Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 4221
• Symbol: MEN1
• Description: menin 1

DataSource: http://genomecrispr.dkfz.de/#!/results/MEN1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
64809852	64809875	11	+	26472758	Jiyoye	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	-0.800149591741633	[507]	[219]	-5	hSpCas9	negative selection	98567
64809699	64809722	11	-	26472758	Jiyoye	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-1.0270556830062814	[226]	[83]	-6	hSpCas9	negative selection	98568
64808050	64808073	11	+	26472758	Jiyoye	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	-1.1453656415229054	[219]	[74]	-7	hSpCas9	negative selection	98569
64807978	64808001	11	+	26472758	Jiyoye	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	-0.1832415493073909	[264]	[175]	-1	hSpCas9	negative selection	98570
64807042	64807065	11	-	26472758	Jiyoye	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-2.9026798810809136	[118]	[11]	-9	hSpCas9	negative selection	98571
64805667	64805690	11	-	26472758	Jiyoye	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	5.451569500864326	[0]	[32]	9	hSpCas9	negative selection	98572
64805157	64805180	11	+	26472758	Jiyoye	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	-0.5257104226355898	[20]	[10]	-4	hSpCas9	negative selection	98573
64809935	64809958	11	+	26472758	Jiyoye	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-0.129578026172663	[102]	[70]	-1	hSpCas9	negative selection	98574
64809877	64809900	11	+	26472758	Jiyoye	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	-0.30136180433381554	[133]	[81]	-2	hSpCas9	negative selection	98575
64809828	64809851	11	+	26472758	Jiyoye	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	1.4071753815058727	[0]	[1]	8	hSpCas9	negative selection	98576
64809852	64809875	11	+	26472758	KBM7	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	-0.1835165962604277	[1184,845]	[484,352]	-2	hSpCas9	negative selection	289685
64809699	64809722	11	-	26472758	KBM7	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-1.6961881020757845	[1051,1083]	[118,188]	-8	hSpCas9	negative selection	289686
64808050	64808073	11	+	26472758	KBM7	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	-2.1073552623261804	[644,507]	[53,69]	-8	hSpCas9	negative selection	289687
64807978	64808001	11	+	26472758	KBM7	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	-1.2620786949256608	[1024,681]	[160,167]	-7	hSpCas9	negative selection	289688
64807042	64807065	11	-	26472758	KBM7	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-1.9218478585421113	[633,432]	[69,60]	-8	hSpCas9	negative selection	289689
64805667	64805690	11	-	26472758	KBM7	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	0.15614907181464455	[92,76]	[75,15]	1	hSpCas9	negative selection	289690
64805157	64805180	11	+	26472758	KBM7	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	0.5254573825489572	[105,126]	[127,36]	6	hSpCas9	negative selection	289691
64809935	64809958	11	+	26472758	KBM7	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-0.9353622477856249	[335,568]	[185,50]	-6	hSpCas9	negative selection	289692
64809877	64809900	11	+	26472758	KBM7	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	-0.08553169940912553	[633,483]	[216,270]	-1	hSpCas9	negative selection	289693
64809828	64809851	11	+	26472758	KBM7	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-0.6849485002289546	[38,18]	[3,11]	-5	hSpCas9	negative selection	289694
64809852	64809875	11	+	26472758	Raji	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	-0.5243434326834782	[532]	[85]	-4	hSpCas9	negative selection	480803
64809699	64809722	11	-	26472758	Raji	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-1.9143115357257194	[535]	[32]	-8	hSpCas9	negative selection	480804
64808050	64808073	11	+	26472758	Raji	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	-2.0774918075346847	[290]	[15]	-8	hSpCas9	negative selection	480805
64807978	64808001	11	+	26472758	Raji	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	-1.432349711354559	[313]	[26]	-7	hSpCas9	negative selection	480806
64807042	64807065	11	-	26472758	Raji	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-2.643044318599169	[322]	[11]	-9	hSpCas9	negative selection	480807
64805667	64805690	11	-	26472758	Raji	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	-1.8926164646264008	[31]	[1]	-8	hSpCas9	negative selection	480808
64805157	64805180	11	+	26472758	Raji	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	-1.6999713866840045	[125]	[8]	-8	hSpCas9	negative selection	480809
64809935	64809958	11	+	26472758	Raji	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-0.7434730253205913	[201]	[27]	-5	hSpCas9	negative selection	480810
64809877	64809900	11	+	26472758	Raji	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	-0.3204780042628279	[338]	[62]	-3	hSpCas9	negative selection	480811
64809828	64809851	11	+	26472758	Raji	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-2.0625414660687134	[35]	[1]	-8	hSpCas9	negative selection	480812
64809852	64809875	11	+	26472758	K562	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	-2.0598555026570406	[730]	[147]	-7	hSpCas9	negative selection	671921
64809699	64809722	11	-	26472758	K562	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-3.0054058209497363	[760]	[79]	-8	hSpCas9	negative selection	671922
64808050	64808073	11	+	26472758	K562	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	-1.3599090979216404	[449]	[147]	-6	hSpCas9	negative selection	671923
64807978	64808001	11	+	26472758	K562	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	-2.8499086548817063	[631]	[73]	-8	hSpCas9	negative selection	671924
64807042	64807065	11	-	26472758	K562	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-5.016108822556772	[344]	[8]	-9	hSpCas9	negative selection	671925
64805667	64805690	11	-	26472758	K562	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	-0.723872412606215	[44]	[22]	-4	hSpCas9	negative selection	671926
64805157	64805180	11	+	26472758	K562	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	0.8147344524232016	[65]	[97]	6	hSpCas9	negative selection	671927
64809935	64809958	11	+	26472758	K562	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-8.435061371838998	[409]	[0]	-9	hSpCas9	negative selection	671928
64809877	64809900	11	+	26472758	K562	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	-2.1662135924923955	[435]	[81]	-7	hSpCas9	negative selection	671929
64809828	64809851	11	+	26472758	K562	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	0.5800217594508856	[41]	[52]	5	hSpCas9	negative selection	671930
64805745	64805768	11	-	26627737	DLD1	viability	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-3.5243312710488928	[706]	[13,7,32]	-9	hSpCas9	negative selection	779968
64806278	64806301	11	+	26627737	DLD1	viability	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-3.2635168178112917	[1454]	[42,26,67]	-9	hSpCas9	negative selection	779969
64807025	64807048	11	+	26627737	DLD1	viability	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-2.9138140437468953	[587]	[21,1,44]	-9	hSpCas9	negative selection	779970
64807632	64807655	11	-	26627737	DLD1	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-2.414987838101308	[603]	[35,56,16]	-9	hSpCas9	negative selection	779971
64807890	64807913	11	-	26627737	DLD1	viability	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.31395240891560966	[353]	[184,154,81]	3	hSpCas9	negative selection	779972
64809782	64809805	11	+	26627737	DLD1	viability	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-2.8215404162676454	[566]	[46,0,25]	-9	hSpCas9	negative selection	779973
64805745	64805768	11	-	26627737	GBM cells	viability after 5 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	0.03384345497179403	[305]	[180,154]	0	hSpCas9	negative selection	862283
64806278	64806301	11	+	26627737	GBM cells	viability after 5 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-0.28311008730013754	[463]	[203,204]	-4	hSpCas9	negative selection	862284
64807025	64807048	11	+	26627737	GBM cells	viability after 5 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-0.8060793295422407	[237]	[73,71]	-8	hSpCas9	negative selection	862285
64807632	64807655	11	-	26627737	GBM cells	viability after 5 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.079226691150575	[261]	[124,140]	-1	hSpCas9	negative selection	862286
64807890	64807913	11	-	26627737	GBM cells	viability after 5 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.04000619412028528	[145]	[61,98]	0	hSpCas9	negative selection	862287
64809782	64809805	11	+	26627737	GBM cells	viability after 5 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.46430242849230874	[318]	[149,97]	-6	hSpCas9	negative selection	862288
64805745	64805768	11	-	26627737	GBM cells	viability after 13 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-0.29736944701843654	[305]	[133,135]	-4	hSpCas9	negative selection	944598
64806278	64806301	11	+	26627737	GBM cells	viability after 13 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	0.11376732890422925	[463]	[267,275]	1	hSpCas9	negative selection	944599
64807025	64807048	11	+	26627737	GBM cells	viability after 13 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-0.60033159389663	[237]	[93,77]	-6	hSpCas9	negative selection	944600
64807632	64807655	11	-	26627737	GBM cells	viability after 13 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.10384757946906524	[261]	[165,141]	1	hSpCas9	negative selection	944601
64807890	64807913	11	-	26627737	GBM cells	viability after 13 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.20298456529282194	[145]	[115,70]	2	hSpCas9	negative selection	944602
64809782	64809805	11	+	26627737	GBM cells	viability after 13 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.26435351883792907	[318]	[217,83]	-3	hSpCas9	negative selection	944603
64805745	64805768	11	-	26627737	GBM cells	viability after 21 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	0.2873915054649162	[305]	[228,178]	3	hSpCas9	negative selection	1026913
64806278	64806301	11	+	26627737	GBM cells	viability after 21 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	0.5534171278629315	[463]	[382,357]	5	hSpCas9	negative selection	1026914
64807025	64807048	11	+	26627737	GBM cells	viability after 21 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-1.430958410533943	[237]	[48,46]	-8	hSpCas9	negative selection	1026915
64807632	64807655	11	-	26627737	GBM cells	viability after 21 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.25836836298708377	[261]	[175,164]	2	hSpCas9	negative selection	1026916
64807890	64807913	11	-	26627737	GBM cells	viability after 21 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.6780833136623137	[145]	[128,124]	6	hSpCas9	negative selection	1026917
64809782	64809805	11	+	26627737	GBM cells	viability after 21 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	0.48035852565881587	[318]	[246,236]	5	hSpCas9	negative selection	1026918
64805745	64805768	11	-	26627737	RPE1	viability after 9 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	0.6578733891915056	[583]	[363,190]	4	hSpCas9	negative selection	1109228
64806278	64806301	11	+	26627737	RPE1	viability after 9 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-1.7557629769332492	[1626]	[128,178]	-8	hSpCas9	negative selection	1109229
64807025	64807048	11	+	26627737	RPE1	viability after 9 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-1.4793037476775472	[1010]	[154,59]	-8	hSpCas9	negative selection	1109230
64807632	64807655	11	-	26627737	RPE1	viability after 9 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.28598966195001835	[822]	[216,203]	-2	hSpCas9	negative selection	1109231
64807890	64807913	11	-	26627737	RPE1	viability after 9 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	-0.8619522006736271	[1147]	[195,199]	-6	hSpCas9	negative selection	1109232
64809782	64809805	11	+	26627737	RPE1	viability after 9 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-1.3704870917755665	[897]	[130,79]	-7	hSpCas9	negative selection	1109233
64805745	64805768	11	-	26627737	RPE1	viability after 12 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-0.0512195198139222	[583]	[165,135]	0	hSpCas9	negative selection	1191543
64806278	64806301	11	+	26627737	RPE1	viability after 12 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-1.9203165345646211	[1626]	[114,115]	-8	hSpCas9	negative selection	1191544
64807025	64807048	11	+	26627737	RPE1	viability after 12 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-2.2649121764157325	[1010]	[73,37]	-8	hSpCas9	negative selection	1191545
64807632	64807655	11	-	26627737	RPE1	viability after 12 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.5101213754714796	[822]	[146,163]	-4	hSpCas9	negative selection	1191546
64807890	64807913	11	-	26627737	RPE1	viability after 12 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	-1.9309824980417694	[1147]	[93,66]	-8	hSpCas9	negative selection	1191547
64809782	64809805	11	+	26627737	RPE1	viability after 12 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-1.6812514339669127	[897]	[99,48]	-8	hSpCas9	negative selection	1191548
64805745	64805768	11	-	26627737	RPE1	viability after 15 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	0.0939499764246387	[583]	[270,84]	0	hSpCas9	negative selection	1273858
64806278	64806301	11	+	26627737	RPE1	viability after 15 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-1.499926467492279	[1626]	[177,147]	-7	hSpCas9	negative selection	1273859
64807025	64807048	11	+	26627737	RPE1	viability after 15 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-2.7631555149763956	[1010]	[34,48]	-9	hSpCas9	negative selection	1273860
64807632	64807655	11	-	26627737	RPE1	viability after 15 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.4760156241579726	[822]	[145,187]	-3	hSpCas9	negative selection	1273861
64807890	64807913	11	-	26627737	RPE1	viability after 15 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	-2.1740492862012957	[1147]	[17,123]	-8	hSpCas9	negative selection	1273862
64809782	64809805	11	+	26627737	RPE1	viability after 15 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-1.9408229516326643	[897]	[84,47]	-8	hSpCas9	negative selection	1273863
64805745	64805768	11	-	26627737	RPE1	viability after 18 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-0.16133251462470227	[583]	[167,111]	-1	hSpCas9	negative selection	1356173
64806278	64806301	11	+	26627737	RPE1	viability after 18 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-2.679849089123966	[1626]	[39,98]	-9	hSpCas9	negative selection	1356174
64807025	64807048	11	+	26627737	RPE1	viability after 18 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-3.587489490273456	[1010]	[42,0]	-9	hSpCas9	negative selection	1356175
64807632	64807655	11	-	26627737	RPE1	viability after 18 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-1.412481942277575	[822]	[66,100]	-7	hSpCas9	negative selection	1356176
64807890	64807913	11	-	26627737	RPE1	viability after 18 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	-1.513655925639263	[1147]	[93,123]	-7	hSpCas9	negative selection	1356177
64809782	64809805	11	+	26627737	RPE1	viability after 18 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-2.229168123228316	[897]	[27,76]	-8	hSpCas9	negative selection	1356178
64805745	64805768	11	-	26627737	HeLa	viability after 8 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	0.2987747205622678	[415]	[78,254,296]	3	hSpCas9	negative selection	1438488
64806278	64806301	11	+	26627737	HeLa	viability after 8 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-0.8839671517410668	[1122]	[467,178,196]	-7	hSpCas9	negative selection	1438489
64807025	64807048	11	+	26627737	HeLa	viability after 8 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	0.716705273672489	[272]	[266,235,104]	6	hSpCas9	negative selection	1438490
64807632	64807655	11	-	26627737	HeLa	viability after 8 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	1.3498701407852278	[306]	[280,469,262]	8	hSpCas9	negative selection	1438491
64807890	64807913	11	-	26627737	HeLa	viability after 8 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.5480325309886446	[245]	[141,162,160]	5	hSpCas9	negative selection	1438492
64809782	64809805	11	+	26627737	HeLa	viability after 8 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.4127767395493625	[668]	[284,231,157]	-4	hSpCas9	negative selection	1438493
64805745	64805768	11	-	26627737	HeLa	viability after 12 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-0.11142751532233043	[415]	[150,141,185]	-1	hSpCas9	negative selection	1520803
64806278	64806301	11	+	26627737	HeLa	viability after 12 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-1.1272258526573116	[1122]	[102,270,253]	-8	hSpCas9	negative selection	1520804
64807025	64807048	11	+	26627737	HeLa	viability after 12 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	1.0297817526991855	[272]	[228,220,241]	7	hSpCas9	negative selection	1520805
64807632	64807655	11	-	26627737	HeLa	viability after 12 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.5019743643487647	[306]	[197,80,270]	4	hSpCas9	negative selection	1520806
64807890	64807913	11	-	26627737	HeLa	viability after 12 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.2415484509812612	[245]	[110,141,104]	2	hSpCas9	negative selection	1520807
64809782	64809805	11	+	26627737	HeLa	viability after 12 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.5191634256301509	[668]	[298,96,195]	-4	hSpCas9	negative selection	1520808
64805745	64805768	11	-	26627737	HeLa	viability after 15 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-1.0825881142808484	[415]	[28,89,124]	-7	hSpCas9	negative selection	1603118
64806278	64806301	11	+	26627737	HeLa	viability after 15 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-1.1405982025751764	[1122]	[123,172,335]	-7	hSpCas9	negative selection	1603119
64807025	64807048	11	+	26627737	HeLa	viability after 15 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	0.03994239711241393	[272]	[53,181,106]	0	hSpCas9	negative selection	1603120
64807632	64807655	11	-	26627737	HeLa	viability after 15 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	1.3888013833331232	[306]	[438,254,282]	8	hSpCas9	negative selection	1603121
64807890	64807913	11	-	26627737	HeLa	viability after 15 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.2412280981031415	[245]	[2,145,214]	2	hSpCas9	negative selection	1603122
64809782	64809805	11	+	26627737	HeLa	viability after 15 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.7628698874121588	[668]	[212,56,214]	-6	hSpCas9	negative selection	1603123
64805745	64805768	11	-	26627737	HeLa	viability after 18 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-1.115192777406727	[415]	[17,71,124]	-7	hSpCas9	negative selection	1685433
64806278	64806301	11	+	26627737	HeLa	viability after 18 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-1.131323924833712	[1122]	[85,142,335]	-7	hSpCas9	negative selection	1685434
64807025	64807048	11	+	26627737	HeLa	viability after 18 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-0.037343005524185124	[272]	[33,138,106]	0	hSpCas9	negative selection	1685435
64807632	64807655	11	-	26627737	HeLa	viability after 18 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	1.3694727692063948	[306]	[294,199,282]	8	hSpCas9	negative selection	1685436
64807890	64807913	11	-	26627737	HeLa	viability after 18 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.24669214287570657	[245]	[1,121,214]	2	hSpCas9	negative selection	1685437
64809782	64809805	11	+	26627737	HeLa	viability after 18 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.7357428518954996	[668]	[148,46,214]	-6	hSpCas9	negative selection	1685438
64805745	64805768	11	-	26627737	HCT116	viability after 6 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-0.6479747549128235	[959]	[221,26]	-4	hSpCas9	negative selection	1767748
64806278	64806301	11	+	26627737	HCT116	viability after 6 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	1.6581103460400681	[883]	[727,278]	8	hSpCas9	negative selection	1767749
64807025	64807048	11	+	26627737	HCT116	viability after 6 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	1.0881250524233175	[718]	[423,138]	6	hSpCas9	negative selection	1767750
64807632	64807655	11	-	26627737	HCT116	viability after 6 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.3776588416639786	[579]	[55,77]	-2	hSpCas9	negative selection	1767751
64807890	64807913	11	-	26627737	HCT116	viability after 6 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	1.3652301121574717	[376]	[55,205]	7	hSpCas9	negative selection	1767752
64809782	64809805	11	+	26627737	HCT116	viability after 6 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.20955906351437426	[891]	[99,132]	-1	hSpCas9	negative selection	1767753
64805745	64805768	11	-	26627737	HCT116	viability after 8 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-0.36603495112939743	[407]	[179,216,126]	-4	hSpCas9	negative selection	1850063
64806278	64806301	11	+	26627737	HCT116	viability after 8 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-0.49679812361944664	[487]	[226,208,136]	-5	hSpCas9	negative selection	1850064
64807025	64807048	11	+	26627737	HCT116	viability after 8 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	0.7304505869142734	[196]	[160,200,177]	7	hSpCas9	negative selection	1850065
64807632	64807655	11	-	26627737	HCT116	viability after 8 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-1.1092838987548659	[590]	[121,151,177]	-8	hSpCas9	negative selection	1850066
64807890	64807913	11	-	26627737	HCT116	viability after 8 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	2.348167259276885	[41]	[90,140,120]	9	hSpCas9	negative selection	1850067
64809782	64809805	11	+	26627737	HCT116	viability after 8 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	0.19156328960026908	[352]	[187,272,204]	2	hSpCas9	negative selection	1850068
64805745	64805768	11	-	26627737	HCT116	viability after 9 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-0.528725259099484	[959]	[256,114]	-4	hSpCas9	negative selection	1932378
64806278	64806301	11	+	26627737	HCT116	viability after 9 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	0.21203274560250118	[883]	[340,219]	1	hSpCas9	negative selection	1932379
64807025	64807048	11	+	26627737	HCT116	viability after 9 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	1.0517664714578194	[718]	[335,446]	7	hSpCas9	negative selection	1932380
64807632	64807655	11	-	26627737	HCT116	viability after 9 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.10582451965600267	[579]	[188,148]	0	hSpCas9	negative selection	1932381
64807890	64807913	11	-	26627737	HCT116	viability after 9 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	1.1351184345518406	[376]	[305,153]	7	hSpCas9	negative selection	1932382
64809782	64809805	11	+	26627737	HCT116	viability after 9 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.41165871497049983	[891]	[106,235]	-3	hSpCas9	negative selection	1932383
64805745	64805768	11	-	26627737	HCT116	viability after 12 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-0.02466343400667681	[407]	[212,245,173]	0	hSpCas9	negative selection	2014693
64806278	64806301	11	+	26627737	HCT116	viability after 12 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-0.40679398682550044	[487]	[214,133,227]	-4	hSpCas9	negative selection	2014694
64807025	64807048	11	+	26627737	HCT116	viability after 12 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	0.5624008801659046	[196]	[146,145,165]	5	hSpCas9	negative selection	2014695
64807632	64807655	11	-	26627737	HCT116	viability after 12 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-1.2602440268925947	[590]	[153,135,96]	-8	hSpCas9	negative selection	2014696
64807890	64807913	11	-	26627737	HCT116	viability after 12 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	2.762235301452577	[41]	[99,206,147]	9	hSpCas9	negative selection	2014697
64809782	64809805	11	+	26627737	HCT116	viability after 12 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.01223148706011945	[352]	[181,224,145]	0	hSpCas9	negative selection	2014698
64805745	64805768	11	-	26627737	HCT116	viability after 15 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-0.5135369716668898	[407]	[226,186,86]	-5	hSpCas9	negative selection	2097008
64806278	64806301	11	+	26627737	HCT116	viability after 15 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-0.5315637800437506	[487]	[197,177,205]	-5	hSpCas9	negative selection	2097009
64807025	64807048	11	+	26627737	HCT116	viability after 15 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	0.9074776436964918	[196]	[178,273,179]	7	hSpCas9	negative selection	2097010
64807632	64807655	11	-	26627737	HCT116	viability after 15 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-1.2531616718239875	[590]	[222,72,140]	-8	hSpCas9	negative selection	2097011
64807890	64807913	11	-	26627737	HCT116	viability after 15 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	2.203412167177976	[41]	[85,114,128]	9	hSpCas9	negative selection	2097012
64809782	64809805	11	+	26627737	HCT116	viability after 15 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	0.14366642947706593	[352]	[125,231,300]	1	hSpCas9	negative selection	2097013
64805745	64805768	11	-	26627737	HCT116	viability after 18 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	0.3950768799643767	[407]	[321,371,67]	3	hSpCas9	negative selection	2179323
64806278	64806301	11	+	26627737	HCT116	viability after 18 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-0.19263410611034404	[487]	[191,214,211]	-2	hSpCas9	negative selection	2179324
64807025	64807048	11	+	26627737	HCT116	viability after 18 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	0.9392075574501754	[196]	[132,158,260]	7	hSpCas9	negative selection	2179325
64807632	64807655	11	-	26627737	HCT116	viability after 18 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-1.6798034735347835	[590]	[78,97,89]	-8	hSpCas9	negative selection	2179326
64807890	64807913	11	-	26627737	HCT116	viability after 18 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	3.1848006381648974	[41]	[222,210,114]	9	hSpCas9	negative selection	2179327
64809782	64809805	11	+	26627737	HCT116	viability after 18 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.4215239615423473	[352]	[91,186,97]	-4	hSpCas9	negative selection	2179328
64809975	64809998	11	+	24336569	HL60	viability	CTCCACGAAGCCCAGCACCAAGG	MEN1	ENSG00000133895	0.33815717019004277	[981]	[2626]	3	hSpCas9	negative selection	2277181
64809985	64810008	11	-	24336569	HL60	viability	GTGCTCCTTTCCTTGGTGCTGGG	MEN1	ENSG00000133895	-0.3630039753147633	[611]	[1006]	-3	hSpCas9	negative selection	2277182
64809992	64810015	11	-	24336569	HL60	viability	GGACCTGGTGCTCCTTTCCTTGG	MEN1	ENSG00000133895	0.35149530664720985	[639]	[1727]	3	hSpCas9	negative selection	2277183
64810004	64810027	11	+	24336569	HL60	viability	GCACCAGGTCCGGCTCCTCTCGG	MEN1	ENSG00000133895	0.2595728172061706	[404]	[1025]	2	hSpCas9	negative selection	2277184
64810013	64810036	11	-	24336569	HL60	viability	CGAGCTGGGCCGAGAGGAGCCGG	MEN1	ENSG00000133895	0.2829473255799795	[86]	[223]	2	hSpCas9	negative selection	2277185
64810019	64810042	11	-	24336569	HL60	viability	TGCTGCCGAGCTGGGCCGAGAGG	MEN1	ENSG00000133895	-0.4100868480902671	[971]	[1547]	-4	hSpCas9	negative selection	2277186
64810025	64810048	11	+	24336569	HL60	viability	GGCCCAGCTCGGCAGCAAACAGG	MEN1	ENSG00000133895	0.34671420851541024	[805]	[2168]	3	hSpCas9	negative selection	2277187
64810044	64810067	11	+	24336569	HL60	viability	CAGGCGCACCACGTCGTCGATGG	MEN1	ENSG00000133895	0.19703156839691793	[1105]	[2682]	2	hSpCas9	negative selection	2277188
64810052	64810075	11	-	24336569	HL60	viability	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	0.34472625958867364	[450]	[1211]	3	hSpCas9	negative selection	2277189
64810070	64810093	11	+	24336569	HL60	viability	GCAGCGGGAACAGCGTCTTCTGG	MEN1	ENSG00000133895	-0.1583328640131669	[423]	[803]	-1	hSpCas9	negative selection	2277190
64809975	64809998	11	+	24336569	KBM7	viability	CTCCACGAAGCCCAGCACCAAGG	MEN1	ENSG00000133895	-2.282036262661662	[805]	[451]	-8	hSpCas9	negative selection	2344358
64809985	64810008	11	-	24336569	KBM7	viability	GTGCTCCTTTCCTTGGTGCTGGG	MEN1	ENSG00000133895	-2.7015416968862005	[538]	[225]	-9	hSpCas9	negative selection	2344359
64809992	64810015	11	-	24336569	KBM7	viability	GGACCTGGTGCTCCTTTCCTTGG	MEN1	ENSG00000133895	-0.5855016821257457	[860]	[1564]	-5	hSpCas9	negative selection	2344360
64810004	64810027	11	+	24336569	KBM7	viability	GCACCAGGTCCGGCTCCTCTCGG	MEN1	ENSG00000133895	-1.4603653515047257	[339]	[336]	-7	hSpCas9	negative selection	2344361
64810013	64810036	11	-	24336569	KBM7	viability	CGAGCTGGGCCGAGAGGAGCCGG	MEN1	ENSG00000133895	-0.9791922726771047	[72]	[100]	-6	hSpCas9	negative selection	2344362
64810019	64810042	11	-	24336569	KBM7	viability	TGCTGCCGAGCTGGGCCGAGAGG	MEN1	ENSG00000133895	-2.0093093910323216	[461]	[312]	-8	hSpCas9	negative selection	2344363
64810025	64810048	11	+	24336569	KBM7	viability	GGCCCAGCTCGGCAGCAAACAGG	MEN1	ENSG00000133895	1.0451034466241587	[424]	[2391]	8	hSpCas9	negative selection	2344364
64810044	64810067	11	+	24336569	KBM7	viability	CAGGCGCACCACGTCGTCGATGG	MEN1	ENSG00000133895	-1.4757362090368404	[1189]	[1166]	-7	hSpCas9	negative selection	2344365
64810052	64810075	11	-	24336569	KBM7	viability	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	-1.8526029071997072	[334]	[252]	-8	hSpCas9	negative selection	2344366
64810070	64810093	11	+	24336569	KBM7	viability	GCAGCGGGAACAGCGTCTTCTGG	MEN1	ENSG00000133895	0.8818727487202922	[152]	[768]	7	hSpCas9	negative selection	2344367
64810880	64810903	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGTTATGAGGAAAAAGATCAGG	MEN1	ENSG00000133895	1.2301306725279506	[344,133]	[204,33]	5	dCas9-VP64	positive selection	2383515
64810852	64810875	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCGACCCGTGACAGCAAAACCGG	MEN1	ENSG00000133895	0.07889612004355118	[279,226]	[95,17]	0	dCas9-VP64	positive selection	2383516
64810806	64810829	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGGCACTACCTGCAGACTCGG	MEN1	ENSG00000133895	1.221434732315343	[1140,321]	[115,648]	5	dCas9-VP64	positive selection	2383517
64810645	64810668	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCGGCCCGCCACTATTTCCAGG	MEN1	ENSG00000133895	-1.8523008308830815	[556,549]	[23,42]	-8	dCas9-VP64	positive selection	2463189
64810700	64810723	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAAGGAGGTGTCCGGAGCCGCGG	MEN1	ENSG00000133895	1.6187891275926107	[615,693]	[795,62]	6	dCas9-VP64	positive selection	2463190
64810722	64810745	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCCAATCCCTGAGTATCTCGGG	MEN1	ENSG00000133895	-0.2596500817894978	[237,230]	[38,46]	-1	dCas9-VP64	positive selection	2463191
64810880	64810903	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGTTATGAGGAAAAAGATCAGG	MEN1	ENSG00000133895	-0.9716276226538226	[282,154]	[44,27]	-8	dCas9-VP64	positive selection	2478770
64810852	64810875	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCGACCCGTGACAGCAAAACCGG	MEN1	ENSG00000133895	0.6666452013328947	[204,233]	[71,151]	5	dCas9-VP64	positive selection	2478771
64810806	64810829	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGGCACTACCTGCAGACTCGG	MEN1	ENSG00000133895	-0.19902066220920522	[156,436]	[65,99]	-2	dCas9-VP64	positive selection	2478772
64810645	64810668	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCGGCCCGCCACTATTTCCAGG	MEN1	ENSG00000133895	-0.28972670771728326	[214,292]	[67,66]	-3	dCas9-VP64	positive selection	2558444
64810700	64810723	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAAGGAGGTGTCCGGAGCCGCGG	MEN1	ENSG00000133895	0.8832730614917264	[67,91]	[28,65]	6	dCas9-VP64	positive selection	2558445
64810722	64810745	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCCAATCCCTGAGTATCTCGGG	MEN1	ENSG00000133895	0.946740300790903	[200,281]	[238,69]	6	dCas9-VP64	positive selection	2558446
64809749	64809772	11	-	27260157	DLD1	viability	CAGCCGTGAGCTGGTGAAGAAGG	MEN1	ENSG00000133895	-1.94658372666728	[]	[]	-8	hSpCas9	negative selection	2580057
64809985	64810008	11	-	27260157	DLD1	viability	GTGCTCCTTTCCTTGGTGCTGGG	MEN1	ENSG00000133895	-2.20670325351616	[]	[]	-9	hSpCas9	negative selection	2583791
64810044	64810067	11	+	27260157	DLD1	viability	CAGGCGCACCACGTCGTCGATGG	MEN1	ENSG00000133895	-2.3893615089161	[]	[]	-9	hSpCas9	negative selection	2584928
64809782	64809805	11	+	27260157	DLD1	viability	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-1.18103288766773	[]	[]	-7	hSpCas9	negative selection	2585106
64809925	64809948	11	+	27260157	DLD1	viability	GTGAGCTCGGGAACGTTGGTAGG	MEN1	ENSG00000133895	-2.19129909897988	[]	[]	-9	hSpCas9	negative selection	2604499
64809992	64810015	11	-	27260157	DLD1	viability	GGACCTGGTGCTCCTTTCCTTGG	MEN1	ENSG00000133895	-1.64678705399662	[]	[]	-8	hSpCas9	negative selection	2605091
64810054	64810077	11	+	27260157	DLD1	viability	ACGTCGTCGATGGAGCGCAGCGG	MEN1	ENSG00000133895	-2.62823862615931	[]	[]	-9	hSpCas9	negative selection	2606230
64809866	64809889	11	+	27260157	DLD1	viability	CGGCCACGGGAAAGTAGGTGAGG	MEN1	ENSG00000133895	-3.99071903909354	[]	[]	-9	hSpCas9	negative selection	2609872
64809842	64809865	11	+	27260157	DLD1	viability	AGAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-2.01122928541786	[]	[]	-8	hSpCas9	negative selection	2612039
64809975	64809998	11	+	27260157	DLD1	viability	CTCCACGAAGCCCAGCACCAAGG	MEN1	ENSG00000133895	-2.05059370367776	[]	[]	-8	hSpCas9	negative selection	2612342
64810019	64810042	11	-	27260157	DLD1	viability	TGCTGCCGAGCTGGGCCGAGAGG	MEN1	ENSG00000133895	-1.90598739986032	[]	[]	-8	hSpCas9	negative selection	2613130
64809797	64809820	11	+	27260157	DLD1	viability	GGGACAGGTCGACGGCGCCTCGG	MEN1	ENSG00000133895	-0.795403795580238	[]	[]	-6	hSpCas9	negative selection	2613661
64810013	64810036	11	-	27260157	DLD1	viability	CGAGCTGGGCCGAGAGGAGCCGG	MEN1	ENSG00000133895	-2.32203454627338	[]	[]	-9	hSpCas9	negative selection	2616033
64810025	64810048	11	+	27260157	DLD1	viability	GGCCCAGCTCGGCAGCAAACAGG	MEN1	ENSG00000133895	-2.12722020468027	[]	[]	-9	hSpCas9	negative selection	2617518
64810027	64810050	11	-	27260157	DLD1	viability	CGCCTGTTTGCTGCCGAGCTGGG	MEN1	ENSG00000133895	0.219188905792035	[]	[]	3	hSpCas9	negative selection	2619879
64810004	64810027	11	+	27260157	DLD1	viability	GCACCAGGTCCGGCTCCTCTCGG	MEN1	ENSG00000133895	-2.76114953934862	[]	[]	-9	hSpCas9	negative selection	2622060
64810052	64810075	11	-	27260157	DLD1	viability	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	-1.10131828415848	[]	[]	-7	hSpCas9	negative selection	2644237
64809807	64809830	11	+	27260157	DLD1	viability	GACGGCGCCTCGGATCTGGGCGG	MEN1	ENSG00000133895	-2.44708739179646	[]	[]	-9	hSpCas9	negative selection	2646169
64809778	64809801	11	-	27260157	DLD1	viability	TCCCTCTATCCTCGAGAAGGGGG	MEN1	ENSG00000133895	-2.41259076755871	[]	[]	-9	hSpCas9	negative selection	2647181
64809749	64809772	11	-	27260157	HT1080	viability	CAGCCGTGAGCTGGTGAAGAAGG	MEN1	ENSG00000133895	0.425664481401888	[]	[]	4	hSpCas9	negative selection	2656187
64809985	64810008	11	-	27260157	HT1080	viability	GTGCTCCTTTCCTTGGTGCTGGG	MEN1	ENSG00000133895	0.678020792627523	[]	[]	6	hSpCas9	negative selection	2659921
64810044	64810067	11	+	27260157	HT1080	viability	CAGGCGCACCACGTCGTCGATGG	MEN1	ENSG00000133895	0.70437408633025	[]	[]	6	hSpCas9	negative selection	2661058
64809782	64809805	11	+	27260157	HT1080	viability	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	0.813096231679623	[]	[]	7	hSpCas9	negative selection	2661236
64809925	64809948	11	+	27260157	HT1080	viability	GTGAGCTCGGGAACGTTGGTAGG	MEN1	ENSG00000133895	-0.240925519393853	[]	[]	0	hSpCas9	negative selection	2680629
64809992	64810015	11	-	27260157	HT1080	viability	GGACCTGGTGCTCCTTTCCTTGG	MEN1	ENSG00000133895	1.11190744842642	[]	[]	8	hSpCas9	negative selection	2681221
64810054	64810077	11	+	27260157	HT1080	viability	ACGTCGTCGATGGAGCGCAGCGG	MEN1	ENSG00000133895	1.09867580386195	[]	[]	8	hSpCas9	negative selection	2682360
64809866	64809889	11	+	27260157	HT1080	viability	CGGCCACGGGAAAGTAGGTGAGG	MEN1	ENSG00000133895	-0.206543057797765	[]	[]	0	hSpCas9	negative selection	2686002
64809842	64809865	11	+	27260157	HT1080	viability	AGAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-0.905283767710114	[]	[]	-8	hSpCas9	negative selection	2688169
64809975	64809998	11	+	27260157	HT1080	viability	CTCCACGAAGCCCAGCACCAAGG	MEN1	ENSG00000133895	1.29589000032391	[]	[]	9	hSpCas9	negative selection	2688472
64810019	64810042	11	-	27260157	HT1080	viability	TGCTGCCGAGCTGGGCCGAGAGG	MEN1	ENSG00000133895	0.371884708012799	[]	[]	3	hSpCas9	negative selection	2689260
64809797	64809820	11	+	27260157	HT1080	viability	GGGACAGGTCGACGGCGCCTCGG	MEN1	ENSG00000133895	-0.181967508411931	[]	[]	0	hSpCas9	negative selection	2689791
64810013	64810036	11	-	27260157	HT1080	viability	CGAGCTGGGCCGAGAGGAGCCGG	MEN1	ENSG00000133895	-0.528523366445769	[]	[]	-7	hSpCas9	negative selection	2692163
64810025	64810048	11	+	27260157	HT1080	viability	GGCCCAGCTCGGCAGCAAACAGG	MEN1	ENSG00000133895	0.740456854377886	[]	[]	6	hSpCas9	negative selection	2693648
64810027	64810050	11	-	27260157	HT1080	viability	CGCCTGTTTGCTGCCGAGCTGGG	MEN1	ENSG00000133895	0.744845831791528	[]	[]	6	hSpCas9	negative selection	2696009
64810004	64810027	11	+	27260157	HT1080	viability	GCACCAGGTCCGGCTCCTCTCGG	MEN1	ENSG00000133895	0.0821160170781906	[]	[]	0	hSpCas9	negative selection	2698190
64810052	64810075	11	-	27260157	HT1080	viability	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	1.20649389868229	[]	[]	8	hSpCas9	negative selection	2720367
64809807	64809830	11	+	27260157	HT1080	viability	GACGGCGCCTCGGATCTGGGCGG	MEN1	ENSG00000133895	0.65711918425495	[]	[]	6	hSpCas9	negative selection	2722299
64809778	64809801	11	-	27260157	HT1080	viability	TCCCTCTATCCTCGAGAAGGGGG	MEN1	ENSG00000133895	-0.905970436758041	[]	[]	-8	hSpCas9	negative selection	2723311
64809749	64809772	11	-	27260157	MKN45	viability	CAGCCGTGAGCTGGTGAAGAAGG	MEN1	ENSG00000133895	0.820803879156363	[]	[]	8	hSpCas9	negative selection	2732317
64809985	64810008	11	-	27260157	MKN45	viability	GTGCTCCTTTCCTTGGTGCTGGG	MEN1	ENSG00000133895	-0.988967827620734	[]	[]	-7	hSpCas9	negative selection	2736051
64810044	64810067	11	+	27260157	MKN45	viability	CAGGCGCACCACGTCGTCGATGG	MEN1	ENSG00000133895	-0.376114406177836	[]	[]	-1	hSpCas9	negative selection	2737188
64809782	64809805	11	+	27260157	MKN45	viability	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.102967488960432	[]	[]	0	hSpCas9	negative selection	2737366
64809925	64809948	11	+	27260157	MKN45	viability	GTGAGCTCGGGAACGTTGGTAGG	MEN1	ENSG00000133895	-1.01004720396324	[]	[]	-8	hSpCas9	negative selection	2756759
64809992	64810015	11	-	27260157	MKN45	viability	GGACCTGGTGCTCCTTTCCTTGG	MEN1	ENSG00000133895	-0.235609074689874	[]	[]	-1	hSpCas9	negative selection	2757351
64810054	64810077	11	+	27260157	MKN45	viability	ACGTCGTCGATGGAGCGCAGCGG	MEN1	ENSG00000133895	0.287867465931238	[]	[]	5	hSpCas9	negative selection	2758490
64809866	64809889	11	+	27260157	MKN45	viability	CGGCCACGGGAAAGTAGGTGAGG	MEN1	ENSG00000133895	-1.17851138676107	[]	[]	-8	hSpCas9	negative selection	2762132
64809842	64809865	11	+	27260157	MKN45	viability	AGAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-1.04651699090779	[]	[]	-8	hSpCas9	negative selection	2764299
64809975	64809998	11	+	27260157	MKN45	viability	CTCCACGAAGCCCAGCACCAAGG	MEN1	ENSG00000133895	-1.22895220042569	[]	[]	-8	hSpCas9	negative selection	2764602
64810019	64810042	11	-	27260157	MKN45	viability	TGCTGCCGAGCTGGGCCGAGAGG	MEN1	ENSG00000133895	-1.26135450044731	[]	[]	-8	hSpCas9	negative selection	2765390
64809797	64809820	11	+	27260157	MKN45	viability	GGGACAGGTCGACGGCGCCTCGG	MEN1	ENSG00000133895	0.209918084191312	[]	[]	5	hSpCas9	negative selection	2765921
64810013	64810036	11	-	27260157	MKN45	viability	CGAGCTGGGCCGAGAGGAGCCGG	MEN1	ENSG00000133895	-2.10298127429769	[]	[]	-9	hSpCas9	negative selection	2768293
64810025	64810048	11	+	27260157	MKN45	viability	GGCCCAGCTCGGCAGCAAACAGG	MEN1	ENSG00000133895	-0.666906292538612	[]	[]	-7	hSpCas9	negative selection	2769778
64810027	64810050	11	-	27260157	MKN45	viability	CGCCTGTTTGCTGCCGAGCTGGG	MEN1	ENSG00000133895	1.16010433442456	[]	[]	8	hSpCas9	negative selection	2772139
64810004	64810027	11	+	27260157	MKN45	viability	GCACCAGGTCCGGCTCCTCTCGG	MEN1	ENSG00000133895	-1.39747481621937	[]	[]	-8	hSpCas9	negative selection	2774320
64810052	64810075	11	-	27260157	MKN45	viability	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	0.831871708165823	[]	[]	8	hSpCas9	negative selection	2796497
64809807	64809830	11	+	27260157	MKN45	viability	GACGGCGCCTCGGATCTGGGCGG	MEN1	ENSG00000133895	-0.455587457836854	[]	[]	-6	hSpCas9	negative selection	2798429
64809778	64809801	11	-	27260157	MKN45	viability	TCCCTCTATCCTCGAGAAGGGGG	MEN1	ENSG00000133895	-2.18865635858075	[]	[]	-9	hSpCas9	negative selection	2799441
64809749	64809772	11	-	27260157	RKO	viability	CAGCCGTGAGCTGGTGAAGAAGG	MEN1	ENSG00000133895	-0.793876580853618	[]	[]	-7	hSpCas9	negative selection	2808447
64809985	64810008	11	-	27260157	RKO	viability	GTGCTCCTTTCCTTGGTGCTGGG	MEN1	ENSG00000133895	-0.810337758875185	[]	[]	-7	hSpCas9	negative selection	2812181
64810044	64810067	11	+	27260157	RKO	viability	CAGGCGCACCACGTCGTCGATGG	MEN1	ENSG00000133895	0.51549595882282	[]	[]	2	hSpCas9	negative selection	2813318
64809782	64809805	11	+	27260157	RKO	viability	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	0.148907922308291	[]	[]	0	hSpCas9	negative selection	2813496
64809925	64809948	11	+	27260157	RKO	viability	GTGAGCTCGGGAACGTTGGTAGG	MEN1	ENSG00000133895	-0.793039065560293	[]	[]	-7	hSpCas9	negative selection	2832889
64809992	64810015	11	-	27260157	RKO	viability	GGACCTGGTGCTCCTTTCCTTGG	MEN1	ENSG00000133895	-0.608068637463344	[]	[]	-7	hSpCas9	negative selection	2833481
64810054	64810077	11	+	27260157	RKO	viability	ACGTCGTCGATGGAGCGCAGCGG	MEN1	ENSG00000133895	0.380361302013204	[]	[]	2	hSpCas9	negative selection	2834620
64809866	64809889	11	+	27260157	RKO	viability	CGGCCACGGGAAAGTAGGTGAGG	MEN1	ENSG00000133895	-1.77918540108815	[]	[]	-9	hSpCas9	negative selection	2838262
64809842	64809865	11	+	27260157	RKO	viability	AGAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-0.662939057626527	[]	[]	-7	hSpCas9	negative selection	2840429
64809975	64809998	11	+	27260157	RKO	viability	CTCCACGAAGCCCAGCACCAAGG	MEN1	ENSG00000133895	-0.556277078741707	[]	[]	-7	hSpCas9	negative selection	2840732
64810019	64810042	11	-	27260157	RKO	viability	TGCTGCCGAGCTGGGCCGAGAGG	MEN1	ENSG00000133895	0.301427046664155	[]	[]	1	hSpCas9	negative selection	2841520
64809797	64809820	11	+	27260157	RKO	viability	GGGACAGGTCGACGGCGCCTCGG	MEN1	ENSG00000133895	0.0646468258073917	[]	[]	0	hSpCas9	negative selection	2842051
64810013	64810036	11	-	27260157	RKO	viability	CGAGCTGGGCCGAGAGGAGCCGG	MEN1	ENSG00000133895	-1.33088689564862	[]	[]	-8	hSpCas9	negative selection	2844423
64810025	64810048	11	+	27260157	RKO	viability	GGCCCAGCTCGGCAGCAAACAGG	MEN1	ENSG00000133895	-1.11349134537053	[]	[]	-8	hSpCas9	negative selection	2845908
64810027	64810050	11	-	27260157	RKO	viability	CGCCTGTTTGCTGCCGAGCTGGG	MEN1	ENSG00000133895	0.916368203630056	[]	[]	8	hSpCas9	negative selection	2848269
64810004	64810027	11	+	27260157	RKO	viability	GCACCAGGTCCGGCTCCTCTCGG	MEN1	ENSG00000133895	-1.03085862019216	[]	[]	-8	hSpCas9	negative selection	2850450
64810052	64810075	11	-	27260157	RKO	viability	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	-0.89551347382405	[]	[]	-8	hSpCas9	negative selection	2872627
64809807	64809830	11	+	27260157	RKO	viability	GACGGCGCCTCGGATCTGGGCGG	MEN1	ENSG00000133895	-0.269426263592147	[]	[]	-1	hSpCas9	negative selection	2874559
64809778	64809801	11	-	27260157	RKO	viability	TCCCTCTATCCTCGAGAAGGGGG	MEN1	ENSG00000133895	-1.45673795400304	[]	[]	-8	hSpCas9	negative selection	2875571
64809749	64809772	11	-	27260157	SF268	viability	CAGCCGTGAGCTGGTGAAGAAGG	MEN1	ENSG00000133895	0.637387981988001	[]	[]	8	hSpCas9	negative selection	2884577
64809985	64810008	11	-	27260157	SF268	viability	GTGCTCCTTTCCTTGGTGCTGGG	MEN1	ENSG00000133895	0.94050104786026	[]	[]	9	hSpCas9	negative selection	2888311
64810044	64810067	11	+	27260157	SF268	viability	CAGGCGCACCACGTCGTCGATGG	MEN1	ENSG00000133895	1.3159774232655	[]	[]	9	hSpCas9	negative selection	2889448
64809782	64809805	11	+	27260157	SF268	viability	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.218684561482401	[]	[]	-2	hSpCas9	negative selection	2889626
64809925	64809948	11	+	27260157	SF268	viability	GTGAGCTCGGGAACGTTGGTAGG	MEN1	ENSG00000133895	-0.650540371803214	[]	[]	-5	hSpCas9	negative selection	2909019
64809992	64810015	11	-	27260157	SF268	viability	GGACCTGGTGCTCCTTTCCTTGG	MEN1	ENSG00000133895	0.836948705847402	[]	[]	9	hSpCas9	negative selection	2909611
64810054	64810077	11	+	27260157	SF268	viability	ACGTCGTCGATGGAGCGCAGCGG	MEN1	ENSG00000133895	0.75538162009368	[]	[]	8	hSpCas9	negative selection	2910750
64809866	64809889	11	+	27260157	SF268	viability	CGGCCACGGGAAAGTAGGTGAGG	MEN1	ENSG00000133895	-1.74900587336117	[]	[]	-8	hSpCas9	negative selection	2914392
64809842	64809865	11	+	27260157	SF268	viability	AGAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	0.520156123558361	[]	[]	8	hSpCas9	negative selection	2916559
64809975	64809998	11	+	27260157	SF268	viability	CTCCACGAAGCCCAGCACCAAGG	MEN1	ENSG00000133895	1.21684271629166	[]	[]	9	hSpCas9	negative selection	2916862
64810019	64810042	11	-	27260157	SF268	viability	TGCTGCCGAGCTGGGCCGAGAGG	MEN1	ENSG00000133895	0.702399545597603	[]	[]	8	hSpCas9	negative selection	2917650
64809797	64809820	11	+	27260157	SF268	viability	GGGACAGGTCGACGGCGCCTCGG	MEN1	ENSG00000133895	0.437688003084536	[]	[]	7	hSpCas9	negative selection	2918181
64810013	64810036	11	-	27260157	SF268	viability	CGAGCTGGGCCGAGAGGAGCCGG	MEN1	ENSG00000133895	-1.47875736455534	[]	[]	-8	hSpCas9	negative selection	2920553
64810025	64810048	11	+	27260157	SF268	viability	GGCCCAGCTCGGCAGCAAACAGG	MEN1	ENSG00000133895	0.320504971514158	[]	[]	4	hSpCas9	negative selection	2922038
64810027	64810050	11	-	27260157	SF268	viability	CGCCTGTTTGCTGCCGAGCTGGG	MEN1	ENSG00000133895	0.513947162804463	[]	[]	7	hSpCas9	negative selection	2924399
64810004	64810027	11	+	27260157	SF268	viability	GCACCAGGTCCGGCTCCTCTCGG	MEN1	ENSG00000133895	-0.761648372728198	[]	[]	-6	hSpCas9	negative selection	2926580
64810052	64810075	11	-	27260157	SF268	viability	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	0.887329247124269	[]	[]	9	hSpCas9	negative selection	2948757
64809807	64809830	11	+	27260157	SF268	viability	GACGGCGCCTCGGATCTGGGCGG	MEN1	ENSG00000133895	0.646921009815881	[]	[]	8	hSpCas9	negative selection	2950689
64809778	64809801	11	-	27260157	SF268	viability	TCCCTCTATCCTCGAGAAGGGGG	MEN1	ENSG00000133895	-0.263763686613385	[]	[]	-2	hSpCas9	negative selection	2951701
64810055	64810078	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACGTCGTCGATGGAGCGCAGCGG	MEN1	ENSG00000133895	-0.32251817573461117	[3,3]	[4,0]	-4	hSpCas9	positive selection	3001968
64809869	64809892	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGGCCTCACCTACTTTCCCGTGG	MEN1	ENSG00000133895	-0.6467922445531304	[4,4]	[3,1]	-7	hSpCas9	positive selection	3001969
64810052	64810075	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	-1.0012086676795462	[2,2]	[1,0]	-9	hSpCas9	positive selection	3001970
64809829	64809852	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-1.0345784602565065	[4,4]	[2,0]	-9	hSpCas9	positive selection	3001971
64810055	64810078	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACGTCGTCGATGGAGCGCAGCGG	MEN1	ENSG00000133895	0.05187332755839185	[3,3]	[4,0]	0	hSpCas9	positive selection	3069826
64809869	64809892	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGGCCTCACCTACTTTCCCGTGG	MEN1	ENSG00000133895	0.07647498884018245	[4,4]	[4,2]	1	hSpCas9	positive selection	3069827
64810052	64810075	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	-0.49419108262579114	[2,2]	[2,0]	-7	hSpCas9	positive selection	3069828
64809829	64809852	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-0.31178260767691934	[4,4]	[3,1]	-5	hSpCas9	positive selection	3069829
64805659	64805682		+	24336571	A375	resistance to PLX after 7 days	CTCGCCCGCCTCCAGCAAGCTGG	MEN1	ENSG00000133895	0.020962666304900734	[16,19]	[15,20]	0	hSpCas9	positive selection	3127130
64807933	64807956		+	24336571	A375	resistance to PLX after 7 days	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	-0.10111342925896061	[94,89]	[87,82]	-3	hSpCas9	positive selection	3127131
64808022	64808045		+	24336571	A375	resistance to PLX after 7 days	GGTGGACATCCCGGAGACCCAGG	MEN1	ENSG00000133895	0.18607986885338457	[3,8]	[7,6]	6	hSpCas9	positive selection	3127132
64805736	64805759		+	24336571	A375	resistance to PLX after 7 days	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.369914177528025	[41,41]	[32,30]	-9	hSpCas9	positive selection	3127133
64805659	64805682		+	24336571	A375	resistance to PLX after 14 days	CTCGCCCGCCTCCAGCAAGCTGG	MEN1	ENSG00000133895	0.42001669175583756	[18,15]	[8,11]	4	hSpCas9	positive selection	3184923
64807933	64807956		+	24336571	A375	resistance to PLX after 14 days	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	-0.45462012298883847	[91,92]	[27,34]	-5	hSpCas9	positive selection	3184924
64808022	64808045		+	24336571	A375	resistance to PLX after 14 days	GGTGGACATCCCGGAGACCCAGG	MEN1	ENSG00000133895	-0.4482263682852403	[5,7]	[2,1]	-5	hSpCas9	positive selection	3184925
64805736	64805759		+	24336571	A375	resistance to PLX after 14 days	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.8085212215742473	[28,26]	[7,6]	-8	hSpCas9	positive selection	3184926
64805659	64805682		+	24336571	A375	viability after 7 days	CTCGCCCGCCTCCAGCAAGCTGG	MEN1	ENSG00000133895	-0.124365724220038	[20]	[16,19]	-2	hSpCas9	negative selection	3242716
64807933	64807956		+	24336571	A375	viability after 7 days	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.8253265458249368	[54]	[94,89]	9	hSpCas9	negative selection	3242717
64808022	64808045		+	24336571	A375	viability after 7 days	GGTGGACATCCCGGAGACCCAGG	MEN1	ENSG00000133895	-0.5936850304174486	[10]	[3,8]	-7	hSpCas9	negative selection	3242718
64805736	64805759		+	24336571	A375	viability after 7 days	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.3154111861585387	[54]	[41,41]	-4	hSpCas9	negative selection	3242719
64805659	64805682		+	24336571	A375	viability after 14 days	CTCGCCCGCCTCCAGCAAGCTGG	MEN1	ENSG00000133895	-0.20872506134682334	[20]	[18,15]	-2	hSpCas9	negative selection	3300509
64807933	64807956		+	24336571	A375	viability after 14 days	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.839543449756357	[54]	[91,92]	9	hSpCas9	negative selection	3300510
64808022	64808045		+	24336571	A375	viability after 14 days	GGTGGACATCCCGGAGACCCAGG	MEN1	ENSG00000133895	-0.43960517296974405	[10]	[5,7]	-5	hSpCas9	negative selection	3300511
64805736	64805759		+	24336571	A375	viability after 14 days	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.8730778380332718	[54]	[28,26]	-8	hSpCas9	negative selection	3300512
64807933	64807956	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	-1.05555674383852	[317,317]	[0,0]	-7	hSpCas9	positive selection	3379026
64807932	64807955	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	0.8310614567437372	[85,85]	[0,0]	4	hSpCas9	positive selection	3379027
64805755	64805778	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-2.051012818693572	[633,633]	[0,0]	-9	hSpCas9	positive selection	3379028
64810054	64810077	11	+	26780180	HT29	viability (Avana library 4 designs)	ACGTCGTCGATGGAGCGCAGCGG	MEN1	ENSG00000133895	1.88990227865557	[]	[]	7	hSpCas9	negative selection	3439702
64809869	64809892	11	-	26780180	HT29	viability (Avana library 4 designs)	CGGCCTCACCTACTTTCCCGTGG	MEN1	ENSG00000133895	2.64756070157878	[]	[]	8	hSpCas9	negative selection	3439703
64810052	64810075	11	-	26780180	HT29	viability (Avana library 4 designs)	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	2.47245928805331	[]	[]	8	hSpCas9	negative selection	3439704
64809828	64809851	11	+	26780180	HT29	viability (Avana library 4 designs)	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	2.76505609267834	[]	[]	8	hSpCas9	negative selection	3439705
64810052	64810075	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	-1.36695445924747	[]	[]	-2	hSpCas9	negative selection	3529575
64810054	64810077	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACGTCGTCGATGGAGCGCAGCGG	MEN1	ENSG00000133895	-0.490195365994065	[]	[]	0	hSpCas9	negative selection	3529576
64809828	64809851	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-2.38123738456591	[]	[]	-3	hSpCas9	negative selection	3529577
64809869	64809892	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGGCCTCACCTACTTTCCCGTGG	MEN1	ENSG00000133895	-6.9315552590566	[]	[]	-6	hSpCas9	negative selection	3529578
64809877	64809900	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	-0.329081788224157	[]	[]	0	hSpCas9	negative selection	3529579
64808001	64808024	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATGATCCTCAGACAGGGCGAGG	MEN1	ENSG00000133895	-1.54240098008373	[]	[]	-2	hSpCas9	negative selection	3529580
64810052	64810075	11	-	26780180	A375	viability (Avana lentiGuide)	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	12.7110690881987	[]	[]	7	hSpCas9	negative selection	3638234
64810054	64810077	11	+	26780180	A375	viability (Avana lentiGuide)	ACGTCGTCGATGGAGCGCAGCGG	MEN1	ENSG00000133895	17.4819950640443	[]	[]	8	hSpCas9	negative selection	3638235
64809828	64809851	11	+	26780180	A375	viability (Avana lentiGuide)	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	29.6438353220665	[]	[]	9	hSpCas9	negative selection	3638236
64809869	64809892	11	-	26780180	A375	viability (Avana lentiGuide)	CGGCCTCACCTACTTTCCCGTGG	MEN1	ENSG00000133895	18.9794491916243	[]	[]	8	hSpCas9	negative selection	3638237
64809877	64809900	11	+	26780180	A375	viability (Avana lentiGuide)	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	18.4811519345832	[]	[]	8	hSpCas9	negative selection	3638238
64808001	64808024	11	+	26780180	A375	viability (Avana lentiGuide)	CATGATCCTCAGACAGGGCGAGG	MEN1	ENSG00000133895	18.6760806569441	[]	[]	8	hSpCas9	negative selection	3638239
64810052	64810075	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	-1.0398619949183034	[4]	[1,1]	-9	hSpCas9	positive selection	3746893
64810054	64810077	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACGTCGTCGATGGAGCGCAGCGG	MEN1	ENSG00000133895	-0.6806446186925028	[4]	[2,1]	-7	hSpCas9	positive selection	3746894
64809828	64809851	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-0.5240505598274019	[4]	[3,2]	-6	hSpCas9	positive selection	3746895
64809869	64809892	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGCCTCACCTACTTTCCCGTGG	MEN1	ENSG00000133895	-1.40523552284914	[5]	[2,0]	-9	hSpCas9	positive selection	3746896
64809877	64809900	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	-0.05720482657216766	[5]	[4,4]	-1	hSpCas9	positive selection	3746897
64808001	64808024	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGATCCTCAGACAGGGCGAGG	MEN1	ENSG00000133895	-0.11442726199097353	[4]	[3,4]	-2	hSpCas9	positive selection	3746898
64810052	64810075	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCGCTCCATCGACGACGTGG	MEN1	ENSG00000133895	-0.8429099583260837	[4]	[1,1]	-8	hSpCas9	positive selection	3855500
64810054	64810077	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACGTCGTCGATGGAGCGCAGCGG	MEN1	ENSG00000133895	-0.6194456363088624	[5]	[3,1]	-7	hSpCas9	positive selection	3855501
64809828	64809851	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-1.3217350537438315	[6]	[1,1]	-9	hSpCas9	positive selection	3855502
64809869	64809892	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGCCTCACCTACTTTCCCGTGG	MEN1	ENSG00000133895	-0.8592737723523427	[7]	[3,2]	-8	hSpCas9	positive selection	3855503
64809877	64809900	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	-0.6202194502911624	[5]	[0,4]	-7	hSpCas9	positive selection	3855504
64808001	64808024	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGATCCTCAGACAGGGCGAGG	MEN1	ENSG00000133895	-1.698995226783649	[4]	[0,0]	-9	hSpCas9	positive selection	3855505
64807632	64807655	11	-	26780180	A375	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.99901765504679	[]	[]	4	hSpCas9	negative selection	3960983
64805755	64805778	11	-	26780180	A375	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.907617984882552	[]	[]	4	hSpCas9	negative selection	3960984
64807933	64807956	11	+	26780180	A375	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	1.01992263528835	[]	[]	5	hSpCas9	negative selection	3960985
64807932	64807955	11	-	26780180	A375	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	1.39354991577028	[]	[]	7	hSpCas9	negative selection	3960986
64807572	64807595	11	-	26780180	A375	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	1.5213361488556	[]	[]	8	hSpCas9	negative selection	3960987
64805736	64805759	11	+	26780180	A375	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	1.4373651879739	[]	[]	8	hSpCas9	negative selection	3960988
64807632	64807655	11	-	26780180	HT29	viability (GeCKOv2 library)	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	1.46513604951602	[]	[]	7	hSpCas9	negative selection	4068949
64805755	64805778	11	-	26780180	HT29	viability (GeCKOv2 library)	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.0849145576815593	[]	[]	-2	hSpCas9	negative selection	4068950
64807933	64807956	11	+	26780180	HT29	viability (GeCKOv2 library)	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.912879027625244	[]	[]	4	hSpCas9	negative selection	4068951
64807932	64807955	11	-	26780180	HT29	viability (GeCKOv2 library)	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	0.616890342348204	[]	[]	2	hSpCas9	negative selection	4068952
64807572	64807595	11	-	26780180	HT29	viability (GeCKOv2 library)	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.934531825886889	[]	[]	4	hSpCas9	negative selection	4068953
64805736	64805759	11	+	26780180	HT29	viability (GeCKOv2 library)	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.809032886330111	[]	[]	3	hSpCas9	negative selection	4068954
64805659	64805682	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCGCCCGCCTCCAGCAAGCTGG	MEN1	ENSG00000133895	0.12342273640994553	[4]	[2,3]	3	hSpCas9	positive selection	4151444
64807933	64807956	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.1507532035141177	[5]	[3,4]	4	hSpCas9	positive selection	4151445
64808022	64808045	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTGGACATCCCGGAGACCCAGG	MEN1	ENSG00000133895	-0.8088310550858575	[4]	[1,0]	-9	hSpCas9	positive selection	4151446
64805736	64805759	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.31779730875529966	[5]	[2,2]	-7	hSpCas9	positive selection	4151447
64805659	64805682	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCGCCCGCCTCCAGCAAGCTGG	MEN1	ENSG00000133895	-0.9971058635802126	[4]	[0,0,1,0]	-9	hSpCas9	positive selection	4215466
64807933	64807956	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.8714903774629335	[5]	[4,4,3,3]	6	hSpCas9	positive selection	4215467
64808022	64808045	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTGGACATCCCGGAGACCCAGG	MEN1	ENSG00000133895	-0.46861206274841877	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4215468
64805736	64805759	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.6115152316085374	[5]	[1,1,0,0]	-8	hSpCas9	positive selection	4215469
64807632	64807655	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.8227895460877939	[1]	[0,0]	-9	hSpCas9	positive selection	4282545
64807572	64807595	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.1766879513919312	[3]	[3,1]	-4	hSpCas9	positive selection	4282546
64805736	64805759	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.4277261738431804	[3]	[2,0]	-7	hSpCas9	positive selection	4282547
64807933	64807956	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.3530875736874276	[3]	[2,3]	7	hSpCas9	positive selection	4346803
64807932	64807955	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	0.07252879662485961	[2]	[2,1]	1	hSpCas9	positive selection	4346804
64805755	64805778	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.3934083587644809	[5]	[5,4]	7	hSpCas9	positive selection	4346805
64807934	64807956	11	+	27760321	OCIAML3	viability	TCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	-0.16336111796842245	[1495,1366]	[931,1086]	-2	hSpCas9	negative selection	4417753
64807975	64807997	11	-	27760321	OCIAML3	viability	GGTAGTGTTTGGGCCCAATGGG	MEN1	ENSG00000133895	-0.9354736312563479	[204,254]	[112,71]	-7	hSpCas9	negative selection	4417754
64809698	64809720	11	-	27760321	OCIAML3	viability	CGCTCCTACTTCAAGGATCGGG	MEN1	ENSG00000133895	-1.7176524643957278	[651,531]	[123,160]	-8	hSpCas9	negative selection	4417755
64809843	64809865	11	+	27760321	OCIAML3	viability	GAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-2.000675168546931	[227,167]	[33,43]	-9	hSpCas9	negative selection	4417756
64809862	64809884	11	+	27760321	OCIAML3	viability	AGGTCGGCCACGGGAAAGTAGG	MEN1	ENSG00000133895	-2.4864304155560593	[384,328]	[30,73]	-9	hSpCas9	negative selection	4417757
64807934	64807956	11	+	27760321	OCIAML2	viability	TCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.10825057346731048	[1495,1366]	[1034,1527]	1	hSpCas9	negative selection	4501216
64807975	64807997	11	-	27760321	OCIAML2	viability	GGTAGTGTTTGGGCCCAATGGG	MEN1	ENSG00000133895	-0.6220412737957046	[204,254]	[130,110]	-6	hSpCas9	negative selection	4501217
64809698	64809720	11	-	27760321	OCIAML2	viability	CGCTCCTACTTCAAGGATCGGG	MEN1	ENSG00000133895	-0.4298265091931177	[651,531]	[351,355]	-5	hSpCas9	negative selection	4501218
64809843	64809865	11	+	27760321	OCIAML2	viability	GAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-2.45432034361766	[227,167]	[34,20]	-9	hSpCas9	negative selection	4501219
64809862	64809884	11	+	27760321	OCIAML2	viability	AGGTCGGCCACGGGAAAGTAGG	MEN1	ENSG00000133895	-3.086843412699299	[384,328]	[29,38]	-9	hSpCas9	negative selection	4501220
64807934	64807956	11	+	27760321	MV411	viability	TCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.05627123089591657	[1495,1366]	[757,1317]	0	hSpCas9	negative selection	4584679
64807975	64807997	11	-	27760321	MV411	viability	GGTAGTGTTTGGGCCCAATGGG	MEN1	ENSG00000133895	0.772817471180204	[204,254]	[373,94]	5	hSpCas9	negative selection	4584680
64809698	64809720	11	-	27760321	MV411	viability	CGCTCCTACTTCAAGGATCGGG	MEN1	ENSG00000133895	-0.9279567518230463	[651,531]	[81,387]	-6	hSpCas9	negative selection	4584681
64809843	64809865	11	+	27760321	MV411	viability	GAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-2.493994440663584	[227,167]	[0,55]	-9	hSpCas9	negative selection	4584682
64809862	64809884	11	+	27760321	MV411	viability	AGGTCGGCCACGGGAAAGTAGG	MEN1	ENSG00000133895	0.8114094161139325	[384,328]	[567,177]	6	hSpCas9	negative selection	4584683
64807934	64807956	11	+	27760321	HL60	viability	TCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.3697273789117155	[1495,1366]	[1586,1428]	4	hSpCas9	negative selection	4668142
64807975	64807997	11	-	27760321	HL60	viability	GGTAGTGTTTGGGCCCAATGGG	MEN1	ENSG00000133895	-0.43703825778555383	[204,254]	[122,158]	-5	hSpCas9	negative selection	4668143
64809698	64809720	11	-	27760321	HL60	viability	CGCTCCTACTTCAAGGATCGGG	MEN1	ENSG00000133895	-0.8924352019577502	[651,531]	[298,216]	-7	hSpCas9	negative selection	4668144
64809843	64809865	11	+	27760321	HL60	viability	GAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-1.3504554186337425	[227,167]	[90,32]	-8	hSpCas9	negative selection	4668145
64809862	64809884	11	+	27760321	HL60	viability	AGGTCGGCCACGGGAAAGTAGG	MEN1	ENSG00000133895	-0.42328231046716913	[384,328]	[275,153]	-5	hSpCas9	negative selection	4668146
64807934	64807956	11	+	27760321	HT1080	viability	TCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.588917842854735	[1366,1066]	[733,723]	3	hSpCas9	negative selection	4751605
64807975	64807997	11	-	27760321	HT1080	viability	GGTAGTGTTTGGGCCCAATGGG	MEN1	ENSG00000133895	-0.6866186522747021	[254,198]	[38,74]	-3	hSpCas9	negative selection	4751606
64809698	64809720	11	-	27760321	HT1080	viability	CGCTCCTACTTCAAGGATCGGG	MEN1	ENSG00000133895	0.15608276332307935	[531,414]	[118,309]	0	hSpCas9	negative selection	4751607
64809843	64809865	11	+	27760321	HT1080	viability	GAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-1.2482322644475408	[167,130]	[15,34]	-5	hSpCas9	negative selection	4751608
64809862	64809884	11	+	27760321	HT1080	viability	AGGTCGGCCACGGGAAAGTAGG	MEN1	ENSG00000133895	0.2890862222648658	[328,256]	[60,231]	1	hSpCas9	negative selection	4751609
64807934	64807956	11	+	27760321	HT29	viability after 7 days	TCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	-0.06619828344940815	[1366,1066]	[1741,1446,1332]	-1	hSpCas9	negative selection	4835068
64807975	64807997	11	-	27760321	HT29	viability after 7 days	GGTAGTGTTTGGGCCCAATGGG	MEN1	ENSG00000133895	-0.5995253684984175	[254,198]	[289,157,144]	-7	hSpCas9	negative selection	4835069
64809698	64809720	11	-	27760321	HT29	viability after 7 days	CGCTCCTACTTCAAGGATCGGG	MEN1	ENSG00000133895	0.6980647856877844	[531,414]	[1062,947,961]	9	hSpCas9	negative selection	4835070
64809843	64809865	11	+	27760321	HT29	viability after 7 days	GAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-0.14329212176851236	[167,130]	[263,138,132]	-2	hSpCas9	negative selection	4835071
64809862	64809884	11	+	27760321	HT29	viability after 7 days	AGGTCGGCCACGGGAAAGTAGG	MEN1	ENSG00000133895	0.2067061140961447	[328,256]	[637,238,454]	3	hSpCas9	negative selection	4835072
64807934	64807956	11	+	27760321	HT29	viability after 25 days	TCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.32437049988352906	[1366,1066]	[1345,1587,2378]	3	hSpCas9	negative selection	4918531
64807975	64807997	11	-	27760321	HT29	viability after 25 days	GGTAGTGTTTGGGCCCAATGGG	MEN1	ENSG00000133895	0.0424761325147075	[254,198]	[158,337,315]	0	hSpCas9	negative selection	4918532
64809698	64809720	11	-	27760321	HT29	viability after 25 days	CGCTCCTACTTCAAGGATCGGG	MEN1	ENSG00000133895	0.4747216813536078	[531,414]	[716,614,944]	5	hSpCas9	negative selection	4918533
64809843	64809865	11	+	27760321	HT29	viability after 25 days	GAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	0.09104275239668547	[167,130]	[120,129,311]	0	hSpCas9	negative selection	4918534
64809862	64809884	11	+	27760321	HT29	viability after 25 days	AGGTCGGCCACGGGAAAGTAGG	MEN1	ENSG00000133895	-0.2894786519743037	[328,256]	[240,313,267]	-3	hSpCas9	negative selection	4918535
64807934	64807956	11	+	27760321	HT29	viability after 22 days	TCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.09717740492717764	[1366,1066]	[1385,1523,1608]	0	hSpCas9	negative selection	5001994
64807975	64807997	11	-	27760321	HT29	viability after 22 days	GGTAGTGTTTGGGCCCAATGGG	MEN1	ENSG00000133895	-0.3418017852179117	[254,198]	[163,287,169]	-3	hSpCas9	negative selection	5001995
64809698	64809720	11	-	27760321	HT29	viability after 22 days	CGCTCCTACTTCAAGGATCGGG	MEN1	ENSG00000133895	0.5093299369324786	[531,414]	[686,646,1007]	5	hSpCas9	negative selection	5001996
64809843	64809865	11	+	27760321	HT29	viability after 22 days	GAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-0.11149406371735049	[167,130]	[167,117,193]	-1	hSpCas9	negative selection	5001997
64809862	64809884	11	+	27760321	HT29	viability after 22 days	AGGTCGGCCACGGGAAAGTAGG	MEN1	ENSG00000133895	0.11377425658282403	[328,256]	[370,306,421]	1	hSpCas9	negative selection	5001998
64807934	64807956	11	+	27760321	HT29	viability after 19 days	TCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.4557502802164175	[1366,1066]	[1991,1291,2429]	4	hSpCas9	negative selection	5085457
64807975	64807997	11	-	27760321	HT29	viability after 19 days	GGTAGTGTTTGGGCCCAATGGG	MEN1	ENSG00000133895	-0.6133751335614183	[254,198]	[291,172,60]	-5	hSpCas9	negative selection	5085458
64809698	64809720	11	-	27760321	HT29	viability after 19 days	CGCTCCTACTTCAAGGATCGGG	MEN1	ENSG00000133895	0.5707032339283453	[531,414]	[600,609,1165]	6	hSpCas9	negative selection	5085459
64809843	64809865	11	+	27760321	HT29	viability after 19 days	GAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-0.020642613329165282	[167,130]	[157,166,178]	0	hSpCas9	negative selection	5085460
64809862	64809884	11	+	27760321	HT29	viability after 19 days	AGGTCGGCCACGGGAAAGTAGG	MEN1	ENSG00000133895	-0.224068074053066	[328,256]	[395,243,233]	-2	hSpCas9	negative selection	5085461
64807934	64807956	11	+	27760321	HT29	viability after 16 days	TCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.37804691466149953	[1366,1066]	[2033,1585,1717]	4	hSpCas9	negative selection	5168920
64807975	64807997	11	-	27760321	HT29	viability after 16 days	GGTAGTGTTTGGGCCCAATGGG	MEN1	ENSG00000133895	-0.1664922934474259	[254,198]	[287,212,183]	-2	hSpCas9	negative selection	5168921
64809698	64809720	11	-	27760321	HT29	viability after 16 days	CGCTCCTACTTCAAGGATCGGG	MEN1	ENSG00000133895	0.5527935694551133	[531,414]	[862,594,885]	6	hSpCas9	negative selection	5168922
64809843	64809865	11	+	27760321	HT29	viability after 16 days	GAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-0.22575538450408184	[167,130]	[140,175,110]	-3	hSpCas9	negative selection	5168923
64809862	64809884	11	+	27760321	HT29	viability after 16 days	AGGTCGGCCACGGGAAAGTAGG	MEN1	ENSG00000133895	-0.03672061643367247	[328,256]	[397,285,282]	0	hSpCas9	negative selection	5168924
64807934	64807956	11	+	27760321	HT29	viability after 13 days	TCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.1404524813180814	[1366,1066]	[1542,1391,1722]	1	hSpCas9	negative selection	5252383
64807975	64807997	11	-	27760321	HT29	viability after 13 days	GGTAGTGTTTGGGCCCAATGGG	MEN1	ENSG00000133895	-0.4772554462043167	[254,198]	[210,142,211]	-5	hSpCas9	negative selection	5252384
64809698	64809720	11	-	27760321	HT29	viability after 13 days	CGCTCCTACTTCAAGGATCGGG	MEN1	ENSG00000133895	0.36983771797239995	[531,414]	[551,873,703]	5	hSpCas9	negative selection	5252385
64809843	64809865	11	+	27760321	HT29	viability after 13 days	GAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	0.10462575116249773	[167,130]	[44,247,261]	1	hSpCas9	negative selection	5252386
64809862	64809884	11	+	27760321	HT29	viability after 13 days	AGGTCGGCCACGGGAAAGTAGG	MEN1	ENSG00000133895	-0.2317645209966605	[328,256]	[204,329,330]	-3	hSpCas9	negative selection	5252387
64807934	64807956	11	+	27760321	HT29	viability after 10 days	TCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.2930404529397188	[1366,1066]	[1804,1468,2289]	4	hSpCas9	negative selection	5335846
64807975	64807997	11	-	27760321	HT29	viability after 10 days	GGTAGTGTTTGGGCCCAATGGG	MEN1	ENSG00000133895	-0.04900923523978107	[254,198]	[255,445,127]	0	hSpCas9	negative selection	5335847
64809698	64809720	11	-	27760321	HT29	viability after 10 days	CGCTCCTACTTCAAGGATCGGG	MEN1	ENSG00000133895	0.571255244715089	[531,414]	[576,1153,910]	7	hSpCas9	negative selection	5335848
64809843	64809865	11	+	27760321	HT29	viability after 10 days	GAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-0.5998796472224921	[167,130]	[45,188,135]	-6	hSpCas9	negative selection	5335849
64809862	64809884	11	+	27760321	HT29	viability after 10 days	AGGTCGGCCACGGGAAAGTAGG	MEN1	ENSG00000133895	-0.2023663051646888	[328,256]	[379,152,413]	-3	hSpCas9	negative selection	5335850
64807934	64807956	11	+	27760321	MOLM13	viability	TCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	-1.4623499559373332	[1495,1366]	[178,389]	-7	hSpCas9	negative selection	5419309
64807975	64807997	11	-	27760321	MOLM13	viability	GGTAGTGTTTGGGCCCAATGGG	MEN1	ENSG00000133895	-0.7775623092826587	[204,254]	[0,140]	-5	hSpCas9	negative selection	5419310
64809698	64809720	11	-	27760321	MOLM13	viability	CGCTCCTACTTCAAGGATCGGG	MEN1	ENSG00000133895	-0.7231220609076093	[651,531]	[149,244]	-4	hSpCas9	negative selection	5419311
64809843	64809865	11	+	27760321	MOLM13	viability	GAGGGCGGCGATGATAGACAGG	MEN1	ENSG00000133895	-1.6362891617389885	[227,167]	[13,53]	-7	hSpCas9	negative selection	5419312
64809862	64809884	11	+	27760321	MOLM13	viability	AGGTCGGCCACGGGAAAGTAGG	MEN1	ENSG00000133895	-1.36959229130938	[384,328]	[0,142]	-7	hSpCas9	negative selection	5419313
64810092	64810115	11	+	27661255	K562	viability	GGCGGCCTTCAGCCCCATGGCGG	MEN1	ENSG00000133895	0.425572805859296	[618,699]	[766,653]	9	dCas9-KRAB	negative selection	5492965
64810338	64810361	11	+	27661255	K562	viability	GGGACGCCCGGTACCCGATGGGG	MEN1	ENSG00000133895	0.05749638957832899	[758,898]	[733,646]	2	dCas9-KRAB	negative selection	5492966
64810461	64810484	11	+	27661255	K562	viability	GGTCAAGCCCCCAAACCCCAAGG	MEN1	ENSG00000133895	-0.059885048810900676	[601,608]	[525,410]	-2	dCas9-KRAB	negative selection	5492967
64810529	64810552	11	-	27661255	K562	viability	GTGCGCCGCGGTGCCTAGTGTGG	MEN1	ENSG00000133895	0.09720467243175565	[856,845]	[791,672]	3	dCas9-KRAB	negative selection	5492968
64807632	64807655	11	-	27260156	BXPC3	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.2590389310669159	[93]	[154,81,100,130]	5	hSpCas9	negative selection	5555005
64807572	64807595	11	-	27260156	BXPC3	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.5188204724590738	[743]	[1121,1023,1074,1249]	9	hSpCas9	negative selection	5555006
64805736	64805759	11	+	27260156	BXPC3	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.2634743979399758	[496]	[598,612,704,571]	6	hSpCas9	negative selection	5555007
64807933	64807956	11	+	27260156	BXPC3	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.20817718913380534	[689]	[803,729,779,1048]	4	hSpCas9	negative selection	5619263
64807932	64807955	11	-	27260156	BXPC3	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	0.4049056955714393	[286]	[370,422,327,473]	8	hSpCas9	negative selection	5619264
64805755	64805778	11	-	27260156	BXPC3	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.0530547095710161	[2308]	[1870,2402,2767,3114]	1	hSpCas9	negative selection	5619265
64807632	64807655	11	-	27260156	A673	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.15530868092179828	[93]	[157,94,128,124]	3	hSpCas9	negative selection	5676256
64807572	64807595	11	-	27260156	A673	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.0716513558235462	[743]	[842,1149,879,859]	1	hSpCas9	negative selection	5676257
64805736	64805759	11	+	27260156	A673	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.5179229596946636	[496]	[985,825,824,791]	9	hSpCas9	negative selection	5676258
64807933	64807956	11	+	27260156	A673	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.34152460709050436	[689]	[1180,1148,854,1024]	7	hSpCas9	negative selection	5740514
64807932	64807955	11	-	27260156	A673	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.11361610044411763	[286]	[363,336,254,322]	-3	hSpCas9	negative selection	5740515
64805755	64805778	11	-	27260156	A673	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.10499089203137357	[2308]	[2584,2271,2475,3006]	-3	hSpCas9	negative selection	5740516
64807632	64807655	11	-	27260156	A375	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.8949718124026957	[93]	[67,46,84,36]	-8	hSpCas9	negative selection	5797507
64807572	64807595	11	-	27260156	A375	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.4525964800924509	[743]	[542,1018,529,512]	-6	hSpCas9	negative selection	5797508
64805736	64805759	11	+	27260156	A375	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.200481915900814	[496]	[620,529,421,455]	-3	hSpCas9	negative selection	5797509
64807933	64807956	11	+	27260156	A375	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.49016579549942174	[689]	[1194,1372,972,1028]	7	hSpCas9	negative selection	5861765
64807932	64807955	11	-	27260156	A375	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.6484652890073295	[286]	[291,334,58,188]	-7	hSpCas9	negative selection	5861766
64805755	64805778	11	-	27260156	A375	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.014325351519707485	[2308]	[2691,3105,2780,2397]	0	hSpCas9	negative selection	5861767
64807632	64807655	11	-	27260156	COLO741	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-1.0431091715079197	[93]	[39,71,60]	-9	hSpCas9	negative selection	5918758
64807572	64807595	11	-	27260156	COLO741	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.1765765937253484	[743]	[1201,1131,909]	4	hSpCas9	negative selection	5918759
64805736	64805759	11	+	27260156	COLO741	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.46825630212937774	[496]	[819,961,848]	8	hSpCas9	negative selection	5918760
64807933	64807956	11	+	27260156	COLO741	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.1891904503658718	[689]	[1159,1013,862]	4	hSpCas9	negative selection	5983016
64807932	64807955	11	-	27260156	COLO741	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.27876944633483114	[286]	[347,232,326]	-5	hSpCas9	negative selection	5983017
64805755	64805778	11	-	27260156	COLO741	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.09315363378135322	[2308]	[3527,3034,2919]	2	hSpCas9	negative selection	5983018
64807632	64807655	11	-	27260156	CAL120	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.11150872549717228	[93]	[42,223,99]	1	hSpCas9	negative selection	6040009
64807572	64807595	11	-	27260156	CAL120	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.19849045673109555	[743]	[1197,884,1122]	3	hSpCas9	negative selection	6040010
64805736	64805759	11	+	27260156	CAL120	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.34823038645600485	[496]	[646,1103,592]	5	hSpCas9	negative selection	6040011
64807933	64807956	11	+	27260156	CAL120	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.03358138377077047	[689]	[882,885,867]	0	hSpCas9	negative selection	6104267
64807932	64807955	11	-	27260156	CAL120	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.4677854245639679	[286]	[266,198,308]	-6	hSpCas9	negative selection	6104268
64805755	64805778	11	-	27260156	CAL120	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.28319723336826375	[2308]	[4394,3225,3010]	4	hSpCas9	negative selection	6104269
64807632	64807655	11	-	27260156	CADOES1	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.17358473430694543	[93]	[32,146,60,68]	-3	hSpCas9	negative selection	6161260
64807572	64807595	11	-	27260156	CADOES1	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.1705211375358926	[743]	[652,504,684,615]	-3	hSpCas9	negative selection	6161261
64805736	64805759	11	+	27260156	CADOES1	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.3833759353442078	[496]	[269,357,350,441]	-6	hSpCas9	negative selection	6161262
64807933	64807956	11	+	27260156	CADOES1	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.4324341504121306	[689]	[833,964,835,827]	7	hSpCas9	negative selection	6225518
64807932	64807955	11	-	27260156	CADOES1	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.6511667407819703	[286]	[264,120,111,181]	-8	hSpCas9	negative selection	6225519
64805755	64805778	11	-	27260156	CADOES1	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.0031011711288391197	[2308]	[2099,1968,2136,2373]	0	hSpCas9	negative selection	6225520
64807632	64807655	11	-	27260156	EWS502	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.04065480612866068	[93]	[80,74,75,161]	0	hSpCas9	negative selection	6282511
64807572	64807595	11	-	27260156	EWS502	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.34439539711509004	[743]	[901,929,1109,1077]	6	hSpCas9	negative selection	6282512
64805736	64805759	11	+	27260156	EWS502	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.4903242164511393	[496]	[567,809,818,779]	8	hSpCas9	negative selection	6282513
64807933	64807956	11	+	27260156	EWS502	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.3044164593670865	[689]	[849,850,925,994]	5	hSpCas9	negative selection	6346769
64807932	64807955	11	-	27260156	EWS502	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	0.3156324419638526	[286]	[345,300,567,300]	5	hSpCas9	negative selection	6346770
64805755	64805778	11	-	27260156	EWS502	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.0829236540525562	[2308]	[2113,2238,3362,2727]	1	hSpCas9	negative selection	6346771
64807632	64807655	11	-	27260156	EW8	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.15777297202420026	[93]	[54,46,63,105]	-3	hSpCas9	negative selection	6403762
64807572	64807595	11	-	27260156	EW8	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.18839470635637912	[743]	[742,637,573,815]	3	hSpCas9	negative selection	6403763
64805736	64805759	11	+	27260156	EW8	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.013593703961732359	[496]	[462,388,342,446]	0	hSpCas9	negative selection	6403764
64807933	64807956	11	+	27260156	EW8	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.3119557357040478	[689]	[785,645,619,744]	6	hSpCas9	negative selection	6468020
64807932	64807955	11	-	27260156	EW8	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.5561970989715666	[286]	[113,182,160,168]	-7	hSpCas9	negative selection	6468021
64805755	64805778	11	-	27260156	EW8	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.1691939493282888	[2308]	[2240,2210,1674,2370]	3	hSpCas9	negative selection	6468022
64807632	64807655	11	-	27260156	CORL105	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.10703990724403134	[93]	[135,35,145,99]	-2	hSpCas9	negative selection	6525013
64807572	64807595	11	-	27260156	CORL105	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.08530149986975677	[743]	[817,981,1124,797]	1	hSpCas9	negative selection	6525014
64805736	64805759	11	+	27260156	CORL105	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.19179840420425126	[496]	[691,640,811,537]	3	hSpCas9	negative selection	6525015
64807933	64807956	11	+	27260156	CORL105	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.3241438367952366	[689]	[911,935,1460,804]	6	hSpCas9	negative selection	6589271
64807932	64807955	11	-	27260156	CORL105	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	0.035165263284473	[286]	[326,322,358,369]	0	hSpCas9	negative selection	6589272
64805755	64805778	11	-	27260156	CORL105	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.22993664041146378	[2308]	[2107,2329,2581,2234]	-4	hSpCas9	negative selection	6589273
64807632	64807655	11	-	27260156	HS294T	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.15801754219642605	[93]	[16,59,29,21]	-2	hSpCas9	negative selection	6646264
64807572	64807595	11	-	27260156	HS294T	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.030433022917769725	[743]	[188,263,325,428]	0	hSpCas9	negative selection	6646265
64805736	64805759	11	+	27260156	HS294T	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.27809434259253674	[496]	[225,265,174,269]	4	hSpCas9	negative selection	6646266
64807933	64807956	11	+	27260156	HS294T	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.4285383888144265	[689]	[508,336,236,333]	6	hSpCas9	negative selection	6710522
64807932	64807955	11	-	27260156	HS294T	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.04865617757263774	[286]	[92,91,131,114]	0	hSpCas9	negative selection	6710523
64805755	64805778	11	-	27260156	HS294T	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.009406746188987292	[2308]	[841,768,963,1051]	0	hSpCas9	negative selection	6710524
64807632	64807655	11	-	27260156	HCC44	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.16709041023717308	[93]	[134,51,201,112]	2	hSpCas9	negative selection	6767515
64807572	64807595	11	-	27260156	HCC44	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.12609008351985151	[743]	[1036,712,1033,940]	2	hSpCas9	negative selection	6767516
64805736	64805759	11	+	27260156	HCC44	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.5273069388555464	[496]	[911,734,863,753]	8	hSpCas9	negative selection	6767517
64807933	64807956	11	+	27260156	HCC44	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	-0.004833063441467167	[689]	[885,579,938,765]	0	hSpCas9	negative selection	6831773
64807932	64807955	11	-	27260156	HCC44	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	0.022736467701479857	[286]	[324,411,238,312]	0	hSpCas9	negative selection	6831774
64805755	64805778	11	-	27260156	HCC44	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.29270396690811484	[2308]	[3839,2336,4254,2716]	5	hSpCas9	negative selection	6831775
64807632	64807655	11	-	27260156	G402	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.06220736483188105	[93]	[85,146,121,83]	-1	hSpCas9	negative selection	6888766
64807572	64807595	11	-	27260156	G402	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.11718980573701854	[743]	[1051,808,841,678]	-1	hSpCas9	negative selection	6888767
64805736	64805759	11	+	27260156	G402	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.5423697587747994	[496]	[1245,777,866,693]	6	hSpCas9	negative selection	6888768
64807933	64807956	11	+	27260156	G402	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.45822201953677333	[689]	[1343,1569,1018,759]	6	hSpCas9	negative selection	6953024
64807932	64807955	11	-	27260156	G402	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.36976933175225546	[286]	[532,225,294,73]	-5	hSpCas9	negative selection	6953025
64805755	64805778	11	-	27260156	G402	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.30971934143978785	[2308]	[3566,3063,3417,3872]	4	hSpCas9	negative selection	6953026
64807632	64807655	11	-	27260156	L33	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.18683840038535582	[93]	[154,24,47,133]	4	hSpCas9	negative selection	7010017
64807572	64807595	11	-	27260156	L33	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.1597138272716203	[743]	[731,314,651,789]	3	hSpCas9	negative selection	7010018
64805736	64805759	11	+	27260156	L33	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.5490453030368689	[496]	[648,288,451,835]	9	hSpCas9	negative selection	7010019
64807933	64807956	11	+	27260156	L33	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.05298183548680291	[689]	[741,264,455,747]	1	hSpCas9	negative selection	7074275
64807932	64807955	11	-	27260156	L33	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.19093612772084323	[286]	[329,76,158,232]	-4	hSpCas9	negative selection	7074276
64805755	64805778	11	-	27260156	L33	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.36329503841456057	[2308]	[1783,654,1139,1981]	-7	hSpCas9	negative selection	7074277
64807632	64807655	11	-	27260156	K562	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.5355566214165908	[93]	[20,119,19,67]	-6	hSpCas9	negative selection	7131268
64807572	64807595	11	-	27260156	K562	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.02655581876892099	[743]	[807,410,603,754]	0	hSpCas9	negative selection	7131269
64805736	64805759	11	+	27260156	K562	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.24355041158852564	[496]	[770,390,378,554]	3	hSpCas9	negative selection	7131270
64807933	64807956	11	+	27260156	K562	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.37120310990365146	[689]	[506,1063,890,703]	5	hSpCas9	negative selection	7195526
64807932	64807955	11	-	27260156	K562	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-1.0732757400191761	[286]	[151,86,148,98]	-8	hSpCas9	negative selection	7195527
64805755	64805778	11	-	27260156	K562	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.1702376450653591	[2308]	[2750,2280,2182,2061]	2	hSpCas9	negative selection	7195528
64807632	64807655	11	-	27260156	HT29	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.3188047510980998	[93]	[225,145,152,60]	6	hSpCas9	negative selection	7252519
64807572	64807595	11	-	27260156	HT29	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.2067079975432799	[743]	[814,798,853,677]	-4	hSpCas9	negative selection	7252520
64805736	64805759	11	+	27260156	HT29	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.17849784465393082	[496]	[470,534,597,523]	-4	hSpCas9	negative selection	7252521
64807933	64807956	11	+	27260156	HT29	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.2419582077235799	[689]	[1122,1213,789,876]	5	hSpCas9	negative selection	7316777
64807932	64807955	11	-	27260156	HT29	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.966240876461713	[286]	[160,120,221,199]	-8	hSpCas9	negative selection	7316778
64805755	64805778	11	-	27260156	HT29	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.15176327771186626	[2308]	[3171,3454,3185,2719]	3	hSpCas9	negative selection	7316779
64807632	64807655	11	-	27260156	MHHES1	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.0839384820521909	[93]	[48,174,152,36]	-1	hSpCas9	negative selection	7373770
64807572	64807595	11	-	27260156	MHHES1	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.13741067977050658	[743]	[749,897,944,509]	-3	hSpCas9	negative selection	7373771
64805736	64805759	11	+	27260156	MHHES1	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.32474716155846495	[496]	[794,615,650,722]	6	hSpCas9	negative selection	7373772
64807933	64807956	11	+	27260156	MHHES1	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.2621049382227516	[689]	[1033,971,912,827]	5	hSpCas9	negative selection	7438028
64807932	64807955	11	-	27260156	MHHES1	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-1.0295686616609618	[286]	[117,234,169,118]	-9	hSpCas9	negative selection	7438029
64805755	64805778	11	-	27260156	MHHES1	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.24776714553473722	[2308]	[1929,3055,2314,1604]	-5	hSpCas9	negative selection	7438030
64807632	64807655	11	-	27260156	MEWO	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.36551986126357416	[93]	[63,55,83]	-7	hSpCas9	negative selection	7495021
64807572	64807595	11	-	27260156	MEWO	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.0010407288935138093	[743]	[774,675,650]	0	hSpCas9	negative selection	7495022
64805736	64805759	11	+	27260156	MEWO	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.10866567553678971	[496]	[559,341,416]	-2	hSpCas9	negative selection	7495023
64807933	64807956	11	+	27260156	MEWO	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.051274947902604784	[689]	[735,572,710]	1	hSpCas9	negative selection	7559279
64807932	64807955	11	-	27260156	MEWO	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.8281082716639323	[286]	[146,123,181]	-9	hSpCas9	negative selection	7559280
64805755	64805778	11	-	27260156	MEWO	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.09403115566033193	[2308]	[2235,1891,1984]	-2	hSpCas9	negative selection	7559281
64807632	64807655	11	-	27260156	LNCAPCLONEFGC	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.26232425826771477	[93]	[79,40,92,74]	-4	hSpCas9	negative selection	7616272
64807572	64807595	11	-	27260156	LNCAPCLONEFGC	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.03334313083526608	[743]	[743,524,887,517]	0	hSpCas9	negative selection	7616273
64805736	64805759	11	+	27260156	LNCAPCLONEFGC	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.0065148502078670595	[496]	[500,266,667,415]	0	hSpCas9	negative selection	7616274
64807933	64807956	11	+	27260156	LNCAPCLONEFGC	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.40401985739529134	[689]	[840,722,811,935]	6	hSpCas9	negative selection	7680530
64807932	64807955	11	-	27260156	LNCAPCLONEFGC	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.40113031927928366	[286]	[128,245,166,238]	-6	hSpCas9	negative selection	7680531
64805755	64805778	11	-	27260156	LNCAPCLONEFGC	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.0817113248759127	[2308]	[1947,1857,3020,2173]	1	hSpCas9	negative selection	7680532
64807632	64807655	11	-	27260156	PANC0327	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.20792325234873843	[93]	[95,53,26,213]	3	hSpCas9	negative selection	7737523
64807572	64807595	11	-	27260156	PANC0327	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.3208569923946203	[743]	[974,762,750,832]	5	hSpCas9	negative selection	7737524
64805736	64805759	11	+	27260156	PANC0327	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.28515743240404734	[496]	[576,250,299,352]	-4	hSpCas9	negative selection	7737525
64807933	64807956	11	+	27260156	PANC0327	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.2844601189288656	[689]	[828,880,566,697]	4	hSpCas9	negative selection	7801781
64807932	64807955	11	-	27260156	PANC0327	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.005950604032056939	[286]	[450,166,279,144]	0	hSpCas9	negative selection	7801782
64805755	64805778	11	-	27260156	PANC0327	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.2768783628782683	[2308]	[2687,1813,3176,2364]	4	hSpCas9	negative selection	7801783
64807632	64807655	11	-	27260156	NCIH2009	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.7368643505524277	[93]	[73,41,119]	-7	hSpCas9	negative selection	7858774
64807572	64807595	11	-	27260156	NCIH2009	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.02996547123927984	[743]	[1117,912,1164]	0	hSpCas9	negative selection	7858775
64805736	64805759	11	+	27260156	NCIH2009	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.15803827757432154	[496]	[711,659,510]	-2	hSpCas9	negative selection	7858776
64807933	64807956	11	+	27260156	NCIH2009	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.4885775244264424	[689]	[1538,1151,1404]	6	hSpCas9	negative selection	7923032
64807932	64807955	11	-	27260156	NCIH2009	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.8226852849771109	[286]	[350,133,220]	-7	hSpCas9	negative selection	7923033
64805755	64805778	11	-	27260156	NCIH2009	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.46529363351887376	[2308]	[2366,2121,2526]	-6	hSpCas9	negative selection	7923034
64807632	64807655	11	-	27260156	NCIH1373	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.4840400214231144	[93]	[261,16,216,31]	5	hSpCas9	negative selection	7980025
64807572	64807595	11	-	27260156	NCIH1373	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.11081119607246093	[743]	[1143,656,697,170]	-1	hSpCas9	negative selection	7980026
64805736	64805759	11	+	27260156	NCIH1373	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.41476059307249336	[496]	[996,795,484,190]	4	hSpCas9	negative selection	7980027
64807933	64807956	11	+	27260156	NCIH1373	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.8008168597914586	[689]	[1751,1338,1357,255]	7	hSpCas9	negative selection	8044283
64807932	64807955	11	-	27260156	NCIH1373	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.7896381202462521	[286]	[259,171,166,40]	-7	hSpCas9	negative selection	8044284
64805755	64805778	11	-	27260156	NCIH1373	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.19916326927370953	[2308]	[4554,2073,2917,695]	2	hSpCas9	negative selection	8044285
64807632	64807655	11	-	27260156	PATU8902	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.33283614196863986	[93]	[129,252,221,21]	3	hSpCas9	negative selection	8101276
64807572	64807595	11	-	27260156	PATU8902	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.37320143056309135	[743]	[1026,555,615,1070]	-4	hSpCas9	negative selection	8101277
64805736	64805759	11	+	27260156	PATU8902	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.4721374799590333	[496]	[506,749,361,396]	-4	hSpCas9	negative selection	8101278
64807933	64807956	11	+	27260156	PATU8902	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.5254651102720423	[689]	[1474,1223,1339,1506]	5	hSpCas9	negative selection	8165534
64807932	64807955	11	-	27260156	PATU8902	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.7551187522191132	[286]	[270,99,236,349]	-6	hSpCas9	negative selection	8165535
64805755	64805778	11	-	27260156	PATU8902	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.21435939765002576	[2308]	[3229,2826,1841,3486]	-2	hSpCas9	negative selection	8165536
64807632	64807655	11	-	27260156	PANC1	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.20419794547827097	[93]	[60,54,80,77]	-3	hSpCas9	negative selection	8222527
64807572	64807595	11	-	27260156	PANC1	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.01407123352555073	[743]	[530,699,844,486]	0	hSpCas9	negative selection	8222528
64805736	64805759	11	+	27260156	PANC1	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.1151079695070619	[496]	[466,438,371,312]	-2	hSpCas9	negative selection	8222529
64807933	64807956	11	+	27260156	PANC1	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.3464050101048003	[689]	[686,715,913,689]	5	hSpCas9	negative selection	8286785
64807932	64807955	11	-	27260156	PANC1	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.8498939335077278	[286]	[129,129,89,184]	-8	hSpCas9	negative selection	8286786
64805755	64805778	11	-	27260156	PANC1	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.0992567409191385	[2308]	[1915,2889,1859,1979]	1	hSpCas9	negative selection	8286787
64807632	64807655	11	-	27260156	PANC0813	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.607458371877909	[93]	[133,304,63,165]	8	hSpCas9	negative selection	8343778
64807572	64807595	11	-	27260156	PANC0813	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.19798384810809022	[743]	[898,699,755,706]	-3	hSpCas9	negative selection	8343779
64805736	64805759	11	+	27260156	PANC0813	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.34975337501550036	[496]	[758,894,815,518]	5	hSpCas9	negative selection	8343780
64807933	64807956	11	+	27260156	PANC0813	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.14993542247515812	[689]	[936,873,1076,721]	2	hSpCas9	negative selection	8408036
64807932	64807955	11	-	27260156	PANC0813	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.48843792024440935	[286]	[156,246,318,230]	-6	hSpCas9	negative selection	8408037
64805755	64805778	11	-	27260156	PANC0813	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.18528544770746924	[2308]	[2728,2247,2661,1955]	-3	hSpCas9	negative selection	8408038
64807632	64807655	11	-	27260156	RDES	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.1024941640074788	[93]	[134,105,113,98]	1	hSpCas9	negative selection	8465029
64807572	64807595	11	-	27260156	RDES	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.39388523746735193	[743]	[909,1104,1221,1304]	6	hSpCas9	negative selection	8465030
64805736	64805759	11	+	27260156	RDES	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.5498543469007923	[496]	[700,833,733,1120]	8	hSpCas9	negative selection	8465031
64807933	64807956	11	+	27260156	RDES	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.5112692785504117	[689]	[753,1083,1167,1654]	7	hSpCas9	negative selection	8529287
64807932	64807955	11	-	27260156	RDES	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	0.14306654784635142	[286]	[198,362,538,394]	2	hSpCas9	negative selection	8529288
64805755	64805778	11	-	27260156	RDES	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.3163930112029618	[2308]	[2581,3272,3686,3840]	5	hSpCas9	negative selection	8529289
64807632	64807655	11	-	27260156	PC3	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.136311384028021	[93]	[27,60,190,125]	-3	hSpCas9	negative selection	8586280
64807572	64807595	11	-	27260156	PC3	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.08500485961179749	[743]	[462,876,1258,794]	2	hSpCas9	negative selection	8586281
64805736	64805759	11	+	27260156	PC3	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.2082209001875076	[496]	[340,581,835,684]	4	hSpCas9	negative selection	8586282
64807933	64807956	11	+	27260156	PC3	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.006848816705490313	[689]	[367,693,1293,727]	0	hSpCas9	negative selection	8650538
64807932	64807955	11	-	27260156	PC3	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	0.07610284196291683	[286]	[192,264,547,316]	1	hSpCas9	negative selection	8650539
64805755	64805778	11	-	27260156	PC3	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.030054722941190715	[2308]	[1427,2413,4148,2283]	0	hSpCas9	negative selection	8650540
64807632	64807655	11	-	27260156	PATU8988T	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.3772522206062636	[93]	[47,135,139,151]	6	hSpCas9	negative selection	8707531
64807572	64807595	11	-	27260156	PATU8988T	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.27934786060330097	[743]	[579,838,949,1137]	5	hSpCas9	negative selection	8707532
64805736	64805759	11	+	27260156	PATU8988T	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.2493680253276364	[496]	[604,616,502,562]	4	hSpCas9	negative selection	8707533
64807933	64807956	11	+	27260156	PATU8988T	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.5796093286608496	[689]	[1094,1008,996,875]	8	hSpCas9	negative selection	8771789
64807932	64807955	11	-	27260156	PATU8988T	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.12008475227306481	[286]	[172,368,298,183]	-2	hSpCas9	negative selection	8771790
64805755	64805778	11	-	27260156	PATU8988T	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.23571546224043205	[2308]	[2467,2700,2521,2842]	4	hSpCas9	negative selection	8771791
64807632	64807655	11	-	27260156	T47D	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.23598840634458096	[93]	[114,97,85,71]	-5	hSpCas9	negative selection	8828782
64807572	64807595	11	-	27260156	T47D	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.045226485232782276	[743]	[847,861,881,990]	0	hSpCas9	negative selection	8828783
64805736	64805759	11	+	27260156	T47D	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.09085175593285928	[496]	[677,530,658,604]	2	hSpCas9	negative selection	8828784
64807933	64807956	11	+	27260156	T47D	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.25376024608051884	[689]	[1046,974,872,937]	5	hSpCas9	negative selection	8893040
64807932	64807955	11	-	27260156	T47D	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.43684321203793086	[286]	[287,241,233,223]	-7	hSpCas9	negative selection	8893041
64805755	64805778	11	-	27260156	T47D	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	0.13004710719363466	[2308]	[2850,2816,3084,3031]	2	hSpCas9	negative selection	8893042
64807632	64807655	11	-	27260156	SU8686	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.2871750345182833	[93]	[65,152,81,159]	5	hSpCas9	negative selection	8950033
64807572	64807595	11	-	27260156	SU8686	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	0.31996703476918587	[743]	[953,977,763,972]	5	hSpCas9	negative selection	8950034
64805736	64805759	11	+	27260156	SU8686	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.6365280671048625	[496]	[758,739,756,813]	9	hSpCas9	negative selection	8950035
64807933	64807956	11	+	27260156	SU8686	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.2310752802766396	[689]	[697,645,871,1066]	4	hSpCas9	negative selection	9014291
64807932	64807955	11	-	27260156	SU8686	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.11240917471968992	[286]	[224,296,320,198]	-2	hSpCas9	negative selection	9014292
64805755	64805778	11	-	27260156	SU8686	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.2905289183134063	[2308]	[1748,1532,2113,2193]	-5	hSpCas9	negative selection	9014293
64807632	64807655	11	-	27260156	SKES1	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.6107566056673353	[93]	[80,58,39,66]	-8	hSpCas9	negative selection	9071284
64807572	64807595	11	-	27260156	SKES1	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.008575970754676754	[743]	[688,924,632,715]	0	hSpCas9	negative selection	9071285
64805736	64805759	11	+	27260156	SKES1	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.14027417009699605	[496]	[626,458,574,521]	3	hSpCas9	negative selection	9071286
64807933	64807956	11	+	27260156	SKES1	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.14745912482595047	[689]	[830,896,739,616]	3	hSpCas9	negative selection	9135542
64807932	64807955	11	-	27260156	SKES1	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.44734516196447194	[286]	[207,236,217,180]	-7	hSpCas9	negative selection	9135543
64805755	64805778	11	-	27260156	SKES1	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.009951953188397145	[2308]	[2339,2468,2272,2095]	0	hSpCas9	negative selection	9135544
64807632	64807655	11	-	27260156	TOV112D	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.05832343608917778	[93]	[46,207,107,52]	1	hSpCas9	negative selection	9192535
64807572	64807595	11	-	27260156	TOV112D	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.2099045168564172	[743]	[811,867,641,331]	-4	hSpCas9	negative selection	9192536
64805736	64805759	11	+	27260156	TOV112D	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.08130612745747103	[496]	[744,615,329,456]	1	hSpCas9	negative selection	9192537
64807933	64807956	11	+	27260156	TOV112D	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.15138618113457492	[689]	[706,1145,576,727]	3	hSpCas9	negative selection	9256793
64807932	64807955	11	-	27260156	TOV112D	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.5302406800749413	[286]	[315,163,79,235]	-8	hSpCas9	negative selection	9256794
64805755	64805778	11	-	27260156	TOV112D	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.09041768348820556	[2308]	[2045,2616,2432,1700]	-2	hSpCas9	negative selection	9256795
64807632	64807655	11	-	27260156	TC71	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.5777466412493819	[93]	[55,56,84,71]	-9	hSpCas9	negative selection	9313786
64807572	64807595	11	-	27260156	TC71	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.08113768342332894	[743]	[724,757,702,836]	-2	hSpCas9	negative selection	9313787
64805736	64805759	11	+	27260156	TC71	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	0.11396753939222586	[496]	[478,539,588,707]	3	hSpCas9	negative selection	9313788
64807933	64807956	11	+	27260156	TC71	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.25849250751719144	[689]	[964,800,917,849]	6	hSpCas9	negative selection	9378044
64807932	64807955	11	-	27260156	TC71	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.13865742751393906	[286]	[218,264,270,369]	-4	hSpCas9	negative selection	9378045
64805755	64805778	11	-	27260156	TC71	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.0798459304289536	[2308]	[2212,2434,2108,2638]	-2	hSpCas9	negative selection	9378046
64807632	64807655	11	-	27260156	TC32	viability	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.0888019563487239	[93]	[77,58,121,84]	-1	hSpCas9	negative selection	9435037
64807572	64807595	11	-	27260156	TC32	viability	TGACCTGCACACCGACTCGCTGG	MEN1	ENSG00000133895	-0.11791518779909993	[743]	[740,537,804,498]	-2	hSpCas9	negative selection	9435038
64805736	64805759	11	+	27260156	TC32	viability	TGTAGATCTCCTCGTCTTCCCGG	MEN1	ENSG00000133895	-0.027081214343150938	[496]	[547,275,521,532]	0	hSpCas9	negative selection	9435039
64807933	64807956	11	+	27260156	TC32	viability	CTCGTTGCCCTTGCCGTGCCAGG	MEN1	ENSG00000133895	0.38726681738557256	[689]	[970,570,1004,913]	6	hSpCas9	negative selection	9499295
64807932	64807955	11	-	27260156	TC32	viability	CTGGCACGGCAAGGGCAACGAGG	MEN1	ENSG00000133895	-0.3293060447381153	[286]	[215,134,254,280]	-6	hSpCas9	negative selection	9499296
64805755	64805778	11	-	27260156	TC32	viability	CTCACAGCTACAACTACTGCCGG	MEN1	ENSG00000133895	-0.010057515597070132	[2308]	[1747,1703,2804,2594]	0	hSpCas9	negative selection	9499297
64805745	64805768	11	-	27869803	HPAFII	viability after 27 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-1.3983103133134707	[231]	[78,18,NaN]	-7	hSpCas9	negative selection	9542968
64806278	64806301	11	+	27869803	HPAFII	viability after 27 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-0.873770734336422	[326]	[119,71,NaN]	-6	hSpCas9	negative selection	9542969
64807025	64807048	11	+	27869803	HPAFII	viability after 27 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-1.4836149786087462	[249]	[70,26,NaN]	-7	hSpCas9	negative selection	9542970
64807632	64807655	11	-	27869803	HPAFII	viability after 27 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.13143922874291086	[346]	[159,171,NaN]	-1	hSpCas9	negative selection	9542971
64807890	64807913	11	-	27869803	HPAFII	viability after 27 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.8955700594730824	[115]	[155,77,NaN]	7	hSpCas9	negative selection	9542972
64809782	64809805	11	+	27869803	HPAFII	viability after 27 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.7235764493511003	[447]	[122,158,NaN]	-5	hSpCas9	negative selection	9542973
64805745	64805768	11	-	27869803	HPAFII	viability after 15 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-0.44960218000004026	[231]	[279,121,NaN]	-5	hSpCas9	negative selection	9625417
64806278	64806301	11	+	27869803	HPAFII	viability after 15 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-0.038776779208578915	[326]	[515,233,NaN]	0	hSpCas9	negative selection	9625418
64807025	64807048	11	+	27869803	HPAFII	viability after 15 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-0.16396230403855896	[249]	[253,230,NaN]	-2	hSpCas9	negative selection	9625419
64807632	64807655	11	-	27869803	HPAFII	viability after 15 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.19157715773801093	[346]	[394,283,NaN]	-2	hSpCas9	negative selection	9625420
64807890	64807913	11	-	27869803	HPAFII	viability after 15 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.890731376183773	[115]	[232,229,NaN]	8	hSpCas9	negative selection	9625421
64809782	64809805	11	+	27869803	HPAFII	viability after 15 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.5327088281759382	[447]	[420,277,NaN]	-5	hSpCas9	negative selection	9625422
64805745	64805768	11	-	27869803	ASPC1	viability after 36 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	1.0021557053430514	[874]	[623,899,367]	8	hSpCas9	negative selection	9707866
64806278	64806301	11	+	27869803	ASPC1	viability after 36 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	0.6212333306790448	[931]	[653,699,228]	6	hSpCas9	negative selection	9707867
64807025	64807048	11	+	27869803	ASPC1	viability after 36 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-0.335740799324411	[790]	[357,176,151]	-3	hSpCas9	negative selection	9707868
64807632	64807655	11	-	27869803	ASPC1	viability after 36 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	0.7179343819834426	[634]	[609,319,223]	7	hSpCas9	negative selection	9707869
64807890	64807913	11	-	27869803	ASPC1	viability after 36 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.8580895566940211	[411]	[454,132,222]	8	hSpCas9	negative selection	9707870
64809782	64809805	11	+	27869803	ASPC1	viability after 36 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	1.1942033247046346	[831]	[549,1025,450]	9	hSpCas9	negative selection	9707871
64805745	64805768	11	-	27869803	PATU8988S	viability after 35 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	0.8476385914494504	[820]	[391,798,NaN]	8	hSpCas9	negative selection	9790315
64806278	64806301	11	+	27869803	PATU8988S	viability after 35 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	0.9464508132332407	[899]	[713,682,NaN]	8	hSpCas9	negative selection	9790316
64807025	64807048	11	+	27869803	PATU8988S	viability after 35 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-0.028126447510114193	[573]	[320,131,NaN]	0	hSpCas9	negative selection	9790317
64807632	64807655	11	-	27869803	PATU8988S	viability after 35 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.19815213830295586	[546]	[205,177,NaN]	-2	hSpCas9	negative selection	9790318
64807890	64807913	11	-	27869803	PATU8988S	viability after 35 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.939331078477685	[322]	[232,265,NaN]	8	hSpCas9	negative selection	9790319
64809782	64809805	11	+	27869803	PATU8988S	viability after 35 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	1.0326806596855023	[690]	[504,633,NaN]	9	hSpCas9	negative selection	9790320
64805745	64805768	11	-	27869803	PATU8988S	viability after 31 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	0.2846535787328639	[820]	[268,563,NaN]	3	hSpCas9	negative selection	9872764
64806278	64806301	11	+	27869803	PATU8988S	viability after 31 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	0.9432191497841319	[899]	[488,945,NaN]	9	hSpCas9	negative selection	9872765
64807025	64807048	11	+	27869803	PATU8988S	viability after 31 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	0.17212801404882005	[573]	[267,244,NaN]	2	hSpCas9	negative selection	9872766
64807632	64807655	11	-	27869803	PATU8988S	viability after 31 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.16017421945608654	[546]	[159,239,NaN]	-2	hSpCas9	negative selection	9872767
64807890	64807913	11	-	27869803	PATU8988S	viability after 31 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.42572397419561664	[322]	[183,158,NaN]	5	hSpCas9	negative selection	9872768
64809782	64809805	11	+	27869803	PATU8988S	viability after 31 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	0.8216831005352062	[690]	[453,528,NaN]	8	hSpCas9	negative selection	9872769
64805745	64805768	11	-	27869803	HPAFII	viability after 35 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-1.645326089348749	[231]	[69,0,NaN]	-7	hSpCas9	negative selection	9955213
64806278	64806301	11	+	27869803	HPAFII	viability after 35 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-0.8853005432145997	[326]	[35,149,NaN]	-5	hSpCas9	negative selection	9955214
64807025	64807048	11	+	27869803	HPAFII	viability after 35 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-1.6914377628893955	[249]	[57,17,NaN]	-7	hSpCas9	negative selection	9955215
64807632	64807655	11	-	27869803	HPAFII	viability after 35 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.05403665919161388	[346]	[116,227,NaN]	0	hSpCas9	negative selection	9955216
64807890	64807913	11	-	27869803	HPAFII	viability after 35 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.9338534488239626	[115]	[130,90,NaN]	6	hSpCas9	negative selection	9955217
64809782	64809805	11	+	27869803	HPAFII	viability after 35 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.7099810704806299	[447]	[140,135,NaN]	-4	hSpCas9	negative selection	9955218
64805745	64805768	11	-	27869803	HPAFII	viability after 31 days	CAACTACTGCCGGGAAGACGAGG	MEN1	ENSG00000133895	-1.357650364194117	[231]	[79,18,NaN]	-7	hSpCas9	negative selection	10037662
64806278	64806301	11	+	27869803	HPAFII	viability after 31 days	GCACATTGCGGTTGCGACAGTGG	MEN1	ENSG00000133895	-0.794969462897217	[326]	[122,86,NaN]	-5	hSpCas9	negative selection	10037663
64807025	64807048	11	+	27869803	HPAFII	viability after 31 days	TGAGTGGGTCTGGCCGGCCAGGG	MEN1	ENSG00000133895	-0.5416656554328227	[249]	[104,86,NaN]	-4	hSpCas9	negative selection	10037664
64807632	64807655	11	-	27869803	HPAFII	viability after 31 days	CATGCGCTGTGACCGCAAGATGG	MEN1	ENSG00000133895	-0.29007697564528123	[346]	[142,176,NaN]	-2	hSpCas9	negative selection	10037665
64807890	64807913	11	-	27869803	HPAFII	viability after 31 days	CAATGCCGGTGTGGCTGAGCGGG	MEN1	ENSG00000133895	0.27092957495451964	[115]	[101,52,NaN]	2	hSpCas9	negative selection	10037666
64809782	64809805	11	+	27869803	HPAFII	viability after 31 days	CTTCTCGAGGATAGAGGGACAGG	MEN1	ENSG00000133895	-0.7366030183830414	[447]	[114,189,NaN]	-5	hSpCas9	negative selection	10037667
64809852	64809875	11	+	28162770	P31FUJ	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	-0.2872499884367549	[323]	[311]	-3	hSpCas9	negative selection	10191024
64809699	64809722	11	-	28162770	P31FUJ	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-0.13290363436025787	[529]	[567]	-1	hSpCas9	negative selection	10191025
64808050	64808073	11	+	28162770	P31FUJ	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	-0.8076048389153131	[282]	[189]	-6	hSpCas9	negative selection	10191026
64807978	64808001	11	+	28162770	P31FUJ	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	-0.375341318061612	[286]	[259]	-3	hSpCas9	negative selection	10191027
64807042	64807065	11	-	28162770	P31FUJ	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-1.5189591682799188	[238]	[97]	-7	hSpCas9	negative selection	10191028
64805667	64805690	11	-	28162770	P31FUJ	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	-1.7353025449435617	[33]	[11]	-8	hSpCas9	negative selection	10191029
64805157	64805180	11	+	28162770	P31FUJ	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	-0.05771549785628727	[92]	[104]	0	hSpCas9	negative selection	10191030
64809935	64809958	11	+	28162770	P31FUJ	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-0.642786475966937	[189]	[142]	-5	hSpCas9	negative selection	10191031
64809877	64809900	11	+	28162770	P31FUJ	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	0.6882969678387059	[356]	[675]	7	hSpCas9	negative selection	10191032
64809828	64809851	11	+	28162770	P31FUJ	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-0.5376567859427994	[20]	[16]	-4	hSpCas9	negative selection	10191033
64809852	64809875	11	+	28162770	TF1	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	NaN	[NaN]	[233]	1	hSpCas9	negative selection	10360390
64809699	64809722	11	-	28162770	TF1	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	NaN	[NaN]	[332]	1	hSpCas9	negative selection	10360391
64808050	64808073	11	+	28162770	TF1	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10360392
64807978	64808001	11	+	28162770	TF1	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	NaN	[NaN]	[285]	1	hSpCas9	negative selection	10360393
64807042	64807065	11	-	28162770	TF1	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10360394
64805667	64805690	11	-	28162770	TF1	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10360395
64805157	64805180	11	+	28162770	TF1	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10360396
64809935	64809958	11	+	28162770	TF1	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10360397
64809877	64809900	11	+	28162770	TF1	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	NaN	[NaN]	[249]	1	hSpCas9	negative selection	10360398
64809828	64809851	11	+	28162770	TF1	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10360399
64809852	64809875	11	+	28162770	SKM1	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	0.3971668224401561	[127]	[297]	4	hSpCas9	negative selection	10529756
64809699	64809722	11	-	28162770	SKM1	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-0.5875364443849824	[118]	[139]	-5	hSpCas9	negative selection	10529757
64808050	64808073	11	+	28162770	SKM1	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	0.13993026114447504	[95]	[186]	1	hSpCas9	negative selection	10529758
64807978	64808001	11	+	28162770	SKM1	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	0.2775339755289089	[83]	[179]	2	hSpCas9	negative selection	10529759
64807042	64807065	11	-	28162770	SKM1	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-2.2713090993855953	[70]	[25]	-8	hSpCas9	negative selection	10529760
64805667	64805690	11	-	28162770	SKM1	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	-0.5996092766855576	[5]	[6]	-5	hSpCas9	negative selection	10529761
64805157	64805180	11	+	28162770	SKM1	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	-0.45276788835628623	[23]	[30]	-4	hSpCas9	negative selection	10529762
64809935	64809958	11	+	28162770	SKM1	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-1.0349954213562038	[50]	[43]	-6	hSpCas9	negative selection	10529763
64809877	64809900	11	+	28162770	SKM1	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	0.923068945781256	[70]	[237]	8	hSpCas9	negative selection	10529764
64809828	64809851	11	+	28162770	SKM1	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-0.3074285251922473	[6]	[9]	-3	hSpCas9	negative selection	10529765
64809852	64809875	11	+	28162770	SKM1	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	0.3971668224401561	[127]	[297]	4	hSpCas9	negative selection	10699122
64809699	64809722	11	-	28162770	SKM1	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-0.5875364443849824	[118]	[139]	-5	hSpCas9	negative selection	10699123
64808050	64808073	11	+	28162770	SKM1	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	0.13993026114447504	[95]	[186]	1	hSpCas9	negative selection	10699124
64807978	64808001	11	+	28162770	SKM1	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	0.2775339755289089	[83]	[179]	2	hSpCas9	negative selection	10699125
64807042	64807065	11	-	28162770	SKM1	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-2.2713090993855953	[70]	[25]	-8	hSpCas9	negative selection	10699126
64805667	64805690	11	-	28162770	SKM1	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	-0.5996092766855576	[5]	[6]	-5	hSpCas9	negative selection	10699127
64805157	64805180	11	+	28162770	SKM1	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	-0.45276788835628623	[23]	[30]	-4	hSpCas9	negative selection	10699128
64809935	64809958	11	+	28162770	SKM1	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-1.0349954213562038	[50]	[43]	-6	hSpCas9	negative selection	10699129
64809877	64809900	11	+	28162770	SKM1	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	0.923068945781256	[70]	[237]	8	hSpCas9	negative selection	10699130
64809828	64809851	11	+	28162770	SKM1	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-0.3074285251922473	[6]	[9]	-3	hSpCas9	negative selection	10699131
64809852	64809875	11	+	28162770	PL21	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	1.1858199431722534	[404]	[400]	8	hSpCas9	negative selection	10868488
64809699	64809722	11	-	28162770	PL21	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	0.5623118736479067	[402]	[258]	5	hSpCas9	negative selection	10868489
64808050	64808073	11	+	28162770	PL21	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	0.11607534970084576	[264]	[124]	1	hSpCas9	negative selection	10868490
64807978	64808001	11	+	28162770	PL21	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	0.41867456015625426	[427]	[248]	3	hSpCas9	negative selection	10868491
64807042	64807065	11	-	28162770	PL21	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-1.3994696621962373	[296]	[48]	-7	hSpCas9	negative selection	10868492
64805667	64805690	11	-	28162770	PL21	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	0.6382607268812053	[30]	[20]	5	hSpCas9	negative selection	10868493
64805157	64805180	11	+	28162770	PL21	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	0.46317402032311383	[104]	[62]	4	hSpCas9	negative selection	10868494
64809935	64809958	11	+	28162770	PL21	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	1.1723946240064158	[104]	[102]	8	hSpCas9	negative selection	10868495
64809877	64809900	11	+	28162770	PL21	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	0.5069242231161406	[248]	[153]	4	hSpCas9	negative selection	10868496
64809828	64809851	11	+	28162770	PL21	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-2.7067509811191988	[14]	[0]	-9	hSpCas9	negative selection	10868497
64809852	64809875	11	+	28162770	P31FUJ	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	-0.2872499884367549	[323]	[311]	-3	hSpCas9	negative selection	11037854
64809699	64809722	11	-	28162770	P31FUJ	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-0.13290363436025787	[529]	[567]	-1	hSpCas9	negative selection	11037855
64808050	64808073	11	+	28162770	P31FUJ	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	-0.8076048389153131	[282]	[189]	-6	hSpCas9	negative selection	11037856
64807978	64808001	11	+	28162770	P31FUJ	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	-0.375341318061612	[286]	[259]	-3	hSpCas9	negative selection	11037857
64807042	64807065	11	-	28162770	P31FUJ	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-1.5189591682799188	[238]	[97]	-7	hSpCas9	negative selection	11037858
64805667	64805690	11	-	28162770	P31FUJ	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	-1.7353025449435617	[33]	[11]	-8	hSpCas9	negative selection	11037859
64805157	64805180	11	+	28162770	P31FUJ	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	-0.05771549785628727	[92]	[104]	0	hSpCas9	negative selection	11037860
64809935	64809958	11	+	28162770	P31FUJ	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-0.642786475966937	[189]	[142]	-5	hSpCas9	negative selection	11037861
64809877	64809900	11	+	28162770	P31FUJ	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	0.6882969678387059	[356]	[675]	7	hSpCas9	negative selection	11037862
64809828	64809851	11	+	28162770	P31FUJ	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-0.5376567859427994	[20]	[16]	-4	hSpCas9	negative selection	11037863
64809852	64809875	11	+	28162770	OCIAML5	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	1.156633124086388	[123]	[498]	8	hSpCas9	negative selection	11207220
64809699	64809722	11	-	28162770	OCIAML5	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-0.6080622189002827	[406]	[481]	-4	hSpCas9	negative selection	11207221
64808050	64808073	11	+	28162770	OCIAML5	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	0.4753997075647953	[103]	[260]	4	hSpCas9	negative selection	11207222
64807978	64808001	11	+	28162770	OCIAML5	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	0.5072149385057351	[121]	[312]	4	hSpCas9	negative selection	11207223
64807042	64807065	11	-	28162770	OCIAML5	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-2.2608721164313264	[153]	[57]	-8	hSpCas9	negative selection	11207224
64805667	64805690	11	-	28162770	OCIAML5	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	-1.5682736048634056	[22]	[13]	-7	hSpCas9	negative selection	11207225
64805157	64805180	11	+	28162770	OCIAML5	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	0.3262706703945154	[56]	[128]	2	hSpCas9	negative selection	11207226
64809935	64809958	11	+	28162770	OCIAML5	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	0.7716283243458737	[97]	[301]	6	hSpCas9	negative selection	11207227
64809877	64809900	11	+	28162770	OCIAML5	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	1.2841991192270843	[158]	[698]	9	hSpCas9	negative selection	11207228
64809828	64809851	11	+	28162770	OCIAML5	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	1.1734685212431402	[13]	[56]	8	hSpCas9	negative selection	11207229
64809852	64809875	11	+	28162770	EOL1	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	0.0818913604244893	[754]	[420]	0	hSpCas9	negative selection	11376586
64809699	64809722	11	-	28162770	EOL1	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-1.9443124166001677	[598]	[81]	-8	hSpCas9	negative selection	11376587
64808050	64808073	11	+	28162770	EOL1	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	-1.2232058488731576	[451]	[101]	-7	hSpCas9	negative selection	11376588
64807978	64808001	11	+	28162770	EOL1	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	-1.3244488008629767	[674]	[141]	-7	hSpCas9	negative selection	11376589
64807042	64807065	11	-	28162770	EOL1	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-2.3999542669806546	[560]	[55]	-8	hSpCas9	negative selection	11376590
64805667	64805690	11	-	28162770	EOL1	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	0.31311305948818724	[54]	[35]	3	hSpCas9	negative selection	11376591
64805157	64805180	11	+	28162770	EOL1	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	0.4249767620800229	[81]	[57]	4	hSpCas9	negative selection	11376592
64809935	64809958	11	+	28162770	EOL1	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	0.02838358255507445	[200]	[107]	0	hSpCas9	negative selection	11376593
64809877	64809900	11	+	28162770	EOL1	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	0.7889601777713594	[300]	[273]	7	hSpCas9	negative selection	11376594
64809828	64809851	11	+	28162770	EOL1	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	1.8756381710895882	[14]	[28]	9	hSpCas9	negative selection	11376595
64809852	64809875	11	+	28162770	MOLM13	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	-1.299133446477807	[581]	[170]	-6	hSpCas9	negative selection	11545952
64809699	64809722	11	-	28162770	MOLM13	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-3.4599608326995854	[623]	[40]	-8	hSpCas9	negative selection	11545953
64808050	64808073	11	+	28162770	MOLM13	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	-0.40657973637156214	[351]	[191]	-2	hSpCas9	negative selection	11545954
64807978	64808001	11	+	28162770	MOLM13	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	-3.8201527191903732	[546]	[27]	-9	hSpCas9	negative selection	11545955
64807042	64807065	11	-	28162770	MOLM13	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-1.98305577120489	[338]	[61]	-7	hSpCas9	negative selection	11545956
64805667	64805690	11	-	28162770	MOLM13	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	-1.4390012140639392	[44]	[11]	-6	hSpCas9	negative selection	11545957
64805157	64805180	11	+	28162770	MOLM13	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	-1.0575721074279156	[94]	[32]	-5	hSpCas9	negative selection	11545958
64809935	64809958	11	+	28162770	MOLM13	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-4.854038713342783	[199]	[4]	-9	hSpCas9	negative selection	11545959
64809877	64809900	11	+	28162770	MOLM13	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	-1.0740043972846913	[296]	[101]	-5	hSpCas9	negative selection	11545960
64809828	64809851	11	+	28162770	MOLM13	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-3.9915422370927187	[21]	[0]	-9	hSpCas9	negative selection	11545961
64809852	64809875	11	+	28162770	HEL	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	0.9464826868521146	[494]	[610]	8	hSpCas9	negative selection	11715318
64809699	64809722	11	-	28162770	HEL	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-1.818016967584322	[544]	[98]	-7	hSpCas9	negative selection	11715319
64808050	64808073	11	+	28162770	HEL	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	-0.9059601247340278	[274]	[93]	-5	hSpCas9	negative selection	11715320
64807978	64808001	11	+	28162770	HEL	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	-0.9790035179955594	[436]	[141]	-6	hSpCas9	negative selection	11715321
64807042	64807065	11	-	28162770	HEL	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-2.0318608812054757	[331]	[51]	-8	hSpCas9	negative selection	11715322
64805667	64805690	11	-	28162770	HEL	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	-2.3207352919745285	[38]	[4]	-8	hSpCas9	negative selection	11715323
64805157	64805180	11	+	28162770	HEL	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	-1.8897562488266635	[80]	[13]	-7	hSpCas9	negative selection	11715324
64809935	64809958	11	+	28162770	HEL	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-1.5588950291692938	[183]	[39]	-7	hSpCas9	negative selection	11715325
64809877	64809900	11	+	28162770	HEL	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	0.8607017286999482	[232]	[270]	7	hSpCas9	negative selection	11715326
64809828	64809851	11	+	28162770	HEL	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-0.7357727912533729	[25]	[9]	-5	hSpCas9	negative selection	11715327
64809852	64809875	11	+	28162770	MV411	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	-0.09187262233282356	[333]	[263]	0	hSpCas9	negative selection	11884684
64809699	64809722	11	-	28162770	MV411	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-2.5740615535950986	[409]	[57]	-9	hSpCas9	negative selection	11884685
64808050	64808073	11	+	28162770	MV411	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	-3.1238182564681556	[237]	[22]	-9	hSpCas9	negative selection	11884686
64807978	64808001	11	+	28162770	MV411	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	-2.321670998737544	[361]	[60]	-8	hSpCas9	negative selection	11884687
64807042	64807065	11	-	28162770	MV411	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-2.1743891141587075	[283]	[52]	-8	hSpCas9	negative selection	11884688
64805667	64805690	11	-	28162770	MV411	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	0.47691939690554275	[28]	[33]	4	hSpCas9	negative selection	11884689
64805157	64805180	11	+	28162770	MV411	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	0.11208569788788902	[66]	[60]	1	hSpCas9	negative selection	11884690
64809935	64809958	11	+	28162770	MV411	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-3.659453044825743	[119]	[7]	-9	hSpCas9	negative selection	11884691
64809877	64809900	11	+	28162770	MV411	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	0.19706402826765598	[203]	[196]	1	hSpCas9	negative selection	11884692
64809828	64809851	11	+	28162770	MV411	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-3.4530021673583167	[12]	[0]	-9	hSpCas9	negative selection	11884693
64809852	64809875	11	+	28162770	MONOMAC1	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	-1.3345403708094887	[274]	[124]	-7	hSpCas9	negative selection	12054050
64809699	64809722	11	-	28162770	MONOMAC1	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-2.551879564419651	[265]	[51]	-9	hSpCas9	negative selection	12054051
64808050	64808073	11	+	28162770	MONOMAC1	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	-1.606681087568179	[177]	[66]	-8	hSpCas9	negative selection	12054052
64807978	64808001	11	+	28162770	MONOMAC1	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	-1.6236623206136096	[249]	[92]	-8	hSpCas9	negative selection	12054053
64807042	64807065	11	-	28162770	MONOMAC1	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-1.603853839533429	[174]	[65]	-8	hSpCas9	negative selection	12054054
64805667	64805690	11	-	28162770	MONOMAC1	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	-0.9746444257231053	[11]	[6]	-6	hSpCas9	negative selection	12054055
64805157	64805180	11	+	28162770	MONOMAC1	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	-0.45337660031933935	[42]	[35]	-4	hSpCas9	negative selection	12054056
64809935	64809958	11	+	28162770	MONOMAC1	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-2.7413573632833637	[104]	[17]	-9	hSpCas9	negative selection	12054057
64809877	64809900	11	+	28162770	MONOMAC1	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	-0.7465940116495109	[160]	[109]	-6	hSpCas9	negative selection	12054058
64809828	64809851	11	+	28162770	MONOMAC1	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-3.197036847059554	[7]	[0]	-9	hSpCas9	negative selection	12054059
64809852	64809875	11	+	28162770	OCIAML2	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	-0.5091039730567969	[75]	[295]	-4	hSpCas9	negative selection	12223416
64809699	64809722	11	-	28162770	OCIAML2	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-1.84677831112741	[60]	[93]	-8	hSpCas9	negative selection	12223417
64808050	64808073	11	+	28162770	OCIAML2	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	-1.8476994743219846	[49]	[76]	-8	hSpCas9	negative selection	12223418
64807978	64808001	11	+	28162770	OCIAML2	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	-2.264178947774735	[64]	[74]	-8	hSpCas9	negative selection	12223419
64807042	64807065	11	-	28162770	OCIAML2	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-1.9815917445195406	[56]	[79]	-8	hSpCas9	negative selection	12223420
64805667	64805690	11	-	28162770	OCIAML2	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	-5.4706298252421615	[7]	[0]	-9	hSpCas9	negative selection	12223421
64805157	64805180	11	+	28162770	OCIAML2	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	-0.9142364767177762	[16]	[49]	-6	hSpCas9	negative selection	12223422
64809935	64809958	11	+	28162770	OCIAML2	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-2.684754630595009	[28]	[24]	-9	hSpCas9	negative selection	12223423
64809877	64809900	11	+	28162770	OCIAML2	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	0.13140618883793648	[41]	[254]	1	hSpCas9	negative selection	12223424
64809828	64809851	11	+	28162770	OCIAML2	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-3.4706298252421615	[1]	[0]	-9	hSpCas9	negative selection	12223425
64809852	64809875	11	+	28162770	OCIAML3	viability	GATGATAGACAGGTCGGCCACGG	MEN1	ENSG00000133895	-1.3621919651010894	[108]	[127]	-7	hSpCas9	negative selection	12392782
64809699	64809722	11	-	28162770	OCIAML3	viability	GCCGCTCCTACTTCAAGGATCGG	MEN1	ENSG00000133895	-4.1245223570229435	[103]	[17]	-9	hSpCas9	negative selection	12392783
64808050	64808073	11	+	28162770	OCIAML3	viability	GCAGGCCCCAACCACAGCAAAGG	MEN1	ENSG00000133895	-1.9029578812133154	[82]	[66]	-8	hSpCas9	negative selection	12392784
64807978	64808001	11	+	28162770	OCIAML3	viability	ATTGGGCCCAAACACTACCCAGG	MEN1	ENSG00000133895	-1.612866667575479	[76]	[75]	-8	hSpCas9	negative selection	12392785
64807042	64807065	11	-	28162770	OCIAML3	viability	GAGGAGCTGGAGCCCACCCCTGG	MEN1	ENSG00000133895	-1.8715416158530722	[79]	[65]	-8	hSpCas9	negative selection	12392786
64805667	64805690	11	-	28162770	OCIAML3	viability	GGAGGCAGCCAGCTTGCTGGAGG	MEN1	ENSG00000133895	-2.1789701410453195	[8]	[5]	-8	hSpCas9	negative selection	12392787
64805157	64805180	11	+	28162770	OCIAML3	viability	GCACTCAGGGTCCTGGAGGGCGG	MEN1	ENSG00000133895	-1.1789701410453193	[17]	[23]	-7	hSpCas9	negative selection	12392788
64809935	64809958	11	+	28162770	OCIAML3	viability	GAACGTTGGTAGGGATGACGCGG	MEN1	ENSG00000133895	-1.9081162307522264	[45]	[36]	-8	hSpCas9	negative selection	12392789
64809877	64809900	11	+	28162770	OCIAML3	viability	AAGTAGGTGAGGCCGCCAGGCGG	MEN1	ENSG00000133895	-1.1841318461610981	[69]	[92]	-7	hSpCas9	negative selection	12392790
64809828	64809851	11	+	28162770	OCIAML3	viability	GGTGAAGCGGGCATAGAGGGCGG	MEN1	ENSG00000133895	-2.594007640324163	[1]	[0]	-9	hSpCas9	negative selection	12392791