9	negative selection	10066922
169362310	169362333	2	+	27869803	HPAFII	viability after 31 days	TGGGCTCTTACCTTGGCCACTGG	LRP2	ENSG00000081479	-1.2909891387006636	[127]	[14,44,NaN]	-7	hSpCas9	negative selection	10066923
169279385	169279408	2	-	28162770	P31FUJ	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	-0.6478397036932224	[159]	[119]	-5	hSpCas9	negative selection	10185812
169275218	169275241	2	-	28162770	P31FUJ	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	0.2989589011661479	[266]	[385]	3	hSpCas9	negative selection	10185813
169191964	169191987	2	+	28162770	P31FUJ	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	0.16983027397368455	[291]	[385]	1	hSpCas9	negative selection	10185814
169320776	169320799	2	-	28162770	P31FUJ	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	-0.43378926214755587	[222]	[193]	-4	hSpCas9	negative selection	10185815
169292351	169292374	2	-	28162770	P31FUJ	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	-0.14050535709359635	[332]	[354]	-1	hSpCas9	negative selection	10185816
169292338	169292361	2	+	28162770	P31FUJ	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	0.8291718168407276	[261]	[546]	8	hSpCas9	negative selection	10185817
169290886	169290909	2	-	28162770	P31FUJ	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	1.0799073604436051	[156]	[389]	9	hSpCas9	negative selection	10185818
169289048	169289071	2	+	28162770	P31FUJ	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	-0.28489071556283274	[140]	[135]	-3	hSpCas9	negative selection	10185819
169280415	169280438	2	-	28162770	P31FUJ	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	0.4142212644390291	[181]	[284]	4	hSpCas9	negative selection	10185820
169280392	169280415	2	+	28162770	P31FUJ	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.15862273764251444	[615]	[807]	1	hSpCas9	negative selection	10185821
169279385	169279408	2	-	28162770	TF1	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10355178
169275218	169275241	2	-	28162770	TF1	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	NaN	[NaN]	[271]	1	hSpCas9	negative selection	10355179
169191964	169191987	2	+	28162770	TF1	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	NaN	[NaN]	[86]	1	hSpCas9	negative selection	10355180
169320776	169320799	2	-	28162770	TF1	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	NaN	[NaN]	[111]	1	hSpCas9	negative selection	10355181
169292351	169292374	2	-	28162770	TF1	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	NaN	[NaN]	[276]	1	hSpCas9	negative selection	10355182
169292338	169292361	2	+	28162770	TF1	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	NaN	[NaN]	[126]	1	hSpCas9	negative selection	10355183
169290886	169290909	2	-	28162770	TF1	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10355184
169289048	169289071	2	+	28162770	TF1	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	NaN	[NaN]	[84]	1	hSpCas9	negative selection	10355185
169280415	169280438	2	-	28162770	TF1	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10355186
169280392	169280415	2	+	28162770	TF1	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	NaN	[NaN]	[678]	1	hSpCas9	negative selection	10355187
169279385	169279408	2	-	28162770	SKM1	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	-0.7362718239961215	[48]	[51]	-5	hSpCas9	negative selection	10524544
169275218	169275241	2	-	28162770	SKM1	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	-0.4434900747682757	[59]	[77]	-4	hSpCas9	negative selection	10524545
169191964	169191987	2	+	28162770	SKM1	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	0.24556158579062898	[72]	[152]	2	hSpCas9	negative selection	10524546
169320776	169320799	2	-	28162770	SKM1	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	0.25496028379287866	[72]	[153]	2	hSpCas9	negative selection	10524547
169292351	169292374	2	-	28162770	SKM1	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	0.22530401675635114	[89]	[185]	2	hSpCas9	negative selection	10524548
169292338	169292361	2	+	28162770	SKM1	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	0.4343380552377799	[89]	[214]	4	hSpCas9	negative selection	10524549
169290886	169290909	2	-	28162770	SKM1	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	0.1499839258083978	[51]	[101]	1	hSpCas9	negative selection	10524550
169289048	169289071	2	+	28162770	SKM1	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	-0.41600933834616866	[39]	[52]	-3	hSpCas9	negative selection	10524551
169280415	169280438	2	-	28162770	SKM1	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	0.16151017918942553	[43]	[86]	1	hSpCas9	negative selection	10524552
169280392	169280415	2	+	28162770	SKM1	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	1.4378654287331054	[94]	[454]	9	hSpCas9	negative selection	10524553
169279385	169279408	2	-	28162770	SKM1	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	-0.7362718239961215	[48]	[51]	-5	hSpCas9	negative selection	10693910
169275218	169275241	2	-	28162770	SKM1	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	-0.4434900747682757	[59]	[77]	-4	hSpCas9	negative selection	10693911
169191964	169191987	2	+	28162770	SKM1	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	0.24556158579062898	[72]	[152]	2	hSpCas9	negative selection	10693912
169320776	169320799	2	-	28162770	SKM1	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	0.25496028379287866	[72]	[153]	2	hSpCas9	negative selection	10693913
169292351	169292374	2	-	28162770	SKM1	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	0.22530401675635114	[89]	[185]	2	hSpCas9	negative selection	10693914
169292338	169292361	2	+	28162770	SKM1	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	0.4343380552377799	[89]	[214]	4	hSpCas9	negative selection	10693915
169290886	169290909	2	-	28162770	SKM1	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	0.1499839258083978	[51]	[101]	1	hSpCas9	negative selection	10693916
169289048	169289071	2	+	28162770	SKM1	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	-0.41600933834616866	[39]	[52]	-3	hSpCas9	negative selection	10693917
169280415	169280438	2	-	28162770	SKM1	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	0.16151017918942553	[43]	[86]	1	hSpCas9	negative selection	10693918
169280392	169280415	2	+	28162770	SKM1	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	1.4378654287331054	[94]	[454]	9	hSpCas9	negative selection	10693919
169279385	169279408	2	-	28162770	PL21	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	1.2701021726568875	[160]	[168]	9	hSpCas9	negative selection	10863276
169275218	169275241	2	-	28162770	PL21	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	-0.14778368893098687	[195]	[76]	-1	hSpCas9	negative selection	10863277
169191964	169191987	2	+	28162770	PL21	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	-0.8090789155400585	[313]	[77]	-5	hSpCas9	negative selection	10863278
169320776	169320799	2	-	28162770	PL21	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	0.027824065622013783	[150]	[66]	0	hSpCas9	negative selection	10863279
169292351	169292374	2	-	28162770	PL21	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	-0.4431215267965033	[302]	[96]	-3	hSpCas9	negative selection	10863280
169292338	169292361	2	+	28162770	PL21	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	-0.03958741785240483	[306]	[129]	0	hSpCas9	negative selection	10863281
169290886	169290909	2	-	28162770	PL21	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	0.7680286018515348	[169]	[125]	6	hSpCas9	negative selection	10863282
169289048	169289071	2	+	28162770	PL21	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	-0.2901860120937607	[117]	[41]	-2	hSpCas9	negative selection	10863283
169280415	169280438	2	-	28162770	PL21	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	-0.1624304648953881	[161]	[62]	-1	hSpCas9	negative selection	10863284
169280392	169280415	2	+	28162770	PL21	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.19620319993014967	[366]	[182]	1	hSpCas9	negative selection	10863285
169279385	169279408	2	-	28162770	P31FUJ	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	-0.6478397036932224	[159]	[119]	-5	hSpCas9	negative selection	11032642
169275218	169275241	2	-	28162770	P31FUJ	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	0.2989589011661479	[266]	[385]	3	hSpCas9	negative selection	11032643
169191964	169191987	2	+	28162770	P31FUJ	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	0.16983027397368455	[291]	[385]	1	hSpCas9	negative selection	11032644
169320776	169320799	2	-	28162770	P31FUJ	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	-0.43378926214755587	[222]	[193]	-4	hSpCas9	negative selection	11032645
169292351	169292374	2	-	28162770	P31FUJ	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	-0.14050535709359635	[332]	[354]	-1	hSpCas9	negative selection	11032646
169292338	169292361	2	+	28162770	P31FUJ	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	0.8291718168407276	[261]	[546]	8	hSpCas9	negative selection	11032647
169290886	169290909	2	-	28162770	P31FUJ	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	1.0799073604436051	[156]	[389]	9	hSpCas9	negative selection	11032648
169289048	169289071	2	+	28162770	P31FUJ	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	-0.28489071556283274	[140]	[135]	-3	hSpCas9	negative selection	11032649
169280415	169280438	2	-	28162770	P31FUJ	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	0.4142212644390291	[181]	[284]	4	hSpCas9	negative selection	11032650
169280392	169280415	2	+	28162770	P31FUJ	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.15862273764251444	[615]	[807]	1	hSpCas9	negative selection	11032651
169279385	169279408	2	-	28162770	OCIAML5	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	0.6661698160563461	[58]	[168]	6	hSpCas9	negative selection	11202008
169275218	169275241	2	-	28162770	OCIAML5	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	0.09546600924186745	[125]	[242]	0	hSpCas9	negative selection	11202009
169191964	169191987	2	+	28162770	OCIAML5	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	-0.46714905996148837	[120]	[157]	-3	hSpCas9	negative selection	11202010
169320776	169320799	2	-	28162770	OCIAML5	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	0.9002742491891251	[83]	[282]	7	hSpCas9	negative selection	11202011
169292351	169292374	2	-	28162770	OCIAML5	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	0.02928893263738419	[170]	[314]	0	hSpCas9	negative selection	11202012
169292338	169292361	2	+	28162770	OCIAML5	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	-0.4672072202501779	[156]	[204]	-3	hSpCas9	negative selection	11202013
169290886	169290909	2	-	28162770	OCIAML5	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	-0.6893370708258887	[133]	[149]	-4	hSpCas9	negative selection	11202014
169289048	169289071	2	+	28162770	OCIAML5	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	0.022402547052144117	[89]	[164]	0	hSpCas9	negative selection	11202015
169280415	169280438	2	-	28162770	OCIAML5	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	0.6869881234005664	[148]	[432]	6	hSpCas9	negative selection	11202016
169280392	169280415	2	+	28162770	OCIAML5	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.4046773552632279	[248]	[594]	3	hSpCas9	negative selection	11202017
169279385	169279408	2	-	28162770	EOL1	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	-1.1519937833024585	[328]	[77]	-6	hSpCas9	negative selection	11371374
169275218	169275241	2	-	28162770	EOL1	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	-0.7344153105943985	[239]	[75]	-5	hSpCas9	negative selection	11371375
169191964	169191987	2	+	28162770	EOL1	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	0.17023084289320156	[473]	[280]	1	hSpCas9	negative selection	11371376
169320776	169320799	2	-	28162770	EOL1	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	0.9853729642665778	[417]	[435]	8	hSpCas9	negative selection	11371377
169292351	169292374	2	-	28162770	EOL1	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	1.0972077407340857	[526]	[593]	8	hSpCas9	negative selection	11371378
169292338	169292361	2	+	28162770	EOL1	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	-0.31781306599850934	[581]	[245]	-2	hSpCas9	negative selection	11371379
169290886	169290909	2	-	28162770	EOL1	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	0.6699749444849368	[203]	[170]	6	hSpCas9	negative selection	11371380
169289048	169289071	2	+	28162770	EOL1	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	-0.49359563857613087	[154]	[57]	-4	hSpCas9	negative selection	11371381
169280415	169280438	2	-	28162770	EOL1	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	0.7725446781254844	[199]	[179]	6	hSpCas9	negative selection	11371382
169280392	169280415	2	+	28162770	EOL1	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.4132655025547701	[562]	[394]	4	hSpCas9	negative selection	11371383
169279385	169279408	2	-	28162770	MOLM13	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	-0.4612271322989113	[277]	[145]	-3	hSpCas9	negative selection	11540740
169275218	169275241	2	-	28162770	MOLM13	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	0.970389722073762	[299]	[424]	7	hSpCas9	negative selection	11540741
169191964	169191987	2	+	28162770	MOLM13	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	0.11641701104320112	[406]	[318]	0	hSpCas9	negative selection	11540742
169320776	169320799	2	-	28162770	MOLM13	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	1.0081732918345094	[316]	[460]	7	hSpCas9	negative selection	11540743
169292351	169292374	2	-	28162770	MOLM13	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	0.4042307443222609	[416]	[398]	3	hSpCas9	negative selection	11540744
169292338	169292361	2	+	28162770	MOLM13	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	0.8966400484796043	[444]	[598]	6	hSpCas9	negative selection	11540745
169290886	169290909	2	-	28162770	MOLM13	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	-0.25339459038935763	[243]	[147]	-1	hSpCas9	negative selection	11540746
169289048	169289071	2	+	28162770	MOLM13	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	-0.2918475202802854	[148]	[87]	-2	hSpCas9	negative selection	11540747
169280415	169280438	2	-	28162770	MOLM13	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	0.00023725610231309369	[241]	[174]	0	hSpCas9	negative selection	11540748
169280392	169280415	2	+	28162770	MOLM13	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.6236107632357389	[464]	[517]	5	hSpCas9	negative selection	11540749
169279385	169279408	2	-	28162770	HEL	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	0.7075090873905947	[195]	[204]	6	hSpCas9	negative selection	11710106
169275218	169275241	2	-	28162770	HEL	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	0.5086021593488206	[213]	[194]	4	hSpCas9	negative selection	11710107
169191964	169191987	2	+	28162770	HEL	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	0.4858699833834911	[329]	[295]	4	hSpCas9	negative selection	11710108
169320776	169320799	2	-	28162770	HEL	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	0.2063276819289462	[271]	[200]	1	hSpCas9	negative selection	11710109
169292351	169292374	2	-	28162770	HEL	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	0.6208793980366177	[398]	[392]	5	hSpCas9	negative selection	11710110
169292338	169292361	2	+	28162770	HEL	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	1.4097194061518454	[351]	[598]	9	hSpCas9	negative selection	11710111
169290886	169290909	2	-	28162770	HEL	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	-0.06775455080465803	[179]	[109]	0	hSpCas9	negative selection	11710112
169289048	169289071	2	+	28162770	HEL	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	0.7640451282224906	[113]	[123]	6	hSpCas9	negative selection	11710113
169280415	169280438	2	-	28162770	HEL	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	1.2754770572909266	[197]	[306]	9	hSpCas9	negative selection	11710114
169280392	169280415	2	+	28162770	HEL	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.5233236650555861	[427]	[393]	4	hSpCas9	negative selection	11710115
169279385	169279408	2	-	28162770	MV411	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	0.8764552315818668	[171]	[265]	7	hSpCas9	negative selection	11879472
169275218	169275241	2	-	28162770	MV411	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	-1.3855049788402025	[213]	[68]	-7	hSpCas9	negative selection	11879473
169191964	169191987	2	+	28162770	MV411	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	-0.3401220614244199	[277]	[184]	-3	hSpCas9	negative selection	11879474
169320776	169320799	2	-	28162770	MV411	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	0.6489918206979971	[214]	[283]	6	hSpCas9	negative selection	11879475
169292351	169292374	2	-	28162770	MV411	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	0.47354538761821185	[276]	[323]	4	hSpCas9	negative selection	11879476
169292338	169292361	2	+	28162770	MV411	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	0.027216228487954464	[331]	[284]	0	hSpCas9	negative selection	11879477
169290886	169290909	2	-	28162770	MV411	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	-0.49558979617063215	[158]	[94]	-4	hSpCas9	negative selection	11879478
169289048	169289071	2	+	28162770	MV411	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	-1.0795437718308722	[142]	[56]	-6	hSpCas9	negative selection	11879479
169280415	169280438	2	-	28162770	MV411	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	0.907254046188145	[168]	[266]	7	hSpCas9	negative selection	11879480
169280392	169280415	2	+	28162770	MV411	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.7503916403457003	[373]	[529]	6	hSpCas9	negative selection	11879481
169279385	169279408	2	-	28162770	MONOMAC1	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	0.3563555746607328	[76]	[112]	3	hSpCas9	negative selection	12048838
169275218	169275241	2	-	28162770	MONOMAC1	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	-0.46739459369920644	[157]	[130]	-4	hSpCas9	negative selection	12048839
169191964	169191987	2	+	28162770	MONOMAC1	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	0.6039297470355032	[193]	[337]	6	hSpCas9	negative selection	12048840
169320776	169320799	2	-	28162770	MONOMAC1	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	0.06599755877424025	[129]	[155]	0	hSpCas9	negative selection	12048841
169292351	169292374	2	-	28162770	MONOMAC1	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	0.3334778696392263	[233]	[337]	3	hSpCas9	negative selection	12048842
169292338	169292361	2	+	28162770	MONOMAC1	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	0.6724611287063186	[184]	[337]	6	hSpCas9	negative selection	12048843
169290886	169290909	2	-	28162770	MONOMAC1	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	0.7886078599633763	[100]	[199]	7	hSpCas9	negative selection	12048844
169289048	169289071	2	+	28162770	MONOMAC1	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	0.945257035405568	[81]	[180]	8	hSpCas9	negative selection	12048845
169280415	169280438	2	-	28162770	MONOMAC1	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	0.023353221365746496	[102]	[119]	0	hSpCas9	negative selection	12048846
169280392	169280415	2	+	28162770	MONOMAC1	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.10096123102907073	[230]	[283]	1	hSpCas9	negative selection	12048847
169279385	169279408	2	-	28162770	OCIAML2	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	0.2718739524654749	[25]	[173]	2	hSpCas9	negative selection	12218204
169275218	169275241	2	-	28162770	OCIAML2	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	1.0529321308148518	[21]	[252]	8	hSpCas9	negative selection	12218205
169191964	169191987	2	+	28162770	OCIAML2	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	0.02290964771540016	[56]	[320]	0	hSpCas9	negative selection	12218206
169320776	169320799	2	-	28162770	OCIAML2	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	0.07369069098164893	[53]	[314]	0	hSpCas9	negative selection	12218207
169292351	169292374	2	-	28162770	OCIAML2	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	-0.09117802923382312	[58]	[306]	0	hSpCas9	negative selection	12218208
169292338	169292361	2	+	28162770	OCIAML2	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	0.41811342365609805	[63]	[473]	4	hSpCas9	negative selection	12218209
169290886	169290909	2	-	28162770	OCIAML2	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	-0.10886146582300787	[49]	[256]	-1	hSpCas9	negative selection	12218210
169289048	169289071	2	+	28162770	OCIAML2	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	0.09415479354136458	[23]	[141]	0	hSpCas9	negative selection	12218211
169280415	169280438	2	-	28162770	OCIAML2	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	0.5919821520575175	[30]	[258]	6	hSpCas9	negative selection	12218212
169280392	169280415	2	+	28162770	OCIAML2	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.4574772562760534	[71]	[547]	4	hSpCas9	negative selection	12218213
169279385	169279408	2	-	28162770	OCIAML3	viability	GCATCCTAGAGGAATTGCCGTGG	LRP2	ENSG00000081479	0.2369341020510568	[51]	[184]	2	hSpCas9	negative selection	12387570
169275218	169275241	2	-	28162770	OCIAML3	viability	AGGAAGACTGTAGTTCATGGAGG	LRP2	ENSG00000081479	-0.38519362548825586	[60]	[140]	-3	hSpCas9	negative selection	12387571
169191964	169191987	2	+	28162770	OCIAML3	viability	GGAATGCACCTCCTGTCCGGAGG	LRP2	ENSG00000081479	0.1409803044016007	[72]	[242]	1	hSpCas9	negative selection	12387572
169320776	169320799	2	-	28162770	OCIAML3	viability	GACGCGGATGAAATTGGCTGCGG	LRP2	ENSG00000081479	-0.7272741711876273	[67]	[123]	-5	hSpCas9	negative selection	12387573
169292351	169292374	2	-	28162770	OCIAML3	viability	CCAGACTATCCGACCTGCGGTGG	LRP2	ENSG00000081479	0.0996215457000359	[97]	[316]	0	hSpCas9	negative selection	12387574
169292338	169292361	2	+	28162770	OCIAML3	viability	AGTGAACTGGTAACCACCGCAGG	LRP2	ENSG00000081479	0.11321061044799097	[97]	[319]	1	hSpCas9	negative selection	12387575
169290886	169290909	2	-	28162770	OCIAML3	viability	GATGGGATTTTAGATTGCCCAGG	LRP2	ENSG00000081479	-0.026018218206720622	[56]	[168]	0	hSpCas9	negative selection	12387576
169289048	169289071	2	+	28162770	OCIAML3	viability	GTGGTTGATGATATAACCTGGGG	LRP2	ENSG00000081479	-0.2577242524597309	[39]	[100]	-2	hSpCas9	negative selection	12387577
169280415	169280438	2	-	28162770	OCIAML3	viability	GGAGTCTCAGAATCGTGGAGTGG	LRP2	ENSG00000081479	-0.2482328034824332	[47]	[121]	-2	hSpCas9	negative selection	12387578
169280392	169280415	2	+	28162770	OCIAML3	viability	ATAGTGGAAAGCCACACCCACGG	LRP2	ENSG00000081479	0.27459447055998143	[111]	[408]	2	hSpCas9	negative selection	12387579