Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 4864
• Symbol: NPC1
• Description: NPC intracellular cholesterol transporter 1

DataSource: http://genomecrispr.dkfz.de/#!/results/NPC1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
23519153	23519176	18	+	26472758	Jiyoye	viability	CGTGCATCATCAGGATACAGAGG	NPC1	ENSG00000141458	0.7782695331971202	[74]	[96]	5	hSpCas9	negative selection	18439
23519117	23519140	18	+	26472758	Jiyoye	viability	AAAGTTTGCCCTGAACGTGGTGG	NPC1	ENSG00000141458	1.0693057427494894	[90]	[143]	7	hSpCas9	negative selection	18440
23520261	23520284	18	-	26472758	Jiyoye	viability	ATCGAGCGGGAAGCACGGGGTGG	NPC1	ENSG00000141458	0.228838140247361	[85]	[75]	1	hSpCas9	negative selection	18441
23524461	23524484	18	+	26472758	Jiyoye	viability	ATCATTATCAGCGCAAGCCAAGG	NPC1	ENSG00000141458	0.6227141318012588	[210]	[244]	4	hSpCas9	negative selection	18442
23507033	23507056	18	+	26472758	Jiyoye	viability	TCAGAGGACCTCAAAGACTGTGG	NPC1	ENSG00000141458	1.0860557456146687	[222]	[356]	7	hSpCas9	negative selection	18443
23518932	23518955	18	+	26472758	Jiyoye	viability	GACCTCCAACAGCACAGGAGCGG	NPC1	ENSG00000141458	-0.53837683447175	[207]	[107]	-4	hSpCas9	negative selection	18444
23530111	23530134	18	-	26472758	Jiyoye	viability	CCAAAGGTTTGGAGTCGCTGAGG	NPC1	ENSG00000141458	1.2389038989160748	[108]	[193]	7	hSpCas9	negative selection	18445
23530571	23530594	18	+	26472758	Jiyoye	viability	AGCGAAACCAGCGTTTGCGAGGG	NPC1	ENSG00000141458	3.214530303563477	[0]	[6]	9	hSpCas9	negative selection	18446
23539874	23539897	18	-	26472758	Jiyoye	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	0.32290646460826933	[140]	[132]	2	hSpCas9	negative selection	110526
23538563	23538586	18	+	26472758	Jiyoye	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	-1.8280410801881581	[112]	[23]	-8	hSpCas9	negative selection	110527
23586301	23586324	18	+	26472758	Jiyoye	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-0.7532892906873727	[37]	[16]	-5	hSpCas9	negative selection	110528
23560460	23560483	18	-	26472758	Jiyoye	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	-0.1378207118976379	[266]	[182]	-1	hSpCas9	negative selection	110529
23556277	23556300	18	+	26472758	Jiyoye	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.39206848911566494	[95]	[94]	3	hSpCas9	negative selection	110530
23556250	23556273	18	+	26472758	Jiyoye	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	0.17522865345617666	[201]	[171]	1	hSpCas9	negative selection	110531
23548068	23548091	18	+	26472758	Jiyoye	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	-0.34771212065759516	[107]	[63]	-2	hSpCas9	negative selection	110532
23548026	23548049	18	-	26472758	Jiyoye	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	-0.9844031449489814	[243]	[92]	-6	hSpCas9	negative selection	110533
23544440	23544463	18	+	26472758	Jiyoye	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.8657145194213038	[146]	[201]	6	hSpCas9	negative selection	110534
23538607	23538630	18	-	26472758	Jiyoye	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	-0.14383978729194513	[188]	[128]	-1	hSpCas9	negative selection	110535
23519153	23519176	18	+	26472758	KBM7	viability	CGTGCATCATCAGGATACAGAGG	NPC1	ENSG00000141458	1.031643177518602	[402,552]	[495,444]	9	hSpCas9	negative selection	209557
23519117	23519140	18	+	26472758	KBM7	viability	AAAGTTTGCCCTGAACGTGGTGG	NPC1	ENSG00000141458	0.40413602358568734	[782,635]	[515,369]	4	hSpCas9	negative selection	209558
23520261	23520284	18	-	26472758	KBM7	viability	ATCGAGCGGGAAGCACGGGGTGG	NPC1	ENSG00000141458	1.3341350202461186	[287,148]	[348,164]	9	hSpCas9	negative selection	209559
23524461	23524484	18	+	26472758	KBM7	viability	ATCATTATCAGCGCAAGCCAAGG	NPC1	ENSG00000141458	0.6395715707798517	[866,885]	[808,499]	7	hSpCas9	negative selection	209560
23507033	23507056	18	+	26472758	KBM7	viability	TCAGAGGACCTCAAAGACTGTGG	NPC1	ENSG00000141458	0.6572498152470965	[924,905]	[927,460]	7	hSpCas9	negative selection	209561
23518932	23518955	18	+	26472758	KBM7	viability	GACCTCCAACAGCACAGGAGCGG	NPC1	ENSG00000141458	0.9192601278803574	[540,542]	[599,380]	8	hSpCas9	negative selection	209562
23530111	23530134	18	-	26472758	KBM7	viability	CCAAAGGTTTGGAGTCGCTGAGG	NPC1	ENSG00000141458	1.4649484887882476	[617,359]	[777,479]	9	hSpCas9	negative selection	209563
23530571	23530594	18	+	26472758	KBM7	viability	AGCGAAACCAGCGTTTGCGAGGG	NPC1	ENSG00000141458	1.865933081491438	[45,4]	[71,11]	9	hSpCas9	negative selection	209564
23539874	23539897	18	-	26472758	KBM7	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	-0.34160588017019944	[795,639]	[259,268]	-3	hSpCas9	negative selection	301644
23538563	23538586	18	+	26472758	KBM7	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	-0.49626041947672306	[235,187]	[75,64]	-4	hSpCas9	negative selection	301645
23586301	23586324	18	+	26472758	KBM7	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-1.1857065993767775	[203,189]	[63,19]	-7	hSpCas9	negative selection	301646
23560460	23560483	18	-	26472758	KBM7	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	0.06939657496474216	[1170,682]	[517,383]	0	hSpCas9	negative selection	301647
23556277	23556300	18	+	26472758	KBM7	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-0.27329112442432596	[613,303]	[186,160]	-3	hSpCas9	negative selection	301648
23556250	23556273	18	+	26472758	KBM7	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	0.23489289000070668	[814,632]	[351,437]	2	hSpCas9	negative selection	301649
23548068	23548091	18	+	26472758	KBM7	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	0.6762271203573382	[256,286]	[177,231]	7	hSpCas9	negative selection	301650
23548026	23548049	18	-	26472758	KBM7	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	0.221064857149887	[710,577]	[318,379]	2	hSpCas9	negative selection	301651
23544440	23544463	18	+	26472758	KBM7	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.34479953840899447	[820,642]	[333,522]	3	hSpCas9	negative selection	301652
23538607	23538630	18	-	26472758	KBM7	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	-0.16913260439265793	[652,409]	[205,228]	-2	hSpCas9	negative selection	301653
23519153	23519176	18	+	26472758	Raji	viability	CGTGCATCATCAGGATACAGAGG	NPC1	ENSG00000141458	0.7594602319532927	[223]	[87]	7	hSpCas9	negative selection	400675
23519117	23519140	18	+	26472758	Raji	viability	AAAGTTTGCCCTGAACGTGGTGG	NPC1	ENSG00000141458	1.0790017340037772	[307]	[150]	8	hSpCas9	negative selection	400676
23520261	23520284	18	-	26472758	Raji	viability	ATCGAGCGGGAAGCACGGGGTGG	NPC1	ENSG00000141458	0.9191798002129783	[138]	[60]	8	hSpCas9	negative selection	400677
23524461	23524484	18	+	26472758	Raji	viability	ATCATTATCAGCGCAAGCCAAGG	NPC1	ENSG00000141458	0.6849740474384033	[326]	[121]	6	hSpCas9	negative selection	400678
23507033	23507056	18	+	26472758	Raji	viability	TCAGAGGACCTCAAAGACTGTGG	NPC1	ENSG00000141458	0.8542288602664643	[552]	[231]	7	hSpCas9	negative selection	400679
23518932	23518955	18	+	26472758	Raji	viability	GACCTCCAACAGCACAGGAGCGG	NPC1	ENSG00000141458	1.1186988486014335	[253]	[127]	8	hSpCas9	negative selection	400680
23530111	23530134	18	-	26472758	Raji	viability	CCAAAGGTTTGGAGTCGCTGAGG	NPC1	ENSG00000141458	0.9773940652809711	[382]	[174]	8	hSpCas9	negative selection	400681
23530571	23530594	18	+	26472758	Raji	viability	AGCGAAACCAGCGTTTGCGAGGG	NPC1	ENSG00000141458	-0.6999713866840049	[20]	[2]	-5	hSpCas9	negative selection	400682
23539874	23539897	18	-	26472758	Raji	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	-0.29032714617537936	[468]	[88]	-2	hSpCas9	negative selection	492762
23538563	23538586	18	+	26472758	Raji	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	-0.7505974597539726	[86]	[11]	-5	hSpCas9	negative selection	492763
23586301	23586324	18	+	26472758	Raji	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	1.0004683314570875	[55]	[25]	8	hSpCas9	negative selection	492764
23560460	23560483	18	-	26472758	Raji	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	0.37041794120739346	[459]	[137]	3	hSpCas9	negative selection	492765
23556277	23556300	18	+	26472758	Raji	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-0.25689085022335767	[241]	[46]	-2	hSpCas9	negative selection	492766
23556250	23556273	18	+	26472758	Raji	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	0.7923970499050841	[310]	[124]	7	hSpCas9	negative selection	492767
23548068	23548091	18	+	26472758	Raji	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	-1.4472053163040377	[140]	[11]	-7	hSpCas9	negative selection	492768
23548026	23548049	18	-	26472758	Raji	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	-0.20136917076602956	[435]	[87]	-2	hSpCas9	negative selection	492769
23544440	23544463	18	+	26472758	Raji	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	-0.2645852420133585	[351]	[67]	-2	hSpCas9	negative selection	492770
23538607	23538630	18	-	26472758	Raji	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	0.5676502886454411	[313]	[107]	5	hSpCas9	negative selection	492771
23519153	23519176	18	+	26472758	K562	viability	CGTGCATCATCAGGATACAGAGG	NPC1	ENSG00000141458	1.2339567888478222	[345]	[686]	9	hSpCas9	negative selection	591793
23519117	23519140	18	+	26472758	K562	viability	AAAGTTTGCCCTGAACGTGGTGG	NPC1	ENSG00000141458	0.7617636497462588	[363]	[520]	6	hSpCas9	negative selection	591794
23520261	23520284	18	-	26472758	K562	viability	ATCGAGCGGGAAGCACGGGGTGG	NPC1	ENSG00000141458	0.6557711801374347	[293]	[390]	5	hSpCas9	negative selection	591795
23524461	23524484	18	+	26472758	K562	viability	ATCATTATCAGCGCAAGCCAAGG	NPC1	ENSG00000141458	0.5041780014673796	[587]	[703]	4	hSpCas9	negative selection	591796
23507033	23507056	18	+	26472758	K562	viability	TCAGAGGACCTCAAAGACTGTGG	NPC1	ENSG00000141458	1.1248633429711645	[678]	[1249]	8	hSpCas9	negative selection	591797
23518932	23518955	18	+	26472758	K562	viability	GACCTCCAACAGCACAGGAGCGG	NPC1	ENSG00000141458	0.7135814408062586	[496]	[687]	6	hSpCas9	negative selection	591798
23530111	23530134	18	-	26472758	K562	viability	CCAAAGGTTTGGAGTCGCTGAGG	NPC1	ENSG00000141458	0.8682702417811978	[304]	[469]	7	hSpCas9	negative selection	591799
23530571	23530594	18	+	26472758	K562	viability	AGCGAAACCAGCGTTTGCGAGGG	NPC1	ENSG00000141458	-3.3405437730547094	[23]	[1]	-8	hSpCas9	negative selection	591800
23539874	23539897	18	-	26472758	K562	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	-0.571956199715278	[721]	[409]	-4	hSpCas9	negative selection	683880
23538563	23538586	18	+	26472758	K562	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	-0.9562786225706823	[153]	[66]	-5	hSpCas9	negative selection	683881
23586301	23586324	18	+	26472758	K562	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-3.834532613728375	[168]	[9]	-9	hSpCas9	negative selection	683882
23560460	23560483	18	-	26472758	K562	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	0.6002771665049962	[789]	[1010]	5	hSpCas9	negative selection	683883
23556277	23556300	18	+	26472758	K562	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.6579588785587884	[240]	[320]	5	hSpCas9	negative selection	683884
23556250	23556273	18	+	26472758	K562	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	-0.4503503028455517	[729]	[450]	-3	hSpCas9	negative selection	683885
23548068	23548091	18	+	26472758	K562	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	-0.24461935305617377	[159]	[113]	-2	hSpCas9	negative selection	683886
23548026	23548049	18	-	26472758	K562	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	0.6406195849324351	[635]	[836]	5	hSpCas9	negative selection	683887
23544440	23544463	18	+	26472758	K562	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.3005238295515972	[579]	[602]	2	hSpCas9	negative selection	683888
23538607	23538630	18	-	26472758	K562	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	0.6135257237214933	[366]	[473]	5	hSpCas9	negative selection	683889
23551665	23551688	18	+	26627737	DLD1	viability	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	0.5117490095759392	[1416]	[473,598,794]	5	hSpCas9	negative selection	801201
23554880	23554903	18	+	26627737	DLD1	viability	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	1.0098938847980947	[791]	[457,595,452]	8	hSpCas9	negative selection	801202
23556277	23556300	18	+	26627737	DLD1	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.6050836313665318	[108]	[13,89,52]	6	hSpCas9	negative selection	801203
23560324	23560347	18	+	26627737	DLD1	viability	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.4528870296175542	[219]	[23,77,49]	-4	hSpCas9	negative selection	801204
23561454	23561477	18	+	26627737	DLD1	viability	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-0.005214380883331982	[355]	[101,177,62]	0	hSpCas9	negative selection	801205
23586289	23586312	18	+	26627737	DLD1	viability	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	1.6776585309281176	[0]	[0,0,0]	9	hSpCas9	negative selection	801206
23551665	23551688	18	+	26627737	GBM cells	viability after 5 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	0.5028028789484793	[832]	[713,551]	7	hSpCas9	negative selection	883516
23554880	23554903	18	+	26627737	GBM cells	viability after 5 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	0.11994075419790384	[452]	[251,275]	2	hSpCas9	negative selection	883517
23556277	23556300	18	+	26627737	GBM cells	viability after 5 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.16194828071947942	[79]	[46,48]	2	hSpCas9	negative selection	883518
23560324	23560347	18	+	26627737	GBM cells	viability after 5 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	0.28509651149234405	[100]	[58,72]	4	hSpCas9	negative selection	883519
23561454	23561477	18	+	26627737	GBM cells	viability after 5 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-0.9941709211978027	[207]	[58,52]	-9	hSpCas9	negative selection	883520
23586289	23586312	18	+	26627737	GBM cells	viability after 5 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	0.8989138748856851	[0]	[0,0]	9	hSpCas9	negative selection	883521
23551665	23551688	18	+	26627737	GBM cells	viability after 13 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	0.17611312382697308	[832]	[567,463]	2	hSpCas9	negative selection	965831
23554880	23554903	18	+	26627737	GBM cells	viability after 13 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	0.15424926051859944	[452]	[358,203]	2	hSpCas9	negative selection	965832
23556277	23556300	18	+	26627737	GBM cells	viability after 13 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-0.08434431671052578	[79]	[62,22]	-1	hSpCas9	negative selection	965833
23560324	23560347	18	+	26627737	GBM cells	viability after 13 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	0.44931175486066854	[100]	[65,81]	5	hSpCas9	negative selection	965834
23561454	23561477	18	+	26627737	GBM cells	viability after 13 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-0.45060066629788537	[207]	[145,30]	-5	hSpCas9	negative selection	965835
23586289	23586312	18	+	26627737	GBM cells	viability after 13 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	0.8821031235784469	[0]	[0,0]	9	hSpCas9	negative selection	965836
23551665	23551688	18	+	26627737	GBM cells	viability after 21 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	-0.1317861689799349	[832]	[411,413]	-1	hSpCas9	negative selection	1048146
23554880	23554903	18	+	26627737	GBM cells	viability after 21 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	0.14774300794049577	[452]	[280,264]	1	hSpCas9	negative selection	1048147
23556277	23556300	18	+	26627737	GBM cells	viability after 21 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.6111751061540946	[79]	[68,63]	6	hSpCas9	negative selection	1048148
23560324	23560347	18	+	26627737	GBM cells	viability after 21 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.37956700244470176	[100]	[37,45]	-3	hSpCas9	negative selection	1048149
23561454	23561477	18	+	26627737	GBM cells	viability after 21 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-0.05954190709282031	[207]	[109,106]	0	hSpCas9	negative selection	1048150
23586289	23586312	18	+	26627737	GBM cells	viability after 21 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	0.8802332996156581	[0]	[0,0]	8	hSpCas9	negative selection	1048151
23551665	23551688	18	+	26627737	RPE1	viability after 9 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	0.5736576659855328	[3221]	[1285,1778]	4	hSpCas9	negative selection	1130461
23554880	23554903	18	+	26627737	RPE1	viability after 9 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	0.15847542460829334	[1740]	[434,831]	1	hSpCas9	negative selection	1130462
23556277	23556300	18	+	26627737	RPE1	viability after 9 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-4.028182718558197	[286]	[8,0]	-9	hSpCas9	negative selection	1130463
23560324	23560347	18	+	26627737	RPE1	viability after 9 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.7901316094522238	[486]	[109,59]	-5	hSpCas9	negative selection	1130464
23561454	23561477	18	+	26627737	RPE1	viability after 9 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-0.37055021487358575	[600]	[162,122]	-3	hSpCas9	negative selection	1130465
23586289	23586312	18	+	26627737	RPE1	viability after 9 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	1.6754465303148196	[0]	[0,0]	8	hSpCas9	negative selection	1130466
23551665	23551688	18	+	26627737	RPE1	viability after 12 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	1.1136378555611715	[3221]	[1844,1902]	6	hSpCas9	negative selection	1212776
23554880	23554903	18	+	26627737	RPE1	viability after 12 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	0.5944023022470042	[1740]	[577,841]	4	hSpCas9	negative selection	1212777
23556277	23556300	18	+	26627737	RPE1	viability after 12 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-2.2107264587470197	[286]	[4,28]	-8	hSpCas9	negative selection	1212778
23560324	23560347	18	+	26627737	RPE1	viability after 12 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.9472377692484985	[486]	[96,36]	-6	hSpCas9	negative selection	1212779
23561454	23561477	18	+	26627737	RPE1	viability after 12 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-0.17610344380204412	[600]	[173,109]	-1	hSpCas9	negative selection	1212780
23586289	23586312	18	+	26627737	RPE1	viability after 12 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	1.8961114116731377	[0]	[0,0]	8	hSpCas9	negative selection	1212781
23551665	23551688	18	+	26627737	RPE1	viability after 15 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	0.9156505114971893	[3221]	[1699,1737]	5	hSpCas9	negative selection	1295091
23554880	23554903	18	+	26627737	RPE1	viability after 15 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	0.6066123751318668	[1740]	[698,798]	4	hSpCas9	negative selection	1295092
23556277	23556300	18	+	26627737	RPE1	viability after 15 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-5.749517661010639	[286]	[0,1]	-9	hSpCas9	negative selection	1295093
23560324	23560347	18	+	26627737	RPE1	viability after 15 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.42476682267664445	[486]	[207,0]	-3	hSpCas9	negative selection	1295094
23561454	23561477	18	+	26627737	RPE1	viability after 15 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	0.28634645776005013	[600]	[300,116]	1	hSpCas9	negative selection	1295095
23586289	23586312	18	+	26627737	RPE1	viability after 15 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	1.8217488738718943	[0]	[0,0]	8	hSpCas9	negative selection	1295096
23551665	23551688	18	+	26627737	RPE1	viability after 18 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	1.306410922450345	[3221]	[2005,2304]	7	hSpCas9	negative selection	1377406
23554880	23554903	18	+	26627737	RPE1	viability after 18 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	0.886519063719738	[1740]	[652,1098]	5	hSpCas9	negative selection	1377407
23556277	23556300	18	+	26627737	RPE1	viability after 18 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-3.5095028337190803	[286]	[0,12]	-9	hSpCas9	negative selection	1377408
23560324	23560347	18	+	26627737	RPE1	viability after 18 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.34089506134877146	[486]	[198,1]	-2	hSpCas9	negative selection	1377409
23561454	23561477	18	+	26627737	RPE1	viability after 18 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	0.37695155047838524	[600]	[286,128]	2	hSpCas9	negative selection	1377410
23586289	23586312	18	+	26627737	RPE1	viability after 18 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	1.889668260100743	[0]	[0,0]	8	hSpCas9	negative selection	1377411
23551665	23551688	18	+	26627737	HeLa	viability after 8 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	0.5769214909215199	[1149]	[1046,697,572]	5	hSpCas9	negative selection	1459721
23554880	23554903	18	+	26627737	HeLa	viability after 8 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	-0.6655277088675386	[1039]	[366,311,200]	-6	hSpCas9	negative selection	1459722
23556277	23556300	18	+	26627737	HeLa	viability after 8 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-0.8942135776105274	[229]	[60,90,13]	-7	hSpCas9	negative selection	1459723
23560324	23560347	18	+	26627737	HeLa	viability after 8 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.981066884795452	[317]	[121,92,10]	-7	hSpCas9	negative selection	1459724
23561454	23561477	18	+	26627737	HeLa	viability after 8 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-1.75154168696264	[450]	[136,23,32]	-9	hSpCas9	negative selection	1459725
23586289	23586312	18	+	26627737	HeLa	viability after 8 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	1.200473099817617	[0]	[0,0,0]	8	hSpCas9	negative selection	1459726
23551665	23551688	18	+	26627737	HeLa	viability after 12 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	0.5116342396055331	[1149]	[1064,657,322]	4	hSpCas9	negative selection	1542036
23554880	23554903	18	+	26627737	HeLa	viability after 12 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	-0.6314445533599841	[1039]	[275,317,233]	-5	hSpCas9	negative selection	1542037
23556277	23556300	18	+	26627737	HeLa	viability after 12 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-0.6643080128063198	[229]	[64,88,22]	-5	hSpCas9	negative selection	1542038
23560324	23560347	18	+	26627737	HeLa	viability after 12 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-1.3047032688718796	[317]	[10,84,58]	-8	hSpCas9	negative selection	1542039
23561454	23561477	18	+	26627737	HeLa	viability after 12 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-0.49752309470179146	[450]	[270,47,89]	-4	hSpCas9	negative selection	1542040
23586289	23586312	18	+	26627737	HeLa	viability after 12 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	1.2748581272013126	[0]	[0,0,0]	8	hSpCas9	negative selection	1542041
23551665	23551688	18	+	26627737	HeLa	viability after 15 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	0.7464867087329603	[1149]	[787,1160,375]	6	hSpCas9	negative selection	1624351
23554880	23554903	18	+	26627737	HeLa	viability after 15 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	-0.5508932115733225	[1039]	[167,345,359]	-5	hSpCas9	negative selection	1624352
23556277	23556300	18	+	26627737	HeLa	viability after 15 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-0.9842635806111654	[229]	[30,17,96]	-7	hSpCas9	negative selection	1624353
23560324	23560347	18	+	26627737	HeLa	viability after 15 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.5960248312083999	[317]	[52,110,93]	-5	hSpCas9	negative selection	1624354
23561454	23561477	18	+	26627737	HeLa	viability after 15 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-1.456082184450147	[450]	[46,38,118]	-8	hSpCas9	negative selection	1624355
23586289	23586312	18	+	26627737	HeLa	viability after 15 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	1.2965331123080048	[0]	[0,0,0]	8	hSpCas9	negative selection	1624356
23551665	23551688	18	+	26627737	HeLa	viability after 18 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	0.7438472414467512	[1149]	[534,949,375]	6	hSpCas9	negative selection	1706666
23554880	23554903	18	+	26627737	HeLa	viability after 18 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	-0.5666855623143309	[1039]	[102,290,359]	-5	hSpCas9	negative selection	1706667
23556277	23556300	18	+	26627737	HeLa	viability after 18 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-1.0243610817028537	[229]	[18,13,96]	-7	hSpCas9	negative selection	1706668
23560324	23560347	18	+	26627737	HeLa	viability after 18 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.5830069567427506	[317]	[36,91,93]	-5	hSpCas9	negative selection	1706669
23561454	23561477	18	+	26627737	HeLa	viability after 18 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-1.453533963317538	[450]	[27,36,118]	-8	hSpCas9	negative selection	1706670
23586289	23586312	18	+	26627737	HeLa	viability after 18 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	1.6067387639618715	[0]	[0,0,0]	9	hSpCas9	negative selection	1706671
23551665	23551688	18	+	26627737	HCT116	viability after 6 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	1.3628841668209852	[1953]	[218,1104]	7	hSpCas9	negative selection	1788981
23554880	23554903	18	+	26627737	HCT116	viability after 6 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	-0.3321453761030204	[1313]	[156,167]	-2	hSpCas9	negative selection	1788982
23556277	23556300	18	+	26627737	HCT116	viability after 6 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.7282611529603338	[124]	[38,28]	4	hSpCas9	negative selection	1788983
23560324	23560347	18	+	26627737	HCT116	viability after 6 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.17335880038103757	[199]	[72,2]	-1	hSpCas9	negative selection	1788984
23561454	23561477	18	+	26627737	HCT116	viability after 6 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	0.6429605307437034	[482]	[37,162]	3	hSpCas9	negative selection	1788985
23586289	23586312	18	+	26627737	HCT116	viability after 6 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	2.6692602571875668	[0]	[0,0]	9	hSpCas9	negative selection	1788986
23551665	23551688	18	+	26627737	HCT116	viability after 8 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	0.17296801622882763	[1057]	[712,624,634]	2	hSpCas9	negative selection	1871296
23554880	23554903	18	+	26627737	HCT116	viability after 8 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	0.1735003928499439	[666]	[426,341,473]	2	hSpCas9	negative selection	1871297
23556277	23556300	18	+	26627737	HCT116	viability after 8 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-0.2510130028329316	[102]	[33,74,33]	-3	hSpCas9	negative selection	1871298
23560324	23560347	18	+	26627737	HCT116	viability after 8 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	0.7914347569911008	[91]	[97,43,120]	7	hSpCas9	negative selection	1871299
23561454	23561477	18	+	26627737	HCT116	viability after 8 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	2.0598809537754503	[48]	[91,184,60]	9	hSpCas9	negative selection	1871300
23586289	23586312	18	+	26627737	HCT116	viability after 8 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	0.8598070938499998	[0]	[0,0,0]	7	hSpCas9	negative selection	1871301
23551665	23551688	18	+	26627737	HCT116	viability after 9 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	0.4638155986440591	[1953]	[670,757]	3	hSpCas9	negative selection	1953611
23554880	23554903	18	+	26627737	HCT116	viability after 9 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	-0.9908304189998235	[1313]	[280,93]	-6	hSpCas9	negative selection	1953612
23556277	23556300	18	+	26627737	HCT116	viability after 9 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.058800988882529825	[124]	[36,32]	0	hSpCas9	negative selection	1953613
23560324	23560347	18	+	26627737	HCT116	viability after 9 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	0.37022306565251784	[199]	[63,72]	2	hSpCas9	negative selection	1953614
23561454	23561477	18	+	26627737	HCT116	viability after 9 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	1.0275351450335823	[482]	[382,167]	7	hSpCas9	negative selection	1953615
23586289	23586312	18	+	26627737	HCT116	viability after 9 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	1.9049898113534676	[0]	[0,0]	9	hSpCas9	negative selection	1953616
23551665	23551688	18	+	26627737	HCT116	viability after 12 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	-0.1084082300911402	[1057]	[709,506,312]	-1	hSpCas9	negative selection	2035926
23554880	23554903	18	+	26627737	HCT116	viability after 12 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	0.26556068293800017	[666]	[382,442,441]	2	hSpCas9	negative selection	2035927
23556277	23556300	18	+	26627737	HCT116	viability after 12 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.21455330402502515	[102]	[30,94,65]	2	hSpCas9	negative selection	2035928
23560324	23560347	18	+	26627737	HCT116	viability after 12 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	0.6308040295560664	[91]	[34,70,121]	6	hSpCas9	negative selection	2035929
23561454	23561477	18	+	26627737	HCT116	viability after 12 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	2.2292527406317078	[48]	[96,148,118]	9	hSpCas9	negative selection	2035930
23586289	23586312	18	+	26627737	HCT116	viability after 12 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	0.9281650954308303	[0]	[0,0,0]	7	hSpCas9	negative selection	2035931
23551665	23551688	18	+	26627737	HCT116	viability after 15 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	0.03955311910565684	[1057]	[940,429,541]	0	hSpCas9	negative selection	2118241
23554880	23554903	18	+	26627737	HCT116	viability after 15 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	0.07478785917707187	[666]	[459,337,418]	0	hSpCas9	negative selection	2118242
23556277	23556300	18	+	26627737	HCT116	viability after 15 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.5364753805803617	[102]	[116,42,100]	5	hSpCas9	negative selection	2118243
23560324	23560347	18	+	26627737	HCT116	viability after 15 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	0.4189964807650086	[91]	[59,110,39]	4	hSpCas9	negative selection	2118244
23561454	23561477	18	+	26627737	HCT116	viability after 15 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	2.3677208392784364	[48]	[279,99,72]	9	hSpCas9	negative selection	2118245
23586289	23586312	18	+	26627737	HCT116	viability after 15 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	0.8001368291432343	[0]	[0,0,0]	7	hSpCas9	negative selection	2118246
23551665	23551688	18	+	26627737	HCT116	viability after 18 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	0.38678024111241105	[1057]	[790,543,679]	3	hSpCas9	negative selection	2200556
23554880	23554903	18	+	26627737	HCT116	viability after 18 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	0.3720434709790186	[666]	[412,358,486]	3	hSpCas9	negative selection	2200557
23556277	23556300	18	+	26627737	HCT116	viability after 18 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-0.19003822003977922	[102]	[54,29,46]	-2	hSpCas9	negative selection	2200558
23560324	23560347	18	+	26627737	HCT116	viability after 18 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	1.045222531724785	[91]	[77,91,105]	7	hSpCas9	negative selection	2200559
23561454	23561477	18	+	26627737	HCT116	viability after 18 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	2.447020192914512	[48]	[145,160,75]	9	hSpCas9	negative selection	2200560
23586289	23586312	18	+	26627737	HCT116	viability after 18 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	1.0485523756554223	[0]	[0,0,0]	7	hSpCas9	negative selection	2200561
23573537	23573560	18	-	24336569	HL60	viability	TGTGTTTGGTATGGAGAGTGTGG	NPC1	ENSG00000141458	-0.18862759557792708	[893]	[1659]	-2	hSpCas9	negative selection	2280935
23573546	23573569	18	-	24336569	HL60	viability	TCACAGTCCTGTGTTTGGTATGG	NPC1	ENSG00000141458	-0.22364137962785346	[942]	[1708]	-2	hSpCas9	negative selection	2280936
23586273	23586296	18	+	24336569	HL60	viability	CGGCGACCGCTCACCTGCGCTGG	NPC1	ENSG00000141458	-0.40440189697416895	[535]	[856]	-4	hSpCas9	negative selection	2280937
23586286	23586309	18	-	24336569	HL60	viability	GCTGCTACTGTGTCCAGCGCAGG	NPC1	ENSG00000141458	-0.9893458986404648	[90]	[96]	-7	hSpCas9	negative selection	2280938
23586292	23586315	18	+	24336569	HL60	viability	CTGGACACAGTAGCAGCAGGAGG	NPC1	ENSG00000141458	0.34592450176648576	[566]	[1524]	3	hSpCas9	negative selection	2280939
23586301	23586324	18	+	24336569	HL60	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-0.8126061523525292	[1400]	[1687]	-6	hSpCas9	negative selection	2280940
23586307	23586330	18	+	24336569	HL60	viability	GCAGGAGGAGGCCAAGGGCCAGG	NPC1	ENSG00000141458	-0.4245380043878074	[944]	[1489]	-4	hSpCas9	negative selection	2280941
23586317	23586340	18	+	24336569	HL60	viability	GCCAAGGGCCAGGCCGCGAGCGG	NPC1	ENSG00000141458	0.6091085880528586	[631]	[2039]	5	hSpCas9	negative selection	2280942
23586325	23586348	18	-	24336569	HL60	viability	CAGCATGACCGCTCGCGGCCTGG	NPC1	ENSG00000141458	-0.6694104597888739	[362]	[482]	-6	hSpCas9	negative selection	2280943
23586330	23586353	18	-	24336569	HL60	viability	GGCCACAGCATGACCGCTCGCGG	NPC1	ENSG00000141458	0.7386802618788422	[368]	[1302]	6	hSpCas9	negative selection	2280944
23573537	23573560	18	-	24336569	KBM7	viability	TGTGTTTGGTATGGAGAGTGTGG	NPC1	ENSG00000141458	0.5213493575181115	[703]	[2755]	5	hSpCas9	negative selection	2348112
23573546	23573569	18	-	24336569	KBM7	viability	TCACAGTCCTGTGTTTGGTATGG	NPC1	ENSG00000141458	-0.18876547365105467	[541]	[1296]	-2	hSpCas9	negative selection	2348113
23586273	23586296	18	+	24336569	KBM7	viability	CGGCGACCGCTCACCTGCGCTGG	NPC1	ENSG00000141458	0.12222349700126789	[286]	[851]	1	hSpCas9	negative selection	2348114
23586286	23586309	18	-	24336569	KBM7	viability	GCTGCTACTGTGTCCAGCGCAGG	NPC1	ENSG00000141458	-1.1327058591954708	[122]	[152]	-7	hSpCas9	negative selection	2348115
23586292	23586315	18	+	24336569	KBM7	viability	CTGGACACAGTAGCAGCAGGAGG	NPC1	ENSG00000141458	-0.03870268189671283	[527]	[1401]	0	hSpCas9	negative selection	2348116
23586301	23586324	18	+	24336569	KBM7	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-2.3008080038182577	[662]	[366]	-8	hSpCas9	negative selection	2348117
23586307	23586330	18	+	24336569	KBM7	viability	GCAGGAGGAGGCCAAGGGCCAGG	NPC1	ENSG00000141458	0.2120681137725275	[526]	[1664]	2	hSpCas9	negative selection	2348118
23586317	23586340	18	+	24336569	KBM7	viability	GCCAAGGGCCAGGCCGCGAGCGG	NPC1	ENSG00000141458	-0.8745398632035458	[647]	[963]	-6	hSpCas9	negative selection	2348119
23586325	23586348	18	-	24336569	KBM7	viability	CAGCATGACCGCTCGCGGCCTGG	NPC1	ENSG00000141458	1.1600211078520053	[136]	[834]	8	hSpCas9	negative selection	2348120
23586330	23586353	18	-	24336569	KBM7	viability	GGCCACAGCATGACCGCTCGCGG	NPC1	ENSG00000141458	0.05727656497843034	[431]	[1225]	0	hSpCas9	negative selection	2348121
23586767	23586790	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCGAAGGGTAGTGCTGTTCTGG	NPC1	ENSG00000141458	-1.0893537850186092	[110,513]	[41,21]	-6	dCas9-VP64	positive selection	2383549
23586794	23586817	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTCCGGGTAAGGTCCCGCCCGG	NPC1	ENSG00000141458	-1.8278009597444271	[28,229]	[2,12]	-8	dCas9-VP64	positive selection	2383550
23586692	23586715	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTTGTGCCAACGGTTTCTGG	NPC1	ENSG00000141458	1.0616345503534974	[60,6]	[23,5]	4	dCas9-VP64	positive selection	2383551
23571609	23571632	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATGCCACTGTACTCCAGCCTCGG	NPC1	ENSG00000141458	-1.9834711090057278	[190,159]	[9,8]	-9	dCas9-VP64	positive selection	2385615
23512133	23512156	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTCAGCCTCCCAAGTAGCTGG	NPC1	ENSG00000141458	0.6911400425855385	[25,30]	[5,13]	3	dCas9-VP64	positive selection	2396580
23517932	23517955	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTCTTGAACTCCTGGGCTCGGG	NPC1	ENSG00000141458	4.2770735618878515	[141,50]	[775,15]	9	dCas9-VP64	positive selection	2397425
23586767	23586790	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCGAAGGGTAGTGCTGTTCTGG	NPC1	ENSG00000141458	0.31427817211932474	[82,30]	[39,6]	2	dCas9-VP64	positive selection	2478804
23586794	23586817	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTCCGGGTAAGGTCCCGCCCGG	NPC1	ENSG00000141458	3.0595014394508713	[36,60]	[10,249]	9	dCas9-VP64	positive selection	2478805
23586692	23586715	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTTGTGCCAACGGTTTCTGG	NPC1	ENSG00000141458	0.61783081525595	[73,39]	[9,44]	4	dCas9-VP64	positive selection	2478806
23571609	23571632	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATGCCACTGTACTCCAGCCTCGG	NPC1	ENSG00000141458	-0.49457347436203747	[225,196]	[51,45]	-5	dCas9-VP64	positive selection	2480870
23512133	23512156	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTCAGCCTCCCAAGTAGCTGG	NPC1	ENSG00000141458	0.4030393266100577	[90,274]	[19,131]	3	dCas9-VP64	positive selection	2491835
23517932	23517955	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTCTTGAACTCCTGGGCTCGGG	NPC1	ENSG00000141458	0.8672449668792414	[148,204]	[104,104]	6	dCas9-VP64	positive selection	2492680
23573546	23573569	18	-	27260157	DLD1	viability	TCACAGTCCTGTGTTTGGTATGG	NPC1	ENSG00000141458	-0.815630098352442	[]	[]	-6	hSpCas9	negative selection	2574596
23586292	23586315	18	+	27260157	DLD1	viability	CTGGACACAGTAGCAGCAGGAGG	NPC1	ENSG00000141458	0.186030001341355	[]	[]	3	hSpCas9	negative selection	2577219
23560412	23560435	18	-	27260157	DLD1	viability	CTGTGACGAGTCTGTGGATGAGG	NPC1	ENSG00000141458	0.60376549273877	[]	[]	8	hSpCas9	negative selection	2578398
23586273	23586296	18	+	27260157	DLD1	viability	CGGCGACCGCTCACCTGCGCTGG	NPC1	ENSG00000141458	-0.365808389654204	[]	[]	-3	hSpCas9	negative selection	2580485
23586301	23586324	18	+	27260157	DLD1	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-0.812103293558422	[]	[]	-6	hSpCas9	negative selection	2582785
23560316	23560339	18	-	27260157	DLD1	viability	TCCCTGGACGATCCTTGGCTTGG	NPC1	ENSG00000141458	-0.112477013278598	[]	[]	-1	hSpCas9	negative selection	2584268
23560304	23560327	18	+	27260157	DLD1	viability	CATACATGGCGTCCAAGCCAAGG	NPC1	ENSG00000141458	-0.401281560044531	[]	[]	-3	hSpCas9	negative selection	2586792
23573537	23573560	18	-	27260157	DLD1	viability	TGTGTTTGGTATGGAGAGTGTGG	NPC1	ENSG00000141458	-1.26756954912895	[]	[]	-7	hSpCas9	negative selection	2605483
23560314	23560337	18	+	27260157	DLD1	viability	GTCCAAGCCAAGGATCGTCCAGG	NPC1	ENSG00000141458	0.111486568650595	[]	[]	3	hSpCas9	negative selection	2605881
23586330	23586353	18	-	27260157	DLD1	viability	GGCCACAGCATGACCGCTCGCGG	NPC1	ENSG00000141458	0.0844528789806368	[]	[]	3	hSpCas9	negative selection	2607717
23561421	23561444	18	+	27260157	DLD1	viability	AATCCAGTTGGTGGCATTACAGG	NPC1	ENSG00000141458	-0.400150873974859	[]	[]	-3	hSpCas9	negative selection	2609177
23556582	23556605	18	+	27260157	DLD1	viability	TGCGCTGACAGGGTCACAGCAGG	NPC1	ENSG00000141458	-0.811423152909902	[]	[]	-6	hSpCas9	negative selection	2614338
23560280	23560303	18	-	27260157	DLD1	viability	CATCATGTGGATCACCTACATGG	NPC1	ENSG00000141458	0.936715507168286	[]	[]	9	hSpCas9	negative selection	2618318
23586307	23586330	18	+	27260157	DLD1	viability	GCAGGAGGAGGCCAAGGGCCAGG	NPC1	ENSG00000141458	1.09044946499851	[]	[]	9	hSpCas9	negative selection	2643586
23586317	23586340	18	+	27260157	DLD1	viability	GCCAAGGGCCAGGCCGCGAGCGG	NPC1	ENSG00000141458	0.500287122427968	[]	[]	8	hSpCas9	negative selection	2644411
23560434	23560457	18	+	27260157	DLD1	viability	GCCTTTGGTGGCATTGTTCATGG	NPC1	ENSG00000141458	-0.494454490577288	[]	[]	-4	hSpCas9	negative selection	2644419
23573546	23573569	18	-	27260157	HT1080	viability	TCACAGTCCTGTGTTTGGTATGG	NPC1	ENSG00000141458	-0.0654518583625935	[]	[]	0	hSpCas9	negative selection	2650726
23586292	23586315	18	+	27260157	HT1080	viability	CTGGACACAGTAGCAGCAGGAGG	NPC1	ENSG00000141458	0.482074179603055	[]	[]	4	hSpCas9	negative selection	2653349
23560412	23560435	18	-	27260157	HT1080	viability	CTGTGACGAGTCTGTGGATGAGG	NPC1	ENSG00000141458	-0.0584400765526632	[]	[]	0	hSpCas9	negative selection	2654528
23586273	23586296	18	+	27260157	HT1080	viability	CGGCGACCGCTCACCTGCGCTGG	NPC1	ENSG00000141458	-0.639318249336121	[]	[]	-8	hSpCas9	negative selection	2656615
23586301	23586324	18	+	27260157	HT1080	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-1.02281841329237	[]	[]	-8	hSpCas9	negative selection	2658915
23560316	23560339	18	-	27260157	HT1080	viability	TCCCTGGACGATCCTTGGCTTGG	NPC1	ENSG00000141458	-0.212223076472236	[]	[]	0	hSpCas9	negative selection	2660398
23560304	23560327	18	+	27260157	HT1080	viability	CATACATGGCGTCCAAGCCAAGG	NPC1	ENSG00000141458	0.657206450965577	[]	[]	6	hSpCas9	negative selection	2662922
23573537	23573560	18	-	27260157	HT1080	viability	TGTGTTTGGTATGGAGAGTGTGG	NPC1	ENSG00000141458	-1.0099432359486	[]	[]	-8	hSpCas9	negative selection	2681613
23560314	23560337	18	+	27260157	HT1080	viability	GTCCAAGCCAAGGATCGTCCAGG	NPC1	ENSG00000141458	0.939913167474407	[]	[]	7	hSpCas9	negative selection	2682011
23586330	23586353	18	-	27260157	HT1080	viability	GGCCACAGCATGACCGCTCGCGG	NPC1	ENSG00000141458	-0.251024988655304	[]	[]	0	hSpCas9	negative selection	2683847
23561421	23561444	18	+	27260157	HT1080	viability	AATCCAGTTGGTGGCATTACAGG	NPC1	ENSG00000141458	-0.0616408889317357	[]	[]	0	hSpCas9	negative selection	2685307
23556582	23556605	18	+	27260157	HT1080	viability	TGCGCTGACAGGGTCACAGCAGG	NPC1	ENSG00000141458	0.00359102869496876	[]	[]	0	hSpCas9	negative selection	2690468
23560280	23560303	18	-	27260157	HT1080	viability	CATCATGTGGATCACCTACATGG	NPC1	ENSG00000141458	1.15671641643068	[]	[]	8	hSpCas9	negative selection	2694448
23586307	23586330	18	+	27260157	HT1080	viability	GCAGGAGGAGGCCAAGGGCCAGG	NPC1	ENSG00000141458	-0.198520486525221	[]	[]	0	hSpCas9	negative selection	2719716
23586317	23586340	18	+	27260157	HT1080	viability	GCCAAGGGCCAGGCCGCGAGCGG	NPC1	ENSG00000141458	1.02190682503547	[]	[]	8	hSpCas9	negative selection	2720541
23560434	23560457	18	+	27260157	HT1080	viability	GCCTTTGGTGGCATTGTTCATGG	NPC1	ENSG00000141458	-0.0638233833241049	[]	[]	0	hSpCas9	negative selection	2720549
23573546	23573569	18	-	27260157	MKN45	viability	TCACAGTCCTGTGTTTGGTATGG	NPC1	ENSG00000141458	-0.899138995789744	[]	[]	-7	hSpCas9	negative selection	2726856
23586292	23586315	18	+	27260157	MKN45	viability	CTGGACACAGTAGCAGCAGGAGG	NPC1	ENSG00000141458	0.218394652661967	[]	[]	5	hSpCas9	negative selection	2729479
23560412	23560435	18	-	27260157	MKN45	viability	CTGTGACGAGTCTGTGGATGAGG	NPC1	ENSG00000141458	-0.511181659968091	[]	[]	-6	hSpCas9	negative selection	2730658
23586273	23586296	18	+	27260157	MKN45	viability	CGGCGACCGCTCACCTGCGCTGG	NPC1	ENSG00000141458	-1.6034236342137	[]	[]	-9	hSpCas9	negative selection	2732745
23586301	23586324	18	+	27260157	MKN45	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-0.488133021968525	[]	[]	-6	hSpCas9	negative selection	2735045
23560316	23560339	18	-	27260157	MKN45	viability	TCCCTGGACGATCCTTGGCTTGG	NPC1	ENSG00000141458	-0.638131227804703	[]	[]	-6	hSpCas9	negative selection	2736528
23560304	23560327	18	+	27260157	MKN45	viability	CATACATGGCGTCCAAGCCAAGG	NPC1	ENSG00000141458	-0.390044385324755	[]	[]	-1	hSpCas9	negative selection	2739052
23573537	23573560	18	-	27260157	MKN45	viability	TGTGTTTGGTATGGAGAGTGTGG	NPC1	ENSG00000141458	-1.83583217052075	[]	[]	-9	hSpCas9	negative selection	2757743
23560314	23560337	18	+	27260157	MKN45	viability	GTCCAAGCCAAGGATCGTCCAGG	NPC1	ENSG00000141458	-0.0717168279173433	[]	[]	0	hSpCas9	negative selection	2758141
23586330	23586353	18	-	27260157	MKN45	viability	GGCCACAGCATGACCGCTCGCGG	NPC1	ENSG00000141458	0.361577814018878	[]	[]	6	hSpCas9	negative selection	2759977
23561421	23561444	18	+	27260157	MKN45	viability	AATCCAGTTGGTGGCATTACAGG	NPC1	ENSG00000141458	-0.0662485448189666	[]	[]	0	hSpCas9	negative selection	2761437
23556582	23556605	18	+	27260157	MKN45	viability	TGCGCTGACAGGGTCACAGCAGG	NPC1	ENSG00000141458	-1.5765628568603	[]	[]	-9	hSpCas9	negative selection	2766598
23560280	23560303	18	-	27260157	MKN45	viability	CATCATGTGGATCACCTACATGG	NPC1	ENSG00000141458	0.962446708846168	[]	[]	8	hSpCas9	negative selection	2770578
23586307	23586330	18	+	27260157	MKN45	viability	GCAGGAGGAGGCCAAGGGCCAGG	NPC1	ENSG00000141458	1.45600592112098	[]	[]	9	hSpCas9	negative selection	2795846
23586317	23586340	18	+	27260157	MKN45	viability	GCCAAGGGCCAGGCCGCGAGCGG	NPC1	ENSG00000141458	0.150268526582002	[]	[]	5	hSpCas9	negative selection	2796671
23560434	23560457	18	+	27260157	MKN45	viability	GCCTTTGGTGGCATTGTTCATGG	NPC1	ENSG00000141458	0.447994795367614	[]	[]	6	hSpCas9	negative selection	2796679
23573546	23573569	18	-	27260157	RKO	viability	TCACAGTCCTGTGTTTGGTATGG	NPC1	ENSG00000141458	0.304854037860831	[]	[]	1	hSpCas9	negative selection	2802986
23586292	23586315	18	+	27260157	RKO	viability	CTGGACACAGTAGCAGCAGGAGG	NPC1	ENSG00000141458	0.48114668633173	[]	[]	2	hSpCas9	negative selection	2805609
23560412	23560435	18	-	27260157	RKO	viability	CTGTGACGAGTCTGTGGATGAGG	NPC1	ENSG00000141458	-0.493191174872833	[]	[]	-6	hSpCas9	negative selection	2806788
23586273	23586296	18	+	27260157	RKO	viability	CGGCGACCGCTCACCTGCGCTGG	NPC1	ENSG00000141458	-1.08242222844139	[]	[]	-8	hSpCas9	negative selection	2808875
23586301	23586324	18	+	27260157	RKO	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-0.666378347211582	[]	[]	-7	hSpCas9	negative selection	2811175
23560316	23560339	18	-	27260157	RKO	viability	TCCCTGGACGATCCTTGGCTTGG	NPC1	ENSG00000141458	-0.209232418349388	[]	[]	-1	hSpCas9	negative selection	2812658
23560304	23560327	18	+	27260157	RKO	viability	CATACATGGCGTCCAAGCCAAGG	NPC1	ENSG00000141458	0.296422308214465	[]	[]	1	hSpCas9	negative selection	2815182
23573537	23573560	18	-	27260157	RKO	viability	TGTGTTTGGTATGGAGAGTGTGG	NPC1	ENSG00000141458	0.0107432313851004	[]	[]	0	hSpCas9	negative selection	2833873
23560314	23560337	18	+	27260157	RKO	viability	GTCCAAGCCAAGGATCGTCCAGG	NPC1	ENSG00000141458	1.86791934565163	[]	[]	9	hSpCas9	negative selection	2834271
23586330	23586353	18	-	27260157	RKO	viability	GGCCACAGCATGACCGCTCGCGG	NPC1	ENSG00000141458	0.346995289409317	[]	[]	1	hSpCas9	negative selection	2836107
23561421	23561444	18	+	27260157	RKO	viability	AATCCAGTTGGTGGCATTACAGG	NPC1	ENSG00000141458	0.639716531276462	[]	[]	3	hSpCas9	negative selection	2837567
23556582	23556605	18	+	27260157	RKO	viability	TGCGCTGACAGGGTCACAGCAGG	NPC1	ENSG00000141458	-0.514625368193884	[]	[]	-6	hSpCas9	negative selection	2842728
23560280	23560303	18	-	27260157	RKO	viability	CATCATGTGGATCACCTACATGG	NPC1	ENSG00000141458	1.42097250654308	[]	[]	9	hSpCas9	negative selection	2846708
23586307	23586330	18	+	27260157	RKO	viability	GCAGGAGGAGGCCAAGGGCCAGG	NPC1	ENSG00000141458	0.618479040214076	[]	[]	3	hSpCas9	negative selection	2871976
23586317	23586340	18	+	27260157	RKO	viability	GCCAAGGGCCAGGCCGCGAGCGG	NPC1	ENSG00000141458	0.40161471531439	[]	[]	2	hSpCas9	negative selection	2872801
23560434	23560457	18	+	27260157	RKO	viability	GCCTTTGGTGGCATTGTTCATGG	NPC1	ENSG00000141458	-0.286828229201112	[]	[]	-5	hSpCas9	negative selection	2872809
23573546	23573569	18	-	27260157	SF268	viability	TCACAGTCCTGTGTTTGGTATGG	NPC1	ENSG00000141458	-0.801970352019631	[]	[]	-6	hSpCas9	negative selection	2879116
23586292	23586315	18	+	27260157	SF268	viability	CTGGACACAGTAGCAGCAGGAGG	NPC1	ENSG00000141458	0.338155967528203	[]	[]	4	hSpCas9	negative selection	2881739
23560412	23560435	18	-	27260157	SF268	viability	CTGTGACGAGTCTGTGGATGAGG	NPC1	ENSG00000141458	0.00837721250740387	[]	[]	0	hSpCas9	negative selection	2882918
23586273	23586296	18	+	27260157	SF268	viability	CGGCGACCGCTCACCTGCGCTGG	NPC1	ENSG00000141458	-1.29233692376286	[]	[]	-7	hSpCas9	negative selection	2885005
23586301	23586324	18	+	27260157	SF268	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-1.09133992748244	[]	[]	-7	hSpCas9	negative selection	2887305
23560316	23560339	18	-	27260157	SF268	viability	TCCCTGGACGATCCTTGGCTTGG	NPC1	ENSG00000141458	-0.335732270246754	[]	[]	-3	hSpCas9	negative selection	2888788
23560304	23560327	18	+	27260157	SF268	viability	CATACATGGCGTCCAAGCCAAGG	NPC1	ENSG00000141458	0.0525537060123221	[]	[]	0	hSpCas9	negative selection	2891312
23573537	23573560	18	-	27260157	SF268	viability	TGTGTTTGGTATGGAGAGTGTGG	NPC1	ENSG00000141458	-1.4149271159433	[]	[]	-8	hSpCas9	negative selection	2910003
23560314	23560337	18	+	27260157	SF268	viability	GTCCAAGCCAAGGATCGTCCAGG	NPC1	ENSG00000141458	-0.357621487560484	[]	[]	-3	hSpCas9	negative selection	2910401
23586330	23586353	18	-	27260157	SF268	viability	GGCCACAGCATGACCGCTCGCGG	NPC1	ENSG00000141458	-0.839605276052287	[]	[]	-6	hSpCas9	negative selection	2912237
23561421	23561444	18	+	27260157	SF268	viability	AATCCAGTTGGTGGCATTACAGG	NPC1	ENSG00000141458	-0.954416898112504	[]	[]	-6	hSpCas9	negative selection	2913697
23556582	23556605	18	+	27260157	SF268	viability	TGCGCTGACAGGGTCACAGCAGG	NPC1	ENSG00000141458	-0.790849638716626	[]	[]	-6	hSpCas9	negative selection	2918858
23560280	23560303	18	-	27260157	SF268	viability	CATCATGTGGATCACCTACATGG	NPC1	ENSG00000141458	0.621848076552359	[]	[]	8	hSpCas9	negative selection	2922838
23586307	23586330	18	+	27260157	SF268	viability	GCAGGAGGAGGCCAAGGGCCAGG	NPC1	ENSG00000141458	1.17581663551633	[]	[]	9	hSpCas9	negative selection	2948106
23586317	23586340	18	+	27260157	SF268	viability	GCCAAGGGCCAGGCCGCGAGCGG	NPC1	ENSG00000141458	0.598427852942719	[]	[]	8	hSpCas9	negative selection	2948931
23560434	23560457	18	+	27260157	SF268	viability	GCCTTTGGTGGCATTGTTCATGG	NPC1	ENSG00000141458	-0.439120804827881	[]	[]	-3	hSpCas9	negative selection	2948939
23556260	23556283	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGTCAAGCGGAGGTCCAAAGGG	NPC1	ENSG00000141458	0.024769816693846786	[2,2]	[3,1]	0	hSpCas9	positive selection	3006192
23556353	23556376	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTTGGGCCTTTCTTCCGGACGG	NPC1	ENSG00000141458	-0.080558905959	[5,5]	[4,3]	-1	hSpCas9	positive selection	3006193
23548025	23548048	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGATACAGAGAAGCTCCAGAGGG	NPC1	ENSG00000141458	0.1645166886219774	[3,3]	[1,3]	3	hSpCas9	positive selection	3006194
23561351	23561374	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATACCTACCTGAAAACACAGG	NPC1	ENSG00000141458	-0.28397150939492066	[4,4]	[2,2]	-4	hSpCas9	positive selection	3006195
23556260	23556283	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGTCAAGCGGAGGTCCAAAGGG	NPC1	ENSG00000141458	-0.07129815096209843	[2,2]	[0,2]	-1	hSpCas9	positive selection	3074050
23556353	23556376	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTTGGGCCTTTCTTCCGGACGG	NPC1	ENSG00000141458	-0.0028644054264818086	[5,5]	[4,3]	0	hSpCas9	positive selection	3074051
23548025	23548048	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGATACAGAGAAGCTCCAGAGGG	NPC1	ENSG00000141458	0.10781628433830598	[3,3]	[1,2]	2	hSpCas9	positive selection	3074052
23561351	23561374	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATACCTACCTGAAAACACAGG	NPC1	ENSG00000141458	0.3122129332917284	[4,4]	[4,3]	5	hSpCas9	positive selection	3074053
23568840	23568863		-	24336571	A375	resistance to PLX after 7 days	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.14947950935839066	[8,10]	[7,8]	-5	hSpCas9	positive selection	3131294
23561444	23561467		+	24336571	A375	resistance to PLX after 7 days	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.3920427260967074	[8,10]	[12,13]	8	hSpCas9	positive selection	3131295
23561477	23561500		-	24336571	A375	resistance to PLX after 7 days	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	0.24809085171685386	[4,10]	[9,8]	7	hSpCas9	positive selection	3131296
23568921	23568944		+	24336571	A375	resistance to PLX after 7 days	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.2366174989349532	[6,6]	[9,6]	7	hSpCas9	positive selection	3131297
23568840	23568863		-	24336571	A375	resistance to PLX after 14 days	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.1106844545785729	[5,8]	[3,1]	-1	hSpCas9	positive selection	3189087
23561444	23561467		+	24336571	A375	resistance to PLX after 14 days	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	2.109077937936659	[11,6]	[17,21]	9	hSpCas9	positive selection	3189088
23561477	23561500		-	24336571	A375	resistance to PLX after 14 days	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	0.44295258721586717	[6,9]	[4,4]	4	hSpCas9	positive selection	3189089
23568921	23568944		+	24336571	A375	resistance to PLX after 14 days	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.6289996444019725	[4,7]	[3,4]	5	hSpCas9	positive selection	3189090
23568840	23568863		-	24336571	A375	viability after 7 days	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.6354484612804987	[16]	[8,10]	-7	hSpCas9	negative selection	3246880
23561444	23561467		+	24336571	A375	viability after 7 days	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.4335507581760473	[7]	[8,10]	6	hSpCas9	negative selection	3246881
23561477	23561500		-	24336571	A375	viability after 7 days	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.9510317107868846	[16]	[4,10]	-8	hSpCas9	negative selection	3246882
23568921	23568944		+	24336571	A375	viability after 7 days	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.3842210164454637	[5]	[6,6]	6	hSpCas9	negative selection	3246883
23568840	23568863		-	24336571	A375	viability after 14 days	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-1.0324271555567779	[16]	[5,8]	-8	hSpCas9	negative selection	3304673
23561444	23561467		+	24336571	A375	viability after 14 days	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.37714554381122506	[7]	[11,6]	5	hSpCas9	negative selection	3304674
23561477	23561500		-	24336571	A375	viability after 14 days	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.9103204935369608	[16]	[6,9]	-8	hSpCas9	negative selection	3304675
23568921	23568944		+	24336571	A375	viability after 14 days	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.22848017158373668	[5]	[4,7]	3	hSpCas9	negative selection	3304676
23561477	23561500	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	0.36250844813789157	[118,118]	[0,0]	2	hSpCas9	positive selection	3382154
23557116	23557139	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.8822251409529586	[281,281]	[0,0]	-6	hSpCas9	positive selection	3382155
23568921	23568944	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	1.1912370209880627	[66,66]	[0,0]	5	hSpCas9	positive selection	3382156
23556259	23556282	18	+	26780180	HT29	viability (Avana library 4 designs)	ATGTCAAGCGGAGGTCCAAAGGG	NPC1	ENSG00000141458	1.86569502702283	[]	[]	7	hSpCas9	negative selection	3444050
23556353	23556376	18	-	26780180	HT29	viability (Avana library 4 designs)	CTTTGGGCCTTTCTTCCGGACGG	NPC1	ENSG00000141458	0.271577082789369	[]	[]	0	hSpCas9	negative selection	3444051
23548025	23548048	18	-	26780180	HT29	viability (Avana library 4 designs)	TGATACAGAGAAGCTCCAGAGGG	NPC1	ENSG00000141458	3.66892060911996	[]	[]	9	hSpCas9	negative selection	3444052
23561350	23561373	18	+	26780180	HT29	viability (Avana library 4 designs)	TTATACCTACCTGAAAACACAGG	NPC1	ENSG00000141458	1.48122902933371	[]	[]	6	hSpCas9	negative selection	3444053
23548025	23548048	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGATACAGAGAAGCTCCAGAGGG	NPC1	ENSG00000141458	-12.2639034189083	[]	[]	-8	hSpCas9	negative selection	3536044
23556353	23556376	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTTGGGCCTTTCTTCCGGACGG	NPC1	ENSG00000141458	4.38802766108122	[]	[]	7	hSpCas9	negative selection	3536045
23556259	23556282	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGTCAAGCGGAGGTCCAAAGGG	NPC1	ENSG00000141458	5.03884569501992	[]	[]	8	hSpCas9	negative selection	3536046
23561350	23561373	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATACCTACCTGAAAACACAGG	NPC1	ENSG00000141458	-14.9225945786589	[]	[]	-9	hSpCas9	negative selection	3536047
23545017	23545040	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGGCATAGCTAATTACAACGG	NPC1	ENSG00000141458	-6.95281900560264	[]	[]	-6	hSpCas9	negative selection	3536048
23548062	23548085	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACAGGGAAGGTAATCACAAGGG	NPC1	ENSG00000141458	-1.64376499209949	[]	[]	-2	hSpCas9	negative selection	3536049
23548025	23548048	18	-	26780180	A375	viability (Avana lentiGuide)	TGATACAGAGAAGCTCCAGAGGG	NPC1	ENSG00000141458	10.5346275181647	[]	[]	7	hSpCas9	negative selection	3644703
23556353	23556376	18	-	26780180	A375	viability (Avana lentiGuide)	CTTTGGGCCTTTCTTCCGGACGG	NPC1	ENSG00000141458	5.46714800819428	[]	[]	5	hSpCas9	negative selection	3644704
23556259	23556282	18	+	26780180	A375	viability (Avana lentiGuide)	ATGTCAAGCGGAGGTCCAAAGGG	NPC1	ENSG00000141458	0.21896326116377	[]	[]	0	hSpCas9	negative selection	3644705
23561350	23561373	18	+	26780180	A375	viability (Avana lentiGuide)	TTATACCTACCTGAAAACACAGG	NPC1	ENSG00000141458	13.3068514231213	[]	[]	7	hSpCas9	negative selection	3644706
23545017	23545040	18	+	26780180	A375	viability (Avana lentiGuide)	GATGGCATAGCTAATTACAACGG	NPC1	ENSG00000141458	13.8606873458687	[]	[]	7	hSpCas9	negative selection	3644707
23548062	23548085	18	+	26780180	A375	viability (Avana lentiGuide)	GACAGGGAAGGTAATCACAAGGG	NPC1	ENSG00000141458	13.0734493823645	[]	[]	7	hSpCas9	negative selection	3644708
23548025	23548048	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATACAGAGAAGCTCCAGAGGG	NPC1	ENSG00000141458	-0.3791393595148418	[5]	[3,3]	-5	hSpCas9	positive selection	3753362
23556353	23556376	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTTGGGCCTTTCTTCCGGACGG	NPC1	ENSG00000141458	0.15515914925258217	[6]	[6,6]	4	hSpCas9	positive selection	3753363
23556259	23556282	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGTCAAGCGGAGGTCCAAAGGG	NPC1	ENSG00000141458	0.20678692274755256	[4]	[5,4]	6	hSpCas9	positive selection	3753364
23561350	23561373	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATACCTACCTGAAAACACAGG	NPC1	ENSG00000141458	-0.8401336744530747	[6]	[3,3]	-8	hSpCas9	positive selection	3753365
23545017	23545040	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGGCATAGCTAATTACAACGG	NPC1	ENSG00000141458	-0.26008775431725956	[5]	[4,4]	-4	hSpCas9	positive selection	3753366
23548062	23548085	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACAGGGAAGGTAATCACAAGGG	NPC1	ENSG00000141458	-0.08784106286979573	[4]	[3,3]	-1	hSpCas9	positive selection	3753367
23548025	23548048	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATACAGAGAAGCTCCAGAGGG	NPC1	ENSG00000141458	0.21026846600407953	[5]	[5,4]	5	hSpCas9	positive selection	3861969
23556353	23556376	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTTGGGCCTTTCTTCCGGACGG	NPC1	ENSG00000141458	-0.042979962823731455	[7]	[7,4]	0	hSpCas9	positive selection	3861970
23556259	23556282	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGTCAAGCGGAGGTCCAAAGGG	NPC1	ENSG00000141458	-0.3043550627200927	[4]	[3,2]	-4	hSpCas9	positive selection	3861971
23561350	23561373	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATACCTACCTGAAAACACAGG	NPC1	ENSG00000141458	0.12410689611483669	[6]	[6,5]	3	hSpCas9	positive selection	3861972
23545017	23545040	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGGCATAGCTAATTACAACGG	NPC1	ENSG00000141458	-0.22003783206231653	[5]	[2,4]	-3	hSpCas9	positive selection	3861973
23548062	23548085	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACAGGGAAGGTAATCACAAGGG	NPC1	ENSG00000141458	-0.5203813909454382	[4]	[2,2]	-6	hSpCas9	positive selection	3861974
23557139	23557162	18	+	26780180	A375	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	1.13867631383757	[]	[]	6	hSpCas9	negative selection	3973289
23568840	23568863	18	-	26780180	A375	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	1.57318265148535	[]	[]	8	hSpCas9	negative selection	3973290
23561444	23561467	18	+	26780180	A375	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.37789237911763	[]	[]	0	hSpCas9	negative selection	3973291
23561477	23561500	18	-	26780180	A375	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	1.20001899476748	[]	[]	6	hSpCas9	negative selection	3973292
23557116	23557139	18	-	26780180	A375	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	1.38597278630473	[]	[]	7	hSpCas9	negative selection	3973293
23568921	23568944	18	+	26780180	A375	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.992287610353014	[]	[]	4	hSpCas9	negative selection	3973294
23557139	23557162	18	+	26780180	HT29	viability (GeCKOv2 library)	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	1.06165467152086	[]	[]	5	hSpCas9	negative selection	4081255
23568840	23568863	18	-	26780180	HT29	viability (GeCKOv2 library)	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	2.02625572921723	[]	[]	9	hSpCas9	negative selection	4081256
23561444	23561467	18	+	26780180	HT29	viability (GeCKOv2 library)	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.364228893907742	[]	[]	1	hSpCas9	negative selection	4081257
23561477	23561500	18	-	26780180	HT29	viability (GeCKOv2 library)	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	1.31735691889409	[]	[]	6	hSpCas9	negative selection	4081258
23557116	23557139	18	-	26780180	HT29	viability (GeCKOv2 library)	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.917680656345916	[]	[]	4	hSpCas9	negative selection	4081259
23568921	23568944	18	+	26780180	HT29	viability (GeCKOv2 library)	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	1.34667681032331	[]	[]	6	hSpCas9	negative selection	4081260
23568840	23568863	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.18099062414671063	[2]	[1,1]	-4	hSpCas9	positive selection	4155988
23561444	23561467	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.5062735473357376	[2]	[1,4]	9	hSpCas9	positive selection	4155989
23561477	23561500	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	0.24460307644738374	[2]	[2,2]	6	hSpCas9	positive selection	4155990
23568921	23568944	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.1490942569884003	[2]	[1,1]	4	hSpCas9	positive selection	4155991
23515929	23515952	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.1386669818451709	[3]	[2,3]	3	hSpCas9	positive selection	4186255
23515939	23515962	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTGATCTTGCTGTCTACCACGG	NPC1	ENSG00000141458	0.20285364626561644	[3]	[2,2]	5	hSpCas9	positive selection	4186257
23568840	23568863	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	0.02751746171521427	[3]	[1,1,0,0]	0	hSpCas9	positive selection	4220010
23561444	23561467	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.6634543879115664	[1]	[0,0,1,0]	4	hSpCas9	positive selection	4220011
23561477	23561500	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.2407310746021174	[4]	[0,0,4,0]	-4	hSpCas9	positive selection	4220012
23568921	23568944	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	-0.03647976736259051	[1]	[0,0,0,0]	0	hSpCas9	positive selection	4220013
23515929	23515952	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	-0.5573668052435661	[3]	[0,1,0,0]	-7	hSpCas9	positive selection	4250277
23515939	23515962	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTGATCTTGCTGTCTACCACGG	NPC1	ENSG00000141458	-0.4338630922570436	[4]	[0,3,1,0]	-6	hSpCas9	positive selection	4250279
23515929	23515952	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	-0.07700565045427693	[3]	[3,1]	-1	hSpCas9	positive selection	4259325
23516394	23516417	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-0.13952877558788646	[1]	[1,0]	-3	hSpCas9	positive selection	4259326
23515862	23515885	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.041972735495611924	[3]	[3,1]	0	hSpCas9	positive selection	4259327
23557139	23557162	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	0.276183297555074	[3]	[3,3]	5	hSpCas9	positive selection	4286073
23568840	23568863	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.1683796010387704	[2]	[0,2]	-3	hSpCas9	positive selection	4286074
23561444	23561467	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.35826481432506574	[0]	[1,0]	7	hSpCas9	positive selection	4286075
23516396	23516419	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.5434689479136765	[3]	[4,4]	9	hSpCas9	positive selection	4323607
23561477	23561500	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.26911653255742596	[2]	[2,0]	-5	hSpCas9	positive selection	4350330
23557116	23557139	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.5072535176905185	[3]	[3,4]	9	hSpCas9	positive selection	4350331
23568921	23568944	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.3276961198796663	[2]	[3,0]	6	hSpCas9	positive selection	4350332
23551667	23551689	18	+	27760321	OCIAML3	viability	ACCAAACGTACCCAGACAAGGG	NPC1	ENSG00000141458	0.30533486730127657	[444,352]	[275,522]	3	hSpCas9	negative selection	4423116
23554879	23554901	18	+	27760321	OCIAML3	viability	TCGTGTTATACGGTGAAAGAGG	NPC1	ENSG00000141458	0.6530288721745925	[97,83]	[88,140]	7	hSpCas9	negative selection	4423117
23556279	23556301	18	+	27760321	OCIAML3	viability	GGGTACATCAGCTCCCGAAGGG	NPC1	ENSG00000141458	0.3483252332042404	[563,525]	[373,762]	4	hSpCas9	negative selection	4423118
23556464	23556486	18	-	27760321	OCIAML3	viability	ACTGCGTGTTCGTCAGGCCTGG	NPC1	ENSG00000141458	0.25633243926251614	[1061,926]	[912,944]	3	hSpCas9	negative selection	4423119
23556541	23556563	18	-	27760321	OCIAML3	viability	GGCGGCTGTTCACACGCTGGGG	NPC1	ENSG00000141458	-0.0020798364446141804	[1376,1169]	[886,1126]	0	hSpCas9	negative selection	4423120
23551667	23551689	18	+	27760321	OCIAML2	viability	ACCAAACGTACCCAGACAAGGG	NPC1	ENSG00000141458	-0.14694258496375753	[444,352]	[205,399]	-2	hSpCas9	negative selection	4506579
23554879	23554901	18	+	27760321	OCIAML2	viability	TCGTGTTATACGGTGAAAGAGG	NPC1	ENSG00000141458	0.38821143518529766	[97,83]	[108,78]	5	hSpCas9	negative selection	4506580
23556279	23556301	18	+	27760321	OCIAML2	viability	GGGTACATCAGCTCCCGAAGGG	NPC1	ENSG00000141458	0.35356959100169644	[563,525]	[522,616]	5	hSpCas9	negative selection	4506581
23556464	23556486	18	-	27760321	OCIAML2	viability	ACTGCGTGTTCGTCAGGCCTGG	NPC1	ENSG00000141458	0.16505898857340262	[1061,926]	[779,1057]	2	hSpCas9	negative selection	4506582
23556541	23556563	18	-	27760321	OCIAML2	viability	GGCGGCTGTTCACACGCTGGGG	NPC1	ENSG00000141458	0.13223236880035394	[1376,1169]	[959,1342]	1	hSpCas9	negative selection	4506583
23551667	23551689	18	+	27760321	MV411	viability	ACCAAACGTACCCAGACAAGGG	NPC1	ENSG00000141458	-0.10966898377219372	[444,352]	[144,388]	-1	hSpCas9	negative selection	4590042
23554879	23554901	18	+	27760321	MV411	viability	TCGTGTTATACGGTGAAAGAGG	NPC1	ENSG00000141458	0.8365438682417841	[97,83]	[0,265]	6	hSpCas9	negative selection	4590043
23556279	23556301	18	+	27760321	MV411	viability	GGGTACATCAGCTCCCGAAGGG	NPC1	ENSG00000141458	-1.0817223623915613	[563,525]	[159,184]	-6	hSpCas9	negative selection	4590044
23556464	23556486	18	-	27760321	MV411	viability	ACTGCGTGTTCGTCAGGCCTGG	NPC1	ENSG00000141458	1.3518485361652888	[1061,926]	[1705,1618]	8	hSpCas9	negative selection	4590045
23556541	23556563	18	-	27760321	MV411	viability	GGCGGCTGTTCACACGCTGGGG	NPC1	ENSG00000141458	0.398705697317421	[1376,1169]	[797,1563]	3	hSpCas9	negative selection	4590046
23551667	23551689	18	+	27760321	HL60	viability	ACCAAACGTACCCAGACAAGGG	NPC1	ENSG00000141458	-0.02674346546674075	[444,352]	[316,318]	0	hSpCas9	negative selection	4673505
23554879	23554901	18	+	27760321	HL60	viability	TCGTGTTATACGGTGAAAGAGG	NPC1	ENSG00000141458	0.7218977695616695	[97,83]	[129,113]	8	hSpCas9	negative selection	4673506
23556279	23556301	18	+	27760321	HL60	viability	GGGTACATCAGCTCCCGAAGGG	NPC1	ENSG00000141458	0.5524974622491612	[563,525]	[709,592]	6	hSpCas9	negative selection	4673507
23556464	23556486	18	-	27760321	HL60	viability	ACTGCGTGTTCGTCAGGCCTGG	NPC1	ENSG00000141458	0.10195514616438306	[1061,926]	[782,961]	1	hSpCas9	negative selection	4673508
23556541	23556563	18	-	27760321	HL60	viability	GGCGGCTGTTCACACGCTGGGG	NPC1	ENSG00000141458	0.0016296930265846665	[1376,1169]	[1035,1039]	0	hSpCas9	negative selection	4673509
23551667	23551689	18	+	27760321	HT1080	viability	ACCAAACGTACCCAGACAAGGG	NPC1	ENSG00000141458	-0.058019298643243455	[352,275]	[127,111]	0	hSpCas9	negative selection	4756968
23554879	23554901	18	+	27760321	HT1080	viability	TCGTGTTATACGGTGAAAGAGG	NPC1	ENSG00000141458	0.30526921320156797	[83,65]	[24,49]	1	hSpCas9	negative selection	4756969
23556279	23556301	18	+	27760321	HT1080	viability	GGGTACATCAGCTCCCGAAGGG	NPC1	ENSG00000141458	1.9072707264108906	[525,410]	[923,454]	8	hSpCas9	negative selection	4756970
23556464	23556486	18	-	27760321	HT1080	viability	ACTGCGTGTTCGTCAGGCCTGG	NPC1	ENSG00000141458	1.0275920034321127	[926,723]	[900,417]	5	hSpCas9	negative selection	4756971
23556541	23556563	18	-	27760321	HT1080	viability	GGCGGCTGTTCACACGCTGGGG	NPC1	ENSG00000141458	0.2400833410606158	[1169,912]	[637,327]	1	hSpCas9	negative selection	4756972
23551667	23551689	18	+	27760321	HT29	viability after 7 days	ACCAAACGTACCCAGACAAGGG	NPC1	ENSG00000141458	0.2745685839769554	[352,275]	[663,282,542]	4	hSpCas9	negative selection	4840431
23554879	23554901	18	+	27760321	HT29	viability after 7 days	TCGTGTTATACGGTGAAAGAGG	NPC1	ENSG00000141458	-0.3275029617740346	[83,65]	[52,29,141]	-5	hSpCas9	negative selection	4840432
23556279	23556301	18	+	27760321	HT29	viability after 7 days	GGGTACATCAGCTCCCGAAGGG	NPC1	ENSG00000141458	0.12761073446900023	[525,410]	[567,653,735]	2	hSpCas9	negative selection	4840433
23556464	23556486	18	-	27760321	HT29	viability after 7 days	ACTGCGTGTTCGTCAGGCCTGG	NPC1	ENSG00000141458	0.3772398908395105	[926,723]	[1531,1095,1522]	6	hSpCas9	negative selection	4840434
23556541	23556563	18	-	27760321	HT29	viability after 7 days	GGCGGCTGTTCACACGCTGGGG	NPC1	ENSG00000141458	0.2640142636422669	[1169,912]	[1687,1442,1698]	4	hSpCas9	negative selection	4840435
23551667	23551689	18	+	27760321	HT29	viability after 25 days	ACCAAACGTACCCAGACAAGGG	NPC1	ENSG00000141458	-0.383920472982859	[352,275]	[154,321,365]	-4	hSpCas9	negative selection	4923894
23554879	23554901	18	+	27760321	HT29	viability after 25 days	TCGTGTTATACGGTGAAAGAGG	NPC1	ENSG00000141458	-0.9533104144424511	[83,65]	[46,37,47]	-6	hSpCas9	negative selection	4923895
23556279	23556301	18	+	27760321	HT29	viability after 25 days	GGGTACATCAGCTCCCGAAGGG	NPC1	ENSG00000141458	-0.5986153447053325	[525,410]	[320,381,359]	-5	hSpCas9	negative selection	4923896
23556464	23556486	18	-	27760321	HT29	viability after 25 days	ACTGCGTGTTCGTCAGGCCTGG	NPC1	ENSG00000141458	0.36042112515108893	[926,723]	[1168,1024,1466]	4	hSpCas9	negative selection	4923897
23556541	23556563	18	-	27760321	HT29	viability after 25 days	GGCGGCTGTTCACACGCTGGGG	NPC1	ENSG00000141458	-0.5640622519590761	[1169,912]	[795,714,914]	-5	hSpCas9	negative selection	4923898
23551667	23551689	18	+	27760321	HT29	viability after 22 days	ACCAAACGTACCCAGACAAGGG	NPC1	ENSG00000141458	-0.4779407260913027	[352,275]	[224,318,239]	-4	hSpCas9	negative selection	5007357
23554879	23554901	18	+	27760321	HT29	viability after 22 days	TCGTGTTATACGGTGAAAGAGG	NPC1	ENSG00000141458	-1.485282474254582	[83,65]	[30,24,36]	-7	hSpCas9	negative selection	5007358
23556279	23556301	18	+	27760321	HT29	viability after 22 days	GGGTACATCAGCTCCCGAAGGG	NPC1	ENSG00000141458	-0.3884676481194218	[525,410]	[380,366,494]	-4	hSpCas9	negative selection	5007359
23556464	23556486	18	-	27760321	HT29	viability after 22 days	ACTGCGTGTTCGTCAGGCCTGG	NPC1	ENSG00000141458	0.45564198766364306	[926,723]	[1333,1039,1553]	5	hSpCas9	negative selection	5007360
23556541	23556563	18	-	27760321	HT29	viability after 22 days	GGCGGCTGTTCACACGCTGGGG	NPC1	ENSG00000141458	-0.34431583183042713	[1169,912]	[942,1083,816]	-3	hSpCas9	negative selection	5007361
23551667	23551689	18	+	27760321	HT29	viability after 19 days	ACCAAACGTACCCAGACAAGGG	NPC1	ENSG00000141458	-0.6026419315117073	[352,275]	[220,334,155]	-5	hSpCas9	negative selection	5090820
23554879	23554901	18	+	27760321	HT29	viability after 19 days	TCGTGTTATACGGTGAAAGAGG	NPC1	ENSG00000141458	-1.6961794429991262	[83,65]	[41,37,1]	-7	hSpCas9	negative selection	5090821
23556279	23556301	18	+	27760321	HT29	viability after 19 days	GGGTACATCAGCTCCCGAAGGG	NPC1	ENSG00000141458	0.3213306208916777	[525,410]	[489,980,523]	3	hSpCas9	negative selection	5090822
23556464	23556486	18	-	27760321	HT29	viability after 19 days	ACTGCGTGTTCGTCAGGCCTGG	NPC1	ENSG00000141458	0.3212781545313341	[926,723]	[1264,992,1284]	3	hSpCas9	negative selection	5090823
23556541	23556563	18	-	27760321	HT29	viability after 19 days	GGCGGCTGTTCACACGCTGGGG	NPC1	ENSG00000141458	-0.4205855688369997	[1169,912]	[664,886,1085]	-4	hSpCas9	negative selection	5090824
23551667	23551689	18	+	27760321	HT29	viability after 16 days	ACCAAACGTACCCAGACAAGGG	NPC1	ENSG00000141458	0.3889331717931443	[352,275]	[477,342,565]	4	hSpCas9	negative selection	5174283
23554879	23554901	18	+	27760321	HT29	viability after 16 days	TCGTGTTATACGGTGAAAGAGG	NPC1	ENSG00000141458	0.12944077653827257	[83,65]	[212,49,24]	1	hSpCas9	negative selection	5174284
23556279	23556301	18	+	27760321	HT29	viability after 16 days	GGGTACATCAGCTCCCGAAGGG	NPC1	ENSG00000141458	0.23033989262170534	[525,410]	[986,456,439]	2	hSpCas9	negative selection	5174285
23556464	23556486	18	-	27760321	HT29	viability after 16 days	ACTGCGTGTTCGTCAGGCCTGG	NPC1	ENSG00000141458	0.4898846050201071	[926,723]	[1810,1163,967]	5	hSpCas9	negative selection	5174286
23556541	23556563	18	-	27760321	HT29	viability after 16 days	GGCGGCTGTTCACACGCTGGGG	NPC1	ENSG00000141458	-0.12020043973146466	[1169,912]	[1389,883,976]	-1	hSpCas9	negative selection	5174287
23551667	23551689	18	+	27760321	HT29	viability after 13 days	ACCAAACGTACCCAGACAAGGG	NPC1	ENSG00000141458	-0.10005135576648322	[352,275]	[338,285,392]	-1	hSpCas9	negative selection	5257746
23554879	23554901	18	+	27760321	HT29	viability after 13 days	TCGTGTTATACGGTGAAAGAGG	NPC1	ENSG00000141458	-0.6346605134497945	[83,65]	[4,67,92]	-6	hSpCas9	negative selection	5257747
23556279	23556301	18	+	27760321	HT29	viability after 13 days	GGGTACATCAGCTCCCGAAGGG	NPC1	ENSG00000141458	-0.3120391352563492	[525,410]	[379,707,237]	-4	hSpCas9	negative selection	5257748
23556464	23556486	18	-	27760321	HT29	viability after 13 days	ACTGCGTGTTCGTCAGGCCTGG	NPC1	ENSG00000141458	0.2225456324948054	[926,723]	[890,906,1528]	2	hSpCas9	negative selection	5257749
23556541	23556563	18	-	27760321	HT29	viability after 13 days	GGCGGCTGTTCACACGCTGGGG	NPC1	ENSG00000141458	-0.4543240054062019	[1169,912]	[591,813,1218]	-5	hSpCas9	negative selection	5257750
23551667	23551689	18	+	27760321	HT29	viability after 10 days	ACCAAACGTACCCAGACAAGGG	NPC1	ENSG00000141458	0.25849949049470333	[352,275]	[411,730,277]	3	hSpCas9	negative selection	5341209
23554879	23554901	18	+	27760321	HT29	viability after 10 days	TCGTGTTATACGGTGAAAGAGG	NPC1	ENSG00000141458	-0.9379649332526165	[83,65]	[17,68,59]	-7	hSpCas9	negative selection	5341210
23556279	23556301	18	+	27760321	HT29	viability after 10 days	GGGTACATCAGCTCCCGAAGGG	NPC1	ENSG00000141458	-0.209678113498827	[525,410]	[617,525,376]	-3	hSpCas9	negative selection	5341211
23556464	23556486	18	-	27760321	HT29	viability after 10 days	ACTGCGTGTTCGTCAGGCCTGG	NPC1	ENSG00000141458	0.2916687671096996	[926,723]	[1414,1096,1267]	4	hSpCas9	negative selection	5341212
23556541	23556563	18	-	27760321	HT29	viability after 10 days	GGCGGCTGTTCACACGCTGGGG	NPC1	ENSG00000141458	0.1347491732473265	[1169,912]	[1161,1390,1721]	1	hSpCas9	negative selection	5341213
23551667	23551689	18	+	27760321	MOLM13	viability	ACCAAACGTACCCAGACAAGGG	NPC1	ENSG00000141458	-0.1379491191003638	[444,352]	[198,206]	-1	hSpCas9	negative selection	5424672
23554879	23554901	18	+	27760321	MOLM13	viability	TCGTGTTATACGGTGAAAGAGG	NPC1	ENSG00000141458	-5.13187111197462	[97,83]	[1,0]	-9	hSpCas9	negative selection	5424673
23556279	23556301	18	+	27760321	MOLM13	viability	GGGTACATCAGCTCCCGAAGGG	NPC1	ENSG00000141458	-0.3933962716933625	[563,525]	[170,287]	-3	hSpCas9	negative selection	5424674
23556464	23556486	18	-	27760321	MOLM13	viability	ACTGCGTGTTCGTCAGGCCTGG	NPC1	ENSG00000141458	0.8556016172922021	[1061,926]	[1483,611]	6	hSpCas9	negative selection	5424675
23556541	23556563	18	-	27760321	MOLM13	viability	GGCGGCTGTTCACACGCTGGGG	NPC1	ENSG00000141458	-0.26119652851308284	[1376,1169]	[516,665]	-2	hSpCas9	negative selection	5424676
23586399	23586422	18	+	27661255	K562	viability	GGAGGCGGCTCTACTTCCCCGGG	NPC1	ENSG00000141458	0.11337522269518352	[820,1007]	[843,738]	4	dCas9-KRAB	negative selection	5497189
23586395	23586418	18	-	27661255	K562	viability	GGGAAGTAGAGCCGCCTCCGGGG	NPC1	ENSG00000141458	-0.01178597949600102	[635,713]	[564,506]	0	dCas9-KRAB	negative selection	5497190
23586701	23586724	18	-	27661255	K562	viability	GCATCACGGCCAGAAACCGTTGG	NPC1	ENSG00000141458	-0.006569444769710053	[1030,863]	[825,695]	0	dCas9-KRAB	negative selection	5497191
23515929	23515952	18	-	27260156	BXPC3	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.09109996787247754	[484]	[457,536,546,635]	2	hSpCas9	negative selection	5531785
23516394	23516417	18	+	27260156	BXPC3	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-0.005754107369416506	[73]	[60,57,59,138]	0	hSpCas9	negative selection	5531786
23515862	23515885	18	-	27260156	BXPC3	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.13751233601742952	[654]	[782,687,744,797]	3	hSpCas9	negative selection	5531787
23557139	23557162	18	+	27260156	BXPC3	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.25224332563429624	[780]	[598,652,617,904]	-5	hSpCas9	negative selection	5558533
23568840	23568863	18	-	27260156	BXPC3	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.6635965561081106	[297]	[161,159,255,216]	-8	hSpCas9	negative selection	5558534
23561444	23561467	18	+	27260156	BXPC3	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.3528928551974517	[26]	[28,49,34,28]	7	hSpCas9	negative selection	5558535
23516396	23516419	18	-	27260156	BXPC3	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.4083334376976403	[873]	[1051,1182,1257,1391]	8	hSpCas9	negative selection	5596067
23561477	23561500	18	-	27260156	BXPC3	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.5575911836323248	[307]	[164,227,192,302]	-8	hSpCas9	negative selection	5622790
23557116	23557139	18	-	27260156	BXPC3	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.19822769622847491	[686]	[527,572,721,701]	-4	hSpCas9	negative selection	5622791
23568921	23568944	18	+	27260156	BXPC3	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	-0.26673920217546776	[203]	[90,173,172,293]	-6	hSpCas9	negative selection	5622792
23515929	23515952	18	-	27260156	A673	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.028557486139706906	[484]	[772,498,495,632]	0	hSpCas9	negative selection	5653036
23516394	23516417	18	+	27260156	A673	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-0.00597388772048113	[73]	[95,52,92,114]	0	hSpCas9	negative selection	5653037
23515862	23515885	18	-	27260156	A673	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.09124355610440904	[654]	[938,830,859,724]	2	hSpCas9	negative selection	5653038
23557139	23557162	18	+	27260156	A673	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.3700396696247631	[780]	[780,810,535,781]	-7	hSpCas9	negative selection	5679784
23568840	23568863	18	-	27260156	A673	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.37071827476449115	[297]	[377,266,270,197]	-7	hSpCas9	negative selection	5679785
23561444	23561467	18	+	27260156	A673	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.5622169399441983	[26]	[41,46,48,52]	9	hSpCas9	negative selection	5679786
23516396	23516419	18	-	27260156	A673	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.34179406185036865	[873]	[1531,1262,1208,1339]	7	hSpCas9	negative selection	5717318
23561477	23561500	18	-	27260156	A673	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.3057047851686866	[307]	[359,264,269,309]	-6	hSpCas9	negative selection	5744041
23557116	23557139	18	-	27260156	A673	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.07718946888648309	[686]	[882,733,775,743]	-2	hSpCas9	negative selection	5744042
23568921	23568944	18	+	27260156	A673	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.1589500825065524	[203]	[278,317,197,299]	4	hSpCas9	negative selection	5744043
23515929	23515952	18	-	27260156	A375	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.47106379692203926	[484]	[630,958,925,659]	7	hSpCas9	negative selection	5774287
23516394	23516417	18	+	27260156	A375	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.1235951824062691	[73]	[33,189,50,111]	1	hSpCas9	negative selection	5774288
23515862	23515885	18	-	27260156	A375	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.5212658507683808	[654]	[1084,1283,1191,878]	7	hSpCas9	negative selection	5774289
23557139	23557162	18	+	27260156	A375	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.31383880634346484	[780]	[631,915,719,693]	-4	hSpCas9	negative selection	5801035
23568840	23568863	18	-	27260156	A375	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-1.5847715830024987	[297]	[158,130,86,91]	-9	hSpCas9	negative selection	5801036
23561444	23561467	18	+	27260156	A375	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	-1.049652416154995	[26]	[50,8,0,0]	-8	hSpCas9	negative selection	5801037
23516396	23516419	18	-	27260156	A375	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.6517245387040217	[873]	[1662,1777,1430,1565]	8	hSpCas9	negative selection	5838569
23561477	23561500	18	-	27260156	A375	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.8883883810426461	[307]	[192,352,153,108]	-8	hSpCas9	negative selection	5865292
23557116	23557139	18	-	27260156	A375	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.5190475540633753	[686]	[549,615,654,438]	-6	hSpCas9	negative selection	5865293
23568921	23568944	18	+	27260156	A375	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	-0.11713830080883603	[203]	[391,238,161,102]	-2	hSpCas9	negative selection	5865294
23515929	23515952	18	-	27260156	COLO741	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.07216893626082893	[484]	[762,572,627]	1	hSpCas9	negative selection	5895538
23516394	23516417	18	+	27260156	COLO741	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.487095492993725	[73]	[96,187,110]	8	hSpCas9	negative selection	5895539
23515862	23515885	18	-	27260156	COLO741	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.1005835525276848	[654]	[886,944,859]	2	hSpCas9	negative selection	5895540
23557139	23557162	18	+	27260156	COLO741	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.5386148677401632	[780]	[802,620,647]	-8	hSpCas9	negative selection	5922286
23568840	23568863	18	-	27260156	COLO741	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.41891129207014666	[297]	[331,342,189]	-7	hSpCas9	negative selection	5922287
23561444	23561467	18	+	27260156	COLO741	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	1.1128635253538333	[26]	[90,86,48]	9	hSpCas9	negative selection	5922288
23516396	23516419	18	-	27260156	COLO741	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.176930139684918	[873]	[1504,1294,1022]	4	hSpCas9	negative selection	5959820
23561477	23561500	18	-	27260156	COLO741	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.38215489145691817	[307]	[317,362,230]	-7	hSpCas9	negative selection	5986543
23557116	23557139	18	-	27260156	COLO741	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.03895292567509101	[686]	[889,746,921]	-1	hSpCas9	negative selection	5986544
23568921	23568944	18	+	27260156	COLO741	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.12487351611981712	[203]	[300,373,185]	2	hSpCas9	negative selection	5986545
23515929	23515952	18	-	27260156	CAL120	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.29303242195292656	[484]	[1130,464,681]	4	hSpCas9	negative selection	6016789
23516394	23516417	18	+	27260156	CAL120	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	1.4730731383951987	[73]	[682,109,41]	9	hSpCas9	negative selection	6016790
23515862	23515885	18	-	27260156	CAL120	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.2111754133633409	[654]	[1241,623,1007]	3	hSpCas9	negative selection	6016791
23557139	23557162	18	+	27260156	CAL120	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.049282748097348006	[780]	[1049,846,936]	0	hSpCas9	negative selection	6043537
23568840	23568863	18	-	27260156	CAL120	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.14399420354733194	[297]	[334,135,531]	-2	hSpCas9	negative selection	6043538
23561444	23561467	18	+	27260156	CAL120	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	-0.5061038593538614	[26]	[36,13,21]	-6	hSpCas9	negative selection	6043539
23516396	23516419	18	-	27260156	CAL120	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.4101041820695305	[873]	[1588,1178,1585]	6	hSpCas9	negative selection	6081071
23561477	23561500	18	-	27260156	CAL120	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.30052735844665435	[307]	[294,378,257]	-4	hSpCas9	negative selection	6107794
23557116	23557139	18	-	27260156	CAL120	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.40189524346752986	[686]	[606,578,746]	-5	hSpCas9	negative selection	6107795
23568921	23568944	18	+	27260156	CAL120	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.31315090150791947	[203]	[285,360,294]	5	hSpCas9	negative selection	6107796
23515929	23515952	18	-	27260156	CADOES1	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.17408031089149167	[484]	[463,480,447,647]	3	hSpCas9	negative selection	6138040
23516394	23516417	18	+	27260156	CADOES1	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-0.4474625456825585	[73]	[79,6,56,57]	-7	hSpCas9	negative selection	6138041
23515862	23515885	18	-	27260156	CADOES1	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.19642568080326828	[654]	[773,666,497,858]	3	hSpCas9	negative selection	6138042
23557139	23557162	18	+	27260156	CADOES1	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.0941800674730916	[780]	[731,576,770,639]	-2	hSpCas9	negative selection	6164788
23568840	23568863	18	-	27260156	CADOES1	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.324834660224916	[297]	[196,397,185,99]	-5	hSpCas9	negative selection	6164789
23561444	23561467	18	+	27260156	CADOES1	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.1968183958444225	[26]	[41,31,14,25]	3	hSpCas9	negative selection	6164790
23516396	23516419	18	-	27260156	CADOES1	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.5462093333086134	[873]	[1114,1371,1164,1092]	8	hSpCas9	negative selection	6202322
23561477	23561500	18	-	27260156	CADOES1	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	0.14615775953819765	[307]	[265,471,250,277]	2	hSpCas9	negative selection	6229045
23557116	23557139	18	-	27260156	CADOES1	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.10131572900897445	[686]	[684,755,561,740]	1	hSpCas9	negative selection	6229046
23568921	23568944	18	+	27260156	CADOES1	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.11894697310419566	[203]	[209,201,183,228]	2	hSpCas9	negative selection	6229047
23515929	23515952	18	-	27260156	EWS502	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.2327070779748127	[484]	[589,522,772,527]	4	hSpCas9	negative selection	6259291
23516394	23516417	18	+	27260156	EWS502	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.5882160278701964	[73]	[108,125,144,89]	8	hSpCas9	negative selection	6259292
23515862	23515885	18	-	27260156	EWS502	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.3641017384873051	[654]	[803,671,1008,1120]	6	hSpCas9	negative selection	6259293
23557139	23557162	18	+	27260156	EWS502	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.1776692908200146	[780]	[677,777,696,776]	-3	hSpCas9	negative selection	6286039
23568840	23568863	18	-	27260156	EWS502	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.457022372630307	[297]	[206,200,262,253]	-7	hSpCas9	negative selection	6286040
23561444	23561467	18	+	27260156	EWS502	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.9025117295082361	[26]	[32,50,39,94]	9	hSpCas9	negative selection	6286041
23516396	23516419	18	-	27260156	EWS502	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.45995677841310456	[873]	[1248,1268,1394,1172]	7	hSpCas9	negative selection	6323573
23561477	23561500	18	-	27260156	EWS502	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.019636876870938513	[307]	[297,390,409,177]	0	hSpCas9	negative selection	6350296
23557116	23557139	18	-	27260156	EWS502	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.3599930411655433	[686]	[594,904,1007,1292]	6	hSpCas9	negative selection	6350297
23568921	23568944	18	+	27260156	EWS502	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.4368285340364896	[203]	[258,378,198,333]	7	hSpCas9	negative selection	6350298
23515929	23515952	18	-	27260156	EW8	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.09819543398595765	[484]	[637,308,362,404]	1	hSpCas9	negative selection	6380542
23516394	23516417	18	+	27260156	EW8	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-0.12620180072665743	[73]	[32,57,49,76]	-2	hSpCas9	negative selection	6380543
23515862	23515885	18	-	27260156	EW8	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.16394766641037228	[654]	[662,562,465,713]	3	hSpCas9	negative selection	6380544
23557139	23557162	18	+	27260156	EW8	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.20422502814251897	[780]	[565,519,516,599]	-4	hSpCas9	negative selection	6407290
23568840	23568863	18	-	27260156	EW8	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.8362952889734877	[297]	[180,88,101,178]	-9	hSpCas9	negative selection	6407291
23561444	23561467	18	+	27260156	EW8	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.2725040555013112	[26]	[61,17,11,19]	5	hSpCas9	negative selection	6407292
23516396	23516419	18	-	27260156	EW8	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.524530011531077	[873]	[1272,867,1000,960]	8	hSpCas9	negative selection	6444824
23561477	23561500	18	-	27260156	EW8	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.19550623095422626	[307]	[397,185,171,142]	-4	hSpCas9	negative selection	6471547
23557116	23557139	18	-	27260156	EW8	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.2616927560192357	[686]	[1008,499,584,624]	5	hSpCas9	negative selection	6471548
23568921	23568944	18	+	27260156	EW8	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.34073349715899437	[203]	[301,289,124,144]	6	hSpCas9	negative selection	6471549
23515929	23515952	18	-	27260156	CORL105	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.01754202833493272	[484]	[804,385,577,541]	0	hSpCas9	negative selection	6501793
23516394	23516417	18	+	27260156	CORL105	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.22357075204608945	[73]	[122,32,91,156]	4	hSpCas9	negative selection	6501794
23515862	23515885	18	-	27260156	CORL105	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	-0.02135409388136711	[654]	[841,582,868,751]	0	hSpCas9	negative selection	6501795
23557139	23557162	18	+	27260156	CORL105	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.13357356152200972	[780]	[798,705,1444,481]	-2	hSpCas9	negative selection	6528541
23568840	23568863	18	-	27260156	CORL105	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.5695041639124981	[297]	[328,296,141,159]	-7	hSpCas9	negative selection	6528542
23561444	23561467	18	+	27260156	CORL105	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	1.206617782794222	[26]	[55,109,106,22]	9	hSpCas9	negative selection	6528543
23516396	23516419	18	-	27260156	CORL105	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.4482655494286091	[873]	[1651,1205,1474,1275]	7	hSpCas9	negative selection	6566075
23561477	23561500	18	-	27260156	CORL105	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	0.044432257344967696	[307]	[340,576,309,244]	0	hSpCas9	negative selection	6592798
23557116	23557139	18	-	27260156	CORL105	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.22259819124690555	[686]	[718,595,942,541]	-4	hSpCas9	negative selection	6592799
23568921	23568944	18	+	27260156	CORL105	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.4244910703376844	[203]	[328,237,416,314]	7	hSpCas9	negative selection	6592800
23515929	23515952	18	-	27260156	HS294T	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.10363615542711921	[484]	[134,182,294,198]	1	hSpCas9	negative selection	6623044
23516394	23516417	18	+	27260156	HS294T	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-0.29247045862347143	[73]	[21,11,20,41]	-4	hSpCas9	negative selection	6623045
23515862	23515885	18	-	27260156	HS294T	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	-0.0738142540469996	[654]	[239,181,214,343]	-1	hSpCas9	negative selection	6623046
23557139	23557162	18	+	27260156	HS294T	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.22383509570675042	[780]	[246,218,260,318]	-3	hSpCas9	negative selection	6649792
23568840	23568863	18	-	27260156	HS294T	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.462157626572668	[297]	[110,44,62,119]	-6	hSpCas9	negative selection	6649793
23561444	23561467	18	+	27260156	HS294T	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	-0.08656475853296897	[26]	[7,4,9,17]	-1	hSpCas9	negative selection	6649794
23516396	23516419	18	-	27260156	HS294T	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.3288731619382449	[873]	[425,404,410,460]	4	hSpCas9	negative selection	6687326
23561477	23561500	18	-	27260156	HS294T	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.8054921065044607	[307]	[41,58,96,78]	-8	hSpCas9	negative selection	6714049
23557116	23557139	18	-	27260156	HS294T	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.026465476059044812	[686]	[229,222,270,334]	0	hSpCas9	negative selection	6714050
23568921	23568944	18	+	27260156	HS294T	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.2390078165579489	[203]	[101,58,114,96]	3	hSpCas9	negative selection	6714051
23515929	23515952	18	-	27260156	HCC44	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.20405966224932717	[484]	[597,422,1015,579]	3	hSpCas9	negative selection	6744295
23516394	23516417	18	+	27260156	HCC44	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-0.3126743098395868	[73]	[53,62,22,118]	-5	hSpCas9	negative selection	6744296
23515862	23515885	18	-	27260156	HCC44	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.22979061071047446	[654]	[892,736,869,984]	3	hSpCas9	negative selection	6744297
23557139	23557162	18	+	27260156	HCC44	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.12241775968042745	[780]	[761,946,946,589]	-2	hSpCas9	negative selection	6771043
23568840	23568863	18	-	27260156	HCC44	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.5873233322679864	[297]	[271,117,276,255]	-7	hSpCas9	negative selection	6771044
23561444	23561467	18	+	27260156	HCC44	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	1.0694195354124632	[26]	[42,35,107,77]	9	hSpCas9	negative selection	6771045
23516396	23516419	18	-	27260156	HCC44	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.3952855481216212	[873]	[1253,1251,1513,1211]	6	hSpCas9	negative selection	6808577
23561477	23561500	18	-	27260156	HCC44	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.48448284658560303	[307]	[330,110,301,284]	-6	hSpCas9	negative selection	6835300
23557116	23557139	18	-	27260156	HCC44	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.243345822566305	[686]	[733,1112,940,844]	4	hSpCas9	negative selection	6835301
23568921	23568944	18	+	27260156	HCC44	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.11904759748412475	[203]	[244,330,214,192]	1	hSpCas9	negative selection	6835302
23515929	23515952	18	-	27260156	G402	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	-0.32143472365572556	[484]	[417,587,428,456]	-4	hSpCas9	negative selection	6865546
23516394	23516417	18	+	27260156	G402	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-1.3733043856514695	[73]	[61,15,26,36]	-9	hSpCas9	negative selection	6865547
23515862	23515885	18	-	27260156	G402	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.4409533849995493	[654]	[1640,820,1222,732]	5	hSpCas9	negative selection	6865548
23557139	23557162	18	+	27260156	G402	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	0.2546936509969938	[780]	[771,1670,1114,971]	3	hSpCas9	negative selection	6892294
23568840	23568863	18	-	27260156	G402	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.421169572197415	[297]	[457,150,52,434]	-5	hSpCas9	negative selection	6892295
23561444	23561467	18	+	27260156	G402	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.23602218519535745	[26]	[68,23,14,49]	3	hSpCas9	negative selection	6892296
23516396	23516419	18	-	27260156	G402	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	1.0831249756899477	[873]	[2389,2083,2207,2350]	9	hSpCas9	negative selection	6929828
23561477	23561500	18	-	27260156	G402	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.8237664744296473	[307]	[150,231,207,247]	-7	hSpCas9	negative selection	6956551
23557116	23557139	18	-	27260156	G402	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.09450154209413059	[686]	[918,746,881,614]	-1	hSpCas9	negative selection	6956552
23568921	23568944	18	+	27260156	G402	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.8822906142100859	[203]	[637,181,641,384]	9	hSpCas9	negative selection	6956553
23515929	23515952	18	-	27260156	L33	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.22911234989777515	[484]	[527,208,368,648]	5	hSpCas9	negative selection	6986797
23516394	23516417	18	+	27260156	L33	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-0.14987247102693058	[73]	[60,35,54,30]	-3	hSpCas9	negative selection	6986798
23515862	23515885	18	-	27260156	L33	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	-0.1791556241938994	[654]	[432,212,431,676]	-4	hSpCas9	negative selection	6986799
23557139	23557162	18	+	27260156	L33	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.08685161897482974	[780]	[825,277,475,677]	-2	hSpCas9	negative selection	7013545
23568840	23568863	18	-	27260156	L33	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.6202552083527294	[297]	[174,73,156,170]	-9	hSpCas9	negative selection	7013546
23561444	23561467	18	+	27260156	L33	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.4655714135508777	[26]	[29,11,26,46]	8	hSpCas9	negative selection	7013547
23516396	23516419	18	-	27260156	L33	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.22141308410935834	[873]	[1058,467,674,801]	5	hSpCas9	negative selection	7051079
23561477	23561500	18	-	27260156	L33	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.09433363390482252	[307]	[315,122,151,294]	-2	hSpCas9	negative selection	7077802
23557116	23557139	18	-	27260156	L33	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.13610152845662182	[686]	[808,311,428,764]	3	hSpCas9	negative selection	7077803
23568921	23568944	18	+	27260156	L33	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.204638452527531	[203]	[208,71,154,308]	4	hSpCas9	negative selection	7077804
23515929	23515952	18	-	27260156	K562	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.5931882785243955	[484]	[517,564,1023,490]	7	hSpCas9	negative selection	7108048
23516394	23516417	18	+	27260156	K562	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-2.3227090185510515	[73]	[29,6,7,8]	-9	hSpCas9	negative selection	7108049
23515862	23515885	18	-	27260156	K562	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	-0.09105264495731574	[654]	[353,691,509,608]	-1	hSpCas9	negative selection	7108050
23557139	23557162	18	+	27260156	K562	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	0.2245659125684225	[780]	[1112,564,733,832]	3	hSpCas9	negative selection	7134796
23568840	23568863	18	-	27260156	K562	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-1.0889168600317785	[297]	[121,215,25,135]	-8	hSpCas9	negative selection	7134797
23561444	23561467	18	+	27260156	K562	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	-1.0757775062315584	[26]	[25,1,14,3]	-8	hSpCas9	negative selection	7134798
23516396	23516419	18	-	27260156	K562	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.5952658531172584	[873]	[839,1124,1775,938]	7	hSpCas9	negative selection	7172330
23561477	23561500	18	-	27260156	K562	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.17384462788707578	[307]	[53,284,486,140]	-2	hSpCas9	negative selection	7199053
23557116	23557139	18	-	27260156	K562	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.518852701962246	[686]	[440,393,544,330]	-6	hSpCas9	negative selection	7199054
23568921	23568944	18	+	27260156	K562	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	-0.34204663687488024	[203]	[140,148,195,90]	-4	hSpCas9	negative selection	7199055
23515929	23515952	18	-	27260156	HT29	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.20024474480065396	[484]	[575,700,728,690]	4	hSpCas9	negative selection	7229299
23516394	23516417	18	+	27260156	HT29	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.17319939206943324	[73]	[138,110,86,74]	3	hSpCas9	negative selection	7229300
23515862	23515885	18	-	27260156	HT29	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.25991210365329487	[654]	[784,1110,1161,771]	5	hSpCas9	negative selection	7229301
23557139	23557162	18	+	27260156	HT29	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.39229449826638524	[780]	[804,783,787,544]	-6	hSpCas9	negative selection	7256047
23568840	23568863	18	-	27260156	HT29	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.2501081792369656	[297]	[262,284,418,250]	-5	hSpCas9	negative selection	7256048
23561444	23561467	18	+	27260156	HT29	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.8495613082203692	[26]	[98,54,53,33]	9	hSpCas9	negative selection	7256049
23516396	23516419	18	-	27260156	HT29	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.4206060741438694	[873]	[1474,1426,1614,1193]	7	hSpCas9	negative selection	7293581
23561477	23561500	18	-	27260156	HT29	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.3469327221229157	[307]	[259,290,358,265]	-6	hSpCas9	negative selection	7320304
23557116	23557139	18	-	27260156	HT29	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.12908824738982583	[686]	[796,741,659,840]	-3	hSpCas9	negative selection	7320305
23568921	23568944	18	+	27260156	HT29	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.5444870872609744	[203]	[242,479,430,298]	9	hSpCas9	negative selection	7320306
23515929	23515952	18	-	27260156	MHHES1	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.011837371663572085	[484]	[576,503,634,487]	0	hSpCas9	negative selection	7350550
23516394	23516417	18	+	27260156	MHHES1	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.22086247410567017	[73]	[43,190,96,64]	4	hSpCas9	negative selection	7350551
23515862	23515885	18	-	27260156	MHHES1	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.20150188313553563	[654]	[1087,815,1066,509]	3	hSpCas9	negative selection	7350552
23557139	23557162	18	+	27260156	MHHES1	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.06449233703480739	[780]	[1265,669,820,663]	-1	hSpCas9	negative selection	7377298
23568840	23568863	18	-	27260156	MHHES1	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.24099797558189007	[297]	[289,217,216,375]	-4	hSpCas9	negative selection	7377299
23561444	23561467	18	+	27260156	MHHES1	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.800945685945027	[26]	[52,99,63,8]	9	hSpCas9	negative selection	7377300
23516396	23516419	18	-	27260156	MHHES1	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.5766034135684986	[873]	[1407,1813,1357,1319]	8	hSpCas9	negative selection	7414832
23561477	23561500	18	-	27260156	MHHES1	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.35885167494115056	[307]	[250,299,278,250]	-6	hSpCas9	negative selection	7441555
23557116	23557139	18	-	27260156	MHHES1	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.2648153072734438	[686]	[1220,1031,850,693]	5	hSpCas9	negative selection	7441556
23568921	23568944	18	+	27260156	MHHES1	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	-0.2166345809389838	[203]	[280,263,169,108]	-4	hSpCas9	negative selection	7441557
23515929	23515952	18	-	27260156	MEWO	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.2145862067427511	[484]	[592,589,408]	5	hSpCas9	negative selection	7471801
23516394	23516417	18	+	27260156	MEWO	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	1.0633344151834125	[73]	[205,119,119]	9	hSpCas9	negative selection	7471802
23515862	23515885	18	-	27260156	MEWO	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.34380037208584635	[654]	[715,767,836]	7	hSpCas9	negative selection	7471803
23557139	23557162	18	+	27260156	MEWO	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.1333892134629182	[780]	[752,689,571]	-3	hSpCas9	negative selection	7498549
23568840	23568863	18	-	27260156	MEWO	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.4225847037084035	[297]	[350,141,158]	-7	hSpCas9	negative selection	7498550
23561444	23561467	18	+	27260156	MEWO	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.4152971386973121	[26]	[53,30,19]	8	hSpCas9	negative selection	7498551
23516396	23516419	18	-	27260156	MEWO	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.21591841438034243	[873]	[1178,802,911]	5	hSpCas9	negative selection	7536083
23561477	23561500	18	-	27260156	MEWO	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	0.06513656460707173	[307]	[247,292,352]	1	hSpCas9	negative selection	7562806
23557116	23557139	18	-	27260156	MEWO	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.027649697823041275	[686]	[843,590,497]	0	hSpCas9	negative selection	7562807
23568921	23568944	18	+	27260156	MEWO	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.1673293003583065	[203]	[177,191,265]	3	hSpCas9	negative selection	7562808
23515929	23515952	18	-	27260156	LNCAPCLONEFGC	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.24291313748186508	[484]	[654,342,584,514]	4	hSpCas9	negative selection	7593052
23516394	23516417	18	+	27260156	LNCAPCLONEFGC	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.17954576469414274	[73]	[37,138,40,76]	3	hSpCas9	negative selection	7593053
23515862	23515885	18	-	27260156	LNCAPCLONEFGC	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.2281958493791736	[654]	[642,618,892,659]	3	hSpCas9	negative selection	7593054
23557139	23557162	18	+	27260156	LNCAPCLONEFGC	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.2839565365313654	[780]	[569,457,666,649]	-4	hSpCas9	negative selection	7619800
23568840	23568863	18	-	27260156	LNCAPCLONEFGC	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.743362116065953	[297]	[105,230,77,213]	-8	hSpCas9	negative selection	7619801
23561444	23561467	18	+	27260156	LNCAPCLONEFGC	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.9035947739265682	[26]	[43,30,65,45]	9	hSpCas9	negative selection	7619802
23516396	23516419	18	-	27260156	LNCAPCLONEFGC	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.6802745329035867	[873]	[1150,1395,1256,1261]	9	hSpCas9	negative selection	7657334
23561477	23561500	18	-	27260156	LNCAPCLONEFGC	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.6275184964715492	[307]	[118,149,237,226]	-7	hSpCas9	negative selection	7684057
23557116	23557139	18	-	27260156	LNCAPCLONEFGC	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.3431751860642722	[686]	[368,448,590,572]	-5	hSpCas9	negative selection	7684058
23568921	23568944	18	+	27260156	LNCAPCLONEFGC	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	-0.6582729626377422	[203]	[49,124,183,119]	-7	hSpCas9	negative selection	7684059
23515929	23515952	18	-	27260156	PANC0327	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.22445540345540735	[484]	[564,422,643,396]	3	hSpCas9	negative selection	7714303
23516394	23516417	18	+	27260156	PANC0327	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-1.545962300501055	[73]	[28,26,21,11]	-9	hSpCas9	negative selection	7714304
23515862	23515885	18	-	27260156	PANC0327	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	-0.1408479848189122	[654]	[877,367,457,455]	-2	hSpCas9	negative selection	7714305
23557139	23557162	18	+	27260156	PANC0327	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.0434315231427459	[780]	[938,538,776,476]	0	hSpCas9	negative selection	7741051
23568840	23568863	18	-	27260156	PANC0327	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-1.0901795726387915	[297]	[162,49,103,192]	-8	hSpCas9	negative selection	7741052
23561444	23561467	18	+	27260156	PANC0327	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.07176749603940635	[26]	[17,11,57,13]	1	hSpCas9	negative selection	7741053
23516396	23516419	18	-	27260156	PANC0327	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.35214220842390265	[873]	[981,873,975,1145]	5	hSpCas9	negative selection	7778585
23561477	23561500	18	-	27260156	PANC0327	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.5288155360758171	[307]	[155,273,236,77]	-6	hSpCas9	negative selection	7805308
23557116	23557139	18	-	27260156	PANC0327	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.44133429954668923	[686]	[703,336,424,366]	-6	hSpCas9	negative selection	7805309
23568921	23568944	18	+	27260156	PANC0327	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	-0.25595014726881815	[203]	[156,94,280,81]	-4	hSpCas9	negative selection	7805310
23515929	23515952	18	-	27260156	NCIH2009	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.06191058668673963	[484]	[688,771,654]	0	hSpCas9	negative selection	7835554
23516394	23516417	18	+	27260156	NCIH2009	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.8924401921173946	[73]	[231,156,194]	9	hSpCas9	negative selection	7835555
23515862	23515885	18	-	27260156	NCIH2009	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.10932161626800219	[654]	[1012,929,1022]	1	hSpCas9	negative selection	7835556
23557139	23557162	18	+	27260156	NCIH2009	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.04151190617442635	[780]	[1078,982,1121]	0	hSpCas9	negative selection	7862302
23568840	23568863	18	-	27260156	NCIH2009	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.9087282793918999	[297]	[291,266,118]	-8	hSpCas9	negative selection	7862303
23561444	23561467	18	+	27260156	NCIH2009	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.32240731166487757	[26]	[53,34,53]	4	hSpCas9	negative selection	7862304
23516396	23516419	18	-	27260156	NCIH2009	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.49315364594955124	[873]	[1553,1924,1637]	6	hSpCas9	negative selection	7899836
23561477	23561500	18	-	27260156	NCIH2009	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.20999141663297072	[307]	[305,394,400]	-3	hSpCas9	negative selection	7926559
23557116	23557139	18	-	27260156	NCIH2009	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.3701279564566108	[686]	[925,572,766]	-5	hSpCas9	negative selection	7926560
23568921	23568944	18	+	27260156	NCIH2009	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.1844577039149049	[203]	[278,282,400]	2	hSpCas9	negative selection	7926561
23515929	23515952	18	-	27260156	NCIH1373	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.30759183909501675	[484]	[1202,611,460,129]	3	hSpCas9	negative selection	7956805
23516394	23516417	18	+	27260156	NCIH1373	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-0.054578713617953856	[73]	[31,65,168,10]	0	hSpCas9	negative selection	7956806
23515862	23515885	18	-	27260156	NCIH1373	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.533972268412871	[654]	[1370,645,1305,264]	5	hSpCas9	negative selection	7956807
23557139	23557162	18	+	27260156	NCIH1373	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	0.5756263964135181	[780]	[1749,958,1475,293]	5	hSpCas9	negative selection	7983553
23568840	23568863	18	-	27260156	NCIH1373	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.8847018734559889	[297]	[193,115,223,51]	-7	hSpCas9	negative selection	7983554
23561444	23561467	18	+	27260156	NCIH1373	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	-0.2407667185022655	[26]	[3,13,40,10]	-2	hSpCas9	negative selection	7983555
23516396	23516419	18	-	27260156	NCIH1373	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	1.2243040781386685	[873]	[1751,2893,2368,513]	9	hSpCas9	negative selection	8021087
23561477	23561500	18	-	27260156	NCIH1373	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.4604166582188862	[307]	[236,264,178,84]	-4	hSpCas9	negative selection	8047810
23557116	23557139	18	-	27260156	NCIH1373	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.0703542369322856	[686]	[722,755,645,211]	0	hSpCas9	negative selection	8047811
23568921	23568944	18	+	27260156	NCIH1373	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	1.055599510347634	[203]	[652,217,534,144]	9	hSpCas9	negative selection	8047812
23515929	23515952	18	-	27260156	PATU8902	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.20850554245033312	[484]	[573,813,521,1342]	2	hSpCas9	negative selection	8078056
23516394	23516417	18	+	27260156	PATU8902	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.0774461794120942	[73]	[80,109,66,197]	0	hSpCas9	negative selection	8078057
23515862	23515885	18	-	27260156	PATU8902	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.43906730122045357	[654]	[949,1601,889,1637]	4	hSpCas9	negative selection	8078058
23557139	23557162	18	+	27260156	PATU8902	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	0.35585165035342226	[780]	[1781,792,831,2409]	3	hSpCas9	negative selection	8104804
23568840	23568863	18	-	27260156	PATU8902	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.05283200757912909	[297]	[553,178,220,725]	0	hSpCas9	negative selection	8104805
23561444	23561467	18	+	27260156	PATU8902	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	2.261166361473758	[26]	[31,337,128,243]	9	hSpCas9	negative selection	8104806
23516396	23516419	18	-	27260156	PATU8902	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.7281784984352523	[873]	[1768,2262,1660,2511]	7	hSpCas9	negative selection	8142338
23561477	23561500	18	-	27260156	PATU8902	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	0.55237361306152	[307]	[325,768,574,890]	6	hSpCas9	negative selection	8169061
23557116	23557139	18	-	27260156	PATU8902	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.43641459601446086	[686]	[1527,1236,1047,1432]	4	hSpCas9	negative selection	8169062
23568921	23568944	18	+	27260156	PATU8902	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.35955262469331883	[203]	[172,370,428,481]	3	hSpCas9	negative selection	8169063
23515929	23515952	18	-	27260156	PANC1	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	-0.10165665994299619	[484]	[369,452,455,296]	-2	hSpCas9	negative selection	8199307
23516394	23516417	18	+	27260156	PANC1	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-0.9958289654471226	[73]	[23,34,24,41]	-8	hSpCas9	negative selection	8199308
23515862	23515885	18	-	27260156	PANC1	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.36781583330607315	[654]	[546,849,754,762]	6	hSpCas9	negative selection	8199309
23557139	23557162	18	+	27260156	PANC1	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.11122092632007807	[780]	[510,820,644,551]	-2	hSpCas9	negative selection	8226055
23568840	23568863	18	-	27260156	PANC1	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.3583798637152714	[297]	[228,318,155,126]	-5	hSpCas9	negative selection	8226056
23561444	23561467	18	+	27260156	PANC1	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.7597280532538866	[26]	[20,53,52,32]	9	hSpCas9	negative selection	8226057
23516396	23516419	18	-	27260156	PANC1	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.49676410146479066	[873]	[996,1488,1247,645]	7	hSpCas9	negative selection	8263589
23561477	23561500	18	-	27260156	PANC1	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.40483280878662	[307]	[241,297,152,132]	-6	hSpCas9	negative selection	8290312
23557116	23557139	18	-	27260156	PANC1	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.1993898877268206	[686]	[550,723,486,353]	-3	hSpCas9	negative selection	8290313
23568921	23568944	18	+	27260156	PANC1	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	-0.17284994006113363	[203]	[135,302,179,48]	-3	hSpCas9	negative selection	8290314
23515929	23515952	18	-	27260156	PANC0813	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	-0.43042154766429075	[484]	[448,441,301,494]	-6	hSpCas9	negative selection	8320558
23516394	23516417	18	+	27260156	PANC0813	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	1.0235783375588912	[73]	[209,111,110,270]	9	hSpCas9	negative selection	8320559
23515862	23515885	18	-	27260156	PANC0813	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.01817354916828895	[654]	[768,743,846,755]	0	hSpCas9	negative selection	8320560
23557139	23557162	18	+	27260156	PANC0813	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.258405726596311	[780]	[1072,743,670,614]	-4	hSpCas9	negative selection	8347306
23568840	23568863	18	-	27260156	PANC0813	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.831714777369749	[297]	[184,234,148,214]	-8	hSpCas9	negative selection	8347307
23561444	23561467	18	+	27260156	PANC0813	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	-0.2153777774879746	[26]	[44,14,8,40]	-3	hSpCas9	negative selection	8347308
23516396	23516419	18	-	27260156	PANC0813	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.29807728616771956	[873]	[1664,1092,1160,1169]	5	hSpCas9	negative selection	8384840
23561477	23561500	18	-	27260156	PANC0813	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.7488620695934822	[307]	[207,103,405,146]	-8	hSpCas9	negative selection	8411563
23557116	23557139	18	-	27260156	PANC0813	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.5963077087113802	[686]	[564,516,554,501]	-7	hSpCas9	negative selection	8411564
23568921	23568944	18	+	27260156	PANC0813	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	-0.01332433251746501	[203]	[242,252,289,167]	0	hSpCas9	negative selection	8411565
23515929	23515952	18	-	27260156	RDES	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.3681569273933206	[484]	[526,664,820,928]	6	hSpCas9	negative selection	8441809
23516394	23516417	18	+	27260156	RDES	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.060627611843286466	[73]	[51,118,133,47]	1	hSpCas9	negative selection	8441810
23515862	23515885	18	-	27260156	RDES	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.2704104141649757	[654]	[683,724,961,1377]	4	hSpCas9	negative selection	8441811
23557139	23557162	18	+	27260156	RDES	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.3264662507046318	[780]	[537,638,770,985]	-5	hSpCas9	negative selection	8468557
23568840	23568863	18	-	27260156	RDES	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.2765539920958574	[297]	[281,261,207,384]	-5	hSpCas9	negative selection	8468558
23561444	23561467	18	+	27260156	RDES	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.4712735695546795	[26]	[46,33,59,27]	7	hSpCas9	negative selection	8468559
23516396	23516419	18	-	27260156	RDES	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.6145554944782702	[873]	[1308,1394,1817,1681]	8	hSpCas9	negative selection	8506091
23561477	23561500	18	-	27260156	RDES	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.21383120292703395	[307]	[266,266,337,361]	-4	hSpCas9	negative selection	8532814
23557116	23557139	18	-	27260156	RDES	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.13989964681126849	[686]	[546,644,739,1003]	-2	hSpCas9	negative selection	8532815
23568921	23568944	18	+	27260156	RDES	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.23783293865822375	[203]	[212,325,295,271]	4	hSpCas9	negative selection	8532816
23515929	23515952	18	-	27260156	PC3	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	-0.09909843372759337	[484]	[276,421,759,503]	-2	hSpCas9	negative selection	8563060
23516394	23516417	18	+	27260156	PC3	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.9576578093348038	[73]	[70,78,517,72]	9	hSpCas9	negative selection	8563061
23515862	23515885	18	-	27260156	PC3	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.03596358471806671	[654]	[452,492,1294,718]	0	hSpCas9	negative selection	8563062
23557139	23557162	18	+	27260156	PC3	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.23264200943655233	[780]	[348,653,1249,710]	-5	hSpCas9	negative selection	8589808
23568840	23568863	18	-	27260156	PC3	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.5009629728248776	[297]	[91,246,267,292]	-8	hSpCas9	negative selection	8589809
23561444	23561467	18	+	27260156	PC3	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	1.5737016541102857	[26]	[104,43,36,93]	9	hSpCas9	negative selection	8589810
23516396	23516419	18	-	27260156	PC3	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.18665116597665354	[873]	[713,804,1887,929]	4	hSpCas9	negative selection	8627342
23561477	23561500	18	-	27260156	PC3	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.47907249966829135	[307]	[186,200,409,140]	-8	hSpCas9	negative selection	8654065
23557116	23557139	18	-	27260156	PC3	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.0064839313448636915	[686]	[409,603,1366,698]	0	hSpCas9	negative selection	8654066
23568921	23568944	18	+	27260156	PC3	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.16530266829849838	[203]	[137,187,485,220]	3	hSpCas9	negative selection	8654067
23515929	23515952	18	-	27260156	PATU8988T	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.12630534715391475	[484]	[347,557,520,632]	2	hSpCas9	negative selection	8684311
23516394	23516417	18	+	27260156	PATU8988T	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	-0.7890146117507757	[73]	[39,62,40,21]	-8	hSpCas9	negative selection	8684312
23515862	23515885	18	-	27260156	PATU8988T	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.39952160932271963	[654]	[702,962,997,671]	6	hSpCas9	negative selection	8684313
23557139	23557162	18	+	27260156	PATU8988T	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	0.1555744670751802	[780]	[852,730,1041,712]	2	hSpCas9	negative selection	8711059
23568840	23568863	18	-	27260156	PATU8988T	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	1.0988966650748204	[297]	[778,537,437,714]	9	hSpCas9	negative selection	8711060
23561444	23561467	18	+	27260156	PATU8988T	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	2.204088497202397	[26]	[62,77,268,59]	9	hSpCas9	negative selection	8711061
23516396	23516419	18	-	27260156	PATU8988T	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.6664203123591824	[873]	[1004,1520,1234,1642]	9	hSpCas9	negative selection	8748593
23561477	23561500	18	-	27260156	PATU8988T	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	1.7187320148377316	[307]	[1379,555,609,1368]	9	hSpCas9	negative selection	8775316
23557116	23557139	18	-	27260156	PATU8988T	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	1.2618578653410646	[686]	[1548,1356,1999,1419]	9	hSpCas9	negative selection	8775317
23568921	23568944	18	+	27260156	PATU8988T	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.48757891634075956	[203]	[347,192,266,290]	7	hSpCas9	negative selection	8775318
23515929	23515952	18	-	27260156	T47D	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.40009113710373223	[484]	[667,882,611,810]	8	hSpCas9	negative selection	8805562
23516394	23516417	18	+	27260156	T47D	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.0008753116368440672	[73]	[57,75,87,124]	0	hSpCas9	negative selection	8805563
23515862	23515885	18	-	27260156	T47D	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.21190940132895864	[654]	[865,924,808,933]	4	hSpCas9	negative selection	8805564
23557139	23557162	18	+	27260156	T47D	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.12040570642027681	[780]	[890,877,818,753]	-3	hSpCas9	negative selection	8832310
23568840	23568863	18	-	27260156	T47D	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.4976897842847813	[297]	[302,256,233,186]	-8	hSpCas9	negative selection	8832311
23561444	23561467	18	+	27260156	T47D	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.5441443759373659	[26]	[60,44,27,49]	9	hSpCas9	negative selection	8832312
23516396	23516419	18	-	27260156	T47D	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.4330710124334546	[873]	[1357,1383,1425,1326]	8	hSpCas9	negative selection	8869844
23561477	23561500	18	-	27260156	T47D	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.06150226128747405	[307]	[309,399,288,372]	-1	hSpCas9	negative selection	8896567
23557116	23557139	18	-	27260156	T47D	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.021965342273095434	[686]	[768,732,837,919]	0	hSpCas9	negative selection	8896568
23568921	23568944	18	+	27260156	T47D	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.22800219196916338	[203]	[295,278,251,286]	5	hSpCas9	negative selection	8896569
23515929	23515952	18	-	27260156	SU8686	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.27444173791050697	[484]	[554,533,547,714]	4	hSpCas9	negative selection	8926813
23516394	23516417	18	+	27260156	SU8686	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.7853982177785765	[73]	[115,136,153,92]	9	hSpCas9	negative selection	8926814
23515862	23515885	18	-	27260156	SU8686	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.14135766640018343	[654]	[711,600,667,926]	2	hSpCas9	negative selection	8926815
23557139	23557162	18	+	27260156	SU8686	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	0.09026043319011157	[780]	[570,805,842,1156]	1	hSpCas9	negative selection	8953561
23568840	23568863	18	-	27260156	SU8686	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.10571510267301398	[297]	[248,258,247,357]	-2	hSpCas9	negative selection	8953562
23561444	23561467	18	+	27260156	SU8686	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.9812440676111023	[26]	[28,66,26,94]	9	hSpCas9	negative selection	8953563
23516396	23516419	18	-	27260156	SU8686	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.4228560917976224	[873]	[1013,1184,1078,1411]	7	hSpCas9	negative selection	8991095
23561477	23561500	18	-	27260156	SU8686	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.21729666018399152	[307]	[257,208,222,384]	-4	hSpCas9	negative selection	9017818
23557116	23557139	18	-	27260156	SU8686	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.17245838172624595	[686]	[544,692,1017,866]	3	hSpCas9	negative selection	9017819
23568921	23568944	18	+	27260156	SU8686	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.28158872745187735	[203]	[223,176,279,325]	5	hSpCas9	negative selection	9017820
23515929	23515952	18	-	27260156	SKES1	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.14352424276897768	[484]	[569,630,475,478]	3	hSpCas9	negative selection	9048064
23516394	23516417	18	+	27260156	SKES1	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.06494577338872443	[73]	[110,63,75,61]	1	hSpCas9	negative selection	9048065
23515862	23515885	18	-	27260156	SKES1	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.18492742868712542	[654]	[1068,787,489,677]	4	hSpCas9	negative selection	9048066
23557139	23557162	18	+	27260156	SKES1	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.5400977242422814	[780]	[529,434,535,613]	-8	hSpCas9	negative selection	9074812
23568840	23568863	18	-	27260156	SKES1	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.4561342593012515	[297]	[243,230,225,173]	-7	hSpCas9	negative selection	9074813
23561444	23561467	18	+	27260156	SKES1	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.9307240156964176	[26]	[114,56,31,14]	9	hSpCas9	negative selection	9074814
23516396	23516419	18	-	27260156	SKES1	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.21082326545286645	[873]	[1139,942,939,1012]	4	hSpCas9	negative selection	9112346
23561477	23561500	18	-	27260156	SKES1	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	0.03562685154945855	[307]	[374,176,367,325]	0	hSpCas9	negative selection	9139069
23557116	23557139	18	-	27260156	SKES1	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	-0.0015866396035161268	[686]	[887,686,669,532]	0	hSpCas9	negative selection	9139070
23568921	23568944	18	+	27260156	SKES1	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	-0.05797071696545353	[203]	[190,211,178,198]	-1	hSpCas9	negative selection	9139071
23515929	23515952	18	-	27260156	TOV112D	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.11080729654146634	[484]	[561,820,469,325]	2	hSpCas9	negative selection	9169315
23516394	23516417	18	+	27260156	TOV112D	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.9557231423632475	[73]	[197,69,142,149]	9	hSpCas9	negative selection	9169316
23515862	23515885	18	-	27260156	TOV112D	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.29277431832757506	[654]	[716,1013,845,683]	5	hSpCas9	negative selection	9169317
23557139	23557162	18	+	27260156	TOV112D	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.4986532734988677	[780]	[697,792,397,399]	-7	hSpCas9	negative selection	9196063
23568840	23568863	18	-	27260156	TOV112D	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.6166520697727317	[297]	[104,238,291,146]	-8	hSpCas9	negative selection	9196064
23561444	23561467	18	+	27260156	TOV112D	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.6642755472924682	[26]	[48,51,25,46]	9	hSpCas9	negative selection	9196065
23516396	23516419	18	-	27260156	TOV112D	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.3228259638342704	[873]	[979,1494,1132,864]	6	hSpCas9	negative selection	9233597
23561477	23561500	18	-	27260156	TOV112D	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.2819224704404242	[307]	[204,324,283,214]	-5	hSpCas9	negative selection	9260320
23557116	23557139	18	-	27260156	TOV112D	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.05768868806237504	[686]	[677,992,675,584]	1	hSpCas9	negative selection	9260321
23568921	23568944	18	+	27260156	TOV112D	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	-0.3487835198060085	[203]	[64,236,142,205]	-6	hSpCas9	negative selection	9260322
23515929	23515952	18	-	27260156	TC71	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	-0.12168547255549783	[484]	[466,391,466,592]	-3	hSpCas9	negative selection	9290566
23516394	23516417	18	+	27260156	TC71	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.25027154959435105	[73]	[114,90,91,77]	6	hSpCas9	negative selection	9290567
23515862	23515885	18	-	27260156	TC71	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.2546685610634152	[654]	[845,912,826,759]	6	hSpCas9	negative selection	9290568
23557139	23557162	18	+	27260156	TC71	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.3333212984572446	[780]	[622,722,621,693]	-7	hSpCas9	negative selection	9317314
23568840	23568863	18	-	27260156	TC71	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.22753035786339804	[297]	[335,280,263,204]	-6	hSpCas9	negative selection	9317315
23561444	23561467	18	+	27260156	TC71	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.8791553997739827	[26]	[65,60,55,27]	9	hSpCas9	negative selection	9317316
23516396	23516419	18	-	27260156	TC71	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.23238932435255422	[873]	[1063,1040,986,1328]	6	hSpCas9	negative selection	9354848
23561477	23561500	18	-	27260156	TC71	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.07689346699597355	[307]	[378,229,318,322]	-2	hSpCas9	negative selection	9381571
23557116	23557139	18	-	27260156	TC71	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.048005373493258396	[686]	[741,816,754,729]	1	hSpCas9	negative selection	9381572
23568921	23568944	18	+	27260156	TC71	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.0656342472415381	[203]	[202,266,210,235]	1	hSpCas9	negative selection	9381573
23515929	23515952	18	-	27260156	TC32	viability	CAGCAAGATCACGGCGCTCTCGG	NPC1	ENSG00000141458	0.36037759463776686	[484]	[599,279,756,828]	6	hSpCas9	negative selection	9411817
23516394	23516417	18	+	27260156	TC32	viability	TTCCGAAAGAGACATCGCAATGG	NPC1	ENSG00000141458	0.17039173205706604	[73]	[49,59,147,72]	3	hSpCas9	negative selection	9411818
23515862	23515885	18	-	27260156	TC32	viability	AGTTTCAGACTCCGTTTCTCTGG	NPC1	ENSG00000141458	0.3622468308051404	[654]	[621,760,1041,764]	6	hSpCas9	negative selection	9411819
23557139	23557162	18	+	27260156	TC32	viability	AAAAGCTATATTGCTATCGATGG	NPC1	ENSG00000141458	-0.16296675948356043	[780]	[634,501,889,656]	-3	hSpCas9	negative selection	9438565
23568840	23568863	18	-	27260156	TC32	viability	AAAGAGTTACAATACTACGTCGG	NPC1	ENSG00000141458	-0.4088684171963123	[297]	[234,115,354,181]	-6	hSpCas9	negative selection	9438566
23561444	23561467	18	+	27260156	TC32	viability	CGTCAGCGTCCTTCCCACACAGG	NPC1	ENSG00000141458	0.6640363046147977	[26]	[9,52,63,33]	9	hSpCas9	negative selection	9438567
23516396	23516419	18	-	27260156	TC32	viability	AGCCATTGCGATGTCTCTTTCGG	NPC1	ENSG00000141458	0.39922456791592953	[873]	[1050,764,1366,1269]	7	hSpCas9	negative selection	9476099
23561477	23561500	18	-	27260156	TC32	viability	GGCCCCCTCAAGTAATGACAAGG	NPC1	ENSG00000141458	-0.007628409363761746	[307]	[283,220,354,312]	0	hSpCas9	negative selection	9502822
23557116	23557139	18	-	27260156	TC32	viability	TCTGTTAATGCAAGTGACAAAGG	NPC1	ENSG00000141458	0.0938395795302902	[686]	[832,439,902,648]	1	hSpCas9	negative selection	9502823
23568921	23568944	18	+	27260156	TC32	viability	TTCAAAAACTGACTCTGTCGAGG	NPC1	ENSG00000141458	0.40965461984611906	[203]	[181,280,303,241]	7	hSpCas9	negative selection	9502824
23551665	23551688	18	+	27869803	HPAFII	viability after 27 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	-0.3442627869419952	[910]	[523,254,NaN]	-3	hSpCas9	negative selection	9564237
23554880	23554903	18	+	27869803	HPAFII	viability after 27 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	-2.018069448912171	[546]	[88,55,NaN]	-8	hSpCas9	negative selection	9564238
23556277	23556300	18	+	27869803	HPAFII	viability after 27 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-0.8604739117229645	[107]	[27,33,NaN]	-6	hSpCas9	negative selection	9564239
23560324	23560347	18	+	27869803	HPAFII	viability after 27 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.5318511642615937	[113]	[59,25,NaN]	-4	hSpCas9	negative selection	9564240
23561454	23561477	18	+	27869803	HPAFII	viability after 27 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-0.5390466656657977	[200]	[123,29,NaN]	-4	hSpCas9	negative selection	9564241
23586289	23586312	18	+	27869803	HPAFII	viability after 27 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	0.927580454375704	[0]	[0,0,NaN]	7	hSpCas9	negative selection	9564242
23551665	23551688	18	+	27869803	HPAFII	viability after 15 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	-0.31598829473337364	[910]	[1079,603,NaN]	-4	hSpCas9	negative selection	9646686
23554880	23554903	18	+	27869803	HPAFII	viability after 15 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	-1.1532981872120298	[546]	[341,215,NaN]	-8	hSpCas9	negative selection	9646687
23556277	23556300	18	+	27869803	HPAFII	viability after 15 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-2.220726530016166	[107]	[35,17,NaN]	-9	hSpCas9	negative selection	9646688
23560324	23560347	18	+	27869803	HPAFII	viability after 15 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-1.91159753930848	[113]	[18,40,NaN]	-9	hSpCas9	negative selection	9646689
23561454	23561477	18	+	27869803	HPAFII	viability after 15 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-0.3302587532825255	[200]	[222,139,NaN]	-4	hSpCas9	negative selection	9646690
23586289	23586312	18	+	27869803	HPAFII	viability after 15 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	-0.10397428375416773	[0]	[0,0,NaN]	-1	hSpCas9	negative selection	9646691
23551665	23551688	18	+	27869803	ASPC1	viability after 36 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	-0.12723520969623348	[1875]	[582,863,394]	-1	hSpCas9	negative selection	9729135
23554880	23554903	18	+	27869803	ASPC1	viability after 36 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	-1.1697571475214685	[1352]	[289,192,164]	-8	hSpCas9	negative selection	9729136
23556277	23556300	18	+	27869803	ASPC1	viability after 36 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-0.7364189730025037	[167]	[4,38,52]	-6	hSpCas9	negative selection	9729137
23560324	23560347	18	+	27869803	ASPC1	viability after 36 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.17847965164955903	[264]	[55,92,89]	-2	hSpCas9	negative selection	9729138
23561454	23561477	18	+	27869803	ASPC1	viability after 36 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	0.07977521753897482	[427]	[22,158,249]	0	hSpCas9	negative selection	9729139
23586289	23586312	18	+	27869803	ASPC1	viability after 36 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	-1.1070730883963507	[416]	[96,53,56]	-8	hSpCas9	negative selection	9729140
23551665	23551688	18	+	27869803	PATU8988S	viability after 35 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	-1.384170533046535	[1791]	[276,275,NaN]	-8	hSpCas9	negative selection	9811584
23554880	23554903	18	+	27869803	PATU8988S	viability after 35 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	-1.3522921874123557	[1219]	[169,214,NaN]	-8	hSpCas9	negative selection	9811585
23556277	23556300	18	+	27869803	PATU8988S	viability after 35 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-2.1486674227935545	[197]	[10,24,NaN]	-9	hSpCas9	negative selection	9811586
23560324	23560347	18	+	27869803	PATU8988S	viability after 35 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.9539749103268302	[218]	[58,31,NaN]	-7	hSpCas9	negative selection	9811587
23561454	23561477	18	+	27869803	PATU8988S	viability after 35 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-1.8290393566194458	[273]	[56,4,NaN]	-8	hSpCas9	negative selection	9811588
23586289	23586312	18	+	27869803	PATU8988S	viability after 35 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	-0.81761939756625	[375]	[50,120,NaN]	-7	hSpCas9	negative selection	9811589
23551665	23551688	18	+	27869803	PATU8988S	viability after 31 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	-0.7241687918786834	[1791]	[377,501,NaN]	-6	hSpCas9	negative selection	9894033
23554880	23554903	18	+	27869803	PATU8988S	viability after 31 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	-1.3787615624990353	[1219]	[139,246,NaN]	-8	hSpCas9	negative selection	9894034
23556277	23556300	18	+	27869803	PATU8988S	viability after 31 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-2.373278756521004	[197]	[5,26,NaN]	-9	hSpCas9	negative selection	9894035
23560324	23560347	18	+	27869803	PATU8988S	viability after 31 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-0.7724988173990537	[218]	[51,49,NaN]	-7	hSpCas9	negative selection	9894036
23561454	23561477	18	+	27869803	PATU8988S	viability after 31 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-2.086685102359653	[273]	[30,18,NaN]	-9	hSpCas9	negative selection	9894037
23586289	23586312	18	+	27869803	PATU8988S	viability after 31 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	-0.8020471167458845	[375]	[30,155,NaN]	-7	hSpCas9	negative selection	9894038
23551665	23551688	18	+	27869803	HPAFII	viability after 35 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	-1.6921014656636837	[910]	[185,93,NaN]	-7	hSpCas9	negative selection	9976482
23554880	23554903	18	+	27869803	HPAFII	viability after 35 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	-2.726841013706574	[546]	[54,26,NaN]	-8	hSpCas9	negative selection	9976483
23556277	23556300	18	+	27869803	HPAFII	viability after 35 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-1.1988075662666406	[107]	[12,35,NaN]	-6	hSpCas9	negative selection	9976484
23560324	23560347	18	+	27869803	HPAFII	viability after 35 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-1.7727614341812648	[113]	[30,0,NaN]	-7	hSpCas9	negative selection	9976485
23561454	23561477	18	+	27869803	HPAFII	viability after 35 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-0.26595953760369184	[200]	[157,1,NaN]	-2	hSpCas9	negative selection	9976486
23586289	23586312	18	+	27869803	HPAFII	viability after 35 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	0.9820885529966752	[0]	[0,0,NaN]	6	hSpCas9	negative selection	9976487
23551665	23551688	18	+	27869803	HPAFII	viability after 31 days	CCACCAAACGTACCCAGACAAGG	NPC1	ENSG00000141458	-1.1276594038523624	[910]	[322,136,NaN]	-6	hSpCas9	negative selection	10058931
23554880	23554903	18	+	27869803	HPAFII	viability after 31 days	CGTGTTATACGGTGAAAGAGGGG	NPC1	ENSG00000141458	-2.1894912233943438	[546]	[73,59,NaN]	-8	hSpCas9	negative selection	10058932
23556277	23556300	18	+	27869803	HPAFII	viability after 31 days	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-1.046227704265521	[107]	[25,32,NaN]	-6	hSpCas9	negative selection	10058933
23560324	23560347	18	+	27869803	HPAFII	viability after 31 days	AGGATCGTCCAGGGAGCAGGAGG	NPC1	ENSG00000141458	-2.068105899746896	[113]	[20,8,NaN]	-8	hSpCas9	negative selection	10058934
23561454	23561477	18	+	27869803	HPAFII	viability after 31 days	CTTCCCACACAGGAGTCCCAGGG	NPC1	ENSG00000141458	-0.6925253601813812	[200]	[109,25,NaN]	-4	hSpCas9	negative selection	10058935
23586289	23586312	18	+	27869803	HPAFII	viability after 31 days	GCGCTGGACACAGTAGCAGCAGG	NPC1	ENSG00000141458	0.8333711996752582	[0]	[0,0,NaN]	6	hSpCas9	negative selection	10058936
23539874	23539897	18	-	28162770	P31FUJ	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	-0.28303650693451504	[262]	[253]	-3	hSpCas9	negative selection	10201711
23538563	23538586	18	+	28162770	P31FUJ	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	0.38386915603411564	[104]	[160]	4	hSpCas9	negative selection	10201712
23586301	23586324	18	+	28162770	P31FUJ	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-0.7698302280718328	[73]	[50]	-5	hSpCas9	negative selection	10201713
23560460	23560483	18	-	28162770	P31FUJ	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	1.1297678749703297	[209]	[539]	9	hSpCas9	negative selection	10201714
23556277	23556300	18	+	28162770	P31FUJ	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.5018532290646267	[124]	[207]	5	hSpCas9	negative selection	10201715
23556250	23556273	18	+	28162770	P31FUJ	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	-0.39974458118283335	[301]	[268]	-4	hSpCas9	negative selection	10201716
23548068	23548091	18	+	28162770	P31FUJ	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	0.4987089596597194	[105]	[175]	5	hSpCas9	negative selection	10201717
23548026	23548049	18	-	28162770	P31FUJ	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	-0.24366319704614547	[399]	[396]	-2	hSpCas9	negative selection	10201718
23544440	23544463	18	+	28162770	P31FUJ	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.25380522432820296	[348]	[488]	2	hSpCas9	negative selection	10201719
23538607	23538630	18	-	28162770	P31FUJ	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	0.3669270070156897	[323]	[490]	4	hSpCas9	negative selection	10201720
23539874	23539897	18	-	28162770	TF1	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	NaN	[NaN]	[363]	1	hSpCas9	negative selection	10371077
23538563	23538586	18	+	28162770	TF1	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	NaN	[NaN]	[80]	1	hSpCas9	negative selection	10371078
23586301	23586324	18	+	28162770	TF1	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10371079
23560460	23560483	18	-	28162770	TF1	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	NaN	[NaN]	[367]	1	hSpCas9	negative selection	10371080
23556277	23556300	18	+	28162770	TF1	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	NaN	[NaN]	[245]	1	hSpCas9	negative selection	10371081
23556250	23556273	18	+	28162770	TF1	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	NaN	[NaN]	[268]	1	hSpCas9	negative selection	10371082
23548068	23548091	18	+	28162770	TF1	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	NaN	[NaN]	[115]	1	hSpCas9	negative selection	10371083
23548026	23548049	18	-	28162770	TF1	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	NaN	[NaN]	[327]	1	hSpCas9	negative selection	10371084
23544440	23544463	18	+	28162770	TF1	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	NaN	[NaN]	[474]	1	hSpCas9	negative selection	10371085
23538607	23538630	18	-	28162770	TF1	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	NaN	[NaN]	[456]	1	hSpCas9	negative selection	10371086
23539874	23539897	18	-	28162770	SKM1	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	-0.23046654337736308	[72]	[109]	-2	hSpCas9	negative selection	10540443
23538563	23538586	18	+	28162770	SKM1	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	-1.7835275502073697	[36]	[18]	-8	hSpCas9	negative selection	10540444
23586301	23586324	18	+	28162770	SKM1	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	0.4999263968653569	[21]	[54]	5	hSpCas9	negative selection	10540445
23560460	23560483	18	-	28162770	SKM1	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	-0.056466951659028486	[79]	[135]	0	hSpCas9	negative selection	10540446
23556277	23556300	18	+	28162770	SKM1	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.3019870192534479	[38]	[84]	3	hSpCas9	negative selection	10540447
23556250	23556273	18	+	28162770	SKM1	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	-0.17158613581223325	[78]	[123]	-1	hSpCas9	negative selection	10540448
23548068	23548091	18	+	28162770	SKM1	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	-0.615550820554579	[25]	[29]	-5	hSpCas9	negative selection	10540449
23548026	23548049	18	-	28162770	SKM1	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	-1.007216570488913	[82]	[72]	-6	hSpCas9	negative selection	10540450
23544440	23544463	18	+	28162770	SKM1	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	-0.3289616867418884	[80]	[113]	-3	hSpCas9	negative selection	10540451
23538607	23538630	18	-	28162770	SKM1	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	-0.8709112985029519	[59]	[57]	-6	hSpCas9	negative selection	10540452
23539874	23539897	18	-	28162770	SKM1	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	-0.23046654337736308	[72]	[109]	-2	hSpCas9	negative selection	10709809
23538563	23538586	18	+	28162770	SKM1	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	-1.7835275502073697	[36]	[18]	-8	hSpCas9	negative selection	10709810
23586301	23586324	18	+	28162770	SKM1	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	0.4999263968653569	[21]	[54]	5	hSpCas9	negative selection	10709811
23560460	23560483	18	-	28162770	SKM1	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	-0.056466951659028486	[79]	[135]	0	hSpCas9	negative selection	10709812
23556277	23556300	18	+	28162770	SKM1	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.3019870192534479	[38]	[84]	3	hSpCas9	negative selection	10709813
23556250	23556273	18	+	28162770	SKM1	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	-0.17158613581223325	[78]	[123]	-1	hSpCas9	negative selection	10709814
23548068	23548091	18	+	28162770	SKM1	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	-0.615550820554579	[25]	[29]	-5	hSpCas9	negative selection	10709815
23548026	23548049	18	-	28162770	SKM1	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	-1.007216570488913	[82]	[72]	-6	hSpCas9	negative selection	10709816
23544440	23544463	18	+	28162770	SKM1	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	-0.3289616867418884	[80]	[113]	-3	hSpCas9	negative selection	10709817
23538607	23538630	18	-	28162770	SKM1	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	-0.8709112985029519	[59]	[57]	-6	hSpCas9	negative selection	10709818
23539874	23539897	18	-	28162770	PL21	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	0.21086602108237867	[267]	[134]	1	hSpCas9	negative selection	10879175
23538563	23538586	18	+	28162770	PL21	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	1.9961257224677267	[90]	[157]	9	hSpCas9	negative selection	10879176
23586301	23586324	18	+	28162770	PL21	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-2.6906313157559216	[88]	[5]	-9	hSpCas9	negative selection	10879177
23560460	23560483	18	-	28162770	PL21	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	0.8690805078498292	[316]	[251]	7	hSpCas9	negative selection	10879178
23556277	23556300	18	+	28162770	PL21	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	1.6624828285465205	[134]	[185]	9	hSpCas9	negative selection	10879179
23556250	23556273	18	+	28162770	PL21	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	0.6023758315450743	[282]	[186]	5	hSpCas9	negative selection	10879180
23548068	23548091	18	+	28162770	PL21	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	0.9040075204792953	[96]	[78]	7	hSpCas9	negative selection	10879181
23548026	23548049	18	-	28162770	PL21	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	0.978624478093793	[273]	[234]	7	hSpCas9	negative selection	10879182
23544440	23544463	18	+	28162770	PL21	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.0907283977687382	[355]	[164]	0	hSpCas9	negative selection	10879183
23538607	23538630	18	-	28162770	PL21	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	0.013141099688066205	[254]	[111]	0	hSpCas9	negative selection	10879184
23539874	23539897	18	-	28162770	P31FUJ	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	-0.28303650693451504	[262]	[253]	-3	hSpCas9	negative selection	11048541
23538563	23538586	18	+	28162770	P31FUJ	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	0.38386915603411564	[104]	[160]	4	hSpCas9	negative selection	11048542
23586301	23586324	18	+	28162770	P31FUJ	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-0.7698302280718328	[73]	[50]	-5	hSpCas9	negative selection	11048543
23560460	23560483	18	-	28162770	P31FUJ	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	1.1297678749703297	[209]	[539]	9	hSpCas9	negative selection	11048544
23556277	23556300	18	+	28162770	P31FUJ	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.5018532290646267	[124]	[207]	5	hSpCas9	negative selection	11048545
23556250	23556273	18	+	28162770	P31FUJ	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	-0.39974458118283335	[301]	[268]	-4	hSpCas9	negative selection	11048546
23548068	23548091	18	+	28162770	P31FUJ	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	0.4987089596597194	[105]	[175]	5	hSpCas9	negative selection	11048547
23548026	23548049	18	-	28162770	P31FUJ	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	-0.24366319704614547	[399]	[396]	-2	hSpCas9	negative selection	11048548
23544440	23544463	18	+	28162770	P31FUJ	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.25380522432820296	[348]	[488]	2	hSpCas9	negative selection	11048549
23538607	23538630	18	-	28162770	P31FUJ	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	0.3669270070156897	[323]	[490]	4	hSpCas9	negative selection	11048550
23539874	23539897	18	-	28162770	OCIAML5	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	0.6960591616767878	[118]	[347]	6	hSpCas9	negative selection	11217907
23538563	23538586	18	+	28162770	OCIAML5	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	0.9173205009945866	[65]	[224]	7	hSpCas9	negative selection	11217908
23586301	23586324	18	+	28162770	OCIAML5	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-4.125085065270413	[28]	[2]	-9	hSpCas9	negative selection	11217909
23560460	23560483	18	-	28162770	OCIAML5	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	0.06363519482934299	[184]	[348]	0	hSpCas9	negative selection	11217910
23556277	23556300	18	+	28162770	OCIAML5	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	1.44398289219776	[44]	[220]	9	hSpCas9	negative selection	11217911
23556250	23556273	18	+	28162770	OCIAML5	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	-0.04702923169979223	[177]	[310]	0	hSpCas9	negative selection	11217912
23548068	23548091	18	+	28162770	OCIAML5	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	-0.44996812729265134	[83]	[110]	-3	hSpCas9	negative selection	11217913
23548026	23548049	18	-	28162770	OCIAML5	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	0.5534481542963403	[170]	[452]	5	hSpCas9	negative selection	11217914
23544440	23544463	18	+	28162770	OCIAML5	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.5072614958285591	[197]	[507]	4	hSpCas9	negative selection	11217915
23538607	23538630	18	-	28162770	OCIAML5	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	1.2290701918614086	[120]	[511]	9	hSpCas9	negative selection	11217916
23539874	23539897	18	-	28162770	EOL1	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	1.7090325443078798	[435]	[750]	9	hSpCas9	negative selection	11387273
23538563	23538586	18	+	28162770	EOL1	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	1.448706993229491	[104]	[150]	9	hSpCas9	negative selection	11387274
23586301	23586324	18	+	28162770	EOL1	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	0.025993035130080444	[150]	[80]	0	hSpCas9	negative selection	11387275
23560460	23560483	18	-	28162770	EOL1	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	0.4299134457941073	[502]	[356]	4	hSpCas9	negative selection	11387276
23556277	23556300	18	+	28162770	EOL1	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.11852313549090063	[270]	[154]	1	hSpCas9	negative selection	11387277
23556250	23556273	18	+	28162770	EOL1	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	0.0771699146028082	[465]	[258]	0	hSpCas9	negative selection	11387278
23548068	23548091	18	+	28162770	EOL1	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	-0.8875922130524464	[150]	[42]	-6	hSpCas9	negative selection	11387279
23548026	23548049	18	-	28162770	EOL1	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	0.35349087287459663	[412]	[277]	3	hSpCas9	negative selection	11387280
23544440	23544463	18	+	28162770	EOL1	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.1824843097646494	[377]	[225]	1	hSpCas9	negative selection	11387281
23538607	23538630	18	-	28162770	EOL1	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	0.7421710290819657	[319]	[281]	6	hSpCas9	negative selection	11387282
23539874	23539897	18	-	28162770	MOLM13	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	0.7475066715739767	[345]	[419]	5	hSpCas9	negative selection	11556639
23538563	23538586	18	+	28162770	MOLM13	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	0.4678893815445787	[141]	[141]	3	hSpCas9	negative selection	11556640
23586301	23586324	18	+	28162770	MOLM13	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-5.300294943232348	[108]	[1]	-9	hSpCas9	negative selection	11556641
23560460	23560483	18	-	28162770	MOLM13	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	0.06674227004917505	[378]	[286]	0	hSpCas9	negative selection	11556642
23556277	23556300	18	+	28162770	MOLM13	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.596337747010732	[246]	[269]	4	hSpCas9	negative selection	11556643
23556250	23556273	18	+	28162770	MOLM13	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	0.9354290205308298	[370]	[512]	7	hSpCas9	negative selection	11556644
23548068	23548091	18	+	28162770	MOLM13	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	1.4917361234989466	[149]	[304]	9	hSpCas9	negative selection	11556645
23548026	23548049	18	-	28162770	MOLM13	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	0.6864243272115129	[427]	[497]	5	hSpCas9	negative selection	11556646
23544440	23544463	18	+	28162770	MOLM13	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.15098185612177406	[501]	[402]	1	hSpCas9	negative selection	11556647
23538607	23538630	18	-	28162770	MOLM13	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	0.9425698272508245	[307]	[427]	7	hSpCas9	negative selection	11556648
23539874	23539897	18	-	28162770	HEL	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	0.2873725453944882	[370]	[289]	2	hSpCas9	negative selection	11726005
23538563	23538586	18	+	28162770	HEL	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	0.6841587593803377	[102]	[105]	6	hSpCas9	negative selection	11726006
23586301	23586324	18	+	28162770	HEL	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	1.2424983346495937	[96]	[146]	9	hSpCas9	negative selection	11726007
23560460	23560483	18	-	28162770	HEL	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	0.9888160762552908	[390]	[496]	8	hSpCas9	negative selection	11726008
23556277	23556300	18	+	28162770	HEL	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	1.7530622469063553	[150]	[325]	9	hSpCas9	negative selection	11726009
23556250	23556273	18	+	28162770	HEL	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	0.1411513007650793	[394]	[278]	1	hSpCas9	negative selection	11726010
23548068	23548091	18	+	28162770	HEL	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	-0.3572611679996429	[93]	[46]	-2	hSpCas9	negative selection	11726011
23548026	23548049	18	-	28162770	HEL	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	0.5829294367650532	[393]	[377]	5	hSpCas9	negative selection	11726012
23544440	23544463	18	+	28162770	HEL	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.4495064570659758	[350]	[306]	4	hSpCas9	negative selection	11726013
23538607	23538630	18	-	28162770	HEL	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	-0.35726116799964314	[253]	[126]	-3	hSpCas9	negative selection	11726014
23539874	23539897	18	-	28162770	MV411	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	1.235106748872056	[234]	[465]	9	hSpCas9	negative selection	11895371
23538563	23538586	18	+	28162770	MV411	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	1.3289674362793735	[85]	[181]	9	hSpCas9	negative selection	11895372
23586301	23586324	18	+	28162770	MV411	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-1.5688504960448368	[80]	[22]	-7	hSpCas9	negative selection	11895373
23560460	23560483	18	-	28162770	MV411	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	1.0747981646434268	[265]	[471]	8	hSpCas9	negative selection	11895374
23556277	23556300	18	+	28162770	MV411	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.9043339457455757	[162]	[256]	7	hSpCas9	negative selection	11895375
23556250	23556273	18	+	28162770	MV411	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	0.5262969237782518	[271]	[329]	5	hSpCas9	negative selection	11895376
23548068	23548091	18	+	28162770	MV411	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	0.6501967202831823	[117]	[155]	6	hSpCas9	negative selection	11895377
23548026	23548049	18	-	28162770	MV411	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	1.4039868302232568	[300]	[670]	9	hSpCas9	negative selection	11895378
23544440	23544463	18	+	28162770	MV411	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.8806552201111527	[293]	[455]	7	hSpCas9	negative selection	11895379
23538607	23538630	18	-	28162770	MV411	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	-0.17260062955443495	[288]	[215]	-1	hSpCas9	negative selection	11895380
23539874	23539897	18	-	28162770	MONOMAC1	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	-0.4788078154749335	[185]	[152]	-4	hSpCas9	negative selection	12064737
23538563	23538586	18	+	28162770	MONOMAC1	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	0.17883005493861232	[83]	[108]	1	hSpCas9	negative selection	12064738
23586301	23586324	18	+	28162770	MONOMAC1	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-0.27103742850333057	[59]	[56]	-2	hSpCas9	negative selection	12064739
23560460	23560483	18	-	28162770	MONOMAC1	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	0.7654884475217832	[194]	[379]	7	hSpCas9	negative selection	12064740
23556277	23556300	18	+	28162770	MONOMAC1	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.6142015094852784	[105]	[185]	6	hSpCas9	negative selection	12064741
23556250	23556273	18	+	28162770	MONOMAC1	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	0.7186649186337862	[184]	[348]	7	hSpCas9	negative selection	12064742
23548068	23548091	18	+	28162770	MONOMAC1	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	-0.5380737648946207	[75]	[59]	-4	hSpCas9	negative selection	12064743
23548026	23548049	18	-	28162770	MONOMAC1	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	0.11671731638210847	[176]	[219]	1	hSpCas9	negative selection	12064744
23544440	23544463	18	+	28162770	MONOMAC1	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.9066544559826717	[207]	[446]	8	hSpCas9	negative selection	12064745
23538607	23538630	18	-	28162770	MONOMAC1	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	1.0070547575339506	[101]	[234]	8	hSpCas9	negative selection	12064746
23539874	23539897	18	-	28162770	OCIAML2	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	0.10897944098478807	[44]	[268]	1	hSpCas9	negative selection	12234103
23538563	23538586	18	+	28162770	OCIAML2	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	-0.8076648125197317	[17]	[56]	-5	hSpCas9	negative selection	12234104
23586301	23586324	18	+	28162770	OCIAML2	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	-1.1976113308357452	[11]	[28]	-7	hSpCas9	negative selection	12234105
23560460	23560483	18	-	28162770	OCIAML2	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	0.19627428901517097	[76]	[488]	1	hSpCas9	negative selection	12234106
23556277	23556300	18	+	28162770	OCIAML2	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	0.034898207984589924	[27]	[158]	0	hSpCas9	negative selection	12234107
23556250	23556273	18	+	28162770	OCIAML2	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	0.20659118333098359	[52]	[338]	2	hSpCas9	negative selection	12234108
23548068	23548091	18	+	28162770	OCIAML2	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	0.28425767692130754	[15]	[107]	2	hSpCas9	negative selection	12234109
23548026	23548049	18	-	28162770	OCIAML2	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	0.22004211665010998	[56]	[367]	2	hSpCas9	negative selection	12234110
23544440	23544463	18	+	28162770	OCIAML2	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.5596729349213647	[52]	[432]	5	hSpCas9	negative selection	12234111
23538607	23538630	18	-	28162770	OCIAML2	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	0.19612676664264234	[39]	[253]	1	hSpCas9	negative selection	12234112
23539874	23539897	18	-	28162770	OCIAML3	viability	GGGCAGAACATGGTGTGCGGCGG	NPC1	ENSG00000141458	1.0673579320560744	[94]	[600]	8	hSpCas9	negative selection	12403469
23538563	23538586	18	+	28162770	OCIAML3	viability	GGGTTATCCGAAAGGAACATGGG	NPC1	ENSG00000141458	1.4701226970955523	[21]	[183]	9	hSpCas9	negative selection	12403470
23586301	23586324	18	+	28162770	OCIAML3	viability	GTAGCAGCAGGAGGAGGCCAAGG	NPC1	ENSG00000141458	0.06895737239826594	[23]	[75]	0	hSpCas9	negative selection	12403471
23560460	23560483	18	-	28162770	OCIAML3	viability	AGATTTTCCAGTCCATGGGATGG	NPC1	ENSG00000141458	0.9934573676001631	[95]	[576]	8	hSpCas9	negative selection	12403472
23556277	23556300	18	+	28162770	OCIAML3	viability	AAGGGTACATCAGCTCCCGAAGG	NPC1	ENSG00000141458	-0.8419351537677484	[37]	[63]	-6	hSpCas9	negative selection	12403473
23556250	23556273	18	+	28162770	OCIAML3	viability	AGTATCTGTATGTCAAGCGGAGG	NPC1	ENSG00000141458	-0.43050890804128356	[74]	[167]	-3	hSpCas9	negative selection	12403474
23548068	23548091	18	+	28162770	OCIAML3	viability	GAAGGTAATCACAAGGGCAGTGG	NPC1	ENSG00000141458	-0.1554346265845301	[37]	[102]	-1	hSpCas9	negative selection	12403475
23548026	23548049	18	-	28162770	OCIAML3	viability	ATGATACAGAGAAGCTCCAGAGG	NPC1	ENSG00000141458	0.08406426478847451	[89]	[287]	0	hSpCas9	negative selection	12403476
23544440	23544463	18	+	28162770	OCIAML3	viability	AATGTAGCTGAAGACACCCAAGG	NPC1	ENSG00000141458	0.6861002788685722	[76]	[373]	6	hSpCas9	negative selection	12403477
23538607	23538630	18	-	28162770	OCIAML3	viability	AAGGCAAACAGAGGCCTCAGGGG	NPC1	ENSG00000141458	-0.19065194609295477	[61]	[163]	-1	hSpCas9	negative selection	12403478