Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 4855
• Symbol: NOTCH4
• Description: notch receptor 4

DataSource: http://genomecrispr.dkfz.de/#!/results/NOTCH4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
32211457	32211480	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Jiyoye	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000234876	0.7383812899812465	[154]	[194]	5	hSpCas9	negative selection	110245
32280209	32280232	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Jiyoye	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000223355	0.7383812899812465	[154]	[194]	5	hSpCas9	negative selection	110246
32203776	32203799	6	+	26472758	Jiyoye	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	0.7383812899812465	[154]	[194]	5	hSpCas9	negative selection	110247
32243166	32243189	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Jiyoye	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000232339	0.7383812899812465	[154]	[194]	5	hSpCas9	negative selection	110248
32161391	32161414	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Jiyoye	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000206312	0.7383812899812465	[154]	[194]	5	hSpCas9	negative selection	110249
32152255	32152278	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Jiyoye	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000235396	0.7383812899812465	[154]	[194]	5	hSpCas9	negative selection	110250
32270793	32270816	CHR_HSCHR6_MHC_APD_CTG1	+	26472758	Jiyoye	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000238196	0.7383812899812465	[154]	[194]	5	hSpCas9	negative selection	110251
32252545	32252568	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Jiyoye	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000232339	-0.4706527485001823	[214]	[116]	-3	hSpCas9	negative selection	110252
32289582	32289605	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Jiyoye	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000223355	-0.4706527485001823	[214]	[116]	-3	hSpCas9	negative selection	110253
32170763	32170786	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Jiyoye	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000206312	-0.4706527485001823	[214]	[116]	-3	hSpCas9	negative selection	110254
32213154	32213177	6	+	26472758	Jiyoye	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	-0.4706527485001823	[214]	[116]	-3	hSpCas9	negative selection	110255
32161618	32161641	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Jiyoye	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000235396	-0.4706527485001823	[214]	[116]	-3	hSpCas9	negative selection	110256
32220825	32220848	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Jiyoye	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000234876	-0.4706527485001823	[214]	[116]	-3	hSpCas9	negative selection	110257
32265673	32265696	CHR_HSCHR6_MHC_APD_CTG1	-	26472758	Jiyoye	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000238196	-3.857527844688539	[172]	[8]	-9	hSpCas9	negative selection	110258
32206337	32206360	CHR_HSCHR6_MHC_SSTO_CTG1	-	26472758	Jiyoye	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000234876	-3.857527844688539	[172]	[8]	-9	hSpCas9	negative selection	110259
32275089	32275112	CHR_HSCHR6_MHC_MCF_CTG1	-	26472758	Jiyoye	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000223355	-3.857527844688539	[172]	[8]	-9	hSpCas9	negative selection	110260
32198666	32198689	6	-	26472758	Jiyoye	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-3.857527844688539	[172]	[8]	-9	hSpCas9	negative selection	110261
32238051	32238074	CHR_HSCHR6_MHC_MANN_CTG1	-	26472758	Jiyoye	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000232339	-3.857527844688539	[172]	[8]	-9	hSpCas9	negative selection	110262
32156271	32156294	CHR_HSCHR6_MHC_QBL_CTG1	-	26472758	Jiyoye	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000206312	-3.857527844688539	[172]	[8]	-9	hSpCas9	negative selection	110263
32147135	32147158	CHR_HSCHR6_MHC_COX_CTG1	-	26472758	Jiyoye	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000235396	-3.857527844688539	[172]	[8]	-9	hSpCas9	negative selection	110264
32230332	32230355	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Jiyoye	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000234876	1.1480881601887423	[72]	[121]	7	hSpCas9	negative selection	110265
32180268	32180291	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Jiyoye	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000206312	1.1480881601887423	[72]	[121]	7	hSpCas9	negative selection	110266
32299105	32299128	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Jiyoye	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000223355	1.1480881601887423	[72]	[121]	7	hSpCas9	negative selection	110267
32262071	32262094	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Jiyoye	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000232339	1.1480881601887423	[72]	[121]	7	hSpCas9	negative selection	110268
32171119	32171142	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Jiyoye	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000235396	1.1480881601887423	[72]	[121]	7	hSpCas9	negative selection	110269
32222659	32222682	6	+	26472758	Jiyoye	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	1.1480881601887423	[72]	[121]	7	hSpCas9	negative selection	110270
32221208	32221231	6	+	26472758	Jiyoye	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	0.6234932884326372	[67]	[78]	4	hSpCas9	negative selection	110271
32178817	32178840	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Jiyoye	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000206312	0.6234932884326372	[67]	[78]	4	hSpCas9	negative selection	110272
32297657	32297680	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Jiyoye	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000223355	0.6234932884326372	[67]	[78]	4	hSpCas9	negative selection	110273
32260623	32260646	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Jiyoye	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000232339	0.6234932884326372	[67]	[78]	4	hSpCas9	negative selection	110274
32169671	32169694	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Jiyoye	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000235396	0.6234932884326372	[67]	[78]	4	hSpCas9	negative selection	110275
32228881	32228904	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Jiyoye	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000234876	0.6234932884326372	[67]	[78]	4	hSpCas9	negative selection	110276
32169577	32169600	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Jiyoye	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000235396	-2.939627382020518	[233]	[22]	-9	hSpCas9	negative selection	110277
32228787	32228810	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Jiyoye	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000234876	-2.939627382020518	[233]	[22]	-9	hSpCas9	negative selection	110278
32221114	32221137	6	+	26472758	Jiyoye	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-2.939627382020518	[233]	[22]	-9	hSpCas9	negative selection	110279
32178723	32178746	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Jiyoye	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000206312	-2.939627382020518	[233]	[22]	-9	hSpCas9	negative selection	110280
32297563	32297586	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Jiyoye	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000223355	-2.939627382020518	[233]	[22]	-9	hSpCas9	negative selection	110281
32260529	32260552	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Jiyoye	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000232339	-2.939627382020518	[233]	[22]	-9	hSpCas9	negative selection	110282
32220985	32221008	6	+	26472758	Jiyoye	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	-0.4566202348958154	[201]	[110]	-3	hSpCas9	negative selection	110283
32178594	32178617	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Jiyoye	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000206312	-0.4566202348958154	[201]	[110]	-3	hSpCas9	negative selection	110284
32297434	32297457	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Jiyoye	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000223355	-0.4566202348958154	[201]	[110]	-3	hSpCas9	negative selection	110285
32260400	32260423	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Jiyoye	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000232339	-0.4566202348958154	[201]	[110]	-3	hSpCas9	negative selection	110286
32169448	32169471	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Jiyoye	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000235396	-0.4566202348958154	[201]	[110]	-3	hSpCas9	negative selection	110287
32228658	32228681	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Jiyoye	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000234876	-0.4566202348958154	[201]	[110]	-3	hSpCas9	negative selection	110288
32259550	32259573	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Jiyoye	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000232339	0.14238051780764227	[327]	[272]	1	hSpCas9	negative selection	110289
32227808	32227831	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Jiyoye	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000234876	0.14238051780764227	[327]	[272]	1	hSpCas9	negative selection	110290
32220135	32220158	6	+	26472758	Jiyoye	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.14238051780764227	[327]	[272]	1	hSpCas9	negative selection	110291
32177744	32177767	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Jiyoye	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000206312	0.14238051780764227	[327]	[272]	1	hSpCas9	negative selection	110292
32168598	32168621	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Jiyoye	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000235396	0.14238051780764227	[327]	[272]	1	hSpCas9	negative selection	110293
32296584	32296607	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Jiyoye	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000223355	0.14238051780764227	[327]	[272]	1	hSpCas9	negative selection	110294
32256450	32256473	CHR_HSCHR6_MHC_MANN_CTG1	-	26472758	Jiyoye	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000232339	1.5023326145462135	[43]	[93]	8	hSpCas9	negative selection	110295
32217035	32217058	6	-	26472758	Jiyoye	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	1.5023326145462135	[43]	[93]	8	hSpCas9	negative selection	110296
32224708	32224731	CHR_HSCHR6_MHC_SSTO_CTG1	-	26472758	Jiyoye	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000234876	1.5023326145462135	[43]	[93]	8	hSpCas9	negative selection	110297
32174644	32174667	CHR_HSCHR6_MHC_QBL_CTG1	-	26472758	Jiyoye	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000206312	1.5023326145462135	[43]	[93]	8	hSpCas9	negative selection	110298
32165500	32165523	CHR_HSCHR6_MHC_COX_CTG1	-	26472758	Jiyoye	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000235396	1.5023326145462135	[43]	[93]	8	hSpCas9	negative selection	110299
32293484	32293507	CHR_HSCHR6_MHC_MCF_CTG1	-	26472758	Jiyoye	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000223355	1.5023326145462135	[43]	[93]	8	hSpCas9	negative selection	110300
32165420	32165443	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Jiyoye	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000235396	-0.48079800076001533	[160]	[86]	-3	hSpCas9	negative selection	110301
32174564	32174587	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Jiyoye	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000206312	-0.48079800076001533	[160]	[86]	-3	hSpCas9	negative selection	110302
32224628	32224651	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Jiyoye	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000234876	-0.48079800076001533	[160]	[86]	-3	hSpCas9	negative selection	110303
32216955	32216978	6	+	26472758	Jiyoye	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	-0.48079800076001533	[160]	[86]	-3	hSpCas9	negative selection	110304
32293404	32293427	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Jiyoye	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000223355	-0.48079800076001533	[160]	[86]	-3	hSpCas9	negative selection	110305
32256370	32256393	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Jiyoye	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000232339	-0.48079800076001533	[160]	[86]	-3	hSpCas9	negative selection	110306
32211457	32211480	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	KBM7	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000234876	0.1827948089338229	[577,475]	[329,234]	1	hSpCas9	negative selection	301363
32280209	32280232	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	KBM7	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000223355	0.1827948089338229	[577,475]	[329,234]	1	hSpCas9	negative selection	301364
32203776	32203799	6	+	26472758	KBM7	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	0.1827948089338229	[577,475]	[329,234]	1	hSpCas9	negative selection	301365
32243166	32243189	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	KBM7	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000232339	0.1827948089338229	[577,475]	[329,234]	1	hSpCas9	negative selection	301366
32161391	32161414	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	KBM7	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000206312	0.1827948089338229	[577,475]	[329,234]	1	hSpCas9	negative selection	301367
32152255	32152278	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	KBM7	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000235396	0.1827948089338229	[577,475]	[329,234]	1	hSpCas9	negative selection	301368
32270793	32270816	CHR_HSCHR6_MHC_APD_CTG1	+	26472758	KBM7	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000238196	0.1827948089338229	[577,475]	[329,234]	1	hSpCas9	negative selection	301369
32252545	32252568	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	KBM7	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000232339	0.20591114368028562	[762,636]	[368,385]	2	hSpCas9	negative selection	301370
32289582	32289605	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	KBM7	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000223355	0.20591114368028562	[762,636]	[368,385]	2	hSpCas9	negative selection	301371
32170763	32170786	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	KBM7	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000206312	0.20591114368028562	[762,636]	[368,385]	2	hSpCas9	negative selection	301372
32213154	32213177	6	+	26472758	KBM7	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	0.20591114368028562	[762,636]	[368,385]	2	hSpCas9	negative selection	301373
32161618	32161641	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	KBM7	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000235396	0.20591114368028562	[762,636]	[368,385]	2	hSpCas9	negative selection	301374
32220825	32220848	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	KBM7	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000234876	0.20591114368028562	[762,636]	[368,385]	2	hSpCas9	negative selection	301375
32265673	32265696	CHR_HSCHR6_MHC_APD_CTG1	-	26472758	KBM7	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000238196	-3.0672747179031794	[901,569]	[20,57]	-9	hSpCas9	negative selection	301376
32206337	32206360	CHR_HSCHR6_MHC_SSTO_CTG1	-	26472758	KBM7	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000234876	-3.0672747179031794	[901,569]	[20,57]	-9	hSpCas9	negative selection	301377
32275089	32275112	CHR_HSCHR6_MHC_MCF_CTG1	-	26472758	KBM7	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000223355	-3.0672747179031794	[901,569]	[20,57]	-9	hSpCas9	negative selection	301378
32198666	32198689	6	-	26472758	KBM7	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-3.0672747179031794	[901,569]	[20,57]	-9	hSpCas9	negative selection	301379
32238051	32238074	CHR_HSCHR6_MHC_MANN_CTG1	-	26472758	KBM7	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000232339	-3.0672747179031794	[901,569]	[20,57]	-9	hSpCas9	negative selection	301380
32156271	32156294	CHR_HSCHR6_MHC_QBL_CTG1	-	26472758	KBM7	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000206312	-3.0672747179031794	[901,569]	[20,57]	-9	hSpCas9	negative selection	301381
32147135	32147158	CHR_HSCHR6_MHC_COX_CTG1	-	26472758	KBM7	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000235396	-3.0672747179031794	[901,569]	[20,57]	-9	hSpCas9	negative selection	301382
32230332	32230355	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	KBM7	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000234876	0.5543860213562035	[741,443]	[524,289]	6	hSpCas9	negative selection	301383
32180268	32180291	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	KBM7	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000206312	0.5543860213562035	[741,443]	[524,289]	6	hSpCas9	negative selection	301384
32299105	32299128	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	KBM7	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000223355	0.5543860213562035	[741,443]	[524,289]	6	hSpCas9	negative selection	301385
32262071	32262094	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	KBM7	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000232339	0.5543860213562035	[741,443]	[524,289]	6	hSpCas9	negative selection	301386
32171119	32171142	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	KBM7	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000235396	0.5543860213562035	[741,443]	[524,289]	6	hSpCas9	negative selection	301387
32222659	32222682	6	+	26472758	KBM7	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	0.5543860213562035	[741,443]	[524,289]	6	hSpCas9	negative selection	301388
32221208	32221231	6	+	26472758	KBM7	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	0.8592203576528707	[394,263]	[187,355]	8	hSpCas9	negative selection	301389
32178817	32178840	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	KBM7	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000206312	0.8592203576528707	[394,263]	[187,355]	8	hSpCas9	negative selection	301390
32297657	32297680	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	KBM7	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000223355	0.8592203576528707	[394,263]	[187,355]	8	hSpCas9	negative selection	301391
32260623	32260646	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	KBM7	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000232339	0.8592203576528707	[394,263]	[187,355]	8	hSpCas9	negative selection	301392
32169671	32169694	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	KBM7	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000235396	0.8592203576528707	[394,263]	[187,355]	8	hSpCas9	negative selection	301393
32228881	32228904	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	KBM7	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000234876	0.8592203576528707	[394,263]	[187,355]	8	hSpCas9	negative selection	301394
32169577	32169600	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	KBM7	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000235396	-0.1679320230119642	[318,214]	[89,127]	-2	hSpCas9	negative selection	301395
32228787	32228810	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	KBM7	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000234876	-0.1679320230119642	[318,214]	[89,127]	-2	hSpCas9	negative selection	301396
32221114	32221137	6	+	26472758	KBM7	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-0.1679320230119642	[318,214]	[89,127]	-2	hSpCas9	negative selection	301397
32178723	32178746	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	KBM7	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000206312	-0.1679320230119642	[318,214]	[89,127]	-2	hSpCas9	negative selection	301398
32297563	32297586	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	KBM7	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000223355	-0.1679320230119642	[318,214]	[89,127]	-2	hSpCas9	negative selection	301399
32260529	32260552	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	KBM7	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000232339	-0.1679320230119642	[318,214]	[89,127]	-2	hSpCas9	negative selection	301400
32220985	32221008	6	+	26472758	KBM7	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	-0.5432542972681257	[930,941]	[278,325]	-5	hSpCas9	negative selection	301401
32178594	32178617	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	KBM7	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000206312	-0.5432542972681257	[930,941]	[278,325]	-5	hSpCas9	negative selection	301402
32297434	32297457	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	KBM7	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000223355	-0.5432542972681257	[930,941]	[278,325]	-5	hSpCas9	negative selection	301403
32260400	32260423	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	KBM7	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000232339	-0.5432542972681257	[930,941]	[278,325]	-5	hSpCas9	negative selection	301404
32169448	32169471	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	KBM7	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000235396	-0.5432542972681257	[930,941]	[278,325]	-5	hSpCas9	negative selection	301405
32228658	32228681	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	KBM7	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000234876	-0.5432542972681257	[930,941]	[278,325]	-5	hSpCas9	negative selection	301406
32259550	32259573	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	KBM7	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000232339	0.4198009278894923	[962,986]	[644,591]	4	hSpCas9	negative selection	301407
32227808	32227831	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	KBM7	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000234876	0.4198009278894923	[962,986]	[644,591]	4	hSpCas9	negative selection	301408
32220135	32220158	6	+	26472758	KBM7	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.4198009278894923	[962,986]	[644,591]	4	hSpCas9	negative selection	301409
32177744	32177767	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	KBM7	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000206312	0.4198009278894923	[962,986]	[644,591]	4	hSpCas9	negative selection	301410
32168598	32168621	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	KBM7	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000235396	0.4198009278894923	[962,986]	[644,591]	4	hSpCas9	negative selection	301411
32296584	32296607	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	KBM7	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000223355	0.4198009278894923	[962,986]	[644,591]	4	hSpCas9	negative selection	301412
32256450	32256473	CHR_HSCHR6_MHC_MANN_CTG1	-	26472758	KBM7	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000232339	-0.28835435622620154	[216,314]	[88,118]	-3	hSpCas9	negative selection	301413
32217035	32217058	6	-	26472758	KBM7	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	-0.28835435622620154	[216,314]	[88,118]	-3	hSpCas9	negative selection	301414
32224708	32224731	CHR_HSCHR6_MHC_SSTO_CTG1	-	26472758	KBM7	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000234876	-0.28835435622620154	[216,314]	[88,118]	-3	hSpCas9	negative selection	301415
32174644	32174667	CHR_HSCHR6_MHC_QBL_CTG1	-	26472758	KBM7	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000206312	-0.28835435622620154	[216,314]	[88,118]	-3	hSpCas9	negative selection	301416
32165500	32165523	CHR_HSCHR6_MHC_COX_CTG1	-	26472758	KBM7	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000235396	-0.28835435622620154	[216,314]	[88,118]	-3	hSpCas9	negative selection	301417
32293484	32293507	CHR_HSCHR6_MHC_MCF_CTG1	-	26472758	KBM7	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000223355	-0.28835435622620154	[216,314]	[88,118]	-3	hSpCas9	negative selection	301418
32165420	32165443	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	KBM7	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000235396	-0.5347917396666538	[438,470]	[140,155]	-5	hSpCas9	negative selection	301419
32174564	32174587	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	KBM7	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000206312	-0.5347917396666538	[438,470]	[140,155]	-5	hSpCas9	negative selection	301420
32224628	32224651	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	KBM7	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000234876	-0.5347917396666538	[438,470]	[140,155]	-5	hSpCas9	negative selection	301421
32216955	32216978	6	+	26472758	KBM7	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	-0.5347917396666538	[438,470]	[140,155]	-5	hSpCas9	negative selection	301422
32293404	32293427	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	KBM7	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000223355	-0.5347917396666538	[438,470]	[140,155]	-5	hSpCas9	negative selection	301423
32256370	32256393	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	KBM7	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000232339	-0.5347917396666538	[438,470]	[140,155]	-5	hSpCas9	negative selection	301424
32211457	32211480	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Raji	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000234876	0.5021010502728475	[285]	[93]	5	hSpCas9	negative selection	492481
32280209	32280232	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Raji	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000223355	0.5021010502728475	[285]	[93]	5	hSpCas9	negative selection	492482
32203776	32203799	6	+	26472758	Raji	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	0.5021010502728475	[285]	[93]	5	hSpCas9	negative selection	492483
32243166	32243189	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Raji	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000232339	0.5021010502728475	[285]	[93]	5	hSpCas9	negative selection	492484
32161391	32161414	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Raji	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000206312	0.5021010502728475	[285]	[93]	5	hSpCas9	negative selection	492485
32152255	32152278	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Raji	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000235396	0.5021010502728475	[285]	[93]	5	hSpCas9	negative selection	492486
32270793	32270816	CHR_HSCHR6_MHC_APD_CTG1	+	26472758	Raji	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000238196	0.5021010502728475	[285]	[93]	5	hSpCas9	negative selection	492487
32252545	32252568	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Raji	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000232339	-0.823353802189287	[487]	[63]	-6	hSpCas9	negative selection	492488
32289582	32289605	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Raji	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000223355	-0.823353802189287	[487]	[63]	-6	hSpCas9	negative selection	492489
32170763	32170786	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Raji	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000206312	-0.823353802189287	[487]	[63]	-6	hSpCas9	negative selection	492490
32213154	32213177	6	+	26472758	Raji	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	-0.823353802189287	[487]	[63]	-6	hSpCas9	negative selection	492491
32161618	32161641	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Raji	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000235396	-0.823353802189287	[487]	[63]	-6	hSpCas9	negative selection	492492
32220825	32220848	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Raji	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000234876	-0.823353802189287	[487]	[63]	-6	hSpCas9	negative selection	492493
32265673	32265696	CHR_HSCHR6_MHC_APD_CTG1	-	26472758	Raji	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000238196	-2.4683011517595457	[309]	[12]	-9	hSpCas9	negative selection	492494
32206337	32206360	CHR_HSCHR6_MHC_SSTO_CTG1	-	26472758	Raji	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000234876	-2.4683011517595457	[309]	[12]	-9	hSpCas9	negative selection	492495
32275089	32275112	CHR_HSCHR6_MHC_MCF_CTG1	-	26472758	Raji	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000223355	-2.4683011517595457	[309]	[12]	-9	hSpCas9	negative selection	492496
32198666	32198689	6	-	26472758	Raji	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-2.4683011517595457	[309]	[12]	-9	hSpCas9	negative selection	492497
32238051	32238074	CHR_HSCHR6_MHC_MANN_CTG1	-	26472758	Raji	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000232339	-2.4683011517595457	[309]	[12]	-9	hSpCas9	negative selection	492498
32156271	32156294	CHR_HSCHR6_MHC_QBL_CTG1	-	26472758	Raji	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000206312	-2.4683011517595457	[309]	[12]	-9	hSpCas9	negative selection	492499
32147135	32147158	CHR_HSCHR6_MHC_COX_CTG1	-	26472758	Raji	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000235396	-2.4683011517595457	[309]	[12]	-9	hSpCas9	negative selection	492500
32230332	32230355	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Raji	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000234876	0.009536211975454796	[243]	[56]	0	hSpCas9	negative selection	492501
32180268	32180291	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Raji	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000206312	0.009536211975454796	[243]	[56]	0	hSpCas9	negative selection	492502
32299105	32299128	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Raji	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000223355	0.009536211975454796	[243]	[56]	0	hSpCas9	negative selection	492503
32262071	32262094	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Raji	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000232339	0.009536211975454796	[243]	[56]	0	hSpCas9	negative selection	492504
32171119	32171142	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Raji	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000235396	0.009536211975454796	[243]	[56]	0	hSpCas9	negative selection	492505
32222659	32222682	6	+	26472758	Raji	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	0.009536211975454796	[243]	[56]	0	hSpCas9	negative selection	492506
32221208	32221231	6	+	26472758	Raji	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	0.17953332112943504	[155]	[40]	1	hSpCas9	negative selection	492507
32178817	32178840	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Raji	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000206312	0.17953332112943504	[155]	[40]	1	hSpCas9	negative selection	492508
32297657	32297680	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Raji	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000223355	0.17953332112943504	[155]	[40]	1	hSpCas9	negative selection	492509
32260623	32260646	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Raji	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000232339	0.17953332112943504	[155]	[40]	1	hSpCas9	negative selection	492510
32169671	32169694	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Raji	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000235396	0.17953332112943504	[155]	[40]	1	hSpCas9	negative selection	492511
32228881	32228904	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Raji	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000234876	0.17953332112943504	[155]	[40]	1	hSpCas9	negative selection	492512
32169577	32169600	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Raji	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000235396	-1.4451574876551794	[175]	[14]	-7	hSpCas9	negative selection	492513
32228787	32228810	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Raji	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000234876	-1.4451574876551794	[175]	[14]	-7	hSpCas9	negative selection	492514
32221114	32221137	6	+	26472758	Raji	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-1.4451574876551794	[175]	[14]	-7	hSpCas9	negative selection	492515
32178723	32178746	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Raji	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000206312	-1.4451574876551794	[175]	[14]	-7	hSpCas9	negative selection	492516
32297563	32297586	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Raji	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000223355	-1.4451574876551794	[175]	[14]	-7	hSpCas9	negative selection	492517
32260529	32260552	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Raji	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000232339	-1.4451574876551794	[175]	[14]	-7	hSpCas9	negative selection	492518
32220985	32221008	6	+	26472758	Raji	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	-0.6167417130191822	[521]	[78]	-5	hSpCas9	negative selection	492519
32178594	32178617	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Raji	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000206312	-0.6167417130191822	[521]	[78]	-5	hSpCas9	negative selection	492520
32297434	32297457	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Raji	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000223355	-0.6167417130191822	[521]	[78]	-5	hSpCas9	negative selection	492521
32260400	32260423	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Raji	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000232339	-0.6167417130191822	[521]	[78]	-5	hSpCas9	negative selection	492522
32169448	32169471	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Raji	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000235396	-0.6167417130191822	[521]	[78]	-5	hSpCas9	negative selection	492523
32228658	32228681	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Raji	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000234876	-0.6167417130191822	[521]	[78]	-5	hSpCas9	negative selection	492524
32259550	32259573	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Raji	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000232339	0.5311912442801754	[491]	[164]	5	hSpCas9	negative selection	492525
32227808	32227831	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Raji	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000234876	0.5311912442801754	[491]	[164]	5	hSpCas9	negative selection	492526
32220135	32220158	6	+	26472758	Raji	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.5311912442801754	[491]	[164]	5	hSpCas9	negative selection	492527
32177744	32177767	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Raji	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000206312	0.5311912442801754	[491]	[164]	5	hSpCas9	negative selection	492528
32168598	32168621	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Raji	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000235396	0.5311912442801754	[491]	[164]	5	hSpCas9	negative selection	492529
32296584	32296607	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Raji	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000223355	0.5311912442801754	[491]	[164]	5	hSpCas9	negative selection	492530
32256450	32256473	CHR_HSCHR6_MHC_MANN_CTG1	-	26472758	Raji	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000232339	-0.07481979584714954	[176]	[38]	0	hSpCas9	negative selection	492531
32217035	32217058	6	-	26472758	Raji	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	-0.07481979584714954	[176]	[38]	0	hSpCas9	negative selection	492532
32224708	32224731	CHR_HSCHR6_MHC_SSTO_CTG1	-	26472758	Raji	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000234876	-0.07481979584714954	[176]	[38]	0	hSpCas9	negative selection	492533
32174644	32174667	CHR_HSCHR6_MHC_QBL_CTG1	-	26472758	Raji	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000206312	-0.07481979584714954	[176]	[38]	0	hSpCas9	negative selection	492534
32165500	32165523	CHR_HSCHR6_MHC_COX_CTG1	-	26472758	Raji	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000235396	-0.07481979584714954	[176]	[38]	0	hSpCas9	negative selection	492535
32293484	32293507	CHR_HSCHR6_MHC_MCF_CTG1	-	26472758	Raji	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000223355	-0.07481979584714954	[176]	[38]	0	hSpCas9	negative selection	492536
32165420	32165443	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	Raji	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000235396	-0.2876792641439782	[262]	[49]	-2	hSpCas9	negative selection	492537
32174564	32174587	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	Raji	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000206312	-0.2876792641439782	[262]	[49]	-2	hSpCas9	negative selection	492538
32224628	32224651	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	Raji	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000234876	-0.2876792641439782	[262]	[49]	-2	hSpCas9	negative selection	492539
32216955	32216978	6	+	26472758	Raji	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	-0.2876792641439782	[262]	[49]	-2	hSpCas9	negative selection	492540
32293404	32293427	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	Raji	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000223355	-0.2876792641439782	[262]	[49]	-2	hSpCas9	negative selection	492541
32256370	32256393	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	Raji	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000232339	-0.2876792641439782	[262]	[49]	-2	hSpCas9	negative selection	492542
32211457	32211480	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	K562	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000234876	0.2330439378017898	[381]	[378]	1	hSpCas9	negative selection	683599
32280209	32280232	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	K562	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000223355	0.2330439378017898	[381]	[378]	1	hSpCas9	negative selection	683600
32203776	32203799	6	+	26472758	K562	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	0.2330439378017898	[381]	[378]	1	hSpCas9	negative selection	683601
32243166	32243189	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	K562	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000232339	0.2330439378017898	[381]	[378]	1	hSpCas9	negative selection	683602
32161391	32161414	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	K562	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000206312	0.2330439378017898	[381]	[378]	1	hSpCas9	negative selection	683603
32152255	32152278	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	K562	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000235396	0.2330439378017898	[381]	[378]	1	hSpCas9	negative selection	683604
32270793	32270816	CHR_HSCHR6_MHC_APD_CTG1	+	26472758	K562	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000238196	0.2330439378017898	[381]	[378]	1	hSpCas9	negative selection	683605
32252545	32252568	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	K562	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000232339	-0.005676622459848679	[665]	[559]	0	hSpCas9	negative selection	683606
32289582	32289605	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	K562	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000223355	-0.005676622459848679	[665]	[559]	0	hSpCas9	negative selection	683607
32170763	32170786	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	K562	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000206312	-0.005676622459848679	[665]	[559]	0	hSpCas9	negative selection	683608
32213154	32213177	6	+	26472758	K562	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	-0.005676622459848679	[665]	[559]	0	hSpCas9	negative selection	683609
32161618	32161641	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	K562	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000235396	-0.005676622459848679	[665]	[559]	0	hSpCas9	negative selection	683610
32220825	32220848	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	K562	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000234876	-0.005676622459848679	[665]	[559]	0	hSpCas9	negative selection	683611
32265673	32265696	CHR_HSCHR6_MHC_APD_CTG1	-	26472758	K562	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000238196	-6.73286119583347	[755]	[5]	-9	hSpCas9	negative selection	683612
32206337	32206360	CHR_HSCHR6_MHC_SSTO_CTG1	-	26472758	K562	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000234876	-6.73286119583347	[755]	[5]	-9	hSpCas9	negative selection	683613
32275089	32275112	CHR_HSCHR6_MHC_MCF_CTG1	-	26472758	K562	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000223355	-6.73286119583347	[755]	[5]	-9	hSpCas9	negative selection	683614
32198666	32198689	6	-	26472758	K562	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-6.73286119583347	[755]	[5]	-9	hSpCas9	negative selection	683615
32238051	32238074	CHR_HSCHR6_MHC_MANN_CTG1	-	26472758	K562	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000232339	-6.73286119583347	[755]	[5]	-9	hSpCas9	negative selection	683616
32156271	32156294	CHR_HSCHR6_MHC_QBL_CTG1	-	26472758	K562	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000206312	-6.73286119583347	[755]	[5]	-9	hSpCas9	negative selection	683617
32147135	32147158	CHR_HSCHR6_MHC_COX_CTG1	-	26472758	K562	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000235396	-6.73286119583347	[755]	[5]	-9	hSpCas9	negative selection	683618
32230332	32230355	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	K562	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000234876	-0.6245959601575861	[483]	[264]	-4	hSpCas9	negative selection	683619
32180268	32180291	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	K562	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000206312	-0.6245959601575861	[483]	[264]	-4	hSpCas9	negative selection	683620
32299105	32299128	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	K562	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000223355	-0.6245959601575861	[483]	[264]	-4	hSpCas9	negative selection	683621
32262071	32262094	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	K562	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000232339	-0.6245959601575861	[483]	[264]	-4	hSpCas9	negative selection	683622
32171119	32171142	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	K562	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000235396	-0.6245959601575861	[483]	[264]	-4	hSpCas9	negative selection	683623
32222659	32222682	6	+	26472758	K562	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	-0.6245959601575861	[483]	[264]	-4	hSpCas9	negative selection	683624
32221208	32221231	6	+	26472758	K562	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	0.09947039175534728	[271]	[245]	0	hSpCas9	negative selection	683625
32178817	32178840	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	K562	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000206312	0.09947039175534728	[271]	[245]	0	hSpCas9	negative selection	683626
32297657	32297680	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	K562	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000223355	0.09947039175534728	[271]	[245]	0	hSpCas9	negative selection	683627
32260623	32260646	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	K562	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000232339	0.09947039175534728	[271]	[245]	0	hSpCas9	negative selection	683628
32169671	32169694	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	K562	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000235396	0.09947039175534728	[271]	[245]	0	hSpCas9	negative selection	683629
32228881	32228904	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	K562	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000234876	0.09947039175534728	[271]	[245]	0	hSpCas9	negative selection	683630
32169577	32169600	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	K562	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000235396	-0.8900666045205736	[190]	[86]	-5	hSpCas9	negative selection	683631
32228787	32228810	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	K562	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000234876	-0.8900666045205736	[190]	[86]	-5	hSpCas9	negative selection	683632
32221114	32221137	6	+	26472758	K562	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-0.8900666045205736	[190]	[86]	-5	hSpCas9	negative selection	683633
32178723	32178746	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	K562	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000206312	-0.8900666045205736	[190]	[86]	-5	hSpCas9	negative selection	683634
32297563	32297586	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	K562	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000223355	-0.8900666045205736	[190]	[86]	-5	hSpCas9	negative selection	683635
32260529	32260552	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	K562	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000232339	-0.8900666045205736	[190]	[86]	-5	hSpCas9	negative selection	683636
32220985	32221008	6	+	26472758	K562	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	-1.7020759422932925	[793]	[205]	-7	hSpCas9	negative selection	683637
32178594	32178617	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	K562	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000206312	-1.7020759422932925	[793]	[205]	-7	hSpCas9	negative selection	683638
32297434	32297457	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	K562	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000223355	-1.7020759422932925	[793]	[205]	-7	hSpCas9	negative selection	683639
32260400	32260423	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	K562	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000232339	-1.7020759422932925	[793]	[205]	-7	hSpCas9	negative selection	683640
32169448	32169471	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	K562	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000235396	-1.7020759422932925	[793]	[205]	-7	hSpCas9	negative selection	683641
32228658	32228681	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	K562	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000234876	-1.7020759422932925	[793]	[205]	-7	hSpCas9	negative selection	683642
32259550	32259573	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	K562	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000232339	0.7710028795934483	[621]	[895]	6	hSpCas9	negative selection	683643
32227808	32227831	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	K562	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000234876	0.7710028795934483	[621]	[895]	6	hSpCas9	negative selection	683644
32220135	32220158	6	+	26472758	K562	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.7710028795934483	[621]	[895]	6	hSpCas9	negative selection	683645
32177744	32177767	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	K562	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000206312	0.7710028795934483	[621]	[895]	6	hSpCas9	negative selection	683646
32168598	32168621	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	K562	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000235396	0.7710028795934483	[621]	[895]	6	hSpCas9	negative selection	683647
32296584	32296607	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	K562	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000223355	0.7710028795934483	[621]	[895]	6	hSpCas9	negative selection	683648
32256450	32256473	CHR_HSCHR6_MHC_MANN_CTG1	-	26472758	K562	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000232339	0.17515606522933302	[191]	[182]	1	hSpCas9	negative selection	683649
32217035	32217058	6	-	26472758	K562	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	0.17515606522933302	[191]	[182]	1	hSpCas9	negative selection	683650
32224708	32224731	CHR_HSCHR6_MHC_SSTO_CTG1	-	26472758	K562	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000234876	0.17515606522933302	[191]	[182]	1	hSpCas9	negative selection	683651
32174644	32174667	CHR_HSCHR6_MHC_QBL_CTG1	-	26472758	K562	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000206312	0.17515606522933302	[191]	[182]	1	hSpCas9	negative selection	683652
32165500	32165523	CHR_HSCHR6_MHC_COX_CTG1	-	26472758	K562	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000235396	0.17515606522933302	[191]	[182]	1	hSpCas9	negative selection	683653
32293484	32293507	CHR_HSCHR6_MHC_MCF_CTG1	-	26472758	K562	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000223355	0.17515606522933302	[191]	[182]	1	hSpCas9	negative selection	683654
32165420	32165443	CHR_HSCHR6_MHC_COX_CTG1	+	26472758	K562	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000235396	-0.07228085241910437	[481]	[386]	0	hSpCas9	negative selection	683655
32174564	32174587	CHR_HSCHR6_MHC_QBL_CTG1	+	26472758	K562	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000206312	-0.07228085241910437	[481]	[386]	0	hSpCas9	negative selection	683656
32224628	32224651	CHR_HSCHR6_MHC_SSTO_CTG1	+	26472758	K562	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000234876	-0.07228085241910437	[481]	[386]	0	hSpCas9	negative selection	683657
32216955	32216978	6	+	26472758	K562	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	-0.07228085241910437	[481]	[386]	0	hSpCas9	negative selection	683658
32293404	32293427	CHR_HSCHR6_MHC_MCF_CTG1	+	26472758	K562	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000223355	-0.07228085241910437	[481]	[386]	0	hSpCas9	negative selection	683659
32256370	32256393	CHR_HSCHR6_MHC_MANN_CTG1	+	26472758	K562	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000232339	-0.07228085241910437	[481]	[386]	0	hSpCas9	negative selection	683660
32219747	32219770	6	+	26627737	DLD1	viability	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	0.6960446331503212	[246]	[192,163,33]	7	hSpCas9	negative selection	832264
32220258	32220281	6	+	26627737	DLD1	viability	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-0.3758751776215622	[432]	[55,54,186]	-4	hSpCas9	negative selection	832265
32220439	32220462	6	+	26627737	DLD1	viability	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	-2.3771408894789983	[37]	[4,0,0]	-9	hSpCas9	negative selection	832266
32221129	32221152	6	+	26627737	DLD1	viability	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	-0.12208127473132313	[1078]	[519,351,92]	-1	hSpCas9	negative selection	832267
32222644	32222667	6	+	26627737	DLD1	viability	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	-0.26199857658137593	[165]	[32,92,10]	-3	hSpCas9	negative selection	832268
32223009	32223032	6	+	26627737	DLD1	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	1.0990832937106207	[211]	[115,92,204]	8	hSpCas9	negative selection	832269
32219747	32219770	6	+	26627737	GBM cells	viability after 5 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	0.183367264354385	[233]	[140,143]	3	hSpCas9	negative selection	914579
32220258	32220281	6	+	26627737	GBM cells	viability after 5 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	0.3344154767242451	[209]	[149,133]	5	hSpCas9	negative selection	914580
32220439	32220462	6	+	26627737	GBM cells	viability after 5 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	1.0364173986356198	[14]	[22,9]	9	hSpCas9	negative selection	914581
32221129	32221152	6	+	26627737	GBM cells	viability after 5 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.3529028218637378	[337]	[201,260]	5	hSpCas9	negative selection	914582
32222644	32222667	6	+	26627737	GBM cells	viability after 5 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.11083296499262518	[157]	[109,72]	1	hSpCas9	negative selection	914583
32223009	32223032	6	+	26627737	GBM cells	viability after 5 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	1.0480053729108323	[123]	[144,129]	9	hSpCas9	negative selection	914584
32219747	32219770	6	+	26627737	GBM cells	viability after 13 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	0.4699640583049176	[233]	[230,130]	6	hSpCas9	negative selection	996894
32220258	32220281	6	+	26627737	GBM cells	viability after 13 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	0.4134802152637344	[209]	[148,153]	5	hSpCas9	negative selection	996895
32220439	32220462	6	+	26627737	GBM cells	viability after 13 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	-3.024787472030072	[14]	[0,0]	-9	hSpCas9	negative selection	996896
32221129	32221152	6	+	26627737	GBM cells	viability after 13 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.714808120928583	[337]	[359,252]	8	hSpCas9	negative selection	996897
32222644	32222667	6	+	26627737	GBM cells	viability after 13 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.22451045098972072	[157]	[76,118]	3	hSpCas9	negative selection	996898
32223009	32223032	6	+	26627737	GBM cells	viability after 13 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	1.009272760002584	[123]	[162,112]	9	hSpCas9	negative selection	996899
32219747	32219770	6	+	26627737	GBM cells	viability after 21 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	-0.02691420900945729	[233]	[129,119]	0	hSpCas9	negative selection	1079209
32220258	32220281	6	+	26627737	GBM cells	viability after 21 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	0.315170356332207	[209]	[154,129]	3	hSpCas9	negative selection	1079210
32220439	32220462	6	+	26627737	GBM cells	viability after 21 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	-1.7176104924022306	[14]	[2,1]	-8	hSpCas9	negative selection	1079211
32221129	32221152	6	+	26627737	GBM cells	viability after 21 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.9235865486834769	[337]	[340,354]	8	hSpCas9	negative selection	1079212
32222644	32222667	6	+	26627737	GBM cells	viability after 21 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	1.1465612419630984	[157]	[200,179]	9	hSpCas9	negative selection	1079213
32223009	32223032	6	+	26627737	GBM cells	viability after 21 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.8401230862415057	[123]	[129,111]	8	hSpCas9	negative selection	1079214
32219747	32219770	6	+	26627737	RPE1	viability after 9 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	-0.14836275832636306	[1023]	[228,366]	-1	hSpCas9	negative selection	1161524
32220258	32220281	6	+	26627737	RPE1	viability after 9 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-0.5467010967492348	[414]	[91,84]	-4	hSpCas9	negative selection	1161525
32220439	32220462	6	+	26627737	RPE1	viability after 9 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	0.6754465303148196	[1]	[0,0]	4	hSpCas9	negative selection	1161526
32221129	32221152	6	+	26627737	RPE1	viability after 9 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.3754908500026106	[1193]	[511,449]	2	hSpCas9	negative selection	1161527
32222644	32222667	6	+	26627737	RPE1	viability after 9 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	1.1738297866380216	[181]	[59,216]	7	hSpCas9	negative selection	1161528
32223009	32223032	6	+	26627737	RPE1	viability after 9 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-2.016370370460044	[873]	[71,61]	-8	hSpCas9	negative selection	1161529
32219747	32219770	6	+	26627737	RPE1	viability after 12 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	-0.13563322962492835	[1023]	[298,198]	-1	hSpCas9	negative selection	1243839
32220258	32220281	6	+	26627737	RPE1	viability after 12 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-1.113955450073774	[414]	[51,50]	-6	hSpCas9	negative selection	1243840
32220439	32220462	6	+	26627737	RPE1	viability after 12 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	1.467268112869264	[1]	[0,1]	7	hSpCas9	negative selection	1243841
32221129	32221152	6	+	26627737	RPE1	viability after 12 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.16316783026211745	[1193]	[348,369]	1	hSpCas9	negative selection	1243842
32222644	32222667	6	+	26627737	RPE1	viability after 12 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	1.3132988941552388	[181]	[36,210]	7	hSpCas9	negative selection	1243843
32223009	32223032	6	+	26627737	RPE1	viability after 12 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-1.6878138911699547	[873]	[68,76]	-8	hSpCas9	negative selection	1243844
32219747	32219770	6	+	26627737	RPE1	viability after 15 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	-0.41129507317279174	[1023]	[171,261]	-3	hSpCas9	negative selection	1326154
32220258	32220281	6	+	26627737	RPE1	viability after 15 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-1.9509166613151692	[414]	[37,22]	-8	hSpCas9	negative selection	1326155
32220439	32220462	6	+	26627737	RPE1	viability after 15 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	4.23750020001006	[1]	[0,19]	9	hSpCas9	negative selection	1326156
32221129	32221152	6	+	26627737	RPE1	viability after 15 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	-0.3462010283202103	[1193]	[338,194]	-2	hSpCas9	negative selection	1326157
32222644	32222667	6	+	26627737	RPE1	viability after 15 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	1.0847414327407137	[181]	[69,146]	6	hSpCas9	negative selection	1326158
32223009	32223032	6	+	26627737	RPE1	viability after 15 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-1.5727362283444477	[873]	[132,34]	-7	hSpCas9	negative selection	1326159
32219747	32219770	6	+	26627737	RPE1	viability after 18 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	-0.32295523157687744	[1023]	[203,238]	-2	hSpCas9	negative selection	1408469
32220258	32220281	6	+	26627737	RPE1	viability after 18 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-0.963058327632275	[414]	[55,58]	-6	hSpCas9	negative selection	1408470
32220439	32220462	6	+	26627737	RPE1	viability after 18 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	3.630048518679714	[1]	[11,0]	9	hSpCas9	negative selection	1408471
32221129	32221152	6	+	26627737	RPE1	viability after 18 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.12225859165074493	[1193]	[429,265]	0	hSpCas9	negative selection	1408472
32222644	32222667	6	+	26627737	RPE1	viability after 18 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.9213999872630885	[181]	[49,138]	5	hSpCas9	negative selection	1408473
32223009	32223032	6	+	26627737	RPE1	viability after 18 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-1.8998820091206243	[873]	[39,87]	-8	hSpCas9	negative selection	1408474
32219747	32219770	6	+	26627737	HeLa	viability after 8 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	-0.5846322966462328	[404]	[89,116,137]	-5	hSpCas9	negative selection	1490784
32220258	32220281	6	+	26627737	HeLa	viability after 8 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-0.009882865206200242	[357]	[176,106,182]	0	hSpCas9	negative selection	1490785
32220439	32220462	6	+	26627737	HeLa	viability after 8 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	-2.950891491717967	[23]	[0,1,0]	-9	hSpCas9	negative selection	1490786
32221129	32221152	6	+	26627737	HeLa	viability after 8 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	-0.3705002510174087	[820]	[362,340,152]	-4	hSpCas9	negative selection	1490787
32222644	32222667	6	+	26627737	HeLa	viability after 8 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	-0.18851894574428749	[415]	[234,109,148]	-2	hSpCas9	negative selection	1490788
32223009	32223032	6	+	26627737	HeLa	viability after 8 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.25440938585363876	[292]	[91,112,111]	-2	hSpCas9	negative selection	1490789
32219747	32219770	6	+	26627737	HeLa	viability after 12 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	0.1882226875431233	[404]	[122,323,108]	1	hSpCas9	negative selection	1573099
32220258	32220281	6	+	26627737	HeLa	viability after 12 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	0.17423305834361907	[357]	[260,124,121]	1	hSpCas9	negative selection	1573100
32220439	32220462	6	+	26627737	HeLa	viability after 12 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	0.36565344117469545	[23]	[26,0,11]	3	hSpCas9	negative selection	1573101
32221129	32221152	6	+	26627737	HeLa	viability after 12 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.02576472780531769	[820]	[282,301,453]	0	hSpCas9	negative selection	1573102
32222644	32222667	6	+	26627737	HeLa	viability after 12 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	-0.6973743555180358	[415]	[85,119,109]	-6	hSpCas9	negative selection	1573103
32223009	32223032	6	+	26627737	HeLa	viability after 12 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.0963373772169866	[292]	[96,87,156]	-1	hSpCas9	negative selection	1573104
32219747	32219770	6	+	26627737	HeLa	viability after 15 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	0.08319274205103487	[404]	[108,202,215]	0	hSpCas9	negative selection	1655414
32220258	32220281	6	+	26627737	HeLa	viability after 15 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-0.8955631960998952	[357]	[97,103,28]	-7	hSpCas9	negative selection	1655415
32220439	32220462	6	+	26627737	HeLa	viability after 15 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	0.8665382039543945	[23]	[29,20,0]	6	hSpCas9	negative selection	1655416
32221129	32221152	6	+	26627737	HeLa	viability after 15 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.0017287551564209025	[820]	[89,570,346]	0	hSpCas9	negative selection	1655417
32222644	32222667	6	+	26627737	HeLa	viability after 15 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.4101712253999733	[415]	[178,195,306]	3	hSpCas9	negative selection	1655418
32223009	32223032	6	+	26627737	HeLa	viability after 15 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.21950419293579324	[292]	[219,63,130]	1	hSpCas9	negative selection	1655419
32219747	32219770	6	+	26627737	HeLa	viability after 18 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	0.10842012596957346	[404]	[71,176,215]	0	hSpCas9	negative selection	1737729
32220258	32220281	6	+	26627737	HeLa	viability after 18 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-0.9227671987227838	[357]	[62,85,28]	-7	hSpCas9	negative selection	1737730
32220439	32220462	6	+	26627737	HeLa	viability after 18 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	0.9537821069761923	[23]	[20,18,0]	7	hSpCas9	negative selection	1737731
32221129	32221152	6	+	26627737	HeLa	viability after 18 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	-0.006783288450606495	[820]	[57,470,346]	0	hSpCas9	negative selection	1737732
32222644	32222667	6	+	26627737	HeLa	viability after 18 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.40773819097965264	[415]	[125,153,306]	3	hSpCas9	negative selection	1737733
32223009	32223032	6	+	26627737	HeLa	viability after 18 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.24487192370436608	[292]	[149,55,130]	2	hSpCas9	negative selection	1737734
32219747	32219770	6	+	26627737	HCT116	viability after 6 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	1.3296422194533064	[559]	[335,157]	7	hSpCas9	negative selection	1820044
32220258	32220281	6	+	26627737	HCT116	viability after 6 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	0.7163453932573082	[535]	[131,141]	4	hSpCas9	negative selection	1820045
32220439	32220462	6	+	26627737	HCT116	viability after 6 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	5.994603016487694	[0]	[0,14]	9	hSpCas9	negative selection	1820046
32221129	32221152	6	+	26627737	HCT116	viability after 6 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.4196389912425956	[926]	[493,29]	2	hSpCas9	negative selection	1820047
32222644	32222667	6	+	26627737	HCT116	viability after 6 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.5177781293903512	[190]	[100,10]	3	hSpCas9	negative selection	1820048
32223009	32223032	6	+	26627737	HCT116	viability after 6 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.08485297284498272	[393]	[46,75]	0	hSpCas9	negative selection	1820049
32219747	32219770	6	+	26627737	HCT116	viability after 8 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	1.8990912559103603	[105]	[248,177,226]	9	hSpCas9	negative selection	1902359
32220258	32220281	6	+	26627737	HCT116	viability after 8 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-0.9571297014534081	[351]	[121,68,108]	-8	hSpCas9	negative selection	1902360
32220439	32220462	6	+	26627737	HCT116	viability after 8 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	3.231674201998474	[1]	[8,8,12]	9	hSpCas9	negative selection	1902361
32221129	32221152	6	+	26627737	HCT116	viability after 8 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.60533251479925	[262]	[262,246,152]	6	hSpCas9	negative selection	1902362
32222644	32222667	6	+	26627737	HCT116	viability after 8 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	-0.37611458998094427	[315]	[181,140,80]	-4	hSpCas9	negative selection	1902363
32223009	32223032	6	+	26627737	HCT116	viability after 8 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.25907206930057836	[283]	[198,172,189]	3	hSpCas9	negative selection	1902364
32219747	32219770	6	+	26627737	HCT116	viability after 9 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	-1.02577073577579	[559]	[135,23]	-6	hSpCas9	negative selection	1984674
32220258	32220281	6	+	26627737	HCT116	viability after 9 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	1.527702223279365	[535]	[310,492]	8	hSpCas9	negative selection	1984675
32220439	32220462	6	+	26627737	HCT116	viability after 9 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	5.371493478666267	[0]	[0,18]	9	hSpCas9	negative selection	1984676
32221129	32221152	6	+	26627737	HCT116	viability after 9 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	-0.21118393902976662	[926]	[267,170]	-1	hSpCas9	negative selection	1984677
32222644	32222667	6	+	26627737	HCT116	viability after 9 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.6694954584217696	[190]	[79,81]	5	hSpCas9	negative selection	1984678
32223009	32223032	6	+	26627737	HCT116	viability after 9 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.7729124847128062	[393]	[57,275]	5	hSpCas9	negative selection	1984679
32219747	32219770	6	+	26627737	HCT116	viability after 12 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	1.7761947076285285	[105]	[251,147,165]	9	hSpCas9	negative selection	2066989
32220258	32220281	6	+	26627737	HCT116	viability after 12 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-0.42177148473239506	[351]	[145,113,152]	-4	hSpCas9	negative selection	2066990
32220439	32220462	6	+	26627737	HCT116	viability after 12 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	4.6801055633028295	[1]	[4,77,0]	9	hSpCas9	negative selection	2066991
32221129	32221152	6	+	26627737	HCT116	viability after 12 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.686166718908487	[262]	[221,296,149]	6	hSpCas9	negative selection	2066992
32222644	32222667	6	+	26627737	HCT116	viability after 12 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	-1.1321921442386207	[315]	[112,74,35]	-8	hSpCas9	negative selection	2066993
32223009	32223032	6	+	26627737	HCT116	viability after 12 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.023819272894939333	[283]	[115,182,144]	0	hSpCas9	negative selection	2066994
32219747	32219770	6	+	26627737	HCT116	viability after 15 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	1.5741080629282214	[105]	[316,120,122]	9	hSpCas9	negative selection	2149304
32220258	32220281	6	+	26627737	HCT116	viability after 15 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-1.6198761555440153	[351]	[119,24,58]	-9	hSpCas9	negative selection	2149305
32220439	32220462	6	+	26627737	HCT116	viability after 15 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	5.344536245878192	[1]	[27,84,24]	9	hSpCas9	negative selection	2149306
32221129	32221152	6	+	26627737	HCT116	viability after 15 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	1.012460897849966	[262]	[340,312,264]	8	hSpCas9	negative selection	2149307
32222644	32222667	6	+	26627737	HCT116	viability after 15 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	-0.364013312114857	[315]	[274,78,85]	-4	hSpCas9	negative selection	2149308
32223009	32223032	6	+	26627737	HCT116	viability after 15 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.4583182913346217	[283]	[78,128,142]	-5	hSpCas9	negative selection	2149309
32219747	32219770	6	+	26627737	HCT116	viability after 18 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	1.2111084584950014	[105]	[125,114,114]	8	hSpCas9	negative selection	2231619
32220258	32220281	6	+	26627737	HCT116	viability after 18 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-0.7419303668475066	[351]	[153,73,77]	-6	hSpCas9	negative selection	2231620
32220439	32220462	6	+	26627737	HCT116	viability after 18 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	5.187469157339803	[1]	[0,80,19]	9	hSpCas9	negative selection	2231621
32221129	32221152	6	+	26627737	HCT116	viability after 18 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.9249780914177421	[262]	[342,175,207]	7	hSpCas9	negative selection	2231622
32222644	32222667	6	+	26627737	HCT116	viability after 18 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	-0.047750400721667474	[315]	[128,175,135]	0	hSpCas9	negative selection	2231623
32223009	32223032	6	+	26627737	HCT116	viability after 18 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-1.0059730184824134	[283]	[23,95,83]	-7	hSpCas9	negative selection	2231624
32222741	32222764	6	+	24336569	HL60	viability	CAGAGCTGGGCGTTCTGGCAGGG	NOTCH4	ENSG00000204301	-0.46666348006048397	[972]	[1489]	-4	hSpCas9	negative selection	2280835
32222769	32222792	6	+	24336569	HL60	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.4990304262184789	[570]	[854]	-4	hSpCas9	negative selection	2280836
32222777	32222800	6	+	24336569	HL60	viability	CACGTCTCACCCAGGAAGCCAGG	NOTCH4	ENSG00000204301	0.7959742903516229	[352]	[1296]	6	hSpCas9	negative selection	2280837
32223009	32223032	6	+	24336569	HL60	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.11338929710926995	[407]	[933]	1	hSpCas9	negative selection	2280838
32223015	32223038	6	+	24336569	HL60	viability	CTTGTCCCAGAGACAGGCTCAGG	NOTCH4	ENSG00000204301	0.3187631878294702	[562]	[1485]	3	hSpCas9	negative selection	2280839
32223020	32223043	6	-	24336569	HL60	viability	ACCTGCCTGAGCCTGTCTCTGGG	NOTCH4	ENSG00000204301	0.22416218192936554	[1067]	[2639]	2	hSpCas9	negative selection	2280840
32223037	32223060	6	+	24336569	HL60	viability	GCAGGTGCCTCCATTGGCACAGG	NOTCH4	ENSG00000204301	1.0492395910156975	[173]	[761]	7	hSpCas9	negative selection	2280841
32223044	32223067	6	-	24336569	HL60	viability	CCAGAACCCTGTGCCAATGGAGG	NOTCH4	ENSG00000204301	-0.23701407979628475	[542]	[974]	-2	hSpCas9	negative selection	2280842
32223855	32223878	6	-	24336569	HL60	viability	GTCTCAGTGGTCAGACCCAGAGG	NOTCH4	ENSG00000204301	1.2767275382452377	[109]	[563]	8	hSpCas9	negative selection	2280843
32223868	32223891	6	-	24336569	HL60	viability	GCTGCTGCTATGTGTCTCAGTGG	NOTCH4	ENSG00000204301	0.4846745258006049	[179]	[532]	4	hSpCas9	negative selection	2280844
32222741	32222764	6	+	24336569	KBM7	viability	CAGAGCTGGGCGTTCTGGCAGGG	NOTCH4	ENSG00000204301	0.17377754143267293	[547]	[1685]	1	hSpCas9	negative selection	2348012
32222769	32222792	6	+	24336569	KBM7	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.030503786470833516	[618]	[1652]	0	hSpCas9	negative selection	2348013
32222777	32222800	6	+	24336569	KBM7	viability	CACGTCTCACCCAGGAAGCCAGG	NOTCH4	ENSG00000204301	0.17207602233843328	[314]	[967]	1	hSpCas9	negative selection	2348014
32223009	32223032	6	+	24336569	KBM7	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.9477595782051147	[317]	[1672]	7	hSpCas9	negative selection	2348015
32223015	32223038	6	+	24336569	KBM7	viability	CTTGTCCCAGAGACAGGCTCAGG	NOTCH4	ENSG00000204301	0.07026910831373667	[681]	[1952]	0	hSpCas9	negative selection	2348016
32223020	32223043	6	-	24336569	KBM7	viability	ACCTGCCTGAGCCTGTCTCTGGG	NOTCH4	ENSG00000204301	0.7959372113947385	[430]	[2040]	7	hSpCas9	negative selection	2348017
32223037	32223060	6	+	24336569	KBM7	viability	GCAGGTGCCTCCATTGGCACAGG	NOTCH4	ENSG00000204301	-0.6104911891608715	[294]	[526]	-5	hSpCas9	negative selection	2348018
32223044	32223067	6	-	24336569	KBM7	viability	CCAGAACCCTGTGCCAATGGAGG	NOTCH4	ENSG00000204301	-0.08500911716417436	[839]	[2159]	0	hSpCas9	negative selection	2348019
32223855	32223878	6	-	24336569	KBM7	viability	GTCTCAGTGGTCAGACCCAGAGG	NOTCH4	ENSG00000204301	-0.3551329477842875	[271]	[579]	-3	hSpCas9	negative selection	2348020
32223868	32223891	6	-	24336569	KBM7	viability	GCTGCTGCTATGTGTCTCAGTGG	NOTCH4	ENSG00000204301	0.5442622800639536	[265]	[1057]	5	hSpCas9	negative selection	2348021
32165573	32165596	CHR_HSCHR6_MHC_QBL_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCACTGCACTCCAGCCCAG	NOTCH4	ENSG00000206312	0.6031003623548207	[86,54]	[14,31]	2	dCas9-VP64	positive selection	2416203
32156437	32156460	CHR_HSCHR6_MHC_COX_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCACTGCACTCCAGCCCAG	NOTCH4	ENSG00000235396	0.6031003623548207	[86,54]	[14,31]	2	dCas9-VP64	positive selection	2416204
32215638	32215661	CHR_HSCHR6_MHC_SSTO_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCACTGCACTCCAGCCCAG	NOTCH4	ENSG00000234876	0.6031003623548207	[86,54]	[14,31]	2	dCas9-VP64	positive selection	2416205
32156944	32156967	CHR_HSCHR6_MHC_COX_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAATCCCAGCACTTTCAG	NOTCH4	ENSG00000235396	0.14000166748158183	[525,123]	[99,52]	0	dCas9-VP64	positive selection	2444579
32247861	32247884	CHR_HSCHR6_MHC_MANN_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAATCCCAGCACTTTCAG	NOTCH4	ENSG00000232339	0.14000166748158183	[525,123]	[99,52]	0	dCas9-VP64	positive selection	2444580
32284902	32284925	CHR_HSCHR6_MHC_MCF_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAATCCCAGCACTTTCAG	NOTCH4	ENSG00000223355	0.14000166748158183	[525,123]	[99,52]	0	dCas9-VP64	positive selection	2444581
32216147	32216170	CHR_HSCHR6_MHC_SSTO_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAATCCCAGCACTTTCAG	NOTCH4	ENSG00000234876	0.14000166748158183	[525,123]	[99,52]	0	dCas9-VP64	positive selection	2444582
32208471	32208494	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAATCCCAGCACTTTCAG	NOTCH4	ENSG00000204301	0.14000166748158183	[525,123]	[99,52]	0	dCas9-VP64	positive selection	2444583
32166084	32166107	CHR_HSCHR6_MHC_QBL_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAATCCCAGCACTTTCAG	NOTCH4	ENSG00000206312	0.14000166748158183	[525,123]	[99,52]	0	dCas9-VP64	positive selection	2444584
32235062	32235085	CHR_HSCHR6_MHC_MANN_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000232339	0.39640683935156806	[88,209]	[3,85]	1	dCas9-VP64	positive selection	2454308
32272100	32272123	CHR_HSCHR6_MHC_MCF_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000223355	0.39640683935156806	[88,209]	[3,85]	1	dCas9-VP64	positive selection	2454309
32144145	32144168	CHR_HSCHR6_MHC_COX_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000235396	0.39640683935156806	[88,209]	[3,85]	1	dCas9-VP64	positive selection	2454310
32153283	32153306	CHR_HSCHR6_MHC_QBL_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000206312	0.39640683935156806	[88,209]	[3,85]	1	dCas9-VP64	positive selection	2454311
32262683	32262706	CHR_HSCHR6_MHC_APD_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000238196	0.39640683935156806	[88,209]	[3,85]	1	dCas9-VP64	positive selection	2454312
32203347	32203370	CHR_HSCHR6_MHC_SSTO_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000234876	0.39640683935156806	[88,209]	[3,85]	1	dCas9-VP64	positive selection	2454313
32195677	32195700	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000204301	0.39640683935156806	[88,209]	[3,85]	1	dCas9-VP64	positive selection	2454314
32144070	32144093	CHR_HSCHR6_MHC_COX_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000235396	3.0253061245087833	[40,83]	[65,161]	8	dCas9-VP64	positive selection	2454315
32153208	32153231	CHR_HSCHR6_MHC_QBL_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000206312	3.0253061245087833	[40,83]	[65,161]	8	dCas9-VP64	positive selection	2454316
32262608	32262631	CHR_HSCHR6_MHC_APD_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000238196	3.0253061245087833	[40,83]	[65,161]	8	dCas9-VP64	positive selection	2454317
32203272	32203295	CHR_HSCHR6_MHC_SSTO_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000234876	3.0253061245087833	[40,83]	[65,161]	8	dCas9-VP64	positive selection	2454318
32195602	32195625	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000204301	3.0253061245087833	[40,83]	[65,161]	8	dCas9-VP64	positive selection	2454319
32234987	32235010	CHR_HSCHR6_MHC_MANN_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000232339	3.0253061245087833	[40,83]	[65,161]	8	dCas9-VP64	positive selection	2454320
32272025	32272048	CHR_HSCHR6_MHC_MCF_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000223355	3.0253061245087833	[40,83]	[65,161]	8	dCas9-VP64	positive selection	2454321
32203315	32203338	CHR_HSCHR6_MHC_SSTO_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000234876	-0.1813544333800503	[1238,137]	[191,66]	0	dCas9-VP64	positive selection	2454322
32195645	32195668	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000204301	-0.1813544333800503	[1238,137]	[191,66]	0	dCas9-VP64	positive selection	2454323
32235030	32235053	CHR_HSCHR6_MHC_MANN_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000232339	-0.1813544333800503	[1238,137]	[191,66]	0	dCas9-VP64	positive selection	2454324
32272068	32272091	CHR_HSCHR6_MHC_MCF_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000223355	-0.1813544333800503	[1238,137]	[191,66]	0	dCas9-VP64	positive selection	2454325
32144113	32144136	CHR_HSCHR6_MHC_COX_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000235396	-0.1813544333800503	[1238,137]	[191,66]	0	dCas9-VP64	positive selection	2454326
32153251	32153274	CHR_HSCHR6_MHC_QBL_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000206312	-0.1813544333800503	[1238,137]	[191,66]	0	dCas9-VP64	positive selection	2454327
32262651	32262674	CHR_HSCHR6_MHC_APD_CTG1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000238196	-0.1813544333800503	[1238,137]	[191,66]	0	dCas9-VP64	positive selection	2454328
32249187	32249210	CHR_HSCHR6_MHC_MANN_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTTGAACCTGGGAGGCGGGGG	NOTCH4	ENSG00000232339	-0.49448069816640183	[10,25]	[2,1]	-2	dCas9-VP64	positive selection	2460640
32286228	32286251	CHR_HSCHR6_MHC_MCF_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTTGAACCTGGGAGGCGGGGG	NOTCH4	ENSG00000223355	-0.49448069816640183	[10,25]	[2,1]	-2	dCas9-VP64	positive selection	2460641
32167410	32167433	CHR_HSCHR6_MHC_QBL_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTTGAACCTGGGAGGCGGGGG	NOTCH4	ENSG00000206312	-0.49448069816640183	[10,25]	[2,1]	-2	dCas9-VP64	positive selection	2460642
32158270	32158293	CHR_HSCHR6_MHC_COX_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTTGAACCTGGGAGGCGGGGG	NOTCH4	ENSG00000235396	-0.49448069816640183	[10,25]	[2,1]	-2	dCas9-VP64	positive selection	2460643
32209797	32209820	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTTGAACCTGGGAGGCGGGGG	NOTCH4	ENSG00000204301	-0.49448069816640183	[10,25]	[2,1]	-2	dCas9-VP64	positive selection	2460644
32217473	32217496	CHR_HSCHR6_MHC_SSTO_CTG1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTTGAACCTGGGAGGCGGGGG	NOTCH4	ENSG00000234876	-0.49448069816640183	[10,25]	[2,1]	-2	dCas9-VP64	positive selection	2460645
32165573	32165596	CHR_HSCHR6_MHC_QBL_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCACTGCACTCCAGCCCAG	NOTCH4	ENSG00000206312	-0.5652196159145948	[243,309]	[59,60]	-5	dCas9-VP64	positive selection	2511458
32156437	32156460	CHR_HSCHR6_MHC_COX_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCACTGCACTCCAGCCCAG	NOTCH4	ENSG00000235396	-0.5652196159145948	[243,309]	[59,60]	-5	dCas9-VP64	positive selection	2511459
32215638	32215661	CHR_HSCHR6_MHC_SSTO_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCACTGCACTCCAGCCCAG	NOTCH4	ENSG00000234876	-0.5652196159145948	[243,309]	[59,60]	-5	dCas9-VP64	positive selection	2511460
32156944	32156967	CHR_HSCHR6_MHC_COX_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAATCCCAGCACTTTCAG	NOTCH4	ENSG00000235396	2.3170246663226814	[189,235]	[324,366]	8	dCas9-VP64	positive selection	2539834
32247861	32247884	CHR_HSCHR6_MHC_MANN_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAATCCCAGCACTTTCAG	NOTCH4	ENSG00000232339	2.3170246663226814	[189,235]	[324,366]	8	dCas9-VP64	positive selection	2539835
32284902	32284925	CHR_HSCHR6_MHC_MCF_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAATCCCAGCACTTTCAG	NOTCH4	ENSG00000223355	2.3170246663226814	[189,235]	[324,366]	8	dCas9-VP64	positive selection	2539836
32216147	32216170	CHR_HSCHR6_MHC_SSTO_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAATCCCAGCACTTTCAG	NOTCH4	ENSG00000234876	2.3170246663226814	[189,235]	[324,366]	8	dCas9-VP64	positive selection	2539837
32208471	32208494	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAATCCCAGCACTTTCAG	NOTCH4	ENSG00000204301	2.3170246663226814	[189,235]	[324,366]	8	dCas9-VP64	positive selection	2539838
32166084	32166107	CHR_HSCHR6_MHC_QBL_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAATCCCAGCACTTTCAG	NOTCH4	ENSG00000206312	2.3170246663226814	[189,235]	[324,366]	8	dCas9-VP64	positive selection	2539839
32235062	32235085	CHR_HSCHR6_MHC_MANN_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000232339	0.6007814637490078	[83,54]	[30,36]	4	dCas9-VP64	positive selection	2549563
32272100	32272123	CHR_HSCHR6_MHC_MCF_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000223355	0.6007814637490078	[83,54]	[30,36]	4	dCas9-VP64	positive selection	2549564
32144145	32144168	CHR_HSCHR6_MHC_COX_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000235396	0.6007814637490078	[83,54]	[30,36]	4	dCas9-VP64	positive selection	2549565
32153283	32153306	CHR_HSCHR6_MHC_QBL_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000206312	0.6007814637490078	[83,54]	[30,36]	4	dCas9-VP64	positive selection	2549566
32262683	32262706	CHR_HSCHR6_MHC_APD_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000238196	0.6007814637490078	[83,54]	[30,36]	4	dCas9-VP64	positive selection	2549567
32203347	32203370	CHR_HSCHR6_MHC_SSTO_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000234876	0.6007814637490078	[83,54]	[30,36]	4	dCas9-VP64	positive selection	2549568
32195677	32195700	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCAGGCATGCGCGGGCCTCGG	NOTCH4	ENSG00000204301	0.6007814637490078	[83,54]	[30,36]	4	dCas9-VP64	positive selection	2549569
32144070	32144093	CHR_HSCHR6_MHC_COX_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000235396	1.0460572540777555	[38,102]	[30,62]	6	dCas9-VP64	positive selection	2549570
32153208	32153231	CHR_HSCHR6_MHC_QBL_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000206312	1.0460572540777555	[38,102]	[30,62]	6	dCas9-VP64	positive selection	2549571
32262608	32262631	CHR_HSCHR6_MHC_APD_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000238196	1.0460572540777555	[38,102]	[30,62]	6	dCas9-VP64	positive selection	2549572
32203272	32203295	CHR_HSCHR6_MHC_SSTO_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000234876	1.0460572540777555	[38,102]	[30,62]	6	dCas9-VP64	positive selection	2549573
32195602	32195625	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000204301	1.0460572540777555	[38,102]	[30,62]	6	dCas9-VP64	positive selection	2549574
32234987	32235010	CHR_HSCHR6_MHC_MANN_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000232339	1.0460572540777555	[38,102]	[30,62]	6	dCas9-VP64	positive selection	2549575
32272025	32272048	CHR_HSCHR6_MHC_MCF_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGGTCTCAACGGATGACTGG	NOTCH4	ENSG00000223355	1.0460572540777555	[38,102]	[30,62]	6	dCas9-VP64	positive selection	2549576
32203315	32203338	CHR_HSCHR6_MHC_SSTO_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000234876	2.8340204878279653	[161,121]	[623,58]	9	dCas9-VP64	positive selection	2549577
32195645	32195668	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000204301	2.8340204878279653	[161,121]	[623,58]	9	dCas9-VP64	positive selection	2549578
32235030	32235053	CHR_HSCHR6_MHC_MANN_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000232339	2.8340204878279653	[161,121]	[623,58]	9	dCas9-VP64	positive selection	2549579
32272068	32272091	CHR_HSCHR6_MHC_MCF_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000223355	2.8340204878279653	[161,121]	[623,58]	9	dCas9-VP64	positive selection	2549580
32144113	32144136	CHR_HSCHR6_MHC_COX_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000235396	2.8340204878279653	[161,121]	[623,58]	9	dCas9-VP64	positive selection	2549581
32153251	32153274	CHR_HSCHR6_MHC_QBL_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000206312	2.8340204878279653	[161,121]	[623,58]	9	dCas9-VP64	positive selection	2549582
32262651	32262674	CHR_HSCHR6_MHC_APD_CTG1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGATAATGCGAGGAAGATACGG	NOTCH4	ENSG00000238196	2.8340204878279653	[161,121]	[623,58]	9	dCas9-VP64	positive selection	2549583
32249187	32249210	CHR_HSCHR6_MHC_MANN_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTTGAACCTGGGAGGCGGGGG	NOTCH4	ENSG00000232339	-1.2686416065166946	[152,79]	[23,7]	-9	dCas9-VP64	positive selection	2555895
32286228	32286251	CHR_HSCHR6_MHC_MCF_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTTGAACCTGGGAGGCGGGGG	NOTCH4	ENSG00000223355	-1.2686416065166946	[152,79]	[23,7]	-9	dCas9-VP64	positive selection	2555896
32167410	32167433	CHR_HSCHR6_MHC_QBL_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTTGAACCTGGGAGGCGGGGG	NOTCH4	ENSG00000206312	-1.2686416065166946	[152,79]	[23,7]	-9	dCas9-VP64	positive selection	2555897
32158270	32158293	CHR_HSCHR6_MHC_COX_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTTGAACCTGGGAGGCGGGGG	NOTCH4	ENSG00000235396	-1.2686416065166946	[152,79]	[23,7]	-9	dCas9-VP64	positive selection	2555898
32209797	32209820	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTTGAACCTGGGAGGCGGGGG	NOTCH4	ENSG00000204301	-1.2686416065166946	[152,79]	[23,7]	-9	dCas9-VP64	positive selection	2555899
32217473	32217496	CHR_HSCHR6_MHC_SSTO_CTG1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTTGAACCTGGGAGGCGGGGG	NOTCH4	ENSG00000234876	-1.2686416065166946	[152,79]	[23,7]	-9	dCas9-VP64	positive selection	2555900
32218040	32218063	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCTCCCTGCCTGAACCACGCGG	NOTCH4	ENSG00000204301	0.46659480276890075	[2,3]	[1,5]	8	hSpCas9	positive selection	3006108
32218018	32218041	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATTGCCATGACCTGCTCAACGG	NOTCH4	ENSG00000204301	0.006814176465820304	[3,3]	[2,2]	0	hSpCas9	positive selection	3006109
32218026	32218049	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	0.5287648303558131	[3,2]	[4,2]	9	hSpCas9	positive selection	3006110
32213231	32213254	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTACCCCCATTGAAGCACGGGG	NOTCH4	ENSG00000204301	-0.4683228691554162	[3,3]	[2,0]	-6	hSpCas9	positive selection	3006111
32218040	32218063	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCTCCCTGCCTGAACCACGCGG	NOTCH4	ENSG00000204301	-0.36385610612492353	[2,2]	[2,0]	-5	hSpCas9	positive selection	3073966
32218018	32218041	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATTGCCATGACCTGCTCAACGG	NOTCH4	ENSG00000204301	0.28350464032538925	[3,3]	[3,2]	5	hSpCas9	positive selection	3073967
32218026	32218049	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	-0.5102964128261087	[3,3]	[2,0]	-7	hSpCas9	positive selection	3073968
32213231	32213254	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTACCCCCATTGAAGCACGGGG	NOTCH4	ENSG00000204301	-0.16987376195925	[3,3]	[2,1]	-2	hSpCas9	positive selection	3073969
32222732	32222755		-	24336571	A375	resistance to PLX after 7 days	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.4749584573945915	[4,5]	[3,3]	-9	hSpCas9	positive selection	3131213
32223009	32223032		+	24336571	A375	resistance to PLX after 7 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.21069316681467715	[11,13]	[9,11]	-6	hSpCas9	positive selection	3131214
32222769	32222792		+	24336571	A375	resistance to PLX after 7 days	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.06796697091604564	[12,10]	[13,11]	2	hSpCas9	positive selection	3131215
32223047	32223070		-	24336571	A375	resistance to PLX after 7 days	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.09309449717596477	[11,9]	[11,8]	-3	hSpCas9	positive selection	3131216
32222732	32222755		-	24336571	A375	resistance to PLX after 14 days	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.2873607520818393	[2,7]	[1,1]	-3	hSpCas9	positive selection	3189006
32223009	32223032		+	24336571	A375	resistance to PLX after 14 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.010398994740811018	[6,10]	[2,3]	0	hSpCas9	positive selection	3189007
32222769	32222792		+	24336571	A375	resistance to PLX after 14 days	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.3847763174944351	[11,12]	[4,2]	-4	hSpCas9	positive selection	3189008
32223047	32223070		-	24336571	A375	resistance to PLX after 14 days	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.31254453670049415	[9,8]	[3,2]	-4	hSpCas9	positive selection	3189009
32222732	32222755		-	24336571	A375	viability after 7 days	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.3325002152829526	[4]	[4,5]	5	hSpCas9	negative selection	3246799
32223009	32223032		+	24336571	A375	viability after 7 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.31603517741340265	[10]	[11,13]	5	hSpCas9	negative selection	3246800
32222769	32222792		+	24336571	A375	viability after 7 days	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.46607060902819025	[17]	[12,10]	-6	hSpCas9	negative selection	3246801
32223047	32223070		-	24336571	A375	viability after 7 days	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	0.2163520018255268	[9]	[11,9]	3	hSpCas9	negative selection	3246802
32222732	32222755		-	24336571	A375	viability after 14 days	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.3465069351840748	[4]	[2,7]	4	hSpCas9	negative selection	3304592
32223009	32223032		+	24336571	A375	viability after 14 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.16923054421389955	[10]	[6,10]	-2	hSpCas9	negative selection	3304593
32222769	32222792		+	24336571	A375	viability after 14 days	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.42776806110123977	[17]	[11,12]	-5	hSpCas9	negative selection	3304594
32223047	32223070		-	24336571	A375	viability after 14 days	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	0.03334362538138741	[9]	[9,8]	0	hSpCas9	negative selection	3304595
32220845	32220868	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	-0.4291743157373832	[205,205]	[0,0]	-3	hSpCas9	positive selection	3382091
32223047	32223070	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	0.18051061439500407	[134,134]	[0,0]	1	hSpCas9	positive selection	3382092
32223009	32223032	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.9905396707509337	[76,76]	[0,0]	4	hSpCas9	positive selection	3382093
32218040	32218063	6	-	26780180	HT29	viability (Avana library 4 designs)	AGCTCCCTGCCTGAACCACGCGG	NOTCH4	ENSG00000204301	0.211171334573471	[]	[]	0	hSpCas9	negative selection	3443966
32218018	32218041	6	-	26780180	HT29	viability (Avana library 4 designs)	GATTGCCATGACCTGCTCAACGG	NOTCH4	ENSG00000204301	0.28730625748258	[]	[]	1	hSpCas9	negative selection	3443967
32218025	32218048	6	+	26780180	HT29	viability (Avana library 4 designs)	GCAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	1.58515940099927	[]	[]	6	hSpCas9	negative selection	3443968
32213230	32213253	6	+	26780180	HT29	viability (Avana library 4 designs)	GGTACCCCCATTGAAGCACGGGG	NOTCH4	ENSG00000204301	0.484754708710007	[]	[]	1	hSpCas9	negative selection	3443969
32218025	32218048	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	3.08758061454233	[]	[]	5	hSpCas9	negative selection	3535919
32213230	32213253	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTACCCCCATTGAAGCACGGGG	NOTCH4	ENSG00000204301	1.39984674911197	[]	[]	2	hSpCas9	negative selection	3535920
32218040	32218063	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGCTCCCTGCCTGAACCACGCGG	NOTCH4	ENSG00000204301	2.11164963048486	[]	[]	3	hSpCas9	negative selection	3535921
32218018	32218041	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATTGCCATGACCTGCTCAACGG	NOTCH4	ENSG00000204301	3.66656398083041	[]	[]	6	hSpCas9	negative selection	3535922
32221052	32221075	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGACCCTGCCCTCCTAGGGG	NOTCH4	ENSG00000204301	2.17593342495271	[]	[]	3	hSpCas9	negative selection	3535923
32221266	32221289	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACACCCCTCCATTAACACATGGG	NOTCH4	ENSG00000204301	-5.05232810757411	[]	[]	-5	hSpCas9	negative selection	3535924
32218025	32218048	6	+	26780180	A375	viability (Avana lentiGuide)	GCAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	4.68357658283753	[]	[]	4	hSpCas9	negative selection	3644578
32213230	32213253	6	+	26780180	A375	viability (Avana lentiGuide)	GGTACCCCCATTGAAGCACGGGG	NOTCH4	ENSG00000204301	-1.83792511309547	[]	[]	-3	hSpCas9	negative selection	3644579
32218040	32218063	6	-	26780180	A375	viability (Avana lentiGuide)	AGCTCCCTGCCTGAACCACGCGG	NOTCH4	ENSG00000204301	-1.70366005225246	[]	[]	-3	hSpCas9	negative selection	3644580
32218018	32218041	6	-	26780180	A375	viability (Avana lentiGuide)	GATTGCCATGACCTGCTCAACGG	NOTCH4	ENSG00000204301	-0.123748671938965	[]	[]	0	hSpCas9	negative selection	3644581
32221052	32221075	6	-	26780180	A375	viability (Avana lentiGuide)	GCAGGACCCTGCCCTCCTAGGGG	NOTCH4	ENSG00000204301	7.0287751169871	[]	[]	5	hSpCas9	negative selection	3644582
32221266	32221289	6	+	26780180	A375	viability (Avana lentiGuide)	ACACCCCTCCATTAACACATGGG	NOTCH4	ENSG00000204301	-3.80553168208782	[]	[]	-6	hSpCas9	negative selection	3644583
32218025	32218048	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	0.1732812188406948	[3]	[4,3]	5	hSpCas9	positive selection	3753237
32213230	32213253	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTACCCCCATTGAAGCACGGGG	NOTCH4	ENSG00000204301	0.23849395018890046	[4]	[4,5]	6	hSpCas9	positive selection	3753238
32218040	32218063	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCTCCCTGCCTGAACCACGCGG	NOTCH4	ENSG00000204301	0.03870954010792868	[4]	[4,4]	1	hSpCas9	positive selection	3753239
32218018	32218041	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATTGCCATGACCTGCTCAACGG	NOTCH4	ENSG00000204301	0.3309755553325189	[4]	[5,5]	8	hSpCas9	positive selection	3753240
32221052	32221075	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGACCCTGCCCTCCTAGGGG	NOTCH4	ENSG00000204301	0.20332270296084476	[4]	[4,4]	5	hSpCas9	positive selection	3753241
32221266	32221289	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACACCCCTCCATTAACACATGGG	NOTCH4	ENSG00000204301	-0.46600766134827265	[5]	[3,3]	-6	hSpCas9	positive selection	3753242
32218025	32218048	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	-0.06715313756028615	[4]	[2,4]	-1	hSpCas9	positive selection	3861844
32213230	32213253	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTACCCCCATTGAAGCACGGGG	NOTCH4	ENSG00000204301	-0.267685374335497	[4]	[3,2]	-4	hSpCas9	positive selection	3861845
32218040	32218063	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCTCCCTGCCTGAACCACGCGG	NOTCH4	ENSG00000204301	-0.6365185421901574	[5]	[1,3]	-7	hSpCas9	positive selection	3861846
32218018	32218041	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATTGCCATGACCTGCTCAACGG	NOTCH4	ENSG00000204301	0.2894160988195982	[5]	[5,5]	7	hSpCas9	positive selection	3861847
32221052	32221075	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGACCCTGCCCTCCTAGGGG	NOTCH4	ENSG00000204301	0.08397716157598643	[4]	[4,3]	1	hSpCas9	positive selection	3861848
32221266	32221289	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACACCCCTCCATTAACACATGGG	NOTCH4	ENSG00000204301	0.292451848969008	[6]	[6,7]	7	hSpCas9	positive selection	3861849
32222732	32222755	6	-	26780180	A375	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	1.05142407133015	[]	[]	5	hSpCas9	negative selection	3973162
32223009	32223032	6	+	26780180	A375	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	1.44961758896351	[]	[]	8	hSpCas9	negative selection	3973163
32222769	32222792	6	+	26780180	A375	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.358823239145383	[]	[]	0	hSpCas9	negative selection	3973164
32220815	32220838	6	-	26780180	A375	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.255652484236124	[]	[]	0	hSpCas9	negative selection	3973165
32220845	32220868	6	+	26780180	A375	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.595870761722722	[]	[]	1	hSpCas9	negative selection	3973166
32223047	32223070	6	-	26780180	A375	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	1.31743580182796	[]	[]	7	hSpCas9	negative selection	3973167
32222732	32222755	6	-	26780180	HT29	viability (GeCKOv2 library)	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.95857265267107	[]	[]	4	hSpCas9	negative selection	4081128
32223009	32223032	6	+	26780180	HT29	viability (GeCKOv2 library)	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	1.59200494746985	[]	[]	8	hSpCas9	negative selection	4081129
32222769	32222792	6	+	26780180	HT29	viability (GeCKOv2 library)	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.783550394188497	[]	[]	3	hSpCas9	negative selection	4081130
32220815	32220838	6	-	26780180	HT29	viability (GeCKOv2 library)	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.765710670766957	[]	[]	3	hSpCas9	negative selection	4081131
32220845	32220868	6	+	26780180	HT29	viability (GeCKOv2 library)	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.565631886718602	[]	[]	2	hSpCas9	negative selection	4081132
32223047	32223070	6	-	26780180	HT29	viability (GeCKOv2 library)	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	1.85584724857079	[]	[]	8	hSpCas9	negative selection	4081133
32222732	32222755	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.3935180374451369	[1]	[0,0]	-7	hSpCas9	positive selection	4155903
32223009	32223032	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.07186952983394085	[3]	[2,1]	1	hSpCas9	positive selection	4155904
32222769	32222792	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.23558496135444662	[3]	[1,1]	-5	hSpCas9	positive selection	4155905
32223047	32223070	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.2551018892039501	[3]	[2,1]	-6	hSpCas9	positive selection	4155906
32222732	32222755	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.7634189934965199	[2]	[0,0,0,0]	-9	hSpCas9	positive selection	4219925
32223009	32223032	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.609418961193064	[3]	[4,4,3,0]	4	hSpCas9	positive selection	4219926
32222769	32222792	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.5692696125891114	[3]	[0,0,2,0]	-7	hSpCas9	positive selection	4219927
32223047	32223070	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	1.1487878410286263	[2]	[4,2,4,0]	8	hSpCas9	positive selection	4219928
32222769	32222792	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.6280424487522436	[3]	[3,4]	9	hSpCas9	positive selection	4286007
32220815	32220838	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	-0.1555884255750563	[2]	[2,1]	-3	hSpCas9	positive selection	4286008
32222732	32222755	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.26911039082401095	[2]	[2,1]	5	hSpCas9	positive selection	4286009
32220845	32220868	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.7022640961473618	[3]	[3,4]	9	hSpCas9	positive selection	4350264
32223047	32223070	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.22854829879581096	[2]	[2,1]	-5	hSpCas9	positive selection	4350265
32223009	32223032	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.09037456081834988	[2]	[2,0]	-2	hSpCas9	positive selection	4350266
32212890	32212912	6	+	27760321	OCIAML3	viability	GGTTGCCCTATTCCTACAGGGG	NOTCH4	ENSG00000204301	0.5340825403933748	[406,346]	[392,467]	6	hSpCas9	negative selection	4423013
32217232	32217254	6	+	27760321	OCIAML3	viability	ATCGATATCCTCCTCACATCGG	NOTCH4	ENSG00000204301	0.7296083108268927	[260,227]	[298,338]	8	hSpCas9	negative selection	4423014
32218026	32218048	6	+	27760321	OCIAML3	viability	CAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	0.039423708607040364	[814,660]	[530,666]	0	hSpCas9	negative selection	4423015
32221039	32221061	6	-	27760321	OCIAML3	viability	TCCTAGGGGCTGTTCGAATGGG	NOTCH4	ENSG00000204301	0.14378687278054678	[391,289]	[258,334]	1	hSpCas9	negative selection	4423016
32221210	32221232	6	+	27760321	OCIAML3	viability	ATGGCCCTCGAAGCCCGGTGGG	NOTCH4	ENSG00000204301	-0.45050648974716206	[555,540]	[278,360]	-4	hSpCas9	negative selection	4423017
32212890	32212912	6	+	27760321	OCIAML2	viability	GGTTGCCCTATTCCTACAGGGG	NOTCH4	ENSG00000204301	-0.3646207406396733	[406,346]	[179,309]	-4	hSpCas9	negative selection	4506476
32217232	32217254	6	+	27760321	OCIAML2	viability	ATCGATATCCTCCTCACATCGG	NOTCH4	ENSG00000204301	-0.29500050616788287	[260,227]	[140,186]	-4	hSpCas9	negative selection	4506477
32218026	32218048	6	+	27760321	OCIAML2	viability	CAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	0.43976061289642765	[814,660]	[669,983]	6	hSpCas9	negative selection	4506478
32221039	32221061	6	-	27760321	OCIAML2	viability	TCCTAGGGGCTGTTCGAATGGG	NOTCH4	ENSG00000204301	0.0020019086454768353	[391,289]	[246,308]	0	hSpCas9	negative selection	4506479
32221210	32221232	6	+	27760321	OCIAML2	viability	ATGGCCCTCGAAGCCCGGTGGG	NOTCH4	ENSG00000204301	0.04841316324131828	[555,540]	[439,485]	0	hSpCas9	negative selection	4506480
32212890	32212912	6	+	27760321	MV411	viability	GGTTGCCCTATTCCTACAGGGG	NOTCH4	ENSG00000204301	-0.9038117833842794	[406,346]	[54,248]	-6	hSpCas9	negative selection	4589939
32217232	32217254	6	+	27760321	MV411	viability	ATCGATATCCTCCTCACATCGG	NOTCH4	ENSG00000204301	0.9854277939383385	[260,227]	[472,86]	7	hSpCas9	negative selection	4589940
32218026	32218048	6	+	27760321	MV411	viability	CAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	-0.037603072318297626	[814,660]	[437,522]	0	hSpCas9	negative selection	4589941
32221039	32221061	6	-	27760321	MV411	viability	TCCTAGGGGCTGTTCGAATGGG	NOTCH4	ENSG00000204301	0.6385507482047125	[391,289]	[60,776]	5	hSpCas9	negative selection	4589942
32221210	32221232	6	+	27760321	MV411	viability	ATGGCCCTCGAAGCCCGGTGGG	NOTCH4	ENSG00000204301	-0.8128501389770968	[555,540]	[74,403]	-5	hSpCas9	negative selection	4589943
32212890	32212912	6	+	27760321	HL60	viability	GGTTGCCCTATTCCTACAGGGG	NOTCH4	ENSG00000204301	0.5911363619753396	[406,346]	[293,640]	7	hSpCas9	negative selection	4673402
32217232	32217254	6	+	27760321	HL60	viability	ATCGATATCCTCCTCACATCGG	NOTCH4	ENSG00000204301	-0.6110654056151661	[260,227]	[145,113]	-6	hSpCas9	negative selection	4673403
32218026	32218048	6	+	27760321	HL60	viability	CAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	0.2803614121135408	[814,660]	[787,664]	3	hSpCas9	negative selection	4673404
32221039	32221061	6	-	27760321	HL60	viability	TCCTAGGGGCTGTTCGAATGGG	NOTCH4	ENSG00000204301	0.10559328521704853	[391,289]	[313,278]	1	hSpCas9	negative selection	4673405
32221210	32221232	6	+	27760321	HL60	viability	ATGGCCCTCGAAGCCCGGTGGG	NOTCH4	ENSG00000204301	-0.3514458803601282	[555,540]	[316,388]	-4	hSpCas9	negative selection	4673406
32212890	32212912	6	+	27760321	HT1080	viability	GGTTGCCCTATTCCTACAGGGG	NOTCH4	ENSG00000204301	-0.1014094419393507	[346,270]	[140,85]	0	hSpCas9	negative selection	4756865
32217232	32217254	6	+	27760321	HT1080	viability	ATCGATATCCTCCTCACATCGG	NOTCH4	ENSG00000204301	0.13700072710628497	[227,177]	[118,55]	0	hSpCas9	negative selection	4756866
32218026	32218048	6	+	27760321	HT1080	viability	CAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	0.45425191029876455	[660,515]	[314,327]	2	hSpCas9	negative selection	4756867
32221039	32221061	6	-	27760321	HT1080	viability	TCCTAGGGGCTGTTCGAATGGG	NOTCH4	ENSG00000204301	1.3087352026752193	[289,226]	[173,343]	7	hSpCas9	negative selection	4756868
32221210	32221232	6	+	27760321	HT1080	viability	ATGGCCCTCGAAGCCCGGTGGG	NOTCH4	ENSG00000204301	0.02282428160213884	[540,421]	[307,70]	0	hSpCas9	negative selection	4756869
32212890	32212912	6	+	27760321	HT29	viability after 7 days	GGTTGCCCTATTCCTACAGGGG	NOTCH4	ENSG00000204301	-0.18826791226065798	[346,270]	[328,276,433]	-3	hSpCas9	negative selection	4840328
32217232	32217254	6	+	27760321	HT29	viability after 7 days	ATCGATATCCTCCTCACATCGG	NOTCH4	ENSG00000204301	0.5801211075451346	[227,177]	[570,240,383]	8	hSpCas9	negative selection	4840329
32218026	32218048	6	+	27760321	HT29	viability after 7 days	CAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	0.443424363203482	[660,515]	[1011,1173,900]	6	hSpCas9	negative selection	4840330
32221039	32221061	6	-	27760321	HT29	viability after 7 days	TCCTAGGGGCTGTTCGAATGGG	NOTCH4	ENSG00000204301	0.06631568648377884	[289,226]	[426,377,252]	1	hSpCas9	negative selection	4840331
32221210	32221232	6	+	27760321	HT29	viability after 7 days	ATGGCCCTCGAAGCCCGGTGGG	NOTCH4	ENSG00000204301	0.023151125300900355	[540,421]	[719,605,574]	0	hSpCas9	negative selection	4840332
32212890	32212912	6	+	27760321	HT29	viability after 25 days	GGTTGCCCTATTCCTACAGGGG	NOTCH4	ENSG00000204301	0.49560038766632875	[346,270]	[319,635,553]	5	hSpCas9	negative selection	4923791
32217232	32217254	6	+	27760321	HT29	viability after 25 days	ATCGATATCCTCCTCACATCGG	NOTCH4	ENSG00000204301	0.5672223701214509	[227,177]	[330,162,559]	6	hSpCas9	negative selection	4923792
32218026	32218048	6	+	27760321	HT29	viability after 25 days	CAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	0.7169425689764208	[660,515]	[892,1063,1401]	7	hSpCas9	negative selection	4923793
32221039	32221061	6	-	27760321	HT29	viability after 25 days	TCCTAGGGGCTGTTCGAATGGG	NOTCH4	ENSG00000204301	0.44062301712796875	[289,226]	[310,496,399]	5	hSpCas9	negative selection	4923794
32221210	32221232	6	+	27760321	HT29	viability after 25 days	ATGGCCCTCGAAGCCCGGTGGG	NOTCH4	ENSG00000204301	0.5040130275018644	[540,421]	[661,760,940]	5	hSpCas9	negative selection	4923795
32212890	32212912	6	+	27760321	HT29	viability after 22 days	GGTTGCCCTATTCCTACAGGGG	NOTCH4	ENSG00000204301	0.21201088990917843	[346,270]	[311,422,509]	2	hSpCas9	negative selection	5007254
32217232	32217254	6	+	27760321	HT29	viability after 22 days	ATCGATATCCTCCTCACATCGG	NOTCH4	ENSG00000204301	0.731979734062893	[227,177]	[474,306,384]	8	hSpCas9	negative selection	5007255
32218026	32218048	6	+	27760321	HT29	viability after 22 days	CAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	0.718056713644581	[660,515]	[838,1192,1334]	7	hSpCas9	negative selection	5007256
32221039	32221061	6	-	27760321	HT29	viability after 22 days	TCCTAGGGGCTGTTCGAATGGG	NOTCH4	ENSG00000204301	0.39828915101450496	[289,226]	[435,310,433]	4	hSpCas9	negative selection	5007257
32221210	32221232	6	+	27760321	HT29	viability after 22 days	ATGGCCCTCGAAGCCCGGTGGG	NOTCH4	ENSG00000204301	0.3568045715440239	[540,421]	[696,811,628]	4	hSpCas9	negative selection	5007258
32212890	32212912	6	+	27760321	HT29	viability after 19 days	GGTTGCCCTATTCCTACAGGGG	NOTCH4	ENSG00000204301	0.7116133780456007	[346,270]	[514,495,712]	7	hSpCas9	negative selection	5090717
32217232	32217254	6	+	27760321	HT29	viability after 19 days	ATCGATATCCTCCTCACATCGG	NOTCH4	ENSG00000204301	0.5161088471407229	[227,177]	[324,200,463]	5	hSpCas9	negative selection	5090718
32218026	32218048	6	+	27760321	HT29	viability after 19 days	CAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	0.9063689909233816	[660,515]	[1218,1263,1294]	8	hSpCas9	negative selection	5090719
32221039	32221061	6	-	27760321	HT29	viability after 19 days	TCCTAGGGGCTGTTCGAATGGG	NOTCH4	ENSG00000204301	0.3197420409912958	[289,226]	[518,351,255]	3	hSpCas9	negative selection	5090720
32221210	32221232	6	+	27760321	HT29	viability after 19 days	ATGGCCCTCGAAGCCCGGTGGG	NOTCH4	ENSG00000204301	0.4944808622320842	[540,421]	[816,1002,520]	5	hSpCas9	negative selection	5090721
32212890	32212912	6	+	27760321	HT29	viability after 16 days	GGTTGCCCTATTCCTACAGGGG	NOTCH4	ENSG00000204301	-0.42696299891310036	[346,270]	[180,342,237]	-4	hSpCas9	negative selection	5174180
32217232	32217254	6	+	27760321	HT29	viability after 16 days	ATCGATATCCTCCTCACATCGG	NOTCH4	ENSG00000204301	0.2547883150688909	[227,177]	[385,224,213]	2	hSpCas9	negative selection	5174181
32218026	32218048	6	+	27760321	HT29	viability after 16 days	CAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	0.5753259273221043	[660,515]	[849,1005,1073]	6	hSpCas9	negative selection	5174182
32221039	32221061	6	-	27760321	HT29	viability after 16 days	TCCTAGGGGCTGTTCGAATGGG	NOTCH4	ENSG00000204301	0.8342118009304172	[289,226]	[458,466,616]	8	hSpCas9	negative selection	5174183
32221210	32221232	6	+	27760321	HT29	viability after 16 days	ATGGCCCTCGAAGCCCGGTGGG	NOTCH4	ENSG00000204301	0.2511043837407463	[540,421]	[585,793,533]	2	hSpCas9	negative selection	5174184
32212890	32212912	6	+	27760321	HT29	viability after 13 days	GGTTGCCCTATTCCTACAGGGG	NOTCH4	ENSG00000204301	0.19390604328283276	[346,270]	[319,494,414]	2	hSpCas9	negative selection	5257643
32217232	32217254	6	+	27760321	HT29	viability after 13 days	ATCGATATCCTCCTCACATCGG	NOTCH4	ENSG00000204301	0.7867732976439864	[227,177]	[854,147,225]	9	hSpCas9	negative selection	5257644
32218026	32218048	6	+	27760321	HT29	viability after 13 days	CAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	0.8270439372631073	[660,515]	[1256,1279,1102]	9	hSpCas9	negative selection	5257645
32221039	32221061	6	-	27760321	HT29	viability after 13 days	TCCTAGGGGCTGTTCGAATGGG	NOTCH4	ENSG00000204301	0.5779431715085885	[289,226]	[396,613,338]	7	hSpCas9	negative selection	5257646
32221210	32221232	6	+	27760321	HT29	viability after 13 days	ATGGCCCTCGAAGCCCGGTGGG	NOTCH4	ENSG00000204301	0.04765562643564497	[540,421]	[508,661,561]	0	hSpCas9	negative selection	5257647
32212890	32212912	6	+	27760321	HT29	viability after 10 days	GGTTGCCCTATTCCTACAGGGG	NOTCH4	ENSG00000204301	0.05779609300092836	[346,270]	[362,504,340]	0	hSpCas9	negative selection	5341106
32217232	32217254	6	+	27760321	HT29	viability after 10 days	ATCGATATCCTCCTCACATCGG	NOTCH4	ENSG00000204301	0.4000858076867259	[227,177]	[384,264,350]	5	hSpCas9	negative selection	5341107
32218026	32218048	6	+	27760321	HT29	viability after 10 days	CAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	0.6714748425233792	[660,515]	[1077,1237,1195]	8	hSpCas9	negative selection	5341108
32221039	32221061	6	-	27760321	HT29	viability after 10 days	TCCTAGGGGCTGTTCGAATGGG	NOTCH4	ENSG00000204301	0.17862347766165432	[289,226]	[385,415,296]	2	hSpCas9	negative selection	5341109
32221210	32221232	6	+	27760321	HT29	viability after 10 days	ATGGCCCTCGAAGCCCGGTGGG	NOTCH4	ENSG00000204301	0.043854702931001854	[540,421]	[564,442,840]	0	hSpCas9	negative selection	5341110
32212890	32212912	6	+	27760321	MOLM13	viability	GGTTGCCCTATTCCTACAGGGG	NOTCH4	ENSG00000204301	-0.04694383451865644	[406,346]	[329,98]	0	hSpCas9	negative selection	5424569
32217232	32217254	6	+	27760321	MOLM13	viability	ATCGATATCCTCCTCACATCGG	NOTCH4	ENSG00000204301	0.35089384068432977	[260,227]	[201,152]	2	hSpCas9	negative selection	5424570
32218026	32218048	6	+	27760321	MOLM13	viability	CAGGTCATGGCAATCCGCGTGG	NOTCH4	ENSG00000204301	-0.567730375446047	[814,660]	[360,209]	-4	hSpCas9	negative selection	5424571
32221039	32221061	6	-	27760321	MOLM13	viability	TCCTAGGGGCTGTTCGAATGGG	NOTCH4	ENSG00000204301	0.5092548203428793	[391,289]	[373,183]	3	hSpCas9	negative selection	5424572
32221210	32221232	6	+	27760321	MOLM13	viability	ATGGCCCTCGAAGCCCGGTGGG	NOTCH4	ENSG00000204301	0.9561123079858047	[555,540]	[1291,13]	6	hSpCas9	negative selection	5424573
32195994	32196017	6	+	27661255	K562	viability	GCAGCGTCAGCAGATCCCAGTGG	NOTCH4	ENSG00000204301	-0.017403794736105427	[1091,1276]	[1084,801]	0	dCas9-KRAB	negative selection	5497109
32196003	32196026	6	+	27661255	K562	viability	GCAGATCCCAGTGGTTACGTTGG	NOTCH4	ENSG00000204301	0.02802854329973492	[520,556]	[519,368]	0	dCas9-KRAB	negative selection	5497110
32196163	32196186	6	+	27661255	K562	viability	GCCAGGGCCGATATCAGGGAAGG	NOTCH4	ENSG00000204301	0.22552372611247384	[305,346]	[354,260]	7	dCas9-KRAB	negative selection	5497111
32196354	32196377	6	+	27661255	K562	viability	GGCCTGGAGAAGCGAGCGGGCGG	NOTCH4	ENSG00000204301	0.16881543059928733	[674,673]	[609,601]	6	dCas9-KRAB	negative selection	5497112
32196372	32196395	6	+	27661255	K562	viability	GGCGGCTCGGGCGTTGTTCACGG	NOTCH4	ENSG00000204301	0.3362037442008163	[462,555]	[476,541]	9	dCas9-KRAB	negative selection	5497113
32223605	32223628	6	+	27661255	K562	viability	GCTGACGAGGTTCTTCCTGGAGG	NOTCH4	ENSG00000204301	0.008530808517651617	[860,853]	[754,632]	0	dCas9-KRAB	negative selection	5497114
32223975	32223998	6	+	27661255	K562	viability	GGGACCCTCAGAGCTCTCACTGG	NOTCH4	ENSG00000204301	-0.4129336654382767	[194,221]	[140,110]	-7	dCas9-KRAB	negative selection	5497115
32196213	32196236	6	-	27661255	K562	viability	GCCAGTGGTCGCGCAAGTGAAGG	NOTCH4	ENSG00000204301	0.20790495175646928	[315,225]	[284,222]	7	dCas9-KRAB	negative selection	5497116
32223855	32223878	6	-	27661255	K562	viability	GTCTCAGTGGTCAGACCCAGAGG	NOTCH4	ENSG00000204301	-0.03734090588875838	[1217,1246]	[1033,894]	-1	dCas9-KRAB	negative selection	5497117
32222769	32222792	6	+	27260156	BXPC3	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.16028094935119142	[506]	[495,527,567,814]	3	hSpCas9	negative selection	5558467
32220815	32220838	6	-	27260156	BXPC3	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.19234155676629833	[417]	[489,434,527,552]	4	hSpCas9	negative selection	5558468
32222732	32222755	6	-	27260156	BXPC3	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.0718959087664447	[306]	[288,275,416,380]	1	hSpCas9	negative selection	5558469
32220845	32220868	6	+	27260156	BXPC3	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.25592988495885277	[493]	[639,593,563,668]	5	hSpCas9	negative selection	5622724
32223047	32223070	6	-	27260156	BXPC3	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.21160149559220548	[437]	[416,290,468,408]	-5	hSpCas9	negative selection	5622725
32223009	32223032	6	+	27260156	BXPC3	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.22420847471269056	[234]	[342,242,212,349]	5	hSpCas9	negative selection	5622726
32222769	32222792	6	+	27260156	A673	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.03784596544701008	[506]	[701,622,617,560]	0	hSpCas9	negative selection	5679718
32220815	32220838	6	-	27260156	A673	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.18677874643141	[417]	[684,522,516,573]	4	hSpCas9	negative selection	5679719
32222732	32222755	6	-	27260156	A673	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.13410490785635687	[306]	[457,483,371,301]	3	hSpCas9	negative selection	5679720
32220845	32220868	6	+	27260156	A673	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.11995830430018732	[493]	[638,696,572,667]	3	hSpCas9	negative selection	5743975
32223047	32223070	6	-	27260156	A673	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.03960333899520632	[437]	[473,413,448,718]	-1	hSpCas9	negative selection	5743976
32223009	32223032	6	+	27260156	A673	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.35388833845541035	[234]	[319,362,373,380]	7	hSpCas9	negative selection	5743977
32222769	32222792	6	+	27260156	A375	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.12633565715019043	[506]	[442,643,483,602]	-2	hSpCas9	negative selection	5800969
32220815	32220838	6	-	27260156	A375	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.8688478131518769	[417]	[1040,996,744,805]	9	hSpCas9	negative selection	5800970
32222732	32222755	6	-	27260156	A375	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.25052005941552774	[306]	[507,376,429,387]	3	hSpCas9	negative selection	5800971
32220845	32220868	6	+	27260156	A375	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.242001824234007	[493]	[617,991,408,742]	3	hSpCas9	negative selection	5865226
32223047	32223070	6	-	27260156	A375	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.06110167176184886	[437]	[461,526,554,427]	-1	hSpCas9	negative selection	5865227
32223009	32223032	6	+	27260156	A375	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.04201206821541503	[234]	[422,320,204,196]	0	hSpCas9	negative selection	5865228
32222769	32222792	6	+	27260156	COLO741	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.04945203332791476	[506]	[672,723,616]	1	hSpCas9	negative selection	5922220
32220815	32220838	6	-	27260156	COLO741	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.4379138355156431	[417]	[830,612,732]	8	hSpCas9	negative selection	5922221
32222732	32222755	6	-	27260156	COLO741	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.2789967673797993	[306]	[353,312,305]	-5	hSpCas9	negative selection	5922222
32220845	32220868	6	+	27260156	COLO741	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.2239684388654684	[493]	[740,700,765]	5	hSpCas9	negative selection	5986477
32223047	32223070	6	-	27260156	COLO741	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.19966356743920594	[437]	[507,626,338]	-4	hSpCas9	negative selection	5986478
32223009	32223032	6	+	27260156	COLO741	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.01612238544793476	[234]	[328,316,268]	0	hSpCas9	negative selection	5986479
32222769	32222792	6	+	27260156	CAL120	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.18981166750656725	[506]	[802,298,593]	-3	hSpCas9	negative selection	6043471
32220815	32220838	6	-	27260156	CAL120	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.27056266842837867	[417]	[565,743,563]	4	hSpCas9	negative selection	6043472
32222732	32222755	6	-	27260156	CAL120	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.23671493932138504	[306]	[607,315,449]	3	hSpCas9	negative selection	6043473
32220845	32220868	6	+	27260156	CAL120	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.5485823000657446	[493]	[1262,602,885]	7	hSpCas9	negative selection	6107728
32223047	32223070	6	-	27260156	CAL120	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.02536787670915988	[437]	[820,384,444]	0	hSpCas9	negative selection	6107729
32223009	32223032	6	+	27260156	CAL120	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.03798491254559577	[234]	[231,284,371]	0	hSpCas9	negative selection	6107730
32222769	32222792	6	+	27260156	CADOES1	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.17496668997851955	[506]	[428,363,321,560]	-3	hSpCas9	negative selection	6164722
32220815	32220838	6	-	27260156	CADOES1	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.5697186120009367	[417]	[545,662,479,620]	8	hSpCas9	negative selection	6164723
32222732	32222755	6	-	27260156	CADOES1	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.3948694746013265	[306]	[268,481,379,370]	6	hSpCas9	negative selection	6164724
32220845	32220868	6	+	27260156	CADOES1	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.3010230450429635	[493]	[555,576,494,638]	5	hSpCas9	negative selection	6228979
32223047	32223070	6	-	27260156	CADOES1	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.025479748609114977	[437]	[331,452,395,420]	0	hSpCas9	negative selection	6228980
32223009	32223032	6	+	27260156	CADOES1	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.048469580327488604	[234]	[149,198,271,224]	-1	hSpCas9	negative selection	6228981
32222769	32222792	6	+	27260156	EWS502	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.020416783803976823	[506]	[496,677,465,533]	0	hSpCas9	negative selection	6285973
32220815	32220838	6	-	27260156	EWS502	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.33793882860123226	[417]	[413,519,689,638]	6	hSpCas9	negative selection	6285974
32222732	32222755	6	-	27260156	EWS502	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.1372017836671794	[306]	[234,260,363,333]	-2	hSpCas9	negative selection	6285975
32220845	32220868	6	+	27260156	EWS502	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.33151551474459906	[493]	[815,443,578,789]	6	hSpCas9	negative selection	6350230
32223047	32223070	6	-	27260156	EWS502	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.23152374003844362	[437]	[413,384,317,463]	-4	hSpCas9	negative selection	6350231
32223009	32223032	6	+	27260156	EWS502	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.271930242782337	[234]	[326,240,293,340]	5	hSpCas9	negative selection	6350232
32222769	32222792	6	+	27260156	EW8	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.026985224900835297	[506]	[603,306,360,430]	0	hSpCas9	negative selection	6407224
32220815	32220838	6	-	27260156	EW8	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.1433804857605981	[417]	[376,306,393,413]	2	hSpCas9	negative selection	6407225
32222732	32222755	6	-	27260156	EW8	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.12550568749722235	[306]	[240,217,257,190]	-2	hSpCas9	negative selection	6407226
32220845	32220868	6	+	27260156	EW8	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.049211476870252846	[493]	[503,468,451,234]	0	hSpCas9	negative selection	6471481
32223047	32223070	6	-	27260156	EW8	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.33948855877019496	[437]	[241,251,266,357]	-6	hSpCas9	negative selection	6471482
32223009	32223032	6	+	27260156	EW8	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.08021472371884042	[234]	[239,156,165,165]	-1	hSpCas9	negative selection	6471483
32222769	32222792	6	+	27260156	CORL105	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.048071005786283066	[506]	[498,683,601,661]	0	hSpCas9	negative selection	6528475
32220815	32220838	6	-	27260156	CORL105	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.5576183904920277	[417]	[769,678,799,646]	8	hSpCas9	negative selection	6528476
32222732	32222755	6	-	27260156	CORL105	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.02758307695535711	[306]	[268,319,442,389]	0	hSpCas9	negative selection	6528477
32220845	32220868	6	+	27260156	CORL105	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.19451171117307603	[493]	[640,575,933,539]	3	hSpCas9	negative selection	6592732
32223047	32223070	6	-	27260156	CORL105	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.30941382427055003	[437]	[417,323,522,408]	-5	hSpCas9	negative selection	6592733
32223009	32223032	6	+	27260156	CORL105	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.056908277135550134	[234]	[264,185,308,388]	1	hSpCas9	negative selection	6592734
32222769	32222792	6	+	27260156	HS294T	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.4895740402103194	[506]	[112,134,131,188]	-6	hSpCas9	negative selection	6649726
32220815	32220838	6	-	27260156	HS294T	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	1.0691497467063873	[417]	[309,564,202,258]	9	hSpCas9	negative selection	6649727
32222732	32222755	6	-	27260156	HS294T	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.0016710964671819983	[306]	[77,182,118,90]	0	hSpCas9	negative selection	6649728
32220845	32220868	6	+	27260156	HS294T	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.2947966015163427	[493]	[200,281,240,209]	4	hSpCas9	negative selection	6713983
32223047	32223070	6	-	27260156	HS294T	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	0.15171887845580734	[437]	[204,102,107,366]	2	hSpCas9	negative selection	6713984
32223009	32223032	6	+	27260156	HS294T	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.15822376367209423	[234]	[63,82,78,104]	-2	hSpCas9	negative selection	6713985
32222769	32222792	6	+	27260156	HCC44	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.6343677480887411	[506]	[478,395,393,220]	-7	hSpCas9	negative selection	6770977
32220815	32220838	6	-	27260156	HCC44	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.6168518337501401	[417]	[694,621,1018,623]	8	hSpCas9	negative selection	6770978
32222732	32222755	6	-	27260156	HCC44	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.18966251843294457	[306]	[319,253,386,277]	-3	hSpCas9	negative selection	6770979
32220845	32220868	6	+	27260156	HCC44	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.3081019109596333	[493]	[618,545,1067,609]	5	hSpCas9	negative selection	6835234
32223047	32223070	6	-	27260156	HCC44	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.2519714697823709	[437]	[490,386,351,429]	-4	hSpCas9	negative selection	6835235
32223009	32223032	6	+	27260156	HCC44	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.09271789250961304	[234]	[311,320,323,181]	1	hSpCas9	negative selection	6835236
32222769	32222792	6	+	27260156	G402	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.19695407852518088	[506]	[568,727,337,536]	-2	hSpCas9	negative selection	6892228
32220815	32220838	6	-	27260156	G402	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.2703612010336615	[417]	[671,446,558,770]	3	hSpCas9	negative selection	6892229
32222732	32222755	6	-	27260156	G402	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.2379601507284883	[306]	[501,536,539,211]	3	hSpCas9	negative selection	6892230
32220845	32220868	6	+	27260156	G402	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	-0.25495189575004223	[493]	[452,665,429,472]	-3	hSpCas9	negative selection	6956485
32223047	32223070	6	-	27260156	G402	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	0.13130876617270565	[437]	[458,622,821,426]	1	hSpCas9	negative selection	6956486
32223009	32223032	6	+	27260156	G402	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.2965752153677823	[234]	[265,460,273,397]	4	hSpCas9	negative selection	6956487
32222769	32222792	6	+	27260156	L33	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.025915753821787096	[506]	[488,230,320,501]	0	hSpCas9	negative selection	7013479
32220815	32220838	6	-	27260156	L33	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.5135289654072235	[417]	[631,271,380,484]	8	hSpCas9	negative selection	7013480
32222732	32222755	6	-	27260156	L33	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.14291344392375516	[306]	[293,112,184,247]	-3	hSpCas9	negative selection	7013481
32220845	32220868	6	+	27260156	L33	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.05507775778545616	[493]	[416,219,274,661]	1	hSpCas9	negative selection	7077736
32223047	32223070	6	-	27260156	L33	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.17795311810450293	[437]	[303,160,299,376]	-4	hSpCas9	negative selection	7077737
32223009	32223032	6	+	27260156	L33	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.15434621055378805	[234]	[201,80,166,179]	-4	hSpCas9	negative selection	7077738
32222769	32222792	6	+	27260156	K562	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.9731242801034432	[506]	[333,172,218,198]	-8	hSpCas9	negative selection	7134730
32220815	32220838	6	-	27260156	K562	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	-0.13750518454152577	[417]	[343,595,191,240]	-2	hSpCas9	negative selection	7134731
32222732	32222755	6	-	27260156	K562	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.9767953876132416	[306]	[527,715,151,731]	9	hSpCas9	negative selection	7134732
32220845	32220868	6	+	27260156	K562	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.06730812489039863	[493]	[702,698,318,179]	0	hSpCas9	negative selection	7198987
32223047	32223070	6	-	27260156	K562	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	0.03685130456006579	[437]	[494,460,320,334]	0	hSpCas9	negative selection	7198988
32223009	32223032	6	+	27260156	K562	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.48123002022392125	[234]	[144,264,121,78]	-5	hSpCas9	negative selection	7198989
32222769	32222792	6	+	27260156	HT29	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.06023259382334925	[506]	[659,588,711,605]	1	hSpCas9	negative selection	7255981
32220815	32220838	6	-	27260156	HT29	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.5054078483385159	[417]	[740,740,893,530]	8	hSpCas9	negative selection	7255982
32222732	32222755	6	-	27260156	HT29	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.013084192985377108	[306]	[388,403,346,367]	0	hSpCas9	negative selection	7255983
32220845	32220868	6	+	27260156	HT29	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.2058079768086415	[493]	[622,669,852,620]	4	hSpCas9	negative selection	7320238
32223047	32223070	6	-	27260156	HT29	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.0741120782631342	[437]	[578,570,431,454]	-1	hSpCas9	negative selection	7320239
32223009	32223032	6	+	27260156	HT29	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.13148445556914057	[234]	[387,320,243,303]	2	hSpCas9	negative selection	7320240
32222769	32222792	6	+	27260156	MHHES1	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.10933698940801465	[506]	[534,749,496,659]	2	hSpCas9	negative selection	7377232
32220815	32220838	6	-	27260156	MHHES1	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.5905043077400892	[417]	[771,891,659,556]	8	hSpCas9	negative selection	7377233
32222732	32222755	6	-	27260156	MHHES1	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.00812851463623221	[306]	[315,582,321,200]	0	hSpCas9	negative selection	7377234
32220845	32220868	6	+	27260156	MHHES1	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.2063854317782325	[493]	[765,904,804,219]	4	hSpCas9	negative selection	7441489
32223047	32223070	6	-	27260156	MHHES1	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	0.29520015808117794	[437]	[690,904,686,249]	5	hSpCas9	negative selection	7441490
32223009	32223032	6	+	27260156	MHHES1	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.3672786838677554	[234]	[371,384,391,240]	6	hSpCas9	negative selection	7441491
32222769	32222792	6	+	27260156	MEWO	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.2821557216705674	[506]	[508,393,814]	6	hSpCas9	negative selection	7498483
32220815	32220838	6	-	27260156	MEWO	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.32610899722545894	[417]	[505,426,540]	7	hSpCas9	negative selection	7498484
32222732	32222755	6	-	27260156	MEWO	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.3958166097711746	[306]	[327,240,106]	-7	hSpCas9	negative selection	7498485
32220845	32220868	6	+	27260156	MEWO	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.3069171637060247	[493]	[663,558,509]	6	hSpCas9	negative selection	7562740
32223047	32223070	6	-	27260156	MEWO	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.17312147281184842	[437]	[371,341,377]	-4	hSpCas9	negative selection	7562741
32223009	32223032	6	+	27260156	MEWO	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.43320588518645287	[234]	[226,138,134]	-7	hSpCas9	negative selection	7562742
32222769	32222792	6	+	27260156	LNCAPCLONEFGC	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.10646810400041498	[506]	[399,519,658,422]	1	hSpCas9	negative selection	7619734
32220815	32220838	6	-	27260156	LNCAPCLONEFGC	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.5899133439883943	[417]	[622,463,594,606]	8	hSpCas9	negative selection	7619735
32222732	32222755	6	-	27260156	LNCAPCLONEFGC	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.5416564772344367	[306]	[432,353,439,399]	8	hSpCas9	negative selection	7619736
32220845	32220868	6	+	27260156	LNCAPCLONEFGC	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.3871400659343291	[493]	[551,512,652,637]	6	hSpCas9	negative selection	7683991
32223047	32223070	6	-	27260156	LNCAPCLONEFGC	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.39121281991347845	[437]	[203,265,401,356]	-6	hSpCas9	negative selection	7683992
32223009	32223032	6	+	27260156	LNCAPCLONEFGC	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.09161811834702505	[234]	[118,209,358,241]	1	hSpCas9	negative selection	7683993
32222769	32222792	6	+	27260156	PANC0327	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.16750052753153621	[506]	[708,448,422,465]	2	hSpCas9	negative selection	7740985
32220815	32220838	6	-	27260156	PANC0327	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.5429539814107843	[417]	[494,547,507,607]	7	hSpCas9	negative selection	7740986
32222732	32222755	6	-	27260156	PANC0327	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.5751520454793752	[306]	[311,594,387,297]	8	hSpCas9	negative selection	7740987
32220845	32220868	6	+	27260156	PANC0327	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.4493785258980153	[493]	[334,508,876,665]	6	hSpCas9	negative selection	7805242
32223047	32223070	6	-	27260156	PANC0327	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.7466213597981648	[437]	[252,232,192,249]	-7	hSpCas9	negative selection	7805243
32223009	32223032	6	+	27260156	PANC0327	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.12448690205446633	[234]	[195,130,236,355]	1	hSpCas9	negative selection	7805244
32222769	32222792	6	+	27260156	NCIH2009	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.10179105765258292	[506]	[961,651,706]	1	hSpCas9	negative selection	7862236
32220815	32220838	6	-	27260156	NCIH2009	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.7643125817871069	[417]	[1230,798,994]	9	hSpCas9	negative selection	7862237
32222732	32222755	6	-	27260156	NCIH2009	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.31622743035097295	[306]	[531,358,712]	4	hSpCas9	negative selection	7862238
32220845	32220868	6	+	27260156	NCIH2009	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.12638902920968603	[493]	[957,440,905]	1	hSpCas9	negative selection	7926493
32223047	32223070	6	-	27260156	NCIH2009	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.5043224446730346	[437]	[424,390,476]	-6	hSpCas9	negative selection	7926494
32223009	32223032	6	+	27260156	NCIH2009	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.07282721027837835	[234]	[368,294,376]	1	hSpCas9	negative selection	7926495
32222769	32222792	6	+	27260156	NCIH1373	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-1.3651532683141643	[506]	[152,130,347,64]	-8	hSpCas9	negative selection	7983487
32220815	32220838	6	-	27260156	NCIH1373	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.1644787042300847	[417]	[655,538,503,107]	1	hSpCas9	negative selection	7983488
32222732	32222755	6	-	27260156	NCIH1373	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.1083450466273681	[306]	[761,271,322,48]	1	hSpCas9	negative selection	7983489
32220845	32220868	6	+	27260156	NCIH1373	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	-0.17471729058352434	[493]	[557,338,557,139]	-2	hSpCas9	negative selection	8047744
32223047	32223070	6	-	27260156	NCIH1373	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.7412577356512031	[437]	[292,223,438,56]	-6	hSpCas9	negative selection	8047745
32223009	32223032	6	+	27260156	NCIH1373	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.195526393675459	[234]	[254,133,250,77]	-2	hSpCas9	negative selection	8047746
32222769	32222792	6	+	27260156	PATU8902	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.19170163028019582	[506]	[486,531,477,1061]	-2	hSpCas9	negative selection	8104738
32220815	32220838	6	-	27260156	PATU8902	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.7933193613749937	[417]	[740,855,892,1646]	8	hSpCas9	negative selection	8104739
32222732	32222755	6	-	27260156	PATU8902	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.5084674709792816	[306]	[799,585,536,508]	5	hSpCas9	negative selection	8104740
32220845	32220868	6	+	27260156	PATU8902	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.8957374194686255	[493]	[1960,1197,631,1504]	8	hSpCas9	negative selection	8168995
32223047	32223070	6	-	27260156	PATU8902	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.2215074036957667	[437]	[423,330,516,858]	-2	hSpCas9	negative selection	8168996
32223009	32223032	6	+	27260156	PATU8902	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.43866435999290776	[234]	[348,305,340,850]	4	hSpCas9	negative selection	8168997
32222769	32222792	6	+	27260156	PANC1	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.41565961506223015	[506]	[322,482,241,289]	-6	hSpCas9	negative selection	8225989
32220815	32220838	6	-	27260156	PANC1	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.2811882978267465	[417]	[349,649,492,311]	4	hSpCas9	negative selection	8225990
32222732	32222755	6	-	27260156	PANC1	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.24772071423567749	[306]	[305,507,178,295]	4	hSpCas9	negative selection	8225991
32220845	32220868	6	+	27260156	PANC1	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.37025978020955885	[493]	[559,780,503,409]	6	hSpCas9	negative selection	8290246
32223047	32223070	6	-	27260156	PANC1	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	0.016586974979514557	[437]	[381,611,393,204]	0	hSpCas9	negative selection	8290247
32223009	32223032	6	+	27260156	PANC1	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.27199551542902434	[234]	[201,173,161,133]	-4	hSpCas9	negative selection	8290248
32222769	32222792	6	+	27260156	PANC0813	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.13859882273118518	[506]	[550,572,416,617]	-2	hSpCas9	negative selection	8347240
32220815	32220838	6	-	27260156	PANC0813	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.5537213261640259	[417]	[795,814,490,781]	8	hSpCas9	negative selection	8347241
32222732	32222755	6	-	27260156	PANC0813	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.11877873550345913	[306]	[492,422,277,380]	2	hSpCas9	negative selection	8347242
32220845	32220868	6	+	27260156	PANC0813	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	-0.010342819388238389	[493]	[572,488,566,668]	0	hSpCas9	negative selection	8411497
32223047	32223070	6	-	27260156	PANC0813	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	0.18142946975564317	[437]	[603,623,550,556]	3	hSpCas9	negative selection	8411498
32223009	32223032	6	+	27260156	PANC0813	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.4824727149527165	[234]	[416,500,237,387]	7	hSpCas9	negative selection	8411499
32222769	32222792	6	+	27260156	RDES	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.14947969532140945	[506]	[307,490,695,673]	-2	hSpCas9	negative selection	8468491
32220815	32220838	6	-	27260156	RDES	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.8891979225175223	[417]	[799,779,954,1055]	9	hSpCas9	negative selection	8468492
32222732	32222755	6	-	27260156	RDES	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.015051181555349569	[306]	[261,417,310,416]	0	hSpCas9	negative selection	8468493
32220845	32220868	6	+	27260156	RDES	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.12940351622249002	[493]	[510,478,718,831]	2	hSpCas9	negative selection	8532748
32223047	32223070	6	-	27260156	RDES	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.5095008672639871	[437]	[263,331,389,457]	-7	hSpCas9	negative selection	8532749
32223009	32223032	6	+	27260156	RDES	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.3521658732989782	[234]	[284,265,471,376]	5	hSpCas9	negative selection	8532750
32222769	32222792	6	+	27260156	PC3	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.012107594611888386	[506]	[393,469,771,496]	0	hSpCas9	negative selection	8589742
32220815	32220838	6	-	27260156	PC3	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.16494706173158843	[417]	[241,588,771,434]	3	hSpCas9	negative selection	8589743
32222732	32222755	6	-	27260156	PC3	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.10337997694962564	[306]	[141,317,719,347]	2	hSpCas9	negative selection	8589744
32220845	32220868	6	+	27260156	PC3	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	-0.0695250178277518	[493]	[365,374,769,478]	-1	hSpCas9	negative selection	8653999
32223047	32223070	6	-	27260156	PC3	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.1716764337311703	[437]	[192,365,793,412]	-4	hSpCas9	negative selection	8654000
32223009	32223032	6	+	27260156	PC3	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.5389276051450007	[234]	[281,224,467,429]	9	hSpCas9	negative selection	8654001
32222769	32222792	6	+	27260156	PATU8988T	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.0648226931509081	[506]	[292,613,494,669]	1	hSpCas9	negative selection	8710993
32220815	32220838	6	-	27260156	PATU8988T	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.46564317549417933	[417]	[451,606,605,570]	7	hSpCas9	negative selection	8710994
32222732	32222755	6	-	27260156	PATU8988T	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.27573475137553893	[306]	[229,420,413,377]	5	hSpCas9	negative selection	8710995
32220845	32220868	6	+	27260156	PATU8988T	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.27065758379435506	[493]	[473,599,502,742]	4	hSpCas9	negative selection	8775250
32223047	32223070	6	-	27260156	PATU8988T	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.26526567661349665	[437]	[535,376,223,268]	-4	hSpCas9	negative selection	8775251
32223009	32223032	6	+	27260156	PATU8988T	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.1868031295515451	[234]	[240,122,279,140]	-3	hSpCas9	negative selection	8775252
32222769	32222792	6	+	27260156	T47D	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.24210041867600182	[506]	[571,396,477,561]	-5	hSpCas9	negative selection	8832244
32220815	32220838	6	-	27260156	T47D	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.34560517067043056	[417]	[716,536,580,648]	7	hSpCas9	negative selection	8832245
32222732	32222755	6	-	27260156	T47D	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.04791447353037426	[306]	[362,330,347,342]	-1	hSpCas9	negative selection	8832246
32220845	32220868	6	+	27260156	T47D	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.0511526068549666	[493]	[653,575,610,543]	1	hSpCas9	negative selection	8896501
32223047	32223070	6	-	27260156	T47D	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.25887254862582687	[437]	[489,407,407,400]	-5	hSpCas9	negative selection	8896502
32223009	32223032	6	+	27260156	T47D	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.14796101356898972	[234]	[289,249,286,393]	3	hSpCas9	negative selection	8896503
32222769	32222792	6	+	27260156	SU8686	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.7028661319566907	[506]	[292,315,315,308]	-8	hSpCas9	negative selection	8953495
32220815	32220838	6	-	27260156	SU8686	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.44469233815984593	[417]	[578,508,671,487]	7	hSpCas9	negative selection	8953496
32222732	32222755	6	-	27260156	SU8686	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.09801572651740853	[306]	[308,294,197,534]	1	hSpCas9	negative selection	8953497
32220845	32220868	6	+	27260156	SU8686	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	-0.25869122642874903	[493]	[403,317,331,625]	-4	hSpCas9	negative selection	9017752
32223047	32223070	6	-	27260156	SU8686	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.5004224673593054	[437]	[243,331,332,323]	-7	hSpCas9	negative selection	9017753
32223009	32223032	6	+	27260156	SU8686	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	-0.22610995932615507	[234]	[172,131,224,292]	-4	hSpCas9	negative selection	9017754
32222769	32222792	6	+	27260156	SKES1	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.12645131973353457	[506]	[611,573,648,395]	2	hSpCas9	negative selection	9074746
32220815	32220838	6	-	27260156	SKES1	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.49173886022962165	[417]	[700,656,580,441]	8	hSpCas9	negative selection	9074747
32222732	32222755	6	-	27260156	SKES1	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	-0.3798460760912956	[306]	[248,289,150,255]	-7	hSpCas9	negative selection	9074748
32220845	32220868	6	+	27260156	SKES1	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.1983153510539759	[493]	[575,719,575,420]	4	hSpCas9	negative selection	9139003
32223047	32223070	6	-	27260156	SKES1	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.11081425883127916	[437]	[450,470,407,309]	-2	hSpCas9	negative selection	9139004
32223009	32223032	6	+	27260156	SKES1	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.40589316822609145	[234]	[315,208,437,267]	8	hSpCas9	negative selection	9139005
32222769	32222792	6	+	27260156	TOV112D	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	-0.3205121782993524	[506]	[379,603,347,341]	-6	hSpCas9	negative selection	9195997
32220815	32220838	6	-	27260156	TOV112D	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.33812169111458423	[417]	[378,512,592,611]	6	hSpCas9	negative selection	9195998
32222732	32222755	6	-	27260156	TOV112D	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.0936337112267639	[306]	[229,685,268,209]	1	hSpCas9	negative selection	9195999
32220845	32220868	6	+	27260156	TOV112D	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.5563321571378845	[493]	[527,759,694,911]	8	hSpCas9	negative selection	9260254
32223047	32223070	6	-	27260156	TOV112D	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.27536920062781495	[437]	[410,406,237,406]	-5	hSpCas9	negative selection	9260255
32223009	32223032	6	+	27260156	TOV112D	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.20504285901837227	[234]	[314,314,189,278]	4	hSpCas9	negative selection	9260256
32222769	32222792	6	+	27260156	TC71	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.08488444358669012	[506]	[474,539,546,757]	2	hSpCas9	negative selection	9317248
32220815	32220838	6	-	27260156	TC71	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.37326224016758824	[417]	[615,489,631,580]	8	hSpCas9	negative selection	9317249
32222732	32222755	6	-	27260156	TC71	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.07830409602451582	[306]	[292,325,426,341]	2	hSpCas9	negative selection	9317250
32220845	32220868	6	+	27260156	TC71	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.2696036291784526	[493]	[691,645,568,647]	6	hSpCas9	negative selection	9381505
32223047	32223070	6	-	27260156	TC71	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.03812332623726861	[437]	[423,398,524,480]	-1	hSpCas9	negative selection	9381506
32223009	32223032	6	+	27260156	TC71	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.0955999921611318	[234]	[268,427,171,206]	2	hSpCas9	negative selection	9381507
32222769	32222792	6	+	27260156	TC32	viability	GAAACTGGCACGTCTCACCCAGG	NOTCH4	ENSG00000204301	0.2069648959919127	[506]	[478,483,696,565]	4	hSpCas9	negative selection	9438499
32220815	32220838	6	-	27260156	TC32	viability	GTCAGCCACCAGTGTCAGAATGG	NOTCH4	ENSG00000204301	0.4258696001626616	[417]	[456,319,804,641]	7	hSpCas9	negative selection	9438500
32222732	32222755	6	-	27260156	TC32	viability	AACGCCCAGCTCTGCCAAAATGG	NOTCH4	ENSG00000204301	0.1783442329106052	[306]	[299,217,445,391]	3	hSpCas9	negative selection	9438501
32220845	32220868	6	+	27260156	TC32	viability	TCTGGATTCACCTCACAGTCTGG	NOTCH4	ENSG00000204301	0.4000333587865073	[493]	[482,604,728,634]	7	hSpCas9	negative selection	9502756
32223047	32223070	6	-	27260156	TC32	viability	TTCCCAGAACCCTGTGCCAATGG	NOTCH4	ENSG00000204301	-0.019375275603277037	[437]	[400,237,552,504]	0	hSpCas9	negative selection	9502757
32223009	32223032	6	+	27260156	TC32	viability	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.11558572200678552	[234]	[210,144,311,332]	2	hSpCas9	negative selection	9502758
32219747	32219770	6	+	27869803	HPAFII	viability after 27 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	0.5171087385167686	[238]	[283,92,NaN]	4	hSpCas9	negative selection	9595368
32220258	32220281	6	+	27869803	HPAFII	viability after 27 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-0.027869236910656597	[228]	[206,43,NaN]	0	hSpCas9	negative selection	9595369
32220439	32220462	6	+	27869803	HPAFII	viability after 27 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	0.012469351962216102	[5]	[0,4,NaN]	0	hSpCas9	negative selection	9595370
32221129	32221152	6	+	27869803	HPAFII	viability after 27 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	-1.22057031357374	[271]	[38,79,NaN]	-7	hSpCas9	negative selection	9595371
32222644	32222667	6	+	27869803	HPAFII	viability after 27 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.44373147075915836	[215]	[178,133,NaN]	3	hSpCas9	negative selection	9595372
32223009	32223032	6	+	27869803	HPAFII	viability after 27 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.883484875119896	[150]	[200,100,NaN]	7	hSpCas9	negative selection	9595373
32219747	32219770	6	+	27869803	HPAFII	viability after 15 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	0.5587358694731965	[238]	[550,270,NaN]	6	hSpCas9	negative selection	9677817
32220258	32220281	6	+	27869803	HPAFII	viability after 15 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-0.06628154717841006	[228]	[358,157,NaN]	0	hSpCas9	negative selection	9677818
32220439	32220462	6	+	27869803	HPAFII	viability after 15 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	-1.1780643041515644	[5]	[0,3,NaN]	-8	hSpCas9	negative selection	9677819
32221129	32221152	6	+	27869803	HPAFII	viability after 15 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	-0.19538540067362437	[271]	[258,252,NaN]	-2	hSpCas9	negative selection	9677820
32222644	32222667	6	+	27869803	HPAFII	viability after 15 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.3725714367116895	[215]	[413,229,NaN]	4	hSpCas9	negative selection	9677821
32223009	32223032	6	+	27869803	HPAFII	viability after 15 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.6464762513624915	[150]	[393,166,NaN]	7	hSpCas9	negative selection	9677822
32219747	32219770	6	+	27869803	ASPC1	viability after 36 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	0.30835746072321657	[562]	[159,312,243]	3	hSpCas9	negative selection	9760266
32220258	32220281	6	+	27869803	ASPC1	viability after 36 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	0.2261944919394272	[529]	[75,89,412]	2	hSpCas9	negative selection	9760267
32220439	32220462	6	+	27869803	ASPC1	viability after 36 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	0.6461906978521932	[52]	[99,0,0]	6	hSpCas9	negative selection	9760268
32221129	32221152	6	+	27869803	ASPC1	viability after 36 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	-0.16547901050680902	[845]	[213,231,319]	-2	hSpCas9	negative selection	9760269
32222644	32222667	6	+	27869803	ASPC1	viability after 36 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.14029749761666288	[374]	[402,68,20]	1	hSpCas9	negative selection	9760270
32223009	32223032	6	+	27869803	ASPC1	viability after 36 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	1.2090039341722871	[448]	[707,379,101]	9	hSpCas9	negative selection	9760271
32219747	32219770	6	+	27869803	PATU8988S	viability after 35 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	0.4544832025691492	[460]	[218,289,NaN]	5	hSpCas9	negative selection	9842715
32220258	32220281	6	+	27869803	PATU8988S	viability after 35 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	0.06268143525477005	[529]	[194,250,NaN]	0	hSpCas9	negative selection	9842716
32220439	32220462	6	+	27869803	PATU8988S	viability after 35 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	0.30957592729799366	[7]	[0,6,NaN]	3	hSpCas9	negative selection	9842717
32221129	32221152	6	+	27869803	PATU8988S	viability after 35 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.00584641471428593	[770]	[434,187,NaN]	0	hSpCas9	negative selection	9842718
32222644	32222667	6	+	27869803	PATU8988S	viability after 35 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.48430282639512673	[399]	[165,284,NaN]	5	hSpCas9	negative selection	9842719
32223009	32223032	6	+	27869803	PATU8988S	viability after 35 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.44639895276337066	[406]	[162,283,NaN]	5	hSpCas9	negative selection	9842720
32219747	32219770	6	+	27869803	PATU8988S	viability after 31 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	0.42637040910611174	[460]	[184,325,NaN]	5	hSpCas9	negative selection	9925164
32220258	32220281	6	+	27869803	PATU8988S	viability after 31 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	-0.13402957404381272	[529]	[119,284,NaN]	-1	hSpCas9	negative selection	9925165
32220439	32220462	6	+	27869803	PATU8988S	viability after 31 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	-1.6735328085499965	[7]	[0,0,NaN]	-8	hSpCas9	negative selection	9925166
32221129	32221152	6	+	27869803	PATU8988S	viability after 31 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	0.18992058989474414	[770]	[384,306,NaN]	2	hSpCas9	negative selection	9925167
32222644	32222667	6	+	27869803	PATU8988S	viability after 31 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.4675351272438186	[399]	[143,317,NaN]	5	hSpCas9	negative selection	9925168
32223009	32223032	6	+	27869803	PATU8988S	viability after 31 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	0.1769599324982116	[406]	[120,262,NaN]	2	hSpCas9	negative selection	9925169
32219747	32219770	6	+	27869803	HPAFII	viability after 35 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	0.8158242748458214	[238]	[299,114,NaN]	5	hSpCas9	negative selection	10007613
32220258	32220281	6	+	27869803	HPAFII	viability after 35 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	0.5411299429194938	[228]	[258,66,NaN]	3	hSpCas9	negative selection	10007614
32220439	32220462	6	+	27869803	HPAFII	viability after 35 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	-1.6028739477244818	[5]	[0,0,NaN]	-7	hSpCas9	negative selection	10007615
32221129	32221152	6	+	27869803	HPAFII	viability after 35 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	-1.8180725364759343	[271]	[23,55,NaN]	-7	hSpCas9	negative selection	10007616
32222644	32222667	6	+	27869803	HPAFII	viability after 35 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.396967644914296	[215]	[230,45,NaN]	2	hSpCas9	negative selection	10007617
32223009	32223032	6	+	27869803	HPAFII	viability after 35 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	1.1538125125668173	[150]	[226,105,NaN]	7	hSpCas9	negative selection	10007618
32219747	32219770	6	+	27869803	HPAFII	viability after 31 days	CAGGAACCGCCATGTTCACAGGG	NOTCH4	ENSG00000204301	0.7585080202740112	[238]	[291,155,NaN]	5	hSpCas9	negative selection	10090062
32220258	32220281	6	+	27869803	HPAFII	viability after 31 days	ACATGTCTTCCAAGTGGCACAGG	NOTCH4	ENSG00000204301	0.561525974025666	[228]	[293,75,NaN]	4	hSpCas9	negative selection	10090063
32220439	32220462	6	+	27869803	HPAFII	viability after 31 days	GCCCACCCGGTCAATGCAGGTGG	NOTCH4	ENSG00000204301	-0.20844897601936996	[5]	[0,4,NaN]	-1	hSpCas9	negative selection	10090064
32221129	32221152	6	+	27869803	HPAFII	viability after 31 days	GCCCAGGGTGTTATGGCAGGAGG	NOTCH4	ENSG00000204301	-2.1192253187967203	[271]	[26,43,NaN]	-8	hSpCas9	negative selection	10090065
32222644	32222667	6	+	27869803	HPAFII	viability after 31 days	GAGGCAAGTGCACAAGAAGCTGG	NOTCH4	ENSG00000204301	0.7549949252692361	[215]	[250,153,NaN]	5	hSpCas9	negative selection	10090066
32223009	32223032	6	+	27869803	HPAFII	viability after 31 days	AGGTCCCTTGTCCCAGAGACAGG	NOTCH4	ENSG00000204301	1.115332580526747	[150]	[207,156,NaN]	8	hSpCas9	negative selection	10090067
32203776	32203799	6	+	28162770	P31FUJ	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	0.8103656547419952	[213]	[440]	8	hSpCas9	negative selection	10201503
32213154	32213177	6	+	28162770	P31FUJ	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	-0.2633905242478016	[428]	[419]	-3	hSpCas9	negative selection	10201504
32198666	32198689	6	-	28162770	P31FUJ	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-3.857293069322172	[184]	[14]	-9	hSpCas9	negative selection	10201505
32222659	32222682	6	+	28162770	P31FUJ	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	0.673584744814129	[190]	[357]	7	hSpCas9	negative selection	10201506
32221208	32221231	6	+	28162770	P31FUJ	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	0.19305826415900132	[165]	[222]	2	hSpCas9	negative selection	10201507
32221114	32221137	6	+	28162770	P31FUJ	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-0.6444331022499727	[140]	[105]	-5	hSpCas9	negative selection	10201508
32220985	32221008	6	+	28162770	P31FUJ	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	-0.8084612502454432	[540]	[362]	-6	hSpCas9	negative selection	10201509
32220135	32220158	6	+	28162770	P31FUJ	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.47756042250702047	[612]	[1002]	5	hSpCas9	negative selection	10201510
32217035	32217058	6	-	28162770	P31FUJ	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	0.5321389624130127	[142]	[242]	6	hSpCas9	negative selection	10201511
32216955	32216978	6	+	28162770	P31FUJ	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	0.6814679215597373	[155]	[293]	7	hSpCas9	negative selection	10201512
32203776	32203799	6	+	28162770	TF1	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10370869
32213154	32213177	6	+	28162770	TF1	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	NaN	[NaN]	[230]	1	hSpCas9	negative selection	10370870
32198666	32198689	6	-	28162770	TF1	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10370871
32222659	32222682	6	+	28162770	TF1	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	NaN	[NaN]	[170]	1	hSpCas9	negative selection	10370872
32221208	32221231	6	+	28162770	TF1	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	NaN	[NaN]	[58]	1	hSpCas9	negative selection	10370873
32221114	32221137	6	+	28162770	TF1	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10370874
32220985	32221008	6	+	28162770	TF1	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	NaN	[NaN]	[117]	1	hSpCas9	negative selection	10370875
32220135	32220158	6	+	28162770	TF1	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	NaN	[NaN]	[574]	1	hSpCas9	negative selection	10370876
32217035	32217058	6	-	28162770	TF1	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10370877
32216955	32216978	6	+	28162770	TF1	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	NaN	[NaN]	[179]	1	hSpCas9	negative selection	10370878
32203776	32203799	6	+	28162770	SKM1	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	0.23533147704394614	[73]	[153]	2	hSpCas9	negative selection	10540235
32213154	32213177	6	+	28162770	SKM1	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	-0.20902482113125276	[101]	[155]	-2	hSpCas9	negative selection	10540236
32198666	32198689	6	-	28162770	SKM1	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-6.654891712186747	[56]	[0]	-9	hSpCas9	negative selection	10540237
32222659	32222682	6	+	28162770	SKM1	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	0.6432905720365343	[66]	[184]	6	hSpCas9	negative selection	10540238
32221208	32221231	6	+	28162770	SKM1	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	0.29901370293936036	[39]	[86]	3	hSpCas9	negative selection	10540239
32221114	32221137	6	+	28162770	SKM1	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-1.0255350921071378	[37]	[32]	-6	hSpCas9	negative selection	10540240
32220985	32221008	6	+	28162770	SKM1	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	1.1999130784064351	[97]	[397]	9	hSpCas9	negative selection	10540241
32220135	32220158	6	+	28162770	SKM1	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.3412841060572718	[120]	[270]	3	hSpCas9	negative selection	10540242
32217035	32217058	6	-	28162770	SKM1	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	-0.5171471164935846	[50]	[62]	-4	hSpCas9	negative selection	10540243
32216955	32216978	6	+	28162770	SKM1	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	0.8000501214343708	[63]	[196]	7	hSpCas9	negative selection	10540244
32203776	32203799	6	+	28162770	SKM1	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	0.23533147704394614	[73]	[153]	2	hSpCas9	negative selection	10709601
32213154	32213177	6	+	28162770	SKM1	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	-0.20902482113125276	[101]	[155]	-2	hSpCas9	negative selection	10709602
32198666	32198689	6	-	28162770	SKM1	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-6.654891712186747	[56]	[0]	-9	hSpCas9	negative selection	10709603
32222659	32222682	6	+	28162770	SKM1	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	0.6432905720365343	[66]	[184]	6	hSpCas9	negative selection	10709604
32221208	32221231	6	+	28162770	SKM1	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	0.29901370293936036	[39]	[86]	3	hSpCas9	negative selection	10709605
32221114	32221137	6	+	28162770	SKM1	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-1.0255350921071378	[37]	[32]	-6	hSpCas9	negative selection	10709606
32220985	32221008	6	+	28162770	SKM1	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	1.1999130784064351	[97]	[397]	9	hSpCas9	negative selection	10709607
32220135	32220158	6	+	28162770	SKM1	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.3412841060572718	[120]	[270]	3	hSpCas9	negative selection	10709608
32217035	32217058	6	-	28162770	SKM1	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	-0.5171471164935846	[50]	[62]	-4	hSpCas9	negative selection	10709609
32216955	32216978	6	+	28162770	SKM1	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	0.8000501214343708	[63]	[196]	7	hSpCas9	negative selection	10709610
32203776	32203799	6	+	28162770	PL21	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	0.5077641713471842	[222]	[137]	4	hSpCas9	negative selection	10878967
32213154	32213177	6	+	28162770	PL21	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	0.14980793893917554	[349]	[168]	1	hSpCas9	negative selection	10878968
32198666	32198689	6	-	28162770	PL21	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-5.587762944902112	[220]	[1]	-9	hSpCas9	negative selection	10878969
32222659	32222682	6	+	28162770	PL21	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	0.023261852405240813	[155]	[68]	0	hSpCas9	negative selection	10878970
32221208	32221231	6	+	28162770	PL21	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	0.3819779374751331	[133]	[75]	3	hSpCas9	negative selection	10878971
32221114	32221137	6	+	28162770	PL21	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-0.6989314766598992	[137]	[36]	-5	hSpCas9	negative selection	10878972
32220985	32221008	6	+	28162770	PL21	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	0.39401934808335515	[291]	[166]	3	hSpCas9	negative selection	10878973
32220135	32220158	6	+	28162770	PL21	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	-0.052626455890646406	[447]	[187]	0	hSpCas9	negative selection	10878974
32217035	32217058	6	-	28162770	PL21	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	1.615177113768164	[80]	[107]	9	hSpCas9	negative selection	10878975
32216955	32216978	6	+	28162770	PL21	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	-0.5215592230235755	[187]	[56]	-4	hSpCas9	negative selection	10878976
32203776	32203799	6	+	28162770	P31FUJ	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	0.8103656547419952	[213]	[440]	8	hSpCas9	negative selection	11048333
32213154	32213177	6	+	28162770	P31FUJ	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	-0.2633905242478016	[428]	[419]	-3	hSpCas9	negative selection	11048334
32198666	32198689	6	-	28162770	P31FUJ	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-3.857293069322172	[184]	[14]	-9	hSpCas9	negative selection	11048335
32222659	32222682	6	+	28162770	P31FUJ	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	0.673584744814129	[190]	[357]	7	hSpCas9	negative selection	11048336
32221208	32221231	6	+	28162770	P31FUJ	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	0.19305826415900132	[165]	[222]	2	hSpCas9	negative selection	11048337
32221114	32221137	6	+	28162770	P31FUJ	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-0.6444331022499727	[140]	[105]	-5	hSpCas9	negative selection	11048338
32220985	32221008	6	+	28162770	P31FUJ	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	-0.8084612502454432	[540]	[362]	-6	hSpCas9	negative selection	11048339
32220135	32220158	6	+	28162770	P31FUJ	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.47756042250702047	[612]	[1002]	5	hSpCas9	negative selection	11048340
32217035	32217058	6	-	28162770	P31FUJ	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	0.5321389624130127	[142]	[242]	6	hSpCas9	negative selection	11048341
32216955	32216978	6	+	28162770	P31FUJ	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	0.6814679215597373	[155]	[293]	7	hSpCas9	negative selection	11048342
32203776	32203799	6	+	28162770	OCIAML5	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	0.5450043818853978	[100]	[265]	5	hSpCas9	negative selection	11217699
32213154	32213177	6	+	28162770	OCIAML5	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	0.25296889983429205	[191]	[412]	2	hSpCas9	negative selection	11217700
32198666	32198689	6	-	28162770	OCIAML5	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-1.4103611211230733	[133]	[90]	-7	hSpCas9	negative selection	11217701
32222659	32222682	6	+	28162770	OCIAML5	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	0.018853479971073187	[110]	[202]	0	hSpCas9	negative selection	11217702
32221208	32221231	6	+	28162770	OCIAML5	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	1.0424403002886893	[77]	[289]	8	hSpCas9	negative selection	11217703
32221114	32221137	6	+	28162770	OCIAML5	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	0.12856810426907206	[74]	[147]	1	hSpCas9	negative selection	11217704
32220985	32221008	6	+	28162770	OCIAML5	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	-0.6778920964203268	[225]	[254]	-4	hSpCas9	negative selection	11217705
32220135	32220158	6	+	28162770	OCIAML5	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.1458650487947737	[348]	[696]	1	hSpCas9	negative selection	11217706
32217035	32217058	6	-	28162770	OCIAML5	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	0.2621906083936829	[90]	[196]	2	hSpCas9	negative selection	11217707
32216955	32216978	6	+	28162770	OCIAML5	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	0.16695825481775922	[112]	[228]	1	hSpCas9	negative selection	11217708
32203776	32203799	6	+	28162770	EOL1	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	-0.19589000675113521	[436]	[200]	-1	hSpCas9	negative selection	11387065
32213154	32213177	6	+	28162770	EOL1	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	1.4214622779037862	[410]	[579]	9	hSpCas9	negative selection	11387066
32198666	32198689	6	-	28162770	EOL1	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-6.108875229966916	[392]	[2]	-9	hSpCas9	negative selection	11387067
32222659	32222682	6	+	28162770	EOL1	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	-0.47723363100604244	[324]	[122]	-4	hSpCas9	negative selection	11387068
32221208	32221231	6	+	28162770	EOL1	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	1.4222471258358966	[300]	[424]	9	hSpCas9	negative selection	11387069
32221114	32221137	6	+	28162770	EOL1	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-0.008338032570928383	[272]	[142]	0	hSpCas9	negative selection	11387070
32220985	32221008	6	+	28162770	EOL1	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	-0.8665867980287392	[397]	[114]	-6	hSpCas9	negative selection	11387071
32220135	32220158	6	+	28162770	EOL1	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.04492432505323363	[700]	[380]	0	hSpCas9	negative selection	11387072
32217035	32217058	6	-	28162770	EOL1	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	-1.2150035808282589	[140]	[31]	-7	hSpCas9	negative selection	11387073
32216955	32216978	6	+	28162770	EOL1	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	1.0663550979096958	[212]	[234]	8	hSpCas9	negative selection	11387074
32203776	32203799	6	+	28162770	MOLM13	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	-0.05540100838628831	[331]	[230]	0	hSpCas9	negative selection	11556431
32213154	32213177	6	+	28162770	MOLM13	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	0.22347065387813192	[461]	[389]	1	hSpCas9	negative selection	11556432
32198666	32198689	6	-	28162770	MOLM13	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-3.1320234606425488	[290]	[23]	-8	hSpCas9	negative selection	11556433
32222659	32222682	6	+	28162770	MOLM13	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	-0.1469626910955031	[316]	[206]	-1	hSpCas9	negative selection	11556434
32221208	32221231	6	+	28162770	MOLM13	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	0.3839881239356335	[176]	[166]	3	hSpCas9	negative selection	11556435
32221114	32221137	6	+	28162770	MOLM13	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-1.4463807444295376	[146]	[38]	-6	hSpCas9	negative selection	11556436
32220985	32221008	6	+	28162770	MOLM13	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	-0.6374636186016498	[496]	[230]	-4	hSpCas9	negative selection	11556437
32220135	32220158	6	+	28162770	MOLM13	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.6211754408731023	[561]	[624]	4	hSpCas9	negative selection	11556438
32217035	32217058	6	-	28162770	MOLM13	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	-0.41824265389714227	[206]	[111]	-2	hSpCas9	negative selection	11556439
32216955	32216978	6	+	28162770	MOLM13	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	0.46788938154457893	[289]	[289]	3	hSpCas9	negative selection	11556440
32203776	32203799	6	+	28162770	HEL	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	0.6682739241074945	[279]	[284]	6	hSpCas9	negative selection	11725797
32213154	32213177	6	+	28162770	HEL	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	-0.9250994909295902	[334]	[112]	-5	hSpCas9	negative selection	11725798
32198666	32198689	6	-	28162770	HEL	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-6.517132504778033	[285]	[1]	-9	hSpCas9	negative selection	11725799
32222659	32222682	6	+	28162770	HEL	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	0.13869632666276832	[311]	[219]	1	hSpCas9	negative selection	11725800
32221208	32221231	6	+	28162770	HEL	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	0.842878446489677	[167]	[192]	7	hSpCas9	negative selection	11725801
32221114	32221137	6	+	28162770	HEL	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-1.1985634219805845	[171]	[47]	-6	hSpCas9	negative selection	11725802
32220985	32221008	6	+	28162770	HEL	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	-0.1516770343497491	[443]	[255]	-1	hSpCas9	negative selection	11725803
32220135	32220158	6	+	28162770	HEL	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	-0.43809224261268775	[623]	[294]	-3	hSpCas9	negative selection	11725804
32217035	32217058	6	-	28162770	HEL	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	-0.7320059613304537	[152]	[58]	-5	hSpCas9	negative selection	11725805
32216955	32216978	6	+	28162770	HEL	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	0.49240455891592544	[191]	[172]	4	hSpCas9	negative selection	11725806
32203776	32203799	6	+	28162770	MV411	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	0.18800463726361755	[222]	[213]	1	hSpCas9	negative selection	11895163
32213154	32213177	6	+	28162770	MV411	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	-0.13003653553958522	[277]	[213]	-1	hSpCas9	negative selection	11895164
32198666	32198689	6	-	28162770	MV411	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-3.192185586774342	[216]	[19]	-9	hSpCas9	negative selection	11895165
32222659	32222682	6	+	28162770	MV411	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	1.0328776964119388	[198]	[342]	8	hSpCas9	negative selection	11895166
32221208	32221231	6	+	28162770	MV411	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	-0.17577387994176885	[176]	[131]	-1	hSpCas9	negative selection	11895167
32221114	32221137	6	+	28162770	MV411	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-0.8305649612184977	[94]	[44]	-5	hSpCas9	negative selection	11895168
32220985	32221008	6	+	28162770	MV411	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	-0.8439027607556506	[325]	[152]	-5	hSpCas9	negative selection	11895169
32220135	32220158	6	+	28162770	MV411	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.6069799374699156	[370]	[475]	5	hSpCas9	negative selection	11895170
32217035	32217058	6	-	28162770	MV411	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	0.7388259361917342	[68]	[96]	6	hSpCas9	negative selection	11895171
32216955	32216978	6	+	28162770	MV411	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	0.6696705514658232	[149]	[200]	6	hSpCas9	negative selection	11895172
32203776	32203799	6	+	28162770	MONOMAC1	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	0.8398897219388037	[134]	[276]	7	hSpCas9	negative selection	12064529
32213154	32213177	6	+	28162770	MONOMAC1	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	-0.06670497871187364	[274]	[300]	0	hSpCas9	negative selection	12064530
32198666	32198689	6	-	28162770	MONOMAC1	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-3.7157656493806233	[148]	[12]	-9	hSpCas9	negative selection	12064531
32222659	32222682	6	+	28162770	MONOMAC1	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	-0.18475851728111692	[116]	[117]	-2	hSpCas9	negative selection	12064532
32221208	32221231	6	+	28162770	MONOMAC1	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	0.004597014110096831	[119]	[137]	0	hSpCas9	negative selection	12064533
32221114	32221137	6	+	28162770	MONOMAC1	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	0.5529848999320988	[87]	[147]	5	hSpCas9	negative selection	12064534
32220985	32221008	6	+	28162770	MONOMAC1	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	-0.47907221482340323	[213]	[175]	-4	hSpCas9	negative selection	12064535
32220135	32220158	6	+	28162770	MONOMAC1	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.10645399957113244	[251]	[310]	1	hSpCas9	negative selection	12064536
32217035	32217058	6	-	28162770	MONOMAC1	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	0.3555041759692251	[59]	[87]	3	hSpCas9	negative selection	12064537
32216955	32216978	6	+	28162770	MONOMAC1	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	-1.1132052562560828	[116]	[61]	-7	hSpCas9	negative selection	12064538
32203776	32203799	6	+	28162770	OCIAML2	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	-0.2505813443740124	[43]	[204]	-2	hSpCas9	negative selection	12233895
32213154	32213177	6	+	28162770	OCIAML2	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	-0.5514608998552061	[77]	[294]	-4	hSpCas9	negative selection	12233896
32198666	32198689	6	-	28162770	OCIAML2	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-2.9087509376340464	[41]	[30]	-9	hSpCas9	negative selection	12233897
32222659	32222682	6	+	28162770	OCIAML2	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	0.09470386873006235	[36]	[218]	0	hSpCas9	negative selection	12233898
32221208	32221231	6	+	28162770	OCIAML2	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	-0.9852029980719194	[29]	[83]	-6	hSpCas9	negative selection	12233899
32221114	32221137	6	+	28162770	OCIAML2	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	0.06779008954196475	[20]	[121]	0	hSpCas9	negative selection	12233900
32220985	32221008	6	+	28162770	OCIAML2	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	0.00820432461765186	[46]	[261]	0	hSpCas9	negative selection	12233901
32220135	32220158	6	+	28162770	OCIAML2	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.3706724287387806	[71]	[515]	3	hSpCas9	negative selection	12233902
32217035	32217058	6	-	28162770	OCIAML2	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	0.17047575351652888	[20]	[130]	1	hSpCas9	negative selection	12233903
32216955	32216978	6	+	28162770	OCIAML2	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	0.15555533820550793	[22]	[141]	1	hSpCas9	negative selection	12233904
32203776	32203799	6	+	28162770	OCIAML3	viability	GCAGTGGCAGATGAAACCCAGGG	NOTCH4	ENSG00000204301	-0.24935946893671723	[62]	[159]	-2	hSpCas9	negative selection	12403261
32213154	32213177	6	+	28162770	OCIAML3	viability	GGAGCTTTCCCTCACAGCGCGGG	NOTCH4	ENSG00000204301	-0.1241216640496996	[99]	[276]	-1	hSpCas9	negative selection	12403262
32198666	32198689	6	-	28162770	OCIAML3	viability	GATGTGCTCAGGCCCTGAGGAGG	NOTCH4	ENSG00000204301	-3.6384017596826164	[65]	[15]	-9	hSpCas9	negative selection	12403263
32222659	32222682	6	+	28162770	OCIAML3	viability	GAAGCTGGGTGTCAATGGAGAGG	NOTCH4	ENSG00000204301	0.9857182120308459	[45]	[274]	8	hSpCas9	negative selection	12403264
32221208	32221231	6	+	28162770	OCIAML3	viability	GCATGGCCCTCGAAGCCCGGTGG	NOTCH4	ENSG00000204301	0.06690371363029163	[36]	[116]	0	hSpCas9	negative selection	12403265
32221114	32221137	6	+	28162770	OCIAML3	viability	GAGGCACTGGAAGGAGCCCAGGG	NOTCH4	ENSG00000204301	-1.3012258910963173	[39]	[48]	-7	hSpCas9	negative selection	12403266
32220985	32221008	6	+	28162770	OCIAML3	viability	ACAGAGGCAGAGGTGAAAGGTGG	NOTCH4	ENSG00000204301	0.6818029877985372	[88]	[430]	6	hSpCas9	negative selection	12403267
32220135	32220158	6	+	28162770	OCIAML3	viability	GACACTCGTCCAGGTCCTGGTGG	NOTCH4	ENSG00000204301	0.7305175660492382	[110]	[555]	6	hSpCas9	negative selection	12403268
32217035	32217058	6	-	28162770	OCIAML3	viability	GCCACGCTGTCAAACAGAGGTGG	NOTCH4	ENSG00000204301	1.6263223145553924	[24]	[232]	9	hSpCas9	negative selection	12403269
32216955	32216978	6	+	28162770	OCIAML3	viability	AGAGGGGCAGAGGCAAAAGAAGG	NOTCH4	ENSG00000204301	0.4618455944093544	[37]	[157]	4	hSpCas9	negative selection	12403270