Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 343930
• Symbol: MSGN1
• Description: mesogenin 1

DataSource: http://genomecrispr.dkfz.de/#!/results/MSGN1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
17816669	17816692	2	-	26472758	Jiyoye	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	-0.8389852057635243	[101]	[42]	-5	hSpCas9	negative selection	102778
17816645	17816668	2	-	26472758	Jiyoye	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-3.160509127783447	[82]	[6]	-9	hSpCas9	negative selection	102779
17816714	17816737	2	+	26472758	Jiyoye	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	1.0770267798135427	[21]	[34]	7	hSpCas9	negative selection	102780
17816819	17816842	2	+	26472758	Jiyoye	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	1.3098781801509585	[114]	[214]	7	hSpCas9	negative selection	102781
17816874	17816897	2	+	26472758	Jiyoye	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	-0.264695184438448	[324]	[203]	-2	hSpCas9	negative selection	102782
17816934	17816957	2	-	26472758	Jiyoye	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	1.0592520780855665	[118]	[186]	7	hSpCas9	negative selection	102783
17816956	17816979	2	-	26472758	Jiyoye	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	-0.5928246184941265	[159]	[79]	-4	hSpCas9	negative selection	102784
17817025	17817048	2	+	26472758	Jiyoye	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	-1.632352982680764	[184]	[44]	-8	hSpCas9	negative selection	102785
17817067	17817090	2	-	26472758	Jiyoye	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	0.958585322516003	[57]	[84]	6	hSpCas9	negative selection	102786
17816527	17816550	2	-	26472758	Jiyoye	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	-0.025784025770232866	[53]	[39]	0	hSpCas9	negative selection	102787
17816669	17816692	2	-	26472758	KBM7	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	-0.5492617978995772	[415,139]	[80,88]	-5	hSpCas9	negative selection	293896
17816645	17816668	2	-	26472758	KBM7	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-1.7220169524265312	[319,338]	[59,35]	-8	hSpCas9	negative selection	293897
17816714	17816737	2	+	26472758	KBM7	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	1.653434484488753	[120,46]	[189,55]	9	hSpCas9	negative selection	293898
17816819	17816842	2	+	26472758	KBM7	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	0.5705364660429684	[512,447]	[356,314]	6	hSpCas9	negative selection	293899
17816874	17816897	2	+	26472758	KBM7	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	0.23906540106022006	[725,516]	[356,325]	2	hSpCas9	negative selection	293900
17816934	17816957	2	-	26472758	KBM7	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	0.7186956669386609	[388,418]	[365,269]	7	hSpCas9	negative selection	293901
17816956	17816979	2	-	26472758	KBM7	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	0.9533382417902532	[348,314]	[336,270]	9	hSpCas9	negative selection	293902
17817025	17817048	2	+	26472758	KBM7	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	-0.12922563772370488	[405,575]	[180,246]	-1	hSpCas9	negative selection	293903
17817067	17817090	2	-	26472758	KBM7	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	0.03424522258565821	[267,118]	[71,105]	0	hSpCas9	negative selection	293904
17816527	17816550	2	-	26472758	KBM7	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	1.8985949036644556	[44,58]	[19,157]	9	hSpCas9	negative selection	293905
17816669	17816692	2	-	26472758	Raji	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	0.5753699146014024	[106]	[36]	5	hSpCas9	negative selection	485014
17816645	17816668	2	-	26472758	Raji	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-1.136070501490678	[160]	[16]	-7	hSpCas9	negative selection	485015
17816714	17816737	2	+	26472758	Raji	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	0.3000286133159955	[41]	[11]	3	hSpCas9	negative selection	485016
17816819	17816842	2	+	26472758	Raji	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	-0.07871275673985839	[313]	[68]	0	hSpCas9	negative selection	485017
17816874	17816897	2	+	26472758	Raji	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	1.0320954080693623	[235]	[111]	8	hSpCas9	negative selection	485018
17816934	17816957	2	-	26472758	Raji	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	0.2708822676564787	[199]	[55]	2	hSpCas9	negative selection	485019
17816956	17816979	2	-	26472758	Raji	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	0.0592892471725544	[243]	[58]	0	hSpCas9	negative selection	485020
17817025	17817048	2	+	26472758	Raji	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	0.4047694459981703	[165]	[50]	4	hSpCas9	negative selection	485021
17817067	17817090	2	-	26472758	Raji	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	0.4635273455988749	[124]	[39]	4	hSpCas9	negative selection	485022
17816527	17816550	2	-	26472758	Raji	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	1.1777728632649977	[39]	[20]	8	hSpCas9	negative selection	485023
17816669	17816692	2	-	26472758	K562	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	-1.4076579689132462	[175]	[55]	-6	hSpCas9	negative selection	676132
17816645	17816668	2	-	26472758	K562	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-2.2538321398613785	[225]	[39]	-7	hSpCas9	negative selection	676133
17816714	17816737	2	+	26472758	K562	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	1.022026306329999	[83]	[143]	8	hSpCas9	negative selection	676134
17816819	17816842	2	+	26472758	K562	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	-0.5489429223116575	[512]	[295]	-3	hSpCas9	negative selection	676135
17816874	17816897	2	+	26472758	K562	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	0.14981634177385528	[708]	[663]	1	hSpCas9	negative selection	676136
17816934	17816957	2	-	26472758	K562	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	-0.44557924375299857	[412]	[255]	-3	hSpCas9	negative selection	676137
17816956	17816979	2	-	26472758	K562	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	0.5533088224300244	[288]	[357]	4	hSpCas9	negative selection	676138
17817025	17817048	2	+	26472758	K562	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	0.19449350233476442	[293]	[283]	1	hSpCas9	negative selection	676139
17817067	17817090	2	-	26472758	K562	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	-0.12641896770186212	[149]	[115]	-1	hSpCas9	negative selection	676140
17816527	17816550	2	-	26472758	K562	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	-0.530021571918422	[64]	[37]	-3	hSpCas9	negative selection	676141
17816500	17816523	2	+	26627737	DLD1	viability	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	-3.1021584936704696	[94]	[0,8,0]	-9	hSpCas9	negative selection	809487
17816593	17816616	2	+	26627737	DLD1	viability	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.1085546675809945	[438]	[74,191,118]	-1	hSpCas9	negative selection	809488
17816621	17816644	2	-	26627737	DLD1	viability	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	1.321486833482215	[59]	[72,22,43]	9	hSpCas9	negative selection	809489
17816662	17816685	2	-	26627737	DLD1	viability	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	-0.008732302766587097	[219]	[68,113,29]	0	hSpCas9	negative selection	809490
17816877	17816900	2	+	26627737	DLD1	viability	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	-0.03189124052739811	[585]	[179,128,219]	0	hSpCas9	negative selection	809491
17816500	17816523	2	+	26627737	GBM cells	viability after 5 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	0.16900303825342977	[33]	[32,7]	2	hSpCas9	negative selection	891802
17816593	17816616	2	+	26627737	GBM cells	viability after 5 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.8163566481812018	[219]	[79,53]	-8	hSpCas9	negative selection	891803
17816621	17816644	2	-	26627737	GBM cells	viability after 5 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.3436987175585813	[107]	[56,89]	5	hSpCas9	negative selection	891804
17816662	17816685	2	-	26627737	GBM cells	viability after 5 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	0.1307295501087593	[108]	[68,58]	2	hSpCas9	negative selection	891805
17816877	17816900	2	+	26627737	GBM cells	viability after 5 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.3193046086587363	[268]	[205,153]	5	hSpCas9	negative selection	891806
17816500	17816523	2	+	26627737	GBM cells	viability after 13 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	0.5612666209483428	[33]	[56,2]	7	hSpCas9	negative selection	974117
17816593	17816616	2	+	26627737	GBM cells	viability after 13 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.583973808700862	[219]	[104,58]	-6	hSpCas9	negative selection	974118
17816621	17816644	2	-	26627737	GBM cells	viability after 13 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.6268270573656477	[107]	[95,85]	7	hSpCas9	negative selection	974119
17816662	17816685	2	-	26627737	GBM cells	viability after 13 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	0.15541690840687927	[108]	[77,55]	2	hSpCas9	negative selection	974120
17816877	17816900	2	+	26627737	GBM cells	viability after 13 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.3553779619566153	[268]	[253,131]	4	hSpCas9	negative selection	974121
17816500	17816523	2	+	26627737	GBM cells	viability after 21 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	-1.207229541634681	[33]	[7,7]	-7	hSpCas9	negative selection	1056432
17816593	17816616	2	+	26627737	GBM cells	viability after 21 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.6295596360465877	[219]	[82,71]	-5	hSpCas9	negative selection	1056433
17816621	17816644	2	-	26627737	GBM cells	viability after 21 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.9667878406915995	[107]	[133,96]	8	hSpCas9	negative selection	1056434
17816662	17816685	2	-	26627737	GBM cells	viability after 21 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	1.4432645166622904	[108]	[171,150]	9	hSpCas9	negative selection	1056435
17816877	17816900	2	+	26627737	GBM cells	viability after 21 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.10930145566454823	[268]	[165,149]	1	hSpCas9	negative selection	1056436
17816500	17816523	2	+	26627737	RPE1	viability after 9 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	9.720225440180686	[0]	[267,258]	9	hSpCas9	negative selection	1138747
17816593	17816616	2	+	26627737	RPE1	viability after 9 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-2.757538565746837	[790]	[33,39]	-9	hSpCas9	negative selection	1138748
17816621	17816644	2	-	26627737	RPE1	viability after 9 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	-0.1410730878932145	[495]	[173,97]	-1	hSpCas9	negative selection	1138749
17816662	17816685	2	-	26627737	RPE1	viability after 9 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	1.341119943709664	[343]	[257,291]	7	hSpCas9	negative selection	1138750
17816877	17816900	2	+	26627737	RPE1	viability after 9 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	-0.4140757958983409	[779]	[222,131]	-3	hSpCas9	negative selection	1138751
17816500	17816523	2	+	26627737	RPE1	viability after 12 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	10.422247311393978	[0]	[441,290]	9	hSpCas9	negative selection	1221062
17816593	17816616	2	+	26627737	RPE1	viability after 12 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-2.765308466952064	[790]	[39,21]	-9	hSpCas9	negative selection	1221063
17816621	17816644	2	-	26627737	RPE1	viability after 12 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.6810688401994651	[495]	[201,225]	4	hSpCas9	negative selection	1221064
17816662	17816685	2	-	26627737	RPE1	viability after 12 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	1.505313470274221	[343]	[274,248]	8	hSpCas9	negative selection	1221065
17816877	17816900	2	+	26627737	RPE1	viability after 12 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	-0.34339856200456187	[779]	[170,158]	-2	hSpCas9	negative selection	1221066
17816500	17816523	2	+	26627737	RPE1	viability after 15 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	11.488880489705974	[0]	[952,677]	10	hSpCas9	negative selection	1303377
17816593	17816616	2	+	26627737	RPE1	viability after 15 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-1.7350751453274809	[790]	[26,105]	-8	hSpCas9	negative selection	1303378
17816621	17816644	2	-	26627737	RPE1	viability after 15 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.2914432613187604	[495]	[271,74]	2	hSpCas9	negative selection	1303379
17816662	17816685	2	-	26627737	RPE1	viability after 15 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	1.4965269125948395	[343]	[382,169]	7	hSpCas9	negative selection	1303380
17816877	17816900	2	+	26627737	RPE1	viability after 15 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	-0.29548835859394285	[779]	[163,194]	-2	hSpCas9	negative selection	1303381
17816500	17816523	2	+	26627737	RPE1	viability after 18 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	11.545381246350335	[0]	[794,818]	10	hSpCas9	negative selection	1385692
17816593	17816616	2	+	26627737	RPE1	viability after 18 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-2.0563524095725945	[790]	[16,87]	-8	hSpCas9	negative selection	1385693
17816621	17816644	2	-	26627737	RPE1	viability after 18 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	-0.020703828245336342	[495]	[144,117]	0	hSpCas9	negative selection	1385694
17816662	17816685	2	-	26627737	RPE1	viability after 18 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	1.448287616378733	[343]	[262,242]	7	hSpCas9	negative selection	1385695
17816877	17816900	2	+	26627737	RPE1	viability after 18 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.04738242693387071	[779]	[159,278]	0	hSpCas9	negative selection	1385696
17816500	17816523	2	+	26627737	HeLa	viability after 8 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	3.056355826456035	[25]	[170,133,0]	9	hSpCas9	negative selection	1468007
17816593	17816616	2	+	26627737	HeLa	viability after 8 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.5396526448668985	[380]	[237,10,119]	-5	hSpCas9	negative selection	1468008
17816621	17816644	2	-	26627737	HeLa	viability after 8 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	1.762005773982247	[75]	[197,83,75]	9	hSpCas9	negative selection	1468009
17816662	17816685	2	-	26627737	HeLa	viability after 8 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	-0.031382138559605366	[203]	[163,62,52]	0	hSpCas9	negative selection	1468010
17816877	17816900	2	+	26627737	HeLa	viability after 8 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	-0.4611984551633921	[609]	[130,228,203]	-4	hSpCas9	negative selection	1468011
17816500	17816523	2	+	26627737	HeLa	viability after 12 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	1.187308879127626	[25]	[0,2,70]	8	hSpCas9	negative selection	1550322
17816593	17816616	2	+	26627737	HeLa	viability after 12 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.4326157077018427	[380]	[164,91,96]	-4	hSpCas9	negative selection	1550323
17816621	17816644	2	-	26627737	HeLa	viability after 12 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	1.8115179304015583	[75]	[77,164,80]	9	hSpCas9	negative selection	1550324
17816662	17816685	2	-	26627737	HeLa	viability after 12 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	0.817224922745153	[203]	[255,51,150]	6	hSpCas9	negative selection	1550325
17816877	17816900	2	+	26627737	HeLa	viability after 12 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	-0.22308864494845831	[609]	[335,200,115]	-2	hSpCas9	negative selection	1550326
17816500	17816523	2	+	26627737	HeLa	viability after 15 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	2.07274100260286	[25]	[0,29,107]	9	hSpCas9	negative selection	1632637
17816593	17816616	2	+	26627737	HeLa	viability after 15 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.7714180663975845	[380]	[126,67,75]	-6	hSpCas9	negative selection	1632638
17816621	17816644	2	-	26627737	HeLa	viability after 15 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	1.9323598392122812	[75]	[119,94,140]	9	hSpCas9	negative selection	1632639
17816662	17816685	2	-	26627737	HeLa	viability after 15 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	0.4208306407387482	[203]	[129,155,41]	3	hSpCas9	negative selection	1632640
17816877	17816900	2	+	26627737	HeLa	viability after 15 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.09397091130116975	[609]	[116,318,368]	0	hSpCas9	negative selection	1632641
17816500	17816523	2	+	26627737	HeLa	viability after 18 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	2.067006770355816	[25]	[0,23,107]	9	hSpCas9	negative selection	1714952
17816593	17816616	2	+	26627737	HeLa	viability after 18 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.6986602781617828	[380]	[96,52,75]	-6	hSpCas9	negative selection	1714953
17816621	17816644	2	-	26627737	HeLa	viability after 18 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	1.9557463929055188	[75]	[83,78,140]	9	hSpCas9	negative selection	1714954
17816662	17816685	2	-	26627737	HeLa	viability after 18 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	0.43963119901786973	[203]	[82,137,41]	3	hSpCas9	negative selection	1714955
17816877	17816900	2	+	26627737	HeLa	viability after 18 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.09056601367385253	[609]	[82,256,368]	0	hSpCas9	negative selection	1714956
17816500	17816523	2	+	26627737	HCT116	viability after 6 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	2.1799735532971294	[137]	[116,87]	9	hSpCas9	negative selection	1797267
17816593	17816616	2	+	26627737	HCT116	viability after 6 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	0.591746848301944	[746]	[292,112]	3	hSpCas9	negative selection	1797268
17816621	17816644	2	-	26627737	HCT116	viability after 6 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	-2.003202004355974	[462]	[12,20]	-8	hSpCas9	negative selection	1797269
17816662	17816685	2	-	26627737	HCT116	viability after 6 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	1.0092815913792792	[368]	[41,157]	5	hSpCas9	negative selection	1797270
17816877	17816900	2	+	26627737	HCT116	viability after 6 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.5790150369464937	[641]	[347,41]	3	hSpCas9	negative selection	1797271
17816500	17816523	2	+	26627737	HCT116	viability after 8 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	5.069330358496662	[0]	[0,19,33]	9	hSpCas9	negative selection	1879582
17816593	17816616	2	+	26627737	HCT116	viability after 8 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.646363515252649	[350]	[100,120,147]	-7	hSpCas9	negative selection	1879583
17816621	17816644	2	-	26627737	HCT116	viability after 8 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	-0.17031525208703113	[168]	[70,89,86]	-2	hSpCas9	negative selection	1879584
17816662	17816685	2	-	26627737	HCT116	viability after 8 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	0.3721466668075366	[200]	[170,153,105]	4	hSpCas9	negative selection	1879585
17816877	17816900	2	+	26627737	HCT116	viability after 8 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.5462110831557804	[289]	[308,209,182]	5	hSpCas9	negative selection	1879586
17816500	17816523	2	+	26627737	HCT116	viability after 9 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	-0.874475713530666	[137]	[42,1]	-6	hSpCas9	negative selection	1961897
17816593	17816616	2	+	26627737	HCT116	viability after 9 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	0.27291471479419316	[746]	[240,240]	2	hSpCas9	negative selection	1961898
17816621	17816644	2	-	26627737	HCT116	viability after 9 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	-0.40639383539594637	[462]	[61,117]	-3	hSpCas9	negative selection	1961899
17816662	17816685	2	-	26627737	HCT116	viability after 9 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	0.7244856617244108	[368]	[302,51]	5	hSpCas9	negative selection	1961900
17816877	17816900	2	+	26627737	HCT116	viability after 9 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	-0.902689066141742	[641]	[127,62]	-6	hSpCas9	negative selection	1961901
17816500	17816523	2	+	26627737	HCT116	viability after 12 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	4.66232986198386	[0]	[23,13,0]	9	hSpCas9	negative selection	2044212
17816593	17816616	2	+	26627737	HCT116	viability after 12 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.5680367587817355	[350]	[120,141,110]	-6	hSpCas9	negative selection	2044213
17816621	17816644	2	-	26627737	HCT116	viability after 12 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	-0.8090980053140868	[168]	[40,53,57]	-7	hSpCas9	negative selection	2044214
17816662	17816685	2	-	26627737	HCT116	viability after 12 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	0.03118985705813515	[200]	[134,130,55]	0	hSpCas9	negative selection	2044215
17816877	17816900	2	+	26627737	HCT116	viability after 12 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.8412612036241544	[289]	[312,246,254]	7	hSpCas9	negative selection	2044216
17816500	17816523	2	+	26627737	HCT116	viability after 15 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	5.1752387294089495	[0]	[18,18,23]	9	hSpCas9	negative selection	2126527
17816593	17816616	2	+	26627737	HCT116	viability after 15 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.5428441863877655	[350]	[173,70,173]	-5	hSpCas9	negative selection	2126528
17816621	17816644	2	-	26627737	HCT116	viability after 15 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	-0.4153705490200621	[168]	[57,41,115]	-4	hSpCas9	negative selection	2126529
17816662	17816685	2	-	26627737	HCT116	viability after 15 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	-0.11870989256105902	[200]	[92,90,132]	-1	hSpCas9	negative selection	2126530
17816877	17816900	2	+	26627737	HCT116	viability after 15 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.6667051504553101	[289]	[283,202,307]	6	hSpCas9	negative selection	2126531
17816500	17816523	2	+	26627737	HCT116	viability after 18 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	5.267521269587549	[0]	[15,9,30]	9	hSpCas9	negative selection	2208842
17816593	17816616	2	+	26627737	HCT116	viability after 18 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.5377842797907261	[350]	[119,146,79]	-5	hSpCas9	negative selection	2208843
17816621	17816644	2	-	26627737	HCT116	viability after 18 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	-0.44032400971875574	[168]	[86,28,66]	-4	hSpCas9	negative selection	2208844
17816662	17816685	2	-	26627737	HCT116	viability after 18 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	-0.0013004107999756709	[200]	[118,115,52]	0	hSpCas9	negative selection	2208845
17816877	17816900	2	+	26627737	HCT116	viability after 18 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.685323215505586	[289]	[300,128,253]	5	hSpCas9	negative selection	2208846
17816548	17816571	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGAGCCCAAGCCATCCTCGAGG	MSGN1	ENSG00000151379	-0.09203637633030176	[2,2]	[3,0]	-1	hSpCas9	positive selection	3003487
17816717	17816740	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCCCTGTGAGCACGGCGGGG	MSGN1	ENSG00000151379	-0.5187437093858607	[3,2]	[3,0]	-6	hSpCas9	positive selection	3003488
17816588	17816611	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGTCTTCCTGGGACTGGAAGG	MSGN1	ENSG00000151379	-0.2733180766109995	[4,4]	[4,1]	-4	hSpCas9	positive selection	3003489
17816661	17816684	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATTCCAGCGATGGAGCCGGGG	MSGN1	ENSG00000151379	-0.2716764956342012	[1,2]	[2,0]	-4	hSpCas9	positive selection	3003490
17816548	17816571	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGAGCCCAAGCCATCCTCGAGG	MSGN1	ENSG00000151379	-0.050282598939447476	[2,2]	[1,1]	0	hSpCas9	positive selection	3071345
17816717	17816740	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCCCTGTGAGCACGGCGGGG	MSGN1	ENSG00000151379	-0.5089952913575064	[3,3]	[2,0]	-7	hSpCas9	positive selection	3071346
17816588	17816611	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGTCTTCCTGGGACTGGAAGG	MSGN1	ENSG00000151379	0.545771094512766	[4,4]	[3,4]	8	hSpCas9	positive selection	3071347
17816661	17816684	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATTCCAGCGATGGAGCCGGGG	MSGN1	ENSG00000151379	-0.23315310658761124	[1,1]	[1,0]	-3	hSpCas9	positive selection	3071348
17817088	17817111		-	24336571	A375	resistance to PLX after 7 days	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.15876244723283683	[9,7]	[10,9]	5	hSpCas9	positive selection	3128632
17817030	17817053		-	24336571	A375	resistance to PLX after 7 days	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	-0.3348113555280019	[8,7]	[5,6]	-8	hSpCas9	positive selection	3128633
17817061	17817084		-	24336571	A375	resistance to PLX after 7 days	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.04336195413902777	[5,8]	[6,7]	1	hSpCas9	positive selection	3128634
17817088	17817111		-	24336571	A375	resistance to PLX after 14 days	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.2457323982437482	[10,10]	[4,5]	2	hSpCas9	positive selection	3186425
17817030	17817053		-	24336571	A375	resistance to PLX after 14 days	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	-0.8722161350093832	[9,10]	[1,1]	-8	hSpCas9	positive selection	3186426
17817061	17817084		-	24336571	A375	resistance to PLX after 14 days	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.3716707961826029	[2,9]	[2,3]	3	hSpCas9	positive selection	3186427
17817088	17817111		-	24336571	A375	viability after 7 days	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.12506027084619853	[8]	[9,7]	2	hSpCas9	negative selection	3244218
17817030	17817053		-	24336571	A375	viability after 7 days	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	-0.1698011537408613	[9]	[8,7]	-2	hSpCas9	negative selection	3244219
17817061	17817084		-	24336571	A375	viability after 7 days	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.3745629305942616	[5]	[5,8]	6	hSpCas9	negative selection	3244220
17817088	17817111		-	24336571	A375	viability after 14 days	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.37261790737731726	[8]	[10,10]	5	hSpCas9	negative selection	3302011
17817030	17817053		-	24336571	A375	viability after 14 days	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.1494591597409613	[9]	[9,10]	2	hSpCas9	negative selection	3302012
17817061	17817084		-	24336571	A375	viability after 14 days	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.09739582687989023	[5]	[2,9]	1	hSpCas9	negative selection	3302013
17817088	17817111	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.5024387092823666	[107,107]	[0,0]	2	hSpCas9	positive selection	3380158
17816947	17816970	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.16893854325626279	[171,171]	[0,0]	-1	hSpCas9	positive selection	3380159
17817050	17817073	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	-0.19388490038649384	[174,174]	[0,0]	-1	hSpCas9	positive selection	3380160
17816548	17816571	2	-	26780180	HT29	viability (Avana library 4 designs)	AGGAGCCCAAGCCATCCTCGAGG	MSGN1	ENSG00000151379	0.287542116025141	[]	[]	1	hSpCas9	negative selection	3441259
17816716	17816739	2	+	26780180	HT29	viability (Avana library 4 designs)	GCTGCCCTGTGAGCACGGCGGGG	MSGN1	ENSG00000151379	1.85165610076097	[]	[]	7	hSpCas9	negative selection	3441260
17816587	17816610	2	+	26780180	HT29	viability (Avana library 4 designs)	GCTGTCTTCCTGGGACTGGAAGG	MSGN1	ENSG00000151379	-0.969909924393545	[]	[]	-9	hSpCas9	negative selection	3441261
17816661	17816684	2	-	26780180	HT29	viability (Avana library 4 designs)	GGATTCCAGCGATGGAGCCGGGG	MSGN1	ENSG00000151379	1.44525851614755	[]	[]	5	hSpCas9	negative selection	3441262
17816716	17816739	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCCCTGTGAGCACGGCGGGG	MSGN1	ENSG00000151379	0.0896534742314128	[]	[]	0	hSpCas9	negative selection	3531871
17816548	17816571	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGAGCCCAAGCCATCCTCGAGG	MSGN1	ENSG00000151379	6.96109675814919	[]	[]	9	hSpCas9	negative selection	3531872
17816661	17816684	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATTCCAGCGATGGAGCCGGGG	MSGN1	ENSG00000151379	3.32645794039273	[]	[]	5	hSpCas9	negative selection	3531873
17816587	17816610	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTCTTCCTGGGACTGGAAGG	MSGN1	ENSG00000151379	-0.217981454024846	[]	[]	0	hSpCas9	negative selection	3531874
17816578	17816601	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCCAGGAAGACAGCAGGCCAGGG	MSGN1	ENSG00000151379	7.01200229734805	[]	[]	9	hSpCas9	negative selection	3531875
17816527	17816550	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	-0.808994170930328	[]	[]	-1	hSpCas9	negative selection	3531876
17816716	17816739	2	+	26780180	A375	viability (Avana lentiGuide)	GCTGCCCTGTGAGCACGGCGGGG	MSGN1	ENSG00000151379	5.30564457432767	[]	[]	5	hSpCas9	negative selection	3640530
17816548	17816571	2	-	26780180	A375	viability (Avana lentiGuide)	AGGAGCCCAAGCCATCCTCGAGG	MSGN1	ENSG00000151379	2.41349657469591	[]	[]	2	hSpCas9	negative selection	3640531
17816661	17816684	2	-	26780180	A375	viability (Avana lentiGuide)	GGATTCCAGCGATGGAGCCGGGG	MSGN1	ENSG00000151379	17.9462345769937	[]	[]	8	hSpCas9	negative selection	3640532
17816587	17816610	2	+	26780180	A375	viability (Avana lentiGuide)	GCTGTCTTCCTGGGACTGGAAGG	MSGN1	ENSG00000151379	-0.528554188725946	[]	[]	-1	hSpCas9	negative selection	3640533
17816578	17816601	2	-	26780180	A375	viability (Avana lentiGuide)	CCCAGGAAGACAGCAGGCCAGGG	MSGN1	ENSG00000151379	-5.32189889702973	[]	[]	-8	hSpCas9	negative selection	3640534
17816527	17816550	2	-	26780180	A375	viability (Avana lentiGuide)	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	1.36440299319144	[]	[]	1	hSpCas9	negative selection	3640535
17816716	17816739	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCCCTGTGAGCACGGCGGGG	MSGN1	ENSG00000151379	-0.13110348331295457	[3]	[3,3]	-2	hSpCas9	positive selection	3749189
17816548	17816571	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGAGCCCAAGCCATCCTCGAGG	MSGN1	ENSG00000151379	0.3060969785926955	[3]	[5,3]	8	hSpCas9	positive selection	3749190
17816661	17816684	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATTCCAGCGATGGAGCCGGGG	MSGN1	ENSG00000151379	0.1792390582823829	[4]	[4,4]	5	hSpCas9	positive selection	3749191
17816587	17816610	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTCTTCCTGGGACTGGAAGG	MSGN1	ENSG00000151379	0.2561208528061551	[5]	[6,6]	7	hSpCas9	positive selection	3749192
17816578	17816601	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCCAGGAAGACAGCAGGCCAGGG	MSGN1	ENSG00000151379	0.3912999976033136	[3]	[5,4]	9	hSpCas9	positive selection	3749193
17816527	17816550	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	-0.09123102454319329	[4]	[4,3]	-1	hSpCas9	positive selection	3749194
17816716	17816739	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCCCTGTGAGCACGGCGGGG	MSGN1	ENSG00000151379	0.11343089026636548	[5]	[3,5]	2	hSpCas9	positive selection	3857796
17816548	17816571	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGAGCCCAAGCCATCCTCGAGG	MSGN1	ENSG00000151379	-0.5409825515977986	[4]	[1,2]	-6	hSpCas9	positive selection	3857797
17816661	17816684	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATTCCAGCGATGGAGCCGGGG	MSGN1	ENSG00000151379	-1.0178939507142934	[3]	[0,1]	-8	hSpCas9	positive selection	3857798
17816587	17816610	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTCTTCCTGGGACTGGAAGG	MSGN1	ENSG00000151379	0.03541295438401343	[6]	[6,4]	0	hSpCas9	positive selection	3857799
17816578	17816601	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCCAGGAAGACAGCAGGCCAGGG	MSGN1	ENSG00000151379	0.23188595203885126	[4]	[5,4]	6	hSpCas9	positive selection	3857800
17816527	17816550	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	-0.24471468230089946	[5]	[4,2]	-3	hSpCas9	positive selection	3857801
17817088	17817111	2	-	26780180	A375	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.934792704472452	[]	[]	4	hSpCas9	negative selection	3969190
17817050	17817073	2	+	26780180	A375	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.657323788585343	[]	[]	2	hSpCas9	negative selection	3969191
17817030	17817053	2	-	26780180	A375	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.418682911308827	[]	[]	1	hSpCas9	negative selection	3969192
17816947	17816970	2	-	26780180	A375	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	1.77120007932234	[]	[]	9	hSpCas9	negative selection	3969193
17816785	17816808	2	-	26780180	A375	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	1.66714895728636	[]	[]	9	hSpCas9	negative selection	3969194
17817061	17817084	2	-	26780180	A375	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.246622972007604	[]	[]	0	hSpCas9	negative selection	3969195
17817088	17817111	2	-	26780180	HT29	viability (GeCKOv2 library)	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	1.37649866866186	[]	[]	7	hSpCas9	negative selection	4077156
17817050	17817073	2	+	26780180	HT29	viability (GeCKOv2 library)	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.288656851346647	[]	[]	0	hSpCas9	negative selection	4077157
17817030	17817053	2	-	26780180	HT29	viability (GeCKOv2 library)	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.490627316704483	[]	[]	1	hSpCas9	negative selection	4077158
17816947	17816970	2	-	26780180	HT29	viability (GeCKOv2 library)	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	1.95180866500868	[]	[]	9	hSpCas9	negative selection	4077159
17816785	17816808	2	-	26780180	HT29	viability (GeCKOv2 library)	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	1.34662002476169	[]	[]	6	hSpCas9	negative selection	4077160
17817061	17817084	2	-	26780180	HT29	viability (GeCKOv2 library)	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.403436288937471	[]	[]	1	hSpCas9	negative selection	4077161
17817088	17817111	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.31811907099788694	[3]	[2,2]	7	hSpCas9	positive selection	4153102
17817030	17817053	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.10073439211745405	[2]	[2,0]	2	hSpCas9	positive selection	4153103
17817061	17817084	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.05262958701334187	[3]	[2,1]	1	hSpCas9	positive selection	4153104
17817088	17817111	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.24369709715571058	[4]	[4,0,4,0]	2	hSpCas9	positive selection	4217124
17817030	17817053	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	-0.8055492662629098	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4217125
17817061	17817084	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	-0.3914234654298401	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4217126
17817061	17817084	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.18284047865477704	[1]	[1,0]	3	hSpCas9	positive selection	4283844
17817030	17817053	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	-0.20165185825308918	[1]	[1,0]	-4	hSpCas9	positive selection	4283845
17816785	17816808	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	-0.28732734075721217	[4]	[4,1]	-5	hSpCas9	positive selection	4283846
17817088	17817111	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.08588885627097007	[2]	[1,1]	-2	hSpCas9	positive selection	4348102
17816947	17816970	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	0.009847119512713942	[2]	[1,1]	0	hSpCas9	positive selection	4348103
17817050	17817073	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	-0.10987417554337668	[3]	[3,1]	-2	hSpCas9	positive selection	4348104
17816621	17816643	2	-	27760321	OCIAML3	viability	AGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.5690797934649782	[359,255]	[340,369]	6	hSpCas9	negative selection	4419740
17816663	17816685	2	-	27760321	OCIAML3	viability	AGGATTCCAGCGATGGAGCCGG	MSGN1	ENSG00000151379	-0.6754288308859767	[510,498]	[302,175]	-6	hSpCas9	negative selection	4419741
17816721	17816743	2	-	27760321	OCIAML3	viability	CTGGCCCCGCCGTGCTCACAGG	MSGN1	ENSG00000151379	-0.7583999933844179	[708,677]	[268,388]	-6	hSpCas9	negative selection	4419742
17816778	17816800	2	-	27760321	OCIAML3	viability	TCCACCTCTACCAGGCCACTGG	MSGN1	ENSG00000151379	0.8477633899886875	[851,747]	[1078,1181]	8	hSpCas9	negative selection	4419743
17816826	17816848	2	-	27760321	OCIAML3	viability	CCACCACCGCCCTGAAGGTGGG	MSGN1	ENSG00000151379	0.5300164475660222	[820,682]	[796,908]	6	hSpCas9	negative selection	4419744
17816621	17816643	2	-	27760321	OCIAML2	viability	AGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.48586414876392814	[359,255]	[330,363]	6	hSpCas9	negative selection	4503203
17816663	17816685	2	-	27760321	OCIAML2	viability	AGGATTCCAGCGATGGAGCCGG	MSGN1	ENSG00000151379	0.4856671848559273	[510,498]	[521,640]	6	hSpCas9	negative selection	4503204
17816721	17816743	2	-	27760321	OCIAML2	viability	CTGGCCCCGCCGTGCTCACAGG	MSGN1	ENSG00000151379	0.22638213371313787	[708,677]	[532,820]	3	hSpCas9	negative selection	4503205
17816778	17816800	2	-	27760321	OCIAML2	viability	TCCACCTCTACCAGGCCACTGG	MSGN1	ENSG00000151379	0.5676554638616945	[851,747]	[863,1079]	7	hSpCas9	negative selection	4503206
17816826	17816848	2	-	27760321	OCIAML2	viability	CCACCACCGCCCTGAAGGTGGG	MSGN1	ENSG00000151379	0.17269318359379737	[820,682]	[526,887]	2	hSpCas9	negative selection	4503207
17816621	17816643	2	-	27760321	MV411	viability	AGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	1.1891769959633018	[359,255]	[402,541]	8	hSpCas9	negative selection	4586666
17816663	17816685	2	-	27760321	MV411	viability	AGGATTCCAGCGATGGAGCCGG	MSGN1	ENSG00000151379	0.11437821914925392	[510,498]	[335,399]	0	hSpCas9	negative selection	4586667
17816721	17816743	2	-	27760321	MV411	viability	CTGGCCCCGCCGTGCTCACAGG	MSGN1	ENSG00000151379	-1.5626499973410044	[708,677]	[93,246]	-7	hSpCas9	negative selection	4586668
17816778	17816800	2	-	27760321	MV411	viability	TCCACCTCTACCAGGCCACTGG	MSGN1	ENSG00000151379	-0.12993948579449144	[851,747]	[313,732]	-1	hSpCas9	negative selection	4586669
17816826	17816848	2	-	27760321	MV411	viability	CCACCACCGCCCTGAAGGTGGG	MSGN1	ENSG00000151379	0.22167115348234456	[820,682]	[341,927]	1	hSpCas9	negative selection	4586670
17816621	17816643	2	-	27760321	HL60	viability	AGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.6663432225778116	[359,255]	[380,409]	7	hSpCas9	negative selection	4670129
17816663	17816685	2	-	27760321	HL60	viability	AGGATTCCAGCGATGGAGCCGG	MSGN1	ENSG00000151379	0.7639356431197785	[510,498]	[606,802]	8	hSpCas9	negative selection	4670130
17816721	17816743	2	-	27760321	HL60	viability	CTGGCCCCGCCGTGCTCACAGG	MSGN1	ENSG00000151379	-0.3405838689965306	[708,677]	[448,446]	-4	hSpCas9	negative selection	4670131
17816778	17816800	2	-	27760321	HL60	viability	TCCACCTCTACCAGGCCACTGG	MSGN1	ENSG00000151379	0.8883201308176999	[851,747]	[1311,1095]	8	hSpCas9	negative selection	4670132
17816826	17816848	2	-	27760321	HL60	viability	CCACCACCGCCCTGAAGGTGGG	MSGN1	ENSG00000151379	0.134986612094662	[820,682]	[544,805]	1	hSpCas9	negative selection	4670133
17816621	17816643	2	-	27760321	HT1080	viability	AGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	1.1091878417920171	[255,199]	[215,173]	6	hSpCas9	negative selection	4753592
17816663	17816685	2	-	27760321	HT1080	viability	AGGATTCCAGCGATGGAGCCGG	MSGN1	ENSG00000151379	-0.21500727010050366	[498,389]	[132,173]	-1	hSpCas9	negative selection	4753593
17816721	17816743	2	-	27760321	HT1080	viability	CTGGCCCCGCCGTGCTCACAGG	MSGN1	ENSG00000151379	0.3654434816305604	[677,528]	[366,246]	2	hSpCas9	negative selection	4753594
17816778	17816800	2	-	27760321	HT1080	viability	TCCACCTCTACCAGGCCACTGG	MSGN1	ENSG00000151379	1.0508344951111566	[747,583]	[468,637]	6	hSpCas9	negative selection	4753595
17816826	17816848	2	-	27760321	HT1080	viability	CCACCACCGCCCTGAAGGTGGG	MSGN1	ENSG00000151379	0.09548405332636167	[682,532]	[211,309]	0	hSpCas9	negative selection	4753596
17816621	17816643	2	-	27760321	HT29	viability after 7 days	AGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.5101628339104309	[255,199]	[476,478,307]	7	hSpCas9	negative selection	4837055
17816663	17816685	2	-	27760321	HT29	viability after 7 days	AGGATTCCAGCGATGGAGCCGG	MSGN1	ENSG00000151379	0.21215397456087892	[498,389]	[641,822,521]	3	hSpCas9	negative selection	4837056
17816721	17816743	2	-	27760321	HT29	viability after 7 days	CTGGCCCCGCCGTGCTCACAGG	MSGN1	ENSG00000151379	-0.448658033806445	[677,528]	[865,592,296]	-6	hSpCas9	negative selection	4837057
17816778	17816800	2	-	27760321	HT29	viability after 7 days	TCCACCTCTACCAGGCCACTGG	MSGN1	ENSG00000151379	0.7500314377796902	[747,583]	[1442,1505,1371]	9	hSpCas9	negative selection	4837058
17816826	17816848	2	-	27760321	HT29	viability after 7 days	CCACCACCGCCCTGAAGGTGGG	MSGN1	ENSG00000151379	0.7116644300706995	[682,532]	[1721,939,1240]	9	hSpCas9	negative selection	4837059
17816621	17816643	2	-	27760321	HT29	viability after 25 days	AGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	1.0599900800070903	[255,199]	[505,550,577]	9	hSpCas9	negative selection	4920518
17816663	17816685	2	-	27760321	HT29	viability after 25 days	AGGATTCCAGCGATGGAGCCGG	MSGN1	ENSG00000151379	0.19457655423436815	[498,389]	[395,621,754]	2	hSpCas9	negative selection	4920519
17816721	17816743	2	-	27760321	HT29	viability after 25 days	CTGGCCCCGCCGTGCTCACAGG	MSGN1	ENSG00000151379	-0.27439500215160123	[677,528]	[538,548,629]	-3	hSpCas9	negative selection	4920520
17816778	17816800	2	-	27760321	HT29	viability after 25 days	TCCACCTCTACCAGGCCACTGG	MSGN1	ENSG00000151379	1.1945171868765934	[747,583]	[1960,1433,1822]	9	hSpCas9	negative selection	4920521
17816826	17816848	2	-	27760321	HT29	viability after 25 days	CCACCACCGCCCTGAAGGTGGG	MSGN1	ENSG00000151379	0.3360214836283423	[682,532]	[866,683,1102]	3	hSpCas9	negative selection	4920522
17816621	17816643	2	-	27760321	HT29	viability after 22 days	AGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	1.0726088034995782	[255,199]	[452,650,561]	9	hSpCas9	negative selection	5003981
17816663	17816685	2	-	27760321	HT29	viability after 22 days	AGGATTCCAGCGATGGAGCCGG	MSGN1	ENSG00000151379	0.07056477489714447	[498,389]	[350,637,635]	0	hSpCas9	negative selection	5003982
17816721	17816743	2	-	27760321	HT29	viability after 22 days	CTGGCCCCGCCGTGCTCACAGG	MSGN1	ENSG00000151379	-0.14099071475161873	[677,528]	[811,683,394]	-1	hSpCas9	negative selection	5003983
17816778	17816800	2	-	27760321	HT29	viability after 22 days	TCCACCTCTACCAGGCCACTGG	MSGN1	ENSG00000151379	0.976458016647419	[747,583]	[1359,1363,1827]	9	hSpCas9	negative selection	5003984
17816826	17816848	2	-	27760321	HT29	viability after 22 days	CCACCACCGCCCTGAAGGTGGG	MSGN1	ENSG00000151379	0.26849471176349293	[682,532]	[921,650,965]	2	hSpCas9	negative selection	5003985
17816621	17816643	2	-	27760321	HT29	viability after 19 days	AGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.7205080616311179	[255,199]	[420,493,374]	7	hSpCas9	negative selection	5087444
17816663	17816685	2	-	27760321	HT29	viability after 19 days	AGGATTCCAGCGATGGAGCCGG	MSGN1	ENSG00000151379	0.028204207377203916	[498,389]	[507,315,721]	0	hSpCas9	negative selection	5087445
17816721	17816743	2	-	27760321	HT29	viability after 19 days	CTGGCCCCGCCGTGCTCACAGG	MSGN1	ENSG00000151379	-0.18617694348807268	[677,528]	[704,630,497]	-2	hSpCas9	negative selection	5087446
17816778	17816800	2	-	27760321	HT29	viability after 19 days	TCCACCTCTACCAGGCCACTGG	MSGN1	ENSG00000151379	0.6805682607682622	[747,583]	[1510,1306,886]	7	hSpCas9	negative selection	5087447
17816826	17816848	2	-	27760321	HT29	viability after 19 days	CCACCACCGCCCTGAAGGTGGG	MSGN1	ENSG00000151379	0.36248931959688735	[682,532]	[1368,493,868]	3	hSpCas9	negative selection	5087448
17816621	17816643	2	-	27760321	HT29	viability after 16 days	AGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	1.2845315498785914	[255,199]	[872,390,629]	9	hSpCas9	negative selection	5170907
17816663	17816685	2	-	27760321	HT29	viability after 16 days	AGGATTCCAGCGATGGAGCCGG	MSGN1	ENSG00000151379	-0.14733348796257148	[498,389]	[691,298,382]	-1	hSpCas9	negative selection	5170908
17816721	17816743	2	-	27760321	HT29	viability after 16 days	CTGGCCCCGCCGTGCTCACAGG	MSGN1	ENSG00000151379	-0.3973899700431663	[677,528]	[631,514,401]	-4	hSpCas9	negative selection	5170909
17816778	17816800	2	-	27760321	HT29	viability after 16 days	TCCACCTCTACCAGGCCACTGG	MSGN1	ENSG00000151379	0.9757700138149947	[747,583]	[1601,1045,1771]	9	hSpCas9	negative selection	5170910
17816826	17816848	2	-	27760321	HT29	viability after 16 days	CCACCACCGCCCTGAAGGTGGG	MSGN1	ENSG00000151379	0.6226824439163859	[682,532]	[1267,732,1169]	7	hSpCas9	negative selection	5170911
17816621	17816643	2	-	27760321	HT29	viability after 13 days	AGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.8149840286573979	[255,199]	[648,526,233]	9	hSpCas9	negative selection	5254370
17816663	17816685	2	-	27760321	HT29	viability after 13 days	AGGATTCCAGCGATGGAGCCGG	MSGN1	ENSG00000151379	0.007872297670804884	[498,389]	[529,566,461]	0	hSpCas9	negative selection	5254371
17816721	17816743	2	-	27760321	HT29	viability after 13 days	CTGGCCCCGCCGTGCTCACAGG	MSGN1	ENSG00000151379	-0.0784103263045548	[677,528]	[830,652,513]	-1	hSpCas9	negative selection	5254372
17816778	17816800	2	-	27760321	HT29	viability after 13 days	TCCACCTCTACCAGGCCACTGG	MSGN1	ENSG00000151379	0.7081570184170949	[747,583]	[1182,1429,1178]	8	hSpCas9	negative selection	5254373
17816826	17816848	2	-	27760321	HT29	viability after 13 days	CCACCACCGCCCTGAAGGTGGG	MSGN1	ENSG00000151379	0.909322586581277	[682,532]	[1727,1004,1244]	9	hSpCas9	negative selection	5254374
17816621	17816643	2	-	27760321	HT29	viability after 10 days	AGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.8793749806518482	[255,199]	[403,756,418]	9	hSpCas9	negative selection	5337833
17816663	17816685	2	-	27760321	HT29	viability after 10 days	AGGATTCCAGCGATGGAGCCGG	MSGN1	ENSG00000151379	-0.09788249258859444	[498,389]	[571,458,522]	-1	hSpCas9	negative selection	5337834
17816721	17816743	2	-	27760321	HT29	viability after 10 days	CTGGCCCCGCCGTGCTCACAGG	MSGN1	ENSG00000151379	-0.10922206852308747	[677,528]	[796,763,539]	-1	hSpCas9	negative selection	5337835
17816778	17816800	2	-	27760321	HT29	viability after 10 days	TCCACCTCTACCAGGCCACTGG	MSGN1	ENSG00000151379	0.8341384994309031	[747,583]	[1472,1441,1529]	9	hSpCas9	negative selection	5337836
17816826	17816848	2	-	27760321	HT29	viability after 10 days	CCACCACCGCCCTGAAGGTGGG	MSGN1	ENSG00000151379	0.8336746744225912	[682,532]	[1314,1078,1649]	9	hSpCas9	negative selection	5337837
17816621	17816643	2	-	27760321	MOLM13	viability	AGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	2.2232971382587263	[359,255]	[723,869]	9	hSpCas9	negative selection	5421296
17816663	17816685	2	-	27760321	MOLM13	viability	AGGATTCCAGCGATGGAGCCGG	MSGN1	ENSG00000151379	0.178457230692509	[510,498]	[461,204]	1	hSpCas9	negative selection	5421297
17816721	17816743	2	-	27760321	MOLM13	viability	CTGGCCCCGCCGTGCTCACAGG	MSGN1	ENSG00000151379	0.8854796440315104	[708,677]	[1229,292]	6	hSpCas9	negative selection	5421298
17816778	17816800	2	-	27760321	MOLM13	viability	TCCACCTCTACCAGGCCACTGG	MSGN1	ENSG00000151379	1.0539682765484217	[851,747]	[1214,696]	7	hSpCas9	negative selection	5421299
17816826	17816848	2	-	27760321	MOLM13	viability	CCACCACCGCCCTGAAGGTGGG	MSGN1	ENSG00000151379	0.275657527322703	[820,682]	[572,458]	1	hSpCas9	negative selection	5421300
17816877	17816900	2	+	27661255	K562	viability	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	-0.03051420604160715	[1209,1084]	[997,814]	-1	dCas9-KRAB	negative selection	5494396
17816892	17816915	2	+	27661255	K562	viability	GGAGGCGGAAAGCCAGCGAGAGG	MSGN1	ENSG00000151379	0.25303995892555275	[828,1004]	[877,862]	8	dCas9-KRAB	negative selection	5494397
17816661	17816684	2	-	27661255	K562	viability	GGATTCCAGCGATGGAGCCGGGG	MSGN1	ENSG00000151379	0.2840155855327768	[760,815]	[793,741]	8	dCas9-KRAB	negative selection	5494398
17817061	17817084	2	-	27260156	BXPC3	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.4945075627684403	[90]	[140,114,102,181]	9	hSpCas9	negative selection	5556304
17817030	17817053	2	-	27260156	BXPC3	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.6393443280098767	[80]	[134,111,147,132]	9	hSpCas9	negative selection	5556305
17816785	17816808	2	-	27260156	BXPC3	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	-0.076996512169897	[1835]	[1721,1721,1732,2144]	-2	hSpCas9	negative selection	5556306
17817088	17817111	2	-	27260156	BXPC3	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.2547230770381841	[307]	[229,241,376,231]	-5	hSpCas9	negative selection	5620562
17816947	17816970	2	-	27260156	BXPC3	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.3453260121354681	[386]	[309,274,283,417]	-6	hSpCas9	negative selection	5620563
17817050	17817073	2	+	27260156	BXPC3	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.33915207972242556	[502]	[771,545,642,693]	7	hSpCas9	negative selection	5620564
17817061	17817084	2	-	27260156	A673	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.4260179186662596	[90]	[120,99,165,200]	8	hSpCas9	negative selection	5677555
17817030	17817053	2	-	27260156	A673	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.25239922687580885	[80]	[191,114,72,90]	6	hSpCas9	negative selection	5677556
17816785	17816808	2	-	27260156	A673	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.03012680866596451	[1835]	[2389,2214,2168,2242]	0	hSpCas9	negative selection	5677557
17817088	17817111	2	-	27260156	A673	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.4419663284619473	[307]	[370,243,214,270]	-8	hSpCas9	negative selection	5741813
17816947	17816970	2	-	27260156	A673	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.2694195368114449	[386]	[415,351,430,343]	-6	hSpCas9	negative selection	5741814
17817050	17817073	2	+	27260156	A673	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.11205626806684175	[502]	[712,794,551,547]	2	hSpCas9	negative selection	5741815
17817061	17817084	2	-	27260156	A375	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.8995978948640255	[90]	[194,199,193,202]	9	hSpCas9	negative selection	5798806
17817030	17817053	2	-	27260156	A375	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.9158158396005942	[80]	[148,175,211,175]	9	hSpCas9	negative selection	5798807
17816785	17816808	2	-	27260156	A375	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.4119688368192522	[1835]	[3056,3227,2583,2614]	6	hSpCas9	negative selection	5798808
17817088	17817111	2	-	27260156	A375	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.032384717053702716	[307]	[420,340,476,242]	0	hSpCas9	negative selection	5863064
17816947	17816970	2	-	27260156	A375	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	0.05661065758505329	[386]	[441,519,588,348]	0	hSpCas9	negative selection	5863065
17817050	17817073	2	+	27260156	A375	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.4641405328107796	[502]	[819,787,977,666]	6	hSpCas9	negative selection	5863066
17817061	17817084	2	-	27260156	COLO741	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.8198344409770377	[90]	[268,96,250]	9	hSpCas9	negative selection	5920057
17817030	17817053	2	-	27260156	COLO741	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.6080954309845474	[80]	[145,210,117]	9	hSpCas9	negative selection	5920058
17816785	17816808	2	-	27260156	COLO741	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.02335494562163265	[1835]	[2503,2393,2267]	0	hSpCas9	negative selection	5920059
17817088	17817111	2	-	27260156	COLO741	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.3925201445371358	[307]	[293,356,250]	-7	hSpCas9	negative selection	5984315
17816947	17816970	2	-	27260156	COLO741	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.2299455944157488	[386]	[291,508,449]	-5	hSpCas9	negative selection	5984316
17817050	17817073	2	+	27260156	COLO741	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.12908450402411176	[502]	[711,696,698]	2	hSpCas9	negative selection	5984317
17817061	17817084	2	-	27260156	CAL120	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.9302374803352489	[90]	[228,133,284]	9	hSpCas9	negative selection	6041308
17817030	17817053	2	-	27260156	CAL120	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.17415832710066548	[80]	[75,119,138]	2	hSpCas9	negative selection	6041309
17816785	17816808	2	-	27260156	CAL120	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.2579770015803995	[1835]	[2836,2821,2554]	4	hSpCas9	negative selection	6041310
17817088	17817111	2	-	27260156	CAL120	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.11986422348329695	[307]	[185,498,347]	-2	hSpCas9	negative selection	6105566
17816947	17816970	2	-	27260156	CAL120	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	0.19980950771319178	[386]	[515,442,691]	3	hSpCas9	negative selection	6105567
17817050	17817073	2	+	27260156	CAL120	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.004823539132105689	[502]	[529,539,795]	0	hSpCas9	negative selection	6105568
17817061	17817084	2	-	27260156	CADOES1	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.1554847427370767	[90]	[81,106,96,90]	2	hSpCas9	negative selection	6162559
17817030	17817053	2	-	27260156	CADOES1	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.7827172572529555	[80]	[78,129,167,141]	9	hSpCas9	negative selection	6162560
17816785	17816808	2	-	27260156	CADOES1	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.268092552813769	[1835]	[2134,1764,2225,2099]	4	hSpCas9	negative selection	6162561
17817088	17817111	2	-	27260156	CADOES1	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.3468212754038387	[307]	[313,343,263,541]	6	hSpCas9	negative selection	6226817
17816947	17816970	2	-	27260156	CADOES1	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.17070289183188503	[386]	[375,235,365,299]	-3	hSpCas9	negative selection	6226818
17817050	17817073	2	+	27260156	CADOES1	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	-0.23816754923427907	[502]	[397,283,411,495]	-4	hSpCas9	negative selection	6226819
17817061	17817084	2	-	27260156	EWS502	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.8091808222007248	[90]	[105,77,215,295]	9	hSpCas9	negative selection	6283810
17817030	17817053	2	-	27260156	EWS502	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.1427146572518776	[80]	[52,104,108,117]	2	hSpCas9	negative selection	6283811
17816785	17816808	2	-	27260156	EWS502	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.037563414109802684	[1835]	[1973,2052,1900,2050]	0	hSpCas9	negative selection	6283812
17817088	17817111	2	-	27260156	EWS502	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.19744143107416007	[307]	[322,430,316,430]	3	hSpCas9	negative selection	6348068
17816947	17816970	2	-	27260156	EWS502	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.16471507074880387	[386]	[503,324,370,236]	-3	hSpCas9	negative selection	6348069
17817050	17817073	2	+	27260156	EWS502	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	-0.13279821122908342	[502]	[423,480,615,425]	-2	hSpCas9	negative selection	6348070
17817061	17817084	2	-	27260156	EW8	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	1.2415679863306917	[90]	[247,231,124,108]	9	hSpCas9	negative selection	6405061
17817030	17817053	2	-	27260156	EW8	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.1950683883409874	[80]	[111,67,83,38]	3	hSpCas9	negative selection	6405062
17816785	17816808	2	-	27260156	EW8	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.1338235308677993	[1835]	[2060,1756,1246,1573]	2	hSpCas9	negative selection	6405063
17817088	17817111	2	-	27260156	EW8	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.3245559615812902	[307]	[283,135,233,145]	-6	hSpCas9	negative selection	6469319
17816947	17816970	2	-	27260156	EW8	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.007735608946732697	[386]	[365,333,300,253]	0	hSpCas9	negative selection	6469320
17817050	17817073	2	+	27260156	EW8	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.2587111414976883	[502]	[742,466,403,377]	5	hSpCas9	negative selection	6469321
17817061	17817084	2	-	27260156	CORL105	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.8456875162380952	[90]	[121,208,198,233]	9	hSpCas9	negative selection	6526312
17817030	17817053	2	-	27260156	CORL105	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.1732442803395795	[80]	[83,100,138,107]	3	hSpCas9	negative selection	6526313
17816785	17816808	2	-	27260156	CORL105	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.02304343077799853	[1835]	[2240,2072,2414,2046]	0	hSpCas9	negative selection	6526314
17817088	17817111	2	-	27260156	CORL105	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.058562230962581285	[307]	[289,370,425,307]	-1	hSpCas9	negative selection	6590570
17816947	17816970	2	-	27260156	CORL105	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	0.006739303072049785	[386]	[433,437,548,413]	0	hSpCas9	negative selection	6590571
17817050	17817073	2	+	27260156	CORL105	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.023833685450263195	[502]	[517,625,617,631]	0	hSpCas9	negative selection	6590572
17817061	17817084	2	-	27260156	HS294T	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.5822831261051502	[90]	[81,44,37,40]	7	hSpCas9	negative selection	6647563
17817030	17817053	2	-	27260156	HS294T	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.20732446103154345	[80]	[58,33,24,21]	3	hSpCas9	negative selection	6647564
17816785	17816808	2	-	27260156	HS294T	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.22454282828681538	[1835]	[753,778,736,1098]	3	hSpCas9	negative selection	6647565
17817088	17817111	2	-	27260156	HS294T	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.4519169367628115	[307]	[133,58,70,78]	-6	hSpCas9	negative selection	6711821
17816947	17816970	2	-	27260156	HS294T	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.5487360240101288	[386]	[145,92,57,108]	-7	hSpCas9	negative selection	6711822
17817050	17817073	2	+	27260156	HS294T	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	-0.29316315053739794	[502]	[160,100,120,271]	-4	hSpCas9	negative selection	6711823
17817061	17817084	2	-	27260156	HCC44	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	1.0306138021623623	[90]	[183,102,292,283]	9	hSpCas9	negative selection	6768814
17817030	17817053	2	-	27260156	HCC44	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.46989082664143345	[80]	[141,38,203,147]	7	hSpCas9	negative selection	6768815
17816785	17816808	2	-	27260156	HCC44	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.2745743236969649	[1835]	[2926,2114,2981,2188]	4	hSpCas9	negative selection	6768816
17817088	17817111	2	-	27260156	HCC44	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.027635023975265183	[307]	[266,224,298,567]	0	hSpCas9	negative selection	6833072
17816947	17816970	2	-	27260156	HCC44	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.45398575749827497	[386]	[218,332,429,301]	-6	hSpCas9	negative selection	6833073
17817050	17817073	2	+	27260156	HCC44	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.23191851297354932	[502]	[735,425,1034,576]	4	hSpCas9	negative selection	6833074
17817061	17817084	2	-	27260156	G402	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	1.0556399103118415	[90]	[168,129,471,140]	9	hSpCas9	negative selection	6890065
17817030	17817053	2	-	27260156	G402	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	-0.12918242042447536	[80]	[85,22,165,81]	-2	hSpCas9	negative selection	6890066
17816785	17816808	2	-	27260156	G402	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.3411959240239282	[1835]	[2755,3581,2992,2078]	4	hSpCas9	negative selection	6890067
17817088	17817111	2	-	27260156	G402	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.3274234817618291	[307]	[327,354,237,283]	-4	hSpCas9	negative selection	6954323
17816947	17816970	2	-	27260156	G402	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.10416530391948281	[386]	[526,408,401,428]	-1	hSpCas9	negative selection	6954324
17817050	17817073	2	+	27260156	G402	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.2209067361388926	[502]	[931,702,494,756]	2	hSpCas9	negative selection	6954325
17817061	17817084	2	-	27260156	L33	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.4170548132909182	[90]	[116,46,95,101]	8	hSpCas9	negative selection	7011316
17817030	17817053	2	-	27260156	L33	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.4016671916758252	[80]	[84,36,70,139]	8	hSpCas9	negative selection	7011317
17816785	17816808	2	-	27260156	L33	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.055518601973215675	[1835]	[1988,831,1266,1597]	1	hSpCas9	negative selection	7011318
17817088	17817111	2	-	27260156	L33	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.48103179704416577	[307]	[228,69,110,304]	-8	hSpCas9	negative selection	7075574
17816947	17816970	2	-	27260156	L33	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.15527927987827567	[386]	[221,150,213,460]	-4	hSpCas9	negative selection	7075575
17817050	17817073	2	+	27260156	L33	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	-0.6826875231288926	[502]	[284,112,237,314]	-9	hSpCas9	negative selection	7075576
17817061	17817084	2	-	27260156	K562	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.8946660003510116	[90]	[181,197,149,82]	9	hSpCas9	negative selection	7132567
17817030	17817053	2	-	27260156	K562	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	-0.15636701852579726	[80]	[36,80,98,41]	-2	hSpCas9	negative selection	7132568
17816785	17816808	2	-	27260156	K562	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.28568507852720404	[1835]	[2076,2370,2230,1358]	3	hSpCas9	negative selection	7132569
17817088	17817111	2	-	27260156	K562	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.06996602241166006	[307]	[196,276,249,400]	0	hSpCas9	negative selection	7196825
17816947	17816970	2	-	27260156	K562	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.07654048598117047	[386]	[547,423,189,179]	-1	hSpCas9	negative selection	7196826
17817050	17817073	2	+	27260156	K562	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.4299459951652791	[502]	[344,932,790,358]	5	hSpCas9	negative selection	7196827
17817061	17817084	2	-	27260156	HT29	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.7842910923240369	[90]	[285,123,185,168]	9	hSpCas9	negative selection	7253818
17817030	17817053	2	-	27260156	HT29	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.3256365110872652	[80]	[204,118,45,127]	6	hSpCas9	negative selection	7253819
17816785	17816808	2	-	27260156	HT29	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.15375094591503813	[1835]	[2620,2517,2592,2226]	3	hSpCas9	negative selection	7253820
17817088	17817111	2	-	27260156	HT29	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.11001886497391722	[307]	[322,341,389,329]	-2	hSpCas9	negative selection	7318076
17816947	17816970	2	-	27260156	HT29	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.20436039301144954	[386]	[328,434,494,371]	-4	hSpCas9	negative selection	7318077
17817050	17817073	2	+	27260156	HT29	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.359272097914685	[502]	[850,826,915,572]	7	hSpCas9	negative selection	7318078
17817061	17817084	2	-	27260156	MHHES1	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.8675467815323332	[90]	[81,186,368,111]	9	hSpCas9	negative selection	7375069
17817030	17817053	2	-	27260156	MHHES1	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	-0.2567775905324612	[80]	[94,49,110,52]	-5	hSpCas9	negative selection	7375070
17816785	17816808	2	-	27260156	MHHES1	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.3533441487496669	[1835]	[3373,2784,2694,1924]	6	hSpCas9	negative selection	7375071
17817088	17817111	2	-	27260156	MHHES1	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.07422670145615096	[307]	[360,261,271,395]	-1	hSpCas9	negative selection	7439327
17816947	17816970	2	-	27260156	MHHES1	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.5946079910659385	[386]	[244,401,204,298]	-8	hSpCas9	negative selection	7439328
17817050	17817073	2	+	27260156	MHHES1	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.47083243197974156	[502]	[1052,784,742,613]	8	hSpCas9	negative selection	7439329
17817061	17817084	2	-	27260156	MEWO	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.8956140700695843	[90]	[150,95,226]	9	hSpCas9	negative selection	7496320
17817030	17817053	2	-	27260156	MEWO	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.5703974849775808	[80]	[124,107,106]	9	hSpCas9	negative selection	7496321
17816785	17816808	2	-	27260156	MEWO	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.1504860813529223	[1835]	[2160,1802,1804]	3	hSpCas9	negative selection	7496322
17817088	17817111	2	-	27260156	MEWO	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.37086242292844107	[307]	[199,228,234]	-7	hSpCas9	negative selection	7560578
17816947	17816970	2	-	27260156	MEWO	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.3397594425025793	[386]	[313,207,341]	-6	hSpCas9	negative selection	7560579
17817050	17817073	2	+	27260156	MEWO	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.0948707918444281	[502]	[559,652,304]	2	hSpCas9	negative selection	7560580
17817061	17817084	2	-	27260156	LNCAPCLONEFGC	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.6453670169093673	[90]	[99,64,226,142]	8	hSpCas9	negative selection	7617571
17817030	17817053	2	-	27260156	LNCAPCLONEFGC	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.7693233791083476	[80]	[95,86,183,144]	9	hSpCas9	negative selection	7617572
17816785	17816808	2	-	27260156	LNCAPCLONEFGC	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.29971620056774095	[1835]	[1852,1854,2580,1993]	5	hSpCas9	negative selection	7617573
17817088	17817111	2	-	27260156	LNCAPCLONEFGC	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.008627536942850234	[307]	[346,221,252,298]	0	hSpCas9	negative selection	7681829
17816947	17816970	2	-	27260156	LNCAPCLONEFGC	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.1312124282850879	[386]	[254,467,261,277]	-2	hSpCas9	negative selection	7681830
17817050	17817073	2	+	27260156	LNCAPCLONEFGC	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.22214213388705395	[502]	[703,368,672,407]	3	hSpCas9	negative selection	7681831
17817061	17817084	2	-	27260156	PANC0327	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.6544206824911809	[90]	[82,145,195,77]	8	hSpCas9	negative selection	7738822
17817030	17817053	2	-	27260156	PANC0327	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	1.5617577597512655	[80]	[159,232,371,77]	9	hSpCas9	negative selection	7738823
17816785	17816808	2	-	27260156	PANC0327	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.20316487125239768	[1835]	[2207,1737,1918,1689]	3	hSpCas9	negative selection	7738824
17817088	17817111	2	-	27260156	PANC0327	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.27917833593969	[307]	[258,298,177,158]	-4	hSpCas9	negative selection	7803080
17816947	17816970	2	-	27260156	PANC0327	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	0.0750992592618478	[386]	[502,377,332,243]	1	hSpCas9	negative selection	7803081
17817050	17817073	2	+	27260156	PANC0327	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.04842528222112512	[502]	[238,380,409,809]	0	hSpCas9	negative selection	7803082
17817061	17817084	2	-	27260156	NCIH2009	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	1.0985420594667867	[90]	[229,269,307]	9	hSpCas9	negative selection	7860073
17817030	17817053	2	-	27260156	NCIH2009	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.6092823488472425	[80]	[189,230,98]	8	hSpCas9	negative selection	7860074
17816785	17816808	2	-	27260156	NCIH2009	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.28407720589533114	[1835]	[3530,2824,3094]	4	hSpCas9	negative selection	7860075
17817088	17817111	2	-	27260156	NCIH2009	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.08122139620908897	[307]	[544,438,398]	1	hSpCas9	negative selection	7924331
17816947	17816970	2	-	27260156	NCIH2009	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.08062488678974306	[386]	[768,290,527]	-1	hSpCas9	negative selection	7924332
17817050	17817073	2	+	27260156	NCIH2009	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.08262708821873259	[502]	[786,676,776]	1	hSpCas9	negative selection	7924333
17817061	17817084	2	-	27260156	NCIH1373	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.9108139489348717	[90]	[327,96,122,66]	8	hSpCas9	negative selection	7981324
17817030	17817053	2	-	27260156	NCIH1373	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.44191274411602155	[80]	[40,87,128,60]	4	hSpCas9	negative selection	7981325
17816785	17816808	2	-	27260156	NCIH1373	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.3745406764181751	[1835]	[3620,2527,2322,613]	3	hSpCas9	negative selection	7981326
17817088	17817111	2	-	27260156	NCIH1373	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.19500681994300706	[307]	[414,274,347,46]	-2	hSpCas9	negative selection	8045582
17816947	17816970	2	-	27260156	NCIH1373	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	0.011823927230890985	[386]	[465,244,542,136]	0	hSpCas9	negative selection	8045583
17817050	17817073	2	+	27260156	NCIH1373	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.21427344781893104	[502]	[1043,352,486,219]	2	hSpCas9	negative selection	8045584
17817061	17817084	2	-	27260156	PATU8902	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	1.6352738009783419	[90]	[420,334,230,657]	9	hSpCas9	negative selection	8102575
17817030	17817053	2	-	27260156	PATU8902	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.9054838565479284	[80]	[11,94,342,381]	8	hSpCas9	negative selection	8102576
17816785	17816808	2	-	27260156	PATU8902	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.22707116732423605	[1835]	[2722,3113,2045,4493]	2	hSpCas9	negative selection	8102577
17817088	17817111	2	-	27260156	PATU8902	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.07381653183870396	[307]	[457,466,337,377]	0	hSpCas9	negative selection	8166833
17816947	17816970	2	-	27260156	PATU8902	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	0.3146900233576457	[386]	[785,771,473,696]	3	hSpCas9	negative selection	8166834
17817050	17817073	2	+	27260156	PATU8902	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.4809173130589973	[502]	[1112,933,803,1110]	5	hSpCas9	negative selection	8166835
17817061	17817084	2	-	27260156	PANC1	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.7059889163307052	[90]	[140,124,146,98]	9	hSpCas9	negative selection	8223826
17817030	17817053	2	-	27260156	PANC1	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.16310843748155746	[80]	[72,49,84,93]	2	hSpCas9	negative selection	8223827
17816785	17816808	2	-	27260156	PANC1	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.2574242666409441	[1835]	[1884,2159,1846,1702]	4	hSpCas9	negative selection	8223828
17817088	17817111	2	-	27260156	PANC1	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.02343992413474849	[307]	[254,291,233,290]	0	hSpCas9	negative selection	8288084
17816947	17816970	2	-	27260156	PANC1	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.22067812111495577	[386]	[160,422,242,331]	-4	hSpCas9	negative selection	8288085
17817050	17817073	2	+	27260156	PANC1	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.309069931653161	[502]	[552,674,599,361]	5	hSpCas9	negative selection	8288086
17817061	17817084	2	-	27260156	PANC0813	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.3953467779275466	[90]	[194,147,153,73]	6	hSpCas9	negative selection	8345077
17817030	17817053	2	-	27260156	PANC0813	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.3476025098345139	[80]	[125,130,132,95]	5	hSpCas9	negative selection	8345078
17816785	17816808	2	-	27260156	PANC0813	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.060731078362228574	[1835]	[2365,2222,2163,2250]	1	hSpCas9	negative selection	8345079
17817088	17817111	2	-	27260156	PANC0813	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.65900947243213	[307]	[355,245,126,199]	-7	hSpCas9	negative selection	8409335
17816947	17816970	2	-	27260156	PANC0813	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.15373606042521165	[386]	[461,312,453,409]	-3	hSpCas9	negative selection	8409336
17817050	17817073	2	+	27260156	PANC0813	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	-0.3767198985382565	[502]	[537,383,429,473]	-5	hSpCas9	negative selection	8409337
17817061	17817084	2	-	27260156	RDES	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.797380888222667	[90]	[152,184,140,258]	9	hSpCas9	negative selection	8466328
17817030	17817053	2	-	27260156	RDES	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.14235133483611717	[80]	[98,93,83,136]	2	hSpCas9	negative selection	8466329
17816785	17816808	2	-	27260156	RDES	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.2554294712629346	[1835]	[1803,2558,2866,3019]	4	hSpCas9	negative selection	8466330
17817088	17817111	2	-	27260156	RDES	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.11991027431029522	[307]	[336,401,323,485]	2	hSpCas9	negative selection	8530586
17816947	17816970	2	-	27260156	RDES	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.17218313377127853	[386]	[335,348,437,475]	-3	hSpCas9	negative selection	8530587
17817050	17817073	2	+	27260156	RDES	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.1309471420901347	[502]	[516,645,717,664]	2	hSpCas9	negative selection	8530588
17817061	17817084	2	-	27260156	PC3	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.11770923013222756	[90]	[26,102,287,74]	2	hSpCas9	negative selection	8587579
17817030	17817053	2	-	27260156	PC3	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.13007749047983674	[80]	[36,70,195,109]	3	hSpCas9	negative selection	8587580
17816785	17816808	2	-	27260156	PC3	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.05570450126959492	[1835]	[1230,2199,2778,1818]	1	hSpCas9	negative selection	8587581
17817088	17817111	2	-	27260156	PC3	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.4683992139381785	[307]	[154,175,432,213]	-8	hSpCas9	negative selection	8651837
17816947	17816970	2	-	27260156	PC3	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.5940605037231109	[386]	[183,250,398,246]	-8	hSpCas9	negative selection	8651838
17817050	17817073	2	+	27260156	PC3	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	-0.06432247353983432	[502]	[260,369,1202,425]	-1	hSpCas9	negative selection	8651839
17817061	17817084	2	-	27260156	PATU8988T	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.9689254046606006	[90]	[166,169,72,288]	9	hSpCas9	negative selection	8708830
17817030	17817053	2	-	27260156	PATU8988T	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.3052000935349515	[80]	[30,140,166,46]	5	hSpCas9	negative selection	8708831
17816785	17816808	2	-	27260156	PATU8988T	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.007707058451730919	[1835]	[1805,1770,1695,1867]	0	hSpCas9	negative selection	8708832
17817088	17817111	2	-	27260156	PATU8988T	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	0.03347822770602937	[307]	[226,332,436,214]	0	hSpCas9	negative selection	8773088
17816947	17816970	2	-	27260156	PATU8988T	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.13181203907499928	[386]	[354,351,361,292]	-2	hSpCas9	negative selection	8773089
17817050	17817073	2	+	27260156	PATU8988T	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.22086872410668745	[502]	[500,732,564,474]	4	hSpCas9	negative selection	8773090
17817061	17817084	2	-	27260156	T47D	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.7467013877362747	[90]	[155,199,205,145]	9	hSpCas9	negative selection	8830081
17817030	17817053	2	-	27260156	T47D	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.7297844495473644	[80]	[211,106,103,209]	9	hSpCas9	negative selection	8830082
17816785	17816808	2	-	27260156	T47D	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.11829868872450455	[1835]	[2363,2267,2226,2436]	2	hSpCas9	negative selection	8830083
17817088	17817111	2	-	27260156	T47D	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.1758094185226854	[307]	[397,237,296,345]	-4	hSpCas9	negative selection	8894339
17816947	17816970	2	-	27260156	T47D	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.31206215942559556	[386]	[451,305,382,314]	-6	hSpCas9	negative selection	8894340
17817050	17817073	2	+	27260156	T47D	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.07956354812386286	[502]	[646,653,670,496]	1	hSpCas9	negative selection	8894341
17817061	17817084	2	-	27260156	SU8686	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.8734582219419145	[90]	[174,120,164,210]	9	hSpCas9	negative selection	8951332
17817030	17817053	2	-	27260156	SU8686	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.312748381637618	[80]	[70,68,101,175]	5	hSpCas9	negative selection	8951333
17816785	17816808	2	-	27260156	SU8686	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.1001948704556932	[1835]	[1712,2083,1953,2067]	1	hSpCas9	negative selection	8951334
17817088	17817111	2	-	27260156	SU8686	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.3642792517964982	[307]	[143,257,288,270]	-6	hSpCas9	negative selection	9015590
17816947	17816970	2	-	27260156	SU8686	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.2520663958943191	[386]	[250,225,396,456]	-4	hSpCas9	negative selection	9015591
17817050	17817073	2	+	27260156	SU8686	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	-0.4695381658112673	[502]	[371,313,338,427]	-6	hSpCas9	negative selection	9015592
17817061	17817084	2	-	27260156	SKES1	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.20323730714740496	[90]	[93,89,109,117]	4	hSpCas9	negative selection	9072583
17817030	17817053	2	-	27260156	SKES1	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.013206841139317138	[80]	[59,104,107,54]	0	hSpCas9	negative selection	9072584
17816785	17816808	2	-	27260156	SKES1	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.14223100453120918	[1835]	[2148,2390,1802,1810]	3	hSpCas9	negative selection	9072585
17817088	17817111	2	-	27260156	SKES1	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.24031936021145606	[307]	[279,236,295,227]	-5	hSpCas9	negative selection	9136841
17816947	17816970	2	-	27260156	SKES1	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.40585356314330656	[386]	[349,309,297,222]	-7	hSpCas9	negative selection	9136842
17817050	17817073	2	+	27260156	SKES1	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.18895218840665795	[502]	[887,548,490,414]	4	hSpCas9	negative selection	9136843
17817061	17817084	2	-	27260156	TOV112D	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.5297477477292478	[90]	[55,234,115,137]	8	hSpCas9	negative selection	9193834
17817030	17817053	2	-	27260156	TOV112D	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	-0.23272953738006175	[80]	[25,108,68,77]	-4	hSpCas9	negative selection	9193835
17816785	17816808	2	-	27260156	TOV112D	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.24733910119577662	[1835]	[2091,2511,2458,1749]	5	hSpCas9	negative selection	9193836
17817088	17817111	2	-	27260156	TOV112D	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.2766605157613572	[307]	[150,254,220,378]	-5	hSpCas9	negative selection	9258092
17816947	17816970	2	-	27260156	TOV112D	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.4519664130479001	[386]	[414,266,246,212]	-7	hSpCas9	negative selection	9258093
17817050	17817073	2	+	27260156	TOV112D	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.31018540900680086	[502]	[647,723,531,619]	6	hSpCas9	negative selection	9258094
17817061	17817084	2	-	27260156	TC71	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	0.520580027010326	[90]	[83,142,164,169]	9	hSpCas9	negative selection	9315085
17817030	17817053	2	-	27260156	TC71	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.01422353321686387	[80]	[101,101,72,72]	0	hSpCas9	negative selection	9315086
17816785	17816808	2	-	27260156	TC71	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.0008005012140990253	[1835]	[1946,2006,1849,2083]	0	hSpCas9	negative selection	9315087
17817088	17817111	2	-	27260156	TC71	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.23757932386491387	[307]	[209,253,379,273]	-6	hSpCas9	negative selection	9379343
17816947	17816970	2	-	27260156	TC71	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	-0.575055656291914	[386]	[310,219,295,285]	-9	hSpCas9	negative selection	9379344
17817050	17817073	2	+	27260156	TC71	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.052285345846420014	[502]	[494,505,573,668]	1	hSpCas9	negative selection	9379345
17817061	17817084	2	-	27260156	TC32	viability	TGGGCTCTCTGCCGCGGTTAAGG	MSGN1	ENSG00000151379	1.1713364233521084	[90]	[169,118,173,331]	9	hSpCas9	negative selection	9436336
17817030	17817053	2	-	27260156	TC32	viability	GAGTTCCCCGATGTACTTGATGG	MSGN1	ENSG00000151379	0.6887471727895706	[80]	[101,111,165,116]	9	hSpCas9	negative selection	9436337
17816785	17816808	2	-	27260156	TC32	viability	TATTGTAGTCCACCTCTACCAGG	MSGN1	ENSG00000151379	0.22498944654525999	[1835]	[1967,1493,2498,2286]	4	hSpCas9	negative selection	9436338
17817088	17817111	2	-	27260156	TC32	viability	CGGATGGAGCTCACGCGCTCTGG	MSGN1	ENSG00000151379	-0.0376767003549322	[307]	[274,237,283,333]	0	hSpCas9	negative selection	9500594
17816947	17816970	2	-	27260156	TC32	viability	GGTAATTCCGGAGGGTGTGCAGG	MSGN1	ENSG00000151379	0.2455092860265865	[386]	[407,450,486,349]	4	hSpCas9	negative selection	9500595
17817050	17817073	2	+	27260156	TC32	viability	CTCACAGACCTCCTTAACCGCGG	MSGN1	ENSG00000151379	0.6213054792420177	[502]	[830,560,710,810]	9	hSpCas9	negative selection	9500596
17816500	17816523	2	+	27869803	HPAFII	viability after 27 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	-1.5588182118618628	[26]	[0,7,NaN]	-7	hSpCas9	negative selection	9572535
17816593	17816616	2	+	27869803	HPAFII	viability after 27 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	0.17843238725210678	[190]	[183,54,NaN]	1	hSpCas9	negative selection	9572536
17816621	17816644	2	-	27869803	HPAFII	viability after 27 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.7637098987959104	[126]	[96,126,NaN]	6	hSpCas9	negative selection	9572537
17816662	17816685	2	-	27869803	HPAFII	viability after 27 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	0.3781386700058115	[123]	[27,131,NaN]	3	hSpCas9	negative selection	9572538
17816877	17816900	2	+	27869803	HPAFII	viability after 27 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	1.037248368611959	[220]	[202,267,NaN]	8	hSpCas9	negative selection	9572539
17816500	17816523	2	+	27869803	HPAFII	viability after 15 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	0.31833762032416724	[26]	[21,44,NaN]	3	hSpCas9	negative selection	9654984
17816593	17816616	2	+	27869803	HPAFII	viability after 15 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.10290706343594824	[190]	[274,138,NaN]	-1	hSpCas9	negative selection	9654985
17816621	17816644	2	-	27869803	HPAFII	viability after 15 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.9408418588711388	[126]	[409,169,NaN]	9	hSpCas9	negative selection	9654986
17816662	17816685	2	-	27869803	HPAFII	viability after 15 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	0.6523194697393628	[123]	[251,182,NaN]	7	hSpCas9	negative selection	9654987
17816877	17816900	2	+	27869803	HPAFII	viability after 15 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	1.0250470609357116	[220]	[655,375,NaN]	9	hSpCas9	negative selection	9654988
17816500	17816523	2	+	27869803	ASPC1	viability after 36 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	2.5905230827714414	[68]	[0,0,358]	9	hSpCas9	negative selection	9737433
17816593	17816616	2	+	27869803	ASPC1	viability after 36 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	0.36632664318871716	[406]	[106,256,175]	3	hSpCas9	negative selection	9737434
17816621	17816644	2	-	27869803	ASPC1	viability after 36 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.10002969822971386	[304]	[267,74,35]	1	hSpCas9	negative selection	9737435
17816662	17816685	2	-	27869803	ASPC1	viability after 36 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	0.920670353451991	[339]	[271,380,64]	8	hSpCas9	negative selection	9737436
17816877	17816900	2	+	27869803	ASPC1	viability after 36 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.8420785564777831	[648]	[514,184,500]	7	hSpCas9	negative selection	9737437
17816500	17816523	2	+	27869803	PATU8988S	viability after 35 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	0.12346652977815253	[80]	[51,18,NaN]	1	hSpCas9	negative selection	9819882
17816593	17816616	2	+	27869803	PATU8988S	viability after 35 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-1.075815396566782	[515]	[137,58,NaN]	-7	hSpCas9	negative selection	9819883
17816621	17816644	2	-	27869803	PATU8988S	viability after 35 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	-0.11223731306232287	[250]	[103,82,NaN]	-1	hSpCas9	negative selection	9819884
17816662	17816685	2	-	27869803	PATU8988S	viability after 35 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	1.2665866599676485	[257]	[248,250,NaN]	9	hSpCas9	negative selection	9819885
17816877	17816900	2	+	27869803	PATU8988S	viability after 35 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.5618350967465618	[604]	[439,278,NaN]	6	hSpCas9	negative selection	9819886
17816500	17816523	2	+	27869803	PATU8988S	viability after 31 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	-0.2668799155474266	[80]	[43,4,NaN]	-3	hSpCas9	negative selection	9902331
17816593	17816616	2	+	27869803	PATU8988S	viability after 31 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.7329401254642878	[515]	[103,148,NaN]	-7	hSpCas9	negative selection	9902332
17816621	17816644	2	-	27869803	PATU8988S	viability after 31 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	-1.2094840507976192	[250]	[37,49,NaN]	-8	hSpCas9	negative selection	9902333
17816662	17816685	2	-	27869803	PATU8988S	viability after 31 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	1.1973700024985994	[257]	[216,259,NaN]	9	hSpCas9	negative selection	9902334
17816877	17816900	2	+	27869803	PATU8988S	viability after 31 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	0.9019992450675371	[604]	[419,489,NaN]	8	hSpCas9	negative selection	9902335
17816500	17816523	2	+	27869803	HPAFII	viability after 35 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	-0.9420113326440669	[26]	[0,13,NaN]	-5	hSpCas9	negative selection	9984780
17816593	17816616	2	+	27869803	HPAFII	viability after 35 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.314037872306937	[190]	[105,45,NaN]	-2	hSpCas9	negative selection	9984781
17816621	17816644	2	-	27869803	HPAFII	viability after 35 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.897868924427875	[126]	[68,176,NaN]	6	hSpCas9	negative selection	9984782
17816662	17816685	2	-	27869803	HPAFII	viability after 35 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	0.44157033808087276	[123]	[1,178,NaN]	3	hSpCas9	negative selection	9984783
17816877	17816900	2	+	27869803	HPAFII	viability after 35 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	1.4660365079497881	[220]	[238,387,NaN]	8	hSpCas9	negative selection	9984784
17816500	17816523	2	+	27869803	HPAFII	viability after 31 days	CTGCAGCTGTCTCGCAGGCATGG	MSGN1	ENSG00000151379	1.3207050926101587	[26]	[0,77,NaN]	8	hSpCas9	negative selection	10067229
17816593	17816616	2	+	27869803	HPAFII	viability after 31 days	TTCCTGGGACTGGAAGGACAGGG	MSGN1	ENSG00000151379	-0.08696890525712658	[190]	[154,41,NaN]	0	hSpCas9	negative selection	10067230
17816621	17816644	2	-	27869803	HPAFII	viability after 31 days	GAGGCCTGATTCAGCTCAAAGGG	MSGN1	ENSG00000151379	0.9002013724910642	[126]	[99,168,NaN]	6	hSpCas9	negative selection	10067231
17816662	17816685	2	-	27869803	HPAFII	viability after 31 days	AGGATTCCAGCGATGGAGCCGGG	MSGN1	ENSG00000151379	-0.0017357727353315422	[123]	[24,117,NaN]	0	hSpCas9	negative selection	10067232
17816877	17816900	2	+	27869803	HPAFII	viability after 31 days	GGATGTCTGTCCAGCGGAGGCGG	MSGN1	ENSG00000151379	1.2894586277609348	[220]	[172,444,NaN]	8	hSpCas9	negative selection	10067233
17816669	17816692	2	-	28162770	P31FUJ	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	-0.2097185913013373	[61]	[62]	-2	hSpCas9	negative selection	10194915
17816645	17816668	2	-	28162770	P31FUJ	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-1.3300994057692934	[183]	[85]	-7	hSpCas9	negative selection	10194916
17816714	17816737	2	+	28162770	P31FUJ	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	-1.1173249869944426	[47]	[25]	-7	hSpCas9	negative selection	10194917
17816819	17816842	2	+	28162770	P31FUJ	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	0.4489578877283731	[292]	[469]	5	hSpCas9	negative selection	10194918
17816874	17816897	2	+	28162770	P31FUJ	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	-0.6294069855962371	[336]	[255]	-5	hSpCas9	negative selection	10194919
17816934	17816957	2	-	28162770	P31FUJ	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	0.7613687167834239	[123]	[246]	8	hSpCas9	negative selection	10194920
17816956	17816979	2	-	28162770	P31FUJ	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	0.53198133389159	[225]	[383]	6	hSpCas9	negative selection	10194921
17817025	17817048	2	+	28162770	P31FUJ	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	0.23534663132402767	[179]	[248]	2	hSpCas9	negative selection	10194922
17817067	17817090	2	-	28162770	P31FUJ	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	-0.3978614506848749	[184]	[164]	-4	hSpCas9	negative selection	10194923
17816527	17816550	2	-	28162770	P31FUJ	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	0.2570030632664375	[46]	[65]	2	hSpCas9	negative selection	10194924
17816669	17816692	2	-	28162770	TF1	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10364281
17816645	17816668	2	-	28162770	TF1	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10364282
17816714	17816737	2	+	28162770	TF1	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10364283
17816819	17816842	2	+	28162770	TF1	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10364284
17816874	17816897	2	+	28162770	TF1	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	NaN	[NaN]	[169]	1	hSpCas9	negative selection	10364285
17816934	17816957	2	-	28162770	TF1	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10364286
17816956	17816979	2	-	28162770	TF1	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10364287
17817025	17817048	2	+	28162770	TF1	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	NaN	[NaN]	[149]	1	hSpCas9	negative selection	10364288
17817067	17817090	2	-	28162770	TF1	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	NaN	[NaN]	[56]	1	hSpCas9	negative selection	10364289
17816527	17816550	2	-	28162770	TF1	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	NaN	[NaN]	[25]	1	hSpCas9	negative selection	10364290
17816669	17816692	2	-	28162770	SKM1	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	-0.45276788835628623	[23]	[30]	-4	hSpCas9	negative selection	10533647
17816645	17816668	2	-	28162770	SKM1	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-1.732734359924918	[46]	[24]	-8	hSpCas9	negative selection	10533648
17816714	17816737	2	+	28162770	SKM1	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	-0.03350580321571739	[10]	[18]	0	hSpCas9	negative selection	10533649
17816819	17816842	2	+	28162770	SKM1	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	0.07846262842708018	[74]	[139]	0	hSpCas9	negative selection	10533650
17816874	17816897	2	+	28162770	SKM1	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	0.10535300014622861	[111]	[212]	1	hSpCas9	negative selection	10533651
17816934	17816957	2	-	28162770	SKM1	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	-0.9960310977970546	[43]	[38]	-6	hSpCas9	negative selection	10533652
17816956	17816979	2	-	28162770	SKM1	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	1.2184125704239026	[43]	[180]	9	hSpCas9	negative selection	10533653
17817025	17817048	2	+	28162770	SKM1	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	0.4099450300276911	[42]	[100]	4	hSpCas9	negative selection	10533654
17817067	17817090	2	-	28162770	SKM1	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	-0.009628701197776701	[40]	[71]	0	hSpCas9	negative selection	10533655
17816527	17816550	2	-	28162770	SKM1	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	0.2775339755289088	[6]	[14]	2	hSpCas9	negative selection	10533656
17816669	17816692	2	-	28162770	SKM1	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	-0.45276788835628623	[23]	[30]	-4	hSpCas9	negative selection	10703013
17816645	17816668	2	-	28162770	SKM1	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-1.732734359924918	[46]	[24]	-8	hSpCas9	negative selection	10703014
17816714	17816737	2	+	28162770	SKM1	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	-0.03350580321571739	[10]	[18]	0	hSpCas9	negative selection	10703015
17816819	17816842	2	+	28162770	SKM1	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	0.07846262842708018	[74]	[139]	0	hSpCas9	negative selection	10703016
17816874	17816897	2	+	28162770	SKM1	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	0.10535300014622861	[111]	[212]	1	hSpCas9	negative selection	10703017
17816934	17816957	2	-	28162770	SKM1	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	-0.9960310977970546	[43]	[38]	-6	hSpCas9	negative selection	10703018
17816956	17816979	2	-	28162770	SKM1	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	1.2184125704239026	[43]	[180]	9	hSpCas9	negative selection	10703019
17817025	17817048	2	+	28162770	SKM1	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	0.4099450300276911	[42]	[100]	4	hSpCas9	negative selection	10703020
17817067	17817090	2	-	28162770	SKM1	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	-0.009628701197776701	[40]	[71]	0	hSpCas9	negative selection	10703021
17816527	17816550	2	-	28162770	SKM1	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	0.2775339755289088	[6]	[14]	2	hSpCas9	negative selection	10703022
17816669	17816692	2	-	28162770	PL21	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	0.4576358367816842	[86]	[51]	4	hSpCas9	negative selection	10872379
17816645	17816668	2	-	28162770	PL21	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-1.0336575701193769	[126]	[26]	-6	hSpCas9	negative selection	10872380
17816714	17816737	2	+	28162770	PL21	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	-4.192177808289441	[41]	[0]	-9	hSpCas9	negative selection	10872381
17816819	17816842	2	+	28162770	PL21	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	0.5678713989898072	[247]	[159]	5	hSpCas9	negative selection	10872382
17816874	17816897	2	+	28162770	PL21	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	-0.2620798215195965	[258]	[93]	-2	hSpCas9	negative selection	10872383
17816934	17816957	2	-	28162770	PL21	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	-0.44371657528540465	[174]	[55]	-3	hSpCas9	negative selection	10872384
17816956	17816979	2	-	28162770	PL21	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	0.16407035978179835	[161]	[78]	1	hSpCas9	negative selection	10872385
17817025	17817048	2	+	28162770	PL21	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	-1.1921778082894403	[167]	[31]	-7	hSpCas9	negative selection	10872386
17817067	17817090	2	-	28162770	PL21	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	0.13712981696351945	[116]	[55]	1	hSpCas9	negative selection	10872387
17816527	17816550	2	-	28162770	PL21	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	-0.4569726719876712	[40]	[12]	-3	hSpCas9	negative selection	10872388
17816669	17816692	2	-	28162770	P31FUJ	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	-0.2097185913013373	[61]	[62]	-2	hSpCas9	negative selection	11041745
17816645	17816668	2	-	28162770	P31FUJ	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-1.3300994057692934	[183]	[85]	-7	hSpCas9	negative selection	11041746
17816714	17816737	2	+	28162770	P31FUJ	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	-1.1173249869944426	[47]	[25]	-7	hSpCas9	negative selection	11041747
17816819	17816842	2	+	28162770	P31FUJ	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	0.4489578877283731	[292]	[469]	5	hSpCas9	negative selection	11041748
17816874	17816897	2	+	28162770	P31FUJ	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	-0.6294069855962371	[336]	[255]	-5	hSpCas9	negative selection	11041749
17816934	17816957	2	-	28162770	P31FUJ	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	0.7613687167834239	[123]	[246]	8	hSpCas9	negative selection	11041750
17816956	17816979	2	-	28162770	P31FUJ	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	0.53198133389159	[225]	[383]	6	hSpCas9	negative selection	11041751
17817025	17817048	2	+	28162770	P31FUJ	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	0.23534663132402767	[179]	[248]	2	hSpCas9	negative selection	11041752
17817067	17817090	2	-	28162770	P31FUJ	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	-0.3978614506848749	[184]	[164]	-4	hSpCas9	negative selection	11041753
17816527	17816550	2	-	28162770	P31FUJ	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	0.2570030632664375	[46]	[65]	2	hSpCas9	negative selection	11041754
17816669	17816692	2	-	28162770	OCIAML5	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	1.2772164460809694	[15]	[69]	9	hSpCas9	negative selection	11211111
17816645	17816668	2	-	28162770	OCIAML5	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-1.7936498846386748	[120]	[62]	-7	hSpCas9	negative selection	11211112
17816714	17816737	2	+	28162770	OCIAML5	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	-1.2827009251938593	[30]	[22]	-6	hSpCas9	negative selection	11211113
17816819	17816842	2	+	28162770	OCIAML5	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	0.10671076640949018	[141]	[275]	0	hSpCas9	negative selection	11211114
17816874	17816897	2	+	28162770	OCIAML5	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	0.15890454695700615	[130]	[263]	1	hSpCas9	negative selection	11211115
17816934	17816957	2	-	28162770	OCIAML5	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	0.5036951190992407	[58]	[150]	4	hSpCas9	negative selection	11211116
17816956	17816979	2	-	28162770	OCIAML5	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	-0.018716440273448376	[109]	[195]	0	hSpCas9	negative selection	11211117
17817025	17817048	2	+	28162770	OCIAML5	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	-0.3451065821441137	[170]	[242]	-2	hSpCas9	negative selection	11211118
17817067	17817090	2	-	28162770	OCIAML5	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	0.2873364858014194	[68]	[151]	2	hSpCas9	negative selection	11211119
17816527	17816550	2	-	28162770	OCIAML5	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	-0.2671040701428411	[15]	[23]	-2	hSpCas9	negative selection	11211120
17816669	17816692	2	-	28162770	EOL1	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	0.788226300357754	[121]	[110]	7	hSpCas9	negative selection	11380477
17816645	17816668	2	-	28162770	EOL1	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-2.0596849125711487	[181]	[22]	-8	hSpCas9	negative selection	11380478
17816714	17816737	2	+	28162770	EOL1	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	-2.245377229871778	[80]	[8]	-8	hSpCas9	negative selection	11380479
17816819	17816842	2	+	28162770	EOL1	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	-0.1989667649148197	[389]	[178]	-1	hSpCas9	negative selection	11380480
17816874	17816897	2	+	28162770	EOL1	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	0.5225573424521941	[476]	[360]	5	hSpCas9	negative selection	11380481
17816934	17816957	2	-	28162770	EOL1	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	0.48001897558229123	[312]	[229]	4	hSpCas9	negative selection	11380482
17816956	17816979	2	-	28162770	EOL1	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	0.8036229893109281	[198]	[182]	7	hSpCas9	negative selection	11380483
17817025	17817048	2	+	28162770	EOL1	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	0.5095102722916908	[179]	[134]	4	hSpCas9	negative selection	11380484
17817067	17817090	2	-	28162770	EOL1	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	1.0636118093080864	[167]	[184]	8	hSpCas9	negative selection	11380485
17816527	17816550	2	-	28162770	EOL1	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	1.668708867140945	[39]	[66]	9	hSpCas9	negative selection	11380486
17816669	17816692	2	-	28162770	MOLM13	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	0.35997404237769115	[110]	[102]	2	hSpCas9	negative selection	11549843
17816645	17816668	2	-	28162770	MOLM13	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-5.1170731191765775	[191]	[3]	-9	hSpCas9	negative selection	11549844
17816714	17816737	2	+	28162770	MOLM13	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	-1.201962016763091	[34]	[10]	-6	hSpCas9	negative selection	11549845
17816819	17816842	2	+	28162770	MOLM13	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	0.19392541555252574	[317]	[262]	1	hSpCas9	negative selection	11549846
17816874	17816897	2	+	28162770	MOLM13	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	0.8396691637074649	[346]	[448]	6	hSpCas9	negative selection	11549847
17816934	17816957	2	-	28162770	MOLM13	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	-0.6544461613794734	[245]	[112]	-4	hSpCas9	negative selection	11549848
17816956	17816979	2	-	28162770	MOLM13	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	0.41649022903793453	[199]	[192]	3	hSpCas9	negative selection	11549849
17817025	17817048	2	+	28162770	MOLM13	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	-0.7361683048168794	[416]	[180]	-4	hSpCas9	negative selection	11549850
17817067	17817090	2	-	28162770	MOLM13	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	-0.034610958984604534	[152]	[107]	0	hSpCas9	negative selection	11549851
17816527	17816550	2	-	28162770	MOLM13	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	0.05980464290750187	[68]	[51]	0	hSpCas9	negative selection	11549852
17816669	17816692	2	-	28162770	HEL	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	2.9043240211970813	[82]	[397]	9	hSpCas9	negative selection	11719209
17816645	17816668	2	-	28162770	HEL	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-5.5002191218416865	[211]	[2]	-9	hSpCas9	negative selection	11719210
17816714	17816737	2	+	28162770	HEL	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	0.27708935968367654	[66]	[51]	2	hSpCas9	negative selection	11719211
17816819	17816842	2	+	28162770	HEL	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	0.6733890448405417	[325]	[332]	6	hSpCas9	negative selection	11719212
17816874	17816897	2	+	28162770	HEL	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	0.7058668105658213	[312]	[326]	6	hSpCas9	negative selection	11719213
17816934	17816957	2	-	28162770	HEL	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	-0.19889557233105354	[180]	[100]	-1	hSpCas9	negative selection	11719214
17816956	17816979	2	-	28162770	HEL	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	0.24820698815615472	[162]	[123]	2	hSpCas9	negative selection	11719215
17817025	17817048	2	+	28162770	HEL	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	-2.1931852422540183	[356]	[49]	-8	hSpCas9	negative selection	11719216
17817067	17817090	2	-	28162770	HEL	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	-0.17060652789962988	[180]	[102]	-1	hSpCas9	negative selection	11719217
17816527	17816550	2	-	28162770	HEL	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	-0.6942961552772142	[47]	[18]	-4	hSpCas9	negative selection	11719218
17816669	17816692	2	-	28162770	MV411	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	0.9425829692543546	[41]	[67]	8	hSpCas9	negative selection	11888575
17816645	17816668	2	-	28162770	MV411	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-1.7525624492172245	[167]	[41]	-8	hSpCas9	negative selection	11888576
17816714	17816737	2	+	28162770	MV411	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	0.9844031449489816	[14]	[24]	8	hSpCas9	negative selection	11888577
17816819	17816842	2	+	28162770	MV411	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	-0.06124796732373455	[243]	[196]	0	hSpCas9	negative selection	11888578
17816874	17816897	2	+	28162770	MV411	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	-0.27152739116414065	[234]	[163]	-2	hSpCas9	negative selection	11888579
17816934	17816957	2	-	28162770	MV411	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	-0.611863586307483	[204]	[112]	-4	hSpCas9	negative selection	11888580
17816956	17816979	2	-	28162770	MV411	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	0.45130988414842527	[111]	[128]	4	hSpCas9	negative selection	11888581
17817025	17817048	2	+	28162770	MV411	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	-0.6656849985372577	[144]	[76]	-5	hSpCas9	negative selection	11888582
17817067	17817090	2	-	28162770	MV411	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	0.2227754965485063	[117]	[115]	2	hSpCas9	negative selection	11888583
17816527	17816550	2	-	28162770	MV411	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	2.716922834083996	[12]	[71]	9	hSpCas9	negative selection	11888584
17816669	17816692	2	-	28162770	MONOMAC1	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	0.7276750256362091	[58]	[111]	7	hSpCas9	negative selection	12057941
17816645	17816668	2	-	28162770	MONOMAC1	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-1.9519243492230225	[80]	[23]	-8	hSpCas9	negative selection	12057942
17816714	17816737	2	+	28162770	MONOMAC1	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	-1.071505964975695	[21]	[11]	-7	hSpCas9	negative selection	12057943
17816819	17816842	2	+	28162770	MONOMAC1	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	0.27191754569625026	[150]	[208]	2	hSpCas9	negative selection	12057944
17816874	17816897	2	+	28162770	MONOMAC1	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	-0.19703684705955354	[159]	[159]	-2	hSpCas9	negative selection	12057945
17816934	17816957	2	-	28162770	MONOMAC1	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	-0.7116100198893118	[109]	[76]	-5	hSpCas9	negative selection	12057946
17816956	17816979	2	-	28162770	MONOMAC1	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	0.6598382108418492	[89]	[162]	6	hSpCas9	negative selection	12057947
17817025	17817048	2	+	28162770	MONOMAC1	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	-0.05953332330961869	[89]	[98]	0	hSpCas9	negative selection	12057948
17817067	17817090	2	-	28162770	MONOMAC1	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	0.6168118370835508	[94]	[166]	6	hSpCas9	negative selection	12057949
17816527	17816550	2	-	28162770	MONOMAC1	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	0.5191701869398551	[27]	[45]	5	hSpCas9	negative selection	12057950
17816669	17816692	2	-	28162770	OCIAML2	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	1.6252945947563744	[9]	[170]	9	hSpCas9	negative selection	12227307
17816645	17816668	2	-	28162770	OCIAML2	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-2.87116775482589	[32]	[24]	-9	hSpCas9	negative selection	12227308
17816714	17816737	2	+	28162770	OCIAML2	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	0.38735116988541085	[7]	[57]	4	hSpCas9	negative selection	12227309
17816819	17816842	2	+	28162770	OCIAML2	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	0.18612335854700512	[48]	[308]	1	hSpCas9	negative selection	12227310
17816874	17816897	2	+	28162770	OCIAML2	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	-0.06537334675590288	[36]	[195]	0	hSpCas9	negative selection	12227311
17816934	17816957	2	-	28162770	OCIAML2	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	0.5482292020091546	[37]	[307]	5	hSpCas9	negative selection	12227312
17816956	17816979	2	-	28162770	OCIAML2	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	0.5371896792171381	[22]	[184]	5	hSpCas9	negative selection	12227313
17817025	17817048	2	+	28162770	OCIAML2	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	0.19233518748026798	[26]	[170]	1	hSpCas9	negative selection	12227314
17817067	17817090	2	-	28162770	OCIAML2	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	0.14408001887304694	[23]	[146]	1	hSpCas9	negative selection	12227315
17816527	17816550	2	-	28162770	OCIAML2	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	-2.470629825242161	[9]	[9]	-8	hSpCas9	negative selection	12227316
17816669	17816692	2	-	28162770	OCIAML3	viability	GAAGAATAGGATTCCAGCGATGG	MSGN1	ENSG00000151379	0.33199177823206005	[14]	[56]	3	hSpCas9	negative selection	12396673
17816645	17816668	2	-	28162770	OCIAML3	viability	GCCGGGGAAAGGCTCTGAGAGGG	MSGN1	ENSG00000151379	-1.1868322588182898	[45]	[60]	-7	hSpCas9	negative selection	12396674
17816714	17816737	2	+	28162770	OCIAML3	viability	GGGCTGCCCTGTGAGCACGGCGG	MSGN1	ENSG00000151379	0.9503128758996473	[5]	[34]	8	hSpCas9	negative selection	12396675
17816819	17816842	2	+	28162770	OCIAML3	viability	CAGCCCACCCACCTTCAGGGCGG	MSGN1	ENSG00000151379	0.777961137062795	[67]	[351]	7	hSpCas9	negative selection	12396676
17816874	17816897	2	+	28162770	OCIAML3	viability	TCAGGATGTCTGTCCAGCGGAGG	MSGN1	ENSG00000151379	-0.07577125340382021	[58]	[168]	0	hSpCas9	negative selection	12396677
17816934	17816957	2	-	28162770	OCIAML3	viability	GGTGTGCAGGGCATCTGCCAAGG	MSGN1	ENSG00000151379	0.5090858526399403	[53]	[231]	5	hSpCas9	negative selection	12396678
17816956	17816979	2	-	28162770	OCIAML3	viability	CAGGTGGCAGGTAATTCCGGAGG	MSGN1	ENSG00000151379	-0.3291799526673184	[66]	[160]	-3	hSpCas9	negative selection	12396679
17817025	17817048	2	+	28162770	OCIAML3	viability	GTACACCATCAAGTACATCGGGG	MSGN1	ENSG00000151379	-0.6958872543433765	[65]	[122]	-5	hSpCas9	negative selection	12396680
17817067	17817090	2	-	28162770	OCIAML3	viability	GGGCTCTGGGCTCTCTGCCGCGG	MSGN1	ENSG00000151379	-0.9021299356864949	[25]	[41]	-6	hSpCas9	negative selection	12396681
17816527	17816550	2	-	28162770	OCIAML3	viability	GGCTGAGGAAAGTCTCGCGCAGG	MSGN1	ENSG00000151379	-2.594007640324163	[13]	[6]	-9	hSpCas9	negative selection	12396682