Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 4137
• Symbol: MAPT
• Description: microtubule associated protein tau

DataSource: http://genomecrispr.dkfz.de/#!/results/MAPT

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
45962362	45962385	17	+	26472758	Jiyoye	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	-0.5103624583021535	[50]	[26]	-4	hSpCas9	negative selection	96448
45973987	45974010	CHR_HSCHR17_2_CTG5	+	26472758	Jiyoye	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000277956	-0.5103624583021535	[50]	[26]	-4	hSpCas9	negative selection	96449
46135453	46135476	CHR_HSCHR17_1_CTG5	-	26472758	Jiyoye	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000276155	-0.5103624583021535	[50]	[26]	-4	hSpCas9	negative selection	96450
46008247	46008270	CHR_HSCHR17_2_CTG5	+	26472758	Jiyoye	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000277956	-0.8902105291186975	[203]	[82]	-6	hSpCas9	negative selection	96451
45996631	45996654	17	+	26472758	Jiyoye	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	-0.8902105291186975	[203]	[82]	-6	hSpCas9	negative selection	96452
46101234	46101257	CHR_HSCHR17_1_CTG5	-	26472758	Jiyoye	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000276155	-0.8902105291186975	[203]	[82]	-6	hSpCas9	negative selection	96453
45990034	45990057	CHR_HSCHR17_2_CTG5	+	26472758	Jiyoye	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000277956	0.7668455703847867	[165]	[212]	5	hSpCas9	negative selection	96454
45978419	45978442	17	+	26472758	Jiyoye	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.7668455703847867	[165]	[212]	5	hSpCas9	negative selection	96455
46119505	46119528	CHR_HSCHR17_1_CTG5	-	26472758	Jiyoye	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000276155	0.7668455703847867	[165]	[212]	5	hSpCas9	negative selection	96456
46135466	46135489	CHR_HSCHR17_1_CTG5	+	26472758	Jiyoye	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000276155	-0.5490083862016368	[226]	[116]	-4	hSpCas9	negative selection	96457
45962349	45962372	17	-	26472758	Jiyoye	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	-0.5490083862016368	[226]	[116]	-4	hSpCas9	negative selection	96458
45973974	45973997	CHR_HSCHR17_2_CTG5	-	26472758	Jiyoye	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000277956	-0.5490083862016368	[226]	[116]	-4	hSpCas9	negative selection	96459
45974065	45974088	CHR_HSCHR17_2_CTG5	+	26472758	Jiyoye	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000277956	0.4306343543298623	[121]	[123]	3	hSpCas9	negative selection	96460
45962440	45962463	17	+	26472758	Jiyoye	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	0.4306343543298623	[121]	[123]	3	hSpCas9	negative selection	96461
46135375	46135398	CHR_HSCHR17_1_CTG5	-	26472758	Jiyoye	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000276155	0.4306343543298623	[121]	[123]	3	hSpCas9	negative selection	96462
46106391	46106414	CHR_HSCHR17_1_CTG5	-	26472758	Jiyoye	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000276155	1.1256615550644193	[109]	[180]	7	hSpCas9	negative selection	96463
45991473	45991496	17	+	26472758	Jiyoye	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	1.1256615550644193	[109]	[180]	7	hSpCas9	negative selection	96464
46003089	46003112	CHR_HSCHR17_2_CTG5	+	26472758	Jiyoye	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000277956	1.1256615550644193	[109]	[180]	7	hSpCas9	negative selection	96465
46008013	46008036	CHR_HSCHR17_2_CTG5	+	26472758	Jiyoye	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000277956	0.0011830218300366013	[211]	[159]	0	hSpCas9	negative selection	96466
45996397	45996420	17	+	26472758	Jiyoye	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	0.0011830218300366013	[211]	[159]	0	hSpCas9	negative selection	96467
46101468	46101491	CHR_HSCHR17_1_CTG5	-	26472758	Jiyoye	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000276155	0.0011830218300366013	[211]	[159]	0	hSpCas9	negative selection	96468
46008023	46008046	CHR_HSCHR17_2_CTG5	+	26472758	Jiyoye	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000277956	-1.100619258692823	[90]	[31]	-6	hSpCas9	negative selection	96469
45996407	45996430	17	+	26472758	Jiyoye	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	-1.100619258692823	[90]	[31]	-6	hSpCas9	negative selection	96470
46101458	46101481	CHR_HSCHR17_1_CTG5	-	26472758	Jiyoye	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000276155	-1.100619258692823	[90]	[31]	-6	hSpCas9	negative selection	96471
45996477	45996500	17	-	26472758	Jiyoye	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-0.9464615731088268	[68]	[26]	-6	hSpCas9	negative selection	96472
46008093	46008116	CHR_HSCHR17_2_CTG5	-	26472758	Jiyoye	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000277956	-0.9464615731088268	[68]	[26]	-6	hSpCas9	negative selection	96473
46101388	46101411	CHR_HSCHR17_1_CTG5	+	26472758	Jiyoye	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000276155	-0.9464615731088268	[68]	[26]	-6	hSpCas9	negative selection	96474
45996505	45996528	17	+	26472758	Jiyoye	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-1.4408215250490766	[125]	[34]	-7	hSpCas9	negative selection	96475
46008121	46008144	CHR_HSCHR17_2_CTG5	+	26472758	Jiyoye	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000277956	-1.4408215250490766	[125]	[34]	-7	hSpCas9	negative selection	96476
46010995	46011018	CHR_HSCHR17_2_CTG5	-	26472758	Jiyoye	viability	TGAATCATCCACTCACACAGAGG	MAPT	ENSG00000277956	-0.28834549436298146	[182]	[112]	-2	hSpCas9	negative selection	157783
46010964	46010987	CHR_HSCHR17_2_CTG5	-	26472758	Jiyoye	viability	AATTAACCCCGCATTCAATGAGG	MAPT	ENSG00000277956	0.24532450210447632	[244]	[218]	1	hSpCas9	negative selection	157785
46011071	46011094	CHR_HSCHR17_2_CTG5	-	26472758	Jiyoye	viability	GCCAACCTCAGATGAACTCAGGG	MAPT	ENSG00000277956	1.5356499394546823	[101]	[222]	8	hSpCas9	negative selection	157789
46010887	46010910	CHR_HSCHR17_2_CTG5	+	26472758	Jiyoye	viability	GTCTGGGCCATGAGTGAGGGTGG	MAPT	ENSG00000277956	2.9921378822270293	[0]	[5]	9	hSpCas9	negative selection	157791
46010957	46010980	CHR_HSCHR17_2_CTG5	+	26472758	Jiyoye	viability	GGCCGGCCCTCATTGAATGCGGG	MAPT	ENSG00000277956	-0.6136832233917908	[208]	[102]	-4	hSpCas9	negative selection	157794
46011030	46011053	CHR_HSCHR17_2_CTG5	+	26472758	Jiyoye	viability	CAGAACCCTCAGCTTAGCATGGG	MAPT	ENSG00000277956	1.9295068939566258	[101]	[292]	8	hSpCas9	negative selection	157798
46011084	46011107	CHR_HSCHR17_2_CTG5	+	26472758	Jiyoye	viability	TGAGGTTGGCTTGGAAGGTGTGG	MAPT	ENSG00000277956	1.1831351072879432	[72]	[124]	7	hSpCas9	negative selection	157800
46011189	46011212	CHR_HSCHR17_2_CTG5	-	26472758	Jiyoye	viability	GACAGTTCTGGCCCTGAAAGGGG	MAPT	ENSG00000277956	0.5313547927266034	[88]	[96]	4	hSpCas9	negative selection	157804
46011211	46011234	CHR_HSCHR17_2_CTG5	-	26472758	Jiyoye	viability	AGGGCAGCTGCAGGGTGGGAGGG	MAPT	ENSG00000277956	-2.9913739949844014	[115]	[10]	-9	hSpCas9	negative selection	157807
46011229	46011252	CHR_HSCHR17_2_CTG5	+	26472758	Jiyoye	viability	GCCCTGCCTCTGCCCATGAGGGG	MAPT	ENSG00000277956	-0.5508693020527482	[304]	[156]	-4	hSpCas9	negative selection	157810
45962362	45962385	17	+	26472758	KBM7	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	0.17698781492268845	[221,129]	[147,40]	1	hSpCas9	negative selection	287566
45973987	45974010	CHR_HSCHR17_2_CTG5	+	26472758	KBM7	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000277956	0.17698781492268845	[221,129]	[147,40]	1	hSpCas9	negative selection	287567
46135453	46135476	CHR_HSCHR17_1_CTG5	-	26472758	KBM7	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000276155	0.17698781492268845	[221,129]	[147,40]	1	hSpCas9	negative selection	287568
46008247	46008270	CHR_HSCHR17_2_CTG5	+	26472758	KBM7	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000277956	0.4035899374558396	[730,640]	[380,465]	4	hSpCas9	negative selection	287569
45996631	45996654	17	+	26472758	KBM7	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	0.4035899374558396	[730,640]	[380,465]	4	hSpCas9	negative selection	287570
46101234	46101257	CHR_HSCHR17_1_CTG5	-	26472758	KBM7	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000276155	0.4035899374558396	[730,640]	[380,465]	4	hSpCas9	negative selection	287571
45990034	45990057	CHR_HSCHR17_2_CTG5	+	26472758	KBM7	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000277956	0.5278778703159132	[674,632]	[357,520]	6	hSpCas9	negative selection	287572
45978419	45978442	17	+	26472758	KBM7	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.5278778703159132	[674,632]	[357,520]	6	hSpCas9	negative selection	287573
46119505	46119528	CHR_HSCHR17_1_CTG5	-	26472758	KBM7	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000276155	0.5278778703159132	[674,632]	[357,520]	6	hSpCas9	negative selection	287574
46135466	46135489	CHR_HSCHR17_1_CTG5	+	26472758	KBM7	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000276155	-0.07680471674230915	[812,656]	[368,286]	0	hSpCas9	negative selection	287575
45962349	45962372	17	-	26472758	KBM7	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	-0.07680471674230915	[812,656]	[368,286]	0	hSpCas9	negative selection	287576
45973974	45973997	CHR_HSCHR17_2_CTG5	-	26472758	KBM7	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000277956	-0.07680471674230915	[812,656]	[368,286]	0	hSpCas9	negative selection	287577
45974065	45974088	CHR_HSCHR17_2_CTG5	+	26472758	KBM7	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000277956	0.6583712988174174	[748,446]	[519,357]	7	hSpCas9	negative selection	287578
45962440	45962463	17	+	26472758	KBM7	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	0.6583712988174174	[748,446]	[519,357]	7	hSpCas9	negative selection	287579
46135375	46135398	CHR_HSCHR17_1_CTG5	-	26472758	KBM7	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000276155	0.6583712988174174	[748,446]	[519,357]	7	hSpCas9	negative selection	287580
46106391	46106414	CHR_HSCHR17_1_CTG5	-	26472758	KBM7	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000276155	0.9591937272439301	[578,461]	[497,449]	9	hSpCas9	negative selection	287581
45991473	45991496	17	+	26472758	KBM7	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.9591937272439301	[578,461]	[497,449]	9	hSpCas9	negative selection	287582
46003089	46003112	CHR_HSCHR17_2_CTG5	+	26472758	KBM7	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000277956	0.9591937272439301	[578,461]	[497,449]	9	hSpCas9	negative selection	287583
46008013	46008036	CHR_HSCHR17_2_CTG5	+	26472758	KBM7	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000277956	-0.05230005416778227	[1000,686]	[267,474]	0	hSpCas9	negative selection	287584
45996397	45996420	17	+	26472758	KBM7	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	-0.05230005416778227	[1000,686]	[267,474]	0	hSpCas9	negative selection	287585
46101468	46101491	CHR_HSCHR17_1_CTG5	-	26472758	KBM7	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000276155	-0.05230005416778227	[1000,686]	[267,474]	0	hSpCas9	negative selection	287586
46008023	46008046	CHR_HSCHR17_2_CTG5	+	26472758	KBM7	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000277956	0.053146123774714726	[336,286]	[147,154]	0	hSpCas9	negative selection	287587
45996407	45996430	17	+	26472758	KBM7	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	0.053146123774714726	[336,286]	[147,154]	0	hSpCas9	negative selection	287588
46101458	46101481	CHR_HSCHR17_1_CTG5	-	26472758	KBM7	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000276155	0.053146123774714726	[336,286]	[147,154]	0	hSpCas9	negative selection	287589
45996477	45996500	17	-	26472758	KBM7	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-1.7321249039226359	[468,418]	[47,75]	-8	hSpCas9	negative selection	287590
46008093	46008116	CHR_HSCHR17_2_CTG5	-	26472758	KBM7	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000277956	-1.7321249039226359	[468,418]	[47,75]	-8	hSpCas9	negative selection	287591
46101388	46101411	CHR_HSCHR17_1_CTG5	+	26472758	KBM7	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000276155	-1.7321249039226359	[468,418]	[47,75]	-8	hSpCas9	negative selection	287592
45996505	45996528	17	+	26472758	KBM7	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-1.070115632779835	[498,366]	[68,119]	-7	hSpCas9	negative selection	287593
46008121	46008144	CHR_HSCHR17_2_CTG5	+	26472758	KBM7	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000277956	-1.070115632779835	[498,366]	[68,119]	-7	hSpCas9	negative selection	287594
46010995	46011018	CHR_HSCHR17_2_CTG5	-	26472758	KBM7	viability	TGAATCATCCACTCACACAGAGG	MAPT	ENSG00000277956	-0.3618151152533559	[662,574]	[311,148]	-3	hSpCas9	negative selection	348901
46010964	46010987	CHR_HSCHR17_2_CTG5	-	26472758	KBM7	viability	AATTAACCCCGCATTCAATGAGG	MAPT	ENSG00000277956	-0.004327192020696424	[975,1090]	[534,448]	0	hSpCas9	negative selection	348903
46011071	46011094	CHR_HSCHR17_2_CTG5	-	26472758	KBM7	viability	GCCAACCTCAGATGAACTCAGGG	MAPT	ENSG00000277956	0.21031367204550844	[995,820]	[524,461]	2	hSpCas9	negative selection	348907
46010887	46010910	CHR_HSCHR17_2_CTG5	+	26472758	KBM7	viability	GTCTGGGCCATGAGTGAGGGTGG	MAPT	ENSG00000277956	-0.7034285376693088	[59,115]	[28,23]	-5	hSpCas9	negative selection	348909
46010957	46010980	CHR_HSCHR17_2_CTG5	+	26472758	KBM7	viability	GGCCGGCCCTCATTGAATGCGGG	MAPT	ENSG00000277956	0.32904006713279554	[970,552]	[625,272]	3	hSpCas9	negative selection	348912
46011030	46011053	CHR_HSCHR17_2_CTG5	+	26472758	KBM7	viability	CAGAACCCTCAGCTTAGCATGGG	MAPT	ENSG00000277956	-0.04105707890776822	[1637,1308]	[763,583]	0	hSpCas9	negative selection	348916
46011084	46011107	CHR_HSCHR17_2_CTG5	+	26472758	KBM7	viability	TGAGGTTGGCTTGGAAGGTGTGG	MAPT	ENSG00000277956	0.568458905259412	[625,573]	[398,435]	6	hSpCas9	negative selection	348918
46011189	46011212	CHR_HSCHR17_2_CTG5	-	26472758	KBM7	viability	GACAGTTCTGGCCCTGAAAGGGG	MAPT	ENSG00000277956	-0.5415334046789076	[438,404]	[118,151]	-5	hSpCas9	negative selection	348922
46011211	46011234	CHR_HSCHR17_2_CTG5	-	26472758	KBM7	viability	AGGGCAGCTGCAGGGTGGGAGGG	MAPT	ENSG00000277956	0.17130252702827692	[249,361]	[234,103]	1	hSpCas9	negative selection	348925
46011229	46011252	CHR_HSCHR17_2_CTG5	+	26472758	KBM7	viability	GCCCTGCCTCTGCCCATGAGGGG	MAPT	ENSG00000277956	-0.3040347842818629	[1085,1373]	[658,312]	-3	hSpCas9	negative selection	348928
45962362	45962385	17	+	26472758	Raji	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	1.089005006058745	[78]	[38]	8	hSpCas9	negative selection	478684
45973987	45974010	CHR_HSCHR17_2_CTG5	+	26472758	Raji	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000277956	1.089005006058745	[78]	[38]	8	hSpCas9	negative selection	478685
46135453	46135476	CHR_HSCHR17_1_CTG5	-	26472758	Raji	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000276155	1.089005006058745	[78]	[38]	8	hSpCas9	negative selection	478686
46008247	46008270	CHR_HSCHR17_2_CTG5	+	26472758	Raji	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000277956	-0.43071236030958227	[423]	[72]	-4	hSpCas9	negative selection	478687
45996631	45996654	17	+	26472758	Raji	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	-0.43071236030958227	[423]	[72]	-4	hSpCas9	negative selection	478688
46101234	46101257	CHR_HSCHR17_1_CTG5	-	26472758	Raji	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000276155	-0.43071236030958227	[423]	[72]	-4	hSpCas9	negative selection	478689
45990034	45990057	CHR_HSCHR17_2_CTG5	+	26472758	Raji	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000277956	1.0090814617617956	[166]	[77]	8	hSpCas9	negative selection	478690
45978419	45978442	17	+	26472758	Raji	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	1.0090814617617956	[166]	[77]	8	hSpCas9	negative selection	478691
46119505	46119528	CHR_HSCHR17_1_CTG5	-	26472758	Raji	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000276155	1.0090814617617956	[166]	[77]	8	hSpCas9	negative selection	478692
46135466	46135489	CHR_HSCHR17_1_CTG5	+	26472758	Raji	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000276155	0.4262057193931401	[278]	[86]	4	hSpCas9	negative selection	478693
45962349	45962372	17	-	26472758	Raji	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	0.4262057193931401	[278]	[86]	4	hSpCas9	negative selection	478694
45973974	45973997	CHR_HSCHR17_2_CTG5	-	26472758	Raji	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000277956	0.4262057193931401	[278]	[86]	4	hSpCas9	negative selection	478695
45974065	45974088	CHR_HSCHR17_2_CTG5	+	26472758	Raji	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000277956	-0.2676558959733254	[248]	[47]	-2	hSpCas9	negative selection	478696
45962440	45962463	17	+	26472758	Raji	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	-0.2676558959733254	[248]	[47]	-2	hSpCas9	negative selection	478697
46135375	46135398	CHR_HSCHR17_1_CTG5	-	26472758	Raji	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000276155	-0.2676558959733254	[248]	[47]	-2	hSpCas9	negative selection	478698
46106391	46106414	CHR_HSCHR17_1_CTG5	-	26472758	Raji	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000276155	0.23493358509411064	[237]	[64]	2	hSpCas9	negative selection	478699
45991473	45991496	17	+	26472758	Raji	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.23493358509411064	[237]	[64]	2	hSpCas9	negative selection	478700
46003089	46003112	CHR_HSCHR17_2_CTG5	+	26472758	Raji	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000277956	0.23493358509411064	[237]	[64]	2	hSpCas9	negative selection	478701
46008013	46008036	CHR_HSCHR17_2_CTG5	+	26472758	Raji	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000277956	-0.6158360514237856	[382]	[57]	-5	hSpCas9	negative selection	478702
45996397	45996420	17	+	26472758	Raji	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	-0.6158360514237856	[382]	[57]	-5	hSpCas9	negative selection	478703
46101468	46101491	CHR_HSCHR17_1_CTG5	-	26472758	Raji	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000276155	-0.6158360514237856	[382]	[57]	-5	hSpCas9	negative selection	478704
46008023	46008046	CHR_HSCHR17_2_CTG5	+	26472758	Raji	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000277956	-0.9297057833616205	[196]	[23]	-6	hSpCas9	negative selection	478705
45996407	45996430	17	+	26472758	Raji	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	-0.9297057833616205	[196]	[23]	-6	hSpCas9	negative selection	478706
46101458	46101481	CHR_HSCHR17_1_CTG5	-	26472758	Raji	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000276155	-0.9297057833616205	[196]	[23]	-6	hSpCas9	negative selection	478707
45996477	45996500	17	-	26472758	Raji	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-1.6405175364737623	[308]	[22]	-8	hSpCas9	negative selection	478708
46008093	46008116	CHR_HSCHR17_2_CTG5	-	26472758	Raji	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000277956	-1.6405175364737623	[308]	[22]	-8	hSpCas9	negative selection	478709
46101388	46101411	CHR_HSCHR17_1_CTG5	+	26472758	Raji	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000276155	-1.6405175364737623	[308]	[22]	-8	hSpCas9	negative selection	478710
45996505	45996528	17	+	26472758	Raji	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-2.12965566192725	[263]	[13]	-8	hSpCas9	negative selection	478711
46008121	46008144	CHR_HSCHR17_2_CTG5	+	26472758	Raji	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000277956	-2.12965566192725	[263]	[13]	-8	hSpCas9	negative selection	478712
46010995	46011018	CHR_HSCHR17_2_CTG5	-	26472758	Raji	viability	TGAATCATCCACTCACACAGAGG	MAPT	ENSG00000277956	-0.32285637054891464	[317]	[58]	-3	hSpCas9	negative selection	540019
46010964	46010987	CHR_HSCHR17_2_CTG5	-	26472758	Raji	viability	AATTAACCCCGCATTCAATGAGG	MAPT	ENSG00000277956	0.23073017019558284	[660]	[179]	2	hSpCas9	negative selection	540021
46011071	46011094	CHR_HSCHR17_2_CTG5	-	26472758	Raji	viability	GCCAACCTCAGATGAACTCAGGG	MAPT	ENSG00000277956	0.18050146457761496	[326]	[85]	1	hSpCas9	negative selection	540025
46010887	46010910	CHR_HSCHR17_2_CTG5	+	26472758	Raji	viability	GTCTGGGCCATGAGTGAGGGTGG	MAPT	ENSG00000277956	0.42931163026096186	[15]	[4]	4	hSpCas9	negative selection	540027
46010957	46010980	CHR_HSCHR17_2_CTG5	+	26472758	Raji	viability	GGCCGGCCCTCATTGAATGCGGG	MAPT	ENSG00000277956	0.04363111414226328	[346]	[82]	0	hSpCas9	negative selection	540030
46011030	46011053	CHR_HSCHR17_2_CTG5	+	26472758	Raji	viability	CAGAACCCTCAGCTTAGCATGGG	MAPT	ENSG00000277956	-0.27304020882390745	[603]	[115]	-2	hSpCas9	negative selection	540034
46011084	46011107	CHR_HSCHR17_2_CTG5	+	26472758	Raji	viability	TGAGGTTGGCTTGGAAGGTGTGG	MAPT	ENSG00000277956	-0.2986088243022374	[370]	[69]	-3	hSpCas9	negative selection	540036
46011189	46011212	CHR_HSCHR17_2_CTG5	-	26472758	Raji	viability	GACAGTTCTGGCCCTGAAAGGGG	MAPT	ENSG00000277956	0.15521206046421468	[266]	[68]	1	hSpCas9	negative selection	540040
46011211	46011234	CHR_HSCHR17_2_CTG5	-	26472758	Raji	viability	AGGGCAGCTGCAGGGTGGGAGGG	MAPT	ENSG00000277956	-0.9114754918777161	[153]	[18]	-6	hSpCas9	negative selection	540043
46011229	46011252	CHR_HSCHR17_2_CTG5	+	26472758	Raji	viability	GCCCTGCCTCTGCCCATGAGGGG	MAPT	ENSG00000277956	-0.06815507253223951	[514]	[113]	0	hSpCas9	negative selection	540046
45962362	45962385	17	+	26472758	K562	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	-0.9432082755093243	[163]	[71]	-5	hSpCas9	negative selection	669802
45973987	45974010	CHR_HSCHR17_2_CTG5	+	26472758	K562	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000277956	-0.9432082755093243	[163]	[71]	-5	hSpCas9	negative selection	669803
46135453	46135476	CHR_HSCHR17_1_CTG5	-	26472758	K562	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000276155	-0.9432082755093243	[163]	[71]	-5	hSpCas9	negative selection	669804
46008247	46008270	CHR_HSCHR17_2_CTG5	+	26472758	K562	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000277956	1.0299411420108537	[408]	[704]	8	hSpCas9	negative selection	669805
45996631	45996654	17	+	26472758	K562	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	1.0299411420108537	[408]	[704]	8	hSpCas9	negative selection	669806
46101234	46101257	CHR_HSCHR17_1_CTG5	-	26472758	K562	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000276155	1.0299411420108537	[408]	[704]	8	hSpCas9	negative selection	669807
45990034	45990057	CHR_HSCHR17_2_CTG5	+	26472758	K562	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000277956	0.5595416446486949	[339]	[422]	4	hSpCas9	negative selection	669808
45978419	45978442	17	+	26472758	K562	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.5595416446486949	[339]	[422]	4	hSpCas9	negative selection	669809
46119505	46119528	CHR_HSCHR17_1_CTG5	-	26472758	K562	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000276155	0.5595416446486949	[339]	[422]	4	hSpCas9	negative selection	669810
46135466	46135489	CHR_HSCHR17_1_CTG5	+	26472758	K562	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000276155	-0.2662822356473217	[690]	[484]	-2	hSpCas9	negative selection	669811
45962349	45962372	17	-	26472758	K562	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	-0.2662822356473217	[690]	[484]	-2	hSpCas9	negative selection	669812
45973974	45973997	CHR_HSCHR17_2_CTG5	-	26472758	K562	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000277956	-0.2662822356473217	[690]	[484]	-2	hSpCas9	negative selection	669813
45974065	45974088	CHR_HSCHR17_2_CTG5	+	26472758	K562	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000277956	1.0193521720316736	[449]	[769]	8	hSpCas9	negative selection	669814
45962440	45962463	17	+	26472758	K562	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	1.0193521720316736	[449]	[769]	8	hSpCas9	negative selection	669815
46135375	46135398	CHR_HSCHR17_1_CTG5	-	26472758	K562	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000276155	1.0193521720316736	[449]	[769]	8	hSpCas9	negative selection	669816
46106391	46106414	CHR_HSCHR17_1_CTG5	-	26472758	K562	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000276155	1.15734227084217	[349]	[658]	8	hSpCas9	negative selection	669817
45991473	45991496	17	+	26472758	K562	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	1.15734227084217	[349]	[658]	8	hSpCas9	negative selection	669818
46003089	46003112	CHR_HSCHR17_2_CTG5	+	26472758	K562	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000277956	1.15734227084217	[349]	[658]	8	hSpCas9	negative selection	669819
46008013	46008036	CHR_HSCHR17_2_CTG5	+	26472758	K562	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000277956	0.6995578854136181	[611]	[838]	6	hSpCas9	negative selection	669820
45996397	45996420	17	+	26472758	K562	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	0.6995578854136181	[611]	[838]	6	hSpCas9	negative selection	669821
46101468	46101491	CHR_HSCHR17_1_CTG5	-	26472758	K562	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000276155	0.6995578854136181	[611]	[838]	6	hSpCas9	negative selection	669822
46008023	46008046	CHR_HSCHR17_2_CTG5	+	26472758	K562	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000277956	-0.11313327695163677	[245]	[191]	-1	hSpCas9	negative selection	669823
45996407	45996430	17	+	26472758	K562	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	-0.11313327695163677	[245]	[191]	-1	hSpCas9	negative selection	669824
46101458	46101481	CHR_HSCHR17_1_CTG5	-	26472758	K562	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000276155	-0.11313327695163677	[245]	[191]	-1	hSpCas9	negative selection	669825
45996477	45996500	17	-	26472758	K562	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-6.571498207894582	[337]	[2]	-9	hSpCas9	negative selection	669826
46008093	46008116	CHR_HSCHR17_2_CTG5	-	26472758	K562	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000277956	-6.571498207894582	[337]	[2]	-9	hSpCas9	negative selection	669827
46101388	46101411	CHR_HSCHR17_1_CTG5	+	26472758	K562	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000276155	-6.571498207894582	[337]	[2]	-9	hSpCas9	negative selection	669828
45996505	45996528	17	+	26472758	K562	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-1.8197116097532688	[367]	[87]	-7	hSpCas9	negative selection	669829
46008121	46008144	CHR_HSCHR17_2_CTG5	+	26472758	K562	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000277956	-1.8197116097532688	[367]	[87]	-7	hSpCas9	negative selection	669830
46010995	46011018	CHR_HSCHR17_2_CTG5	-	26472758	K562	viability	TGAATCATCCACTCACACAGAGG	MAPT	ENSG00000277956	0.02567870078933221	[525]	[451]	0	hSpCas9	negative selection	731137
46010964	46010987	CHR_HSCHR17_2_CTG5	-	26472758	K562	viability	AATTAACCCCGCATTCAATGAGG	MAPT	ENSG00000277956	0.36954611512010205	[893]	[974]	3	hSpCas9	negative selection	731139
46011071	46011094	CHR_HSCHR17_2_CTG5	-	26472758	K562	viability	GCCAACCTCAGATGAACTCAGGG	MAPT	ENSG00000277956	-0.09054764200901322	[916]	[726]	0	hSpCas9	negative selection	731143
46010887	46010910	CHR_HSCHR17_2_CTG5	+	26472758	K562	viability	GTCTGGGCCATGAGTGAGGGTGG	MAPT	ENSG00000277956	1.4668111490028948	[44]	[104]	9	hSpCas9	negative selection	731145
46010957	46010980	CHR_HSCHR17_2_CTG5	+	26472758	K562	viability	GGCCGGCCCTCATTGAATGCGGG	MAPT	ENSG00000277956	0.9127473586156896	[649]	[1032]	7	hSpCas9	negative selection	731148
46011030	46011053	CHR_HSCHR17_2_CTG5	+	26472758	K562	viability	CAGAACCCTCAGCTTAGCATGGG	MAPT	ENSG00000277956	0.27218799348004685	[1131]	[1153]	2	hSpCas9	negative selection	731152
46011084	46011107	CHR_HSCHR17_2_CTG5	+	26472758	K562	viability	TGAGGTTGGCTTGGAAGGTGTGG	MAPT	ENSG00000277956	-0.34160030553758514	[682]	[454]	-2	hSpCas9	negative selection	731154
46011189	46011212	CHR_HSCHR17_2_CTG5	-	26472758	K562	viability	GACAGTTCTGGCCCTGAAAGGGG	MAPT	ENSG00000277956	0.3851973834492428	[399]	[440]	3	hSpCas9	negative selection	731158
46011211	46011234	CHR_HSCHR17_2_CTG5	-	26472758	K562	viability	AGGGCAGCTGCAGGGTGGGAGGG	MAPT	ENSG00000277956	-0.5562724641101464	[269]	[154]	-3	hSpCas9	negative selection	731161
46011229	46011252	CHR_HSCHR17_2_CTG5	+	26472758	K562	viability	GCCCTGCCTCTGCCCATGAGGGG	MAPT	ENSG00000277956	-1.6066186332085544	[1139]	[315]	-7	hSpCas9	negative selection	731164
45971882	45971905	17	+	26627737	DLD1	viability	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	0.4190256208380898	[125]	[27,36,86]	4	hSpCas9	negative selection	798290
45972062	45972085	17	+	26627737	DLD1	viability	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	-0.14326408683217523	[472]	[123,195,90]	-1	hSpCas9	negative selection	798291
45978371	45978394	17	-	26627737	DLD1	viability	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	1.6333957346203336	[244]	[262,253,201]	9	hSpCas9	negative selection	798292
45983569	45983592	17	+	26627737	DLD1	viability	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-2.0207594577879386	[1577]	[206,33,119]	-8	hSpCas9	negative selection	798293
45990039	45990062	17	+	26627737	DLD1	viability	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.12157393425904531	[552]	[193,150,134]	-1	hSpCas9	negative selection	798294
45991522	45991545	17	-	26627737	DLD1	viability	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	1.1823623327584645	[86]	[94,34,54]	9	hSpCas9	negative selection	798295
45971882	45971905	17	+	26627737	GBM cells	viability after 5 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	0.004847319634750713	[104]	[67,44]	0	hSpCas9	negative selection	880605
45972062	45972085	17	+	26627737	GBM cells	viability after 5 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	0.4507095116716424	[175]	[138,118]	6	hSpCas9	negative selection	880606
45978371	45978394	17	-	26627737	GBM cells	viability after 5 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	0.29155685222768873	[210]	[144,131]	4	hSpCas9	negative selection	880607
45983569	45983592	17	+	26627737	GBM cells	viability after 5 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-0.6951364986634297	[636]	[239,181]	-8	hSpCas9	negative selection	880608
45990039	45990062	17	+	26627737	GBM cells	viability after 5 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	0.2520607003837682	[255]	[165,160]	4	hSpCas9	negative selection	880609
45991522	45991545	17	-	26627737	GBM cells	viability after 5 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	1.4525122046975067	[61]	[100,80]	9	hSpCas9	negative selection	880610
45971882	45971905	17	+	26627737	GBM cells	viability after 13 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-0.509949122278164	[104]	[55,26]	-6	hSpCas9	negative selection	962920
45972062	45972085	17	+	26627737	GBM cells	viability after 13 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	0.4324178072411455	[175]	[140,118]	5	hSpCas9	negative selection	962921
45978371	45978394	17	-	26627737	GBM cells	viability after 13 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	-0.2740620449013991	[210]	[140,56]	-3	hSpCas9	negative selection	962922
45983569	45983592	17	+	26627737	GBM cells	viability after 13 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-0.5084085637766232	[636]	[253,233]	-6	hSpCas9	negative selection	962923
45990039	45990062	17	+	26627737	GBM cells	viability after 13 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.5601516348972084	[255]	[91,95]	-6	hSpCas9	negative selection	962924
45991522	45991545	17	-	26627737	GBM cells	viability after 13 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	1.9809542443094534	[61]	[134,130]	9	hSpCas9	negative selection	962925
45971882	45971905	17	+	26627737	GBM cells	viability after 21 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-5.834012218050464	[104]	[0,0]	-9	hSpCas9	negative selection	1045235
45972062	45972085	17	+	26627737	GBM cells	viability after 21 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	-0.05093957626322715	[175]	[96,87]	0	hSpCas9	negative selection	1045236
45978371	45978394	17	-	26627737	GBM cells	viability after 21 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	0.22103028812356534	[210]	[130,135]	2	hSpCas9	negative selection	1045237
45983569	45983592	17	+	26627737	GBM cells	viability after 21 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-1.187938203025921	[636]	[165,138]	-7	hSpCas9	negative selection	1045238
45990039	45990062	17	+	26627737	GBM cells	viability after 21 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.14503345899477157	[255]	[130,120]	-1	hSpCas9	negative selection	1045239
45991522	45991545	17	-	26627737	GBM cells	viability after 21 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	1.616267822409833	[61]	[96,108]	9	hSpCas9	negative selection	1045240
45971882	45971905	17	+	26627737	RPE1	viability after 9 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-0.5113264461733298	[147]	[35,27]	-4	hSpCas9	negative selection	1127550
45972062	45972085	17	+	26627737	RPE1	viability after 9 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	1.5334275254423917	[447]	[374,445]	8	hSpCas9	negative selection	1127551
45978371	45978394	17	-	26627737	RPE1	viability after 9 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	1.6249452890037963	[528]	[660,316]	8	hSpCas9	negative selection	1127552
45983569	45983592	17	+	26627737	RPE1	viability after 9 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	0.10987488677723392	[763]	[96,465]	0	hSpCas9	negative selection	1127553
45990039	45990062	17	+	26627737	RPE1	viability after 9 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-1.7055459547086405	[1368]	[209,29]	-8	hSpCas9	negative selection	1127554
45991522	45991545	17	-	26627737	RPE1	viability after 9 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	1.3519545382110212	[129]	[109,95]	7	hSpCas9	negative selection	1127555
45971882	45971905	17	+	26627737	RPE1	viability after 12 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-2.6482091045506726	[147]	[0,11]	-9	hSpCas9	negative selection	1209865
45972062	45972085	17	+	26627737	RPE1	viability after 12 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	1.4390011419269146	[447]	[337,313]	7	hSpCas9	negative selection	1209866
45978371	45978394	17	-	26627737	RPE1	viability after 12 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	1.3367127102661103	[528]	[408,305]	7	hSpCas9	negative selection	1209867
45983569	45983592	17	+	26627737	RPE1	viability after 12 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-0.4352894358345069	[763]	[110,194]	-3	hSpCas9	negative selection	1209868
45990039	45990062	17	+	26627737	RPE1	viability after 12 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-1.2109497147250308	[1368]	[256,54]	-7	hSpCas9	negative selection	1209869
45991522	45991545	17	-	26627737	RPE1	viability after 12 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	0.4993480838631852	[129]	[44,53]	3	hSpCas9	negative selection	1209870
45971882	45971905	17	+	26627737	RPE1	viability after 15 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-0.6222177464268683	[147]	[15,37]	-4	hSpCas9	negative selection	1292180
45972062	45972085	17	+	26627737	RPE1	viability after 15 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	1.8416540203671456	[447]	[525,384]	8	hSpCas9	negative selection	1292181
45978371	45978394	17	-	26627737	RPE1	viability after 15 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	1.2390736892476624	[528]	[452,256]	7	hSpCas9	negative selection	1292182
45983569	45983592	17	+	26627737	RPE1	viability after 15 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-0.38832944690166915	[763]	[45,279]	-2	hSpCas9	negative selection	1292183
45990039	45990062	17	+	26627737	RPE1	viability after 15 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-1.6518596842446365	[1368]	[137,108]	-7	hSpCas9	negative selection	1292184
45991522	45991545	17	-	26627737	RPE1	viability after 15 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	0.8314080826906423	[129]	[68,61]	5	hSpCas9	negative selection	1292185
45971882	45971905	17	+	26627737	RPE1	viability after 18 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-1.601053410254	[147]	[17,7]	-7	hSpCas9	negative selection	1374495
45972062	45972085	17	+	26627737	RPE1	viability after 18 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	1.7415399215996863	[447]	[499,301]	8	hSpCas9	negative selection	1374496
45978371	45978394	17	-	26627737	RPE1	viability after 18 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	1.6160507749507524	[528]	[673,184]	8	hSpCas9	negative selection	1374497
45983569	45983592	17	+	26627737	RPE1	viability after 18 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-0.5138052258939235	[763]	[24,271]	-3	hSpCas9	negative selection	1374498
45990039	45990062	17	+	26627737	RPE1	viability after 18 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-1.7638796984700686	[1368]	[189,21]	-8	hSpCas9	negative selection	1374499
45991522	45991545	17	-	26627737	RPE1	viability after 18 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	0.8810167062118128	[129]	[96,29]	5	hSpCas9	negative selection	1374500
45971882	45971905	17	+	26627737	HeLa	viability after 8 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	0.4362189064332648	[148]	[37,211,7]	4	hSpCas9	negative selection	1456810
45972062	45972085	17	+	26627737	HeLa	viability after 8 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	-1.6060506127138792	[484]	[127,39,53]	-9	hSpCas9	negative selection	1456811
45978371	45978394	17	-	26627737	HeLa	viability after 8 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	0.2924600337838668	[304]	[187,168,137]	2	hSpCas9	negative selection	1456812
45983569	45983592	17	+	26627737	HeLa	viability after 8 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-0.6975585344304318	[901]	[405,200,160]	-6	hSpCas9	negative selection	1456813
45990039	45990062	17	+	26627737	HeLa	viability after 8 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	0.14274179022413494	[400]	[331,104,172]	1	hSpCas9	negative selection	1456814
45991522	45991545	17	-	26627737	HeLa	viability after 8 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	-0.7479525863550998	[231]	[61,91,28]	-6	hSpCas9	negative selection	1456815
45971882	45971905	17	+	26627737	HeLa	viability after 12 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-1.70459481335632	[148]	[8,31,13]	-9	hSpCas9	negative selection	1539125
45972062	45972085	17	+	26627737	HeLa	viability after 12 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	-0.009029840751839102	[484]	[367,127,113]	0	hSpCas9	negative selection	1539126
45978371	45978394	17	-	26627737	HeLa	viability after 12 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	0.26190731905659587	[304]	[143,237,61]	2	hSpCas9	negative selection	1539127
45983569	45983592	17	+	26627737	HeLa	viability after 12 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-0.5623639437051683	[901]	[401,116,256]	-5	hSpCas9	negative selection	1539128
45990039	45990062	17	+	26627737	HeLa	viability after 12 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.31584435244626996	[400]	[165,145,86]	-3	hSpCas9	negative selection	1539129
45991522	45991545	17	-	26627737	HeLa	viability after 12 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	0.22208808069719732	[231]	[104,142,83]	2	hSpCas9	negative selection	1539130
45971882	45971905	17	+	26627737	HeLa	viability after 15 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-1.187942857847075	[148]	[19,56,0]	-8	hSpCas9	negative selection	1621440
45972062	45972085	17	+	26627737	HeLa	viability after 15 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	-0.1470019345616209	[484]	[118,77,351]	-1	hSpCas9	negative selection	1621441
45978371	45978394	17	-	26627737	HeLa	viability after 15 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	0.8619586518463807	[304]	[219,304,145]	6	hSpCas9	negative selection	1621442
45983569	45983592	17	+	26627737	HeLa	viability after 15 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-0.5146935630616113	[901]	[198,216,363]	-4	hSpCas9	negative selection	1621443
45990039	45990062	17	+	26627737	HeLa	viability after 15 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.008821773215241954	[400]	[282,138,54]	0	hSpCas9	negative selection	1621444
45991522	45991545	17	-	26627737	HeLa	viability after 15 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	0.134026107914462	[231]	[8,152,153]	1	hSpCas9	negative selection	1621445
45971882	45971905	17	+	26627737	HeLa	viability after 18 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-1.2383233123665611	[148]	[14,42,0]	-8	hSpCas9	negative selection	1703755
45972062	45972085	17	+	26627737	HeLa	viability after 18 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	-0.11782553630084769	[484]	[84,66,351]	-1	hSpCas9	negative selection	1703756
45978371	45978394	17	-	26627737	HeLa	viability after 18 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	0.8339127332932224	[304]	[149,238,145]	6	hSpCas9	negative selection	1703757
45983569	45983592	17	+	26627737	HeLa	viability after 18 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-0.5016740289058097	[901]	[132,185,363]	-4	hSpCas9	negative selection	1703758
45990039	45990062	17	+	26627737	HeLa	viability after 18 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.019651672398880493	[400]	[189,111,54]	0	hSpCas9	negative selection	1703759
45991522	45991545	17	-	26627737	HeLa	viability after 18 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	0.16665143831907647	[231]	[7,129,153]	1	hSpCas9	negative selection	1703760
45971882	45971905	17	+	26627737	HCT116	viability after 6 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-0.291283691548863	[206]	[72,0]	-2	hSpCas9	negative selection	1786070
45972062	45972085	17	+	26627737	HCT116	viability after 6 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	1.9958387296603632	[388]	[114,314]	8	hSpCas9	negative selection	1786071
45978371	45978394	17	-	26627737	HCT116	viability after 6 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	-0.8168449122826456	[860]	[110,57]	-5	hSpCas9	negative selection	1786072
45983569	45983592	17	+	26627737	HCT116	viability after 6 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	0.8969666767199959	[1158]	[609,189]	5	hSpCas9	negative selection	1786073
45990039	45990062	17	+	26627737	HCT116	viability after 6 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-1.3753570327358093	[765]	[77,28]	-7	hSpCas9	negative selection	1786074
45991522	45991545	17	-	26627737	HCT116	viability after 6 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	2.580977533607556	[60]	[48,61]	9	hSpCas9	negative selection	1786075
45971882	45971905	17	+	26627737	HCT116	viability after 8 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	2.9643070009062935	[14]	[81,60,50]	9	hSpCas9	negative selection	1868385
45972062	45972085	17	+	26627737	HCT116	viability after 8 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	-0.048927777768562275	[255]	[137,125,144]	0	hSpCas9	negative selection	1868386
45978371	45978394	17	-	26627737	HCT116	viability after 8 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	-0.042201998714563455	[360]	[189,154,233]	0	hSpCas9	negative selection	1868387
45983569	45983592	17	+	26627737	HCT116	viability after 8 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-0.6787857493307955	[705]	[206,243,276]	-7	hSpCas9	negative selection	1868388
45990039	45990062	17	+	26627737	HCT116	viability after 8 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.1744163994029189	[292]	[120,180,126]	-2	hSpCas9	negative selection	1868389
45991522	45991545	17	-	26627737	HCT116	viability after 8 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	0.9974766319629298	[74]	[111,48,86]	8	hSpCas9	negative selection	1868390
45971882	45971905	17	+	26627737	HCT116	viability after 9 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-2.088057428004765	[206]	[12,12]	-8	hSpCas9	negative selection	1950700
45972062	45972085	17	+	26627737	HCT116	viability after 9 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	0.23709927319048324	[388]	[146,102]	1	hSpCas9	negative selection	1950701
45978371	45978394	17	-	26627737	HCT116	viability after 9 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	-0.7271546260977603	[860]	[201,88]	-5	hSpCas9	negative selection	1950702
45983569	45983592	17	+	26627737	HCT116	viability after 9 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-0.00015242956704553112	[1158]	[309,308]	0	hSpCas9	negative selection	1950703
45990039	45990062	17	+	26627737	HCT116	viability after 9 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.7707288982154383	[765]	[120,118]	-5	hSpCas9	negative selection	1950704
45991522	45991545	17	-	26627737	HCT116	viability after 9 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	2.5537892628106693	[60]	[203,9]	9	hSpCas9	negative selection	1950705
45971882	45971905	17	+	26627737	HCT116	viability after 12 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	3.182363721554994	[14]	[30,143,44]	9	hSpCas9	negative selection	2033015
45972062	45972085	17	+	26627737	HCT116	viability after 12 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	0.18831307792041707	[255]	[136,57,263]	2	hSpCas9	negative selection	2033016
45978371	45978394	17	-	26627737	HCT116	viability after 12 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	-0.22209534028782035	[360]	[128,166,194]	-2	hSpCas9	negative selection	2033017
45983569	45983592	17	+	26627737	HCT116	viability after 12 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-1.1810404957336982	[705]	[101,191,202]	-8	hSpCas9	negative selection	2033018
45990039	45990062	17	+	26627737	HCT116	viability after 12 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.6867971782896807	[292]	[98,108,78]	-6	hSpCas9	negative selection	2033019
45991522	45991545	17	-	26627737	HCT116	viability after 12 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	1.116807209424259	[74]	[82,99,73]	8	hSpCas9	negative selection	2033020
45971882	45971905	17	+	26627737	HCT116	viability after 15 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	2.5514006386664345	[14]	[98,57,0]	9	hSpCas9	negative selection	2115330
45972062	45972085	17	+	26627737	HCT116	viability after 15 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	0.4931344028638296	[255]	[223,119,277]	4	hSpCas9	negative selection	2115331
45978371	45978394	17	-	26627737	HCT116	viability after 15 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	0.3265074100600874	[360]	[161,179,423]	3	hSpCas9	negative selection	2115332
45983569	45983592	17	+	26627737	HCT116	viability after 15 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-1.1297569573663815	[705]	[109,192,242]	-8	hSpCas9	negative selection	2115333
45990039	45990062	17	+	26627737	HCT116	viability after 15 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.24988610797020458	[292]	[200,108,121]	-3	hSpCas9	negative selection	2115334
45991522	45991545	17	-	26627737	HCT116	viability after 15 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	0.6753385165067023	[74]	[69,108,27]	6	hSpCas9	negative selection	2115335
45971882	45971905	17	+	26627737	HCT116	viability after 18 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	3.12588995606556	[14]	[9,92,85]	9	hSpCas9	negative selection	2197645
45972062	45972085	17	+	26627737	HCT116	viability after 18 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	0.5360475825109385	[255]	[115,182,241]	4	hSpCas9	negative selection	2197646
45978371	45978394	17	-	26627737	HCT116	viability after 18 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	0.2578791130122758	[360]	[286,176,161]	2	hSpCas9	negative selection	2197647
45983569	45983592	17	+	26627737	HCT116	viability after 18 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-0.9791720228747425	[705]	[142,171,205]	-7	hSpCas9	negative selection	2197648
45990039	45990062	17	+	26627737	HCT116	viability after 18 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.29367434072968424	[292]	[98,93,156]	-3	hSpCas9	negative selection	2197649
45991522	45991545	17	-	26627737	HCT116	viability after 18 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	0.16599396400148358	[74]	[46,46,26]	1	hSpCas9	negative selection	2197650
45962348	45962371	17	-	24336569	HL60	viability	CATCACTTCGAACTCCTGGCGGG	MAPT	ENSG00000186868	2.2924747928350095	[78]	[818]	9	hSpCas9	negative selection	2276258
45962362	45962385	17	+	24336569	HL60	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	-0.1405185266934817	[560]	[1076]	-1	hSpCas9	negative selection	2276259
45962371	45962394	17	+	24336569	HL60	viability	GAAGATCACGCTGGGACGTACGG	MAPT	ENSG00000186868	0.6975979770164042	[536]	[1842]	6	hSpCas9	negative selection	2276260
45962376	45962399	17	+	24336569	HL60	viability	TCACGCTGGGACGTACGGGTTGG	MAPT	ENSG00000186868	-0.09309880111229962	[248]	[493]	-1	hSpCas9	negative selection	2276261
45962424	45962447	17	+	24336569	HL60	viability	CACCATGCACCAAGACCAAGAGG	MAPT	ENSG00000186868	0.6452723612204234	[551]	[1826]	5	hSpCas9	negative selection	2276262
45962433	45962456	17	-	24336569	HL60	viability	CCGTGTCACCCTCTTGGTCTTGG	MAPT	ENSG00000186868	0.1924586213476338	[219]	[531]	1	hSpCas9	negative selection	2276263
45962439	45962462	17	-	24336569	HL60	viability	CAGCGTCCGTGTCACCCTCTTGG	MAPT	ENSG00000186868	0.002600164159578172	[524]	[1112]	0	hSpCas9	negative selection	2276264
45962449	45962472	17	+	24336569	HL60	viability	GACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.47205535244137875	[602]	[1769]	4	hSpCas9	negative selection	2276265
45962463	45962486	17	-	24336569	HL60	viability	TGGCTGTCCACTAACCTTTCAGG	MAPT	ENSG00000186868	-0.6260123329041446	[263]	[361]	-5	hSpCas9	negative selection	2276266
45978365	45978388	17	+	24336569	HL60	viability	CATACACCAGCTGAAGAAGCAGG	MAPT	ENSG00000186868	0.5273451420466275	[239]	[731]	5	hSpCas9	negative selection	2276267
45962348	45962371	17	-	24336569	KBM7	viability	CATCACTTCGAACTCCTGGCGGG	MAPT	ENSG00000186868	-0.46065902359287236	[276]	[548]	-4	hSpCas9	negative selection	2343435
45962362	45962385	17	+	24336569	KBM7	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	-0.7420577717063935	[435]	[710]	-5	hSpCas9	negative selection	2343436
45962371	45962394	17	+	24336569	KBM7	viability	GAAGATCACGCTGGGACGTACGG	MAPT	ENSG00000186868	-0.9602161905396172	[850]	[1192]	-6	hSpCas9	negative selection	2343437
45962376	45962399	17	+	24336569	KBM7	viability	TCACGCTGGGACGTACGGGTTGG	MAPT	ENSG00000186868	-0.24485078535802843	[400]	[922]	-2	hSpCas9	negative selection	2343438
45962424	45962447	17	+	24336569	KBM7	viability	CACCATGCACCAAGACCAAGAGG	MAPT	ENSG00000186868	0.3363536105074805	[549]	[1893]	3	hSpCas9	negative selection	2343439
45962433	45962456	17	-	24336569	KBM7	viability	CCGTGTCACCCTCTTGGTCTTGG	MAPT	ENSG00000186868	1.7331363940223514	[73]	[670]	9	hSpCas9	negative selection	2343440
45962439	45962462	17	-	24336569	KBM7	viability	CAGCGTCCGTGTCACCCTCTTGG	MAPT	ENSG00000186868	0.515209724354045	[323]	[1262]	5	hSpCas9	negative selection	2343441
45962449	45962472	17	+	24336569	KBM7	viability	GACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.8238464795440519	[499]	[2413]	7	hSpCas9	negative selection	2343442
45962463	45962486	17	-	24336569	KBM7	viability	TGGCTGTCCACTAACCTTTCAGG	MAPT	ENSG00000186868	1.2696501795560615	[91]	[604]	9	hSpCas9	negative selection	2343443
45978365	45978388	17	+	24336569	KBM7	viability	CATACACCAGCTGAAGAAGCAGG	MAPT	ENSG00000186868	-0.14913945458389	[160]	[395]	-1	hSpCas9	negative selection	2343444
46098758	46098781	CHR_HSCHR17_1_CTG5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CATTCCCCACCATGGGACACAGG	MAPT	ENSG00000276155	-1.0953980847134903	[89,32]	[9,1]	-6	dCas9-VP64	positive selection	2388114
46010723	46010746	CHR_HSCHR17_2_CTG5	-	25494202	A375	resistance to PLX-4720 (puromycin)	CATTCCCCACCATGGGACACAGG	MAPT	ENSG00000277956	-1.0953980847134903	[89,32]	[9,1]	-6	dCas9-VP64	positive selection	2388115
45999107	45999130	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CATTCCCCACCATGGGACACAGG	MAPT	ENSG00000186868	-1.0953980847134903	[89,32]	[9,1]	-6	dCas9-VP64	positive selection	2388116
46098709	46098732	CHR_HSCHR17_1_CTG5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAACTGAACTTGGATTTAAGG	MAPT	ENSG00000276155	-1.58226253192668	[289,149]	[10,20]	-8	dCas9-VP64	positive selection	2388117
46010772	46010795	CHR_HSCHR17_2_CTG5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAACTGAACTTGGATTTAAGG	MAPT	ENSG00000277956	-1.58226253192668	[289,149]	[10,20]	-8	dCas9-VP64	positive selection	2388118
45999156	45999179	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAACTGAACTTGGATTTAAGG	MAPT	ENSG00000186868	-1.58226253192668	[289,149]	[10,20]	-8	dCas9-VP64	positive selection	2388119
45999085	45999108	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAGGGTATGGCAGAACCCAGG	MAPT	ENSG00000186868	2.2780381393420313	[52,28]	[76,6]	7	dCas9-VP64	positive selection	2388120
46010701	46010724	CHR_HSCHR17_2_CTG5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAGGGTATGGCAGAACCCAGG	MAPT	ENSG00000277956	2.2780381393420313	[52,28]	[76,6]	7	dCas9-VP64	positive selection	2388121
45950711	45950734	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTTCAGTGGCATGATCTAGG	MAPT	ENSG00000186868	1.2297289136301017	[14,21]	[11,6]	5	dCas9-VP64	positive selection	2407556
45962361	45962384	CHR_HSCHR17_2_CTG5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTTCAGTGGCATGATCTAGG	MAPT	ENSG00000277956	1.2297289136301017	[14,21]	[11,6]	5	dCas9-VP64	positive selection	2407559
46147073	46147096	CHR_HSCHR17_1_CTG5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTTCAGTGGCATGATCTAGG	MAPT	ENSG00000276155	1.2297289136301017	[14,21]	[11,6]	5	dCas9-VP64	positive selection	2407560
46105059	46105082	CHR_HSCHR17_1_CTG5	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACTTGAACCCAGGAGGCAGAGG	MAPT	ENSG00000276155	-1.4184778160092897	[54,284]	[10,16]	-7	dCas9-VP64	positive selection	2414570
45938567	45938590	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	TATTCACAGGTTCTGGGGATTAG	MAPT	ENSG00000186868	-1.6123727665609728	[211,22]	[8,6]	-8	dCas9-VP64	positive selection	2418202
45950201	45950224	CHR_HSCHR17_2_CTG5	+	25494202	A375	resistance to PLX-4720 (puromycin)	TATTCACAGGTTCTGGGGATTAG	MAPT	ENSG00000277956	-1.6123727665609728	[211,22]	[8,6]	-8	dCas9-VP64	positive selection	2418203
46143003	46143026	CHR_HSCHR17_1_CTG5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCGTGTTAGCCAAG	MAPT	ENSG00000276155	0.853016361217498	[78,47]	[31,16]	3	dCas9-VP64	positive selection	2418311
46074534	46074557	CHR_HSCHR17_1_CTG5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACTGCGCCTGG	MAPT	ENSG00000276155	-0.04533809600197003	[16,0]	[1,0]	0	dCas9-VP64	positive selection	2431254
45906699	45906722	CHR_HSCHR17_2_CTG5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGTGTGTGTGTGTGTGGAGG	MAPT	ENSG00000277956	1.250295307438589	[24,5]	[12,2]	5	dCas9-VP64	positive selection	2434551
45895073	45895096	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGTGTGTGTGTGTGTGGAGG	MAPT	ENSG00000186868	1.250295307438589	[24,5]	[12,2]	5	dCas9-VP64	positive selection	2434553
46178100	46178123	CHR_HSCHR17_1_CTG5	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTTTGGGAGGCCAAGGCAGAGG	MAPT	ENSG00000276155	2.0119762381202047	[93,200]	[9,263]	7	dCas9-VP64	positive selection	2462465
46026363	46026386	CHR_HSCHR17_2_CTG5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAGTCCCAGCTACTCCGG	MAPT	ENSG00000277956	0.4848717924049799	[259,492]	[140,88]	2	dCas9-VP64	positive selection	2468736
46014747	46014770	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAGTCCCAGCTACTCCGG	MAPT	ENSG00000186868	0.4848717924049799	[259,492]	[140,88]	2	dCas9-VP64	positive selection	2468737
45939564	45939587	CHR_HSCHR17_2_CTG5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGTTGCAGTGAGCCGAGATGG	MAPT	ENSG00000277956	0.6330757747468561	[50,16]	[8,13]	2	dCas9-VP64	positive selection	2476972
45927933	45927956	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGTTGCAGTGAGCCGAGATGG	MAPT	ENSG00000186868	0.6330757747468561	[50,16]	[8,13]	2	dCas9-VP64	positive selection	2476973
46098758	46098781	CHR_HSCHR17_1_CTG5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CATTCCCCACCATGGGACACAGG	MAPT	ENSG00000276155	0.10367128106766987	[200,319]	[138,45]	0	dCas9-VP64	positive selection	2483369
46010723	46010746	CHR_HSCHR17_2_CTG5	-	25494202	A375	resistance to PLX-4720 (zeocin)	CATTCCCCACCATGGGACACAGG	MAPT	ENSG00000277956	0.10367128106766987	[200,319]	[138,45]	0	dCas9-VP64	positive selection	2483370
45999107	45999130	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CATTCCCCACCATGGGACACAGG	MAPT	ENSG00000186868	0.10367128106766987	[200,319]	[138,45]	0	dCas9-VP64	positive selection	2483371
46098709	46098732	CHR_HSCHR17_1_CTG5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAACTGAACTTGGATTTAAGG	MAPT	ENSG00000276155	-0.5280670049118259	[639,103]	[141,31]	-5	dCas9-VP64	positive selection	2483372
46010772	46010795	CHR_HSCHR17_2_CTG5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAACTGAACTTGGATTTAAGG	MAPT	ENSG00000277956	-0.5280670049118259	[639,103]	[141,31]	-5	dCas9-VP64	positive selection	2483373
45999156	45999179	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAACTGAACTTGGATTTAAGG	MAPT	ENSG00000186868	-0.5280670049118259	[639,103]	[141,31]	-5	dCas9-VP64	positive selection	2483374
45999085	45999108	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAGGGTATGGCAGAACCCAGG	MAPT	ENSG00000186868	-0.13152461760430367	[348,114]	[74,64]	-1	dCas9-VP64	positive selection	2483375
46010701	46010724	CHR_HSCHR17_2_CTG5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAGGGTATGGCAGAACCCAGG	MAPT	ENSG00000277956	-0.13152461760430367	[348,114]	[74,64]	-1	dCas9-VP64	positive selection	2483376
45950711	45950734	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTTCAGTGGCATGATCTAGG	MAPT	ENSG00000186868	3.145747458543453	[46,57]	[48,249]	9	dCas9-VP64	positive selection	2502811
45962361	45962384	CHR_HSCHR17_2_CTG5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTTCAGTGGCATGATCTAGG	MAPT	ENSG00000277956	3.145747458543453	[46,57]	[48,249]	9	dCas9-VP64	positive selection	2502814
46147073	46147096	CHR_HSCHR17_1_CTG5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTTCAGTGGCATGATCTAGG	MAPT	ENSG00000276155	3.145747458543453	[46,57]	[48,249]	9	dCas9-VP64	positive selection	2502815
46105059	46105082	CHR_HSCHR17_1_CTG5	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACTTGAACCCAGGAGGCAGAGG	MAPT	ENSG00000276155	0.5761613238144463	[143,285]	[83,121]	4	dCas9-VP64	positive selection	2509825
45938567	45938590	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	TATTCACAGGTTCTGGGGATTAG	MAPT	ENSG00000186868	-0.08120075685248235	[80,101]	[38,16]	0	dCas9-VP64	positive selection	2513457
45950201	45950224	CHR_HSCHR17_2_CTG5	+	25494202	A375	resistance to PLX-4720 (zeocin)	TATTCACAGGTTCTGGGGATTAG	MAPT	ENSG00000277956	-0.08120075685248235	[80,101]	[38,16]	0	dCas9-VP64	positive selection	2513458
46143003	46143026	CHR_HSCHR17_1_CTG5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCGTGTTAGCCAAG	MAPT	ENSG00000276155	1.9224239682243596	[76,41]	[141,10]	8	dCas9-VP64	positive selection	2513566
46074534	46074557	CHR_HSCHR17_1_CTG5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACTGCGCCTGG	MAPT	ENSG00000276155	-1.0099528387584376	[28,142]	[9,15]	-8	dCas9-VP64	positive selection	2526509
45906699	45906722	CHR_HSCHR17_2_CTG5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGTGTGTGTGTGTGTGGAGG	MAPT	ENSG00000277956	0.8668431868856517	[26,20]	[22,6]	6	dCas9-VP64	positive selection	2529806
45895073	45895096	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGTGTGTGTGTGTGTGGAGG	MAPT	ENSG00000186868	0.8668431868856517	[26,20]	[22,6]	6	dCas9-VP64	positive selection	2529808
46178100	46178123	CHR_HSCHR17_1_CTG5	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTTTGGGAGGCCAAGGCAGAGG	MAPT	ENSG00000276155	-0.4547686614086857	[146,265]	[55,41]	-5	dCas9-VP64	positive selection	2557720
46026363	46026386	CHR_HSCHR17_2_CTG5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAGTCCCAGCTACTCCGG	MAPT	ENSG00000277956	0.2857588864060996	[349,998]	[76,442]	2	dCas9-VP64	positive selection	2563991
46014747	46014770	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAGTCCCAGCTACTCCGG	MAPT	ENSG00000186868	0.2857588864060996	[349,998]	[76,442]	2	dCas9-VP64	positive selection	2563992
45939564	45939587	CHR_HSCHR17_2_CTG5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGTTGCAGTGAGCCGAGATGG	MAPT	ENSG00000277956	0.34517561365305327	[29,16]	[7,9]	2	dCas9-VP64	positive selection	2572227
45927933	45927956	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGTTGCAGTGAGCCGAGATGG	MAPT	ENSG00000186868	0.34517561365305327	[29,16]	[7,9]	2	dCas9-VP64	positive selection	2572228
45987075	45987098	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	0.2652519401210793	[4,3]	[4,3]	5	hSpCas9	positive selection	3001325
45991476	45991499	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACGAAGATCGCCACACCGCGGGG	MAPT	ENSG00000186868	-0.9225916691145297	[2,3]	[1,0]	-9	hSpCas9	positive selection	3001326
45996408	45996431	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	-0.6918650422238656	[1,2]	[0,0]	-8	hSpCas9	positive selection	3001327
45962349	45962372	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	-0.10767762987698484	[3,4]	[4,1]	-1	hSpCas9	positive selection	3001328
45987075	45987098	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	0.31999470712150346	[4,4]	[4,3]	5	hSpCas9	positive selection	3069183
45991476	45991499	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACGAAGATCGCCACACCGCGGGG	MAPT	ENSG00000186868	0.060202124122364975	[2,2]	[2,1]	1	hSpCas9	positive selection	3069184
45996408	45996431	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	0.5688302000899536	[1,1]	[2,0]	8	hSpCas9	positive selection	3069185
45962349	45962372	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	0.22151037054352685	[3,3]	[4,2]	4	hSpCas9	positive selection	3069186
45996510	45996533		-	24336571	A375	resistance to PLX after 7 days	ACGGACCACTGCCACCTTCTTGG	MAPT	ENSG00000186868	0.02989738623234306	[180,187]	[179,194]	1	hSpCas9	positive selection	3126462
45996540	45996563		-	24336571	A375	resistance to PLX after 7 days	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.10387034887541713	[35,33]	[39,33]	3	hSpCas9	positive selection	3126463
45978406	45978429		-	24336571	A375	resistance to PLX after 7 days	GACCAGCAGCTTCGTCTTCCAGG	MAPT	ENSG00000186868	0.005601364645754892	[34,34]	[32,36]	0	hSpCas9	positive selection	3126464
45978419	45978442		+	24336571	A375	resistance to PLX after 7 days	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.06521673313997278	[18,18]	[20,18]	2	hSpCas9	positive selection	3126465
45971933	45971956		-	24336571	A375	resistance to PLX after 7 days	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	-0.1776856328284162	[30,33]	[25,30]	-5	hSpCas9	positive selection	3126466
45996510	45996533		-	24336571	A375	resistance to PLX after 14 days	ACGGACCACTGCCACCTTCTTGG	MAPT	ENSG00000186868	-0.49858966225280055	[196,192]	[66,60]	-6	hSpCas9	positive selection	3184255
45996540	45996563		-	24336571	A375	resistance to PLX after 14 days	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.31436877734264357	[34,31]	[11,11]	-4	hSpCas9	positive selection	3184256
45978406	45978429		-	24336571	A375	resistance to PLX after 14 days	GACCAGCAGCTTCGTCTTCCAGG	MAPT	ENSG00000186868	1.1053766677050378	[34,35]	[36,34]	8	hSpCas9	positive selection	3184257
45978419	45978442		+	24336571	A375	resistance to PLX after 14 days	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.37762569925543876	[19,21]	[10,14]	3	hSpCas9	positive selection	3184258
45971933	45971956		-	24336571	A375	resistance to PLX after 14 days	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.01648330006296117	[27,38]	[13,16]	0	hSpCas9	positive selection	3184259
45996510	45996533		-	24336571	A375	viability after 7 days	ACGGACCACTGCCACCTTCTTGG	MAPT	ENSG00000186868	0.6211679215274626	[125]	[180,187]	8	hSpCas9	negative selection	3242048
45996540	45996563		-	24336571	A375	viability after 7 days	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.08848540914777048	[33]	[35,33]	1	hSpCas9	negative selection	3242049
45978406	45978429		-	24336571	A375	viability after 7 days	GACCAGCAGCTTCGTCTTCCAGG	MAPT	ENSG00000186868	0.6463186771812296	[22]	[34,34]	8	hSpCas9	negative selection	3242050
45978419	45978442		+	24336571	A375	viability after 7 days	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.41096651782220023	[14]	[18,18]	6	hSpCas9	negative selection	3242051
45971933	45971956		-	24336571	A375	viability after 7 days	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.09392967019949361	[31]	[30,33]	1	hSpCas9	negative selection	3242052
45996510	45996533		-	24336571	A375	viability after 14 days	ACGGACCACTGCCACCTTCTTGG	MAPT	ENSG00000186868	0.7170042940065997	[125]	[196,192]	8	hSpCas9	negative selection	3299841
45996540	45996563		-	24336571	A375	viability after 14 days	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.04325727523387135	[33]	[34,31]	0	hSpCas9	negative selection	3299842
45978406	45978429		-	24336571	A375	viability after 14 days	GACCAGCAGCTTCGTCTTCCAGG	MAPT	ENSG00000186868	0.7035678479257369	[22]	[34,35]	8	hSpCas9	negative selection	3299843
45978419	45978442		+	24336571	A375	viability after 14 days	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.56964402674113	[14]	[19,21]	7	hSpCas9	negative selection	3299844
45971933	45971956		-	24336571	A375	viability after 14 days	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.1554864087051293	[31]	[27,38]	2	hSpCas9	negative selection	3299845
45971920	45971943	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	1.0675016525658179	[72,72]	[0,0]	5	hSpCas9	positive selection	3378546
45974383	45974406	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.25732621144583506	[127,127]	[0,0]	1	hSpCas9	positive selection	3378547
45987074	45987097	17	+	26780180	HT29	viability (Avana library 4 designs)	AAGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	1.60398487026577	[]	[]	6	hSpCas9	negative selection	3438971
45991475	45991498	17	+	26780180	HT29	viability (Avana library 4 designs)	ACGAAGATCGCCACACCGCGGGG	MAPT	ENSG00000186868	0.685872905868348	[]	[]	2	hSpCas9	negative selection	3438972
45996407	45996430	17	+	26780180	HT29	viability (Avana library 4 designs)	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	1.90684898819364	[]	[]	7	hSpCas9	negative selection	3438973
45962349	45962372	17	-	26780180	HT29	viability (Avana library 4 designs)	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	0.632983630686114	[]	[]	2	hSpCas9	negative selection	3438974
45996407	45996430	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	-5.1200125695776	[]	[]	-5	hSpCas9	negative selection	3528486
45991475	45991498	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACGAAGATCGCCACACCGCGGGG	MAPT	ENSG00000186868	3.64311045079048	[]	[]	6	hSpCas9	negative selection	3528487
45962349	45962372	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	-4.92613253511829	[]	[]	-5	hSpCas9	negative selection	3528488
45987074	45987097	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	-1.08603386621962	[]	[]	-1	hSpCas9	negative selection	3528489
45991574	45991597	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCTTCTTACCAGAGCTGGGTGG	MAPT	ENSG00000186868	-3.14234099587947	[]	[]	-4	hSpCas9	negative selection	3528490
45996397	45996420	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	-1.08183550943456	[]	[]	-1	hSpCas9	negative selection	3528491
45996407	45996430	17	+	26780180	A375	viability (Avana lentiGuide)	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	12.3417418884017	[]	[]	7	hSpCas9	negative selection	3637145
45991475	45991498	17	+	26780180	A375	viability (Avana lentiGuide)	ACGAAGATCGCCACACCGCGGGG	MAPT	ENSG00000186868	8.82049843264026	[]	[]	6	hSpCas9	negative selection	3637146
45962349	45962372	17	-	26780180	A375	viability (Avana lentiGuide)	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	6.49939980870509	[]	[]	5	hSpCas9	negative selection	3637147
45987074	45987097	17	+	26780180	A375	viability (Avana lentiGuide)	AAGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	1.2109734301205	[]	[]	1	hSpCas9	negative selection	3637148
45991574	45991597	17	-	26780180	A375	viability (Avana lentiGuide)	TTCTTCTTACCAGAGCTGGGTGG	MAPT	ENSG00000186868	0.952736642833367	[]	[]	1	hSpCas9	negative selection	3637149
45996397	45996420	17	+	26780180	A375	viability (Avana lentiGuide)	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	5.26739049753713	[]	[]	5	hSpCas9	negative selection	3637150
45996407	45996430	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	-1.0545897651956806	[3]	[2,0]	-9	hSpCas9	positive selection	3745804
45991475	45991498	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACGAAGATCGCCACACCGCGGGG	MAPT	ENSG00000186868	-0.035399550468152075	[4]	[5,3]	0	hSpCas9	positive selection	3745805
45962349	45962372	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	-0.6538704542677782	[5]	[3,1]	-7	hSpCas9	positive selection	3745806
45987074	45987097	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	0.014224332617613134	[5]	[6,5]	0	hSpCas9	positive selection	3745807
45991574	45991597	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCTTCTTACCAGAGCTGGGTGG	MAPT	ENSG00000186868	-0.06234361327274236	[5]	[5,4]	-1	hSpCas9	positive selection	3745808
45996397	45996420	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	-0.076205884524652	[4]	[3,4]	-1	hSpCas9	positive selection	3745809
45996407	45996430	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	-0.460722520344663	[4]	[2,2]	-5	hSpCas9	positive selection	3854411
45991475	45991498	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACGAAGATCGCCACACCGCGGGG	MAPT	ENSG00000186868	-1.467518496018852	[5]	[1,0]	-9	hSpCas9	positive selection	3854412
45962349	45962372	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	-0.28967258368984533	[6]	[2,5]	-4	hSpCas9	positive selection	3854413
45987074	45987097	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	0.2412978759054899	[5]	[6,5]	6	hSpCas9	positive selection	3854414
45991574	45991597	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCTTCTTACCAGAGCTGGGTGG	MAPT	ENSG00000186868	0.17140105952388335	[5]	[5,5]	4	hSpCas9	positive selection	3854415
45996397	45996420	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	-0.6866466531483173	[4]	[1,2]	-7	hSpCas9	positive selection	3854416
45974383	45974406	17	+	26780180	A375	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	1.29923298714591	[]	[]	7	hSpCas9	negative selection	3959939
45996407	45996430	17	-	26780180	A375	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.52330157825485	[]	[]	1	hSpCas9	negative selection	3959940
45996540	45996563	17	-	26780180	A375	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	1.14477528800706	[]	[]	6	hSpCas9	negative selection	3959941
45974433	45974456	17	-	26780180	A375	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	0.16061205234758	[]	[]	0	hSpCas9	negative selection	3959942
45971933	45971956	17	-	26780180	A375	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	1.32972677991972	[]	[]	7	hSpCas9	negative selection	3959943
45971920	45971943	17	+	26780180	A375	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	1.24279900233872	[]	[]	6	hSpCas9	negative selection	3959944
45974383	45974406	17	+	26780180	HT29	viability (GeCKOv2 library)	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	1.0277961022681	[]	[]	5	hSpCas9	negative selection	4067905
45996407	45996430	17	-	26780180	HT29	viability (GeCKOv2 library)	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.573837203833221	[]	[]	2	hSpCas9	negative selection	4067906
45996540	45996563	17	-	26780180	HT29	viability (GeCKOv2 library)	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.870913503634728	[]	[]	3	hSpCas9	negative selection	4067907
45974433	45974456	17	-	26780180	HT29	viability (GeCKOv2 library)	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	0.139721042031259	[]	[]	0	hSpCas9	negative selection	4067908
45971933	45971956	17	-	26780180	HT29	viability (GeCKOv2 library)	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	1.80475583324923	[]	[]	8	hSpCas9	negative selection	4067909
45971920	45971943	17	+	26780180	HT29	viability (GeCKOv2 library)	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	1.12367390182069	[]	[]	5	hSpCas9	negative selection	4067910
45996510	45996533	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGGACCACTGCCACCTTCTTGG	MAPT	ENSG00000186868	0.2906930166609959	[7]	[6,5]	7	hSpCas9	positive selection	4150682
45996540	45996563	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.05359406978194364	[4]	[3,3]	1	hSpCas9	positive selection	4150683
45978406	45978429	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACCAGCAGCTTCGTCTTCCAGG	MAPT	ENSG00000186868	0.279742351365311	[4]	[2,5]	7	hSpCas9	positive selection	4150684
45978419	45978442	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.1724709276870526	[4]	[2,3]	4	hSpCas9	positive selection	4150685
45971933	45971956	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.04134576373696841	[5]	[3,3]	1	hSpCas9	positive selection	4150686
45996510	45996533	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGGACCACTGCCACCTTCTTGG	MAPT	ENSG00000186868	1.0607086227336173	[7]	[7,7,7,6]	7	hSpCas9	positive selection	4214704
45996540	45996563	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	1.010094464858815	[5]	[5,5,2,4]	7	hSpCas9	positive selection	4214705
45978406	45978429	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACCAGCAGCTTCGTCTTCCAGG	MAPT	ENSG00000186868	0.7880730435493146	[4]	[4,3,1,2]	5	hSpCas9	positive selection	4214706
45978419	45978442	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.25494862627613013	[3]	[3,2,1,0]	2	hSpCas9	positive selection	4214707
45971933	45971956	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	-0.1390197415622676	[5]	[0,4,4,0]	-2	hSpCas9	positive selection	4214708
45996540	45996563	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.25689426663118625	[2]	[1,0]	-5	hSpCas9	positive selection	4281981
45971933	45971956	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	-0.09610506506441979	[2]	[1,1]	-2	hSpCas9	positive selection	4281982
45996407	45996430	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.5132337535471514	[2]	[2,3]	9	hSpCas9	positive selection	4281983
45974433	45974456	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	0.09393677585418048	[0]	[0,0]	2	hSpCas9	positive selection	4346239
45971920	45971943	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.4345170657955624	[2]	[2,0]	-7	hSpCas9	positive selection	4346240
45974383	45974406	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.09252537292804622	[2]	[2,1]	2	hSpCas9	positive selection	4346241
45962450	45962472	17	+	27760321	OCIAML3	viability	ACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.013526279756710002	[553,457]	[322,494]	0	hSpCas9	negative selection	4416835
45987027	45987049	17	+	27760321	OCIAML3	viability	TATATTTTATCAGCTCGCATGG	MAPT	ENSG00000186868	0.14996246238599012	[501,501]	[354,543]	1	hSpCas9	negative selection	4416836
45987052	45987074	17	+	27760321	OCIAML3	viability	GTAAAAGCAAAGACGGGACTGG	MAPT	ENSG00000186868	-1.0672709576146526	[170,146]	[56,61]	-7	hSpCas9	negative selection	4416837
45987075	45987097	17	+	27760321	OCIAML3	viability	AGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	0.13637589623662327	[154,133]	[76,184]	1	hSpCas9	negative selection	4416838
45991474	45991496	17	+	27760321	OCIAML3	viability	AACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.07898242760173119	[632,496]	[444,487]	0	hSpCas9	negative selection	4416839
45962450	45962472	17	+	27760321	OCIAML2	viability	ACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.2424973085026869	[553,457]	[428,551]	3	hSpCas9	negative selection	4500298
45987027	45987049	17	+	27760321	OCIAML2	viability	TATATTTTATCAGCTCGCATGG	MAPT	ENSG00000186868	0.766223447713362	[501,501]	[676,713]	9	hSpCas9	negative selection	4500299
45987052	45987074	17	+	27760321	OCIAML2	viability	GTAAAAGCAAAGACGGGACTGG	MAPT	ENSG00000186868	-0.15312186021202678	[170,146]	[107,124]	-2	hSpCas9	negative selection	4500300
45987075	45987097	17	+	27760321	OCIAML2	viability	AGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	0.09655756950373418	[154,133]	[112,139]	1	hSpCas9	negative selection	4500301
45991474	45991496	17	+	27760321	OCIAML2	viability	AACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.33133304894934873	[632,496]	[468,705]	4	hSpCas9	negative selection	4500302
45962450	45962472	17	+	27760321	MV411	viability	ACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.5757995797513787	[553,457]	[317,761]	4	hSpCas9	negative selection	4583761
45987027	45987049	17	+	27760321	MV411	viability	TATATTTTATCAGCTCGCATGG	MAPT	ENSG00000186868	0.9967643064342226	[501,501]	[695,613]	7	hSpCas9	negative selection	4583762
45987052	45987074	17	+	27760321	MV411	viability	GTAAAAGCAAAGACGGGACTGG	MAPT	ENSG00000186868	1.4504631143593427	[170,146]	[428,70]	9	hSpCas9	negative selection	4583763
45987075	45987097	17	+	27760321	MV411	viability	AGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	1.5755900086044632	[154,133]	[346,187]	9	hSpCas9	negative selection	4583764
45991474	45991496	17	+	27760321	MV411	viability	AACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.9315099370950162	[632,496]	[494,1023]	7	hSpCas9	negative selection	4583765
45962450	45962472	17	+	27760321	HL60	viability	ACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.4510511730368596	[553,457]	[628,491]	5	hSpCas9	negative selection	4667224
45987027	45987049	17	+	27760321	HL60	viability	TATATTTTATCAGCTCGCATGG	MAPT	ENSG00000186868	0.07527675127102015	[501,501]	[431,434]	0	hSpCas9	negative selection	4667225
45987052	45987074	17	+	27760321	HL60	viability	GTAAAAGCAAAGACGGGACTGG	MAPT	ENSG00000186868	-0.23074235722203817	[170,146]	[138,79]	-3	hSpCas9	negative selection	4667226
45987075	45987097	17	+	27760321	HL60	viability	AGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	0.34332303425975574	[154,133]	[160,136]	4	hSpCas9	negative selection	4667227
45991474	45991496	17	+	27760321	HL60	viability	AACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	-0.089642060694342	[632,496]	[409,452]	-1	hSpCas9	negative selection	4667228
45962450	45962472	17	+	27760321	HT1080	viability	ACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.5536588711304107	[457,357]	[229,247]	3	hSpCas9	negative selection	4750687
45987027	45987049	17	+	27760321	HT1080	viability	TATATTTTATCAGCTCGCATGG	MAPT	ENSG00000186868	1.069982083843501	[501,391]	[549,180]	6	hSpCas9	negative selection	4750688
45987052	45987074	17	+	27760321	HT1080	viability	GTAAAAGCAAAGACGGGACTGG	MAPT	ENSG00000186868	0.9515478294696456	[146,114]	[46,159]	5	hSpCas9	negative selection	4750689
45987075	45987097	17	+	27760321	HT1080	viability	AGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	0.9281885989721386	[133,104]	[113,64]	5	hSpCas9	negative selection	4750690
45991474	45991496	17	+	27760321	HT1080	viability	AACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	1.6737931894857518	[496,387]	[697,413]	8	hSpCas9	negative selection	4750691
45962450	45962472	17	+	27760321	HT29	viability after 7 days	ACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.6844569583536882	[457,357]	[838,732,951]	9	hSpCas9	negative selection	4834150
45987027	45987049	17	+	27760321	HT29	viability after 7 days	TATATTTTATCAGCTCGCATGG	MAPT	ENSG00000186868	-0.7910102519791504	[501,391]	[435,375,202]	-8	hSpCas9	negative selection	4834151
45987052	45987074	17	+	27760321	HT29	viability after 7 days	GTAAAAGCAAAGACGGGACTGG	MAPT	ENSG00000186868	-0.394078858156824	[146,114]	[183,132,76]	-5	hSpCas9	negative selection	4834152
45987075	45987097	17	+	27760321	HT29	viability after 7 days	AGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	0.23372123839462544	[133,104]	[192,213,137]	3	hSpCas9	negative selection	4834153
45991474	45991496	17	+	27760321	HT29	viability after 7 days	AACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.31880759674247866	[496,387]	[722,862,548]	5	hSpCas9	negative selection	4834154
45962450	45962472	17	+	27760321	HT29	viability after 25 days	ACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.548967262244668	[457,357]	[828,640,552]	6	hSpCas9	negative selection	4917613
45987027	45987049	17	+	27760321	HT29	viability after 25 days	TATATTTTATCAGCTCGCATGG	MAPT	ENSG00000186868	-0.5131436883873374	[501,391]	[372,404,286]	-5	hSpCas9	negative selection	4917614
45987052	45987074	17	+	27760321	HT29	viability after 25 days	GTAAAAGCAAAGACGGGACTGG	MAPT	ENSG00000186868	0.47691173627674865	[146,114]	[191,146,295]	5	hSpCas9	negative selection	4917615
45987075	45987097	17	+	27760321	HT29	viability after 25 days	AGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	-0.31031875014551935	[133,104]	[79,143,107]	-3	hSpCas9	negative selection	4917616
45991474	45991496	17	+	27760321	HT29	viability after 25 days	AACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.3963448479422604	[496,387]	[616,645,743]	4	hSpCas9	negative selection	4917617
45962450	45962472	17	+	27760321	HT29	viability after 22 days	ACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.8131873811064141	[457,357]	[969,858,651]	8	hSpCas9	negative selection	5001076
45987027	45987049	17	+	27760321	HT29	viability after 22 days	TATATTTTATCAGCTCGCATGG	MAPT	ENSG00000186868	-0.7616461014037474	[501,391]	[246,359,308]	-6	hSpCas9	negative selection	5001077
45987052	45987074	17	+	27760321	HT29	viability after 22 days	GTAAAAGCAAAGACGGGACTGG	MAPT	ENSG00000186868	-0.9920603075988161	[146,114]	[85,84,56]	-6	hSpCas9	negative selection	5001078
45987075	45987097	17	+	27760321	HT29	viability after 22 days	AGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	-0.2847358937148674	[133,104]	[114,137,86]	-3	hSpCas9	negative selection	5001079
45991474	45991496	17	+	27760321	HT29	viability after 22 days	AACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.37202747888712057	[496,387]	[657,584,743]	4	hSpCas9	negative selection	5001080
45962450	45962472	17	+	27760321	HT29	viability after 19 days	ACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.9284095230469145	[457,357]	[860,1206,603]	8	hSpCas9	negative selection	5084539
45987027	45987049	17	+	27760321	HT29	viability after 19 days	TATATTTTATCAGCTCGCATGG	MAPT	ENSG00000186868	-1.092553233142051	[501,391]	[366,222,145]	-6	hSpCas9	negative selection	5084540
45987052	45987074	17	+	27760321	HT29	viability after 19 days	GTAAAAGCAAAGACGGGACTGG	MAPT	ENSG00000186868	-0.8575732340250783	[146,114]	[218,32,12]	-6	hSpCas9	negative selection	5084541
45987075	45987097	17	+	27760321	HT29	viability after 19 days	AGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	0.5083135677400323	[133,104]	[286,301,10]	5	hSpCas9	negative selection	5084542
45991474	45991496	17	+	27760321	HT29	viability after 19 days	AACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.3835373872360676	[496,387]	[837,827,344]	3	hSpCas9	negative selection	5084543
45962450	45962472	17	+	27760321	HT29	viability after 16 days	ACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.019825686137264847	[457,357]	[416,542,421]	0	hSpCas9	negative selection	5168002
45987027	45987049	17	+	27760321	HT29	viability after 16 days	TATATTTTATCAGCTCGCATGG	MAPT	ENSG00000186868	-0.18463604052211258	[501,391]	[460,249,615]	-2	hSpCas9	negative selection	5168003
45987052	45987074	17	+	27760321	HT29	viability after 16 days	GTAAAAGCAAAGACGGGACTGG	MAPT	ENSG00000186868	-0.7862949399105936	[146,114]	[207,30,28]	-6	hSpCas9	negative selection	5168004
45987075	45987097	17	+	27760321	HT29	viability after 16 days	AGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	0.6090313545098823	[133,104]	[375,93,160]	7	hSpCas9	negative selection	5168005
45991474	45991496	17	+	27760321	HT29	viability after 16 days	AACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.036174317565013714	[496,387]	[544,407,575]	0	hSpCas9	negative selection	5168006
45962450	45962472	17	+	27760321	HT29	viability after 13 days	ACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.23921060723171847	[457,357]	[544,569,560]	3	hSpCas9	negative selection	5251465
45987027	45987049	17	+	27760321	HT29	viability after 13 days	TATATTTTATCAGCTCGCATGG	MAPT	ENSG00000186868	-0.23882863847975655	[501,391]	[341,595,383]	-3	hSpCas9	negative selection	5251466
45987052	45987074	17	+	27760321	HT29	viability after 13 days	GTAAAAGCAAAGACGGGACTGG	MAPT	ENSG00000186868	-0.50585808785394	[146,114]	[99,111,108]	-5	hSpCas9	negative selection	5251467
45987075	45987097	17	+	27760321	HT29	viability after 13 days	AGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	0.4956066089224267	[133,104]	[252,199,136]	6	hSpCas9	negative selection	5251468
45991474	45991496	17	+	27760321	HT29	viability after 13 days	AACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.0890019766625535	[496,387]	[629,584,429]	1	hSpCas9	negative selection	5251469
45962450	45962472	17	+	27760321	HT29	viability after 10 days	ACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.6656219555885822	[457,357]	[780,754,884]	8	hSpCas9	negative selection	5334928
45987027	45987049	17	+	27760321	HT29	viability after 10 days	TATATTTTATCAGCTCGCATGG	MAPT	ENSG00000186868	-0.6663470812454623	[501,391]	[200,479,376]	-7	hSpCas9	negative selection	5334929
45987052	45987074	17	+	27760321	HT29	viability after 10 days	GTAAAAGCAAAGACGGGACTGG	MAPT	ENSG00000186868	-0.48101841829788694	[146,114]	[119,63,164]	-5	hSpCas9	negative selection	5334930
45987075	45987097	17	+	27760321	HT29	viability after 10 days	AGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	-0.33040511738370815	[133,104]	[166,115,73]	-4	hSpCas9	negative selection	5334931
45991474	45991496	17	+	27760321	HT29	viability after 10 days	AACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.04210267836370979	[496,387]	[499,529,672]	0	hSpCas9	negative selection	5334932
45962450	45962472	17	+	27760321	MOLM13	viability	ACACGGACGCTGGCCTGAAAGG	MAPT	ENSG00000186868	0.8005433320640929	[553,457]	[689,328]	5	hSpCas9	negative selection	5418391
45987027	45987049	17	+	27760321	MOLM13	viability	TATATTTTATCAGCTCGCATGG	MAPT	ENSG00000186868	0.4051904611183734	[501,501]	[452,310]	3	hSpCas9	negative selection	5418392
45987052	45987074	17	+	27760321	MOLM13	viability	GTAAAAGCAAAGACGGGACTGG	MAPT	ENSG00000186868	-0.7706285373851851	[170,146]	[86,22]	-5	hSpCas9	negative selection	5418393
45987075	45987097	17	+	27760321	MOLM13	viability	AGCGATGACAAAAAAGCCAAGG	MAPT	ENSG00000186868	0.0832360072529188	[154,133]	[164,18]	0	hSpCas9	negative selection	5418394
45991474	45991496	17	+	27760321	MOLM13	viability	AACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	1.119052407522778	[632,496]	[770,616]	7	hSpCas9	negative selection	5418395
45894956	45894979	17	+	27661255	K562	viability	GGAGGCTGTGCCGGCAGGGTGGG	MAPT	ENSG00000186868	0.17348946762688508	[803,867]	[750,752]	6	dCas9-KRAB	negative selection	5492297
45894978	45895001	17	+	27661255	K562	viability	GGCGCGGCGGCGGTGACTTGGGG	MAPT	ENSG00000186868	0.44183427418055987	[301,377]	[381,354]	9	dCas9-KRAB	negative selection	5492298
45894583	45894606	17	-	27661255	K562	viability	GGTGGCAGCGGCGCTGCTGTTGG	MAPT	ENSG00000186868	0.31030681843267555	[744,675]	[745,669]	8	dCas9-KRAB	negative selection	5492299
45996540	45996563	17	-	27260156	BXPC3	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.22469068655636604	[213]	[199,191,215,150]	-5	hSpCas9	negative selection	5554441
45971933	45971956	17	-	27260156	BXPC3	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.4002964915043902	[207]	[246,320,305,272]	8	hSpCas9	negative selection	5554442
45996407	45996430	17	-	27260156	BXPC3	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.774049546971176	[368]	[633,579,744,687]	9	hSpCas9	negative selection	5554443
45974433	45974456	17	-	27260156	BXPC3	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	0.10860187827442047	[10]	[33,6,2,1]	2	hSpCas9	negative selection	5618699
45971920	45971943	17	+	27260156	BXPC3	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.027394316729180468	[275]	[271,279,298,280]	0	hSpCas9	negative selection	5618700
45974383	45974406	17	+	27260156	BXPC3	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	-0.07237679007659054	[358]	[316,384,429,288]	-2	hSpCas9	negative selection	5618701
45996540	45996563	17	-	27260156	A673	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.1178031156688899	[213]	[383,194,272,276]	3	hSpCas9	negative selection	5675692
45971933	45971956	17	-	27260156	A673	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.4677082058409042	[207]	[426,277,327,359]	9	hSpCas9	negative selection	5675693
45996407	45996430	17	-	27260156	A673	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.5033500425277646	[368]	[671,572,677,591]	9	hSpCas9	negative selection	5675694
45974433	45974456	17	-	27260156	A673	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	0.371790196810287	[10]	[9,10,22,23]	8	hSpCas9	negative selection	5739950
45971920	45971943	17	+	27260156	A673	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	0.16334997124460404	[275]	[370,350,450,306]	4	hSpCas9	negative selection	5739951
45974383	45974406	17	+	27260156	A673	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.0568872683450905	[358]	[464,460,427,439]	1	hSpCas9	negative selection	5739952
45996540	45996563	17	-	27260156	A375	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.09171395999282228	[213]	[247,378,266,81]	-1	hSpCas9	negative selection	5796943
45971933	45971956	17	-	27260156	A375	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.35269431773252435	[207]	[278,495,352,155]	5	hSpCas9	negative selection	5796944
45996407	45996430	17	-	27260156	A375	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.5436465849530053	[368]	[621,699,741,474]	7	hSpCas9	negative selection	5796945
45974433	45974456	17	-	27260156	A375	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-3.036601760901835	[10]	[0,0,0,2]	-9	hSpCas9	negative selection	5861201
45971920	45971943	17	+	27260156	A375	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.7210995558786079	[275]	[234,159,187,193]	-7	hSpCas9	negative selection	5861202
45974383	45974406	17	+	27260156	A375	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.22317961835689906	[358]	[396,702,432,455]	3	hSpCas9	negative selection	5861203
45996540	45996563	17	-	27260156	COLO741	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.18469806772738806	[213]	[280,362,286]	4	hSpCas9	negative selection	5918194
45971933	45971956	17	-	27260156	COLO741	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.26431769935755667	[207]	[328,271,353]	5	hSpCas9	negative selection	5918195
45996407	45996430	17	-	27260156	COLO741	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.561968069638278	[368]	[753,817,531]	9	hSpCas9	negative selection	5918196
45974433	45974456	17	-	27260156	COLO741	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-1.8765961033869232	[10]	[1,0,7]	-9	hSpCas9	negative selection	5982452
45971920	45971943	17	+	27260156	COLO741	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.02061803812898888	[275]	[320,385,333]	0	hSpCas9	negative selection	5982453
45974383	45974406	17	+	27260156	COLO741	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.014081729922196362	[358]	[573,475,355]	0	hSpCas9	negative selection	5982454
45996540	45996563	17	-	27260156	CAL120	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.31277471117633304	[213]	[193,285,160]	-4	hSpCas9	negative selection	6039445
45971933	45971956	17	-	27260156	CAL120	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.16021201361148196	[207]	[179,317,351]	2	hSpCas9	negative selection	6039446
45996407	45996430	17	-	27260156	CAL120	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.5965515813723014	[368]	[1060,334,740]	8	hSpCas9	negative selection	6039447
45974433	45974456	17	-	27260156	CAL120	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-1.7233934271330025	[10]	[0,8,1]	-9	hSpCas9	negative selection	6103703
45971920	45971943	17	+	27260156	CAL120	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-1.1726630315467679	[275]	[258,58,154]	-9	hSpCas9	negative selection	6103704
45974383	45974406	17	+	27260156	CAL120	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.21324601547036443	[358]	[311,552,654]	3	hSpCas9	negative selection	6103705
45996540	45996563	17	-	27260156	CADOES1	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.1620707115321418	[213]	[168,295,89,155]	-3	hSpCas9	negative selection	6160696
45971933	45971956	17	-	27260156	CADOES1	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.6886080357771823	[207]	[464,315,174,289]	9	hSpCas9	negative selection	6160697
45996407	45996430	17	-	27260156	CADOES1	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.6216327201352028	[368]	[604,462,485,558]	8	hSpCas9	negative selection	6160698
45974433	45974456	17	-	27260156	CADOES1	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-0.13117027966664097	[10]	[1,3,5,25]	-2	hSpCas9	negative selection	6224954
45971920	45971943	17	+	27260156	CADOES1	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.1416544098092295	[275]	[199,209,307,211]	-2	hSpCas9	negative selection	6224955
45974383	45974406	17	+	27260156	CADOES1	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.12958778662302933	[358]	[395,322,297,446]	2	hSpCas9	negative selection	6224956
45996540	45996563	17	-	27260156	EWS502	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.27429448117118505	[213]	[295,249,285,260]	5	hSpCas9	negative selection	6281947
45971933	45971956	17	-	27260156	EWS502	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.5128808432557727	[207]	[177,252,344,513]	8	hSpCas9	negative selection	6281948
45996407	45996430	17	-	27260156	EWS502	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.6936377314202611	[368]	[617,756,497,648]	9	hSpCas9	negative selection	6281949
45974433	45974456	17	-	27260156	EWS502	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-0.4009137889634182	[10]	[10,2,0,20]	-6	hSpCas9	negative selection	6346205
45971920	45971943	17	+	27260156	EWS502	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	0.04011709114369921	[275]	[211,292,370,339]	0	hSpCas9	negative selection	6346206
45974383	45974406	17	+	27260156	EWS502	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.08222082124422703	[358]	[328,389,535,361]	1	hSpCas9	negative selection	6346207
45996540	45996563	17	-	27260156	EW8	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.5117685542138177	[213]	[124,141,59,169]	-7	hSpCas9	negative selection	6403198
45971933	45971956	17	-	27260156	EW8	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.26805815631615326	[207]	[191,210,143,272]	5	hSpCas9	negative selection	6403199
45996407	45996430	17	-	27260156	EW8	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.6680581829430652	[368]	[559,493,510,337]	9	hSpCas9	negative selection	6403200
45974433	45974456	17	-	27260156	EW8	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	0.9598048268555521	[10]	[0,14,43,2]	9	hSpCas9	negative selection	6467456
45971920	45971943	17	+	27260156	EW8	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	0.005984233644624637	[275]	[119,217,139,421]	0	hSpCas9	negative selection	6467457
45974383	45974406	17	+	27260156	EW8	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	-0.033236850680974706	[358]	[258,290,251,336]	0	hSpCas9	negative selection	6467458
45996540	45996563	17	-	27260156	CORL105	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.19616628224699562	[213]	[176,225,237,234]	-4	hSpCas9	negative selection	6524449
45971933	45971956	17	-	27260156	CORL105	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.28003014754217737	[207]	[296,195,500,222]	5	hSpCas9	negative selection	6524450
45996407	45996430	17	-	27260156	CORL105	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.28202901707821937	[368]	[669,375,545,519]	5	hSpCas9	negative selection	6524451
45974433	45974456	17	-	27260156	CORL105	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	0.518817294993096	[10]	[11,12,26,22]	8	hSpCas9	negative selection	6588707
45971920	45971943	17	+	27260156	CORL105	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.5874532509963201	[275]	[324,209,193,131]	-8	hSpCas9	negative selection	6588708
45974383	45974406	17	+	27260156	CORL105	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	-0.3853979389190214	[358]	[293,381,234,359]	-6	hSpCas9	negative selection	6588709
45996540	45996563	17	-	27260156	HS294T	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.483796316487632	[213]	[55,56,58,65]	-6	hSpCas9	negative selection	6645700
45971933	45971956	17	-	27260156	HS294T	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.29921665509945083	[207]	[107,121,78,81]	4	hSpCas9	negative selection	6645701
45996407	45996430	17	-	27260156	HS294T	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.777740035469076	[368]	[187,312,248,227]	8	hSpCas9	negative selection	6645702
45974433	45974456	17	-	27260156	HS294T	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-0.7249804768430232	[10]	[2,1,3,0]	-8	hSpCas9	negative selection	6709958
45971920	45971943	17	+	27260156	HS294T	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-1.0163843998042963	[275]	[42,47,67,52]	-9	hSpCas9	negative selection	6709959
45974383	45974406	17	+	27260156	HS294T	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	-0.1172117980984081	[358]	[102,139,124,148]	-2	hSpCas9	negative selection	6709960
45996540	45996563	17	-	27260156	HCC44	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.0015744750074884184	[213]	[310,149,315,222]	0	hSpCas9	negative selection	6766951
45971933	45971956	17	-	27260156	HCC44	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.26062486445856725	[207]	[262,277,290,292]	4	hSpCas9	negative selection	6766952
45996407	45996430	17	-	27260156	HCC44	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.4132034427285278	[368]	[565,537,682,459]	6	hSpCas9	negative selection	6766953
45974433	45974456	17	-	27260156	HCC44	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	0.3864804037411931	[10]	[51,0,16,0]	6	hSpCas9	negative selection	6831209
45971920	45971943	17	+	27260156	HCC44	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.5974123208336032	[275]	[122,314,180,177]	-7	hSpCas9	negative selection	6831210
45974383	45974406	17	+	27260156	HCC44	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.08629913810913242	[358]	[499,385,511,351]	1	hSpCas9	negative selection	6831211
45996540	45996563	17	-	27260156	G402	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.241186646717783	[213]	[340,210,219,131]	-3	hSpCas9	negative selection	6888202
45971933	45971956	17	-	27260156	G402	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.6366979918877272	[207]	[384,266,307,597]	7	hSpCas9	negative selection	6888203
45996407	45996430	17	-	27260156	G402	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	1.0110880554527568	[368]	[1370,493,849,951]	9	hSpCas9	negative selection	6888204
45974433	45974456	17	-	27260156	G402	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-1.0642138363293947	[10]	[11,11,0,1]	-8	hSpCas9	negative selection	6952460
45971920	45971943	17	+	27260156	G402	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.6280160253025212	[275]	[159,108,408,179]	-6	hSpCas9	negative selection	6952461
45974383	45974406	17	+	27260156	G402	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.07965709877245358	[358]	[473,471,442,462]	1	hSpCas9	negative selection	6952462
45996540	45996563	17	-	27260156	L33	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.21784603167161365	[213]	[232,112,155,238]	5	hSpCas9	negative selection	7009453
45971933	45971956	17	-	27260156	L33	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.04457011325538218	[207]	[222,92,124,208]	1	hSpCas9	negative selection	7009454
45996407	45996430	17	-	27260156	L33	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.6278128254716648	[368]	[662,228,316,551]	9	hSpCas9	negative selection	7009455
45974433	45974456	17	-	27260156	L33	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-1.9184097904485053	[10]	[3,0,1,1]	-9	hSpCas9	negative selection	7073711
45971920	45971943	17	+	27260156	L33	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.6903673919242327	[275]	[128,77,140,141]	-9	hSpCas9	negative selection	7073712
45974383	45974406	17	+	27260156	L33	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.031121487641044998	[358]	[297,160,239,395]	0	hSpCas9	negative selection	7073713
45996540	45996563	17	-	27260156	K562	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.4281347315911014	[213]	[183,189,318,311]	5	hSpCas9	negative selection	7130704
45971933	45971956	17	-	27260156	K562	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	1.1580240489129658	[207]	[363,406,508,366]	9	hSpCas9	negative selection	7130705
45996407	45996430	17	-	27260156	K562	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.41183551024529086	[368]	[204,572,363,570]	5	hSpCas9	negative selection	7130706
45974433	45974456	17	-	27260156	K562	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-3.2855817865610106	[10]	[0,0,0,0]	-9	hSpCas9	negative selection	7194962
45971920	45971943	17	+	27260156	K562	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	0.06313700437672864	[275]	[173,400,188,258]	0	hSpCas9	negative selection	7194963
45974383	45974406	17	+	27260156	K562	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	-0.2965513480164029	[358]	[470,296,124,172]	-4	hSpCas9	negative selection	7194964
45996540	45996563	17	-	27260156	HT29	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.15359173043961893	[213]	[308,458,244,172]	3	hSpCas9	negative selection	7251955
45971933	45971956	17	-	27260156	HT29	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.43302931929339117	[207]	[401,381,226,357]	8	hSpCas9	negative selection	7251956
45996407	45996430	17	-	27260156	HT29	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.6120847484180167	[368]	[664,905,616,579]	9	hSpCas9	negative selection	7251957
45974433	45974456	17	-	27260156	HT29	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-0.01865871488501103	[10]	[0,0,46,2]	0	hSpCas9	negative selection	7316213
45971920	45971943	17	+	27260156	HT29	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	0.08687385128470271	[275]	[283,347,432,351]	1	hSpCas9	negative selection	7316214
45974383	45974406	17	+	27260156	HT29	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	-0.05513144233293127	[358]	[440,466,374,401]	-1	hSpCas9	negative selection	7316215
45996540	45996563	17	-	27260156	MHHES1	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.012556833472190831	[213]	[174,243,359,178]	0	hSpCas9	negative selection	7373206
45971933	45971956	17	-	27260156	MHHES1	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.30672054128452186	[207]	[253,313,502,120]	5	hSpCas9	negative selection	7373207
45996407	45996430	17	-	27260156	MHHES1	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.5303308039371373	[368]	[747,585,622,475]	8	hSpCas9	negative selection	7373208
45974433	45974456	17	-	27260156	MHHES1	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-1.8862709228066956	[10]	[5,0,0,4]	-9	hSpCas9	negative selection	7437464
45971920	45971943	17	+	27260156	MHHES1	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.2070130205291384	[275]	[221,358,324,187]	-4	hSpCas9	negative selection	7437465
45974383	45974406	17	+	27260156	MHHES1	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.4943014462353789	[358]	[468,438,642,665]	8	hSpCas9	negative selection	7437466
45996540	45996563	17	-	27260156	MEWO	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.23006238159822634	[213]	[271,105,153]	-5	hSpCas9	negative selection	7494457
45971933	45971956	17	-	27260156	MEWO	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.1625347356190152	[207]	[194,205,247]	3	hSpCas9	negative selection	7494458
45996407	45996430	17	-	27260156	MEWO	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.46339525835746675	[368]	[410,529,473]	8	hSpCas9	negative selection	7494459
45974433	45974456	17	-	27260156	MEWO	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-0.015556874852466152	[10]	[1,0,25]	0	hSpCas9	negative selection	7558715
45971920	45971943	17	+	27260156	MEWO	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.06497741598000173	[275]	[378,262,123]	-1	hSpCas9	negative selection	7558716
45974383	45974406	17	+	27260156	MEWO	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.04886308098145625	[358]	[473,296,295]	1	hSpCas9	negative selection	7558717
45996540	45996563	17	-	27260156	LNCAPCLONEFGC	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.21924171121927105	[213]	[145,137,157,224]	-3	hSpCas9	negative selection	7615708
45971933	45971956	17	-	27260156	LNCAPCLONEFGC	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.6729836406747377	[207]	[334,220,387,274]	9	hSpCas9	negative selection	7615709
45996407	45996430	17	-	27260156	LNCAPCLONEFGC	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.8128729922154319	[368]	[540,511,699,617]	9	hSpCas9	negative selection	7615710
45974433	45974456	17	-	27260156	LNCAPCLONEFGC	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	0.9611274789337401	[10]	[22,0,0,50]	9	hSpCas9	negative selection	7679966
45971920	45971943	17	+	27260156	LNCAPCLONEFGC	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.11001881880990283	[275]	[199,234,245,247]	-2	hSpCas9	negative selection	7679967
45974383	45974406	17	+	27260156	LNCAPCLONEFGC	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	-0.0017759140187685318	[358]	[364,233,410,306]	0	hSpCas9	negative selection	7679968
45996540	45996563	17	-	27260156	PANC0327	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.16055607638690006	[213]	[61,196,223,184]	-2	hSpCas9	negative selection	7736959
45971933	45971956	17	-	27260156	PANC0327	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.08143976967538324	[207]	[179,225,305,64]	1	hSpCas9	negative selection	7736960
45996407	45996430	17	-	27260156	PANC0327	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.46645667228548415	[368]	[601,375,591,263]	7	hSpCas9	negative selection	7736961
45974433	45974456	17	-	27260156	PANC0327	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-2.970302355858001	[10]	[0,0,1,0]	-9	hSpCas9	negative selection	7801217
45971920	45971943	17	+	27260156	PANC0327	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.7451066697212142	[275]	[237,87,96,176]	-7	hSpCas9	negative selection	7801218
45974383	45974406	17	+	27260156	PANC0327	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.7047646043838067	[358]	[506,475,732,367]	8	hSpCas9	negative selection	7801219
45996540	45996563	17	-	27260156	NCIH2009	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.101330501697247	[213]	[281,350,201]	-1	hSpCas9	negative selection	7858210
45971933	45971956	17	-	27260156	NCIH2009	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.29791515606873786	[207]	[523,254,326]	4	hSpCas9	negative selection	7858211
45996407	45996430	17	-	27260156	NCIH2009	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.8081860827245666	[368]	[908,1117,676]	9	hSpCas9	negative selection	7858212
45974433	45974456	17	-	27260156	NCIH2009	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	0.23810016316831017	[10]	[1,26,21]	3	hSpCas9	negative selection	7922468
45971920	45971943	17	+	27260156	NCIH2009	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.7602799291120462	[275]	[259,281,145]	-7	hSpCas9	negative selection	7922469
45974383	45974406	17	+	27260156	NCIH2009	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	-0.2494782518164278	[358]	[449,455,363]	-3	hSpCas9	negative selection	7922470
45996540	45996563	17	-	27260156	NCIH1373	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.3560654963600356	[213]	[559,268,153,75]	3	hSpCas9	negative selection	7979461
45971933	45971956	17	-	27260156	NCIH1373	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	-0.3234560956295993	[207]	[232,109,211,53]	-3	hSpCas9	negative selection	7979462
45996407	45996430	17	-	27260156	NCIH1373	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.9318112724748069	[368]	[1018,573,650,257]	8	hSpCas9	negative selection	7979463
45974433	45974456	17	-	27260156	NCIH1373	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-1.8599054470177974	[10]	[0,1,2,1]	-9	hSpCas9	negative selection	8043719
45971920	45971943	17	+	27260156	NCIH1373	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-1.4156215472465696	[275]	[42,257,43,23]	-8	hSpCas9	negative selection	8043720
45974383	45974406	17	+	27260156	NCIH1373	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.2291126972691217	[358]	[417,510,207,198]	2	hSpCas9	negative selection	8043721
45996540	45996563	17	-	27260156	PATU8902	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.9183218536256579	[213]	[227,251,97,53]	-7	hSpCas9	negative selection	8100712
45971933	45971956	17	-	27260156	PATU8902	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.7898143222063074	[207]	[237,665,494,619]	8	hSpCas9	negative selection	8100713
45996407	45996430	17	-	27260156	PATU8902	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.6967225494256037	[368]	[965,446,721,1267]	7	hSpCas9	negative selection	8100714
45974433	45974456	17	-	27260156	PATU8902	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-2.263153147601191	[10]	[2,0,0,8]	-9	hSpCas9	negative selection	8164970
45971920	45971943	17	+	27260156	PATU8902	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.17183587714977133	[275]	[98,176,672,327]	-2	hSpCas9	negative selection	8164971
45974383	45974406	17	+	27260156	PATU8902	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	-0.08089960032373766	[358]	[776,506,175,503]	-1	hSpCas9	negative selection	8164972
45996540	45996563	17	-	27260156	PANC1	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.07774866902690003	[213]	[151,219,86,300]	1	hSpCas9	negative selection	8221963
45971933	45971956	17	-	27260156	PANC1	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.027027851633385724	[207]	[133,220,188,188]	0	hSpCas9	negative selection	8221964
45996407	45996430	17	-	27260156	PANC1	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.5309110178602108	[368]	[312,585,484,467]	8	hSpCas9	negative selection	8221965
45974433	45974456	17	-	27260156	PANC1	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-1.2255864955298197	[10]	[0,8,1,4]	-9	hSpCas9	negative selection	8286221
45971920	45971943	17	+	27260156	PANC1	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.24586355218076605	[275]	[185,244,262,124]	-4	hSpCas9	negative selection	8286222
45974383	45974406	17	+	27260156	PANC1	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.019484370988097244	[358]	[343,317,349,244]	0	hSpCas9	negative selection	8286223
45996540	45996563	17	-	27260156	PANC0813	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.023891632460745882	[213]	[275,308,196,210]	0	hSpCas9	negative selection	8343214
45971933	45971956	17	-	27260156	PANC0813	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.5945776641986902	[207]	[491,381,278,334]	8	hSpCas9	negative selection	8343215
45996407	45996430	17	-	27260156	PANC0813	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.6850689364769944	[368]	[785,520,736,747]	9	hSpCas9	negative selection	8343216
45974433	45974456	17	-	27260156	PANC0813	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-0.8240981077739553	[10]	[15,0,5,6]	-8	hSpCas9	negative selection	8407472
45971920	45971943	17	+	27260156	PANC0813	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.8951680008433484	[275]	[164,121,175,229]	-8	hSpCas9	negative selection	8407473
45974383	45974406	17	+	27260156	PANC0813	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.22672166058981646	[358]	[453,351,819,352]	3	hSpCas9	negative selection	8407474
45996540	45996563	17	-	27260156	RDES	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.503658132414835	[213]	[133,147,167,263]	-7	hSpCas9	negative selection	8464465
45971933	45971956	17	-	27260156	RDES	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.4727162149385057	[207]	[280,374,262,414]	7	hSpCas9	negative selection	8464466
45996407	45996430	17	-	27260156	RDES	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.7989590529935673	[368]	[636,596,785,985]	9	hSpCas9	negative selection	8464467
45974433	45974456	17	-	27260156	RDES	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-1.6344261705108165	[10]	[3,5,0,4]	-9	hSpCas9	negative selection	8528723
45971920	45971943	17	+	27260156	RDES	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.5313105536806567	[275]	[188,272,214,190]	-7	hSpCas9	negative selection	8528724
45974383	45974406	17	+	27260156	RDES	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	-0.13256003487437218	[358]	[327,371,352,464]	-2	hSpCas9	negative selection	8528725
45996540	45996563	17	-	27260156	PC3	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.20925987422766756	[213]	[115,287,461,239]	4	hSpCas9	negative selection	8585716
45971933	45971956	17	-	27260156	PC3	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.4601259961690054	[207]	[241,212,493,258]	8	hSpCas9	negative selection	8585717
45996407	45996430	17	-	27260156	PC3	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.4940848216585815	[368]	[277,587,747,607]	8	hSpCas9	negative selection	8585718
45974433	45974456	17	-	27260156	PC3	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	0.37927939293806023	[10]	[14,0,0,33]	7	hSpCas9	negative selection	8649974
45971920	45971943	17	+	27260156	PC3	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.672904563818762	[275]	[96,162,358,161]	-9	hSpCas9	negative selection	8649975
45974383	45974406	17	+	27260156	PC3	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.11609508075395608	[358]	[215,282,976,351]	2	hSpCas9	negative selection	8649976
45996540	45996563	17	-	27260156	PATU8988T	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.6300338759231932	[213]	[126,210,95,105]	-7	hSpCas9	negative selection	8706967
45971933	45971956	17	-	27260156	PATU8988T	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.07869735808786249	[207]	[200,216,241,186]	1	hSpCas9	negative selection	8706968
45996407	45996430	17	-	27260156	PATU8988T	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.8950353576961966	[368]	[403,944,710,613]	9	hSpCas9	negative selection	8706969
45974433	45974456	17	-	27260156	PATU8988T	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	1.083612303193192	[10]	[0,16,1,73]	9	hSpCas9	negative selection	8771225
45971920	45971943	17	+	27260156	PATU8988T	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	0.04799028727676313	[275]	[350,134,355,243]	0	hSpCas9	negative selection	8771226
45974383	45974406	17	+	27260156	PATU8988T	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.33718206346868124	[358]	[547,373,343,485]	6	hSpCas9	negative selection	8771227
45996540	45996563	17	-	27260156	T47D	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.002708970926512455	[213]	[262,210,257,270]	0	hSpCas9	negative selection	8828218
45971933	45971956	17	-	27260156	T47D	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.4108060609133336	[207]	[326,295,332,334]	8	hSpCas9	negative selection	8828219
45996407	45996430	17	-	27260156	T47D	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.5295001869381363	[368]	[675,635,605,560]	9	hSpCas9	negative selection	8828220
45974433	45974456	17	-	27260156	T47D	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-0.9157064994131741	[10]	[1,7,9,6]	-9	hSpCas9	negative selection	8892476
45971920	45971943	17	+	27260156	T47D	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.20220974541006065	[275]	[304,224,295,296]	-4	hSpCas9	negative selection	8892477
45974383	45974406	17	+	27260156	T47D	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	-0.1424382922435573	[358]	[316,400,369,426]	-3	hSpCas9	negative selection	8892478
45996540	45996563	17	-	27260156	SU8686	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.44541888008836583	[213]	[241,202,410,322]	7	hSpCas9	negative selection	8949469
45971933	45971956	17	-	27260156	SU8686	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.012094221396150573	[207]	[208,130,316,181]	0	hSpCas9	negative selection	8949470
45996407	45996430	17	-	27260156	SU8686	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.5934951989112853	[368]	[608,470,623,496]	8	hSpCas9	negative selection	8949471
45974433	45974456	17	-	27260156	SU8686	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-0.2495736595330511	[10]	[1,0,1,37]	-4	hSpCas9	negative selection	9013727
45971920	45971943	17	+	27260156	SU8686	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.4705322820850285	[275]	[156,111,187,375]	-6	hSpCas9	negative selection	9013728
45974383	45974406	17	+	27260156	SU8686	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	-0.46225633712620084	[358]	[174,259,407,190]	-6	hSpCas9	negative selection	9013729
45996540	45996563	17	-	27260156	SKES1	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	0.014463869248328098	[213]	[286,197,223,164]	0	hSpCas9	negative selection	9070720
45971933	45971956	17	-	27260156	SKES1	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.10982328346063008	[207]	[174,258,195,256]	2	hSpCas9	negative selection	9070721
45996407	45996430	17	-	27260156	SKES1	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.6129984757052198	[368]	[775,479,468,543]	9	hSpCas9	negative selection	9070722
45974433	45974456	17	-	27260156	SKES1	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	0.795507447283657	[10]	[32,25,0,18]	9	hSpCas9	negative selection	9134978
45971920	45971943	17	+	27260156	SKES1	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.33023937390599	[275]	[297,153,216,208]	-6	hSpCas9	negative selection	9134979
45974383	45974406	17	+	27260156	SKES1	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.08179909415913478	[358]	[358,454,470,247]	1	hSpCas9	negative selection	9134980
45996540	45996563	17	-	27260156	TOV112D	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.07270607784668193	[213]	[242,173,268,126]	-1	hSpCas9	negative selection	9191971
45971933	45971956	17	-	27260156	TOV112D	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.03615912593179438	[207]	[286,334,121,147]	0	hSpCas9	negative selection	9191972
45996407	45996430	17	-	27260156	TOV112D	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.256662881078305	[368]	[372,459,410,517]	5	hSpCas9	negative selection	9191973
45974433	45974456	17	-	27260156	TOV112D	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-0.1791757430047971	[10]	[2,9,0,23]	-4	hSpCas9	negative selection	9256229
45971920	45971943	17	+	27260156	TOV112D	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.5678565381850905	[275]	[218,279,180,93]	-8	hSpCas9	negative selection	9256230
45974383	45974406	17	+	27260156	TOV112D	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.2593602741791733	[358]	[402,435,455,424]	5	hSpCas9	negative selection	9256231
45996540	45996563	17	-	27260156	TC71	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.16207051387712323	[213]	[207,201,194,215]	-4	hSpCas9	negative selection	9313222
45971933	45971956	17	-	27260156	TC71	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.31424887224764075	[207]	[281,190,317,318]	7	hSpCas9	negative selection	9313223
45996407	45996430	17	-	27260156	TC71	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.4727537512792361	[368]	[632,501,520,537]	9	hSpCas9	negative selection	9313224
45974433	45974456	17	-	27260156	TC71	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-0.16680624514967413	[10]	[4,18,9,7]	-4	hSpCas9	negative selection	9377480
45971920	45971943	17	+	27260156	TC71	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	-0.19080186256087162	[275]	[257,234,273,269]	-5	hSpCas9	negative selection	9377481
45974383	45974406	17	+	27260156	TC71	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	-0.007540271988129843	[358]	[275,401,417,439]	0	hSpCas9	negative selection	9377482
45996540	45996563	17	-	27260156	TC32	viability	CTTGGCGGAAGACGGCGACTTGG	MAPT	ENSG00000186868	-0.07216596507059547	[213]	[110,278,178,154]	-1	hSpCas9	negative selection	9434473
45971933	45971956	17	-	27260156	TC32	viability	GGGGGCCCACCTTCCGCTGTTGG	MAPT	ENSG00000186868	0.5072951561588297	[207]	[266,205,390,278]	8	hSpCas9	negative selection	9434474
45996407	45996430	17	-	27260156	TC32	viability	CCGCTGCGATCCCCTGATTTTGG	MAPT	ENSG00000186868	0.6351128319210353	[368]	[575,502,535,509]	9	hSpCas9	negative selection	9434475
45974433	45974456	17	-	27260156	TC32	viability	GATCTCCGTGTGGGGCTGCGCGG	MAPT	ENSG00000186868	-0.7055322418120413	[10]	[1,0,26,0]	-8	hSpCas9	negative selection	9498731
45971920	45971943	17	+	27260156	TC32	viability	TGCTAAGAGCACTCCAACAGCGG	MAPT	ENSG00000186868	0.024302514548984133	[275]	[313,214,226,288]	0	hSpCas9	negative selection	9498732
45974383	45974406	17	+	27260156	TC32	viability	AGATGTGACAGCACCCTTAGTGG	MAPT	ENSG00000186868	0.038146470127204735	[358]	[443,237,374,339]	0	hSpCas9	negative selection	9498733
45971882	45971905	17	+	27869803	HPAFII	viability after 27 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-0.624960568653075	[123]	[80,9,NaN]	-4	hSpCas9	negative selection	9561308
45972062	45972085	17	+	27869803	HPAFII	viability after 27 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	-0.06945530574669301	[220]	[221,17,NaN]	0	hSpCas9	negative selection	9561309
45978371	45978394	17	-	27869803	HPAFII	viability after 27 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	1.550640290122912	[170]	[180,331,NaN]	9	hSpCas9	negative selection	9561310
45983569	45983592	17	+	27869803	HPAFII	viability after 27 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-2.7564675648281725	[540]	[40,42,NaN]	-9	hSpCas9	negative selection	9561311
45990039	45990062	17	+	27869803	HPAFII	viability after 27 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	0.010636194103262095	[269]	[184,107,NaN]	0	hSpCas9	negative selection	9561312
45991522	45991545	17	-	27869803	HPAFII	viability after 27 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	0.26960315635632615	[69]	[63,27,NaN]	2	hSpCas9	negative selection	9561313
45971882	45971905	17	+	27869803	HPAFII	viability after 15 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-0.5189021557502169	[123]	[166,46,NaN]	-5	hSpCas9	negative selection	9643757
45972062	45972085	17	+	27869803	HPAFII	viability after 15 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	0.41163769462225674	[220]	[577,152,NaN]	5	hSpCas9	negative selection	9643758
45978371	45978394	17	-	27869803	HPAFII	viability after 15 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	1.316881588091047	[170]	[381,504,NaN]	9	hSpCas9	negative selection	9643759
45983569	45983592	17	+	27869803	HPAFII	viability after 15 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-1.8335741937145524	[540]	[135,179,NaN]	-9	hSpCas9	negative selection	9643760
45990039	45990062	17	+	27869803	HPAFII	viability after 15 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.0706040345980268	[269]	[464,158,NaN]	0	hSpCas9	negative selection	9643761
45991522	45991545	17	-	27869803	HPAFII	viability after 15 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	0.881036874784978	[69]	[169,118,NaN]	8	hSpCas9	negative selection	9643762
45971882	45971905	17	+	27869803	ASPC1	viability after 36 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-0.35254793248209015	[211]	[141,31,18]	-4	hSpCas9	negative selection	9726206
45972062	45972085	17	+	27869803	ASPC1	viability after 36 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	0.7677006721928767	[413]	[394,17,319]	7	hSpCas9	negative selection	9726207
45978371	45978394	17	-	27869803	ASPC1	viability after 36 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	0.5702521414543666	[356]	[269,167,136]	5	hSpCas9	negative selection	9726208
45983569	45983592	17	+	27869803	ASPC1	viability after 36 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-0.10373262943683681	[1613]	[488,485,573]	-1	hSpCas9	negative selection	9726209
45990039	45990062	17	+	27869803	ASPC1	viability after 36 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	0.2239370042167741	[784]	[314,444,220]	2	hSpCas9	negative selection	9726210
45991522	45991545	17	-	27869803	ASPC1	viability after 36 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	0.6866528839255829	[262]	[105,354,10]	6	hSpCas9	negative selection	9726211
45971882	45971905	17	+	27869803	PATU8988S	viability after 35 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	0.1799716211432023	[113]	[57,45,NaN]	2	hSpCas9	negative selection	9808655
45972062	45972085	17	+	27869803	PATU8988S	viability after 35 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	0.7852559568451822	[381]	[328,200,NaN]	8	hSpCas9	negative selection	9808656
45978371	45978394	17	-	27869803	PATU8988S	viability after 35 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	0.4258829470628254	[340]	[183,184,NaN]	5	hSpCas9	negative selection	9808657
45983569	45983592	17	+	27869803	PATU8988S	viability after 35 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-1.51389794881249	[1299]	[111,254,NaN]	-8	hSpCas9	negative selection	9808658
45990039	45990062	17	+	27869803	PATU8988S	viability after 35 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	0.16130611252232202	[744]	[354,315,NaN]	2	hSpCas9	negative selection	9808659
45991522	45991545	17	-	27869803	PATU8988S	viability after 35 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	-0.6302470958859012	[191]	[31,67,NaN]	-6	hSpCas9	negative selection	9808660
45971882	45971905	17	+	27869803	PATU8988S	viability after 31 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-0.13055592071657163	[113]	[59,17,NaN]	-1	hSpCas9	negative selection	9891104
45972062	45972085	17	+	27869803	PATU8988S	viability after 31 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	0.5213735121409324	[381]	[160,291,NaN]	6	hSpCas9	negative selection	9891105
45978371	45978394	17	-	27869803	PATU8988S	viability after 31 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	0.9188456385965544	[340]	[198,330,NaN]	8	hSpCas9	negative selection	9891106
45983569	45983592	17	+	27869803	PATU8988S	viability after 31 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-1.1012789544539778	[1299]	[106,412,NaN]	-8	hSpCas9	negative selection	9891107
45990039	45990062	17	+	27869803	PATU8988S	viability after 31 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.07127802775886988	[744]	[203,382,NaN]	-1	hSpCas9	negative selection	9891108
45991522	45991545	17	-	27869803	PATU8988S	viability after 31 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	-0.971751594371395	[191]	[20,61,NaN]	-7	hSpCas9	negative selection	9891109
45971882	45971905	17	+	27869803	HPAFII	viability after 35 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-4.599750235659697	[123]	[3,0,NaN]	-9	hSpCas9	negative selection	9973553
45972062	45972085	17	+	27869803	HPAFII	viability after 35 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	0.6604700548574145	[220]	[324,9,NaN]	4	hSpCas9	negative selection	9973554
45978371	45978394	17	-	27869803	HPAFII	viability after 35 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	1.7351111186397068	[170]	[76,525,NaN]	9	hSpCas9	negative selection	9973555
45983569	45983592	17	+	27869803	HPAFII	viability after 35 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-2.5613679099024997	[540]	[20,74,NaN]	-8	hSpCas9	negative selection	9973556
45990039	45990062	17	+	27869803	HPAFII	viability after 35 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	-0.03238755042039736	[269]	[143,121,NaN]	0	hSpCas9	negative selection	9973557
45991522	45991545	17	-	27869803	HPAFII	viability after 35 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	-0.3678059999322085	[69]	[10,45,NaN]	-2	hSpCas9	negative selection	9973558
45971882	45971905	17	+	27869803	HPAFII	viability after 31 days	GAGGACGGATCTGAGGAACCGGG	MAPT	ENSG00000186868	-0.765536946740778	[123]	[72,5,NaN]	-5	hSpCas9	negative selection	10056002
45972062	45972085	17	+	27869803	HPAFII	viability after 31 days	CGGTGCTTTGCAGGACAGCGTGG	MAPT	ENSG00000186868	0.12388634193115841	[220]	[238,21,NaN]	0	hSpCas9	negative selection	10056003
45978371	45978394	17	-	27869803	HPAFII	viability after 31 days	CCAATGCCTGCTTCTTCAGCTGG	MAPT	ENSG00000186868	1.7245727087687164	[170]	[141,507,NaN]	9	hSpCas9	negative selection	10056004
45983569	45983592	17	+	27869803	HPAFII	viability after 31 days	CATCCCAGGCTTCCCAGCGGAGG	MAPT	ENSG00000186868	-3.598963568651791	[540]	[3,47,NaN]	-9	hSpCas9	negative selection	10056005
45990039	45990062	17	+	27869803	HPAFII	viability after 31 days	AACTGGCAGTTCTGGAGCAAAGG	MAPT	ENSG00000186868	0.17651578047231603	[269]	[187,152,NaN]	1	hSpCas9	negative selection	10056006
45991522	45991545	17	-	27869803	HPAFII	viability after 31 days	GAATCCTGGTGGCGTTGGCCTGG	MAPT	ENSG00000186868	0.13346503281183275	[69]	[33,52,NaN]	0	hSpCas9	negative selection	10056007
45962362	45962385	17	+	28162770	P31FUJ	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	0.005709882285346302	[88]	[104]	0	hSpCas9	negative selection	10189251
45996631	45996654	17	+	28162770	P31FUJ	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	0.22126622945582586	[391]	[536]	2	hSpCas9	negative selection	10189252
45978419	45978442	17	+	28162770	P31FUJ	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.5877281063909586	[217]	[384]	6	hSpCas9	negative selection	10189253
45962349	45962372	17	-	28162770	P31FUJ	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	0.11172731941011627	[303]	[385]	1	hSpCas9	negative selection	10189254
45962440	45962463	17	+	28162770	P31FUJ	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	1.188335494400883	[176]	[473]	9	hSpCas9	negative selection	10189255
45991473	45991496	17	+	28162770	P31FUJ	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.2322234306961417	[233]	[322]	2	hSpCas9	negative selection	10189256
45996397	45996420	17	+	28162770	P31FUJ	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	0.012577039293466097	[506]	[600]	0	hSpCas9	negative selection	10189257
45996407	45996430	17	+	28162770	P31FUJ	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	0.15567708338158986	[232]	[304]	1	hSpCas9	negative selection	10189258
45996477	45996500	17	-	28162770	P31FUJ	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-1.7618559639848783	[328]	[113]	-8	hSpCas9	negative selection	10189259
45996505	45996528	17	+	28162770	P31FUJ	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-2.390804038480872	[240]	[53]	-8	hSpCas9	negative selection	10189260
45962362	45962385	17	+	28162770	TF1	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	NaN	[NaN]	[142]	1	hSpCas9	negative selection	10358617
45996631	45996654	17	+	28162770	TF1	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	NaN	[NaN]	[543]	1	hSpCas9	negative selection	10358618
45978419	45978442	17	+	28162770	TF1	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	NaN	[NaN]	[229]	1	hSpCas9	negative selection	10358619
45962349	45962372	17	-	28162770	TF1	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	NaN	[NaN]	[182]	1	hSpCas9	negative selection	10358620
45962440	45962463	17	+	28162770	TF1	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	NaN	[NaN]	[222]	1	hSpCas9	negative selection	10358621
45991473	45991496	17	+	28162770	TF1	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	NaN	[NaN]	[273]	1	hSpCas9	negative selection	10358622
45996397	45996420	17	+	28162770	TF1	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	NaN	[NaN]	[476]	1	hSpCas9	negative selection	10358623
45996407	45996430	17	+	28162770	TF1	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10358624
45996477	45996500	17	-	28162770	TF1	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10358625
45996505	45996528	17	+	28162770	TF1	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10358626
45962362	45962385	17	+	28162770	SKM1	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	0.37064337992039054	[27]	[63]	3	hSpCas9	negative selection	10527983
45996631	45996654	17	+	28162770	SKM1	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	-0.34200875690239185	[75]	[105]	-3	hSpCas9	negative selection	10527984
45978419	45978442	17	+	28162770	SKM1	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	1.114183204380551	[51]	[198]	9	hSpCas9	negative selection	10527985
45962349	45962372	17	-	28162770	SKM1	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	0.14003045177897394	[76]	[149]	1	hSpCas9	negative selection	10527986
45962440	45962463	17	+	28162770	SKM1	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	0.8267367131324653	[58]	[184]	7	hSpCas9	negative selection	10527987
45991473	45991496	17	+	28162770	SKM1	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.28142789163340004	[73]	[158]	2	hSpCas9	negative selection	10527988
45996397	45996420	17	+	28162770	SKM1	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	1.1275332349950067	[79]	[308]	9	hSpCas9	negative selection	10527989
45996407	45996430	17	+	28162770	SKM1	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	-0.6672791032233635	[52]	[58]	-5	hSpCas9	negative selection	10527990
45996477	45996500	17	-	28162770	SKM1	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-1.076574525107603	[67]	[56]	-7	hSpCas9	negative selection	10527991
45996505	45996528	17	+	28162770	SKM1	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-1.0335058032157172	[65]	[56]	-6	hSpCas9	negative selection	10527992
45962362	45962385	17	+	28162770	SKM1	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	0.37064337992039054	[27]	[63]	3	hSpCas9	negative selection	10697349
45996631	45996654	17	+	28162770	SKM1	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	-0.34200875690239185	[75]	[105]	-3	hSpCas9	negative selection	10697350
45978419	45978442	17	+	28162770	SKM1	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	1.114183204380551	[51]	[198]	9	hSpCas9	negative selection	10697351
45962349	45962372	17	-	28162770	SKM1	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	0.14003045177897394	[76]	[149]	1	hSpCas9	negative selection	10697352
45962440	45962463	17	+	28162770	SKM1	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	0.8267367131324653	[58]	[184]	7	hSpCas9	negative selection	10697353
45991473	45991496	17	+	28162770	SKM1	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.28142789163340004	[73]	[158]	2	hSpCas9	negative selection	10697354
45996397	45996420	17	+	28162770	SKM1	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	1.1275332349950067	[79]	[308]	9	hSpCas9	negative selection	10697355
45996407	45996430	17	+	28162770	SKM1	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	-0.6672791032233635	[52]	[58]	-5	hSpCas9	negative selection	10697356
45996477	45996500	17	-	28162770	SKM1	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-1.076574525107603	[67]	[56]	-7	hSpCas9	negative selection	10697357
45996505	45996528	17	+	28162770	SKM1	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-1.0335058032157172	[65]	[56]	-6	hSpCas9	negative selection	10697358
45962362	45962385	17	+	28162770	PL21	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	-1.384822886231836	[83]	[13]	-7	hSpCas9	negative selection	10866715
45996631	45996654	17	+	28162770	PL21	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	-0.4991063137277273	[301]	[92]	-4	hSpCas9	negative selection	10866716
45978419	45978442	17	+	28162770	PL21	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	-0.5194089265994767	[246]	[74]	-4	hSpCas9	negative selection	10866717
45962349	45962372	17	-	28162770	PL21	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	0.08149511799070108	[303]	[139]	0	hSpCas9	negative selection	10866718
45962440	45962463	17	+	28162770	PL21	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	1.3167845333415908	[189]	[205]	9	hSpCas9	negative selection	10866719
45991473	45991496	17	+	28162770	PL21	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	-0.44662817070530775	[309]	[98]	-3	hSpCas9	negative selection	10866720
45996397	45996420	17	+	28162770	PL21	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	0.15831943879469312	[349]	[169]	1	hSpCas9	negative selection	10866721
45996407	45996430	17	+	28162770	PL21	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	0.22031749642695045	[141]	[71]	2	hSpCas9	negative selection	10866722
45996477	45996500	17	-	28162770	PL21	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-1.4007644301008577	[181]	[29]	-7	hSpCas9	negative selection	10866723
45996505	45996528	17	+	28162770	PL21	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	0.39471214100283036	[186]	[106]	3	hSpCas9	negative selection	10866724
45962362	45962385	17	+	28162770	P31FUJ	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	0.005709882285346302	[88]	[104]	0	hSpCas9	negative selection	11036081
45996631	45996654	17	+	28162770	P31FUJ	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	0.22126622945582586	[391]	[536]	2	hSpCas9	negative selection	11036082
45978419	45978442	17	+	28162770	P31FUJ	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.5877281063909586	[217]	[384]	6	hSpCas9	negative selection	11036083
45962349	45962372	17	-	28162770	P31FUJ	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	0.11172731941011627	[303]	[385]	1	hSpCas9	negative selection	11036084
45962440	45962463	17	+	28162770	P31FUJ	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	1.188335494400883	[176]	[473]	9	hSpCas9	negative selection	11036085
45991473	45991496	17	+	28162770	P31FUJ	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.2322234306961417	[233]	[322]	2	hSpCas9	negative selection	11036086
45996397	45996420	17	+	28162770	P31FUJ	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	0.012577039293466097	[506]	[600]	0	hSpCas9	negative selection	11036087
45996407	45996430	17	+	28162770	P31FUJ	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	0.15567708338158986	[232]	[304]	1	hSpCas9	negative selection	11036088
45996477	45996500	17	-	28162770	P31FUJ	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-1.7618559639848783	[328]	[113]	-8	hSpCas9	negative selection	11036089
45996505	45996528	17	+	28162770	P31FUJ	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-2.390804038480872	[240]	[53]	-8	hSpCas9	negative selection	11036090
45962362	45962385	17	+	28162770	OCIAML5	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	-1.0484637836675006	[54]	[47]	-6	hSpCas9	negative selection	11205447
45996631	45996654	17	+	28162770	OCIAML5	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	0.4989544355436919	[215]	[550]	4	hSpCas9	negative selection	11205448
45978419	45978442	17	+	28162770	OCIAML5	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	1.0130038490498947	[83]	[305]	8	hSpCas9	negative selection	11205449
45962349	45962372	17	-	28162770	OCIAML5	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	-0.3845000204442008	[208]	[288]	-3	hSpCas9	negative selection	11205450
45962440	45962463	17	+	28162770	OCIAML5	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	0.5927182718088988	[107]	[293]	5	hSpCas9	negative selection	11205451
45991473	45991496	17	+	28162770	OCIAML5	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	1.2572808253243637	[126]	[547]	9	hSpCas9	negative selection	11205452
45996397	45996420	17	+	28162770	OCIAML5	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	0.14793342913600305	[299]	[599]	1	hSpCas9	negative selection	11205453
45996407	45996430	17	+	28162770	OCIAML5	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	0.05427432192175785	[174]	[327]	0	hSpCas9	negative selection	11205454
45996477	45996500	17	-	28162770	OCIAML5	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-2.2506159473542717	[144]	[54]	-8	hSpCas9	negative selection	11205455
45996505	45996528	17	+	28162770	OCIAML5	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-2.3912253819720286	[185]	[63]	-8	hSpCas9	negative selection	11205456
45962362	45962385	17	+	28162770	EOL1	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	-2.335319355184576	[181]	[18]	-8	hSpCas9	negative selection	11374813
45996631	45996654	17	+	28162770	EOL1	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	-0.5748966579645644	[392]	[138]	-4	hSpCas9	negative selection	11374814
45978419	45978442	17	+	28162770	EOL1	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.9356883291757347	[386]	[389]	7	hSpCas9	negative selection	11374815
45962349	45962372	17	-	28162770	EOL1	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	-0.2032077756278381	[530]	[242]	-1	hSpCas9	negative selection	11374816
45962440	45962463	17	+	28162770	EOL1	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	0.8154549143486527	[356]	[330]	7	hSpCas9	negative selection	11374817
45991473	45991496	17	+	28162770	EOL1	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.47561439994785215	[444]	[325]	4	hSpCas9	negative selection	11374818
45996397	45996420	17	+	28162770	EOL1	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	0.6503728081315403	[415]	[343]	6	hSpCas9	negative selection	11374819
45996407	45996430	17	+	28162770	EOL1	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	1.055792304848787	[209]	[229]	8	hSpCas9	negative selection	11374820
45996477	45996500	17	-	28162770	EOL1	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-1.9438082226189946	[313]	[42]	-8	hSpCas9	negative selection	11374821
45996505	45996528	17	+	28162770	EOL1	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-1.778734696339383	[253]	[38]	-8	hSpCas9	negative selection	11374822
45962362	45962385	17	+	28162770	MOLM13	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	-0.33946554051302535	[132]	[75]	-2	hSpCas9	negative selection	11544179
45996631	45996654	17	+	28162770	MOLM13	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	-0.4525718534702144	[493]	[260]	-3	hSpCas9	negative selection	11544180
45978419	45978442	17	+	28162770	MOLM13	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	1.1421192203628223	[281]	[449]	8	hSpCas9	negative selection	11544181
45962349	45962372	17	-	28162770	MOLM13	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	-0.6330050818792211	[606]	[282]	-4	hSpCas9	negative selection	11544182
45962440	45962463	17	+	28162770	MOLM13	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	1.5967444472210028	[288]	[631]	9	hSpCas9	negative selection	11544183
45991473	45991496	17	+	28162770	MOLM13	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	1.0391336010179546	[316]	[470]	7	hSpCas9	negative selection	11544184
45996397	45996420	17	+	28162770	MOLM13	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	-0.2617837200552714	[591]	[356]	-2	hSpCas9	negative selection	11544185
45996407	45996430	17	+	28162770	MOLM13	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	1.3583758967980883	[170]	[316]	9	hSpCas9	negative selection	11544186
45996477	45996500	17	-	28162770	MOLM13	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-3.111336749627433	[250]	[20]	-8	hSpCas9	negative selection	11544187
45996505	45996528	17	+	28162770	MOLM13	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-2.6139047096190686	[253]	[29]	-8	hSpCas9	negative selection	11544188
45962362	45962385	17	+	28162770	HEL	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	-0.9666767124453384	[118]	[38]	-5	hSpCas9	negative selection	11713545
45996631	45996654	17	+	28162770	HEL	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	-0.20832274918742455	[376]	[208]	-1	hSpCas9	negative selection	11713546
45978419	45978442	17	+	28162770	HEL	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	1.1537007512777362	[239]	[341]	8	hSpCas9	negative selection	11713547
45962349	45962372	17	-	28162770	HEL	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	0.06466271686444058	[417]	[279]	0	hSpCas9	negative selection	11713548
45962440	45962463	17	+	28162770	HEL	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	1.012610015231066	[218]	[282]	8	hSpCas9	negative selection	11713549
45991473	45991496	17	+	28162770	HEL	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.6427388320003571	[313]	[313]	5	hSpCas9	negative selection	11713550
45996397	45996420	17	+	28162770	HEL	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	0.08484457447737148	[395]	[268]	0	hSpCas9	negative selection	11713551
45996407	45996430	17	+	28162770	HEL	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	0.6911018535617558	[175]	[181]	6	hSpCas9	negative selection	11713552
45996477	45996500	17	-	28162770	HEL	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-3.2572653780229217	[208]	[13]	-9	hSpCas9	negative selection	11713553
45996505	45996528	17	+	28162770	HEL	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-1.611017760245426	[185]	[38]	-7	hSpCas9	negative selection	11713554
45962362	45962385	17	+	28162770	MV411	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	-0.5092912982048609	[97]	[57]	-4	hSpCas9	negative selection	11882911
45996631	45996654	17	+	28162770	MV411	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	0.9509445032716837	[252]	[411]	8	hSpCas9	negative selection	11882912
45978419	45978442	17	+	28162770	MV411	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.9503413088753485	[179]	[292]	8	hSpCas9	negative selection	11882913
45962349	45962372	17	-	28162770	MV411	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	0.23195230328535665	[280]	[277]	2	hSpCas9	negative selection	11882914
45962440	45962463	17	+	28162770	MV411	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	0.6680132336030492	[194]	[260]	6	hSpCas9	negative selection	11882915
45991473	45991496	17	+	28162770	MV411	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.274007271186678	[268]	[273]	2	hSpCas9	negative selection	11882916
45996397	45996420	17	+	28162770	MV411	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	0.6838775267938433	[367]	[497]	6	hSpCas9	negative selection	11882917
45996407	45996430	17	+	28162770	MV411	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	0.6691387803426297	[161]	[216]	6	hSpCas9	negative selection	11882918
45996477	45996500	17	-	28162770	MV411	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-1.312967845694402	[232]	[78]	-7	hSpCas9	negative selection	11882919
45996505	45996528	17	+	28162770	MV411	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-1.2871514274232616	[196]	[67]	-7	hSpCas9	negative selection	11882920
45962362	45962385	17	+	28162770	MONOMAC1	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	1.3784653244125362	[50]	[151]	9	hSpCas9	negative selection	12052277
45996631	45996654	17	+	28162770	MONOMAC1	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	-0.0827796678018739	[181]	[196]	0	hSpCas9	negative selection	12052278
45978419	45978442	17	+	28162770	MONOMAC1	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	-0.08600553467080989	[124]	[134]	0	hSpCas9	negative selection	12052279
45962349	45962372	17	-	28162770	MONOMAC1	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	-0.3421535549193637	[208]	[188]	-3	hSpCas9	negative selection	12052280
45962440	45962463	17	+	28162770	MONOMAC1	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	0.201047518938093	[106]	[140]	2	hSpCas9	negative selection	12052281
45991473	45991496	17	+	28162770	MONOMAC1	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	0.36407891170723483	[182]	[269]	3	hSpCas9	negative selection	12052282
45996397	45996420	17	+	28162770	MONOMAC1	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	0.2232183614903095	[206]	[276]	2	hSpCas9	negative selection	12052283
45996407	45996430	17	+	28162770	MONOMAC1	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	0.17421896019137703	[91]	[118]	1	hSpCas9	negative selection	12052284
45996477	45996500	17	-	28162770	MONOMAC1	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-0.46712601042729796	[163]	[135]	-4	hSpCas9	negative selection	12052285
45996505	45996528	17	+	28162770	MONOMAC1	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	0.36343109174085375	[98]	[145]	3	hSpCas9	negative selection	12052286
45962362	45962385	17	+	28162770	OCIAML2	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	-1.3186267317971112	[26]	[59]	-7	hSpCas9	negative selection	12221643
45996631	45996654	17	+	28162770	OCIAML2	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	0.326025208158234	[57]	[402]	3	hSpCas9	negative selection	12221644
45978419	45978442	17	+	28162770	OCIAML2	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	0.8602870528724559	[31]	[321]	8	hSpCas9	negative selection	12221645
45962349	45962372	17	-	28162770	OCIAML2	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	0.03460548300826094	[61]	[351]	0	hSpCas9	negative selection	12221646
45962440	45962463	17	+	28162770	OCIAML2	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	0.9956881789803759	[37]	[419]	8	hSpCas9	negative selection	12221647
45991473	45991496	17	+	28162770	OCIAML2	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	-0.47062982524216135	[73]	[295]	-4	hSpCas9	negative selection	12221648
45996397	45996420	17	+	28162770	OCIAML2	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	0.8399384074806535	[50]	[505]	7	hSpCas9	negative selection	12221649
45996407	45996430	17	+	28162770	OCIAML2	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	-0.2947799898427436	[26]	[121]	-2	hSpCas9	negative selection	12221650
45996477	45996500	17	-	28162770	OCIAML2	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-2.0555923259633175	[38]	[51]	-8	hSpCas9	negative selection	12221651
45996505	45996528	17	+	28162770	OCIAML2	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-2.055592325963317	[35]	[47]	-8	hSpCas9	negative selection	12221652
45962362	45962385	17	+	28162770	OCIAML3	viability	GAAGTGATGGAAGATCACGCTGG	MAPT	ENSG00000186868	-0.2561380015677792	[35]	[90]	-2	hSpCas9	negative selection	12391009
45996631	45996654	17	+	28162770	OCIAML3	viability	TGAGAACCTGAAGCACCAGCCGG	MAPT	ENSG00000186868	1.1649842601720422	[64]	[439]	8	hSpCas9	negative selection	12391010
45978419	45978442	17	+	28162770	OCIAML3	viability	GCTGCTGGTCACGTGACCCAAGG	MAPT	ENSG00000186868	-0.0009172587196066007	[58]	[177]	0	hSpCas9	negative selection	12391011
45962349	45962372	17	-	28162770	OCIAML3	viability	CCATCACTTCGAACTCCTGGCGG	MAPT	ENSG00000186868	-0.7980215323457565	[90]	[157]	-5	hSpCas9	negative selection	12391012
45962440	45962463	17	+	28162770	OCIAML3	viability	CAAGAGGGTGACACGGACGCTGG	MAPT	ENSG00000186868	-0.12743984040523734	[54]	[151]	-1	hSpCas9	negative selection	12391013
45991473	45991496	17	+	28162770	OCIAML3	viability	AAACGAAGATCGCCACACCGCGG	MAPT	ENSG00000186868	-0.08304572104678398	[79]	[227]	0	hSpCas9	negative selection	12391014
45996397	45996420	17	+	28162770	OCIAML3	viability	AGGTGAACCTCCAAAATCAGGGG	MAPT	ENSG00000186868	0.045245015897946494	[112]	[351]	0	hSpCas9	negative selection	12391015
45996407	45996430	17	+	28162770	OCIAML3	viability	CCAAAATCAGGGGATCGCAGCGG	MAPT	ENSG00000186868	-0.04007203522363145	[46]	[137]	0	hSpCas9	negative selection	12391016
45996477	45996500	17	-	28162770	OCIAML3	viability	GGGTGGGGTTGGAAGGGACGGGG	MAPT	ENSG00000186868	-0.5940076403241632	[54]	[109]	-4	hSpCas9	negative selection	12391017
45996505	45996528	17	+	28162770	OCIAML3	viability	GGAGCCCAAGAAGGTGGCAGTGG	MAPT	ENSG00000186868	-0.8411005022889355	[53]	[90]	-6	hSpCas9	negative selection	12391018