Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5604
• Symbol: MAP2K1
• Description: mitogen-activated protein kinase kinase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/MAP2K1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
66435039	66435062	15	+	26472758	Jiyoye	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-1.6482377388127332	[344]	[82]	-8	hSpCas9	negative selection	95876
66481763	66481786	15	-	26472758	Jiyoye	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-1.1598652112180203	[239]	[80]	-7	hSpCas9	negative selection	95877
66435117	66435140	15	+	26472758	Jiyoye	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	0.6999571307337192	[119]	[146]	5	hSpCas9	negative selection	95878
66444686	66444709	15	+	26472758	Jiyoye	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	0.853161469078219	[195]	[266]	6	hSpCas9	negative selection	95879
66481851	66481874	15	-	26472758	Jiyoye	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	0.18292740359094362	[388]	[332]	1	hSpCas9	negative selection	95880
66485046	66485069	15	+	26472758	Jiyoye	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	0.4685759261700166	[160]	[167]	3	hSpCas9	negative selection	95881
66435078	66435101	15	+	26472758	Jiyoye	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	0.9546631768083665	[38]	[56]	6	hSpCas9	negative selection	95882
66436842	66436865	15	+	26472758	Jiyoye	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	1.128874219018769	[170]	[281]	7	hSpCas9	negative selection	95883
66487235	66487258	15	+	26472758	Jiyoye	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	-0.15043663107032734	[417]	[283]	-1	hSpCas9	negative selection	95884
66435105	66435128	15	+	26472758	Jiyoye	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	0.4071753815058734	[23]	[23]	3	hSpCas9	negative selection	95885
66435039	66435062	15	+	26472758	KBM7	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-0.6498482389624104	[882,633]	[439,31]	-5	hSpCas9	negative selection	286994
66481763	66481786	15	-	26472758	KBM7	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	0.13497626599230075	[554,542]	[255,309]	1	hSpCas9	negative selection	286995
66435117	66435140	15	+	26472758	KBM7	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-0.99035210634943	[656,503]	[188,88]	-6	hSpCas9	negative selection	286996
66444686	66444709	15	+	26472758	KBM7	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	0.0280668845587011	[827,705]	[403,332]	0	hSpCas9	negative selection	286997
66481851	66481874	15	-	26472758	KBM7	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	0.03862856833644113	[1652,1478]	[657,842]	0	hSpCas9	negative selection	286998
66485046	66485069	15	+	26472758	KBM7	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	-0.6136576049712655	[926,834]	[334,212]	-5	hSpCas9	negative selection	286999
66435078	66435101	15	+	26472758	KBM7	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	0.15482938321083198	[429,305]	[194,185]	1	hSpCas9	negative selection	287000
66436842	66436865	15	+	26472758	KBM7	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.7772905179969157	[1127,1496]	[385,349]	-6	hSpCas9	negative selection	287001
66487235	66487258	15	+	26472758	KBM7	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	-0.08968726589746656	[1732,1191]	[615,655]	-1	hSpCas9	negative selection	287002
66435105	66435128	15	+	26472758	KBM7	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-0.1287396758246908	[283,191]	[122,80]	-1	hSpCas9	negative selection	287003
66435039	66435062	15	+	26472758	Raji	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-2.5460587032303232	[452]	[17]	-9	hSpCas9	negative selection	478112
66481763	66481786	15	-	26472758	Raji	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	0.06473919796510569	[205]	[49]	0	hSpCas9	negative selection	478113
66435117	66435140	15	+	26472758	Raji	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-0.35204808326369796	[252]	[45]	-3	hSpCas9	negative selection	478114
66444686	66444709	15	+	26472758	Raji	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	0.11184318356429923	[322]	[80]	1	hSpCas9	negative selection	478115
66481851	66481874	15	-	26472758	Raji	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	-0.16357778623182306	[583]	[120]	-1	hSpCas9	negative selection	478116
66485046	66485069	15	+	26472758	Raji	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	0.0034325713346911035	[373]	[86]	0	hSpCas9	negative selection	478117
66435078	66435101	15	+	26472758	Raji	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	-0.5667048558205405	[216]	[33]	-4	hSpCas9	negative selection	478118
66436842	66436865	15	+	26472758	Raji	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.4641584495852352	[534]	[89]	-4	hSpCas9	negative selection	478119
66487235	66487258	15	+	26472758	Raji	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	-0.008093682046336426	[701]	[161]	0	hSpCas9	negative selection	478120
66435105	66435128	15	+	26472758	Raji	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-0.9096899779853419	[169]	[20]	-6	hSpCas9	negative selection	478121
66435039	66435062	15	+	26472758	K562	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-2.2300672366931398	[577]	[103]	-7	hSpCas9	negative selection	669230
66481763	66481786	15	-	26472758	K562	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	0.32242123966771996	[503]	[531]	2	hSpCas9	negative selection	669231
66435117	66435140	15	+	26472758	K562	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-0.5745783071659509	[590]	[334]	-4	hSpCas9	negative selection	669232
66444686	66444709	15	+	26472758	K562	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	1.1737267893825625	[595]	[1134]	8	hSpCas9	negative selection	669233
66481851	66481874	15	-	26472758	K562	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	0.40231404024755957	[1123]	[1253]	3	hSpCas9	negative selection	669234
66485046	66485069	15	+	26472758	K562	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	0.060687926699104056	[944]	[831]	0	hSpCas9	negative selection	669235
66435078	66435101	15	+	26472758	K562	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	0.8325836604259469	[299]	[450]	7	hSpCas9	negative selection	669236
66436842	66436865	15	+	26472758	K562	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.010554007162480339	[988]	[840]	0	hSpCas9	negative selection	669237
66487235	66487258	15	+	26472758	K562	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	0.07213136276704213	[1145]	[1016]	0	hSpCas9	negative selection	669238
66435105	66435128	15	+	26472758	K562	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	0.37934830775255546	[203]	[223]	3	hSpCas9	negative selection	669239
66387415	66387438	15	-	26627737	DLD1	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.4605872191109175	[1099]	[273,308,179]	-5	hSpCas9	negative selection	791414
66436842	66436865	15	+	26627737	DLD1	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.9478576954457592	[922]	[161,129,154]	-7	hSpCas9	negative selection	791415
66481769	66481792	15	+	26627737	DLD1	viability	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.02172303998923311	[540]	[194,145,158]	0	hSpCas9	negative selection	791416
66387415	66387438	15	-	26627737	GBM cells	viability after 5 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.0267748167614541	[463]	[296,209]	0	hSpCas9	negative selection	873729
66436842	66436865	15	+	26627737	GBM cells	viability after 5 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.1584193001802661	[307]	[147,147]	-2	hSpCas9	negative selection	873730
66481769	66481792	15	+	26627737	GBM cells	viability after 5 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.33935629095476705	[334]	[94,188]	-5	hSpCas9	negative selection	873731
66387415	66387438	15	-	26627737	GBM cells	viability after 13 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.24780446140226042	[463]	[379,232]	3	hSpCas9	negative selection	956044
66436842	66436865	15	+	26627737	GBM cells	viability after 13 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.14227986089922148	[307]	[162,141]	-2	hSpCas9	negative selection	956045
66481769	66481792	15	+	26627737	GBM cells	viability after 13 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	0.4246927430341823	[334]	[270,221]	5	hSpCas9	negative selection	956046
66387415	66387438	15	-	26627737	GBM cells	viability after 21 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.6062961305161391	[463]	[412,356]	6	hSpCas9	negative selection	1038359
66436842	66436865	15	+	26627737	GBM cells	viability after 21 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.23556489937529823	[307]	[150,133]	-2	hSpCas9	negative selection	1038360
66481769	66481792	15	+	26627737	GBM cells	viability after 21 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.3410908543332983	[334]	[162,125]	-3	hSpCas9	negative selection	1038361
66387415	66387438	15	-	26627737	RPE1	viability after 9 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.01845034195950046	[1374]	[486,344]	0	hSpCas9	negative selection	1120674
66436842	66436865	15	+	26627737	RPE1	viability after 9 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.10831867934953437	[1103]	[286,482]	0	hSpCas9	negative selection	1120675
66481769	66481792	15	+	26627737	RPE1	viability after 9 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	0.6458771346506208	[1098]	[433,672]	4	hSpCas9	negative selection	1120676
66387415	66387438	15	-	26627737	RPE1	viability after 12 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.27022339162118925	[1374]	[564,318]	1	hSpCas9	negative selection	1202989
66436842	66436865	15	+	26627737	RPE1	viability after 12 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.1299598302225421	[1103]	[272,268]	-1	hSpCas9	negative selection	1202990
66481769	66481792	15	+	26627737	RPE1	viability after 12 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	0.49219542801305594	[1098]	[442,385]	3	hSpCas9	negative selection	1202991
66387415	66387438	15	-	26627737	RPE1	viability after 15 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.2872718104166031	[1374]	[718,238]	1	hSpCas9	negative selection	1285304
66436842	66436865	15	+	26627737	RPE1	viability after 15 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.8069587477336486	[1103]	[121,232]	-5	hSpCas9	negative selection	1285305
66481769	66481792	15	+	26627737	RPE1	viability after 15 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	0.9870418472280292	[1098]	[688,545]	6	hSpCas9	negative selection	1285306
66387415	66387438	15	-	26627737	RPE1	viability after 18 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.5361053410742028	[1374]	[510,566]	3	hSpCas9	negative selection	1367619
66436842	66436865	15	+	26627737	RPE1	viability after 18 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.08894350417440072	[1103]	[327,304]	0	hSpCas9	negative selection	1367620
66481769	66481792	15	+	26627737	RPE1	viability after 18 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	0.7722932775744661	[1098]	[420,597]	5	hSpCas9	negative selection	1367621
66387415	66387438	15	-	26627737	HeLa	viability after 8 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.16711546480217399	[736]	[350,319,205]	-1	hSpCas9	negative selection	1449934
66436842	66436865	15	+	26627737	HeLa	viability after 8 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.0057040008672905596	[480]	[263,208,171]	0	hSpCas9	negative selection	1449935
66481769	66481792	15	+	26627737	HeLa	viability after 8 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.23137329148765495	[510]	[204,300,73]	-2	hSpCas9	negative selection	1449936
66387415	66387438	15	-	26627737	HeLa	viability after 12 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.1588860437736931	[736]	[198,369,236]	-1	hSpCas9	negative selection	1532249
66436842	66436865	15	+	26627737	HeLa	viability after 12 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.8584329080057025	[480]	[84,35,214]	-7	hSpCas9	negative selection	1532250
66481769	66481792	15	+	26627737	HeLa	viability after 12 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.10534906649259862	[510]	[149,314,109]	-1	hSpCas9	negative selection	1532251
66387415	66387438	15	-	26627737	HeLa	viability after 15 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.6791040830002644	[736]	[184,167,210]	-5	hSpCas9	negative selection	1614564
66436842	66436865	15	+	26627737	HeLa	viability after 15 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.35035227166003674	[480]	[137,120,205]	-3	hSpCas9	negative selection	1614565
66481769	66481792	15	+	26627737	HeLa	viability after 15 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.6752926316983385	[510]	[28,197,167]	-5	hSpCas9	negative selection	1614566
66387415	66387438	15	-	26627737	HeLa	viability after 18 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.6863084690166703	[736]	[123,136,210]	-6	hSpCas9	negative selection	1696879
66436842	66436865	15	+	26627737	HeLa	viability after 18 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.32520431035060104	[480]	[97,99,205]	-3	hSpCas9	negative selection	1696880
66481769	66481792	15	+	26627737	HeLa	viability after 18 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.6640480838109686	[510]	[18,166,167]	-5	hSpCas9	negative selection	1696881
66387415	66387438	15	-	26627737	HCT116	viability after 6 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.5092451960894451	[1456]	[403,282]	3	hSpCas9	negative selection	1779194
66436842	66436865	15	+	26627737	HCT116	viability after 6 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.7069365177994603	[747]	[510,15]	4	hSpCas9	negative selection	1779195
66481769	66481792	15	+	26627737	HCT116	viability after 6 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.048515214899004344	[1110]	[77,218]	0	hSpCas9	negative selection	1779196
66387415	66387438	15	-	26627737	HCT116	viability after 8 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	1.186158889074542	[275]	[323,302,409]	8	hSpCas9	negative selection	1861509
66436842	66436865	15	+	26627737	HCT116	viability after 8 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.464157125455832	[368]	[216,126,99]	-5	hSpCas9	negative selection	1861510
66481769	66481792	15	+	26627737	HCT116	viability after 8 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.1838260713943777	[300]	[145,141,149]	-2	hSpCas9	negative selection	1861511
66387415	66387438	15	-	26627737	HCT116	viability after 9 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.22895214267939212	[1456]	[546,383]	1	hSpCas9	negative selection	1943824
66436842	66436865	15	+	26627737	HCT116	viability after 9 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.17415224431414536	[747]	[214,146]	-1	hSpCas9	negative selection	1943825
66481769	66481792	15	+	26627737	HCT116	viability after 9 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.0842060528036459	[1110]	[247,304]	0	hSpCas9	negative selection	1943826
66387415	66387438	15	-	26627737	HCT116	viability after 12 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	1.5029834186624564	[275]	[388,359,484]	9	hSpCas9	negative selection	2026139
66436842	66436865	15	+	26627737	HCT116	viability after 12 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.15567772177796352	[368]	[255,193,193]	1	hSpCas9	negative selection	2026140
66481769	66481792	15	+	26627737	HCT116	viability after 12 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	0.5547711711988446	[300]	[214,165,315]	5	hSpCas9	negative selection	2026141
66387415	66387438	15	-	26627737	HCT116	viability after 15 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	1.5109340092985135	[275]	[515,476,370]	9	hSpCas9	negative selection	2108454
66436842	66436865	15	+	26627737	HCT116	viability after 15 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-1.11601979772181	[368]	[73,83,131]	-8	hSpCas9	negative selection	2108455
66481769	66481792	15	+	26627737	HCT116	viability after 15 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.23002293669110171	[300]	[174,79,189]	-2	hSpCas9	negative selection	2108456
66387415	66387438	15	-	26627737	HCT116	viability after 18 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	1.4203890776277523	[275]	[339,384,343]	8	hSpCas9	negative selection	2190769
66436842	66436865	15	+	26627737	HCT116	viability after 18 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.8351115163215345	[368]	[102,72,126]	-6	hSpCas9	negative selection	2190770
66481769	66481792	15	+	26627737	HCT116	viability after 18 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	0.19370023286531945	[300]	[88,37,390]	1	hSpCas9	negative selection	2190771
66387351	66387374	15	-	24336569	HL60	viability	ATGGGCGTCGGCTTCTTCTTGGG	MAP2K1	ENSG00000169032	-1.0757729885510403	[252]	[253]	-7	hSpCas9	negative selection	2275748
66387365	66387388	15	+	24336569	HL60	viability	GACGCCCATCCAGCTGAACCCGG	MAP2K1	ENSG00000169032	0.14475003165996003	[376]	[881]	1	hSpCas9	negative selection	2275749
66387390	66387413	15	-	24336569	HL60	viability	CCGTTAACTGCAGAGCCGTCGGG	MAP2K1	ENSG00000169032	0.6565777300966491	[133]	[446]	5	hSpCas9	negative selection	2275750
66387415	66387438	15	-	24336569	HL60	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.916800848000356	[415]	[1661]	7	hSpCas9	negative selection	2275751
66435015	66435038	15	+	24336569	HL60	viability	ACTTTGGAACAGGACCAACTTGG	MAP2K1	ENSG00000169032	1.6530949958302146	[269]	[1796]	9	hSpCas9	negative selection	2275752
66435039	66435062	15	+	24336569	HL60	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-0.5884240893487793	[134]	[189]	-5	hSpCas9	negative selection	2275753
66435078	66435101	15	+	24336569	HL60	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	0.7858067110451001	[1168]	[4264]	6	hSpCas9	negative selection	2275754
66435101	66435124	15	-	24336569	HL60	viability	CTTCTGCTTCTGGGTAAGAAAGG	MAP2K1	ENSG00000169032	1.1481087430681038	[815]	[3826]	8	hSpCas9	negative selection	2275755
66435106	66435129	15	+	24336569	HL60	viability	CTTACCCAGAAGCAGAAGGTGGG	MAP2K1	ENSG00000169032	-1.242227096859783	[1137]	[1017]	-8	hSpCas9	negative selection	2275756
66435111	66435134	15	-	24336569	HL60	viability	GTTCTCCCACCTTCTGCTTCTGG	MAP2K1	ENSG00000169032	0.5890345847789406	[190]	[607]	5	hSpCas9	negative selection	2275757
66387351	66387374	15	-	24336569	KBM7	viability	ATGGGCGTCGGCTTCTTCTTGGG	MAP2K1	ENSG00000169032	-1.0351388087560778	[138]	[184]	-6	hSpCas9	negative selection	2342925
66387365	66387388	15	+	24336569	KBM7	viability	GACGCCCATCCAGCTGAACCCGG	MAP2K1	ENSG00000169032	-1.0575283807420672	[363]	[476]	-6	hSpCas9	negative selection	2342926
66387390	66387413	15	-	24336569	KBM7	viability	CCGTTAACTGCAGAGCCGTCGGG	MAP2K1	ENSG00000169032	-0.14077238868618314	[210]	[521]	-1	hSpCas9	negative selection	2342927
66387415	66387438	15	-	24336569	KBM7	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.43721248099062315	[415]	[837]	-4	hSpCas9	negative selection	2342928
66435015	66435038	15	+	24336569	KBM7	viability	ACTTTGGAACAGGACCAACTTGG	MAP2K1	ENSG00000169032	0.605872920599849	[509]	[2116]	5	hSpCas9	negative selection	2342929
66435039	66435062	15	+	24336569	KBM7	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-2.441124174411583	[222]	[111]	-8	hSpCas9	negative selection	2342930
66435078	66435101	15	+	24336569	KBM7	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	-0.4416732272511923	[1096]	[2202]	-4	hSpCas9	negative selection	2342931
66435101	66435124	15	-	24336569	KBM7	viability	CTTCTGCTTCTGGGTAAGAAAGG	MAP2K1	ENSG00000169032	0.3897389414800406	[564]	[2018]	3	hSpCas9	negative selection	2342932
66435106	66435129	15	+	24336569	KBM7	viability	CTTACCCAGAAGCAGAAGGTGGG	MAP2K1	ENSG00000169032	-0.4731873961026575	[880]	[1730]	-4	hSpCas9	negative selection	2342933
66435111	66435134	15	-	24336569	KBM7	viability	GTTCTCCCACCTTCTGCTTCTGG	MAP2K1	ENSG00000169032	1.0714092667688697	[260]	[1495]	8	hSpCas9	negative selection	2342934
66447614	66447637	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTACTGCAACCTCCGCCCCCCAG	MAP2K1	ENSG00000169032	-1.8511650686779566	[352,350]	[21,19]	-8	dCas9-VP64	positive selection	2452191
66422673	66422696	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGTTTGACTATGATGTGTCTAGG	MAP2K1	ENSG00000169032	-0.9776001312623527	[52,165]	[12,10]	-6	dCas9-VP64	positive selection	2458243
66447614	66447637	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTACTGCAACCTCCGCCCCCCAG	MAP2K1	ENSG00000169032	0.9477034237395038	[173,106]	[127,52]	6	dCas9-VP64	positive selection	2547446
66422673	66422696	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGTTTGACTATGATGTGTCTAGG	MAP2K1	ENSG00000169032	-0.07117846671772021	[122,455]	[50,124]	0	dCas9-VP64	positive selection	2553498
66387365	66387388	15	+	27260157	DLD1	viability	GACGCCCATCCAGCTGAACCCGG	MAP2K1	ENSG00000169032	-0.691801543175345	[]	[]	-5	hSpCas9	negative selection	2574576
66387390	66387413	15	+	27260157	DLD1	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.37362590459379	[]	[]	4	hSpCas9	negative selection	2574727
66435102	66435125	15	+	27260157	DLD1	viability	CTTTCTTACCCAGAAGCAGAAGG	MAP2K1	ENSG00000169032	1.57573275829711	[]	[]	9	hSpCas9	negative selection	2578019
66436842	66436865	15	+	27260157	DLD1	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-1.91880192632594	[]	[]	-8	hSpCas9	negative selection	2581082
66435196	66435219	15	+	27260157	DLD1	viability	AAGGTCTCCCACAAGCCTTCTGG	MAP2K1	ENSG00000169032	0.0199837454981516	[]	[]	0	hSpCas9	negative selection	2581853
66435111	66435134	15	-	27260157	DLD1	viability	GTTCTCCCACCTTCTGCTTCTGG	MAP2K1	ENSG00000169032	-0.112647829930874	[]	[]	-1	hSpCas9	negative selection	2583105
66387390	66387413	15	-	27260157	DLD1	viability	CCGTTAACTGCAGAGCCGTCGGG	MAP2K1	ENSG00000169032	-2.37037849222663	[]	[]	-9	hSpCas9	negative selection	2604520
66435219	66435242	15	-	27260157	DLD1	viability	TCACCTTTCTGGCCATGACCAGG	MAP2K1	ENSG00000169032	-0.549279031517489	[]	[]	-4	hSpCas9	negative selection	2605497
66387351	66387374	15	-	27260157	DLD1	viability	ATGGGCGTCGGCTTCTTCTTGGG	MAP2K1	ENSG00000169032	-1.12321644992457	[]	[]	-7	hSpCas9	negative selection	2606232
66435101	66435124	15	-	27260157	DLD1	viability	CTTCTGCTTCTGGGTAAGAAAGG	MAP2K1	ENSG00000169032	-0.421337796353329	[]	[]	-3	hSpCas9	negative selection	2607975
66435015	66435038	15	+	27260157	DLD1	viability	ACTTTGGAACAGGACCAACTTGG	MAP2K1	ENSG00000169032	0.745129995611202	[]	[]	8	hSpCas9	negative selection	2616193
66435110	66435133	15	-	27260157	DLD1	viability	TTCTCCCACCTTCTGCTTCTGGG	MAP2K1	ENSG00000169032	0.829969943924284	[]	[]	9	hSpCas9	negative selection	2616875
66435230	66435253	15	-	27260157	DLD1	viability	TCAAGGCAAACTCACCTTTCTGG	MAP2K1	ENSG00000169032	0.0551424006719843	[]	[]	3	hSpCas9	negative selection	2617128
66435039	66435062	15	+	27260157	DLD1	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-0.623321898949931	[]	[]	-5	hSpCas9	negative selection	2619537
66435078	66435101	15	+	27260157	DLD1	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	1.36215219697346	[]	[]	9	hSpCas9	negative selection	2623899
66435106	66435129	15	+	27260157	DLD1	viability	CTTACCCAGAAGCAGAAGGTGGG	MAP2K1	ENSG00000169032	0.659473288491012	[]	[]	8	hSpCas9	negative selection	2640939
66435117	66435140	15	+	27260157	DLD1	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-0.0376257615653749	[]	[]	0	hSpCas9	negative selection	2642176
66387388	66387411	15	-	27260157	DLD1	viability	GTTAACTGCAGAGCCGTCGGGGG	MAP2K1	ENSG00000169032	-1.30355190714322	[]	[]	-7	hSpCas9	negative selection	2648078
66387415	66387438	15	-	27260157	DLD1	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-1.02533855860884	[]	[]	-7	hSpCas9	negative selection	2649070
66436756	66436779	15	+	27260157	DLD1	viability	TGGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	-0.123134689574019	[]	[]	-1	hSpCas9	negative selection	2649451
66387365	66387388	15	+	27260157	HT1080	viability	GACGCCCATCCAGCTGAACCCGG	MAP2K1	ENSG00000169032	1.47468509229821	[]	[]	9	hSpCas9	negative selection	2650706
66387390	66387413	15	+	27260157	HT1080	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.716898561166039	[]	[]	6	hSpCas9	negative selection	2650857
66435102	66435125	15	+	27260157	HT1080	viability	CTTTCTTACCCAGAAGCAGAAGG	MAP2K1	ENSG00000169032	-0.0606678177837117	[]	[]	0	hSpCas9	negative selection	2654149
66436842	66436865	15	+	27260157	HT1080	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.919312589502254	[]	[]	7	hSpCas9	negative selection	2657212
66435196	66435219	15	+	27260157	HT1080	viability	AAGGTCTCCCACAAGCCTTCTGG	MAP2K1	ENSG00000169032	0.502471687743028	[]	[]	4	hSpCas9	negative selection	2657983
66435111	66435134	15	-	27260157	HT1080	viability	GTTCTCCCACCTTCTGCTTCTGG	MAP2K1	ENSG00000169032	0.753944113647261	[]	[]	6	hSpCas9	negative selection	2659235
66387390	66387413	15	-	27260157	HT1080	viability	CCGTTAACTGCAGAGCCGTCGGG	MAP2K1	ENSG00000169032	-2.9940163047444	[]	[]	-9	hSpCas9	negative selection	2680650
66435219	66435242	15	-	27260157	HT1080	viability	TCACCTTTCTGGCCATGACCAGG	MAP2K1	ENSG00000169032	0.379947048335146	[]	[]	3	hSpCas9	negative selection	2681627
66387351	66387374	15	-	27260157	HT1080	viability	ATGGGCGTCGGCTTCTTCTTGGG	MAP2K1	ENSG00000169032	-0.320720120135475	[]	[]	-7	hSpCas9	negative selection	2682362
66435101	66435124	15	-	27260157	HT1080	viability	CTTCTGCTTCTGGGTAAGAAAGG	MAP2K1	ENSG00000169032	-0.275000157158249	[]	[]	-4	hSpCas9	negative selection	2684105
66435015	66435038	15	+	27260157	HT1080	viability	ACTTTGGAACAGGACCAACTTGG	MAP2K1	ENSG00000169032	0.243797888937589	[]	[]	2	hSpCas9	negative selection	2692323
66435110	66435133	15	-	27260157	HT1080	viability	TTCTCCCACCTTCTGCTTCTGGG	MAP2K1	ENSG00000169032	0.132724125371366	[]	[]	1	hSpCas9	negative selection	2693005
66435230	66435253	15	-	27260157	HT1080	viability	TCAAGGCAAACTCACCTTTCTGG	MAP2K1	ENSG00000169032	0.354761705422375	[]	[]	3	hSpCas9	negative selection	2693258
66435039	66435062	15	+	27260157	HT1080	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	0.0439354196859536	[]	[]	0	hSpCas9	negative selection	2695667
66435078	66435101	15	+	27260157	HT1080	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	0.486911810025427	[]	[]	4	hSpCas9	negative selection	2700029
66435106	66435129	15	+	27260157	HT1080	viability	CTTACCCAGAAGCAGAAGGTGGG	MAP2K1	ENSG00000169032	-0.446931757933567	[]	[]	-7	hSpCas9	negative selection	2717069
66435117	66435140	15	+	27260157	HT1080	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-0.879938378700273	[]	[]	-8	hSpCas9	negative selection	2718306
66387388	66387411	15	-	27260157	HT1080	viability	GTTAACTGCAGAGCCGTCGGGGG	MAP2K1	ENSG00000169032	-0.646646210656816	[]	[]	-8	hSpCas9	negative selection	2724208
66387415	66387438	15	-	27260157	HT1080	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.692563207428597	[]	[]	-8	hSpCas9	negative selection	2725200
66436756	66436779	15	+	27260157	HT1080	viability	TGGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	0.487211923526994	[]	[]	4	hSpCas9	negative selection	2725581
66387365	66387388	15	+	27260157	MKN45	viability	GACGCCCATCCAGCTGAACCCGG	MAP2K1	ENSG00000169032	1.04750791363414	[]	[]	8	hSpCas9	negative selection	2726836
66387390	66387413	15	+	27260157	MKN45	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	1.30656243313779	[]	[]	9	hSpCas9	negative selection	2726987
66435102	66435125	15	+	27260157	MKN45	viability	CTTTCTTACCCAGAAGCAGAAGG	MAP2K1	ENSG00000169032	-0.161085555852919	[]	[]	0	hSpCas9	negative selection	2730279
66436842	66436865	15	+	27260157	MKN45	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.944061416029312	[]	[]	8	hSpCas9	negative selection	2733342
66435196	66435219	15	+	27260157	MKN45	viability	AAGGTCTCCCACAAGCCTTCTGG	MAP2K1	ENSG00000169032	0.86741748687032	[]	[]	8	hSpCas9	negative selection	2734113
66435111	66435134	15	-	27260157	MKN45	viability	GTTCTCCCACCTTCTGCTTCTGG	MAP2K1	ENSG00000169032	0.788913201755149	[]	[]	7	hSpCas9	negative selection	2735365
66387390	66387413	15	-	27260157	MKN45	viability	CCGTTAACTGCAGAGCCGTCGGG	MAP2K1	ENSG00000169032	-3.41370573104558	[]	[]	-9	hSpCas9	negative selection	2756780
66435219	66435242	15	-	27260157	MKN45	viability	TCACCTTTCTGGCCATGACCAGG	MAP2K1	ENSG00000169032	0.572792766865053	[]	[]	7	hSpCas9	negative selection	2757757
66387351	66387374	15	-	27260157	MKN45	viability	ATGGGCGTCGGCTTCTTCTTGGG	MAP2K1	ENSG00000169032	0.322146229212868	[]	[]	5	hSpCas9	negative selection	2758492
66435101	66435124	15	-	27260157	MKN45	viability	CTTCTGCTTCTGGGTAAGAAAGG	MAP2K1	ENSG00000169032	0.119382829719762	[]	[]	4	hSpCas9	negative selection	2760235
66435015	66435038	15	+	27260157	MKN45	viability	ACTTTGGAACAGGACCAACTTGG	MAP2K1	ENSG00000169032	1.69934473058293	[]	[]	9	hSpCas9	negative selection	2768453
66435110	66435133	15	-	27260157	MKN45	viability	TTCTCCCACCTTCTGCTTCTGGG	MAP2K1	ENSG00000169032	-0.0911207756562524	[]	[]	0	hSpCas9	negative selection	2769135
66435230	66435253	15	-	27260157	MKN45	viability	TCAAGGCAAACTCACCTTTCTGG	MAP2K1	ENSG00000169032	-0.30228009692781	[]	[]	-1	hSpCas9	negative selection	2769388
66435039	66435062	15	+	27260157	MKN45	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-1.06969986929574	[]	[]	-8	hSpCas9	negative selection	2771797
66435078	66435101	15	+	27260157	MKN45	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	0.48756827504188	[]	[]	6	hSpCas9	negative selection	2776159
66435106	66435129	15	+	27260157	MKN45	viability	CTTACCCAGAAGCAGAAGGTGGG	MAP2K1	ENSG00000169032	-0.410085198379206	[]	[]	-6	hSpCas9	negative selection	2793199
66435117	66435140	15	+	27260157	MKN45	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-1.42692196620267	[]	[]	-8	hSpCas9	negative selection	2794436
66387388	66387411	15	-	27260157	MKN45	viability	GTTAACTGCAGAGCCGTCGGGGG	MAP2K1	ENSG00000169032	-1.19535641520356	[]	[]	-8	hSpCas9	negative selection	2800338
66387415	66387438	15	-	27260157	MKN45	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-1.34514565500578	[]	[]	-8	hSpCas9	negative selection	2801330
66436756	66436779	15	+	27260157	MKN45	viability	TGGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	-0.434697152983203	[]	[]	-6	hSpCas9	negative selection	2801711
66387365	66387388	15	+	27260157	RKO	viability	GACGCCCATCCAGCTGAACCCGG	MAP2K1	ENSG00000169032	1.48431680589756	[]	[]	9	hSpCas9	negative selection	2802966
66387390	66387413	15	+	27260157	RKO	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	1.15016144363849	[]	[]	9	hSpCas9	negative selection	2803117
66435102	66435125	15	+	27260157	RKO	viability	CTTTCTTACCCAGAAGCAGAAGG	MAP2K1	ENSG00000169032	-0.974785565299776	[]	[]	-8	hSpCas9	negative selection	2806409
66436842	66436865	15	+	27260157	RKO	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.868116514196785	[]	[]	-8	hSpCas9	negative selection	2809472
66435196	66435219	15	+	27260157	RKO	viability	AAGGTCTCCCACAAGCCTTCTGG	MAP2K1	ENSG00000169032	0.902154706723559	[]	[]	8	hSpCas9	negative selection	2810243
66435111	66435134	15	-	27260157	RKO	viability	GTTCTCCCACCTTCTGCTTCTGG	MAP2K1	ENSG00000169032	0.0903750082168385	[]	[]	0	hSpCas9	negative selection	2811495
66387390	66387413	15	-	27260157	RKO	viability	CCGTTAACTGCAGAGCCGTCGGG	MAP2K1	ENSG00000169032	-1.78623468923089	[]	[]	-9	hSpCas9	negative selection	2832910
66435219	66435242	15	-	27260157	RKO	viability	TCACCTTTCTGGCCATGACCAGG	MAP2K1	ENSG00000169032	0.773609519256277	[]	[]	8	hSpCas9	negative selection	2833887
66387351	66387374	15	-	27260157	RKO	viability	ATGGGCGTCGGCTTCTTCTTGGG	MAP2K1	ENSG00000169032	-0.200656240610575	[]	[]	-1	hSpCas9	negative selection	2834622
66435101	66435124	15	-	27260157	RKO	viability	CTTCTGCTTCTGGGTAAGAAAGG	MAP2K1	ENSG00000169032	0.429097191622217	[]	[]	2	hSpCas9	negative selection	2836365
66435015	66435038	15	+	27260157	RKO	viability	ACTTTGGAACAGGACCAACTTGG	MAP2K1	ENSG00000169032	1.73395267838715	[]	[]	9	hSpCas9	negative selection	2844583
66435110	66435133	15	-	27260157	RKO	viability	TTCTCCCACCTTCTGCTTCTGGG	MAP2K1	ENSG00000169032	-0.717321737931552	[]	[]	-7	hSpCas9	negative selection	2845265
66435230	66435253	15	-	27260157	RKO	viability	TCAAGGCAAACTCACCTTTCTGG	MAP2K1	ENSG00000169032	0.0574651592446154	[]	[]	0	hSpCas9	negative selection	2845518
66435039	66435062	15	+	27260157	RKO	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-1.16982188844225	[]	[]	-8	hSpCas9	negative selection	2847927
66435078	66435101	15	+	27260157	RKO	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	1.70593472507243	[]	[]	9	hSpCas9	negative selection	2852289
66435106	66435129	15	+	27260157	RKO	viability	CTTACCCAGAAGCAGAAGGTGGG	MAP2K1	ENSG00000169032	0.195726347753557	[]	[]	1	hSpCas9	negative selection	2869329
66435117	66435140	15	+	27260157	RKO	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	0.462495312480693	[]	[]	2	hSpCas9	negative selection	2870566
66387388	66387411	15	-	27260157	RKO	viability	GTTAACTGCAGAGCCGTCGGGGG	MAP2K1	ENSG00000169032	-0.181195942594854	[]	[]	-1	hSpCas9	negative selection	2876468
66387415	66387438	15	-	27260157	RKO	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.982361735893642	[]	[]	-8	hSpCas9	negative selection	2877460
66436756	66436779	15	+	27260157	RKO	viability	TGGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	0.523061670765609	[]	[]	2	hSpCas9	negative selection	2877841
66387365	66387388	15	+	27260157	SF268	viability	GACGCCCATCCAGCTGAACCCGG	MAP2K1	ENSG00000169032	0.456551298115867	[]	[]	7	hSpCas9	negative selection	2879096
66387390	66387413	15	+	27260157	SF268	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.73872201330063	[]	[]	8	hSpCas9	negative selection	2879247
66435102	66435125	15	+	27260157	SF268	viability	CTTTCTTACCCAGAAGCAGAAGG	MAP2K1	ENSG00000169032	0.0448185558967006	[]	[]	0	hSpCas9	negative selection	2882539
66436842	66436865	15	+	27260157	SF268	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-1.27386517340574	[]	[]	-7	hSpCas9	negative selection	2885602
66435196	66435219	15	+	27260157	SF268	viability	AAGGTCTCCCACAAGCCTTCTGG	MAP2K1	ENSG00000169032	0.382041197324388	[]	[]	4	hSpCas9	negative selection	2886373
66435111	66435134	15	-	27260157	SF268	viability	GTTCTCCCACCTTCTGCTTCTGG	MAP2K1	ENSG00000169032	-0.177086078475875	[]	[]	-1	hSpCas9	negative selection	2887625
66387390	66387413	15	-	27260157	SF268	viability	CCGTTAACTGCAGAGCCGTCGGG	MAP2K1	ENSG00000169032	-2.69311932918452	[]	[]	-9	hSpCas9	negative selection	2909040
66435219	66435242	15	-	27260157	SF268	viability	TCACCTTTCTGGCCATGACCAGG	MAP2K1	ENSG00000169032	-0.346827789294238	[]	[]	-3	hSpCas9	negative selection	2910017
66387351	66387374	15	-	27260157	SF268	viability	ATGGGCGTCGGCTTCTTCTTGGG	MAP2K1	ENSG00000169032	-0.862092667595044	[]	[]	-6	hSpCas9	negative selection	2910752
66435101	66435124	15	-	27260157	SF268	viability	CTTCTGCTTCTGGGTAAGAAAGG	MAP2K1	ENSG00000169032	0.69838937570308	[]	[]	8	hSpCas9	negative selection	2912495
66435015	66435038	15	+	27260157	SF268	viability	ACTTTGGAACAGGACCAACTTGG	MAP2K1	ENSG00000169032	0.932824591951408	[]	[]	9	hSpCas9	negative selection	2920713
66435110	66435133	15	-	27260157	SF268	viability	TTCTCCCACCTTCTGCTTCTGGG	MAP2K1	ENSG00000169032	0.294855584243503	[]	[]	4	hSpCas9	negative selection	2921395
66435230	66435253	15	-	27260157	SF268	viability	TCAAGGCAAACTCACCTTTCTGG	MAP2K1	ENSG00000169032	0.0751025326246563	[]	[]	0	hSpCas9	negative selection	2921648
66435039	66435062	15	+	27260157	SF268	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-0.652096615442609	[]	[]	-5	hSpCas9	negative selection	2924057
66435078	66435101	15	+	27260157	SF268	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	0.14069123123682	[]	[]	0	hSpCas9	negative selection	2928419
66435106	66435129	15	+	27260157	SF268	viability	CTTACCCAGAAGCAGAAGGTGGG	MAP2K1	ENSG00000169032	-0.116471016896702	[]	[]	-1	hSpCas9	negative selection	2945459
66435117	66435140	15	+	27260157	SF268	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	0.110217768445898	[]	[]	0	hSpCas9	negative selection	2946696
66387388	66387411	15	-	27260157	SF268	viability	GTTAACTGCAGAGCCGTCGGGGG	MAP2K1	ENSG00000169032	-0.850762420209876	[]	[]	-6	hSpCas9	negative selection	2952598
66387415	66387438	15	-	27260157	SF268	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.748586890951827	[]	[]	-6	hSpCas9	negative selection	2953590
66436756	66436779	15	+	27260157	SF268	viability	TGGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	0.0786580441641695	[]	[]	0	hSpCas9	negative selection	2953971
66444662	66444685	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAAAGGCCTGACATATCTGAGGG	MAP2K1	ENSG00000169032	0.26491927071906646	[2,2]	[3,2]	5	hSpCas9	positive selection	3001102
66436773	66436796	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATCCGGAACCAGATCATAAGGG	MAP2K1	ENSG00000169032	-0.20296874481033866	[3,2]	[2,1]	-3	hSpCas9	positive selection	3001103
66481763	66481786	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	0.322029320298145	[1,2]	[3,1]	6	hSpCas9	positive selection	3001104
66435106	66435129	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-1.047753254136247	[3,2]	[0,0]	-9	hSpCas9	positive selection	3001105
66444662	66444685	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAAAGGCCTGACATATCTGAGGG	MAP2K1	ENSG00000169032	-0.6482001846258921	[2,2]	[0,1]	-8	hSpCas9	positive selection	3068960
66436773	66436796	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATCCGGAACCAGATCATAAGGG	MAP2K1	ENSG00000169032	-0.47710250033108864	[3,3]	[0,1]	-6	hSpCas9	positive selection	3068961
66481763	66481786	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	0.1714687622135136	[1,1]	[2,0]	3	hSpCas9	positive selection	3068962
66435106	66435129	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-0.8294699877703553	[3,3]	[1,0]	-9	hSpCas9	positive selection	3068963
66387415	66387438		-	24336571	A375	resistance to PLX after 7 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.502649826691268	[2,2]	[3,3]	9	hSpCas9	positive selection	3126241
66387390	66387413		+	24336571	A375	resistance to PLX after 7 days	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	-0.2984659991905978	[18,17]	[14,13]	-8	hSpCas9	positive selection	3126242
66435018	66435041		+	24336571	A375	resistance to PLX after 7 days	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.175934780396915	[4,5]	[7,4]	5	hSpCas9	positive selection	3126245
66387415	66387438		-	24336571	A375	resistance to PLX after 14 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	1.157669237211751	[4,1]	[2,3]	8	hSpCas9	positive selection	3184034
66387390	66387413		+	24336571	A375	resistance to PLX after 14 days	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	-0.5922562133323259	[21,14]	[4,5]	-7	hSpCas9	positive selection	3184035
66435018	66435041		+	24336571	A375	resistance to PLX after 14 days	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.2811253100981872	[3,8]	[3,2]	3	hSpCas9	positive selection	3184038
66387415	66387438		-	24336571	A375	viability after 7 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-1.6853094713912815	[10]	[2,2]	-9	hSpCas9	negative selection	3241827
66387390	66387413		+	24336571	A375	viability after 7 days	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.35228613150558025	[14]	[18,17]	5	hSpCas9	negative selection	3241828
66435018	66435041		+	24336571	A375	viability after 7 days	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.8427736043255152	[10]	[4,5]	-8	hSpCas9	negative selection	3241831
66387415	66387438		-	24336571	A375	viability after 14 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-1.4671113180943776	[10]	[4,1]	-9	hSpCas9	negative selection	3299620
66387390	66387413		+	24336571	A375	viability after 14 days	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.3685154636521611	[14]	[21,14]	5	hSpCas9	negative selection	3299621
66435018	66435041		+	24336571	A375	viability after 14 days	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.6601351271189053	[10]	[3,8]	-7	hSpCas9	negative selection	3299624
66435018	66435041	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.9858477720271158	[302,302]	[0,0]	-6	hSpCas9	positive selection	3378370
66435177	66435200	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	2.00939869800225	[37,37]	[0,0]	7	hSpCas9	positive selection	3378371
66436736	66436759	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	-0.600654783681737	[231,231]	[0,0]	-4	hSpCas9	positive selection	3378372
66444661	66444684	15	+	26780180	HT29	viability (Avana library 4 designs)	AAAAGGCCTGACATATCTGAGGG	MAP2K1	ENSG00000169032	4.14148739549076	[]	[]	9	hSpCas9	negative selection	3438744
66436772	66436795	15	+	26780180	HT29	viability (Avana library 4 designs)	AATCCGGAACCAGATCATAAGGG	MAP2K1	ENSG00000169032	3.08373130732317	[]	[]	8	hSpCas9	negative selection	3438745
66481763	66481786	15	-	26780180	HT29	viability (Avana library 4 designs)	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	3.06058309079023	[]	[]	8	hSpCas9	negative selection	3438746
66435105	66435128	15	+	26780180	HT29	viability (Avana library 4 designs)	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	4.41165891195402	[]	[]	9	hSpCas9	negative selection	3438747
66481763	66481786	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-17.1463195444661	[]	[]	-9	hSpCas9	negative selection	3528147
66435105	66435128	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-8.50530028462479	[]	[]	-7	hSpCas9	negative selection	3528148
66436772	66436795	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATCCGGAACCAGATCATAAGGG	MAP2K1	ENSG00000169032	-4.65413485761975	[]	[]	-5	hSpCas9	negative selection	3528149
66444661	66444684	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAAAGGCCTGACATATCTGAGGG	MAP2K1	ENSG00000169032	-15.9633459915735	[]	[]	-9	hSpCas9	negative selection	3528150
66436775	66436798	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCCTTATGATCTGGTTCCGG	MAP2K1	ENSG00000169032	-1.18768023677203	[]	[]	-1	hSpCas9	negative selection	3528151
66443295	66443318	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATCAAGTCCTGAAGAAAGCTGG	MAP2K1	ENSG00000169032	-6.27480659630146	[]	[]	-6	hSpCas9	negative selection	3528152
66481763	66481786	15	-	26780180	A375	viability (Avana lentiGuide)	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	23.4652622841431	[]	[]	9	hSpCas9	negative selection	3636806
66435105	66435128	15	+	26780180	A375	viability (Avana lentiGuide)	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-7.75562602523493	[]	[]	-9	hSpCas9	negative selection	3636807
66436772	66436795	15	+	26780180	A375	viability (Avana lentiGuide)	AATCCGGAACCAGATCATAAGGG	MAP2K1	ENSG00000169032	6.9456127998544	[]	[]	5	hSpCas9	negative selection	3636808
66444661	66444684	15	+	26780180	A375	viability (Avana lentiGuide)	AAAAGGCCTGACATATCTGAGGG	MAP2K1	ENSG00000169032	20.7322898035875	[]	[]	8	hSpCas9	negative selection	3636809
66436775	66436798	15	-	26780180	A375	viability (Avana lentiGuide)	GCTCCCTTATGATCTGGTTCCGG	MAP2K1	ENSG00000169032	24.9238111534671	[]	[]	9	hSpCas9	negative selection	3636810
66443295	66443318	15	+	26780180	A375	viability (Avana lentiGuide)	GATCAAGTCCTGAAGAAAGCTGG	MAP2K1	ENSG00000169032	21.3438337083079	[]	[]	9	hSpCas9	negative selection	3636811
66481763	66481786	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-0.35382447120824356	[4]	[4,2]	-5	hSpCas9	positive selection	3745465
66435105	66435128	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	1.354719457332009	[4]	[13,12]	9	hSpCas9	positive selection	3745466
66436772	66436795	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATCCGGAACCAGATCATAAGGG	MAP2K1	ENSG00000169032	-0.26957287000445684	[5]	[5,3]	-4	hSpCas9	positive selection	3745467
66444661	66444684	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAAAGGCCTGACATATCTGAGGG	MAP2K1	ENSG00000169032	-0.921092075291968	[4]	[1,2]	-8	hSpCas9	positive selection	3745468
66436775	66436798	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCCTTATGATCTGGTTCCGG	MAP2K1	ENSG00000169032	0.12710120434822814	[4]	[5,5]	3	hSpCas9	positive selection	3745469
66443295	66443318	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCAAGTCCTGAAGAAAGCTGG	MAP2K1	ENSG00000169032	-0.5541386162986313	[5]	[2,3]	-7	hSpCas9	positive selection	3745470
66481763	66481786	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-0.935602352808551	[4]	[1,2]	-8	hSpCas9	positive selection	3854072
66435105	66435128	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	1.4222788771978814	[5]	[8,16]	9	hSpCas9	positive selection	3854073
66436772	66436795	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATCCGGAACCAGATCATAAGGG	MAP2K1	ENSG00000169032	-0.6416914882710972	[5]	[1,2]	-7	hSpCas9	positive selection	3854074
66444661	66444684	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAAAGGCCTGACATATCTGAGGG	MAP2K1	ENSG00000169032	-0.7467817531027368	[4]	[0,3]	-7	hSpCas9	positive selection	3854075
66436775	66436798	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCCTTATGATCTGGTTCCGG	MAP2K1	ENSG00000169032	-0.49251278914821206	[4]	[2,2]	-6	hSpCas9	positive selection	3854076
66443295	66443318	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCAAGTCCTGAAGAAAGCTGG	MAP2K1	ENSG00000169032	-0.8515809089545913	[5]	[1,2]	-8	hSpCas9	positive selection	3854077
66435177	66435200	15	+	26780180	A375	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	1.1503598643032	[]	[]	6	hSpCas9	negative selection	3959586
66387415	66387438	15	-	26780180	A375	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	1.31979630585999	[]	[]	7	hSpCas9	negative selection	3959587
66387390	66387413	15	+	26780180	A375	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.419467875778285	[]	[]	1	hSpCas9	negative selection	3959588
66436736	66436759	15	+	26780180	A375	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.769333057204048	[]	[]	3	hSpCas9	negative selection	3959589
66436842	66436865	15	+	26780180	A375	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	1.45544860923671	[]	[]	8	hSpCas9	negative selection	3959590
66435018	66435041	15	+	26780180	A375	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	2.26149678214638	[]	[]	9	hSpCas9	negative selection	3959591
66435177	66435200	15	+	26780180	HT29	viability (GeCKOv2 library)	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	1.35337628346258	[]	[]	7	hSpCas9	negative selection	4067552
66387415	66387438	15	-	26780180	HT29	viability (GeCKOv2 library)	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	1.91687204311016	[]	[]	9	hSpCas9	negative selection	4067553
66387390	66387413	15	+	26780180	HT29	viability (GeCKOv2 library)	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	1.37420667914988	[]	[]	7	hSpCas9	negative selection	4067554
66436736	66436759	15	+	26780180	HT29	viability (GeCKOv2 library)	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	1.2731550541863	[]	[]	6	hSpCas9	negative selection	4067555
66436842	66436865	15	+	26780180	HT29	viability (GeCKOv2 library)	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	2.22571432313017	[]	[]	9	hSpCas9	negative selection	4067556
66435018	66435041	15	+	26780180	HT29	viability (GeCKOv2 library)	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	2.15899892681064	[]	[]	9	hSpCas9	negative selection	4067557
66387415	66387438	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.20472513434272277	[2]	[0,1]	-5	hSpCas9	positive selection	4150457
66387390	66387413	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	-0.1128189568982884	[4]	[2,2]	-3	hSpCas9	positive selection	4150458
66435018	66435041	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.2621285354126643	[3]	[1,1]	-6	hSpCas9	positive selection	4150461
66387415	66387438	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.31116303583765936	[1]	[0,0,0,0]	-5	hSpCas9	positive selection	4214479
66387390	66387413	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.23017403782507678	[4]	[3,2,3,0]	1	hSpCas9	positive selection	4214480
66435018	66435041	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	1.9387852871940336	[1]	[0,4,3,4]	9	hSpCas9	positive selection	4214483
66387415	66387438	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.5602255390176111	[1]	[0,0]	-8	hSpCas9	positive selection	4281798
66436842	66436865	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.8223847621447254	[2]	[0,0]	-9	hSpCas9	positive selection	4281799
66387390	66387413	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.08351230488316701	[2]	[3,1]	1	hSpCas9	positive selection	4281800
66435018	66435041	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.5636805926702599	[3]	[2,0]	-8	hSpCas9	positive selection	4346056
66435177	66435200	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.2981268041559263	[2]	[2,0]	-6	hSpCas9	positive selection	4346057
66436736	66436759	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.3283006256982261	[3]	[3,2]	6	hSpCas9	positive selection	4346058
66435148	66435170	15	+	27760321	OCIAML3	viability	TTTGAGAAGATCAGTGAGCTGG	MAP2K1	ENSG00000169032	0.443724772946837	[263,224]	[240,282]	5	hSpCas9	negative selection	4416540
66436757	66436779	15	+	27760321	OCIAML3	viability	GGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	-0.17496597844826678	[394,288]	[202,275]	-2	hSpCas9	negative selection	4416541
66436843	66436865	15	+	27760321	OCIAML3	viability	ATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.30063561664640137	[752,733]	[620,843]	3	hSpCas9	negative selection	4416542
66485001	66485023	15	-	27760321	OCIAML3	viability	CACAGAGTAATGAGTCCCCTGG	MAP2K1	ENSG00000169032	0.5531359161810453	[556,450]	[576,572]	6	hSpCas9	negative selection	4416543
66485110	66485132	15	+	27760321	OCIAML3	viability	GAGCTGATGTTTGGGTGCCAGG	MAP2K1	ENSG00000169032	0.557264234795595	[1331,1079]	[1202,1611]	6	hSpCas9	negative selection	4416544
66435148	66435170	15	+	27760321	OCIAML2	viability	TTTGAGAAGATCAGTGAGCTGG	MAP2K1	ENSG00000169032	-1.8766834489188167	[263,224]	[57,47]	-9	hSpCas9	negative selection	4500003
66436757	66436779	15	+	27760321	OCIAML2	viability	GGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	-2.871816309793129	[394,288]	[14,66]	-9	hSpCas9	negative selection	4500004
66436843	66436865	15	+	27760321	OCIAML2	viability	ATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-2.5318958406544216	[752,733]	[111,93]	-9	hSpCas9	negative selection	4500005
66485001	66485023	15	-	27760321	OCIAML2	viability	CACAGAGTAATGAGTCCCCTGG	MAP2K1	ENSG00000169032	-2.1937515489936956	[556,450]	[98,74]	-9	hSpCas9	negative selection	4500006
66485110	66485132	15	+	27760321	OCIAML2	viability	GAGCTGATGTTTGGGTGCCAGG	MAP2K1	ENSG00000169032	0.37492582840856525	[1331,1079]	[1109,1453]	5	hSpCas9	negative selection	4500007
66435148	66435170	15	+	27760321	MV411	viability	TTTGAGAAGATCAGTGAGCTGG	MAP2K1	ENSG00000169032	-1.4576447463039064	[263,224]	[0,144]	-7	hSpCas9	negative selection	4583466
66436757	66436779	15	+	27760321	MV411	viability	GGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	0.1778369484074274	[394,288]	[112,462]	1	hSpCas9	negative selection	4583467
66436843	66436865	15	+	27760321	MV411	viability	ATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	1.2913774746696043	[752,733]	[930,1612]	8	hSpCas9	negative selection	4583468
66485001	66485023	15	-	27760321	MV411	viability	CACAGAGTAATGAGTCCCCTGG	MAP2K1	ENSG00000169032	0.9169552522364871	[556,450]	[881,237]	6	hSpCas9	negative selection	4583469
66485110	66485132	15	+	27760321	MV411	viability	GAGCTGATGTTTGGGTGCCAGG	MAP2K1	ENSG00000169032	0.9783463358318762	[1331,1079]	[1404,1791]	7	hSpCas9	negative selection	4583470
66435148	66435170	15	+	27760321	HL60	viability	TTTGAGAAGATCAGTGAGCTGG	MAP2K1	ENSG00000169032	0.1709958017845168	[263,224]	[161,289]	2	hSpCas9	negative selection	4666929
66436757	66436779	15	+	27760321	HL60	viability	GGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	0.3037394108104531	[394,288]	[360,320]	4	hSpCas9	negative selection	4666930
66436843	66436865	15	+	27760321	HL60	viability	ATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.276543709325189	[752,733]	[519,483]	-3	hSpCas9	negative selection	4666931
66485001	66485023	15	-	27760321	HL60	viability	CACAGAGTAATGAGTCCCCTGG	MAP2K1	ENSG00000169032	-0.708815285468015	[556,450]	[135,371]	-6	hSpCas9	negative selection	4666932
66485110	66485132	15	+	27760321	HL60	viability	GAGCTGATGTTTGGGTGCCAGG	MAP2K1	ENSG00000169032	0.5878314428748124	[1331,1079]	[1367,1583]	7	hSpCas9	negative selection	4666933
66435148	66435170	15	+	27760321	HT1080	viability	TTTGAGAAGATCAGTGAGCTGG	MAP2K1	ENSG00000169032	-1.3762248476191679	[224,175]	[25,35]	-5	hSpCas9	negative selection	4750392
66436757	66436779	15	+	27760321	HT1080	viability	GGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	0.9867501201705768	[288,225]	[114,299]	5	hSpCas9	negative selection	4750393
66436843	66436865	15	+	27760321	HT1080	viability	ATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-1.4104618984046526	[733,572]	[64,133]	-5	hSpCas9	negative selection	4750394
66485001	66485023	15	-	27760321	HT1080	viability	CACAGAGTAATGAGTCCCCTGG	MAP2K1	ENSG00000169032	-0.1526344002739446	[450,351]	[267,7]	0	hSpCas9	negative selection	4750395
66485110	66485132	15	+	27760321	HT1080	viability	GAGCTGATGTTTGGGTGCCAGG	MAP2K1	ENSG00000169032	0.14248791227662627	[1079,842]	[270,588]	0	hSpCas9	negative selection	4750396
66435148	66435170	15	+	27760321	HT29	viability after 7 days	TTTGAGAAGATCAGTGAGCTGG	MAP2K1	ENSG00000169032	-0.3255727991706826	[224,175]	[273,189,163]	-5	hSpCas9	negative selection	4833855
66436757	66436779	15	+	27760321	HT29	viability after 7 days	GGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	-0.12319248258714954	[288,225]	[255,320,326]	-2	hSpCas9	negative selection	4833856
66436843	66436865	15	+	27760321	HT29	viability after 7 days	ATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.8361296084771873	[733,572]	[612,361,456]	-8	hSpCas9	negative selection	4833857
66485001	66485023	15	-	27760321	HT29	viability after 7 days	CACAGAGTAATGAGTCCCCTGG	MAP2K1	ENSG00000169032	-0.5582343010141966	[450,351]	[400,388,270]	-7	hSpCas9	negative selection	4833858
66485110	66485132	15	+	27760321	HT29	viability after 7 days	GAGCTGATGTTTGGGTGCCAGG	MAP2K1	ENSG00000169032	0.3670219214935815	[1079,842]	[1909,1552,1369]	5	hSpCas9	negative selection	4833859
66435148	66435170	15	+	27760321	HT29	viability after 25 days	TTTGAGAAGATCAGTGAGCTGG	MAP2K1	ENSG00000169032	-2.865544096346739	[224,175]	[12,28,55]	-8	hSpCas9	negative selection	4917318
66436757	66436779	15	+	27760321	HT29	viability after 25 days	GGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	-2.7273237368682346	[288,225]	[39,70,19]	-8	hSpCas9	negative selection	4917319
66436843	66436865	15	+	27760321	HT29	viability after 25 days	ATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-3.2000978602099313	[733,572]	[81,102,55]	-8	hSpCas9	negative selection	4917320
66485001	66485023	15	-	27760321	HT29	viability after 25 days	CACAGAGTAATGAGTCCCCTGG	MAP2K1	ENSG00000169032	-3.384595217339134	[450,351]	[17,65,49]	-9	hSpCas9	negative selection	4917321
66485110	66485132	15	+	27760321	HT29	viability after 25 days	GAGCTGATGTTTGGGTGCCAGG	MAP2K1	ENSG00000169032	0.3139496880935533	[1079,842]	[1293,1365,1448]	3	hSpCas9	negative selection	4917322
66435148	66435170	15	+	27760321	HT29	viability after 22 days	TTTGAGAAGATCAGTGAGCTGG	MAP2K1	ENSG00000169032	-2.3546897027905636	[224,175]	[43,46,44]	-8	hSpCas9	negative selection	5000781
66436757	66436779	15	+	27760321	HT29	viability after 22 days	GGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	-1.3070941732752197	[288,225]	[93,111,155]	-7	hSpCas9	negative selection	5000782
66436843	66436865	15	+	27760321	HT29	viability after 22 days	ATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-3.4557115881882527	[733,572]	[44,115,45]	-9	hSpCas9	negative selection	5000783
66485001	66485023	15	-	27760321	HT29	viability after 22 days	CACAGAGTAATGAGTCCCCTGG	MAP2K1	ENSG00000169032	-2.5878960849691106	[450,351]	[19,46,166]	-8	hSpCas9	negative selection	5000784
66485110	66485132	15	+	27760321	HT29	viability after 22 days	GAGCTGATGTTTGGGTGCCAGG	MAP2K1	ENSG00000169032	0.28234714261421323	[1079,842]	[1436,1279,1335]	3	hSpCas9	negative selection	5000785
66435148	66435170	15	+	27760321	HT29	viability after 19 days	TTTGAGAAGATCAGTGAGCTGG	MAP2K1	ENSG00000169032	-2.7989955080833635	[224,175]	[75,11,15]	-8	hSpCas9	negative selection	5084244
66436757	66436779	15	+	27760321	HT29	viability after 19 days	GGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	-2.2555950807375598	[288,225]	[127,3,59]	-8	hSpCas9	negative selection	5084245
66436843	66436865	15	+	27760321	HT29	viability after 19 days	ATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-1.3892809331842613	[733,572]	[137,326,371]	-7	hSpCas9	negative selection	5084246
66485001	66485023	15	-	27760321	HT29	viability after 19 days	CACAGAGTAATGAGTCCCCTGG	MAP2K1	ENSG00000169032	-2.2970560613122424	[450,351]	[181,53,54]	-8	hSpCas9	negative selection	5084247
66485110	66485132	15	+	27760321	HT29	viability after 19 days	GAGCTGATGTTTGGGTGCCAGG	MAP2K1	ENSG00000169032	0.8001034405632319	[1079,842]	[1662,1774,2264]	7	hSpCas9	negative selection	5084248
66435148	66435170	15	+	27760321	HT29	viability after 16 days	TTTGAGAAGATCAGTGAGCTGG	MAP2K1	ENSG00000169032	-2.6838113775757586	[224,175]	[71,5,30]	-8	hSpCas9	negative selection	5167707
66436757	66436779	15	+	27760321	HT29	viability after 16 days	GGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	-0.8077500450422476	[288,225]	[99,36,353]	-6	hSpCas9	negative selection	5167708
66436843	66436865	15	+	27760321	HT29	viability after 16 days	ATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-2.5576998541365046	[733,572]	[102,220,43]	-8	hSpCas9	negative selection	5167709
66485001	66485023	15	-	27760321	HT29	viability after 16 days	CACAGAGTAATGAGTCCCCTGG	MAP2K1	ENSG00000169032	-1.1182552595629904	[450,351]	[213,145,262]	-7	hSpCas9	negative selection	5167710
66485110	66485132	15	+	27760321	HT29	viability after 16 days	GAGCTGATGTTTGGGTGCCAGG	MAP2K1	ENSG00000169032	0.41161761234098737	[1079,842]	[1679,1241,1398]	4	hSpCas9	negative selection	5167711
66435148	66435170	15	+	27760321	HT29	viability after 13 days	TTTGAGAAGATCAGTGAGCTGG	MAP2K1	ENSG00000169032	-1.2909035575964438	[224,175]	[105,97,81]	-8	hSpCas9	negative selection	5251170
66436757	66436779	15	+	27760321	HT29	viability after 13 days	GGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	-1.0833348377142484	[288,225]	[100,162,157]	-7	hSpCas9	negative selection	5251171
66436843	66436865	15	+	27760321	HT29	viability after 13 days	ATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-1.5745813031823168	[733,572]	[246,217,295]	-8	hSpCas9	negative selection	5251172
66485001	66485023	15	-	27760321	HT29	viability after 13 days	CACAGAGTAATGAGTCCCCTGG	MAP2K1	ENSG00000169032	-2.280523269455976	[450,351]	[48,164,74]	-9	hSpCas9	negative selection	5251173
66485110	66485132	15	+	27760321	HT29	viability after 13 days	GAGCTGATGTTTGGGTGCCAGG	MAP2K1	ENSG00000169032	0.7148832345385572	[1079,842]	[1909,2091,1509]	8	hSpCas9	negative selection	5251174
66435148	66435170	15	+	27760321	HT29	viability after 10 days	TTTGAGAAGATCAGTGAGCTGG	MAP2K1	ENSG00000169032	-0.09938151184465005	[224,175]	[204,204,288]	-1	hSpCas9	negative selection	5334633
66436757	66436779	15	+	27760321	HT29	viability after 10 days	GGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	0.06871170090300616	[288,225]	[182,533,300]	0	hSpCas9	negative selection	5334634
66436843	66436865	15	+	27760321	HT29	viability after 10 days	ATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-1.2495677233067064	[733,572]	[335,517,183]	-8	hSpCas9	negative selection	5334635
66485001	66485023	15	-	27760321	HT29	viability after 10 days	CACAGAGTAATGAGTCCCCTGG	MAP2K1	ENSG00000169032	-0.7044376429790695	[450,351]	[230,444,251]	-7	hSpCas9	negative selection	5334636
66485110	66485132	15	+	27760321	HT29	viability after 10 days	GAGCTGATGTTTGGGTGCCAGG	MAP2K1	ENSG00000169032	0.43176392610258785	[1079,842]	[1637,1696,1526]	6	hSpCas9	negative selection	5334637
66435148	66435170	15	+	27760321	MOLM13	viability	TTTGAGAAGATCAGTGAGCTGG	MAP2K1	ENSG00000169032	-0.32906192951694047	[263,224]	[62,148]	-2	hSpCas9	negative selection	5418096
66436757	66436779	15	+	27760321	MOLM13	viability	GGAGATCAAACCCGCAATCCGG	MAP2K1	ENSG00000169032	1.115042262975873	[394,288]	[487,350]	7	hSpCas9	negative selection	5418097
66436843	66436865	15	+	27760321	MOLM13	viability	ATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.2811760267582525	[752,733]	[767,291]	2	hSpCas9	negative selection	5418098
66485001	66485023	15	-	27760321	MOLM13	viability	CACAGAGTAATGAGTCCCCTGG	MAP2K1	ENSG00000169032	-0.954420141917991	[556,450]	[159,133]	-5	hSpCas9	negative selection	5418099
66485110	66485132	15	+	27760321	MOLM13	viability	GAGCTGATGTTTGGGTGCCAGG	MAP2K1	ENSG00000169032	0.8505666514956194	[1331,1079]	[1812,715]	6	hSpCas9	negative selection	5418100
66387129	66387152	15	+	27661255	K562	viability	GCGCGAAGCCGAGTCCCGGGCGG	MAP2K1	ENSG00000169032	0.16631421351522668	[477,423]	[463,354]	6	dCas9-KRAB	negative selection	5492049
66387388	66387411	15	-	27661255	K562	viability	GTTAACTGCAGAGCCGTCGGGGG	MAP2K1	ENSG00000169032	-0.0010532776775922237	[1599,1446]	[1288,1157]	0	dCas9-KRAB	negative selection	5492050
66387415	66387438	15	-	27260156	BXPC3	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.5167259365253727	[145]	[109,92,105,118]	-8	hSpCas9	negative selection	5554258
66436842	66436865	15	+	27260156	BXPC3	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.21824539340548682	[370]	[283,344,356,352]	-5	hSpCas9	negative selection	5554259
66387390	66387413	15	+	27260156	BXPC3	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.38246341797749606	[400]	[433,462,656,661]	7	hSpCas9	negative selection	5554260
66435018	66435041	15	+	27260156	BXPC3	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.07305921847601632	[608]	[593,662,731,698]	1	hSpCas9	negative selection	5618516
66435177	66435200	15	+	27260156	BXPC3	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.35467675624082307	[206]	[127,110,209,244]	-7	hSpCas9	negative selection	5618517
66436736	66436759	15	+	27260156	BXPC3	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.26137574249636253	[486]	[593,492,670,699]	6	hSpCas9	negative selection	5618518
66387415	66387438	15	-	27260156	A673	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.5999813429876386	[145]	[111,134,151,58]	-9	hSpCas9	negative selection	5675509
66436842	66436865	15	+	27260156	A673	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.3269384826585365	[370]	[483,315,301,332]	-7	hSpCas9	negative selection	5675510
66387390	66387413	15	+	27260156	A673	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.17504681992695212	[400]	[526,448,607,591]	4	hSpCas9	negative selection	5675511
66435018	66435041	15	+	27260156	A673	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.22257262258713095	[608]	[765,634,532,585]	-5	hSpCas9	negative selection	5739767
66435177	66435200	15	+	27260156	A673	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.4638012791435939	[206]	[237,155,139,194]	-8	hSpCas9	negative selection	5739768
66436736	66436759	15	+	27260156	A673	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.2570921886747583	[486]	[668,617,755,751]	6	hSpCas9	negative selection	5739769
66387415	66387438	15	-	27260156	A375	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-1.9760430471685575	[145]	[60,62,44,10]	-9	hSpCas9	negative selection	5796760
66436842	66436865	15	+	27260156	A375	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-2.2696573985795463	[370]	[55,114,125,67]	-9	hSpCas9	negative selection	5796761
66387390	66387413	15	+	27260156	A375	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.5599189472403416	[400]	[654,665,360,1031]	7	hSpCas9	negative selection	5796762
66435018	66435041	15	+	27260156	A375	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-2.2718868281951496	[608]	[140,187,180,90]	-9	hSpCas9	negative selection	5861018
66435177	66435200	15	+	27260156	A375	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-1.355727469771353	[206]	[106,97,86,86]	-9	hSpCas9	negative selection	5861019
66436736	66436759	15	+	27260156	A375	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.18581924326529664	[486]	[875,768,421,548]	2	hSpCas9	negative selection	5861020
66387415	66387438	15	-	27260156	COLO741	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.3253279924859338	[145]	[208,158,87]	-6	hSpCas9	negative selection	5918011
66436842	66436865	15	+	27260156	COLO741	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.7046423150663892	[370]	[403,265,216]	-9	hSpCas9	negative selection	5918012
66387390	66387413	15	+	27260156	COLO741	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.25526836195381336	[400]	[717,539,585]	5	hSpCas9	negative selection	5918013
66435018	66435041	15	+	27260156	COLO741	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.44439723020891414	[608]	[743,447,538]	-7	hSpCas9	negative selection	5982269
66435177	66435200	15	+	27260156	COLO741	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.16939417184078542	[206]	[302,288,126]	-4	hSpCas9	negative selection	5982270
66436736	66436759	15	+	27260156	COLO741	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.5318697840469306	[486]	[904,873,916]	9	hSpCas9	negative selection	5982271
66387415	66387438	15	-	27260156	CAL120	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.0648346208673245	[145]	[132,269,112]	-1	hSpCas9	negative selection	6039262
66436842	66436865	15	+	27260156	CAL120	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.18723918331452644	[370]	[500,232,494]	-3	hSpCas9	negative selection	6039263
66387390	66387413	15	+	27260156	CAL120	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.765024310001134	[400]	[1163,400,1022]	9	hSpCas9	negative selection	6039264
66435018	66435041	15	+	27260156	CAL120	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.06798701245531341	[608]	[822,871,693]	1	hSpCas9	negative selection	6103520
66435177	66435200	15	+	27260156	CAL120	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.5462192658603444	[206]	[197,136,196]	-7	hSpCas9	negative selection	6103521
66436736	66436759	15	+	27260156	CAL120	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.5392769450061387	[486]	[1002,1049,611]	7	hSpCas9	negative selection	6103522
66387415	66387438	15	-	27260156	CADOES1	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.6870874841081835	[145]	[48,54,132,100]	-8	hSpCas9	negative selection	6160513
66436842	66436865	15	+	27260156	CADOES1	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.2426321919554893	[370]	[250,277,416,697]	4	hSpCas9	negative selection	6160514
66387390	66387413	15	+	27260156	CADOES1	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.4354158319388982	[400]	[437,484,678,411]	7	hSpCas9	negative selection	6160515
66435018	66435041	15	+	27260156	CADOES1	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.24740145207453584	[608]	[620,426,411,446]	-4	hSpCas9	negative selection	6224771
66435177	66435200	15	+	27260156	CADOES1	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	0.36221759784714846	[206]	[258,256,222,250]	6	hSpCas9	negative selection	6224772
66436736	66436759	15	+	27260156	CADOES1	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.4275171109890456	[486]	[632,635,498,670]	7	hSpCas9	negative selection	6224773
66387415	66387438	15	-	27260156	EWS502	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.981193839847762	[145]	[65,59,58,133]	-8	hSpCas9	negative selection	6281764
66436842	66436865	15	+	27260156	EWS502	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.23422381974876305	[370]	[543,352,432,514]	4	hSpCas9	negative selection	6281765
66387390	66387413	15	+	27260156	EWS502	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.19609234961304262	[400]	[487,491,490,471]	3	hSpCas9	negative selection	6281766
66435018	66435041	15	+	27260156	EWS502	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.0051948765141435205	[608]	[493,720,642,751]	0	hSpCas9	negative selection	6346022
66435177	66435200	15	+	27260156	EWS502	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	0.22286559898100455	[206]	[227,185,266,354]	4	hSpCas9	negative selection	6346023
66436736	66436759	15	+	27260156	EWS502	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.3567662782136327	[486]	[546,618,724,772]	6	hSpCas9	negative selection	6346024
66387415	66387438	15	-	27260156	EW8	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.4871799062477138	[145]	[89,135,68,45]	-7	hSpCas9	negative selection	6403015
66436842	66436865	15	+	27260156	EW8	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.08225391249477593	[370]	[318,245,306,262]	-1	hSpCas9	negative selection	6403016
66387390	66387413	15	+	27260156	EW8	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.3437570970259219	[400]	[485,477,311,397]	6	hSpCas9	negative selection	6403017
66435018	66435041	15	+	27260156	EW8	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.07817432155468473	[608]	[522,506,240,641]	-1	hSpCas9	negative selection	6467273
66435177	66435200	15	+	27260156	EW8	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.027779325578419112	[206]	[295,162,107,114]	0	hSpCas9	negative selection	6467274
66436736	66436759	15	+	27260156	EW8	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.503841462070501	[486]	[805,493,362,633]	8	hSpCas9	negative selection	6467275
66387415	66387438	15	-	27260156	CORL105	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.003532503909751794	[145]	[204,125,151,197]	0	hSpCas9	negative selection	6524266
66436842	66436865	15	+	27260156	CORL105	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.053713539583297276	[370]	[396,435,414,423]	-1	hSpCas9	negative selection	6524267
66387390	66387413	15	+	27260156	CORL105	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.5711270422494044	[400]	[747,805,579,636]	9	hSpCas9	negative selection	6524268
66435018	66435041	15	+	27260156	CORL105	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.051886589787282056	[608]	[740,607,744,864]	1	hSpCas9	negative selection	6588524
66435177	66435200	15	+	27260156	CORL105	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.06962364188975445	[206]	[233,260,266,166]	-1	hSpCas9	negative selection	6588525
66436736	66436759	15	+	27260156	CORL105	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.2800864587021402	[486]	[779,526,655,805]	5	hSpCas9	negative selection	6588526
66387415	66387438	15	-	27260156	HS294T	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.8734291494689483	[145]	[14,46,21,41]	-8	hSpCas9	negative selection	6645517
66436842	66436865	15	+	27260156	HS294T	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.49624649888451805	[370]	[88,93,112,113]	-6	hSpCas9	negative selection	6645518
66387390	66387413	15	+	27260156	HS294T	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.635686676989509	[400]	[320,176,153,317]	8	hSpCas9	negative selection	6645519
66435018	66435041	15	+	27260156	HS294T	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.49229314542295827	[608]	[118,210,160,183]	-6	hSpCas9	negative selection	6709775
66435177	66435200	15	+	27260156	HS294T	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.1692832288438002	[206]	[56,118,52,51]	-2	hSpCas9	negative selection	6709776
66436736	66436759	15	+	27260156	HS294T	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	-0.07448778548049081	[486]	[196,157,167,192]	-1	hSpCas9	negative selection	6709777
66387415	66387438	15	-	27260156	HCC44	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.11305272471952033	[145]	[135,63,338,114]	-2	hSpCas9	negative selection	6766768
66436842	66436865	15	+	27260156	HCC44	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.0277018661733493	[370]	[349,232,553,545]	0	hSpCas9	negative selection	6766769
66387390	66387413	15	+	27260156	HCC44	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.6600585066542892	[400]	[677,755,816,620]	9	hSpCas9	negative selection	6766770
66435018	66435041	15	+	27260156	HCC44	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.4687881966141007	[608]	[605,443,489,463]	-6	hSpCas9	negative selection	6831026
66435177	66435200	15	+	27260156	HCC44	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	0.022427971556477244	[206]	[264,101,107,465]	0	hSpCas9	negative selection	6831027
66436736	66436759	15	+	27260156	HCC44	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.6217010613264483	[486]	[824,784,1157,680]	8	hSpCas9	negative selection	6831028
66387415	66387438	15	-	27260156	G402	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.809183691768453	[145]	[14,188,159,37]	-7	hSpCas9	negative selection	6888019
66436842	66436865	15	+	27260156	G402	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.585466470936999	[370]	[284,172,293,436]	-6	hSpCas9	negative selection	6888020
66387390	66387413	15	+	27260156	G402	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.5590209811358684	[400]	[778,1139,560,446]	7	hSpCas9	negative selection	6888021
66435018	66435041	15	+	27260156	G402	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.2237150961585365	[608]	[848,1050,489,227]	-3	hSpCas9	negative selection	6952277
66435177	66435200	15	+	27260156	G402	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.6488837510860166	[206]	[124,212,236,70]	-7	hSpCas9	negative selection	6952278
66436736	66436759	15	+	27260156	G402	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.7576256953559916	[486]	[1430,1076,724,854]	8	hSpCas9	negative selection	6952279
66387415	66387438	15	-	27260156	L33	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.4926141977065035	[145]	[110,43,52,111]	-8	hSpCas9	negative selection	7009270
66436842	66436865	15	+	27260156	L33	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.19550960053462413	[370]	[402,155,218,565]	4	hSpCas9	negative selection	7009271
66387390	66387413	15	+	27260156	L33	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.1417792155487698	[400]	[341,160,334,503]	3	hSpCas9	negative selection	7009272
66435018	66435041	15	+	27260156	L33	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.1540704726070194	[608]	[898,232,391,613]	3	hSpCas9	negative selection	7073528
66435177	66435200	15	+	27260156	L33	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.45781293551361446	[206]	[166,59,101,126]	-8	hSpCas9	negative selection	7073529
66436736	66436759	15	+	27260156	L33	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.24328891843971334	[486]	[566,250,313,625]	5	hSpCas9	negative selection	7073530
66387415	66387438	15	-	27260156	K562	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.8062926517108095	[145]	[164,71,16,51]	-7	hSpCas9	negative selection	7130521
66436842	66436865	15	+	27260156	K562	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.6499582338634777	[370]	[207,350,164,130]	-6	hSpCas9	negative selection	7130522
66387390	66387413	15	+	27260156	K562	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.4359791228173401	[400]	[277,317,675,610]	5	hSpCas9	negative selection	7130523
66435018	66435041	15	+	27260156	K562	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.15910739589603334	[608]	[480,349,925,627]	2	hSpCas9	negative selection	7194779
66435177	66435200	15	+	27260156	K562	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.10078558727067533	[206]	[287,78,101,214]	-1	hSpCas9	negative selection	7194780
66436736	66436759	15	+	27260156	K562	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.8291665706882261	[486]	[954,675,900,569]	9	hSpCas9	negative selection	7194781
66387415	66387438	15	-	27260156	HT29	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-1.038116825373679	[145]	[74,68,105,91]	-8	hSpCas9	negative selection	7251772
66436842	66436865	15	+	27260156	HT29	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.5291356587068297	[370]	[362,400,260,242]	-7	hSpCas9	negative selection	7251773
66387390	66387413	15	+	27260156	HT29	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.5156972108255824	[400]	[662,772,711,644]	8	hSpCas9	negative selection	7251774
66435018	66435041	15	+	27260156	HT29	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.45747282199024575	[608]	[564,605,518,477]	-7	hSpCas9	negative selection	7316030
66435177	66435200	15	+	27260156	HT29	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.46361251577930007	[206]	[159,206,170,189]	-7	hSpCas9	negative selection	7316031
66436736	66436759	15	+	27260156	HT29	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.49495002456622833	[486]	[730,1031,723,850]	8	hSpCas9	negative selection	7316032
66387415	66387438	15	-	27260156	MHHES1	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.36834860630328303	[145]	[168,143,158,57]	-6	hSpCas9	negative selection	7373023
66436842	66436865	15	+	27260156	MHHES1	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.04865990480396076	[370]	[442,460,518,234]	-1	hSpCas9	negative selection	7373024
66387390	66387413	15	+	27260156	MHHES1	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	-0.08754499297388219	[400]	[637,445,436,240]	-2	hSpCas9	negative selection	7373025
66435018	66435041	15	+	27260156	MHHES1	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.535636478029512	[608]	[435,389,517,514]	-7	hSpCas9	negative selection	7437281
66435177	66435200	15	+	27260156	MHHES1	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.07581167535235656	[206]	[293,228,236,146]	-1	hSpCas9	negative selection	7437282
66436736	66436759	15	+	27260156	MHHES1	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.3370905717954555	[486]	[653,786,652,670]	6	hSpCas9	negative selection	7437283
66387415	66387438	15	-	27260156	MEWO	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.5515974502343675	[145]	[79,92,103]	-8	hSpCas9	negative selection	7494274
66436842	66436865	15	+	27260156	MEWO	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.09549530750987573	[370]	[387,272,325]	-2	hSpCas9	negative selection	7494275
66387390	66387413	15	+	27260156	MEWO	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.28126780010083974	[400]	[508,442,425]	6	hSpCas9	negative selection	7494276
66435018	66435041	15	+	27260156	MEWO	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.19444259449120846	[608]	[565,462,477]	-4	hSpCas9	negative selection	7558532
66435177	66435200	15	+	27260156	MEWO	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.5334447054211682	[206]	[187,107,115]	-8	hSpCas9	negative selection	7558533
66436736	66436759	15	+	27260156	MEWO	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.3493566176361995	[486]	[616,644,485]	7	hSpCas9	negative selection	7558534
66387415	66387438	15	-	27260156	LNCAPCLONEFGC	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.9150233837513537	[145]	[69,28,108,80]	-8	hSpCas9	negative selection	7615525
66436842	66436865	15	+	27260156	LNCAPCLONEFGC	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.2571125853893776	[370]	[276,152,427,296]	-4	hSpCas9	negative selection	7615526
66387390	66387413	15	+	27260156	LNCAPCLONEFGC	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.6909564374393289	[400]	[628,487,869,405]	9	hSpCas9	negative selection	7615527
66435018	66435041	15	+	27260156	LNCAPCLONEFGC	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.14382912307429868	[608]	[560,519,774,612]	2	hSpCas9	negative selection	7679783
66435177	66435200	15	+	27260156	LNCAPCLONEFGC	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.17649827258148032	[206]	[96,222,191,152]	-3	hSpCas9	negative selection	7679784
66436736	66436759	15	+	27260156	LNCAPCLONEFGC	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.5684470315302426	[486]	[478,560,856,758]	8	hSpCas9	negative selection	7679785
66387415	66387438	15	-	27260156	PANC0327	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.550558524161451	[145]	[113,82,95,63]	-7	hSpCas9	negative selection	7736776
66436842	66436865	15	+	27260156	PANC0327	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.35454265082133335	[370]	[420,213,236,177]	-5	hSpCas9	negative selection	7736777
66387390	66387413	15	+	27260156	PANC0327	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.44261899727124604	[400]	[528,425,701,290]	6	hSpCas9	negative selection	7736778
66435018	66435041	15	+	27260156	PANC0327	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.14583560855710825	[608]	[735,204,668,402]	-2	hSpCas9	negative selection	7801034
66435177	66435200	15	+	27260156	PANC0327	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	0.08250838812506323	[206]	[242,130,229,186]	1	hSpCas9	negative selection	7801035
66436736	66436759	15	+	27260156	PANC0327	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.3136414620830033	[486]	[548,533,585,482]	4	hSpCas9	negative selection	7801036
66387415	66387438	15	-	27260156	NCIH2009	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.6806075376943526	[145]	[75,96,198]	-7	hSpCas9	negative selection	7858027
66436842	66436865	15	+	27260156	NCIH2009	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.034394508285906567	[370]	[578,429,593]	0	hSpCas9	negative selection	7858028
66387390	66387413	15	+	27260156	NCIH2009	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.7540081522211906	[400]	[924,947,955]	9	hSpCas9	negative selection	7858029
66435018	66435041	15	+	27260156	NCIH2009	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.029197787319477253	[608]	[1326,862,406]	0	hSpCas9	negative selection	7922285
66435177	66435200	15	+	27260156	NCIH2009	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.002306735741715027	[206]	[437,302,153]	0	hSpCas9	negative selection	7922286
66436736	66436759	15	+	27260156	NCIH2009	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.46685603444237095	[486]	[1085,850,912]	6	hSpCas9	negative selection	7922287
66387415	66387438	15	-	27260156	NCIH1373	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-1.6069446322419816	[145]	[58,32,71,13]	-9	hSpCas9	negative selection	7979278
66436842	66436865	15	+	27260156	NCIH1373	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-1.0884694841180957	[370]	[186,322,130,31]	-8	hSpCas9	negative selection	7979279
66387390	66387413	15	+	27260156	NCIH1373	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.44821409539189994	[400]	[669,546,715,137]	4	hSpCas9	negative selection	7979280
66435018	66435041	15	+	27260156	NCIH1373	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.2503071059552224	[608]	[760,334,779,120]	-3	hSpCas9	negative selection	8043536
66435177	66435200	15	+	27260156	NCIH1373	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	0.16838929102151257	[206]	[257,256,270,66]	1	hSpCas9	negative selection	8043537
66436736	66436759	15	+	27260156	NCIH1373	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.7796719363933435	[486]	[1109,962,1006,175]	7	hSpCas9	negative selection	8043538
66387415	66387438	15	-	27260156	PATU8902	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-1.1377725273656345	[145]	[25,93,167,57]	-7	hSpCas9	negative selection	8100529
66436842	66436865	15	+	27260156	PATU8902	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.9217848430564859	[370]	[363,218,204,322]	-7	hSpCas9	negative selection	8100530
66387390	66387413	15	+	27260156	PATU8902	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.6197371532463636	[400]	[812,858,610,1254]	6	hSpCas9	negative selection	8100531
66435018	66435041	15	+	27260156	PATU8902	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.19157935027827816	[608]	[1048,479,875,1552]	2	hSpCas9	negative selection	8164787
66435177	66435200	15	+	27260156	PATU8902	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	0.42668044392552074	[206]	[482,210,399,455]	4	hSpCas9	negative selection	8164788
66436736	66436759	15	+	27260156	PATU8902	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.7210549881346929	[486]	[1439,1249,634,1278]	7	hSpCas9	negative selection	8164789
66387415	66387438	15	-	27260156	PANC1	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.491914450409326	[145]	[92,102,73,87]	-6	hSpCas9	negative selection	8221780
66436842	66436865	15	+	27260156	PANC1	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.9120352211419798	[370]	[222,157,155,138]	-8	hSpCas9	negative selection	8221781
66387390	66387413	15	+	27260156	PANC1	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.528229995701575	[400]	[499,512,659,336]	8	hSpCas9	negative selection	8221782
66435018	66435041	15	+	27260156	PANC1	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.036091020651505545	[608]	[431,593,734,411]	0	hSpCas9	negative selection	8286038
66435177	66435200	15	+	27260156	PANC1	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.20829096165297534	[206]	[93,256,187,104]	-3	hSpCas9	negative selection	8286039
66436736	66436759	15	+	27260156	PANC1	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.597802253609741	[486]	[596,751,516,672]	8	hSpCas9	negative selection	8286040
66387415	66387438	15	-	27260156	PANC0813	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.35898957652264074	[145]	[200,148,116,76]	-5	hSpCas9	negative selection	8343031
66436842	66436865	15	+	27260156	PANC0813	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.2984029899834851	[370]	[427,414,293,289]	-5	hSpCas9	negative selection	8343032
66387390	66387413	15	+	27260156	PANC0813	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.4417547997055259	[400]	[768,589,678,537]	7	hSpCas9	negative selection	8343033
66435018	66435041	15	+	27260156	PANC0813	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.032296041023261834	[608]	[704,1031,640,433]	0	hSpCas9	negative selection	8407289
66435177	66435200	15	+	27260156	PANC0813	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.24630506410139308	[206]	[243,124,223,228]	-4	hSpCas9	negative selection	8407290
66436736	66436759	15	+	27260156	PANC0813	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.2427439151294178	[486]	[868,518,673,662]	4	hSpCas9	negative selection	8407291
66387415	66387438	15	-	27260156	RDES	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-1.0295175412982516	[145]	[96,80,75,65]	-9	hSpCas9	negative selection	8464282
66436842	66436865	15	+	27260156	RDES	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.3289404850933266	[370]	[402,305,335,280]	-5	hSpCas9	negative selection	8464283
66387390	66387413	15	+	27260156	RDES	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.5490244216152651	[400]	[617,658,754,658]	8	hSpCas9	negative selection	8464284
66435018	66435041	15	+	27260156	RDES	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.39500579810282044	[608]	[375,549,639,594]	-6	hSpCas9	negative selection	8528540
66435177	66435200	15	+	27260156	RDES	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.06814553007565749	[206]	[188,226,230,268]	-1	hSpCas9	negative selection	8528541
66436736	66436759	15	+	27260156	RDES	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.5355356015308155	[486]	[659,650,889,1120]	8	hSpCas9	negative selection	8528542
66387415	66387438	15	-	27260156	PC3	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.39346032849870327	[145]	[34,235,75,100]	-7	hSpCas9	negative selection	8585533
66436842	66436865	15	+	27260156	PC3	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.1701187937289927	[370]	[203,288,577,367]	-4	hSpCas9	negative selection	8585534
66387390	66387413	15	+	27260156	PC3	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.19032847295981692	[400]	[266,322,850,592]	4	hSpCas9	negative selection	8585535
66435018	66435041	15	+	27260156	PC3	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.2464033811178667	[608]	[487,477,1464,784]	5	hSpCas9	negative selection	8649791
66435177	66435200	15	+	27260156	PC3	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.891079412941808	[206]	[82,126,124,113]	-9	hSpCas9	negative selection	8649792
66436736	66436759	15	+	27260156	PC3	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.265026442176004	[486]	[426,518,805,678]	6	hSpCas9	negative selection	8649793
66387415	66387438	15	-	27260156	PATU8988T	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.6793771707216054	[145]	[201,170,381,133]	9	hSpCas9	negative selection	8706784
66436842	66436865	15	+	27260156	PATU8988T	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.09196523328964898	[370]	[276,531,446,276]	1	hSpCas9	negative selection	8706785
66387390	66387413	15	+	27260156	PATU8988T	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	-0.027530414126841707	[400]	[536,360,268,350]	0	hSpCas9	negative selection	8706786
66435018	66435041	15	+	27260156	PATU8988T	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.10144499835492327	[608]	[554,656,518,466]	-2	hSpCas9	negative selection	8771042
66435177	66435200	15	+	27260156	PATU8988T	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	0.18615625571469463	[206]	[105,194,367,236]	3	hSpCas9	negative selection	8771043
66436736	66436759	15	+	27260156	PATU8988T	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.7454667824124193	[486]	[770,743,979,641]	9	hSpCas9	negative selection	8771044
66387415	66387438	15	-	27260156	T47D	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.23738323082216994	[145]	[128,114,166,168]	-5	hSpCas9	negative selection	8828035
66436842	66436865	15	+	27260156	T47D	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.16233674341547516	[370]	[419,357,349,420]	-4	hSpCas9	negative selection	8828036
66387390	66387413	15	+	27260156	T47D	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.23873658918082152	[400]	[473,492,613,629]	5	hSpCas9	negative selection	8828037
66435018	66435041	15	+	27260156	T47D	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.043704301963835956	[608]	[793,694,641,800]	0	hSpCas9	negative selection	8892293
66435177	66435200	15	+	27260156	T47D	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.2645116978238755	[206]	[225,165,149,266]	-5	hSpCas9	negative selection	8892294
66436736	66436759	15	+	27260156	T47D	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.4692339642294993	[486]	[856,707,640,949]	8	hSpCas9	negative selection	8892295
66387415	66387438	15	-	27260156	SU8686	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.2586352905402556	[145]	[93,117,144,131]	-4	hSpCas9	negative selection	8949286
66436842	66436865	15	+	27260156	SU8686	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.32901260002791166	[370]	[417,361,415,704]	5	hSpCas9	negative selection	8949287
66387390	66387413	15	+	27260156	SU8686	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.49561154481484315	[400]	[510,433,583,764]	8	hSpCas9	negative selection	8949288
66435018	66435041	15	+	27260156	SU8686	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	0.15181629388536183	[608]	[484,577,838,841]	2	hSpCas9	negative selection	9013544
66435177	66435200	15	+	27260156	SU8686	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.2349167045752063	[206]	[135,131,158,298]	-4	hSpCas9	negative selection	9013545
66436736	66436759	15	+	27260156	SU8686	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.5199833385597417	[486]	[587,543,577,1157]	8	hSpCas9	negative selection	9013546
66387415	66387438	15	-	27260156	SKES1	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.3684857029097055	[145]	[175,160,68,64]	-7	hSpCas9	negative selection	9070537
66436842	66436865	15	+	27260156	SKES1	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.1809078883725857	[370]	[409,341,310,260]	-4	hSpCas9	negative selection	9070538
66387390	66387413	15	+	27260156	SKES1	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.5037474949714007	[400]	[602,673,435,568]	8	hSpCas9	negative selection	9070539
66435018	66435041	15	+	27260156	SKES1	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.034840627890924014	[608]	[634,716,625,427]	0	hSpCas9	negative selection	9134795
66435177	66435200	15	+	27260156	SKES1	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.26102294000183845	[206]	[136,272,170,119]	-5	hSpCas9	negative selection	9134796
66436736	66436759	15	+	27260156	SKES1	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.5551162326717907	[486]	[862,533,711,734]	9	hSpCas9	negative selection	9134797
66387415	66387438	15	-	27260156	TOV112D	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.9708003678939103	[145]	[57,95,30,115]	-9	hSpCas9	negative selection	9191788
66436842	66436865	15	+	27260156	TOV112D	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.01945090745013278	[370]	[625,394,156,317]	0	hSpCas9	negative selection	9191789
66387390	66387413	15	+	27260156	TOV112D	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.459031257218447	[400]	[656,579,502,484]	8	hSpCas9	negative selection	9191790
66435018	66435041	15	+	27260156	TOV112D	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.08706125362000877	[608]	[545,891,548,389]	-2	hSpCas9	negative selection	9256046
66435177	66435200	15	+	27260156	TOV112D	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.10264716754069347	[206]	[199,202,213,158]	-2	hSpCas9	negative selection	9256047
66436736	66436759	15	+	27260156	TOV112D	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.5565399707069317	[486]	[495,801,947,626]	8	hSpCas9	negative selection	9256048
66387415	66387438	15	-	27260156	TC71	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.2616140636078894	[145]	[194,102,92,130]	-6	hSpCas9	negative selection	9313039
66436842	66436865	15	+	27260156	TC71	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.12086790652715501	[370]	[360,340,364,397]	-3	hSpCas9	negative selection	9313040
66387390	66387413	15	+	27260156	TC71	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.1489462712312965	[400]	[429,508,390,586]	4	hSpCas9	negative selection	9313041
66435018	66435041	15	+	27260156	TC71	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.09849501238688435	[608]	[645,674,463,660]	-3	hSpCas9	negative selection	9377297
66435177	66435200	15	+	27260156	TC71	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.21892026260425457	[206]	[168,208,163,223]	-5	hSpCas9	negative selection	9377298
66436736	66436759	15	+	27260156	TC71	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.2380408294975459	[486]	[633,566,607,655]	6	hSpCas9	negative selection	9377299
66387415	66387438	15	-	27260156	TC32	viability	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-1.0696025665300641	[145]	[48,53,90,74]	-9	hSpCas9	negative selection	9434290
66436842	66436865	15	+	27260156	TC32	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.339458090857301	[370]	[271,212,428,218]	-6	hSpCas9	negative selection	9434291
66387390	66387413	15	+	27260156	TC32	viability	CCCGACGGCTCTGCAGTTAACGG	MAP2K1	ENSG00000169032	0.39802732676577	[400]	[597,384,479,518]	7	hSpCas9	negative selection	9434292
66435018	66435041	15	+	27260156	TC32	viability	TTGGAACAGGACCAACTTGGAGG	MAP2K1	ENSG00000169032	-0.24171641733408222	[608]	[443,413,546,546]	-4	hSpCas9	negative selection	9498548
66435177	66435200	15	+	27260156	TC32	viability	CAATGGCGGTGTGGTGTTCAAGG	MAP2K1	ENSG00000169032	-0.10790718277409916	[206]	[219,109,217,191]	-2	hSpCas9	negative selection	9498549
66436736	66436759	15	+	27260156	TC32	viability	CTTTCTCCAGCTAATTCATCTGG	MAP2K1	ENSG00000169032	0.48817239427301345	[486]	[461,578,926,657]	8	hSpCas9	negative selection	9498550
66387415	66387438	15	-	27869803	HPAFII	viability after 27 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.32034705906788197	[607]	[333,190,NaN]	-2	hSpCas9	negative selection	9554420
66436842	66436865	15	+	27869803	HPAFII	viability after 27 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.3478798131634903	[310]	[248,173,NaN]	3	hSpCas9	negative selection	9554421
66481769	66481792	15	+	27869803	HPAFII	viability after 27 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-1.1801529904404562	[258]	[112,15,NaN]	-7	hSpCas9	negative selection	9554422
66387415	66387438	15	-	27869803	HPAFII	viability after 15 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.2255119852331402	[607]	[852,375,NaN]	-3	hSpCas9	negative selection	9636869
66436842	66436865	15	+	27869803	HPAFII	viability after 15 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.35508921659932063	[310]	[593,323,NaN]	4	hSpCas9	negative selection	9636870
66481769	66481792	15	+	27869803	HPAFII	viability after 15 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.3850082977917279	[258]	[288,165,NaN]	-4	hSpCas9	negative selection	9636871
66387415	66387438	15	-	27869803	ASPC1	viability after 36 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.2109859592789487	[1263]	[880,324,392]	2	hSpCas9	negative selection	9719318
66436842	66436865	15	+	27869803	ASPC1	viability after 36 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.1380663896494702	[835]	[381,489,140]	1	hSpCas9	negative selection	9719319
66481769	66481792	15	+	27869803	ASPC1	viability after 36 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	0.1278088947762831	[774]	[198,470,220]	1	hSpCas9	negative selection	9719320
66387415	66387438	15	-	27869803	PATU8988S	viability after 35 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.11453272897260902	[1242]	[533,549,NaN]	1	hSpCas9	negative selection	9801767
66436842	66436865	15	+	27869803	PATU8988S	viability after 35 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.05542268391703847	[680]	[235,291,NaN]	0	hSpCas9	negative selection	9801768
66481769	66481792	15	+	27869803	PATU8988S	viability after 35 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.7216476793960582	[691]	[171,165,NaN]	-6	hSpCas9	negative selection	9801769
66387415	66387438	15	-	27869803	PATU8988S	viability after 31 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	0.12820870273048302	[1242]	[447,660,NaN]	1	hSpCas9	negative selection	9884216
66436842	66436865	15	+	27869803	PATU8988S	viability after 31 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.280788364424303	[680]	[219,227,NaN]	-3	hSpCas9	negative selection	9884217
66481769	66481792	15	+	27869803	PATU8988S	viability after 31 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.6230665006035996	[691]	[172,186,NaN]	-6	hSpCas9	negative selection	9884218
66387415	66387438	15	-	27869803	HPAFII	viability after 35 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.06989541514276443	[607]	[185,413,NaN]	0	hSpCas9	negative selection	9966665
66436842	66436865	15	+	27869803	HPAFII	viability after 35 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.3166675449518031	[310]	[252,131,NaN]	2	hSpCas9	negative selection	9966666
66481769	66481792	15	+	27869803	HPAFII	viability after 35 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-0.3997867525854379	[258]	[160,29,NaN]	-2	hSpCas9	negative selection	9966667
66387415	66387438	15	-	27869803	HPAFII	viability after 31 days	CCATACTTACTCCGCAGAGCTGG	MAP2K1	ENSG00000169032	-0.3772054714139943	[607]	[300,220,NaN]	-3	hSpCas9	negative selection	10049114
66436842	66436865	15	+	27869803	HPAFII	viability after 31 days	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.36802947364317445	[310]	[230,218,NaN]	2	hSpCas9	negative selection	10049115
66481769	66481792	15	+	27869803	HPAFII	viability after 31 days	AACATCCTAGTCAACTCCCGTGG	MAP2K1	ENSG00000169032	-1.0089393567791598	[258]	[121,17,NaN]	-6	hSpCas9	negative selection	10049116
66435039	66435062	15	+	28162770	P31FUJ	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-5.385449214424856	[248]	[6]	-9	hSpCas9	negative selection	10188647
66481763	66481786	15	-	28162770	P31FUJ	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-0.4847205780539986	[180]	[151]	-4	hSpCas9	negative selection	10188648
66435117	66435140	15	+	28162770	P31FUJ	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-0.10787559251354822	[198]	[216]	-1	hSpCas9	negative selection	10188649
66444686	66444709	15	+	28162770	P31FUJ	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	0.4506339933350324	[301]	[484]	5	hSpCas9	negative selection	10188650
66481851	66481874	15	-	28162770	P31FUJ	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	-0.18175459882398592	[471]	[488]	-2	hSpCas9	negative selection	10188651
66485046	66485069	15	+	28162770	P31FUJ	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	0.5010236822212604	[275]	[458]	5	hSpCas9	negative selection	10188652
66435078	66435101	15	+	28162770	P31FUJ	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	-0.2687815015199451	[202]	[197]	-3	hSpCas9	negative selection	10188653
66436842	66436865	15	+	28162770	P31FUJ	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.22920795832469487	[558]	[769]	2	hSpCas9	negative selection	10188654
66487235	66487258	15	+	28162770	P31FUJ	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	-0.12251227371720996	[792]	[855]	-1	hSpCas9	negative selection	10188655
66435105	66435128	15	+	28162770	P31FUJ	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	1.0339843362805226	[95]	[230]	9	hSpCas9	negative selection	10188656
66435039	66435062	15	+	28162770	TF1	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10358013
66481763	66481786	15	-	28162770	TF1	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	NaN	[NaN]	[203]	1	hSpCas9	negative selection	10358014
66435117	66435140	15	+	28162770	TF1	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	NaN	[NaN]	[44]	1	hSpCas9	negative selection	10358015
66444686	66444709	15	+	28162770	TF1	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	NaN	[NaN]	[413]	1	hSpCas9	negative selection	10358016
66481851	66481874	15	-	28162770	TF1	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	NaN	[NaN]	[465]	1	hSpCas9	negative selection	10358017
66485046	66485069	15	+	28162770	TF1	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10358018
66435078	66435101	15	+	28162770	TF1	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	NaN	[NaN]	[328]	1	hSpCas9	negative selection	10358019
66436842	66436865	15	+	28162770	TF1	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	NaN	[NaN]	[512]	1	hSpCas9	negative selection	10358020
66487235	66487258	15	+	28162770	TF1	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	NaN	[NaN]	[606]	1	hSpCas9	negative selection	10358021
66435105	66435128	15	+	28162770	TF1	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10358022
66435039	66435062	15	+	28162770	SKM1	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-4.47735352663456	[62]	[4]	-9	hSpCas9	negative selection	10527379
66481763	66481786	15	-	28162770	SKM1	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-1.301169534720565	[45]	[32]	-7	hSpCas9	negative selection	10527380
66435117	66435140	15	+	28162770	SKM1	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-0.7170321384204629	[52]	[56]	-5	hSpCas9	negative selection	10527381
66444686	66444709	15	+	28162770	SKM1	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	-0.5996092766855575	[83]	[97]	-5	hSpCas9	negative selection	10527382
66481851	66481874	15	-	28162770	SKM1	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	-1.34334809944719	[121]	[84]	-7	hSpCas9	negative selection	10527383
66485046	66485069	15	+	28162770	SKM1	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	-0.8220016980220055	[92]	[92]	-6	hSpCas9	negative selection	10527384
66435078	66435101	15	+	28162770	SKM1	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	0.864498829161213	[31]	[102]	7	hSpCas9	negative selection	10527385
66436842	66436865	15	+	28162770	SKM1	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-1.7367544114034945	[114]	[60]	-8	hSpCas9	negative selection	10527386
66487235	66487258	15	+	28162770	SKM1	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	-0.30280696745186986	[186]	[267]	-3	hSpCas9	negative selection	10527387
66435105	66435128	15	+	28162770	SKM1	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	0.4003907233144425	[29]	[69]	4	hSpCas9	negative selection	10527388
66435039	66435062	15	+	28162770	SKM1	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-4.47735352663456	[62]	[4]	-9	hSpCas9	negative selection	10696745
66481763	66481786	15	-	28162770	SKM1	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-1.301169534720565	[45]	[32]	-7	hSpCas9	negative selection	10696746
66435117	66435140	15	+	28162770	SKM1	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-0.7170321384204629	[52]	[56]	-5	hSpCas9	negative selection	10696747
66444686	66444709	15	+	28162770	SKM1	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	-0.5996092766855575	[83]	[97]	-5	hSpCas9	negative selection	10696748
66481851	66481874	15	-	28162770	SKM1	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	-1.34334809944719	[121]	[84]	-7	hSpCas9	negative selection	10696749
66485046	66485069	15	+	28162770	SKM1	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	-0.8220016980220055	[92]	[92]	-6	hSpCas9	negative selection	10696750
66435078	66435101	15	+	28162770	SKM1	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	0.864498829161213	[31]	[102]	7	hSpCas9	negative selection	10696751
66436842	66436865	15	+	28162770	SKM1	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-1.7367544114034945	[114]	[60]	-8	hSpCas9	negative selection	10696752
66487235	66487258	15	+	28162770	SKM1	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	-0.30280696745186986	[186]	[267]	-3	hSpCas9	negative selection	10696753
66435105	66435128	15	+	28162770	SKM1	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	0.4003907233144425	[29]	[69]	4	hSpCas9	negative selection	10696754
66435039	66435062	15	+	28162770	PL21	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-1.0718200211239575	[226]	[46]	-6	hSpCas9	negative selection	10866111
66481763	66481786	15	-	28162770	PL21	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-0.12608861783166758	[167]	[66]	-1	hSpCas9	negative selection	10866112
66435117	66435140	15	+	28162770	PL21	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-1.061527955580568	[210]	[43]	-6	hSpCas9	negative selection	10866113
66444686	66444709	15	+	28162770	PL21	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	0.1492156793266478	[345]	[166]	1	hSpCas9	negative selection	10866114
66481851	66481874	15	-	28162770	PL21	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	-0.19761989335768804	[497]	[188]	-1	hSpCas9	negative selection	10866115
66485046	66485069	15	+	28162770	PL21	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	0.12689063245868148	[302]	[143]	1	hSpCas9	negative selection	10866116
66435078	66435101	15	+	28162770	PL21	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	0.6510541500967605	[138]	[94]	5	hSpCas9	negative selection	10866117
66436842	66436865	15	+	28162770	PL21	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.1251396898976802	[430]	[171]	-1	hSpCas9	negative selection	10866118
66487235	66487258	15	+	28162770	PL21	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	-0.2404329768966611	[569]	[209]	-2	hSpCas9	negative selection	10866119
66435105	66435128	15	+	28162770	PL21	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-1.6692762757005355	[94]	[12]	-8	hSpCas9	negative selection	10866120
66435039	66435062	15	+	28162770	P31FUJ	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-5.385449214424856	[248]	[6]	-9	hSpCas9	negative selection	11035477
66481763	66481786	15	-	28162770	P31FUJ	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-0.4847205780539986	[180]	[151]	-4	hSpCas9	negative selection	11035478
66435117	66435140	15	+	28162770	P31FUJ	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-0.10787559251354822	[198]	[216]	-1	hSpCas9	negative selection	11035479
66444686	66444709	15	+	28162770	P31FUJ	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	0.4506339933350324	[301]	[484]	5	hSpCas9	negative selection	11035480
66481851	66481874	15	-	28162770	P31FUJ	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	-0.18175459882398592	[471]	[488]	-2	hSpCas9	negative selection	11035481
66485046	66485069	15	+	28162770	P31FUJ	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	0.5010236822212604	[275]	[458]	5	hSpCas9	negative selection	11035482
66435078	66435101	15	+	28162770	P31FUJ	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	-0.2687815015199451	[202]	[197]	-3	hSpCas9	negative selection	11035483
66436842	66436865	15	+	28162770	P31FUJ	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.22920795832469487	[558]	[769]	2	hSpCas9	negative selection	11035484
66487235	66487258	15	+	28162770	P31FUJ	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	-0.12251227371720996	[792]	[855]	-1	hSpCas9	negative selection	11035485
66435105	66435128	15	+	28162770	P31FUJ	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	1.0339843362805226	[95]	[230]	9	hSpCas9	negative selection	11035486
66435039	66435062	15	+	28162770	OCIAML5	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-7.7224312904474015	[116]	[0]	-9	hSpCas9	negative selection	11204843
66481763	66481786	15	-	28162770	OCIAML5	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-0.23660198174549685	[155]	[238]	-2	hSpCas9	negative selection	11204844
66435117	66435140	15	+	28162770	OCIAML5	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	0.2933638686575669	[65]	[145]	2	hSpCas9	negative selection	11204845
66444686	66444709	15	+	28162770	OCIAML5	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	0.6768618949428311	[174]	[504]	6	hSpCas9	negative selection	11204846
66481851	66481874	15	-	28162770	OCIAML5	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	0.2745450626681778	[277]	[606]	2	hSpCas9	negative selection	11204847
66485046	66485069	15	+	28162770	OCIAML5	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	0.27192214641145634	[116]	[254]	2	hSpCas9	negative selection	11204848
66435078	66435101	15	+	28162770	OCIAML5	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	0.7259598826467827	[138]	[414]	6	hSpCas9	negative selection	11204849
66436842	66436865	15	+	28162770	OCIAML5	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.05859085466744074	[407]	[766]	0	hSpCas9	negative selection	11204850
66487235	66487258	15	+	28162770	OCIAML5	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	0.6212649312742298	[384]	[1068]	5	hSpCas9	negative selection	11204851
66435105	66435128	15	+	28162770	OCIAML5	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	0.3305248424144759	[62]	[142]	3	hSpCas9	negative selection	11204852
66435039	66435062	15	+	28162770	EOL1	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-2.318524902605588	[444]	[46]	-8	hSpCas9	negative selection	11374209
66481763	66481786	15	-	28162770	EOL1	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	0.12771072142693002	[204]	[117]	1	hSpCas9	negative selection	11374210
66435117	66435140	15	+	28162770	EOL1	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-0.07981742099086724	[330]	[164]	0	hSpCas9	negative selection	11374211
66444686	66444709	15	+	28162770	EOL1	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	0.1030486671926607	[614]	[347]	0	hSpCas9	negative selection	11374212
66481851	66481874	15	-	28162770	EOL1	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	-0.0842581258048063	[985]	[489]	0	hSpCas9	negative selection	11374213
66485046	66485069	15	+	28162770	EOL1	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	0.09447277301284707	[559]	[314]	0	hSpCas9	negative selection	11374214
66435078	66435101	15	+	28162770	EOL1	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	-0.5641994138913186	[173]	[61]	-4	hSpCas9	negative selection	11374215
66436842	66436865	15	+	28162770	EOL1	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.12158461863008829	[573]	[328]	1	hSpCas9	negative selection	11374216
66487235	66487258	15	+	28162770	EOL1	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	0.030589408980859156	[943]	[507]	0	hSpCas9	negative selection	11374217
66435105	66435128	15	+	28162770	EOL1	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-0.11647949668952018	[106]	[51]	-1	hSpCas9	negative selection	11374218
66435039	66435062	15	+	28162770	MOLM13	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-4.3134703319800805	[329]	[11]	-9	hSpCas9	negative selection	11543575
66481763	66481786	15	-	28162770	MOLM13	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-0.41289746012804057	[266]	[144]	-2	hSpCas9	negative selection	11543576
66435117	66435140	15	+	28162770	MOLM13	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-0.8587611235851867	[305]	[121]	-5	hSpCas9	negative selection	11543577
66444686	66444709	15	+	28162770	MOLM13	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	0.9314567747510814	[474]	[654]	7	hSpCas9	negative selection	11543578
66481851	66481874	15	-	28162770	MOLM13	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	0.592530754357464	[675]	[736]	4	hSpCas9	negative selection	11543579
66485046	66485069	15	+	28162770	MOLM13	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	0.9471354279328488	[400]	[558]	7	hSpCas9	negative selection	11543580
66435078	66435101	15	+	28162770	MOLM13	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	-0.014974931557841187	[224]	[160]	0	hSpCas9	negative selection	11543581
66436842	66436865	15	+	28162770	MOLM13	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.5632674296218372	[555]	[593]	4	hSpCas9	negative selection	11543582
66487235	66487258	15	+	28162770	MOLM13	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	0.33550066941272316	[900]	[821]	2	hSpCas9	negative selection	11543583
66435105	66435128	15	+	28162770	MOLM13	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-0.9471481177342649	[119]	[44]	-5	hSpCas9	negative selection	11543584
66435039	66435062	15	+	28162770	HEL	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-2.0437616951828614	[308]	[47]	-8	hSpCas9	negative selection	11712941
66481763	66481786	15	-	28162770	HEL	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-0.6127619011480294	[190]	[79]	-4	hSpCas9	negative selection	11712942
66435117	66435140	15	+	28162770	HEL	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-0.1703297412516407	[252]	[143]	-1	hSpCas9	negative selection	11712943
66444686	66444709	15	+	28162770	HEL	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	0.37002936512878193	[388]	[321]	3	hSpCas9	negative selection	11712944
66481851	66481874	15	-	28162770	HEL	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	-0.5744358800650716	[643]	[276]	-4	hSpCas9	negative selection	11712945
66485046	66485069	15	+	28162770	HEL	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	0.17295112860770578	[366]	[264]	1	hSpCas9	negative selection	11712946
66435078	66435101	15	+	28162770	HEL	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	-0.07408911659477313	[165]	[100]	0	hSpCas9	negative selection	11712947
66436842	66436865	15	+	28162770	HEL	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.22852785387744023	[449]	[245]	-2	hSpCas9	negative selection	11712948
66487235	66487258	15	+	28162770	HEL	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	-0.4986170172451845	[749]	[339]	-3	hSpCas9	negative selection	11712949
66435105	66435128	15	+	28162770	HEL	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-1.3928850777303645	[81]	[19]	-7	hSpCas9	negative selection	11712950
66435039	66435062	15	+	28162770	MV411	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-3.0993652127436166	[233]	[22]	-9	hSpCas9	negative selection	11882307
66481763	66481786	15	-	28162770	MV411	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	0.7786287950629508	[163]	[236]	7	hSpCas9	negative selection	11882308
66435117	66435140	15	+	28162770	MV411	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-0.614365155297205	[188]	[103]	-4	hSpCas9	negative selection	11882309
66444686	66444709	15	+	28162770	MV411	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	0.23572413021898497	[370]	[367]	2	hSpCas9	negative selection	11882310
66481851	66481874	15	-	28162770	MV411	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	0.06329869012076217	[458]	[403]	0	hSpCas9	negative selection	11882311
66485046	66485069	15	+	28162770	MV411	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	1.108784010996745	[250]	[455]	8	hSpCas9	negative selection	11882312
66435078	66435101	15	+	28162770	MV411	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	1.9191116846972625	[112]	[359]	9	hSpCas9	negative selection	11882313
66436842	66436865	15	+	28162770	MV411	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.8271057518344185	[363]	[543]	7	hSpCas9	negative selection	11882314
66487235	66487258	15	+	28162770	MV411	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	0.5117436138526177	[566]	[680]	4	hSpCas9	negative selection	11882315
66435105	66435128	15	+	28162770	MV411	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-0.30649805431775623	[68]	[46]	-2	hSpCas9	negative selection	11882316
66435039	66435062	15	+	28162770	MONOMAC1	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-0.7738254163350097	[175]	[117]	-6	hSpCas9	negative selection	12051673
66481763	66481786	15	-	28162770	MONOMAC1	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	0.6285674474529079	[100]	[178]	6	hSpCas9	negative selection	12051674
66435117	66435140	15	+	28162770	MONOMAC1	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	0.16422939577830944	[122]	[157]	1	hSpCas9	negative selection	12051675
66444686	66444709	15	+	28162770	MONOMAC1	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	0.9143620777763031	[217]	[470]	8	hSpCas9	negative selection	12051676
66481851	66481874	15	-	28162770	MONOMAC1	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	0.4060379490461421	[342]	[520]	4	hSpCas9	negative selection	12051677
66485046	66485069	15	+	28162770	MONOMAC1	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	0.32215788351058217	[186]	[267]	3	hSpCas9	negative selection	12051678
66435078	66435101	15	+	28162770	MONOMAC1	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	0.1414877583585034	[120]	[152]	1	hSpCas9	negative selection	12051679
66436842	66436865	15	+	28162770	MONOMAC1	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	0.1602243209400892	[241]	[309]	1	hSpCas9	negative selection	12051680
66487235	66487258	15	+	28162770	MONOMAC1	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	0.501351714995957	[378]	[614]	5	hSpCas9	negative selection	12051681
66435105	66435128	15	+	28162770	MONOMAC1	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-0.5111454374876168	[45]	[36]	-4	hSpCas9	negative selection	12051682
66435039	66435062	15	+	28162770	OCIAML2	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-7.930061443879459	[43]	[0]	-9	hSpCas9	negative selection	12221039
66481763	66481786	15	-	28162770	OCIAML2	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-5.0951206901499555	[36]	[5]	-9	hSpCas9	negative selection	12221040
66435117	66435140	15	+	28162770	OCIAML2	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	-3.156521234814098	[36]	[22]	-9	hSpCas9	negative selection	12221041
66444686	66444709	15	+	28162770	OCIAML2	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	-3.760136442437146	[65]	[26]	-9	hSpCas9	negative selection	12221042
66481851	66481874	15	-	28162770	OCIAML2	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	-2.430552385866826	[70]	[72]	-8	hSpCas9	negative selection	12221043
66485046	66485069	15	+	28162770	OCIAML2	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	-4.196454861803167	[42]	[12]	-9	hSpCas9	negative selection	12221044
66435078	66435101	15	+	28162770	OCIAML2	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	-1.7825738315569013	[35]	[57]	-8	hSpCas9	negative selection	12221045
66436842	66436865	15	+	28162770	OCIAML2	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-3.068531381670816	[55]	[36]	-9	hSpCas9	negative selection	12221046
66487235	66487258	15	+	28162770	OCIAML2	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	-1.7851404485670406	[96]	[155]	-8	hSpCas9	negative selection	12221047
66435105	66435128	15	+	28162770	OCIAML2	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-2.6930222465786096	[13]	[11]	-9	hSpCas9	negative selection	12221048
66435039	66435062	15	+	28162770	OCIAML3	viability	GGCCTTGCAGAAGAAGCTGGAGG	MAP2K1	ENSG00000169032	-1.7668442371863786	[61]	[54]	-8	hSpCas9	negative selection	12390405
66481763	66481786	15	-	28162770	OCIAML3	viability	GAGTTGACTAGGATGTTGGAGGG	MAP2K1	ENSG00000169032	-1.821418136427236	[47]	[40]	-8	hSpCas9	negative selection	12390406
66435117	66435140	15	+	28162770	OCIAML3	viability	GCAGAAGGTGGGAGAACTGAAGG	MAP2K1	ENSG00000169032	0.5384426556994866	[38]	[170]	5	hSpCas9	negative selection	12390407
66444686	66444709	15	+	28162770	OCIAML3	viability	AAGCACAAGATCATGCACAGAGG	MAP2K1	ENSG00000169032	-0.6026207706288713	[83]	[166]	-4	hSpCas9	negative selection	12390408
66481851	66481874	15	-	28162770	OCIAML3	viability	GTAGGACCTTGTGCCCACGAAGG	MAP2K1	ENSG00000169032	-0.5072028127868907	[128]	[273]	-4	hSpCas9	negative selection	12390409
66485046	66485069	15	+	28162770	OCIAML3	viability	ACTGTCTCTGGTAGAGATGGCGG	MAP2K1	ENSG00000169032	-1.6207249786999427	[108]	[106]	-8	hSpCas9	negative selection	12390410
66435078	66435101	15	+	28162770	OCIAML3	viability	GCAGCAGCGAAAGCGCCTTGAGG	MAP2K1	ENSG00000169032	-0.5940076403241632	[33]	[67]	-4	hSpCas9	negative selection	12390411
66436842	66436865	15	+	28162770	OCIAML3	viability	TATGGTGCGTTCTACAGCGATGG	MAP2K1	ENSG00000169032	-0.7742156150283362	[131]	[232]	-5	hSpCas9	negative selection	12390412
66487235	66487258	15	+	28162770	OCIAML3	viability	AATGGACAGCCGACCTCCCATGG	MAP2K1	ENSG00000169032	-0.8115990753967898	[174]	[300]	-6	hSpCas9	negative selection	12390413
66435105	66435128	15	+	28162770	OCIAML3	viability	TCTTACCCAGAAGCAGAAGGTGG	MAP2K1	ENSG00000169032	-0.34889514248763154	[26]	[63]	-3	hSpCas9	negative selection	12390414