Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 51102
• Symbol: MECR
• Description: mitochondrial trans-2-enoyl-CoA reductase

DataSource: http://genomecrispr.dkfz.de/#!/results/MECR

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
29206805	29206828	1	+	26472758	Jiyoye	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-0.422899617051814	[79]	[44]	-3	hSpCas9	negative selection	98076
29195960	29195983	1	-	26472758	Jiyoye	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-0.4293258862112471	[199]	[111]	-3	hSpCas9	negative selection	98077
29206778	29206801	1	+	26472758	Jiyoye	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-0.8235585324246104	[635]	[270]	-5	hSpCas9	negative selection	98078
29200555	29200578	1	+	26472758	Jiyoye	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-0.14692615551052213	[184]	[125]	-1	hSpCas9	negative selection	98079
29196192	29196215	1	+	26472758	Jiyoye	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	0.23923074419180182	[90]	[80]	1	hSpCas9	negative selection	98080
29216624	29216647	1	-	26472758	Jiyoye	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	0.18026040147873124	[425]	[363]	1	hSpCas9	negative selection	98081
29203195	29203218	1	-	26472758	Jiyoye	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.5188240370503499	[113]	[59]	-4	hSpCas9	negative selection	98082
29201978	29202001	1	-	26472758	Jiyoye	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-1.0813242797139915	[375]	[133]	-6	hSpCas9	negative selection	98083
29200524	29200547	1	-	26472758	Jiyoye	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	-0.5668294099611819	[54]	[27]	-4	hSpCas9	negative selection	98084
29196232	29196255	1	-	26472758	Jiyoye	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-0.31472276457139087	[126]	[76]	-2	hSpCas9	negative selection	98085
29206805	29206828	1	+	26472758	KBM7	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-1.3058640225815001	[305,225]	[48,50]	-7	hSpCas9	negative selection	289194
29195960	29195983	1	-	26472758	KBM7	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-1.8671290234882167	[1068,948]	[131,127]	-8	hSpCas9	negative selection	289195
29206778	29206801	1	+	26472758	KBM7	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-0.8895307681158124	[2268,2012]	[736,368]	-6	hSpCas9	negative selection	289196
29200555	29200578	1	+	26472758	KBM7	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-1.5356514931782779	[510,269]	[58,63]	-8	hSpCas9	negative selection	289197
29196192	29196215	1	+	26472758	KBM7	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	-1.006657404658142	[364,424]	[119,69]	-6	hSpCas9	negative selection	289198
29216624	29216647	1	-	26472758	KBM7	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-1.2931516778210443	[1983,2222]	[475,346]	-7	hSpCas9	negative selection	289199
29203195	29203218	1	-	26472758	KBM7	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.47348315345535497	[487,534]	[148,197]	-4	hSpCas9	negative selection	289200
29201978	29202001	1	-	26472758	KBM7	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-0.8726447067817359	[885,1147]	[173,347]	-6	hSpCas9	negative selection	289201
29200524	29200547	1	-	26472758	KBM7	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	-0.2844676631387886	[166,149]	[29,88]	-3	hSpCas9	negative selection	289202
29196232	29196255	1	-	26472758	KBM7	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-1.0525618814141022	[569,545]	[148,106]	-7	hSpCas9	negative selection	289203
29206805	29206828	1	+	26472758	Raji	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-0.6901236007276574	[145]	[20]	-5	hSpCas9	negative selection	480312
29195960	29195983	1	-	26472758	Raji	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	0.09467248362404557	[455]	[112]	0	hSpCas9	negative selection	480313
29206778	29206801	1	+	26472758	Raji	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-0.31518763659065185	[1023]	[190]	-3	hSpCas9	negative selection	480314
29200555	29200578	1	+	26472758	Raji	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	0.907711190537235	[146]	[63]	8	hSpCas9	negative selection	480315
29196192	29196215	1	+	26472758	Raji	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	0.5126400138598578	[147]	[48]	5	hSpCas9	negative selection	480316
29216624	29216647	1	-	26472758	Raji	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.24662453050768485	[863]	[168]	-2	hSpCas9	negative selection	480317
29203195	29203218	1	-	26472758	Raji	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.23839130146813078	[243]	[47]	-2	hSpCas9	negative selection	480318
29201978	29202001	1	-	26472758	Raji	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	0.5661934366813487	[421]	[144]	5	hSpCas9	negative selection	480319
29200524	29200547	1	-	26472758	Raji	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	-0.20520669493442656	[153]	[30]	-2	hSpCas9	negative selection	480320
29196232	29196255	1	-	26472758	Raji	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-0.010074046174577328	[242]	[55]	0	hSpCas9	negative selection	480321
29206805	29206828	1	+	26472758	K562	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-1.5850468959969055	[262]	[73]	-7	hSpCas9	negative selection	671430
29195960	29195983	1	-	26472758	K562	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	0.2744238655041006	[570]	[582]	2	hSpCas9	negative selection	671431
29206778	29206801	1	+	26472758	K562	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	0.25321269689828196	[1471]	[1480]	2	hSpCas9	negative selection	671432
29200555	29200578	1	+	26472758	K562	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-0.15106597419099638	[341]	[259]	-1	hSpCas9	negative selection	671433
29196192	29196215	1	+	26472758	K562	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	0.7766883345474134	[315]	[456]	6	hSpCas9	negative selection	671434
29216624	29216647	1	-	26472758	K562	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.47172674871808296	[1673]	[1018]	-3	hSpCas9	negative selection	671435
29203195	29203218	1	-	26472758	K562	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	0.6611097457978043	[435]	[581]	5	hSpCas9	negative selection	671436
29201978	29202001	1	-	26472758	K562	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	0.4122004185572399	[972]	[1092]	3	hSpCas9	negative selection	671437
29200524	29200547	1	-	26472758	K562	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	0.4704224025552738	[170]	[199]	4	hSpCas9	negative selection	671438
29196232	29196255	1	-	26472758	K562	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	0.6116708130632996	[375]	[484]	5	hSpCas9	negative selection	671439
29196193	29196216	1	+	26627737	DLD1	viability	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-0.12991817120422	[794]	[206,234,237]	-1	hSpCas9	negative selection	770691
29203195	29203218	1	-	26627737	DLD1	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.7583811167955565	[357]	[43,68,82]	-6	hSpCas9	negative selection	770692
29206873	29206896	1	-	26627737	DLD1	viability	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-0.7248325203711664	[1227]	[253,111,312]	-6	hSpCas9	negative selection	770693
29216065	29216088	1	-	26627737	DLD1	viability	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-1.471559665425741	[1257]	[167,124,132]	-8	hSpCas9	negative selection	770694
29216621	29216644	1	+	26627737	DLD1	viability	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.9107308567065759	[374]	[118,52,20]	-7	hSpCas9	negative selection	770695
29230762	29230785	1	+	26627737	DLD1	viability	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	-0.5989482782706518	[661]	[128,119,156]	-5	hSpCas9	negative selection	770696
29196193	29196216	1	+	26627737	GBM cells	viability after 5 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	0.3627672901075756	[384]	[189,340]	5	hSpCas9	negative selection	853006
29203195	29203218	1	-	26627737	GBM cells	viability after 5 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.3377863831346457	[151]	[62,65]	-5	hSpCas9	negative selection	853007
29206873	29206896	1	-	26627737	GBM cells	viability after 5 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	0.2655598900622489	[431]	[357,198]	4	hSpCas9	negative selection	853008
29216065	29216088	1	-	26627737	GBM cells	viability after 5 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	0.07021615093463995	[348]	[229,162]	1	hSpCas9	negative selection	853009
29216621	29216644	1	+	26627737	GBM cells	viability after 5 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.06089703499861554	[176]	[82,98]	-1	hSpCas9	negative selection	853010
29230762	29230785	1	+	26627737	GBM cells	viability after 5 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	0.1047500548402382	[312]	[177,182]	1	hSpCas9	negative selection	853011
29196193	29196216	1	+	26627737	GBM cells	viability after 13 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	0.5734086540918919	[384]	[333,291]	7	hSpCas9	negative selection	935321
29203195	29203218	1	-	26627737	GBM cells	viability after 13 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.684689348921103	[151]	[47,53]	-7	hSpCas9	negative selection	935322
29206873	29206896	1	-	26627737	GBM cells	viability after 13 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-0.12928643864149725	[431]	[269,168]	-1	hSpCas9	negative selection	935323
29216065	29216088	1	-	26627737	GBM cells	viability after 13 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-0.09785409220390667	[348]	[273,97]	-1	hSpCas9	negative selection	935324
29216621	29216644	1	+	26627737	GBM cells	viability after 13 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	0.06269652171080647	[176]	[155,54]	0	hSpCas9	negative selection	935325
29230762	29230785	1	+	26627737	GBM cells	viability after 13 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	-0.27598312799525526	[312]	[174,111]	-3	hSpCas9	negative selection	935326
29196193	29196216	1	+	26627737	GBM cells	viability after 21 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	0.2662519054229646	[384]	[261,241]	2	hSpCas9	negative selection	1017636
29203195	29203218	1	-	26627737	GBM cells	viability after 21 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	0.13657305287544397	[151]	[95,85]	1	hSpCas9	negative selection	1017637
29206873	29206896	1	-	26627737	GBM cells	viability after 21 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-0.9410291112321569	[431]	[139,105]	-7	hSpCas9	negative selection	1017638
29216065	29216088	1	-	26627737	GBM cells	viability after 21 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-0.3240992380821633	[348]	[175,128]	-3	hSpCas9	negative selection	1017639
29216621	29216644	1	+	26627737	GBM cells	viability after 21 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.7304971925659363	[176]	[58,56]	-6	hSpCas9	negative selection	1017640
29230762	29230785	1	+	26627737	GBM cells	viability after 21 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	-0.3260993968121045	[312]	[143,127]	-3	hSpCas9	negative selection	1017641
29196193	29196216	1	+	26627737	RPE1	viability after 9 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-0.8507219917130322	[2094]	[364,361]	-6	hSpCas9	negative selection	1099951
29203195	29203218	1	-	26627737	RPE1	viability after 9 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-1.3277435784772464	[490]	[55,67]	-7	hSpCas9	negative selection	1099952
29206873	29206896	1	-	26627737	RPE1	viability after 9 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-0.36960213001500497	[1668]	[334,493]	-3	hSpCas9	negative selection	1099953
29216065	29216088	1	-	26627737	RPE1	viability after 9 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-0.7044643705088685	[2033]	[216,614]	-5	hSpCas9	negative selection	1099954
29216621	29216644	1	+	26627737	RPE1	viability after 9 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.5445307065021238	[537]	[73,168]	-4	hSpCas9	negative selection	1099955
29230762	29230785	1	+	26627737	RPE1	viability after 9 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	0.46972175399161553	[862]	[295,474]	3	hSpCas9	negative selection	1099956
29196193	29196216	1	+	26627737	RPE1	viability after 12 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-0.8363686246090647	[2094]	[322,306]	-5	hSpCas9	negative selection	1182266
29203195	29203218	1	-	26627737	RPE1	viability after 12 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-1.5953219915507728	[490]	[48,37]	-8	hSpCas9	negative selection	1182267
29206873	29206896	1	-	26627737	RPE1	viability after 12 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-0.5527515060717094	[1668]	[124,496]	-4	hSpCas9	negative selection	1182268
29216065	29216088	1	-	26627737	RPE1	viability after 12 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-1.460893530418936	[2033]	[181,215]	-7	hSpCas9	negative selection	1182269
29216621	29216644	1	+	26627737	RPE1	viability after 12 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	0.15402896503936409	[537]	[171,148]	1	hSpCas9	negative selection	1182270
29230762	29230785	1	+	26627737	RPE1	viability after 12 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	0.8636030887285325	[862]	[485,353]	5	hSpCas9	negative selection	1182271
29196193	29196216	1	+	26627737	RPE1	viability after 15 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-2.4678114088631418	[2094]	[99,113]	-8	hSpCas9	negative selection	1264581
29203195	29203218	1	-	26627737	RPE1	viability after 15 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-1.241452294859073	[490]	[44,71]	-6	hSpCas9	negative selection	1264582
29206873	29206896	1	-	26627737	RPE1	viability after 15 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-0.9789739875152647	[1668]	[237,240]	-6	hSpCas9	negative selection	1264583
29216065	29216088	1	-	26627737	RPE1	viability after 15 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-1.7081447686483942	[2033]	[226,126]	-8	hSpCas9	negative selection	1264584
29216621	29216644	1	+	26627737	RPE1	viability after 15 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.3204216033497036	[537]	[184,60]	-2	hSpCas9	negative selection	1264585
29230762	29230785	1	+	26627737	RPE1	viability after 15 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	1.0227152736652259	[862]	[664,332]	6	hSpCas9	negative selection	1264586
29196193	29196216	1	+	26627737	RPE1	viability after 18 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-1.9900486027486446	[2094]	[107,178]	-8	hSpCas9	negative selection	1346896
29203195	29203218	1	-	26627737	RPE1	viability after 18 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-3.5053950964366782	[490]	[1,21]	-9	hSpCas9	negative selection	1346897
29206873	29206896	1	-	26627737	RPE1	viability after 18 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-1.4657008235752877	[1668]	[106,222]	-7	hSpCas9	negative selection	1346898
29216065	29216088	1	-	26627737	RPE1	viability after 18 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-2.410686086058434	[2033]	[109,95]	-8	hSpCas9	negative selection	1346899
29216621	29216644	1	+	26627737	RPE1	viability after 18 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.7380649105628517	[537]	[102,69]	-4	hSpCas9	negative selection	1346900
29230762	29230785	1	+	26627737	RPE1	viability after 18 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	1.1440301842172493	[862]	[636,383]	6	hSpCas9	negative selection	1346901
29196193	29196216	1	+	26627737	HeLa	viability after 8 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	0.4497275550860186	[616]	[435,322,356]	4	hSpCas9	negative selection	1429211
29203195	29203218	1	-	26627737	HeLa	viability after 8 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.020050004597828686	[210]	[114,85,76]	0	hSpCas9	negative selection	1429212
29206873	29206896	1	-	26627737	HeLa	viability after 8 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	0.04846666596609506	[643]	[531,208,188]	0	hSpCas9	negative selection	1429213
29216065	29216088	1	-	26627737	HeLa	viability after 8 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-1.0285126270292388	[1204]	[333,299,160]	-8	hSpCas9	negative selection	1429214
29216621	29216644	1	+	26627737	HeLa	viability after 8 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.6427501704856899	[469]	[271,20,130]	-6	hSpCas9	negative selection	1429215
29230762	29230785	1	+	26627737	HeLa	viability after 8 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	-0.37293084037818947	[552]	[191,168,196]	-4	hSpCas9	negative selection	1429216
29196193	29196216	1	+	26627737	HeLa	viability after 12 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	0.49779164122696307	[616]	[513,365,203]	4	hSpCas9	negative selection	1511526
29203195	29203218	1	-	26627737	HeLa	viability after 12 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.04898206275734074	[210]	[55,112,79]	0	hSpCas9	negative selection	1511527
29206873	29206896	1	-	26627737	HeLa	viability after 12 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	0.3150455673674769	[643]	[411,204,391]	2	hSpCas9	negative selection	1511528
29216065	29216088	1	-	26627737	HeLa	viability after 12 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-0.22551694844974302	[1204]	[419,506,341]	-2	hSpCas9	negative selection	1511529
29216621	29216644	1	+	26627737	HeLa	viability after 12 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-1.30732269707859	[469]	[164,30,46]	-8	hSpCas9	negative selection	1511530
29230762	29230785	1	+	26627737	HeLa	viability after 12 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	-0.12606802647803844	[552]	[231,198,198]	-1	hSpCas9	negative selection	1511531
29196193	29196216	1	+	26627737	HeLa	viability after 15 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	0.6091477790766088	[616]	[525,317,296]	5	hSpCas9	negative selection	1593841
29203195	29203218	1	-	26627737	HeLa	viability after 15 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.11058181572794179	[210]	[93,82,59]	-1	hSpCas9	negative selection	1593842
29206873	29206896	1	-	26627737	HeLa	viability after 15 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	0.8563978358015546	[643]	[388,429,616]	6	hSpCas9	negative selection	1593843
29216065	29216088	1	-	26627737	HeLa	viability after 15 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	0.23256586274390045	[1204]	[567,671,481]	2	hSpCas9	negative selection	1593844
29216621	29216644	1	+	26627737	HeLa	viability after 15 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.7317320313678528	[469]	[238,50,48]	-6	hSpCas9	negative selection	1593845
29230762	29230785	1	+	26627737	HeLa	viability after 15 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	0.8145805450452446	[552]	[205,422,574]	6	hSpCas9	negative selection	1593846
29196193	29196216	1	+	26627737	HeLa	viability after 18 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	0.6084144806846034	[616]	[351,263,296]	5	hSpCas9	negative selection	1676156
29203195	29203218	1	-	26627737	HeLa	viability after 18 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.14312532171262993	[210]	[56,71,59]	-1	hSpCas9	negative selection	1676157
29206873	29206896	1	-	26627737	HeLa	viability after 18 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	0.8491180773688235	[643]	[257,353,616]	6	hSpCas9	negative selection	1676158
29216065	29216088	1	-	26627737	HeLa	viability after 18 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	0.21852777821992597	[1204]	[372,552,481]	1	hSpCas9	negative selection	1676159
29216621	29216644	1	+	26627737	HeLa	viability after 18 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.7288043751357061	[469]	[160,41,48]	-6	hSpCas9	negative selection	1676160
29230762	29230785	1	+	26627737	HeLa	viability after 18 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	0.8171572710210526	[552]	[138,350,574]	6	hSpCas9	negative selection	1676161
29196193	29196216	1	+	26627737	HCT116	viability after 6 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-0.5391815140410908	[1200]	[156,114]	-3	hSpCas9	negative selection	1758471
29203195	29203218	1	-	26627737	HCT116	viability after 6 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	2.0873885908760452	[157]	[82,117]	8	hSpCas9	negative selection	1758472
29206873	29206896	1	-	26627737	HCT116	viability after 6 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	1.9623363678104053	[810]	[530,477]	8	hSpCas9	negative selection	1758473
29216065	29216088	1	-	26627737	HCT116	viability after 6 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	0.3262531125504551	[1239]	[498,103]	1	hSpCas9	negative selection	1758474
29216621	29216644	1	+	26627737	HCT116	viability after 6 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	0.27219308447995133	[393]	[68,77]	1	hSpCas9	negative selection	1758475
29230762	29230785	1	+	26627737	HCT116	viability after 6 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	1.256545382371351	[803]	[796,28]	6	hSpCas9	negative selection	1758476
29196193	29196216	1	+	26627737	HCT116	viability after 8 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-0.42189687009917487	[545]	[174,203,292]	-5	hSpCas9	negative selection	1840786
29203195	29203218	1	-	26627737	HCT116	viability after 8 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.28660651781999336	[155]	[20,74,113]	-3	hSpCas9	negative selection	1840787
29206873	29206896	1	-	26627737	HCT116	viability after 8 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-0.964880510634898	[815]	[207,278,203]	-8	hSpCas9	negative selection	1840788
29216065	29216088	1	-	26627737	HCT116	viability after 8 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-0.262526752451501	[464]	[176,237,224]	-3	hSpCas9	negative selection	1840789
29216621	29216644	1	+	26627737	HCT116	viability after 8 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.4946652113438551	[365]	[138,119,169]	-5	hSpCas9	negative selection	1840790
29230762	29230785	1	+	26627737	HCT116	viability after 8 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	0.3353921040424423	[418]	[249,316,305]	3	hSpCas9	negative selection	1840791
29196193	29196216	1	+	26627737	HCT116	viability after 9 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	0.5488014136941552	[1200]	[548,405]	4	hSpCas9	negative selection	1923101
29203195	29203218	1	-	26627737	HCT116	viability after 9 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	0.418048585525598	[157]	[90,28]	3	hSpCas9	negative selection	1923102
29206873	29206896	1	-	26627737	HCT116	viability after 9 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	2.1537276857668046	[810]	[995,937]	9	hSpCas9	negative selection	1923103
29216065	29216088	1	-	26627737	HCT116	viability after 9 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-0.09895668395862423	[1239]	[197,396]	0	hSpCas9	negative selection	1923104
29216621	29216644	1	+	26627737	HCT116	viability after 9 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	0.5973732425871396	[393]	[85,216]	4	hSpCas9	negative selection	1923105
29230762	29230785	1	+	26627737	HCT116	viability after 9 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	0.8523092274750005	[803]	[443,342]	6	hSpCas9	negative selection	1923106
29196193	29196216	1	+	26627737	HCT116	viability after 12 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-0.115048361230083	[545]	[235,331,230]	-1	hSpCas9	negative selection	2005416
29203195	29203218	1	-	26627737	HCT116	viability after 12 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.3052848035216057	[155]	[29,97,74]	-3	hSpCas9	negative selection	2005417
29206873	29206896	1	-	26627737	HCT116	viability after 12 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-1.2368880093006107	[815]	[171,234,140]	-8	hSpCas9	negative selection	2005418
29216065	29216088	1	-	26627737	HCT116	viability after 12 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-0.9472923937376476	[464]	[98,141,141]	-8	hSpCas9	negative selection	2005419
29216621	29216644	1	+	26627737	HCT116	viability after 12 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-1.0802975395685457	[365]	[56,95,122]	-8	hSpCas9	negative selection	2005420
29230762	29230785	1	+	26627737	HCT116	viability after 12 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	-0.49678824058696114	[418]	[207,131,122]	-5	hSpCas9	negative selection	2005421
29196193	29196216	1	+	26627737	HCT116	viability after 15 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-0.5554666818591826	[545]	[193,252,190]	-5	hSpCas9	negative selection	2087731
29203195	29203218	1	-	26627737	HCT116	viability after 15 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-1.3124251892585073	[155]	[0,70,31]	-8	hSpCas9	negative selection	2087732
29206873	29206896	1	-	26627737	HCT116	viability after 15 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-2.1208899447589262	[815]	[115,164,43]	-9	hSpCas9	negative selection	2087733
29216065	29216088	1	-	26627737	HCT116	viability after 15 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-2.0053908971413814	[464]	[43,102,49]	-9	hSpCas9	negative selection	2087734
29216621	29216644	1	+	26627737	HCT116	viability after 15 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-1.4394836918103837	[365]	[73,74,82]	-8	hSpCas9	negative selection	2087735
29230762	29230785	1	+	26627737	HCT116	viability after 15 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	-0.035056055998541336	[418]	[382,221,118]	0	hSpCas9	negative selection	2087736
29196193	29196216	1	+	26627737	HCT116	viability after 18 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-0.6187705321235777	[545]	[143,137,238]	-5	hSpCas9	negative selection	2170046
29203195	29203218	1	-	26627737	HCT116	viability after 18 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.5554966480387243	[155]	[10,75,65]	-5	hSpCas9	negative selection	2170047
29206873	29206896	1	-	26627737	HCT116	viability after 18 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-2.129976202996544	[815]	[79,88,101]	-9	hSpCas9	negative selection	2170048
29216065	29216088	1	-	26627737	HCT116	viability after 18 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-1.6922094435942194	[464]	[71,65,70]	-8	hSpCas9	negative selection	2170049
29216621	29216644	1	+	26627737	HCT116	viability after 18 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-1.2986457031537588	[365]	[45,114,50]	-8	hSpCas9	negative selection	2170050
29230762	29230785	1	+	26627737	HCT116	viability after 18 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	-0.38546078081384744	[418]	[244,119,99]	-4	hSpCas9	negative selection	2170051
29195070	29195093	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACACCACTGCACTCCAGCCAGG	MECR	ENSG00000116353	-0.6897978744123147	[436,52]	[50,12]	-4	dCas9-VP64	positive selection	2457821
29210083	29210106	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCTGCCTCCAAG	MECR	ENSG00000116353	3.3241346106645673	[178,128]	[9,695]	8	dCas9-VP64	positive selection	2462001
29195070	29195093	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACACCACTGCACTCCAGCCAGG	MECR	ENSG00000116353	0.2274396231328648	[285,212]	[141,51]	1	dCas9-VP64	positive selection	2553076
29210083	29210106	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCTGCCTCCAAG	MECR	ENSG00000116353	-0.24751078726835885	[128,142]	[21,50]	-2	dCas9-VP64	positive selection	2557256
29206895	29206918	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCTGACTCAGGAACCTGGCGG	MECR	ENSG00000116353	-1.3757228919275972	[3,3]	[0,0]	-9	hSpCas9	positive selection	3001788
29206873	29206896	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	0.07127669565132383	[3,3]	[1,4]	1	hSpCas9	positive selection	3001789
29216624	29216647	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.36960585947088853	[5,5]	[3,2]	-5	hSpCas9	positive selection	3001790
29206872	29206895	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTCCTCGCTGAACACAGCCTCGG	MECR	ENSG00000116353	-0.09773094591016931	[3,3]	[3,2]	-1	hSpCas9	positive selection	3001791
29206895	29206918	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCTGACTCAGGAACCTGGCGG	MECR	ENSG00000116353	-0.8680461452338591	[3,3]	[2,0]	-9	hSpCas9	positive selection	3069646
29206873	29206896	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-0.246281640811382	[3,3]	[2,1]	-4	hSpCas9	positive selection	3069647
29216624	29216647	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	0.20856291903756563	[5,5]	[4,3]	3	hSpCas9	positive selection	3069648
29206872	29206895	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTCCTCGCTGAACACAGCCTCGG	MECR	ENSG00000116353	-0.1886164391027303	[3,3]	[3,1]	-3	hSpCas9	positive selection	3069649
29216077	29216100		-	24336571	A375	resistance to PLX after 7 days	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.09437844351407176	[4,5]	[6,4]	3	hSpCas9	positive selection	3126958
29201942	29201965		-	24336571	A375	resistance to PLX after 7 days	CGAAATGAAAAACTTCTTTAAGG	MECR	ENSG00000116353	0.052540016467965245	[4,3]	[3,3]	2	hSpCas9	positive selection	3126959
29202005	29202028		-	24336571	A375	resistance to PLX after 7 days	GAGTGACAGACTGAAGAGTCTGG	MECR	ENSG00000116353	0.24151451678324798	[13,13]	[16,16]	7	hSpCas9	positive selection	3126960
29216049	29216072		-	24336571	A375	resistance to PLX after 7 days	GCGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	0.16482069192840748	[8,8]	[11,8]	5	hSpCas9	positive selection	3126961
29216621	29216644		+	24336571	A375	resistance to PLX after 7 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	0.06300934375304523	[6,4]	[5,6]	2	hSpCas9	positive selection	3126962
29201978	29202001		-	24336571	A375	resistance to PLX after 7 days	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	0.28932178877362946	[9,8]	[10,11]	7	hSpCas9	positive selection	3126963
29216672	29216695		-	24336571	A375	resistance to PLX after 7 days	TGTGCTTAGACTCAAGAACCTGG	MECR	ENSG00000116353	0.17678706471979022	[5,5]	[6,6]	5	hSpCas9	positive selection	3126964
29216077	29216100		-	24336571	A375	resistance to PLX after 14 days	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.47674084063120814	[1,4]	[1,1]	4	hSpCas9	positive selection	3184751
29201942	29201965		-	24336571	A375	resistance to PLX after 14 days	CGAAATGAAAAACTTCTTTAAGG	MECR	ENSG00000116353	0.6285028552438718	[3,3]	[2,2]	5	hSpCas9	positive selection	3184752
29202005	29202028		-	24336571	A375	resistance to PLX after 14 days	GAGTGACAGACTGAAGAGTCTGG	MECR	ENSG00000116353	-0.017869468950960227	[11,17]	[6,5]	0	hSpCas9	positive selection	3184753
29216049	29216072		-	24336571	A375	resistance to PLX after 14 days	GCGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	1.3557249206544406	[5,7]	[5,9]	8	hSpCas9	positive selection	3184754
29216621	29216644		+	24336571	A375	resistance to PLX after 14 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	0.921837355666489	[1,4]	[2,2]	7	hSpCas9	positive selection	3184755
29201978	29202001		-	24336571	A375	resistance to PLX after 14 days	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	1.50721404144015	[3,6]	[5,7]	9	hSpCas9	positive selection	3184756
29216672	29216695		-	24336571	A375	resistance to PLX after 14 days	TGTGCTTAGACTCAAGAACCTGG	MECR	ENSG00000116353	0.5882737487165841	[4,2]	[2,2]	5	hSpCas9	positive selection	3184757
29216077	29216100		-	24336571	A375	viability after 7 days	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.4698088156842686	[7]	[4,5]	-6	hSpCas9	negative selection	3242544
29201942	29201965		-	24336571	A375	viability after 7 days	CGAAATGAAAAACTTCTTTAAGG	MECR	ENSG00000116353	-0.9076843425130264	[8]	[4,3]	-8	hSpCas9	negative selection	3242545
29202005	29202028		-	24336571	A375	viability after 7 days	GAGTGACAGACTGAAGAGTCTGG	MECR	ENSG00000116353	0.03176795528513447	[14]	[13,13]	0	hSpCas9	negative selection	3242546
29216049	29216072		-	24336571	A375	viability after 7 days	GCGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	0.02899404377283149	[8]	[8,8]	0	hSpCas9	negative selection	3242547
29216621	29216644		+	24336571	A375	viability after 7 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.34366719716276384	[7]	[6,4]	-5	hSpCas9	negative selection	3242548
29201978	29202001		-	24336571	A375	viability after 7 days	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-0.8966478723436133	[18]	[9,8]	-8	hSpCas9	negative selection	3242549
29216672	29216695		-	24336571	A375	viability after 7 days	TGTGCTTAGACTCAAGAACCTGG	MECR	ENSG00000116353	-0.4336712554124965	[8]	[5,5]	-6	hSpCas9	negative selection	3242550
29216077	29216100		-	24336571	A375	viability after 14 days	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-1.0177724615562906	[7]	[1,4]	-8	hSpCas9	negative selection	3300337
29201942	29201965		-	24336571	A375	viability after 14 days	CGAAATGAAAAACTTCTTTAAGG	MECR	ENSG00000116353	-0.8778577205685235	[8]	[3,3]	-8	hSpCas9	negative selection	3300338
29202005	29202028		-	24336571	A375	viability after 14 days	GAGTGACAGACTGAAGAGTCTGG	MECR	ENSG00000116353	0.11620607545082597	[14]	[11,17]	1	hSpCas9	negative selection	3300339
29216049	29216072		-	24336571	A375	viability after 14 days	GCGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	-0.33511669374529224	[8]	[5,7]	-4	hSpCas9	negative selection	3300340
29216621	29216644		+	24336571	A375	viability after 14 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.9157250049546362	[7]	[1,4]	-8	hSpCas9	negative selection	3300341
29201978	29202001		-	24336571	A375	viability after 14 days	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-1.7009740057057756	[18]	[3,6]	-9	hSpCas9	negative selection	3300342
29216672	29216695		-	24336571	A375	viability after 14 days	TGTGCTTAGACTCAAGAACCTGG	MECR	ENSG00000116353	-0.9658008179064806	[8]	[4,2]	-8	hSpCas9	negative selection	3300343
29216088	29216111	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	3.556886493304743	[12,12]	[0,0]	9	hSpCas9	positive selection	3378894
29206895	29206918	1	-	26780180	HT29	viability (Avana library 4 designs)	CTTCTGACTCAGGAACCTGGCGG	MECR	ENSG00000116353	1.11116136561944	[]	[]	4	hSpCas9	negative selection	3439514
29206873	29206896	1	-	26780180	HT29	viability (Avana library 4 designs)	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	1.23998405559812	[]	[]	5	hSpCas9	negative selection	3439515
29216624	29216647	1	-	26780180	HT29	viability (Avana library 4 designs)	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.0703479949903489	[]	[]	-1	hSpCas9	negative selection	3439516
29206871	29206894	1	+	26780180	HT29	viability (Avana library 4 designs)	TTCCTCGCTGAACACAGCCTCGG	MECR	ENSG00000116353	0.621929679798577	[]	[]	2	hSpCas9	negative selection	3439517
29206895	29206918	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCTGACTCAGGAACCTGGCGG	MECR	ENSG00000116353	-10.5760460928203	[]	[]	-8	hSpCas9	negative selection	3529297
29216624	29216647	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-5.00256700015701	[]	[]	-5	hSpCas9	negative selection	3529298
29206873	29206896	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	1.15829698344278	[]	[]	1	hSpCas9	negative selection	3529299
29206871	29206894	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTCCTCGCTGAACACAGCCTCGG	MECR	ENSG00000116353	4.57653650319934	[]	[]	7	hSpCas9	negative selection	3529300
29216127	29216150	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTCTCCCTCAGGAAACTACGG	MECR	ENSG00000116353	-6.49177466814619	[]	[]	-6	hSpCas9	negative selection	3529301
29216096	29216119	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGAACTGCCTGCTGTTGGAGGG	MECR	ENSG00000116353	2.20707990004778	[]	[]	3	hSpCas9	negative selection	3529302
29206895	29206918	1	-	26780180	A375	viability (Avana lentiGuide)	CTTCTGACTCAGGAACCTGGCGG	MECR	ENSG00000116353	11.7671053992385	[]	[]	7	hSpCas9	negative selection	3637956
29216624	29216647	1	-	26780180	A375	viability (Avana lentiGuide)	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	13.340783008977	[]	[]	7	hSpCas9	negative selection	3637957
29206873	29206896	1	-	26780180	A375	viability (Avana lentiGuide)	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	13.6580403552687	[]	[]	7	hSpCas9	negative selection	3637958
29206871	29206894	1	+	26780180	A375	viability (Avana lentiGuide)	TTCCTCGCTGAACACAGCCTCGG	MECR	ENSG00000116353	-5.51955052961685	[]	[]	-8	hSpCas9	negative selection	3637959
29216127	29216150	1	-	26780180	A375	viability (Avana lentiGuide)	TCTTCTCCCTCAGGAAACTACGG	MECR	ENSG00000116353	18.1220355020051	[]	[]	8	hSpCas9	negative selection	3637960
29216096	29216119	1	-	26780180	A375	viability (Avana lentiGuide)	CTGAACTGCCTGCTGTTGGAGGG	MECR	ENSG00000116353	13.966202775592	[]	[]	7	hSpCas9	negative selection	3637961
29206895	29206918	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCTGACTCAGGAACCTGGCGG	MECR	ENSG00000116353	-0.5024683690928332	[4]	[2,3]	-6	hSpCas9	positive selection	3746615
29216624	29216647	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.10841397950248247	[6]	[6,4]	-2	hSpCas9	positive selection	3746616
29206873	29206896	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	0.16245039102832118	[5]	[6,5]	4	hSpCas9	positive selection	3746617
29206871	29206894	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCCTCGCTGAACACAGCCTCGG	MECR	ENSG00000116353	0.14399587546553905	[5]	[5,5]	4	hSpCas9	positive selection	3746618
29216127	29216150	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTCTCCCTCAGGAAACTACGG	MECR	ENSG00000116353	-0.4525008430268848	[4]	[4,2]	-6	hSpCas9	positive selection	3746619
29216096	29216119	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGAACTGCCTGCTGTTGGAGGG	MECR	ENSG00000116353	0.16536870044804275	[5]	[5,5]	4	hSpCas9	positive selection	3746620
29206895	29206918	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCTGACTCAGGAACCTGGCGG	MECR	ENSG00000116353	-0.1954786874150544	[5]	[1,5]	-3	hSpCas9	positive selection	3855222
29216624	29216647	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.16852227390155758	[7]	[6,4]	-2	hSpCas9	positive selection	3855223
29206873	29206896	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	0.11041818917263575	[5]	[5,4]	2	hSpCas9	positive selection	3855224
29206871	29206894	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCCTCGCTGAACACAGCCTCGG	MECR	ENSG00000116353	0.3763272238430226	[5]	[6,6]	9	hSpCas9	positive selection	3855225
29216127	29216150	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTCTCCCTCAGGAAACTACGG	MECR	ENSG00000116353	0.28274033781303703	[4]	[5,4]	7	hSpCas9	positive selection	3855226
29216096	29216119	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGAACTGCCTGCTGTTGGAGGG	MECR	ENSG00000116353	0.020806156964737643	[6]	[4,5]	0	hSpCas9	positive selection	3855227
29216077	29216100	1	-	26780180	A375	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.999463538930877	[]	[]	4	hSpCas9	negative selection	3960701
29216088	29216111	1	+	26780180	A375	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.278329909977692	[]	[]	0	hSpCas9	negative selection	3960702
29206888	29206911	1	-	26780180	A375	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	1.10131351728268	[]	[]	5	hSpCas9	negative selection	3960703
29206833	29206856	1	+	26780180	A375	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	1.31853580840187	[]	[]	7	hSpCas9	negative selection	3960704
29216587	29216610	1	-	26780180	A375	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	1.91535082158875	[]	[]	9	hSpCas9	negative selection	3960705
29216590	29216613	1	+	26780180	A375	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.87724884865755	[]	[]	3	hSpCas9	negative selection	3960706
29216077	29216100	1	-	26780180	HT29	viability (GeCKOv2 library)	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	1.33086451999295	[]	[]	6	hSpCas9	negative selection	4068667
29216088	29216111	1	+	26780180	HT29	viability (GeCKOv2 library)	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.679754819054455	[]	[]	2	hSpCas9	negative selection	4068668
29206888	29206911	1	-	26780180	HT29	viability (GeCKOv2 library)	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	1.53299354083561	[]	[]	7	hSpCas9	negative selection	4068669
29206833	29206856	1	+	26780180	HT29	viability (GeCKOv2 library)	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.225480385330503	[]	[]	0	hSpCas9	negative selection	4068670
29216587	29216610	1	-	26780180	HT29	viability (GeCKOv2 library)	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	1.73475584772949	[]	[]	8	hSpCas9	negative selection	4068671
29216590	29216613	1	+	26780180	HT29	viability (GeCKOv2 library)	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.46983200117066	[]	[]	1	hSpCas9	negative selection	4068672
29216077	29216100	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.5065032369333489	[2]	[1,0]	-8	hSpCas9	positive selection	4151258
29201942	29201965	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAAATGAAAAACTTCTTTAAGG	MECR	ENSG00000116353	-0.49226325497718737	[2]	[0,1]	-8	hSpCas9	positive selection	4151259
29202005	29202028	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGTGACAGACTGAAGAGTCTGG	MECR	ENSG00000116353	-0.11588084367540341	[4]	[1,2]	-3	hSpCas9	positive selection	4151260
29216049	29216072	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	0.04046865577057307	[3]	[1,2]	1	hSpCas9	positive selection	4151261
29216621	29216644	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	0.025659201846218227	[2]	[1,1]	0	hSpCas9	positive selection	4151262
29201978	29202001	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-0.04587908590371035	[3]	[2,2]	-1	hSpCas9	positive selection	4151263
29216672	29216695	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTGCTTAGACTCAAGAACCTGG	MECR	ENSG00000116353	-0.042787545458597476	[2]	[1,1]	-1	hSpCas9	positive selection	4151264
29216077	29216100	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.03662606518788725	[2]	[0,0,1,0]	0	hSpCas9	positive selection	4215280
29201942	29201965	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAAATGAAAAACTTCTTTAAGG	MECR	ENSG00000116353	-0.36457363388154473	[3]	[0,3,0,0]	-5	hSpCas9	positive selection	4215281
29202005	29202028	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGTGACAGACTGAAGAGTCTGG	MECR	ENSG00000116353	1.2129061064075752	[0]	[3,0,0,0]	8	hSpCas9	positive selection	4215282
29216049	29216072	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	0.01737427087770306	[3]	[2,2,1,0]	0	hSpCas9	positive selection	4215283
29216621	29216644	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	0.7073210268088028	[3]	[2,1,0,3]	4	hSpCas9	positive selection	4215284
29201978	29202001	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	0.3661328218006674	[4]	[3,2,2,1]	2	hSpCas9	positive selection	4215285
29216672	29216695	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTGCTTAGACTCAAGAACCTGG	MECR	ENSG00000116353	-0.3532216176105259	[3]	[0,1,1,0]	-5	hSpCas9	positive selection	4215286
29206888	29206911	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.7567178529708529	[1]	[0,0]	-9	hSpCas9	positive selection	4282389
29206833	29206856	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.27195930593390766	[4]	[4,3]	5	hSpCas9	positive selection	4282390
29216077	29216100	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.5889715807010583	[1]	[0,0]	-8	hSpCas9	positive selection	4282391
29216088	29216111	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.3920313893931191	[0]	[0,0]	-7	hSpCas9	positive selection	4346647
29216590	29216613	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.6740196769906155	[1]	[2,2]	9	hSpCas9	positive selection	4346648
29216587	29216610	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.13833727053034978	[3]	[2,2]	-3	hSpCas9	positive selection	4346649
29206802	29206824	1	+	27760321	OCIAML3	viability	TGTGCAGGGATTGACACCCAGG	MECR	ENSG00000116353	-0.3972390436739851	[358,318]	[200,200]	-4	hSpCas9	negative selection	4417512
29206841	29206863	1	+	27760321	OCIAML3	viability	AGGGATGTCACTCGGAACTTGG	MECR	ENSG00000116353	0.2251677043935569	[354,284]	[266,321]	2	hSpCas9	negative selection	4417513
29206888	29206910	1	-	27760321	OCIAML3	viability	TCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.35218531979338596	[734,544]	[372,408]	-4	hSpCas9	negative selection	4417514
29216049	29216071	1	-	27760321	OCIAML3	viability	CGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	-0.10255477261300938	[752,601]	[464,523]	-1	hSpCas9	negative selection	4417515
29216077	29216099	1	-	27760321	OCIAML3	viability	GGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.23445537114988468	[285,248]	[156,203]	-2	hSpCas9	negative selection	4417516
29206802	29206824	1	+	27760321	OCIAML2	viability	TGTGCAGGGATTGACACCCAGG	MECR	ENSG00000116353	-0.3136370491559254	[358,318]	[174,279]	-4	hSpCas9	negative selection	4500975
29206841	29206863	1	+	27760321	OCIAML2	viability	AGGGATGTCACTCGGAACTTGG	MECR	ENSG00000116353	0.06347164444970421	[354,284]	[189,372]	0	hSpCas9	negative selection	4500976
29206888	29206910	1	-	27760321	OCIAML2	viability	TCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.008237971041382575	[734,544]	[443,610]	0	hSpCas9	negative selection	4500977
29216049	29216071	1	-	27760321	OCIAML2	viability	CGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	0.23275109237180203	[752,601]	[603,687]	3	hSpCas9	negative selection	4500978
29216077	29216099	1	-	27760321	OCIAML2	viability	GGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.8347551130011945	[285,248]	[296,500]	9	hSpCas9	negative selection	4500979
29206802	29206824	1	+	27760321	MV411	viability	TGTGCAGGGATTGACACCCAGG	MECR	ENSG00000116353	-0.3291867748485421	[358,318]	[164,196]	-2	hSpCas9	negative selection	4584438
29206841	29206863	1	+	27760321	MV411	viability	AGGGATGTCACTCGGAACTTGG	MECR	ENSG00000116353	0.2689542059602612	[354,284]	[246,261]	2	hSpCas9	negative selection	4584439
29206888	29206910	1	-	27760321	MV411	viability	TCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.3958409149854124	[734,544]	[461,683]	3	hSpCas9	negative selection	4584440
29216049	29216071	1	-	27760321	MV411	viability	CGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	0.28038294903088556	[752,601]	[305,890]	2	hSpCas9	negative selection	4584441
29216077	29216099	1	-	27760321	MV411	viability	GGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.9984645884012271	[285,248]	[384,301]	7	hSpCas9	negative selection	4584442
29206802	29206824	1	+	27760321	HL60	viability	TGTGCAGGGATTGACACCCAGG	MECR	ENSG00000116353	-1.4279849383062486	[358,318]	[160,40]	-8	hSpCas9	negative selection	4667901
29206841	29206863	1	+	27760321	HL60	viability	AGGGATGTCACTCGGAACTTGG	MECR	ENSG00000116353	-0.30003834386350736	[354,284]	[164,259]	-3	hSpCas9	negative selection	4667902
29206888	29206910	1	-	27760321	HL60	viability	TCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.5418438129757366	[734,544]	[352,358]	-5	hSpCas9	negative selection	4667903
29216049	29216071	1	-	27760321	HL60	viability	CGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	-0.6024884447615203	[752,601]	[390,331]	-6	hSpCas9	negative selection	4667904
29216077	29216099	1	-	27760321	HL60	viability	GGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-1.1638677052223312	[285,248]	[106,86]	-8	hSpCas9	negative selection	4667905
29206802	29206824	1	+	27760321	HT1080	viability	TGTGCAGGGATTGACACCCAGG	MECR	ENSG00000116353	-4.1835245965723855	[318,248]	[10,0]	-8	hSpCas9	negative selection	4751364
29206841	29206863	1	+	27760321	HT1080	viability	AGGGATGTCACTCGGAACTTGG	MECR	ENSG00000116353	-6.661095341278961	[284,222]	[0,0]	-9	hSpCas9	negative selection	4751365
29206888	29206910	1	-	27760321	HT1080	viability	TCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-1.652048476172189	[544,424]	[81,38]	-5	hSpCas9	negative selection	4751366
29216049	29216071	1	-	27760321	HT1080	viability	CGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	-2.055075772893881	[601,469]	[69,30]	-6	hSpCas9	negative selection	4751367
29216077	29216099	1	-	27760321	HT1080	viability	GGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-2.2772857300744436	[248,194]	[33,0]	-6	hSpCas9	negative selection	4751368
29206802	29206824	1	+	27760321	HT29	viability after 7 days	TGTGCAGGGATTGACACCCAGG	MECR	ENSG00000116353	-0.25580410585199576	[318,248]	[287,432,196]	-4	hSpCas9	negative selection	4834827
29206841	29206863	1	+	27760321	HT29	viability after 7 days	AGGGATGTCACTCGGAACTTGG	MECR	ENSG00000116353	-0.08501994239687238	[284,222]	[268,410,239]	-1	hSpCas9	negative selection	4834828
29206888	29206910	1	-	27760321	HT29	viability after 7 days	TCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.46829582641431844	[544,424]	[889,818,880]	7	hSpCas9	negative selection	4834829
29216049	29216071	1	-	27760321	HT29	viability after 7 days	CGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	0.03724101309681316	[601,469]	[755,712,659]	0	hSpCas9	negative selection	4834830
29216077	29216099	1	-	27760321	HT29	viability after 7 days	GGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.13214429048437482	[248,194]	[257,364,160]	-2	hSpCas9	negative selection	4834831
29206802	29206824	1	+	27760321	HT29	viability after 25 days	TGTGCAGGGATTGACACCCAGG	MECR	ENSG00000116353	0.035362392823723554	[318,248]	[309,336,353]	0	hSpCas9	negative selection	4918290
29206841	29206863	1	+	27760321	HT29	viability after 25 days	AGGGATGTCACTCGGAACTTGG	MECR	ENSG00000116353	0.6804883095301925	[284,222]	[494,383,519]	7	hSpCas9	negative selection	4918291
29206888	29206910	1	-	27760321	HT29	viability after 25 days	TCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.4560488099302691	[544,424]	[617,881,791]	5	hSpCas9	negative selection	4918292
29216049	29216071	1	-	27760321	HT29	viability after 25 days	CGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	0.852626312270678	[601,469]	[835,1260,1251]	8	hSpCas9	negative selection	4918293
29216077	29216099	1	-	27760321	HT29	viability after 25 days	GGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.7092286545051385	[248,194]	[428,339,480]	7	hSpCas9	negative selection	4918294
29206802	29206824	1	+	27760321	HT29	viability after 22 days	TGTGCAGGGATTGACACCCAGG	MECR	ENSG00000116353	0.0063772691433313655	[318,248]	[201,540,248]	0	hSpCas9	negative selection	5001753
29206841	29206863	1	+	27760321	HT29	viability after 22 days	AGGGATGTCACTCGGAACTTGG	MECR	ENSG00000116353	0.5718709547191166	[284,222]	[313,554,443]	6	hSpCas9	negative selection	5001754
29206888	29206910	1	-	27760321	HT29	viability after 22 days	TCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.38456471472581977	[544,424]	[558,845,795]	4	hSpCas9	negative selection	5001755
29216049	29216071	1	-	27760321	HT29	viability after 22 days	CGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	0.7322634017998751	[601,469]	[903,1214,971]	8	hSpCas9	negative selection	5001756
29216077	29216099	1	-	27760321	HT29	viability after 22 days	GGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.8889891312880467	[248,194]	[505,471,446]	8	hSpCas9	negative selection	5001757
29206802	29206824	1	+	27760321	HT29	viability after 19 days	TGTGCAGGGATTGACACCCAGG	MECR	ENSG00000116353	-0.24066539963572608	[318,248]	[233,304,280]	-2	hSpCas9	negative selection	5085216
29206841	29206863	1	+	27760321	HT29	viability after 19 days	AGGGATGTCACTCGGAACTTGG	MECR	ENSG00000116353	0.06708294192057845	[284,222]	[411,390,127]	0	hSpCas9	negative selection	5085217
29206888	29206910	1	-	27760321	HT29	viability after 19 days	TCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.3835052853501756	[544,424]	[579,847,726]	3	hSpCas9	negative selection	5085218
29216049	29216071	1	-	27760321	HT29	viability after 19 days	CGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	1.0223285075803452	[601,469]	[962,1439,1299]	9	hSpCas9	negative selection	5085219
29216077	29216099	1	-	27760321	HT29	viability after 19 days	GGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.8867082724281816	[248,194]	[449,318,630]	8	hSpCas9	negative selection	5085220
29206802	29206824	1	+	27760321	HT29	viability after 16 days	TGTGCAGGGATTGACACCCAGG	MECR	ENSG00000116353	0.11517500358620014	[318,248]	[410,332,294]	1	hSpCas9	negative selection	5168679
29206841	29206863	1	+	27760321	HT29	viability after 16 days	AGGGATGTCACTCGGAACTTGG	MECR	ENSG00000116353	-0.03764988625063703	[284,222]	[410,250,181]	0	hSpCas9	negative selection	5168680
29206888	29206910	1	-	27760321	HT29	viability after 16 days	TCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.5470999419987871	[544,424]	[742,776,853]	6	hSpCas9	negative selection	5168681
29216049	29216071	1	-	27760321	HT29	viability after 16 days	CGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	0.5949767462144103	[601,469]	[1454,719,598]	7	hSpCas9	negative selection	5168682
29216077	29216099	1	-	27760321	HT29	viability after 16 days	GGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.595780799452457	[248,194]	[340,337,444]	7	hSpCas9	negative selection	5168683
29206802	29206824	1	+	27760321	HT29	viability after 13 days	TGTGCAGGGATTGACACCCAGG	MECR	ENSG00000116353	-0.0035895011576842495	[318,248]	[246,459,281]	0	hSpCas9	negative selection	5252142
29206841	29206863	1	+	27760321	HT29	viability after 13 days	AGGGATGTCACTCGGAACTTGG	MECR	ENSG00000116353	0.2827668762956952	[284,222]	[400,359,316]	3	hSpCas9	negative selection	5252143
29206888	29206910	1	-	27760321	HT29	viability after 13 days	TCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.47933020103892254	[544,424]	[924,837,600]	6	hSpCas9	negative selection	5252144
29216049	29216071	1	-	27760321	HT29	viability after 13 days	CGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	0.040207050972069	[601,469]	[598,829,497]	0	hSpCas9	negative selection	5252145
29216077	29216099	1	-	27760321	HT29	viability after 13 days	GGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.3246144248979941	[248,194]	[162,262,191]	-4	hSpCas9	negative selection	5252146
29206802	29206824	1	+	27760321	HT29	viability after 10 days	TGTGCAGGGATTGACACCCAGG	MECR	ENSG00000116353	-0.6098910242214574	[318,248]	[226,334,139]	-6	hSpCas9	negative selection	5335605
29206841	29206863	1	+	27760321	HT29	viability after 10 days	AGGGATGTCACTCGGAACTTGG	MECR	ENSG00000116353	-0.21822371456481504	[284,222]	[129,377,311]	-3	hSpCas9	negative selection	5335606
29206888	29206910	1	-	27760321	HT29	viability after 10 days	TCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.468646658440131	[544,424]	[773,893,846]	6	hSpCas9	negative selection	5335607
29216049	29216071	1	-	27760321	HT29	viability after 10 days	CGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	0.0748570451960896	[601,469]	[749,613,746]	1	hSpCas9	negative selection	5335608
29216077	29216099	1	-	27760321	HT29	viability after 10 days	GGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.09187813640351117	[248,194]	[338,328,220]	1	hSpCas9	negative selection	5335609
29206802	29206824	1	+	27760321	MOLM13	viability	TGTGCAGGGATTGACACCCAGG	MECR	ENSG00000116353	0.40425718576419245	[358,318]	[511,31]	3	hSpCas9	negative selection	5419068
29206841	29206863	1	+	27760321	MOLM13	viability	AGGGATGTCACTCGGAACTTGG	MECR	ENSG00000116353	0.884517565856796	[354,284]	[298,358]	6	hSpCas9	negative selection	5419069
29206888	29206910	1	-	27760321	MOLM13	viability	TCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.08670630323920558	[734,544]	[318,431]	0	hSpCas9	negative selection	5419070
29216049	29216071	1	-	27760321	MOLM13	viability	CGGTGGGCAGCAATGTGACCGG	MECR	ENSG00000116353	-0.3703328284715606	[752,601]	[327,264]	-2	hSpCas9	negative selection	5419071
29216077	29216099	1	-	27760321	MOLM13	viability	GGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.44305335099156484	[285,248]	[214,21]	-3	hSpCas9	negative selection	5419072
29230822	29230845	1	+	27661255	K562	viability	GTCCGTGACAGCCAGAAGCTGGG	MECR	ENSG00000116353	-0.1257754297964363	[460,451]	[356,314]	-4	dCas9-KRAB	negative selection	5492765
29230868	29230891	1	+	27661255	K562	viability	GGGGGTTCGCACCCGCCACAGGG	MECR	ENSG00000116353	-0.0172882715141938	[763,810]	[689,561]	0	dCas9-KRAB	negative selection	5492766
29230530	29230553	1	-	27661255	K562	viability	GACCCGAGAGGCAATTATCAGGG	MECR	ENSG00000116353	0.042797439903158874	[1353,1605]	[1327,1116]	1	dCas9-KRAB	negative selection	5492767
29230853	29230876	1	-	27661255	K562	viability	GAACCCCCGCCCGGCAGTGGCGG	MECR	ENSG00000116353	-0.18087400875312865	[582,634]	[448,410]	-5	dCas9-KRAB	negative selection	5492768
29230862	29230885	1	-	27661255	K562	viability	GGCGGGTGCGAACCCCCGCCCGG	MECR	ENSG00000116353	0.08336834204586463	[227,263]	[252,168]	3	dCas9-KRAB	negative selection	5492769
29230880	29230903	1	-	27661255	K562	viability	GGGTCTGCAGTACCCTGTGGCGG	MECR	ENSG00000116353	-0.032539213482418755	[790,1037]	[808,626]	-1	dCas9-KRAB	negative selection	5492770
29230900	29230923	1	-	27661255	K562	viability	GTTGGTTGGAGCGAGCATGTGGG	MECR	ENSG00000116353	0.005819907596361973	[880,1171]	[932,721]	0	dCas9-KRAB	negative selection	5492771
29230914	29230937	1	-	27661255	K562	viability	GCGTCAGGCTCTGTGTTGGTTGG	MECR	ENSG00000116353	0.12783238613389236	[242,200]	[208,181]	4	dCas9-KRAB	negative selection	5492772
29206888	29206911	1	-	27260156	BXPC3	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.03797200098383868	[155]	[89,184,154,256]	0	hSpCas9	negative selection	5554849
29206833	29206856	1	+	27260156	BXPC3	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.1510234131991497	[1023]	[1166,1271,1327,949]	3	hSpCas9	negative selection	5554850
29216077	29216100	1	-	27260156	BXPC3	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.05318474978765053	[113]	[104,113,142,95]	-1	hSpCas9	negative selection	5554851
29216088	29216111	1	+	27260156	BXPC3	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.47517354290329017	[40]	[26,22,28,46]	-8	hSpCas9	negative selection	5619107
29216590	29216613	1	+	27260156	BXPC3	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.6825942955251604	[179]	[376,232,254,340]	9	hSpCas9	negative selection	5619108
29216587	29216610	1	-	27260156	BXPC3	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.4044803255093618	[663]	[439,540,597,524]	-7	hSpCas9	negative selection	5619109
29206888	29206911	1	-	27260156	A673	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.43542235997676215	[155]	[171,169,96,116]	-8	hSpCas9	negative selection	5676100
29206833	29206856	1	+	27260156	A673	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.4236947474377416	[1023]	[1058,974,822,817]	-8	hSpCas9	negative selection	5676101
29216077	29216100	1	-	27260156	A673	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.3522782244550333	[113]	[108,98,99,121]	-7	hSpCas9	negative selection	5676102
29216088	29216111	1	+	27260156	A673	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.2459695473108412	[40]	[49,32,44,38]	-6	hSpCas9	negative selection	5740358
29216590	29216613	1	+	27260156	A673	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.4104489877691515	[179]	[305,283,241,320]	8	hSpCas9	negative selection	5740359
29216587	29216610	1	-	27260156	A673	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-1.0618001497254168	[663]	[422,345,346,418]	-9	hSpCas9	negative selection	5740360
29206888	29206911	1	-	27260156	A375	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.005687360189803536	[155]	[135,160,205,214]	0	hSpCas9	negative selection	5797351
29206833	29206856	1	+	27260156	A375	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.39207887516706486	[1023]	[941,1003,1054,681]	-5	hSpCas9	negative selection	5797352
29216077	29216100	1	-	27260156	A375	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.07306694752172627	[113]	[126,261,152,45]	1	hSpCas9	negative selection	5797353
29216088	29216111	1	+	27260156	A375	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.5930773092684407	[40]	[109,76,70,35]	8	hSpCas9	negative selection	5861609
29216590	29216613	1	+	27260156	A375	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	1.1742016024404602	[179]	[575,451,376,486]	9	hSpCas9	negative selection	5861610
29216587	29216610	1	-	27260156	A375	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-1.4758450673113352	[663]	[317,418,145,253]	-9	hSpCas9	negative selection	5861611
29206888	29206911	1	-	27260156	COLO741	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.27048560816825074	[155]	[140,195,156]	-5	hSpCas9	negative selection	5918602
29206833	29206856	1	+	27260156	COLO741	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.15852663140609602	[1023]	[1590,1496,1311]	3	hSpCas9	negative selection	5918603
29216077	29216100	1	-	27260156	COLO741	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.2869646831464807	[113]	[193,188,152]	6	hSpCas9	negative selection	5918604
29216088	29216111	1	+	27260156	COLO741	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.11262806547007731	[40]	[103,44,26]	2	hSpCas9	negative selection	5982860
29216590	29216613	1	+	27260156	COLO741	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.7541172582999897	[179]	[511,285,375]	9	hSpCas9	negative selection	5982861
29216587	29216610	1	-	27260156	COLO741	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.38265010248755393	[663]	[816,600,553]	-7	hSpCas9	negative selection	5982862
29206888	29206911	1	-	27260156	CAL120	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.012861579043238702	[155]	[304,92,195]	0	hSpCas9	negative selection	6039853
29206833	29206856	1	+	27260156	CAL120	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.05796492995607072	[1023]	[1273,1280,1125]	-1	hSpCas9	negative selection	6039854
29216077	29216100	1	-	27260156	CAL120	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.7275802837442589	[113]	[41,43,162]	-7	hSpCas9	negative selection	6039855
29216088	29216111	1	+	27260156	CAL120	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.2352332423239316	[40]	[23,53,48]	-3	hSpCas9	negative selection	6104111
29216590	29216613	1	+	27260156	CAL120	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.7554884041410613	[179]	[350,390,387]	9	hSpCas9	negative selection	6104112
29216587	29216610	1	-	27260156	CAL120	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.5585215241235058	[663]	[780,598,339]	-7	hSpCas9	negative selection	6104113
29206888	29206911	1	-	27260156	CADOES1	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.06938830637740145	[155]	[106,180,171,148]	1	hSpCas9	negative selection	6161104
29206833	29206856	1	+	27260156	CADOES1	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.0995998744064106	[1023]	[855,803,885,1013]	-2	hSpCas9	negative selection	6161105
29216077	29216100	1	-	27260156	CADOES1	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.4256401739427902	[113]	[93,253,79,141]	7	hSpCas9	negative selection	6161106
29216088	29216111	1	+	27260156	CADOES1	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.4607406953554354	[40]	[20,7,48,32]	-7	hSpCas9	negative selection	6225362
29216590	29216613	1	+	27260156	CADOES1	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.6323414087381211	[179]	[210,276,268,281]	8	hSpCas9	negative selection	6225363
29216587	29216610	1	-	27260156	CADOES1	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.41596322176845224	[663]	[439,290,609,511]	-6	hSpCas9	negative selection	6225364
29206888	29206911	1	-	27260156	EWS502	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.2847605189708051	[155]	[236,206,139,215]	5	hSpCas9	negative selection	6282355
29206833	29206856	1	+	27260156	EWS502	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.18580613022480108	[1023]	[1174,925,1201,1677]	3	hSpCas9	negative selection	6282356
29216077	29216100	1	-	27260156	EWS502	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.07116378960755476	[113]	[133,111,161,96]	1	hSpCas9	negative selection	6282357
29216088	29216111	1	+	27260156	EWS502	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.00865583725965946	[40]	[44,39,50,35]	0	hSpCas9	negative selection	6346613
29216590	29216613	1	+	27260156	EWS502	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.36731595684917173	[179]	[298,124,266,293]	6	hSpCas9	negative selection	6346614
29216587	29216610	1	-	27260156	EWS502	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.4992153724278046	[663]	[590,474,521,381]	-7	hSpCas9	negative selection	6346615
29206888	29206911	1	-	27260156	EW8	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.08644199970550481	[155]	[263,126,68,101]	1	hSpCas9	negative selection	6403606
29206833	29206856	1	+	27260156	EW8	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.06378729334000255	[1023]	[874,943,779,883]	1	hSpCas9	negative selection	6403607
29216077	29216100	1	-	27260156	EW8	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.33998564714525914	[113]	[72,83,53,83]	-6	hSpCas9	negative selection	6403608
29216088	29216111	1	+	27260156	EW8	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.4184598161467097	[40]	[24,16,98,24]	7	hSpCas9	negative selection	6467864
29216590	29216613	1	+	27260156	EW8	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.0943254400662703	[179]	[251,160,139,82]	1	hSpCas9	negative selection	6467865
29216587	29216610	1	-	27260156	EW8	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.7116855461473961	[663]	[524,269,274,273]	-8	hSpCas9	negative selection	6467866
29206888	29206911	1	-	27260156	CORL105	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.2542448673482818	[155]	[172,229,265,207]	5	hSpCas9	negative selection	6524857
29206833	29206856	1	+	27260156	CORL105	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.046541759634426194	[1023]	[983,1201,1447,1046]	-1	hSpCas9	negative selection	6524858
29216077	29216100	1	-	27260156	CORL105	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.16956177536089578	[113]	[107,102,90,167]	-3	hSpCas9	negative selection	6524859
29216088	29216111	1	+	27260156	CORL105	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.5832005646469489	[40]	[50,80,73,80]	9	hSpCas9	negative selection	6589115
29216590	29216613	1	+	27260156	CORL105	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.5413454335554019	[179]	[311,318,377,228]	8	hSpCas9	negative selection	6589116
29216587	29216610	1	-	27260156	CORL105	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.4264086144404981	[663]	[530,538,532,701]	-7	hSpCas9	negative selection	6589117
29206888	29206911	1	-	27260156	HS294T	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.1773446148387796	[155]	[22,50,69,75]	-2	hSpCas9	negative selection	6646108
29206833	29206856	1	+	27260156	HS294T	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.3808386268924514	[1023]	[265,186,375,411]	-5	hSpCas9	negative selection	6646109
29216077	29216100	1	-	27260156	HS294T	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.09180658758346238	[113]	[56,37,31,35]	-1	hSpCas9	negative selection	6646110
29216088	29216111	1	+	27260156	HS294T	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.13206215555934575	[40]	[11,8,18,18]	-2	hSpCas9	negative selection	6710366
29216590	29216613	1	+	27260156	HS294T	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.34283574400640937	[179]	[83,101,96,65]	4	hSpCas9	negative selection	6710367
29216587	29216610	1	-	27260156	HS294T	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-1.2398913798609938	[663]	[84,78,123,157]	-9	hSpCas9	negative selection	6710368
29206888	29206911	1	-	27260156	HCC44	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.2003871428429833	[155]	[294,165,145,205]	3	hSpCas9	negative selection	6767359
29206833	29206856	1	+	27260156	HCC44	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.06392345661836529	[1023]	[1254,1038,1384,1211]	1	hSpCas9	negative selection	6767360
29216077	29216100	1	-	27260156	HCC44	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.24010069483207763	[113]	[261,60,77,214]	4	hSpCas9	negative selection	6767361
29216088	29216111	1	+	27260156	HCC44	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.7222012715025499	[40]	[187,64,25,30]	9	hSpCas9	negative selection	6831617
29216590	29216613	1	+	27260156	HCC44	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.6207595668017363	[179]	[377,295,461,152]	8	hSpCas9	negative selection	6831618
29216587	29216610	1	-	27260156	HCC44	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.6205835907359233	[663]	[491,310,738,476]	-7	hSpCas9	negative selection	6831619
29206888	29206911	1	-	27260156	G402	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.7162546919419293	[155]	[23,177,106,142]	-7	hSpCas9	negative selection	6888610
29206833	29206856	1	+	27260156	G402	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.5252563723471292	[1023]	[855,855,697,1047]	-6	hSpCas9	negative selection	6888611
29216077	29216100	1	-	27260156	G402	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.4472213089307506	[113]	[197,176,376,14]	5	hSpCas9	negative selection	6888612
29216088	29216111	1	+	27260156	G402	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.5483205591139062	[40]	[87,32,22,1]	-6	hSpCas9	negative selection	6952868
29216590	29216613	1	+	27260156	G402	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.15661376302482388	[179]	[287,243,344,113]	2	hSpCas9	negative selection	6952869
29216587	29216610	1	-	27260156	G402	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-1.2525797403894208	[663]	[273,586,211,292]	-8	hSpCas9	negative selection	6952870
29206888	29206911	1	-	27260156	L33	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.05970992476952608	[155]	[161,72,131,100]	1	hSpCas9	negative selection	7009861
29206833	29206856	1	+	27260156	L33	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.25896823172680183	[1023]	[1227,511,751,1226]	5	hSpCas9	negative selection	7009862
29216077	29216100	1	-	27260156	L33	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.46214784408583154	[113]	[171,65,60,196]	8	hSpCas9	negative selection	7009863
29216088	29216111	1	+	27260156	L33	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.592066463215775	[40]	[73,33,19,57]	9	hSpCas9	negative selection	7074119
29216590	29216613	1	+	27260156	L33	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.22400011718101753	[179]	[221,72,142,212]	5	hSpCas9	negative selection	7074120
29216587	29216610	1	-	27260156	L33	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.4065935088444378	[663]	[502,194,311,527]	-7	hSpCas9	negative selection	7074121
29206888	29206911	1	-	27260156	K562	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.17301770487476253	[155]	[97,199,140,60]	-2	hSpCas9	negative selection	7131112
29206833	29206856	1	+	27260156	K562	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.21711349995977058	[1023]	[963,1542,696,1036]	2	hSpCas9	negative selection	7131113
29216077	29216100	1	-	27260156	K562	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.6438125869720639	[113]	[58,88,22,85]	-6	hSpCas9	negative selection	7131114
29216088	29216111	1	+	27260156	K562	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-2.5970129450931867	[40]	[0,20,1,0]	-9	hSpCas9	negative selection	7195370
29216590	29216613	1	+	27260156	K562	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	1.0150230880530189	[179]	[437,119,476,260]	9	hSpCas9	negative selection	7195371
29216587	29216610	1	-	27260156	K562	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-1.741328101649486	[663]	[221,149,133,197]	-9	hSpCas9	negative selection	7195372
29206888	29206911	1	-	27260156	HT29	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.24372615662668573	[155]	[277,307,179,150]	5	hSpCas9	negative selection	7252363
29206833	29206856	1	+	27260156	HT29	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.4494598894149904	[1023]	[1926,1855,1759,1321]	8	hSpCas9	negative selection	7252364
29216077	29216100	1	-	27260156	HT29	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.05414570499191962	[113]	[199,96,153,125]	1	hSpCas9	negative selection	7252365
29216088	29216111	1	+	27260156	HT29	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.05384055946683519	[40]	[59,47,30,52]	-1	hSpCas9	negative selection	7316621
29216590	29216613	1	+	27260156	HT29	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.9396370306811218	[179]	[491,543,272,386]	9	hSpCas9	negative selection	7316622
29216587	29216610	1	-	27260156	HT29	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.07439728665934314	[663]	[915,657,677,805]	-1	hSpCas9	negative selection	7316623
29206888	29206911	1	-	27260156	MHHES1	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.1634460275412717	[155]	[112,226,191,105]	-3	hSpCas9	negative selection	7373614
29206833	29206856	1	+	27260156	MHHES1	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.18185212991257482	[1023]	[936,1041,882,1142]	-3	hSpCas9	negative selection	7373615
29216077	29216100	1	-	27260156	MHHES1	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.6542034411208046	[113]	[390,308,82,81]	9	hSpCas9	negative selection	7373616
29216088	29216111	1	+	27260156	MHHES1	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.3996758357851169	[40]	[46,18,52,22]	-6	hSpCas9	negative selection	7437872
29216590	29216613	1	+	27260156	MHHES1	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.7141506743990345	[179]	[299,357,258,389]	9	hSpCas9	negative selection	7437873
29216587	29216610	1	-	27260156	MHHES1	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.6308437044350124	[663]	[750,477,512,262]	-8	hSpCas9	negative selection	7437874
29206888	29206911	1	-	27260156	MEWO	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.30133932919827666	[155]	[144,129,257]	6	hSpCas9	negative selection	7494865
29206833	29206856	1	+	27260156	MEWO	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.45561616097929525	[1023]	[1694,1095,1224]	8	hSpCas9	negative selection	7494866
29216077	29216100	1	-	27260156	MEWO	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.9717486357195746	[113]	[58,59,44]	-9	hSpCas9	negative selection	7494867
29216088	29216111	1	+	27260156	MEWO	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.329282103448417	[40]	[37,36,17]	-6	hSpCas9	negative selection	7559123
29216590	29216613	1	+	27260156	MEWO	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.34010948357062243	[179]	[229,156,255]	7	hSpCas9	negative selection	7559124
29216587	29216610	1	-	27260156	MEWO	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.35440215226446853	[663]	[599,428,450]	-6	hSpCas9	negative selection	7559125
29206888	29206911	1	-	27260156	LNCAPCLONEFGC	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.10177005379587278	[155]	[108,128,149,141]	-2	hSpCas9	negative selection	7616116
29206833	29206856	1	+	27260156	LNCAPCLONEFGC	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.03909630333159653	[1023]	[922,777,1000,930]	0	hSpCas9	negative selection	7616117
29216077	29216100	1	-	27260156	LNCAPCLONEFGC	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.0854422601100695	[113]	[141,51,133,116]	1	hSpCas9	negative selection	7616118
29216088	29216111	1	+	27260156	LNCAPCLONEFGC	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.20874446513442058	[40]	[28,24,24,48]	-3	hSpCas9	negative selection	7680374
29216590	29216613	1	+	27260156	LNCAPCLONEFGC	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.7931470974241286	[179]	[207,327,319,277]	9	hSpCas9	negative selection	7680375
29216587	29216610	1	-	27260156	LNCAPCLONEFGC	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.3021460008471053	[663]	[537,416,509,492]	-5	hSpCas9	negative selection	7680376
29206888	29206911	1	-	27260156	PANC0327	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.10814667296867486	[155]	[71,250,160,93]	1	hSpCas9	negative selection	7737367
29206833	29206856	1	+	27260156	PANC0327	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.008466343667663523	[1023]	[796,937,936,974]	0	hSpCas9	negative selection	7737368
29216077	29216100	1	-	27260156	PANC0327	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.9734187965512111	[113]	[252,85,95,378]	9	hSpCas9	negative selection	7737369
29216088	29216111	1	+	27260156	PANC0327	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.0215781627607039	[40]	[23,11,36,76]	0	hSpCas9	negative selection	7801625
29216590	29216613	1	+	27260156	PANC0327	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.756980600387576	[179]	[159,352,248,298]	9	hSpCas9	negative selection	7801626
29216587	29216610	1	-	27260156	PANC0327	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.27241975953116	[663]	[615,568,310,456]	-4	hSpCas9	negative selection	7801627
29206888	29206911	1	-	27260156	NCIH2009	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.04080272847658217	[155]	[423,167,85]	0	hSpCas9	negative selection	7858618
29206833	29206856	1	+	27260156	NCIH2009	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.3241204535622577	[1023]	[1413,927,1141]	-4	hSpCas9	negative selection	7858619
29216077	29216100	1	-	27260156	NCIH2009	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.11458999657498081	[113]	[191,166,161]	1	hSpCas9	negative selection	7858620
29216088	29216111	1	+	27260156	NCIH2009	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	1.138626637669506	[40]	[39,22,299]	9	hSpCas9	negative selection	7922876
29216590	29216613	1	+	27260156	NCIH2009	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	-0.03940008671422257	[179]	[279,172,288]	0	hSpCas9	negative selection	7922877
29216587	29216610	1	-	27260156	NCIH2009	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.40470214794648096	[663]	[787,557,774]	-5	hSpCas9	negative selection	7922878
29206888	29206911	1	-	27260156	NCIH1373	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.24027695894568124	[155]	[304,51,117,39]	-2	hSpCas9	negative selection	7979869
29206833	29206856	1	+	27260156	NCIH1373	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.06946712878440797	[1023]	[2086,950,682,212]	0	hSpCas9	negative selection	7979870
29216077	29216100	1	-	27260156	NCIH1373	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.13434005642924052	[113]	[100,234,50,41]	1	hSpCas9	negative selection	7979871
29216088	29216111	1	+	27260156	NCIH1373	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	1.0879508938048819	[40]	[297,12,60,14]	9	hSpCas9	negative selection	8044127
29216590	29216613	1	+	27260156	NCIH1373	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.3949935589527316	[179]	[201,525,185,25]	4	hSpCas9	negative selection	8044128
29216587	29216610	1	-	27260156	NCIH1373	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.6322158658947887	[663]	[796,429,354,101]	-6	hSpCas9	negative selection	8044129
29206888	29206911	1	-	27260156	PATU8902	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.5031044148312251	[155]	[205,508,255,268]	5	hSpCas9	negative selection	8101120
29206833	29206856	1	+	27260156	PATU8902	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.03892867961872648	[1023]	[2072,1921,661,1021]	0	hSpCas9	negative selection	8101121
29216077	29216100	1	-	27260156	PATU8902	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.3555770433609946	[113]	[102,153,138,91]	-4	hSpCas9	negative selection	8101122
29216088	29216111	1	+	27260156	PATU8902	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.4746655190456006	[40]	[35,5,99,1]	-5	hSpCas9	negative selection	8165378
29216590	29216613	1	+	27260156	PATU8902	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.8960794762237141	[179]	[399,554,183,842]	8	hSpCas9	negative selection	8165379
29216587	29216610	1	-	27260156	PATU8902	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.03960764571603531	[663]	[621,1473,668,890]	0	hSpCas9	negative selection	8165380
29206888	29206911	1	-	27260156	PANC1	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.85156900408853	[155]	[39,81,79,92]	-8	hSpCas9	negative selection	8222371
29206833	29206856	1	+	27260156	PANC1	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.00027622511559788343	[1023]	[844,1095,933,702]	0	hSpCas9	negative selection	8222372
29216077	29216100	1	-	27260156	PANC1	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.3199528657805173	[113]	[78,100,78,60]	-5	hSpCas9	negative selection	8222373
29216088	29216111	1	+	27260156	PANC1	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.2845220337895724	[40]	[56,84,34,7]	4	hSpCas9	negative selection	8286629
29216590	29216613	1	+	27260156	PANC1	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.54566299371122	[179]	[242,280,183,204]	8	hSpCas9	negative selection	8286630
29216587	29216610	1	-	27260156	PANC1	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.36021259472286765	[663]	[455,527,410,398]	-5	hSpCas9	negative selection	8286631
29206888	29206911	1	-	27260156	PANC0813	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.5641481746453889	[155]	[382,302,153,253]	8	hSpCas9	negative selection	8343622
29206833	29206856	1	+	27260156	PANC0813	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.14575395592506635	[1023]	[1258,951,1046,1103]	-2	hSpCas9	negative selection	8343623
29216077	29216100	1	-	27260156	PANC0813	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.15254690918469826	[113]	[72,163,97,140]	-2	hSpCas9	negative selection	8343624
29216088	29216111	1	+	27260156	PANC0813	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.6725010106563691	[40]	[53,17,3,45]	-7	hSpCas9	negative selection	8407880
29216590	29216613	1	+	27260156	PANC0813	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.1956249263083718	[179]	[231,189,293,250]	3	hSpCas9	negative selection	8407881
29216587	29216610	1	-	27260156	PANC0813	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.3153733671566029	[663]	[859,663,606,408]	-5	hSpCas9	negative selection	8407882
29206888	29206911	1	-	27260156	RDES	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.38112331021263013	[155]	[197,233,213,297]	6	hSpCas9	negative selection	8464873
29206833	29206856	1	+	27260156	RDES	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.06600297079033579	[1023]	[926,1028,1044,1583]	-1	hSpCas9	negative selection	8464874
29216077	29216100	1	-	27260156	RDES	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.3534022241216406	[113]	[226,88,154,189]	5	hSpCas9	negative selection	8464875
29216088	29216111	1	+	27260156	RDES	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.07855952715796999	[40]	[32,26,84,36]	-1	hSpCas9	negative selection	8529131
29216590	29216613	1	+	27260156	RDES	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.7825602735137158	[179]	[248,435,318,435]	9	hSpCas9	negative selection	8529132
29216587	29216610	1	-	27260156	RDES	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.27845897028652195	[663]	[418,689,683,770]	-5	hSpCas9	negative selection	8529133
29206888	29206911	1	-	27260156	PC3	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.12151683778792921	[155]	[85,147,266,240]	2	hSpCas9	negative selection	8586124
29206833	29206856	1	+	27260156	PC3	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.4701583416601842	[1023]	[832,1559,2193,1489]	8	hSpCas9	negative selection	8586125
29216077	29216100	1	-	27260156	PC3	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.7146385702068865	[113]	[48,50,62,115]	-9	hSpCas9	negative selection	8586126
29216088	29216111	1	+	27260156	PC3	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.2725762975815176	[40]	[25,46,136,26]	6	hSpCas9	negative selection	8650382
29216590	29216613	1	+	27260156	PC3	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.3642710157572391	[179]	[195,238,370,153]	7	hSpCas9	negative selection	8650383
29216587	29216610	1	-	27260156	PC3	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.6501590728299651	[663]	[304,292,630,557]	-9	hSpCas9	negative selection	8650384
29206888	29206911	1	-	27260156	PATU8988T	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-1.2019172969696776	[155]	[25,68,41,130]	-9	hSpCas9	negative selection	8707375
29206833	29206856	1	+	27260156	PATU8988T	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.5376923398353081	[1023]	[715,811,664,533]	-7	hSpCas9	negative selection	8707376
29216077	29216100	1	-	27260156	PATU8988T	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.3494565363884299	[113]	[176,137,131,111]	6	hSpCas9	negative selection	8707377
29216088	29216111	1	+	27260156	PATU8988T	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.6264605958483549	[40]	[25,43,4,29]	-7	hSpCas9	negative selection	8771633
29216590	29216613	1	+	27260156	PATU8988T	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.4762991453957218	[179]	[231,382,180,180]	7	hSpCas9	negative selection	8771634
29216587	29216610	1	-	27260156	PATU8988T	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.9536722473032919	[663]	[228,375,180,563]	-8	hSpCas9	negative selection	8771635
29206888	29206911	1	-	27260156	T47D	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.14586574737371527	[155]	[208,213,188,190]	3	hSpCas9	negative selection	8828626
29206833	29206856	1	+	27260156	T47D	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.09153118359695989	[1023]	[1348,1179,1186,1380]	2	hSpCas9	negative selection	8828627
29216077	29216100	1	-	27260156	T47D	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.12439116377367432	[113]	[108,82,130,168]	-3	hSpCas9	negative selection	8828628
29216088	29216111	1	+	27260156	T47D	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.1523684791222033	[40]	[49,56,21,41]	-3	hSpCas9	negative selection	8892884
29216590	29216613	1	+	27260156	T47D	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.89271702322891	[179]	[403,370,430,350]	9	hSpCas9	negative selection	8892885
29216587	29216610	1	-	27260156	T47D	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.5769561908847274	[663]	[478,509,503,583]	-8	hSpCas9	negative selection	8892886
29206888	29206911	1	-	27260156	SU8686	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.439692263801156	[155]	[66,123,139,131]	-6	hSpCas9	negative selection	8949877
29206833	29206856	1	+	27260156	SU8686	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.02116442061637258	[1023]	[947,843,986,1431]	0	hSpCas9	negative selection	8949878
29216077	29216100	1	-	27260156	SU8686	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.4789555433378465	[113]	[110,143,174,215]	7	hSpCas9	negative selection	8949879
29216088	29216111	1	+	27260156	SU8686	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.16917683579405018	[40]	[29,28,60,70]	3	hSpCas9	negative selection	9014135
29216590	29216613	1	+	27260156	SU8686	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.6939081317130725	[179]	[217,250,373,331]	9	hSpCas9	negative selection	9014136
29216587	29216610	1	-	27260156	SU8686	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.062175251533703235	[663]	[552,583,595,830]	-1	hSpCas9	negative selection	9014137
29206888	29206911	1	-	27260156	SKES1	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.15960598296472894	[155]	[170,191,142,68]	-3	hSpCas9	negative selection	9071128
29206833	29206856	1	+	27260156	SKES1	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.2834084768751841	[1023]	[1650,1257,1141,997]	6	hSpCas9	negative selection	9071129
29216077	29216100	1	-	27260156	SKES1	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.16687041945224212	[113]	[120,83,110,89]	-4	hSpCas9	negative selection	9071130
29216088	29216111	1	+	27260156	SKES1	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.23538112318714077	[40]	[41,7,109,27]	5	hSpCas9	negative selection	9135386
29216590	29216613	1	+	27260156	SKES1	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.21187023475254096	[179]	[204,190,212,216]	4	hSpCas9	negative selection	9135387
29216587	29216610	1	-	27260156	SKES1	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.45365807138476905	[663]	[554,514,438,439]	-7	hSpCas9	negative selection	9135388
29206888	29206911	1	-	27260156	TOV112D	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.12277010009738576	[155]	[102,206,180,191]	2	hSpCas9	negative selection	9192379
29206833	29206856	1	+	27260156	TOV112D	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.06667255554925244	[1023]	[971,1092,940,937]	-1	hSpCas9	negative selection	9192380
29216077	29216100	1	-	27260156	TOV112D	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	-0.2703761429544005	[113]	[147,71,83,73]	-5	hSpCas9	negative selection	9192381
29216088	29216111	1	+	27260156	TOV112D	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-1.2283518001965184	[40]	[21,18,18,10]	-9	hSpCas9	negative selection	9256637
29216590	29216613	1	+	27260156	TOV112D	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.6453989270223397	[179]	[224,253,180,450]	9	hSpCas9	negative selection	9256638
29216587	29216610	1	-	27260156	TOV112D	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.3404505201237087	[663]	[570,496,576,453]	-6	hSpCas9	negative selection	9256639
29206888	29206911	1	-	27260156	TC71	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	-0.22110204870435557	[155]	[130,216,94,131]	-5	hSpCas9	negative selection	9313630
29206833	29206856	1	+	27260156	TC71	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	0.18485381983402016	[1023]	[1133,1197,1348,1312]	4	hSpCas9	negative selection	9313631
29216077	29216100	1	-	27260156	TC71	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.16049662048229596	[113]	[128,71,108,243]	4	hSpCas9	negative selection	9313632
29216088	29216111	1	+	27260156	TC71	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	0.03990515803988792	[40]	[28,79,53,15]	1	hSpCas9	negative selection	9377888
29216590	29216613	1	+	27260156	TC71	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.43225265410650315	[179]	[190,353,234,263]	8	hSpCas9	negative selection	9377889
29216587	29216610	1	-	27260156	TC71	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.5483335209929118	[663]	[421,422,563,539]	-9	hSpCas9	negative selection	9377890
29206888	29206911	1	-	27260156	TC32	viability	CTCAGGAACCTGGCGGACCGAGG	MECR	ENSG00000116353	0.1543737225239552	[155]	[138,111,186,235]	3	hSpCas9	negative selection	9434881
29206833	29206856	1	+	27260156	TC32	viability	CTCTGAAGAGGGATGTCACTCGG	MECR	ENSG00000116353	-0.0795899364385464	[1023]	[850,635,1060,1194]	-1	hSpCas9	negative selection	9434882
29216077	29216100	1	-	27260156	TC32	viability	AGGGAACGAAGGTGTTGCACAGG	MECR	ENSG00000116353	0.6311797953221536	[113]	[131,179,204,139]	9	hSpCas9	negative selection	9434883
29216088	29216111	1	+	27260156	TC32	viability	CCTTCGTTCCCTCCAACAGCAGG	MECR	ENSG00000116353	-0.013164642156370476	[40]	[23,45,44,34]	0	hSpCas9	negative selection	9499139
29216590	29216613	1	+	27260156	TC32	viability	TGGATCATATTTATGTCAGATGG	MECR	ENSG00000116353	0.7723929662826559	[179]	[295,277,312,254]	9	hSpCas9	negative selection	9499140
29216587	29216610	1	-	27260156	TC32	viability	TCTGACATAAATATGATCCAAGG	MECR	ENSG00000116353	-0.3584829058354149	[663]	[439,556,497,393]	-6	hSpCas9	negative selection	9499141
29196193	29196216	1	+	27869803	HPAFII	viability after 27 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-1.8727151074497428	[555]	[105,57,NaN]	-8	hSpCas9	negative selection	9533679
29203195	29203218	1	-	27869803	HPAFII	viability after 27 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-1.5406750146486	[163]	[63,0,NaN]	-7	hSpCas9	negative selection	9533680
29206873	29206896	1	-	27869803	HPAFII	viability after 27 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-2.157685946398278	[357]	[27,53,NaN]	-8	hSpCas9	negative selection	9533681
29216065	29216088	1	-	27869803	HPAFII	viability after 27 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-3.444388323011254	[511]	[15,31,NaN]	-9	hSpCas9	negative selection	9533682
29216621	29216644	1	+	27869803	HPAFII	viability after 27 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-1.7195470262322563	[290]	[22,65,NaN]	-8	hSpCas9	negative selection	9533683
29230762	29230785	1	+	27869803	HPAFII	viability after 27 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	0.24781888085885073	[465]	[399,199,NaN]	2	hSpCas9	negative selection	9533684
29196193	29196216	1	+	27869803	HPAFII	viability after 15 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-0.02762358667184217	[555]	[592,581,NaN]	0	hSpCas9	negative selection	9616128
29203195	29203218	1	-	27869803	HPAFII	viability after 15 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.1263726959378294	[163]	[232,116,NaN]	-1	hSpCas9	negative selection	9616129
29206873	29206896	1	-	27869803	HPAFII	viability after 15 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	0.26045684924005386	[357]	[598,374,NaN]	3	hSpCas9	negative selection	9616130
29216065	29216088	1	-	27869803	HPAFII	viability after 15 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-0.3889764207081412	[511]	[619,295,NaN]	-4	hSpCas9	negative selection	9616131
29216621	29216644	1	+	27869803	HPAFII	viability after 15 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.43861308157288476	[290]	[313,178,NaN]	-5	hSpCas9	negative selection	9616132
29230762	29230785	1	+	27869803	HPAFII	viability after 15 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	-0.018261555578780175	[465]	[578,441,NaN]	0	hSpCas9	negative selection	9616133
29196193	29196216	1	+	27869803	ASPC1	viability after 36 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	0.3936962742625336	[1150]	[401,680,488]	4	hSpCas9	negative selection	9698577
29203195	29203218	1	-	27869803	ASPC1	viability after 36 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.042383782830637484	[323]	[249,45,60]	0	hSpCas9	negative selection	9698578
29206873	29206896	1	-	27869803	ASPC1	viability after 36 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-0.4569102999593019	[870]	[248,204,212]	-5	hSpCas9	negative selection	9698579
29216065	29216088	1	-	27869803	ASPC1	viability after 36 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-0.4764081427571911	[1270]	[498,235,254]	-5	hSpCas9	negative selection	9698580
29216621	29216644	1	+	27869803	ASPC1	viability after 36 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	0.5821777431925057	[607]	[313,672,34]	6	hSpCas9	negative selection	9698581
29230762	29230785	1	+	27869803	ASPC1	viability after 36 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	0.9609526806145512	[880]	[609,549,622]	8	hSpCas9	negative selection	9698582
29196193	29196216	1	+	27869803	PATU8988S	viability after 35 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	0.1922490273777716	[893]	[578,242,NaN]	2	hSpCas9	negative selection	9781026
29203195	29203218	1	-	27869803	PATU8988S	viability after 35 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.3513334733175868	[352]	[85,136,NaN]	-4	hSpCas9	negative selection	9781027
29206873	29206896	1	-	27869803	PATU8988S	viability after 35 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	0.04789612076090388	[1176]	[506,472,NaN]	0	hSpCas9	negative selection	9781028
29216065	29216088	1	-	27869803	PATU8988S	viability after 35 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	0.5478108818931543	[1066]	[721,533,NaN]	6	hSpCas9	negative selection	9781029
29216621	29216644	1	+	27869803	PATU8988S	viability after 35 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.5378830263162002	[594]	[189,139,NaN]	-5	hSpCas9	negative selection	9781030
29230762	29230785	1	+	27869803	PATU8988S	viability after 35 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	-0.0864422586625283	[1053]	[316,482,NaN]	-1	hSpCas9	negative selection	9781031
29196193	29196216	1	+	27869803	PATU8988S	viability after 31 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	0.2804384961475773	[893]	[450,409,NaN]	3	hSpCas9	negative selection	9863475
29203195	29203218	1	-	27869803	PATU8988S	viability after 31 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.6823172585086011	[352]	[59,122,NaN]	-6	hSpCas9	negative selection	9863476
29206873	29206896	1	-	27869803	PATU8988S	viability after 31 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	0.20018338625867682	[1176]	[426,681,NaN]	2	hSpCas9	negative selection	9863477
29216065	29216088	1	-	27869803	PATU8988S	viability after 31 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	0.17000026372747412	[1066]	[413,560,NaN]	2	hSpCas9	negative selection	9863478
29216621	29216644	1	+	27869803	PATU8988S	viability after 31 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-0.1426336933765677	[594]	[206,224,NaN]	-2	hSpCas9	negative selection	9863479
29230762	29230785	1	+	27869803	PATU8988S	viability after 31 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	-0.4348209684592027	[1053]	[280,348,NaN]	-5	hSpCas9	negative selection	9863480
29196193	29196216	1	+	27869803	HPAFII	viability after 35 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-2.5827490562414726	[555]	[14,82,NaN]	-8	hSpCas9	negative selection	9945924
29203195	29203218	1	-	27869803	HPAFII	viability after 35 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-3.303174590814529	[163]	[6,9,NaN]	-8	hSpCas9	negative selection	9945925
29206873	29206896	1	-	27869803	HPAFII	viability after 35 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-2.355759848106194	[357]	[25,45,NaN]	-8	hSpCas9	negative selection	9945926
29216065	29216088	1	-	27869803	HPAFII	viability after 35 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-8.017911447003325	[511]	[0,0,NaN]	-9	hSpCas9	negative selection	9945927
29216621	29216644	1	+	27869803	HPAFII	viability after 35 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-2.2734523519188232	[290]	[29,30,NaN]	-8	hSpCas9	negative selection	9945928
29230762	29230785	1	+	27869803	HPAFII	viability after 35 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	-0.37217397401568986	[465]	[249,105,NaN]	-2	hSpCas9	negative selection	9945929
29196193	29196216	1	+	27869803	HPAFII	viability after 31 days	CTTACCACAGAGGCTACGACGGG	MECR	ENSG00000116353	-2.3912717813701874	[555]	[58,59,NaN]	-8	hSpCas9	negative selection	10028373
29203195	29203218	1	-	27869803	HPAFII	viability after 31 days	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-3.320308471577176	[163]	[13,3,NaN]	-9	hSpCas9	negative selection	10028374
29206873	29206896	1	-	27869803	HPAFII	viability after 31 days	GACCGAGGCTGTGTTCAGCGAGG	MECR	ENSG00000116353	-1.802089904128089	[357]	[48,66,NaN]	-7	hSpCas9	negative selection	10028375
29216065	29216088	1	-	27869803	HPAFII	viability after 31 days	TGTTGCACAGGTGGTAGCGGTGG	MECR	ENSG00000116353	-4.555287772780295	[511]	[5,18,NaN]	-9	hSpCas9	negative selection	10028376
29216621	29216644	1	+	27869803	HPAFII	viability after 31 days	GGGCCGCCAGCATCTTCACACGG	MECR	ENSG00000116353	-1.7113625186252392	[290]	[46,52,NaN]	-7	hSpCas9	negative selection	10028377
29230762	29230785	1	+	27869803	HPAFII	viability after 31 days	CATAGACAAGCGCCCGGACCCGG	MECR	ENSG00000116353	0.07905301185671232	[465]	[348,196,NaN]	0	hSpCas9	negative selection	10028378
29206805	29206828	1	+	28162770	P31FUJ	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-2.370305728164314	[131]	[29]	-8	hSpCas9	negative selection	10190562
29195960	29195983	1	-	28162770	P31FUJ	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-1.1024941820686476	[401]	[219]	-6	hSpCas9	negative selection	10190563
29206778	29206801	1	+	28162770	P31FUJ	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-0.5022628794076054	[539]	[447]	-4	hSpCas9	negative selection	10190564
29200555	29200578	1	+	28162770	P31FUJ	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-0.169026293981064	[176]	[184]	-2	hSpCas9	negative selection	10190565
29196192	29196215	1	+	28162770	P31FUJ	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	0.391688660493415	[143]	[221]	4	hSpCas9	negative selection	10190566
29216624	29216647	1	-	28162770	P31FUJ	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.7583436188759872	[546]	[379]	-5	hSpCas9	negative selection	10190567
29203195	29203218	1	-	28162770	P31FUJ	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.43443606558402925	[229]	[199]	-4	hSpCas9	negative selection	10190568
29201978	29202001	1	-	28162770	P31FUJ	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-0.7140907855320644	[556]	[398]	-5	hSpCas9	negative selection	10190569
29200524	29200547	1	-	28162770	P31FUJ	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	-0.44692700976722577	[86]	[74]	-4	hSpCas9	negative selection	10190570
29196232	29196255	1	-	28162770	P31FUJ	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-0.40456855268085856	[293]	[260]	-4	hSpCas9	negative selection	10190571
29206805	29206828	1	+	28162770	TF1	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10359928
29195960	29195983	1	-	28162770	TF1	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	NaN	[NaN]	[136]	1	hSpCas9	negative selection	10359929
29206778	29206801	1	+	28162770	TF1	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	NaN	[NaN]	[118]	1	hSpCas9	negative selection	10359930
29200555	29200578	1	+	28162770	TF1	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	NaN	[NaN]	[33]	1	hSpCas9	negative selection	10359931
29196192	29196215	1	+	28162770	TF1	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10359932
29216624	29216647	1	-	28162770	TF1	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	NaN	[NaN]	[141]	1	hSpCas9	negative selection	10359933
29203195	29203218	1	-	28162770	TF1	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10359934
29201978	29202001	1	-	28162770	TF1	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	NaN	[NaN]	[131]	1	hSpCas9	negative selection	10359935
29200524	29200547	1	-	28162770	TF1	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10359936
29196232	29196255	1	-	28162770	TF1	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10359937
29206805	29206828	1	+	28162770	SKM1	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-1.4349785749127584	[25]	[16]	-7	hSpCas9	negative selection	10529294
29195960	29195983	1	-	28162770	SKM1	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-0.8220016980220057	[110]	[110]	-6	hSpCas9	negative selection	10529295
29206778	29206801	1	+	28162770	SKM1	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-1.1567919438464174	[168]	[133]	-7	hSpCas9	negative selection	10529296
29200555	29200578	1	+	28162770	SKM1	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-0.1044014287227304	[44]	[73]	-1	hSpCas9	negative selection	10529297
29196192	29196215	1	+	28162770	SKM1	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	-1.7675539139996292	[51]	[26]	-8	hSpCas9	negative selection	10529298
29216624	29216647	1	-	28162770	SKM1	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.603821527972472	[146]	[170]	-5	hSpCas9	negative selection	10529299
29203195	29203218	1	-	28162770	SKM1	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	0.23163626558006772	[65]	[136]	2	hSpCas9	negative selection	10529300
29201978	29202001	1	-	28162770	SKM1	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-1.192113326419333	[136]	[105]	-7	hSpCas9	negative selection	10529301
29200524	29200547	1	-	28162770	SKM1	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	-0.3563381256731937	[20]	[28]	-3	hSpCas9	negative selection	10529302
29196232	29196255	1	-	28162770	SKM1	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-1.41761144294267	[67]	[44]	-7	hSpCas9	negative selection	10529303
29206805	29206828	1	+	28162770	SKM1	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-1.4349785749127584	[25]	[16]	-7	hSpCas9	negative selection	10698660
29195960	29195983	1	-	28162770	SKM1	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-0.8220016980220057	[110]	[110]	-6	hSpCas9	negative selection	10698661
29206778	29206801	1	+	28162770	SKM1	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-1.1567919438464174	[168]	[133]	-7	hSpCas9	negative selection	10698662
29200555	29200578	1	+	28162770	SKM1	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-0.1044014287227304	[44]	[73]	-1	hSpCas9	negative selection	10698663
29196192	29196215	1	+	28162770	SKM1	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	-1.7675539139996292	[51]	[26]	-8	hSpCas9	negative selection	10698664
29216624	29216647	1	-	28162770	SKM1	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.603821527972472	[146]	[170]	-5	hSpCas9	negative selection	10698665
29203195	29203218	1	-	28162770	SKM1	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	0.23163626558006772	[65]	[136]	2	hSpCas9	negative selection	10698666
29201978	29202001	1	-	28162770	SKM1	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-1.192113326419333	[136]	[105]	-7	hSpCas9	negative selection	10698667
29200524	29200547	1	-	28162770	SKM1	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	-0.3563381256731937	[20]	[28]	-3	hSpCas9	negative selection	10698668
29196232	29196255	1	-	28162770	SKM1	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-1.41761144294267	[67]	[44]	-7	hSpCas9	negative selection	10698669
29206805	29206828	1	+	28162770	PL21	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-1.6431348818232268	[121]	[16]	-8	hSpCas9	negative selection	10868026
29195960	29195983	1	-	28162770	PL21	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-0.4110885409256416	[387]	[126]	-3	hSpCas9	negative selection	10868027
29206778	29206801	1	+	28162770	PL21	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-0.6656009847653213	[768]	[210]	-5	hSpCas9	negative selection	10868028
29200555	29200578	1	+	28162770	PL21	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-0.38482288623183614	[167]	[55]	-3	hSpCas9	negative selection	10868029
29196192	29196215	1	+	28162770	PL21	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	-1.0250352475184548	[172]	[36]	-6	hSpCas9	negative selection	10868030
29216624	29216647	1	-	28162770	PL21	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.9829979030629408	[712]	[156]	-6	hSpCas9	negative selection	10868031
29203195	29203218	1	-	28162770	PL21	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	0.33974568178490194	[186]	[102]	3	hSpCas9	negative selection	10868032
29201978	29202001	1	-	28162770	PL21	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-0.6573063555845069	[336]	[92]	-4	hSpCas9	negative selection	10868033
29200524	29200547	1	-	28162770	PL21	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	1.4396055491847095	[71]	[84]	9	hSpCas9	negative selection	10868034
29196232	29196255	1	-	28162770	PL21	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	0.46090384669828693	[211]	[126]	4	hSpCas9	negative selection	10868035
29206805	29206828	1	+	28162770	P31FUJ	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-2.370305728164314	[131]	[29]	-8	hSpCas9	negative selection	11037392
29195960	29195983	1	-	28162770	P31FUJ	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-1.1024941820686476	[401]	[219]	-6	hSpCas9	negative selection	11037393
29206778	29206801	1	+	28162770	P31FUJ	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-0.5022628794076054	[539]	[447]	-4	hSpCas9	negative selection	11037394
29200555	29200578	1	+	28162770	P31FUJ	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-0.169026293981064	[176]	[184]	-2	hSpCas9	negative selection	11037395
29196192	29196215	1	+	28162770	P31FUJ	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	0.391688660493415	[143]	[221]	4	hSpCas9	negative selection	11037396
29216624	29216647	1	-	28162770	P31FUJ	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.7583436188759872	[546]	[379]	-5	hSpCas9	negative selection	11037397
29203195	29203218	1	-	28162770	P31FUJ	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.43443606558402925	[229]	[199]	-4	hSpCas9	negative selection	11037398
29201978	29202001	1	-	28162770	P31FUJ	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-0.7140907855320644	[556]	[398]	-5	hSpCas9	negative selection	11037399
29200524	29200547	1	-	28162770	P31FUJ	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	-0.44692700976722577	[86]	[74]	-4	hSpCas9	negative selection	11037400
29196232	29196255	1	-	28162770	P31FUJ	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-0.40456855268085856	[293]	[260]	-4	hSpCas9	negative selection	11037401
29206805	29206828	1	+	28162770	OCIAML5	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-0.8260713623310525	[54]	[55]	-5	hSpCas9	negative selection	11206758
29195960	29195983	1	-	28162770	OCIAML5	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-1.651019051925904	[213]	[122]	-7	hSpCas9	negative selection	11206759
29206778	29206801	1	+	28162770	OCIAML5	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-1.4627391906910485	[367]	[240]	-7	hSpCas9	negative selection	11206760
29200555	29200578	1	+	28162770	OCIAML5	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-0.7094621754211967	[76]	[84]	-5	hSpCas9	negative selection	11206761
29196192	29196215	1	+	28162770	OCIAML5	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	-1.035288394919767	[108]	[95]	-6	hSpCas9	negative selection	11206762
29216624	29216647	1	-	28162770	OCIAML5	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-2.169256746744696	[303]	[121]	-8	hSpCas9	negative selection	11206763
29203195	29203218	1	-	28162770	OCIAML5	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-1.4009598168776314	[157]	[107]	-7	hSpCas9	negative selection	11206764
29201978	29202001	1	-	28162770	OCIAML5	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-0.9715018018526165	[364]	[335]	-6	hSpCas9	negative selection	11206765
29200524	29200547	1	-	28162770	OCIAML5	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	1.139109578748997	[40]	[162]	8	hSpCas9	negative selection	11206766
29196232	29196255	1	-	28162770	OCIAML5	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-1.0434926415172314	[168]	[147]	-6	hSpCas9	negative selection	11206767
29206805	29206828	1	+	28162770	EOL1	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-2.1730630250558876	[213]	[24]	-8	hSpCas9	negative selection	11376124
29195960	29195983	1	-	28162770	EOL1	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-0.7890250041664525	[468]	[142]	-5	hSpCas9	negative selection	11376125
29206778	29206801	1	+	28162770	EOL1	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-0.8471298461694368	[1317]	[385]	-5	hSpCas9	negative selection	11376126
29200555	29200578	1	+	28162770	EOL1	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-2.8588282875526296	[357]	[25]	-9	hSpCas9	negative selection	11376127
29196192	29196215	1	+	28162770	EOL1	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	-0.3533053489748046	[273]	[112]	-3	hSpCas9	negative selection	11376128
29216624	29216647	1	-	28162770	EOL1	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-1.0410692344038017	[1077]	[275]	-6	hSpCas9	negative selection	11376129
29203195	29203218	1	-	28162770	EOL1	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	0.10551104446529519	[216]	[122]	0	hSpCas9	negative selection	11376130
29201978	29202001	1	-	28162770	EOL1	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-1.2101017551242474	[504]	[114]	-7	hSpCas9	negative selection	11376131
29200524	29200547	1	-	28162770	EOL1	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	-1.9141713213964047	[92]	[12]	-8	hSpCas9	negative selection	11376132
29196232	29196255	1	-	28162770	EOL1	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-0.8700285457657668	[280]	[80]	-6	hSpCas9	negative selection	11376133
29206805	29206828	1	+	28162770	MOLM13	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-1.8012972512708103	[187]	[38]	-7	hSpCas9	negative selection	11545490
29195960	29195983	1	-	28162770	MOLM13	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-1.351978151826574	[578]	[163]	-6	hSpCas9	negative selection	11545491
29206778	29206801	1	+	28162770	MOLM13	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-0.30952825635892167	[1084]	[632]	-2	hSpCas9	negative selection	11545492
29200555	29200578	1	+	28162770	MOLM13	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	0.2255285439755348	[193]	[163]	1	hSpCas9	negative selection	11545493
29196192	29196215	1	+	28162770	MOLM13	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	0.3264509770049808	[256]	[232]	2	hSpCas9	negative selection	11545494
29216624	29216647	1	-	28162770	MOLM13	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.3435908031706505	[787]	[448]	-2	hSpCas9	negative selection	11545495
29203195	29203218	1	-	28162770	MOLM13	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-1.5161690745863996	[359]	[90]	-6	hSpCas9	negative selection	11545496
29201978	29202001	1	-	28162770	MOLM13	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-1.0623775983903245	[646]	[223]	-5	hSpCas9	negative selection	11545497
29200524	29200547	1	-	28162770	MOLM13	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	0.4543428497066312	[106]	[105]	3	hSpCas9	negative selection	11545498
29196232	29196255	1	-	28162770	MOLM13	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-0.4984274921991324	[253]	[129]	-3	hSpCas9	negative selection	11545499
29206805	29206828	1	+	28162770	HEL	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-4.205258074554592	[143]	[4]	-9	hSpCas9	negative selection	11714856
29195960	29195983	1	-	28162770	HEL	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-1.6941009722909337	[388]	[76]	-7	hSpCas9	negative selection	11714857
29206778	29206801	1	+	28162770	HEL	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-2.4468983804843196	[995]	[116]	-8	hSpCas9	negative selection	11714858
29200555	29200578	1	+	28162770	HEL	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-3.7180085117775334	[225]	[10]	-9	hSpCas9	negative selection	11714859
29196192	29196215	1	+	28162770	HEL	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	-0.5892078960493399	[201]	[85]	-4	hSpCas9	negative selection	11714860
29216624	29216647	1	-	28162770	HEL	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-3.1744908379923626	[732]	[51]	-9	hSpCas9	negative selection	11714861
29203195	29203218	1	-	28162770	HEL	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-3.237184716007892	[264]	[17]	-9	hSpCas9	negative selection	11714862
29201978	29202001	1	-	28162770	HEL	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-0.8621300775075527	[507]	[178]	-5	hSpCas9	negative selection	11714863
29200524	29200547	1	-	28162770	HEL	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	-0.15081029053221662	[77]	[44]	-1	hSpCas9	negative selection	11714864
29196232	29196255	1	-	28162770	HEL	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-1.9125984996115208	[240]	[40]	-7	hSpCas9	negative selection	11714865
29206805	29206828	1	+	28162770	MV411	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-1.0683383171229919	[116]	[46]	-6	hSpCas9	negative selection	11884222
29195960	29195983	1	-	28162770	MV411	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-0.5971079305832456	[333]	[185]	-4	hSpCas9	negative selection	11884223
29206778	29206801	1	+	28162770	MV411	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-0.7173730207549247	[647]	[331]	-5	hSpCas9	negative selection	11884224
29200555	29200578	1	+	28162770	MV411	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-0.5428438579158874	[146]	[84]	-4	hSpCas9	negative selection	11884225
29196192	29196215	1	+	28162770	MV411	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	-0.15552711619549342	[118]	[89]	-1	hSpCas9	negative selection	11884226
29216624	29216647	1	-	28162770	MV411	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-1.1004857526375318	[503]	[197]	-6	hSpCas9	negative selection	11884227
29203195	29203218	1	-	28162770	MV411	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-1.6821731213258264	[159]	[41]	-8	hSpCas9	negative selection	11884228
29201978	29202001	1	-	28162770	MV411	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-0.6567024338097084	[392]	[209]	-5	hSpCas9	negative selection	11884229
29200524	29200547	1	-	28162770	MV411	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	1.181549615126318	[55]	[106]	9	hSpCas9	negative selection	11884230
29196232	29196255	1	-	28162770	MV411	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-0.8530893251711889	[207]	[96]	-5	hSpCas9	negative selection	11884231
29206805	29206828	1	+	28162770	MONOMAC1	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	0.22784843817563727	[72]	[97]	2	hSpCas9	negative selection	12053588
29195960	29195983	1	-	28162770	MONOMAC1	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	0.5310913838474753	[261]	[433]	5	hSpCas9	negative selection	12053589
29206778	29206801	1	+	28162770	MONOMAC1	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	0.09057558149490585	[484]	[591]	0	hSpCas9	negative selection	12053590
29200555	29200578	1	+	28162770	MONOMAC1	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-0.12524616399154337	[97]	[102]	-1	hSpCas9	negative selection	12053591
29196192	29196215	1	+	28162770	MONOMAC1	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	0.2536245619500116	[89]	[122]	2	hSpCas9	negative selection	12053592
29216624	29216647	1	-	28162770	MONOMAC1	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.6217245163721166	[399]	[297]	-5	hSpCas9	negative selection	12053593
29203195	29203218	1	-	28162770	MONOMAC1	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.6776626879659743	[119]	[85]	-5	hSpCas9	negative selection	12053594
29201978	29202001	1	-	28162770	MONOMAC1	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-0.7466440713327475	[261]	[178]	-6	hSpCas9	negative selection	12053595
29200524	29200547	1	-	28162770	MONOMAC1	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	1.4361808222688237	[48]	[151]	9	hSpCas9	negative selection	12053596
29196232	29196255	1	-	28162770	MONOMAC1	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-0.7631403205293941	[113]	[76]	-6	hSpCas9	negative selection	12053597
29206805	29206828	1	+	28162770	OCIAML2	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-1.5195394257231074	[29]	[57]	-7	hSpCas9	negative selection	12222954
29195960	29195983	1	-	28162770	OCIAML2	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-1.5281153199029214	[63]	[122]	-7	hSpCas9	negative selection	12222955
29206778	29206801	1	+	28162770	OCIAML2	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-0.5904695952481647	[137]	[507]	-4	hSpCas9	negative selection	12222956
29200555	29200578	1	+	28162770	OCIAML2	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-0.7954695155494268	[30]	[98]	-5	hSpCas9	negative selection	12222957
29196192	29196215	1	+	28162770	OCIAML2	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	-1.0763508861301148	[34]	[91]	-6	hSpCas9	negative selection	12222958
29216624	29216647	1	-	28162770	OCIAML2	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.789580220329628	[120]	[387]	-5	hSpCas9	negative selection	12222959
29203195	29203218	1	-	28162770	OCIAML2	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-0.5563596992680453	[38]	[146]	-4	hSpCas9	negative selection	12222960
29201978	29202001	1	-	28162770	OCIAML2	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	-0.855165236123661	[77]	[238]	-5	hSpCas9	negative selection	12222961
29200524	29200547	1	-	28162770	OCIAML2	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	0.28069106190111526	[14]	[100]	2	hSpCas9	negative selection	12222962
29196232	29196255	1	-	28162770	OCIAML2	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-1.375472592201821	[43]	[93]	-7	hSpCas9	negative selection	12222963
29206805	29206828	1	+	28162770	OCIAML3	viability	GCAGGGATTGACACCCAGGGTGG	MECR	ENSG00000116353	-0.3845542746952133	[31]	[73]	-3	hSpCas9	negative selection	12392320
29195960	29195983	1	-	28162770	OCIAML3	viability	GAGGCTTTTGGTTGTCCCAGTGG	MECR	ENSG00000116353	-0.4240826388818509	[91]	[206]	-3	hSpCas9	negative selection	12392321
29206778	29206801	1	+	28162770	OCIAML3	viability	GAAGTCCATCAACATCCTGTAGG	MECR	ENSG00000116353	-0.17677258534107354	[163]	[437]	-1	hSpCas9	negative selection	12392322
29200555	29200578	1	+	28162770	OCIAML3	viability	ACACAGTTGAGAGCAAGCCGTGG	MECR	ENSG00000116353	-0.9445048874082964	[50]	[79]	-6	hSpCas9	negative selection	12392323
29196192	29196215	1	+	28162770	OCIAML3	viability	GCTTACCACAGAGGCTACGACGG	MECR	ENSG00000116353	-1.1442047228846428	[40]	[55]	-7	hSpCas9	negative selection	12392324
29216624	29216647	1	-	28162770	OCIAML3	viability	TGTCCGTGTGAAGATGCTGGCGG	MECR	ENSG00000116353	-0.6884000105991178	[149]	[280]	-5	hSpCas9	negative selection	12392325
29203195	29203218	1	-	28162770	OCIAML3	viability	GAATGCATCCAACAGCGGAGTGG	MECR	ENSG00000116353	-1.226275855823676	[61]	[79]	-7	hSpCas9	negative selection	12392326
29201978	29202001	1	-	28162770	OCIAML3	viability	TGAGCATGTCATCACAGAAGAGG	MECR	ENSG00000116353	0.167832622481072	[114]	[389]	1	hSpCas9	negative selection	12392327
29200524	29200547	1	-	28162770	OCIAML3	viability	AAAGCTCCACAGAGCTGCTGCGG	MECR	ENSG00000116353	-1.352999540820368	[21]	[25]	-7	hSpCas9	negative selection	12392328
29196232	29196255	1	-	28162770	OCIAML3	viability	GGAGGAACCATGGTAACCTATGG	MECR	ENSG00000116353	-0.07943446749440494	[48]	[139]	0	hSpCas9	negative selection	12392329