Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 8131
• Symbol: NPRL3
• Description: NPR3 like, GATOR1 complex subunit

DataSource: http://genomecrispr.dkfz.de/#!/results/NPRL3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
98210	98233	16	+	26627737	DLD1	viability	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	-1.0100304077523863	[1106]	[226,137,151]	-7	hSpCas9	negative selection	792701
100487	100510	16	+	26627737	DLD1	viability	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-0.4618436321738079	[354]	[157,91,3]	-5	hSpCas9	negative selection	792706
110553	110576	16	-	26627737	DLD1	viability	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	0.9371277888349528	[419]	[84,303,351]	8	hSpCas9	negative selection	792776
112695	112718	16	+	26627737	DLD1	viability	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.14134475896638887	[767]	[411,357,59]	1	hSpCas9	negative selection	792782
130555	130578	16	-	26627737	DLD1	viability	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.07941991249191904	[1061]	[400,222,412]	0	hSpCas9	negative selection	792809
138144	138167	16	+	26627737	DLD1	viability	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	0.7110525775442199	[148]	[112,89,32]	7	hSpCas9	negative selection	792859
98210	98233	16	+	26627737	GBM cells	viability after 5 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	0.07599866790086421	[267]	[119,182]	1	hSpCas9	negative selection	875016
100487	100510	16	+	26627737	GBM cells	viability after 5 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-0.5891870865828814	[107]	[51,24]	-7	hSpCas9	negative selection	875021
110553	110576	16	-	26627737	GBM cells	viability after 5 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	0.3408025938139606	[172]	[133,100]	5	hSpCas9	negative selection	875091
112695	112718	16	+	26627737	GBM cells	viability after 5 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.525696551301469	[271]	[204,214]	7	hSpCas9	negative selection	875097
130555	130578	16	-	26627737	GBM cells	viability after 5 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	-0.19537372070307713	[489]	[286,171]	-3	hSpCas9	negative selection	875124
138144	138167	16	+	26627737	GBM cells	viability after 5 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	0.15363301250747563	[144]	[101,70]	2	hSpCas9	negative selection	875174
98210	98233	16	+	26627737	GBM cells	viability after 13 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	0.33049594012513994	[267]	[221,150]	4	hSpCas9	negative selection	957331
100487	100510	16	+	26627737	GBM cells	viability after 13 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-0.07169421225614658	[107]	[52,57]	-1	hSpCas9	negative selection	957336
110553	110576	16	-	26627737	GBM cells	viability after 13 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	1.042677518937194	[172]	[242,152]	9	hSpCas9	negative selection	957406
112695	112718	16	+	26627737	GBM cells	viability after 13 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.49722042234322983	[271]	[204,210]	6	hSpCas9	negative selection	957412
130555	130578	16	-	26627737	GBM cells	viability after 13 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	-0.55427873051585	[489]	[217,150]	-6	hSpCas9	negative selection	957439
138144	138167	16	+	26627737	GBM cells	viability after 13 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	0.39075290756598585	[144]	[122,86]	5	hSpCas9	negative selection	957489
98210	98233	16	+	26627737	GBM cells	viability after 21 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	0.9650196565972107	[267]	[278,288]	8	hSpCas9	negative selection	1039646
100487	100510	16	+	26627737	GBM cells	viability after 21 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	0.729054556253542	[107]	[102,91]	7	hSpCas9	negative selection	1039651
110553	110576	16	-	26627737	GBM cells	viability after 21 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	0.8538640386267154	[172]	[172,166]	8	hSpCas9	negative selection	1039721
112695	112718	16	+	26627737	GBM cells	viability after 21 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.7640585324073503	[271]	[251,249]	7	hSpCas9	negative selection	1039727
130555	130578	16	-	26627737	GBM cells	viability after 21 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	-0.8649341076633354	[489]	[153,138]	-6	hSpCas9	negative selection	1039754
138144	138167	16	+	26627737	GBM cells	viability after 21 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	-0.07599582320236808	[144]	[80,68]	0	hSpCas9	negative selection	1039804
98210	98233	16	+	26627737	RPE1	viability after 9 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	-0.4320306136865979	[2450]	[449,721]	-3	hSpCas9	negative selection	1121961
100487	100510	16	+	26627737	RPE1	viability after 9 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-1.4240152968090634	[1021]	[144,85]	-8	hSpCas9	negative selection	1121966
110553	110576	16	-	26627737	RPE1	viability after 9 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	-0.02116804200998096	[938]	[290,287]	0	hSpCas9	negative selection	1122036
112695	112718	16	+	26627737	RPE1	viability after 9 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.18252046296765667	[1736]	[593,646]	1	hSpCas9	negative selection	1122042
130555	130578	16	-	26627737	RPE1	viability after 9 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.24777063606117222	[1328]	[414,595]	1	hSpCas9	negative selection	1122069
138144	138167	16	+	26627737	RPE1	viability after 9 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	-1.6609501781638423	[788]	[71,85]	-8	hSpCas9	negative selection	1122119
98210	98233	16	+	26627737	RPE1	viability after 12 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	-0.5802791051441307	[2450]	[403,478]	-4	hSpCas9	negative selection	1204276
100487	100510	16	+	26627737	RPE1	viability after 12 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-1.5932734290657868	[1021]	[124,54]	-8	hSpCas9	negative selection	1204281
110553	110576	16	-	26627737	RPE1	viability after 12 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	-0.4381606733092053	[938]	[107,268]	-3	hSpCas9	negative selection	1204351
112695	112718	16	+	26627737	RPE1	viability after 12 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.6473441878769066	[1736]	[711,750]	4	hSpCas9	negative selection	1204357
130555	130578	16	-	26627737	RPE1	viability after 12 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.7970408985456918	[1328]	[497,749]	5	hSpCas9	negative selection	1204384
138144	138167	16	+	26627737	RPE1	viability after 12 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	-1.2767945277854993	[788]	[69,105]	-7	hSpCas9	negative selection	1204434
98210	98233	16	+	26627737	RPE1	viability after 15 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	-0.6700378050578333	[2450]	[533,340]	-4	hSpCas9	negative selection	1286591
100487	100510	16	+	26627737	RPE1	viability after 15 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-1.0547294487554846	[1021]	[213,66]	-6	hSpCas9	negative selection	1286596
110553	110576	16	-	26627737	RPE1	viability after 15 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	-0.19716613725104404	[938]	[248,214]	-1	hSpCas9	negative selection	1286666
112695	112718	16	+	26627737	RPE1	viability after 15 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.6846335222435842	[1736]	[943,640]	4	hSpCas9	negative selection	1286672
130555	130578	16	-	26627737	RPE1	viability after 15 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.4526444074214553	[1328]	[373,649]	3	hSpCas9	negative selection	1286699
138144	138167	16	+	26627737	RPE1	viability after 15 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	-0.9736012005817184	[788]	[132,94]	-6	hSpCas9	negative selection	1286749
98210	98233	16	+	26627737	RPE1	viability after 18 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	-0.7486673391666313	[2450]	[310,481]	-5	hSpCas9	negative selection	1368906
100487	100510	16	+	26627737	RPE1	viability after 18 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-1.4022146020153428	[1021]	[99,108]	-7	hSpCas9	negative selection	1368911
110553	110576	16	-	26627737	RPE1	viability after 18 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	-0.13294259661589056	[938]	[131,336]	-1	hSpCas9	negative selection	1368981
112695	112718	16	+	26627737	RPE1	viability after 18 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.3749888022587766	[1736]	[677,532]	2	hSpCas9	negative selection	1368987
130555	130578	16	-	26627737	RPE1	viability after 18 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.8841579768461363	[1328]	[456,880]	5	hSpCas9	negative selection	1369014
138144	138167	16	+	26627737	RPE1	viability after 18 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	-1.2082749998313196	[788]	[81,102]	-6	hSpCas9	negative selection	1369064
98210	98233	16	+	26627737	HeLa	viability after 8 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	-0.7343063101155821	[798]	[330,160,164]	-6	hSpCas9	negative selection	1451221
100487	100510	16	+	26627737	HeLa	viability after 8 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-1.3015754060349987	[350]	[70,41,73]	-8	hSpCas9	negative selection	1451226
110553	110576	16	-	26627737	HeLa	viability after 8 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	1.8599356057639418	[195]	[194,405,302]	9	hSpCas9	negative selection	1451296
112695	112718	16	+	26627737	HeLa	viability after 8 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.07121561930058318	[712]	[176,292,464]	0	hSpCas9	negative selection	1451302
130555	130578	16	-	26627737	HeLa	viability after 8 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	-0.5954955084237051	[847]	[322,212,215]	-5	hSpCas9	negative selection	1451329
138144	138167	16	+	26627737	HeLa	viability after 8 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	0.5324615028249049	[169]	[253,16,83]	5	hSpCas9	negative selection	1451379
98210	98233	16	+	26627737	HeLa	viability after 12 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	-0.3048645640822478	[798]	[180,204,419]	-3	hSpCas9	negative selection	1533536
100487	100510	16	+	26627737	HeLa	viability after 12 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-1.2144992322372998	[350]	[84,16,90]	-8	hSpCas9	negative selection	1533541
110553	110576	16	-	26627737	HeLa	viability after 12 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	1.2145656180191686	[195]	[265,170,130]	8	hSpCas9	negative selection	1533611
112695	112718	16	+	26627737	HeLa	viability after 12 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.7460567380109953	[712]	[591,337,571]	6	hSpCas9	negative selection	1533617
130555	130578	16	-	26627737	HeLa	viability after 12 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	-0.27660480016310374	[847]	[407,188,284]	-2	hSpCas9	negative selection	1533644
138144	138167	16	+	26627737	HeLa	viability after 12 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	1.3015396916937132	[169]	[163,184,168]	8	hSpCas9	negative selection	1533694
98210	98233	16	+	26627737	HeLa	viability after 15 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	-0.8375697647731061	[798]	[195,105,248]	-6	hSpCas9	negative selection	1615851
100487	100510	16	+	26627737	HeLa	viability after 15 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-1.8482683902042187	[350]	[69,16,30]	-9	hSpCas9	negative selection	1615856
110553	110576	16	-	26627737	HeLa	viability after 15 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	0.607483010518071	[195]	[23,50,304]	5	hSpCas9	negative selection	1615926
112695	112718	16	+	26627737	HeLa	viability after 15 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	1.2026352998484253	[712]	[652,639,714]	8	hSpCas9	negative selection	1615932
130555	130578	16	-	26627737	HeLa	viability after 15 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	-0.032556502532549825	[847]	[681,146,165]	0	hSpCas9	negative selection	1615959
138144	138167	16	+	26627737	HeLa	viability after 15 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	0.32329411046310974	[169]	[81,52,127]	2	hSpCas9	negative selection	1616009
98210	98233	16	+	26627737	HeLa	viability after 18 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	-0.8836342584564497	[798]	[116,91,248]	-7	hSpCas9	negative selection	1698166
100487	100510	16	+	26627737	HeLa	viability after 18 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-1.8009989978244283	[350]	[47,15,30]	-9	hSpCas9	negative selection	1698171
110553	110576	16	-	26627737	HeLa	viability after 18 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	0.5798475907737528	[195]	[10,42,304]	5	hSpCas9	negative selection	1698241
112695	112718	16	+	26627737	HeLa	viability after 18 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	1.229809471668449	[712]	[449,545,714]	8	hSpCas9	negative selection	1698247
130555	130578	16	-	26627737	HeLa	viability after 18 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	-0.032503316605050125	[847]	[458,119,165]	0	hSpCas9	negative selection	1698274
138144	138167	16	+	26627737	HeLa	viability after 18 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	0.33754788526585544	[169]	[54,45,127]	3	hSpCas9	negative selection	1698324
98210	98233	16	+	26627737	HCT116	viability after 6 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	-0.33109965176799516	[873]	[105,110]	-2	hSpCas9	negative selection	1780481
100487	100510	16	+	26627737	HCT116	viability after 6 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-2.7632337603913824	[472]	[28,0]	-9	hSpCas9	negative selection	1780486
110553	110576	16	-	26627737	HCT116	viability after 6 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	-0.3499986744461989	[197]	[26,22]	-2	hSpCas9	negative selection	1780556
112695	112718	16	+	26627737	HCT116	viability after 6 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.027525504829333025	[1528]	[244,244]	0	hSpCas9	negative selection	1780562
130555	130578	16	-	26627737	HCT116	viability after 6 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.26734606661928806	[1144]	[322,157]	1	hSpCas9	negative selection	1780589
138144	138167	16	+	26627737	HCT116	viability after 6 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	0.09137579816022812	[370]	[172,0]	0	hSpCas9	negative selection	1780639
98210	98233	16	+	26627737	HCT116	viability after 8 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	0.1025723655388453	[468]	[359,204,268]	1	hSpCas9	negative selection	1862796
100487	100510	16	+	26627737	HCT116	viability after 8 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	0.860762721018822	[116]	[159,74,116]	7	hSpCas9	negative selection	1862801
110553	110576	16	-	26627737	HCT116	viability after 8 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	0.9201550155367433	[145]	[157,161,136]	8	hSpCas9	negative selection	1862871
112695	112718	16	+	26627737	HCT116	viability after 8 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.4556626037145328	[692]	[504,398,664]	5	hSpCas9	negative selection	1862877
130555	130578	16	-	26627737	HCT116	viability after 8 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.3949171140357952	[593]	[417,451,420]	4	hSpCas9	negative selection	1862904
138144	138167	16	+	26627737	HCT116	viability after 8 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	-0.43140576702404143	[244]	[145,42,111]	-5	hSpCas9	negative selection	1862954
98210	98233	16	+	26627737	HCT116	viability after 9 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	0.9695506969109401	[873]	[394,505]	6	hSpCas9	negative selection	1945111
100487	100510	16	+	26627737	HCT116	viability after 9 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	0.11476174196679612	[472]	[305,2]	0	hSpCas9	negative selection	1945116
110553	110576	16	-	26627737	HCT116	viability after 9 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	2.351774699250168	[197]	[65,430]	9	hSpCas9	negative selection	1945186
112695	112718	16	+	26627737	HCT116	viability after 9 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.3084543492451042	[1528]	[890,200]	2	hSpCas9	negative selection	1945192
130555	130578	16	-	26627737	HCT116	viability after 9 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	-0.09740730591733715	[1144]	[182,366]	0	hSpCas9	negative selection	1945219
138144	138167	16	+	26627737	HCT116	viability after 9 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	0.4385169159650002	[370]	[169,105]	3	hSpCas9	negative selection	1945269
98210	98233	16	+	26627737	HCT116	viability after 12 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	0.2294379292089792	[468]	[456,242,150]	2	hSpCas9	negative selection	2027426
100487	100510	16	+	26627737	HCT116	viability after 12 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	0.4149694713995007	[116]	[81,125,38]	4	hSpCas9	negative selection	2027431
110553	110576	16	-	26627737	HCT116	viability after 12 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	1.513199623233245	[145]	[288,264,97]	9	hSpCas9	negative selection	2027501
112695	112718	16	+	26627737	HCT116	viability after 12 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.5701019312524347	[692]	[466,394,762]	5	hSpCas9	negative selection	2027507
130555	130578	16	-	26627737	HCT116	viability after 12 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.29824802524632643	[593]	[293,447,418]	3	hSpCas9	negative selection	2027534
138144	138167	16	+	26627737	HCT116	viability after 12 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	-0.6097883190628162	[244]	[111,55,81]	-6	hSpCas9	negative selection	2027584
98210	98233	16	+	26627737	HCT116	viability after 15 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	0.23016055152253934	[468]	[398,333,225]	2	hSpCas9	negative selection	2109741
100487	100510	16	+	26627737	HCT116	viability after 15 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	0.8469506452915884	[116]	[145,128,90]	7	hSpCas9	negative selection	2109746
110553	110576	16	-	26627737	HCT116	viability after 15 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	1.6934918654376716	[145]	[407,297,125]	9	hSpCas9	negative selection	2109816
112695	112718	16	+	26627737	HCT116	viability after 15 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.8924711581540732	[692]	[705,732,772]	7	hSpCas9	negative selection	2109822
130555	130578	16	-	26627737	HCT116	viability after 15 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.2941734695754492	[593]	[439,439,377]	3	hSpCas9	negative selection	2109849
138144	138167	16	+	26627737	HCT116	viability after 15 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	-0.03195737816748567	[244]	[131,127,151]	0	hSpCas9	negative selection	2109899
98210	98233	16	+	26627737	HCT116	viability after 18 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	1.1112518311541895	[468]	[660,380,431]	8	hSpCas9	negative selection	2192056
100487	100510	16	+	26627737	HCT116	viability after 18 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	0.8852295326571153	[116]	[115,111,83]	7	hSpCas9	negative selection	2192061
110553	110576	16	-	26627737	HCT116	viability after 18 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	1.4365948581266559	[145]	[185,245,134]	8	hSpCas9	negative selection	2192131
112695	112718	16	+	26627737	HCT116	viability after 18 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.7789375701976036	[692]	[464,590,671]	6	hSpCas9	negative selection	2192137
130555	130578	16	-	26627737	HCT116	viability after 18 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	1.160178475555299	[593]	[832,591,496]	8	hSpCas9	negative selection	2192164
138144	138167	16	+	26627737	HCT116	viability after 18 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	-0.8012539706334074	[244]	[32,72,98]	-6	hSpCas9	negative selection	2192214
138779	138802	16	-	25494202	A375	resistance to PLX-4720 (puromycin)	GACAGCACCGCGGAACTCGGTGG	NPRL3	ENSG00000103148	-0.7230851890410792	[65,9]	[6,1]	-4	dCas9-VP64	positive selection	2392845
138803	138826	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGCCGTACGGTTCGCGTTTGG	NPRL3	ENSG00000103148	1.516729061374955	[79,257]	[22,197]	5	dCas9-VP64	positive selection	2392846
124982	125005	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATCGCTTGAACCCTAG	NPRL3	ENSG00000103148	-1.1949452889942442	[147,110]	[6,17]	-7	dCas9-VP64	positive selection	2450048
131132	131155	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGAAACCAGCCTGGCCAACATGG	NPRL3	ENSG00000103148	0.4780801974693999	[28,77]	[7,24]	2	dCas9-VP64	positive selection	2472910
138779	138802	16	-	25494202	A375	resistance to PLX-4720 (zeocin)	GACAGCACCGCGGAACTCGGTGG	NPRL3	ENSG00000103148	0.11920319230513468	[127,64]	[54,14]	1	dCas9-VP64	positive selection	2488100
138803	138826	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGCCGTACGGTTCGCGTTTGG	NPRL3	ENSG00000103148	1.517540028608139	[55,44]	[30,62]	8	dCas9-VP64	positive selection	2488101
124982	125005	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATCGCTTGAACCCTAG	NPRL3	ENSG00000103148	1.2597172262171965	[381,372]	[459,141]	7	dCas9-VP64	positive selection	2545303
131132	131155	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGAAACCAGCCTGGCCAACATGG	NPRL3	ENSG00000103148	0.26160550637758195	[116,79]	[45,30]	2	dCas9-VP64	positive selection	2568165
92712	92735	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-1.3829187247765107	[398,398]	[0,0]	-8	hSpCas9	positive selection	3382238
112700	112723	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.5430806937797126	[104,104]	[0,0]	2	hSpCas9	positive selection	3382239
92613	92636	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	-2.030386168103614	[624,624]	[0,0]	-9	hSpCas9	positive selection	3382240
110524	110547	16	-	26780180	A375	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	1.58165994321535	[]	[]	8	hSpCas9	negative selection	3973458
138231	138254	16	-	26780180	A375	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.508971894220397	[]	[]	1	hSpCas9	negative selection	3973459
112700	112723	16	-	26780180	A375	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.678071750077437	[]	[]	2	hSpCas9	negative selection	3973460
92613	92636	16	-	26780180	A375	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	1.32096955437471	[]	[]	7	hSpCas9	negative selection	3973461
92712	92735	16	-	26780180	A375	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	1.83303243030057	[]	[]	9	hSpCas9	negative selection	3973462
138255	138278	16	+	26780180	A375	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	0.775500715250664	[]	[]	3	hSpCas9	negative selection	3973463
110524	110547	16	-	26780180	HT29	viability (GeCKOv2 library)	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	2.39543147477178	[]	[]	9	hSpCas9	negative selection	4081424
138231	138254	16	-	26780180	HT29	viability (GeCKOv2 library)	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.51230114841604	[]	[]	1	hSpCas9	negative selection	4081425
112700	112723	16	-	26780180	HT29	viability (GeCKOv2 library)	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.555145189963585	[]	[]	1	hSpCas9	negative selection	4081426
92613	92636	16	-	26780180	HT29	viability (GeCKOv2 library)	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	1.40541639905214	[]	[]	7	hSpCas9	negative selection	4081427
92712	92735	16	-	26780180	HT29	viability (GeCKOv2 library)	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	2.04161498407206	[]	[]	9	hSpCas9	negative selection	4081428
138255	138278	16	+	26780180	HT29	viability (GeCKOv2 library)	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	0.68348235083351	[]	[]	2	hSpCas9	negative selection	4081429
85698	85721	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACCCCTCCGCTTCTATGTCCGG	NPRL3	ENSG00000103148	0.5173773585951313	[4]	[6,2]	9	hSpCas9	positive selection	4152522
85411	85434	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.3809804641247434	[3]	[2,3]	8	hSpCas9	positive selection	4152528
85698	85721	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACCCCTCCGCTTCTATGTCCGG	NPRL3	ENSG00000103148	0.6785614686606138	[2]	[4,1,3,0]	4	hSpCas9	positive selection	4216544
85411	85434	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.15887672853280488	[4]	[4,2,1,0]	1	hSpCas9	positive selection	4216550
85504	85527	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	0.3440265608939276	[2]	[2,1]	7	hSpCas9	positive selection	4283380
85411	85434	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.3026657325772894	[1]	[1,1]	6	hSpCas9	positive selection	4283381
138255	138278	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.2624046150175572	[1]	[0,0]	-5	hSpCas9	positive selection	4286175
138231	138254	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.33681645176926367	[4]	[4,4]	6	hSpCas9	positive selection	4286176
110524	110547	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	-0.06283714947707264	[3]	[2,2]	-1	hSpCas9	positive selection	4286177
92712	92735	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.26152691782590237	[3]	[2,1]	-5	hSpCas9	positive selection	4350432
112700	112723	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.5695127794404142	[1]	[2,1]	9	hSpCas9	positive selection	4350433
92613	92636	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.06117490594104047	[3]	[3,2]	1	hSpCas9	positive selection	4350434
138598	138621	16	+	27661255	K562	viability	GACAGGGGTGGTGGTGGACGCGG	NPRL3	ENSG00000103148	0.12453405843849483	[735,685]	[701,549]	4	dCas9-KRAB	negative selection	5497286
138666	138689	16	+	27661255	K562	viability	GAGACTTCGGCGACACCGTCCGG	NPRL3	ENSG00000103148	0.16958151927532816	[903,1134]	[976,856]	6	dCas9-KRAB	negative selection	5497287
138628	138651	16	-	27661255	K562	viability	GGCACGTGGGTTGGTAACTGTGG	NPRL3	ENSG00000103148	0.1378174198757356	[662,540]	[584,484]	5	dCas9-KRAB	negative selection	5497288
138641	138664	16	-	27661255	K562	viability	GAGCCCGGAGCGTGGCACGTGGG	NPRL3	ENSG00000103148	0.27513515718696513	[640,589]	[624,570]	8	dCas9-KRAB	negative selection	5497289
138681	138704	16	-	27661255	K562	viability	GCCTTAGCACCTCCTCCGGACGG	NPRL3	ENSG00000103148	0.3643929776978243	[231,187]	[219,213]	9	dCas9-KRAB	negative selection	5497290
85504	85527	16	-	27260156	BXPC3	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	0.05367078118115842	[253]	[213,276,353,261]	1	hSpCas9	negative selection	5555840
85411	85434	16	+	27260156	BXPC3	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.3860852846262961	[155]	[254,166,166,265]	8	hSpCas9	negative selection	5555841
138255	138278	16	+	27260156	BXPC3	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.16601597295733939	[77]	[92,76,62,51]	-4	hSpCas9	negative selection	5558635
138231	138254	16	-	27260156	BXPC3	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.24079402312964882	[1269]	[1453,1454,1512,1902]	5	hSpCas9	negative selection	5558636
110524	110547	16	-	27260156	BXPC3	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	-0.14337557179521754	[760]	[757,591,659,889]	-3	hSpCas9	negative selection	5558637
92712	92735	16	-	27260156	BXPC3	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.054012030747690676	[711]	[655,549,790,907]	-1	hSpCas9	negative selection	5622892
112700	112723	16	-	27260156	BXPC3	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.427721361673955	[144]	[173,158,240,252]	8	hSpCas9	negative selection	5622893
92613	92636	16	-	27260156	BXPC3	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.25348918390619246	[918]	[1034,958,1319,1305]	5	hSpCas9	negative selection	5622894
85504	85527	16	-	27260156	A673	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	0.14015177280871016	[253]	[355,286,411,288]	3	hSpCas9	negative selection	5677091
85411	85434	16	+	27260156	A673	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.0013061340370088548	[155]	[158,245,94,248]	0	hSpCas9	negative selection	5677092
138255	138278	16	+	27260156	A673	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.12724414716086452	[77]	[58,86,85,108]	-3	hSpCas9	negative selection	5679886
138231	138254	16	-	27260156	A673	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.5370646929395042	[1269]	[2208,2315,2181,2131]	9	hSpCas9	negative selection	5679887
110524	110547	16	-	27260156	A673	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.07946962189476814	[760]	[1060,1031,895,875]	2	hSpCas9	negative selection	5679888
92712	92735	16	-	27260156	A673	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.14021190927827032	[711]	[1151,780,926,934]	3	hSpCas9	negative selection	5744143
112700	112723	16	-	27260156	A673	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.4764075140200521	[144]	[222,238,248,255]	9	hSpCas9	negative selection	5744144
92613	92636	16	-	27260156	A673	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.3502258919617026	[918]	[1517,1315,1370,1435]	7	hSpCas9	negative selection	5744145
85504	85527	16	-	27260156	A375	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.2120693767692734	[253]	[270,410,179,190]	-3	hSpCas9	negative selection	5798342
85411	85434	16	+	27260156	A375	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.9467127782864652	[155]	[308,274,470,338]	9	hSpCas9	negative selection	5798343
138255	138278	16	+	27260156	A375	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-1.2217628653958656	[77]	[29,11,77,32]	-8	hSpCas9	negative selection	5801137
138231	138254	16	-	27260156	A375	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.662207507407329	[1269]	[2461,2544,1982,2410]	8	hSpCas9	negative selection	5801138
110524	110547	16	-	27260156	A375	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.03592607897641409	[760]	[891,1137,686,950]	0	hSpCas9	negative selection	5801139
92712	92735	16	-	27260156	A375	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.5138768210708203	[711]	[567,869,510,435]	-6	hSpCas9	negative selection	5865394
112700	112723	16	-	27260156	A375	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.21949751184331756	[144]	[198,157,250,176]	3	hSpCas9	negative selection	5865395
92613	92636	16	-	27260156	A375	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.3010728784175839	[918]	[1377,1591,1153,1211]	4	hSpCas9	negative selection	5865396
85504	85527	16	-	27260156	COLO741	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	0.11568563778205687	[253]	[294,368,382]	2	hSpCas9	negative selection	5919593
85411	85434	16	+	27260156	COLO741	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.5644425964312496	[155]	[373,218,296]	9	hSpCas9	negative selection	5919594
138255	138278	16	+	27260156	COLO741	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.5518135720634816	[77]	[74,69,59]	-8	hSpCas9	negative selection	5922388
138231	138254	16	-	27260156	COLO741	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.4233471935829427	[1269]	[2527,2245,1806]	8	hSpCas9	negative selection	5922389
110524	110547	16	-	27260156	COLO741	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.10367369262194015	[760]	[1179,1110,865]	2	hSpCas9	negative selection	5922390
92712	92735	16	-	27260156	COLO741	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.13427671142859643	[711]	[823,909,755]	-3	hSpCas9	negative selection	5986645
112700	112723	16	-	27260156	COLO741	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.7395216199289985	[144]	[376,289,268]	9	hSpCas9	negative selection	5986646
92613	92636	16	-	27260156	COLO741	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.21882375018565414	[918]	[1381,1365,1350]	4	hSpCas9	negative selection	5986647
85504	85527	16	-	27260156	CAL120	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.369747429602165	[253]	[299,248,193]	-5	hSpCas9	negative selection	6040844
85411	85434	16	+	27260156	CAL120	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.36931585516724574	[155]	[293,231,232]	5	hSpCas9	negative selection	6040845
138255	138278	16	+	27260156	CAL120	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	0.23013948805158835	[77]	[136,150,57]	3	hSpCas9	negative selection	6043639
138231	138254	16	-	27260156	CAL120	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.5223270166803207	[1269]	[2336,2564,1922]	7	hSpCas9	negative selection	6043640
110524	110547	16	-	27260156	CAL120	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.4593922190961687	[760]	[1487,1220,1225]	7	hSpCas9	negative selection	6043641
92712	92735	16	-	27260156	CAL120	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.07506422086403997	[711]	[1080,692,785]	-1	hSpCas9	negative selection	6107896
112700	112723	16	-	27260156	CAL120	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.5118569616840716	[144]	[323,268,189]	7	hSpCas9	negative selection	6107897
92613	92636	16	-	27260156	CAL120	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.5402078906060878	[918]	[2612,954,1564]	7	hSpCas9	negative selection	6107898
85504	85527	16	-	27260156	CADOES1	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.2234035280850344	[253]	[129,222,192,265]	-4	hSpCas9	negative selection	6162095
85411	85434	16	+	27260156	CADOES1	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.8215699523517082	[155]	[176,307,385,150]	9	hSpCas9	negative selection	6162096
138255	138278	16	+	27260156	CADOES1	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.7115021879889776	[77]	[34,31,70,38]	-8	hSpCas9	negative selection	6164890
138231	138254	16	-	27260156	CADOES1	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.8248311586015293	[1269]	[1858,2235,2076,2201]	9	hSpCas9	negative selection	6164891
110524	110547	16	-	27260156	CADOES1	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.15463681647091054	[760]	[573,1188,724,659]	2	hSpCas9	negative selection	6164892
92712	92735	16	-	27260156	CADOES1	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.6200908256131424	[711]	[1087,1359,1032,573]	8	hSpCas9	negative selection	6229147
112700	112723	16	-	27260156	CADOES1	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.0816919039214481	[144]	[117,116,214,119]	1	hSpCas9	negative selection	6229148
92613	92636	16	-	27260156	CADOES1	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.4032045370104852	[918]	[1268,1090,950,1212]	6	hSpCas9	negative selection	6229149
85504	85527	16	-	27260156	EWS502	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.127134457843469	[253]	[233,228,213,313]	-2	hSpCas9	negative selection	6283346
85411	85434	16	+	27260156	EWS502	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.11450100161692323	[155]	[204,196,132,174]	2	hSpCas9	negative selection	6283347
138255	138278	16	+	27260156	EWS502	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	0.14662270703330282	[77]	[68,123,93,78]	2	hSpCas9	negative selection	6286141
138231	138254	16	-	27260156	EWS502	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.9308371854448656	[1269]	[2411,2669,2751,2419]	9	hSpCas9	negative selection	6286142
110524	110547	16	-	27260156	EWS502	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.3051009765156155	[760]	[856,914,1010,1233]	5	hSpCas9	negative selection	6286143
92712	92735	16	-	27260156	EWS502	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.44604760686446887	[711]	[967,1063,1011,1069]	7	hSpCas9	negative selection	6350398
112700	112723	16	-	27260156	EWS502	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.6394405538375125	[144]	[225,256,247,224]	9	hSpCas9	negative selection	6350399
92613	92636	16	-	27260156	EWS502	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.8011059290647679	[918]	[1695,1637,1939,1494]	9	hSpCas9	negative selection	6350400
85504	85527	16	-	27260156	EW8	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.2692253751706579	[253]	[195,188,144,159]	-5	hSpCas9	negative selection	6404597
85411	85434	16	+	27260156	EW8	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.6210964099870313	[155]	[230,290,140,127]	9	hSpCas9	negative selection	6404598
138255	138278	16	+	27260156	EW8	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	0.1763182746639007	[77]	[94,39,28,130]	3	hSpCas9	negative selection	6407392
138231	138254	16	-	27260156	EW8	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.4826290884293738	[1269]	[1619,1585,1227,1370]	8	hSpCas9	negative selection	6407393
110524	110547	16	-	27260156	EW8	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.02003820048409799	[760]	[586,714,618,575]	0	hSpCas9	negative selection	6407394
92712	92735	16	-	27260156	EW8	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.2217028601193164	[711]	[649,795,665,576]	4	hSpCas9	negative selection	6471649
112700	112723	16	-	27260156	EW8	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.6220186087963788	[144]	[255,201,165,109]	9	hSpCas9	negative selection	6471650
92613	92636	16	-	27260156	EW8	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.15246295820343747	[918]	[934,982,713,708]	3	hSpCas9	negative selection	6471651
85504	85527	16	-	27260156	CORL105	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.5014511454552193	[253]	[232,201,227,180]	-7	hSpCas9	negative selection	6525848
85411	85434	16	+	27260156	CORL105	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.4283256540012146	[155]	[299,220,261,204]	7	hSpCas9	negative selection	6525849
138255	138278	16	+	27260156	CORL105	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.0344960937894756	[77]	[86,78,59,125]	0	hSpCas9	negative selection	6528643
138231	138254	16	-	27260156	CORL105	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.38828854474732344	[1269]	[1677,1694,2166,2271]	7	hSpCas9	negative selection	6528644
110524	110547	16	-	27260156	CORL105	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.25946213771467286	[760]	[993,844,1322,1144]	5	hSpCas9	negative selection	6528645
92712	92735	16	-	27260156	CORL105	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.03529707002765148	[711]	[649,885,1128,786]	0	hSpCas9	negative selection	6592900
112700	112723	16	-	27260156	CORL105	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.4411021104107591	[144]	[130,150,241,396]	7	hSpCas9	negative selection	6592901
92613	92636	16	-	27260156	CORL105	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.14916666024611447	[918]	[1279,940,1392,1196]	3	hSpCas9	negative selection	6592902
85504	85527	16	-	27260156	HS294T	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.49465986705257614	[253]	[46,93,68,69]	-6	hSpCas9	negative selection	6647099
85411	85434	16	+	27260156	HS294T	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	1.2948568329633356	[155]	[111,69,165,269]	9	hSpCas9	negative selection	6647100
138255	138278	16	+	27260156	HS294T	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.8207804262905207	[77]	[15,16,19,14]	-8	hSpCas9	negative selection	6649894
138231	138254	16	-	27260156	HS294T	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.8409308153029098	[1269]	[1334,756,668,680]	9	hSpCas9	negative selection	6649895
110524	110547	16	-	27260156	HS294T	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	-0.003263889768750694	[760]	[303,313,257,295]	0	hSpCas9	negative selection	6649896
92712	92735	16	-	27260156	HS294T	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.06584093993256623	[711]	[319,212,192,332]	-1	hSpCas9	negative selection	6714151
112700	112723	16	-	27260156	HS294T	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.6994525337209465	[144]	[96,156,55,42]	8	hSpCas9	negative selection	6714152
92613	92636	16	-	27260156	HS294T	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.38381199637061825	[918]	[359,428,477,623]	5	hSpCas9	negative selection	6714153
85504	85527	16	-	27260156	HCC44	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	0.17729388389919254	[253]	[201,321,373,393]	3	hSpCas9	negative selection	6768350
85411	85434	16	+	27260156	HCC44	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.03361785807111506	[155]	[54,234,310,124]	0	hSpCas9	negative selection	6768351
138255	138278	16	+	27260156	HCC44	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.20486245254236524	[77]	[15,122,89,66]	-3	hSpCas9	negative selection	6771145
138231	138254	16	-	27260156	HCC44	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.6064002725296103	[1269]	[2146,1900,2677,2126]	8	hSpCas9	negative selection	6771146
110524	110547	16	-	27260156	HCC44	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	-0.07911638191713966	[760]	[843,577,994,899]	-1	hSpCas9	negative selection	6771147
92712	92735	16	-	27260156	HCC44	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.38616541615547806	[711]	[677,498,813,527]	-6	hSpCas9	negative selection	6835402
112700	112723	16	-	27260156	HCC44	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.7238820908411244	[144]	[580,122,258,168]	9	hSpCas9	negative selection	6835403
92613	92636	16	-	27260156	HCC44	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.3868436771052398	[918]	[1185,1260,1761,1285]	6	hSpCas9	negative selection	6835404
85504	85527	16	-	27260156	G402	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-1.304887954940805	[253]	[102,123,124,144]	-9	hSpCas9	negative selection	6889601
85411	85434	16	+	27260156	G402	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.46172397296274026	[155]	[258,417,91,285]	6	hSpCas9	negative selection	6889602
138255	138278	16	+	27260156	G402	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.4705562235864047	[77]	[35,53,90,86]	-5	hSpCas9	negative selection	6892396
138231	138254	16	-	27260156	G402	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.2924051673981074	[1269]	[2822,1612,1345,1917]	3	hSpCas9	negative selection	6892397
110524	110547	16	-	27260156	G402	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	-0.09740763168719035	[760]	[1078,592,414,1370]	-1	hSpCas9	negative selection	6892398
92712	92735	16	-	27260156	G402	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.48286283554273157	[711]	[1006,766,399,385]	-6	hSpCas9	negative selection	6956653
112700	112723	16	-	27260156	G402	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.300848613523355	[144]	[343,149,210,181]	4	hSpCas9	negative selection	6956654
92613	92636	16	-	27260156	G402	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.2384129317065763	[918]	[1331,1384,1139,1428]	3	hSpCas9	negative selection	6956655
85504	85527	16	-	27260156	L33	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.06833416808396231	[253]	[180,86,194,266]	-1	hSpCas9	negative selection	7010852
85411	85434	16	+	27260156	L33	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	-0.05779684493501347	[155]	[137,114,59,85]	-1	hSpCas9	negative selection	7010853
138255	138278	16	+	27260156	L33	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.016764804626249852	[77]	[48,30,80,55]	0	hSpCas9	negative selection	7013647
138231	138254	16	-	27260156	L33	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.2841134130146963	[1269]	[1481,608,1054,1540]	6	hSpCas9	negative selection	7013648
110524	110547	16	-	27260156	L33	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.11806413576230645	[760]	[801,337,499,880]	2	hSpCas9	negative selection	7013649
92712	92735	16	-	27260156	L33	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.03772969022774486	[711]	[743,272,502,712]	0	hSpCas9	negative selection	7077904
112700	112723	16	-	27260156	L33	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.5731286765723715	[144]	[277,89,105,194]	9	hSpCas9	negative selection	7077905
92613	92636	16	-	27260156	L33	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.3216568689943008	[918]	[1169,502,730,1033]	6	hSpCas9	negative selection	7077906
85504	85527	16	-	27260156	K562	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.5752579349950997	[253]	[197,111,151,144]	-6	hSpCas9	negative selection	7132103
85411	85434	16	+	27260156	K562	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.449100386151255	[155]	[106,300,172,174]	6	hSpCas9	negative selection	7132104
138255	138278	16	+	27260156	K562	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.15238487888988717	[77]	[136,36,48,33]	-2	hSpCas9	negative selection	7134898
138231	138254	16	-	27260156	K562	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.2724083811291065	[1269]	[1260,1657,1358,1188]	3	hSpCas9	negative selection	7134899
110524	110547	16	-	27260156	K562	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	-0.6116055693938395	[760]	[613,576,321,291]	-6	hSpCas9	negative selection	7134900
92712	92735	16	-	27260156	K562	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.5536775379949626	[711]	[634,405,117,560]	-6	hSpCas9	negative selection	7199155
112700	112723	16	-	27260156	K562	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.15848290192430903	[144]	[162,188,130,99]	2	hSpCas9	negative selection	7199156
92613	92636	16	-	27260156	K562	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	-0.1059231483673212	[918]	[767,1192,646,476]	-1	hSpCas9	negative selection	7199157
85504	85527	16	-	27260156	HT29	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.08133427142198313	[253]	[370,232,294,269]	-2	hSpCas9	negative selection	7253354
85411	85434	16	+	27260156	HT29	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.2539900513252302	[155]	[305,271,126,209]	5	hSpCas9	negative selection	7253355
138255	138278	16	+	27260156	HT29	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	0.7051481173577989	[77]	[102,243,164,113]	9	hSpCas9	negative selection	7256149
138231	138254	16	-	27260156	HT29	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.32111458035940954	[1269]	[1770,2370,2009,1613]	6	hSpCas9	negative selection	7256150
110524	110547	16	-	27260156	HT29	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.07029923019958462	[760]	[1088,1048,813,944]	1	hSpCas9	negative selection	7256151
92712	92735	16	-	27260156	HT29	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.05001740869198168	[711]	[974,828,958,823]	0	hSpCas9	negative selection	7320406
112700	112723	16	-	27260156	HT29	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.43480155059368664	[144]	[183,330,218,222]	8	hSpCas9	negative selection	7320407
92613	92636	16	-	27260156	HT29	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.3328511577833807	[918]	[1689,1629,1193,1173]	6	hSpCas9	negative selection	7320408
85504	85527	16	-	27260156	MHHES1	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	0.20431733509072514	[253]	[318,353,527,153]	4	hSpCas9	negative selection	7374605
85411	85434	16	+	27260156	MHHES1	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	-0.012425621729025504	[155]	[181,186,177,152]	0	hSpCas9	negative selection	7374606
138255	138278	16	+	27260156	MHHES1	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	0.815089406731474	[77]	[341,44,206,55]	9	hSpCas9	negative selection	7377400
138231	138254	16	-	27260156	MHHES1	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	1.0861624714386533	[1269]	[3260,3758,2779,2501]	9	hSpCas9	negative selection	7377401
110524	110547	16	-	27260156	MHHES1	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.6349586924641558	[760]	[1490,1263,1660,975]	9	hSpCas9	negative selection	7377402
92712	92735	16	-	27260156	MHHES1	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.8424356206435454	[711]	[1219,1468,1378,1589]	9	hSpCas9	negative selection	7441657
112700	112723	16	-	27260156	MHHES1	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.6653737452517117	[144]	[317,220,259,238]	9	hSpCas9	negative selection	7441658
92613	92636	16	-	27260156	MHHES1	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	1.0065852239326771	[918]	[2181,2722,1967,1589]	9	hSpCas9	negative selection	7441659
85504	85527	16	-	27260156	MEWO	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.10754845717088724	[253]	[215,169,274]	-2	hSpCas9	negative selection	7495856
85411	85434	16	+	27260156	MEWO	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.28874583172985746	[155]	[219,157,164]	6	hSpCas9	negative selection	7495857
138255	138278	16	+	27260156	MEWO	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.07084208452561391	[77]	[46,81,74]	-1	hSpCas9	negative selection	7498651
138231	138254	16	-	27260156	MEWO	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.37571192144032906	[1269]	[1726,1628,1303]	7	hSpCas9	negative selection	7498652
110524	110547	16	-	27260156	MEWO	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.27234817754126694	[760]	[836,867,869]	6	hSpCas9	negative selection	7498653
92712	92735	16	-	27260156	MEWO	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.21525237849906176	[711]	[862,796,676]	5	hSpCas9	negative selection	7562908
112700	112723	16	-	27260156	MEWO	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.024701433814677376	[144]	[106,129,170]	0	hSpCas9	negative selection	7562909
92613	92636	16	-	27260156	MEWO	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.24621295382772745	[918]	[1295,736,1080]	5	hSpCas9	negative selection	7562910
85504	85527	16	-	27260156	LNCAPCLONEFGC	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.17125594916341513	[253]	[283,181,216,135]	-3	hSpCas9	negative selection	7617107
85411	85434	16	+	27260156	LNCAPCLONEFGC	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.591119925077648	[155]	[113,266,288,190]	8	hSpCas9	negative selection	7617108
138255	138278	16	+	27260156	LNCAPCLONEFGC	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.20792077381371188	[77]	[55,66,24,90]	-3	hSpCas9	negative selection	7619902
138231	138254	16	-	27260156	LNCAPCLONEFGC	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.4542141403457185	[1269]	[1498,1449,1701,1680]	7	hSpCas9	negative selection	7619903
110524	110547	16	-	27260156	LNCAPCLONEFGC	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.1115823647626144	[760]	[678,726,642,916]	1	hSpCas9	negative selection	7619904
92712	92735	16	-	27260156	LNCAPCLONEFGC	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.4386226197157868	[711]	[439,435,451,574]	-6	hSpCas9	negative selection	7684159
112700	112723	16	-	27260156	LNCAPCLONEFGC	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.5259828887698148	[144]	[162,202,168,217]	8	hSpCas9	negative selection	7684160
92613	92636	16	-	27260156	LNCAPCLONEFGC	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.21809012720723586	[918]	[884,884,1346,818]	3	hSpCas9	negative selection	7684161
85504	85527	16	-	27260156	PANC0327	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	0.18126169678896842	[253]	[320,120,273,329]	2	hSpCas9	negative selection	7738358
85411	85434	16	+	27260156	PANC0327	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.461957621891419	[155]	[201,200,162,196]	6	hSpCas9	negative selection	7738359
138255	138278	16	+	27260156	PANC0327	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	0.09185953011772563	[77]	[55,33,77,130]	1	hSpCas9	negative selection	7741153
138231	138254	16	-	27260156	PANC0327	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.2762508782001436	[1269]	[1509,1280,1211,1483]	4	hSpCas9	negative selection	7741154
110524	110547	16	-	27260156	PANC0327	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.08275119872407877	[760]	[444,982,813,564]	1	hSpCas9	negative selection	7741155
92712	92735	16	-	27260156	PANC0327	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.7184595917826572	[711]	[351,269,626,300]	-7	hSpCas9	negative selection	7805410
112700	112723	16	-	27260156	PANC0327	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	-0.4258470334971274	[144]	[121,92,83,86]	-6	hSpCas9	negative selection	7805411
92613	92636	16	-	27260156	PANC0327	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.07863778144539124	[918]	[734,816,701,1188]	1	hSpCas9	negative selection	7805412
85504	85527	16	-	27260156	NCIH2009	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.06388020107194625	[253]	[478,367,197]	-1	hSpCas9	negative selection	7859609
85411	85434	16	+	27260156	NCIH2009	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.24975523350033035	[155]	[199,331,231]	3	hSpCas9	negative selection	7859610
138255	138278	16	+	27260156	NCIH2009	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.6785143032973688	[77]	[134,33,48]	-7	hSpCas9	negative selection	7862404
138231	138254	16	-	27260156	NCIH2009	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.3915038333553664	[1269]	[2742,2375,1940]	5	hSpCas9	negative selection	7862405
110524	110547	16	-	27260156	NCIH2009	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.07622514885217857	[760]	[1364,1126,916]	1	hSpCas9	negative selection	7862406
92712	92735	16	-	27260156	NCIH2009	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.19310728492292828	[711]	[1760,922,852]	2	hSpCas9	negative selection	7926661
112700	112723	16	-	27260156	NCIH2009	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.31888070458367146	[144]	[196,178,371]	4	hSpCas9	negative selection	7926662
92613	92636	16	-	27260156	NCIH2009	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.4366115666038507	[918]	[1999,1583,1680]	6	hSpCas9	negative selection	7926663
85504	85527	16	-	27260156	NCIH1373	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.052308693971993	[253]	[307,251,140,108]	0	hSpCas9	negative selection	7980860
85411	85434	16	+	27260156	NCIH1373	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.6971231992266876	[155]	[359,201,196,105]	7	hSpCas9	negative selection	7980861
138255	138278	16	+	27260156	NCIH1373	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-1.0122886269748155	[77]	[123,27,18,3]	-8	hSpCas9	negative selection	7983655
138231	138254	16	-	27260156	NCIH1373	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.653972739253144	[1269]	[3180,1836,2106,525]	6	hSpCas9	negative selection	7983656
110524	110547	16	-	27260156	NCIH1373	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.292259301391947	[760]	[930,1414,1025,189]	3	hSpCas9	negative selection	7983657
92712	92735	16	-	27260156	NCIH1373	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.12016594535228575	[711]	[847,952,879,200]	1	hSpCas9	negative selection	8047912
112700	112723	16	-	27260156	NCIH1373	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.035243671511540065	[144]	[385,85,105,33]	0	hSpCas9	negative selection	8047913
92613	92636	16	-	27260156	NCIH1373	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.3883420780674519	[918]	[1547,1113,1616,300]	4	hSpCas9	negative selection	8047914
85504	85527	16	-	27260156	PATU8902	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.2810735831460387	[253]	[96,281,495,228]	-3	hSpCas9	negative selection	8102111
85411	85434	16	+	27260156	PATU8902	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.6117594376479913	[155]	[221,503,312,287]	6	hSpCas9	negative selection	8102112
138255	138278	16	+	27260156	PATU8902	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	0.3796151011869542	[77]	[44,82,83,398]	4	hSpCas9	negative selection	8104906
138231	138254	16	-	27260156	PATU8902	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.7486783960226266	[1269]	[3056,3365,1657,4280]	7	hSpCas9	negative selection	8104907
110524	110547	16	-	27260156	PATU8902	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.23160086455565831	[760]	[1774,864,1105,1249]	2	hSpCas9	negative selection	8104908
92712	92735	16	-	27260156	PATU8902	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.06301822318627526	[711]	[1067,719,1098,848]	0	hSpCas9	negative selection	8169163
112700	112723	16	-	27260156	PATU8902	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	1.0086227544588229	[144]	[417,378,529,242]	9	hSpCas9	negative selection	8169164
92613	92636	16	-	27260156	PATU8902	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.35231494990789847	[918]	[2480,1321,1065,1809]	3	hSpCas9	negative selection	8169165
85504	85527	16	-	27260156	PANC1	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	0.1309829054530477	[253]	[240,267,220,228]	2	hSpCas9	negative selection	8223362
85411	85434	16	+	27260156	PANC1	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	-0.1566619994050804	[155]	[90,161,114,119]	-3	hSpCas9	negative selection	8223363
138255	138278	16	+	27260156	PANC1	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.761559531951784	[77]	[61,18,60,14]	-8	hSpCas9	negative selection	8226157
138231	138254	16	-	27260156	PANC1	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.4631112936906481	[1269]	[1479,1971,1536,1155]	7	hSpCas9	negative selection	8226158
110524	110547	16	-	27260156	PANC1	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.3252587543842508	[760]	[614,996,816,865]	5	hSpCas9	negative selection	8226159
92712	92735	16	-	27260156	PANC1	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.015744510542266776	[711]	[614,638,536,666]	0	hSpCas9	negative selection	8290414
112700	112723	16	-	27260156	PANC1	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.8957490177746036	[144]	[237,184,268,222]	9	hSpCas9	negative selection	8290415
92613	92636	16	-	27260156	PANC1	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.23922693132594997	[918]	[1179,805,784,910]	4	hSpCas9	negative selection	8290416
85504	85527	16	-	27260156	PANC0813	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	0.28713518869307897	[253]	[438,214,546,267]	4	hSpCas9	negative selection	8344613
85411	85434	16	+	27260156	PANC0813	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.23976259893319618	[155]	[253,164,237,211]	4	hSpCas9	negative selection	8344614
138255	138278	16	+	27260156	PANC0813	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	0.20151733082105094	[77]	[83,142,83,107]	3	hSpCas9	negative selection	8347408
138231	138254	16	-	27260156	PANC0813	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.42808022871074614	[1269]	[2082,1905,2029,2012]	7	hSpCas9	negative selection	8347409
110524	110547	16	-	27260156	PANC0813	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.3547111718523154	[760]	[969,1296,1568,742]	6	hSpCas9	negative selection	8347410
92712	92735	16	-	27260156	PANC0813	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.0898446995545058	[711]	[780,618,843,891]	-1	hSpCas9	negative selection	8411665
112700	112723	16	-	27260156	PANC0813	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.4994753695308298	[144]	[235,262,321,146]	7	hSpCas9	negative selection	8411666
92613	92636	16	-	27260156	PANC0813	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.4089819262549924	[918]	[1422,1421,1280,1593]	6	hSpCas9	negative selection	8411667
85504	85527	16	-	27260156	RDES	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.09020142589504421	[253]	[225,229,311,348]	-1	hSpCas9	negative selection	8465864
85411	85434	16	+	27260156	RDES	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.8435109485264282	[155]	[286,371,338,274]	9	hSpCas9	negative selection	8465865
138255	138278	16	+	27260156	RDES	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.2763457732287433	[77]	[74,29,96,100]	-5	hSpCas9	negative selection	8468659
138231	138254	16	-	27260156	RDES	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.5011076544190796	[1269]	[1706,1820,2353,2502]	7	hSpCas9	negative selection	8468660
110524	110547	16	-	27260156	RDES	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.1772177001907954	[760]	[832,876,1061,1241]	3	hSpCas9	negative selection	8468661
92712	92735	16	-	27260156	RDES	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.02952047790493728	[711]	[808,798,951,755]	0	hSpCas9	negative selection	8532916
112700	112723	16	-	27260156	RDES	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.7935495417928667	[144]	[212,283,390,278]	9	hSpCas9	negative selection	8532917
92613	92636	16	-	27260156	RDES	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.4695338056072672	[918]	[1203,1427,1396,1903]	7	hSpCas9	negative selection	8532918
85504	85527	16	-	27260156	PC3	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	0.06086844567408034	[253]	[163,172,491,343]	1	hSpCas9	negative selection	8587115
85411	85434	16	+	27260156	PC3	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.5240541992367476	[155]	[206,87,329,298]	9	hSpCas9	negative selection	8587116
138255	138278	16	+	27260156	PC3	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	0.2927436532447967	[77]	[131,77,34,76]	6	hSpCas9	negative selection	8589910
138231	138254	16	-	27260156	PC3	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.45350154448588964	[1269]	[843,1974,2621,2092]	8	hSpCas9	negative selection	8589911
110524	110547	16	-	27260156	PC3	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.08272982770696313	[760]	[432,708,1380,1024]	1	hSpCas9	negative selection	8589912
92712	92735	16	-	27260156	PC3	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.35290344611866864	[711]	[742,714,1419,918]	7	hSpCas9	negative selection	8654167
112700	112723	16	-	27260156	PC3	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.3711121665445818	[144]	[136,132,324,211]	7	hSpCas9	negative selection	8654168
92613	92636	16	-	27260156	PC3	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.5189728390350649	[918]	[788,1311,1970,1550]	9	hSpCas9	negative selection	8654169
85504	85527	16	-	27260156	PATU8988T	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.055313636554606416	[253]	[165,201,161,427]	-1	hSpCas9	negative selection	8708366
85411	85434	16	+	27260156	PATU8988T	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.7275046886592077	[155]	[309,270,223,190]	9	hSpCas9	negative selection	8708367
138255	138278	16	+	27260156	PATU8988T	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.13395520668335337	[77]	[115,72,45,37]	-2	hSpCas9	negative selection	8711161
138231	138254	16	-	27260156	PATU8988T	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.3592130710682375	[1269]	[1343,1728,1345,1922]	6	hSpCas9	negative selection	8711162
110524	110547	16	-	27260156	PATU8988T	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.22233054874771896	[760]	[918,867,790,854]	4	hSpCas9	negative selection	8711163
92712	92735	16	-	27260156	PATU8988T	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.07790895519752117	[711]	[695,804,758,644]	1	hSpCas9	negative selection	8775418
112700	112723	16	-	27260156	PATU8988T	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.42011455949716137	[144]	[206,201,112,233]	7	hSpCas9	negative selection	8775419
92613	92636	16	-	27260156	PATU8988T	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.35856223677473376	[918]	[984,1736,866,1014]	6	hSpCas9	negative selection	8775420
85504	85527	16	-	27260156	T47D	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.14842478956705496	[253]	[310,249,279,226]	-3	hSpCas9	negative selection	8829617
85411	85434	16	+	27260156	T47D	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.2565476692202888	[155]	[282,168,163,258]	5	hSpCas9	negative selection	8829618
138255	138278	16	+	27260156	T47D	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.08718556875160166	[77]	[60,91,65,123]	-2	hSpCas9	negative selection	8832412
138231	138254	16	-	27260156	T47D	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.4667451267421818	[1269]	[2206,1865,2214,1898]	8	hSpCas9	negative selection	8832413
110524	110547	16	-	27260156	T47D	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.16237089181802566	[760]	[1023,936,1076,931]	3	hSpCas9	negative selection	8832414
92712	92735	16	-	27260156	T47D	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.10637049300206053	[711]	[674,756,773,879]	-2	hSpCas9	negative selection	8896669
112700	112723	16	-	27260156	T47D	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.19659666021173017	[144]	[175,196,220,178]	4	hSpCas9	negative selection	8896670
92613	92636	16	-	27260156	T47D	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.31952701601487077	[918]	[1564,1133,1417,1240]	6	hSpCas9	negative selection	8896671
85504	85527	16	-	27260156	SU8686	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	0.040330142839595684	[253]	[351,239,254,162]	0	hSpCas9	negative selection	8950868
85411	85434	16	+	27260156	SU8686	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.373982836457762	[155]	[196,240,155,199]	6	hSpCas9	negative selection	8950869
138255	138278	16	+	27260156	SU8686	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.3095745116133517	[77]	[42,60,61,89]	-5	hSpCas9	negative selection	8953663
138231	138254	16	-	27260156	SU8686	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.3303013248500628	[1269]	[1193,1443,1908,1895]	5	hSpCas9	negative selection	8953664
110524	110547	16	-	27260156	SU8686	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	-0.035205503412653605	[760]	[553,714,930,774]	0	hSpCas9	negative selection	8953665
92712	92735	16	-	27260156	SU8686	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.23937692088902618	[711]	[782,619,1019,963]	4	hSpCas9	negative selection	9017920
112700	112723	16	-	27260156	SU8686	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	-0.010368243929270715	[144]	[90,170,147,165]	0	hSpCas9	negative selection	9017921
92613	92636	16	-	27260156	SU8686	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.48369563602377685	[918]	[976,1175,1356,1693]	7	hSpCas9	negative selection	9017922
85504	85527	16	-	27260156	SKES1	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.08272387240997081	[253]	[259,232,205,255]	-2	hSpCas9	negative selection	9072119
85411	85434	16	+	27260156	SKES1	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.1950875842455797	[155]	[193,225,116,181]	4	hSpCas9	negative selection	9072120
138255	138278	16	+	27260156	SKES1	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	0.4027682525395071	[77]	[108,116,92,94]	8	hSpCas9	negative selection	9074914
138231	138254	16	-	27260156	SKES1	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.3742226111734521	[1269]	[2033,1798,1337,1476]	7	hSpCas9	negative selection	9074915
110524	110547	16	-	27260156	SKES1	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.014754016280540738	[760]	[744,755,756,793]	0	hSpCas9	negative selection	9074916
92712	92735	16	-	27260156	SKES1	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.1582737035809847	[711]	[694,628,597,625]	-3	hSpCas9	negative selection	9139171
112700	112723	16	-	27260156	SKES1	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.1932549473543954	[144]	[164,113,198,173]	4	hSpCas9	negative selection	9139172
92613	92636	16	-	27260156	SKES1	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.4648784602349082	[918]	[1738,1167,1140,1077]	8	hSpCas9	negative selection	9139173
85504	85527	16	-	27260156	TOV112D	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.3023077832378771	[253]	[357,201,157,120]	-5	hSpCas9	negative selection	9193370
85411	85434	16	+	27260156	TOV112D	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.6207819200786607	[155]	[107,426,167,290]	9	hSpCas9	negative selection	9193371
138255	138278	16	+	27260156	TOV112D	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	1.1658137819931058	[77]	[80,126,225,244]	9	hSpCas9	negative selection	9196165
138231	138254	16	-	27260156	TOV112D	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.3204594233230662	[1269]	[1891,2053,1684,879]	6	hSpCas9	negative selection	9196166
110524	110547	16	-	27260156	TOV112D	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.35724530041723146	[760]	[832,1146,1134,822]	6	hSpCas9	negative selection	9196167
92712	92735	16	-	27260156	TOV112D	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	-0.036068585813472054	[711]	[741,848,661,572]	0	hSpCas9	negative selection	9260422
112700	112723	16	-	27260156	TOV112D	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.7452052886560946	[144]	[291,228,214,237]	9	hSpCas9	negative selection	9260423
92613	92636	16	-	27260156	TOV112D	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.3785343196379657	[918]	[951,1393,932,1523]	7	hSpCas9	negative selection	9260424
85504	85527	16	-	27260156	TC71	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	0.0310430206546225	[253]	[292,347,226,243]	0	hSpCas9	negative selection	9314621
85411	85434	16	+	27260156	TC71	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.24841640899455264	[155]	[236,172,156,229]	6	hSpCas9	negative selection	9314622
138255	138278	16	+	27260156	TC71	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.20996532555386782	[77]	[50,77,68,92]	-5	hSpCas9	negative selection	9317416
138231	138254	16	-	27260156	TC71	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.3169789590004546	[1269]	[1654,1681,1694,1755]	7	hSpCas9	negative selection	9317417
110524	110547	16	-	27260156	TC71	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.03756857508429223	[760]	[906,831,718,896]	1	hSpCas9	negative selection	9317418
92712	92735	16	-	27260156	TC71	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.0012837723478814622	[711]	[724,700,804,827]	0	hSpCas9	negative selection	9381673
112700	112723	16	-	27260156	TC71	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.2897369230967375	[144]	[247,128,197,182]	7	hSpCas9	negative selection	9381674
92613	92636	16	-	27260156	TC71	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.19871495337321698	[918]	[1155,1076,1055,1241]	5	hSpCas9	negative selection	9381675
85504	85527	16	-	27260156	TC32	viability	TGCAGAGCTCGCGGTCCTTGAGG	NPRL3	ENSG00000103148	-0.12806358324679645	[253]	[226,136,297,243]	-2	hSpCas9	negative selection	9435872
85411	85434	16	+	27260156	TC32	viability	TTGCGTCTTGCTGCGAGCACTGG	NPRL3	ENSG00000103148	0.3692857921942643	[155]	[203,112,243,223]	6	hSpCas9	negative selection	9435873
138255	138278	16	+	27260156	TC32	viability	TGTTGTCCCGCATCCCGCCGTGG	NPRL3	ENSG00000103148	-0.11426675411670528	[77]	[70,35,84,90]	-2	hSpCas9	negative selection	9438667
138231	138254	16	-	27260156	TC32	viability	CAGCCCCATCAGCGTGATTCTGG	NPRL3	ENSG00000103148	0.9714068607759758	[1269]	[2216,1529,3085,2874]	9	hSpCas9	negative selection	9438668
110524	110547	16	-	27260156	TC32	viability	ACCTCAAGGAAGCTTATGACAGG	NPRL3	ENSG00000103148	0.4333886197173077	[760]	[877,757,1254,1058]	7	hSpCas9	negative selection	9438669
92712	92735	16	-	27260156	TC32	viability	TGCCTGCAGGTACTCCCCGCTGG	NPRL3	ENSG00000103148	0.3261133835248329	[711]	[692,505,1219,1116]	6	hSpCas9	negative selection	9502924
112700	112723	16	-	27260156	TC32	viability	CGCCACCGTGCTGCAGCACGAGG	NPRL3	ENSG00000103148	0.2701282080570928	[144]	[180,94,196,206]	5	hSpCas9	negative selection	9502925
92613	92636	16	-	27260156	TC32	viability	GTCAGAATTTAGGAATCCCCTGG	NPRL3	ENSG00000103148	0.5792814246854713	[918]	[1112,1036,1784,1356]	8	hSpCas9	negative selection	9502926
98210	98233	16	+	27869803	HPAFII	viability after 27 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	-0.1559160384419367	[387]	[43,298,NaN]	-1	hSpCas9	negative selection	9555707
100487	100510	16	+	27869803	HPAFII	viability after 27 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	0.9571703412849182	[135]	[200,86,NaN]	7	hSpCas9	negative selection	9555712
110553	110576	16	-	27869803	HPAFII	viability after 27 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	0.9361087257570886	[183]	[225,150,NaN]	7	hSpCas9	negative selection	9555782
112695	112718	16	+	27869803	HPAFII	viability after 27 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.7491874153527366	[432]	[314,438,NaN]	6	hSpCas9	negative selection	9555788
130555	130578	16	-	27869803	HPAFII	viability after 27 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.3620962297793643	[417]	[174,371,NaN]	3	hSpCas9	negative selection	9555815
138144	138167	16	+	27869803	HPAFII	viability after 27 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	0.8373826454041253	[68]	[42,82,NaN]	6	hSpCas9	negative selection	9555865
98210	98233	16	+	27869803	HPAFII	viability after 15 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	-0.39613519308365497	[387]	[187,396,NaN]	-4	hSpCas9	negative selection	9638156
100487	100510	16	+	27869803	HPAFII	viability after 15 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	0.5698439189297266	[135]	[314,155,NaN]	6	hSpCas9	negative selection	9638161
110553	110576	16	-	27869803	HPAFII	viability after 15 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	0.158138610866989	[183]	[314,161,NaN]	1	hSpCas9	negative selection	9638231
112695	112718	16	+	27869803	HPAFII	viability after 15 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.2837706423880958	[432]	[539,582,NaN]	3	hSpCas9	negative selection	9638237
130555	130578	16	-	27869803	HPAFII	viability after 15 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.05175835197207357	[417]	[604,378,NaN]	0	hSpCas9	negative selection	9638264
138144	138167	16	+	27869803	HPAFII	viability after 15 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	1.4334587863759334	[68]	[285,146,NaN]	9	hSpCas9	negative selection	9638314
98210	98233	16	+	27869803	ASPC1	viability after 36 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	0.43354270869761685	[786]	[565,247,327]	4	hSpCas9	negative selection	9720605
100487	100510	16	+	27869803	ASPC1	viability after 36 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-1.761525376403127	[200]	[37,5,19]	-9	hSpCas9	negative selection	9720610
110553	110576	16	-	27869803	ASPC1	viability after 36 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	0.3403061320629801	[326]	[67,293,77]	3	hSpCas9	negative selection	9720680
112695	112718	16	+	27869803	ASPC1	viability after 36 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	-0.3019175448329221	[1221]	[337,471,247]	-3	hSpCas9	negative selection	9720686
130555	130578	16	-	27869803	ASPC1	viability after 36 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.6641362660225091	[1028]	[764,733,294]	6	hSpCas9	negative selection	9720713
138144	138167	16	+	27869803	ASPC1	viability after 36 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	-0.18492345334728122	[318]	[111,155,40]	-2	hSpCas9	negative selection	9720763
98210	98233	16	+	27869803	PATU8988S	viability after 35 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	-0.2845082418694619	[780]	[148,367,NaN]	-3	hSpCas9	negative selection	9803054
100487	100510	16	+	27869803	PATU8988S	viability after 35 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-0.12443012564902445	[344]	[112,141,NaN]	-1	hSpCas9	negative selection	9803059
110553	110576	16	-	27869803	PATU8988S	viability after 35 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	-0.7434481600081505	[431]	[70,136,NaN]	-6	hSpCas9	negative selection	9803129
112695	112718	16	+	27869803	PATU8988S	viability after 35 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	1.3727610974287567	[1110]	[1270,1045,NaN]	9	hSpCas9	negative selection	9803135
130555	130578	16	-	27869803	PATU8988S	viability after 35 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.26743662040679417	[929]	[381,519,NaN]	3	hSpCas9	negative selection	9803162
138144	138167	16	+	27869803	PATU8988S	viability after 35 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	-0.14407537930189374	[291]	[73,138,NaN]	-1	hSpCas9	negative selection	9803212
98210	98233	16	+	27869803	PATU8988S	viability after 31 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	0.1311178338497887	[780]	[183,540,NaN]	1	hSpCas9	negative selection	9885503
100487	100510	16	+	27869803	PATU8988S	viability after 31 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	-0.30700768587599836	[344]	[97,127,NaN]	-3	hSpCas9	negative selection	9885508
110553	110576	16	-	27869803	PATU8988S	viability after 31 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	-0.0287221653621193	[431]	[79,281,NaN]	0	hSpCas9	negative selection	9885578
112695	112718	16	+	27869803	PATU8988S	viability after 31 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	1.4334301386766262	[1110]	[910,1559,NaN]	9	hSpCas9	negative selection	9885584
130555	130578	16	-	27869803	PATU8988S	viability after 31 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.18785095681782882	[929]	[428,413,NaN]	2	hSpCas9	negative selection	9885611
138144	138167	16	+	27869803	PATU8988S	viability after 31 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	0.1189248542392396	[291]	[114,140,NaN]	1	hSpCas9	negative selection	9885661
98210	98233	16	+	27869803	HPAFII	viability after 35 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	0.289470166481385	[387]	[18,488,NaN]	1	hSpCas9	negative selection	9967952
100487	100510	16	+	27869803	HPAFII	viability after 35 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	0.06470910315871325	[135]	[87,53,NaN]	0	hSpCas9	negative selection	9967957
110553	110576	16	-	27869803	HPAFII	viability after 35 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	0.6336298504062593	[183]	[120,170,NaN]	4	hSpCas9	negative selection	9968027
112695	112718	16	+	27869803	HPAFII	viability after 35 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.5163233845254035	[432]	[194,446,NaN]	3	hSpCas9	negative selection	9968033
130555	130578	16	-	27869803	HPAFII	viability after 35 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.5487184633653536	[417]	[214,415,NaN]	3	hSpCas9	negative selection	9968060
138144	138167	16	+	27869803	HPAFII	viability after 35 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	1.1877017404569727	[68]	[40,122,NaN]	7	hSpCas9	negative selection	9968110
98210	98233	16	+	27869803	HPAFII	viability after 31 days	TGATCACCCGCACTAGGGCAGGG	NPRL3	ENSG00000103148	0.05618850543264997	[387]	[11,459,NaN]	0	hSpCas9	negative selection	10050401
100487	100510	16	+	27869803	HPAFII	viability after 31 days	GAACTACGCCCGACGTGCACAGG	NPRL3	ENSG00000103148	0.9723893640271909	[135]	[188,106,NaN]	7	hSpCas9	negative selection	10050406
110553	110576	16	-	27869803	HPAFII	viability after 31 days	CATCCTGCCCAAGTGCAAGCTGG	NPRL3	ENSG00000103148	0.38050523428917743	[183]	[143,123,NaN]	2	hSpCas9	negative selection	10050476
112695	112718	16	+	27869803	HPAFII	viability after 31 days	GCGCTCCTCGTGCTGCAGCACGG	NPRL3	ENSG00000103148	0.2820228064757061	[432]	[238,356,NaN]	2	hSpCas9	negative selection	10050482
130555	130578	16	-	27869803	HPAFII	viability after 31 days	AGATACGCTGCCAGCAACACGGG	NPRL3	ENSG00000103148	0.4554560563101163	[417]	[224,426,NaN]	3	hSpCas9	negative selection	10050509
138144	138167	16	+	27869803	HPAFII	viability after 31 days	ACTTACTTGTCTGGGACGCCGGG	NPRL3	ENSG00000103148	0.7066993961868293	[68]	[22,106,NaN]	5	hSpCas9	negative selection	10050559
98162	98185	16	-	28162770	P31FUJ	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	-0.2750854502593105	[1557]	[1512]	-3	hSpCas9	negative selection	10202052
98211	98234	16	+	28162770	P31FUJ	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	0.1438005719488138	[2966]	[3851]	1	hSpCas9	negative selection	10202053
112611	112634	16	+	28162770	P31FUJ	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	0.36531166395808246	[363]	[550]	4	hSpCas9	negative selection	10202054
92651	92674	16	+	28162770	P31FUJ	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	-0.2211392868887989	[615]	[620]	-2	hSpCas9	negative selection	10202055
89881	89904	16	-	28162770	P31FUJ	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	0.002102828235618137	[491]	[578]	0	hSpCas9	negative selection	10202056
89710	89733	16	+	28162770	P31FUJ	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	0.2353850013832295	[1358]	[1879]	2	hSpCas9	negative selection	10202057
88844	88867	16	+	28162770	P31FUJ	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	0.33985340085516436	[1294]	[1925]	4	hSpCas9	negative selection	10202058
88823	88846	16	+	28162770	P31FUJ	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	0.16815233246772499	[1363]	[1800]	1	hSpCas9	negative selection	10202059
88799	88822	16	-	28162770	P31FUJ	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	0.02532107613509549	[1127]	[1348]	0	hSpCas9	negative selection	10202060
98279	98302	16	+	28162770	P31FUJ	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	-0.03769560899906965	[1829]	[2094]	0	hSpCas9	negative selection	10202061
98162	98185	16	-	28162770	TF1	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	NaN	[NaN]	[141]	1	hSpCas9	negative selection	10371418
98211	98234	16	+	28162770	TF1	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	NaN	[NaN]	[530]	1	hSpCas9	negative selection	10371419
112611	112634	16	+	28162770	TF1	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10371420
92651	92674	16	+	28162770	TF1	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	NaN	[NaN]	[98]	1	hSpCas9	negative selection	10371421
89881	89904	16	-	28162770	TF1	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10371422
89710	89733	16	+	28162770	TF1	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	NaN	[NaN]	[163]	1	hSpCas9	negative selection	10371423
88844	88867	16	+	28162770	TF1	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	NaN	[NaN]	[217]	1	hSpCas9	negative selection	10371424
88823	88846	16	+	28162770	TF1	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10371425
88799	88822	16	-	28162770	TF1	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10371426
98279	98302	16	+	28162770	TF1	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	NaN	[NaN]	[97]	1	hSpCas9	negative selection	10371427
98162	98185	16	-	28162770	SKM1	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	0.6544363459209819	[91]	[255]	6	hSpCas9	negative selection	10540784
98211	98234	16	+	28162770	SKM1	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	0.5297616264061198	[200]	[512]	5	hSpCas9	negative selection	10540785
112611	112634	16	+	28162770	SKM1	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	0.5886306221368373	[40]	[108]	5	hSpCas9	negative selection	10540786
92651	92674	16	+	28162770	SKM1	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	-0.2549611052981117	[53]	[79]	-2	hSpCas9	negative selection	10540787
89881	89904	16	-	28162770	SKM1	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	-1.1630386158570725	[37]	[29]	-7	hSpCas9	negative selection	10540788
89710	89733	16	+	28162770	SKM1	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	-0.05261462616342194	[87]	[149]	0	hSpCas9	negative selection	10540789
88844	88867	16	+	28162770	SKM1	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	-0.8220016980220054	[91]	[91]	-6	hSpCas9	negative selection	10540790
88823	88846	16	+	28162770	SKM1	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	0.04524309312622288	[90]	[165]	0	hSpCas9	negative selection	10540791
88799	88822	16	-	28162770	SKM1	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	-0.436110544402678	[74]	[97]	-4	hSpCas9	negative selection	10540792
98279	98302	16	+	28162770	SKM1	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	0.27365054104168074	[123]	[264]	2	hSpCas9	negative selection	10540793
98162	98185	16	-	28162770	SKM1	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	0.6544363459209819	[91]	[255]	6	hSpCas9	negative selection	10710150
98211	98234	16	+	28162770	SKM1	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	0.5297616264061198	[200]	[512]	5	hSpCas9	negative selection	10710151
112611	112634	16	+	28162770	SKM1	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	0.5886306221368373	[40]	[108]	5	hSpCas9	negative selection	10710152
92651	92674	16	+	28162770	SKM1	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	-0.2549611052981117	[53]	[79]	-2	hSpCas9	negative selection	10710153
89881	89904	16	-	28162770	SKM1	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	-1.1630386158570725	[37]	[29]	-7	hSpCas9	negative selection	10710154
89710	89733	16	+	28162770	SKM1	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	-0.05261462616342194	[87]	[149]	0	hSpCas9	negative selection	10710155
88844	88867	16	+	28162770	SKM1	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	-0.8220016980220054	[91]	[91]	-6	hSpCas9	negative selection	10710156
88823	88846	16	+	28162770	SKM1	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	0.04524309312622288	[90]	[165]	0	hSpCas9	negative selection	10710157
88799	88822	16	-	28162770	SKM1	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	-0.436110544402678	[74]	[97]	-4	hSpCas9	negative selection	10710158
98279	98302	16	+	28162770	SKM1	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	0.27365054104168074	[123]	[264]	2	hSpCas9	negative selection	10710159
98162	98185	16	-	28162770	PL21	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	-1.9741113123557823	[333]	[36]	-8	hSpCas9	negative selection	10879516
98211	98234	16	+	28162770	PL21	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	-0.4213487622569503	[719]	[233]	-3	hSpCas9	negative selection	10879517
112611	112634	16	+	28162770	PL21	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	0.3616030371834363	[151]	[84]	3	hSpCas9	negative selection	10879518
92651	92674	16	+	28162770	PL21	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	-3.5393999233407123	[186]	[6]	-9	hSpCas9	negative selection	10879519
89881	89904	16	-	28162770	PL21	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	-1.5578875952047155	[114]	[16]	-7	hSpCas9	negative selection	10879520
89710	89733	16	+	28162770	PL21	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	0.16348114391047197	[278]	[135]	1	hSpCas9	negative selection	10879521
88844	88867	16	+	28162770	PL21	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	-0.22031138097588798	[355]	[132]	-1	hSpCas9	negative selection	10879522
88823	88846	16	+	28162770	PL21	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	-0.40374374812906466	[306]	[100]	-3	hSpCas9	negative selection	10879523
88799	88822	16	-	28162770	PL21	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	-2.389268791263028	[324]	[26]	-8	hSpCas9	negative selection	10879524
98279	98302	16	+	28162770	PL21	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	-1.8275757637225027	[472]	[57]	-8	hSpCas9	negative selection	10879525
98162	98185	16	-	28162770	P31FUJ	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	-0.2750854502593105	[1557]	[1512]	-3	hSpCas9	negative selection	11048882
98211	98234	16	+	28162770	P31FUJ	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	0.1438005719488138	[2966]	[3851]	1	hSpCas9	negative selection	11048883
112611	112634	16	+	28162770	P31FUJ	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	0.36531166395808246	[363]	[550]	4	hSpCas9	negative selection	11048884
92651	92674	16	+	28162770	P31FUJ	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	-0.2211392868887989	[615]	[620]	-2	hSpCas9	negative selection	11048885
89881	89904	16	-	28162770	P31FUJ	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	0.002102828235618137	[491]	[578]	0	hSpCas9	negative selection	11048886
89710	89733	16	+	28162770	P31FUJ	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	0.2353850013832295	[1358]	[1879]	2	hSpCas9	negative selection	11048887
88844	88867	16	+	28162770	P31FUJ	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	0.33985340085516436	[1294]	[1925]	4	hSpCas9	negative selection	11048888
88823	88846	16	+	28162770	P31FUJ	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	0.16815233246772499	[1363]	[1800]	1	hSpCas9	negative selection	11048889
88799	88822	16	-	28162770	P31FUJ	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	0.02532107613509549	[1127]	[1348]	0	hSpCas9	negative selection	11048890
98279	98302	16	+	28162770	P31FUJ	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	-0.03769560899906965	[1829]	[2094]	0	hSpCas9	negative selection	11048891
98162	98185	16	-	28162770	OCIAML5	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	-1.9848217797157686	[181]	[82]	-8	hSpCas9	negative selection	11218248
98211	98234	16	+	28162770	OCIAML5	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	-1.1793084656478272	[339]	[270]	-6	hSpCas9	negative selection	11218249
112611	112634	16	+	28162770	OCIAML5	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	-2.5525062890050894	[51]	[15]	-8	hSpCas9	negative selection	11218250
92651	92674	16	+	28162770	OCIAML5	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	-7.734709620225838	[117]	[0]	-9	hSpCas9	negative selection	11218251
89881	89904	16	-	28162770	OCIAML5	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	-4.507418399476551	[62]	[4]	-9	hSpCas9	negative selection	11218252
89710	89733	16	+	28162770	OCIAML5	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	-2.2611792361857352	[161]	[60]	-8	hSpCas9	negative selection	11218253
88844	88867	16	+	28162770	OCIAML5	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	-0.5966338877635415	[221]	[264]	-4	hSpCas9	negative selection	11218254
88823	88846	16	+	28162770	OCIAML5	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	-1.6728420086839226	[188]	[106]	-7	hSpCas9	negative selection	11218255
88799	88822	16	-	28162770	OCIAML5	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	-0.46677641497920513	[97]	[127]	-3	hSpCas9	negative selection	11218256
98279	98302	16	+	28162770	OCIAML5	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	-1.4050002173925153	[244]	[166]	-7	hSpCas9	negative selection	11218257
98162	98185	16	-	28162770	EOL1	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	-3.0221227260233388	[477]	[30]	-9	hSpCas9	negative selection	11387614
98211	98234	16	+	28162770	EOL1	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	-0.44016064216101203	[1060]	[411]	-3	hSpCas9	negative selection	11387615
112611	112634	16	+	28162770	EOL1	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	-1.4723423809980498	[157]	[29]	-7	hSpCas9	negative selection	11387616
92651	92674	16	+	28162770	EOL1	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	-1.4277539723603465	[239]	[46]	-7	hSpCas9	negative selection	11387617
89881	89904	16	-	28162770	EOL1	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	-1.5627180552634883	[156]	[27]	-7	hSpCas9	negative selection	11387618
89710	89733	16	+	28162770	EOL1	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	1.1318089242858196	[355]	[410]	8	hSpCas9	negative selection	11387619
88844	88867	16	+	28162770	EOL1	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	0.37614817655945465	[486]	[332]	3	hSpCas9	negative selection	11387620
88823	88846	16	+	28162770	EOL1	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	-0.3474754174905141	[482]	[199]	-3	hSpCas9	negative selection	11387621
88799	88822	16	-	28162770	EOL1	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	0.3301865728471287	[461]	[305]	3	hSpCas9	negative selection	11387622
98279	98302	16	+	28162770	EOL1	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	-2.1128127559333927	[664]	[80]	-8	hSpCas9	negative selection	11387623
98162	98185	16	-	28162770	MOLM13	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	-2.764192095960303	[497]	[52]	-8	hSpCas9	negative selection	11556980
98211	98234	16	+	28162770	MOLM13	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	-1.2666616596883273	[994]	[298]	-6	hSpCas9	negative selection	11556981
112611	112634	16	+	28162770	MOLM13	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	-0.511352058288624	[206]	[104]	-3	hSpCas9	negative selection	11556982
92651	92674	16	+	28162770	MOLM13	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	-1.9566084469833311	[203]	[37]	-7	hSpCas9	negative selection	11556983
89881	89904	16	-	28162770	MOLM13	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	-1.4390012140639397	[119]	[31]	-6	hSpCas9	negative selection	11556984
89710	89733	16	+	28162770	MOLM13	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	-0.47446295945560535	[416]	[216]	-3	hSpCas9	negative selection	11556985
88844	88867	16	+	28162770	MOLM13	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	0.1275827573423619	[394]	[311]	0	hSpCas9	negative selection	11556986
88823	88846	16	+	28162770	MOLM13	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	-0.9923368915005204	[453]	[164]	-5	hSpCas9	negative selection	11556987
88799	88822	16	-	28162770	MOLM13	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	0.20291717146929245	[446]	[371]	1	hSpCas9	negative selection	11556988
98279	98302	16	+	28162770	MOLM13	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	-0.772002944476772	[469]	[198]	-4	hSpCas9	negative selection	11556989
98162	98185	16	-	28162770	HEL	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	-0.5967271026950324	[339]	[143]	-4	hSpCas9	negative selection	11726346
98211	98234	16	+	28162770	HEL	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	0.08779447618336533	[760]	[517]	0	hSpCas9	negative selection	11726347
112611	112634	16	+	28162770	HEL	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	0.39542877845957963	[145]	[122]	3	hSpCas9	negative selection	11726348
92651	92674	16	+	28162770	HEL	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	0.14483306554842396	[208]	[147]	1	hSpCas9	negative selection	11726349
89881	89904	16	-	28162770	HEL	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	-0.7688920658352373	[140]	[52]	-5	hSpCas9	negative selection	11726350
89710	89733	16	+	28162770	HEL	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	0.5368937443704331	[310]	[288]	4	hSpCas9	negative selection	11726351
88844	88867	16	+	28162770	HEL	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	-0.6125182232417177	[369]	[154]	-4	hSpCas9	negative selection	11726352
88823	88846	16	+	28162770	HEL	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	-0.029966563362465337	[321]	[201]	0	hSpCas9	negative selection	11726353
88799	88822	16	-	28162770	HEL	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	-0.42896263335383167	[329]	[156]	-3	hSpCas9	negative selection	11726354
98279	98302	16	+	28162770	HEL	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	0.31661074858370897	[429]	[342]	2	hSpCas9	negative selection	11726355
98162	98185	16	-	28162770	MV411	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	-0.8263826825088962	[420]	[199]	-5	hSpCas9	negative selection	11895712
98211	98234	16	+	28162770	MV411	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	0.04668192396457149	[738]	[642]	0	hSpCas9	negative selection	11895713
112611	112634	16	+	28162770	MV411	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	-0.15552711619549342	[118]	[89]	-1	hSpCas9	negative selection	11895714
92651	92674	16	+	28162770	MV411	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	0.11673385913818174	[126]	[115]	1	hSpCas9	negative selection	11895715
89881	89904	16	-	28162770	MV411	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	-2.4209409581260184	[88]	[13]	-8	hSpCas9	negative selection	11895716
89710	89733	16	+	28162770	MV411	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	0.04140857565521461	[262]	[227]	0	hSpCas9	negative selection	11895717
88844	88867	16	+	28162770	MV411	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	-0.6055600368305412	[288]	[159]	-4	hSpCas9	negative selection	11895718
88823	88846	16	+	28162770	MV411	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	-0.9467349969062145	[404]	[176]	-6	hSpCas9	negative selection	11895719
88799	88822	16	-	28162770	MV411	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	0.16170767675689135	[311]	[293]	1	hSpCas9	negative selection	11895720
98279	98302	16	+	28162770	MV411	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	0.09046820444437587	[387]	[347]	0	hSpCas9	negative selection	11895721
98162	98185	16	-	28162770	MONOMAC1	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	-0.5040146004809445	[239]	[193]	-4	hSpCas9	negative selection	12065078
98211	98234	16	+	28162770	MONOMAC1	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	0.1655332323251546	[454]	[584]	1	hSpCas9	negative selection	12065079
112611	112634	16	+	28162770	MONOMAC1	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	0.6762060106545077	[106]	[195]	6	hSpCas9	negative selection	12065080
92651	92674	16	+	28162770	MONOMAC1	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	0.22888896836202627	[98]	[132]	2	hSpCas9	negative selection	12065081
89881	89904	16	-	28162770	MONOMAC1	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	-0.26742617495095156	[83]	[79]	-2	hSpCas9	negative selection	12065082
89710	89733	16	+	28162770	MONOMAC1	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	0.20852789959900786	[190]	[252]	2	hSpCas9	negative selection	12065083
88844	88867	16	+	28162770	MONOMAC1	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	0.3516621096748308	[187]	[274]	3	hSpCas9	negative selection	12065084
88823	88846	16	+	28162770	MONOMAC1	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	0.38315640951373064	[201]	[301]	4	hSpCas9	negative selection	12065085
88799	88822	16	-	28162770	MONOMAC1	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	-0.49609047569432935	[218]	[177]	-4	hSpCas9	negative selection	12065086
98279	98302	16	+	28162770	MONOMAC1	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	-0.07365443155427176	[335]	[365]	0	hSpCas9	negative selection	12065087
98162	98185	16	-	28162770	OCIAML2	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	-2.343250518765934	[64]	[70]	-8	hSpCas9	negative selection	12234444
98211	98234	16	+	28162770	OCIAML2	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	-0.787435487516936	[122]	[394]	-5	hSpCas9	negative selection	12234445
112611	112634	16	+	28162770	OCIAML2	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	-1.1751739417159899	[32]	[80]	-6	hSpCas9	negative selection	12234446
92651	92674	16	+	28162770	OCIAML2	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	-3.470629825242161	[33]	[16]	-9	hSpCas9	negative selection	12234447
89881	89904	16	-	28162770	OCIAML2	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	-0.8679653227875461	[26]	[81]	-6	hSpCas9	negative selection	12234448
89710	89733	16	+	28162770	OCIAML2	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	-0.5053952434028379	[62]	[245]	-4	hSpCas9	negative selection	12234449
88844	88867	16	+	28162770	OCIAML2	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	0.21787027958740568	[55]	[360]	2	hSpCas9	negative selection	12234450
88823	88846	16	+	28162770	OCIAML2	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	-1.0625450866050843	[77]	[206]	-6	hSpCas9	negative selection	12234451
88799	88822	16	-	28162770	OCIAML2	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	-0.5585025812674956	[54]	[206]	-4	hSpCas9	negative selection	12234452
98279	98302	16	+	28162770	OCIAML2	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	-1.4346505281365947	[98]	[202]	-7	hSpCas9	negative selection	12234453
98162	98185	16	-	28162770	OCIAML3	viability	GCAGCAGCTAGCCCAAGATGCGG	NPRL3	ENSG00000103148	2.9442010916972507	[97]	[2276]	9	hSpCas9	negative selection	12403810
98211	98234	16	+	28162770	OCIAML3	viability	GATCACCCGCACTAGGGCAGGGG	NPRL3	ENSG00000103148	1.4969868918964295	[143]	[1226]	9	hSpCas9	negative selection	12403811
112611	112634	16	+	28162770	OCIAML3	viability	GCTGCACTCACCATCAGCCATGG	NPRL3	ENSG00000103148	1.3841879893574882	[24]	[196]	9	hSpCas9	negative selection	12403812
92651	92674	16	+	28162770	OCIAML3	viability	GAGAACTTGGCAAGAACGGACGG	NPRL3	ENSG00000103148	2.7654979123796757	[35]	[738]	9	hSpCas9	negative selection	12403813
89881	89904	16	-	28162770	OCIAML3	viability	GACCCAGCTCATCCAGATGGTGG	NPRL3	ENSG00000103148	1.3097770444165338	[30]	[231]	9	hSpCas9	negative selection	12403814
89710	89733	16	+	28162770	OCIAML3	viability	TACTTGGGGAGCCAAAGCTGAGG	NPRL3	ENSG00000103148	0.7440852739942061	[70]	[358]	6	hSpCas9	negative selection	12403815
88844	88867	16	+	28162770	OCIAML3	viability	GGAGTTGTCCATGCTGGGGCTGG	NPRL3	ENSG00000103148	0.9971070873785883	[77]	[469]	8	hSpCas9	negative selection	12403816
88823	88846	16	+	28162770	OCIAML3	viability	GCTGGGAAGTAGCTCTGCGCTGG	NPRL3	ENSG00000103148	1.9524807125823573	[75]	[887]	9	hSpCas9	negative selection	12403817
88799	88822	16	-	28162770	OCIAML3	viability	GGGACTCGCCACTGAACCAGAGG	NPRL3	ENSG00000103148	0.6452434317539717	[78]	[372]	6	hSpCas9	negative selection	12403818
98279	98302	16	+	28162770	OCIAML3	viability	GCAGCAGCAGGGCATGGTAGGGG	NPRL3	ENSG00000103148	1.5421290476618659	[119]	[1054]	9	hSpCas9	negative selection	12403819