Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 4893
• Symbol: NRAS
• Description: NRAS proto-oncogene, GTPase

DataSource: http://genomecrispr.dkfz.de/#!/results/NRAS

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
114716139	114716162	1	-	26472758	Jiyoye	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	0.8967598341497712	[98]	[138]	6	hSpCas9	negative selection	111264
114713911	114713934	1	-	26472758	Jiyoye	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	2.0834781937654556	[50]	[162]	8	hSpCas9	negative selection	111265
114716038	114716061	1	+	26472758	Jiyoye	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	0.46023662525728715	[346]	[359]	3	hSpCas9	negative selection	111266
114713786	114713809	1	+	26472758	Jiyoye	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	0.6177423674455318	[139]	[161]	4	hSpCas9	negative selection	111267
114716126	114716149	1	-	26472758	Jiyoye	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	4.655102894949458	[0]	[18]	9	hSpCas9	negative selection	111268
114713860	114713883	1	-	26472758	Jiyoye	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	-0.14216320948456163	[179]	[122]	-1	hSpCas9	negative selection	111269
114713871	114713894	1	-	26472758	Jiyoye	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.4672963739434445	[46]	[48]	3	hSpCas9	negative selection	111270
114709619	114709642	1	-	26472758	Jiyoye	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-2.5314240738299834	[68]	[8]	-9	hSpCas9	negative selection	111271
114709596	114709619	1	+	26472758	Jiyoye	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-0.1398576635829606	[243]	[166]	-1	hSpCas9	negative selection	111272
114716049	114716072	1	-	26472758	Jiyoye	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	-0.48914597239245794	[254]	[136]	-4	hSpCas9	negative selection	111273
114716139	114716162	1	-	26472758	KBM7	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	0.36130230344355196	[878,485]	[456,352]	4	hSpCas9	negative selection	302382
114713911	114713934	1	-	26472758	KBM7	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	-0.0032368195081111314	[603,402]	[212,249]	0	hSpCas9	negative selection	302383
114716038	114716061	1	+	26472758	KBM7	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	-0.1724514125239638	[1761,1605]	[840,578]	-2	hSpCas9	negative selection	302384
114713786	114713809	1	+	26472758	KBM7	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	0.029651535118323302	[876,689]	[367,377]	0	hSpCas9	negative selection	302385
114716126	114716149	1	-	26472758	KBM7	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	1.0704126304505426	[136,97]	[102,124]	9	hSpCas9	negative selection	302386
114713860	114713883	1	-	26472758	KBM7	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	-0.48687606002080985	[823,643]	[208,275]	-4	hSpCas9	negative selection	302387
114713871	114713894	1	-	26472758	KBM7	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.06198692460708555	[462,362]	[140,254]	0	hSpCas9	negative selection	302388
114709619	114709642	1	-	26472758	KBM7	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	0.21800293830924677	[102,125]	[33,89]	2	hSpCas9	negative selection	302389
114709596	114709619	1	+	26472758	KBM7	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.17412714043353283	[621,717]	[382,338]	1	hSpCas9	negative selection	302390
114716049	114716072	1	-	26472758	KBM7	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	-0.6164810522704325	[723,599]	[247,160]	-5	hSpCas9	negative selection	302391
114716139	114716162	1	-	26472758	Raji	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	-0.021349778748603387	[327]	[74]	0	hSpCas9	negative selection	493500
114713911	114713934	1	-	26472758	Raji	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	-1.0201061997483163	[200]	[22]	-6	hSpCas9	negative selection	493501
114716038	114716061	1	+	26472758	Raji	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	-0.19201799049715484	[698]	[141]	-2	hSpCas9	negative selection	493502
114713786	114713809	1	+	26472758	Raji	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	-0.665205968523328	[286]	[41]	-5	hSpCas9	negative selection	493503
114716126	114716149	1	-	26472758	Raji	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	0.7288719121198697	[64]	[24]	6	hSpCas9	negative selection	493504
114713860	114713883	1	-	26472758	Raji	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	0.2870429717215147	[278]	[78]	2	hSpCas9	negative selection	493505
114713871	114713894	1	-	26472758	Raji	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.2145445595137629	[274]	[54]	-2	hSpCas9	negative selection	493506
114709619	114709642	1	-	26472758	Raji	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.14895621788618607	[42]	[8]	-1	hSpCas9	negative selection	493507
114709596	114709619	1	+	26472758	Raji	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-0.35053977675842063	[477]	[86]	-3	hSpCas9	negative selection	493508
114716049	114716072	1	-	26472758	Raji	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	-0.567216177832233	[414]	[64]	-4	hSpCas9	negative selection	493509
114716139	114716162	1	-	26472758	K562	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	-0.21305403793279348	[551]	[401]	-1	hSpCas9	negative selection	684618
114713911	114713934	1	-	26472758	K562	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	-1.6300503902496941	[450]	[122]	-7	hSpCas9	negative selection	684619
114716038	114716061	1	+	26472758	K562	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	-0.8436244647888258	[1553]	[730]	-5	hSpCas9	negative selection	684620
114713786	114713809	1	+	26472758	K562	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	0.4721861409779621	[420]	[492]	4	hSpCas9	negative selection	684621
114716126	114716149	1	-	26472758	K562	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	1.0252202306827343	[187]	[322]	8	hSpCas9	negative selection	684622
114713860	114713883	1	-	26472758	K562	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	-0.1585769453411353	[516]	[390]	-1	hSpCas9	negative selection	684623
114713871	114713894	1	-	26472758	K562	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.21709320141189764	[346]	[251]	-1	hSpCas9	negative selection	684624
114709619	114709642	1	-	26472758	K562	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-1.308122295362332	[87]	[29]	-6	hSpCas9	negative selection	684625
114709596	114709619	1	+	26472758	K562	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.08880520224957117	[488]	[438]	0	hSpCas9	negative selection	684626
114716049	114716072	1	-	26472758	K562	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	-0.8285831032764599	[607]	[288]	-5	hSpCas9	negative selection	684627
114708530	114708553	1	+	26627737	DLD1	viability	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.27184493393754483	[2986]	[1245,1308,873]	3	hSpCas9	negative selection	765124
114708530	114708553	1	-	26627737	DLD1	viability	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.8282957181887334	[1299]	[989,660,538]	7	hSpCas9	negative selection	765125
114708530	114708553	1	+	26627737	GBM cells	viability after 5 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.051337211573115216	[1372]	[811,713]	0	hSpCas9	negative selection	847439
114708530	114708553	1	-	26627737	GBM cells	viability after 5 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.1085757375221359	[747]	[409,454]	1	hSpCas9	negative selection	847440
114708530	114708553	1	+	26627737	GBM cells	viability after 13 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	-0.11312997817989245	[1372]	[717,664]	-1	hSpCas9	negative selection	929754
114708530	114708553	1	-	26627737	GBM cells	viability after 13 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.4409631451395364	[747]	[647,471]	5	hSpCas9	negative selection	929755
114708530	114708553	1	+	26627737	GBM cells	viability after 21 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	-0.04345746014206364	[1372]	[763,686]	0	hSpCas9	negative selection	1012069
114708530	114708553	1	-	26627737	GBM cells	viability after 21 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.7397564595516362	[747]	[687,669]	7	hSpCas9	negative selection	1012070
114708530	114708553	1	+	26627737	RPE1	viability after 9 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.8289667416081778	[2347]	[997,1702]	5	hSpCas9	negative selection	1094384
114708530	114708553	1	-	26627737	RPE1	viability after 9 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.7219544922974239	[2952]	[1399,1685]	5	hSpCas9	negative selection	1094385
114708530	114708553	1	+	26627737	RPE1	viability after 12 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.9464493068039745	[2347]	[1187,1244]	6	hSpCas9	negative selection	1176699
114708530	114708553	1	-	26627737	RPE1	viability after 12 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.5153870441049109	[2952]	[1066,1204]	3	hSpCas9	negative selection	1176700
114708530	114708553	1	+	26627737	RPE1	viability after 15 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	1.4053855120474772	[2347]	[1540,1969]	7	hSpCas9	negative selection	1259014
114708530	114708553	1	-	26627737	RPE1	viability after 15 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.9284546830217084	[2952]	[1485,1689]	5	hSpCas9	negative selection	1259015
114708530	114708553	1	+	26627737	RPE1	viability after 18 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	1.139471119571514	[2347]	[1364,1428]	6	hSpCas9	negative selection	1341329
114708530	114708553	1	-	26627737	RPE1	viability after 18 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.7732035666836357	[2952]	[1011,1735]	5	hSpCas9	negative selection	1341330
114708530	114708553	1	+	26627737	HeLa	viability after 8 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	-0.3240127951547538	[2186]	[967,577,778]	-3	hSpCas9	negative selection	1423644
114708530	114708553	1	-	26627737	HeLa	viability after 8 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.5631526380439411	[872]	[711,562,449]	5	hSpCas9	negative selection	1423645
114708530	114708553	1	+	26627737	HeLa	viability after 12 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	-0.5547383565681472	[2186]	[572,630,638]	-5	hSpCas9	negative selection	1505959
114708530	114708553	1	-	26627737	HeLa	viability after 12 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.7412380774164558	[872]	[539,691,565]	6	hSpCas9	negative selection	1505960
114708530	114708553	1	+	26627737	HeLa	viability after 15 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	-0.018496492211394155	[2186]	[922,621,1108]	0	hSpCas9	negative selection	1588274
114708530	114708553	1	-	26627737	HeLa	viability after 15 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.6963928483944812	[872]	[594,501,634]	5	hSpCas9	negative selection	1588275
114708530	114708553	1	+	26627737	HeLa	viability after 18 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.017561104554339124	[2186]	[652,526,1108]	0	hSpCas9	negative selection	1670589
114708530	114708553	1	-	26627737	HeLa	viability after 18 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.6979878263278261	[872]	[388,429,634]	5	hSpCas9	negative selection	1670590
114708530	114708553	1	+	26627737	HCT116	viability after 6 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.7720216372676032	[2271]	[743,535]	4	hSpCas9	negative selection	1752904
114708530	114708553	1	-	26627737	HCT116	viability after 6 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.11719082010129567	[2014]	[476,269]	0	hSpCas9	negative selection	1752905
114708530	114708553	1	+	26627737	HCT116	viability after 8 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	-0.09426564004755056	[1682]	[1071,768,769]	-1	hSpCas9	negative selection	1835219
114708530	114708553	1	-	26627737	HCT116	viability after 8 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.20171751571455543	[868]	[534,415,698]	2	hSpCas9	negative selection	1835220
114708530	114708553	1	+	26627737	HCT116	viability after 9 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	1.0326871815644298	[2271]	[1587,966]	7	hSpCas9	negative selection	1917534
114708530	114708553	1	-	26627737	HCT116	viability after 9 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.44944245949340966	[2014]	[975,543]	3	hSpCas9	negative selection	1917535
114708530	114708553	1	+	26627737	HCT116	viability after 12 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.36288620615228107	[1682]	[1239,962,1195]	3	hSpCas9	negative selection	1999849
114708530	114708553	1	-	26627737	HCT116	viability after 12 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.5530786623449291	[868]	[668,659,680]	5	hSpCas9	negative selection	1999850
114708530	114708553	1	+	26627737	HCT116	viability after 15 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.18375360762931336	[1682]	[1438,1046,851]	1	hSpCas9	negative selection	2082164
114708530	114708553	1	-	26627737	HCT116	viability after 15 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.12797755716486248	[868]	[556,494,584]	1	hSpCas9	negative selection	2082165
114708530	114708553	1	+	26627737	HCT116	viability after 18 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.5178808998485196	[1682]	[1081,1430,954]	4	hSpCas9	negative selection	2164479
114708530	114708553	1	-	26627737	HCT116	viability after 18 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.776450432909799	[868]	[505,617,1056]	6	hSpCas9	negative selection	2164480
114711273	114711296	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCCCTCTGTTGCCCAAG	NRAS	ENSG00000213281	2.420787887415494	[28,17]	[7,46]	7	dCas9-VP64	positive selection	2430912
114711273	114711296	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCCCTCTGTTGCCCAAG	NRAS	ENSG00000213281	0.2582242437662712	[17,52]	[13,12]	2	dCas9-VP64	positive selection	2526167
114709605	114709628	1	-	27260157	DLD1	viability	ACGAACTGGCCAAGAGTTACGGG	NRAS	ENSG00000213281	0.196320363738453	[]	[]	3	hSpCas9	negative selection	2575217
114716142	114716165	1	-	27260157	DLD1	viability	TGAAATGACTGAGTACAAACTGG	NRAS	ENSG00000213281	1.08392304509001	[]	[]	9	hSpCas9	negative selection	2575531
114713911	114713934	1	-	27260157	DLD1	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	1.50686978916051	[]	[]	9	hSpCas9	negative selection	2581507
114709685	114709708	1	-	27260157	DLD1	viability	AGACTCGGATGATGTACCTATGG	NRAS	ENSG00000213281	0.134730862279949	[]	[]	3	hSpCas9	negative selection	2581686
114708557	114708580	1	-	27260157	DLD1	viability	GATGGGACTCAGGGTTGTATGGG	NRAS	ENSG00000213281	-0.63422944556002	[]	[]	-5	hSpCas9	negative selection	2581820
114713871	114713894	1	-	27260157	DLD1	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.0550216355809558	[]	[]	3	hSpCas9	negative selection	2583429
114708567	114708590	1	-	27260157	DLD1	viability	CAGCAGTGATGATGGGACTCAGG	NRAS	ENSG00000213281	0.565393095962963	[]	[]	8	hSpCas9	negative selection	2585071
114709596	114709619	1	+	27260157	DLD1	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.523665318209032	[]	[]	8	hSpCas9	negative selection	2604684
114709607	114709630	1	+	27260157	DLD1	viability	CGTAACTCTTGGCCAGTTCGTGG	NRAS	ENSG00000213281	-0.123799966591899	[]	[]	-1	hSpCas9	negative selection	2607456
114716076	114716099	1	+	27260157	DLD1	viability	CAAAGTGGTTCTGGATTAGCTGG	NRAS	ENSG00000213281	0.449310849575423	[]	[]	7	hSpCas9	negative selection	2609863
114713820	114713843	1	+	27260157	DLD1	viability	AAATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	-0.559061166392451	[]	[]	-4	hSpCas9	negative selection	2612370
114709669	114709692	1	+	27260157	DLD1	viability	TTGTTTCCCACTAGCACCATAGG	NRAS	ENSG00000213281	0.0830735925614942	[]	[]	3	hSpCas9	negative selection	2612395
114716136	114716159	1	-	27260157	DLD1	viability	GACTGAGTACAAACTGGTGGTGG	NRAS	ENSG00000213281	0.0880129839760212	[]	[]	3	hSpCas9	negative selection	2612566
114713861	114713884	1	+	27260157	DLD1	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.690460148646663	[]	[]	8	hSpCas9	negative selection	2614019
114708543	114708566	1	-	27260157	DLD1	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.65543076051968	[]	[]	8	hSpCas9	negative selection	2614174
114716116	114716139	1	-	27260157	DLD1	viability	TGGTTGGAGCAGGTGGTGTTGGG	NRAS	ENSG00000213281	0.200380896784433	[]	[]	3	hSpCas9	negative selection	2616615
114716139	114716162	1	-	27260157	DLD1	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	1.11945172678358	[]	[]	9	hSpCas9	negative selection	2622690
114713860	114713883	1	-	27260157	DLD1	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	0.834865354131566	[]	[]	9	hSpCas9	negative selection	2642667
114713871	114713894	1	+	27260157	DLD1	viability	CCTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	-0.664250872506304	[]	[]	-5	hSpCas9	negative selection	2647611
114708530	114708553	1	+	27260157	DLD1	viability	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.275122993768639	[]	[]	4	hSpCas9	negative selection	2648720
114709605	114709628	1	-	27260157	HT1080	viability	ACGAACTGGCCAAGAGTTACGGG	NRAS	ENSG00000213281	-1.94882684072754	[]	[]	-9	hSpCas9	negative selection	2651347
114716142	114716165	1	-	27260157	HT1080	viability	TGAAATGACTGAGTACAAACTGG	NRAS	ENSG00000213281	-3.99340377520136	[]	[]	-9	hSpCas9	negative selection	2651661
114713911	114713934	1	-	27260157	HT1080	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	-0.830935078635101	[]	[]	-8	hSpCas9	negative selection	2657637
114709685	114709708	1	-	27260157	HT1080	viability	AGACTCGGATGATGTACCTATGG	NRAS	ENSG00000213281	-2.36846734800678	[]	[]	-9	hSpCas9	negative selection	2657816
114708557	114708580	1	-	27260157	HT1080	viability	GATGGGACTCAGGGTTGTATGGG	NRAS	ENSG00000213281	-3.76472337524612	[]	[]	-9	hSpCas9	negative selection	2657950
114713871	114713894	1	-	27260157	HT1080	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-4.9288171097669	[]	[]	-9	hSpCas9	negative selection	2659559
114708567	114708590	1	-	27260157	HT1080	viability	CAGCAGTGATGATGGGACTCAGG	NRAS	ENSG00000213281	-1.21581304764996	[]	[]	-8	hSpCas9	negative selection	2661201
114709596	114709619	1	+	27260157	HT1080	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-3.04116653584667	[]	[]	-9	hSpCas9	negative selection	2680814
114709607	114709630	1	+	27260157	HT1080	viability	CGTAACTCTTGGCCAGTTCGTGG	NRAS	ENSG00000213281	-0.965467639159033	[]	[]	-8	hSpCas9	negative selection	2683586
114716076	114716099	1	+	27260157	HT1080	viability	CAAAGTGGTTCTGGATTAGCTGG	NRAS	ENSG00000213281	-1.76660169113711	[]	[]	-9	hSpCas9	negative selection	2685993
114713820	114713843	1	+	27260157	HT1080	viability	AAATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	0.382974910187836	[]	[]	3	hSpCas9	negative selection	2688500
114709669	114709692	1	+	27260157	HT1080	viability	TTGTTTCCCACTAGCACCATAGG	NRAS	ENSG00000213281	-2.27963546481751	[]	[]	-9	hSpCas9	negative selection	2688525
114716136	114716159	1	-	27260157	HT1080	viability	GACTGAGTACAAACTGGTGGTGG	NRAS	ENSG00000213281	-3.33028552980179	[]	[]	-9	hSpCas9	negative selection	2688696
114713861	114713884	1	+	27260157	HT1080	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-4.08858339831352	[]	[]	-9	hSpCas9	negative selection	2690149
114708543	114708566	1	-	27260157	HT1080	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	-2.07510947934338	[]	[]	-9	hSpCas9	negative selection	2690304
114716116	114716139	1	-	27260157	HT1080	viability	TGGTTGGAGCAGGTGGTGTTGGG	NRAS	ENSG00000213281	-3.42030646228975	[]	[]	-9	hSpCas9	negative selection	2692745
114716139	114716162	1	-	27260157	HT1080	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	-2.94747031600331	[]	[]	-9	hSpCas9	negative selection	2698820
114713860	114713883	1	-	27260157	HT1080	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	-1.77597293638477	[]	[]	-9	hSpCas9	negative selection	2718797
114713871	114713894	1	+	27260157	HT1080	viability	CCTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	-4.05169909403909	[]	[]	-9	hSpCas9	negative selection	2723741
114708530	114708553	1	+	27260157	HT1080	viability	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	-3.33173705847407	[]	[]	-9	hSpCas9	negative selection	2724850
114709605	114709628	1	-	27260157	MKN45	viability	ACGAACTGGCCAAGAGTTACGGG	NRAS	ENSG00000213281	0.501357312784546	[]	[]	6	hSpCas9	negative selection	2727477
114716142	114716165	1	-	27260157	MKN45	viability	TGAAATGACTGAGTACAAACTGG	NRAS	ENSG00000213281	0.12177073782667	[]	[]	4	hSpCas9	negative selection	2727791
114713911	114713934	1	-	27260157	MKN45	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	1.49638349259441	[]	[]	9	hSpCas9	negative selection	2733767
114709685	114709708	1	-	27260157	MKN45	viability	AGACTCGGATGATGTACCTATGG	NRAS	ENSG00000213281	-0.274633680924359	[]	[]	-1	hSpCas9	negative selection	2733946
114708557	114708580	1	-	27260157	MKN45	viability	GATGGGACTCAGGGTTGTATGGG	NRAS	ENSG00000213281	-0.27681167868583	[]	[]	-1	hSpCas9	negative selection	2734080
114713871	114713894	1	-	27260157	MKN45	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.0102228110443229	[]	[]	0	hSpCas9	negative selection	2735689
114708567	114708590	1	-	27260157	MKN45	viability	CAGCAGTGATGATGGGACTCAGG	NRAS	ENSG00000213281	1.02386603119682	[]	[]	8	hSpCas9	negative selection	2737331
114709596	114709619	1	+	27260157	MKN45	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-0.577846748433131	[]	[]	-6	hSpCas9	negative selection	2756944
114709607	114709630	1	+	27260157	MKN45	viability	CGTAACTCTTGGCCAGTTCGTGG	NRAS	ENSG00000213281	-0.740118980217756	[]	[]	-7	hSpCas9	negative selection	2759716
114716076	114716099	1	+	27260157	MKN45	viability	CAAAGTGGTTCTGGATTAGCTGG	NRAS	ENSG00000213281	0.226360778011708	[]	[]	5	hSpCas9	negative selection	2762123
114713820	114713843	1	+	27260157	MKN45	viability	AAATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	1.18396611061213	[]	[]	8	hSpCas9	negative selection	2764630
114709669	114709692	1	+	27260157	MKN45	viability	TTGTTTCCCACTAGCACCATAGG	NRAS	ENSG00000213281	0.656554137014642	[]	[]	7	hSpCas9	negative selection	2764655
114716136	114716159	1	-	27260157	MKN45	viability	GACTGAGTACAAACTGGTGGTGG	NRAS	ENSG00000213281	0.0795216533317524	[]	[]	0	hSpCas9	negative selection	2764826
114713861	114713884	1	+	27260157	MKN45	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.172596043416562	[]	[]	5	hSpCas9	negative selection	2766279
114708543	114708566	1	-	27260157	MKN45	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	-1.1174613122357	[]	[]	-8	hSpCas9	negative selection	2766434
114716116	114716139	1	-	27260157	MKN45	viability	TGGTTGGAGCAGGTGGTGTTGGG	NRAS	ENSG00000213281	-0.860467084344456	[]	[]	-7	hSpCas9	negative selection	2768875
114716139	114716162	1	-	27260157	MKN45	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	0.0357021573912937	[]	[]	0	hSpCas9	negative selection	2774950
114713860	114713883	1	-	27260157	MKN45	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	0.266974283329663	[]	[]	5	hSpCas9	negative selection	2794927
114713871	114713894	1	+	27260157	MKN45	viability	CCTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	-0.27119186634398	[]	[]	-1	hSpCas9	negative selection	2799871
114708530	114708553	1	+	27260157	MKN45	viability	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.161637279016204	[]	[]	5	hSpCas9	negative selection	2800980
114709605	114709628	1	-	27260157	RKO	viability	ACGAACTGGCCAAGAGTTACGGG	NRAS	ENSG00000213281	0.542523039072544	[]	[]	3	hSpCas9	negative selection	2803607
114716142	114716165	1	-	27260157	RKO	viability	TGAAATGACTGAGTACAAACTGG	NRAS	ENSG00000213281	0.729661727235252	[]	[]	8	hSpCas9	negative selection	2803921
114713911	114713934	1	-	27260157	RKO	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	1.58445262471987	[]	[]	9	hSpCas9	negative selection	2809897
114709685	114709708	1	-	27260157	RKO	viability	AGACTCGGATGATGTACCTATGG	NRAS	ENSG00000213281	-0.357307378053374	[]	[]	-6	hSpCas9	negative selection	2810076
114708557	114708580	1	-	27260157	RKO	viability	GATGGGACTCAGGGTTGTATGGG	NRAS	ENSG00000213281	-1.01326154476725	[]	[]	-8	hSpCas9	negative selection	2810210
114713871	114713894	1	-	27260157	RKO	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.125218653286204	[]	[]	0	hSpCas9	negative selection	2811819
114708567	114708590	1	-	27260157	RKO	viability	CAGCAGTGATGATGGGACTCAGG	NRAS	ENSG00000213281	0.57003691350666	[]	[]	3	hSpCas9	negative selection	2813461
114709596	114709619	1	+	27260157	RKO	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.0483039459766585	[]	[]	0	hSpCas9	negative selection	2833074
114709607	114709630	1	+	27260157	RKO	viability	CGTAACTCTTGGCCAGTTCGTGG	NRAS	ENSG00000213281	-1.87831942813765	[]	[]	-9	hSpCas9	negative selection	2835846
114716076	114716099	1	+	27260157	RKO	viability	CAAAGTGGTTCTGGATTAGCTGG	NRAS	ENSG00000213281	0.231567569462335	[]	[]	1	hSpCas9	negative selection	2838253
114713820	114713843	1	+	27260157	RKO	viability	AAATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	0.332487939176467	[]	[]	1	hSpCas9	negative selection	2840760
114709669	114709692	1	+	27260157	RKO	viability	TTGTTTCCCACTAGCACCATAGG	NRAS	ENSG00000213281	-0.0799236381146312	[]	[]	0	hSpCas9	negative selection	2840785
114716136	114716159	1	-	27260157	RKO	viability	GACTGAGTACAAACTGGTGGTGG	NRAS	ENSG00000213281	-0.0317678253343959	[]	[]	0	hSpCas9	negative selection	2840956
114713861	114713884	1	+	27260157	RKO	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-1.03127689520197	[]	[]	-8	hSpCas9	negative selection	2842409
114708543	114708566	1	-	27260157	RKO	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	-0.203225041872877	[]	[]	-1	hSpCas9	negative selection	2842564
114716116	114716139	1	-	27260157	RKO	viability	TGGTTGGAGCAGGTGGTGTTGGG	NRAS	ENSG00000213281	-0.13880812446498	[]	[]	0	hSpCas9	negative selection	2845005
114716139	114716162	1	-	27260157	RKO	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	-0.327883870191487	[]	[]	-6	hSpCas9	negative selection	2851080
114713860	114713883	1	-	27260157	RKO	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	0.0049441672475032	[]	[]	0	hSpCas9	negative selection	2871057
114713871	114713894	1	+	27260157	RKO	viability	CCTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	-0.748392923162768	[]	[]	-7	hSpCas9	negative selection	2876001
114708530	114708553	1	+	27260157	RKO	viability	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	-0.531927551245265	[]	[]	-6	hSpCas9	negative selection	2877110
114709605	114709628	1	-	27260157	SF268	viability	ACGAACTGGCCAAGAGTTACGGG	NRAS	ENSG00000213281	-0.648055686763049	[]	[]	-5	hSpCas9	negative selection	2879737
114716142	114716165	1	-	27260157	SF268	viability	TGAAATGACTGAGTACAAACTGG	NRAS	ENSG00000213281	-0.222082243577369	[]	[]	-2	hSpCas9	negative selection	2880051
114713911	114713934	1	-	27260157	SF268	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	0.408832480459377	[]	[]	4	hSpCas9	negative selection	2886027
114709685	114709708	1	-	27260157	SF268	viability	AGACTCGGATGATGTACCTATGG	NRAS	ENSG00000213281	-0.412340734991146	[]	[]	-3	hSpCas9	negative selection	2886206
114708557	114708580	1	-	27260157	SF268	viability	GATGGGACTCAGGGTTGTATGGG	NRAS	ENSG00000213281	-1.21478368312349	[]	[]	-7	hSpCas9	negative selection	2886340
114713871	114713894	1	-	27260157	SF268	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-1.03879680469354	[]	[]	-7	hSpCas9	negative selection	2887949
114708567	114708590	1	-	27260157	SF268	viability	CAGCAGTGATGATGGGACTCAGG	NRAS	ENSG00000213281	0.2976571739664	[]	[]	4	hSpCas9	negative selection	2889591
114709596	114709619	1	+	27260157	SF268	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-1.43546002009866	[]	[]	-8	hSpCas9	negative selection	2909204
114709607	114709630	1	+	27260157	SF268	viability	CGTAACTCTTGGCCAGTTCGTGG	NRAS	ENSG00000213281	-0.987578633961042	[]	[]	-7	hSpCas9	negative selection	2911976
114716076	114716099	1	+	27260157	SF268	viability	CAAAGTGGTTCTGGATTAGCTGG	NRAS	ENSG00000213281	0.267915243344755	[]	[]	4	hSpCas9	negative selection	2914383
114713820	114713843	1	+	27260157	SF268	viability	AAATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	-0.145563125189651	[]	[]	-1	hSpCas9	negative selection	2916890
114709669	114709692	1	+	27260157	SF268	viability	TTGTTTCCCACTAGCACCATAGG	NRAS	ENSG00000213281	-0.653246794365048	[]	[]	-5	hSpCas9	negative selection	2916915
114716136	114716159	1	-	27260157	SF268	viability	GACTGAGTACAAACTGGTGGTGG	NRAS	ENSG00000213281	-1.45698876385715	[]	[]	-8	hSpCas9	negative selection	2917086
114713861	114713884	1	+	27260157	SF268	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-1.42989414186821	[]	[]	-8	hSpCas9	negative selection	2918539
114708543	114708566	1	-	27260157	SF268	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	-0.377338022371339	[]	[]	-3	hSpCas9	negative selection	2918694
114716116	114716139	1	-	27260157	SF268	viability	TGGTTGGAGCAGGTGGTGTTGGG	NRAS	ENSG00000213281	-0.524470423061538	[]	[]	-4	hSpCas9	negative selection	2921135
114716139	114716162	1	-	27260157	SF268	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	-1.27234760370765	[]	[]	-7	hSpCas9	negative selection	2927210
114713860	114713883	1	-	27260157	SF268	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	-0.694203783609206	[]	[]	-5	hSpCas9	negative selection	2947187
114713871	114713894	1	+	27260157	SF268	viability	CCTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	-1.92039762180329	[]	[]	-8	hSpCas9	negative selection	2952131
114708530	114708553	1	+	27260157	SF268	viability	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	-0.736210099993605	[]	[]	-5	hSpCas9	negative selection	2953240
114716139	114716162	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	-0.0052906005304629855	[5,5]	[4,3]	0	hSpCas9	positive selection	3006491
114716136	114716159	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACTGAGTACAAACTGGTGGTGG	NRAS	ENSG00000213281	0.014917512599401606	[2,3]	[1,3]	0	hSpCas9	positive selection	3006492
114713957	114713980	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATTCTTACAGAAAACAAGTGG	NRAS	ENSG00000213281	0.2284605132766335	[2,2]	[3,1]	5	hSpCas9	positive selection	3006493
114713835	114713858	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATTGATGGCAAATACACAGAGG	NRAS	ENSG00000213281	0.15268205258412762	[3,3]	[3,3]	3	hSpCas9	positive selection	3006494
114716139	114716162	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	0.25391604718321337	[5,5]	[5,3]	4	hSpCas9	positive selection	3074349
114716136	114716159	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACTGAGTACAAACTGGTGGTGG	NRAS	ENSG00000213281	0.4801658617310479	[2,2]	[2,2]	7	hSpCas9	positive selection	3074350
114713957	114713980	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATTCTTACAGAAAACAAGTGG	NRAS	ENSG00000213281	0.9460941045296092	[2,2]	[2,4]	9	hSpCas9	positive selection	3074351
114713835	114713858	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATTGATGGCAAATACACAGAGG	NRAS	ENSG00000213281	-0.825664598227426	[3,3]	[1,0]	-9	hSpCas9	positive selection	3074352
114713871	114713894		-	24336571	A375	resistance to PLX after 7 days	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.32069175444172626	[4,3]	[4,5]	8	hSpCas9	positive selection	3131566
114713861	114713884		+	24336571	A375	resistance to PLX after 7 days	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.22162574620857112	[21,22]	[28,22]	6	hSpCas9	positive selection	3131567
114709596	114709619		+	24336571	A375	resistance to PLX after 7 days	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-0.2336019635371717	[10,10]	[7,9]	-7	hSpCas9	positive selection	3131568
114709619	114709642		-	24336571	A375	resistance to PLX after 7 days	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.11335031978623289	[4,3]	[4,3]	-4	hSpCas9	positive selection	3131569
114713871	114713894		-	24336571	A375	resistance to PLX after 14 days	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	1.2131619553340567	[6,3]	[5,5]	8	hSpCas9	positive selection	3189359
114713861	114713884		+	24336571	A375	resistance to PLX after 14 days	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	1.1235651331213892	[23,24]	[23,25]	8	hSpCas9	positive selection	3189360
114709596	114709619		+	24336571	A375	resistance to PLX after 14 days	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.21511627235828615	[10,11]	[4,6]	2	hSpCas9	positive selection	3189361
114709619	114709642		-	24336571	A375	resistance to PLX after 14 days	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.2497539267356994	[6,5]	[1,2]	-3	hSpCas9	positive selection	3189362
114713871	114713894		-	24336571	A375	viability after 7 days	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.7614106167955237	[2]	[4,3]	9	hSpCas9	negative selection	3247152
114713861	114713884		+	24336571	A375	viability after 7 days	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.37396110179471037	[17]	[21,22]	6	hSpCas9	negative selection	3247153
114709596	114709619		+	24336571	A375	viability after 7 days	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.078885837634569	[10]	[10,10]	1	hSpCas9	negative selection	3247154
114709619	114709642		-	24336571	A375	viability after 7 days	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.9048710978408493	[9]	[4,3]	-8	hSpCas9	negative selection	3247155
114713871	114713894		-	24336571	A375	viability after 14 days	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.9687193272645849	[2]	[6,3]	9	hSpCas9	negative selection	3304945
114713861	114713884		+	24336571	A375	viability after 14 days	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.5244944312610955	[17]	[23,24]	6	hSpCas9	negative selection	3304946
114709596	114709619		+	24336571	A375	viability after 14 days	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.15202720715426382	[10]	[10,11]	2	hSpCas9	negative selection	3304947
114709619	114709642		-	24336571	A375	viability after 14 days	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.48335336032892917	[9]	[6,5]	-5	hSpCas9	negative selection	3304948
114713871	114713894	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.5240335020788246	[219,219]	[0,0]	-3	hSpCas9	positive selection	3382364
114713861	114713884	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	1.3031299010589596	[61,61]	[0,0]	5	hSpCas9	positive selection	3382365
114716067	114716090	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	0.11777485904704146	[140,140]	[0,0]	0	hSpCas9	positive selection	3382366
114716139	114716162	1	-	26780180	HT29	viability (Avana library 4 designs)	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	0.492272620412167	[]	[]	1	hSpCas9	negative selection	3444380
114716136	114716159	1	-	26780180	HT29	viability (Avana library 4 designs)	GACTGAGTACAAACTGGTGGTGG	NRAS	ENSG00000213281	2.13042218646086	[]	[]	7	hSpCas9	negative selection	3444381
114713957	114713980	1	-	26780180	HT29	viability (Avana library 4 designs)	GGATTCTTACAGAAAACAAGTGG	NRAS	ENSG00000213281	1.52734998918346	[]	[]	6	hSpCas9	negative selection	3444382
114713834	114713857	1	+	26780180	HT29	viability (Avana library 4 designs)	TATTGATGGCAAATACACAGAGG	NRAS	ENSG00000213281	0.8027412618827	[]	[]	3	hSpCas9	negative selection	3444383
114713957	114713980	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATTCTTACAGAAAACAAGTGG	NRAS	ENSG00000213281	-16.1073876144852	[]	[]	-9	hSpCas9	negative selection	3536585
114716136	114716159	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACTGAGTACAAACTGGTGGTGG	NRAS	ENSG00000213281	1.31804411257656	[]	[]	1	hSpCas9	negative selection	3536586
114713834	114713857	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TATTGATGGCAAATACACAGAGG	NRAS	ENSG00000213281	-8.57919613488522	[]	[]	-7	hSpCas9	negative selection	3536587
114716139	114716162	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	-2.02655248634137	[]	[]	-2	hSpCas9	negative selection	3536588
114716061	114716084	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATCATATTCATCTACAAAGTGG	NRAS	ENSG00000213281	-7.13532038753522	[]	[]	-6	hSpCas9	negative selection	3536589
114716049	114716072	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	-7.01826301842452	[]	[]	-6	hSpCas9	negative selection	3536590
114713957	114713980	1	-	26780180	A375	viability (Avana lentiGuide)	GGATTCTTACAGAAAACAAGTGG	NRAS	ENSG00000213281	0.471036413493088	[]	[]	0	hSpCas9	negative selection	3645244
114716136	114716159	1	-	26780180	A375	viability (Avana lentiGuide)	GACTGAGTACAAACTGGTGGTGG	NRAS	ENSG00000213281	-0.988313474423335	[]	[]	-1	hSpCas9	negative selection	3645245
114713834	114713857	1	+	26780180	A375	viability (Avana lentiGuide)	TATTGATGGCAAATACACAGAGG	NRAS	ENSG00000213281	-1.30187111262875	[]	[]	-2	hSpCas9	negative selection	3645246
114716139	114716162	1	-	26780180	A375	viability (Avana lentiGuide)	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	0.307335255712618	[]	[]	0	hSpCas9	negative selection	3645247
114716061	114716084	1	+	26780180	A375	viability (Avana lentiGuide)	GATCATATTCATCTACAAAGTGG	NRAS	ENSG00000213281	8.84231633726623	[]	[]	6	hSpCas9	negative selection	3645248
114716049	114716072	1	-	26780180	A375	viability (Avana lentiGuide)	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	5.63024974303207	[]	[]	5	hSpCas9	negative selection	3645249
114713957	114713980	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATTCTTACAGAAAACAAGTGG	NRAS	ENSG00000213281	-1.0985562755903038	[5]	[2,1]	-9	hSpCas9	positive selection	3753903
114716136	114716159	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACTGAGTACAAACTGGTGGTGG	NRAS	ENSG00000213281	0.20372844981463806	[4]	[5,5]	5	hSpCas9	positive selection	3753904
114713834	114713857	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATTGATGGCAAATACACAGAGG	NRAS	ENSG00000213281	-0.7466792884671516	[5]	[3,2]	-8	hSpCas9	positive selection	3753905
114716139	114716162	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	-0.026075726312862868	[6]	[6,5]	0	hSpCas9	positive selection	3753906
114716061	114716084	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCATATTCATCTACAAAGTGG	NRAS	ENSG00000213281	-1.0720386781801823	[9]	[3,3]	-9	hSpCas9	positive selection	3753907
114716049	114716072	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	-0.4069856649664906	[7]	[5,4]	-6	hSpCas9	positive selection	3753908
114713957	114713980	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATTCTTACAGAAAACAAGTGG	NRAS	ENSG00000213281	0.1462837549252525	[4]	[5,3]	3	hSpCas9	positive selection	3862510
114716136	114716159	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACTGAGTACAAACTGGTGGTGG	NRAS	ENSG00000213281	-0.11806706577513423	[4]	[4,2]	-2	hSpCas9	positive selection	3862511
114713834	114713857	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATTGATGGCAAATACACAGAGG	NRAS	ENSG00000213281	-0.028317196139275552	[4]	[5,1]	0	hSpCas9	positive selection	3862512
114716139	114716162	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	0.25369350508050786	[7]	[7,7]	6	hSpCas9	positive selection	3862513
114716061	114716084	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCATATTCATCTACAAAGTGG	NRAS	ENSG00000213281	0.4261461905129854	[5]	[6,5]	9	hSpCas9	positive selection	3862514
114716049	114716072	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	-0.1818914721795029	[5]	[5,2]	-3	hSpCas9	positive selection	3862515
114716067	114716090	1	+	26780180	A375	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	1.65170233324243	[]	[]	8	hSpCas9	negative selection	3973706
114713871	114713894	1	-	26780180	A375	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	1.23705868441034	[]	[]	6	hSpCas9	negative selection	3973707
114713861	114713884	1	+	26780180	A375	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	1.44201973536056	[]	[]	8	hSpCas9	negative selection	3973708
114709596	114709619	1	+	26780180	A375	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	1.59408143594707	[]	[]	8	hSpCas9	negative selection	3973709
114709619	114709642	1	-	26780180	A375	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	1.75380223033924	[]	[]	9	hSpCas9	negative selection	3973710
114708543	114708566	1	-	26780180	A375	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.638023096539415	[]	[]	2	hSpCas9	negative selection	3973711
114716067	114716090	1	+	26780180	HT29	viability (GeCKOv2 library)	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	1.35960632485309	[]	[]	7	hSpCas9	negative selection	4081672
114713871	114713894	1	-	26780180	HT29	viability (GeCKOv2 library)	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	1.02005536194855	[]	[]	4	hSpCas9	negative selection	4081673
114713861	114713884	1	+	26780180	HT29	viability (GeCKOv2 library)	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	1.27936795214909	[]	[]	6	hSpCas9	negative selection	4081674
114709596	114709619	1	+	26780180	HT29	viability (GeCKOv2 library)	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	1.32315977661485	[]	[]	6	hSpCas9	negative selection	4081675
114709619	114709642	1	-	26780180	HT29	viability (GeCKOv2 library)	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	1.40041339400089	[]	[]	7	hSpCas9	negative selection	4081676
114708543	114708566	1	-	26780180	HT29	viability (GeCKOv2 library)	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	1.28124456414573	[]	[]	6	hSpCas9	negative selection	4081677
114713871	114713894	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.1065387365319646	[3]	[2,2]	2	hSpCas9	positive selection	4156271
114713861	114713884	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.4692014502492201	[4]	[3,4]	8	hSpCas9	positive selection	4156272
114709596	114709619	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-0.07021206447110499	[3]	[1,2]	-2	hSpCas9	positive selection	4156273
114709619	114709642	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	0.0656751020965346	[1]	[1,0]	1	hSpCas9	positive selection	4156274
114713871	114713894	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.6531090988579107	[2]	[4,1,2,0]	4	hSpCas9	positive selection	4220293
114713861	114713884	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.039859265864596816	[4]	[3,4,1,0]	0	hSpCas9	positive selection	4220294
114709596	114709619	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.7323753127078568	[1]	[2,1,0,0]	5	hSpCas9	positive selection	4220295
114709619	114709642	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	0.27947095760855317	[2]	[0,3,1,0]	2	hSpCas9	positive selection	4220296
114709619	114709642	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	0.13351426988791482	[3]	[2,3]	2	hSpCas9	positive selection	4286304
114709596	114709619	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-0.5796588910510682	[3]	[3,0]	-8	hSpCas9	positive selection	4286305
114708543	114708566	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.007706151621684282	[3]	[3,1]	0	hSpCas9	positive selection	4286306
114713871	114713894	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.013433326873784873	[3]	[3,1]	0	hSpCas9	positive selection	4350561
114713861	114713884	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.07091720303380428	[2]	[2,1]	1	hSpCas9	positive selection	4350562
114716067	114716090	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.032084852446720796	[3]	[2,1]	0	hSpCas9	positive selection	4350563
114709700	114709722	1	-	27760321	OCIAML3	viability	ATTAAGCGAGTAAAAGACTCGG	NRAS	ENSG00000213281	-4.969104173394568	[40,38]	[0,0]	-9	hSpCas9	negative selection	4423450
114713821	114713843	1	+	27760321	OCIAML3	viability	AATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	-4.183919916524327	[20,24]	[0,0]	-9	hSpCas9	negative selection	4423451
114713872	114713894	1	+	27760321	OCIAML3	viability	CTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	-1.562922521416084	[312,268]	[35,129]	-8	hSpCas9	negative selection	4423452
114713947	114713969	1	-	27760321	OCIAML3	viability	GAAAACAAGTGGTTATAGATGG	NRAS	ENSG00000213281	-2.381470069231728	[25,17]	[4,0]	-9	hSpCas9	negative selection	4423453
114716036	114716058	1	+	27760321	OCIAML3	viability	CCACTGGGCCTCACCTCTATGG	NRAS	ENSG00000213281	-2.5887178886342306	[737,552]	[77,89]	-9	hSpCas9	negative selection	4423454
114709700	114709722	1	-	27760321	OCIAML2	viability	ATTAAGCGAGTAAAAGACTCGG	NRAS	ENSG00000213281	-0.18149793586725194	[40,38]	[28,27]	-2	hSpCas9	negative selection	4506913
114713821	114713843	1	+	27760321	OCIAML2	viability	AATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	0.3370012735296313	[20,24]	[18,29]	4	hSpCas9	negative selection	4506914
114713872	114713894	1	+	27760321	OCIAML2	viability	CTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	0.2981158689266337	[312,268]	[263,320]	4	hSpCas9	negative selection	4506915
114713947	114713969	1	-	27760321	OCIAML2	viability	GAAAACAAGTGGTTATAGATGG	NRAS	ENSG00000213281	1.7827231025246864	[25,17]	[25,105]	9	hSpCas9	negative selection	4506916
114716036	114716058	1	+	27760321	OCIAML2	viability	CCACTGGGCCTCACCTCTATGG	NRAS	ENSG00000213281	-0.282661374405661	[737,552]	[353,519]	-3	hSpCas9	negative selection	4506917
114709700	114709722	1	-	27760321	MV411	viability	ATTAAGCGAGTAAAAGACTCGG	NRAS	ENSG00000213281	-1.689452455932459	[40,38]	[0,18]	-8	hSpCas9	negative selection	4590376
114713821	114713843	1	+	27760321	MV411	viability	AATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	-3.938841347609645	[20,24]	[0,0]	-9	hSpCas9	negative selection	4590377
114713872	114713894	1	+	27760321	MV411	viability	CTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	1.2492259206255167	[312,268]	[154,905]	8	hSpCas9	negative selection	4590378
114713947	114713969	1	-	27760321	MV411	viability	GAAAACAAGTGGTTATAGATGG	NRAS	ENSG00000213281	-3.842860305815506	[25,17]	[0,0]	-9	hSpCas9	negative selection	4590379
114716036	114716058	1	+	27760321	MV411	viability	CCACTGGGCCTCACCTCTATGG	NRAS	ENSG00000213281	0.10463374835713468	[737,552]	[603,228]	0	hSpCas9	negative selection	4590380
114709700	114709722	1	-	27760321	HL60	viability	ATTAAGCGAGTAAAAGACTCGG	NRAS	ENSG00000213281	-5.0318957662740225	[40,38]	[0,0]	-9	hSpCas9	negative selection	4673839
114713821	114713843	1	+	27760321	HL60	viability	AATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	1.0753674871144785	[20,24]	[6,74]	9	hSpCas9	negative selection	4673840
114713872	114713894	1	+	27760321	HL60	viability	CTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	-1.5440852325342105	[312,268]	[106,53]	-8	hSpCas9	negative selection	4673841
114713947	114713969	1	-	27760321	HL60	viability	GAAAACAAGTGGTTATAGATGG	NRAS	ENSG00000213281	-0.9667888877860298	[25,17]	[11,5]	-7	hSpCas9	negative selection	4673842
114716036	114716058	1	+	27760321	HL60	viability	CCACTGGGCCTCACCTCTATGG	NRAS	ENSG00000213281	-2.9382855452247645	[737,552]	[41,95]	-9	hSpCas9	negative selection	4673843
114709700	114709722	1	-	27760321	HT1080	viability	ATTAAGCGAGTAAAAGACTCGG	NRAS	ENSG00000213281	-3.8031003095098503	[38,30]	[0,0]	-8	hSpCas9	negative selection	4757302
114713821	114713843	1	+	27760321	HT1080	viability	AATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	-3.166245333808321	[24,19]	[0,0]	-7	hSpCas9	negative selection	4757303
114713872	114713894	1	+	27760321	HT1080	viability	CTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	-6.576088312889056	[268,209]	[0,0]	-9	hSpCas9	negative selection	4757304
114713947	114713969	1	-	27760321	HT1080	viability	GAAAACAAGTGGTTATAGATGG	NRAS	ENSG00000213281	-2.671875160129228	[17,13]	[0,0]	-7	hSpCas9	negative selection	4757305
114716036	114716058	1	+	27760321	HT1080	viability	CCACTGGGCCTCACCTCTATGG	NRAS	ENSG00000213281	-7.009663797352274	[552,431]	[1,0]	-9	hSpCas9	negative selection	4757306
114709700	114709722	1	-	27760321	HT29	viability after 7 days	ATTAAGCGAGTAAAAGACTCGG	NRAS	ENSG00000213281	0.4284393491177316	[38,30]	[15,84,73]	6	hSpCas9	negative selection	4840765
114713821	114713843	1	+	27760321	HT29	viability after 7 days	AATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	0.7746262842901426	[24,19]	[59,36,52]	9	hSpCas9	negative selection	4840766
114713872	114713894	1	+	27760321	HT29	viability after 7 days	CTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	-0.40107266769077277	[268,209]	[434,217,79]	-5	hSpCas9	negative selection	4840767
114713947	114713969	1	-	27760321	HT29	viability after 7 days	GAAAACAAGTGGTTATAGATGG	NRAS	ENSG00000213281	1.0591614827879994	[17,13]	[25,53,45]	9	hSpCas9	negative selection	4840768
114716036	114716058	1	+	27760321	HT29	viability after 7 days	CCACTGGGCCTCACCTCTATGG	NRAS	ENSG00000213281	0.5579584701901596	[552,431]	[797,877,1094]	8	hSpCas9	negative selection	4840769
114709700	114709722	1	-	27760321	HT29	viability after 25 days	ATTAAGCGAGTAAAAGACTCGG	NRAS	ENSG00000213281	-4.902757413504569	[38,30]	[0,1,0]	-9	hSpCas9	negative selection	4924228
114713821	114713843	1	+	27760321	HT29	viability after 25 days	AATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	-0.3470387283535721	[24,19]	[7,45,5]	-3	hSpCas9	negative selection	4924229
114713872	114713894	1	+	27760321	HT29	viability after 25 days	CTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	0.1601974326871869	[268,209]	[308,283,325]	1	hSpCas9	negative selection	4924230
114713947	114713969	1	-	27760321	HT29	viability after 25 days	GAAAACAAGTGGTTATAGATGG	NRAS	ENSG00000213281	-3.7715322641239464	[17,13]	[0,1,0]	-9	hSpCas9	negative selection	4924231
114716036	114716058	1	+	27760321	HT29	viability after 25 days	CCACTGGGCCTCACCTCTATGG	NRAS	ENSG00000213281	0.08056208343214805	[552,431]	[766,513,480]	0	hSpCas9	negative selection	4924232
114709700	114709722	1	-	27760321	HT29	viability after 22 days	ATTAAGCGAGTAAAAGACTCGG	NRAS	ENSG00000213281	-2.6102847094895427	[38,30]	[0,17,0]	-8	hSpCas9	negative selection	5007691
114713821	114713843	1	+	27760321	HT29	viability after 22 days	AATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	-0.4294951522769517	[24,19]	[13,42,0]	-4	hSpCas9	negative selection	5007692
114713872	114713894	1	+	27760321	HT29	viability after 22 days	CTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	0.4101854883313878	[268,209]	[571,185,339]	4	hSpCas9	negative selection	5007693
114713947	114713969	1	-	27760321	HT29	viability after 22 days	GAAAACAAGTGGTTATAGATGG	NRAS	ENSG00000213281	-0.8512135254800235	[17,13]	[0,19,9]	-6	hSpCas9	negative selection	5007694
114716036	114716058	1	+	27760321	HT29	viability after 22 days	CCACTGGGCCTCACCTCTATGG	NRAS	ENSG00000213281	0.3913376539200755	[552,431]	[1187,448,589]	4	hSpCas9	negative selection	5007695
114709700	114709722	1	-	27760321	HT29	viability after 19 days	ATTAAGCGAGTAAAAGACTCGG	NRAS	ENSG00000213281	-2.0317791560105354	[38,30]	[0,4,21]	-8	hSpCas9	negative selection	5091154
114713821	114713843	1	+	27760321	HT29	viability after 19 days	AATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	-1.1665829220330584	[24,19]	[12,20,0]	-7	hSpCas9	negative selection	5091155
114713872	114713894	1	+	27760321	HT29	viability after 19 days	CTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	0.4278605991857052	[268,209]	[662,237,239]	4	hSpCas9	negative selection	5091156
114713947	114713969	1	-	27760321	HT29	viability after 19 days	GAAAACAAGTGGTTATAGATGG	NRAS	ENSG00000213281	0.41516460212439643	[17,13]	[22,24,24]	4	hSpCas9	negative selection	5091157
114716036	114716058	1	+	27760321	HT29	viability after 19 days	CCACTGGGCCTCACCTCTATGG	NRAS	ENSG00000213281	0.5912166100463854	[552,431]	[693,528,1288]	6	hSpCas9	negative selection	5091158
114709700	114709722	1	-	27760321	HT29	viability after 16 days	ATTAAGCGAGTAAAAGACTCGG	NRAS	ENSG00000213281	-2.495740636158903	[38,30]	[0,17,0]	-8	hSpCas9	negative selection	5174617
114713821	114713843	1	+	27760321	HT29	viability after 16 days	AATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	-0.46581461195750284	[24,19]	[6,44,0]	-5	hSpCas9	negative selection	5174618
114713872	114713894	1	+	27760321	HT29	viability after 16 days	CTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	0.37673409936751223	[268,209]	[380,340,324]	4	hSpCas9	negative selection	5174619
114713947	114713969	1	-	27760321	HT29	viability after 16 days	GAAAACAAGTGGTTATAGATGG	NRAS	ENSG00000213281	0.9751773671719679	[17,13]	[95,7,7]	9	hSpCas9	negative selection	5174620
114716036	114716058	1	+	27760321	HT29	viability after 16 days	CCACTGGGCCTCACCTCTATGG	NRAS	ENSG00000213281	0.4465652478131215	[552,431]	[674,772,796]	5	hSpCas9	negative selection	5174621
114709700	114709722	1	-	27760321	HT29	viability after 13 days	ATTAAGCGAGTAAAAGACTCGG	NRAS	ENSG00000213281	-1.4831535358105237	[38,30]	[25,9,7]	-8	hSpCas9	negative selection	5258080
114713821	114713843	1	+	27760321	HT29	viability after 13 days	AATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	-0.05756695542425527	[24,19]	[19,23,30]	0	hSpCas9	negative selection	5258081
114713872	114713894	1	+	27760321	HT29	viability after 13 days	CTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	0.3665261330206482	[268,209]	[522,325,232]	4	hSpCas9	negative selection	5258082
114713947	114713969	1	-	27760321	HT29	viability after 13 days	GAAAACAAGTGGTTATAGATGG	NRAS	ENSG00000213281	0.4615962547660981	[17,13]	[0,71,4]	6	hSpCas9	negative selection	5258083
114716036	114716058	1	+	27760321	HT29	viability after 13 days	CCACTGGGCCTCACCTCTATGG	NRAS	ENSG00000213281	0.3922146117035226	[552,431]	[571,928,748]	5	hSpCas9	negative selection	5258084
114709700	114709722	1	-	27760321	HT29	viability after 10 days	ATTAAGCGAGTAAAAGACTCGG	NRAS	ENSG00000213281	-0.593894737837986	[38,30]	[1,41,42]	-6	hSpCas9	negative selection	5341543
114713821	114713843	1	+	27760321	HT29	viability after 10 days	AATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	-0.034811135516785274	[24,19]	[8,67,6]	0	hSpCas9	negative selection	5341544
114713872	114713894	1	+	27760321	HT29	viability after 10 days	CTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	-0.20704513550198111	[268,209]	[190,286,298]	-3	hSpCas9	negative selection	5341545
114713947	114713969	1	-	27760321	HT29	viability after 10 days	GAAAACAAGTGGTTATAGATGG	NRAS	ENSG00000213281	0.6550584127650971	[17,13]	[83,0,8]	8	hSpCas9	negative selection	5341546
114716036	114716058	1	+	27760321	HT29	viability after 10 days	CCACTGGGCCTCACCTCTATGG	NRAS	ENSG00000213281	0.6446394362697783	[552,431]	[822,1163,903]	8	hSpCas9	negative selection	5341547
114709700	114709722	1	-	27760321	MOLM13	viability	ATTAAGCGAGTAAAAGACTCGG	NRAS	ENSG00000213281	0.891794271492178	[40,38]	[89,0]	6	hSpCas9	negative selection	5425006
114713821	114713843	1	+	27760321	MOLM13	viability	AATGACTTGCTATTATTGATGG	NRAS	ENSG00000213281	-0.01725574369448779	[20,24]	[26,0]	0	hSpCas9	negative selection	5425007
114713872	114713894	1	+	27760321	MOLM13	viability	CTCATGTATTGGTCTCTCATGG	NRAS	ENSG00000213281	1.3894223661865412	[312,268]	[450,409]	8	hSpCas9	negative selection	5425008
114713947	114713969	1	-	27760321	MOLM13	viability	GAAAACAAGTGGTTATAGATGG	NRAS	ENSG00000213281	-3.616803492987911	[25,17]	[0,0]	-9	hSpCas9	negative selection	5425009
114716036	114716058	1	+	27760321	MOLM13	viability	CCACTGGGCCTCACCTCTATGG	NRAS	ENSG00000213281	0.8558124771553428	[737,552]	[417,853]	6	hSpCas9	negative selection	5425010
114716721	114716744	1	-	27661255	K562	viability	GGCTGTTCATGGCGGTTCCGGGG	NRAS	ENSG00000213281	0.4201345419467305	[997,886]	[995,1020]	9	dCas9-KRAB	negative selection	5497455
114716742	114716765	1	-	27661255	K562	viability	GAAGTGCCGCTCCTTGGTGGGGG	NRAS	ENSG00000213281	0.13036706269093146	[372,327]	[331,285]	4	dCas9-KRAB	negative selection	5497456
114716774	114716797	1	-	27661255	K562	viability	GGCGCCGACTGATTACGTAGCGG	NRAS	ENSG00000213281	0.021210618280470772	[251,328]	[242,226]	0	dCas9-KRAB	negative selection	5497457
114709619	114709642	1	-	27260156	BXPC3	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.12349505365179292	[889]	[802,671,811,1179]	-3	hSpCas9	negative selection	5558764
114709596	114709619	1	+	27260156	BXPC3	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.33732553863498055	[624]	[859,810,648,990]	7	hSpCas9	negative selection	5558765
114708543	114708566	1	-	27260156	BXPC3	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.16547063117333224	[549]	[560,664,576,797]	3	hSpCas9	negative selection	5558766
114713871	114713894	1	-	27260156	BXPC3	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.0283292405333731	[544]	[606,488,576,556]	0	hSpCas9	negative selection	5623021
114713861	114713884	1	+	27260156	BXPC3	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.22223928345023447	[232]	[236,251,257,409]	5	hSpCas9	negative selection	5623022
114716067	114716090	1	+	27260156	BXPC3	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.14972246571965744	[480]	[433,511,341,527]	-3	hSpCas9	negative selection	5623023
114709619	114709642	1	-	27260156	A673	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.2982198566667602	[889]	[892,1018,810,743]	-6	hSpCas9	negative selection	5680015
114709596	114709619	1	+	27260156	A673	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.2333105279194267	[624]	[978,922,844,784]	5	hSpCas9	negative selection	5680016
114708543	114708566	1	-	27260156	A673	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.09913695372354517	[549]	[773,579,608,886]	2	hSpCas9	negative selection	5680017
114713871	114713894	1	-	27260156	A673	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.3444340847662314	[544]	[619,583,445,415]	-7	hSpCas9	negative selection	5744272
114713861	114713884	1	+	27260156	A673	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.04737124928010372	[232]	[305,239,288,250]	-1	hSpCas9	negative selection	5744273
114716067	114716090	1	+	27260156	A673	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.3308386191361282	[480]	[632,386,357,481]	-7	hSpCas9	negative selection	5744274
114709619	114709642	1	-	27260156	A375	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.5588309992916225	[889]	[698,975,453,725]	-6	hSpCas9	negative selection	5801266
114709596	114709619	1	+	27260156	A375	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.04897631541928793	[624]	[907,792,759,583]	0	hSpCas9	negative selection	5801267
114708543	114708566	1	-	27260156	A375	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.11670547316408789	[549]	[572,1006,644,610]	1	hSpCas9	negative selection	5801268
114713871	114713894	1	-	27260156	A375	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.4183605353151346	[544]	[506,517,357,520]	-5	hSpCas9	negative selection	5865523
114713861	114713884	1	+	27260156	A375	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.08634227626389213	[232]	[377,160,216,255]	-1	hSpCas9	negative selection	5865524
114716067	114716090	1	+	27260156	A375	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.31303597741583944	[480]	[479,661,283,414]	-4	hSpCas9	negative selection	5865525
114709619	114709642	1	-	27260156	COLO741	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.23322419014458473	[889]	[1229,782,912]	-5	hSpCas9	negative selection	5922517
114709596	114709619	1	+	27260156	COLO741	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.3532173865641422	[624]	[887,1346,826]	7	hSpCas9	negative selection	5922518
114708543	114708566	1	-	27260156	COLO741	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	-0.14657699171583405	[549]	[581,768,553]	-3	hSpCas9	negative selection	5922519
114713871	114713894	1	-	27260156	COLO741	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.3431466378523848	[544]	[668,457,529]	-6	hSpCas9	negative selection	5986774
114713861	114713884	1	+	27260156	COLO741	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.10224022195154814	[232]	[353,237,247]	-2	hSpCas9	negative selection	5986775
114716067	114716090	1	+	27260156	COLO741	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.2610239129611431	[480]	[554,515,472]	-5	hSpCas9	negative selection	5986776
114709619	114709642	1	-	27260156	CAL120	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.8908906568485974	[889]	[789,515,515]	-8	hSpCas9	negative selection	6043768
114709596	114709619	1	+	27260156	CAL120	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.25159695143407285	[624]	[1207,751,860]	4	hSpCas9	negative selection	6043769
114708543	114708566	1	-	27260156	CAL120	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.23470305200386002	[549]	[979,716,745]	3	hSpCas9	negative selection	6043770
114713871	114713894	1	-	27260156	CAL120	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.4797165611713674	[544]	[814,470,226]	-6	hSpCas9	negative selection	6108025
114713861	114713884	1	+	27260156	CAL120	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.34295219659714227	[232]	[198,183,296]	-5	hSpCas9	negative selection	6108026
114716067	114716090	1	+	27260156	CAL120	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	0.3537815728648537	[480]	[918,826,574]	5	hSpCas9	negative selection	6108027
114709619	114709642	1	-	27260156	CADOES1	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.13092783056533253	[889]	[692,779,742,809]	-2	hSpCas9	negative selection	6165019
114709596	114709619	1	+	27260156	CADOES1	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.19969868661273266	[624]	[497,646,747,781]	3	hSpCas9	negative selection	6165020
114708543	114708566	1	-	27260156	CADOES1	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.31546215727351823	[549]	[769,610,600,560]	5	hSpCas9	negative selection	6165021
114713871	114713894	1	-	27260156	CADOES1	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.4455905270890775	[544]	[359,425,328,373]	-7	hSpCas9	negative selection	6229276
114713861	114713884	1	+	27260156	CADOES1	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.07397473614921224	[232]	[209,133,204,276]	-1	hSpCas9	negative selection	6229277
114716067	114716090	1	+	27260156	CADOES1	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	0.22134085911624685	[480]	[385,830,454,410]	4	hSpCas9	negative selection	6229278
114709619	114709642	1	-	27260156	EWS502	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.32203854746945315	[889]	[1127,489,711,639]	-5	hSpCas9	negative selection	6286270
114709596	114709619	1	+	27260156	EWS502	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.2361173659552233	[624]	[900,712,801,680]	4	hSpCas9	negative selection	6286271
114708543	114708566	1	-	27260156	EWS502	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	-0.22209295332623863	[549]	[414,541,515,533]	-4	hSpCas9	negative selection	6286272
114713871	114713894	1	-	27260156	EWS502	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.7678201598938952	[544]	[377,339,297,332]	-8	hSpCas9	negative selection	6350527
114713861	114713884	1	+	27260156	EWS502	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.009420048471671327	[232]	[192,186,286,327]	0	hSpCas9	negative selection	6350528
114716067	114716090	1	+	27260156	EWS502	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.08063851125868376	[480]	[455,364,522,597]	-1	hSpCas9	negative selection	6350529
114709619	114709642	1	-	27260156	EW8	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.31670170782425544	[889]	[712,572,343,738]	-5	hSpCas9	negative selection	6407521
114709596	114709619	1	+	27260156	EW8	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.268241203605388	[624]	[506,787,489,662]	5	hSpCas9	negative selection	6407522
114708543	114708566	1	-	27260156	EW8	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	-0.03481419908203573	[549]	[615,360,374,416]	0	hSpCas9	negative selection	6407523
114713871	114713894	1	-	27260156	EW8	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.24233159177080973	[544]	[506,339,278,396]	-4	hSpCas9	negative selection	6471778
114713861	114713884	1	+	27260156	EW8	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.1255241455376781	[232]	[136,133,193,218]	-2	hSpCas9	negative selection	6471779
114716067	114716090	1	+	27260156	EW8	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.17186985873551153	[480]	[500,352,265,293]	-3	hSpCas9	negative selection	6471780
114709619	114709642	1	-	27260156	CORL105	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.1722848588750433	[889]	[807,783,1312,852]	-3	hSpCas9	negative selection	6528772
114709596	114709619	1	+	27260156	CORL105	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.054319327047427646	[624]	[771,681,900,707]	1	hSpCas9	negative selection	6528773
114708543	114708566	1	-	27260156	CORL105	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.3950956953990392	[549]	[754,853,690,1057]	7	hSpCas9	negative selection	6528774
114713871	114713894	1	-	27260156	CORL105	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.32489644461685135	[544]	[429,631,425,530]	-5	hSpCas9	negative selection	6593029
114713861	114713884	1	+	27260156	CORL105	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.3488307152485577	[232]	[299,100,265,202]	-6	hSpCas9	negative selection	6593030
114716067	114716090	1	+	27260156	CORL105	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.10152063085179706	[480]	[381,488,685,562]	-2	hSpCas9	negative selection	6593031
114709619	114709642	1	-	27260156	HS294T	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	0.048631928950877534	[889]	[346,312,317,464]	0	hSpCas9	negative selection	6650023
114709596	114709619	1	+	27260156	HS294T	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.3773193540571738	[624]	[304,228,321,419]	5	hSpCas9	negative selection	6650024
114708543	114708566	1	-	27260156	HS294T	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.4414578996306412	[549]	[284,285,207,392]	6	hSpCas9	negative selection	6650025
114713871	114713894	1	-	27260156	HS294T	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.21097703113496227	[544]	[180,158,188,202]	-3	hSpCas9	negative selection	6714280
114713861	114713884	1	+	27260156	HS294T	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.47711494619562456	[232]	[65,76,45,69]	-6	hSpCas9	negative selection	6714281
114716067	114716090	1	+	27260156	HS294T	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.5229500444086551	[480]	[87,136,146,152]	-6	hSpCas9	negative selection	6714282
114709619	114709642	1	-	27260156	HCC44	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.5434573222179944	[889]	[545,555,1102,630]	-7	hSpCas9	negative selection	6771274
114709596	114709619	1	+	27260156	HCC44	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.20163518993398982	[624]	[1052,678,946,635]	3	hSpCas9	negative selection	6771275
114708543	114708566	1	-	27260156	HCC44	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.1030368698081052	[549]	[898,469,768,597]	1	hSpCas9	negative selection	6771276
114713871	114713894	1	-	27260156	HCC44	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.5227943319051425	[544]	[388,530,473,311]	-7	hSpCas9	negative selection	6835531
114713861	114713884	1	+	27260156	HCC44	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.0515798159504679	[232]	[171,312,283,306]	0	hSpCas9	negative selection	6835532
114716067	114716090	1	+	27260156	HCC44	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	0.06514528740594247	[480]	[543,594,542,578]	1	hSpCas9	negative selection	6835533
114709619	114709642	1	-	27260156	G402	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.1108469810887529	[889]	[940,1162,769,1137]	-1	hSpCas9	negative selection	6892525
114709596	114709619	1	+	27260156	G402	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.37300267950678273	[624]	[1345,934,887,833]	4	hSpCas9	negative selection	6892526
114708543	114708566	1	-	27260156	G402	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.3053216872362071	[549]	[1137,755,985,490]	4	hSpCas9	negative selection	6892527
114713871	114713894	1	-	27260156	G402	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.11661114712823178	[544]	[1089,461,469,494]	-1	hSpCas9	negative selection	6956782
114713861	114713884	1	+	27260156	G402	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.4168064817428312	[232]	[182,302,153,211]	-5	hSpCas9	negative selection	6956783
114716067	114716090	1	+	27260156	G402	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.32010483983350324	[480]	[343,406,533,566]	-4	hSpCas9	negative selection	6956784
114709619	114709642	1	-	27260156	L33	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	0.1347973171466138	[889]	[862,434,621,996]	3	hSpCas9	negative selection	7013776
114709596	114709619	1	+	27260156	L33	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.044412662456370655	[624]	[706,248,349,703]	1	hSpCas9	negative selection	7013777
114708543	114708566	1	-	27260156	L33	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.25096262197445096	[549]	[689,217,363,813]	5	hSpCas9	negative selection	7013778
114713871	114713894	1	-	27260156	L33	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.19392229520857981	[544]	[548,204,252,451]	-4	hSpCas9	negative selection	7078033
114713861	114713884	1	+	27260156	L33	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.42919366622745003	[232]	[183,47,143,161]	-7	hSpCas9	negative selection	7078034
114716067	114716090	1	+	27260156	L33	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.3558739872570998	[480]	[343,158,285,317]	-7	hSpCas9	negative selection	7078035
114709619	114709642	1	-	27260156	K562	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.7529874945698234	[889]	[681,408,657,172]	-7	hSpCas9	negative selection	7135027
114709596	114709619	1	+	27260156	K562	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-0.06970841864221111	[624]	[635,340,853,305]	-1	hSpCas9	negative selection	7135028
114708543	114708566	1	-	27260156	K562	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.1134922037079594	[549]	[565,362,417,732]	1	hSpCas9	negative selection	7135029
114713871	114713894	1	-	27260156	K562	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.4728206068769598	[544]	[525,294,128,442]	-5	hSpCas9	negative selection	7199284
114713861	114713884	1	+	27260156	K562	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.2996116750323352	[232]	[222,360,219,219]	4	hSpCas9	negative selection	7199285
114716067	114716090	1	+	27260156	K562	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.18743027915846022	[480]	[419,450,471,184]	-2	hSpCas9	negative selection	7199286
114709619	114709642	1	-	27260156	HT29	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.3104654851953278	[889]	[1037,962,712,798]	-6	hSpCas9	negative selection	7256278
114709596	114709619	1	+	27260156	HT29	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.278467452160204	[624]	[856,1156,1040,670]	5	hSpCas9	negative selection	7256279
114708543	114708566	1	-	27260156	HT29	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.18468125163941704	[549]	[796,910,726,630]	3	hSpCas9	negative selection	7256280
114713871	114713894	1	-	27260156	HT29	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.4900233413501859	[544]	[613,482,278,513]	-7	hSpCas9	negative selection	7320535
114713861	114713884	1	+	27260156	HT29	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.034838883456424496	[232]	[190,425,366,190]	0	hSpCas9	negative selection	7320536
114716067	114716090	1	+	27260156	HT29	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.29754421417050186	[480]	[626,540,463,305]	-5	hSpCas9	negative selection	7320537
114709619	114709642	1	-	27260156	MHHES1	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.26229617326119115	[889]	[1128,610,842,768]	-5	hSpCas9	negative selection	7377529
114709596	114709619	1	+	27260156	MHHES1	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-0.0492824641171013	[624]	[824,770,608,555]	-1	hSpCas9	negative selection	7377530
114708543	114708566	1	-	27260156	MHHES1	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.02664355514644176	[549]	[423,785,774,537]	0	hSpCas9	negative selection	7377531
114713871	114713894	1	-	27260156	MHHES1	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.2874692417374301	[544]	[740,750,359,258]	-5	hSpCas9	negative selection	7441786
114713861	114713884	1	+	27260156	MHHES1	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.33379004967595427	[232]	[235,226,161,207]	-6	hSpCas9	negative selection	7441787
114716067	114716090	1	+	27260156	MHHES1	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.10337116713523907	[480]	[691,488,575,314]	-2	hSpCas9	negative selection	7441788
114709619	114709642	1	-	27260156	MEWO	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.27870529246649944	[889]	[854,614,621]	-6	hSpCas9	negative selection	7498780
114709596	114709619	1	+	27260156	MEWO	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.22173431357032442	[624]	[810,573,685]	5	hSpCas9	negative selection	7498781
114708543	114708566	1	-	27260156	MEWO	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	-0.01992793428490036	[549]	[584,384,567]	0	hSpCas9	negative selection	7498782
114713871	114713894	1	-	27260156	MEWO	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.4614985443585401	[544]	[384,296,431]	-7	hSpCas9	negative selection	7563037
114713861	114713884	1	+	27260156	MEWO	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.30999117719203695	[232]	[194,213,121]	-6	hSpCas9	negative selection	7563038
114716067	114716090	1	+	27260156	MEWO	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.4706528920779431	[480]	[334,352,287]	-7	hSpCas9	negative selection	7563039
114709619	114709642	1	-	27260156	LNCAPCLONEFGC	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.61169020157424	[889]	[425,490,638,574]	-7	hSpCas9	negative selection	7620031
114709596	114709619	1	+	27260156	LNCAPCLONEFGC	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.011410112487250212	[624]	[504,542,655,593]	0	hSpCas9	negative selection	7620032
114708543	114708566	1	-	27260156	LNCAPCLONEFGC	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.21364437597649213	[549]	[621,471,700,539]	3	hSpCas9	negative selection	7620033
114713871	114713894	1	-	27260156	LNCAPCLONEFGC	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.5468278977350438	[544]	[215,318,538,310]	-7	hSpCas9	negative selection	7684288
114713861	114713884	1	+	27260156	LNCAPCLONEFGC	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.5043756457064537	[232]	[161,147,115,163]	-6	hSpCas9	negative selection	7684289
114716067	114716090	1	+	27260156	LNCAPCLONEFGC	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.056537136626632414	[480]	[336,440,413,482]	-1	hSpCas9	negative selection	7684290
114709619	114709642	1	-	27260156	PANC0327	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.2543852803927188	[889]	[767,781,513,579]	-4	hSpCas9	negative selection	7741282
114709596	114709619	1	+	27260156	PANC0327	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.38654108272023074	[624]	[631,620,896,758]	6	hSpCas9	negative selection	7741283
114708543	114708566	1	-	27260156	PANC0327	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.2183203796201383	[549]	[534,481,685,578]	3	hSpCas9	negative selection	7741284
114713871	114713894	1	-	27260156	PANC0327	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.28370641744463465	[544]	[414,299,545,343]	-4	hSpCas9	negative selection	7805539
114713861	114713884	1	+	27260156	PANC0327	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.04557549760321877	[232]	[630,70,80,70]	0	hSpCas9	negative selection	7805540
114716067	114716090	1	+	27260156	PANC0327	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.03784309364662493	[480]	[319,406,430,499]	0	hSpCas9	negative selection	7805541
114709619	114709642	1	-	27260156	NCIH2009	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	0.22797328896860514	[889]	[1976,1315,1178]	3	hSpCas9	negative selection	7862533
114709596	114709619	1	+	27260156	NCIH2009	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.4131980097186054	[624]	[1396,928,1210]	5	hSpCas9	negative selection	7862534
114708543	114708566	1	-	27260156	NCIH2009	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.4100883027016622	[549]	[1138,1174,767]	5	hSpCas9	negative selection	7862535
114713871	114713894	1	-	27260156	NCIH2009	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.5347052520577597	[544]	[889,1335,1034]	7	hSpCas9	negative selection	7926790
114713861	114713884	1	+	27260156	NCIH2009	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.5652263208960109	[232]	[247,175,241]	-6	hSpCas9	negative selection	7926791
114716067	114716090	1	+	27260156	NCIH2009	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	0.24662299595652398	[480]	[1010,677,745]	3	hSpCas9	negative selection	7926792
114709619	114709642	1	-	27260156	NCIH1373	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.41207022001761284	[889]	[869,686,339,303]	-4	hSpCas9	negative selection	7983784
114709596	114709619	1	+	27260156	NCIH1373	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.032078795144837136	[624]	[794,443,943,187]	0	hSpCas9	negative selection	7983785
114708543	114708566	1	-	27260156	NCIH1373	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.25936907107042895	[549]	[620,419,1129,206]	2	hSpCas9	negative selection	7983786
114713871	114713894	1	-	27260156	NCIH1373	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.1078544144508001	[544]	[335,452,660,310]	1	hSpCas9	negative selection	8048041
114713861	114713884	1	+	27260156	NCIH1373	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.31179721299298024	[232]	[254,225,173,49]	-3	hSpCas9	negative selection	8048042
114716067	114716090	1	+	27260156	NCIH1373	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	0.30245592720873227	[480]	[324,421,1057,216]	3	hSpCas9	negative selection	8048043
114709619	114709642	1	-	27260156	PATU8902	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.016727964465683032	[889]	[1132,1924,802,1131]	0	hSpCas9	negative selection	8105035
114709596	114709619	1	+	27260156	PATU8902	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.1806960925474111	[624]	[539,777,926,1812]	1	hSpCas9	negative selection	8105036
114708543	114708566	1	-	27260156	PATU8902	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.828417819345591	[549]	[1147,1426,1031,1985]	8	hSpCas9	negative selection	8105037
114713871	114713894	1	-	27260156	PATU8902	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.13103051271931726	[544]	[879,470,672,751]	-1	hSpCas9	negative selection	8169292
114713861	114713884	1	+	27260156	PATU8902	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.005334227535008562	[232]	[405,313,313,248]	0	hSpCas9	negative selection	8169293
114716067	114716090	1	+	27260156	PATU8902	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.06423573543826325	[480]	[603,506,682,767]	0	hSpCas9	negative selection	8169294
114709619	114709642	1	-	27260156	PANC1	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.025963826077456176	[889]	[513,1105,741,712]	0	hSpCas9	negative selection	8226286
114709596	114709619	1	+	27260156	PANC1	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.004800980224205165	[624]	[497,584,535,536]	0	hSpCas9	negative selection	8226287
114708543	114708566	1	-	27260156	PANC1	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.36632504751012995	[549]	[765,652,616,425]	6	hSpCas9	negative selection	8226288
114713871	114713894	1	-	27260156	PANC1	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.17322651599082875	[544]	[620,424,709,353]	2	hSpCas9	negative selection	8290543
114713861	114713884	1	+	27260156	PANC1	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.04843951571353666	[232]	[209,259,165,199]	0	hSpCas9	negative selection	8290544
114716067	114716090	1	+	27260156	PANC1	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	0.14255527300327625	[480]	[419,522,617,297]	2	hSpCas9	negative selection	8290545
114709619	114709642	1	-	27260156	PANC0813	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.1571632162664579	[889]	[777,995,950,1004]	-3	hSpCas9	negative selection	8347537
114709596	114709619	1	+	27260156	PANC0813	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.15251695247205926	[624]	[821,807,1052,593]	2	hSpCas9	negative selection	8347538
114708543	114708566	1	-	27260156	PANC0813	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.06665318574821108	[549]	[671,707,721,606]	1	hSpCas9	negative selection	8347539
114713871	114713894	1	-	27260156	PANC0813	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.2875836253253915	[544]	[559,476,479,579]	-4	hSpCas9	negative selection	8411794
114713861	114713884	1	+	27260156	PANC0813	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.6584551006949788	[232]	[233,153,175,136]	-7	hSpCas9	negative selection	8411795
114716067	114716090	1	+	27260156	PANC0813	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.2162777448576455	[480]	[552,488,534,379]	-3	hSpCas9	negative selection	8411796
114709619	114709642	1	-	27260156	RDES	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.6538509900139213	[889]	[588,623,589,816]	-8	hSpCas9	negative selection	8468788
114709596	114709619	1	+	27260156	RDES	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-0.2710390760975716	[624]	[464,461,734,777]	-4	hSpCas9	negative selection	8468789
114708543	114708566	1	-	27260156	RDES	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.005808587578395058	[549]	[562,712,478,789]	0	hSpCas9	negative selection	8468790
114713871	114713894	1	-	27260156	RDES	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.6253498928265283	[544]	[354,395,444,433]	-8	hSpCas9	negative selection	8533045
114713861	114713884	1	+	27260156	RDES	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.3311435207986366	[232]	[177,164,219,309]	-5	hSpCas9	negative selection	8533046
114716067	114716090	1	+	27260156	RDES	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.21517368235624446	[480]	[375,444,552,557]	-4	hSpCas9	negative selection	8533047
114709619	114709642	1	-	27260156	PC3	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.5972164402528279	[889]	[467,475,980,560]	-8	hSpCas9	negative selection	8590039
114709596	114709619	1	+	27260156	PC3	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.18018348645287413	[624]	[470,641,972,882]	4	hSpCas9	negative selection	8590040
114708543	114708566	1	-	27260156	PC3	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.04360195406770842	[549]	[463,526,746,568]	1	hSpCas9	negative selection	8590041
114713871	114713894	1	-	27260156	PC3	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.6789270416908829	[544]	[175,342,579,397]	-9	hSpCas9	negative selection	8654296
114713861	114713884	1	+	27260156	PC3	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.04444760760076849	[232]	[227,193,316,221]	1	hSpCas9	negative selection	8654297
114716067	114716090	1	+	27260156	PC3	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.09197749938496041	[480]	[269,296,1074,447]	-2	hSpCas9	negative selection	8654298
114709619	114709642	1	-	27260156	PATU8988T	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.05588910951446213	[889]	[1112,570,763,838]	-1	hSpCas9	negative selection	8711290
114709596	114709619	1	+	27260156	PATU8988T	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.23759344864558435	[624]	[635,990,660,575]	4	hSpCas9	negative selection	8711291
114708543	114708566	1	-	27260156	PATU8988T	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.3568146636237598	[549]	[980,564,605,549]	6	hSpCas9	negative selection	8711292
114713871	114713894	1	-	27260156	PATU8988T	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.16443045782056567	[544]	[425,390,510,549]	-3	hSpCas9	negative selection	8775547
114713861	114713884	1	+	27260156	PATU8988T	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.15495829541776673	[232]	[237,240,246,277]	2	hSpCas9	negative selection	8775548
114716067	114716090	1	+	27260156	PATU8988T	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.4680698294566601	[480]	[483,361,232,262]	-6	hSpCas9	negative selection	8775549
114709619	114709642	1	-	27260156	T47D	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.21144620145142334	[889]	[836,923,1012,799]	-5	hSpCas9	negative selection	8832541
114709596	114709619	1	+	27260156	T47D	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.3123241099086866	[624]	[940,945,840,884]	6	hSpCas9	negative selection	8832542
114708543	114708566	1	-	27260156	T47D	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.35015058972893043	[549]	[877,856,694,835]	7	hSpCas9	negative selection	8832543
114713871	114713894	1	-	27260156	T47D	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.1573745504892376	[544]	[563,523,644,545]	-4	hSpCas9	negative selection	8896798
114713861	114713884	1	+	27260156	T47D	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.01371465221052881	[232]	[320,250,162,367]	0	hSpCas9	negative selection	8896799
114716067	114716090	1	+	27260156	T47D	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.08799711575555505	[480]	[531,414,674,492]	-2	hSpCas9	negative selection	8896800
114709619	114709642	1	-	27260156	SU8686	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.11399254338302833	[889]	[786,797,699,1002]	-2	hSpCas9	negative selection	8953792
114709596	114709619	1	+	27260156	SU8686	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-0.09499466455253097	[624]	[568,469,689,610]	-2	hSpCas9	negative selection	8953793
114708543	114708566	1	-	27260156	SU8686	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	-0.2615645708057037	[549]	[446,388,336,686]	-4	hSpCas9	negative selection	8953794
114713871	114713894	1	-	27260156	SU8686	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.3622021786334947	[544]	[414,374,496,395]	-6	hSpCas9	negative selection	9018049
114713861	114713884	1	+	27260156	SU8686	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.39356274517587075	[232]	[143,125,211,241]	-6	hSpCas9	negative selection	9018050
114716067	114716090	1	+	27260156	SU8686	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.20293916883196456	[480]	[393,333,409,550]	-4	hSpCas9	negative selection	9018051
114709619	114709642	1	-	27260156	SKES1	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.3961649479803856	[889]	[591,719,729,645]	-7	hSpCas9	negative selection	9075043
114709596	114709619	1	+	27260156	SKES1	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.26452273773125395	[624]	[819,761,791,637]	5	hSpCas9	negative selection	9075044
114708543	114708566	1	-	27260156	SKES1	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	-0.14840728440067974	[549]	[518,503,475,481]	-3	hSpCas9	negative selection	9075045
114713871	114713894	1	-	27260156	SKES1	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.5879650160691351	[544]	[441,435,299,293]	-8	hSpCas9	negative selection	9139300
114713861	114713884	1	+	27260156	SKES1	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.07658173641995236	[232]	[238,221,259,166]	-2	hSpCas9	negative selection	9139301
114716067	114716090	1	+	27260156	SKES1	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.24717323769647764	[480]	[367,343,582,313]	-5	hSpCas9	negative selection	9139302
114709619	114709642	1	-	27260156	TOV112D	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.2295900538302792	[889]	[688,805,718,828]	-4	hSpCas9	negative selection	9196294
114709596	114709619	1	+	27260156	TOV112D	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.42341587196986324	[624]	[1117,764,940,545]	7	hSpCas9	negative selection	9196295
114708543	114708566	1	-	27260156	TOV112D	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	-0.12505322662763102	[549]	[644,725,326,390]	-2	hSpCas9	negative selection	9196296
114713871	114713894	1	-	27260156	TOV112D	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.2721205398759408	[544]	[572,530,391,343]	-5	hSpCas9	negative selection	9260551
114713861	114713884	1	+	27260156	TOV112D	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	0.19038146593368976	[232]	[230,346,288,215]	3	hSpCas9	negative selection	9260552
114716067	114716090	1	+	27260156	TOV112D	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.3208009178206183	[480]	[355,408,416,363]	-6	hSpCas9	negative selection	9260553
114709619	114709642	1	-	27260156	TC71	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.2589978775571088	[889]	[730,802,950,693]	-6	hSpCas9	negative selection	9317545
114709596	114709619	1	+	27260156	TC71	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.0958809735681388	[624]	[688,730,659,790]	2	hSpCas9	negative selection	9317546
114708543	114708566	1	-	27260156	TC71	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	-0.01600695664399665	[549]	[542,623,573,592]	0	hSpCas9	negative selection	9317547
114713871	114713894	1	-	27260156	TC71	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.6579632905581554	[544]	[444,357,251,431]	-9	hSpCas9	negative selection	9381802
114713861	114713884	1	+	27260156	TC71	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.16799386956454687	[232]	[247,187,213,239]	-4	hSpCas9	negative selection	9381803
114716067	114716090	1	+	27260156	TC71	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	-0.32185615807242185	[480]	[337,486,409,416]	-7	hSpCas9	negative selection	9381804
114709619	114709642	1	-	27260156	TC32	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.5413989538512469	[889]	[524,395,755,700]	-8	hSpCas9	negative selection	9438796
114709596	114709619	1	+	27260156	TC32	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.0859710371481271	[624]	[611,489,737,690]	1	hSpCas9	negative selection	9438797
114708543	114708566	1	-	27260156	TC32	viability	TTGTATGGGATTGCCATGTGTGG	NRAS	ENSG00000213281	0.04843679723115016	[549]	[557,558,541,424]	0	hSpCas9	negative selection	9438798
114713871	114713894	1	-	27260156	TC32	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.42824673810944625	[544]	[376,299,408,452]	-7	hSpCas9	negative selection	9503053
114713861	114713884	1	+	27260156	TC32	viability	CTTCGCCTGTCCTCATGTATTGG	NRAS	ENSG00000213281	-0.09298387395843255	[232]	[234,74,381,193]	-2	hSpCas9	negative selection	9503054
114716067	114716090	1	+	27260156	TC32	viability	ATTCATCTACAAAGTGGTTCTGG	NRAS	ENSG00000213281	0.0034323082780904346	[480]	[340,373,563,576]	0	hSpCas9	negative selection	9503055
114708530	114708553	1	+	27869803	HPAFII	viability after 27 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.1510288383833629	[1347]	[697,860,NaN]	1	hSpCas9	negative selection	9528101
114708530	114708553	1	-	27869803	HPAFII	viability after 27 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.663384925709906	[677]	[509,609,NaN]	5	hSpCas9	negative selection	9528102
114708530	114708553	1	+	27869803	HPAFII	viability after 15 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	-0.15456659117476912	[1347]	[1451,1207,NaN]	-2	hSpCas9	negative selection	9610550
114708530	114708553	1	-	27869803	HPAFII	viability after 15 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.6136208035422757	[677]	[1421,923,NaN]	7	hSpCas9	negative selection	9610551
114708530	114708553	1	+	27869803	ASPC1	viability after 36 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.25582123397463974	[3097]	[1379,1486,1059]	2	hSpCas9	negative selection	9692999
114708530	114708553	1	-	27869803	ASPC1	viability after 36 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.5073233970888493	[1491]	[846,1050,410]	5	hSpCas9	negative selection	9693000
114708530	114708553	1	+	27869803	PATU8988S	viability after 35 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	-0.021738119547566992	[2664]	[959,1154,NaN]	0	hSpCas9	negative selection	9775448
114708530	114708553	1	-	27869803	PATU8988S	viability after 35 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.17240446607478122	[1245]	[357,773,NaN]	2	hSpCas9	negative selection	9775449
114708530	114708553	1	+	27869803	PATU8988S	viability after 31 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.21149788518936985	[2664]	[1002,1519,NaN]	2	hSpCas9	negative selection	9857897
114708530	114708553	1	-	27869803	PATU8988S	viability after 31 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	-0.16720211317418987	[1245]	[368,535,NaN]	-2	hSpCas9	negative selection	9857898
114708530	114708553	1	+	27869803	HPAFII	viability after 35 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.37709068039105365	[1347]	[604,1202,NaN]	2	hSpCas9	negative selection	9940346
114708530	114708553	1	-	27869803	HPAFII	viability after 35 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	1.092249578417768	[677]	[561,922,NaN]	7	hSpCas9	negative selection	9940347
114708530	114708553	1	+	27869803	HPAFII	viability after 31 days	CCTTGTTACATCACCACACATGG	NRAS	ENSG00000213281	0.14041049107561498	[1347]	[595,1092,NaN]	1	hSpCas9	negative selection	10022795
114708530	114708553	1	-	27869803	HPAFII	viability after 31 days	CCATGTGTGGTGATGTAACAAGG	NRAS	ENSG00000213281	0.9934134360721087	[677]	[523,1011,NaN]	7	hSpCas9	negative selection	10022796
114716139	114716162	1	-	28162770	P31FUJ	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	-2.186152111115557	[212]	[54]	-8	hSpCas9	negative selection	10202470
114713911	114713934	1	-	28162770	P31FUJ	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	-0.8137848542229895	[180]	[120]	-6	hSpCas9	negative selection	10202471
114716038	114716061	1	+	28162770	P31FUJ	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	-3.431071831550653	[513]	[55]	-9	hSpCas9	negative selection	10202472
114713786	114713809	1	+	28162770	P31FUJ	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	-1.36555741326615	[181]	[82]	-7	hSpCas9	negative selection	10202473
114716126	114716149	1	-	28162770	P31FUJ	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	-0.394553274410991	[65]	[58]	-4	hSpCas9	negative selection	10202474
114713860	114713883	1	-	28162770	P31FUJ	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	-0.7878632194216728	[190]	[129]	-6	hSpCas9	negative selection	10202475
114713871	114713894	1	-	28162770	P31FUJ	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-3.4870434917901663	[228]	[23]	-9	hSpCas9	negative selection	10202476
114709619	114709642	1	-	28162770	P31FUJ	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-1.2036558587548623	[48]	[24]	-7	hSpCas9	negative selection	10202477
114709596	114709619	1	+	28162770	P31FUJ	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-1.4642753483562374	[424]	[180]	-7	hSpCas9	negative selection	10202478
114716049	114716072	1	-	28162770	P31FUJ	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	-2.087709055952002	[292]	[80]	-8	hSpCas9	negative selection	10202479
114716139	114716162	1	-	28162770	TF1	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	NaN	[NaN]	[38]	1	hSpCas9	negative selection	10371836
114713911	114713934	1	-	28162770	TF1	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10371837
114716038	114716061	1	+	28162770	TF1	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10371838
114713786	114713809	1	+	28162770	TF1	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	NaN	[NaN]	[101]	1	hSpCas9	negative selection	10371839
114716126	114716149	1	-	28162770	TF1	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10371840
114713860	114713883	1	-	28162770	TF1	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10371841
114713871	114713894	1	-	28162770	TF1	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	NaN	[NaN]	[143]	1	hSpCas9	negative selection	10371842
114709619	114709642	1	-	28162770	TF1	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10371843
114709596	114709619	1	+	28162770	TF1	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	NaN	[NaN]	[171]	1	hSpCas9	negative selection	10371844
114716049	114716072	1	-	28162770	TF1	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10371845
114716139	114716162	1	-	28162770	SKM1	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	1.6914075416741166	[61]	[353]	9	hSpCas9	negative selection	10541202
114713911	114713934	1	-	28162770	SKM1	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	0.7409344963691518	[43]	[129]	7	hSpCas9	negative selection	10541203
114716038	114716061	1	+	28162770	SKM1	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	1.6315232796485697	[177]	[974]	9	hSpCas9	negative selection	10541204
114713786	114713809	1	+	28162770	SKM1	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	2.0439809540063067	[61]	[451]	9	hSpCas9	negative selection	10541205
114716126	114716149	1	-	28162770	SKM1	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	1.463400520840243	[15]	[77]	9	hSpCas9	negative selection	10541206
114713860	114713883	1	-	28162770	SKM1	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	1.2094765334511626	[67]	[277]	9	hSpCas9	negative selection	10541207
114713871	114713894	1	-	28162770	SKM1	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	1.9483158447110687	[61]	[422]	9	hSpCas9	negative selection	10541208
114709619	114709642	1	-	28162770	SKM1	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	0.5800967455493402	[13]	[36]	5	hSpCas9	negative selection	10541209
114709596	114709619	1	+	28162770	SKM1	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	1.5982001459615391	[121]	[652]	9	hSpCas9	negative selection	10541210
114716049	114716072	1	-	28162770	SKM1	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	1.7165678972146994	[78]	[458]	9	hSpCas9	negative selection	10541211
114716139	114716162	1	-	28162770	SKM1	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	1.6914075416741166	[61]	[353]	9	hSpCas9	negative selection	10710568
114713911	114713934	1	-	28162770	SKM1	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	0.7409344963691518	[43]	[129]	7	hSpCas9	negative selection	10710569
114716038	114716061	1	+	28162770	SKM1	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	1.6315232796485697	[177]	[974]	9	hSpCas9	negative selection	10710570
114713786	114713809	1	+	28162770	SKM1	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	2.0439809540063067	[61]	[451]	9	hSpCas9	negative selection	10710571
114716126	114716149	1	-	28162770	SKM1	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	1.463400520840243	[15]	[77]	9	hSpCas9	negative selection	10710572
114713860	114713883	1	-	28162770	SKM1	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	1.2094765334511626	[67]	[277]	9	hSpCas9	negative selection	10710573
114713871	114713894	1	-	28162770	SKM1	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	1.9483158447110687	[61]	[422]	9	hSpCas9	negative selection	10710574
114709619	114709642	1	-	28162770	SKM1	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	0.5800967455493402	[13]	[36]	5	hSpCas9	negative selection	10710575
114709596	114709619	1	+	28162770	SKM1	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	1.5982001459615391	[121]	[652]	9	hSpCas9	negative selection	10710576
114716049	114716072	1	-	28162770	SKM1	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	1.7165678972146994	[78]	[458]	9	hSpCas9	negative selection	10710577
114716139	114716162	1	-	28162770	PL21	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	0.582936776767956	[180]	[117]	5	hSpCas9	negative selection	10879934
114713911	114713934	1	-	28162770	PL21	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	0.07640424606707541	[145]	[66]	0	hSpCas9	negative selection	10879935
114716038	114716061	1	+	28162770	PL21	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	0.9860148091364727	[434]	[374]	8	hSpCas9	negative selection	10879936
114713786	114713809	1	+	28162770	PL21	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	0.9985057533196694	[206]	[179]	8	hSpCas9	negative selection	10879937
114716126	114716149	1	-	28162770	PL21	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	-0.04086848501447471	[51]	[21]	0	hSpCas9	negative selection	10879938
114713860	114713883	1	-	28162770	PL21	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	1.1512300140083735	[209]	[202]	8	hSpCas9	negative selection	10879939
114713871	114713894	1	-	28162770	PL21	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.38505733040710505	[233]	[132]	3	hSpCas9	negative selection	10879940
114709619	114709642	1	-	28162770	PL21	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	1.318784110987939	[34]	[37]	9	hSpCas9	negative selection	10879941
114709596	114709619	1	+	28162770	PL21	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	1.0530127418332267	[360]	[325]	8	hSpCas9	negative selection	10879942
114716049	114716072	1	-	28162770	PL21	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	1.2820508122759375	[290]	[307]	9	hSpCas9	negative selection	10879943
114716139	114716162	1	-	28162770	P31FUJ	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	-2.186152111115557	[212]	[54]	-8	hSpCas9	negative selection	11049300
114713911	114713934	1	-	28162770	P31FUJ	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	-0.8137848542229895	[180]	[120]	-6	hSpCas9	negative selection	11049301
114716038	114716061	1	+	28162770	P31FUJ	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	-3.431071831550653	[513]	[55]	-9	hSpCas9	negative selection	11049302
114713786	114713809	1	+	28162770	P31FUJ	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	-1.36555741326615	[181]	[82]	-7	hSpCas9	negative selection	11049303
114716126	114716149	1	-	28162770	P31FUJ	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	-0.394553274410991	[65]	[58]	-4	hSpCas9	negative selection	11049304
114713860	114713883	1	-	28162770	P31FUJ	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	-0.7878632194216728	[190]	[129]	-6	hSpCas9	negative selection	11049305
114713871	114713894	1	-	28162770	P31FUJ	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-3.4870434917901663	[228]	[23]	-9	hSpCas9	negative selection	11049306
114709619	114709642	1	-	28162770	P31FUJ	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-1.2036558587548623	[48]	[24]	-7	hSpCas9	negative selection	11049307
114709596	114709619	1	+	28162770	P31FUJ	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-1.4642753483562374	[424]	[180]	-7	hSpCas9	negative selection	11049308
114716049	114716072	1	-	28162770	P31FUJ	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	-2.087709055952002	[292]	[80]	-8	hSpCas9	negative selection	11049309
114716139	114716162	1	-	28162770	OCIAML5	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	1.4766347526187917	[84]	[426]	9	hSpCas9	negative selection	11218666
114713911	114713934	1	-	28162770	OCIAML5	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	1.3512170275247462	[113]	[524]	9	hSpCas9	negative selection	11218667
114716038	114716061	1	+	28162770	OCIAML5	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	0.41633529547204895	[312]	[753]	3	hSpCas9	negative selection	11218668
114713786	114713809	1	+	28162770	OCIAML5	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	1.5368117679479922	[79]	[418]	9	hSpCas9	negative selection	11218669
114716126	114716149	1	-	28162770	OCIAML5	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	0.12775554719837245	[35]	[70]	1	hSpCas9	negative selection	11218670
114713860	114713883	1	-	28162770	OCIAML5	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	1.3639703554326275	[64]	[301]	9	hSpCas9	negative selection	11218671
114713871	114713894	1	-	28162770	OCIAML5	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.9654841182994959	[140]	[496]	8	hSpCas9	negative selection	11218672
114709619	114709642	1	-	28162770	OCIAML5	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	1.794823679000361	[18]	[118]	9	hSpCas9	negative selection	11218673
114709596	114709619	1	+	28162770	OCIAML5	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.5078904032222	[306]	[787]	4	hSpCas9	negative selection	11218674
114716049	114716072	1	-	28162770	OCIAML5	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	0.4887776150168871	[196]	[498]	4	hSpCas9	negative selection	11218675
114716139	114716162	1	-	28162770	EOL1	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	-0.15307312555193925	[419]	[198]	-1	hSpCas9	negative selection	11388032
114713911	114713934	1	-	28162770	EOL1	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	-1.2172261895576288	[202]	[45]	-7	hSpCas9	negative selection	11388033
114716038	114716061	1	+	28162770	EOL1	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	-0.9152752035387154	[1055]	[294]	-6	hSpCas9	negative selection	11388034
114713786	114713809	1	+	28162770	EOL1	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	-0.511037105112395	[329]	[121]	-4	hSpCas9	negative selection	11388035
114716126	114716149	1	-	28162770	EOL1	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	-1.323379741873051	[113]	[23]	-7	hSpCas9	negative selection	11388036
114713860	114713883	1	-	28162770	EOL1	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	1.089937418630495	[353]	[396]	8	hSpCas9	negative selection	11388037
114713871	114713894	1	-	28162770	EOL1	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.3141999524294648	[257]	[168]	3	hSpCas9	negative selection	11388038
114709619	114709642	1	-	28162770	EOL1	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.542578238856763	[46]	[16]	-4	hSpCas9	negative selection	11388039
114709596	114709619	1	+	28162770	EOL1	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.26275864532683824	[510]	[322]	2	hSpCas9	negative selection	11388040
114716049	114716072	1	-	28162770	EOL1	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	-0.9296013619660107	[375]	[103]	-6	hSpCas9	negative selection	11388041
114716139	114716162	1	-	28162770	MOLM13	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	0.38314718130334335	[297]	[280]	3	hSpCas9	negative selection	11557398
114713911	114713934	1	-	28162770	MOLM13	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	0.2619147196420934	[232]	[201]	2	hSpCas9	negative selection	11557399
114716038	114716061	1	+	28162770	MOLM13	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	0.2412837626655111	[742]	[634]	1	hSpCas9	negative selection	11557400
114713786	114713809	1	+	28162770	MOLM13	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	1.878219878145895	[306]	[815]	9	hSpCas9	negative selection	11557401
114716126	114716149	1	-	28162770	MOLM13	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	0.6003396775682283	[103]	[113]	4	hSpCas9	negative selection	11557402
114713860	114713883	1	-	28162770	MOLM13	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	1.23056068990326	[266]	[452]	8	hSpCas9	negative selection	11557403
114713871	114713894	1	-	28162770	MOLM13	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	0.5732423816908075	[263]	[283]	4	hSpCas9	negative selection	11557404
114709619	114709642	1	-	28162770	MOLM13	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.8012972512708103	[93]	[38]	-4	hSpCas9	negative selection	11557405
114709596	114709619	1	+	28162770	MOLM13	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-0.11232740752592729	[606]	[405]	0	hSpCas9	negative selection	11557406
114716049	114716072	1	-	28162770	MOLM13	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	-0.0906614883457818	[432]	[293]	0	hSpCas9	negative selection	11557407
114716139	114716162	1	-	28162770	HEL	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	0.5162904967594178	[285]	[261]	4	hSpCas9	negative selection	11726764
114713911	114713934	1	-	28162770	HEL	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	1.0907536537254736	[172]	[235]	8	hSpCas9	negative selection	11726765
114716038	114716061	1	+	28162770	HEL	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	0.0554989905681349	[633]	[421]	0	hSpCas9	negative selection	11726766
114713786	114713809	1	+	28162770	HEL	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	1.3486536802076001	[262]	[428]	9	hSpCas9	negative selection	11726767
114716126	114716149	1	-	28162770	HEL	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	1.9183732746137845	[56]	[137]	9	hSpCas9	negative selection	11726768
114713860	114713883	1	-	28162770	HEL	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	-0.4744447073699819	[281]	[129]	-3	hSpCas9	negative selection	11726769
114713871	114713894	1	-	28162770	HEL	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.7155616525519672	[240]	[93]	-5	hSpCas9	negative selection	11726770
114709619	114709642	1	-	28162770	HEL	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-3.4103725044592053	[82]	[4]	-9	hSpCas9	negative selection	11726771
114709596	114709619	1	+	28162770	HEL	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.18502042463301183	[525]	[382]	1	hSpCas9	negative selection	11726772
114716049	114716072	1	-	28162770	HEL	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	0.7293265169964476	[290]	[308]	6	hSpCas9	negative selection	11726773
114716139	114716162	1	-	28162770	MV411	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	0.17617886761295337	[165]	[157]	1	hSpCas9	negative selection	11896130
114713911	114713934	1	-	28162770	MV411	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	0.19609067078255504	[142]	[137]	1	hSpCas9	negative selection	11896131
114716038	114716061	1	+	28162770	MV411	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	-0.08412230642864427	[525]	[417]	0	hSpCas9	negative selection	11896132
114713786	114713809	1	+	28162770	MV411	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	-0.45384906790561247	[212]	[130]	-3	hSpCas9	negative selection	11896133
114716126	114716149	1	-	28162770	MV411	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	-0.36923380966571884	[68]	[44]	-3	hSpCas9	negative selection	11896134
114713860	114713883	1	-	28162770	MV411	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	0.5515243329099504	[178]	[220]	5	hSpCas9	negative selection	11896135
114713871	114713894	1	-	28162770	MV411	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.4939265072809478	[218]	[130]	-4	hSpCas9	negative selection	11896136
114709619	114709642	1	-	28162770	MV411	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.18552185649333097	[26]	[19]	-1	hSpCas9	negative selection	11896137
114709596	114709619	1	+	28162770	MV411	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.5005988981297034	[390]	[465]	4	hSpCas9	negative selection	11896138
114716049	114716072	1	-	28162770	MV411	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	-0.16220668972584984	[266]	[200]	-1	hSpCas9	negative selection	11896139
114716139	114716162	1	-	28162770	MONOMAC1	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	0.3787071236322238	[156]	[233]	4	hSpCas9	negative selection	12065496
114713911	114713934	1	-	28162770	MONOMAC1	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	0.31044690098388533	[101]	[144]	3	hSpCas9	negative selection	12065497
114716038	114716061	1	+	28162770	MONOMAC1	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	-0.8019908229681758	[326]	[214]	-6	hSpCas9	negative selection	12065498
114713786	114713809	1	+	28162770	MONOMAC1	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	0.0964088716703343	[132]	[162]	1	hSpCas9	negative selection	12065499
114716126	114716149	1	-	28162770	MONOMAC1	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	0.6774322708565872	[41]	[76]	6	hSpCas9	negative selection	12065500
114713860	114713883	1	-	28162770	MONOMAC1	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	0.18998627604969348	[116]	[152]	2	hSpCas9	negative selection	12065501
114713871	114713894	1	-	28162770	MONOMAC1	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.039935885974825	[112]	[125]	0	hSpCas9	negative selection	12065502
114709619	114709642	1	-	28162770	MONOMAC1	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	0.10781773446886689	[16]	[20]	1	hSpCas9	negative selection	12065503
114709596	114709619	1	+	28162770	MONOMAC1	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.661376675440735	[229]	[416]	6	hSpCas9	negative selection	12065504
114716049	114716072	1	-	28162770	MONOMAC1	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	0.2068600946140896	[194]	[257]	2	hSpCas9	negative selection	12065505
114716139	114716162	1	-	28162770	OCIAML2	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	0.45828707669635615	[38]	[296]	4	hSpCas9	negative selection	12234862
114713911	114713934	1	-	28162770	OCIAML2	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	-0.1282376277950834	[27]	[141]	-1	hSpCas9	negative selection	12234863
114716038	114716061	1	+	28162770	OCIAML2	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	-0.5285498011713428	[107]	[414]	-4	hSpCas9	negative selection	12234864
114713786	114713809	1	+	28162770	OCIAML2	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	0.7500995468716425	[30]	[288]	7	hSpCas9	negative selection	12234865
114716126	114716149	1	-	28162770	OCIAML2	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	1.6992951762001511	[6]	[125]	9	hSpCas9	negative selection	12234866
114713860	114713883	1	-	28162770	OCIAML2	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	0.7086938742024006	[33]	[307]	7	hSpCas9	negative selection	12234867
114713871	114713894	1	-	28162770	OCIAML2	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-0.4609146704089494	[36]	[148]	-4	hSpCas9	negative selection	12234868
114709619	114709642	1	-	28162770	OCIAML2	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-2.470629825242161	[9]	[9]	-8	hSpCas9	negative selection	12234869
114709596	114709619	1	+	28162770	OCIAML2	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	0.568898538944476	[53]	[443]	5	hSpCas9	negative selection	12234870
114716049	114716072	1	-	28162770	OCIAML2	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	0.19233518748026818	[41]	[265]	1	hSpCas9	negative selection	12234871
114716139	114716162	1	-	28162770	OCIAML3	viability	AATGACTGAGTACAAACTGGTGG	NRAS	ENSG00000213281	-3.153435048938182	[55]	[18]	-9	hSpCas9	negative selection	12404228
114713911	114713934	1	-	28162770	OCIAML3	viability	TTGGACATACTGGATACAGCTGG	NRAS	ENSG00000213281	-0.36749911051548345	[49]	[116]	-3	hSpCas9	negative selection	12404229
114716038	114716061	1	+	28162770	OCIAML3	viability	ACTGGGCCTCACCTCTATGGTGG	NRAS	ENSG00000213281	-4.897788388501266	[157]	[15]	-9	hSpCas9	negative selection	12404230
114713786	114713809	1	+	28162770	OCIAML3	viability	AATGCTCCTAGTACCTGTAGAGG	NRAS	ENSG00000213281	-0.695887254343377	[43]	[81]	-5	hSpCas9	negative selection	12404231
114716126	114716149	1	-	28162770	OCIAML3	viability	AAACTGGTGGTGGTTGGAGCAGG	NRAS	ENSG00000213281	-2.178970141045319	[17]	[11]	-8	hSpCas9	negative selection	12404232
114713860	114713883	1	-	28162770	OCIAML3	viability	CAATACATGAGGACAGGCGAAGG	NRAS	ENSG00000213281	-0.786652718266559	[55]	[97]	-5	hSpCas9	negative selection	12404233
114713871	114713894	1	-	28162770	OCIAML3	viability	CCATGAGAGACCAATACATGAGG	NRAS	ENSG00000213281	-3.2879045125984834	[54]	[16]	-9	hSpCas9	negative selection	12404234
114709619	114709642	1	-	28162770	OCIAML3	viability	TACAAAACAAGCCCACGAACTGG	NRAS	ENSG00000213281	-0.3716152189877153	[5]	[13]	-3	hSpCas9	negative selection	12404235
114709596	114709619	1	+	28162770	OCIAML3	viability	GAATGGAATCCCGTAACTCTTGG	NRAS	ENSG00000213281	-1.1853679122434702	[112]	[149]	-7	hSpCas9	negative selection	12404236
114716049	114716072	1	-	28162770	OCIAML3	viability	TGAATATGATCCCACCATAGAGG	NRAS	ENSG00000213281	-3.886789389552009	[97]	[19]	-9	hSpCas9	negative selection	12404237