Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 57192
• Symbol: MCOLN1
• Description: mucolipin TRP cation channel 1

DataSource: http://genomecrispr.dkfz.de/#!/results/MCOLN1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
7526494	7526517	19	-	26472758	Jiyoye	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	0.06140054466414324	[60]	[47]	0	hSpCas9	negative selection	97763
7528642	7528665	19	-	26472758	Jiyoye	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-1.0078621177729707	[7]	[2]	-6	hSpCas9	negative selection	97764
7525133	7525156	19	+	26472758	Jiyoye	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-0.9913739949844014	[231]	[87]	-6	hSpCas9	negative selection	97765
7528661	7528684	19	-	26472758	Jiyoye	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-0.7448277119391766	[199]	[89]	-5	hSpCas9	negative selection	97766
7528949	7528972	19	+	26472758	Jiyoye	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.6912714028674969	[169]	[206]	5	hSpCas9	negative selection	97767
7529130	7529153	19	-	26472758	Jiyoye	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	0.07275634243531437	[28]	[22]	0	hSpCas9	negative selection	97768
7522744	7522767	19	+	26472758	Jiyoye	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	0.10761509964696558	[191]	[155]	0	hSpCas9	negative selection	97769
7524986	7525009	19	-	26472758	Jiyoye	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	-0.07315357802468958	[225]	[161]	0	hSpCas9	negative selection	97770
7525049	7525072	19	-	26472758	Jiyoye	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	0.7092039189555309	[72]	[89]	5	hSpCas9	negative selection	97771
7527560	7527583	19	-	26472758	Jiyoye	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	-0.4859094145776147	[259]	[139]	-3	hSpCas9	negative selection	97772
7526494	7526517	19	-	26472758	KBM7	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	1.097574845366091	[342,217]	[339,220]	9	hSpCas9	negative selection	288881
7528642	7528665	19	-	26472758	KBM7	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-4.25570262641387	[51,30]	[0,0]	-9	hSpCas9	negative selection	288882
7525133	7525156	19	+	26472758	KBM7	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-0.31013827317865084	[643,597]	[211,256]	-3	hSpCas9	negative selection	288883
7528661	7528684	19	-	26472758	KBM7	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-3.696249368660101	[845,430]	[12,30]	-9	hSpCas9	negative selection	288884
7528949	7528972	19	+	26472758	KBM7	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.41909441135991765	[746,500]	[493,289]	4	hSpCas9	negative selection	288885
7529130	7529153	19	-	26472758	KBM7	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	0.42318991559963426	[277,177]	[221,68]	4	hSpCas9	negative selection	288886
7522744	7522767	19	+	26472758	KBM7	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	0.860406932439994	[780,606]	[526,641]	8	hSpCas9	negative selection	288887
7524986	7525009	19	-	26472758	KBM7	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	-0.1515086189806768	[741,423]	[172,301]	-1	hSpCas9	negative selection	288888
7525049	7525072	19	-	26472758	KBM7	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	0.22499655994846346	[504,451]	[276,249]	2	hSpCas9	negative selection	288889
7527560	7527583	19	-	26472758	KBM7	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	0.4321147916082242	[774,805]	[411,587]	4	hSpCas9	negative selection	288890
7526494	7526517	19	-	26472758	Raji	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	1.43600628283497	[85]	[53]	9	hSpCas9	negative selection	479999
7528642	7528665	19	-	26472758	Raji	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-3.4472053163040384	[46]	[0]	-9	hSpCas9	negative selection	480000
7525133	7525156	19	+	26472758	Raji	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-1.107629355597251	[259]	[27]	-7	hSpCas9	negative selection	480001
7528661	7528684	19	-	26472758	Raji	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-2.161483315762349	[346]	[17]	-8	hSpCas9	negative selection	480002
7528949	7528972	19	+	26472758	Raji	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.45712957440072416	[225]	[71]	4	hSpCas9	negative selection	480003
7529130	7529153	19	-	26472758	Raji	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	-0.842575782126805	[84]	[10]	-6	hSpCas9	negative selection	480004
7522744	7522767	19	+	26472758	Raji	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	-0.11968537317232164	[411]	[87]	-1	hSpCas9	negative selection	480005
7524986	7525009	19	-	26472758	Raji	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	-0.10855386382554921	[445]	[95]	-1	hSpCas9	negative selection	480006
7525049	7525072	19	-	26472758	Raji	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	-0.05951377337114478	[237]	[52]	0	hSpCas9	negative selection	480007
7527560	7527583	19	-	26472758	Raji	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	0.5303262327377897	[363]	[121]	5	hSpCas9	negative selection	480008
7526494	7526517	19	-	26472758	K562	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	0.6455840523637333	[208]	[275]	5	hSpCas9	negative selection	671117
7528642	7528665	19	-	26472758	K562	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-2.5629361943911575	[62]	[8]	-8	hSpCas9	negative selection	671118
7525133	7525156	19	+	26472758	K562	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-1.8803542373834903	[518]	[118]	-7	hSpCas9	negative selection	671119
7528661	7528684	19	-	26472758	K562	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-1.72136555699564	[499]	[127]	-7	hSpCas9	negative selection	671120
7528949	7528972	19	+	26472758	K562	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.8773866012984353	[531]	[824]	7	hSpCas9	negative selection	671121
7529130	7529153	19	-	26472758	K562	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	-0.05307514891071974	[160]	[130]	0	hSpCas9	negative selection	671122
7522744	7522767	19	+	26472758	K562	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	0.9963037416683918	[480]	[809]	8	hSpCas9	negative selection	671123
7524986	7525009	19	-	26472758	K562	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	0.6660589617695378	[326]	[437]	5	hSpCas9	negative selection	671124
7525049	7525072	19	-	26472758	K562	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	0.8912204822054658	[273]	[428]	7	hSpCas9	negative selection	671125
7527560	7527583	19	-	26472758	K562	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	0.16044768733219938	[618]	[583]	1	hSpCas9	negative selection	671126
7525085	7525108	19	+	26627737	DLD1	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.10068276599262771	[1271]	[675,371,254]	1	hSpCas9	negative selection	807587
7526494	7526517	19	-	26627737	DLD1	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-0.5429099882081374	[238]	[36,103,19]	-5	hSpCas9	negative selection	807588
7526883	7526906	19	-	26627737	DLD1	viability	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	0.3352848452746885	[424]	[123,341,60]	3	hSpCas9	negative selection	807589
7527888	7527911	19	-	26627737	DLD1	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.38975923290958026	[65]	[37,17,24]	4	hSpCas9	negative selection	807590
7528240	7528263	19	-	26627737	DLD1	viability	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	-0.04688174765319286	[788]	[225,316,184]	0	hSpCas9	negative selection	807591
7528610	7528633	19	-	26627737	DLD1	viability	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.6514769624056158	[505]	[268,119,336]	6	hSpCas9	negative selection	807592
7525085	7525108	19	+	26627737	GBM cells	viability after 5 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.3758357470286875	[558]	[429,347]	6	hSpCas9	negative selection	889902
7526494	7526517	19	-	26627737	GBM cells	viability after 5 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	0.07341160611782183	[139]	[93,63]	1	hSpCas9	negative selection	889903
7526883	7526906	19	-	26627737	GBM cells	viability after 5 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	0.5484166278015525	[152]	[104,134]	7	hSpCas9	negative selection	889904
7527888	7527911	19	-	26627737	GBM cells	viability after 5 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.2693576077041129	[108]	[57,38]	-4	hSpCas9	negative selection	889905
7528240	7528263	19	-	26627737	GBM cells	viability after 5 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	-0.11641777887030502	[472]	[258,208]	-2	hSpCas9	negative selection	889906
7528610	7528633	19	-	26627737	GBM cells	viability after 5 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.2974632513759604	[351]	[215,247]	4	hSpCas9	negative selection	889907
7525085	7525108	19	+	26627737	GBM cells	viability after 13 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.6865054837645992	[558]	[534,449]	8	hSpCas9	negative selection	972217
7526494	7526517	19	-	26627737	GBM cells	viability after 13 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-1.559855675015685	[139]	[38,14]	-9	hSpCas9	negative selection	972218
7526883	7526906	19	-	26627737	GBM cells	viability after 13 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	1.456301963312387	[152]	[229,225]	9	hSpCas9	negative selection	972219
7527888	7527911	19	-	26627737	GBM cells	viability after 13 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.022805906401393683	[108]	[71,46]	0	hSpCas9	negative selection	972220
7528240	7528263	19	-	26627737	GBM cells	viability after 13 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	-0.5535343292332928	[472]	[170,177]	-6	hSpCas9	negative selection	972221
7528610	7528633	19	-	26627737	GBM cells	viability after 13 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	-0.02330401182751629	[351]	[177,195]	0	hSpCas9	negative selection	972222
7525085	7525108	19	+	26627737	GBM cells	viability after 21 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.9171225995433958	[558]	[620,529]	8	hSpCas9	negative selection	1054532
7526494	7526517	19	-	26627737	GBM cells	viability after 21 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-1.7867065032721077	[139]	[20,22]	-8	hSpCas9	negative selection	1054533
7526883	7526906	19	-	26627737	GBM cells	viability after 21 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	1.2634920902218414	[152]	[209,189]	9	hSpCas9	negative selection	1054534
7527888	7527911	19	-	26627737	GBM cells	viability after 21 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.3546645592124342	[108]	[38,52]	-3	hSpCas9	negative selection	1054535
7528240	7528263	19	-	26627737	GBM cells	viability after 21 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	-0.17820859422842772	[472]	[247,207]	-2	hSpCas9	negative selection	1054536
7528610	7528633	19	-	26627737	GBM cells	viability after 21 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.30710794443078726	[351]	[245,227]	3	hSpCas9	negative selection	1054537
7525085	7525108	19	+	26627737	RPE1	viability after 9 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	2.1325543719884332	[933]	[1341,1204]	9	hSpCas9	negative selection	1136847
7526494	7526517	19	-	26627737	RPE1	viability after 9 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	2.7888618911294247	[43]	[68,128]	9	hSpCas9	negative selection	1136848
7526883	7526906	19	-	26627737	RPE1	viability after 9 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	-0.6095013270703766	[938]	[155,239]	-4	hSpCas9	negative selection	1136849
7527888	7527911	19	-	26627737	RPE1	viability after 9 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-2.827410339325504	[341]	[25,0]	-9	hSpCas9	negative selection	1136850
7528240	7528263	19	-	26627737	RPE1	viability after 9 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	-0.4039860297699326	[1607]	[238,562]	-3	hSpCas9	negative selection	1136851
7528610	7528633	19	-	26627737	RPE1	viability after 9 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.2428897653344178	[1099]	[448,353]	1	hSpCas9	negative selection	1136852
7525085	7525108	19	+	26627737	RPE1	viability after 12 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	1.9100777609049944	[933]	[1047,831]	8	hSpCas9	negative selection	1219162
7526494	7526517	19	-	26627737	RPE1	viability after 12 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	2.888597358015831	[43]	[88,85]	9	hSpCas9	negative selection	1219163
7526883	7526906	19	-	26627737	RPE1	viability after 12 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	-0.9161684395652925	[938]	[122,144]	-6	hSpCas9	negative selection	1219164
7527888	7527911	19	-	26627737	RPE1	viability after 12 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-4.233171605271829	[341]	[0,8]	-9	hSpCas9	negative selection	1219165
7528240	7528263	19	-	26627737	RPE1	viability after 12 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	-0.07385249626702939	[1607]	[391,429]	0	hSpCas9	negative selection	1219166
7528610	7528633	19	-	26627737	RPE1	viability after 12 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	-0.2779602654991181	[1099]	[268,216]	-2	hSpCas9	negative selection	1219167
7525085	7525108	19	+	26627737	RPE1	viability after 15 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	1.872250579754744	[933]	[979,954]	8	hSpCas9	negative selection	1301477
7526494	7526517	19	-	26627737	RPE1	viability after 15 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	1.6260484961540245	[43]	[42,33]	8	hSpCas9	negative selection	1301478
7526883	7526906	19	-	26627737	RPE1	viability after 15 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	-0.5341477404790904	[938]	[102,260]	-3	hSpCas9	negative selection	1301479
7527888	7527911	19	-	26627737	RPE1	viability after 15 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-3.3717308555493153	[341]	[17,0]	-9	hSpCas9	negative selection	1301480
7528240	7528263	19	-	26627737	RPE1	viability after 15 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	-0.4598090943030214	[1607]	[317,342]	-3	hSpCas9	negative selection	1301481
7528610	7528633	19	-	26627737	RPE1	viability after 15 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.6202767207920532	[1099]	[544,413]	4	hSpCas9	negative selection	1301482
7525085	7525108	19	+	26627737	RPE1	viability after 18 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	1.8981206773982295	[933]	[1113,752]	8	hSpCas9	negative selection	1383792
7526494	7526517	19	-	26627737	RPE1	viability after 18 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	2.166774833748022	[43]	[47,58]	9	hSpCas9	negative selection	1383793
7526883	7526906	19	-	26627737	RPE1	viability after 18 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	-0.9879864290156226	[938]	[149,103]	-6	hSpCas9	negative selection	1383794
7527888	7527911	19	-	26627737	RPE1	viability after 18 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-3.6308979412337337	[341]	[5,8]	-9	hSpCas9	negative selection	1383795
7528240	7528263	19	-	26627737	RPE1	viability after 18 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	-0.44575092960507534	[1607]	[277,361]	-3	hSpCas9	negative selection	1383796
7528610	7528633	19	-	26627737	RPE1	viability after 18 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.2163572785106062	[1099]	[326,363]	1	hSpCas9	negative selection	1383797
7525085	7525108	19	+	26627737	HeLa	viability after 8 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.6940417151124414	[834]	[746,278,759]	6	hSpCas9	negative selection	1466107
7526494	7526517	19	-	26627737	HeLa	viability after 8 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	1.6376326624591662	[138]	[120,287,143]	9	hSpCas9	negative selection	1466108
7526883	7526906	19	-	26627737	HeLa	viability after 8 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	0.8345206589150312	[275]	[314,154,195]	7	hSpCas9	negative selection	1466109
7527888	7527911	19	-	26627737	HeLa	viability after 8 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	1.0272533740018566	[101]	[97,83,90]	7	hSpCas9	negative selection	1466110
7528240	7528263	19	-	26627737	HeLa	viability after 8 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	-0.0698282285696995	[562]	[198,309,186]	0	hSpCas9	negative selection	1466111
7528610	7528633	19	-	26627737	HeLa	viability after 8 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.49888757762256575	[477]	[336,315,241]	4	hSpCas9	negative selection	1466112
7525085	7525108	19	+	26627737	HeLa	viability after 12 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.4595020967459811	[834]	[583,414,433]	4	hSpCas9	negative selection	1548422
7526494	7526517	19	-	26627737	HeLa	viability after 12 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	1.7094506494062525	[138]	[238,197,126]	9	hSpCas9	negative selection	1548423
7526883	7526906	19	-	26627737	HeLa	viability after 12 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	1.2545519648004002	[275]	[232,406,160]	8	hSpCas9	negative selection	1548424
7527888	7527911	19	-	26627737	HeLa	viability after 12 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.9294764606783468	[101]	[120,23,102]	7	hSpCas9	negative selection	1548425
7528240	7528263	19	-	26627737	HeLa	viability after 12 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	-0.24079339350493706	[562]	[122,154,314]	-2	hSpCas9	negative selection	1548426
7528610	7528633	19	-	26627737	HeLa	viability after 12 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.6486533634349968	[477]	[183,237,510]	5	hSpCas9	negative selection	1548427
7525085	7525108	19	+	26627737	HeLa	viability after 15 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.9725848382517885	[834]	[638,508,868]	7	hSpCas9	negative selection	1630737
7526494	7526517	19	-	26627737	HeLa	viability after 15 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	1.0030727389346912	[138]	[131,142,60]	7	hSpCas9	negative selection	1630738
7526883	7526906	19	-	26627737	HeLa	viability after 15 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	0.6319692580405326	[275]	[164,152,206]	5	hSpCas9	negative selection	1630739
7527888	7527911	19	-	26627737	HeLa	viability after 15 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.1589171597897201	[101]	[44,22,43]	-1	hSpCas9	negative selection	1630740
7528240	7528263	19	-	26627737	HeLa	viability after 15 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.27285263022059714	[562]	[207,281,346]	2	hSpCas9	negative selection	1630741
7528610	7528633	19	-	26627737	HeLa	viability after 15 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	1.082173393623033	[477]	[390,339,512]	7	hSpCas9	negative selection	1630742
7525085	7525108	19	+	26627737	HeLa	viability after 18 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.9715611562882425	[834]	[420,429,868]	7	hSpCas9	negative selection	1713052
7526494	7526517	19	-	26627737	HeLa	viability after 18 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	1.0245329498152829	[138]	[92,116,60]	7	hSpCas9	negative selection	1713053
7526883	7526906	19	-	26627737	HeLa	viability after 18 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	0.582309692819232	[275]	[106,116,206]	5	hSpCas9	negative selection	1713054
7527888	7527911	19	-	26627737	HeLa	viability after 18 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.17554837406842805	[101]	[30,16,43]	-1	hSpCas9	negative selection	1713055
7528240	7528263	19	-	26627737	HeLa	viability after 18 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.2809617693948815	[562]	[142,232,346]	2	hSpCas9	negative selection	1713056
7528610	7528633	19	-	26627737	HeLa	viability after 18 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	1.0568003602487321	[477]	[255,271,512]	7	hSpCas9	negative selection	1713057
7525085	7525108	19	+	26627737	HCT116	viability after 6 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	1.2195601372137357	[1386]	[374,580]	6	hSpCas9	negative selection	1795367
7526494	7526517	19	-	26627737	HCT116	viability after 6 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-3.021989003773058	[286]	[11,1]	-9	hSpCas9	negative selection	1795368
7526883	7526906	19	-	26627737	HCT116	viability after 6 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	1.5475950819203839	[465]	[208,216]	7	hSpCas9	negative selection	1795369
7527888	7527911	19	-	26627737	HCT116	viability after 6 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.20634888057524292	[175]	[3,34]	-1	hSpCas9	negative selection	1795370
7528240	7528263	19	-	26627737	HCT116	viability after 6 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.9704373515607732	[484]	[296,67]	5	hSpCas9	negative selection	1795371
7528610	7528633	19	-	26627737	HCT116	viability after 6 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.3757403784016541	[1147]	[578,43]	2	hSpCas9	negative selection	1795372
7525085	7525108	19	+	26627737	HCT116	viability after 8 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	-0.37991760696027366	[927]	[390,323,462]	-4	hSpCas9	negative selection	1877682
7526494	7526517	19	-	26627737	HCT116	viability after 8 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	0.7767976961230216	[99]	[154,91,37]	7	hSpCas9	negative selection	1877683
7526883	7526906	19	-	26627737	HCT116	viability after 8 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	0.6505218840484204	[233]	[248,235,123]	6	hSpCas9	negative selection	1877684
7527888	7527911	19	-	26627737	HCT116	viability after 8 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	1.2732662029263742	[39]	[21,61,74]	8	hSpCas9	negative selection	1877685
7528240	7528263	19	-	26627737	HCT116	viability after 8 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.401071195570028	[335]	[232,235,263]	4	hSpCas9	negative selection	1877686
7528610	7528633	19	-	26627737	HCT116	viability after 8 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	-0.3042872835175674	[378]	[132,143,228]	-4	hSpCas9	negative selection	1877687
7525085	7525108	19	+	26627737	HCT116	viability after 9 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.9041368195202046	[1386]	[572,787]	6	hSpCas9	negative selection	1959997
7526494	7526517	19	-	26627737	HCT116	viability after 9 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-0.3830130684890245	[286]	[122,7]	-3	hSpCas9	negative selection	1959998
7526883	7526906	19	-	26627737	HCT116	viability after 9 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	1.4339331891565208	[465]	[362,314]	8	hSpCas9	negative selection	1959999
7527888	7527911	19	-	26627737	HCT116	viability after 9 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-2.0879381399710297	[175]	[0,18]	-8	hSpCas9	negative selection	1960000
7528240	7528263	19	-	26627737	HCT116	viability after 9 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.6120459223377631	[484]	[250,155]	4	hSpCas9	negative selection	1960001
7528610	7528633	19	-	26627737	HCT116	viability after 9 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	-0.5425803279049455	[1147]	[229,194]	-4	hSpCas9	negative selection	1960002
7525085	7525108	19	+	26627737	HCT116	viability after 12 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	-0.13221326712788173	[927]	[397,441,498]	-1	hSpCas9	negative selection	2042312
7526494	7526517	19	-	26627737	HCT116	viability after 12 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	1.012945056256691	[99]	[92,175,51]	8	hSpCas9	negative selection	2042313
7526883	7526906	19	-	26627737	HCT116	viability after 12 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	0.870786675274957	[233]	[320,175,167]	7	hSpCas9	negative selection	2042314
7527888	7527911	19	-	26627737	HCT116	viability after 12 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.5683806558540216	[39]	[21,17,53]	5	hSpCas9	negative selection	2042315
7528240	7528263	19	-	26627737	HCT116	viability after 12 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.8381071110111498	[335]	[515,133,274]	7	hSpCas9	negative selection	2042316
7528610	7528633	19	-	26627737	HCT116	viability after 12 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	-0.2785441687088977	[378]	[151,135,204]	-3	hSpCas9	negative selection	2042317
7525085	7525108	19	+	26627737	HCT116	viability after 15 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	-0.3297295060448977	[927]	[448,467,358]	-3	hSpCas9	negative selection	2124627
7526494	7526517	19	-	26627737	HCT116	viability after 15 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	1.055903036619248	[99]	[75,81,193]	8	hSpCas9	negative selection	2124628
7526883	7526906	19	-	26627737	HCT116	viability after 15 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	1.335607289565493	[233]	[274,421,312]	8	hSpCas9	negative selection	2124629
7527888	7527911	19	-	26627737	HCT116	viability after 15 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	1.306634539966308	[39]	[21,67,75]	8	hSpCas9	negative selection	2124630
7528240	7528263	19	-	26627737	HCT116	viability after 15 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.6234317927870522	[335]	[444,268,196]	5	hSpCas9	negative selection	2124631
7528610	7528633	19	-	26627737	HCT116	viability after 15 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	-0.036107002263951304	[378]	[299,92,253]	0	hSpCas9	negative selection	2124632
7525085	7525108	19	+	26627737	HCT116	viability after 18 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	-0.13803879755259252	[927]	[430,441,344]	-1	hSpCas9	negative selection	2206942
7526494	7526517	19	-	26627737	HCT116	viability after 18 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	1.099224438720717	[99]	[39,152,114]	8	hSpCas9	negative selection	2206943
7526883	7526906	19	-	26627737	HCT116	viability after 18 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	1.8958003602889006	[233]	[441,428,389]	9	hSpCas9	negative selection	2206944
7527888	7527911	19	-	26627737	HCT116	viability after 18 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.21893261941305653	[39]	[19,27,18]	2	hSpCas9	negative selection	2206945
7528240	7528263	19	-	26627737	HCT116	viability after 18 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.2887315890215104	[335]	[278,184,128]	2	hSpCas9	negative selection	2206946
7528610	7528633	19	-	26627737	HCT116	viability after 18 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	-0.47951654109200076	[378]	[70,183,135]	-4	hSpCas9	negative selection	2206947
7526546	7526569	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACACCTTCGCAGCCTACACGCGG	MCOLN1	ENSG00000090674	0.08610339640491188	[4,4]	[4,3]	1	hSpCas9	positive selection	3001672
7524950	7524973	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTATTCCCACAGAGACCGAGCGG	MCOLN1	ENSG00000090674	0.06339946860294998	[4,3]	[5,2]	1	hSpCas9	positive selection	3001673
7522769	7522792	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGCCCTCACCTGAGCCGCGCGG	MCOLN1	ENSG00000090674	-0.5581065113280036	[3,3]	[2,0]	-7	hSpCas9	positive selection	3001674
7526520	7526543	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGGCTACTCGGACGGAGCGG	MCOLN1	ENSG00000090674	-0.652808213873197	[2,2]	[0,1]	-7	hSpCas9	positive selection	3001675
7526546	7526569	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACACCTTCGCAGCCTACACGCGG	MCOLN1	ENSG00000090674	0.27107948213239735	[4,4]	[4,3]	5	hSpCas9	positive selection	3069530
7524950	7524973	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTATTCCCACAGAGACCGAGCGG	MCOLN1	ENSG00000090674	-0.3326894443223114	[4,4]	[2,1]	-5	hSpCas9	positive selection	3069531
7522769	7522792	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGCCCTCACCTGAGCCGCGCGG	MCOLN1	ENSG00000090674	0.0928898661014876	[3,3]	[2,1]	1	hSpCas9	positive selection	3069532
7526520	7526543	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGGCTACTCGGACGGAGCGG	MCOLN1	ENSG00000090674	0.18610140312222806	[2,2]	[1,2]	3	hSpCas9	positive selection	3069533
7526791	7526814		+	24336571	A375	resistance to PLX after 7 days	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	0.024128759558570356	[14,14]	[16,12]	0	hSpCas9	positive selection	3126827
7525084	7525107		-	24336571	A375	resistance to PLX after 7 days	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	-0.18076680955032742	[25,25]	[21,22]	-6	hSpCas9	positive selection	3126828
7526766	7526789		+	24336571	A375	resistance to PLX after 7 days	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.04553353574726815	[21,20]	[22,20]	1	hSpCas9	positive selection	3126829
7526791	7526814		+	24336571	A375	resistance to PLX after 14 days	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	0.15818138226849632	[18,18]	[8,10]	1	hSpCas9	positive selection	3184620
7525084	7525107		-	24336571	A375	resistance to PLX after 14 days	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	-0.0949129804142329	[26,24]	[11,9]	-1	hSpCas9	positive selection	3184621
7526766	7526789		+	24336571	A375	resistance to PLX after 14 days	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.7034241561256216	[15,20]	[13,13]	6	hSpCas9	positive selection	3184622
7526791	7526814		+	24336571	A375	viability after 7 days	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	0.17331030997487118	[13]	[14,14]	2	hSpCas9	negative selection	3242413
7525084	7525107		-	24336571	A375	viability after 7 days	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.5679311101937181	[17]	[25,25]	8	hSpCas9	negative selection	3242414
7526766	7526789		+	24336571	A375	viability after 7 days	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.7583934507598742	[12]	[21,20]	9	hSpCas9	negative selection	3242415
7526791	7526814		+	24336571	A375	viability after 14 days	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	0.5274770610189958	[13]	[18,18]	6	hSpCas9	negative selection	3300206
7525084	7525107		-	24336571	A375	viability after 14 days	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.5956340581375431	[17]	[26,24]	7	hSpCas9	negative selection	3300207
7526766	7526789		+	24336571	A375	viability after 14 days	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.5871601932303757	[12]	[15,20]	7	hSpCas9	negative selection	3300208
7525085	7525108	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	-0.6734111261170512	[243,243]	[0,0]	-4	hSpCas9	positive selection	3378804
7527915	7527938	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	-0.6555631247841265	[240,240]	[0,0]	-4	hSpCas9	positive selection	3378805
7527888	7527911	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.8822867800989105	[82,82]	[0,0]	4	hSpCas9	positive selection	3378806
7526545	7526568	19	+	26780180	HT29	viability (Avana library 4 designs)	ACACCTTCGCAGCCTACACGCGG	MCOLN1	ENSG00000090674	0.481594676521947	[]	[]	1	hSpCas9	negative selection	3439396
7524949	7524972	19	+	26780180	HT29	viability (Avana library 4 designs)	CTATTCCCACAGAGACCGAGCGG	MCOLN1	ENSG00000090674	0.340175909959837	[]	[]	1	hSpCas9	negative selection	3439397
7522769	7522792	19	-	26780180	HT29	viability (Avana library 4 designs)	GCGCCCTCACCTGAGCCGCGCGG	MCOLN1	ENSG00000090674	0.421584862048323	[]	[]	1	hSpCas9	negative selection	3439398
7526519	7526542	19	+	26780180	HT29	viability (Avana library 4 designs)	GCTGGGCTACTCGGACGGAGCGG	MCOLN1	ENSG00000090674	2.07197295369352	[]	[]	7	hSpCas9	negative selection	3439399
7524949	7524972	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTATTCCCACAGAGACCGAGCGG	MCOLN1	ENSG00000090674	-5.08953511888069	[]	[]	-5	hSpCas9	negative selection	3529122
7522769	7522792	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCCCTCACCTGAGCCGCGCGG	MCOLN1	ENSG00000090674	3.78896568601338	[]	[]	6	hSpCas9	negative selection	3529123
7526519	7526542	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGGCTACTCGGACGGAGCGG	MCOLN1	ENSG00000090674	3.87995758238423	[]	[]	6	hSpCas9	negative selection	3529124
7526545	7526568	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACACCTTCGCAGCCTACACGCGG	MCOLN1	ENSG00000090674	0.971211069711372	[]	[]	1	hSpCas9	negative selection	3529125
7526859	7526882	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTACTACCACCGAGGCCACGTGG	MCOLN1	ENSG00000090674	3.47623596128343	[]	[]	5	hSpCas9	negative selection	3529126
7525133	7525156	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-2.36436984581806	[]	[]	-3	hSpCas9	negative selection	3529127
7524949	7524972	19	+	26780180	A375	viability (Avana lentiGuide)	CTATTCCCACAGAGACCGAGCGG	MCOLN1	ENSG00000090674	-1.01980541783094	[]	[]	-1	hSpCas9	negative selection	3637781
7522769	7522792	19	-	26780180	A375	viability (Avana lentiGuide)	GCGCCCTCACCTGAGCCGCGCGG	MCOLN1	ENSG00000090674	4.74199895455655	[]	[]	4	hSpCas9	negative selection	3637782
7526519	7526542	19	+	26780180	A375	viability (Avana lentiGuide)	GCTGGGCTACTCGGACGGAGCGG	MCOLN1	ENSG00000090674	-1.28667897212215	[]	[]	-2	hSpCas9	negative selection	3637783
7526545	7526568	19	+	26780180	A375	viability (Avana lentiGuide)	ACACCTTCGCAGCCTACACGCGG	MCOLN1	ENSG00000090674	-0.339153431873572	[]	[]	0	hSpCas9	negative selection	3637784
7526859	7526882	19	+	26780180	A375	viability (Avana lentiGuide)	GTACTACCACCGAGGCCACGTGG	MCOLN1	ENSG00000090674	0.765803767792653	[]	[]	0	hSpCas9	negative selection	3637785
7525133	7525156	19	+	26780180	A375	viability (Avana lentiGuide)	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	10.6478622084305	[]	[]	7	hSpCas9	negative selection	3637786
7524949	7524972	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTATTCCCACAGAGACCGAGCGG	MCOLN1	ENSG00000090674	-0.48205097026566546	[4]	[2,2]	-6	hSpCas9	positive selection	3746440
7522769	7522792	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCCCTCACCTGAGCCGCGCGG	MCOLN1	ENSG00000090674	0.2782539759250898	[4]	[5,4]	7	hSpCas9	positive selection	3746441
7526519	7526542	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGGCTACTCGGACGGAGCGG	MCOLN1	ENSG00000090674	-0.5009752874688618	[3]	[2,2]	-6	hSpCas9	positive selection	3746442
7526545	7526568	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACACCTTCGCAGCCTACACGCGG	MCOLN1	ENSG00000090674	-0.006199912285110798	[5]	[5,5]	0	hSpCas9	positive selection	3746443
7526859	7526882	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACTACCACCGAGGCCACGTGG	MCOLN1	ENSG00000090674	0.1818930725348236	[4]	[5,3]	5	hSpCas9	positive selection	3746444
7525133	7525156	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-0.33985733448396693	[5]	[4,3]	-5	hSpCas9	positive selection	3746445
7524949	7524972	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTATTCCCACAGAGACCGAGCGG	MCOLN1	ENSG00000090674	0.2905567443170577	[5]	[6,5]	7	hSpCas9	positive selection	3855047
7522769	7522792	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCCCTCACCTGAGCCGCGCGG	MCOLN1	ENSG00000090674	-0.5268376014100138	[5]	[3,2]	-6	hSpCas9	positive selection	3855048
7526519	7526542	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGGCTACTCGGACGGAGCGG	MCOLN1	ENSG00000090674	0.12496703822003197	[4]	[1,5]	3	hSpCas9	positive selection	3855049
7526545	7526568	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACACCTTCGCAGCCTACACGCGG	MCOLN1	ENSG00000090674	0.23682262781796476	[6]	[6,6]	6	hSpCas9	positive selection	3855050
7526859	7526882	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACTACCACCGAGGCCACGTGG	MCOLN1	ENSG00000090674	0.32900717315872985	[5]	[5,5]	8	hSpCas9	positive selection	3855051
7525133	7525156	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-0.05128677082753408	[7]	[5,5]	0	hSpCas9	positive selection	3855052
7527915	7527938	19	-	26780180	A375	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.623588831953242	[]	[]	2	hSpCas9	negative selection	3960521
7526791	7526814	19	+	26780180	A375	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	1.46191789005778	[]	[]	8	hSpCas9	negative selection	3960522
7525085	7525108	19	+	26780180	A375	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.984102902411934	[]	[]	4	hSpCas9	negative selection	3960523
7525084	7525107	19	-	26780180	A375	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	1.77242089680237	[]	[]	9	hSpCas9	negative selection	3960524
7527888	7527911	19	-	26780180	A375	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	1.24983302875108	[]	[]	6	hSpCas9	negative selection	3960525
7526766	7526789	19	+	26780180	A375	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.465608095987771	[]	[]	1	hSpCas9	negative selection	3960526
7527915	7527938	19	-	26780180	HT29	viability (GeCKOv2 library)	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.520763389036532	[]	[]	1	hSpCas9	negative selection	4068487
7526791	7526814	19	+	26780180	HT29	viability (GeCKOv2 library)	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	1.2033177649912	[]	[]	6	hSpCas9	negative selection	4068488
7525085	7525108	19	+	26780180	HT29	viability (GeCKOv2 library)	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.999535977652267	[]	[]	4	hSpCas9	negative selection	4068489
7525084	7525107	19	-	26780180	HT29	viability (GeCKOv2 library)	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	1.34909521092524	[]	[]	7	hSpCas9	negative selection	4068490
7527888	7527911	19	-	26780180	HT29	viability (GeCKOv2 library)	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.873334772454019	[]	[]	3	hSpCas9	negative selection	4068491
7526766	7526789	19	+	26780180	HT29	viability (GeCKOv2 library)	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.6568882325885	[]	[]	2	hSpCas9	negative selection	4068492
7526791	7526814	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	0.06421829686535496	[4]	[2,3]	1	hSpCas9	positive selection	4151123
7525084	7525107	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	-0.042854349656498036	[4]	[1,3]	-1	hSpCas9	positive selection	4151124
7526766	7526789	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.24867462727351422	[4]	[3,3]	6	hSpCas9	positive selection	4151125
7526791	7526814	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.378053899969958	[2]	[0,0,1,0]	-5	hSpCas9	positive selection	4215145
7525084	7525107	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	1.271455077656516	[3]	[3,4,0,3]	9	hSpCas9	positive selection	4215146
7526766	7526789	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.8040585103852295	[3]	[0,1,2,3]	5	hSpCas9	positive selection	4215147
7525084	7525107	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.018233107214698008	[3]	[3,2]	0	hSpCas9	positive selection	4282296
7526766	7526789	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	-0.008092007699337822	[2]	[2,0]	0	hSpCas9	positive selection	4282297
7526791	7526814	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	0.33054127454026117	[3]	[3,4]	6	hSpCas9	positive selection	4282298
7525085	7525108	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.01035179484338744	[3]	[3,1]	0	hSpCas9	positive selection	4346554
7527915	7527938	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.07074070872697988	[3]	[3,1]	1	hSpCas9	positive selection	4346555
7527888	7527911	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.20969378733549737	[2]	[1,0]	-4	hSpCas9	positive selection	4346556
7525087	7525109	19	+	27760321	OCIAML3	viability	GCGACAAGTTTCGAGCCAAGGG	MCOLN1	ENSG00000090674	0.5821488565459768	[505,442]	[480,649]	7	hSpCas9	negative selection	4417351
7526767	7526789	19	+	27760321	OCIAML3	viability	GCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.9536020204011448	[594,609]	[830,1027]	9	hSpCas9	negative selection	4417352
7526789	7526811	19	+	27760321	OCIAML3	viability	GCCGGTATGCGTATGTCCGTGG	MCOLN1	ENSG00000090674	-0.601831973240918	[1093,812]	[427,563]	-5	hSpCas9	negative selection	4417353
7526852	7526874	19	+	27760321	OCIAML3	viability	GCCAGCGGTACTACCACCGAGG	MCOLN1	ENSG00000090674	-0.04583270084071378	[807,660]	[551,555]	0	hSpCas9	negative selection	4417354
7527562	7527584	19	-	27760321	OCIAML3	viability	AAGAGGGTGAGATCGTCGCTGG	MCOLN1	ENSG00000090674	-0.1066656896785596	[1481,1300]	[1081,912]	-1	hSpCas9	negative selection	4417355
7525087	7525109	19	+	27760321	OCIAML2	viability	GCGACAAGTTTCGAGCCAAGGG	MCOLN1	ENSG00000090674	0.867455236767051	[505,442]	[602,824]	9	hSpCas9	negative selection	4500814
7526767	7526789	19	+	27760321	OCIAML2	viability	GCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.4499311801090275	[594,609]	[574,791]	6	hSpCas9	negative selection	4500815
7526789	7526811	19	+	27760321	OCIAML2	viability	GCCGGTATGCGTATGTCCGTGG	MCOLN1	ENSG00000090674	-0.2766184734539786	[1093,812]	[587,687]	-3	hSpCas9	negative selection	4500816
7526852	7526874	19	+	27760321	OCIAML2	viability	GCCAGCGGTACTACCACCGAGG	MCOLN1	ENSG00000090674	-0.013765758364502556	[807,660]	[450,762]	0	hSpCas9	negative selection	4500817
7527562	7527584	19	-	27760321	OCIAML2	viability	AAGAGGGTGAGATCGTCGCTGG	MCOLN1	ENSG00000090674	0.07771970833238284	[1481,1300]	[1169,1205]	1	hSpCas9	negative selection	4500818
7525087	7525109	19	+	27760321	MV411	viability	GCGACAAGTTTCGAGCCAAGGG	MCOLN1	ENSG00000090674	1.4666314315711593	[505,442]	[1010,641]	9	hSpCas9	negative selection	4584277
7526767	7526789	19	+	27760321	MV411	viability	GCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.8199518464350501	[594,609]	[833,510]	6	hSpCas9	negative selection	4584278
7526789	7526811	19	+	27760321	MV411	viability	GCCGGTATGCGTATGTCCGTGG	MCOLN1	ENSG00000090674	0.15807489030503996	[1093,812]	[804,531]	1	hSpCas9	negative selection	4584279
7526852	7526874	19	+	27760321	MV411	viability	GCCAGCGGTACTACCACCGAGG	MCOLN1	ENSG00000090674	0.8576059007969238	[807,660]	[819,954]	6	hSpCas9	negative selection	4584280
7527562	7527584	19	-	27760321	MV411	viability	AAGAGGGTGAGATCGTCGCTGG	MCOLN1	ENSG00000090674	0.6537294143384733	[1481,1300]	[1505,1344]	5	hSpCas9	negative selection	4584281
7525087	7525109	19	+	27760321	HL60	viability	GCGACAAGTTTCGAGCCAAGGG	MCOLN1	ENSG00000090674	0.7521585124367739	[505,442]	[781,512]	8	hSpCas9	negative selection	4667740
7526767	7526789	19	+	27760321	HL60	viability	GCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.03577673942987264	[594,609]	[562,446]	0	hSpCas9	negative selection	4667741
7526789	7526811	19	+	27760321	HL60	viability	GCCGGTATGCGTATGTCCGTGG	MCOLN1	ENSG00000090674	0.20592264634937973	[1093,812]	[723,1066]	2	hSpCas9	negative selection	4667742
7526852	7526874	19	+	27760321	HL60	viability	GCCAGCGGTACTACCACCGAGG	MCOLN1	ENSG00000090674	-0.5712439085323592	[807,660]	[478,319]	-6	hSpCas9	negative selection	4667743
7527562	7527584	19	-	27760321	HL60	viability	AAGAGGGTGAGATCGTCGCTGG	MCOLN1	ENSG00000090674	1.1251999741284886	[1481,1300]	[2635,2302]	9	hSpCas9	negative selection	4667744
7525087	7525109	19	+	27760321	HT1080	viability	GCGACAAGTTTCGAGCCAAGGG	MCOLN1	ENSG00000090674	1.6467725204156665	[442,345]	[515,465]	8	hSpCas9	negative selection	4751203
7526767	7526789	19	+	27760321	HT1080	viability	GCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	-0.26459220312415216	[609,475]	[191,166]	-1	hSpCas9	negative selection	4751204
7526789	7526811	19	+	27760321	HT1080	viability	GCCGGTATGCGTATGTCCGTGG	MCOLN1	ENSG00000090674	1.0733399603069227	[812,634]	[626,584]	6	hSpCas9	negative selection	4751205
7526852	7526874	19	+	27760321	HT1080	viability	GCCAGCGGTACTACCACCGAGG	MCOLN1	ENSG00000090674	0.9489115929294765	[660,515]	[548,346]	5	hSpCas9	negative selection	4751206
7527562	7527584	19	-	27760321	HT1080	viability	AAGAGGGTGAGATCGTCGCTGG	MCOLN1	ENSG00000090674	0.8311980897464335	[1300,1014]	[519,1149]	4	hSpCas9	negative selection	4751207
7525087	7525109	19	+	27760321	HT29	viability after 7 days	GCGACAAGTTTCGAGCCAAGGG	MCOLN1	ENSG00000090674	-0.07299015051273416	[442,345]	[501,503,443]	-1	hSpCas9	negative selection	4834666
7526767	7526789	19	+	27760321	HT29	viability after 7 days	GCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.13837809520452182	[609,475]	[963,630,737]	2	hSpCas9	negative selection	4834667
7526789	7526811	19	+	27760321	HT29	viability after 7 days	GCCGGTATGCGTATGTCCGTGG	MCOLN1	ENSG00000090674	0.21468166659828558	[812,634]	[1082,929,1221]	3	hSpCas9	negative selection	4834668
7526852	7526874	19	+	27760321	HT29	viability after 7 days	GCCAGCGGTACTACCACCGAGG	MCOLN1	ENSG00000090674	0.3578057237225598	[660,515]	[996,995,919]	5	hSpCas9	negative selection	4834669
7527562	7527584	19	-	27760321	HT29	viability after 7 days	AAGAGGGTGAGATCGTCGCTGG	MCOLN1	ENSG00000090674	-0.29542696633112997	[1300,1014]	[1420,1023,1221]	-4	hSpCas9	negative selection	4834670
7525087	7525109	19	+	27760321	HT29	viability after 25 days	GCGACAAGTTTCGAGCCAAGGG	MCOLN1	ENSG00000090674	0.24681426906834522	[442,345]	[570,425,612]	2	hSpCas9	negative selection	4918129
7526767	7526789	19	+	27760321	HT29	viability after 25 days	GCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	-0.08694917146492354	[609,475]	[569,630,547]	-1	hSpCas9	negative selection	4918130
7526789	7526811	19	+	27760321	HT29	viability after 25 days	GCCGGTATGCGTATGTCCGTGG	MCOLN1	ENSG00000090674	0.5859419358818656	[812,634]	[1043,1386,1312]	6	hSpCas9	negative selection	4918131
7526852	7526874	19	+	27760321	HT29	viability after 25 days	GCCAGCGGTACTACCACCGAGG	MCOLN1	ENSG00000090674	0.6581000489329147	[660,515]	[971,1041,1186]	7	hSpCas9	negative selection	4918132
7527562	7527584	19	-	27760321	HT29	viability after 25 days	AAGAGGGTGAGATCGTCGCTGG	MCOLN1	ENSG00000090674	0.06054743014360464	[1300,1014]	[1219,1351,1598]	0	hSpCas9	negative selection	4918133
7525087	7525109	19	+	27760321	HT29	viability after 22 days	GCGACAAGTTTCGAGCCAAGGG	MCOLN1	ENSG00000090674	0.2728966816390016	[442,345]	[439,574,641]	3	hSpCas9	negative selection	5001592
7526767	7526789	19	+	27760321	HT29	viability after 22 days	GCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	-0.07046268041787207	[609,475]	[569,745,476]	0	hSpCas9	negative selection	5001593
7526789	7526811	19	+	27760321	HT29	viability after 22 days	GCCGGTATGCGTATGTCCGTGG	MCOLN1	ENSG00000090674	0.6147697826483303	[812,634]	[1500,1185,1150]	7	hSpCas9	negative selection	5001594
7526852	7526874	19	+	27760321	HT29	viability after 22 days	GCCAGCGGTACTACCACCGAGG	MCOLN1	ENSG00000090674	0.45604134024342957	[660,515]	[791,828,1184]	5	hSpCas9	negative selection	5001595
7527562	7527584	19	-	27760321	HT29	viability after 22 days	AAGAGGGTGAGATCGTCGCTGG	MCOLN1	ENSG00000090674	0.026867819612734545	[1300,1014]	[1281,1517,1292]	0	hSpCas9	negative selection	5001596
7525087	7525109	19	+	27760321	HT29	viability after 19 days	GCGACAAGTTTCGAGCCAAGGG	MCOLN1	ENSG00000090674	0.2651391172380253	[442,345]	[698,488,457]	2	hSpCas9	negative selection	5085055
7526767	7526789	19	+	27760321	HT29	viability after 19 days	GCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	-0.4048436353371263	[609,475]	[495,747,176]	-4	hSpCas9	negative selection	5085056
7526789	7526811	19	+	27760321	HT29	viability after 19 days	GCCGGTATGCGTATGTCCGTGG	MCOLN1	ENSG00000090674	0.026977740709237752	[812,634]	[1056,629,864]	0	hSpCas9	negative selection	5085057
7526852	7526874	19	+	27760321	HT29	viability after 19 days	GCCAGCGGTACTACCACCGAGG	MCOLN1	ENSG00000090674	0.8969780857684568	[660,515]	[1004,1120,1593]	8	hSpCas9	negative selection	5085058
7527562	7527584	19	-	27760321	HT29	viability after 19 days	AAGAGGGTGAGATCGTCGCTGG	MCOLN1	ENSG00000090674	0.1712026846699748	[1300,1014]	[1406,1570,1485]	1	hSpCas9	negative selection	5085059
7525087	7525109	19	+	27760321	HT29	viability after 16 days	GCGACAAGTTTCGAGCCAAGGG	MCOLN1	ENSG00000090674	0.5045823909968498	[442,345]	[619,584,673]	6	hSpCas9	negative selection	5168518
7526767	7526789	19	+	27760321	HT29	viability after 16 days	GCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	-0.1975012905151482	[609,475]	[515,527,543]	-2	hSpCas9	negative selection	5168519
7526789	7526811	19	+	27760321	HT29	viability after 16 days	GCCGGTATGCGTATGTCCGTGG	MCOLN1	ENSG00000090674	0.48387457499218	[812,634]	[1193,1023,1188]	5	hSpCas9	negative selection	5168520
7526852	7526874	19	+	27760321	HT29	viability after 16 days	GCCAGCGGTACTACCACCGAGG	MCOLN1	ENSG00000090674	0.6411374401134524	[660,515]	[1131,732,1232]	7	hSpCas9	negative selection	5168521
7527562	7527584	19	-	27760321	HT29	viability after 16 days	AAGAGGGTGAGATCGTCGCTGG	MCOLN1	ENSG00000090674	0.01981355633212356	[1300,1014]	[1521,1231,1207]	0	hSpCas9	negative selection	5168522
7525087	7525109	19	+	27760321	HT29	viability after 13 days	GCGACAAGTTTCGAGCCAAGGG	MCOLN1	ENSG00000090674	0.3597789118133339	[442,345]	[494,661,603]	4	hSpCas9	negative selection	5251981
7526767	7526789	19	+	27760321	HT29	viability after 13 days	GCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.06266785867424518	[609,475]	[414,932,627]	0	hSpCas9	negative selection	5251982
7526789	7526811	19	+	27760321	HT29	viability after 13 days	GCCGGTATGCGTATGTCCGTGG	MCOLN1	ENSG00000090674	0.2487520189961998	[812,634]	[818,1001,1162]	3	hSpCas9	negative selection	5251983
7526852	7526874	19	+	27760321	HT29	viability after 13 days	GCCAGCGGTACTACCACCGAGG	MCOLN1	ENSG00000090674	0.3883431932860646	[660,515]	[1125,623,927]	5	hSpCas9	negative selection	5251984
7527562	7527584	19	-	27760321	HT29	viability after 13 days	AAGAGGGTGAGATCGTCGCTGG	MCOLN1	ENSG00000090674	0.23380450455325064	[1300,1014]	[1745,1779,1233]	3	hSpCas9	negative selection	5251985
7525087	7525109	19	+	27760321	HT29	viability after 10 days	GCGACAAGTTTCGAGCCAAGGG	MCOLN1	ENSG00000090674	0.5448658362875698	[442,345]	[505,1139,525]	7	hSpCas9	negative selection	5335444
7526767	7526789	19	+	27760321	HT29	viability after 10 days	GCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	-0.07408501044670812	[609,475]	[728,706,500]	-1	hSpCas9	negative selection	5335445
7526789	7526811	19	+	27760321	HT29	viability after 10 days	GCCGGTATGCGTATGTCCGTGG	MCOLN1	ENSG00000090674	0.5088486897561695	[812,634]	[1331,1010,1502]	7	hSpCas9	negative selection	5335446
7526852	7526874	19	+	27760321	HT29	viability after 10 days	GCCAGCGGTACTACCACCGAGG	MCOLN1	ENSG00000090674	0.36202388441215394	[660,515]	[1031,745,1046]	5	hSpCas9	negative selection	5335447
7527562	7527584	19	-	27760321	HT29	viability after 10 days	AAGAGGGTGAGATCGTCGCTGG	MCOLN1	ENSG00000090674	-0.0668543579476224	[1300,1014]	[1807,1133,1195]	-1	hSpCas9	negative selection	5335448
7525087	7525109	19	+	27760321	MOLM13	viability	GCGACAAGTTTCGAGCCAAGGG	MCOLN1	ENSG00000090674	0.41907643918447623	[505,442]	[179,507]	3	hSpCas9	negative selection	5418907
7526767	7526789	19	+	27760321	MOLM13	viability	GCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.16423968501154856	[594,609]	[401,365]	1	hSpCas9	negative selection	5418908
7526789	7526811	19	+	27760321	MOLM13	viability	GCCGGTATGCGTATGTCCGTGG	MCOLN1	ENSG00000090674	-0.928402028413854	[1093,812]	[297,264]	-5	hSpCas9	negative selection	5418909
7526852	7526874	19	+	27760321	MOLM13	viability	GCCAGCGGTACTACCACCGAGG	MCOLN1	ENSG00000090674	-1.0430133453014567	[807,660]	[258,149]	-6	hSpCas9	negative selection	5418910
7527562	7527584	19	-	27760321	MOLM13	viability	AAGAGGGTGAGATCGTCGCTGG	MCOLN1	ENSG00000090674	-0.19959758066692368	[1481,1300]	[631,724]	-1	hSpCas9	negative selection	5418911
7522667	7522690	19	+	27661255	K562	viability	GAGCGAGGTCGCAGTGACAGCGG	MCOLN1	ENSG00000090674	-0.024055054218780736	[1167,1146]	[995,835]	-1	dCas9-KRAB	negative selection	5492665
7522711	7522734	19	-	27661255	K562	viability	GGACGCAGGCGGGTACGGCGGGG	MCOLN1	ENSG00000090674	0.5777695786156283	[609,657]	[729,775]	9	dCas9-KRAB	negative selection	5492666
7522716	7522739	19	-	27661255	K562	viability	GCGCGGGACGCAGGCGGGTACGG	MCOLN1	ENSG00000090674	0.3507933813705927	[481,536]	[517,517]	9	dCas9-KRAB	negative selection	5492667
7525084	7525107	19	-	27260156	BXPC3	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.1328667138915387	[892]	[1037,902,1124,1029]	3	hSpCas9	negative selection	5554756
7526766	7526789	19	+	27260156	BXPC3	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.3688963439951771	[219]	[179,279,425,318]	7	hSpCas9	negative selection	5554757
7526791	7526814	19	+	27260156	BXPC3	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.13246400542189762	[852]	[732,835,769,930]	-3	hSpCas9	negative selection	5554758
7525085	7525108	19	+	27260156	BXPC3	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.028676284845570554	[510]	[382,526,591,714]	0	hSpCas9	negative selection	5619014
7527915	7527938	19	-	27260156	BXPC3	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.08297682163463951	[517]	[644,420,548,690]	1	hSpCas9	negative selection	5619015
7527888	7527911	19	-	27260156	BXPC3	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.36927848781464734	[258]	[174,196,141,342]	-7	hSpCas9	negative selection	5619016
7525084	7525107	19	-	27260156	A673	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.18714012550424552	[892]	[1289,1084,1214,1306]	4	hSpCas9	negative selection	5676007
7526766	7526789	19	+	27260156	A673	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.4584994351397057	[219]	[396,383,311,361]	9	hSpCas9	negative selection	5676008
7526791	7526814	19	+	27260156	A673	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.2425519017647081	[852]	[921,955,672,918]	-5	hSpCas9	negative selection	5676009
7525085	7525108	19	+	27260156	A673	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.19145166370840813	[510]	[897,614,729,575]	4	hSpCas9	negative selection	5740265
7527915	7527938	19	-	27260156	A673	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.23135221694410174	[517]	[818,737,613,760]	5	hSpCas9	negative selection	5740266
7527888	7527911	19	-	27260156	A673	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.025493888982019652	[258]	[386,281,242,320]	0	hSpCas9	negative selection	5740267
7525084	7525107	19	-	27260156	A375	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.16495193512132955	[892]	[1442,1160,967,1108]	2	hSpCas9	negative selection	5797258
7526766	7526789	19	+	27260156	A375	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.42379883401188134	[219]	[244,552,265,341]	6	hSpCas9	negative selection	5797259
7526791	7526814	19	+	27260156	A375	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.2714089731730944	[852]	[710,996,625,969]	-4	hSpCas9	negative selection	5797260
7525085	7525108	19	+	27260156	A375	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.580703519606585	[510]	[715,1247,821,835]	8	hSpCas9	negative selection	5861516
7527915	7527938	19	-	27260156	A375	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	-0.00429548621896414	[517]	[499,699,580,637]	0	hSpCas9	negative selection	5861517
7527888	7527911	19	-	27260156	A375	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.30237810617516736	[258]	[334,163,237,233]	-4	hSpCas9	negative selection	5861518
7525084	7525107	19	-	27260156	COLO741	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.17480927600019314	[892]	[1453,1205,1219]	3	hSpCas9	negative selection	5918509
7526766	7526789	19	+	27260156	COLO741	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.31092224949301017	[219]	[408,371,274]	6	hSpCas9	negative selection	5918510
7526791	7526814	19	+	27260156	COLO741	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.36757731831304297	[852]	[1032,726,791]	-7	hSpCas9	negative selection	5918511
7525085	7525108	19	+	27260156	COLO741	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.2024552176930435	[510]	[992,567,713]	4	hSpCas9	negative selection	5982767
7527915	7527938	19	-	27260156	COLO741	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.10962779583469484	[517]	[852,651,651]	2	hSpCas9	negative selection	5982768
7527888	7527911	19	-	27260156	COLO741	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.1574497227801288	[258]	[355,458,295]	3	hSpCas9	negative selection	5982769
7525084	7525107	19	-	27260156	CAL120	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	-0.021144906772201044	[892]	[953,1128,1178]	0	hSpCas9	negative selection	6039760
7526766	7526789	19	+	27260156	CAL120	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.30206860750384623	[219]	[432,266,326]	4	hSpCas9	negative selection	6039761
7526791	7526814	19	+	27260156	CAL120	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.2726281281622346	[852]	[976,878,795]	-4	hSpCas9	negative selection	6039762
7525085	7525108	19	+	27260156	CAL120	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.5079036566700763	[510]	[712,870,1095]	7	hSpCas9	negative selection	6104018
7527915	7527938	19	-	27260156	CAL120	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	-0.08750091025439424	[517]	[684,622,524]	-1	hSpCas9	negative selection	6104019
7527888	7527911	19	-	27260156	CAL120	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.05608980453331158	[258]	[552,212,272]	0	hSpCas9	negative selection	6104020
7525084	7525107	19	-	27260156	CADOES1	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.15303913523169776	[892]	[875,961,859,998]	2	hSpCas9	negative selection	6161011
7526766	7526789	19	+	27260156	CADOES1	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.22373345138523415	[219]	[258,221,328,141]	4	hSpCas9	negative selection	6161012
7526791	7526814	19	+	27260156	CADOES1	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.3428287432735203	[852]	[711,571,562,655]	-5	hSpCas9	negative selection	6161013
7525085	7525108	19	+	27260156	CADOES1	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.3998781368925778	[510]	[623,524,578,785]	6	hSpCas9	negative selection	6225269
7527915	7527938	19	-	27260156	CADOES1	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.013558051161634499	[517]	[537,472,450,482]	0	hSpCas9	negative selection	6225270
7527888	7527911	19	-	27260156	CADOES1	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.20190244640728716	[258]	[225,146,191,274]	-4	hSpCas9	negative selection	6225271
7525084	7525107	19	-	27260156	EWS502	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.29369560061033284	[892]	[1061,1150,1062,1383]	5	hSpCas9	negative selection	6282262
7526766	7526789	19	+	27260156	EWS502	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.728052534360677	[219]	[205,451,573,327]	9	hSpCas9	negative selection	6282263
7526791	7526814	19	+	27260156	EWS502	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.2954207471046669	[852]	[654,681,753,872]	-5	hSpCas9	negative selection	6282264
7525085	7525108	19	+	27260156	EWS502	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.2617908178836085	[510]	[613,673,523,792]	4	hSpCas9	negative selection	6346520
7527915	7527938	19	-	27260156	EWS502	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.05030657134531416	[517]	[626,576,612,436]	0	hSpCas9	negative selection	6346521
7527888	7527911	19	-	27260156	EWS502	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.43035057749832206	[258]	[175,163,186,297]	-6	hSpCas9	negative selection	6346522
7525084	7525107	19	-	27260156	EW8	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.18509933832162195	[892]	[918,950,717,729]	3	hSpCas9	negative selection	6403513
7526766	7526789	19	+	27260156	EW8	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.5873437036969384	[219]	[204,317,231,314]	9	hSpCas9	negative selection	6403514
7526791	7526814	19	+	27260156	EW8	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.3691992178298436	[852]	[553,548,369,695]	-6	hSpCas9	negative selection	6403515
7525085	7525108	19	+	27260156	EW8	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.44131849608714524	[510]	[580,483,514,676]	7	hSpCas9	negative selection	6467771
7527915	7527938	19	-	27260156	EW8	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.1076506672770633	[517]	[444,515,371,487]	2	hSpCas9	negative selection	6467772
7527888	7527911	19	-	27260156	EW8	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.3010799217864466	[258]	[262,87,138,205]	-5	hSpCas9	negative selection	6467773
7525084	7525107	19	-	27260156	CORL105	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.2100362785487988	[892]	[1202,951,1625,1125]	4	hSpCas9	negative selection	6524764
7526766	7526789	19	+	27260156	CORL105	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.40845816555635983	[219]	[303,320,509,257]	7	hSpCas9	negative selection	6524765
7526791	7526814	19	+	27260156	CORL105	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.4206751881048925	[852]	[794,687,810,702]	-6	hSpCas9	negative selection	6524766
7525085	7525108	19	+	27260156	CORL105	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.18261253476092923	[510]	[753,609,800,573]	3	hSpCas9	negative selection	6589022
7527915	7527938	19	-	27260156	CORL105	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.11979163607670074	[517]	[682,472,644,835]	2	hSpCas9	negative selection	6589023
7527888	7527911	19	-	27260156	CORL105	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.578617844324766	[258]	[198,228,174,203]	-8	hSpCas9	negative selection	6589024
7525084	7525107	19	-	27260156	HS294T	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.2659939059680845	[892]	[411,413,311,542]	3	hSpCas9	negative selection	6646015
7526766	7526789	19	+	27260156	HS294T	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.7618979013673038	[219]	[85,89,218,197]	8	hSpCas9	negative selection	6646016
7526791	7526814	19	+	27260156	HS294T	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	0.22856645261324815	[852]	[512,202,322,521]	3	hSpCas9	negative selection	6646017
7525085	7525108	19	+	27260156	HS294T	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.541358616069606	[510]	[275,255,433,164]	7	hSpCas9	negative selection	6710273
7527915	7527938	19	-	27260156	HS294T	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.11032696088387783	[517]	[133,251,152,354]	1	hSpCas9	negative selection	6710274
7527888	7527911	19	-	27260156	HS294T	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.5382580762884064	[258]	[32,81,57,112]	-6	hSpCas9	negative selection	6710275
7525084	7525107	19	-	27260156	HCC44	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.22428199315261232	[892]	[1256,930,1512,1110]	3	hSpCas9	negative selection	6767266
7526766	7526789	19	+	27260156	HCC44	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.6037130993602529	[219]	[598,283,427,244]	8	hSpCas9	negative selection	6767267
7526791	7526814	19	+	27260156	HCC44	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.13098567789196736	[852]	[968,762,990,838]	-2	hSpCas9	negative selection	6767268
7525085	7525108	19	+	27260156	HCC44	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.25506082357897986	[510]	[814,435,858,718]	4	hSpCas9	negative selection	6831524
7527915	7527938	19	-	27260156	HCC44	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.24828383146579602	[517]	[846,420,804,773]	4	hSpCas9	negative selection	6831525
7527888	7527911	19	-	27260156	HCC44	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.49300788298285414	[258]	[212,158,264,210]	-6	hSpCas9	negative selection	6831526
7525084	7525107	19	-	27260156	G402	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.17253851175630985	[892]	[1058,925,1047,1803]	2	hSpCas9	negative selection	6888517
7526766	7526789	19	+	27260156	G402	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	1.3864555875565003	[219]	[574,540,601,1041]	9	hSpCas9	negative selection	6888518
7526791	7526814	19	+	27260156	G402	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.42346085066751576	[852]	[698,444,1215,713]	-5	hSpCas9	negative selection	6888519
7525085	7525108	19	+	27260156	G402	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.3736612715797043	[510]	[1031,763,778,688]	5	hSpCas9	negative selection	6952775
7527915	7527938	19	-	27260156	G402	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.3998211570068678	[517]	[1006,957,679,724]	5	hSpCas9	negative selection	6952776
7527888	7527911	19	-	27260156	G402	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.11059976528292048	[258]	[527,443,263,168]	1	hSpCas9	negative selection	6952777
7525084	7525107	19	-	27260156	L33	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.23534002101384432	[892]	[1062,419,626,1117]	5	hSpCas9	negative selection	7009768
7526766	7526789	19	+	27260156	L33	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	-0.1925295406304619	[219]	[194,92,125,147]	-4	hSpCas9	negative selection	7009769
7526791	7526814	19	+	27260156	L33	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.1806003354799579	[852]	[713,340,472,712]	-4	hSpCas9	negative selection	7009770
7525085	7525108	19	+	27260156	L33	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.09547108037092081	[510]	[514,197,396,554]	2	hSpCas9	negative selection	7074026
7527915	7527938	19	-	27260156	L33	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.13731028496899278	[517]	[628,198,348,606]	3	hSpCas9	negative selection	7074027
7527888	7527911	19	-	27260156	L33	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.20468660843867048	[258]	[232,98,133,210]	-5	hSpCas9	negative selection	7074028
7525084	7525107	19	-	27260156	K562	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	-0.1503743073325745	[892]	[844,625,681,706]	-2	hSpCas9	negative selection	7131019
7526766	7526789	19	+	27260156	K562	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.7576460922210448	[219]	[108,750,255,219]	8	hSpCas9	negative selection	7131020
7526791	7526814	19	+	27260156	K562	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.32411710110460945	[852]	[660,427,713,607]	-4	hSpCas9	negative selection	7131021
7525085	7525108	19	+	27260156	K562	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.3958689001686019	[510]	[813,479,667,450]	5	hSpCas9	negative selection	7195277
7527915	7527938	19	-	27260156	K562	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	-0.2989998284470078	[517]	[343,514,359,288]	-4	hSpCas9	negative selection	7195278
7527888	7527911	19	-	27260156	K562	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.8105745645294595	[258]	[111,106,49,238]	-7	hSpCas9	negative selection	7195279
7525084	7525107	19	-	27260156	HT29	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.153021526484594	[892]	[1327,1533,961,1051]	3	hSpCas9	negative selection	7252270
7526766	7526789	19	+	27260156	HT29	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.30372157963405844	[219]	[372,321,343,286]	6	hSpCas9	negative selection	7252271
7526791	7526814	19	+	27260156	HT29	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.3029752523820106	[852]	[810,869,958,729]	-5	hSpCas9	negative selection	7252272
7525085	7525108	19	+	27260156	HT29	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.4425310602692669	[510]	[1023,983,621,774]	8	hSpCas9	negative selection	7316528
7527915	7527938	19	-	27260156	HT29	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.16765785770143016	[517]	[763,1018,713,396]	3	hSpCas9	negative selection	7316529
7527888	7527911	19	-	27260156	HT29	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.04544773790598966	[258]	[319,463,272,259]	0	hSpCas9	negative selection	7316530
7525084	7525107	19	-	27260156	MHHES1	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.2542804931756393	[892]	[1514,1264,1294,828]	5	hSpCas9	negative selection	7373521
7526766	7526789	19	+	27260156	MHHES1	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.22115070183914798	[219]	[433,406,195,168]	4	hSpCas9	negative selection	7373522
7526791	7526814	19	+	27260156	MHHES1	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.26543786303211314	[852]	[829,939,786,669]	-5	hSpCas9	negative selection	7373523
7525085	7525108	19	+	27260156	MHHES1	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.3231067753879533	[510]	[882,735,724,574]	6	hSpCas9	negative selection	7437779
7527915	7527938	19	-	27260156	MHHES1	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.17554899023292259	[517]	[681,788,625,561]	3	hSpCas9	negative selection	7437780
7527888	7527911	19	-	27260156	MHHES1	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.6604158499042705	[258]	[222,277,100,152]	-8	hSpCas9	negative selection	7437781
7525084	7525107	19	-	27260156	MEWO	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.06916487922175985	[892]	[962,675,1007]	1	hSpCas9	negative selection	7494772
7526766	7526789	19	+	27260156	MEWO	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.659810043929844	[219]	[325,245,403]	9	hSpCas9	negative selection	7494773
7526791	7526814	19	+	27260156	MEWO	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	0.021502439330777556	[852]	[1042,811,619]	0	hSpCas9	negative selection	7494774
7525085	7525108	19	+	27260156	MEWO	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.3537080744060672	[510]	[795,492,579]	7	hSpCas9	negative selection	7559030
7527915	7527938	19	-	27260156	MEWO	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.295931458957311	[517]	[847,546,438]	6	hSpCas9	negative selection	7559031
7527888	7527911	19	-	27260156	MEWO	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.22748131392142934	[258]	[350,295,216]	5	hSpCas9	negative selection	7559032
7525084	7525107	19	-	27260156	LNCAPCLONEFGC	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.28085035868173436	[892]	[753,1058,1367,805]	4	hSpCas9	negative selection	7616023
7526766	7526789	19	+	27260156	LNCAPCLONEFGC	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.6434948772836703	[219]	[315,227,341,368]	8	hSpCas9	negative selection	7616024
7526791	7526814	19	+	27260156	LNCAPCLONEFGC	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.30934373988729835	[852]	[740,605,530,600]	-5	hSpCas9	negative selection	7616025
7525085	7525108	19	+	27260156	LNCAPCLONEFGC	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.6090975501593706	[510]	[564,660,884,744]	8	hSpCas9	negative selection	7680281
7527915	7527938	19	-	27260156	LNCAPCLONEFGC	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	-0.34709487630105806	[517]	[415,399,379,277]	-5	hSpCas9	negative selection	7680282
7527888	7527911	19	-	27260156	LNCAPCLONEFGC	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.33711764128300836	[258]	[121,233,105,266]	-5	hSpCas9	negative selection	7680283
7525084	7525107	19	-	27260156	PANC0327	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	-0.013499526081486746	[892]	[485,650,876,1121]	0	hSpCas9	negative selection	7737274
7526766	7526789	19	+	27260156	PANC0327	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	1.1148239008140508	[219]	[456,336,562,349]	9	hSpCas9	negative selection	7737275
7526791	7526814	19	+	27260156	PANC0327	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.34094089693882856	[852]	[750,390,590,698]	-5	hSpCas9	negative selection	7737276
7525085	7525108	19	+	27260156	PANC0327	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.779049883251754	[510]	[727,945,837,577]	9	hSpCas9	negative selection	7801532
7527915	7527938	19	-	27260156	PANC0327	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.1068997818677519	[517]	[515,306,548,635]	1	hSpCas9	negative selection	7801533
7527888	7527911	19	-	27260156	PANC0327	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.5273287530515931	[258]	[230,594,265,191]	7	hSpCas9	negative selection	7801534
7525084	7525107	19	-	27260156	NCIH2009	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.3368522143573134	[892]	[1795,1312,1663]	4	hSpCas9	negative selection	7858525
7526766	7526789	19	+	27260156	NCIH2009	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.565869552165389	[219]	[706,401,305]	7	hSpCas9	negative selection	7858526
7526791	7526814	19	+	27260156	NCIH2009	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	0.08586769136411032	[852]	[1367,1199,1245]	1	hSpCas9	negative selection	7858527
7525085	7525108	19	+	27260156	NCIH2009	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.2486827337472057	[510]	[1309,825,498]	3	hSpCas9	negative selection	7922783
7527915	7527938	19	-	27260156	NCIH2009	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.12276850227544384	[517]	[1111,607,709]	1	hSpCas9	negative selection	7922784
7527888	7527911	19	-	27260156	NCIH2009	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.9967955144606826	[258]	[132,133,267]	-8	hSpCas9	negative selection	7922785
7525084	7525107	19	-	27260156	NCIH1373	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	-0.18636369544393516	[892]	[774,630,664,392]	-2	hSpCas9	negative selection	7979776
7526766	7526789	19	+	27260156	NCIH1373	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.5861666360878486	[219]	[254,283,466,122]	6	hSpCas9	negative selection	7979777
7526791	7526814	19	+	27260156	NCIH1373	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.361137133053445	[852]	[1299,370,541,236]	-4	hSpCas9	negative selection	7979778
7525085	7525108	19	+	27260156	NCIH1373	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.6733239098571496	[510]	[766,779,1009,286]	6	hSpCas9	negative selection	8044034
7527915	7527938	19	-	27260156	NCIH1373	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	-0.6807879376831031	[517]	[304,226,442,126]	-6	hSpCas9	negative selection	8044035
7527888	7527911	19	-	27260156	NCIH1373	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.7634078630021743	[258]	[104,245,219,22]	-6	hSpCas9	negative selection	8044036
7525084	7525107	19	-	27260156	PATU8902	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.09859577498215133	[892]	[1118,1504,1049,1770]	1	hSpCas9	negative selection	8101027
7526766	7526789	19	+	27260156	PATU8902	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.5337599022797217	[219]	[492,358,345,617]	5	hSpCas9	negative selection	8101028
7526791	7526814	19	+	27260156	PATU8902	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.7401829076794687	[852]	[620,1087,585,560]	-6	hSpCas9	negative selection	8101029
7525085	7525108	19	+	27260156	PATU8902	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.6813842672599488	[510]	[1533,784,592,1866]	7	hSpCas9	negative selection	8165285
7527915	7527938	19	-	27260156	PATU8902	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	-0.3279129782759809	[517]	[583,559,150,1181]	-3	hSpCas9	negative selection	8165286
7527888	7527911	19	-	27260156	PATU8902	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-1.096819240670854	[258]	[211,113,65,325]	-7	hSpCas9	negative selection	8165287
7525084	7525107	19	-	27260156	PANC1	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.12202882567405426	[892]	[719,1020,880,756]	2	hSpCas9	negative selection	8222278
7526766	7526789	19	+	27260156	PANC1	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.3868239873893837	[219]	[289,243,186,258]	6	hSpCas9	negative selection	8222279
7526791	7526814	19	+	27260156	PANC1	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.30814912834552854	[852]	[831,785,454,356]	-5	hSpCas9	negative selection	8222280
7525085	7525108	19	+	27260156	PANC1	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.3342685075698014	[510]	[632,609,536,450]	5	hSpCas9	negative selection	8286536
7527915	7527938	19	-	27260156	PANC1	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	-0.1387930776048883	[517]	[426,373,444,363]	-2	hSpCas9	negative selection	8286537
7527888	7527911	19	-	27260156	PANC1	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.24587778761172774	[258]	[215,157,241,133]	-4	hSpCas9	negative selection	8286538
7525084	7525107	19	-	27260156	PANC0813	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.27718381992002517	[892]	[1486,886,1413,1312]	4	hSpCas9	negative selection	8343529
7526766	7526789	19	+	27260156	PANC0813	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.1153317830233278	[219]	[306,190,427,200]	2	hSpCas9	negative selection	8343530
7526791	7526814	19	+	27260156	PANC0813	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.3682954160424192	[852]	[758,858,610,866]	-5	hSpCas9	negative selection	8343531
7525085	7525108	19	+	27260156	PANC0813	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.3948510089023506	[510]	[1047,653,841,643]	6	hSpCas9	negative selection	8407787
7527915	7527938	19	-	27260156	PANC0813	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	-0.0747684925153214	[517]	[684,488,466,672]	-1	hSpCas9	negative selection	8407788
7527888	7527911	19	-	27260156	PANC0813	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.5099397063951832	[258]	[168,235,176,264]	-6	hSpCas9	negative selection	8407789
7525084	7525107	19	-	27260156	RDES	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.1400617407951048	[892]	[900,974,1403,1316]	2	hSpCas9	negative selection	8464780
7526766	7526789	19	+	27260156	RDES	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.45382686143974715	[219]	[275,289,350,503]	7	hSpCas9	negative selection	8464781
7526791	7526814	19	+	27260156	RDES	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.12635032352195674	[852]	[850,874,919,937]	-2	hSpCas9	negative selection	8464782
7525085	7525108	19	+	27260156	RDES	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.5562826472217351	[510]	[616,812,942,1166]	8	hSpCas9	negative selection	8529038
7527915	7527938	19	-	27260156	RDES	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.080303074355742	[517]	[534,476,698,862]	1	hSpCas9	negative selection	8529039
7527888	7527911	19	-	27260156	RDES	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.09222162064789763	[258]	[272,201,297,356]	-1	hSpCas9	negative selection	8529040
7525084	7525107	19	-	27260156	PC3	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.37839595301672424	[892]	[637,1212,2117,1156]	7	hSpCas9	negative selection	8586031
7526766	7526789	19	+	27260156	PC3	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.30797247552812135	[219]	[121,263,581,285]	6	hSpCas9	negative selection	8586032
7526791	7526814	19	+	27260156	PC3	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	0.04909019665766601	[852]	[516,684,1872,923]	1	hSpCas9	negative selection	8586033
7525085	7525108	19	+	27260156	PC3	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.23308173111028	[510]	[436,462,1047,635]	5	hSpCas9	negative selection	8650289
7527915	7527938	19	-	27260156	PC3	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.15436495383562182	[517]	[260,463,842,953]	3	hSpCas9	negative selection	8650290
7527888	7527911	19	-	27260156	PC3	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.5625073436184629	[258]	[73,254,358,106]	-8	hSpCas9	negative selection	8650291
7525084	7525107	19	-	27260156	PATU8988T	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.22526283172412453	[892]	[1051,948,1028,997]	4	hSpCas9	negative selection	8707282
7526766	7526789	19	+	27260156	PATU8988T	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.4253721595591907	[219]	[330,401,183,232]	7	hSpCas9	negative selection	8707283
7526791	7526814	19	+	27260156	PATU8988T	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.16123895069159933	[852]	[636,802,618,910]	-3	hSpCas9	negative selection	8707284
7525085	7525108	19	+	27260156	PATU8988T	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.288534056241485	[510]	[551,633,516,722]	5	hSpCas9	negative selection	8771540
7527915	7527938	19	-	27260156	PATU8988T	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	-0.2098829420170194	[517]	[438,619,375,303]	-4	hSpCas9	negative selection	8771541
7527888	7527911	19	-	27260156	PATU8988T	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.45239509232855757	[258]	[141,183,164,245]	-6	hSpCas9	negative selection	8771542
7525084	7525107	19	-	27260156	T47D	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.19924456247182376	[892]	[1340,1179,1087,1170]	4	hSpCas9	negative selection	8828533
7526766	7526789	19	+	27260156	T47D	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.18290167369401256	[219]	[359,240,266,300]	4	hSpCas9	negative selection	8828534
7526791	7526814	19	+	27260156	T47D	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.22034410422041972	[852]	[818,746,946,907]	-5	hSpCas9	negative selection	8828535
7525085	7525108	19	+	27260156	T47D	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.3408831767237077	[510]	[736,682,750,853]	7	hSpCas9	negative selection	8892791
7527915	7527938	19	-	27260156	T47D	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.15212408744832762	[517]	[674,603,692,716]	3	hSpCas9	negative selection	8892792
7527888	7527911	19	-	27260156	T47D	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.08304448538631215	[258]	[318,250,294,276]	-2	hSpCas9	negative selection	8892793
7525084	7525107	19	-	27260156	SU8686	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.1804197020998901	[892]	[905,865,1129,1161]	3	hSpCas9	negative selection	8949784
7526766	7526789	19	+	27260156	SU8686	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.12442169706615591	[219]	[325,217,110,291]	2	hSpCas9	negative selection	8949785
7526791	7526814	19	+	27260156	SU8686	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.5173708851287717	[852]	[465,585,646,692]	-7	hSpCas9	negative selection	8949786
7525085	7525108	19	+	27260156	SU8686	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.49355222804271937	[510]	[552,518,1034,808]	8	hSpCas9	negative selection	9014042
7527915	7527938	19	-	27260156	SU8686	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	-0.08910010514802283	[517]	[426,442,527,553]	-1	hSpCas9	negative selection	9014043
7527888	7527911	19	-	27260156	SU8686	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.4688189978694708	[258]	[105,208,182,260]	-6	hSpCas9	negative selection	9014044
7525084	7525107	19	-	27260156	SKES1	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.07154036194980529	[892]	[1208,928,798,846]	1	hSpCas9	negative selection	9071035
7526766	7526789	19	+	27260156	SKES1	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	-0.07094492002200425	[219]	[151,156,215,284]	-1	hSpCas9	negative selection	9071036
7526791	7526814	19	+	27260156	SKES1	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.33758864598426574	[852]	[757,853,614,512]	-6	hSpCas9	negative selection	9071037
7525085	7525108	19	+	27260156	SKES1	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.2644857480544748	[510]	[685,835,573,408]	5	hSpCas9	negative selection	9135293
7527915	7527938	19	-	27260156	SKES1	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.25858508623580845	[517]	[523,823,604,534]	5	hSpCas9	negative selection	9135294
7527888	7527911	19	-	27260156	SKES1	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.15686602437185937	[258]	[266,394,333,175]	3	hSpCas9	negative selection	9135295
7525084	7525107	19	-	27260156	TOV112D	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.023255098725206258	[892]	[937,1124,797,830]	0	hSpCas9	negative selection	9192286
7526766	7526789	19	+	27260156	TOV112D	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.09223895863736842	[219]	[222,309,273,151]	1	hSpCas9	negative selection	9192287
7526791	7526814	19	+	27260156	TOV112D	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.2527159354459888	[852]	[767,754,617,738]	-5	hSpCas9	negative selection	9192288
7525085	7525108	19	+	27260156	TOV112D	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.6269518977093027	[510]	[686,778,796,882]	9	hSpCas9	negative selection	9256544
7527915	7527938	19	-	27260156	TOV112D	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	-0.13749826106777466	[517]	[473,758,407,319]	-3	hSpCas9	negative selection	9256545
7527888	7527911	19	-	27260156	TOV112D	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.5283976787918625	[258]	[109,173,255,171]	-8	hSpCas9	negative selection	9256546
7525084	7525107	19	-	27260156	TC71	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.1145456944862755	[892]	[1000,968,1014,1169]	3	hSpCas9	negative selection	9313537
7526766	7526789	19	+	27260156	TC71	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.12677599101802173	[219]	[309,206,242,269]	3	hSpCas9	negative selection	9313538
7526791	7526814	19	+	27260156	TC71	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.16805184604724455	[852]	[954,799,788,701]	-4	hSpCas9	negative selection	9313539
7525085	7525108	19	+	27260156	TC71	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.1698569452792448	[510]	[621,606,544,697]	4	hSpCas9	negative selection	9377795
7527915	7527938	19	-	27260156	TC71	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.33119350273818227	[517]	[698,635,640,827]	7	hSpCas9	negative selection	9377796
7527888	7527911	19	-	27260156	TC71	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-0.24982287439997442	[258]	[180,194,234,329]	-6	hSpCas9	negative selection	9377797
7525084	7525107	19	-	27260156	TC32	viability	CTTGGCTCGAAACTTGTCGCAGG	MCOLN1	ENSG00000090674	0.31233738871937344	[892]	[925,796,1507,1064]	5	hSpCas9	negative selection	9434788
7526766	7526789	19	+	27260156	TC32	viability	GGCGTTGCCTGACGTGTCACTGG	MCOLN1	ENSG00000090674	0.895206183235979	[219]	[341,383,417,379]	9	hSpCas9	negative selection	9434789
7526791	7526814	19	+	27260156	TC32	viability	CGGTATGCGTATGTCCGTGGTGG	MCOLN1	ENSG00000090674	-0.4484757025354146	[852]	[542,311,990,655]	-7	hSpCas9	negative selection	9434790
7525085	7525108	19	+	27260156	TC32	viability	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.49444949526618187	[510]	[504,485,894,927]	8	hSpCas9	negative selection	9499046
7527915	7527938	19	-	27260156	TC32	viability	CCGGGATCTCATTATTGATGAGG	MCOLN1	ENSG00000090674	0.08156771866891493	[517]	[448,237,876,653]	1	hSpCas9	negative selection	9499047
7527888	7527911	19	-	27260156	TC32	viability	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.343751809460194	[258]	[273,276,409,287]	6	hSpCas9	negative selection	9499048
7525085	7525108	19	+	27869803	HPAFII	viability after 27 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.5081859749061648	[612]	[393,511,NaN]	4	hSpCas9	negative selection	9570622
7526494	7526517	19	-	27869803	HPAFII	viability after 27 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-0.7436050651516941	[151]	[44,49,NaN]	-5	hSpCas9	negative selection	9570623
7526883	7526906	19	-	27869803	HPAFII	viability after 27 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	1.1850230119651437	[187]	[269,186,NaN]	8	hSpCas9	negative selection	9570624
7527888	7527911	19	-	27869803	HPAFII	viability after 27 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-2.928510134225583	[103]	[4,8,NaN]	-9	hSpCas9	negative selection	9570625
7528240	7528263	19	-	27869803	HPAFII	viability after 27 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.5956664989451294	[256]	[219,190,NaN]	5	hSpCas9	negative selection	9570626
7528610	7528633	19	-	27869803	HPAFII	viability after 27 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.24344254856371184	[376]	[328,155,NaN]	2	hSpCas9	negative selection	9570627
7525085	7525108	19	+	27869803	HPAFII	viability after 15 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.3640556146618146	[612]	[813,868,NaN]	4	hSpCas9	negative selection	9653071
7526494	7526517	19	-	27869803	HPAFII	viability after 15 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	0.5012699715632593	[151]	[348,157,NaN]	6	hSpCas9	negative selection	9653072
7526883	7526906	19	-	27869803	HPAFII	viability after 15 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	1.041282118127885	[187]	[540,337,NaN]	9	hSpCas9	negative selection	9653073
7527888	7527911	19	-	27869803	HPAFII	viability after 15 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-1.8659253739104003	[103]	[5,45,NaN]	-9	hSpCas9	negative selection	9653074
7528240	7528263	19	-	27869803	HPAFII	viability after 15 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.6245781657937199	[256]	[349,472,NaN]	7	hSpCas9	negative selection	9653075
7528610	7528633	19	-	27869803	HPAFII	viability after 15 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.22858355593317603	[376]	[491,463,NaN]	2	hSpCas9	negative selection	9653076
7525085	7525108	19	+	27869803	ASPC1	viability after 36 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.16937660888614725	[1638]	[590,459,818]	1	hSpCas9	negative selection	9735520
7526494	7526517	19	-	27869803	ASPC1	viability after 36 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-1.333691478205489	[398]	[47,25,82]	-8	hSpCas9	negative selection	9735521
7526883	7526906	19	-	27869803	ASPC1	viability after 36 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	-0.2472686424224687	[670]	[225,291,99]	-3	hSpCas9	negative selection	9735522
7527888	7527911	19	-	27869803	ASPC1	viability after 36 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-1.038237202406012	[240]	[0,115,8]	-7	hSpCas9	negative selection	9735523
7528240	7528263	19	-	27869803	ASPC1	viability after 36 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.7311107608656036	[710]	[488,282,455]	7	hSpCas9	negative selection	9735524
7528610	7528633	19	-	27869803	ASPC1	viability after 36 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.25755314662305406	[852]	[608,313,207]	2	hSpCas9	negative selection	9735525
7525085	7525108	19	+	27869803	PATU8988S	viability after 35 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	-0.04574759439708309	[1308]	[398,622,NaN]	0	hSpCas9	negative selection	9817969
7526494	7526517	19	-	27869803	PATU8988S	viability after 35 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	1.0463667218273922	[322]	[344,191,NaN]	9	hSpCas9	negative selection	9817970
7526883	7526906	19	-	27869803	PATU8988S	viability after 35 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	0.7493209958027361	[402]	[421,122,NaN]	7	hSpCas9	negative selection	9817971
7527888	7527911	19	-	27869803	PATU8988S	viability after 35 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.5653137329506781	[161]	[115,76,NaN]	6	hSpCas9	negative selection	9817972
7528240	7528263	19	-	27869803	PATU8988S	viability after 35 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.40947470693156823	[718]	[435,332,NaN]	4	hSpCas9	negative selection	9817973
7528610	7528633	19	-	27869803	PATU8988S	viability after 35 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.4539745252039451	[644]	[504,205,NaN]	5	hSpCas9	negative selection	9817974
7525085	7525108	19	+	27869803	PATU8988S	viability after 31 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.15917703469039113	[1308]	[394,821,NaN]	2	hSpCas9	negative selection	9900418
7526494	7526517	19	-	27869803	PATU8988S	viability after 31 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	0.3623670072251386	[322]	[209,108,NaN]	4	hSpCas9	negative selection	9900419
7526883	7526906	19	-	27869803	PATU8988S	viability after 31 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	0.12876989082469809	[402]	[253,75,NaN]	1	hSpCas9	negative selection	9900420
7527888	7527911	19	-	27869803	PATU8988S	viability after 31 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	0.6177241112979488	[161]	[99,97,NaN]	7	hSpCas9	negative selection	9900421
7528240	7528263	19	-	27869803	PATU8988S	viability after 31 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.1423863077568342	[718]	[293,344,NaN]	1	hSpCas9	negative selection	9900422
7528610	7528633	19	-	27869803	PATU8988S	viability after 31 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.445177088118216	[644]	[343,357,NaN]	5	hSpCas9	negative selection	9900423
7525085	7525108	19	+	27869803	HPAFII	viability after 35 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.7274705189554878	[612]	[272,784,NaN]	5	hSpCas9	negative selection	9982867
7526494	7526517	19	-	27869803	HPAFII	viability after 35 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-0.31403594296281745	[151]	[91,27,NaN]	-2	hSpCas9	negative selection	9982868
7526883	7526906	19	-	27869803	HPAFII	viability after 35 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	1.183178979497599	[187]	[217,213,NaN]	7	hSpCas9	negative selection	9982869
7527888	7527911	19	-	27869803	HPAFII	viability after 35 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-1.6514961903881655	[103]	[4,29,NaN]	-7	hSpCas9	negative selection	9982870
7528240	7528263	19	-	27869803	HPAFII	viability after 35 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.6022161552192958	[256]	[149,250,NaN]	4	hSpCas9	negative selection	9982871
7528610	7528633	19	-	27869803	HPAFII	viability after 35 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.5049117960050619	[376]	[283,255,NaN]	3	hSpCas9	negative selection	9982872
7525085	7525108	19	+	27869803	HPAFII	viability after 31 days	CTGCGACAAGTTTCGAGCCAAGG	MCOLN1	ENSG00000090674	0.51142209124869	[612]	[353,638,NaN]	4	hSpCas9	negative selection	10065316
7526494	7526517	19	-	27869803	HPAFII	viability after 31 days	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-0.5268569831796464	[151]	[74,41,NaN]	-4	hSpCas9	negative selection	10065317
7526883	7526906	19	-	27869803	HPAFII	viability after 31 days	TGTCAAATGTGTCGTTGGCCGGG	MCOLN1	ENSG00000090674	0.8803939775943257	[187]	[176,212,NaN]	6	hSpCas9	negative selection	10065318
7527888	7527911	19	-	27869803	HPAFII	viability after 31 days	GGAGGTTAATGGTCTTCAGCCGG	MCOLN1	ENSG00000090674	-1.0083770111146477	[103]	[6,52,NaN]	-6	hSpCas9	negative selection	10065319
7528240	7528263	19	-	27869803	HPAFII	viability after 31 days	CTCACCGTGCTGGAAGACACTGG	MCOLN1	ENSG00000090674	0.6101364926045285	[256]	[178,264,NaN]	4	hSpCas9	negative selection	10065320
7528610	7528633	19	-	27869803	HPAFII	viability after 31 days	CCACCACGTCAAACAGGAGCCGG	MCOLN1	ENSG00000090674	0.426510720440339	[376]	[269,299,NaN]	3	hSpCas9	negative selection	10065321
7526494	7526517	19	-	28162770	P31FUJ	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-0.1838926039334322	[115]	[119]	-2	hSpCas9	negative selection	10190270
7528642	7528665	19	-	28162770	P31FUJ	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-3.6922338230516756	[10]	[0]	-9	hSpCas9	negative selection	10190271
7525133	7525156	19	+	28162770	P31FUJ	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-2.111947809539993	[308]	[83]	-8	hSpCas9	negative selection	10190272
7528661	7528684	19	-	28162770	P31FUJ	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-3.6020360140800975	[247]	[23]	-9	hSpCas9	negative selection	10190273
7528949	7528972	19	+	28162770	P31FUJ	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.17264924603526716	[150]	[199]	1	hSpCas9	negative selection	10190274
7529130	7529153	19	-	28162770	P31FUJ	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	-1.554730299301741	[54]	[21]	-7	hSpCas9	negative selection	10190275
7522744	7522767	19	+	28162770	P31FUJ	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	0.16688104798742898	[613]	[809]	1	hSpCas9	negative selection	10190276
7524986	7525009	19	-	28162770	P31FUJ	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	0.17001934515482597	[592]	[783]	1	hSpCas9	negative selection	10190277
7525049	7525072	19	-	28162770	P31FUJ	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	0.5524589467926085	[234]	[404]	6	hSpCas9	negative selection	10190278
7527560	7527583	19	-	28162770	P31FUJ	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	0.4802854877408511	[462]	[758]	5	hSpCas9	negative selection	10190279
7526494	7526517	19	-	28162770	TF1	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10359636
7528642	7528665	19	-	28162770	TF1	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10359637
7525133	7525156	19	+	28162770	TF1	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10359638
7528661	7528684	19	-	28162770	TF1	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10359639
7528949	7528972	19	+	28162770	TF1	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	NaN	[NaN]	[261]	1	hSpCas9	negative selection	10359640
7529130	7529153	19	-	28162770	TF1	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10359641
7522744	7522767	19	+	28162770	TF1	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	NaN	[NaN]	[530]	1	hSpCas9	negative selection	10359642
7524986	7525009	19	-	28162770	TF1	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	NaN	[NaN]	[351]	1	hSpCas9	negative selection	10359643
7525049	7525072	19	-	28162770	TF1	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	NaN	[NaN]	[343]	1	hSpCas9	negative selection	10359644
7527560	7527583	19	-	28162770	TF1	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	NaN	[NaN]	[325]	1	hSpCas9	negative selection	10359645
7526494	7526517	19	-	28162770	SKM1	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	0.277533975528909	[20]	[44]	2	hSpCas9	negative selection	10529002
7528642	7528665	19	-	28162770	SKM1	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-2.8220016980220053	[3]	[0]	-9	hSpCas9	negative selection	10529003
7525133	7525156	19	+	28162770	SKM1	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-1.4449320489421822	[76]	[49]	-7	hSpCas9	negative selection	10529004
7528661	7528684	19	-	28162770	SKM1	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-2.6078768926691582	[99]	[28]	-9	hSpCas9	negative selection	10529005
7528949	7528972	19	+	28162770	SKM1	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.3557854211932775	[60]	[137]	3	hSpCas9	negative selection	10529006
7529130	7529153	19	-	28162770	SKM1	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	-0.38904229074589947	[19]	[26]	-3	hSpCas9	negative selection	10529007
7522744	7522767	19	+	28162770	SKM1	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	0.04179391837968305	[110]	[201]	0	hSpCas9	negative selection	10529008
7524986	7525009	19	-	28162770	SKM1	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	0.19454947824184243	[129]	[262]	2	hSpCas9	negative selection	10529009
7525049	7525072	19	-	28162770	SKM1	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	1.0378206439297342	[53]	[195]	8	hSpCas9	negative selection	10529010
7527560	7527583	19	-	28162770	SKM1	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	-0.006084762460977444	[95]	[168]	0	hSpCas9	negative selection	10529011
7526494	7526517	19	-	28162770	SKM1	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	0.277533975528909	[20]	[44]	2	hSpCas9	negative selection	10698368
7528642	7528665	19	-	28162770	SKM1	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-2.8220016980220053	[3]	[0]	-9	hSpCas9	negative selection	10698369
7525133	7525156	19	+	28162770	SKM1	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-1.4449320489421822	[76]	[49]	-7	hSpCas9	negative selection	10698370
7528661	7528684	19	-	28162770	SKM1	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-2.6078768926691582	[99]	[28]	-9	hSpCas9	negative selection	10698371
7528949	7528972	19	+	28162770	SKM1	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.3557854211932775	[60]	[137]	3	hSpCas9	negative selection	10698372
7529130	7529153	19	-	28162770	SKM1	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	-0.38904229074589947	[19]	[26]	-3	hSpCas9	negative selection	10698373
7522744	7522767	19	+	28162770	SKM1	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	0.04179391837968305	[110]	[201]	0	hSpCas9	negative selection	10698374
7524986	7525009	19	-	28162770	SKM1	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	0.19454947824184243	[129]	[262]	2	hSpCas9	negative selection	10698375
7525049	7525072	19	-	28162770	SKM1	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	1.0378206439297342	[53]	[195]	8	hSpCas9	negative selection	10698376
7527560	7527583	19	-	28162770	SKM1	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	-0.006084762460977444	[95]	[168]	0	hSpCas9	negative selection	10698377
7526494	7526517	19	-	28162770	PL21	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-1.1422525829577577	[70]	[13]	-6	hSpCas9	negative selection	10867734
7528642	7528665	19	-	28162770	PL21	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-2.7067509811191988	[14]	[0]	-9	hSpCas9	negative selection	10867735
7525133	7525156	19	+	28162770	PL21	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-0.733309192602074	[232]	[60]	-5	hSpCas9	negative selection	10867736
7528661	7528684	19	-	28162770	PL21	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-1.7792206194516433	[346]	[43]	-8	hSpCas9	negative selection	10867737
7528949	7528972	19	+	28162770	PL21	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	-0.8209220010385098	[206]	[50]	-5	hSpCas9	negative selection	10867738
7529130	7529153	19	-	28162770	PL21	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	-2.2755938164770777	[88]	[7]	-8	hSpCas9	negative selection	10867739
7522744	7522767	19	+	28162770	PL21	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	-0.2293053086105491	[368]	[136]	-2	hSpCas9	negative selection	10867740
7524986	7525009	19	-	28162770	PL21	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	0.23184847421665844	[404]	[206]	2	hSpCas9	negative selection	10867741
7525049	7525072	19	-	28162770	PL21	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	0.7748337797566492	[187]	[139]	6	hSpCas9	negative selection	10867742
7527560	7527583	19	-	28162770	PL21	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	0.7385595292734461	[335]	[243]	6	hSpCas9	negative selection	10867743
7526494	7526517	19	-	28162770	P31FUJ	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-0.1838926039334322	[115]	[119]	-2	hSpCas9	negative selection	11037100
7528642	7528665	19	-	28162770	P31FUJ	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-3.6922338230516756	[10]	[0]	-9	hSpCas9	negative selection	11037101
7525133	7525156	19	+	28162770	P31FUJ	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-2.111947809539993	[308]	[83]	-8	hSpCas9	negative selection	11037102
7528661	7528684	19	-	28162770	P31FUJ	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-3.6020360140800975	[247]	[23]	-9	hSpCas9	negative selection	11037103
7528949	7528972	19	+	28162770	P31FUJ	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.17264924603526716	[150]	[199]	1	hSpCas9	negative selection	11037104
7529130	7529153	19	-	28162770	P31FUJ	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	-1.554730299301741	[54]	[21]	-7	hSpCas9	negative selection	11037105
7522744	7522767	19	+	28162770	P31FUJ	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	0.16688104798742898	[613]	[809]	1	hSpCas9	negative selection	11037106
7524986	7525009	19	-	28162770	P31FUJ	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	0.17001934515482597	[592]	[783]	1	hSpCas9	negative selection	11037107
7525049	7525072	19	-	28162770	P31FUJ	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	0.5524589467926085	[234]	[404]	6	hSpCas9	negative selection	11037108
7527560	7527583	19	-	28162770	P31FUJ	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	0.4802854877408511	[462]	[758]	5	hSpCas9	negative selection	11037109
7526494	7526517	19	-	28162770	OCIAML5	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-0.5486744274140622	[46]	[57]	-4	hSpCas9	negative selection	11206466
7528642	7528665	19	-	28162770	OCIAML5	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-3.852066570863997	[7]	[0]	-9	hSpCas9	negative selection	11206467
7525133	7525156	19	+	28162770	OCIAML5	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-0.8399937385634219	[118]	[119]	-5	hSpCas9	negative selection	11206468
7528661	7528684	19	-	28162770	OCIAML5	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-2.3477617334880656	[140]	[49]	-8	hSpCas9	negative selection	11206469
7528949	7528972	19	+	28162770	OCIAML5	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.6026733524485781	[111]	[306]	5	hSpCas9	negative selection	11206470
7529130	7529153	19	-	28162770	OCIAML5	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	-0.7112040350241475	[38]	[42]	-5	hSpCas9	negative selection	11206471
7522744	7522767	19	+	28162770	OCIAML5	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	-0.9862519182583941	[303]	[276]	-6	hSpCas9	negative selection	11206472
7524986	7525009	19	-	28162770	OCIAML5	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	-0.5775281929117526	[228]	[276]	-4	hSpCas9	negative selection	11206473
7525049	7525072	19	-	28162770	OCIAML5	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	-0.21819446966189454	[144]	[224]	-1	hSpCas9	negative selection	11206474
7527560	7527583	19	-	28162770	OCIAML5	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	0.22144209887157984	[219]	[462]	1	hSpCas9	negative selection	11206475
7526494	7526517	19	-	28162770	EOL1	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-0.7774541503408409	[230]	[70]	-5	hSpCas9	negative selection	11375832
7528642	7528665	19	-	28162770	EOL1	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-3.162915069679805	[16]	[0]	-9	hSpCas9	negative selection	11375833
7525133	7525156	19	+	28162770	EOL1	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-1.973297684434977	[476]	[63]	-8	hSpCas9	negative selection	11375834
7528661	7528684	19	-	28162770	EOL1	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-1.9617954466338983	[487]	[65]	-8	hSpCas9	negative selection	11375835
7528949	7528972	19	+	28162770	EOL1	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.6670063640975012	[366]	[306]	6	hSpCas9	negative selection	11375836
7529130	7529153	19	-	28162770	EOL1	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	-0.99431546570406	[120]	[31]	-6	hSpCas9	negative selection	11375837
7522744	7522767	19	+	28162770	EOL1	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	-0.4684115622492447	[561]	[213]	-3	hSpCas9	negative selection	11375838
7524986	7525009	19	-	28162770	EOL1	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	0.22322522114841759	[612]	[376]	2	hSpCas9	negative selection	11375839
7525049	7525072	19	-	28162770	EOL1	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	-0.6655216195837104	[282]	[93]	-5	hSpCas9	negative selection	11375840
7527560	7527583	19	-	28162770	EOL1	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	0.22597755614133874	[481]	[296]	2	hSpCas9	negative selection	11375841
7526494	7526517	19	-	28162770	MOLM13	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-0.3206065132617094	[151]	[87]	-2	hSpCas9	negative selection	11545198
7528642	7528665	19	-	28162770	MOLM13	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-4.232550336596514	[25]	[0]	-9	hSpCas9	negative selection	11545199
7525133	7525156	19	+	28162770	MOLM13	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-1.650848165038944	[442]	[101]	-7	hSpCas9	negative selection	11545200
7528661	7528684	19	-	28162770	MOLM13	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-5.1283003745998315	[386]	[7]	-9	hSpCas9	negative selection	11545201
7528949	7528972	19	+	28162770	MOLM13	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	1.2795963281418898	[330]	[580]	8	hSpCas9	negative selection	11545202
7529130	7529153	19	-	28162770	MOLM13	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	-0.15474353714263223	[96]	[62]	-1	hSpCas9	negative selection	11545203
7522744	7522767	19	+	28162770	MOLM13	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	-0.28329007184132815	[509]	[302]	-2	hSpCas9	negative selection	11545204
7524986	7525009	19	-	28162770	MOLM13	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	-0.9860415926964219	[588]	[214]	-5	hSpCas9	negative selection	11545205
7525049	7525072	19	-	28162770	MOLM13	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	-1.5093905419553377	[314]	[79]	-6	hSpCas9	negative selection	11545206
7527560	7527583	19	-	28162770	MOLM13	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	-0.8011437649106582	[481]	[199]	-4	hSpCas9	negative selection	11545207
7526494	7526517	19	-	28162770	HEL	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	1.3594912052770542	[114]	[188]	9	hSpCas9	negative selection	11714564
7528642	7528665	19	-	28162770	HEL	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-3.0577008861407355	[12]	[0]	-8	hSpCas9	negative selection	11714565
7525133	7525156	19	+	28162770	HEL	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-2.2898166470015084	[396]	[51]	-8	hSpCas9	negative selection	11714566
7528661	7528684	19	-	28162770	HEL	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-1.5681579504982617	[374]	[80]	-7	hSpCas9	negative selection	11714567
7528949	7528972	19	+	28162770	HEL	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.8740643781068128	[298]	[350]	7	hSpCas9	negative selection	11714568
7529130	7529153	19	-	28162770	HEL	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	-1.0991930150591984	[96]	[28]	-6	hSpCas9	negative selection	11714569
7522744	7522767	19	+	28162770	HEL	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	0.04930481521174901	[426]	[282]	0	hSpCas9	negative selection	11714570
7524986	7525009	19	-	28162770	HEL	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	-0.6592048884328507	[465]	[188]	-4	hSpCas9	negative selection	11714571
7525049	7525072	19	-	28162770	HEL	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	-0.3689429730472782	[247]	[122]	-3	hSpCas9	negative selection	11714572
7527560	7527583	19	-	28162770	HEL	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	1.0811526693685711	[351]	[476]	8	hSpCas9	negative selection	11714573
7526494	7526517	19	-	28162770	MV411	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-0.2138936007700033	[94]	[68]	-2	hSpCas9	negative selection	11883930
7528642	7528665	19	-	28162770	MV411	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-3.5599173712748287	[27]	[1]	-9	hSpCas9	negative selection	11883931
7525133	7525156	19	+	28162770	MV411	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-2.2172307162206693	[275]	[49]	-8	hSpCas9	negative selection	11883932
7528661	7528684	19	-	28162770	MV411	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-1.9127394741079748	[294]	[65]	-8	hSpCas9	negative selection	11883933
7528949	7528972	19	+	28162770	MV411	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.19497013088863954	[195]	[188]	1	hSpCas9	negative selection	11883934
7529130	7529153	19	-	28162770	MV411	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	1.4369153496464884	[56]	[129]	9	hSpCas9	negative selection	11883935
7522744	7522767	19	+	28162770	MV411	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	0.12605831196938377	[346]	[318]	1	hSpCas9	negative selection	11883936
7524986	7525009	19	-	28162770	MV411	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	-1.2427271953941297	[426]	[151]	-7	hSpCas9	negative selection	11883937
7525049	7525072	19	-	28162770	MV411	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	0.6291164531151882	[174]	[227]	5	hSpCas9	negative selection	11883938
7527560	7527583	19	-	28162770	MV411	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	0.07497035477800962	[354]	[314]	0	hSpCas9	negative selection	11883939
7526494	7526517	19	-	28162770	MONOMAC1	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	0.2531288756228919	[70]	[96]	2	hSpCas9	negative selection	12053296
7528642	7528665	19	-	28162770	MONOMAC1	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-3.589354269838314	[20]	[1]	-9	hSpCas9	negative selection	12053297
7525133	7525156	19	+	28162770	MONOMAC1	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-0.8250680696725958	[135]	[87]	-6	hSpCas9	negative selection	12053298
7528661	7528684	19	-	28162770	MONOMAC1	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-1.1145746868675808	[169]	[89]	-7	hSpCas9	negative selection	12053299
7528949	7528972	19	+	28162770	MONOMAC1	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.9296349564288746	[157]	[344]	8	hSpCas9	negative selection	12053300
7529130	7529153	19	-	28162770	MONOMAC1	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	-0.07150596497569484	[43]	[47]	0	hSpCas9	negative selection	12053301
7522744	7522767	19	+	28162770	MONOMAC1	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	0.36117292605591733	[253]	[373]	3	hSpCas9	negative selection	12053302
7524986	7525009	19	-	28162770	MONOMAC1	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	0.012104550779038048	[249]	[288]	0	hSpCas9	negative selection	12053303
7525049	7525072	19	-	28162770	MONOMAC1	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	-0.451850746088379	[104]	[87]	-4	hSpCas9	negative selection	12053304
7527560	7527583	19	-	28162770	MONOMAC1	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	-0.27069388878486267	[220]	[209]	-2	hSpCas9	negative selection	12053305
7526494	7526517	19	-	28162770	OCIAML2	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-0.992582528437517	[27]	[77]	-6	hSpCas9	negative selection	12222662
7528642	7528665	19	-	28162770	OCIAML2	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-4.0555923259633175	[2]	[0]	-9	hSpCas9	negative selection	12222663
7525133	7525156	19	+	28162770	OCIAML2	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-1.2296217257383664	[43]	[103]	-7	hSpCas9	negative selection	12222664
7528661	7528684	19	-	28162770	OCIAML2	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-1.8614197782743276	[58]	[89]	-8	hSpCas9	negative selection	12222665
7528949	7528972	19	+	28162770	OCIAML2	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	-0.05109093372837645	[39]	[213]	0	hSpCas9	negative selection	12222666
7529130	7529153	19	-	28162770	OCIAML2	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	0.2383213927544483	[12]	[84]	2	hSpCas9	negative selection	12222667
7522744	7522767	19	+	28162770	OCIAML2	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	0.011762941838447172	[67]	[379]	0	hSpCas9	negative selection	12222668
7524986	7525009	19	-	28162770	OCIAML2	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	-0.24823740390571314	[74]	[349]	-2	hSpCas9	negative selection	12222669
7525049	7525072	19	-	28162770	OCIAML2	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	-0.20759541940836726	[39]	[191]	-2	hSpCas9	negative selection	12222670
7527560	7527583	19	-	28162770	OCIAML2	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	0.051791209410282146	[54]	[315]	0	hSpCas9	negative selection	12222671
7526494	7526517	19	-	28162770	OCIAML3	viability	GAAGAGGTGTCGGAAGGCGATGG	MCOLN1	ENSG00000090674	-1.153435048938182	[27]	[37]	-7	hSpCas9	negative selection	12392028
7528642	7528665	19	-	28162770	OCIAML3	viability	GAGGAGGAAGGACAGGGAGCAGG	MCOLN1	ENSG00000090674	-4.763932641766475	[8]	[0]	-9	hSpCas9	negative selection	12392029
7525133	7525156	19	+	28162770	OCIAML3	viability	GCAAGTGGTCAAGATCCTGGTGG	MCOLN1	ENSG00000090674	-0.994969954391284	[67]	[102]	-6	hSpCas9	negative selection	12392030
7528661	7528684	19	-	28162770	OCIAML3	viability	GAAGGAGTGAGCGGGCGCAGAGG	MCOLN1	ENSG00000090674	-1.3693013531494689	[88]	[103]	-7	hSpCas9	negative selection	12392031
7528949	7528972	19	+	28162770	OCIAML3	viability	GAAGATCGGCATCGAGGCCAAGG	MCOLN1	ENSG00000090674	0.22068925707460896	[55]	[196]	2	hSpCas9	negative selection	12392032
7529130	7529153	19	-	28162770	OCIAML3	viability	GCAGCGTCGAGGTGCCCAGGAGG	MCOLN1	ENSG00000090674	-2.0534392589614603	[21]	[15]	-8	hSpCas9	negative selection	12392033
7522744	7522767	19	+	28162770	OCIAML3	viability	CCCCAGCATGACAGCCCCGGCGG	MCOLN1	ENSG00000090674	0.17553088763039582	[126]	[432]	1	hSpCas9	negative selection	12392034
7524986	7525009	19	-	28162770	OCIAML3	viability	CCGCCTGGGTCCCATACCCGGGG	MCOLN1	ENSG00000090674	0.21527215865793292	[106]	[374]	2	hSpCas9	negative selection	12392035
7525049	7525072	19	-	28162770	OCIAML3	viability	AGTATTTGAGACGACGGCGAAGG	MCOLN1	ENSG00000090674	0.2849005427584749	[58]	[216]	2	hSpCas9	negative selection	12392036
7527560	7527583	19	-	28162770	OCIAML3	viability	AGAGGGTGAGATCGTCGCTGGGG	MCOLN1	ENSG00000090674	-0.5548370430434856	[108]	[223]	-4	hSpCas9	negative selection	12392037