Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5605
• Symbol: MAP2K2
• Description: mitogen-activated protein kinase kinase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/MAP2K2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
4123793	4123816	19	-	26472758	Jiyoye	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	0.682035222736457	[80]	[97]	5	hSpCas9	negative selection	95886
4117481	4117504	19	-	26472758	Jiyoye	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	-0.6992139630861035	[210]	[97]	-5	hSpCas9	negative selection	95887
4101228	4101251	19	-	26472758	Jiyoye	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	0.5634310794770807	[270]	[301]	4	hSpCas9	negative selection	95888
4099316	4099339	19	+	26472758	Jiyoye	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	0.8617412449713547	[53]	[73]	6	hSpCas9	negative selection	95889
4117418	4117441	19	-	26472758	Jiyoye	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	0.3903015629414772	[85]	[84]	3	hSpCas9	negative selection	95890
4102391	4102414	19	-	26472758	Jiyoye	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	5.162062883669342	[0]	[26]	9	hSpCas9	negative selection	95891
4097314	4097337	19	-	26472758	Jiyoye	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	-1.2109539831504823	[131]	[42]	-7	hSpCas9	negative selection	95892
4097297	4097320	19	+	26472758	Jiyoye	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	-0.8518008077535671	[212]	[88]	-5	hSpCas9	negative selection	95893
4094479	4094502	19	-	26472758	Jiyoye	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	-0.2217830230419665	[282]	[182]	-1	hSpCas9	negative selection	95894
4117563	4117586	19	-	26472758	Jiyoye	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.5020345678473146	[102]	[109]	4	hSpCas9	negative selection	95895
4123793	4123816	19	-	26472758	KBM7	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	-0.03320441967310361	[558,442]	[188,263]	0	hSpCas9	negative selection	287004
4117481	4117504	19	-	26472758	KBM7	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.37055417467789525	[581,453]	[341,285]	4	hSpCas9	negative selection	287005
4101228	4101251	19	-	26472758	KBM7	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	1.1613188964005752	[1105,794]	[1030,948]	9	hSpCas9	negative selection	287006
4099316	4099339	19	+	26472758	KBM7	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	0.5303491293521211	[164,161]	[130,93]	6	hSpCas9	negative selection	287007
4117418	4117441	19	-	26472758	KBM7	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	0.7495232643154962	[418,236]	[277,230]	7	hSpCas9	negative selection	287008
4102391	4102414	19	-	26472758	KBM7	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	0.4677373489655914	[131,94]	[111,37]	5	hSpCas9	negative selection	287009
4097314	4097337	19	-	26472758	KBM7	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	1.3563362158090555	[188,226]	[301,210]	9	hSpCas9	negative selection	287010
4097297	4097320	19	+	26472758	KBM7	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	0.0029508471288391402	[868,374]	[299,266]	0	hSpCas9	negative selection	287011
4094479	4094502	19	-	26472758	KBM7	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	0.2858908426807233	[776,661]	[352,462]	3	hSpCas9	negative selection	287012
4117563	4117586	19	-	26472758	KBM7	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.4270189607380248	[455,539]	[402,243]	4	hSpCas9	negative selection	287013
4123793	4123816	19	-	26472758	Raji	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	0.15547782357464449	[235]	[60]	1	hSpCas9	negative selection	478122
4117481	4117504	19	-	26472758	Raji	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.22286075279353545	[287]	[77]	2	hSpCas9	negative selection	478123
4101228	4101251	19	-	26472758	Raji	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	0.9281807203432766	[350]	[154]	8	hSpCas9	negative selection	478124
4099316	4099339	19	+	26472758	Raji	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	0.48494632923378056	[116]	[37]	4	hSpCas9	negative selection	478125
4117418	4117441	19	-	26472758	Raji	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	1.6479519167363024	[98]	[71]	9	hSpCas9	negative selection	478126
4102391	4102414	19	-	26472758	Raji	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	-0.6088234986258096	[45]	[6]	-5	hSpCas9	negative selection	478127
4097314	4097337	19	-	26472758	Raji	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	0.5756630559294227	[132]	[45]	5	hSpCas9	negative selection	478128
4097297	4097320	19	+	26472758	Raji	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	-0.0009160799732893521	[400]	[92]	0	hSpCas9	negative selection	478129
4094479	4094502	19	-	26472758	Raji	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	-0.09425032579605111	[252]	[54]	-1	hSpCas9	negative selection	478130
4117563	4117586	19	-	26472758	Raji	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.011260961125019675	[303]	[69]	0	hSpCas9	negative selection	478131
4123793	4123816	19	-	26472758	K562	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	-0.4254326706412224	[454]	[285]	-3	hSpCas9	negative selection	669240
4117481	4117504	19	-	26472758	K562	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.7272988727263421	[404]	[565]	6	hSpCas9	negative selection	669241
4101228	4101251	19	-	26472758	K562	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	0.19616355905922567	[759]	[734]	1	hSpCas9	negative selection	669242
4099316	4099339	19	+	26472758	K562	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	-1.0581440423539843	[221]	[89]	-5	hSpCas9	negative selection	669243
4117418	4117441	19	-	26472758	K562	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	-0.6743309518103882	[396]	[209]	-4	hSpCas9	negative selection	669244
4102391	4102414	19	-	26472758	K562	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	-6.355494114520679	[96]	[0]	-9	hSpCas9	negative selection	669245
4097314	4097337	19	-	26472758	K562	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	1.0401483246044239	[177]	[308]	8	hSpCas9	negative selection	669246
4097297	4097320	19	+	26472758	K562	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	0.3281870853590446	[367]	[389]	2	hSpCas9	negative selection	669247
4094479	4094502	19	-	26472758	K562	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	-0.5250275304669246	[553]	[324]	-3	hSpCas9	negative selection	669248
4117563	4117586	19	-	26472758	K562	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.05105535494153102	[573]	[501]	0	hSpCas9	negative selection	669249
4090688	4090711	19	-	26627737	DLD1	viability	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	0.012462046418917239	[914]	[420,240,212]	0	hSpCas9	negative selection	804817
4097278	4097301	19	-	26627737	DLD1	viability	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	0.7483971600927455	[1155]	[649,601,573]	7	hSpCas9	negative selection	804833
4099223	4099246	19	-	26627737	DLD1	viability	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	-0.0840428518355747	[858]	[463,159,147]	-1	hSpCas9	negative selection	804835
4117559	4117582	19	-	26627737	DLD1	viability	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	-0.359438814701434	[248]	[109,33,39]	-4	hSpCas9	negative selection	804853
4117563	4117586	19	-	26627737	DLD1	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.55001743195879	[800]	[274,374,438]	5	hSpCas9	negative selection	804854
4090688	4090711	19	-	26627737	GBM cells	viability after 5 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.3315300303464064	[568]	[250,233]	-5	hSpCas9	negative selection	887132
4097278	4097301	19	-	26627737	GBM cells	viability after 5 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	0.09999578997672143	[681]	[368,414]	1	hSpCas9	negative selection	887148
4099223	4099246	19	-	26627737	GBM cells	viability after 5 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.5329047115342065	[269]	[222,195]	7	hSpCas9	negative selection	887150
4117559	4117582	19	-	26627737	GBM cells	viability after 5 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	0.6583343198795876	[152]	[127,130]	8	hSpCas9	negative selection	887168
4117563	4117586	19	-	26627737	GBM cells	viability after 5 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.20025562851764023	[606]	[381,365]	3	hSpCas9	negative selection	887169
4090688	4090711	19	-	26627737	GBM cells	viability after 13 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.6258482455816726	[568]	[268,143]	-6	hSpCas9	negative selection	969447
4097278	4097301	19	-	26627737	GBM cells	viability after 13 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	0.07264683759318058	[681]	[408,372]	0	hSpCas9	negative selection	969463
4099223	4099246	19	-	26627737	GBM cells	viability after 13 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.6282331929943977	[269]	[269,190]	7	hSpCas9	negative selection	969465
4117559	4117582	19	-	26627737	GBM cells	viability after 13 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	-0.8047592840866047	[152]	[57,38]	-7	hSpCas9	negative selection	969483
4117563	4117586	19	-	26627737	GBM cells	viability after 13 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.23725591156764403	[606]	[476,315]	3	hSpCas9	negative selection	969484
4090688	4090711	19	-	26627737	GBM cells	viability after 21 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.7873405156052686	[568]	[199,159]	-6	hSpCas9	negative selection	1051762
4097278	4097301	19	-	26627737	GBM cells	viability after 21 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	-0.15738986176535907	[681]	[326,336]	-1	hSpCas9	negative selection	1051778
4099223	4099246	19	-	26627737	GBM cells	viability after 21 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.1598941271100632	[269]	[154,171]	1	hSpCas9	negative selection	1051780
4117559	4117582	19	-	26627737	GBM cells	viability after 21 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	-1.7611367251270538	[152]	[23,24]	-8	hSpCas9	negative selection	1051798
4117563	4117586	19	-	26627737	GBM cells	viability after 21 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.1353790561458168	[606]	[329,272]	-1	hSpCas9	negative selection	1051799
4090688	4090711	19	-	26627737	RPE1	viability after 9 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-1.2812737410085728	[1534]	[181,217]	-7	hSpCas9	negative selection	1134077
4097278	4097301	19	-	26627737	RPE1	viability after 9 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	-0.27292070126985757	[3704]	[866,1079]	-2	hSpCas9	negative selection	1134093
4099223	4099246	19	-	26627737	RPE1	viability after 9 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.4782567878325333	[965]	[505,311]	3	hSpCas9	negative selection	1134095
4117559	4117582	19	-	26627737	RPE1	viability after 9 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	1.9456595886580266	[151]	[305,24]	8	hSpCas9	negative selection	1134113
4117563	4117586	19	-	26627737	RPE1	viability after 9 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.12096605964361129	[2237]	[850,646]	0	hSpCas9	negative selection	1134114
4090688	4090711	19	-	26627737	RPE1	viability after 12 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-1.4059483936889263	[1534]	[210,96]	-7	hSpCas9	negative selection	1216392
4097278	4097301	19	-	26627737	RPE1	viability after 12 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	-0.7807305411370171	[3704]	[558,600]	-5	hSpCas9	negative selection	1216408
4099223	4099246	19	-	26627737	RPE1	viability after 12 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.6056277797149268	[965]	[544,235]	4	hSpCas9	negative selection	1216410
4117559	4117582	19	-	26627737	RPE1	viability after 12 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	2.075646407289272	[151]	[193,148]	9	hSpCas9	negative selection	1216428
4117563	4117586	19	-	26627737	RPE1	viability after 12 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.5213338398756988	[2237]	[930,790]	3	hSpCas9	negative selection	1216429
4090688	4090711	19	-	26627737	RPE1	viability after 15 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-1.2468596347725103	[1534]	[184,180]	-7	hSpCas9	negative selection	1298707
4097278	4097301	19	-	26627737	RPE1	viability after 15 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	-0.8793208796306515	[3704]	[639,501]	-5	hSpCas9	negative selection	1298723
4099223	4099246	19	-	26627737	RPE1	viability after 15 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.8243887557445986	[965]	[630,341]	5	hSpCas9	negative selection	1298725
4117559	4117582	19	-	26627737	RPE1	viability after 15 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	2.437909441185421	[151]	[261,204]	9	hSpCas9	negative selection	1298743
4117563	4117586	19	-	26627737	RPE1	viability after 15 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.36403829566773593	[2237]	[910,721]	2	hSpCas9	negative selection	1298744
4090688	4090711	19	-	26627737	RPE1	viability after 18 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-1.8632651093068349	[1534]	[167,55]	-8	hSpCas9	negative selection	1381022
4097278	4097301	19	-	26627737	RPE1	viability after 18 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	-0.7065045410094162	[3704]	[691,527]	-4	hSpCas9	negative selection	1381038
4099223	4099246	19	-	26627737	RPE1	viability after 18 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.40430088750762	[965]	[359,328]	2	hSpCas9	negative selection	1381040
4117559	4117582	19	-	26627737	RPE1	viability after 18 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	2.732668407721573	[151]	[247,298]	9	hSpCas9	negative selection	1381058
4117563	4117586	19	-	26627737	RPE1	viability after 18 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.6103858670554654	[2237]	[981,857]	4	hSpCas9	negative selection	1381059
4090688	4090711	19	-	26627737	HeLa	viability after 8 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	0.06974022673792868	[727]	[274,380,328]	0	hSpCas9	negative selection	1463337
4097278	4097301	19	-	26627737	HeLa	viability after 8 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	-0.8039495497512932	[2005]	[792,398,380]	-7	hSpCas9	negative selection	1463353
4099223	4099246	19	-	26627737	HeLa	viability after 8 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	1.034042375544078	[416]	[385,539,203]	7	hSpCas9	negative selection	1463355
4117559	4117582	19	-	26627737	HeLa	viability after 8 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	-0.3826271096833812	[274]	[98,86,90]	-4	hSpCas9	negative selection	1463373
4117563	4117586	19	-	26627737	HeLa	viability after 8 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.43451949042283877	[1016]	[330,396,259]	-4	hSpCas9	negative selection	1463374
4090688	4090711	19	-	26627737	HeLa	viability after 12 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	0.3354387714529329	[727]	[392,409,332]	3	hSpCas9	negative selection	1545652
4097278	4097301	19	-	26627737	HeLa	viability after 12 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	-0.5816980703334549	[2005]	[387,477,798]	-5	hSpCas9	negative selection	1545668
4099223	4099246	19	-	26627737	HeLa	viability after 12 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	1.2450474478746336	[416]	[563,388,278]	8	hSpCas9	negative selection	1545670
4117559	4117582	19	-	26627737	HeLa	viability after 12 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	-0.5351670200937128	[274]	[95,66,73]	-5	hSpCas9	negative selection	1545688
4117563	4117586	19	-	26627737	HeLa	viability after 12 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.180349754383077	[1016]	[577,501,348]	1	hSpCas9	negative selection	1545689
4090688	4090711	19	-	26627737	HeLa	viability after 15 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.23903397279424854	[727]	[185,246,326]	-2	hSpCas9	negative selection	1627967
4097278	4097301	19	-	26627737	HeLa	viability after 15 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	-0.9490203564170301	[2005]	[260,334,695]	-7	hSpCas9	negative selection	1627983
4099223	4099246	19	-	26627737	HeLa	viability after 15 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.641014906670452	[416]	[217,212,371]	5	hSpCas9	negative selection	1627985
4117559	4117582	19	-	26627737	HeLa	viability after 15 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	0.7480077069067376	[274]	[483,11,53]	6	hSpCas9	negative selection	1628003
4117563	4117586	19	-	26627737	HeLa	viability after 15 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.01805281534445169	[1016]	[400,581,262]	0	hSpCas9	negative selection	1628004
4090688	4090711	19	-	26627737	HeLa	viability after 18 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.18573837037972607	[727]	[129,220,326]	-1	hSpCas9	negative selection	1710282
4097278	4097301	19	-	26627737	HeLa	viability after 18 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	-0.9575200064710343	[2005]	[172,273,695]	-7	hSpCas9	negative selection	1710298
4099223	4099246	19	-	26627737	HeLa	viability after 18 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.6377430375970123	[416]	[142,178,371]	5	hSpCas9	negative selection	1710300
4117559	4117582	19	-	26627737	HeLa	viability after 18 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	0.7229500606669184	[274]	[319,7,53]	5	hSpCas9	negative selection	1710318
4117563	4117586	19	-	26627737	HeLa	viability after 18 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.010271157950667131	[1016]	[274,468,262]	0	hSpCas9	negative selection	1710319
4090688	4090711	19	-	26627737	HCT116	viability after 6 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.4291954495580449	[1583]	[289,126]	-2	hSpCas9	negative selection	1792597
4097278	4097301	19	-	26627737	HCT116	viability after 6 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	-0.5514718850863503	[2308]	[315,209]	-3	hSpCas9	negative selection	1792613
4099223	4099246	19	-	26627737	HCT116	viability after 6 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.14584791152733967	[1290]	[424,113]	0	hSpCas9	negative selection	1792615
4117559	4117582	19	-	26627737	HCT116	viability after 6 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	0.8314113060086998	[764]	[213,213]	4	hSpCas9	negative selection	1792633
4117563	4117586	19	-	26627737	HCT116	viability after 6 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.5822199064547968	[1249]	[270,306]	3	hSpCas9	negative selection	1792634
4090688	4090711	19	-	26627737	HCT116	viability after 8 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.7525233584977593	[763]	[193,333,220]	-7	hSpCas9	negative selection	1874912
4097278	4097301	19	-	26627737	HCT116	viability after 8 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	0.6642453338001952	[621]	[616,571,442]	6	hSpCas9	negative selection	1874928
4099223	4099246	19	-	26627737	HCT116	viability after 8 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	1.2123545471787491	[281]	[403,401,275]	8	hSpCas9	negative selection	1874930
4117559	4117582	19	-	26627737	HCT116	viability after 8 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	0.5591166982635895	[158]	[152,48,184]	5	hSpCas9	negative selection	1874948
4117563	4117586	19	-	26627737	HCT116	viability after 8 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.06893541909668799	[805]	[484,336,448]	0	hSpCas9	negative selection	1874949
4090688	4090711	19	-	26627737	HCT116	viability after 9 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.40825858409057303	[1583]	[330,308]	-3	hSpCas9	negative selection	1957227
4097278	4097301	19	-	26627737	HCT116	viability after 9 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	-0.5684980087003204	[2308]	[503,345]	-4	hSpCas9	negative selection	1957243
4099223	4099246	19	-	26627737	HCT116	viability after 9 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	-0.41538870788312177	[1290]	[396,148]	-3	hSpCas9	negative selection	1957245
4117559	4117582	19	-	26627737	HCT116	viability after 9 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	0.7176044216897723	[764]	[393,289]	5	hSpCas9	negative selection	1957263
4117563	4117586	19	-	26627737	HCT116	viability after 9 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.48098934982483965	[1249]	[514,426]	3	hSpCas9	negative selection	1957264
4090688	4090711	19	-	26627737	HCT116	viability after 12 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.9636747098398466	[763]	[171,222,225]	-8	hSpCas9	negative selection	2039542
4097278	4097301	19	-	26627737	HCT116	viability after 12 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	0.5208106833687525	[621]	[477,543,385]	5	hSpCas9	negative selection	2039558
4099223	4099246	19	-	26627737	HCT116	viability after 12 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	1.2093365498807263	[281]	[224,491,324]	8	hSpCas9	negative selection	2039560
4117559	4117582	19	-	26627737	HCT116	viability after 12 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	0.13581248434329174	[158]	[35,160,84]	1	hSpCas9	negative selection	2039578
4117563	4117586	19	-	26627737	HCT116	viability after 12 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.044553173810008895	[805]	[472,378,453]	0	hSpCas9	negative selection	2039579
4090688	4090711	19	-	26627737	HCT116	viability after 15 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.676224776279127	[763]	[215,192,405]	-6	hSpCas9	negative selection	2121857
4097278	4097301	19	-	26627737	HCT116	viability after 15 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	0.8355548621456292	[621]	[721,590,609]	7	hSpCas9	negative selection	2121873
4099223	4099246	19	-	26627737	HCT116	viability after 15 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	1.4283488569426108	[281]	[428,625,253]	9	hSpCas9	negative selection	2121875
4117559	4117582	19	-	26627737	HCT116	viability after 15 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	0.8589529077238671	[158]	[118,191,179]	7	hSpCas9	negative selection	2121893
4117563	4117586	19	-	26627737	HCT116	viability after 15 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.0969813357555489	[805]	[774,309,434]	1	hSpCas9	negative selection	2121894
4090688	4090711	19	-	26627737	HCT116	viability after 18 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.6706220890214619	[763]	[210,198,290]	-6	hSpCas9	negative selection	2204172
4097278	4097301	19	-	26627737	HCT116	viability after 18 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	0.7513272390997765	[621]	[468,397,665]	6	hSpCas9	negative selection	2204188
4099223	4099246	19	-	26627737	HCT116	viability after 18 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	1.526999664044278	[281]	[382,496,286]	9	hSpCas9	negative selection	2204190
4117559	4117582	19	-	26627737	HCT116	viability after 18 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	0.8272338386853293	[158]	[31,231,138]	6	hSpCas9	negative selection	2204208
4117563	4117586	19	-	26627737	HCT116	viability after 18 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.12134273225792236	[805]	[453,304,524]	1	hSpCas9	negative selection	2204209
4117418	4117441	19	-	24336569	HL60	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	-0.10204497805134821	[352]	[695]	-1	hSpCas9	negative selection	2275758
4117480	4117503	19	-	24336569	HL60	viability	AGGATCTCAGAGCTGGGCGCGGG	MAP2K2	ENSG00000126934	-0.019285109369009318	[578]	[1208]	0	hSpCas9	negative selection	2275759
4117486	4117509	19	-	24336569	HL60	viability	TTCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	0.5560933510398169	[1211]	[3770]	5	hSpCas9	negative selection	2275760
4117559	4117582	19	-	24336569	HL60	viability	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	0.2959935629718056	[631]	[1641]	3	hSpCas9	negative selection	2275761
4117616	4117639	19	-	24336569	HL60	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.9325700084908346	[1022]	[4131]	7	hSpCas9	negative selection	2275762
4123780	4123803	19	+	24336569	HL60	viability	TCACTCGGAGGCGCCCTCGCTGG	MAP2K2	ENSG00000126934	0.04284056656839241	[1127]	[2458]	0	hSpCas9	negative selection	2275763
4123785	4123808	19	+	24336569	HL60	viability	CGGAGGCGCCCTCGCTGGTAGGG	MAP2K2	ENSG00000126934	0.01742156388156102	[295]	[633]	0	hSpCas9	negative selection	2275764
4123835	4123858	19	+	24336569	HL60	viability	ATGGTGAGCGCCGGCAGCACCGG	MAP2K2	ENSG00000126934	-1.2669096874075865	[1284]	[1129]	-8	hSpCas9	negative selection	2275765
4123845	4123868	19	-	24336569	HL60	viability	CCGGAGGAAGCCGGTGCTGCCGG	MAP2K2	ENSG00000126934	0.8655449965845896	[1122]	[4329]	7	hSpCas9	negative selection	2275766
4123854	4123877	19	-	24336569	HL60	viability	GATGCTGGCCCGGAGGAAGCCGG	MAP2K2	ENSG00000126934	1.301998861816509	[178]	[933]	8	hSpCas9	negative selection	2275767
4117418	4117441	19	-	24336569	KBM7	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	0.4509755398915716	[323]	[1207]	4	hSpCas9	negative selection	2342935
4117480	4117503	19	-	24336569	KBM7	viability	AGGATCTCAGAGCTGGGCGCGGG	MAP2K2	ENSG00000126934	0.8607968338352184	[491]	[2436]	7	hSpCas9	negative selection	2342936
4117486	4117509	19	-	24336569	KBM7	viability	TTCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	0.8279424253379268	[972]	[4710]	7	hSpCas9	negative selection	2342937
4117559	4117582	19	-	24336569	KBM7	viability	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	1.280483767526053	[381]	[2530]	9	hSpCas9	negative selection	2342938
4117616	4117639	19	-	24336569	KBM7	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.26641517740681575	[765]	[2512]	2	hSpCas9	negative selection	2342939
4123780	4123803	19	+	24336569	KBM7	viability	TCACTCGGAGGCGCCCTCGCTGG	MAP2K2	ENSG00000126934	0.023868419828508847	[999]	[2772]	0	hSpCas9	negative selection	2342940
4123785	4123808	19	+	24336569	KBM7	viability	CGGAGGCGCCCTCGCTGGTAGGG	MAP2K2	ENSG00000126934	0.5867327745880451	[321]	[1318]	5	hSpCas9	negative selection	2342941
4123835	4123858	19	+	24336569	KBM7	viability	ATGGTGAGCGCCGGCAGCACCGG	MAP2K2	ENSG00000126934	0.36119152055943016	[581]	[2038]	3	hSpCas9	negative selection	2342942
4123845	4123868	19	-	24336569	KBM7	viability	CCGGAGGAAGCCGGTGCTGCCGG	MAP2K2	ENSG00000126934	1.347497395730285	[589]	[4094]	9	hSpCas9	negative selection	2342943
4123854	4123877	19	-	24336569	KBM7	viability	GATGCTGGCCCGGAGGAAGCCGG	MAP2K2	ENSG00000126934	0.36955674630130697	[209]	[739]	3	hSpCas9	negative selection	2342944
4101114	4101137	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGTTCACGAGGATGTTGGAGGG	MAP2K2	ENSG00000126934	0.004875610045952217	[5,4]	[5,3]	0	hSpCas9	positive selection	3001106
4101270	4101293	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCCCCTGCAGGTTCTCCGGGG	MAP2K2	ENSG00000126934	0.1703792847638215	[3,2]	[1,4]	3	hSpCas9	positive selection	3001107
4110553	4110576	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACATCGTGGGCTTCTACGGGG	MAP2K2	ENSG00000126934	-0.0805044919943356	[3,3]	[1,3]	-1	hSpCas9	positive selection	3001108
4123827	4123850	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGGGTTGATGGTGAGCGCCGG	MAP2K2	ENSG00000126934	0.43491190892508996	[5,5]	[4,7]	8	hSpCas9	positive selection	3001109
4101114	4101137	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGTTCACGAGGATGTTGGAGGG	MAP2K2	ENSG00000126934	0.44470590914971914	[5,5]	[5,4]	7	hSpCas9	positive selection	3068964
4101270	4101293	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCCCCTGCAGGTTCTCCGGGG	MAP2K2	ENSG00000126934	-0.05706768590150466	[3,3]	[3,1]	-1	hSpCas9	positive selection	3068965
4110553	4110576	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACATCGTGGGCTTCTACGGGG	MAP2K2	ENSG00000126934	-0.023140630931458503	[3,3]	[4,0]	0	hSpCas9	positive selection	3068966
4123827	4123850	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGGGTTGATGGTGAGCGCCGG	MAP2K2	ENSG00000126934	-0.12594714614960678	[5,5]	[4,2]	-2	hSpCas9	positive selection	3068967
4110565	4110588		-	24336571	A375	resistance to PLX after 7 days	ATGCAACTCGCCGTACATCGTGG	MAP2K2	ENSG00000126934	-0.17697362303118955	[13,12]	[9,12]	-5	hSpCas9	positive selection	3126246
4110598	4110621		-	24336571	A375	resistance to PLX after 7 days	CCAGATCATCCGCGAGCTGCAGG	MAP2K2	ENSG00000126934	-0.07857120473392695	[10,11]	[9,11]	-2	hSpCas9	positive selection	3126247
4117619	4117642		-	24336571	A375	resistance to PLX after 7 days	GGGTCTCTGCAGGGCAAACCTGG	MAP2K2	ENSG00000126934	0.03635462087761121	[7,7]	[7,7]	1	hSpCas9	positive selection	3126248
4117563	4117586		-	24336571	A375	resistance to PLX after 7 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.3713139076558294	[3,2]	[1,2]	-9	hSpCas9	positive selection	3126249
4110565	4110588		-	24336571	A375	resistance to PLX after 14 days	ATGCAACTCGCCGTACATCGTGG	MAP2K2	ENSG00000126934	0.6142142615262205	[11,12]	[6,9]	5	hSpCas9	positive selection	3184039
4110598	4110621		-	24336571	A375	resistance to PLX after 14 days	CCAGATCATCCGCGAGCTGCAGG	MAP2K2	ENSG00000126934	-0.8878669224127018	[9,14]	[1,2]	-9	hSpCas9	positive selection	3184040
4117619	4117642		-	24336571	A375	resistance to PLX after 14 days	GGGTCTCTGCAGGGCAAACCTGG	MAP2K2	ENSG00000126934	1.3991575464373232	[12,6]	[13,10]	8	hSpCas9	positive selection	3184041
4117563	4117586		-	24336571	A375	resistance to PLX after 14 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.5298548269405785	[2,1]	[1,1]	5	hSpCas9	positive selection	3184042
4110565	4110588		-	24336571	A375	viability after 7 days	ATGCAACTCGCCGTACATCGTGG	MAP2K2	ENSG00000126934	0.5345713992580174	[9]	[13,12]	7	hSpCas9	negative selection	3241832
4110598	4110621		-	24336571	A375	viability after 7 days	CCAGATCATCCGCGAGCTGCAGG	MAP2K2	ENSG00000126934	-0.16719077482047467	[13]	[10,11]	-2	hSpCas9	negative selection	3241833
4117619	4117642		-	24336571	A375	viability after 7 days	GGGTCTCTGCAGGGCAAACCTGG	MAP2K2	ENSG00000126934	0.2702533444044225	[6]	[7,7]	4	hSpCas9	negative selection	3241834
4117563	4117586		-	24336571	A375	viability after 7 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.22681667128730854	[4]	[3,2]	-3	hSpCas9	negative selection	3241835
4110565	4110588		-	24336571	A375	viability after 14 days	ATGCAACTCGCCGTACATCGTGG	MAP2K2	ENSG00000126934	0.4601889726620333	[9]	[11,12]	6	hSpCas9	negative selection	3299625
4110598	4110621		-	24336571	A375	viability after 14 days	CCAGATCATCCGCGAGCTGCAGG	MAP2K2	ENSG00000126934	-0.01844960404334794	[13]	[9,14]	0	hSpCas9	negative selection	3299626
4117619	4117642		-	24336571	A375	viability after 14 days	GGGTCTCTGCAGGGCAAACCTGG	MAP2K2	ENSG00000126934	0.5760608297059224	[6]	[12,6]	7	hSpCas9	negative selection	3299627
4117563	4117586		-	24336571	A375	viability after 14 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.6443001381940878	[4]	[2,1]	-7	hSpCas9	negative selection	3299628
4102438	4102461	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	3.935398116558473	[9,9]	[0,0]	9	hSpCas9	positive selection	3378373
4102375	4102398	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.3504356158373165	[119,119]	[0,0]	1	hSpCas9	positive selection	3378374
4117563	4117586	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.3384629741712407	[120,120]	[0,0]	1	hSpCas9	positive selection	3378375
4101113	4101136	19	+	26780180	HT29	viability (Avana library 4 designs)	GAGTTCACGAGGATGTTGGAGGG	MAP2K2	ENSG00000126934	0.643905778257424	[]	[]	2	hSpCas9	negative selection	3438748
4101270	4101293	19	-	26780180	HT29	viability (Avana library 4 designs)	GCTCCCCTGCAGGTTCTCCGGGG	MAP2K2	ENSG00000126934	0.976494153405118	[]	[]	4	hSpCas9	negative selection	3438749
4110553	4110576	19	-	26780180	HT29	viability (Avana library 4 designs)	GTACATCGTGGGCTTCTACGGGG	MAP2K2	ENSG00000126934	0.119466171669617	[]	[]	0	hSpCas9	negative selection	3438750
4123826	4123849	19	+	26780180	HT29	viability (Avana library 4 designs)	GTAGGGTTGATGGTGAGCGCCGG	MAP2K2	ENSG00000126934	2.02393626827936	[]	[]	7	hSpCas9	negative selection	3438751
4110553	4110576	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACATCGTGGGCTTCTACGGGG	MAP2K2	ENSG00000126934	3.06240862998568	[]	[]	5	hSpCas9	negative selection	3528153
4123826	4123849	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGGGTTGATGGTGAGCGCCGG	MAP2K2	ENSG00000126934	-1.09451629631297	[]	[]	-1	hSpCas9	negative selection	3528154
4101270	4101293	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCCCCTGCAGGTTCTCCGGGG	MAP2K2	ENSG00000126934	4.66688790674779	[]	[]	7	hSpCas9	negative selection	3528155
4101113	4101136	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTTCACGAGGATGTTGGAGGG	MAP2K2	ENSG00000126934	-0.0014847152316031	[]	[]	0	hSpCas9	negative selection	3528156
4102402	4102425	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGGCCAAGAGGATTCCCGAGG	MAP2K2	ENSG00000126934	1.54605207752624	[]	[]	2	hSpCas9	negative selection	3528157
4117469	4117492	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGGCGCGGGCAACGGCGGGG	MAP2K2	ENSG00000126934	1.03154557485159	[]	[]	1	hSpCas9	negative selection	3528158
4110553	4110576	19	-	26780180	A375	viability (Avana lentiGuide)	GTACATCGTGGGCTTCTACGGGG	MAP2K2	ENSG00000126934	0.104312637142488	[]	[]	0	hSpCas9	negative selection	3636812
4123826	4123849	19	+	26780180	A375	viability (Avana lentiGuide)	GTAGGGTTGATGGTGAGCGCCGG	MAP2K2	ENSG00000126934	12.3418229035008	[]	[]	7	hSpCas9	negative selection	3636813
4101270	4101293	19	-	26780180	A375	viability (Avana lentiGuide)	GCTCCCCTGCAGGTTCTCCGGGG	MAP2K2	ENSG00000126934	-0.848582838188849	[]	[]	-1	hSpCas9	negative selection	3636814
4101113	4101136	19	+	26780180	A375	viability (Avana lentiGuide)	GAGTTCACGAGGATGTTGGAGGG	MAP2K2	ENSG00000126934	5.60222060465273	[]	[]	5	hSpCas9	negative selection	3636815
4102402	4102425	19	-	26780180	A375	viability (Avana lentiGuide)	AGAGGCCAAGAGGATTCCCGAGG	MAP2K2	ENSG00000126934	3.4881119403295	[]	[]	3	hSpCas9	negative selection	3636816
4117469	4117492	19	-	26780180	A375	viability (Avana lentiGuide)	GCTGGGCGCGGGCAACGGCGGGG	MAP2K2	ENSG00000126934	17.5439944354838	[]	[]	8	hSpCas9	negative selection	3636817
4110553	4110576	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACATCGTGGGCTTCTACGGGG	MAP2K2	ENSG00000126934	-0.035608070231351686	[4]	[4,4]	0	hSpCas9	positive selection	3745471
4123826	4123849	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGGGTTGATGGTGAGCGCCGG	MAP2K2	ENSG00000126934	-0.3001166696196915	[5]	[5,3]	-4	hSpCas9	positive selection	3745472
4101270	4101293	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCCCCTGCAGGTTCTCCGGGG	MAP2K2	ENSG00000126934	-0.20162183391680316	[4]	[4,2]	-3	hSpCas9	positive selection	3745473
4101113	4101136	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTTCACGAGGATGTTGGAGGG	MAP2K2	ENSG00000126934	-0.01037695011510159	[6]	[6,6]	0	hSpCas9	positive selection	3745474
4102402	4102425	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGGCCAAGAGGATTCCCGAGG	MAP2K2	ENSG00000126934	0.21691967848282528	[5]	[6,6]	6	hSpCas9	positive selection	3745475
4117469	4117492	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGGCGCGGGCAACGGCGGGG	MAP2K2	ENSG00000126934	-0.11268397158379662	[3]	[3,2]	-2	hSpCas9	positive selection	3745476
4110553	4110576	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACATCGTGGGCTTCTACGGGG	MAP2K2	ENSG00000126934	0.11851446324323427	[5]	[4,5]	2	hSpCas9	positive selection	3854078
4123826	4123849	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGGGTTGATGGTGAGCGCCGG	MAP2K2	ENSG00000126934	-0.24923462091037557	[7]	[6,3]	-3	hSpCas9	positive selection	3854079
4101270	4101293	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCCCCTGCAGGTTCTCCGGGG	MAP2K2	ENSG00000126934	0.3023406897035448	[5]	[5,5]	8	hSpCas9	positive selection	3854080
4101113	4101136	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTTCACGAGGATGTTGGAGGG	MAP2K2	ENSG00000126934	0.06397503186894887	[7]	[5,7]	1	hSpCas9	positive selection	3854081
4102402	4102425	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGGCCAAGAGGATTCCCGAGG	MAP2K2	ENSG00000126934	-0.027004375697182947	[6]	[6,4]	0	hSpCas9	positive selection	3854082
4117469	4117492	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGGCGCGGGCAACGGCGGGG	MAP2K2	ENSG00000126934	-0.9259705419142436	[3]	[1,0]	-8	hSpCas9	positive selection	3854083
4102438	4102461	19	-	26780180	A375	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.142385720370303	[]	[]	0	hSpCas9	negative selection	3959592
4102375	4102398	19	-	26780180	A375	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.582942003138361	[]	[]	1	hSpCas9	negative selection	3959593
4110530	4110553	19	+	26780180	A375	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.793931443785486	[]	[]	3	hSpCas9	negative selection	3959594
4110537	4110560	19	-	26780180	A375	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.16061205234758	[]	[]	0	hSpCas9	negative selection	3959595
4117616	4117639	19	-	26780180	A375	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.394874238738551	[]	[]	0	hSpCas9	negative selection	3959596
4117563	4117586	19	-	26780180	A375	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	1.49785859290482	[]	[]	8	hSpCas9	negative selection	3959597
4102438	4102461	19	-	26780180	HT29	viability (GeCKOv2 library)	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.450131468608971	[]	[]	1	hSpCas9	negative selection	4067558
4102375	4102398	19	-	26780180	HT29	viability (GeCKOv2 library)	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	1.27431234466918	[]	[]	6	hSpCas9	negative selection	4067559
4110530	4110553	19	+	26780180	HT29	viability (GeCKOv2 library)	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.616070518354083	[]	[]	2	hSpCas9	negative selection	4067560
4110537	4110560	19	-	26780180	HT29	viability (GeCKOv2 library)	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.199247925385633	[]	[]	0	hSpCas9	negative selection	4067561
4117616	4117639	19	-	26780180	HT29	viability (GeCKOv2 library)	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.489401350785784	[]	[]	1	hSpCas9	negative selection	4067562
4117563	4117586	19	-	26780180	HT29	viability (GeCKOv2 library)	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.506083222091698	[]	[]	1	hSpCas9	negative selection	4067563
4110565	4110588	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGCAACTCGCCGTACATCGTGG	MAP2K2	ENSG00000126934	0.29504774210429224	[3]	[3,3]	7	hSpCas9	positive selection	4150462
4110598	4110621	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGATCATCCGCGAGCTGCAGG	MAP2K2	ENSG00000126934	-0.28766804104864757	[3]	[1,1]	-6	hSpCas9	positive selection	4150463
4117619	4117642	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGTCTCTGCAGGGCAAACCTGG	MAP2K2	ENSG00000126934	0.4194041183927564	[2]	[1,3]	8	hSpCas9	positive selection	4150464
4117563	4117586	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.46072195774353	[1]	[0,0]	-8	hSpCas9	positive selection	4150465
4110565	4110588	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGCAACTCGCCGTACATCGTGG	MAP2K2	ENSG00000126934	0.3515558012049813	[3]	[2,0,5,0]	2	hSpCas9	positive selection	4214484
4110598	4110621	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGATCATCCGCGAGCTGCAGG	MAP2K2	ENSG00000126934	-0.5387103738203172	[3]	[0,0,1,0]	-7	hSpCas9	positive selection	4214485
4117619	4117642	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGTCTCTGCAGGGCAAACCTGG	MAP2K2	ENSG00000126934	-0.5046231061867339	[3]	[1,0,0,0]	-7	hSpCas9	positive selection	4214486
4117563	4117586	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.8061189345107832	[4]	[0,1,0,0]	-9	hSpCas9	positive selection	4214487
4110537	4110560	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.590826067712714	[0]	[1,0]	9	hSpCas9	positive selection	4281801
4110530	4110553	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.28242108178745984	[2]	[3,1]	5	hSpCas9	positive selection	4281802
4117616	4117639	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.25351090825748623	[0]	[0,0]	-5	hSpCas9	positive selection	4281803
4102438	4102461	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.25033357864724526	[1]	[1,0]	5	hSpCas9	positive selection	4346059
4102375	4102398	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.1434750275377597	[2]	[2,1]	3	hSpCas9	positive selection	4346060
4117563	4117586	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.9445268142335805	[3]	[3,6]	9	hSpCas9	positive selection	4346061
4099277	4099299	19	-	27760321	OCIAML3	viability	GCTGGAGGCCATCTTTGGCCGG	MAP2K2	ENSG00000126934	-0.2612952941734341	[528,448]	[228,433]	-3	hSpCas9	negative selection	4416545
4099399	4099421	19	-	27760321	OCIAML3	viability	CTGCAGCCGGAGCGGTTGCAGG	MAP2K2	ENSG00000126934	0.6124185145833136	[645,535]	[591,848]	7	hSpCas9	negative selection	4416546
4101224	4101246	19	+	27760321	OCIAML3	viability	CTTACCTCGGTGCATGATCTGG	MAP2K2	ENSG00000126934	0.4244577008105923	[377,376]	[347,461]	5	hSpCas9	negative selection	4416547
4110564	4110586	19	-	27760321	OCIAML3	viability	GCAACTCGCCGTACATCGTGGG	MAP2K2	ENSG00000126934	-0.7104754886578669	[626,585]	[276,306]	-6	hSpCas9	negative selection	4416548
4117486	4117508	19	-	27760321	OCIAML3	viability	TCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	0.029064993622554325	[377,296]	[234,309]	0	hSpCas9	negative selection	4416549
4099277	4099299	19	-	27760321	OCIAML2	viability	GCTGGAGGCCATCTTTGGCCGG	MAP2K2	ENSG00000126934	-0.20824989381468853	[528,448]	[285,413]	-3	hSpCas9	negative selection	4500008
4099399	4099421	19	-	27760321	OCIAML2	viability	CTGCAGCCGGAGCGGTTGCAGG	MAP2K2	ENSG00000126934	-1.690271294483221	[645,535]	[115,188]	-8	hSpCas9	negative selection	4500009
4101224	4101246	19	+	27760321	OCIAML2	viability	CTTACCTCGGTGCATGATCTGG	MAP2K2	ENSG00000126934	-2.3448963282836415	[377,376]	[36,90]	-9	hSpCas9	negative selection	4500010
4110564	4110586	19	-	27760321	OCIAML2	viability	GCAACTCGCCGTACATCGTGGG	MAP2K2	ENSG00000126934	-3.5056195782659656	[626,585]	[31,57]	-9	hSpCas9	negative selection	4500011
4117486	4117508	19	-	27760321	OCIAML2	viability	TCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	-0.8694887028249749	[377,296]	[81,235]	-7	hSpCas9	negative selection	4500012
4099277	4099299	19	-	27760321	MV411	viability	GCTGGAGGCCATCTTTGGCCGG	MAP2K2	ENSG00000126934	-0.026856702907416152	[528,448]	[379,218]	0	hSpCas9	negative selection	4583471
4099399	4099421	19	-	27760321	MV411	viability	CTGCAGCCGGAGCGGTTGCAGG	MAP2K2	ENSG00000126934	-1.4601645245073136	[645,535]	[55,268]	-7	hSpCas9	negative selection	4583472
4101224	4101246	19	+	27760321	MV411	viability	CTTACCTCGGTGCATGATCTGG	MAP2K2	ENSG00000126934	0.3174186648277555	[377,376]	[75,664]	2	hSpCas9	negative selection	4583473
4110564	4110586	19	-	27760321	MV411	viability	GCAACTCGCCGTACATCGTGGG	MAP2K2	ENSG00000126934	-0.14336177037235664	[626,585]	[308,442]	-1	hSpCas9	negative selection	4583474
4117486	4117508	19	-	27760321	MV411	viability	TCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	-0.439951983470737	[377,296]	[41,344]	-3	hSpCas9	negative selection	4583475
4099277	4099299	19	-	27760321	HL60	viability	GCTGGAGGCCATCTTTGGCCGG	MAP2K2	ENSG00000126934	-0.009321779062217761	[528,448]	[362,429]	0	hSpCas9	negative selection	4666934
4099399	4099421	19	-	27760321	HL60	viability	CTGCAGCCGGAGCGGTTGCAGG	MAP2K2	ENSG00000126934	-0.08779546127909027	[645,535]	[461,441]	-1	hSpCas9	negative selection	4666935
4101224	4101246	19	+	27760321	HL60	viability	CTTACCTCGGTGCATGATCTGG	MAP2K2	ENSG00000126934	0.2759735799060316	[377,376]	[326,424]	3	hSpCas9	negative selection	4666936
4110564	4110586	19	-	27760321	HL60	viability	GCAACTCGCCGTACATCGTGGG	MAP2K2	ENSG00000126934	-0.2218433482106677	[626,585]	[359,493]	-3	hSpCas9	negative selection	4666937
4117486	4117508	19	-	27760321	HL60	viability	TCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	0.4678108096107909	[377,296]	[321,438]	5	hSpCas9	negative selection	4666938
4099277	4099299	19	-	27760321	HT1080	viability	GCTGGAGGCCATCTTTGGCCGG	MAP2K2	ENSG00000126934	0.2661310137773156	[448,350]	[257,118]	1	hSpCas9	negative selection	4750397
4099399	4099421	19	-	27760321	HT1080	viability	CTGCAGCCGGAGCGGTTGCAGG	MAP2K2	ENSG00000126934	-0.5867064176949713	[535,417]	[126,125]	-3	hSpCas9	negative selection	4750398
4101224	4101246	19	+	27760321	HT1080	viability	CTTACCTCGGTGCATGATCTGG	MAP2K2	ENSG00000126934	-1.1957448019835337	[376,293]	[33,84]	-5	hSpCas9	negative selection	4750399
4110564	4110586	19	-	27760321	HT1080	viability	GCAACTCGCCGTACATCGTGGG	MAP2K2	ENSG00000126934	-2.4082174149633953	[585,456]	[41,35]	-7	hSpCas9	negative selection	4750400
4117486	4117508	19	-	27760321	HT1080	viability	TCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	-1.6581805982358886	[296,231]	[30,35]	-5	hSpCas9	negative selection	4750401
4099277	4099299	19	-	27760321	HT29	viability after 7 days	GCTGGAGGCCATCTTTGGCCGG	MAP2K2	ENSG00000126934	0.2502219186634842	[448,350]	[831,683,357]	4	hSpCas9	negative selection	4833860
4099399	4099421	19	-	27760321	HT29	viability after 7 days	CTGCAGCCGGAGCGGTTGCAGG	MAP2K2	ENSG00000126934	-0.32160557412288204	[535,417]	[414,502,540]	-4	hSpCas9	negative selection	4833861
4101224	4101246	19	+	27760321	HT29	viability after 7 days	CTTACCTCGGTGCATGATCTGG	MAP2K2	ENSG00000126934	-0.4198562787899077	[376,293]	[390,212,370]	-6	hSpCas9	negative selection	4833862
4110564	4110586	19	-	27760321	HT29	viability after 7 days	GCAACTCGCCGTACATCGTGGG	MAP2K2	ENSG00000126934	-0.5154158385030949	[585,456]	[436,466,496]	-6	hSpCas9	negative selection	4833863
4117486	4117508	19	-	27760321	HT29	viability after 7 days	TCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	0.3474318542705838	[296,231]	[338,572,373]	5	hSpCas9	negative selection	4833864
4099277	4099299	19	-	27760321	HT29	viability after 25 days	GCTGGAGGCCATCTTTGGCCGG	MAP2K2	ENSG00000126934	-0.40687169438463017	[448,350]	[556,166,290]	-4	hSpCas9	negative selection	4917323
4099399	4099421	19	-	27760321	HT29	viability after 25 days	CTGCAGCCGGAGCGGTTGCAGG	MAP2K2	ENSG00000126934	0.18566591371999075	[535,417]	[420,851,595]	1	hSpCas9	negative selection	4917324
4101224	4101246	19	+	27760321	HT29	viability after 25 days	CTTACCTCGGTGCATGATCTGG	MAP2K2	ENSG00000126934	-0.029667164092807827	[376,293]	[255,499,377]	0	hSpCas9	negative selection	4917325
4110564	4110586	19	-	27760321	HT29	viability after 25 days	GCAACTCGCCGTACATCGTGGG	MAP2K2	ENSG00000126934	-0.5758639133112333	[585,456]	[361,561,262]	-5	hSpCas9	negative selection	4917326
4117486	4117508	19	-	27760321	HT29	viability after 25 days	TCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	0.04847025985810377	[296,231]	[256,378,303]	0	hSpCas9	negative selection	4917327
4099277	4099299	19	-	27760321	HT29	viability after 22 days	GCTGGAGGCCATCTTTGGCCGG	MAP2K2	ENSG00000126934	-0.05021001745410053	[448,350]	[543,272,520]	0	hSpCas9	negative selection	5000786
4099399	4099421	19	-	27760321	HT29	viability after 22 days	CTGCAGCCGGAGCGGTTGCAGG	MAP2K2	ENSG00000126934	0.26497156948517	[535,417]	[589,493,907]	2	hSpCas9	negative selection	5000787
4101224	4101246	19	+	27760321	HT29	viability after 22 days	CTTACCTCGGTGCATGATCTGG	MAP2K2	ENSG00000126934	-0.9425120305502414	[376,293]	[132,298,174]	-6	hSpCas9	negative selection	5000788
4110564	4110586	19	-	27760321	HT29	viability after 22 days	GCAACTCGCCGTACATCGTGGG	MAP2K2	ENSG00000126934	-0.9965765968108622	[585,456]	[309,314,280]	-6	hSpCas9	negative selection	5000789
4117486	4117508	19	-	27760321	HT29	viability after 22 days	TCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	0.6105815936194001	[296,231]	[581,409,404]	6	hSpCas9	negative selection	5000790
4099277	4099299	19	-	27760321	HT29	viability after 19 days	GCTGGAGGCCATCTTTGGCCGG	MAP2K2	ENSG00000126934	-0.1038716580547243	[448,350]	[588,439,270]	-1	hSpCas9	negative selection	5084249
4099399	4099421	19	-	27760321	HT29	viability after 19 days	CTGCAGCCGGAGCGGTTGCAGG	MAP2K2	ENSG00000126934	0.21230650102123172	[535,417]	[744,439,718]	2	hSpCas9	negative selection	5084250
4101224	4101246	19	+	27760321	HT29	viability after 19 days	CTTACCTCGGTGCATGATCTGG	MAP2K2	ENSG00000126934	0.13481002110287316	[376,293]	[411,521,331]	1	hSpCas9	negative selection	5084251
4110564	4110586	19	-	27760321	HT29	viability after 19 days	GCAACTCGCCGTACATCGTGGG	MAP2K2	ENSG00000126934	-0.24439624754464667	[585,456]	[835,530,189]	-2	hSpCas9	negative selection	5084252
4117486	4117508	19	-	27760321	HT29	viability after 19 days	TCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	0.6729857635399976	[296,231]	[419,453,562]	6	hSpCas9	negative selection	5084253
4099277	4099299	19	-	27760321	HT29	viability after 16 days	GCTGGAGGCCATCTTTGGCCGG	MAP2K2	ENSG00000126934	-0.16816554505813233	[448,350]	[534,352,320]	-2	hSpCas9	negative selection	5167712
4099399	4099421	19	-	27760321	HT29	viability after 16 days	CTGCAGCCGGAGCGGTTGCAGG	MAP2K2	ENSG00000126934	0.005095696929116433	[535,417]	[410,678,500]	0	hSpCas9	negative selection	5167713
4101224	4101246	19	+	27760321	HT29	viability after 16 days	CTTACCTCGGTGCATGATCTGG	MAP2K2	ENSG00000126934	0.2241128633611538	[376,293]	[232,544,514]	2	hSpCas9	negative selection	5167714
4110564	4110586	19	-	27760321	HT29	viability after 16 days	GCAACTCGCCGTACATCGTGGG	MAP2K2	ENSG00000126934	-1.3002421492398524	[585,456]	[308,293,112]	-7	hSpCas9	negative selection	5167715
4117486	4117508	19	-	27760321	HT29	viability after 16 days	TCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	-0.1753020879718339	[296,231]	[362,289,141]	-2	hSpCas9	negative selection	5167716
4099277	4099299	19	-	27760321	HT29	viability after 13 days	GCTGGAGGCCATCTTTGGCCGG	MAP2K2	ENSG00000126934	0.3044255961244389	[448,350]	[696,568,459]	4	hSpCas9	negative selection	5251175
4099399	4099421	19	-	27760321	HT29	viability after 13 days	CTGCAGCCGGAGCGGTTGCAGG	MAP2K2	ENSG00000126934	0.28070620058368045	[535,417]	[717,551,741]	3	hSpCas9	negative selection	5251176
4101224	4101246	19	+	27760321	HT29	viability after 13 days	CTTACCTCGGTGCATGATCTGG	MAP2K2	ENSG00000126934	-0.4697272549065983	[376,293]	[182,271,381]	-5	hSpCas9	negative selection	5251177
4110564	4110586	19	-	27760321	HT29	viability after 13 days	GCAACTCGCCGTACATCGTGGG	MAP2K2	ENSG00000126934	-0.5252338147694537	[585,456]	[458,314,482]	-5	hSpCas9	negative selection	5251178
4117486	4117508	19	-	27760321	HT29	viability after 13 days	TCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	0.2656998823955412	[296,231]	[446,264,392]	3	hSpCas9	negative selection	5251179
4099277	4099299	19	-	27760321	HT29	viability after 10 days	GCTGGAGGCCATCTTTGGCCGG	MAP2K2	ENSG00000126934	0.03789180731184286	[448,350]	[535,417,579]	0	hSpCas9	negative selection	5334638
4099399	4099421	19	-	27760321	HT29	viability after 10 days	CTGCAGCCGGAGCGGTTGCAGG	MAP2K2	ENSG00000126934	-0.11879393683046668	[535,417]	[312,627,702]	-1	hSpCas9	negative selection	5334639
4101224	4101246	19	+	27760321	HT29	viability after 10 days	CTTACCTCGGTGCATGATCTGG	MAP2K2	ENSG00000126934	0.3222216476211341	[376,293]	[918,366,285]	4	hSpCas9	negative selection	5334640
4110564	4110586	19	-	27760321	HT29	viability after 10 days	GCAACTCGCCGTACATCGTGGG	MAP2K2	ENSG00000126934	-0.4971032426847846	[585,456]	[525,454,403]	-6	hSpCas9	negative selection	5334641
4117486	4117508	19	-	27760321	HT29	viability after 10 days	TCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	0.38757927614090626	[296,231]	[345,368,575]	5	hSpCas9	negative selection	5334642
4099277	4099299	19	-	27760321	MOLM13	viability	GCTGGAGGCCATCTTTGGCCGG	MAP2K2	ENSG00000126934	1.09919039326925	[528,448]	[433,720]	7	hSpCas9	negative selection	5418101
4099399	4099421	19	-	27760321	MOLM13	viability	CTGCAGCCGGAGCGGTTGCAGG	MAP2K2	ENSG00000126934	-0.526648142001185	[645,535]	[183,269]	-3	hSpCas9	negative selection	5418102
4101224	4101246	19	+	27760321	MOLM13	viability	CTTACCTCGGTGCATGATCTGG	MAP2K2	ENSG00000126934	0.18730941055851724	[377,376]	[373,131]	1	hSpCas9	negative selection	5418103
4110564	4110586	19	-	27760321	MOLM13	viability	GCAACTCGCCGTACATCGTGGG	MAP2K2	ENSG00000126934	-1.7826803781123577	[626,585]	[85,110]	-7	hSpCas9	negative selection	5418104
4117486	4117508	19	-	27760321	MOLM13	viability	TCGAAAGGATCTCAGAGCTGGG	MAP2K2	ENSG00000126934	0.4652011999166216	[377,296]	[312,216]	3	hSpCas9	negative selection	5418105
4123640	4123663	19	-	27661255	K562	viability	GACGGGGTGAGTGGTGCACGGGG	MAP2K2	ENSG00000126934	0.21734605141007696	[1010,813]	[874,829]	7	dCas9-KRAB	negative selection	5492051
4123674	4123697	19	-	27661255	K562	viability	GAGGAGTGCACGAGGCAGGGGGG	MAP2K2	ENSG00000126934	-0.18682416316823808	[1227,1092]	[888,753]	-5	dCas9-KRAB	negative selection	5492052
4123682	4123705	19	-	27661255	K562	viability	GGGTTCGCGAGGAGTGCACGAGG	MAP2K2	ENSG00000126934	0.09087781542423068	[1136,1215]	[1091,920]	3	dCas9-KRAB	negative selection	5492053
4123716	4123739	19	-	27661255	K562	viability	GGAGCCCTCGGGGAAGGACGGGG	MAP2K2	ENSG00000126934	0.09574561491073653	[603,830]	[730,504]	3	dCas9-KRAB	negative selection	5492054
4123918	4123941	19	-	27661255	K562	viability	GCTCCCGGCCCGCCCCCTATGGG	MAP2K2	ENSG00000126934	-0.024325301093391483	[462,640]	[443,419]	-1	dCas9-KRAB	negative selection	5492055
4124087	4124110	19	-	27661255	K562	viability	GCTGCGGCGTCAGCCTTCTTCGG	MAP2K2	ENSG00000126934	0.4445686720911523	[350,491]	[489,425]	9	dCas9-KRAB	negative selection	5492056
4110537	4110560	19	-	27260156	BXPC3	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.6353843414286695	[10]	[15,43,3,3]	9	hSpCas9	negative selection	5554261
4110530	4110553	19	+	27260156	BXPC3	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.41075536483551317	[372]	[453,441,632,559]	8	hSpCas9	negative selection	5554262
4117616	4117639	19	-	27260156	BXPC3	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.15104940699828218	[42]	[37,37,38,47]	-3	hSpCas9	negative selection	5554263
4102438	4102461	19	-	27260156	BXPC3	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.31792366106272363	[67]	[50,108,84,114]	7	hSpCas9	negative selection	5618519
4102375	4102398	19	-	27260156	BXPC3	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.006871567147836211	[301]	[306,358,287,309]	0	hSpCas9	negative selection	5618520
4117563	4117586	19	-	27260156	BXPC3	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.09581547857617012	[650]	[604,595,600,761]	-2	hSpCas9	negative selection	5618521
4110537	4110560	19	-	27260156	A673	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.47725020598536094	[10]	[22,38,3,6]	9	hSpCas9	negative selection	5675512
4110530	4110553	19	+	27260156	A673	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.277526376734476	[372]	[637,508,444,593]	6	hSpCas9	negative selection	5675513
4117616	4117639	19	-	27260156	A673	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.45929879822106434	[42]	[31,31,55,28]	-8	hSpCas9	negative selection	5675514
4102438	4102461	19	-	27260156	A673	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.5746387337318928	[67]	[126,84,174,98]	9	hSpCas9	negative selection	5739770
4102375	4102398	19	-	27260156	A673	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.09987847025615426	[301]	[347,383,314,303]	-2	hSpCas9	negative selection	5739771
4117563	4117586	19	-	27260156	A673	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.11863404333549032	[650]	[1013,800,767,829]	3	hSpCas9	negative selection	5739772
4110537	4110560	19	-	27260156	A375	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-1.3467181507784218	[10]	[11,6,0,0]	-9	hSpCas9	negative selection	5796763
4110530	4110553	19	+	27260156	A375	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.4013499866582669	[372]	[521,679,623,496]	6	hSpCas9	negative selection	5796764
4117616	4117639	19	-	27260156	A375	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.07077636561937517	[42]	[92,47,16,34]	-1	hSpCas9	negative selection	5796765
4102438	4102461	19	-	27260156	A375	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.2028282103613699	[67]	[57,127,72,108]	3	hSpCas9	negative selection	5861021
4102375	4102398	19	-	27260156	A375	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.3115520415211013	[301]	[364,314,308,165]	-4	hSpCas9	negative selection	5861022
4117563	4117586	19	-	27260156	A375	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.23709132283324608	[650]	[984,857,1201,570]	3	hSpCas9	negative selection	5861023
4110537	4110560	19	-	27260156	COLO741	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.5168112929231352	[10]	[22,37,0]	8	hSpCas9	negative selection	5918014
4110530	4110553	19	+	27260156	COLO741	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.45150766088864147	[372]	[714,676,572]	8	hSpCas9	negative selection	5918015
4117616	4117639	19	-	27260156	COLO741	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.4892174166563743	[42]	[22,25,64]	-8	hSpCas9	negative selection	5918016
4102438	4102461	19	-	27260156	COLO741	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.17333037956991104	[67]	[92,139,62]	3	hSpCas9	negative selection	5982272
4102375	4102398	19	-	27260156	COLO741	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.10867158451850467	[301]	[416,395,432]	2	hSpCas9	negative selection	5982273
4117563	4117586	19	-	27260156	COLO741	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.018734812796447564	[650]	[916,838,780]	0	hSpCas9	negative selection	5982274
4110537	4110560	19	-	27260156	CAL120	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.09381366914190359	[10]	[0,38,1]	1	hSpCas9	negative selection	6039265
4110530	4110553	19	+	27260156	CAL120	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	1.0027700353411353	[372]	[1230,775,829]	9	hSpCas9	negative selection	6039266
4117616	4117639	19	-	27260156	CAL120	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.878595259168057	[42]	[15,21,46]	-8	hSpCas9	negative selection	6039267
4102438	4102461	19	-	27260156	CAL120	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.8209850530266156	[67]	[255,90,117]	9	hSpCas9	negative selection	6103523
4102375	4102398	19	-	27260156	CAL120	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.20298643166621066	[301]	[331,381,565]	3	hSpCas9	negative selection	6103524
4117563	4117586	19	-	27260156	CAL120	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.11475350406327656	[650]	[1065,478,746]	-2	hSpCas9	negative selection	6103525
4110537	4110560	19	-	27260156	CADOES1	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-1.7664019598996958	[10]	[0,4,3,1]	-9	hSpCas9	negative selection	6160516
4110530	4110553	19	+	27260156	CADOES1	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.8593367598554598	[372]	[697,515,725,574]	9	hSpCas9	negative selection	6160517
4117616	4117639	19	-	27260156	CADOES1	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.5296824602142678	[42]	[29,40,7,31]	-7	hSpCas9	negative selection	6160518
4102438	4102461	19	-	27260156	CADOES1	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.7554712002871145	[67]	[113,55,173,81]	9	hSpCas9	negative selection	6224774
4102375	4102398	19	-	27260156	CADOES1	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.22564820128121482	[301]	[394,292,283,341]	4	hSpCas9	negative selection	6224775
4117563	4117586	19	-	27260156	CADOES1	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.14629463603758008	[650]	[673,698,621,685]	2	hSpCas9	negative selection	6224776
4110537	4110560	19	-	27260156	EWS502	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.9192518283759865	[10]	[30,7,3,45]	9	hSpCas9	negative selection	6281767
4110530	4110553	19	+	27260156	EWS502	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.48393056729033435	[372]	[529,497,537,653]	8	hSpCas9	negative selection	6281768
4117616	4117639	19	-	27260156	EWS502	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.3838987326283685	[42]	[82,103,29,11]	6	hSpCas9	negative selection	6281769
4102438	4102461	19	-	27260156	EWS502	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.6745447239573985	[67]	[78,129,114,140]	9	hSpCas9	negative selection	6346025
4102375	4102398	19	-	27260156	EWS502	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.11288159836341183	[301]	[278,384,479,238]	2	hSpCas9	negative selection	6346026
4117563	4117586	19	-	27260156	EWS502	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.004473335412416235	[650]	[705,740,527,789]	0	hSpCas9	negative selection	6346027
4110537	4110560	19	-	27260156	EW8	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-1.5830762689816993	[10]	[9,0,0,0]	-9	hSpCas9	negative selection	6403018
4110530	4110553	19	+	27260156	EW8	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.3915665766123129	[372]	[452,291,357,493]	7	hSpCas9	negative selection	6403019
4117616	4117639	19	-	27260156	EW8	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.04929418900359961	[42]	[31,33,3,78]	0	hSpCas9	negative selection	6403020
4102438	4102461	19	-	27260156	EW8	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.8636240366005441	[67]	[86,75,52,190]	9	hSpCas9	negative selection	6467276
4102375	4102398	19	-	27260156	EW8	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.03886522825427319	[301]	[309,251,266,179]	0	hSpCas9	negative selection	6467277
4117563	4117586	19	-	27260156	EW8	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.1918974467852601	[650]	[472,542,311,544]	-4	hSpCas9	negative selection	6467278
4110537	4110560	19	-	27260156	CORL105	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.28209854807289325	[10]	[33,1,5,19]	5	hSpCas9	negative selection	6524269
4110530	4110553	19	+	27260156	CORL105	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.3565211159643119	[372]	[555,453,673,571]	6	hSpCas9	negative selection	6524270
4117616	4117639	19	-	27260156	CORL105	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.3365171332344854	[42]	[128,56,26,37]	6	hSpCas9	negative selection	6524271
4102438	4102461	19	-	27260156	CORL105	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.287110914729543	[67]	[59,92,89,142]	5	hSpCas9	negative selection	6588527
4102375	4102398	19	-	27260156	CORL105	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.23585331625905864	[301]	[302,466,540,368]	4	hSpCas9	negative selection	6588528
4117563	4117586	19	-	27260156	CORL105	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.4404699144313587	[650]	[521,388,571,765]	-7	hSpCas9	negative selection	6588529
4110537	4110560	19	-	27260156	HS294T	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-0.12493574124236151	[10]	[5,0,1,6]	-2	hSpCas9	negative selection	6645520
4110530	4110553	19	+	27260156	HS294T	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.6569345220827809	[372]	[154,168,190,437]	8	hSpCas9	negative selection	6645521
4117616	4117639	19	-	27260156	HS294T	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.029144084308993623	[42]	[12,12,16,26]	0	hSpCas9	negative selection	6645522
4102438	4102461	19	-	27260156	HS294T	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.43872882610086217	[67]	[14,54,26,48]	6	hSpCas9	negative selection	6709778
4102375	4102398	19	-	27260156	HS294T	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.6169535413365607	[301]	[35,71,110,91]	-7	hSpCas9	negative selection	6709779
4117563	4117586	19	-	27260156	HS294T	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-1.5744237075580703	[650]	[76,72,88,102]	-9	hSpCas9	negative selection	6709780
4110537	4110560	19	-	27260156	HCC44	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.24719765540012872	[10]	[1,20,0,29]	4	hSpCas9	negative selection	6766771
4110530	4110553	19	+	27260156	HCC44	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.6444254227096285	[372]	[996,581,471,592]	9	hSpCas9	negative selection	6766772
4117616	4117639	19	-	27260156	HCC44	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-1.0394400344352506	[42]	[31,22,20,18]	-8	hSpCas9	negative selection	6766773
4102438	4102461	19	-	27260156	HCC44	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	1.0440935352532947	[67]	[337,60,102,151]	9	hSpCas9	negative selection	6831029
4102375	4102398	19	-	27260156	HCC44	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.023966575757440878	[301]	[321,340,497,252]	0	hSpCas9	negative selection	6831030
4117563	4117586	19	-	27260156	HCC44	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.15282937265418906	[650]	[662,973,996,633]	2	hSpCas9	negative selection	6831031
4110537	4110560	19	-	27260156	G402	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-3.7450915210474296	[10]	[0,0,0,0]	-9	hSpCas9	negative selection	6888022
4110530	4110553	19	+	27260156	G402	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.8574375797754639	[372]	[583,458,1068,1112]	9	hSpCas9	negative selection	6888023
4117616	4117639	19	-	27260156	G402	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.41700079359235787	[42]	[72,193,1,20]	5	hSpCas9	negative selection	6888024
4102438	4102461	19	-	27260156	G402	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.08365379227416758	[67]	[122,185,25,29]	1	hSpCas9	negative selection	6952280
4102375	4102398	19	-	27260156	G402	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.14897692858277356	[301]	[574,445,148,205]	-2	hSpCas9	negative selection	6952281
4117563	4117586	19	-	27260156	G402	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.16109659581355917	[650]	[1216,529,813,1008]	2	hSpCas9	negative selection	6952282
4110537	4110560	19	-	27260156	L33	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-0.20145282454344837	[10]	[0,8,5,5]	-4	hSpCas9	negative selection	7009273
4110530	4110553	19	+	27260156	L33	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.5960882297254257	[372]	[441,223,441,566]	9	hSpCas9	negative selection	7009274
4117616	4117639	19	-	27260156	L33	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.7380825175427854	[42]	[38,27,50,98]	9	hSpCas9	negative selection	7009275
4102438	4102461	19	-	27260156	L33	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.27326431290517617	[67]	[95,30,30,106]	6	hSpCas9	negative selection	7073531
4102375	4102398	19	-	27260156	L33	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.3826518011516994	[301]	[411,139,245,428]	7	hSpCas9	negative selection	7073532
4117563	4117586	19	-	27260156	L33	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.7819275201302087	[650]	[315,124,258,481]	-9	hSpCas9	negative selection	7073533
4110537	4110560	19	-	27260156	K562	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-2.1797562064115272	[10]	[5,0,0,0]	-9	hSpCas9	negative selection	7130524
4110530	4110553	19	+	27260156	K562	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.3700977850902668	[372]	[574,504,259,389]	5	hSpCas9	negative selection	7130525
4117616	4117639	19	-	27260156	K562	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-1.563141723519418	[42]	[5,26,7,10]	-9	hSpCas9	negative selection	7130526
4102438	4102461	19	-	27260156	K562	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.34612886162802114	[67]	[19,50,147,80]	4	hSpCas9	negative selection	7194782
4102375	4102398	19	-	27260156	K562	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.5119494007660018	[301]	[233,172,149,195]	-6	hSpCas9	negative selection	7194783
4117563	4117586	19	-	27260156	K562	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.5162624575605723	[650]	[740,717,1296,563]	6	hSpCas9	negative selection	7194784
4110537	4110560	19	-	27260156	HT29	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-0.46702688341734344	[10]	[6,29,0,2]	-7	hSpCas9	negative selection	7251775
4110530	4110553	19	+	27260156	HT29	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.39182252955715785	[372]	[706,568,665,456]	7	hSpCas9	negative selection	7251776
4117616	4117639	19	-	27260156	HT29	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.3783591707914842	[42]	[38,29,71,20]	-6	hSpCas9	negative selection	7251777
4102438	4102461	19	-	27260156	HT29	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.6982128947108248	[67]	[127,169,131,110]	9	hSpCas9	negative selection	7316033
4102375	4102398	19	-	27260156	HT29	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.37617892914359236	[301]	[501,531,486,397]	7	hSpCas9	negative selection	7316034
4117563	4117586	19	-	27260156	HT29	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.09548679855305486	[650]	[836,720,1009,801]	1	hSpCas9	negative selection	7316035
4110537	4110560	19	-	27260156	MHHES1	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-1.3641258862758	[10]	[15,0,2,0]	-9	hSpCas9	negative selection	7373026
4110530	4110553	19	+	27260156	MHHES1	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.3865925062571275	[372]	[483,796,465,471]	7	hSpCas9	negative selection	7373027
4117616	4117639	19	-	27260156	MHHES1	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.3716517960571961	[42]	[91,46,33,74]	6	hSpCas9	negative selection	7373028
4102438	4102461	19	-	27260156	MHHES1	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.293894762096758	[67]	[104,50,122,91]	5	hSpCas9	negative selection	7437284
4102375	4102398	19	-	27260156	MHHES1	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.1308210583847772	[301]	[209,547,352,169]	-2	hSpCas9	negative selection	7437285
4117563	4117586	19	-	27260156	MHHES1	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.1615684802834605	[650]	[863,495,425,794]	-3	hSpCas9	negative selection	7437286
4110537	4110560	19	-	27260156	MEWO	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-0.36541443160419806	[10]	[7,0,14]	-7	hSpCas9	negative selection	7494277
4110530	4110553	19	+	27260156	MEWO	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.3189424582640647	[372]	[368,428,494]	6	hSpCas9	negative selection	7494278
4117616	4117639	19	-	27260156	MEWO	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.11492876686509446	[42]	[29,47,31]	-3	hSpCas9	negative selection	7494279
4102438	4102461	19	-	27260156	MEWO	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.10585445452587106	[67]	[137,35,44]	2	hSpCas9	negative selection	7558535
4102375	4102398	19	-	27260156	MEWO	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.38309485396683	[301]	[336,415,345]	7	hSpCas9	negative selection	7558536
4117563	4117586	19	-	27260156	MEWO	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.2266095426824774	[650]	[712,465,419]	-5	hSpCas9	negative selection	7558537
4110537	4110560	19	-	27260156	LNCAPCLONEFGC	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-0.2687390320956631	[10]	[3,13,2,10]	-4	hSpCas9	negative selection	7615528
4110530	4110553	19	+	27260156	LNCAPCLONEFGC	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.5941009405883706	[372]	[559,483,559,443]	8	hSpCas9	negative selection	7615529
4117616	4117639	19	-	27260156	LNCAPCLONEFGC	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.7892778831554668	[42]	[19,7,34,29]	-8	hSpCas9	negative selection	7615530
4102438	4102461	19	-	27260156	LNCAPCLONEFGC	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.2583776383492422	[67]	[32,86,89,86]	4	hSpCas9	negative selection	7679786
4102375	4102398	19	-	27260156	LNCAPCLONEFGC	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.12833793574876673	[301]	[222,248,333,207]	-2	hSpCas9	negative selection	7679787
4117563	4117586	19	-	27260156	LNCAPCLONEFGC	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.04625114609510572	[650]	[621,607,513,676]	0	hSpCas9	negative selection	7679788
4110537	4110560	19	-	27260156	PANC0327	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-1.1391374872657156	[10]	[1,0,10,3]	-8	hSpCas9	negative selection	7736779
4110530	4110553	19	+	27260156	PANC0327	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.35837959998116453	[372]	[489,588,310,292]	5	hSpCas9	negative selection	7736780
4117616	4117639	19	-	27260156	PANC0327	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	1.612225216770197	[42]	[129,110,154,72]	9	hSpCas9	negative selection	7736781
4102438	4102461	19	-	27260156	PANC0327	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.9743825667490338	[67]	[82,100,109,179]	9	hSpCas9	negative selection	7801037
4102375	4102398	19	-	27260156	PANC0327	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.06473813202391576	[301]	[357,199,289,290]	0	hSpCas9	negative selection	7801038
4117563	4117586	19	-	27260156	PANC0327	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.12406886629192349	[650]	[834,398,508,823]	1	hSpCas9	negative selection	7801039
4110537	4110560	19	-	27260156	NCIH2009	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.3696459908963474	[10]	[65,0,1]	5	hSpCas9	negative selection	7858030
4110530	4110553	19	+	27260156	NCIH2009	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.879428400144393	[372]	[1346,1027,574]	9	hSpCas9	negative selection	7858031
4117616	4117639	19	-	27260156	NCIH2009	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.1509814629602242	[42]	[82,23,96]	2	hSpCas9	negative selection	7858032
4102438	4102461	19	-	27260156	NCIH2009	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.8941394957834914	[67]	[182,158,188]	9	hSpCas9	negative selection	7922288
4102375	4102398	19	-	27260156	NCIH2009	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.1237276866478021	[301]	[415,445,507]	1	hSpCas9	negative selection	7922289
4117563	4117586	19	-	27260156	NCIH2009	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.6274398817446137	[650]	[1152,469,255]	-7	hSpCas9	negative selection	7922290
4110537	4110560	19	-	27260156	NCIH1373	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-1.530989939787852	[10]	[12,0,0,0]	-9	hSpCas9	negative selection	7979281
4110530	4110553	19	+	27260156	NCIH1373	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	1.056855187236015	[372]	[925,601,848,302]	9	hSpCas9	negative selection	7979282
4117616	4117639	19	-	27260156	NCIH1373	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.5219434579938009	[42]	[194,19,39,11]	5	hSpCas9	negative selection	7979283
4102438	4102461	19	-	27260156	NCIH1373	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	1.0482655833712085	[67]	[373,123,50,30]	9	hSpCas9	negative selection	8043539
4102375	4102398	19	-	27260156	NCIH1373	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.3507949922439565	[301]	[288,173,230,101]	-4	hSpCas9	negative selection	8043540
4117563	4117586	19	-	27260156	NCIH1373	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.4464323448993615	[650]	[869,711,171,109]	-4	hSpCas9	negative selection	8043541
4110537	4110560	19	-	27260156	PATU8902	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.08290167652925984	[10]	[23,39,0,1]	0	hSpCas9	negative selection	8100532
4110530	4110553	19	+	27260156	PATU8902	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	1.045540413459136	[372]	[992,917,769,1760]	9	hSpCas9	negative selection	8100533
4117616	4117639	19	-	27260156	PATU8902	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.06307029633545813	[42]	[66,29,2,178]	0	hSpCas9	negative selection	8100534
4102438	4102461	19	-	27260156	PATU8902	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.3501593299500585	[67]	[11,192,91,203]	3	hSpCas9	negative selection	8164790
4102375	4102398	19	-	27260156	PATU8902	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.4353397904675373	[301]	[354,337,845,673]	4	hSpCas9	negative selection	8164791
4117563	4117586	19	-	27260156	PATU8902	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.3352483883535796	[650]	[1035,707,1133,1764]	3	hSpCas9	negative selection	8164792
4110537	4110560	19	-	27260156	PANC1	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	2.4574266887677685	[10]	[51,46,102,10]	9	hSpCas9	negative selection	8221783
4110530	4110553	19	+	27260156	PANC1	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.6420171955078233	[372]	[398,601,449,553]	9	hSpCas9	negative selection	8221784
4117616	4117639	19	-	27260156	PANC1	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.2746700551830563	[42]	[19,60,42,7]	-4	hSpCas9	negative selection	8221785
4102438	4102461	19	-	27260156	PANC1	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.5775789774149169	[67]	[41,137,106,73]	8	hSpCas9	negative selection	8286041
4102375	4102398	19	-	27260156	PANC1	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.04999769249485553	[301]	[160,376,251,298]	0	hSpCas9	negative selection	8286042
4117563	4117586	19	-	27260156	PANC1	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.029009293008774528	[650]	[608,543,623,424]	0	hSpCas9	negative selection	8286043
4110537	4110560	19	-	27260156	PANC0813	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.4145812607232493	[10]	[8,10,27,19]	6	hSpCas9	negative selection	8343034
4110530	4110553	19	+	27260156	PANC0813	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.4754908178188896	[372]	[685,564,466,717]	7	hSpCas9	negative selection	8343035
4117616	4117639	19	-	27260156	PANC0813	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.6664091527658758	[42]	[70,163,33,51]	9	hSpCas9	negative selection	8343036
4102438	4102461	19	-	27260156	PANC0813	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.42666461747931983	[67]	[56,124,156,86]	7	hSpCas9	negative selection	8407292
4102375	4102398	19	-	27260156	PANC0813	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.13158483797692555	[301]	[291,481,277,243]	-2	hSpCas9	negative selection	8407293
4117563	4117586	19	-	27260156	PANC0813	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-1.229497413158351	[650]	[450,404,209,252]	-9	hSpCas9	negative selection	8407294
4110537	4110560	19	-	27260156	RDES	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.31637478168977307	[10]	[2,17,19,25]	5	hSpCas9	negative selection	8464285
4110530	4110553	19	+	27260156	RDES	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.4942536270111772	[372]	[440,513,756,761]	7	hSpCas9	negative selection	8464286
4117616	4117639	19	-	27260156	RDES	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.8153543983380076	[42]	[3,61,6,41]	-8	hSpCas9	negative selection	8464287
4102438	4102461	19	-	27260156	RDES	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.8483145470972391	[67]	[116,140,142,166]	9	hSpCas9	negative selection	8528543
4102375	4102398	19	-	27260156	RDES	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.11098072205966225	[301]	[310,275,341,359]	-2	hSpCas9	negative selection	8528544
4117563	4117586	19	-	27260156	RDES	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.03300027662488442	[650]	[630,657,860,797]	0	hSpCas9	negative selection	8528545
4110537	4110560	19	-	27260156	PC3	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-1.8425069659302968	[10]	[0,5,0,3]	-9	hSpCas9	negative selection	8585536
4110530	4110553	19	+	27260156	PC3	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.2870757463178354	[372]	[356,428,685,420]	6	hSpCas9	negative selection	8585537
4117616	4117639	19	-	27260156	PC3	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.12960592217537714	[42]	[30,56,67,40]	3	hSpCas9	negative selection	8585538
4102438	4102461	19	-	27260156	PC3	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	1.0501338448413857	[67]	[88,162,197,140]	9	hSpCas9	negative selection	8649794
4102375	4102398	19	-	27260156	PC3	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.29339110998412077	[301]	[183,215,412,234]	-6	hSpCas9	negative selection	8649795
4117563	4117586	19	-	27260156	PC3	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.1347527063063816	[650]	[356,458,1074,722]	-3	hSpCas9	negative selection	8649796
4110537	4110560	19	-	27260156	PATU8988T	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-1.7663488552529296	[10]	[0,9,0,0]	-9	hSpCas9	negative selection	8706787
4110530	4110553	19	+	27260156	PATU8988T	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.3583552044004084	[372]	[390,594,493,372]	6	hSpCas9	negative selection	8706788
4117616	4117639	19	-	27260156	PATU8988T	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	0.72884323465812	[42]	[65,21,107,74]	9	hSpCas9	negative selection	8706789
4102438	4102461	19	-	27260156	PATU8988T	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	-0.24247130073514755	[67]	[46,54,34,87]	-4	hSpCas9	negative selection	8771045
4102375	4102398	19	-	27260156	PATU8988T	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.35691988672909297	[301]	[353,582,330,235]	6	hSpCas9	negative selection	8771046
4117563	4117586	19	-	27260156	PATU8988T	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.005073268214396465	[650]	[629,608,716,559]	0	hSpCas9	negative selection	8771047
4110537	4110560	19	-	27260156	T47D	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-0.22338752518753413	[10]	[3,14,2,21]	-5	hSpCas9	negative selection	8828038
4110530	4110553	19	+	27260156	T47D	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.6654897402810453	[372]	[775,711,574,693]	9	hSpCas9	negative selection	8828039
4117616	4117639	19	-	27260156	T47D	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.015433351757740077	[42]	[43,41,55,56]	0	hSpCas9	negative selection	8828040
4102438	4102461	19	-	27260156	T47D	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.6271535862550586	[67]	[132,127,129,96]	9	hSpCas9	negative selection	8892296
4102375	4102398	19	-	27260156	T47D	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.12580362067111228	[301]	[447,297,426,368]	2	hSpCas9	negative selection	8892297
4117563	4117586	19	-	27260156	T47D	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.050289003428561685	[650]	[737,643,897,651]	-1	hSpCas9	negative selection	8892298
4110537	4110560	19	-	27260156	SU8686	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.07736792385459879	[10]	[4,8,4,30]	1	hSpCas9	negative selection	8949289
4110530	4110553	19	+	27260156	SU8686	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.7147589010787652	[372]	[548,533,562,827]	9	hSpCas9	negative selection	8949290
4117616	4117639	19	-	27260156	SU8686	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.22808413318065401	[42]	[35,39,30,37]	-4	hSpCas9	negative selection	8949291
4102438	4102461	19	-	27260156	SU8686	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.5426455686959795	[67]	[95,91,121,80]	8	hSpCas9	negative selection	9013547
4102375	4102398	19	-	27260156	SU8686	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.09614425820255368	[301]	[208,202,257,501]	-2	hSpCas9	negative selection	9013548
4117563	4117586	19	-	27260156	SU8686	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.9012603737006228	[650]	[228,258,432,512]	-8	hSpCas9	negative selection	9013549
4110537	4110560	19	-	27260156	SKES1	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.5025148968215287	[10]	[8,0,21,25]	8	hSpCas9	negative selection	9070540
4110530	4110553	19	+	27260156	SKES1	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.4801136535638084	[372]	[516,439,637,469]	8	hSpCas9	negative selection	9070541
4117616	4117639	19	-	27260156	SKES1	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.1828109555303996	[42]	[70,16,47,18]	-4	hSpCas9	negative selection	9070542
4102438	4102461	19	-	27260156	SKES1	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.425526936914439	[67]	[109,131,72,59]	8	hSpCas9	negative selection	9134798
4102375	4102398	19	-	27260156	SKES1	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.1849117223840817	[301]	[221,290,200,332]	-4	hSpCas9	negative selection	9134799
4117563	4117586	19	-	27260156	SKES1	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.09918747937023703	[650]	[636,745,590,480]	-2	hSpCas9	negative selection	9134800
4110537	4110560	19	-	27260156	TOV112D	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-0.662797426072963	[10]	[1,28,0,0]	-8	hSpCas9	negative selection	9191791
4110530	4110553	19	+	27260156	TOV112D	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.4021944591321868	[372]	[433,724,523,346]	7	hSpCas9	negative selection	9191792
4117616	4117639	19	-	27260156	TOV112D	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-1.026425465942832	[42]	[3,15,46,14]	-9	hSpCas9	negative selection	9191793
4102438	4102461	19	-	27260156	TOV112D	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.3467132532228696	[67]	[74,127,47,103]	6	hSpCas9	negative selection	9256049
4102375	4102398	19	-	27260156	TOV112D	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.13991795432893128	[301]	[339,353,274,156]	-3	hSpCas9	negative selection	9256050
4117563	4117586	19	-	27260156	TOV112D	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.1527217682341866	[650]	[895,816,708,518]	3	hSpCas9	negative selection	9256051
4110537	4110560	19	-	27260156	TC71	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	0.05747082351714461	[10]	[0,7,5,35]	1	hSpCas9	negative selection	9313042
4110530	4110553	19	+	27260156	TC71	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.24856276940131528	[372]	[537,436,413,513]	6	hSpCas9	negative selection	9313043
4117616	4117639	19	-	27260156	TC71	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.0726585159727291	[42]	[24,41,44,64]	-2	hSpCas9	negative selection	9313044
4102438	4102461	19	-	27260156	TC71	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.5217339260997598	[67]	[96,164,67,88]	9	hSpCas9	negative selection	9377300
4102375	4102398	19	-	27260156	TC71	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	0.014568128157057547	[301]	[276,307,383,338]	0	hSpCas9	negative selection	9377301
4117563	4117586	19	-	27260156	TC71	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.1047201395374402	[650]	[800,704,738,755]	2	hSpCas9	negative selection	9377302
4110537	4110560	19	-	27260156	TC32	viability	TACGGGGCCTTCTACAGTGACGG	MAP2K2	ENSG00000126934	-0.9157994083440899	[10]	[7,0,3,9]	-9	hSpCas9	negative selection	9434293
4110530	4110553	19	+	27260156	TC32	viability	GATCTCCCCGTCACTGTAGAAGG	MAP2K2	ENSG00000126934	0.5579804645469596	[372]	[425,410,703,579]	8	hSpCas9	negative selection	9434294
4117616	4117639	19	-	27260156	TC32	viability	TCTCTGCAGGGCAAACCTGGTGG	MAP2K2	ENSG00000126934	-0.6743188430150808	[42]	[1,5,42,64]	-8	hSpCas9	negative selection	9434295
4102438	4102461	19	-	27260156	TC32	viability	CCTCTAGGACGGCGGCTCCCTGG	MAP2K2	ENSG00000126934	0.6468596779434939	[67]	[58,82,187,90]	9	hSpCas9	negative selection	9498551
4102375	4102398	19	-	27260156	TC32	viability	CCTGGGGAAAGTCAGCATCGCGG	MAP2K2	ENSG00000126934	-0.2201119093191478	[301]	[252,149,355,255]	-4	hSpCas9	negative selection	9498552
4117563	4117586	19	-	27260156	TC32	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.018991113404284332	[650]	[596,278,871,889]	0	hSpCas9	negative selection	9498553
4090688	4090711	19	-	27869803	HPAFII	viability after 27 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.38546167728007047	[411]	[233,108,NaN]	-3	hSpCas9	negative selection	9567853
4097278	4097301	19	-	27869803	HPAFII	viability after 27 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	0.8882705621814053	[716]	[958,479,NaN]	7	hSpCas9	negative selection	9567869
4099223	4099246	19	-	27869803	HPAFII	viability after 27 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.5674192836169332	[271]	[92,310,NaN]	4	hSpCas9	negative selection	9567871
4117559	4117582	19	-	27869803	HPAFII	viability after 27 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	-1.4980628508053104	[210]	[5,66,NaN]	-7	hSpCas9	negative selection	9567889
4117563	4117586	19	-	27869803	HPAFII	viability after 27 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.0775064906091929	[732]	[362,442,NaN]	0	hSpCas9	negative selection	9567890
4090688	4090711	19	-	27869803	HPAFII	viability after 15 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.4692478424615695	[411]	[436,246,NaN]	-5	hSpCas9	negative selection	9650302
4097278	4097301	19	-	27869803	HPAFII	viability after 15 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	0.3459471497997386	[716]	[1476,669,NaN]	4	hSpCas9	negative selection	9650318
4099223	4099246	19	-	27869803	HPAFII	viability after 15 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.7480174925898428	[271]	[395,549,NaN]	8	hSpCas9	negative selection	9650320
4117559	4117582	19	-	27869803	HPAFII	viability after 15 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	-1.0847742260703335	[210]	[72,127,NaN]	-8	hSpCas9	negative selection	9650338
4117563	4117586	19	-	27869803	HPAFII	viability after 15 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.2097771499185841	[732]	[867,564,NaN]	-2	hSpCas9	negative selection	9650339
4090688	4090711	19	-	27869803	ASPC1	viability after 36 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.021148248959724447	[1023]	[355,365,334]	0	hSpCas9	negative selection	9732751
4097278	4097301	19	-	27869803	ASPC1	viability after 36 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	0.5391120708067811	[1750]	[796,1130,749]	5	hSpCas9	negative selection	9732767
4099223	4099246	19	-	27869803	ASPC1	viability after 36 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.4012956759584546	[881]	[350,396,448]	4	hSpCas9	negative selection	9732769
4117559	4117582	19	-	27869803	ASPC1	viability after 36 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	-1.9506819067017511	[412]	[45,31,34]	-9	hSpCas9	negative selection	9732787
4117563	4117586	19	-	27869803	ASPC1	viability after 36 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.26127942232526824	[1416]	[437,449,360]	-3	hSpCas9	negative selection	9732788
4090688	4090711	19	-	27869803	PATU8988S	viability after 35 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	0.11128584891044546	[903]	[297,488,NaN]	1	hSpCas9	negative selection	9815200
4097278	4097301	19	-	27869803	PATU8988S	viability after 35 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	0.04177040399054621	[1566]	[714,583,NaN]	0	hSpCas9	negative selection	9815216
4099223	4099246	19	-	27869803	PATU8988S	viability after 35 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.34495511330242307	[691]	[346,360,NaN]	4	hSpCas9	negative selection	9815218
4117559	4117582	19	-	27869803	PATU8988S	viability after 35 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	-0.17143927278816862	[357]	[140,114,NaN]	-2	hSpCas9	negative selection	9815236
4117563	4117586	19	-	27869803	PATU8988S	viability after 35 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.25653134655441123	[1164]	[565,554,NaN]	3	hSpCas9	negative selection	9815237
4090688	4090711	19	-	27869803	PATU8988S	viability after 31 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.10905770891330835	[903]	[236,457,NaN]	-1	hSpCas9	negative selection	9897649
4097278	4097301	19	-	27869803	PATU8988S	viability after 31 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	0.09956177807925748	[1566]	[639,706,NaN]	1	hSpCas9	negative selection	9897665
4099223	4099246	19	-	27869803	PATU8988S	viability after 31 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.01978943134400296	[691]	[189,393,NaN]	0	hSpCas9	negative selection	9897667
4117559	4117582	19	-	27869803	PATU8988S	viability after 31 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	-0.044279756609645005	[357]	[115,166,NaN]	0	hSpCas9	negative selection	9897685
4117563	4117586	19	-	27869803	PATU8988S	viability after 31 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.0883890303758641	[1164]	[525,452,NaN]	1	hSpCas9	negative selection	9897686
4090688	4090711	19	-	27869803	HPAFII	viability after 35 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.7150090596807525	[411]	[135,116,NaN]	-4	hSpCas9	negative selection	9980098
4097278	4097301	19	-	27869803	HPAFII	viability after 35 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	1.0105795758505938	[716]	[981,448,NaN]	6	hSpCas9	negative selection	9980114
4099223	4099246	19	-	27869803	HPAFII	viability after 35 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.535513627065484	[271]	[81,331,NaN]	3	hSpCas9	negative selection	9980116
4117559	4117582	19	-	27869803	HPAFII	viability after 35 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	-3.006471146878237	[210]	[9,16,NaN]	-8	hSpCas9	negative selection	9980134
4117563	4117586	19	-	27869803	HPAFII	viability after 35 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.12029983493541829	[732]	[392,414,NaN]	0	hSpCas9	negative selection	9980135
4090688	4090711	19	-	27869803	HPAFII	viability after 31 days	AGAACCACACCTTCATCAAGCGG	MAP2K2	ENSG00000126934	-0.16263241261444694	[411]	[196,216,NaN]	-1	hSpCas9	negative selection	10062547
4097278	4097301	19	-	27869803	HPAFII	viability after 31 days	CCTGGACTATATTGTGAACGAGG	MAP2K2	ENSG00000126934	0.9163530657169581	[716]	[936,565,NaN]	7	hSpCas9	negative selection	10062563
4099223	4099246	19	-	27869803	HPAFII	viability after 31 days	ACAGCATCTCGCCTCGGCCGAGG	MAP2K2	ENSG00000126934	0.5813723162534864	[271]	[69,400,NaN]	4	hSpCas9	negative selection	10062565
4117559	4117582	19	-	27869803	HPAFII	viability after 31 days	CGAGCAGCAGAAGAAGCGGCTGG	MAP2K2	ENSG00000126934	-1.3659593147979652	[210]	[66,22,NaN]	-7	hSpCas9	negative selection	10062583
4117563	4117586	19	-	27869803	HPAFII	viability after 31 days	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.18465661648452558	[732]	[434,502,NaN]	1	hSpCas9	negative selection	10062584
4123793	4123816	19	-	28162770	P31FUJ	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	-0.3516796002662987	[176]	[162]	-3	hSpCas9	negative selection	10188657
4117481	4117504	19	-	28162770	P31FUJ	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.5416380951704904	[227]	[389]	6	hSpCas9	negative selection	10188658
4101228	4101251	19	-	28162770	P31FUJ	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	-0.6896598793878496	[419]	[305]	-5	hSpCas9	negative selection	10188659
4099316	4099339	19	+	28162770	P31FUJ	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	-1.222886735549296	[144]	[72]	-7	hSpCas9	negative selection	10188660
4117418	4117441	19	-	28162770	P31FUJ	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	0.7313970741577747	[101]	[198]	8	hSpCas9	negative selection	10188661
4102391	4102414	19	-	28162770	P31FUJ	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	-1.2328022044143783	[41]	[20]	-7	hSpCas9	negative selection	10188662
4097314	4097337	19	-	28162770	P31FUJ	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	-0.5754888594685383	[174]	[137]	-5	hSpCas9	negative selection	10188663
4097297	4097320	19	+	28162770	P31FUJ	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	-0.02809206063848413	[386]	[445]	0	hSpCas9	negative selection	10188664
4094479	4094502	19	-	28162770	P31FUJ	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	-0.4572337710244251	[471]	[403]	-4	hSpCas9	negative selection	10188665
4117563	4117586	19	-	28162770	P31FUJ	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.2869326735311584	[278]	[399]	3	hSpCas9	negative selection	10188666
4123793	4123816	19	-	28162770	TF1	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	NaN	[NaN]	[142]	1	hSpCas9	negative selection	10358023
4117481	4117504	19	-	28162770	TF1	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	NaN	[NaN]	[201]	1	hSpCas9	negative selection	10358024
4101228	4101251	19	-	28162770	TF1	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	NaN	[NaN]	[539]	1	hSpCas9	negative selection	10358025
4099316	4099339	19	+	28162770	TF1	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	NaN	[NaN]	[94]	1	hSpCas9	negative selection	10358026
4117418	4117441	19	-	28162770	TF1	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10358027
4102391	4102414	19	-	28162770	TF1	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	NaN	[NaN]	[19]	1	hSpCas9	negative selection	10358028
4097314	4097337	19	-	28162770	TF1	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	NaN	[NaN]	[152]	1	hSpCas9	negative selection	10358029
4097297	4097320	19	+	28162770	TF1	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	NaN	[NaN]	[276]	1	hSpCas9	negative selection	10358030
4094479	4094502	19	-	28162770	TF1	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	NaN	[NaN]	[341]	1	hSpCas9	negative selection	10358031
4117563	4117586	19	-	28162770	TF1	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	NaN	[NaN]	[204]	1	hSpCas9	negative selection	10358032
4123793	4123816	19	-	28162770	SKM1	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	-1.229177079527879	[60]	[45]	-7	hSpCas9	negative selection	10527389
4117481	4117504	19	-	28162770	SKM1	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.23888054412501686	[57]	[120]	2	hSpCas9	negative selection	10527390
4101228	4101251	19	-	28162770	SKM1	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	-0.11212976473807412	[128]	[210]	-1	hSpCas9	negative selection	10527391
4099316	4099339	19	+	28162770	SKM1	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	-1.8861320354417213	[45]	[21]	-8	hSpCas9	negative selection	10527392
4117418	4117441	19	-	28162770	SKM1	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	-0.789580220329628	[43]	[44]	-5	hSpCas9	negative selection	10527393
4102391	4102414	19	-	28162770	SKM1	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	0.5930358012568386	[11]	[31]	6	hSpCas9	negative selection	10527394
4097314	4097337	19	-	28162770	SKM1	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	-0.5489832036155895	[47]	[57]	-4	hSpCas9	negative selection	10527395
4097297	4097320	19	+	28162770	SKM1	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	0.18666316310512188	[82]	[166]	1	hSpCas9	negative selection	10527396
4094479	4094502	19	-	28162770	SKM1	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	-0.6414294523801848	[89]	[101]	-5	hSpCas9	negative selection	10527397
4117563	4117586	19	-	28162770	SKM1	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	2.2399260511211962	[56]	[475]	9	hSpCas9	negative selection	10527398
4123793	4123816	19	-	28162770	SKM1	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	-1.229177079527879	[60]	[45]	-7	hSpCas9	negative selection	10696755
4117481	4117504	19	-	28162770	SKM1	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.23888054412501686	[57]	[120]	2	hSpCas9	negative selection	10696756
4101228	4101251	19	-	28162770	SKM1	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	-0.11212976473807412	[128]	[210]	-1	hSpCas9	negative selection	10696757
4099316	4099339	19	+	28162770	SKM1	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	-1.8861320354417213	[45]	[21]	-8	hSpCas9	negative selection	10696758
4117418	4117441	19	-	28162770	SKM1	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	-0.789580220329628	[43]	[44]	-5	hSpCas9	negative selection	10696759
4102391	4102414	19	-	28162770	SKM1	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	0.5930358012568386	[11]	[31]	6	hSpCas9	negative selection	10696760
4097314	4097337	19	-	28162770	SKM1	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	-0.5489832036155895	[47]	[57]	-4	hSpCas9	negative selection	10696761
4097297	4097320	19	+	28162770	SKM1	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	0.18666316310512188	[82]	[166]	1	hSpCas9	negative selection	10696762
4094479	4094502	19	-	28162770	SKM1	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	-0.6414294523801848	[89]	[101]	-5	hSpCas9	negative selection	10696763
4117563	4117586	19	-	28162770	SKM1	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	2.2399260511211962	[56]	[475]	9	hSpCas9	negative selection	10696764
4123793	4123816	19	-	28162770	PL21	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	-0.22019218445903677	[181]	[67]	-1	hSpCas9	negative selection	10866121
4117481	4117504	19	-	28162770	PL21	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.3720922972786149	[157]	[88]	3	hSpCas9	negative selection	10866122
4101228	4101251	19	-	28162770	PL21	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	1.213718020989861	[422]	[426]	8	hSpCas9	negative selection	10866123
4099316	4099339	19	+	28162770	PL21	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	-2.86287018303648	[116]	[6]	-9	hSpCas9	negative selection	10866124
4117418	4117441	19	-	28162770	PL21	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	-0.5368259796768862	[109]	[32]	-4	hSpCas9	negative selection	10866125
4102391	4102414	19	-	28162770	PL21	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	-3.8873232267610196	[33]	[0]	-9	hSpCas9	negative selection	10866126
4097314	4097337	19	-	28162770	PL21	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	-1.031590671426464	[154]	[32]	-6	hSpCas9	negative selection	10866127
4097297	4097320	19	+	28162770	PL21	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	0.47395769603635507	[310]	[187]	4	hSpCas9	negative selection	10866128
4094479	4094502	19	-	28162770	PL21	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	-0.43681752387009737	[338]	[108]	-3	hSpCas9	negative selection	10866129
4117563	4117586	19	-	28162770	PL21	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	1.380711860131141	[164]	[186]	9	hSpCas9	negative selection	10866130
4123793	4123816	19	-	28162770	P31FUJ	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	-0.3516796002662987	[176]	[162]	-3	hSpCas9	negative selection	11035487
4117481	4117504	19	-	28162770	P31FUJ	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.5416380951704904	[227]	[389]	6	hSpCas9	negative selection	11035488
4101228	4101251	19	-	28162770	P31FUJ	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	-0.6896598793878496	[419]	[305]	-5	hSpCas9	negative selection	11035489
4099316	4099339	19	+	28162770	P31FUJ	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	-1.222886735549296	[144]	[72]	-7	hSpCas9	negative selection	11035490
4117418	4117441	19	-	28162770	P31FUJ	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	0.7313970741577747	[101]	[198]	8	hSpCas9	negative selection	11035491
4102391	4102414	19	-	28162770	P31FUJ	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	-1.2328022044143783	[41]	[20]	-7	hSpCas9	negative selection	11035492
4097314	4097337	19	-	28162770	P31FUJ	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	-0.5754888594685383	[174]	[137]	-5	hSpCas9	negative selection	11035493
4097297	4097320	19	+	28162770	P31FUJ	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	-0.02809206063848413	[386]	[445]	0	hSpCas9	negative selection	11035494
4094479	4094502	19	-	28162770	P31FUJ	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	-0.4572337710244251	[471]	[403]	-4	hSpCas9	negative selection	11035495
4117563	4117586	19	-	28162770	P31FUJ	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.2869326735311584	[278]	[399]	3	hSpCas9	negative selection	11035496
4123793	4123816	19	-	28162770	OCIAML5	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	0.9299327769167128	[40]	[140]	7	hSpCas9	negative selection	11204853
4117481	4117504	19	-	28162770	OCIAML5	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.8691317074438927	[137]	[454]	7	hSpCas9	negative selection	11204854
4101228	4101251	19	-	28162770	OCIAML5	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	0.18675267802653128	[219]	[451]	1	hSpCas9	negative selection	11204855
4099316	4099339	19	+	28162770	OCIAML5	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	0.18675267802653106	[54]	[112]	1	hSpCas9	negative selection	11204856
4117418	4117441	19	-	28162770	OCIAML5	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	0.35438430660342934	[25]	[59]	3	hSpCas9	negative selection	11204857
4102391	4102414	19	-	28162770	OCIAML5	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	-1.1891015581415676	[23]	[18]	-6	hSpCas9	negative selection	11204858
4097314	4097337	19	-	28162770	OCIAML5	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	0.5105035085207112	[90]	[233]	4	hSpCas9	negative selection	11204859
4097297	4097320	19	+	28162770	OCIAML5	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	-1.0080168488257097	[243]	[218]	-6	hSpCas9	negative selection	11204860
4094479	4094502	19	-	28162770	OCIAML5	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	0.5757301591301883	[196]	[529]	5	hSpCas9	negative selection	11204861
4117563	4117586	19	-	28162770	OCIAML5	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.5971191508266922	[166]	[455]	5	hSpCas9	negative selection	11204862
4123793	4123816	19	-	28162770	EOL1	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	-0.11372224535718284	[381]	[185]	-1	hSpCas9	negative selection	11374219
4117481	4117504	19	-	28162770	EOL1	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.9972168392687671	[270]	[284]	8	hSpCas9	negative selection	11374220
4101228	4101251	19	-	28162770	EOL1	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	0.6553611387551457	[751]	[623]	6	hSpCas9	negative selection	11374221
4099316	4099339	19	+	28162770	EOL1	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	-0.777370875496471	[243]	[74]	-5	hSpCas9	negative selection	11374222
4117418	4117441	19	-	28162770	EOL1	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	0.24647586645789696	[231]	[144]	2	hSpCas9	negative selection	11374223
4102391	4102414	19	-	28162770	EOL1	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	-0.33483885724811513	[78]	[32]	-3	hSpCas9	negative selection	11374224
4097314	4097337	19	-	28162770	EOL1	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	-1.249281684327694	[184]	[40]	-7	hSpCas9	negative selection	11374225
4097297	4097320	19	+	28162770	EOL1	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	-0.17978888824420117	[343]	[159]	-1	hSpCas9	negative selection	11374226
4094479	4094502	19	-	28162770	EOL1	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	0.0668003545282923	[385]	[212]	0	hSpCas9	negative selection	11374227
4117563	4117586	19	-	28162770	EOL1	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-1.148701210460104	[302]	[71]	-6	hSpCas9	negative selection	11374228
4123793	4123816	19	-	28162770	MOLM13	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	-0.226765407763663	[279]	[172]	-1	hSpCas9	negative selection	11543585
4117481	4117504	19	-	28162770	MOLM13	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	1.5128018034201531	[252]	[521]	9	hSpCas9	negative selection	11543586
4101228	4101251	19	-	28162770	MOLM13	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	0.9113051708885163	[666]	[906]	7	hSpCas9	negative selection	11543587
4099316	4099339	19	+	28162770	MOLM13	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	-0.12091518547097169	[187]	[124]	0	hSpCas9	negative selection	11543588
4117418	4117441	19	-	28162770	MOLM13	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	-1.4679802810357052	[175]	[45]	-6	hSpCas9	negative selection	11543589
4102391	4102414	19	-	28162770	MOLM13	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	0.843398516636785	[36]	[47]	6	hSpCas9	negative selection	11543590
4097314	4097337	19	-	28162770	MOLM13	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	0.6737936800924579	[175]	[202]	5	hSpCas9	negative selection	11543591
4097297	4097320	19	+	28162770	MOLM13	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	-0.1906762092165752	[381]	[241]	-1	hSpCas9	negative selection	11543592
4094479	4094502	19	-	28162770	MOLM13	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	-0.5739307941500481	[524]	[254]	-3	hSpCas9	negative selection	11543593
4117563	4117586	19	-	28162770	MOLM13	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.8615462500117249	[288]	[114]	-5	hSpCas9	negative selection	11543594
4123793	4123816	19	-	28162770	HEL	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	0.12078612880500128	[279]	[194]	1	hSpCas9	negative selection	11712951
4117481	4117504	19	-	28162770	HEL	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.8945459824108966	[214]	[255]	7	hSpCas9	negative selection	11712952
4101228	4101251	19	-	28162770	HEL	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	0.9740720745482656	[580]	[730]	8	hSpCas9	negative selection	11712953
4099316	4099339	19	+	28162770	HEL	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	-0.7666521041373447	[169]	[63]	-5	hSpCas9	negative selection	11712954
4117418	4117441	19	-	28162770	HEL	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	0.6882534912527258	[155]	[160]	6	hSpCas9	negative selection	11712955
4102391	4102414	19	-	28162770	HEL	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	-1.7495785907784032	[41]	[7]	-7	hSpCas9	negative selection	11712956
4097314	4097337	19	-	28162770	HEL	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	0.560276671808384	[143]	[135]	5	hSpCas9	negative selection	11712957
4097297	4097320	19	+	28162770	HEL	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	0.7686612719753121	[306]	[334]	6	hSpCas9	negative selection	11712958
4094479	4094502	19	-	28162770	HEL	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	-0.23393287419229813	[436]	[237]	-2	hSpCas9	negative selection	11712959
4117563	4117586	19	-	28162770	HEL	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.6911018535617561	[263]	[272]	6	hSpCas9	negative selection	11712960
4123793	4123816	19	-	28162770	MV411	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	-1.4514811392354667	[236]	[72]	-7	hSpCas9	negative selection	11882317
4117481	4117504	19	-	28162770	MV411	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.32886515012662154	[154]	[163]	3	hSpCas9	negative selection	11882318
4101228	4101251	19	-	28162770	MV411	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	-0.058964364360538424	[438]	[354]	0	hSpCas9	negative selection	11882319
4099316	4099339	19	+	28162770	MV411	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	-1.3864345504193274	[179]	[57]	-7	hSpCas9	negative selection	11882320
4117418	4117441	19	-	28162770	MV411	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	0.458941655976487	[113]	[131]	4	hSpCas9	negative selection	11882321
4102391	4102414	19	-	28162770	MV411	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	0.049498173170866355	[38]	[33]	0	hSpCas9	negative selection	11882322
4097314	4097337	19	-	28162770	MV411	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	0.5015388318465615	[134]	[160]	4	hSpCas9	negative selection	11882323
4097297	4097320	19	+	28162770	MV411	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	-0.5268496695891655	[247]	[144]	-4	hSpCas9	negative selection	11882324
4094479	4094502	19	-	28162770	MV411	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	-0.6360484404907996	[320]	[173]	-4	hSpCas9	negative selection	11882325
4117563	4117586	19	-	28162770	MV411	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-0.3132774036917037	[176]	[119]	-2	hSpCas9	negative selection	11882326
4123793	4123816	19	-	28162770	MONOMAC1	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	-1.310693628855121	[131]	[60]	-7	hSpCas9	negative selection	12051683
4117481	4117504	19	-	28162770	MONOMAC1	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.5034028710815386	[119]	[194]	5	hSpCas9	negative selection	12051684
4101228	4101251	19	-	28162770	MONOMAC1	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	0.11258435237619557	[258]	[320]	1	hSpCas9	negative selection	12051685
4099316	4099339	19	+	28162770	MONOMAC1	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	-0.06664020980387875	[73]	[80]	0	hSpCas9	negative selection	12051686
4117418	4117441	19	-	28162770	MONOMAC1	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	0.9667879548463407	[78]	[176]	8	hSpCas9	negative selection	12051687
4102391	4102414	19	-	28162770	MONOMAC1	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	-0.7564642556735723	[27]	[18]	-6	hSpCas9	negative selection	12051688
4097314	4097337	19	-	28162770	MONOMAC1	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	-1.0853914912306446	[86]	[46]	-7	hSpCas9	negative selection	12051689
4097297	4097320	19	+	28162770	MONOMAC1	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	0.32950896743628044	[167]	[241]	3	hSpCas9	negative selection	12051690
4094479	4094502	19	-	28162770	MONOMAC1	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	0.009892456889089907	[200]	[231]	0	hSpCas9	negative selection	12051691
4117563	4117586	19	-	28162770	MONOMAC1	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	0.05706443400423228	[134]	[160]	0	hSpCas9	negative selection	12051692
4123793	4123816	19	-	28162770	OCIAML2	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	-1.8331999046268692	[26]	[41]	-8	hSpCas9	negative selection	12221049
4117481	4117504	19	-	28162770	OCIAML2	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	-1.3496144242807953	[39]	[86]	-7	hSpCas9	negative selection	12221050
4101228	4101251	19	-	28162770	OCIAML2	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	-1.9878477193274833	[77]	[108]	-8	hSpCas9	negative selection	12221051
4099316	4099339	19	+	28162770	OCIAML2	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	-7.680083190871112	[36]	[0]	-9	hSpCas9	negative selection	12221052
4117418	4117441	19	-	28162770	OCIAML2	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	-3.965394516991739	[30]	[10]	-9	hSpCas9	negative selection	12221053
4102391	4102414	19	-	28162770	OCIAML2	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	-2.6930222465786096	[6]	[5]	-9	hSpCas9	negative selection	12221054
4097314	4097337	19	-	28162770	OCIAML2	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	-1.9497976619407202	[22]	[32]	-8	hSpCas9	negative selection	12221055
4097297	4097320	19	+	28162770	OCIAML2	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	-2.3450989431583023	[43]	[47]	-8	hSpCas9	negative selection	12221056
4094479	4094502	19	-	28162770	OCIAML2	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	-4.5410191531335595	[62]	[14]	-9	hSpCas9	negative selection	12221057
4117563	4117586	19	-	28162770	OCIAML2	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	-1.2153727700000867	[30]	[73]	-7	hSpCas9	negative selection	12221058
4123793	4123816	19	-	28162770	OCIAML3	viability	GGCCCATCCCCTACCAGCGAGGG	MAP2K2	ENSG00000126934	-0.3309732344903693	[44]	[107]	-3	hSpCas9	negative selection	12390415
4117481	4117504	19	-	28162770	OCIAML3	viability	AAGGATCTCAGAGCTGGGCGCGG	MAP2K2	ENSG00000126934	0.9503128758996471	[47]	[279]	8	hSpCas9	negative selection	12390416
4101228	4101251	19	-	28162770	OCIAML3	viability	AAGCACCAGATCATGCACCGAGG	MAP2K2	ENSG00000126934	0.24572595519964668	[106]	[382]	2	hSpCas9	negative selection	12390417
4099316	4099339	19	+	28162770	OCIAML3	viability	GGGGATGGGGTACCTTCCGACGG	MAP2K2	ENSG00000126934	0.3706592865635562	[30]	[120]	3	hSpCas9	negative selection	12390418
4117418	4117441	19	-	28162770	OCIAML3	viability	GGGCCTCATCATGGCCAGGAAGG	MAP2K2	ENSG00000126934	1.8230776876035393	[21]	[234]	9	hSpCas9	negative selection	12390419
4102391	4102414	19	-	28162770	OCIAML3	viability	GGATTCCCGAGGAGATCCTGGGG	MAP2K2	ENSG00000126934	-1.7866527182665588	[7]	[6]	-8	hSpCas9	negative selection	12390420
4097314	4097337	19	-	28162770	OCIAML3	viability	GATGGATAGCCGGCCTGCCATGG	MAP2K2	ENSG00000126934	-0.9208179565912715	[36]	[58]	-6	hSpCas9	negative selection	12390421
4097297	4097320	19	+	28162770	OCIAML3	viability	CAGGAGTTCAAAGATGGCCATGG	MAP2K2	ENSG00000126934	0.622803748748985	[73]	[343]	5	hSpCas9	negative selection	12390422
4094479	4094502	19	-	28162770	OCIAML3	viability	CAGCCTCATCAAGAACCCAGCGG	MAP2K2	ENSG00000126934	0.32266397607694064	[97]	[369]	3	hSpCas9	negative selection	12390423
4117563	4117586	19	-	28162770	OCIAML3	viability	TTGACGAGCAGCAGAAGAAGCGG	MAP2K2	ENSG00000126934	1.5638445288175742	[39]	[356]	9	hSpCas9	negative selection	12390424