Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 4853
• Symbol: NOTCH2
• Description: notch receptor 2

DataSource: http://genomecrispr.dkfz.de/#!/results/NOTCH2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
119925702	119925725	1	+	26472758	Jiyoye	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-3.236680808268851	[124]	[9]	-9	hSpCas9	negative selection	110213
119925776	119925799	1	-	26472758	Jiyoye	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.6338518867541814	[213]	[103]	-4	hSpCas9	negative selection	110214
119925567	119925590	1	+	26472758	Jiyoye	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	-0.002808890046684942	[379]	[285]	0	hSpCas9	negative selection	110215
119920279	119920302	1	+	26472758	Jiyoye	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-0.8254853752844014	[46]	[19]	-5	hSpCas9	negative selection	110216
119969569	119969592	1	+	26472758	Jiyoye	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	-0.5284340312241717	[240]	[125]	-4	hSpCas9	negative selection	110217
119940693	119940716	1	+	26472758	Jiyoye	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	3.4071753815058736	[9]	[79]	9	hSpCas9	negative selection	110218
119937846	119937869	1	+	26472758	Jiyoye	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	-0.40779272466160565	[189]	[107]	-3	hSpCas9	negative selection	110219
119937369	119937392	1	+	26472758	Jiyoye	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	0.17516787129270428	[275]	[234]	1	hSpCas9	negative selection	110220
119929152	119929175	1	-	26472758	Jiyoye	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	0.8477479728918547	[27]	[37]	6	hSpCas9	negative selection	110221
119926554	119926577	1	-	26472758	Jiyoye	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	1.2528472351145796	[68]	[123]	7	hSpCas9	negative selection	110222
120005514	120005537	1	-	26472758	Jiyoye	viability	AAGAACCGCTGCCAGAATGGTGG	NOTCH2	ENSG00000134250	-0.2481764471066807	[188]	[119]	-2	hSpCas9	negative selection	110224
119997247	119997270	1	+	26472758	Jiyoye	viability	GGAGAACTGGTTGGCCACAGTGG	NOTCH2	ENSG00000134250	-0.007862117772970745	[27]	[20]	0	hSpCas9	negative selection	110234
119925702	119925725	1	+	26472758	KBM7	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-3.140162636462145	[368,274]	[16,16]	-9	hSpCas9	negative selection	301331
119925776	119925799	1	-	26472758	KBM7	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.7519178588539891	[703,622]	[118,243]	-6	hSpCas9	negative selection	301332
119925567	119925590	1	+	26472758	KBM7	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	0.5934485125911564	[1351,1116]	[1002,753]	6	hSpCas9	negative selection	301333
119920279	119920302	1	+	26472758	KBM7	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-2.0159101377233593	[535,332]	[57,41]	-8	hSpCas9	negative selection	301334
119969569	119969592	1	+	26472758	KBM7	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.4680032403868632	[725,459]	[544,229]	5	hSpCas9	negative selection	301335
119940693	119940716	1	+	26472758	KBM7	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	-0.15929429667676387	[399,257]	[142,129]	-1	hSpCas9	negative selection	301336
119937846	119937869	1	+	26472758	KBM7	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	-0.22440691415513803	[695,546]	[176,311]	-2	hSpCas9	negative selection	301337
119937369	119937392	1	+	26472758	KBM7	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	0.5104338326950002	[825,670]	[555,446]	5	hSpCas9	negative selection	301338
119929152	119929175	1	-	26472758	KBM7	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	0.2073689778044916	[163,75]	[90,37]	2	hSpCas9	negative selection	301339
119926554	119926577	1	-	26472758	KBM7	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	0.36507308935164584	[809,814]	[511,478]	4	hSpCas9	negative selection	301340
120005514	120005537	1	-	26472758	KBM7	viability	AAGAACCGCTGCCAGAATGGTGG	NOTCH2	ENSG00000134250	-1.6415065488702667	[899,1083]	[214,94]	-8	hSpCas9	negative selection	301342
119997247	119997270	1	+	26472758	KBM7	viability	GGAGAACTGGTTGGCCACAGTGG	NOTCH2	ENSG00000134250	-1.3592991866414923	[154,113]	[35,13]	-7	hSpCas9	negative selection	301352
119925702	119925725	1	+	26472758	Raji	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-2.7605129286190557	[145]	[4]	-9	hSpCas9	negative selection	492449
119925776	119925799	1	-	26472758	Raji	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.4001002126698393	[289]	[50]	-3	hSpCas9	negative selection	492450
119925567	119925590	1	+	26472758	Raji	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	-0.09108800566776232	[637]	[138]	-1	hSpCas9	negative selection	492451
119920279	119920302	1	+	26472758	Raji	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-1.9941544910884628	[205]	[11]	-8	hSpCas9	negative selection	492452
119969569	119969592	1	+	26472758	Raji	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.24940254024602754	[289]	[79]	2	hSpCas9	negative selection	492453
119940693	119940716	1	+	26472758	Raji	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	0.15629313585454563	[115]	[29]	1	hSpCas9	negative selection	492454
119937846	119937869	1	+	26472758	Raji	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	0.3953642983376242	[343]	[104]	4	hSpCas9	negative selection	492455
119937369	119937392	1	+	26472758	Raji	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	0.7561219465280704	[471]	[184]	7	hSpCas9	negative selection	492456
119929152	119929175	1	-	26472758	Raji	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	0.2379676451837438	[94]	[25]	2	hSpCas9	negative selection	492457
119926554	119926577	1	-	26472758	Raji	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	0.6912193706404715	[426]	[159]	6	hSpCas9	negative selection	492458
120005514	120005537	1	-	26472758	Raji	viability	AAGAACCGCTGCCAGAATGGTGG	NOTCH2	ENSG00000134250	-1.1723647440214642	[572]	[58]	-7	hSpCas9	negative selection	492460
119997247	119997270	1	+	26472758	Raji	viability	GGAGAACTGGTTGGCCACAGTGG	NOTCH2	ENSG00000134250	-0.18539821385424649	[97]	[19]	-1	hSpCas9	negative selection	492470
119925702	119925725	1	+	26472758	K562	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-6.998755255806504	[302]	[1]	-9	hSpCas9	negative selection	683567
119925776	119925799	1	-	26472758	K562	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-1.0280760074164133	[458]	[189]	-5	hSpCas9	negative selection	683568
119925567	119925590	1	+	26472758	K562	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	-0.07587828164198718	[1104]	[884]	0	hSpCas9	negative selection	683569
119920279	119920302	1	+	26472758	K562	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-2.3057783548940325	[327]	[55]	-8	hSpCas9	negative selection	683570
119969569	119969592	1	+	26472758	K562	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	-0.55721430282732	[691]	[396]	-4	hSpCas9	negative selection	683571
119940693	119940716	1	+	26472758	K562	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	0.3603847457147718	[226]	[245]	3	hSpCas9	negative selection	683572
119937846	119937869	1	+	26472758	K562	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	-1.6255207317691802	[423]	[115]	-7	hSpCas9	negative selection	683573
119937369	119937392	1	+	26472758	K562	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	-0.39929061544512606	[613]	[392]	-3	hSpCas9	negative selection	683574
119929152	119929175	1	-	26472758	K562	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	-0.4595964446984726	[100]	[61]	-3	hSpCas9	negative selection	683575
119926554	119926577	1	-	26472758	K562	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	0.7631909486931366	[445]	[638]	6	hSpCas9	negative selection	683576
120005514	120005537	1	-	26472758	K562	viability	AAGAACCGCTGCCAGAATGGTGG	NOTCH2	ENSG00000134250	-2.644877807927333	[977]	[131]	-8	hSpCas9	negative selection	683578
119997247	119997270	1	+	26472758	K562	viability	GGAGAACTGGTTGGCCACAGTGG	NOTCH2	ENSG00000134250	-1.7111871529751	[127]	[32]	-7	hSpCas9	negative selection	683588
119965476	119965499	1	-	26627737	DLD1	viability	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.6878126215629965	[444]	[212,149,294]	6	hSpCas9	negative selection	765405
119966367	119966390	1	+	26627737	DLD1	viability	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-0.6414587729011898	[273]	[33,95,38]	-6	hSpCas9	negative selection	765406
119967513	119967536	1	+	26627737	DLD1	viability	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	0.10082919578293698	[420]	[104,195,126]	1	hSpCas9	negative selection	765407
119968114	119968137	1	+	26627737	DLD1	viability	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	-0.2433852688929946	[267]	[59,24,117]	-3	hSpCas9	negative selection	765408
119969569	119969592	1	+	26627737	DLD1	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.04126758509138081	[430]	[60,210,145]	0	hSpCas9	negative selection	765409
119987019	119987042	1	-	26627737	DLD1	viability	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	-0.20742082938414108	[836]	[178,316,192]	-2	hSpCas9	negative selection	765411
119965476	119965499	1	-	26627737	GBM cells	viability after 5 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.6023269093408652	[260]	[195,228]	8	hSpCas9	negative selection	847720
119966367	119966390	1	+	26627737	GBM cells	viability after 5 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-0.32715420459416067	[130]	[81,29]	-5	hSpCas9	negative selection	847721
119967513	119967536	1	+	26627737	GBM cells	viability after 5 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	0.35060984474337753	[203]	[129,148]	5	hSpCas9	negative selection	847722
119968114	119968137	1	+	26627737	GBM cells	viability after 5 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	1.3888798616710951	[67]	[98,91]	9	hSpCas9	negative selection	847723
119969569	119969592	1	+	26627737	GBM cells	viability after 5 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.5474415043843079	[184]	[144,144]	7	hSpCas9	negative selection	847724
119987019	119987042	1	-	26627737	GBM cells	viability after 5 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	0.6218042838401688	[411]	[358,320]	8	hSpCas9	negative selection	847726
119965476	119965499	1	-	26627737	GBM cells	viability after 13 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.7274150373188493	[260]	[266,207]	8	hSpCas9	negative selection	930035
119966367	119966390	1	+	26627737	GBM cells	viability after 13 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-0.05716455081352312	[130]	[80,57]	0	hSpCas9	negative selection	930036
119967513	119967536	1	+	26627737	GBM cells	viability after 13 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	0.9196738262717166	[203]	[215,203]	9	hSpCas9	negative selection	930037
119968114	119968137	1	+	26627737	GBM cells	viability after 13 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	1.0279779899594055	[67]	[61,85]	9	hSpCas9	negative selection	930038
119969569	119969592	1	+	26627737	GBM cells	viability after 13 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.22280803004245	[184]	[120,113]	3	hSpCas9	negative selection	930039
119987019	119987042	1	-	26627737	GBM cells	viability after 13 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	0.9489176787399439	[411]	[532,348]	9	hSpCas9	negative selection	930041
119965476	119965499	1	-	26627737	GBM cells	viability after 21 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.39475733767799515	[260]	[199,173]	4	hSpCas9	negative selection	1012350
119966367	119966390	1	+	26627737	GBM cells	viability after 21 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	0.0730619148702909	[130]	[77,71]	0	hSpCas9	negative selection	1012351
119967513	119967536	1	+	26627737	GBM cells	viability after 21 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	1.3882696985146925	[203]	[310,270]	9	hSpCas9	negative selection	1012352
119968114	119968137	1	+	26627737	GBM cells	viability after 21 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	1.7163950697336388	[67]	[111,129]	9	hSpCas9	negative selection	1012353
119969569	119969592	1	+	26627737	GBM cells	viability after 21 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.9437984283931246	[184]	[208,178]	8	hSpCas9	negative selection	1012354
119987019	119987042	1	-	26627737	GBM cells	viability after 21 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	1.1570142159341326	[411]	[495,501]	9	hSpCas9	negative selection	1012356
119965476	119965499	1	-	26627737	RPE1	viability after 9 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.04047249981022741	[901]	[251,339]	0	hSpCas9	negative selection	1094665
119966367	119966390	1	+	26627737	RPE1	viability after 9 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-0.10515233086528308	[271]	[100,50]	0	hSpCas9	negative selection	1094666
119967513	119967536	1	+	26627737	RPE1	viability after 9 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	1.4400002700225973	[478]	[343,487]	7	hSpCas9	negative selection	1094667
119968114	119968137	1	+	26627737	RPE1	viability after 9 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.3682307606222781	[381]	[149,159]	2	hSpCas9	negative selection	1094668
119969569	119969592	1	+	26627737	RPE1	viability after 9 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	9.214386834032673	[0]	[109,283]	9	hSpCas9	negative selection	1094669
119987019	119987042	1	-	26627737	RPE1	viability after 9 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	0.35878235374614276	[1442]	[453,740]	2	hSpCas9	negative selection	1094671
119965476	119965499	1	-	26627737	RPE1	viability after 12 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	-0.006273520838461333	[901]	[165,320]	0	hSpCas9	negative selection	1176980
119966367	119966390	1	+	26627737	RPE1	viability after 12 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-0.7843872308340396	[271]	[39,44]	-5	hSpCas9	negative selection	1176981
119967513	119967536	1	+	26627737	RPE1	viability after 12 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	1.3250653470711895	[478]	[370,270]	7	hSpCas9	negative selection	1176982
119968114	119968137	1	+	26627737	RPE1	viability after 12 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.4900381206861424	[381]	[131,156]	3	hSpCas9	negative selection	1176983
119969569	119969592	1	+	26627737	RPE1	viability after 12 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	9.199109291942332	[0]	[154,160]	9	hSpCas9	negative selection	1176984
119987019	119987042	1	-	26627737	RPE1	viability after 12 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	0.174818947300851	[1442]	[424,450]	1	hSpCas9	negative selection	1176986
119965476	119965499	1	-	26627737	RPE1	viability after 15 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	-0.18703492779577618	[901]	[272,176]	-1	hSpCas9	negative selection	1259295
119966367	119966390	1	+	26627737	RPE1	viability after 15 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-3.587540065373623	[271]	[11,0]	-9	hSpCas9	negative selection	1259296
119967513	119967536	1	+	26627737	RPE1	viability after 15 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	1.2887220634844425	[478]	[356,305]	7	hSpCas9	negative selection	1259297
119968114	119968137	1	+	26627737	RPE1	viability after 15 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.5478322107413405	[381]	[243,74]	3	hSpCas9	negative selection	1259298
119969569	119969592	1	+	26627737	RPE1	viability after 15 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	8.088196256165965	[0]	[77,75]	9	hSpCas9	negative selection	1259299
119987019	119987042	1	-	26627737	RPE1	viability after 15 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	-0.08833122293127893	[1442]	[442,326]	0	hSpCas9	negative selection	1259301
119965476	119965499	1	-	26627737	RPE1	viability after 18 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	-0.09829908366967699	[901]	[194,261]	0	hSpCas9	negative selection	1341610
119966367	119966390	1	+	26627737	RPE1	viability after 18 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-1.4180518902998527	[271]	[11,43]	-7	hSpCas9	negative selection	1341611
119967513	119967536	1	+	26627737	RPE1	viability after 18 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	1.2172919853988264	[478]	[345,251]	7	hSpCas9	negative selection	1341612
119968114	119968137	1	+	26627737	RPE1	viability after 18 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	1.0718042409771076	[381]	[207,225]	6	hSpCas9	negative selection	1341613
119969569	119969592	1	+	26627737	RPE1	viability after 18 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	9.19777001019282	[0]	[215,96]	9	hSpCas9	negative selection	1341614
119987019	119987042	1	-	26627737	RPE1	viability after 18 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	0.20251858308704285	[1442]	[392,506]	1	hSpCas9	negative selection	1341616
119965476	119965499	1	-	26627737	HeLa	viability after 8 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.6247379926016077	[329]	[252,193,223]	5	hSpCas9	negative selection	1423925
119966367	119966390	1	+	26627737	HeLa	viability after 8 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	0.8828665560420966	[109]	[130,51,90]	7	hSpCas9	negative selection	1423926
119967513	119967536	1	+	26627737	HeLa	viability after 8 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	-0.5602670011458623	[274]	[107,39,99]	-5	hSpCas9	negative selection	1423927
119968114	119968137	1	+	26627737	HeLa	viability after 8 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	-0.3844249318892212	[121]	[35,14,67]	-4	hSpCas9	negative selection	1423928
119969569	119969592	1	+	26627737	HeLa	viability after 8 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.6967113535549575	[201]	[174,182,80]	6	hSpCas9	negative selection	1423929
119987019	119987042	1	-	26627737	HeLa	viability after 8 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	0.8390064002093087	[581]	[741,469,226]	7	hSpCas9	negative selection	1423931
119965476	119965499	1	-	26627737	HeLa	viability after 12 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.6862298417362396	[329]	[220,137,307]	5	hSpCas9	negative selection	1506240
119966367	119966390	1	+	26627737	HeLa	viability after 12 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	0.27736634193910703	[109]	[22,48,92]	2	hSpCas9	negative selection	1506241
119967513	119967536	1	+	26627737	HeLa	viability after 12 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	0.2524340708271029	[274]	[100,164,135]	2	hSpCas9	negative selection	1506242
119968114	119968137	1	+	26627737	HeLa	viability after 12 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.25354564967565163	[121]	[41,76,58]	2	hSpCas9	negative selection	1506243
119969569	119969592	1	+	26627737	HeLa	viability after 12 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.6478671141405711	[201]	[68,211,100]	5	hSpCas9	negative selection	1506244
119987019	119987042	1	-	26627737	HeLa	viability after 12 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	0.14157933459659944	[581]	[194,273,323]	1	hSpCas9	negative selection	1506246
119965476	119965499	1	-	26627737	HeLa	viability after 15 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.3259913351062681	[329]	[206,149,145]	2	hSpCas9	negative selection	1588555
119966367	119966390	1	+	26627737	HeLa	viability after 15 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	0.9415855754346034	[109]	[149,83,17]	7	hSpCas9	negative selection	1588556
119967513	119967536	1	+	26627737	HeLa	viability after 15 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	0.059554112058071595	[274]	[111,73,167]	0	hSpCas9	negative selection	1588557
119968114	119968137	1	+	26627737	HeLa	viability after 15 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.6612292144474208	[121]	[65,124,41]	5	hSpCas9	negative selection	1588558
119969569	119969592	1	+	26627737	HeLa	viability after 15 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	1.3534871420977614	[201]	[167,70,406]	8	hSpCas9	negative selection	1588559
119987019	119987042	1	-	26627737	HeLa	viability after 15 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	0.35765964845773546	[581]	[275,453,170]	3	hSpCas9	negative selection	1588561
119965476	119965499	1	-	26627737	HeLa	viability after 18 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.33015444633711527	[329]	[135,128,145]	2	hSpCas9	negative selection	1670870
119966367	119966390	1	+	26627737	HeLa	viability after 18 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	0.9252079248916643	[109]	[95,72,17]	7	hSpCas9	negative selection	1670871
119967513	119967536	1	+	26627737	HeLa	viability after 18 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	0.11341343173273594	[274]	[83,60,167]	1	hSpCas9	negative selection	1670872
119968114	119968137	1	+	26627737	HeLa	viability after 18 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.6259917915217104	[121]	[40,102,41]	5	hSpCas9	negative selection	1670873
119969569	119969592	1	+	26627737	HeLa	viability after 18 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	1.3739734855124075	[201]	[115,61,406]	8	hSpCas9	negative selection	1670874
119987019	119987042	1	-	26627737	HeLa	viability after 18 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	0.3257305745713561	[581]	[176,369,170]	2	hSpCas9	negative selection	1670876
119965476	119965499	1	-	26627737	HCT116	viability after 6 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	-0.08020356277473316	[625]	[85,96]	0	hSpCas9	negative selection	1753185
119966367	119966390	1	+	26627737	HCT116	viability after 6 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	0.17284732571530914	[302]	[5,79]	1	hSpCas9	negative selection	1753186
119967513	119967536	1	+	26627737	HCT116	viability after 6 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	-1.0250279855136315	[812]	[163,6]	-5	hSpCas9	negative selection	1753187
119968114	119968137	1	+	26627737	HCT116	viability after 6 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	-0.8819139300773056	[255]	[55,2]	-5	hSpCas9	negative selection	1753188
119969569	119969592	1	+	26627737	HCT116	viability after 6 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.08636512666450313	[736]	[64,154]	0	hSpCas9	negative selection	1753189
119987019	119987042	1	-	26627737	HCT116	viability after 6 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	0.8426007108979554	[480]	[259,66]	4	hSpCas9	negative selection	1753191
119965476	119965499	1	-	26627737	HCT116	viability after 8 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	-0.05432820028247126	[349]	[174,195,185]	0	hSpCas9	negative selection	1835500
119966367	119966390	1	+	26627737	HCT116	viability after 8 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-0.1196701949538187	[173]	[79,129,54]	-1	hSpCas9	negative selection	1835501
119967513	119967536	1	+	26627737	HCT116	viability after 8 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	0.6720782938729403	[214]	[248,180,137]	6	hSpCas9	negative selection	1835502
119968114	119968137	1	+	26627737	HCT116	viability after 8 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.6502236948573521	[76]	[113,51,34]	6	hSpCas9	negative selection	1835503
119969569	119969592	1	+	26627737	HCT116	viability after 8 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.3922832058206517	[218]	[150,81,240]	4	hSpCas9	negative selection	1835504
119987019	119987042	1	-	26627737	HCT116	viability after 8 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	-0.2505968583073168	[512]	[174,241,293]	-3	hSpCas9	negative selection	1835506
119965476	119965499	1	-	26627737	HCT116	viability after 9 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	-1.323213924587263	[625]	[144,4]	-7	hSpCas9	negative selection	1917815
119966367	119966390	1	+	26627737	HCT116	viability after 9 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-0.8725626173629875	[302]	[8,71]	-6	hSpCas9	negative selection	1917816
119967513	119967536	1	+	26627737	HCT116	viability after 9 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	-0.6820364594682216	[812]	[36,212]	-5	hSpCas9	negative selection	1917817
119968114	119968137	1	+	26627737	HCT116	viability after 9 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	1.9713214674915296	[255]	[486,94]	9	hSpCas9	negative selection	1917818
119969569	119969592	1	+	26627737	HCT116	viability after 9 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	-0.29633017474019907	[736]	[71,229]	-2	hSpCas9	negative selection	1917819
119987019	119987042	1	-	26627737	HCT116	viability after 9 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	1.4991730795360128	[480]	[619,159]	8	hSpCas9	negative selection	1917821
119965476	119965499	1	-	26627737	HCT116	viability after 12 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.09627918962955204	[349]	[200,175,211]	1	hSpCas9	negative selection	2000130
119966367	119966390	1	+	26627737	HCT116	viability after 12 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-0.12217679597508624	[173]	[29,174,53]	-1	hSpCas9	negative selection	2000131
119967513	119967536	1	+	26627737	HCT116	viability after 12 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	0.5699906294205533	[214]	[126,176,202]	5	hSpCas9	negative selection	2000132
119968114	119968137	1	+	26627737	HCT116	viability after 12 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.9618692162595688	[76]	[147,62,18]	7	hSpCas9	negative selection	2000133
119969569	119969592	1	+	26627737	HCT116	viability after 12 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.07624837198581069	[218]	[102,136,125]	0	hSpCas9	negative selection	2000134
119987019	119987042	1	-	26627737	HCT116	viability after 12 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	-0.5616813010317359	[512]	[176,204,166]	-6	hSpCas9	negative selection	2000136
119965476	119965499	1	-	26627737	HCT116	viability after 15 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	-0.10963555498297958	[349]	[172,175,207]	-1	hSpCas9	negative selection	2082445
119966367	119966390	1	+	26627737	HCT116	viability after 15 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	0.22532646382194055	[173]	[217,46,97]	2	hSpCas9	negative selection	2082446
119967513	119967536	1	+	26627737	HCT116	viability after 15 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	0.613255391035473	[214]	[240,144,186]	5	hSpCas9	negative selection	2082447
119968114	119968137	1	+	26627737	HCT116	viability after 15 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	1.1146801057013718	[76]	[179,60,56]	8	hSpCas9	negative selection	2082448
119969569	119969592	1	+	26627737	HCT116	viability after 15 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.0235524573729331	[218]	[185,109,94]	0	hSpCas9	negative selection	2082449
119987019	119987042	1	-	26627737	HCT116	viability after 15 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	-0.17961911882004333	[512]	[237,222,315]	-2	hSpCas9	negative selection	2082451
119965476	119965499	1	-	26627737	HCT116	viability after 18 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.28992686833304426	[349]	[176,172,275]	2	hSpCas9	negative selection	2164760
119966367	119966390	1	+	26627737	HCT116	viability after 18 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	0.9478651271647154	[173]	[223,160,98]	7	hSpCas9	negative selection	2164761
119967513	119967536	1	+	26627737	HCT116	viability after 18 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	0.231481644471351	[214]	[181,63,123]	2	hSpCas9	negative selection	2164762
119968114	119968137	1	+	26627737	HCT116	viability after 18 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	1.0235726868599004	[76]	[148,62,12]	7	hSpCas9	negative selection	2164763
119969569	119969592	1	+	26627737	HCT116	viability after 18 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.2557118350453761	[218]	[176,98,103]	2	hSpCas9	negative selection	2164764
119987019	119987042	1	-	26627737	HCT116	viability after 18 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	-0.5952262300720945	[512]	[144,124,227]	-5	hSpCas9	negative selection	2164766
119944383	119944406	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAATCAGCCGGGCGTGGTGGCGG	NOTCH2	ENSG00000134250	2.666493729320144	[0,0]	[2,0]	8	dCas9-VP64	positive selection	2406275
119991781	119991804	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCGCCATTGCACTCCAGCCTGG	NOTCH2	ENSG00000134250	3.6537831084481405	[32,65]	[34,252]	9	dCas9-VP64	positive selection	2411017
119938834	119938857	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TACAAAAAATTAGCCGGGTGTGG	NOTCH2	ENSG00000134250	0.005790697324581817	[8,20]	[2,2]	0	dCas9-VP64	positive selection	2434942
120001002	120001025	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTATCATGAGAATAGCACAG	NOTCH2	ENSG00000134250	-1.1176480742477737	[118,81]	[12,5]	-6	dCas9-VP64	positive selection	2441720
119944383	119944406	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAATCAGCCGGGCGTGGTGGCGG	NOTCH2	ENSG00000134250	4.409340511338286	[107,137]	[18,1641]	9	dCas9-VP64	positive selection	2501530
119991781	119991804	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCGCCATTGCACTCCAGCCTGG	NOTCH2	ENSG00000134250	1.263366329430324	[331,132]	[69,289]	7	dCas9-VP64	positive selection	2506272
119938834	119938857	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TACAAAAAATTAGCCGGGTGTGG	NOTCH2	ENSG00000134250	1.0784968234287284	[5,24]	[2,16]	7	dCas9-VP64	positive selection	2530197
120001002	120001025	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTATCATGAGAATAGCACAG	NOTCH2	ENSG00000134250	-0.17970757068905518	[61,56]	[17,15]	-2	dCas9-VP64	positive selection	2536975
119967545	119967568	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AACCCTTCAGACACTCACAGTGG	NOTCH2	ENSG00000134250	0.4232148561729133	[2,3]	[2,4]	8	hSpCas9	positive selection	3006096
119937988	119938011	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCGACTGCAGAGATTCACCAGGG	NOTCH2	ENSG00000134250	0.27580235619598786	[3,3]	[3,3]	6	hSpCas9	positive selection	3006097
120069371	120069394	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCGCCCACAGCAGAGCGGGG	NOTCH2	ENSG00000134250	0.20589721766894684	[2,2]	[3,1]	4	hSpCas9	positive selection	3006098
119955128	119955151	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTCCGCTGTATATGCCCCGAGG	NOTCH2	ENSG00000134250	-0.23654656171820534	[3,3]	[3,1]	-3	hSpCas9	positive selection	3006099
119967545	119967568	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AACCCTTCAGACACTCACAGTGG	NOTCH2	ENSG00000134250	-0.24865968695553262	[2,2]	[1,0]	-4	hSpCas9	positive selection	3073954
119937988	119938011	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCGACTGCAGAGATTCACCAGGG	NOTCH2	ENSG00000134250	-0.05033742812721014	[3,3]	[3,1]	0	hSpCas9	positive selection	3073955
120069371	120069394	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCGCCCACAGCAGAGCGGGG	NOTCH2	ENSG00000134250	-0.14980466569696088	[2,2]	[1,0]	-2	hSpCas9	positive selection	3073956
119955128	119955151	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTCCGCTGTATATGCCCCGAGG	NOTCH2	ENSG00000134250	-0.24794170877533783	[3,3]	[2,1]	-4	hSpCas9	positive selection	3073957
119997300	119997323		+	24336571	A375	resistance to PLX after 7 days	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	-0.597724639408451	[4,5]	[2,2]	-9	hSpCas9	positive selection	3131199
120005419	120005442		+	24336571	A375	resistance to PLX after 7 days	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.06390649421760841	[1,1]	[1,1]	-2	hSpCas9	positive selection	3131200
119997050	119997073		-	24336571	A375	resistance to PLX after 7 days	GCACCCTCACCTTGTGTCAATGG	NOTCH2	ENSG00000134250	-0.011126557477943777	[1,2]	[2,1]	0	hSpCas9	positive selection	3131201
119997046	119997069		+	24336571	A375	resistance to PLX after 7 days	GCCTCCATTGACACAAGGTGAGG	NOTCH2	ENSG00000134250	-0.4711017561808366	[1,2]	[1,1]	-9	hSpCas9	positive selection	3131202
120005391	120005414		-	24336571	A375	resistance to PLX after 7 days	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.08230365212828739	[1,1]	[1,1]	-2	hSpCas9	positive selection	3131203
119997300	119997323		+	24336571	A375	resistance to PLX after 14 days	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.16682106207605774	[3,3]	[1,1]	1	hSpCas9	positive selection	3188992
120005419	120005442		+	24336571	A375	resistance to PLX after 14 days	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	1.4255238677792554	[1,1]	[2,1]	8	hSpCas9	positive selection	3188993
119997050	119997073		-	24336571	A375	resistance to PLX after 14 days	GCACCCTCACCTTGTGTCAATGG	NOTCH2	ENSG00000134250	1.0680254535626186	[1,1]	[1,1]	8	hSpCas9	positive selection	3188994
119997046	119997069		+	24336571	A375	resistance to PLX after 14 days	GCCTCCATTGACACAAGGTGAGG	NOTCH2	ENSG00000134250	0.8369077699090779	[1,1]	[1,1]	7	hSpCas9	positive selection	3188995
120005391	120005414		-	24336571	A375	resistance to PLX after 14 days	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.9678356523917839	[1,1]	[1,1]	7	hSpCas9	positive selection	3188996
119997300	119997323		+	24336571	A375	viability after 7 days	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	1.141491855727739	[1]	[4,5]	9	hSpCas9	negative selection	3246785
120005419	120005442		+	24336571	A375	viability after 7 days	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	0.2918439573646796	[1]	[1,1]	4	hSpCas9	negative selection	3246786
119997050	119997073		-	24336571	A375	viability after 7 days	GCACCCTCACCTTGTGTCAATGG	NOTCH2	ENSG00000134250	0.39857279808237456	[1]	[1,2]	6	hSpCas9	negative selection	3246787
119997046	119997069		+	24336571	A375	viability after 7 days	GCCTCCATTGACACAAGGTGAGG	NOTCH2	ENSG00000134250	0.3085723205330022	[1]	[1,2]	5	hSpCas9	negative selection	3246788
120005391	120005414		-	24336571	A375	viability after 7 days	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.2754653217991154	[1]	[1,1]	4	hSpCas9	negative selection	3246789
119997300	119997323		+	24336571	A375	viability after 14 days	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.8237510492182296	[1]	[3,3]	9	hSpCas9	negative selection	3304578
120005419	120005442		+	24336571	A375	viability after 14 days	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	0.23381047948205635	[1]	[1,1]	3	hSpCas9	negative selection	3304579
119997050	119997073		-	24336571	A375	viability after 14 days	GCACCCTCACCTTGTGTCAATGG	NOTCH2	ENSG00000134250	0.22765071989856578	[1]	[1,1]	3	hSpCas9	negative selection	3304580
119997046	119997069		+	24336571	A375	viability after 14 days	GCCTCCATTGACACAAGGTGAGG	NOTCH2	ENSG00000134250	0.05085227733760567	[1]	[1,1]	0	hSpCas9	negative selection	3304581
120005391	120005414		-	24336571	A375	viability after 14 days	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.2193104544819171	[1]	[1,1]	3	hSpCas9	negative selection	3304582
120005419	120005442	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	3.087401210003523	[17,17]	[0,0]	8	hSpCas9	positive selection	3382082
119997114	119997137	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	-0.09140194278524238	[325,325]	[1,1]	0	hSpCas9	positive selection	3382083
120005391	120005414	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.8650087886670746	[83,83]	[0,0]	4	hSpCas9	positive selection	3382084
119967544	119967567	1	+	26780180	HT29	viability (Avana library 4 designs)	AACCCTTCAGACACTCACAGTGG	NOTCH2	ENSG00000134250	0.848382320954662	[]	[]	3	hSpCas9	negative selection	3443954
119937987	119938010	1	+	26780180	HT29	viability (Avana library 4 designs)	CCGACTGCAGAGATTCACCAGGG	NOTCH2	ENSG00000134250	0.893169278458567	[]	[]	3	hSpCas9	negative selection	3443955
120069370	120069393	1	+	26780180	HT29	viability (Avana library 4 designs)	GCAGCGCCCACAGCAGAGCGGGG	NOTCH2	ENSG00000134250	2.10953118479622	[]	[]	7	hSpCas9	negative selection	3443956
119955128	119955151	1	-	26780180	HT29	viability (Avana library 4 designs)	TTTCCGCTGTATATGCCCCGAGG	NOTCH2	ENSG00000134250	1.86134639118443	[]	[]	7	hSpCas9	negative selection	3443957
119937987	119938010	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCGACTGCAGAGATTCACCAGGG	NOTCH2	ENSG00000134250	-7.34011303420817	[]	[]	-6	hSpCas9	negative selection	3535901
119955128	119955151	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCCGCTGTATATGCCCCGAGG	NOTCH2	ENSG00000134250	3.37890785279356	[]	[]	5	hSpCas9	negative selection	3535902
120069370	120069393	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCGCCCACAGCAGAGCGGGG	NOTCH2	ENSG00000134250	4.11793030285082	[]	[]	6	hSpCas9	negative selection	3535903
119967544	119967567	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	AACCCTTCAGACACTCACAGTGG	NOTCH2	ENSG00000134250	-8.26883510881262	[]	[]	-7	hSpCas9	negative selection	3535904
119965476	119965499	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	2.59492836731035	[]	[]	4	hSpCas9	negative selection	3535905
119966418	119966441	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGCCCATTGTTCACACAAGGG	NOTCH2	ENSG00000134250	-0.718848497891125	[]	[]	-1	hSpCas9	negative selection	3535906
119937987	119938010	1	+	26780180	A375	viability (Avana lentiGuide)	CCGACTGCAGAGATTCACCAGGG	NOTCH2	ENSG00000134250	0.651890382197006	[]	[]	0	hSpCas9	negative selection	3644560
119955128	119955151	1	-	26780180	A375	viability (Avana lentiGuide)	TTTCCGCTGTATATGCCCCGAGG	NOTCH2	ENSG00000134250	1.13390940784902	[]	[]	1	hSpCas9	negative selection	3644561
120069370	120069393	1	+	26780180	A375	viability (Avana lentiGuide)	GCAGCGCCCACAGCAGAGCGGGG	NOTCH2	ENSG00000134250	-5.84312435791296	[]	[]	-8	hSpCas9	negative selection	3644562
119967544	119967567	1	+	26780180	A375	viability (Avana lentiGuide)	AACCCTTCAGACACTCACAGTGG	NOTCH2	ENSG00000134250	-4.24463645060287	[]	[]	-7	hSpCas9	negative selection	3644563
119965476	119965499	1	-	26780180	A375	viability (Avana lentiGuide)	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	3.17555728079546	[]	[]	3	hSpCas9	negative selection	3644564
119966418	119966441	1	+	26780180	A375	viability (Avana lentiGuide)	ACTGCCCATTGTTCACACAAGGG	NOTCH2	ENSG00000134250	-2.43396672411644	[]	[]	-4	hSpCas9	negative selection	3644565
119937987	119938010	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCGACTGCAGAGATTCACCAGGG	NOTCH2	ENSG00000134250	-0.2464569475750174	[4]	[3,3]	-4	hSpCas9	positive selection	3753219
119955128	119955151	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCCGCTGTATATGCCCCGAGG	NOTCH2	ENSG00000134250	0.2878635038937007	[5]	[6,5]	8	hSpCas9	positive selection	3753220
120069370	120069393	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCGCCCACAGCAGAGCGGGG	NOTCH2	ENSG00000134250	0.14298831069119294	[3]	[3,3]	4	hSpCas9	positive selection	3753221
119967544	119967567	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AACCCTTCAGACACTCACAGTGG	NOTCH2	ENSG00000134250	-0.0009929673565262954	[4]	[4,4]	0	hSpCas9	positive selection	3753222
119965476	119965499	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.10360232009632511	[5]	[6,5]	2	hSpCas9	positive selection	3753223
119966418	119966441	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGCCCATTGTTCACACAAGGG	NOTCH2	ENSG00000134250	-0.12439012778938476	[6]	[5,5]	-2	hSpCas9	positive selection	3753224
119937987	119938010	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCGACTGCAGAGATTCACCAGGG	NOTCH2	ENSG00000134250	-0.17160755366515748	[5]	[2,4]	-2	hSpCas9	positive selection	3861826
119955128	119955151	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCCGCTGTATATGCCCCGAGG	NOTCH2	ENSG00000134250	-0.2806814443781602	[6]	[2,4]	-4	hSpCas9	positive selection	3861827
120069370	120069393	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCGCCCACAGCAGAGCGGGG	NOTCH2	ENSG00000134250	-0.8783792666635821	[3]	[1,0]	-8	hSpCas9	positive selection	3861828
119967544	119967567	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AACCCTTCAGACACTCACAGTGG	NOTCH2	ENSG00000134250	0.4472287510868801	[4]	[5,4]	9	hSpCas9	positive selection	3861829
119965476	119965499	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.0809116399120472	[5]	[4,4]	1	hSpCas9	positive selection	3861830
119966418	119966441	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGCCCATTGTTCACACAAGGG	NOTCH2	ENSG00000134250	0.3015262813541718	[5]	[6,6]	8	hSpCas9	positive selection	3861831
119997300	119997323	1	+	26780180	A375	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.217838548298961	[]	[]	0	hSpCas9	negative selection	3973148
120005419	120005442	1	+	26780180	A375	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	1.08523040289157	[]	[]	5	hSpCas9	negative selection	3973149
119997114	119997137	1	-	26780180	A375	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.631597364065936	[]	[]	2	hSpCas9	negative selection	3973150
119986950	119986973	1	+	26780180	A375	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	1.4230086945703	[]	[]	7	hSpCas9	negative selection	3973151
120005391	120005414	1	-	26780180	A375	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.837268978700019	[]	[]	3	hSpCas9	negative selection	3973152
119987030	119987053	1	-	26780180	A375	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	1.28385508225377	[]	[]	7	hSpCas9	negative selection	3973153
119997300	119997323	1	+	26780180	HT29	viability (GeCKOv2 library)	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.123541702662196	[]	[]	0	hSpCas9	negative selection	4081114
120005419	120005442	1	+	26780180	HT29	viability (GeCKOv2 library)	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	1.03428116057738	[]	[]	5	hSpCas9	negative selection	4081115
119997114	119997137	1	-	26780180	HT29	viability (GeCKOv2 library)	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	1.07965971408982	[]	[]	5	hSpCas9	negative selection	4081116
119986950	119986973	1	+	26780180	HT29	viability (GeCKOv2 library)	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.349282278754708	[]	[]	1	hSpCas9	negative selection	4081117
120005391	120005414	1	-	26780180	HT29	viability (GeCKOv2 library)	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.91396872105018	[]	[]	4	hSpCas9	negative selection	4081118
119987030	119987053	1	-	26780180	HT29	viability (GeCKOv2 library)	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	1.20075010557307	[]	[]	6	hSpCas9	negative selection	4081119
119997300	119997323	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	-0.486997560677508	[4]	[3,0]	-8	hSpCas9	positive selection	4155889
120005419	120005442	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.06532750391992798	[2]	[2,0]	-1	hSpCas9	positive selection	4155890
119997050	119997073	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCACCCTCACCTTGTGTCAATGG	NOTCH2	ENSG00000134250	-0.3934790799757603	[3]	[2,0]	-7	hSpCas9	positive selection	4155891
119997046	119997069	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCTCCATTGACACAAGGTGAGG	NOTCH2	ENSG00000134250	-0.49285210613841823	[3]	[2,0]	-8	hSpCas9	positive selection	4155892
120005391	120005414	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.9964186931868355	[3]	[1,0]	-9	hSpCas9	positive selection	4155893
119997300	119997323	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.008740044876581421	[4]	[3,3,1,0]	0	hSpCas9	positive selection	4219911
120005419	120005442	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.3652803680179351	[3]	[0,3,0,0]	-5	hSpCas9	positive selection	4219912
119997050	119997073	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCACCCTCACCTTGTGTCAATGG	NOTCH2	ENSG00000134250	0.5365928594488886	[2]	[2,1,3,0]	3	hSpCas9	positive selection	4219913
119997046	119997069	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCTCCATTGACACAAGGTGAGG	NOTCH2	ENSG00000134250	-0.47743248925674925	[4]	[4,0,0,0]	-6	hSpCas9	positive selection	4219914
120005391	120005414	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.4773772324474931	[3]	[1,0,0,0]	-6	hSpCas9	positive selection	4219915
119997300	119997323	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.27172830193631103	[4]	[4,4]	5	hSpCas9	positive selection	4285998
119986950	119986973	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.22980924144215548	[4]	[4,3]	4	hSpCas9	positive selection	4285999
119987030	119987053	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.16376047194799032	[4]	[3,3]	3	hSpCas9	positive selection	4286000
120005419	120005442	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.15364787374327826	[1]	[1,0]	-3	hSpCas9	positive selection	4350255
119997114	119997137	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.01091522540367007	[3]	[3,2]	0	hSpCas9	positive selection	4350256
120005391	120005414	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.002977796655021847	[1]	[1,1]	0	hSpCas9	positive selection	4350257
119937886	119937908	1	+	27760321	OCIAML3	viability	ACATTGGGCACGTCACAATAGG	NOTCH2	ENSG00000134250	0.7318947338704067	[237,195]	[214,365]	8	hSpCas9	negative selection	4422998
119955127	119955149	1	-	27760321	OCIAML3	viability	TCCGCTGTATATGCCCCGAGGG	NOTCH2	ENSG00000134250	-0.15291798205695462	[947,699]	[533,626]	-2	hSpCas9	negative selection	4422999
119955169	119955191	1	+	27760321	OCIAML3	viability	CATGTTGCACCCTTGCGACAGG	NOTCH2	ENSG00000134250	0.17468768682355426	[464,419]	[424,344]	2	hSpCas9	negative selection	4423000
119963626	119963648	1	+	27760321	OCIAML3	viability	GCGACCATCGTTCAGGCAAGGG	NOTCH2	ENSG00000134250	1.0987880981647713	[700,570]	[956,1193]	9	hSpCas9	negative selection	4423001
119965501	119965523	1	-	27760321	OCIAML3	viability	AGTACTCCGTGTCTGAATGGGG	NOTCH2	ENSG00000134250	0.22491430580744787	[372,385]	[252,472]	2	hSpCas9	negative selection	4423002
119937886	119937908	1	+	27760321	OCIAML2	viability	ACATTGGGCACGTCACAATAGG	NOTCH2	ENSG00000134250	0.8500598616442953	[237,195]	[320,306]	9	hSpCas9	negative selection	4506461
119955127	119955149	1	-	27760321	OCIAML2	viability	TCCGCTGTATATGCCCCGAGGG	NOTCH2	ENSG00000134250	-0.1920073981311219	[947,699]	[544,621]	-2	hSpCas9	negative selection	4506462
119955169	119955191	1	+	27760321	OCIAML2	viability	CATGTTGCACCCTTGCGACAGG	NOTCH2	ENSG00000134250	0.15933489992685043	[464,419]	[401,395]	2	hSpCas9	negative selection	4506463
119963626	119963648	1	+	27760321	OCIAML2	viability	GCGACCATCGTTCAGGCAAGGG	NOTCH2	ENSG00000134250	0.21553152463746983	[700,570]	[542,661]	3	hSpCas9	negative selection	4506464
119965501	119965523	1	-	27760321	OCIAML2	viability	AGTACTCCGTGTCTGAATGGGG	NOTCH2	ENSG00000134250	-0.13973986610638187	[372,385]	[263,300]	-2	hSpCas9	negative selection	4506465
119937886	119937908	1	+	27760321	MV411	viability	ACATTGGGCACGTCACAATAGG	NOTCH2	ENSG00000134250	1.2746039142828378	[237,195]	[379,291]	8	hSpCas9	negative selection	4589924
119955127	119955149	1	-	27760321	MV411	viability	TCCGCTGTATATGCCCCGAGGG	NOTCH2	ENSG00000134250	-0.4163024386936354	[947,699]	[121,826]	-3	hSpCas9	negative selection	4589925
119955169	119955191	1	+	27760321	MV411	viability	CATGTTGCACCCTTGCGACAGG	NOTCH2	ENSG00000134250	0.23868137332722877	[464,419]	[386,279]	1	hSpCas9	negative selection	4589926
119963626	119963648	1	+	27760321	MV411	viability	GCGACCATCGTTCAGGCAAGGG	NOTCH2	ENSG00000134250	0.470524741107055	[700,570]	[540,634]	3	hSpCas9	negative selection	4589927
119965501	119965523	1	-	27760321	MV411	viability	AGTACTCCGTGTCTGAATGGGG	NOTCH2	ENSG00000134250	-1.0399043984192804	[372,385]	[87,173]	-6	hSpCas9	negative selection	4589928
119937886	119937908	1	+	27760321	HL60	viability	ACATTGGGCACGTCACAATAGG	NOTCH2	ENSG00000134250	0.1980432542870426	[237,195]	[198,205]	2	hSpCas9	negative selection	4673387
119955127	119955149	1	-	27760321	HL60	viability	TCCGCTGTATATGCCCCGAGGG	NOTCH2	ENSG00000134250	-0.2563893697855457	[947,699]	[637,473]	-3	hSpCas9	negative selection	4673388
119955169	119955191	1	+	27760321	HL60	viability	CATGTTGCACCCTTGCGACAGG	NOTCH2	ENSG00000134250	-0.2593959054745995	[464,419]	[341,258]	-3	hSpCas9	negative selection	4673389
119963626	119963648	1	+	27760321	HL60	viability	GCGACCATCGTTCAGGCAAGGG	NOTCH2	ENSG00000134250	0.7765867242897804	[700,570]	[883,886]	8	hSpCas9	negative selection	4673390
119965501	119965523	1	-	27760321	HL60	viability	AGTACTCCGTGTCTGAATGGGG	NOTCH2	ENSG00000134250	-0.278330855798807	[372,385]	[233,280]	-3	hSpCas9	negative selection	4673391
119937886	119937908	1	+	27760321	HT1080	viability	ACATTGGGCACGTCACAATAGG	NOTCH2	ENSG00000134250	2.6365581655756287	[195,152]	[353,517]	9	hSpCas9	negative selection	4756850
119955127	119955149	1	-	27760321	HT1080	viability	TCCGCTGTATATGCCCCGAGGG	NOTCH2	ENSG00000134250	1.9097012357041996	[699,545]	[952,909]	8	hSpCas9	negative selection	4756851
119955169	119955191	1	+	27760321	HT1080	viability	CATGTTGCACCCTTGCGACAGG	NOTCH2	ENSG00000134250	3.304650591307761	[419,327]	[2024,866]	9	hSpCas9	negative selection	4756852
119963626	119963648	1	+	27760321	HT1080	viability	GCGACCATCGTTCAGGCAAGGG	NOTCH2	ENSG00000134250	1.7508422854375087	[570,445]	[666,697]	8	hSpCas9	negative selection	4756853
119965501	119965523	1	-	27760321	HT1080	viability	AGTACTCCGTGTCTGAATGGGG	NOTCH2	ENSG00000134250	2.3112395954504406	[385,300]	[670,687]	9	hSpCas9	negative selection	4756854
119937886	119937908	1	+	27760321	HT29	viability after 7 days	ACATTGGGCACGTCACAATAGG	NOTCH2	ENSG00000134250	0.21212757894582657	[195,152]	[281,193,304]	3	hSpCas9	negative selection	4840313
119955127	119955149	1	-	27760321	HT29	viability after 7 days	TCCGCTGTATATGCCCCGAGGG	NOTCH2	ENSG00000134250	-0.02304654469365508	[699,545]	[828,831,710]	0	hSpCas9	negative selection	4840314
119955169	119955191	1	+	27760321	HT29	viability after 7 days	CATGTTGCACCCTTGCGACAGG	NOTCH2	ENSG00000134250	-0.4744327168378075	[419,327]	[528,318,219]	-6	hSpCas9	negative selection	4840315
119963626	119963648	1	+	27760321	HT29	viability after 7 days	GCGACCATCGTTCAGGCAAGGG	NOTCH2	ENSG00000134250	0.7563461959117017	[570,445]	[1380,956,1015]	9	hSpCas9	negative selection	4840316
119965501	119965523	1	-	27760321	HT29	viability after 7 days	AGTACTCCGTGTCTGAATGGGG	NOTCH2	ENSG00000134250	-1.054398011971238	[385,300]	[303,240,108]	-8	hSpCas9	negative selection	4840317
119937886	119937908	1	+	27760321	HT29	viability after 25 days	ACATTGGGCACGTCACAATAGG	NOTCH2	ENSG00000134250	0.8769245979125829	[195,152]	[563,238,272]	8	hSpCas9	negative selection	4923776
119955127	119955149	1	-	27760321	HT29	viability after 25 days	TCCGCTGTATATGCCCCGAGGG	NOTCH2	ENSG00000134250	0.3065886425705455	[699,545]	[730,862,1075]	3	hSpCas9	negative selection	4923777
119955169	119955191	1	+	27760321	HT29	viability after 25 days	CATGTTGCACCCTTGCGACAGG	NOTCH2	ENSG00000134250	-0.40949813531991364	[419,327]	[219,354,404]	-4	hSpCas9	negative selection	4923778
119963626	119963648	1	+	27760321	HT29	viability after 25 days	GCGACCATCGTTCAGGCAAGGG	NOTCH2	ENSG00000134250	0.46609385432184136	[570,445]	[690,921,800]	5	hSpCas9	negative selection	4923779
119965501	119965523	1	-	27760321	HT29	viability after 25 days	AGTACTCCGTGTCTGAATGGGG	NOTCH2	ENSG00000134250	-0.7937712979505033	[385,300]	[143,357,176]	-6	hSpCas9	negative selection	4923780
119937886	119937908	1	+	27760321	HT29	viability after 22 days	ACATTGGGCACGTCACAATAGG	NOTCH2	ENSG00000134250	0.5921020558999228	[195,152]	[392,200,315]	6	hSpCas9	negative selection	5007239
119955127	119955149	1	-	27760321	HT29	viability after 22 days	TCCGCTGTATATGCCCCGAGGG	NOTCH2	ENSG00000134250	0.1710302331784206	[699,545]	[815,840,774]	1	hSpCas9	negative selection	5007240
119955169	119955191	1	+	27760321	HT29	viability after 22 days	CATGTTGCACCCTTGCGACAGG	NOTCH2	ENSG00000134250	0.10608656921004186	[419,327]	[421,537,436]	1	hSpCas9	negative selection	5007241
119963626	119963648	1	+	27760321	HT29	viability after 22 days	GCGACCATCGTTCAGGCAAGGG	NOTCH2	ENSG00000134250	0.3889549972449434	[570,445]	[793,922,589]	4	hSpCas9	negative selection	5007242
119965501	119965523	1	-	27760321	HT29	viability after 22 days	AGTACTCCGTGTCTGAATGGGG	NOTCH2	ENSG00000134250	-0.01571287986859214	[385,300]	[705,369,90]	0	hSpCas9	negative selection	5007243
119937886	119937908	1	+	27760321	HT29	viability after 19 days	ACATTGGGCACGTCACAATAGG	NOTCH2	ENSG00000134250	0.4825664148426003	[195,152]	[362,171,308]	5	hSpCas9	negative selection	5090702
119955127	119955149	1	-	27760321	HT29	viability after 19 days	TCCGCTGTATATGCCCCGAGGG	NOTCH2	ENSG00000134250	0.5191045775925476	[699,545]	[998,1331,739]	5	hSpCas9	negative selection	5090703
119955169	119955191	1	+	27760321	HT29	viability after 19 days	CATGTTGCACCCTTGCGACAGG	NOTCH2	ENSG00000134250	-0.27868866074499843	[419,327]	[379,502,183]	-3	hSpCas9	negative selection	5090704
119963626	119963648	1	+	27760321	HT29	viability after 19 days	GCGACCATCGTTCAGGCAAGGG	NOTCH2	ENSG00000134250	0.518698570566555	[570,445]	[894,949,666]	5	hSpCas9	negative selection	5090705
119965501	119965523	1	-	27760321	HT29	viability after 19 days	AGTACTCCGTGTCTGAATGGGG	NOTCH2	ENSG00000134250	-1.207788060092058	[385,300]	[216,234,66]	-7	hSpCas9	negative selection	5090706
119937886	119937908	1	+	27760321	HT29	viability after 16 days	ACATTGGGCACGTCACAATAGG	NOTCH2	ENSG00000134250	-0.10782814510989236	[195,152]	[213,88,245]	-1	hSpCas9	negative selection	5174165
119955127	119955149	1	-	27760321	HT29	viability after 16 days	TCCGCTGTATATGCCCCGAGGG	NOTCH2	ENSG00000134250	0.46453165708550914	[699,545]	[980,958,946]	5	hSpCas9	negative selection	5174166
119955169	119955191	1	+	27760321	HT29	viability after 16 days	CATGTTGCACCCTTGCGACAGG	NOTCH2	ENSG00000134250	-0.05964483649896901	[419,327]	[652,255,322]	0	hSpCas9	negative selection	5174167
119963626	119963648	1	+	27760321	HT29	viability after 16 days	GCGACCATCGTTCAGGCAAGGG	NOTCH2	ENSG00000134250	0.46715588595237734	[570,445]	[770,1011,568]	5	hSpCas9	negative selection	5174168
119965501	119965523	1	-	27760321	HT29	viability after 16 days	AGTACTCCGTGTCTGAATGGGG	NOTCH2	ENSG00000134250	-1.0846871276598427	[385,300]	[178,193,169]	-7	hSpCas9	negative selection	5174169
119937886	119937908	1	+	27760321	HT29	viability after 13 days	ACATTGGGCACGTCACAATAGG	NOTCH2	ENSG00000134250	0.5564281461594187	[195,152]	[170,366,351]	7	hSpCas9	negative selection	5257628
119955127	119955149	1	-	27760321	HT29	viability after 13 days	TCCGCTGTATATGCCCCGAGGG	NOTCH2	ENSG00000134250	-0.11265973225423553	[699,545]	[614,733,656]	-1	hSpCas9	negative selection	5257629
119955169	119955191	1	+	27760321	HT29	viability after 13 days	CATGTTGCACCCTTGCGACAGG	NOTCH2	ENSG00000134250	-0.10785960113930952	[419,327]	[349,506,353]	-1	hSpCas9	negative selection	5257630
119963626	119963648	1	+	27760321	HT29	viability after 13 days	GCGACCATCGTTCAGGCAAGGG	NOTCH2	ENSG00000134250	0.5405613314771938	[570,445]	[1004,918,661]	7	hSpCas9	negative selection	5257631
119965501	119965523	1	-	27760321	HT29	viability after 13 days	AGTACTCCGTGTCTGAATGGGG	NOTCH2	ENSG00000134250	-0.011936830164115439	[385,300]	[651,360,184]	0	hSpCas9	negative selection	5257632
119937886	119937908	1	+	27760321	HT29	viability after 10 days	ACATTGGGCACGTCACAATAGG	NOTCH2	ENSG00000134250	0.24102064099458076	[195,152]	[247,212,308]	3	hSpCas9	negative selection	5341091
119955127	119955149	1	-	27760321	HT29	viability after 10 days	TCCGCTGTATATGCCCCGAGGG	NOTCH2	ENSG00000134250	0.2618453301758412	[699,545]	[831,1103,867]	3	hSpCas9	negative selection	5341092
119955169	119955191	1	+	27760321	HT29	viability after 10 days	CATGTTGCACCCTTGCGACAGG	NOTCH2	ENSG00000134250	-0.255648890744211	[419,327]	[468,408,297]	-3	hSpCas9	negative selection	5341093
119963626	119963648	1	+	27760321	HT29	viability after 10 days	GCGACCATCGTTCAGGCAAGGG	NOTCH2	ENSG00000134250	0.3952791059334344	[570,445]	[724,783,990]	5	hSpCas9	negative selection	5341094
119965501	119965523	1	-	27760321	HT29	viability after 10 days	AGTACTCCGTGTCTGAATGGGG	NOTCH2	ENSG00000134250	-0.3147545037065419	[385,300]	[503,266,262]	-4	hSpCas9	negative selection	5341095
119937886	119937908	1	+	27760321	MOLM13	viability	ACATTGGGCACGTCACAATAGG	NOTCH2	ENSG00000134250	-0.4323398637611562	[237,195]	[139,47]	-3	hSpCas9	negative selection	5424554
119955127	119955149	1	-	27760321	MOLM13	viability	TCCGCTGTATATGCCCCGAGGG	NOTCH2	ENSG00000134250	0.3340642896967816	[947,699]	[597,565]	2	hSpCas9	negative selection	5424555
119955169	119955191	1	+	27760321	MOLM13	viability	CATGTTGCACCCTTGCGACAGG	NOTCH2	ENSG00000134250	0.0409786677631644	[464,419]	[254,257]	0	hSpCas9	negative selection	5424556
119963626	119963648	1	+	27760321	MOLM13	viability	GCGACCATCGTTCAGGCAAGGG	NOTCH2	ENSG00000134250	1.0724197529524147	[700,570]	[659,827]	7	hSpCas9	negative selection	5424557
119965501	119965523	1	-	27760321	MOLM13	viability	AGTACTCCGTGTCTGAATGGGG	NOTCH2	ENSG00000134250	0.769646520345005	[372,385]	[497,254]	5	hSpCas9	negative selection	5424558
120069531	120069554	1	+	27661255	K562	viability	GGCGCTACGCTCCGAAGCCCAGG	NOTCH2	ENSG00000134250	0.1629458059125133	[449,486]	[473,370]	5	dCas9-KRAB	negative selection	5497092
120068912	120068935	1	-	27661255	K562	viability	GATTCTGGCGTGGAGAGCGGGGG	NOTCH2	ENSG00000134250	0.09892356331142671	[1331,1205]	[1194,995]	3	dCas9-KRAB	negative selection	5497094
120068953	120068976	1	-	27661255	K562	viability	GCCGACGGCGGGCCTCGGAGGGG	NOTCH2	ENSG00000134250	-3.118979550481682	[310,367]	[42,20]	-9	dCas9-KRAB	negative selection	5497097
120069020	120069043	1	-	27661255	K562	viability	GTGCCAGGGTGCAGGGAGGTGGG	NOTCH2	ENSG00000134250	0.20084450381512725	[719,787]	[783,611]	7	dCas9-KRAB	negative selection	5497101
120069548	120069571	1	-	27661255	K562	viability	GAGTCGAGGCATTTGCGCCTGGG	NOTCH2	ENSG00000134250	0.02170282600733897	[1155,1220]	[951,971]	0	dCas9-KRAB	negative selection	5497102
119997300	119997323	1	+	27260156	BXPC3	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.04200118811706055	[1714]	[1746,1818,1751,2094]	0	hSpCas9	negative selection	5558458
119986950	119986973	1	+	27260156	BXPC3	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	-0.028982507275553404	[1229]	[1162,1205,1186,1521]	0	hSpCas9	negative selection	5558459
119987030	119987053	1	-	27260156	BXPC3	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.19394088570188428	[1289]	[990,1069,1245,1464]	-4	hSpCas9	negative selection	5558460
120005419	120005442	1	+	27260156	BXPC3	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.42817475615050693	[121]	[122,89,93,64]	-7	hSpCas9	negative selection	5622715
119997114	119997137	1	-	27260156	BXPC3	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.09496240584040427	[833]	[798,839,1139,967]	2	hSpCas9	negative selection	5622716
120005391	120005414	1	-	27260156	BXPC3	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.00939910706840874	[164]	[196,148,157,189]	0	hSpCas9	negative selection	5622717
119997300	119997323	1	+	27260156	A673	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.11719997043486141	[1714]	[2508,2215,1945,2296]	3	hSpCas9	negative selection	5679709
119986950	119986973	1	+	27260156	A673	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.2144799470130141	[1229]	[1830,1612,1771,1646]	5	hSpCas9	negative selection	5679710
119987030	119987053	1	-	27260156	A673	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.010422797338335732	[1289]	[1640,1622,1377,1515]	0	hSpCas9	negative selection	5679711
120005419	120005442	1	+	27260156	A673	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.09785537675089406	[121]	[224,128,114,85]	-2	hSpCas9	negative selection	5743966
119997114	119997137	1	-	27260156	A673	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.022495703448622617	[833]	[967,893,1118,1085]	0	hSpCas9	negative selection	5743967
120005391	120005414	1	-	27260156	A673	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.30117632169045305	[164]	[286,218,226,248]	7	hSpCas9	negative selection	5743968
119997300	119997323	1	+	27260156	A375	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	-0.008153404883062265	[1714]	[1805,2235,2123,1843]	0	hSpCas9	negative selection	5800960
119986950	119986973	1	+	27260156	A375	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.14008744085571734	[1229]	[1440,1845,1280,1770]	2	hSpCas9	negative selection	5800961
119987030	119987053	1	-	27260156	A375	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.05340054498374158	[1289]	[1808,1429,1509,1490]	0	hSpCas9	negative selection	5800962
120005419	120005442	1	+	27260156	A375	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.019282311398262975	[121]	[110,198,185,80]	0	hSpCas9	negative selection	5865217
119997114	119997137	1	-	27260156	A375	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.43722108905431156	[833]	[1531,1300,1268,1183]	6	hSpCas9	negative selection	5865218
120005391	120005414	1	-	27260156	A375	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.7081199049771153	[164]	[201,261,489,297]	9	hSpCas9	negative selection	5865219
119997300	119997323	1	+	27260156	COLO741	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.03760856336998719	[1714]	[2628,2037,2116]	0	hSpCas9	negative selection	5922211
119986950	119986973	1	+	27260156	COLO741	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.32236057211102565	[1229]	[1774,2175,1926]	6	hSpCas9	negative selection	5922212
119987030	119987053	1	-	27260156	COLO741	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.19464040161524232	[1289]	[1816,1973,1859]	4	hSpCas9	negative selection	5922213
120005419	120005442	1	+	27260156	COLO741	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.635660066009387	[121]	[191,38,78]	-8	hSpCas9	negative selection	5986468
119997114	119997137	1	-	27260156	COLO741	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.18800445690342005	[833]	[1313,1086,1243]	4	hSpCas9	negative selection	5986469
120005391	120005414	1	-	27260156	COLO741	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.19784359086437786	[164]	[121,253,331]	4	hSpCas9	negative selection	5986470
119997300	119997323	1	+	27260156	CAL120	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	-0.43531324060017296	[1714]	[1717,1059,1969]	-6	hSpCas9	negative selection	6043462
119986950	119986973	1	+	27260156	CAL120	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.19682366446963306	[1229]	[1660,1932,1655]	3	hSpCas9	negative selection	6043463
119987030	119987053	1	-	27260156	CAL120	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.09131233926470106	[1289]	[1587,1827,1122]	-1	hSpCas9	negative selection	6043464
120005419	120005442	1	+	27260156	CAL120	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	0.1086865248174349	[121]	[286,138,84]	1	hSpCas9	negative selection	6107719
119997114	119997137	1	-	27260156	CAL120	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.339394014159613	[833]	[1671,1304,1020]	5	hSpCas9	negative selection	6107720
120005391	120005414	1	-	27260156	CAL120	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.3520380761892925	[164]	[403,283,121]	5	hSpCas9	negative selection	6107721
119997300	119997323	1	+	27260156	CADOES1	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	-0.031535796603293864	[1714]	[1549,1454,1829,1400]	0	hSpCas9	negative selection	6164713
119986950	119986973	1	+	27260156	CADOES1	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.26091758876354754	[1229]	[1456,1376,1400,1242]	4	hSpCas9	negative selection	6164714
119987030	119987053	1	-	27260156	CADOES1	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.1356514071912398	[1289]	[940,944,1273,1212]	-2	hSpCas9	negative selection	6164715
120005419	120005442	1	+	27260156	CADOES1	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	0.062467862002988594	[121]	[152,124,99,94]	1	hSpCas9	negative selection	6228970
119997114	119997137	1	-	27260156	CADOES1	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.19600661433440547	[833]	[920,988,738,905]	3	hSpCas9	negative selection	6228971
120005391	120005414	1	-	27260156	CADOES1	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.44709640420483265	[164]	[239,236,69,292]	7	hSpCas9	negative selection	6228972
119997300	119997323	1	+	27260156	EWS502	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.3939695924811044	[1714]	[1984,2336,2677,2608]	7	hSpCas9	negative selection	6285964
119986950	119986973	1	+	27260156	EWS502	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.3008582646647713	[1229]	[1221,1669,1821,1756]	5	hSpCas9	negative selection	6285965
119987030	119987053	1	-	27260156	EWS502	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.15545504868332682	[1289]	[1405,1398,1565,1745]	2	hSpCas9	negative selection	6285966
120005419	120005442	1	+	27260156	EWS502	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.0077617077521645594	[121]	[72,122,108,221]	0	hSpCas9	negative selection	6350221
119997114	119997137	1	-	27260156	EWS502	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.37627760036291114	[833]	[1112,959,1260,1269]	6	hSpCas9	negative selection	6350222
120005391	120005414	1	-	27260156	EWS502	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.3235097754664489	[164]	[138,316,178,245]	5	hSpCas9	negative selection	6350223
119997300	119997323	1	+	27260156	EW8	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.21826123238398143	[1714]	[1588,1627,1452,1816]	4	hSpCas9	negative selection	6407215
119986950	119986973	1	+	27260156	EW8	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.2412717026820126	[1229]	[1398,1275,981,1110]	4	hSpCas9	negative selection	6407216
119987030	119987053	1	-	27260156	EW8	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.012093158854161734	[1289]	[995,1015,1042,1082]	0	hSpCas9	negative selection	6407217
120005419	120005442	1	+	27260156	EW8	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-1.0617939484827876	[121]	[40,48,74,18]	-9	hSpCas9	negative selection	6471472
119997114	119997137	1	-	27260156	EW8	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.0627997270595746	[833]	[923,635,668,622]	1	hSpCas9	negative selection	6471473
120005391	120005414	1	-	27260156	EW8	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.38302136358361216	[164]	[196,87,56,85]	-6	hSpCas9	negative selection	6471474
119997300	119997323	1	+	27260156	CORL105	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.06058675665238278	[1714]	[2165,1747,2351,2157]	1	hSpCas9	negative selection	6528466
119986950	119986973	1	+	27260156	CORL105	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.05666265769915335	[1229]	[1256,1622,1692,1436]	1	hSpCas9	negative selection	6528467
119987030	119987053	1	-	27260156	CORL105	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.4581263013729977	[1289]	[1143,1066,1073,1109]	-7	hSpCas9	negative selection	6528468
120005419	120005442	1	+	27260156	CORL105	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.8601521525735039	[121]	[78,93,81,59]	-9	hSpCas9	negative selection	6592723
119997114	119997137	1	-	27260156	CORL105	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	-0.0897704846032985	[833]	[1036,776,1140,756]	-2	hSpCas9	negative selection	6592724
120005391	120005414	1	-	27260156	CORL105	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.22498665759596315	[164]	[194,167,151,144]	-4	hSpCas9	negative selection	6592725
119997300	119997323	1	+	27260156	HS294T	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.5929266848592634	[1714]	[864,964,1059,1145]	7	hSpCas9	negative selection	6649717
119986950	119986973	1	+	27260156	HS294T	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.25418105685077386	[1229]	[346,567,767,612]	3	hSpCas9	negative selection	6649718
119987030	119987053	1	-	27260156	HS294T	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.19785329415971775	[1289]	[421,446,358,525]	-3	hSpCas9	negative selection	6649719
120005419	120005442	1	+	27260156	HS294T	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-1.299157468730773	[121]	[10,34,5,25]	-9	hSpCas9	negative selection	6713974
119997114	119997137	1	-	27260156	HS294T	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	-0.05952615073137135	[833]	[220,301,360,371]	-1	hSpCas9	negative selection	6713975
120005391	120005414	1	-	27260156	HS294T	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.5468337664119882	[164]	[36,40,54,41]	-7	hSpCas9	negative selection	6713976
119997300	119997323	1	+	27260156	HCC44	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	-0.4537691785767892	[1714]	[1218,1253,1336,1820]	-6	hSpCas9	negative selection	6770968
119986950	119986973	1	+	27260156	HCC44	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.1365637390617893	[1229]	[1867,1215,1690,1435]	2	hSpCas9	negative selection	6770969
119987030	119987053	1	-	27260156	HCC44	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.388903524219943	[1289]	[1139,1058,1319,978]	-6	hSpCas9	negative selection	6770970
120005419	120005442	1	+	27260156	HCC44	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-2.0171324089553377	[121]	[60,21,20,33]	-9	hSpCas9	negative selection	6835225
119997114	119997137	1	-	27260156	HCC44	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.20494420233502608	[833]	[1013,1079,1507,813]	3	hSpCas9	negative selection	6835226
120005391	120005414	1	-	27260156	HCC44	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.1446801622378595	[164]	[156,96,293,156]	-2	hSpCas9	negative selection	6835227
119997300	119997323	1	+	27260156	G402	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.23390076188005526	[1714]	[2303,2775,2416,2338]	3	hSpCas9	negative selection	6892219
119986950	119986973	1	+	27260156	G402	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.48783369985011404	[1229]	[3348,1582,2180,1477]	6	hSpCas9	negative selection	6892220
119987030	119987053	1	-	27260156	G402	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.11751642919859862	[1289]	[1908,1922,1123,1899]	1	hSpCas9	negative selection	6892221
120005419	120005442	1	+	27260156	G402	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	0.9343129805224246	[121]	[232,169,80,621]	9	hSpCas9	negative selection	6956476
119997114	119997137	1	-	27260156	G402	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.415248489367273	[833]	[1872,1078,995,1524]	5	hSpCas9	negative selection	6956477
120005391	120005414	1	-	27260156	G402	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.6763089135674107	[164]	[189,220,340,499]	8	hSpCas9	negative selection	6956478
119997300	119997323	1	+	27260156	L33	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	-0.2509124195998589	[1714]	[1266,547,1073,1456]	-5	hSpCas9	negative selection	7013470
119986950	119986973	1	+	27260156	L33	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.21586821977071202	[1229]	[1262,598,848,1639]	5	hSpCas9	negative selection	7013471
119987030	119987053	1	-	27260156	L33	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.4971316020981049	[1289]	[728,453,554,939]	-8	hSpCas9	negative selection	7013472
120005419	120005442	1	+	27260156	L33	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.6452107565371574	[121]	[51,18,74,94]	-9	hSpCas9	negative selection	7077727
119997114	119997137	1	-	27260156	L33	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	-0.023843552116928013	[833]	[942,326,466,793]	0	hSpCas9	negative selection	7077728
120005391	120005414	1	-	27260156	L33	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.249168625515237	[164]	[206,67,119,219]	5	hSpCas9	negative selection	7077729
119997300	119997323	1	+	27260156	K562	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.40154393390034215	[1714]	[2017,2404,2118,1564]	5	hSpCas9	negative selection	7134721
119986950	119986973	1	+	27260156	K562	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.1040613137127464	[1229]	[1412,1288,1173,872]	1	hSpCas9	negative selection	7134722
119987030	119987053	1	-	27260156	K562	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.45056751747480317	[1289]	[931,895,880,668]	-5	hSpCas9	negative selection	7134723
120005419	120005442	1	+	27260156	K562	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.4980180040902611	[121]	[50,104,122,31]	-5	hSpCas9	negative selection	7198978
119997114	119997137	1	-	27260156	K562	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.3754903757741723	[833]	[1011,956,632,1208]	5	hSpCas9	negative selection	7198979
120005391	120005414	1	-	27260156	K562	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.11791867875823869	[164]	[191,131,200,30]	-1	hSpCas9	negative selection	7198980
119997300	119997323	1	+	27260156	HT29	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.31041671464753406	[1714]	[2436,2676,2855,2374]	6	hSpCas9	negative selection	7255972
119986950	119986973	1	+	27260156	HT29	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.18596650923349345	[1229]	[1582,1864,1725,1630]	3	hSpCas9	negative selection	7255973
119987030	119987053	1	-	27260156	HT29	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.0368794978360063	[1289]	[1673,1749,1348,1378]	0	hSpCas9	negative selection	7255974
120005419	120005442	1	+	27260156	HT29	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	0.08359108403679705	[121]	[158,242,120,116]	1	hSpCas9	negative selection	7320229
119997114	119997137	1	-	27260156	HT29	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.061731543469020767	[833]	[1260,1040,968,977]	1	hSpCas9	negative selection	7320230
120005391	120005414	1	-	27260156	HT29	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.09232591844462834	[164]	[254,275,150,183]	1	hSpCas9	negative selection	7320231
119997300	119997323	1	+	27260156	MHHES1	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.2679450460806603	[1714]	[2762,2556,2202,1901]	5	hSpCas9	negative selection	7377223
119986950	119986973	1	+	27260156	MHHES1	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.1377392967981388	[1229]	[1962,1777,1273,1199]	2	hSpCas9	negative selection	7377224
119987030	119987053	1	-	27260156	MHHES1	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.07012203637281833	[1289]	[1450,1805,1506,1359]	1	hSpCas9	negative selection	7377225
120005419	120005442	1	+	27260156	MHHES1	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.18137755712706172	[121]	[91,202,184,28]	-3	hSpCas9	negative selection	7441480
119997114	119997137	1	-	27260156	MHHES1	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.2845097513579593	[833]	[1478,1491,1228,563]	5	hSpCas9	negative selection	7441481
120005391	120005414	1	-	27260156	MHHES1	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.018166931927299235	[164]	[297,175,214,93]	0	hSpCas9	negative selection	7441482
119997300	119997323	1	+	27260156	MEWO	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.28095665598033914	[1714]	[2627,1618,1733]	6	hSpCas9	negative selection	7498474
119986950	119986973	1	+	27260156	MEWO	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.23337456220280184	[1229]	[1557,1111,1428]	5	hSpCas9	negative selection	7498475
119987030	119987053	1	-	27260156	MEWO	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.08823098524468942	[1289]	[1568,1095,1239]	2	hSpCas9	negative selection	7498476
120005419	120005442	1	+	27260156	MEWO	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.24198105176509976	[121]	[150,111,36]	-5	hSpCas9	negative selection	7562731
119997114	119997137	1	-	27260156	MEWO	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.04831230764898242	[833]	[796,889,730]	1	hSpCas9	negative selection	7562732
120005391	120005414	1	-	27260156	MEWO	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.15146865387628594	[164]	[149,206,152]	3	hSpCas9	negative selection	7562733
119997300	119997323	1	+	27260156	LNCAPCLONEFGC	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	-0.24301565935415503	[1714]	[1229,1345,1424,1264]	-4	hSpCas9	negative selection	7619725
119986950	119986973	1	+	27260156	LNCAPCLONEFGC	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	-0.04605769067521592	[1229]	[1067,880,1069,1308]	0	hSpCas9	negative selection	7619726
119987030	119987053	1	-	27260156	LNCAPCLONEFGC	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.289842415458226	[1289]	[870,818,1194,983]	-4	hSpCas9	negative selection	7619727
120005419	120005442	1	+	27260156	LNCAPCLONEFGC	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.948273425974345	[121]	[58,65,60,42]	-8	hSpCas9	negative selection	7683982
119997114	119997137	1	-	27260156	LNCAPCLONEFGC	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.27449567784847617	[833]	[1068,732,936,927]	4	hSpCas9	negative selection	7683983
120005391	120005414	1	-	27260156	LNCAPCLONEFGC	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.1340097472456201	[164]	[152,80,155,160]	-2	hSpCas9	negative selection	7683984
119997300	119997323	1	+	27260156	PANC0327	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.02903806840941625	[1714]	[1798,1380,1688,1390]	0	hSpCas9	negative selection	7740976
119986950	119986973	1	+	27260156	PANC0327	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.19725552486813713	[1229]	[1314,1247,1172,1279]	3	hSpCas9	negative selection	7740977
119987030	119987053	1	-	27260156	PANC0327	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.02589077650108207	[1289]	[1261,1105,1174,1138]	0	hSpCas9	negative selection	7740978
120005419	120005442	1	+	27260156	PANC0327	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.7851821993819685	[121]	[29,84,73,56]	-8	hSpCas9	negative selection	7805233
119997114	119997137	1	-	27260156	PANC0327	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.2439831842449336	[833]	[817,839,855,994]	3	hSpCas9	negative selection	7805234
120005391	120005414	1	-	27260156	PANC0327	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.5754097388186624	[164]	[153,85,121,522]	8	hSpCas9	negative selection	7805235
119997300	119997323	1	+	27260156	NCIH2009	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.2539963862438084	[1714]	[2872,2934,2760]	3	hSpCas9	negative selection	7862227
119986950	119986973	1	+	27260156	NCIH2009	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.3619552611095955	[1229]	[2360,2046,2246]	5	hSpCas9	negative selection	7862228
119987030	119987053	1	-	27260156	NCIH2009	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.10175408132252084	[1289]	[2201,1702,1950]	1	hSpCas9	negative selection	7862229
120005419	120005442	1	+	27260156	NCIH2009	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-1.2102610018211184	[121]	[78,69,72]	-8	hSpCas9	negative selection	7926484
119997114	119997137	1	-	27260156	NCIH2009	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.4533886396113933	[833]	[2162,1426,1308]	6	hSpCas9	negative selection	7926485
120005391	120005414	1	-	27260156	NCIH2009	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.2299201644743265	[164]	[226,217,357]	3	hSpCas9	negative selection	7926486
119997300	119997323	1	+	27260156	NCIH1373	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	-0.02469242294106011	[1714]	[2383,1892,1787,404]	0	hSpCas9	negative selection	7983478
119986950	119986973	1	+	27260156	NCIH1373	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.44207376185910996	[1229]	[2271,1570,1896,481]	4	hSpCas9	negative selection	7983479
119987030	119987053	1	-	27260156	NCIH1373	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.03601445065906406	[1289]	[1977,1140,1255,440]	0	hSpCas9	negative selection	7983480
120005419	120005442	1	+	27260156	NCIH1373	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-3.4171100653689264	[121]	[7,15,3,5]	-9	hSpCas9	negative selection	8047735
119997114	119997137	1	-	27260156	NCIH1373	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	-0.03854605614155482	[833]	[764,938,871,273]	0	hSpCas9	negative selection	8047736
120005391	120005414	1	-	27260156	NCIH1373	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.32629829536425947	[164]	[302,353,192,16]	3	hSpCas9	negative selection	8047737
119997300	119997323	1	+	27260156	PATU8902	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.4296731485184293	[1714]	[3458,3249,2785,3488]	4	hSpCas9	negative selection	8104729
119986950	119986973	1	+	27260156	PATU8902	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.11571198145049122	[1229]	[2174,2412,1383,1516]	1	hSpCas9	negative selection	8104730
119987030	119987053	1	-	27260156	PATU8902	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.09817101671326767	[1289]	[2588,1702,1524,1957]	1	hSpCas9	negative selection	8104731
120005419	120005442	1	+	27260156	PATU8902	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.892458415365978	[121]	[46,174,51,103]	-7	hSpCas9	negative selection	8168986
119997114	119997137	1	-	27260156	PATU8902	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.3046445118038259	[833]	[1458,1817,872,1762]	3	hSpCas9	negative selection	8168987
120005391	120005414	1	-	27260156	PATU8902	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.4210126563158212	[164]	[553,244,179,274]	4	hSpCas9	negative selection	8168988
119997300	119997323	1	+	27260156	PANC1	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	-0.0575358177977674	[1714]	[1479,1681,1476,1104]	-1	hSpCas9	negative selection	8225980
119986950	119986973	1	+	27260156	PANC1	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.23744158190361508	[1229]	[1207,1449,1234,1129]	4	hSpCas9	negative selection	8225981
119987030	119987053	1	-	27260156	PANC1	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.061955076920503505	[1289]	[1291,1024,1070,860]	-1	hSpCas9	negative selection	8225982
120005419	120005442	1	+	27260156	PANC1	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.5620701575048228	[121]	[133,47,54,43]	-7	hSpCas9	negative selection	8290237
119997114	119997137	1	-	27260156	PANC1	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.14714751878324706	[833]	[647,939,797,804]	2	hSpCas9	negative selection	8290238
120005391	120005414	1	-	27260156	PANC1	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.09999491019756945	[164]	[158,81,169,108]	-2	hSpCas9	negative selection	8290239
119997300	119997323	1	+	27260156	PANC0813	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	-0.026476702798108098	[1714]	[2116,2188,1561,2046]	0	hSpCas9	negative selection	8347231
119986950	119986973	1	+	27260156	PANC0813	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.20173832486726573	[1229]	[2028,1431,1924,1312]	3	hSpCas9	negative selection	8347232
119987030	119987053	1	-	27260156	PANC0813	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.06714249888724311	[1289]	[2060,1451,1534,1355]	1	hSpCas9	negative selection	8347233
120005419	120005442	1	+	27260156	PANC0813	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.6160769581918686	[121]	[148,56,114,59]	-7	hSpCas9	negative selection	8411488
119997114	119997137	1	-	27260156	PANC0813	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.017157730229190427	[833]	[900,1045,955,1048]	0	hSpCas9	negative selection	8411489
120005391	120005414	1	-	27260156	PANC0813	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.3679103782872084	[164]	[184,161,131,125]	-5	hSpCas9	negative selection	8411490
119997300	119997323	1	+	27260156	RDES	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.4167062255020091	[1714]	[2262,2251,3055,3079]	6	hSpCas9	negative selection	8468482
119986950	119986973	1	+	27260156	RDES	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.006638680042857059	[1229]	[1204,1183,1635,1742]	0	hSpCas9	negative selection	8468483
119987030	119987053	1	-	27260156	RDES	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.2240681282599295	[1289]	[1040,1205,1492,1382]	-4	hSpCas9	negative selection	8468484
120005419	120005442	1	+	27260156	RDES	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.3504772367246125	[121]	[97,125,75,140]	-5	hSpCas9	negative selection	8532739
119997114	119997137	1	-	27260156	RDES	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.3078896134953799	[833]	[920,1296,1223,1342]	5	hSpCas9	negative selection	8532740
120005391	120005414	1	-	27260156	RDES	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.6269363100179751	[164]	[282,252,371,257]	8	hSpCas9	negative selection	8532741
119997300	119997323	1	+	27260156	PC3	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.14358946955543406	[1714]	[1304,1884,3137,1760]	3	hSpCas9	negative selection	8589733
119986950	119986973	1	+	27260156	PC3	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.1750518210214942	[1229]	[845,1194,2872,1316]	4	hSpCas9	negative selection	8589734
119987030	119987053	1	-	27260156	PC3	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.036264907026280824	[1289]	[885,1180,1858,1358]	-1	hSpCas9	negative selection	8589735
120005419	120005442	1	+	27260156	PC3	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.6950874481688292	[121]	[52,32,226,49]	-9	hSpCas9	negative selection	8653990
119997114	119997137	1	-	27260156	PC3	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.043278732181189605	[833]	[654,686,1374,912]	1	hSpCas9	negative selection	8653991
120005391	120005414	1	-	27260156	PC3	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.08158015913975492	[164]	[99,122,218,217]	-2	hSpCas9	negative selection	8653992
119997300	119997323	1	+	27260156	PATU8988T	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.35243871787607617	[1714]	[2000,2258,1673,2585]	6	hSpCas9	negative selection	8710984
119986950	119986973	1	+	27260156	PATU8988T	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.26104789370138115	[1229]	[1681,1897,1065,1071]	4	hSpCas9	negative selection	8710985
119987030	119987053	1	-	27260156	PATU8988T	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.3635894737685974	[1289]	[1456,1438,1518,2018]	6	hSpCas9	negative selection	8710986
120005419	120005442	1	+	27260156	PATU8988T	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.9386943073268132	[121]	[23,58,53,112]	-8	hSpCas9	negative selection	8775241
119997114	119997137	1	-	27260156	PATU8988T	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.1422348116993587	[833]	[899,1127,800,739]	2	hSpCas9	negative selection	8775242
120005391	120005414	1	-	27260156	PATU8988T	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.25380039902811014	[164]	[173,126,96,136]	-4	hSpCas9	negative selection	8775243
119997300	119997323	1	+	27260156	T47D	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.1463286372030148	[1714]	[2183,2052,2360,2258]	3	hSpCas9	negative selection	8832235
119986950	119986973	1	+	27260156	T47D	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.08400865328003415	[1229]	[1493,1395,1552,1645]	1	hSpCas9	negative selection	8832236
119987030	119987053	1	-	27260156	T47D	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.11516160084976335	[1289]	[1709,1445,1693,1676]	2	hSpCas9	negative selection	8832237
120005419	120005442	1	+	27260156	T47D	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.43334877450351783	[121]	[105,93,111,109]	-7	hSpCas9	negative selection	8896492
119997114	119997137	1	-	27260156	T47D	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.1680934316827173	[833]	[1195,1026,1014,1136]	3	hSpCas9	negative selection	8896493
120005391	120005414	1	-	27260156	T47D	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.32220910392585567	[164]	[214,191,237,322]	6	hSpCas9	negative selection	8896494
119997300	119997323	1	+	27260156	SU8686	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.3609873319719159	[1714]	[1799,2090,2429,2513]	6	hSpCas9	negative selection	8953486
119986950	119986973	1	+	27260156	SU8686	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.15916129790520372	[1229]	[1200,1190,1519,1609]	2	hSpCas9	negative selection	8953487
119987030	119987053	1	-	27260156	SU8686	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	0.00023835427016005717	[1289]	[1146,1114,1305,1633]	0	hSpCas9	negative selection	8953488
120005419	120005442	1	+	27260156	SU8686	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-1.2375804576937797	[121]	[75,18,68,40]	-9	hSpCas9	negative selection	9017743
119997114	119997137	1	-	27260156	SU8686	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.029053781079266372	[833]	[815,846,837,874]	0	hSpCas9	negative selection	9017744
120005391	120005414	1	-	27260156	SU8686	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.0035823209131180533	[164]	[149,72,182,277]	0	hSpCas9	negative selection	9017745
119997300	119997323	1	+	27260156	SKES1	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.2079884596444379	[1714]	[2254,2333,1681,1727]	4	hSpCas9	negative selection	9074737
119986950	119986973	1	+	27260156	SKES1	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.07828226204855993	[1229]	[1527,1368,1180,1149]	1	hSpCas9	negative selection	9074738
119987030	119987053	1	-	27260156	SKES1	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.03132524519476121	[1289]	[1411,1391,1250,1032]	0	hSpCas9	negative selection	9074739
120005419	120005442	1	+	27260156	SKES1	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.670070482344574	[121]	[48,159,46,57]	-9	hSpCas9	negative selection	9138994
119997114	119997137	1	-	27260156	SKES1	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.1396747474276917	[833]	[1111,919,828,833]	3	hSpCas9	negative selection	9138995
120005391	120005414	1	-	27260156	SKES1	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.3797459614803005	[164]	[163,321,232,148]	7	hSpCas9	negative selection	9138996
119997300	119997323	1	+	27260156	TOV112D	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.28239894702841006	[1714]	[2615,2828,1400,1742]	5	hSpCas9	negative selection	9195988
119986950	119986973	1	+	27260156	TOV112D	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.2458677165980001	[1229]	[1462,1442,1230,1692]	5	hSpCas9	negative selection	9195989
119987030	119987053	1	-	27260156	TOV112D	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.10532434853503814	[1289]	[1408,1581,995,933]	-2	hSpCas9	negative selection	9195990
120005419	120005442	1	+	27260156	TOV112D	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	0.08581254776097902	[121]	[159,98,142,111]	1	hSpCas9	negative selection	9260245
119997114	119997137	1	-	27260156	TOV112D	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.12465339109569618	[833]	[995,1128,698,878]	2	hSpCas9	negative selection	9260246
120005391	120005414	1	-	27260156	TOV112D	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.7332252731049509	[164]	[181,427,340,179]	9	hSpCas9	negative selection	9260247
119997300	119997323	1	+	27260156	TC71	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.038754539416853806	[1714]	[1914,1788,1934,1913]	1	hSpCas9	negative selection	9317239
119986950	119986973	1	+	27260156	TC71	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.24495180520991822	[1229]	[1725,1714,1354,1449]	6	hSpCas9	negative selection	9317240
119987030	119987053	1	-	27260156	TC71	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.10752407646235018	[1289]	[1275,1448,1110,1304]	-3	hSpCas9	negative selection	9317241
120005419	120005442	1	+	27260156	TC71	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.95709013787042	[121]	[67,59,75,64]	-9	hSpCas9	negative selection	9381496
119997114	119997137	1	-	27260156	TC71	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	-0.10556998283837993	[833]	[975,777,781,782]	-3	hSpCas9	negative selection	9381497
120005391	120005414	1	-	27260156	TC71	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	0.16764565159428213	[164]	[197,169,273,146]	4	hSpCas9	negative selection	9381498
119997300	119997323	1	+	27260156	TC32	viability	ACAGGCAGGCATCCGTCCATTGG	NOTCH2	ENSG00000134250	0.2455305607620213	[1714]	[1806,1538,2449,1980]	4	hSpCas9	negative selection	9438490
119986950	119986973	1	+	27260156	TC32	viability	CTGTACATACCTGTCCATTGTGG	NOTCH2	ENSG00000134250	0.09886825712668545	[1229]	[1121,936,1618,1403]	1	hSpCas9	negative selection	9438491
119987030	119987053	1	-	27260156	TC32	viability	TTGATGACTGCCCTAACCACAGG	NOTCH2	ENSG00000134250	-0.34807521154731735	[1289]	[893,642,1256,1148]	-6	hSpCas9	negative selection	9438492
120005419	120005442	1	+	27260156	TC32	viability	ATGGATGAGATGTTGAGTACTGG	NOTCH2	ENSG00000134250	-0.6445410854883908	[121]	[34,59,83,124]	-8	hSpCas9	negative selection	9502747
119997114	119997137	1	-	27260156	TC32	viability	CTACCAGTGCCAGTGCCCTCAGG	NOTCH2	ENSG00000134250	0.27192815543658666	[833]	[891,692,1163,1130]	5	hSpCas9	negative selection	9502748
120005391	120005414	1	-	27260156	TC32	viability	GTGTCTCGACCCTGCCTGAATGG	NOTCH2	ENSG00000134250	-0.1530740205196699	[164]	[117,54,198,228]	-3	hSpCas9	negative selection	9502749
119965476	119965499	1	-	27869803	HPAFII	viability after 27 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.06625243614762855	[254]	[111,163,NaN]	0	hSpCas9	negative selection	9528382
119966367	119966390	1	+	27869803	HPAFII	viability after 27 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-0.8702673819375251	[109]	[47,17,NaN]	-6	hSpCas9	negative selection	9528383
119967513	119967536	1	+	27869803	HPAFII	viability after 27 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	0.47418101891344777	[178]	[169,97,NaN]	4	hSpCas9	negative selection	9528384
119968114	119968137	1	+	27869803	HPAFII	viability after 27 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.6004157111221942	[68]	[84,29,NaN]	5	hSpCas9	negative selection	9528385
119969569	119969592	1	+	27869803	HPAFII	viability after 27 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.5860470892037485	[228]	[357,32,NaN]	5	hSpCas9	negative selection	9528386
119987019	119987042	1	-	27869803	HPAFII	viability after 27 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	1.0841213476914136	[302]	[304,364,NaN]	8	hSpCas9	negative selection	9528388
119965476	119965499	1	-	27869803	HPAFII	viability after 15 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	-0.10292510545368477	[254]	[277,240,NaN]	-1	hSpCas9	negative selection	9610831
119966367	119966390	1	+	27869803	HPAFII	viability after 15 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-1.0895409877916118	[109]	[86,35,NaN]	-8	hSpCas9	negative selection	9610832
119967513	119967536	1	+	27869803	HPAFII	viability after 15 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	0.19456570894711156	[178]	[414,98,NaN]	2	hSpCas9	negative selection	9610833
119968114	119968137	1	+	27869803	HPAFII	viability after 15 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	1.3643027272185337	[68]	[193,188,NaN]	9	hSpCas9	negative selection	9610834
119969569	119969592	1	+	27869803	HPAFII	viability after 15 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.21394564736811061	[228]	[520,138,NaN]	2	hSpCas9	negative selection	9610835
119987019	119987042	1	-	27869803	HPAFII	viability after 15 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	0.7685525770611384	[302]	[756,428,NaN]	8	hSpCas9	negative selection	9610837
119965476	119965499	1	-	27869803	ASPC1	viability after 36 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	-0.3810424070219648	[586]	[209,185,95]	-4	hSpCas9	negative selection	9693280
119966367	119966390	1	+	27869803	ASPC1	viability after 36 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-0.2724613528016022	[280]	[117,62,68]	-3	hSpCas9	negative selection	9693281
119967513	119967536	1	+	27869803	ASPC1	viability after 36 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	-0.5115544157573202	[564]	[174,193,66]	-5	hSpCas9	negative selection	9693282
119968114	119968137	1	+	27869803	ASPC1	viability after 36 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.7906457363194268	[299]	[265,205,99]	7	hSpCas9	negative selection	9693283
119969569	119969592	1	+	27869803	ASPC1	viability after 36 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	-0.43363354250774194	[513]	[259,15,134]	-4	hSpCas9	negative selection	9693284
119987019	119987042	1	-	27869803	ASPC1	viability after 36 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	-0.15820058764878037	[942]	[410,214,273]	-2	hSpCas9	negative selection	9693286
119965476	119965499	1	-	27869803	PATU8988S	viability after 35 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	-0.20500309741800765	[441]	[125,182,NaN]	-2	hSpCas9	negative selection	9775729
119966367	119966390	1	+	27869803	PATU8988S	viability after 35 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-1.1904158906932418	[183]	[19,44,NaN]	-8	hSpCas9	negative selection	9775730
119967513	119967536	1	+	27869803	PATU8988S	viability after 35 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	-0.16949204707440613	[453]	[197,126,NaN]	-2	hSpCas9	negative selection	9775731
119968114	119968137	1	+	27869803	PATU8988S	viability after 35 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.45276477970333806	[278]	[281,24,NaN]	5	hSpCas9	negative selection	9775732
119969569	119969592	1	+	27869803	PATU8988S	viability after 35 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	-1.4286381016566696	[500]	[55,93,NaN]	-8	hSpCas9	negative selection	9775733
119987019	119987042	1	-	27869803	PATU8988S	viability after 35 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	0.2225081288658366	[777]	[405,324,NaN]	2	hSpCas9	negative selection	9775735
119965476	119965499	1	-	27869803	PATU8988S	viability after 31 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	0.2355715724210432	[441]	[137,295,NaN]	3	hSpCas9	negative selection	9858178
119966367	119966390	1	+	27869803	PATU8988S	viability after 31 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-0.5476226815545753	[183]	[25,80,NaN]	-6	hSpCas9	negative selection	9858179
119967513	119967536	1	+	27869803	PATU8988S	viability after 31 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	-0.5459113680930572	[453]	[112,137,NaN]	-5	hSpCas9	negative selection	9858180
119968114	119968137	1	+	27869803	PATU8988S	viability after 31 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.08121354630935096	[278]	[173,45,NaN]	1	hSpCas9	negative selection	9858181
119969569	119969592	1	+	27869803	PATU8988S	viability after 31 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	-0.8933526170092446	[500]	[52,176,NaN]	-7	hSpCas9	negative selection	9858182
119987019	119987042	1	-	27869803	PATU8988S	viability after 31 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	-0.22538607282036477	[777]	[234,303,NaN]	-3	hSpCas9	negative selection	9858184
119965476	119965499	1	-	27869803	HPAFII	viability after 35 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	-0.8145722637337097	[254]	[47,101,NaN]	-5	hSpCas9	negative selection	9940627
119966367	119966390	1	+	27869803	HPAFII	viability after 35 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-1.3667870275243	[109]	[30,10,NaN]	-6	hSpCas9	negative selection	9940628
119967513	119967536	1	+	27869803	HPAFII	viability after 35 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	0.5083945007172861	[178]	[166,85,NaN]	3	hSpCas9	negative selection	9940629
119968114	119968137	1	+	27869803	HPAFII	viability after 35 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.3122409111741946	[68]	[80,0,NaN]	2	hSpCas9	negative selection	9940630
119969569	119969592	1	+	27869803	HPAFII	viability after 35 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.8788788502181635	[228]	[358,48,NaN]	6	hSpCas9	negative selection	9940631
119987019	119987042	1	-	27869803	HPAFII	viability after 35 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	0.8082130800414492	[302]	[285,248,NaN]	5	hSpCas9	negative selection	9940633
119965476	119965499	1	-	27869803	HPAFII	viability after 31 days	AAGTGTATCGATCACCCGAATGG	NOTCH2	ENSG00000134250	-0.1685698635719961	[254]	[89,167,NaN]	-1	hSpCas9	negative selection	10023076
119966367	119966390	1	+	27869803	HPAFII	viability after 31 days	GGCACTTACCAGGAGGACACAGG	NOTCH2	ENSG00000134250	-1.7302038736284977	[109]	[20,15,NaN]	-7	hSpCas9	negative selection	10023077
119967513	119967536	1	+	27869803	HPAFII	viability after 31 days	TTGATGTCCATCTCACAACGAGG	NOTCH2	ENSG00000134250	1.095781799624441	[178]	[263,160,NaN]	7	hSpCas9	negative selection	10023078
119968114	119968137	1	+	27869803	HPAFII	viability after 31 days	CCCTTTGTAGCCTTGTGGGCAGG	NOTCH2	ENSG00000134250	0.7333554013073693	[68]	[83,42,NaN]	5	hSpCas9	negative selection	10023079
119969569	119969592	1	+	27869803	HPAFII	viability after 31 days	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.5263284965615257	[228]	[298,60,NaN]	4	hSpCas9	negative selection	10023080
119987019	119987042	1	-	27869803	HPAFII	viability after 31 days	CCTAACCACAGGTGTCAGAATGG	NOTCH2	ENSG00000134250	1.2256044052925334	[302]	[378,417,NaN]	8	hSpCas9	negative selection	10023082
119925702	119925725	1	+	28162770	P31FUJ	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-3.785343227443157	[175]	[14]	-9	hSpCas9	negative selection	10201473
119925776	119925799	1	-	28162770	P31FUJ	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.22136730935209492	[376]	[379]	-2	hSpCas9	negative selection	10201474
119925567	119925590	1	+	28162770	P31FUJ	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	0.07104543584762735	[545]	[673]	0	hSpCas9	negative selection	10201475
119920279	119920302	1	+	28162770	P31FUJ	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-0.8311852208978563	[161]	[106]	-6	hSpCas9	negative selection	10201476
119969569	119969592	1	+	28162770	P31FUJ	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.48246831865250867	[200]	[329]	5	hSpCas9	negative selection	10201477
119940693	119940716	1	+	28162770	P31FUJ	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	1.439623137557117	[79]	[254]	9	hSpCas9	negative selection	10201478
119937846	119937869	1	+	28162770	P31FUJ	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	-0.19668277860772665	[354]	[363]	-2	hSpCas9	negative selection	10201479
119937369	119937392	1	+	28162770	P31FUJ	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	-0.4826173212161985	[477]	[401]	-4	hSpCas9	negative selection	10201480
119929152	119929175	1	-	28162770	P31FUJ	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	0.9395133444529278	[66]	[150]	9	hSpCas9	negative selection	10201481
119926554	119926577	1	-	28162770	P31FUJ	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	0.14643457343661853	[305]	[397]	1	hSpCas9	negative selection	10201482
119925702	119925725	1	+	28162770	TF1	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10370839
119925776	119925799	1	-	28162770	TF1	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	NaN	[NaN]	[111]	1	hSpCas9	negative selection	10370840
119925567	119925590	1	+	28162770	TF1	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	NaN	[NaN]	[468]	1	hSpCas9	negative selection	10370841
119920279	119920302	1	+	28162770	TF1	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10370842
119969569	119969592	1	+	28162770	TF1	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	NaN	[NaN]	[470]	1	hSpCas9	negative selection	10370843
119940693	119940716	1	+	28162770	TF1	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10370844
119937846	119937869	1	+	28162770	TF1	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	NaN	[NaN]	[178]	1	hSpCas9	negative selection	10370845
119937369	119937392	1	+	28162770	TF1	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	NaN	[NaN]	[451]	1	hSpCas9	negative selection	10370846
119929152	119929175	1	-	28162770	TF1	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	NaN	[NaN]	[51]	1	hSpCas9	negative selection	10370847
119926554	119926577	1	-	28162770	TF1	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	NaN	[NaN]	[313]	1	hSpCas9	negative selection	10370848
119925702	119925725	1	+	28162770	SKM1	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-2.479113984498997	[40]	[12]	-9	hSpCas9	negative selection	10540205
119925776	119925799	1	-	28162770	SKM1	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.16234183002324828	[68]	[108]	-1	hSpCas9	negative selection	10540206
119925567	119925590	1	+	28162770	SKM1	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	-0.03447340555976086	[156]	[270]	0	hSpCas9	negative selection	10540207
119920279	119920302	1	+	28162770	SKM1	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-2.8220016980220057	[59]	[14]	-9	hSpCas9	negative selection	10540208
119969569	119969592	1	+	28162770	SKM1	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	-0.17814550824728065	[63]	[99]	-1	hSpCas9	negative selection	10540209
119940693	119940716	1	+	28162770	SKM1	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	0.1779983019779945	[19]	[39]	1	hSpCas9	negative selection	10540210
119937846	119937869	1	+	28162770	SKM1	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	0.372170849666984	[58]	[134]	3	hSpCas9	negative selection	10540211
119937369	119937392	1	+	28162770	SKM1	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	0.33180363805702995	[119]	[266]	3	hSpCas9	negative selection	10540212
119929152	119929175	1	-	28162770	SKM1	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	0.722318818201805	[23]	[69]	7	hSpCas9	negative selection	10540213
119926554	119926577	1	-	28162770	SKM1	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	0.6902044602638366	[60]	[173]	6	hSpCas9	negative selection	10540214
119925702	119925725	1	+	28162770	SKM1	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-2.479113984498997	[40]	[12]	-9	hSpCas9	negative selection	10709571
119925776	119925799	1	-	28162770	SKM1	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.16234183002324828	[68]	[108]	-1	hSpCas9	negative selection	10709572
119925567	119925590	1	+	28162770	SKM1	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	-0.03447340555976086	[156]	[270]	0	hSpCas9	negative selection	10709573
119920279	119920302	1	+	28162770	SKM1	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-2.8220016980220057	[59]	[14]	-9	hSpCas9	negative selection	10709574
119969569	119969592	1	+	28162770	SKM1	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	-0.17814550824728065	[63]	[99]	-1	hSpCas9	negative selection	10709575
119940693	119940716	1	+	28162770	SKM1	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	0.1779983019779945	[19]	[39]	1	hSpCas9	negative selection	10709576
119937846	119937869	1	+	28162770	SKM1	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	0.372170849666984	[58]	[134]	3	hSpCas9	negative selection	10709577
119937369	119937392	1	+	28162770	SKM1	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	0.33180363805702995	[119]	[266]	3	hSpCas9	negative selection	10709578
119929152	119929175	1	-	28162770	SKM1	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	0.722318818201805	[23]	[69]	7	hSpCas9	negative selection	10709579
119926554	119926577	1	-	28162770	SKM1	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	0.6902044602638366	[60]	[173]	6	hSpCas9	negative selection	10709580
119925702	119925725	1	+	28162770	PL21	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-2.0093137511396293	[147]	[15]	-8	hSpCas9	negative selection	10878937
119925776	119925799	1	-	28162770	PL21	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	1.9866253444993252	[188]	[325]	9	hSpCas9	negative selection	10878938
119925567	119925590	1	+	28162770	PL21	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	-0.5476733619138785	[533]	[158]	-4	hSpCas9	negative selection	10878939
119920279	119920302	1	+	28162770	PL21	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-1.809320714759746	[152]	[18]	-8	hSpCas9	negative selection	10878940
119969569	119969592	1	+	28162770	PL21	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.04541701969067813	[235]	[105]	0	hSpCas9	negative selection	10878941
119940693	119940716	1	+	28162770	PL21	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	1.2631494120151205	[111]	[116]	9	hSpCas9	negative selection	10878942
119937846	119937869	1	+	28162770	PL21	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	-0.35658920550289214	[252]	[85]	-3	hSpCas9	negative selection	10878943
119937369	119937392	1	+	28162770	PL21	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	-0.592831389405628	[498]	[143]	-4	hSpCas9	negative selection	10878944
119929152	119929175	1	-	28162770	PL21	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	0.3521427079343702	[53]	[29]	3	hSpCas9	negative selection	10878945
119926554	119926577	1	-	28162770	PL21	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	-0.07231980413374234	[214]	[88]	0	hSpCas9	negative selection	10878946
119925702	119925725	1	+	28162770	P31FUJ	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-3.785343227443157	[175]	[14]	-9	hSpCas9	negative selection	11048303
119925776	119925799	1	-	28162770	P31FUJ	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.22136730935209492	[376]	[379]	-2	hSpCas9	negative selection	11048304
119925567	119925590	1	+	28162770	P31FUJ	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	0.07104543584762735	[545]	[673]	0	hSpCas9	negative selection	11048305
119920279	119920302	1	+	28162770	P31FUJ	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-0.8311852208978563	[161]	[106]	-6	hSpCas9	negative selection	11048306
119969569	119969592	1	+	28162770	P31FUJ	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.48246831865250867	[200]	[329]	5	hSpCas9	negative selection	11048307
119940693	119940716	1	+	28162770	P31FUJ	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	1.439623137557117	[79]	[254]	9	hSpCas9	negative selection	11048308
119937846	119937869	1	+	28162770	P31FUJ	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	-0.19668277860772665	[354]	[363]	-2	hSpCas9	negative selection	11048309
119937369	119937392	1	+	28162770	P31FUJ	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	-0.4826173212161985	[477]	[401]	-4	hSpCas9	negative selection	11048310
119929152	119929175	1	-	28162770	P31FUJ	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	0.9395133444529278	[66]	[150]	9	hSpCas9	negative selection	11048311
119926554	119926577	1	-	28162770	P31FUJ	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	0.14643457343661853	[305]	[397]	1	hSpCas9	negative selection	11048312
119925702	119925725	1	+	28162770	OCIAML5	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-3.910960259917566	[74]	[8]	-9	hSpCas9	negative selection	11217669
119925776	119925799	1	-	28162770	OCIAML5	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.16778951622465124	[144]	[232]	-1	hSpCas9	negative selection	11217670
119925567	119925590	1	+	28162770	OCIAML5	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	0.32547161468819064	[293]	[664]	2	hSpCas9	negative selection	11217671
119920279	119920302	1	+	28162770	OCIAML5	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-1.0001652098531308	[81]	[73]	-6	hSpCas9	negative selection	11217672
119969569	119969592	1	+	28162770	OCIAML5	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.2785175389461474	[94]	[207]	2	hSpCas9	negative selection	11217673
119940693	119940716	1	+	28162770	OCIAML5	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	-1.2671040701428409	[87]	[65]	-6	hSpCas9	negative selection	11217674
119937846	119937869	1	+	28162770	OCIAML5	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	-0.14997143654484302	[200]	[326]	-1	hSpCas9	negative selection	11217675
119937369	119937392	1	+	28162770	OCIAML5	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	0.9796426806860226	[192]	[686]	8	hSpCas9	negative selection	11217676
119929152	119929175	1	-	28162770	OCIAML5	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	0.5724312576639132	[37]	[101]	5	hSpCas9	negative selection	11217677
119926554	119926577	1	-	28162770	OCIAML5	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	0.28109988056819757	[211]	[464]	2	hSpCas9	negative selection	11217678
119925702	119925725	1	+	28162770	EOL1	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-0.029282046996539413	[245]	[126]	0	hSpCas9	negative selection	11387035
119925776	119925799	1	-	28162770	EOL1	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.3416263417938265	[367]	[152]	-3	hSpCas9	negative selection	11387036
119925567	119925590	1	+	28162770	EOL1	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	0.4837518700624619	[922]	[679]	4	hSpCas9	negative selection	11387037
119920279	119920302	1	+	28162770	EOL1	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-3.2251993479341476	[354]	[19]	-9	hSpCas9	negative selection	11387038
119969569	119969592	1	+	28162770	EOL1	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	-0.3411857838642146	[427]	[177]	-3	hSpCas9	negative selection	11387039
119940693	119940716	1	+	28162770	EOL1	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	1.442503583794945	[212]	[304]	9	hSpCas9	negative selection	11387040
119937846	119937869	1	+	28162770	EOL1	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	-0.38030680995788624	[293]	[118]	-3	hSpCas9	negative selection	11387041
119937369	119937392	1	+	28162770	EOL1	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	0.898861127906885	[509]	[500]	7	hSpCas9	negative selection	11387042
119929152	119929175	1	-	28162770	EOL1	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	-0.6393531136227919	[67]	[22]	-4	hSpCas9	negative selection	11387043
119926554	119926577	1	-	28162770	EOL1	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	0.4320661868663423	[286]	[203]	4	hSpCas9	negative selection	11387044
119925702	119925725	1	+	28162770	MOLM13	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-2.153052416282144	[202]	[32]	-7	hSpCas9	negative selection	11556401
119925776	119925799	1	-	28162770	MOLM13	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.0788537969460871	[297]	[203]	0	hSpCas9	negative selection	11556402
119925567	119925590	1	+	28162770	MOLM13	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	0.7382033688244016	[625]	[754]	5	hSpCas9	negative selection	11556403
119920279	119920302	1	+	28162770	MOLM13	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-3.645452091531366	[224]	[12]	-9	hSpCas9	negative selection	11556404
119969569	119969592	1	+	28162770	MOLM13	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	-0.11505958773892902	[357]	[238]	0	hSpCas9	negative selection	11556405
119940693	119940716	1	+	28162770	MOLM13	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	0.45884424194157175	[159]	[158]	3	hSpCas9	negative selection	11556406
119937846	119937869	1	+	28162770	MOLM13	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	0.30403657022178504	[325]	[290]	2	hSpCas9	negative selection	11556407
119937369	119937392	1	+	28162770	MOLM13	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	0.3017451197167905	[523]	[466]	2	hSpCas9	negative selection	11556408
119929152	119929175	1	-	28162770	MOLM13	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	-0.8316709003143292	[95]	[38]	-4	hSpCas9	negative selection	11556409
119926554	119926577	1	-	28162770	MOLM13	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	-0.1150763091126305	[360]	[240]	0	hSpCas9	negative selection	11556410
119925702	119925725	1	+	28162770	HEL	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-6.09872815440079	[213]	[1]	-9	hSpCas9	negative selection	11725767
119925776	119925799	1	-	28162770	HEL	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.6443592787239062	[265]	[108]	-4	hSpCas9	negative selection	11725768
119925567	119925590	1	+	28162770	HEL	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	0.7039596575685481	[668]	[697]	6	hSpCas9	negative selection	11725769
119920279	119920302	1	+	28162770	HEL	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-2.7243780366532606	[226]	[21]	-8	hSpCas9	negative selection	11725770
119969569	119969592	1	+	28162770	HEL	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.7234073918749561	[312]	[330]	6	hSpCas9	negative selection	11725771
119940693	119940716	1	+	28162770	HEL	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	-0.20873864328955516	[165]	[91]	-1	hSpCas9	negative selection	11725772
119937846	119937869	1	+	28162770	HEL	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	0.4161803810843559	[288]	[246]	3	hSpCas9	negative selection	11725773
119937369	119937392	1	+	28162770	HEL	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	0.436018568846238	[411]	[356]	3	hSpCas9	negative selection	11725774
119929152	119929175	1	-	28162770	HEL	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	0.1452391725295401	[47]	[33]	1	hSpCas9	negative selection	11725775
119926554	119926577	1	-	28162770	HEL	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	0.5977290970827911	[292]	[283]	5	hSpCas9	negative selection	11725776
119925702	119925725	1	+	28162770	MV411	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	0.053059505615924096	[118]	[103]	0	hSpCas9	negative selection	11895133
119925776	119925799	1	-	28162770	MV411	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.06215974219386755	[232]	[187]	0	hSpCas9	negative selection	11895134
119925567	119925590	1	+	28162770	MV411	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	0.49997958279892685	[574]	[684]	4	hSpCas9	negative selection	11895135
119920279	119920302	1	+	28162770	MV411	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-4.5495754270533695	[138]	[4]	-9	hSpCas9	negative selection	11895136
119969569	119969592	1	+	28162770	MV411	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.1992284577401556	[212]	[205]	1	hSpCas9	negative selection	11895137
119940693	119940716	1	+	28162770	MV411	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	-0.24050049554351616	[114]	[81]	-2	hSpCas9	negative selection	11895138
119937846	119937869	1	+	28162770	MV411	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	-0.4123789446225942	[266]	[168]	-3	hSpCas9	negative selection	11895139
119937369	119937392	1	+	28162770	MV411	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	0.7929489007852081	[345]	[504]	7	hSpCas9	negative selection	11895140
119929152	119929175	1	-	28162770	MV411	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	0.3949947391966331	[64]	[71]	3	hSpCas9	negative selection	11895141
119926554	119926577	1	-	28162770	MV411	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	1.920878007163767	[194]	[621]	9	hSpCas9	negative selection	11895142
119925702	119925725	1	+	28162770	MONOMAC1	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-0.5690056244465116	[109]	[84]	-5	hSpCas9	negative selection	12064499
119925776	119925799	1	-	28162770	MONOMAC1	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.16687487654930128	[141]	[144]	-1	hSpCas9	negative selection	12064500
119925567	119925590	1	+	28162770	MONOMAC1	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	1.1676715666719926	[411]	[1060]	8	hSpCas9	negative selection	12064501
119920279	119920302	1	+	28162770	MONOMAC1	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-1.3748239662748365	[137]	[60]	-8	hSpCas9	negative selection	12064502
119969569	119969592	1	+	28162770	MONOMAC1	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	-0.328742526271376	[148]	[135]	-3	hSpCas9	negative selection	12064503
119940693	119940716	1	+	28162770	MONOMAC1	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	0.9203201035786049	[58]	[127]	8	hSpCas9	negative selection	12064504
119937846	119937869	1	+	28162770	MONOMAC1	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	1.2940587301973803	[126]	[356]	9	hSpCas9	negative selection	12064505
119937369	119937392	1	+	28162770	MONOMAC1	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	1.0972670001194562	[231]	[568]	8	hSpCas9	negative selection	12064506
119929152	119929175	1	-	28162770	MONOMAC1	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	-0.9340024412257597	[49]	[29]	-6	hSpCas9	negative selection	12064507
119926554	119926577	1	-	28162770	MONOMAC1	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	0.5452621914096931	[161]	[270]	5	hSpCas9	negative selection	12064508
119925702	119925725	1	+	28162770	OCIAML2	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-2.6570429494730425	[32]	[28]	-9	hSpCas9	negative selection	12233865
119925776	119925799	1	-	28162770	OCIAML2	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	-0.4908077071797915	[53]	[212]	-4	hSpCas9	negative selection	12233866
119925567	119925590	1	+	28162770	OCIAML2	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	0.48578090621015635	[104]	[814]	5	hSpCas9	negative selection	12233867
119920279	119920302	1	+	28162770	OCIAML2	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-2.5112718097395073	[35]	[34]	-8	hSpCas9	negative selection	12233868
119969569	119969592	1	+	28162770	OCIAML2	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.5535364858885911	[36]	[300]	5	hSpCas9	negative selection	12233869
119940693	119940716	1	+	28162770	OCIAML2	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	0.557567066588491	[18]	[154]	5	hSpCas9	negative selection	12233870
119937846	119937869	1	+	28162770	OCIAML2	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	0.06810965871834933	[36]	[214]	0	hSpCas9	negative selection	12233871
119937369	119937392	1	+	28162770	OCIAML2	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	0.7949602854953892	[46]	[451]	7	hSpCas9	negative selection	12233872
119929152	119929175	1	-	28162770	OCIAML2	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	-0.011198206604863925	[11]	[65]	0	hSpCas9	negative selection	12233873
119926554	119926577	1	-	28162770	OCIAML2	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	0.33672509681544294	[50]	[356]	3	hSpCas9	negative selection	12233874
119925702	119925725	1	+	28162770	OCIAML3	viability	GGGGACTGGGGCAGAAGCAGCGG	NOTCH2	ENSG00000134250	-2.4977923250648604	[57]	[30]	-9	hSpCas9	negative selection	12403231
119925776	119925799	1	-	28162770	OCIAML3	viability	GCAAGGTGCCAGAGCAGCTGTGG	NOTCH2	ENSG00000134250	0.4659744645040693	[52]	[220]	4	hSpCas9	negative selection	12403232
119925567	119925590	1	+	28162770	OCIAML3	viability	GTGCCGTGTAGAGTTCACAGCGG	NOTCH2	ENSG00000134250	0.35528153934230366	[151]	[586]	3	hSpCas9	negative selection	12403233
119920279	119920302	1	+	28162770	OCIAML3	viability	GGAGGGGTGAGAGCCAGCGATGG	NOTCH2	ENSG00000134250	-1.3976104275206598	[47]	[54]	-7	hSpCas9	negative selection	12403234
119969569	119969592	1	+	28162770	OCIAML3	viability	GCCTGGAGTACAGGAGGCGAAGG	NOTCH2	ENSG00000134250	0.014801602351360854	[59]	[182]	0	hSpCas9	negative selection	12403235
119940693	119940716	1	+	28162770	OCIAML3	viability	CACAGGGCACAAGCAAGAGAAGG	NOTCH2	ENSG00000134250	1.7720130387463697	[28]	[298]	9	hSpCas9	negative selection	12403236
119937846	119937869	1	+	28162770	OCIAML3	viability	GCAAAGCTTACCTCTCCTGGAGG	NOTCH2	ENSG00000134250	-0.5865131037772389	[95]	[192]	-4	hSpCas9	negative selection	12403237
119937369	119937392	1	+	28162770	OCIAML3	viability	GTAGCTCCCAGTATAGCCCAGGG	NOTCH2	ENSG00000134250	-0.09777405819733864	[94]	[267]	0	hSpCas9	negative selection	12403238
119929152	119929175	1	-	28162770	OCIAML3	viability	GGTCCCCATTGCCTTAATGGTGG	NOTCH2	ENSG00000134250	1.4192891822892948	[26]	[217]	9	hSpCas9	negative selection	12403239
119926554	119926577	1	-	28162770	OCIAML3	viability	CAGATGCCCTGCCTGAATGGAGG	NOTCH2	ENSG00000134250	0.6711978645512576	[82]	[398]	6	hSpCas9	negative selection	12403240