Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 23594
• Symbol: ORC6
• Description: origin recognition complex subunit 6

DataSource: http://genomecrispr.dkfz.de/#!/results/ORC6

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
46691017	46691040	16	-	26472758	Jiyoye	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.5325051492203148	[444]	[57]	-9	hSpCas9	negative selection	114071
46696045	46696068	16	+	26472758	Jiyoye	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-1.109502379648808	[391]	[136]	-6	hSpCas9	negative selection	114072
46696026	46696049	16	+	26472758	Jiyoye	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.3863737410267004	[181]	[104]	-3	hSpCas9	negative selection	114073
46696074	46696097	16	-	26472758	Jiyoye	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	-1.2490458023851045	[248]	[78]	-7	hSpCas9	negative selection	114074
46693145	46693168	16	-	26472758	Jiyoye	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-4.232552922646175	[348]	[13]	-9	hSpCas9	negative selection	114075
46696063	46696086	16	+	26472758	Jiyoye	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-1.94332186557826	[254]	[49]	-8	hSpCas9	negative selection	114076
46689749	46689772	16	+	26472758	Jiyoye	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-0.36334277237135926	[86]	[50]	-3	hSpCas9	negative selection	114077
46691099	46691122	16	+	26472758	Jiyoye	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-2.762749619936439	[62]	[6]	-9	hSpCas9	negative selection	114078
46689693	46689716	16	+	26472758	Jiyoye	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-0.4508056136216987	[28]	[15]	-3	hSpCas9	negative selection	114079
46690979	46691002	16	+	26472758	Jiyoye	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-3.1288775187343365	[57]	[4]	-9	hSpCas9	negative selection	114080
46691017	46691040	16	-	26472758	KBM7	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-3.020117000703795	[1302,1132]	[99,43]	-9	hSpCas9	negative selection	305189
46696045	46696068	16	+	26472758	KBM7	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-2.47623629947228	[1159,832]	[69,94]	-9	hSpCas9	negative selection	305190
46696026	46696049	16	+	26472758	KBM7	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.7806643401749722	[985,536]	[256,154]	-6	hSpCas9	negative selection	305191
46696074	46696097	16	-	26472758	KBM7	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	-1.4959937756612738	[989,725]	[141,140]	-8	hSpCas9	negative selection	305192
46693145	46693168	16	-	26472758	KBM7	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-4.8597191674813915	[1065,797]	[15,13]	-9	hSpCas9	negative selection	305193
46696063	46696086	16	+	26472758	KBM7	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-0.8414383604268907	[876,744]	[238,187]	-6	hSpCas9	negative selection	305194
46689749	46689772	16	+	26472758	KBM7	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-0.8938867792793854	[496,689]	[107,193]	-6	hSpCas9	negative selection	305195
46691099	46691122	16	+	26472758	KBM7	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-5.775473613625009	[739,512]	[8,1]	-9	hSpCas9	negative selection	305196
46689693	46689716	16	+	26472758	KBM7	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-2.2619697708803765	[394,213]	[17,38]	-8	hSpCas9	negative selection	305197
46690979	46691002	16	+	26472758	KBM7	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-3.1799476058855065	[299,238]	[15,11]	-9	hSpCas9	negative selection	305198
46691017	46691040	16	-	26472758	Raji	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.337926975019045	[609]	[27]	-9	hSpCas9	negative selection	496307
46696045	46696068	16	+	26472758	Raji	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-0.4639040284504802	[629]	[105]	-4	hSpCas9	negative selection	496308
46696026	46696049	16	+	26472758	Raji	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	0.32260646129120496	[316]	[91]	3	hSpCas9	negative selection	496309
46696074	46696097	16	-	26472758	Raji	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	0.3260238218489397	[329]	[95]	3	hSpCas9	negative selection	496310
46693145	46693168	16	-	26472758	Raji	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-3.136319392208261	[340]	[8]	-9	hSpCas9	negative selection	496311
46696063	46696086	16	+	26472758	Raji	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-0.18634766768311073	[455]	[92]	-1	hSpCas9	negative selection	496312
46689749	46689772	16	+	26472758	Raji	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-1.2420252959358697	[264]	[25]	-7	hSpCas9	negative selection	496313
46691099	46691122	16	+	26472758	Raji	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-2.9016052478536554	[321]	[9]	-9	hSpCas9	negative selection	496314
46689693	46689716	16	+	26472758	Raji	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-3.8233538021892874	[182]	[2]	-9	hSpCas9	negative selection	496315
46690979	46691002	16	+	26472758	Raji	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-0.27508610144881374	[72]	[13]	-2	hSpCas9	negative selection	496316
46691017	46691040	16	-	26472758	K562	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.284360937661585	[830]	[143]	-8	hSpCas9	negative selection	687425
46696045	46696068	16	+	26472758	K562	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-0.9321393661083126	[980]	[433]	-5	hSpCas9	negative selection	687426
46696026	46696049	16	+	26472758	K562	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.22257085124711873	[621]	[449]	-1	hSpCas9	negative selection	687427
46696074	46696097	16	-	26472758	K562	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	-0.44953928741226834	[693]	[428]	-3	hSpCas9	negative selection	687428
46693145	46693168	16	-	26472758	K562	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-2.0236866677147693	[1025]	[212]	-7	hSpCas9	negative selection	687429
46696063	46696086	16	+	26472758	K562	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-0.6091592111518029	[776]	[429]	-4	hSpCas9	negative selection	687430
46689749	46689772	16	+	26472758	K562	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-0.5810484897756969	[520]	[293]	-4	hSpCas9	negative selection	687431
46691099	46691122	16	+	26472758	K562	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-4.399437462108278	[399]	[15]	-9	hSpCas9	negative selection	687432
46689693	46689716	16	+	26472758	K562	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-0.3757332015170095	[248]	[161]	-2	hSpCas9	negative selection	687433
46690979	46691002	16	+	26472758	K562	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-7.348038309601632	[192]	[0]	-9	hSpCas9	negative selection	687434
46689687	46689710	16	+	26627737	DLD1	viability	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-0.7392940379143532	[525]	[98,135,66]	-6	hSpCas9	negative selection	794176
46689747	46689770	16	-	26627737	DLD1	viability	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.7163258469365879	[977]	[46,162,74]	-8	hSpCas9	negative selection	794177
46691036	46691059	16	-	26627737	DLD1	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.6019643440364826	[831]	[83,80,90]	-8	hSpCas9	negative selection	794178
46691108	46691131	16	-	26627737	DLD1	viability	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-4.440156904317417	[577]	[2,0,18]	-9	hSpCas9	negative selection	794179
46696026	46696049	16	+	26627737	DLD1	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	0.8080179458296562	[541]	[227,460,219]	7	hSpCas9	negative selection	794180
46697549	46697572	16	+	26627737	DLD1	viability	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	1.3708248179613745	[311]	[210,413,153]	9	hSpCas9	negative selection	794181
46689687	46689710	16	+	26627737	GBM cells	viability after 5 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-0.09432875893900572	[425]	[212,214]	-1	hSpCas9	negative selection	876491
46689747	46689770	16	-	26627737	GBM cells	viability after 5 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.051045442614719	[254]	[87,43]	-9	hSpCas9	negative selection	876492
46691036	46691059	16	-	26627737	GBM cells	viability after 5 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.467625106701968	[311]	[55,64]	-9	hSpCas9	negative selection	876493
46691108	46691131	16	-	26627737	GBM cells	viability after 5 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-3.2225496375999816	[321]	[13,22]	-9	hSpCas9	negative selection	876494
46696026	46696049	16	+	26627737	GBM cells	viability after 5 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.5302909563197521	[306]	[99,127]	-7	hSpCas9	negative selection	876495
46697549	46697572	16	+	26627737	GBM cells	viability after 5 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.5671667189678775	[257]	[235,173]	7	hSpCas9	negative selection	876496
46689687	46689710	16	+	26627737	GBM cells	viability after 13 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	0.3370727391359648	[425]	[377,221]	4	hSpCas9	negative selection	958806
46689747	46689770	16	-	26627737	GBM cells	viability after 13 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.2480641686261305	[254]	[76,42]	-8	hSpCas9	negative selection	958807
46691036	46691059	16	-	26627737	GBM cells	viability after 13 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.2140559166417093	[311]	[83,63]	-8	hSpCas9	negative selection	958808
46691108	46691131	16	-	26627737	GBM cells	viability after 13 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-3.232495847609406	[321]	[22,14]	-9	hSpCas9	negative selection	958809
46696026	46696049	16	+	26627737	GBM cells	viability after 13 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.6598983861831518	[306]	[132,82]	-7	hSpCas9	negative selection	958810
46697549	46697572	16	+	26627737	GBM cells	viability after 13 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.7643558620344022	[257]	[282,200]	8	hSpCas9	negative selection	958811
46689687	46689710	16	+	26627737	GBM cells	viability after 21 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	0.4517373034232085	[425]	[350,284]	4	hSpCas9	negative selection	1041121
46689747	46689770	16	-	26627737	GBM cells	viability after 21 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.025950265818999	[254]	[78,57]	-7	hSpCas9	negative selection	1041122
46691036	46691059	16	-	26627737	GBM cells	viability after 21 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.4807522710530576	[311]	[66,54]	-8	hSpCas9	negative selection	1041123
46691108	46691131	16	-	26627737	GBM cells	viability after 21 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-3.4043477427762148	[321]	[15,16]	-9	hSpCas9	negative selection	1041124
46696026	46696049	16	+	26627737	GBM cells	viability after 21 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-1.895719273471234	[306]	[48,40]	-8	hSpCas9	negative selection	1041125
46697549	46697572	16	+	26627737	GBM cells	viability after 21 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.32625010359193757	[257]	[181,169]	3	hSpCas9	negative selection	1041126
46689687	46689710	16	+	26627737	RPE1	viability after 9 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-0.8009630151039457	[1301]	[181,300]	-5	hSpCas9	negative selection	1123436
46689747	46689770	16	-	26627737	RPE1	viability after 9 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.9871952335686238	[858]	[107,15]	-8	hSpCas9	negative selection	1123437
46691036	46691059	16	-	26627737	RPE1	viability after 9 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-3.566487259273656	[2083]	[58,49]	-9	hSpCas9	negative selection	1123438
46691108	46691131	16	-	26627737	RPE1	viability after 9 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-8.168110601833169	[1953]	[2,0]	-9	hSpCas9	negative selection	1123439
46696026	46696049	16	+	26627737	RPE1	viability after 9 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-2.780679373570267	[570]	[32,16]	-9	hSpCas9	negative selection	1123440
46697549	46697572	16	+	26627737	RPE1	viability after 9 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.5277488444588445	[1274]	[495,677]	3	hSpCas9	negative selection	1123441
46689687	46689710	16	+	26627737	RPE1	viability after 12 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-0.8637233481823199	[1301]	[233,147]	-5	hSpCas9	negative selection	1205751
46689747	46689770	16	-	26627737	RPE1	viability after 12 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-3.4193530921978508	[858]	[40,0]	-9	hSpCas9	negative selection	1205752
46691036	46691059	16	-	26627737	RPE1	viability after 12 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-3.7191523564423052	[2083]	[76,5]	-9	hSpCas9	negative selection	1205753
46691108	46691131	16	-	26627737	RPE1	viability after 12 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-9.036103340295249	[1953]	[0,0]	-9	hSpCas9	negative selection	1205754
46696026	46696049	16	+	26627737	RPE1	viability after 12 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-2.5078754912728303	[570]	[42,9]	-9	hSpCas9	negative selection	1205755
46697549	46697572	16	+	26627737	RPE1	viability after 12 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.6666106137668988	[1274]	[432,660]	4	hSpCas9	negative selection	1205756
46689687	46689710	16	+	26627737	RPE1	viability after 15 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-1.1835051680983177	[1301]	[96,224]	-6	hSpCas9	negative selection	1288066
46689747	46689770	16	-	26627737	RPE1	viability after 15 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-4.944483681881074	[858]	[13,1]	-9	hSpCas9	negative selection	1288067
46691036	46691059	16	-	26627737	RPE1	viability after 15 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-3.5993113120893474	[2083]	[96,1]	-9	hSpCas9	negative selection	1288068
46691108	46691131	16	-	26627737	RPE1	viability after 15 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-6.181120431660276	[1953]	[0,13]	-9	hSpCas9	negative selection	1288069
46696026	46696049	16	+	26627737	RPE1	viability after 15 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-2.9319786827542336	[570]	[39,2]	-9	hSpCas9	negative selection	1288070
46697549	46697572	16	+	26627737	RPE1	viability after 15 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.27677007094095873	[1274]	[411,460]	1	hSpCas9	negative selection	1288071
46689687	46689710	16	+	26627737	RPE1	viability after 18 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-0.5515226371018643	[1301]	[202,278]	-3	hSpCas9	negative selection	1370381
46689747	46689770	16	-	26627737	RPE1	viability after 18 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-7.256017154857544	[858]	[1,0]	-9	hSpCas9	negative selection	1370382
46691036	46691059	16	-	26627737	RPE1	viability after 18 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-3.6245993517221478	[2083]	[62,26]	-9	hSpCas9	negative selection	1370383
46691108	46691131	16	-	26627737	RPE1	viability after 18 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-9.042546491867643	[1953]	[0,0]	-9	hSpCas9	negative selection	1370384
46696026	46696049	16	+	26627737	RPE1	viability after 18 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-3.8434825290356884	[570]	[2,18]	-9	hSpCas9	negative selection	1370385
46697549	46697572	16	+	26627737	RPE1	viability after 18 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.2898120601112908	[1274]	[511,322]	1	hSpCas9	negative selection	1370386
46689687	46689710	16	+	26627737	HeLa	viability after 8 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	0.19193134467536677	[570]	[363,293,215]	1	hSpCas9	negative selection	1452696
46689747	46689770	16	-	26627737	HeLa	viability after 8 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.7286213417078091	[759]	[134,129,45]	-9	hSpCas9	negative selection	1452697
46691036	46691059	16	-	26627737	HeLa	viability after 8 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.2785155101460448	[267]	[177,84,46]	-3	hSpCas9	negative selection	1452698
46691108	46691131	16	-	26627737	HeLa	viability after 8 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-0.7902368938480105	[312]	[1,221,0]	-7	hSpCas9	negative selection	1452699
46696026	46696049	16	+	26627737	HeLa	viability after 8 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.1990624683193264	[530]	[216,243,149]	-2	hSpCas9	negative selection	1452700
46697549	46697572	16	+	26627737	HeLa	viability after 8 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.9206146358868691	[263]	[366,170,151]	7	hSpCas9	negative selection	1452701
46689687	46689710	16	+	26627737	HeLa	viability after 12 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-0.11147776901985368	[570]	[336,196,126]	-1	hSpCas9	negative selection	1535011
46689747	46689770	16	-	26627737	HeLa	viability after 12 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.1193020829546867	[759]	[194,136,103]	-8	hSpCas9	negative selection	1535012
46691036	46691059	16	-	26627737	HeLa	viability after 12 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.5189340260751951	[267]	[48,58,124]	-4	hSpCas9	negative selection	1535013
46691108	46691131	16	-	26627737	HeLa	viability after 12 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-2.9823799254041377	[312]	[0,31,13]	-9	hSpCas9	negative selection	1535014
46696026	46696049	16	+	26627737	HeLa	viability after 12 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.11737293291069911	[530]	[313,146,154]	-1	hSpCas9	negative selection	1535015
46697549	46697572	16	+	26627737	HeLa	viability after 12 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	1.1304763159240017	[263]	[453,123,156]	7	hSpCas9	negative selection	1535016
46689687	46689710	16	+	26627737	HeLa	viability after 15 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-0.2036249741315858	[570]	[240,162,200]	-2	hSpCas9	negative selection	1617326
46689747	46689770	16	-	26627737	HeLa	viability after 15 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.2428059932782962	[759]	[256,33,96]	-8	hSpCas9	negative selection	1617327
46691036	46691059	16	-	26627737	HeLa	viability after 15 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.04678197686136387	[267]	[46,87,188]	0	hSpCas9	negative selection	1617328
46691108	46691131	16	-	26627737	HeLa	viability after 15 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-1.033140511729925	[312]	[0,70,119]	-7	hSpCas9	negative selection	1617329
46696026	46696049	16	+	26627737	HeLa	viability after 15 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.046443198076638714	[530]	[304,229,81]	0	hSpCas9	negative selection	1617330
46697549	46697572	16	+	26627737	HeLa	viability after 15 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.6416752252455084	[263]	[185,206,104]	5	hSpCas9	negative selection	1617331
46689687	46689710	16	+	26627737	HeLa	viability after 18 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-0.14063778979050984	[570]	[175,138,200]	-1	hSpCas9	negative selection	1699641
46689747	46689770	16	-	26627737	HeLa	viability after 18 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.3843253675916705	[759]	[147,28,96]	-8	hSpCas9	negative selection	1699642
46691036	46691059	16	-	26627737	HeLa	viability after 18 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.05684785667566916	[267]	[29,72,188]	0	hSpCas9	negative selection	1699643
46691108	46691131	16	-	26627737	HeLa	viability after 18 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-1.0083730402022821	[312]	[0,60,119]	-7	hSpCas9	negative selection	1699644
46696026	46696049	16	+	26627737	HeLa	viability after 18 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.08377856362473529	[530]	[188,196,81]	0	hSpCas9	negative selection	1699645
46697549	46697572	16	+	26627737	HeLa	viability after 18 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.6224342191239622	[263]	[123,166,104]	5	hSpCas9	negative selection	1699646
46689687	46689710	16	+	26627737	HCT116	viability after 6 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	1.0101538469203073	[1036]	[765,86]	5	hSpCas9	negative selection	1781956
46689747	46689770	16	-	26627737	HCT116	viability after 6 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	0.9177576752938441	[773]	[332,172]	5	hSpCas9	negative selection	1781957
46691036	46691059	16	-	26627737	HCT116	viability after 6 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.1195578821359182	[979]	[106,50]	-6	hSpCas9	negative selection	1781958
46691108	46691131	16	-	26627737	HCT116	viability after 6 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	1.7926250485588693	[476]	[719,5]	8	hSpCas9	negative selection	1781959
46696026	46696049	16	+	26627737	HCT116	viability after 6 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	1.6886790363519106	[468]	[305,199]	8	hSpCas9	negative selection	1781960
46697549	46697572	16	+	26627737	HCT116	viability after 6 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	-0.19661086299850997	[614]	[162,40]	-1	hSpCas9	negative selection	1781961
46689687	46689710	16	+	26627737	HCT116	viability after 8 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-0.5169790524564627	[713]	[248,269,304]	-6	hSpCas9	negative selection	1864271
46689747	46689770	16	-	26627737	HCT116	viability after 8 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.1797615329528977	[533]	[123,171,93]	-8	hSpCas9	negative selection	1864272
46691036	46691059	16	-	26627737	HCT116	viability after 8 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.5072129478419978	[444]	[91,89,76]	-9	hSpCas9	negative selection	1864273
46691108	46691131	16	-	26627737	HCT116	viability after 8 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-0.6050058521384065	[238]	[49,113,94]	-6	hSpCas9	negative selection	1864274
46696026	46696049	16	+	26627737	HCT116	viability after 8 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.6093664450566912	[341]	[134,129,105]	-6	hSpCas9	negative selection	1864275
46697549	46697572	16	+	26627737	HCT116	viability after 8 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	-0.06665717483221334	[270]	[240,85,102]	0	hSpCas9	negative selection	1864276
46689687	46689710	16	+	26627737	HCT116	viability after 9 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	0.5617612071544831	[1036]	[377,432]	4	hSpCas9	negative selection	1946586
46689747	46689770	16	-	26627737	HCT116	viability after 9 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-0.46672019001939824	[773]	[129,164]	-3	hSpCas9	negative selection	1946587
46691036	46691059	16	-	26627737	HCT116	viability after 9 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.05767287569496	[979]	[261,17]	-6	hSpCas9	negative selection	1946588
46691108	46691131	16	-	26627737	HCT116	viability after 9 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-0.08672342140253536	[476]	[234,28]	0	hSpCas9	negative selection	1946589
46696026	46696049	16	+	26627737	HCT116	viability after 9 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	0.4482576531136408	[468]	[257,101]	3	hSpCas9	negative selection	1946590
46697549	46697572	16	+	26627737	HCT116	viability after 9 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	-0.30739884530002803	[614]	[249,39]	-2	hSpCas9	negative selection	1946591
46689687	46689710	16	+	26627737	HCT116	viability after 12 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-0.8542983883926178	[713]	[111,246,272]	-7	hSpCas9	negative selection	2028901
46689747	46689770	16	-	26627737	HCT116	viability after 12 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.887611973097663	[533]	[154,10,52]	-9	hSpCas9	negative selection	2028902
46691036	46691059	16	-	26627737	HCT116	viability after 12 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.3520051344540707	[444]	[58,144,74]	-8	hSpCas9	negative selection	2028903
46691108	46691131	16	-	26627737	HCT116	viability after 12 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-1.5584659278769808	[238]	[39,35,51]	-9	hSpCas9	negative selection	2028904
46696026	46696049	16	+	26627737	HCT116	viability after 12 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.706232354591523	[341]	[62,166,105]	-6	hSpCas9	negative selection	2028905
46697549	46697572	16	+	26627737	HCT116	viability after 12 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.11177992913956568	[270]	[177,130,149]	1	hSpCas9	negative selection	2028906
46689687	46689710	16	+	26627737	HCT116	viability after 15 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-0.6491188582073075	[713]	[231,217,329]	-6	hSpCas9	negative selection	2111216
46689747	46689770	16	-	26627737	HCT116	viability after 15 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-2.2610357171520103	[533]	[157,32,12]	-9	hSpCas9	negative selection	2111217
46691036	46691059	16	-	26627737	HCT116	viability after 15 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.4503183798119939	[444]	[59,82,132]	-8	hSpCas9	negative selection	2111218
46691108	46691131	16	-	26627737	HCT116	viability after 15 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-3.454316390111039	[238]	[0,8,25]	-9	hSpCas9	negative selection	2111219
46696026	46696049	16	+	26627737	HCT116	viability after 15 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.31037800476379085	[341]	[178,83,213]	-3	hSpCas9	negative selection	2111220
46697549	46697572	16	+	26627737	HCT116	viability after 15 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.17764171476734467	[270]	[148,133,240]	1	hSpCas9	negative selection	2111221
46689687	46689710	16	+	26627737	HCT116	viability after 18 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-1.1104885504784483	[713]	[157,122,202]	-7	hSpCas9	negative selection	2193531
46689747	46689770	16	-	26627737	HCT116	viability after 18 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.1575009840894483	[533]	[199,39,111]	-8	hSpCas9	negative selection	2193532
46691036	46691059	16	-	26627737	HCT116	viability after 18 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-2.2711002041956423	[444]	[10,72,47]	-9	hSpCas9	negative selection	2193533
46691108	46691131	16	-	26627737	HCT116	viability after 18 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-2.5442389250781865	[238]	[21,13,23]	-9	hSpCas9	negative selection	2193534
46696026	46696049	16	+	26627737	HCT116	viability after 18 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.48085532021962824	[341]	[112,72,174]	-4	hSpCas9	negative selection	2193535
46697549	46697572	16	+	26627737	HCT116	viability after 18 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.34940461834205183	[270]	[162,174,161]	3	hSpCas9	negative selection	2193536
46689741	46689764	16	-	24336569	HL60	viability	TGTCGGGCTCGGCGAGGCCCAGG	ORC6	ENSG00000091651	0.9852363005786212	[316]	[1327]	7	hSpCas9	negative selection	2282232
46689747	46689770	16	-	24336569	HL60	viability	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.739917666616579	[744]	[471]	-9	hSpCas9	negative selection	2282233
46689752	46689775	16	-	24336569	HL60	viability	TCACCTCAGCATGTCGGGCTCGG	ORC6	ENSG00000091651	-1.252875344132073	[606]	[538]	-8	hSpCas9	negative selection	2282234
46689757	46689780	16	-	24336569	HL60	viability	CGAACTCACCTCAGCATGTCGGG	ORC6	ENSG00000091651	-0.10424396928518886	[765]	[1507]	-1	hSpCas9	negative selection	2282235
46690987	46691010	16	-	24336569	HL60	viability	CAAGTACTCCTCTGCTTTCCTGG	ORC6	ENSG00000091651	-0.35526493733176034	[537]	[889]	-3	hSpCas9	negative selection	2282236
46690999	46691022	16	+	24336569	HL60	viability	AGGAGTACTTGCGCCTGTCCCGG	ORC6	ENSG00000091651	-3.077094501001132	[988]	[247]	-9	hSpCas9	negative selection	2282237
46691012	46691035	16	-	24336569	HL60	viability	CGACACACTTCACCCGGGACAGG	ORC6	ENSG00000091651	0.24554689455169204	[339]	[852]	2	hSpCas9	negative selection	2282238
46691017	46691040	16	-	24336569	HL60	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-7.753889442600393	[101]	[0]	-9	hSpCas9	negative selection	2282239
46691033	46691056	16	+	24336569	HL60	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-3.6712760010114485	[595]	[98]	-9	hSpCas9	negative selection	2282240
46691041	46691064	16	-	24336569	HL60	viability	GCTGGTCTCCGTGGTGCGTGCGG	ORC6	ENSG00000091651	-1.7009499921163829	[1162]	[756]	-9	hSpCas9	negative selection	2282241
46689741	46689764	16	-	24336569	KBM7	viability	TGTCGGGCTCGGCGAGGCCCAGG	ORC6	ENSG00000091651	-0.9758273062757172	[529]	[734]	-6	hSpCas9	negative selection	2349409
46689747	46689770	16	-	24336569	KBM7	viability	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-5.25221973390945	[530]	[37]	-9	hSpCas9	negative selection	2349410
46689752	46689775	16	-	24336569	KBM7	viability	TCACCTCAGCATGTCGGGCTCGG	ORC6	ENSG00000091651	-3.1556899280429036	[329]	[100]	-9	hSpCas9	negative selection	2349411
46689757	46689780	16	-	24336569	KBM7	viability	CGAACTCACCTCAGCATGTCGGG	ORC6	ENSG00000091651	0.10981504416346899	[633]	[1865]	1	hSpCas9	negative selection	2349412
46690987	46691010	16	-	24336569	KBM7	viability	CAAGTACTCCTCTGCTTTCCTGG	ORC6	ENSG00000091651	0.647707004000674	[475]	[2033]	6	hSpCas9	negative selection	2349413
46690999	46691022	16	+	24336569	KBM7	viability	AGGAGTACTTGCGCCTGTCCCGG	ORC6	ENSG00000091651	-3.877893882569425	[980]	[181]	-9	hSpCas9	negative selection	2349414
46691012	46691035	16	-	24336569	KBM7	viability	CGACACACTTCACCCGGGACAGG	ORC6	ENSG00000091651	-1.6189476148608637	[499]	[443]	-8	hSpCas9	negative selection	2349415
46691017	46691040	16	-	24336569	KBM7	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-9.366442433823476	[241]	[0]	-9	hSpCas9	negative selection	2349416
46691033	46691056	16	+	24336569	KBM7	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-2.809241635110392	[680]	[264]	-9	hSpCas9	negative selection	2349417
46691041	46691064	16	-	24336569	KBM7	viability	GCTGGTCTCCGTGGTGCGTGCGG	ORC6	ENSG00000091651	-3.7413643270905403	[862]	[175]	-9	hSpCas9	negative selection	2349418
46692750	46692773	16	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTCGGGAGGCTGTGG	ORC6	ENSG00000091651	-0.4892893999709095	[44,388]	[14,54]	-2	dCas9-VP64	positive selection	2465903
46692750	46692773	16	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTCGGGAGGCTGTGG	ORC6	ENSG00000091651	-0.16148281958930955	[134,276]	[52,65]	-1	dCas9-VP64	positive selection	2561158
46691108	46691131	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-0.11673776185182172	[2,2]	[2,0]	-2	hSpCas9	positive selection	3008942
46691034	46691057	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.3475961832921548	[3,3]	[3,0]	-5	hSpCas9	positive selection	3008943
46691100	46691123	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-0.31925076945351716	[1,1]	[0,1]	-4	hSpCas9	positive selection	3008944
46689747	46689770	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	0.0858619982827082	[2,2]	[2,2]	1	hSpCas9	positive selection	3008945
46691108	46691131	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	0.30233743547111375	[2,2]	[2,1]	5	hSpCas9	positive selection	3076800
46691034	46691057	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	0.3725547590404278	[3,3]	[3,3]	6	hSpCas9	positive selection	3076801
46691100	46691123	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	0.3846464081672346	[1,1]	[0,1]	6	hSpCas9	positive selection	3076802
46689747	46689770	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-0.8122190188973173	[2,2]	[1,0]	-9	hSpCas9	positive selection	3076803
46691033	46691056		+	24336571	A375	resistance to PLX after 7 days	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	0.04502226467833759	[3,2]	[2,3]	1	hSpCas9	positive selection	3133298
46692504	46692527		+	24336571	A375	resistance to PLX after 7 days	CTGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	0.16482706675560688	[4,3]	[5,4]	5	hSpCas9	positive selection	3133299
46692486	46692509		-	24336571	A375	resistance to PLX after 7 days	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	0.7847127135090397	[2,2]	[5,4]	9	hSpCas9	positive selection	3133300
46691036	46691059		-	24336571	A375	resistance to PLX after 7 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	0.058606245939306856	[3,3]	[3,3]	2	hSpCas9	positive selection	3133301
46691033	46691056		+	24336571	A375	resistance to PLX after 14 days	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	0.920929224797455	[3,2]	[2,2]	7	hSpCas9	positive selection	3191091
46692504	46692527		+	24336571	A375	resistance to PLX after 14 days	CTGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	0.8529501662280254	[3,1]	[2,1]	7	hSpCas9	positive selection	3191092
46692486	46692509		-	24336571	A375	resistance to PLX after 14 days	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	0.7026606731826261	[2,2]	[1,1]	6	hSpCas9	positive selection	3191093
46691036	46691059		-	24336571	A375	resistance to PLX after 14 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	0.055993156278861145	[3,3]	[1,1]	0	hSpCas9	positive selection	3191094
46691033	46691056		+	24336571	A375	viability after 7 days	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.6848849016983205	[5]	[3,2]	-7	hSpCas9	negative selection	3248884
46692504	46692527		+	24336571	A375	viability after 7 days	CTGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-0.6654193922460909	[7]	[4,3]	-7	hSpCas9	negative selection	3248885
46692486	46692509		-	24336571	A375	viability after 7 days	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.2972516108267054	[8]	[2,2]	-9	hSpCas9	negative selection	3248886
46691036	46691059		-	24336571	A375	viability after 7 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.365896374077327	[10]	[3,3]	-9	hSpCas9	negative selection	3248887
46691033	46691056		+	24336571	A375	viability after 14 days	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.6247092157486822	[5]	[3,2]	-6	hSpCas9	negative selection	3306677
46692504	46692527		+	24336571	A375	viability after 14 days	CTGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-1.17859479843127	[7]	[3,1]	-9	hSpCas9	negative selection	3306678
46692486	46692509		-	24336571	A375	viability after 14 days	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.3446745129852316	[8]	[2,2]	-9	hSpCas9	negative selection	3306679
46691036	46691059		-	24336571	A375	viability after 14 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.244424704974118	[10]	[3,3]	-9	hSpCas9	negative selection	3306680
46692486	46692509	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	1.0285075209499543	[74,74]	[0,0]	5	hSpCas9	positive selection	3384145
46693111	46693134	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	-1.037294537445792	[313,313]	[0,0]	-7	hSpCas9	positive selection	3384146
46695638	46695661	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	1.0675016525658179	[72,72]	[0,0]	5	hSpCas9	positive selection	3384147
46691108	46691131	16	-	26780180	HT29	viability (Avana library 4 designs)	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	5.4150358400435	[]	[]	9	hSpCas9	negative selection	3446950
46691033	46691056	16	+	26780180	HT29	viability (Avana library 4 designs)	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	3.07539912638008	[]	[]	8	hSpCas9	negative selection	3446951
46691099	46691122	16	+	26780180	HT29	viability (Avana library 4 designs)	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	4.75030788509236	[]	[]	9	hSpCas9	negative selection	3446952
46689747	46689770	16	-	26780180	HT29	viability (Avana library 4 designs)	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	3.0954927492021	[]	[]	8	hSpCas9	negative selection	3446953
46691033	46691056	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-11.8518709974254	[]	[]	-8	hSpCas9	negative selection	3540516
46691099	46691122	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-8.69420155021972	[]	[]	-7	hSpCas9	negative selection	3540517
46691108	46691131	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-16.6069403841016	[]	[]	-9	hSpCas9	negative selection	3540518
46689747	46689770	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-3.06726913993746	[]	[]	-4	hSpCas9	negative selection	3540519
46691041	46691064	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGTCTCCGTGGTGCGTGCGG	ORC6	ENSG00000091651	-9.53488917020536	[]	[]	-7	hSpCas9	negative selection	3540520
46691084	46691107	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTTCATCCAGGAAGCTGCAAGG	ORC6	ENSG00000091651	-13.6705686938778	[]	[]	-8	hSpCas9	negative selection	3540521
46691033	46691056	16	+	26780180	A375	viability (Avana lentiGuide)	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	12.5682080401382	[]	[]	7	hSpCas9	negative selection	3649175
46691099	46691122	16	+	26780180	A375	viability (Avana lentiGuide)	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	26.9898763687738	[]	[]	9	hSpCas9	negative selection	3649176
46691108	46691131	16	-	26780180	A375	viability (Avana lentiGuide)	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	16.112687962702	[]	[]	8	hSpCas9	negative selection	3649177
46689747	46689770	16	-	26780180	A375	viability (Avana lentiGuide)	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	4.81952681965986	[]	[]	4	hSpCas9	negative selection	3649178
46691041	46691064	16	-	26780180	A375	viability (Avana lentiGuide)	GCTGGTCTCCGTGGTGCGTGCGG	ORC6	ENSG00000091651	12.5453662406855	[]	[]	7	hSpCas9	negative selection	3649179
46691084	46691107	16	-	26780180	A375	viability (Avana lentiGuide)	ACTTCATCCAGGAAGCTGCAAGG	ORC6	ENSG00000091651	16.8922447100476	[]	[]	8	hSpCas9	negative selection	3649180
46691033	46691056	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.0558932791744018	[5]	[2,1]	-9	hSpCas9	positive selection	3757834
46691099	46691122	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-0.5868635732867038	[5]	[2,3]	-7	hSpCas9	positive selection	3757835
46691108	46691131	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-1.6648760515304954	[4]	[0,0]	-9	hSpCas9	positive selection	3757836
46689747	46689770	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-0.13230537721938535	[5]	[5,3]	-2	hSpCas9	positive selection	3757837
46691041	46691064	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGTCTCCGTGGTGCGTGCGG	ORC6	ENSG00000091651	-0.39454021833027364	[5]	[2,4]	-5	hSpCas9	positive selection	3757838
46691084	46691107	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTTCATCCAGGAAGCTGCAAGG	ORC6	ENSG00000091651	-0.7584745964245264	[4]	[1,2]	-8	hSpCas9	positive selection	3757839
46691033	46691056	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.6139068843517264	[6]	[1,5]	-7	hSpCas9	positive selection	3866441
46691099	46691122	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-1.669060250515249	[5]	[0,0]	-9	hSpCas9	positive selection	3866442
46691108	46691131	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-0.779829080087916	[4]	[0,2]	-7	hSpCas9	positive selection	3866443
46689747	46689770	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-0.7543102667356691	[6]	[2,2]	-7	hSpCas9	positive selection	3866444
46691041	46691064	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGTCTCCGTGGTGCGTGCGG	ORC6	ENSG00000091651	-0.46802023755809274	[6]	[2,5]	-6	hSpCas9	positive selection	3866445
46691084	46691107	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTTCATCCAGGAAGCTGCAAGG	ORC6	ENSG00000091651	-0.23213723741530154	[5]	[3,3]	-3	hSpCas9	positive selection	3866446
46695587	46695610	16	+	26780180	A375	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	1.86388525172992	[]	[]	9	hSpCas9	negative selection	3977355
46693111	46693134	16	-	26780180	A375	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.96206463653977	[]	[]	4	hSpCas9	negative selection	3977356
46691033	46691056	16	+	26780180	A375	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	1.69581699384944	[]	[]	9	hSpCas9	negative selection	3977357
46692486	46692509	16	-	26780180	A375	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	2.56748199087384	[]	[]	9	hSpCas9	negative selection	3977358
46691036	46691059	16	-	26780180	A375	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	1.34104167482611	[]	[]	7	hSpCas9	negative selection	3977359
46695638	46695661	16	+	26780180	A375	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	0.974302165577879	[]	[]	4	hSpCas9	negative selection	3977360
46695587	46695610	16	+	26780180	HT29	viability (GeCKOv2 library)	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	1.88919733543402	[]	[]	9	hSpCas9	negative selection	4085321
46693111	46693134	16	-	26780180	HT29	viability (GeCKOv2 library)	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	1.20659806630303	[]	[]	6	hSpCas9	negative selection	4085322
46691033	46691056	16	+	26780180	HT29	viability (GeCKOv2 library)	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	2.64622459388224	[]	[]	9	hSpCas9	negative selection	4085323
46692486	46692509	16	-	26780180	HT29	viability (GeCKOv2 library)	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	3.45326545293686	[]	[]	9	hSpCas9	negative selection	4085324
46691036	46691059	16	-	26780180	HT29	viability (GeCKOv2 library)	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	2.0929529562013	[]	[]	9	hSpCas9	negative selection	4085325
46695638	46695661	16	+	26780180	HT29	viability (GeCKOv2 library)	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	1.24705005473667	[]	[]	6	hSpCas9	negative selection	4085326
46691033	46691056	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.08969112004813136	[3]	[2,1]	-2	hSpCas9	positive selection	4158110
46692504	46692527	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-0.060807736575422155	[1]	[0,1]	-1	hSpCas9	positive selection	4158111
46692486	46692509	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-0.024309612819034543	[1]	[0,0]	0	hSpCas9	positive selection	4158112
46691036	46691059	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.54705436099166	[2]	[0,0]	-9	hSpCas9	positive selection	4158113
46691033	46691056	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	0.2701593460643317	[3]	[2,3,3,0]	2	hSpCas9	positive selection	4222132
46692504	46692527	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-0.7307934710275281	[2]	[0,0,0,0]	-8	hSpCas9	positive selection	4222133
46692486	46692509	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.115358441018636	[4]	[0,0,0,0]	-9	hSpCas9	positive selection	4222134
46691036	46691059	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	2.33361378619967	[0]	[0,2,0,4]	9	hSpCas9	positive selection	4222135
46691033	46691056	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.3046811283727846	[2]	[1,0]	-6	hSpCas9	positive selection	4288265
46691036	46691059	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.7348701857118701	[2]	[1,0]	-9	hSpCas9	positive selection	4288266
46695587	46695610	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.3770642446858129	[3]	[2,1]	-7	hSpCas9	positive selection	4288267
46692486	46692509	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	0.09436959073850087	[3]	[2,3]	2	hSpCas9	positive selection	4352520
46693111	46693134	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	-0.12053316354251434	[3]	[3,1]	-2	hSpCas9	positive selection	4352521
46695638	46695661	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.4589480619644152	[1]	[1,0]	-7	hSpCas9	positive selection	4352522
46691017	46691039	16	-	27760321	OCIAML3	viability	AGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-1.9072940568771775	[968,664]	[110,242]	-9	hSpCas9	negative selection	4424745
46691109	46691131	16	-	27760321	OCIAML3	viability	ACCTACTTACCCTGTCCAAGGG	ORC6	ENSG00000091651	-0.935644047949425	[572,470]	[178,255]	-7	hSpCas9	negative selection	4424746
46692486	46692508	16	-	27760321	OCIAML3	viability	ACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-3.432263431435352	[344,274]	[7,40]	-9	hSpCas9	negative selection	4424747
46692505	46692527	16	+	27760321	OCIAML3	viability	TGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-1.3242379722101476	[68,55]	[8,32]	-8	hSpCas9	negative selection	4424748
46692525	46692547	16	+	27760321	OCIAML3	viability	GGCTTCAAAGATACTAAAAAGG	ORC6	ENSG00000091651	-2.359621231008324	[5,6]	[0,0]	-9	hSpCas9	negative selection	4424749
46691017	46691039	16	-	27760321	OCIAML2	viability	AGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-1.922829969199015	[968,664]	[160,186]	-9	hSpCas9	negative selection	4508208
46691109	46691131	16	-	27760321	OCIAML2	viability	ACCTACTTACCCTGTCCAAGGG	ORC6	ENSG00000091651	-1.8175704808851934	[572,470]	[126,108]	-9	hSpCas9	negative selection	4508209
46692486	46692508	16	-	27760321	OCIAML2	viability	ACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-2.8881249109969174	[344,274]	[18,52]	-9	hSpCas9	negative selection	4508210
46692505	46692527	16	+	27760321	OCIAML2	viability	TGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-5.652331167379785	[68,55]	[0,0]	-9	hSpCas9	negative selection	4508211
46692525	46692547	16	+	27760321	OCIAML2	viability	GGCTTCAAAGATACTAAAAAGG	ORC6	ENSG00000091651	-2.408366596273373	[5,6]	[0,0]	-9	hSpCas9	negative selection	4508212
46691017	46691039	16	-	27760321	MV411	viability	AGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-0.5590737757608668	[968,664]	[297,456]	-4	hSpCas9	negative selection	4591671
46691109	46691131	16	-	27760321	MV411	viability	ACCTACTTACCCTGTCCAAGGG	ORC6	ENSG00000091651	-1.7529463665926364	[572,470]	[2,249]	-8	hSpCas9	negative selection	4591672
46692486	46692508	16	-	27760321	MV411	viability	ACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-0.9976622157272631	[344,274]	[146,33]	-6	hSpCas9	negative selection	4591673
46692505	46692527	16	+	27760321	MV411	viability	TGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-1.7507966188009862	[68,55]	[0,28]	-8	hSpCas9	negative selection	4591674
46692525	46692547	16	+	27760321	MV411	viability	GGCTTCAAAGATACTAAAAAGG	ORC6	ENSG00000091651	-2.1145426620936423	[5,6]	[0,0]	-8	hSpCas9	negative selection	4591675
46691017	46691039	16	-	27760321	HL60	viability	AGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.2581230781504273	[968,664]	[115,160]	-9	hSpCas9	negative selection	4675134
46691109	46691131	16	-	27760321	HL60	viability	ACCTACTTACCCTGTCCAAGGG	ORC6	ENSG00000091651	-2.9497560854594456	[572,470]	[35,74]	-9	hSpCas9	negative selection	4675135
46692486	46692508	16	-	27760321	HL60	viability	ACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.4908637747131626	[344,274]	[74,104]	-8	hSpCas9	negative selection	4675136
46692505	46692527	16	+	27760321	HL60	viability	TGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-0.4761394445984406	[68,55]	[69,0]	-5	hSpCas9	negative selection	4675137
46692525	46692547	16	+	27760321	HL60	viability	GGCTTCAAAGATACTAAAAAGG	ORC6	ENSG00000091651	-2.422412823887779	[5,6]	[0,0]	-9	hSpCas9	negative selection	4675138
46691017	46691039	16	-	27760321	HT1080	viability	AGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-4.188560823013152	[664,518]	[0,25]	-8	hSpCas9	negative selection	4758597
46691109	46691131	16	-	27760321	HT1080	viability	ACCTACTTACCCTGTCCAAGGG	ORC6	ENSG00000091651	-7.3848074695953745	[470,367]	[0,0]	-9	hSpCas9	negative selection	4758598
46692486	46692508	16	-	27760321	HT1080	viability	ACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-6.6089757488120675	[274,214]	[0,0]	-9	hSpCas9	negative selection	4758599
46692505	46692527	16	+	27760321	HT1080	viability	TGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-4.316638003739513	[55,43]	[0,0]	-8	hSpCas9	negative selection	4758600
46692525	46692547	16	+	27760321	HT1080	viability	GGCTTCAAAGATACTAAAAAGG	ORC6	ENSG00000091651	-1.3810091929335382	[6,5]	[0,0]	-5	hSpCas9	negative selection	4758601
46691017	46691039	16	-	27760321	HT29	viability after 7 days	AGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-1.3399205827661178	[664,518]	[364,251,293]	-9	hSpCas9	negative selection	4842060
46691109	46691131	16	-	27760321	HT29	viability after 7 days	ACCTACTTACCCTGTCCAAGGG	ORC6	ENSG00000091651	-1.1290893878444028	[470,367]	[358,260,138]	-8	hSpCas9	negative selection	4842061
46692486	46692508	16	-	27760321	HT29	viability after 7 days	ACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.6336672504940999	[274,214]	[81,192,28]	-9	hSpCas9	negative selection	4842062
46692505	46692527	16	+	27760321	HT29	viability after 7 days	TGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-3.817158154260087	[55,43]	[12,0,0]	-9	hSpCas9	negative selection	4842063
46692525	46692547	16	+	27760321	HT29	viability after 7 days	GGCTTCAAAGATACTAAAAAGG	ORC6	ENSG00000091651	0.07562793841126947	[6,5]	[6,0,17]	1	hSpCas9	negative selection	4842064
46691017	46691039	16	-	27760321	HT29	viability after 25 days	AGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.3026654919153553	[664,518]	[74,220,116]	-8	hSpCas9	negative selection	4925523
46691109	46691131	16	-	27760321	HT29	viability after 25 days	ACCTACTTACCCTGTCCAAGGG	ORC6	ENSG00000091651	-4.838734871116575	[470,367]	[0,0,52]	-9	hSpCas9	negative selection	4925524
46692486	46692508	16	-	27760321	HT29	viability after 25 days	ACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-8.128658013658592	[274,214]	[0,0,0]	-9	hSpCas9	negative selection	4925525
46692505	46692527	16	+	27760321	HT29	viability after 25 days	TGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-4.903934048801975	[55,43]	[0,0,3]	-9	hSpCas9	negative selection	4925526
46692525	46692547	16	+	27760321	HT29	viability after 25 days	GGCTTCAAAGATACTAAAAAGG	ORC6	ENSG00000091651	-2.900691457780062	[6,5]	[0,0,0]	-8	hSpCas9	negative selection	4925527
46691017	46691039	16	-	27760321	HT29	viability after 22 days	AGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.338718426344355	[664,518]	[97,160,147]	-8	hSpCas9	negative selection	5008986
46691109	46691131	16	-	27760321	HT29	viability after 22 days	ACCTACTTACCCTGTCCAAGGG	ORC6	ENSG00000091651	-5.606220287518626	[470,367]	[2,22,3]	-9	hSpCas9	negative selection	5008987
46692486	46692508	16	-	27760321	HT29	viability after 22 days	ACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-6.5451587434659455	[274,214]	[5,1,0]	-9	hSpCas9	negative selection	5008988
46692505	46692527	16	+	27760321	HT29	viability after 22 days	TGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-5.853638900445295	[55,43]	[0,0,0]	-9	hSpCas9	negative selection	5008989
46692525	46692547	16	+	27760321	HT29	viability after 22 days	GGCTTCAAAGATACTAAAAAGG	ORC6	ENSG00000091651	-2.9180100896393215	[6,5]	[0,0,0]	-8	hSpCas9	negative selection	5008990
46691017	46691039	16	-	27760321	HT29	viability after 19 days	AGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.020568453615598	[664,518]	[70,293,126]	-8	hSpCas9	negative selection	5092449
46691109	46691131	16	-	27760321	HT29	viability after 19 days	ACCTACTTACCCTGTCCAAGGG	ORC6	ENSG00000091651	-8.905968313877944	[470,367]	[0,0,0]	-9	hSpCas9	negative selection	5092450
46692486	46692508	16	-	27760321	HT29	viability after 19 days	ACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-7.120638812032049	[274,214]	[1,0,2]	-9	hSpCas9	negative selection	5092451
46692505	46692527	16	+	27760321	HT29	viability after 19 days	TGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-5.837798848022082	[55,43]	[0,0,0]	-9	hSpCas9	negative selection	5092452
46692525	46692547	16	+	27760321	HT29	viability after 19 days	GGCTTCAAAGATACTAAAAAGG	ORC6	ENSG00000091651	-2.9021700372161083	[6,5]	[0,0,0]	-8	hSpCas9	negative selection	5092453
46691017	46691039	16	-	27760321	HT29	viability after 16 days	AGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.0912978646860356	[664,518]	[87,112,259]	-8	hSpCas9	negative selection	5175912
46691109	46691131	16	-	27760321	HT29	viability after 16 days	ACCTACTTACCCTGTCCAAGGG	ORC6	ENSG00000091651	-3.725126693941314	[470,367]	[0,81,18]	-9	hSpCas9	negative selection	5175913
46692486	46692508	16	-	27760321	HT29	viability after 16 days	ACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-5.230732242110994	[274,214]	[0,18,0]	-9	hSpCas9	negative selection	5175914
46692505	46692527	16	+	27760321	HT29	viability after 16 days	TGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-5.80633439560116	[55,43]	[0,0,0]	-9	hSpCas9	negative selection	5175915
46692525	46692547	16	+	27760321	HT29	viability after 16 days	GGCTTCAAAGATACTAAAAAGG	ORC6	ENSG00000091651	-2.8707055847951866	[6,5]	[0,0,0]	-9	hSpCas9	negative selection	5175916
46691017	46691039	16	-	27760321	HT29	viability after 13 days	AGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.3913495575386565	[664,518]	[178,106,107]	-9	hSpCas9	negative selection	5259375
46691109	46691131	16	-	27760321	HT29	viability after 13 days	ACCTACTTACCCTGTCCAAGGG	ORC6	ENSG00000091651	-3.7766437570955644	[470,367]	[6,87,12]	-9	hSpCas9	negative selection	5259376
46692486	46692508	16	-	27760321	HT29	viability after 13 days	ACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-5.052104861273416	[274,214]	[2,18,3]	-9	hSpCas9	negative selection	5259377
46692505	46692527	16	+	27760321	HT29	viability after 13 days	TGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-3.8160640267588053	[55,43]	[0,0,9]	-9	hSpCas9	negative selection	5259378
46692525	46692547	16	+	27760321	HT29	viability after 13 days	GGCTTCAAAGATACTAAAAAGG	ORC6	ENSG00000091651	-2.9229929842393245	[6,5]	[0,0,0]	-9	hSpCas9	negative selection	5259379
46691017	46691039	16	-	27760321	HT29	viability after 10 days	AGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.4514126825180704	[664,518]	[75,293,41]	-9	hSpCas9	negative selection	5342838
46691109	46691131	16	-	27760321	HT29	viability after 10 days	ACCTACTTACCCTGTCCAAGGG	ORC6	ENSG00000091651	-3.8163017948761166	[470,367]	[10,37,61]	-9	hSpCas9	negative selection	5342839
46692486	46692508	16	-	27760321	HT29	viability after 10 days	ACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-4.472954969973001	[274,214]	[0,32,7]	-9	hSpCas9	negative selection	5342840
46692505	46692527	16	+	27760321	HT29	viability after 10 days	TGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-1.7922675130617978	[55,43]	[51,0,0]	-9	hSpCas9	negative selection	5342841
46692525	46692547	16	+	27760321	HT29	viability after 10 days	GGCTTCAAAGATACTAAAAAGG	ORC6	ENSG00000091651	-3.0290042913996684	[6,5]	[0,0,0]	-9	hSpCas9	negative selection	5342842
46691017	46691039	16	-	27760321	MOLM13	viability	AGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-0.8207399579169724	[968,664]	[64,421]	-5	hSpCas9	negative selection	5426301
46691109	46691131	16	-	27760321	MOLM13	viability	ACCTACTTACCCTGTCCAAGGG	ORC6	ENSG00000091651	-2.1804610849445374	[572,470]	[122,14]	-8	hSpCas9	negative selection	5426302
46692486	46692508	16	-	27760321	MOLM13	viability	ACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-0.7773935939500597	[344,274]	[135,71]	-5	hSpCas9	negative selection	5426303
46692505	46692527	16	+	27760321	MOLM13	viability	TGTATAGAAGCAGTGAACATGG	ORC6	ENSG00000091651	-5.132450420372459	[68,55]	[0,0]	-9	hSpCas9	negative selection	5426304
46692525	46692547	16	+	27760321	MOLM13	viability	GGCTTCAAAGATACTAAAAAGG	ORC6	ENSG00000091651	-1.888485849266047	[5,6]	[0,0]	-8	hSpCas9	negative selection	5426305
46689992	46690015	16	+	27661255	K562	viability	GAACAGCCAGCCCTGTCCGTGGG	ORC6	ENSG00000091651	-0.009179277287207799	[1404,1516]	[1258,1071]	0	dCas9-KRAB	negative selection	5499517
46690128	46690151	16	+	27661255	K562	viability	GGACTGTGTAGACCTTAACCGGG	ORC6	ENSG00000091651	-0.19146834661338286	[203,259]	[173,150]	-6	dCas9-KRAB	negative selection	5499518
46689735	46689758	16	-	27661255	K562	viability	GCTCGGCGAGGCCCAGGCGCGGG	ORC6	ENSG00000091651	-0.6061544941060164	[241,262]	[188,83]	-8	dCas9-KRAB	negative selection	5499519
46690041	46690064	16	-	27661255	K562	viability	GTAGGCGTTGGCGGAATGAACGG	ORC6	ENSG00000091651	0.0582724485378866	[1153,1252]	[1046,958]	2	dCas9-KRAB	negative selection	5499520
46691033	46691056	16	+	27260156	BXPC3	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.5336017714448569	[295]	[132,260,214,255]	-8	hSpCas9	negative selection	5560725
46691036	46691059	16	-	27260156	BXPC3	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.7515494962789856	[249]	[82,163,214,167]	-9	hSpCas9	negative selection	5560726
46695587	46695610	16	+	27260156	BXPC3	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.03624379279973433	[742]	[578,796,854,999]	0	hSpCas9	negative selection	5560727
46692486	46692509	16	-	27260156	BXPC3	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.1643192388182952	[976]	[493,439,302,593]	-9	hSpCas9	negative selection	5624980
46693111	46693134	16	-	27260156	BXPC3	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.21823975864444733	[666]	[740,856,849,794]	5	hSpCas9	negative selection	5624981
46695638	46695661	16	+	27260156	BXPC3	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.27036330405819475	[181]	[134,156,182,157]	-6	hSpCas9	negative selection	5624982
46691033	46691056	16	+	27260156	A673	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.4602122090781957	[295]	[324,268,230,212]	-8	hSpCas9	negative selection	5681976
46691036	46691059	16	-	27260156	A673	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.7528539390326808	[249]	[100,175,184,244]	-9	hSpCas9	negative selection	5681977
46695587	46695610	16	+	27260156	A673	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.36196076479563744	[742]	[835,591,636,731]	-7	hSpCas9	negative selection	5681978
46692486	46692509	16	-	27260156	A673	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.415429332975405	[976]	[484,360,438,482]	-9	hSpCas9	negative selection	5746231
46693111	46693134	16	-	27260156	A673	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.07627516800011036	[666]	[860,790,834,894]	1	hSpCas9	negative selection	5746232
46695638	46695661	16	+	27260156	A673	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.501761190225332	[181]	[133,185,197,91]	-8	hSpCas9	negative selection	5746233
46691033	46691056	16	+	27260156	A375	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.641744225054328	[295]	[75,203,78,97]	-9	hSpCas9	negative selection	5803227
46691036	46691059	16	-	27260156	A375	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.3609912366034957	[249]	[70,70,265,47]	-9	hSpCas9	negative selection	5803228
46695587	46695610	16	+	27260156	A375	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.22015582829478197	[742]	[690,989,697,643]	-3	hSpCas9	negative selection	5803229
46692486	46692509	16	-	27260156	A375	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.4244676725901901	[976]	[353,485,350,505]	-9	hSpCas9	negative selection	5867482
46693111	46693134	16	-	27260156	A375	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.43201845252910553	[666]	[954,1256,909,1099]	6	hSpCas9	negative selection	5867483
46695638	46695661	16	+	27260156	A375	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.9198427386072852	[181]	[138,85,130,91]	-8	hSpCas9	negative selection	5867484
46691033	46691056	16	+	27260156	COLO741	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.751532113898404	[295]	[82,134,115]	-9	hSpCas9	negative selection	5924478
46691036	46691059	16	-	27260156	COLO741	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.3892152952121823	[249]	[193,89,89]	-9	hSpCas9	negative selection	5924479
46695587	46695610	16	+	27260156	COLO741	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.38221898635671203	[742]	[585,651,918]	-7	hSpCas9	negative selection	5924480
46692486	46692509	16	-	27260156	COLO741	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.720017230304888	[976]	[540,224,382]	-9	hSpCas9	negative selection	5988733
46693111	46693134	16	-	27260156	COLO741	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.23802725118890433	[666]	[1141,1094,802]	5	hSpCas9	negative selection	5988734
46695638	46695661	16	+	27260156	COLO741	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.7952392963667734	[181]	[92,152,150]	-9	hSpCas9	negative selection	5988735
46691033	46691056	16	+	27260156	CAL120	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.6603913548737226	[295]	[357,134,224]	-7	hSpCas9	negative selection	6045729
46691036	46691059	16	-	27260156	CAL120	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.6926063340931564	[249]	[226,186,168]	-7	hSpCas9	negative selection	6045730
46695587	46695610	16	+	27260156	CAL120	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.08288526594479873	[742]	[1124,801,731]	-1	hSpCas9	negative selection	6045731
46692486	46692509	16	-	27260156	CAL120	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.7605288850862992	[976]	[432,324,329]	-9	hSpCas9	negative selection	6109984
46693111	46693134	16	-	27260156	CAL120	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.1701791070436095	[666]	[1509,608,771]	2	hSpCas9	negative selection	6109985
46695638	46695661	16	+	27260156	CAL120	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.8244734367993214	[181]	[125,54,200]	-8	hSpCas9	negative selection	6109986
46691033	46691056	16	+	27260156	CADOES1	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.9063731880981862	[295]	[123,170,186,103]	-9	hSpCas9	negative selection	6166980
46691036	46691059	16	-	27260156	CADOES1	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.5953947235308732	[249]	[79,40,101,84]	-9	hSpCas9	negative selection	6166981
46695587	46695610	16	+	27260156	CADOES1	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.014055220444870509	[742]	[598,658,843,688]	0	hSpCas9	negative selection	6166982
46692486	46692509	16	-	27260156	CADOES1	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.6877717306221425	[976]	[115,254,361,399]	-9	hSpCas9	negative selection	6231235
46693111	46693134	16	-	27260156	CADOES1	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.34066472137159454	[666]	[808,881,702,746]	6	hSpCas9	negative selection	6231236
46695638	46695661	16	+	27260156	CADOES1	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.7676240409235344	[181]	[86,138,67,103]	-8	hSpCas9	negative selection	6231237
46691033	46691056	16	+	27260156	EWS502	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.5643275460012946	[295]	[115,97,129,76]	-9	hSpCas9	negative selection	6288231
46691036	46691059	16	-	27260156	EWS502	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.9225260585045548	[249]	[171,120,135,124]	-8	hSpCas9	negative selection	6288232
46695587	46695610	16	+	27260156	EWS502	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.043687352124200496	[742]	[586,772,1011,907]	0	hSpCas9	negative selection	6288233
46692486	46692509	16	-	27260156	EWS502	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-2.051133681839721	[976]	[173,224,192,427]	-9	hSpCas9	negative selection	6352486
46693111	46693134	16	-	27260156	EWS502	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.27513324863457544	[666]	[863,650,964,951]	5	hSpCas9	negative selection	6352487
46695638	46695661	16	+	27260156	EWS502	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.6150256885136889	[181]	[184,117,86,103]	-7	hSpCas9	negative selection	6352488
46691033	46691056	16	+	27260156	EW8	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.2759407120168738	[295]	[114,107,55,125]	-9	hSpCas9	negative selection	6409482
46691036	46691059	16	-	27260156	EW8	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.9598289844182933	[249]	[128,102,134,46]	-9	hSpCas9	negative selection	6409483
46695587	46695610	16	+	27260156	EW8	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.030752469070362	[742]	[785,490,530,682]	0	hSpCas9	negative selection	6409484
46692486	46692509	16	-	27260156	EW8	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.774157717633505	[976]	[271,326,132,214]	-9	hSpCas9	negative selection	6473737
46693111	46693134	16	-	27260156	EW8	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.11178056667220493	[666]	[825,519,520,504]	2	hSpCas9	negative selection	6473738
46695638	46695661	16	+	27260156	EW8	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.8405960726033173	[181]	[71,68,111,69]	-9	hSpCas9	negative selection	6473739
46691033	46691056	16	+	27260156	CORL105	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.5549029470164735	[295]	[298,201,245,200]	-7	hSpCas9	negative selection	6530733
46691036	46691059	16	-	27260156	CORL105	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.9572726562241295	[249]	[109,178,113,191]	-9	hSpCas9	negative selection	6530734
46695587	46695610	16	+	27260156	CORL105	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.17060988998349513	[742]	[844,825,860,574]	-3	hSpCas9	negative selection	6530735
46692486	46692509	16	-	27260156	CORL105	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.4492038965543539	[976]	[395,438,467,378]	-9	hSpCas9	negative selection	6594988
46693111	46693134	16	-	27260156	CORL105	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.2895076889515259	[666]	[941,813,1217,886]	5	hSpCas9	negative selection	6594989
46695638	46695661	16	+	27260156	CORL105	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.9178710460646031	[181]	[152,101,82,109]	-9	hSpCas9	negative selection	6594990
46691033	46691056	16	+	27260156	HS294T	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	0.2862697230401454	[295]	[85,69,311,88]	4	hSpCas9	negative selection	6651984
46691036	46691059	16	-	27260156	HS294T	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.4209846697933877	[249]	[17,31,50,46]	-9	hSpCas9	negative selection	6651985
46695587	46695610	16	+	27260156	HS294T	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.09833034260695783	[742]	[238,444,214,336]	1	hSpCas9	negative selection	6651986
46692486	46692509	16	-	27260156	HS294T	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.4829882841562796	[976]	[107,112,144,185]	-9	hSpCas9	negative selection	6716239
46693111	46693134	16	-	27260156	HS294T	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.4465893369131336	[666]	[280,369,332,441]	6	hSpCas9	negative selection	6716240
46695638	46695661	16	+	27260156	HS294T	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.9887778782398895	[181]	[9,43,43,47]	-8	hSpCas9	negative selection	6716241
46691033	46691056	16	+	27260156	HCC44	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.848980936814874	[295]	[158,76,244,280]	-8	hSpCas9	negative selection	6773235
46691036	46691059	16	-	27260156	HCC44	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.250932294418683	[249]	[66,65,160,187]	-9	hSpCas9	negative selection	6773236
46695587	46695610	16	+	27260156	HCC44	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.009235571050661862	[742]	[745,606,1353,742]	0	hSpCas9	negative selection	6773237
46692486	46692509	16	-	27260156	HCC44	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-2.171301698526557	[976]	[480,134,217,179]	-9	hSpCas9	negative selection	6837490
46693111	46693134	16	-	27260156	HCC44	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.16738418990550863	[666]	[761,832,981,822]	2	hSpCas9	negative selection	6837491
46695638	46695661	16	+	27260156	HCC44	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-1.0079710140125253	[181]	[130,86,113,83]	-8	hSpCas9	negative selection	6837492
46691033	46691056	16	+	27260156	G402	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.8612989041110783	[295]	[59,61,159,106]	-9	hSpCas9	negative selection	6894486
46691036	46691059	16	-	27260156	G402	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-2.1387714392993424	[249]	[34,24,133,74]	-9	hSpCas9	negative selection	6894487
46695587	46695610	16	+	27260156	G402	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.028638350761569953	[742]	[843,829,774,1214]	0	hSpCas9	negative selection	6894488
46692486	46692509	16	-	27260156	G402	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.6999220627526257	[976]	[646,347,107,400]	-9	hSpCas9	negative selection	6958741
46693111	46693134	16	-	27260156	G402	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.11041662220545279	[666]	[1062,1042,748,700]	1	hSpCas9	negative selection	6958742
46695638	46695661	16	+	27260156	G402	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.8340303169823593	[181]	[48,394,47,15]	-7	hSpCas9	negative selection	6958743
46691033	46691056	16	+	27260156	L33	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.7070424037083121	[295]	[140,55,119,256]	-9	hSpCas9	negative selection	7015737
46691036	46691059	16	-	27260156	L33	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.7265949191850251	[249]	[203,39,61,201]	-9	hSpCas9	negative selection	7015738
46695587	46695610	16	+	27260156	L33	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.18699079925208295	[742]	[862,391,478,800]	4	hSpCas9	negative selection	7015739
46692486	46692509	16	-	27260156	L33	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.669728722585607	[976]	[274,141,156,356]	-9	hSpCas9	negative selection	7079992
46693111	46693134	16	-	27260156	L33	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.06939592606888423	[666]	[687,229,576,633]	1	hSpCas9	negative selection	7079993
46695638	46695661	16	+	27260156	L33	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	0.05637903637518127	[181]	[239,62,137,142]	1	hSpCas9	negative selection	7079994
46691033	46691056	16	+	27260156	K562	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.0574217078735781	[295]	[92,58,39,286]	-8	hSpCas9	negative selection	7136988
46691036	46691059	16	-	27260156	K562	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-2.5576519476266784	[249]	[33,52,53,12]	-9	hSpCas9	negative selection	7136989
46695587	46695610	16	+	27260156	K562	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.033344688089512964	[742]	[745,838,802,359]	0	hSpCas9	negative selection	7136990
46692486	46692509	16	-	27260156	K562	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-2.1239513423948706	[976]	[78,291,192,222]	-9	hSpCas9	negative selection	7201243
46693111	46693134	16	-	27260156	K562	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.38729368470557946	[666]	[680,640,1040,721]	5	hSpCas9	negative selection	7201244
46695638	46695661	16	+	27260156	K562	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.895505687138431	[181]	[135,98,61,57]	-7	hSpCas9	negative selection	7201245
46691033	46691056	16	+	27260156	HT29	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.869277657300622	[295]	[151,81,99,65]	-9	hSpCas9	negative selection	7258239
46691036	46691059	16	-	27260156	HT29	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.9538935170611134	[249]	[98,75,64,74]	-9	hSpCas9	negative selection	7258240
46695587	46695610	16	+	27260156	HT29	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.16439431728029397	[742]	[853,780,801,784]	-3	hSpCas9	negative selection	7258241
46692486	46692509	16	-	27260156	HT29	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-2.3931523586284484	[976]	[303,170,265,169]	-9	hSpCas9	negative selection	7322494
46693111	46693134	16	-	27260156	HT29	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.10971670151012913	[666]	[953,980,892,701]	2	hSpCas9	negative selection	7322495
46695638	46695661	16	+	27260156	HT29	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.8082638904433836	[181]	[167,146,144,57]	-8	hSpCas9	negative selection	7322496
46691033	46691056	16	+	27260156	MHHES1	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.7900705768277421	[295]	[114,247,85,289]	-9	hSpCas9	negative selection	7379490
46691036	46691059	16	-	27260156	MHHES1	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.5412391791957262	[249]	[350,233,96,125]	-7	hSpCas9	negative selection	7379491
46695587	46695610	16	+	27260156	MHHES1	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.3049243672528393	[742]	[902,573,738,529]	-5	hSpCas9	negative selection	7379492
46692486	46692509	16	-	27260156	MHHES1	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.2524199784245786	[976]	[394,616,340,484]	-9	hSpCas9	negative selection	7443745
46693111	46693134	16	-	27260156	MHHES1	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.321183463057254	[666]	[1125,1027,850,792]	6	hSpCas9	negative selection	7443746
46695638	46695661	16	+	27260156	MHHES1	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.6555076395773201	[181]	[182,29,266,52]	-8	hSpCas9	negative selection	7443747
46691033	46691056	16	+	27260156	MEWO	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.1977652770151452	[295]	[175,91,104]	-9	hSpCas9	negative selection	7500741
46691036	46691059	16	-	27260156	MEWO	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.3033058908640163	[249]	[133,72,84]	-9	hSpCas9	negative selection	7500742
46695587	46695610	16	+	27260156	MEWO	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.04539992058341358	[742]	[984,661,556]	1	hSpCas9	negative selection	7500743
46692486	46692509	16	-	27260156	MEWO	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.5284648684919875	[976]	[432,312,226]	-9	hSpCas9	negative selection	7564996
46693111	46693134	16	-	27260156	MEWO	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	-0.012008139160077314	[666]	[663,649,550]	0	hSpCas9	negative selection	7564997
46695638	46695661	16	+	27260156	MEWO	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.2802579420582838	[181]	[151,115,154]	-6	hSpCas9	negative selection	7564998
46691033	46691056	16	+	27260156	LNCAPCLONEFGC	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.8896660812132933	[295]	[111,47,90,41]	-9	hSpCas9	negative selection	7621992
46691036	46691059	16	-	27260156	LNCAPCLONEFGC	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.0907926812391704	[249]	[102,95,92,131]	-9	hSpCas9	negative selection	7621993
46695587	46695610	16	+	27260156	LNCAPCLONEFGC	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.11149997193382521	[742]	[579,601,819,520]	-2	hSpCas9	negative selection	7621994
46692486	46692509	16	-	27260156	LNCAPCLONEFGC	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.688792798675558	[976]	[278,214,255,348]	-9	hSpCas9	negative selection	7686247
46693111	46693134	16	-	27260156	LNCAPCLONEFGC	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.19984391058251272	[666]	[663,758,668,675]	3	hSpCas9	negative selection	7686248
46695638	46695661	16	+	27260156	LNCAPCLONEFGC	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	0.0907924511211442	[181]	[193,110,147,248]	1	hSpCas9	negative selection	7686249
46691033	46691056	16	+	27260156	PANC0327	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.7941427892532038	[295]	[55,19,172,59]	-9	hSpCas9	negative selection	7743243
46691036	46691059	16	-	27260156	PANC0327	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.9252821199455684	[249]	[181,47,137,113]	-8	hSpCas9	negative selection	7743244
46695587	46695610	16	+	27260156	PANC0327	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.28919105973243575	[742]	[746,516,366,548]	-4	hSpCas9	negative selection	7743245
46692486	46692509	16	-	27260156	PANC0327	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-0.47667589812925726	[976]	[361,596,1319,198]	-6	hSpCas9	negative selection	7807498
46693111	46693134	16	-	27260156	PANC0327	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.24340136188336758	[666]	[756,589,1020,456]	3	hSpCas9	negative selection	7807499
46695638	46695661	16	+	27260156	PANC0327	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.49486137672895536	[181]	[44,138,114,150]	-6	hSpCas9	negative selection	7807500
46691033	46691056	16	+	27260156	NCIH2009	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.9545450572418435	[295]	[109,137,71]	-9	hSpCas9	negative selection	7864494
46691036	46691059	16	-	27260156	NCIH2009	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.630129432369551	[249]	[95,112,125]	-9	hSpCas9	negative selection	7864495
46695587	46695610	16	+	27260156	NCIH2009	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.1716705493473858	[742]	[1081,1087,621]	-2	hSpCas9	negative selection	7864496
46692486	46692509	16	-	27260156	NCIH2009	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-2.208749715488586	[976]	[328,240,322]	-9	hSpCas9	negative selection	7928749
46693111	46693134	16	-	27260156	NCIH2009	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.3438445161745034	[666]	[1234,1207,1112]	5	hSpCas9	negative selection	7928750
46695638	46695661	16	+	27260156	NCIH2009	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.7985809205000276	[181]	[129,152,151]	-7	hSpCas9	negative selection	7928751
46691033	46691056	16	+	27260156	NCIH1373	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.9151116569702611	[295]	[223,164,238,19]	-7	hSpCas9	negative selection	7985745
46691036	46691059	16	-	27260156	NCIH1373	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-2.0853257596073784	[249]	[50,104,78,4]	-9	hSpCas9	negative selection	7985746
46695587	46695610	16	+	27260156	NCIH1373	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.15670980010845503	[742]	[1126,759,990,229]	1	hSpCas9	negative selection	7985747
46692486	46692509	16	-	27260156	NCIH1373	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.415970955260072	[976]	[356,417,376,126]	-8	hSpCas9	negative selection	8050000
46693111	46693134	16	-	27260156	NCIH1373	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.22735680845077977	[666]	[1080,848,749,223]	2	hSpCas9	negative selection	8050001
46695638	46695661	16	+	27260156	NCIH1373	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-1.4344197551251634	[181]	[128,89,59,6]	-8	hSpCas9	negative selection	8050002
46691033	46691056	16	+	27260156	PATU8902	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.2114411198116208	[295]	[185,306,138,76]	-8	hSpCas9	negative selection	8106996
46691036	46691059	16	-	27260156	PATU8902	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.7433928561624171	[249]	[337,152,16,391]	-6	hSpCas9	negative selection	8106997
46695587	46695610	16	+	27260156	PATU8902	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.19578471274415526	[742]	[854,959,857,951]	-2	hSpCas9	negative selection	8106998
46692486	46692509	16	-	27260156	PATU8902	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-2.819298673534938	[976]	[163,52,336,175]	-9	hSpCas9	negative selection	8171251
46693111	46693134	16	-	27260156	PATU8902	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.6130357064918527	[666]	[1706,1906,556,1763]	6	hSpCas9	negative selection	8171252
46695638	46695661	16	+	27260156	PATU8902	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-1.24137600630513	[181]	[11,36,177,193]	-8	hSpCas9	negative selection	8171253
46691033	46691056	16	+	27260156	PANC1	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-2.466256558418757	[295]	[21,23,76,54]	-9	hSpCas9	negative selection	8228247
46691036	46691059	16	-	27260156	PANC1	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-2.6696514084063523	[249]	[41,23,30,34]	-9	hSpCas9	negative selection	8228248
46695587	46695610	16	+	27260156	PANC1	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.25862077358399893	[742]	[915,917,641,616]	4	hSpCas9	negative selection	8228249
46692486	46692509	16	-	27260156	PANC1	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-3.043268755791874	[976]	[97,112,102,94]	-9	hSpCas9	negative selection	8292502
46693111	46693134	16	-	27260156	PANC1	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.307976778323954	[666]	[625,1097,704,510]	5	hSpCas9	negative selection	8292503
46695638	46695661	16	+	27260156	PANC1	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-1.0307035068273414	[181]	[89,62,47,96]	-8	hSpCas9	negative selection	8292504
46691033	46691056	16	+	27260156	PANC0813	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.4214448544392886	[295]	[65,272,101,74]	-9	hSpCas9	negative selection	8349498
46691036	46691059	16	-	27260156	PANC0813	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.769421383818996	[249]	[75,74,147,46]	-9	hSpCas9	negative selection	8349499
46695587	46695610	16	+	27260156	PANC0813	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.14541742403400493	[742]	[834,761,649,904]	-2	hSpCas9	negative selection	8349500
46692486	46692509	16	-	27260156	PANC0813	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.6792595842179185	[976]	[305,394,300,421]	-9	hSpCas9	negative selection	8413753
46693111	46693134	16	-	27260156	PANC0813	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.17847691560245516	[666]	[991,734,936,890]	3	hSpCas9	negative selection	8413754
46695638	46695661	16	+	27260156	PANC0813	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-1.274326373568904	[181]	[87,129,78,57]	-9	hSpCas9	negative selection	8413755
46691033	46691056	16	+	27260156	RDES	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.3989437198715293	[295]	[120,79,162,160]	-9	hSpCas9	negative selection	8470749
46691036	46691059	16	-	27260156	RDES	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.2394697487166004	[249]	[138,106,88,147]	-9	hSpCas9	negative selection	8470750
46695587	46695610	16	+	27260156	RDES	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.186426856125245	[742]	[560,820,802,846]	-3	hSpCas9	negative selection	8470751
46692486	46692509	16	-	27260156	RDES	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.8874825753513236	[976]	[259,264,340,362]	-9	hSpCas9	negative selection	8535004
46693111	46693134	16	-	27260156	RDES	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.31530386365656027	[666]	[802,886,1062,1100]	5	hSpCas9	negative selection	8535005
46695638	46695661	16	+	27260156	RDES	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.9330076658293942	[181]	[73,104,115,155]	-9	hSpCas9	negative selection	8535006
46691033	46691056	16	+	27260156	PC3	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.6631184763150824	[295]	[95,180,413,166]	-9	hSpCas9	negative selection	8592000
46691036	46691059	16	-	27260156	PC3	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.7643826441401386	[249]	[95,240,149,99]	-9	hSpCas9	negative selection	8592001
46695587	46695610	16	+	27260156	PC3	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.36963555169763196	[742]	[675,811,1678,970]	7	hSpCas9	negative selection	8592002
46692486	46692509	16	-	27260156	PC3	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.85427178364702	[976]	[116,221,471,401]	-9	hSpCas9	negative selection	8656255
46693111	46693134	16	-	27260156	PC3	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.029316144853987924	[666]	[490,616,1135,657]	0	hSpCas9	negative selection	8656256
46695638	46695661	16	+	27260156	PC3	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	0.20460864649244948	[181]	[114,269,317,193]	4	hSpCas9	negative selection	8656257
46691033	46691056	16	+	27260156	PATU8988T	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.48577174836481807	[295]	[153,197,157,315]	-7	hSpCas9	negative selection	8713251
46691036	46691059	16	-	27260156	PATU8988T	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.6300850791825069	[249]	[185,149,132,154]	-7	hSpCas9	negative selection	8713252
46695587	46695610	16	+	27260156	PATU8988T	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.2345995023962678	[742]	[1057,696,854,746]	4	hSpCas9	negative selection	8713253
46692486	46692509	16	-	27260156	PATU8988T	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.7995177249796401	[976]	[226,332,158,381]	-9	hSpCas9	negative selection	8777506
46693111	46693134	16	-	27260156	PATU8988T	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.31826435624959104	[666]	[829,788,771,823]	5	hSpCas9	negative selection	8777507
46695638	46695661	16	+	27260156	PATU8988T	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.06007144517482632	[181]	[144,222,154,155]	-1	hSpCas9	negative selection	8777508
46691033	46691056	16	+	27260156	T47D	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.616094476297609	[295]	[103,94,118,133]	-9	hSpCas9	negative selection	8834502
46691036	46691059	16	-	27260156	T47D	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.3585530095996337	[249]	[125,96,132,98]	-9	hSpCas9	negative selection	8834503
46695587	46695610	16	+	27260156	T47D	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.0065524586679359675	[742]	[882,808,804,957]	0	hSpCas9	negative selection	8834504
46692486	46692509	16	-	27260156	T47D	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.7071498651511996	[976]	[321,405,346,312]	-9	hSpCas9	negative selection	8898757
46693111	46693134	16	-	27260156	T47D	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.08617692444177172	[666]	[778,876,826,810]	1	hSpCas9	negative selection	8898758
46695638	46695661	16	+	27260156	T47D	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.3415613627436793	[181]	[183,125,123,241]	-6	hSpCas9	negative selection	8898759
46691033	46691056	16	+	27260156	SU8686	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.4270752981244252	[295]	[93,69,116,171]	-9	hSpCas9	negative selection	8955753
46691036	46691059	16	-	27260156	SU8686	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.3269047946217758	[249]	[92,147,73,67]	-9	hSpCas9	negative selection	8955754
46695587	46695610	16	+	27260156	SU8686	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.2090639375983931	[742]	[632,579,585,773]	-4	hSpCas9	negative selection	8955755
46692486	46692509	16	-	27260156	SU8686	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.7690910040652494	[976]	[273,270,303,289]	-9	hSpCas9	negative selection	9020008
46693111	46693134	16	-	27260156	SU8686	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	-0.028081500002463622	[666]	[505,615,597,934]	0	hSpCas9	negative selection	9020009
46695638	46695661	16	+	27260156	SU8686	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-1.3945057525946898	[181]	[102,77,32,50]	-9	hSpCas9	negative selection	9020010
46691033	46691056	16	+	27260156	SKES1	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-1.0793698817545998	[295]	[104,112,193,136]	-9	hSpCas9	negative selection	9077004
46691036	46691059	16	-	27260156	SKES1	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.8265082363207789	[249]	[159,140,80,177]	-9	hSpCas9	negative selection	9077005
46695587	46695610	16	+	27260156	SKES1	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	0.004203735970580991	[742]	[855,917,659,587]	0	hSpCas9	negative selection	9077006
46692486	46692509	16	-	27260156	SKES1	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.7848240441813032	[976]	[240,340,256,289]	-9	hSpCas9	negative selection	9141259
46693111	46693134	16	-	27260156	SKES1	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.13508544190292837	[666]	[809,737,785,606]	3	hSpCas9	negative selection	9141260
46695638	46695661	16	+	27260156	SKES1	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.5612158412353032	[181]	[146,174,135,50]	-8	hSpCas9	negative selection	9141261
46691033	46691056	16	+	27260156	TOV112D	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.5986234719603298	[295]	[210,221,142,213]	-8	hSpCas9	negative selection	9198255
46691036	46691059	16	-	27260156	TOV112D	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.5756732455344373	[249]	[132,43,99,53]	-9	hSpCas9	negative selection	9198256
46695587	46695610	16	+	27260156	TOV112D	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.5213409737734455	[742]	[667,510,430,474]	-8	hSpCas9	negative selection	9198257
46692486	46692509	16	-	27260156	TOV112D	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.386731487990728	[976]	[424,324,385,352]	-9	hSpCas9	negative selection	9262510
46693111	46693134	16	-	27260156	TOV112D	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.3185762570719012	[666]	[878,1188,684,673]	6	hSpCas9	negative selection	9262511
46695638	46695661	16	+	27260156	TOV112D	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.714081039300793	[181]	[69,229,55,113]	-8	hSpCas9	negative selection	9262512
46691033	46691056	16	+	27260156	TC71	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.3929070178328258	[295]	[233,178,294,257]	-8	hSpCas9	negative selection	9319506
46691036	46691059	16	-	27260156	TC71	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.7621153131370623	[249]	[183,162,131,152]	-9	hSpCas9	negative selection	9319507
46695587	46695610	16	+	27260156	TC71	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.2325526387920836	[742]	[692,696,586,740]	-6	hSpCas9	negative selection	9319508
46692486	46692509	16	-	27260156	TC71	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.3720719581792593	[976]	[345,422,358,498]	-9	hSpCas9	negative selection	9383761
46693111	46693134	16	-	27260156	TC71	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	-0.06400570022045177	[666]	[602,697,644,799]	-2	hSpCas9	negative selection	9383762
46695638	46695661	16	+	27260156	TC71	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.4850195350402102	[181]	[129,119,145,162]	-8	hSpCas9	negative selection	9383763
46691033	46691056	16	+	27260156	TC32	viability	CGGCCTCTCCGCACGCACCACGG	ORC6	ENSG00000091651	-0.480662481168602	[295]	[202,174,260,162]	-7	hSpCas9	negative selection	9440757
46691036	46691059	16	-	27260156	TC32	viability	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.8755287643527759	[249]	[105,67,183,185]	-9	hSpCas9	negative selection	9440758
46695587	46695610	16	+	27260156	TC32	viability	AACAAAATGGTAGCCACATCCGG	ORC6	ENSG00000091651	-0.21017122747341677	[742]	[580,480,716,670]	-4	hSpCas9	negative selection	9440759
46692486	46692509	16	-	27260156	TC32	viability	TACAGCTAAACTGTACAGCTAGG	ORC6	ENSG00000091651	-1.1130853764089195	[976]	[362,342,550,478]	-9	hSpCas9	negative selection	9505012
46693111	46693134	16	-	27260156	TC32	viability	CAAGATCCACTTGCTGTGTCTGG	ORC6	ENSG00000091651	0.25081484795669673	[666]	[844,581,710,846]	4	hSpCas9	negative selection	9505013
46695638	46695661	16	+	27260156	TC32	viability	TGTAAACAACTAGAGAAGATTGG	ORC6	ENSG00000091651	-0.6045317295702313	[181]	[123,53,191,107]	-8	hSpCas9	negative selection	9505014
46689687	46689710	16	+	27869803	HPAFII	viability after 27 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	0.5233869957392505	[489]	[504,257,NaN]	4	hSpCas9	negative selection	9557188
46689747	46689770	16	-	27869803	HPAFII	viability after 27 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-3.8574737427066976	[390]	[17,10,NaN]	-9	hSpCas9	negative selection	9557189
46691036	46691059	16	-	27869803	HPAFII	viability after 27 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.1260218117652863	[333]	[146,24,NaN]	-6	hSpCas9	negative selection	9557190
46691108	46691131	16	-	27869803	HPAFII	viability after 27 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-3.5460650234812947	[203]	[18,0,NaN]	-9	hSpCas9	negative selection	9557191
46696026	46696049	16	+	27869803	HPAFII	viability after 27 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	0.633768199669737	[260]	[303,136,NaN]	5	hSpCas9	negative selection	9557192
46697549	46697572	16	+	27869803	HPAFII	viability after 27 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.9803757222523631	[199]	[285,141,NaN]	7	hSpCas9	negative selection	9557193
46689687	46689710	16	+	27869803	HPAFII	viability after 15 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	0.7057804329748041	[489]	[1321,570,NaN]	7	hSpCas9	negative selection	9639637
46689747	46689770	16	-	27869803	HPAFII	viability after 15 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.5900922910542128	[390]	[236,78,NaN]	-8	hSpCas9	negative selection	9639638
46691036	46691059	16	-	27869803	HPAFII	viability after 15 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.9407977470529311	[333]	[342,89,NaN]	-7	hSpCas9	negative selection	9639639
46691108	46691131	16	-	27869803	HPAFII	viability after 15 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-3.075763849278788	[203]	[62,2,NaN]	-9	hSpCas9	negative selection	9639640
46696026	46696049	16	+	27869803	HPAFII	viability after 15 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	0.460107835893193	[260]	[642,225,NaN]	5	hSpCas9	negative selection	9639641
46697549	46697572	16	+	27869803	HPAFII	viability after 15 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	1.0241080512490832	[199]	[639,310,NaN]	9	hSpCas9	negative selection	9639642
46689687	46689710	16	+	27869803	ASPC1	viability after 36 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	0.21888606674913635	[1334]	[988,572,198]	2	hSpCas9	negative selection	9722086
46689747	46689770	16	-	27869803	ASPC1	viability after 36 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-2.5579130927641023	[1065]	[39,135,20]	-9	hSpCas9	negative selection	9722087
46691036	46691059	16	-	27869803	ASPC1	viability after 36 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.5123315473977148	[798]	[34,65,165]	-8	hSpCas9	negative selection	9722088
46691108	46691131	16	-	27869803	ASPC1	viability after 36 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-2.2449251013521687	[715]	[121,26,23]	-9	hSpCas9	negative selection	9722089
46696026	46696049	16	+	27869803	ASPC1	viability after 36 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.22791209631540854	[787]	[184,349,175]	-2	hSpCas9	negative selection	9722090
46697549	46697572	16	+	27869803	ASPC1	viability after 36 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.8413807647985894	[545]	[730,136,226]	7	hSpCas9	negative selection	9722091
46689687	46689710	16	+	27869803	PATU8988S	viability after 35 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-0.562364762578378	[1262]	[330,357,NaN]	-5	hSpCas9	negative selection	9804535
46689747	46689770	16	-	27869803	PATU8988S	viability after 35 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.550375701824514	[811]	[179,42,NaN]	-8	hSpCas9	negative selection	9804536
46691036	46691059	16	-	27869803	PATU8988S	viability after 35 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-0.9735592717629387	[772]	[176,139,NaN]	-7	hSpCas9	negative selection	9804537
46691108	46691131	16	-	27869803	PATU8988S	viability after 35 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-5.156237659637209	[620]	[12,0,NaN]	-9	hSpCas9	negative selection	9804538
46696026	46696049	16	+	27869803	PATU8988S	viability after 35 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-1.3283719368599074	[747]	[104,134,NaN]	-8	hSpCas9	negative selection	9804539
46697549	46697572	16	+	27869803	PATU8988S	viability after 35 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	-0.12709469137299886	[547]	[243,159,NaN]	-1	hSpCas9	negative selection	9804540
46689687	46689710	16	+	27869803	PATU8988S	viability after 31 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	-0.5832702461360144	[1262]	[219,483,NaN]	-6	hSpCas9	negative selection	9886984
46689747	46689770	16	-	27869803	PATU8988S	viability after 31 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-1.2324081598048013	[811]	[150,120,NaN]	-8	hSpCas9	negative selection	9886985
46691036	46691059	16	-	27869803	PATU8988S	viability after 31 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.6165616063287698	[772]	[85,118,NaN]	-8	hSpCas9	negative selection	9886986
46691108	46691131	16	-	27869803	PATU8988S	viability after 31 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-5.111821656467761	[620]	[11,0,NaN]	-9	hSpCas9	negative selection	9886987
46696026	46696049	16	+	27869803	PATU8988S	viability after 31 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-1.0402249087480833	[747]	[93,209,NaN]	-8	hSpCas9	negative selection	9886988
46697549	46697572	16	+	27869803	PATU8988S	viability after 31 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.2399159398688256	[547]	[283,224,NaN]	3	hSpCas9	negative selection	9886989
46689687	46689710	16	+	27869803	HPAFII	viability after 35 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	0.42155454956697214	[489]	[470,175,NaN]	2	hSpCas9	negative selection	9969433
46689747	46689770	16	-	27869803	HPAFII	viability after 35 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-3.5968632857746963	[390]	[29,0,NaN]	-9	hSpCas9	negative selection	9969434
46691036	46691059	16	-	27869803	HPAFII	viability after 35 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.5083801679283297	[333]	[105,6,NaN]	-7	hSpCas9	negative selection	9969435
46691108	46691131	16	-	27869803	HPAFII	viability after 35 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-3.155169007912175	[203]	[20,0,NaN]	-8	hSpCas9	negative selection	9969436
46696026	46696049	16	+	27869803	HPAFII	viability after 35 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	0.41736765640672535	[260]	[151,203,NaN]	2	hSpCas9	negative selection	9969437
46697549	46697572	16	+	27869803	HPAFII	viability after 35 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.6607662058168204	[199]	[176,140,NaN]	4	hSpCas9	negative selection	9969438
46689687	46689710	16	+	27869803	HPAFII	viability after 31 days	TCGCTTTAGTGCCGGCGCCATGG	ORC6	ENSG00000091651	0.6209060108141264	[489]	[576,254,NaN]	4	hSpCas9	negative selection	10051882
46689747	46689770	16	-	27869803	HPAFII	viability after 31 days	TCAGCATGTCGGGCTCGGCGAGG	ORC6	ENSG00000091651	-3.3799484091450536	[390]	[33,6,NaN]	-9	hSpCas9	negative selection	10051883
46691036	46691059	16	-	27869803	HPAFII	viability after 31 days	TCTCCGTGGTGCGTGCGGAGAGG	ORC6	ENSG00000091651	-1.4421073615711055	[333]	[90,44,NaN]	-7	hSpCas9	negative selection	10051884
46691108	46691131	16	-	27869803	HPAFII	viability after 31 days	ACCTACTTACCCTGTCCAAGGGG	ORC6	ENSG00000091651	-3.698041832769164	[203]	[15,0,NaN]	-9	hSpCas9	negative selection	10051885
46696026	46696049	16	+	27869803	HPAFII	viability after 31 days	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	0.4460716717292826	[260]	[222,173,NaN]	3	hSpCas9	negative selection	10051886
46697549	46697572	16	+	27869803	HPAFII	viability after 31 days	AAATGCTGCCAGTGCTCAAAAGG	ORC6	ENSG00000091651	0.9190872015667477	[199]	[239,181,NaN]	7	hSpCas9	negative selection	10051887
46691017	46691040	16	-	28162770	P31FUJ	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-3.446927009767226	[463]	[49]	-9	hSpCas9	negative selection	10205057
46696045	46696068	16	+	28162770	P31FUJ	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-1.7486803932000499	[631]	[220]	-8	hSpCas9	negative selection	10205058
46696026	46696049	16	+	28162770	P31FUJ	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-1.8407015164126936	[316]	[103]	-8	hSpCas9	negative selection	10205059
46696074	46696097	16	-	28162770	P31FUJ	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	-0.6113138276681085	[285]	[219]	-5	hSpCas9	negative selection	10205060
46693145	46693168	16	-	28162770	P31FUJ	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-2.3331527297468475	[252]	[58]	-8	hSpCas9	negative selection	10205061
46696063	46696086	16	+	28162770	P31FUJ	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-0.38202821318885477	[345]	[311]	-3	hSpCas9	negative selection	10205062
46689749	46689772	16	+	28162770	P31FUJ	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-0.8613539736832178	[251]	[162]	-6	hSpCas9	negative selection	10205063
46691099	46691122	16	+	28162770	P31FUJ	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-2.6383169295747155	[301]	[56]	-9	hSpCas9	negative selection	10205064
46689693	46689716	16	+	28162770	P31FUJ	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-1.5688514075463937	[153]	[60]	-7	hSpCas9	negative selection	10205065
46690979	46691002	16	+	28162770	P31FUJ	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-3.9552682288854695	[131]	[9]	-9	hSpCas9	negative selection	10205066
46691017	46691040	16	-	28162770	TF1	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10374423
46696045	46696068	16	+	28162770	TF1	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	NaN	[NaN]	[359]	1	hSpCas9	negative selection	10374424
46696026	46696049	16	+	28162770	TF1	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	NaN	[NaN]	[155]	1	hSpCas9	negative selection	10374425
46696074	46696097	16	-	28162770	TF1	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	NaN	[NaN]	[355]	1	hSpCas9	negative selection	10374426
46693145	46693168	16	-	28162770	TF1	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	NaN	[NaN]	[40]	1	hSpCas9	negative selection	10374427
46696063	46696086	16	+	28162770	TF1	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	NaN	[NaN]	[342]	1	hSpCas9	negative selection	10374428
46689749	46689772	16	+	28162770	TF1	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	NaN	[NaN]	[174]	1	hSpCas9	negative selection	10374429
46691099	46691122	16	+	28162770	TF1	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	NaN	[NaN]	[19]	1	hSpCas9	negative selection	10374430
46689693	46689716	16	+	28162770	TF1	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10374431
46690979	46691002	16	+	28162770	TF1	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	NaN	[NaN]	[72]	1	hSpCas9	negative selection	10374432
46691017	46691040	16	-	28162770	SKM1	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-3.0887882387169068	[153]	[31]	-9	hSpCas9	negative selection	10543789
46696045	46696068	16	+	28162770	SKM1	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-1.5979614238040756	[124]	[72]	-8	hSpCas9	negative selection	10543790
46696026	46696049	16	+	28162770	SKM1	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.8403802273368602	[78]	[77]	-6	hSpCas9	negative selection	10543791
46696074	46696097	16	-	28162770	SKM1	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	0.7572244331500063	[83]	[250]	7	hSpCas9	negative selection	10543792
46693145	46693168	16	-	28162770	SKM1	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-3.8220016980220057	[87]	[10]	-9	hSpCas9	negative selection	10543793
46696063	46696086	16	+	28162770	SKM1	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-0.8875900396495824	[89]	[85]	-6	hSpCas9	negative selection	10543794
46689749	46689772	16	+	28162770	SKM1	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-1.8825432399570563	[72]	[34]	-8	hSpCas9	negative selection	10543795
46691099	46691122	16	+	28162770	SKM1	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-4.649820722639325	[70]	[4]	-9	hSpCas9	negative selection	10543796
46689693	46689716	16	+	28162770	SKM1	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-3.8220016980220053	[31]	[3]	-9	hSpCas9	negative selection	10543797
46690979	46691002	16	+	28162770	SKM1	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-0.8663958173804588	[32]	[31]	-6	hSpCas9	negative selection	10543798
46691017	46691040	16	-	28162770	SKM1	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-3.0887882387169068	[153]	[31]	-9	hSpCas9	negative selection	10713155
46696045	46696068	16	+	28162770	SKM1	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-1.5979614238040756	[124]	[72]	-8	hSpCas9	negative selection	10713156
46696026	46696049	16	+	28162770	SKM1	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.8403802273368602	[78]	[77]	-6	hSpCas9	negative selection	10713157
46696074	46696097	16	-	28162770	SKM1	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	0.7572244331500063	[83]	[250]	7	hSpCas9	negative selection	10713158
46693145	46693168	16	-	28162770	SKM1	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-3.8220016980220057	[87]	[10]	-9	hSpCas9	negative selection	10713159
46696063	46696086	16	+	28162770	SKM1	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-0.8875900396495824	[89]	[85]	-6	hSpCas9	negative selection	10713160
46689749	46689772	16	+	28162770	SKM1	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-1.8825432399570563	[72]	[34]	-8	hSpCas9	negative selection	10713161
46691099	46691122	16	+	28162770	SKM1	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-4.649820722639325	[70]	[4]	-9	hSpCas9	negative selection	10713162
46689693	46689716	16	+	28162770	SKM1	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-3.8220016980220053	[31]	[3]	-9	hSpCas9	negative selection	10713163
46690979	46691002	16	+	28162770	SKM1	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-0.8663958173804588	[32]	[31]	-6	hSpCas9	negative selection	10713164
46691017	46691040	16	-	28162770	PL21	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-1.7043444834121033	[598]	[79]	-8	hSpCas9	negative selection	10882521
46696045	46696068	16	+	28162770	PL21	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-1.4112950975930274	[439]	[71]	-7	hSpCas9	negative selection	10882522
46696026	46696049	16	+	28162770	PL21	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.514883426796209	[347]	[105]	-4	hSpCas9	negative selection	10882523
46696074	46696097	16	-	28162770	PL21	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	-0.16974951884921063	[366]	[141]	-1	hSpCas9	negative selection	10882524
46693145	46693168	16	-	28162770	PL21	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-4.4769927301597034	[306]	[5]	-9	hSpCas9	negative selection	10882525
46696063	46696086	16	+	28162770	PL21	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-0.8782314490635519	[434]	[102]	-6	hSpCas9	negative selection	10882526
46689749	46689772	16	+	28162770	PL21	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-1.2058527451865166	[211]	[39]	-7	hSpCas9	negative selection	10882527
46691099	46691122	16	+	28162770	PL21	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-1.0959098485724368	[220]	[44]	-6	hSpCas9	negative selection	10882528
46689693	46689716	16	+	28162770	PL21	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	1.1305986812362432	[84]	[80]	8	hSpCas9	negative selection	10882529
46690979	46691002	16	+	28162770	PL21	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-0.3234223415676927	[68]	[23]	-2	hSpCas9	negative selection	10882530
46691017	46691040	16	-	28162770	P31FUJ	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-3.446927009767226	[463]	[49]	-9	hSpCas9	negative selection	11051887
46696045	46696068	16	+	28162770	P31FUJ	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-1.7486803932000499	[631]	[220]	-8	hSpCas9	negative selection	11051888
46696026	46696049	16	+	28162770	P31FUJ	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-1.8407015164126936	[316]	[103]	-8	hSpCas9	negative selection	11051889
46696074	46696097	16	-	28162770	P31FUJ	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	-0.6113138276681085	[285]	[219]	-5	hSpCas9	negative selection	11051890
46693145	46693168	16	-	28162770	P31FUJ	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-2.3331527297468475	[252]	[58]	-8	hSpCas9	negative selection	11051891
46696063	46696086	16	+	28162770	P31FUJ	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-0.38202821318885477	[345]	[311]	-3	hSpCas9	negative selection	11051892
46689749	46689772	16	+	28162770	P31FUJ	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-0.8613539736832178	[251]	[162]	-6	hSpCas9	negative selection	11051893
46691099	46691122	16	+	28162770	P31FUJ	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-2.6383169295747155	[301]	[56]	-9	hSpCas9	negative selection	11051894
46689693	46689716	16	+	28162770	P31FUJ	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-1.5688514075463937	[153]	[60]	-7	hSpCas9	negative selection	11051895
46690979	46691002	16	+	28162770	P31FUJ	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-3.9552682288854695	[131]	[9]	-9	hSpCas9	negative selection	11051896
46691017	46691040	16	-	28162770	OCIAML5	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.6391728090777953	[282]	[81]	-8	hSpCas9	negative selection	11221253
46696045	46696068	16	+	28162770	OCIAML5	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-1.8907989653527115	[301]	[146]	-7	hSpCas9	negative selection	11221254
46696026	46696049	16	+	28162770	OCIAML5	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-1.4119380906223227	[170]	[115]	-7	hSpCas9	negative selection	11221255
46696074	46696097	16	-	28162770	OCIAML5	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	-0.8156941811990353	[234]	[240]	-5	hSpCas9	negative selection	11221256
46693145	46693168	16	-	28162770	OCIAML5	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-5.311498189501295	[197]	[8]	-9	hSpCas9	negative selection	11221257
46696063	46696086	16	+	28162770	OCIAML5	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-1.5849625007211563	[235]	[141]	-7	hSpCas9	negative selection	11221258
46689749	46689772	16	+	28162770	OCIAML5	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-0.15162685272290488	[95]	[155]	-1	hSpCas9	negative selection	11221259
46691099	46691122	16	+	28162770	OCIAML5	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-8.051738915700362	[146]	[0]	-9	hSpCas9	negative selection	11221260
46689693	46689716	16	+	28162770	OCIAML5	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-4.953604597326059	[102]	[5]	-9	hSpCas9	negative selection	11221261
46690979	46691002	16	+	28162770	OCIAML5	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-2.2592419523698704	[60]	[22]	-8	hSpCas9	negative selection	11221262
46691017	46691040	16	-	28162770	EOL1	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.6936217745405404	[834]	[67]	-9	hSpCas9	negative selection	11390619
46696045	46696068	16	+	28162770	EOL1	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-2.1945634403171406	[529]	[60]	-8	hSpCas9	negative selection	11390620
46696026	46696049	16	+	28162770	EOL1	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.9927033356437056	[558]	[147]	-6	hSpCas9	negative selection	11390621
46696074	46696097	16	-	28162770	EOL1	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	-1.4377232106759843	[688]	[133]	-7	hSpCas9	negative selection	11390622
46693145	46693168	16	-	28162770	EOL1	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-4.724545066570338	[551]	[10]	-9	hSpCas9	negative selection	11390623
46696063	46696086	16	+	28162770	EOL1	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	0.2738559515463206	[594]	[378]	2	hSpCas9	negative selection	11390624
46689749	46689772	16	+	28162770	EOL1	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-0.7962981572323946	[266]	[80]	-5	hSpCas9	negative selection	11390625
46691099	46691122	16	+	28162770	EOL1	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-2.009863886801889	[343]	[44]	-8	hSpCas9	negative selection	11390626
46689693	46689716	16	+	28162770	EOL1	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-2.162915069679805	[118]	[13]	-8	hSpCas9	negative selection	11390627
46690979	46691002	16	+	28162770	EOL1	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-1.560879055599707	[83]	[14]	-7	hSpCas9	negative selection	11390628
46691017	46691040	16	-	28162770	MOLM13	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-3.1395481519323964	[840]	[68]	-8	hSpCas9	negative selection	11559985
46696045	46696068	16	+	28162770	MOLM13	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-2.78605187566669	[600]	[62]	-8	hSpCas9	negative selection	11559986
46696026	46696049	16	+	28162770	MOLM13	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.2809993799974467	[404]	[240]	-2	hSpCas9	negative selection	11559987
46696074	46696097	16	-	28162770	MOLM13	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	-2.353707463088804	[508]	[71]	-8	hSpCas9	negative selection	11559988
46693145	46693168	16	-	28162770	MOLM13	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-5.006369654770358	[488]	[10]	-9	hSpCas9	negative selection	11559989
46696063	46696086	16	+	28162770	MOLM13	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-1.7268222990157556	[498]	[108]	-7	hSpCas9	negative selection	11559990
46689749	46689772	16	+	28162770	MOLM13	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-2.1643788339549337	[433]	[69]	-7	hSpCas9	negative selection	11559991
46691099	46691122	16	+	28162770	MOLM13	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-1.8038193578550485	[366]	[75]	-7	hSpCas9	negative selection	11559992
46689693	46689716	16	+	28162770	MOLM13	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-2.979569595426643	[119]	[10]	-8	hSpCas9	negative selection	11559993
46690979	46691002	16	+	28162770	MOLM13	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-6.941501554593123	[169]	[0]	-9	hSpCas9	negative selection	11559994
46691017	46691040	16	-	28162770	HEL	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.8733618105759953	[674]	[58]	-8	hSpCas9	negative selection	11729351
46696045	46696068	16	+	28162770	HEL	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-0.7865405898542658	[508]	[188]	-5	hSpCas9	negative selection	11729352
46696026	46696049	16	+	28162770	HEL	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	1.073509257543797	[341]	[460]	8	hSpCas9	negative selection	11729353
46696074	46696097	16	-	28162770	HEL	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	-0.4061707684805894	[479]	[231]	-3	hSpCas9	negative selection	11729354
46693145	46693168	16	-	28162770	HEL	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-4.608980260605603	[380]	[9]	-9	hSpCas9	negative selection	11729355
46696063	46696086	16	+	28162770	HEL	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	0.11004364089617402	[514]	[355]	0	hSpCas9	negative selection	11729356
46689749	46689772	16	+	28162770	HEL	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	0.09254174943987759	[245]	[167]	0	hSpCas9	negative selection	11729357
46691099	46691122	16	+	28162770	HEL	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-3.755292241972797	[252]	[11]	-9	hSpCas9	negative selection	11729358
46689693	46689716	16	+	28162770	HEL	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-2.8912397400019945	[138]	[11]	-8	hSpCas9	negative selection	11729359
46690979	46691002	16	+	28162770	HEL	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-5.33454109149956	[125]	[1]	-9	hSpCas9	negative selection	11729360
46691017	46691040	16	-	28162770	MV411	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-3.749827481495986	[526]	[32]	-9	hSpCas9	negative selection	11898717
46696045	46696068	16	+	28162770	MV411	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-3.04534419844507	[440]	[44]	-9	hSpCas9	negative selection	11898718
46696026	46696049	16	+	28162770	MV411	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-1.233689138953841	[334]	[119]	-7	hSpCas9	negative selection	11898719
46696074	46696097	16	-	28162770	MV411	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	-1.2085078920762746	[309]	[112]	-7	hSpCas9	negative selection	11898720
46693145	46693168	16	-	28162770	MV411	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-3.0744905441045867	[289]	[28]	-9	hSpCas9	negative selection	11898721
46696063	46696086	16	+	28162770	MV411	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-1.0237095008383383	[320]	[132]	-6	hSpCas9	negative selection	11898722
46689749	46689772	16	+	28162770	MV411	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-1.1310740724709545	[207]	[79]	-6	hSpCas9	negative selection	11898723
46691099	46691122	16	+	28162770	MV411	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-3.635205498579066	[235]	[15]	-9	hSpCas9	negative selection	11898724
46689693	46689716	16	+	28162770	MV411	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-2.659453044825743	[89]	[11]	-9	hSpCas9	negative selection	11898725
46690979	46691002	16	+	28162770	MV411	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-1.3089557977416098	[99]	[33]	-7	hSpCas9	negative selection	11898726
46691017	46691040	16	-	28162770	MONOMAC1	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-3.3954504054615615	[357]	[38]	-9	hSpCas9	negative selection	12068083
46696045	46696068	16	+	28162770	MONOMAC1	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-1.6537893655009697	[268]	[97]	-8	hSpCas9	negative selection	12068084
46696026	46696049	16	+	28162770	MONOMAC1	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-1.6439232123777374	[228]	[83]	-8	hSpCas9	negative selection	12068085
46696074	46696097	16	-	28162770	MONOMAC1	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	-0.8008583750320256	[230]	[151]	-6	hSpCas9	negative selection	12068086
46693145	46693168	16	-	28162770	MONOMAC1	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-4.425855537555435	[224]	[11]	-9	hSpCas9	negative selection	12068087
46696063	46696086	16	+	28162770	MONOMAC1	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-2.272701116991626	[273]	[64]	-9	hSpCas9	negative selection	12068088
46689749	46689772	16	+	28162770	MONOMAC1	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-2.736770093787712	[156]	[26]	-9	hSpCas9	negative selection	12068089
46691099	46691122	16	+	28162770	MONOMAC1	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-2.3424672865811176	[145]	[32]	-9	hSpCas9	negative selection	12068090
46689693	46689716	16	+	28162770	MONOMAC1	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-3.4771447662522887	[67]	[6]	-9	hSpCas9	negative selection	12068091
46690979	46691002	16	+	28162770	MONOMAC1	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-2.9132438810589623	[45]	[6]	-9	hSpCas9	negative selection	12068092
46691017	46691040	16	-	28162770	OCIAML2	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.87116775482589	[98]	[74]	-9	hSpCas9	negative selection	12237449
46696045	46696068	16	+	28162770	OCIAML2	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	-0.9200188293117817	[84]	[248]	-6	hSpCas9	negative selection	12237450
46696026	46696049	16	+	28162770	OCIAML2	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-1.3096379485698564	[71]	[160]	-7	hSpCas9	negative selection	12237451
46696074	46696097	16	-	28162770	OCIAML2	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	-0.31075848846377174	[63]	[285]	-3	hSpCas9	negative selection	12237452
46693145	46693168	16	-	28162770	OCIAML2	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-3.5295235142957297	[49]	[23]	-9	hSpCas9	negative selection	12237453
46696063	46696086	16	+	28162770	OCIAML2	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-0.7336642310759552	[62]	[209]	-5	hSpCas9	negative selection	12237454
46689749	46689772	16	+	28162770	OCIAML2	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-0.5576131268368011	[46]	[176]	-4	hSpCas9	negative selection	12237455
46691099	46691122	16	+	28162770	OCIAML2	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-2.261176459613212	[31]	[36]	-8	hSpCas9	negative selection	12237456
46689693	46689716	16	+	28162770	OCIAML2	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-2.6226329186872115	[9]	[8]	-8	hSpCas9	negative selection	12237457
46690979	46691002	16	+	28162770	OCIAML2	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-2.0921182019884315	[9]	[12]	-8	hSpCas9	negative selection	12237458
46691017	46691040	16	-	28162770	OCIAML3	viability	GAGGCCGACACACTTCACCCGGG	ORC6	ENSG00000091651	-2.9885394841683652	[162]	[61]	-9	hSpCas9	negative selection	12406815
46696045	46696068	16	+	28162770	OCIAML3	viability	ACGGAAGAGAAAGAAGATAGTGG	ORC6	ENSG00000091651	0.09699649780731767	[117]	[380]	0	hSpCas9	negative selection	12406816
46696026	46696049	16	+	28162770	OCIAML3	viability	GAGATGTAGCTACTCCACCACGG	ORC6	ENSG00000091651	-0.2643021948450814	[73]	[185]	-2	hSpCas9	negative selection	12406817
46696074	46696097	16	-	28162770	OCIAML3	viability	GTAAAACTTACCCTTTGCTGGGG	ORC6	ENSG00000091651	0.058744949938957736	[96]	[304]	0	hSpCas9	negative selection	12406818
46693145	46693168	16	-	28162770	OCIAML3	viability	AGTGCAGCAGAAGTGAAAAGTGG	ORC6	ENSG00000091651	-2.709484857744099	[90]	[41]	-9	hSpCas9	negative selection	12406819
46696063	46696086	16	+	28162770	OCIAML3	viability	AGTGGTTGAAGCCCCAGCAAAGG	ORC6	ENSG00000091651	-1.214661848188628	[132]	[172]	-7	hSpCas9	negative selection	12406820
46689749	46689772	16	+	28162770	OCIAML3	viability	TCGCCGAGCCCGACATGCTGAGG	ORC6	ENSG00000091651	-1.2868261308059874	[58]	[72]	-7	hSpCas9	negative selection	12406821
46691099	46691122	16	+	28162770	OCIAML3	viability	GATGAAGTGCCCCTTGGACAGGG	ORC6	ENSG00000091651	-2.47270134410203	[56]	[30]	-9	hSpCas9	negative selection	12406822
46689693	46689716	16	+	28162770	OCIAML3	viability	TAGTGCCGGCGCCATGGGGTCGG	ORC6	ENSG00000091651	-0.6398113299372878	[31]	[61]	-5	hSpCas9	negative selection	12406823
46690979	46691002	16	+	28162770	OCIAML3	viability	CCTTTTAACCAGGAAAGCAGAGG	ORC6	ENSG00000091651	-4.915935735211526	[19]	[1]	-9	hSpCas9	negative selection	12406824