Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5000
• Symbol: Orc4
• Description: origin recognition complex subunit 4

DataSource: http://genomecrispr.dkfz.de/#!/results/Orc4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
147943438	147943461	2	+	26472758	Jiyoye	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	2.1157125673455623	[40]	[133]	9	hSpCas9	negative selection	114051
147972774	147972797	2	+	26472758	Jiyoye	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-1.5093012629318432	[150]	[39]	-7	hSpCas9	negative selection	114052
147948082	147948105	2	+	26472758	Jiyoye	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	-0.7283395891506078	[144]	[65]	-5	hSpCas9	negative selection	114053
147939193	147939216	2	+	26472758	Jiyoye	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.2551722880608236	[59]	[53]	2	hSpCas9	negative selection	114054
147935537	147935560	2	-	26472758	Jiyoye	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-0.2653935479293774	[313]	[196]	-2	hSpCas9	negative selection	114055
147935516	147935539	2	-	26472758	Jiyoye	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	5.2651563766334455	[0]	[28]	9	hSpCas9	negative selection	114056
147935543	147935566	2	-	26472758	Jiyoye	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	0.17687776208407913	[60]	[51]	1	hSpCas9	negative selection	114057
147935535	147935558	2	+	26472758	Jiyoye	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	0.8101400484841421	[89]	[118]	5	hSpCas9	negative selection	114058
147972755	147972778	2	-	26472758	Jiyoye	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-2.2787160280660634	[147]	[22]	-8	hSpCas9	negative selection	114059
147972791	147972814	2	-	26472758	Jiyoye	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-1.3884661199879402	[183]	[52]	-7	hSpCas9	negative selection	114060
147943438	147943461	2	+	26472758	KBM7	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.1810392414412897	[750,614]	[368,355]	1	hSpCas9	negative selection	305169
147972774	147972797	2	+	26472758	KBM7	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-0.38938004996159004	[402,283]	[126,116]	-4	hSpCas9	negative selection	305170
147948082	147948105	2	+	26472758	KBM7	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	-0.2642011627318087	[635,700]	[371,167]	-3	hSpCas9	negative selection	305171
147939193	147939216	2	+	26472758	KBM7	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.13951216133042132	[299,327]	[179,149]	1	hSpCas9	negative selection	305172
147935537	147935560	2	-	26472758	KBM7	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-1.128467812078786	[2040,1451]	[333,403]	-7	hSpCas9	negative selection	305173
147935516	147935539	2	-	26472758	KBM7	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	-0.12126871538191586	[204,132]	[112,34]	-1	hSpCas9	negative selection	305174
147935543	147935566	2	-	26472758	KBM7	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-1.5765283014170137	[326,405]	[54,61]	-8	hSpCas9	negative selection	305175
147935535	147935558	2	+	26472758	KBM7	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	-0.3282021135926878	[880,1120]	[365,394]	-3	hSpCas9	negative selection	305176
147972755	147972778	2	-	26472758	KBM7	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-3.0328514851311867	[747,621]	[16,58]	-9	hSpCas9	negative selection	305177
147972791	147972814	2	-	26472758	KBM7	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-1.5292205659180753	[648,553]	[84,108]	-8	hSpCas9	negative selection	305178
147943438	147943461	2	+	26472758	Raji	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.2703463511821144	[368]	[70]	-2	hSpCas9	negative selection	496287
147972774	147972797	2	+	26472758	Raji	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	0.4917242374295268	[189]	[61]	5	hSpCas9	negative selection	496288
147948082	147948105	2	+	26472758	Raji	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	0.023146998205567537	[334]	[78]	0	hSpCas9	negative selection	496289
147939193	147939216	2	+	26472758	Raji	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-0.6088234986258093	[183]	[27]	-5	hSpCas9	negative selection	496290
147935537	147935560	2	-	26472758	Raji	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-0.3247598678983492	[706]	[130]	-3	hSpCas9	negative selection	496291
147935516	147935539	2	-	26472758	Raji	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	0.6479519167363024	[54]	[19]	6	hSpCas9	negative selection	496292
147935543	147935566	2	-	26472758	Raji	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-2.178018683488649	[194]	[9]	-8	hSpCas9	negative selection	496293
147935535	147935558	2	+	26472758	Raji	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	-0.45373222339318897	[359]	[60]	-4	hSpCas9	negative selection	496294
147972755	147972778	2	-	26472758	Raji	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-1.016512935024308	[400]	[45]	-6	hSpCas9	negative selection	496295
147972791	147972814	2	-	26472758	Raji	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-0.5543361643315946	[385]	[60]	-4	hSpCas9	negative selection	496296
147943438	147943461	2	+	26472758	K562	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.7386829180958657	[371]	[523]	6	hSpCas9	negative selection	687405
147972774	147972797	2	+	26472758	K562	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-0.5554675234873072	[288]	[165]	-3	hSpCas9	negative selection	687406
147948082	147948105	2	+	26472758	K562	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	-0.965666798218388	[427]	[184]	-5	hSpCas9	negative selection	687407
147939193	147939216	2	+	26472758	K562	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.1937926545964789	[347]	[335]	1	hSpCas9	negative selection	687408
147935537	147935560	2	-	26472758	K562	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	0.15562355289901664	[1624]	[1527]	1	hSpCas9	negative selection	687409
147935516	147935539	2	-	26472758	K562	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	1.0656532387302569	[132]	[234]	8	hSpCas9	negative selection	687410
147935543	147935566	2	-	26472758	K562	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-2.590770402587883	[313]	[43]	-8	hSpCas9	negative selection	687411
147935535	147935558	2	+	26472758	K562	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	-0.5893889897675707	[687]	[385]	-4	hSpCas9	negative selection	687412
147972755	147972778	2	-	26472758	K562	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-2.9154526091119424	[428]	[47]	-8	hSpCas9	negative selection	687413
147972791	147972814	2	-	26472758	K562	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-0.8546894173464776	[481]	[224]	-5	hSpCas9	negative selection	687414
147943438	147943461	2	+	26627737	DLD1	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-1.2029953580135797	[410]	[67,72,30]	-8	hSpCas9	negative selection	808795
147958337	147958360	2	-	26627737	DLD1	viability	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-2.2847229034654974	[193]	[17,11,7]	-9	hSpCas9	negative selection	808796
147943438	147943461	2	+	26627737	GBM cells	viability after 5 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.372477450770985	[156]	[123,93]	6	hSpCas9	negative selection	891110
147958337	147958360	2	-	26627737	GBM cells	viability after 5 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-0.3450117080004037	[179]	[76,74]	-5	hSpCas9	negative selection	891111
147943438	147943461	2	+	26627737	GBM cells	viability after 13 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.40766133710200825	[156]	[112,112]	5	hSpCas9	negative selection	973425
147958337	147958360	2	-	26627737	GBM cells	viability after 13 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-1.603135128329662	[179]	[51,15]	-9	hSpCas9	negative selection	973426
147943438	147943461	2	+	26627737	GBM cells	viability after 21 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.3679919911842863	[156]	[119,100]	4	hSpCas9	negative selection	1055740
147958337	147958360	2	-	26627737	GBM cells	viability after 21 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-2.484169937628004	[179]	[17,16]	-9	hSpCas9	negative selection	1055741
147943438	147943461	2	+	26627737	RPE1	viability after 9 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.031468891166823276	[444]	[134,137]	0	hSpCas9	negative selection	1138055
147958337	147958360	2	-	26627737	RPE1	viability after 9 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-3.6103072823982387	[866]	[9,37]	-9	hSpCas9	negative selection	1138056
147943438	147943461	2	+	26627737	RPE1	viability after 12 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.5801373595526736	[444]	[78,80]	-4	hSpCas9	negative selection	1220370
147958337	147958360	2	-	26627737	RPE1	viability after 12 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-6.843312668988982	[866]	[2,0]	-9	hSpCas9	negative selection	1220371
147943438	147943461	2	+	26627737	RPE1	viability after 15 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.45654323710528655	[444]	[162,22]	-3	hSpCas9	negative selection	1302685
147958337	147958360	2	-	26627737	RPE1	viability after 15 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-7.938139309349941	[866]	[0,0]	-9	hSpCas9	negative selection	1302686
147943438	147943461	2	+	26627737	RPE1	viability after 18 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-1.0813544189492976	[444]	[34,79]	-6	hSpCas9	negative selection	1385000
147958337	147958360	2	-	26627737	RPE1	viability after 18 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-7.870219923121092	[866]	[0,0]	-9	hSpCas9	negative selection	1385001
147943438	147943461	2	+	26627737	HeLa	viability after 8 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	1.035041459409972	[250]	[330,139,223]	7	hSpCas9	negative selection	1467315
147958337	147958360	2	-	26627737	HeLa	viability after 8 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	1.2894779107367196	[105]	[203,21,130]	8	hSpCas9	negative selection	1467316
147943438	147943461	2	+	26627737	HeLa	viability after 12 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.6798326401301403	[250]	[288,81,139]	5	hSpCas9	negative selection	1549630
147958337	147958360	2	-	26627737	HeLa	viability after 12 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-0.04278407792909378	[105]	[27,43,54]	0	hSpCas9	negative selection	1549631
147943438	147943461	2	+	26627737	HeLa	viability after 15 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	1.1127997310117999	[250]	[292,87,285]	7	hSpCas9	negative selection	1631945
147958337	147958360	2	-	26627737	HeLa	viability after 15 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-0.3298882365224993	[105]	[12,22,69]	-3	hSpCas9	negative selection	1631946
147943438	147943461	2	+	26627737	HeLa	viability after 18 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	1.044461948977465	[250]	[178,69,285]	7	hSpCas9	negative selection	1714260
147958337	147958360	2	-	26627737	HeLa	viability after 18 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-0.2864408807486436	[105]	[9,19,69]	-2	hSpCas9	negative selection	1714261
147943438	147943461	2	+	26627737	HCT116	viability after 6 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-1.056178488735364	[436]	[72,10]	-6	hSpCas9	negative selection	1796575
147958337	147958360	2	-	26627737	HCT116	viability after 6 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-1.114959017556445	[437]	[83,2]	-6	hSpCas9	negative selection	1796576
147943438	147943461	2	+	26627737	HCT116	viability after 8 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	1.2143439925457495	[115]	[221,136,87]	8	hSpCas9	negative selection	1878890
147958337	147958360	2	-	26627737	HCT116	viability after 8 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-0.05888246223193305	[154]	[123,62,59]	0	hSpCas9	negative selection	1878891
147943438	147943461	2	+	26627737	HCT116	viability after 9 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.03322467957919517	[436]	[43,178]	0	hSpCas9	negative selection	1961205
147958337	147958360	2	-	26627737	HCT116	viability after 9 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-2.6328565183421015	[437]	[24,13]	-9	hSpCas9	negative selection	1961206
147943438	147943461	2	+	26627737	HCT116	viability after 12 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.9569938283218515	[115]	[114,63,174]	7	hSpCas9	negative selection	2043520
147958337	147958360	2	-	26627737	HCT116	viability after 12 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-1.3400846385192697	[154]	[26,32,36]	-8	hSpCas9	negative selection	2043521
147943438	147943461	2	+	26627737	HCT116	viability after 15 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.5101891743136255	[115]	[74,93,112]	5	hSpCas9	negative selection	2125835
147958337	147958360	2	-	26627737	HCT116	viability after 15 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-1.6750107035731212	[154]	[14,33,32]	-9	hSpCas9	negative selection	2125836
147943438	147943461	2	+	26627737	HCT116	viability after 18 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	1.0263942561834065	[115]	[158,58,128]	7	hSpCas9	negative selection	2208150
147958337	147958360	2	-	26627737	HCT116	viability after 18 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-1.1492511530506555	[154]	[24,48,25]	-7	hSpCas9	negative selection	2208151
147948155	147948178	2	+	24336569	HL60	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.8566771641520656	[515]	[602]	-7	hSpCas9	negative selection	2282212
147952372	147952395	2	-	24336569	HL60	viability	TATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	0.050437786759644165	[1430]	[3135]	0	hSpCas9	negative selection	2282213
147952383	147952406	2	+	24336569	HL60	viability	GTAAGACCAATAACTGCTATTGG	ORC4	ENSG00000115947	0.36469913515596186	[853]	[2326]	3	hSpCas9	negative selection	2282214
147952432	147952455	2	+	24336569	HL60	viability	AAAGATTATAGAGAAGTGTTTGG	ORC4	ENSG00000115947	0.1038642260450112	[382]	[870]	1	hSpCas9	negative selection	2282215
147952482	147952505	2	+	24336569	HL60	viability	TCATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	0.3899401596744769	[479]	[1330]	3	hSpCas9	negative selection	2282216
147952498	147952521	2	+	24336569	HL60	viability	TCACTGGGCAACTGCTAGTTCGG	ORC4	ENSG00000115947	-0.3663676864232809	[903]	[1483]	-3	hSpCas9	negative selection	2282217
147955356	147955379	2	+	24336569	HL60	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	0.6637343453661383	[331]	[1112]	5	hSpCas9	negative selection	2282218
147958324	147958347	2	-	24336569	HL60	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	-0.16436718229156577	[1539]	[2907]	-1	hSpCas9	negative selection	2282219
147958334	147958357	2	+	24336569	HL60	viability	CTGCCTTGTGATTTCCTTTAGGG	ORC4	ENSG00000115947	1.8691478724089399	[51]	[401]	9	hSpCas9	negative selection	2282220
147958790	147958813	2	-	24336569	HL60	viability	GTATTACAAGTTCACTTAAATGG	ORC4	ENSG00000115947	0.6678664876535632	[394]	[1327]	6	hSpCas9	negative selection	2282221
147948155	147948178	2	+	24336569	KBM7	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.9111035698200628	[352]	[511]	-6	hSpCas9	negative selection	2349389
147952372	147952395	2	-	24336569	KBM7	viability	TATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	0.6002995392644885	[1014]	[4196]	5	hSpCas9	negative selection	2349390
147952383	147952406	2	+	24336569	KBM7	viability	GTAAGACCAATAACTGCTATTGG	ORC4	ENSG00000115947	0.5840664300675826	[619]	[2534]	5	hSpCas9	negative selection	2349391
147952432	147952455	2	+	24336569	KBM7	viability	AAAGATTATAGAGAAGTGTTTGG	ORC4	ENSG00000115947	0.5136884089624029	[301]	[1175]	5	hSpCas9	negative selection	2349392
147952482	147952505	2	+	24336569	KBM7	viability	TCATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	-0.11568293257028453	[374]	[943]	-1	hSpCas9	negative selection	2349393
147952498	147952521	2	+	24336569	KBM7	viability	TCACTGGGCAACTGCTAGTTCGG	ORC4	ENSG00000115947	0.200398446606615	[768]	[2409]	1	hSpCas9	negative selection	2349394
147955356	147955379	2	+	24336569	KBM7	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.9417869092613342	[411]	[584]	-6	hSpCas9	negative selection	2349395
147958324	147958347	2	-	24336569	KBM7	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	1.2112564897008382	[754]	[4767]	8	hSpCas9	negative selection	2349396
147958334	147958357	2	+	24336569	KBM7	viability	CTGCCTTGTGATTTCCTTTAGGG	ORC4	ENSG00000115947	-0.40951115571536323	[186]	[383]	-3	hSpCas9	negative selection	2349397
147958790	147958813	2	-	24336569	KBM7	viability	GTATTACAAGTTCACTTAAATGG	ORC4	ENSG00000115947	-0.31399604217029053	[334]	[734]	-3	hSpCas9	negative selection	2349398
147971105	147971128	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGCTCTTTCACCCAGGCCGG	ORC4	ENSG00000115947	-3.4752685797456295	[670,81]	[9,2]	-9	dCas9-VP64	positive selection	2390697
148020847	148020870	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTAGGAAGGAGGAGGGAGCTGG	ORC4	ENSG00000115947	-0.1018494081677137	[47,21]	[9,2]	0	dCas9-VP64	positive selection	2408767
148020823	148020846	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAAAGTGGAGGAACGGAAGTGGG	ORC4	ENSG00000115947	0.5726520997871849	[52,134]	[37,22]	2	dCas9-VP64	positive selection	2408768
148020814	148020837	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAACGGAAGTGGGCGTGGACGG	ORC4	ENSG00000115947	-2.7137833873128034	[47,336]	[3,7]	-9	dCas9-VP64	positive selection	2408772
148020915	148020938	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GACATTGTAGCGGGAGGTACAGG	ORC4	ENSG00000115947	1.6284413800175654	[205,563]	[257,270]	6	dCas9-VP64	positive selection	2430643
148020893	148020916	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGCGGGGGCGGGGAGGAGGAGG	ORC4	ENSG00000115947	4.928777059786258	[2,10]	[26,72]	9	dCas9-VP64	positive selection	2430644
148020835	148020858	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCCTTCCTAAGGGAAAGTGGAGG	ORC4	ENSG00000115947	-1.27479052071273	[801,559]	[43,79]	-7	dCas9-VP64	positive selection	2430645
148020850	148020873	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAAGGAGGAGGGAGCTGGGGG	ORC4	ENSG00000115947	3.1390429779024425	[7,2]	[18,1]	8	dCas9-VP64	positive selection	2449915
148020922	148020945	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCCCGCTACAATGTCTTCCGGG	ORC4	ENSG00000115947	-0.2687637799695004	[234,1570]	[13,330]	-1	dCas9-VP64	positive selection	2449916
148020824	148020847	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAAAGTGGAGGAACGGAAGTGG	ORC4	ENSG00000115947	2.5011174916782015	[12,4]	[3,17]	8	dCas9-VP64	positive selection	2449917
148020962	148020985	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAATGAGCTATTTTCCCAGAAGG	ORC4	ENSG00000115947	0.8201138713746738	[517,580]	[250,173]	3	dCas9-VP64	positive selection	2473108
147971105	147971128	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGCTCTTTCACCCAGGCCGG	ORC4	ENSG00000115947	0.8980088860596516	[158,118]	[140,31]	6	dCas9-VP64	positive selection	2485952
148020847	148020870	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTAGGAAGGAGGAGGGAGCTGG	ORC4	ENSG00000115947	-0.8096733871420141	[35,42]	[7,5]	-7	dCas9-VP64	positive selection	2504022
148020823	148020846	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAAAGTGGAGGAACGGAAGTGGG	ORC4	ENSG00000115947	0.32969428973384574	[269,386]	[51,210]	2	dCas9-VP64	positive selection	2504023
148020814	148020837	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAACGGAAGTGGGCGTGGACGG	ORC4	ENSG00000115947	0.8044976087341471	[34,68]	[44,13]	5	dCas9-VP64	positive selection	2504027
148020915	148020938	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GACATTGTAGCGGGAGGTACAGG	ORC4	ENSG00000115947	0.9305549168853151	[279,277]	[159,185]	6	dCas9-VP64	positive selection	2525898
148020893	148020916	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGCGGGGGCGGGGAGGAGGAGG	ORC4	ENSG00000115947	2.8380903953642775	[3,29]	[45,32]	9	dCas9-VP64	positive selection	2525899
148020835	148020858	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCCTTCCTAAGGGAAAGTGGAGG	ORC4	ENSG00000115947	-0.05915716432455054	[406,266]	[111,99]	0	dCas9-VP64	positive selection	2525900
148020850	148020873	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAAGGAGGAGGGAGCTGGGGG	ORC4	ENSG00000115947	-0.1933217214398577	[27,78]	[16,12]	-2	dCas9-VP64	positive selection	2545170
148020922	148020945	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCCCGCTACAATGTCTTCCGGG	ORC4	ENSG00000115947	0.6319402011719197	[344,197]	[99,172]	5	dCas9-VP64	positive selection	2545171
148020824	148020847	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAAAGTGGAGGAACGGAAGTGG	ORC4	ENSG00000115947	0.5997104561624921	[52,61]	[20,34]	4	dCas9-VP64	positive selection	2545172
148020962	148020985	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAATGAGCTATTTTCCCAGAAGG	ORC4	ENSG00000115947	1.7195920346878042	[261,158]	[425,42]	8	dCas9-VP64	positive selection	2568363
147955357	147955380	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-1.0540652044350076	[3,3]	[0,1]	-9	hSpCas9	positive selection	3008934
147948156	147948179	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.39480256568980976	[4,5]	[4,1]	-5	hSpCas9	positive selection	3008935
147952484	147952507	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATCTAATATGAAGATCACTGGG	ORC4	ENSG00000115947	-0.7840252189352771	[3,3]	[1,1]	-8	hSpCas9	positive selection	3008936
147958311	147958334	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTAAATCTGGAAAATGTAGTTGG	ORC4	ENSG00000115947	-0.4397848792012862	[4,4]	[3,1]	-6	hSpCas9	positive selection	3008937
147955357	147955380	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.9437045543526933	[3,3]	[1,0]	-9	hSpCas9	positive selection	3076792
147948156	147948179	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	0.2064953283336513	[4,4]	[4,3]	3	hSpCas9	positive selection	3076793
147952484	147952507	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATCTAATATGAAGATCACTGGG	ORC4	ENSG00000115947	-1.342650194060295	[3,3]	[0,0]	-9	hSpCas9	positive selection	3076794
147958311	147958334	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTAAATCTGGAAAATGTAGTTGG	ORC4	ENSG00000115947	0.29274497588116016	[4,4]	[4,3]	5	hSpCas9	positive selection	3076795
147958348	147958371		-	24336571	A375	resistance to PLX after 7 days	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.04713909339513345	[24,31]	[27,29]	1	hSpCas9	positive selection	3133293
147955362	147955385		-	24336571	A375	resistance to PLX after 7 days	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.9987512330997104	[32,39]	[83,61]	9	hSpCas9	positive selection	3133294
147958348	147958371		-	24336571	A375	resistance to PLX after 14 days	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.8016456048166711	[18,30]	[16,23]	6	hSpCas9	positive selection	3191086
147955362	147955385		-	24336571	A375	resistance to PLX after 14 days	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	6.432038980512587	[50,33]	[1486,1994]	9	hSpCas9	positive selection	3191087
147958348	147958371		-	24336571	A375	viability after 7 days	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.2075179131114535	[25]	[24,31]	3	hSpCas9	negative selection	3248879
147955362	147955385		-	24336571	A375	viability after 7 days	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	-0.38725329554736176	[49]	[32,39]	-5	hSpCas9	negative selection	3248880
147958348	147958371		-	24336571	A375	viability after 14 days	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.06682462451180071	[25]	[18,30]	0	hSpCas9	negative selection	3306672
147955362	147955385		-	24336571	A375	viability after 14 days	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	-0.14016957190482038	[49]	[50,33]	-2	hSpCas9	negative selection	3306673
147948070	147948093	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	1.2800462879459185	[62,62]	[0,0]	5	hSpCas9	positive selection	3384139
147955362	147955385	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	-0.37203040863377457	[197,197]	[0,0]	-2	hSpCas9	positive selection	3384140
147955356	147955379	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	1.4759664979211755	[54,54]	[0,0]	6	hSpCas9	positive selection	3384141
147955356	147955379	2	+	26780180	HT29	viability (Avana library 4 designs)	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	2.90137758591969	[]	[]	8	hSpCas9	negative selection	3446942
147948155	147948178	2	+	26780180	HT29	viability (Avana library 4 designs)	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	2.71879436131	[]	[]	8	hSpCas9	negative selection	3446943
147952483	147952506	2	+	26780180	HT29	viability (Avana library 4 designs)	CATCTAATATGAAGATCACTGGG	ORC4	ENSG00000115947	3.63370618436111	[]	[]	9	hSpCas9	negative selection	3446944
147958311	147958334	2	-	26780180	HT29	viability (Avana library 4 designs)	TTAAATCTGGAAAATGTAGTTGG	ORC4	ENSG00000115947	0.668179050801014	[]	[]	2	hSpCas9	negative selection	3446945
147955356	147955379	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-7.06941647112875	[]	[]	-6	hSpCas9	negative selection	3540504
147948155	147948178	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-22.858876827524	[]	[]	-9	hSpCas9	negative selection	3540505
147958311	147958334	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTAAATCTGGAAAATGTAGTTGG	ORC4	ENSG00000115947	-11.0931364096921	[]	[]	-8	hSpCas9	negative selection	3540506
147952483	147952506	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATCTAATATGAAGATCACTGGG	ORC4	ENSG00000115947	-23.4390364646117	[]	[]	-9	hSpCas9	negative selection	3540507
147958333	147958356	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGCCTTGTGATTTCCTTTAGG	ORC4	ENSG00000115947	2.53648489347584	[]	[]	4	hSpCas9	negative selection	3540508
147958337	147958360	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-8.45544164004123	[]	[]	-7	hSpCas9	negative selection	3540509
147955356	147955379	2	+	26780180	A375	viability (Avana lentiGuide)	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	7.32301642214702	[]	[]	6	hSpCas9	negative selection	3649163
147948155	147948178	2	+	26780180	A375	viability (Avana lentiGuide)	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	31.208456336157	[]	[]	9	hSpCas9	negative selection	3649164
147958311	147958334	2	-	26780180	A375	viability (Avana lentiGuide)	TTAAATCTGGAAAATGTAGTTGG	ORC4	ENSG00000115947	-6.71889268779614	[]	[]	-9	hSpCas9	negative selection	3649165
147952483	147952506	2	+	26780180	A375	viability (Avana lentiGuide)	CATCTAATATGAAGATCACTGGG	ORC4	ENSG00000115947	3.10452335336723	[]	[]	3	hSpCas9	negative selection	3649166
147958333	147958356	2	+	26780180	A375	viability (Avana lentiGuide)	ACTGCCTTGTGATTTCCTTTAGG	ORC4	ENSG00000115947	-5.21066798467865	[]	[]	-8	hSpCas9	negative selection	3649167
147958337	147958360	2	-	26780180	A375	viability (Avana lentiGuide)	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	26.7199175101591	[]	[]	9	hSpCas9	negative selection	3649168
147955356	147955379	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.31972390018663277	[6]	[5,3]	-5	hSpCas9	positive selection	3757822
147948155	147948178	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.8347770572797977	[8]	[4,4]	-8	hSpCas9	positive selection	3757823
147958311	147958334	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAAATCTGGAAAATGTAGTTGG	ORC4	ENSG00000115947	-0.5977582091074174	[9]	[5,4]	-7	hSpCas9	positive selection	3757824
147952483	147952506	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCTAATATGAAGATCACTGGG	ORC4	ENSG00000115947	-1.0603969166475857	[8]	[3,3]	-9	hSpCas9	positive selection	3757825
147958333	147958356	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGCCTTGTGATTTCCTTTAGG	ORC4	ENSG00000115947	0.147174505919278	[5]	[6,5]	4	hSpCas9	positive selection	3757826
147958337	147958360	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-1.068615499756737	[4]	[2,0]	-9	hSpCas9	positive selection	3757827
147955356	147955379	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.3976422806563737	[4]	[1,3]	-5	hSpCas9	positive selection	3866429
147948155	147948178	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-1.0612610249453711	[7]	[5,0]	-8	hSpCas9	positive selection	3866430
147958311	147958334	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAAATCTGGAAAATGTAGTTGG	ORC4	ENSG00000115947	0.25714584955768427	[6]	[6,6]	7	hSpCas9	positive selection	3866431
147952483	147952506	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCTAATATGAAGATCACTGGG	ORC4	ENSG00000115947	-0.16256991523487774	[4]	[3,2]	-2	hSpCas9	positive selection	3866432
147958333	147958356	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGCCTTGTGATTTCCTTTAGG	ORC4	ENSG00000115947	0.37053659539999584	[6]	[7,6]	9	hSpCas9	positive selection	3866433
147958337	147958360	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-1.3076428304272423	[5]	[0,1]	-9	hSpCas9	positive selection	3866434
147955356	147955379	2	+	26780180	A375	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	1.21523915852405	[]	[]	6	hSpCas9	negative selection	3977343
147958324	147958347	2	-	26780180	A375	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.761229010752335	[]	[]	3	hSpCas9	negative selection	3977344
147948155	147948178	2	+	26780180	A375	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	1.77971961793567	[]	[]	9	hSpCas9	negative selection	3977345
147958348	147958371	2	-	26780180	A375	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	1.08272778250755	[]	[]	5	hSpCas9	negative selection	3977346
147955362	147955385	2	-	26780180	A375	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.417148270070441	[]	[]	1	hSpCas9	negative selection	3977347
147948070	147948093	2	+	26780180	A375	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	1.17001834735458	[]	[]	6	hSpCas9	negative selection	3977348
147955356	147955379	2	+	26780180	HT29	viability (GeCKOv2 library)	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	1.33732090616878	[]	[]	6	hSpCas9	negative selection	4085309
147958324	147958347	2	-	26780180	HT29	viability (GeCKOv2 library)	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	1.30031020338757	[]	[]	6	hSpCas9	negative selection	4085310
147948155	147948178	2	+	26780180	HT29	viability (GeCKOv2 library)	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	1.96969793213185	[]	[]	9	hSpCas9	negative selection	4085311
147958348	147958371	2	-	26780180	HT29	viability (GeCKOv2 library)	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.488609465568799	[]	[]	1	hSpCas9	negative selection	4085312
147955362	147955385	2	-	26780180	HT29	viability (GeCKOv2 library)	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.365868549724698	[]	[]	1	hSpCas9	negative selection	4085313
147948070	147948093	2	+	26780180	HT29	viability (GeCKOv2 library)	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	1.12870394864068	[]	[]	5	hSpCas9	negative selection	4085314
147958348	147958371	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.09655928653580109	[4]	[2,4]	2	hSpCas9	positive selection	4158105
147955362	147955385	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.8433140895910746	[5]	[3,10]	9	hSpCas9	positive selection	4158106
147958348	147958371	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	-0.24200852952626728	[5]	[4,0,2,0]	-4	hSpCas9	positive selection	4222127
147955362	147955385	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.9857689014129525	[5]	[4,4,3,4]	7	hSpCas9	positive selection	4222128
147958348	147958371	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.5239873387294699	[2]	[2,2]	9	hSpCas9	positive selection	4288259
147958324	147958347	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.13050076705376717	[3]	[3,2]	2	hSpCas9	positive selection	4288260
147948155	147948178	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.6116256831360307	[2]	[1,0]	-8	hSpCas9	positive selection	4288261
147948070	147948093	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	0.024204021352364102	[1]	[2,0]	0	hSpCas9	positive selection	4352514
147955362	147955385	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.22415860549689995	[2]	[2,1]	4	hSpCas9	positive selection	4352515
147955356	147955379	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.1618120373791998	[2]	[1,1]	-3	hSpCas9	positive selection	4352516
147939194	147939216	2	+	27760321	OCIAML3	viability	GATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.3729912468006811	[98,102]	[84,125]	4	hSpCas9	negative selection	4424735
147943439	147943461	2	+	27760321	OCIAML3	viability	TAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-1.3640953787184071	[657,594]	[141,252]	-8	hSpCas9	negative selection	4424736
147952372	147952394	2	-	27760321	OCIAML3	viability	ATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	1.4675366322813241	[25,20]	[40,62]	9	hSpCas9	negative selection	4424737
147952483	147952505	2	+	27760321	OCIAML3	viability	CATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	0.6404923308120147	[67,48]	[67,73]	7	hSpCas9	negative selection	4424738
147958324	147958346	2	-	27760321	OCIAML3	viability	ATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	-1.0762787425898692	[127,113]	[36,54]	-7	hSpCas9	negative selection	4424739
147939194	147939216	2	+	27760321	OCIAML2	viability	GATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-0.590524315130089	[98,102]	[60,45]	-6	hSpCas9	negative selection	4508198
147943439	147943461	2	+	27760321	OCIAML2	viability	TAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.8358070142151764	[657,594]	[262,310]	-7	hSpCas9	negative selection	4508199
147952372	147952394	2	-	27760321	OCIAML2	viability	ATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	-0.9189239139258838	[25,20]	[9,9]	-7	hSpCas9	negative selection	4508200
147952483	147952505	2	+	27760321	OCIAML2	viability	CATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	-2.7340614802599497	[67,48]	[0,14]	-9	hSpCas9	negative selection	4508201
147958324	147958346	2	-	27760321	OCIAML2	viability	ATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.1584434114354656	[127,113]	[137,70]	2	hSpCas9	negative selection	4508202
147939194	147939216	2	+	27760321	MV411	viability	GATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-1.039591265362564	[98,102]	[10,64]	-6	hSpCas9	negative selection	4591661
147943439	147943461	2	+	27760321	MV411	viability	TAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-2.3658071311742517	[657,594]	[8,186]	-8	hSpCas9	negative selection	4591662
147952372	147952394	2	-	27760321	MV411	viability	ATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	-3.947028074633515	[25,20]	[0,0]	-9	hSpCas9	negative selection	4591663
147952483	147952505	2	+	27760321	MV411	viability	CATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	-2.293688209840643	[67,48]	[0,17]	-8	hSpCas9	negative selection	4591664
147958324	147958346	2	-	27760321	MV411	viability	ATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.6475272622456449	[127,113]	[0,310]	5	hSpCas9	negative selection	4591665
147939194	147939216	2	+	27760321	HL60	viability	GATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.31297326866307595	[98,102]	[135,67]	4	hSpCas9	negative selection	4675124
147943439	147943461	2	+	27760321	HL60	viability	TAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.7903038087585734	[657,594]	[350,236]	-7	hSpCas9	negative selection	4675125
147952372	147952394	2	-	27760321	HL60	viability	ATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	-2.0524772359963785	[25,20]	[7,0]	-9	hSpCas9	negative selection	4675126
147952483	147952505	2	+	27760321	HL60	viability	CATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	-0.9692507979770242	[67,48]	[12,35]	-7	hSpCas9	negative selection	4675127
147958324	147958346	2	-	27760321	HL60	viability	ATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.3712823188776204	[127,113]	[99,156]	4	hSpCas9	negative selection	4675128
147939194	147939216	2	+	27760321	HT1080	viability	GATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-5.1964225825650825	[102,80]	[0,0]	-8	hSpCas9	negative selection	4758587
147943439	147943461	2	+	27760321	HT1080	viability	TAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-7.720597527805281	[594,463]	[0,0]	-9	hSpCas9	negative selection	4758588
147952372	147952394	2	-	27760321	HT1080	viability	ATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	-2.9233782605522816	[20,16]	[0,0]	-7	hSpCas9	negative selection	4758589
147952483	147952505	2	+	27760321	HT1080	viability	CATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	-4.114558017842154	[48,37]	[0,0]	-8	hSpCas9	negative selection	4758590
147958324	147958346	2	-	27760321	HT1080	viability	ATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	-5.337546114314766	[113,88]	[0,0]	-8	hSpCas9	negative selection	4758591
147939194	147939216	2	+	27760321	HT29	viability after 7 days	GATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.127149029890393	[102,80]	[52,172,149]	2	hSpCas9	negative selection	4842050
147943439	147943461	2	+	27760321	HT29	viability after 7 days	TAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-1.2861178956637358	[594,463]	[341,256,247]	-9	hSpCas9	negative selection	4842051
147952372	147952394	2	-	27760321	HT29	viability after 7 days	ATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	0.32202380945321707	[20,16]	[36,34,20]	5	hSpCas9	negative selection	4842052
147952483	147952505	2	+	27760321	HT29	viability after 7 days	CATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	-1.2599545385705229	[48,37]	[44,1,25]	-9	hSpCas9	negative selection	4842053
147958324	147958346	2	-	27760321	HT29	viability after 7 days	ATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.10198265714917798	[113,88]	[89,155,165]	1	hSpCas9	negative selection	4842054
147939194	147939216	2	+	27760321	HT29	viability after 25 days	GATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-1.0533180971518712	[102,80]	[39,58,53]	-6	hSpCas9	negative selection	4925513
147943439	147943461	2	+	27760321	HT29	viability after 25 days	TAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-2.591420028746309	[594,463]	[111,81,106]	-8	hSpCas9	negative selection	4925514
147952372	147952394	2	-	27760321	HT29	viability after 25 days	ATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	-4.443060525398805	[20,16]	[0,0,0]	-9	hSpCas9	negative selection	4925515
147952483	147952505	2	+	27760321	HT29	viability after 25 days	CATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	-2.5867997058755146	[48,37]	[0,0,24]	-8	hSpCas9	negative selection	4925516
147958324	147958346	2	-	27760321	HT29	viability after 25 days	ATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	-1.6435935609141645	[113,88]	[31,4,78]	-7	hSpCas9	negative selection	4925517
147939194	147939216	2	+	27760321	HT29	viability after 22 days	GATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-1.7666430391661547	[102,80]	[0,23,69]	-8	hSpCas9	negative selection	5008976
147943439	147943461	2	+	27760321	HT29	viability after 22 days	TAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-2.1009447094975178	[594,463]	[276,47,98]	-8	hSpCas9	negative selection	5008977
147952372	147952394	2	-	27760321	HT29	viability after 22 days	ATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	-4.460379157258065	[20,16]	[0,0,0]	-9	hSpCas9	negative selection	5008978
147952483	147952505	2	+	27760321	HT29	viability after 22 days	CATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	-4.250328024459566	[48,37]	[0,0,5]	-9	hSpCas9	negative selection	5008979
147958324	147958346	2	-	27760321	HT29	viability after 22 days	ATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	-0.3135597453022423	[113,88]	[103,83,94]	-3	hSpCas9	negative selection	5008980
147939194	147939216	2	+	27760321	HT29	viability after 19 days	GATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-2.033061247238349	[102,80]	[19,42,13]	-8	hSpCas9	negative selection	5092439
147943439	147943461	2	+	27760321	HT29	viability after 19 days	TAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-2.7328191718233077	[594,463]	[139,64,73]	-8	hSpCas9	negative selection	5092440
147952372	147952394	2	-	27760321	HT29	viability after 19 days	ATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	-4.444539104834852	[20,16]	[0,0,0]	-9	hSpCas9	negative selection	5092441
147952483	147952505	2	+	27760321	HT29	viability after 19 days	CATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	-4.591606971556403	[48,37]	[0,0,3]	-9	hSpCas9	negative selection	5092442
147958324	147958346	2	-	27760321	HT29	viability after 19 days	ATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	-0.04047325594759088	[113,88]	[151,6,180]	0	hSpCas9	negative selection	5092443
147939194	147939216	2	+	27760321	HT29	viability after 16 days	GATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-3.4685275911640936	[102,80]	[0,13,11]	-9	hSpCas9	negative selection	5175902
147943439	147943461	2	+	27760321	HT29	viability after 16 days	TAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-1.9582417857466843	[594,463]	[164,132,160]	-8	hSpCas9	negative selection	5175903
147952372	147952394	2	-	27760321	HT29	viability after 16 days	ATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	-4.41307465241393	[20,16]	[0,0,0]	-9	hSpCas9	negative selection	5175904
147952483	147952505	2	+	27760321	HT29	viability after 16 days	CATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	-5.6042544097038025	[48,37]	[0,0,0]	-9	hSpCas9	negative selection	5175905
147958324	147958346	2	-	27760321	HT29	viability after 16 days	ATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	-0.717318507181862	[113,88]	[12,141,44]	-6	hSpCas9	negative selection	5175906
147939194	147939216	2	+	27760321	HT29	viability after 13 days	GATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-1.3960334243538932	[102,80]	[64,38,18]	-8	hSpCas9	negative selection	5259365
147943439	147943461	2	+	27760321	HT29	viability after 13 days	TAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-1.150535806438545	[594,463]	[331,205,290]	-7	hSpCas9	negative selection	5259366
147952372	147952394	2	-	27760321	HT29	viability after 13 days	ATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	-3.705542861338678	[20,16]	[0,0,2]	-9	hSpCas9	negative selection	5259367
147952483	147952505	2	+	27760321	HT29	viability after 13 days	CATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	-2.4262998195110246	[48,37]	[4,10,11]	-9	hSpCas9	negative selection	5259368
147958324	147958346	2	-	27760321	HT29	viability after 13 days	ATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	-0.11663482513884582	[113,88]	[94,107,121]	-1	hSpCas9	negative selection	5259369
147939194	147939216	2	+	27760321	HT29	viability after 10 days	GATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-0.9188895589071471	[102,80]	[35,44,99]	-7	hSpCas9	negative selection	5342828
147943439	147943461	2	+	27760321	HT29	viability after 10 days	TAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.6844628952350542	[594,463]	[201,705,335]	-7	hSpCas9	negative selection	5342829
147952372	147952394	2	-	27760321	HT29	viability after 10 days	ATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	-1.8804524988327902	[20,16]	[1,0,15]	-9	hSpCas9	negative selection	5342830
147952483	147952505	2	+	27760321	HT29	viability after 10 days	CATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	-1.8265578051959652	[48,37]	[12,17,14]	-9	hSpCas9	negative selection	5342831
147958324	147958346	2	-	27760321	HT29	viability after 10 days	ATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.17355848090457981	[113,88]	[60,103,259]	2	hSpCas9	negative selection	5342832
147939194	147939216	2	+	27760321	MOLM13	viability	GATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-0.32121636937712195	[98,102]	[0,83]	-2	hSpCas9	negative selection	5426291
147943439	147943461	2	+	27760321	MOLM13	viability	TAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-2.26687323513777	[657,594]	[0,134]	-8	hSpCas9	negative selection	5426292
147952372	147952394	2	-	27760321	MOLM13	viability	ATTGGTCTTACATGTAGATTGG	ORC4	ENSG00000115947	-3.7209712618059196	[25,20]	[0,0]	-9	hSpCas9	negative selection	5426293
147952483	147952505	2	+	27760321	MOLM13	viability	CATCTAATATGAAGATCACTGG	ORC4	ENSG00000115947	-5.0300622465653255	[67,48]	[0,0]	-9	hSpCas9	negative selection	5426294
147958324	147958346	2	-	27760321	MOLM13	viability	ATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	-2.3954842357450925	[127,113]	[26,0]	-8	hSpCas9	negative selection	5426295
148020434	148020457	2	+	27661255	K562	viability	GGGCGGGAGTGGCCACAAGACGG	ORC4	ENSG00000115947	-0.027053342616609077	[791,681]	[628,536]	-1	dCas9-KRAB	negative selection	5499504
148020720	148020743	2	+	27661255	K562	viability	GGACCGTACACAACCACTCCCGG	ORC4	ENSG00000115947	-0.07466652803583873	[1513,1377]	[1197,1013]	-3	dCas9-KRAB	negative selection	5499505
148020269	148020292	2	-	27661255	K562	viability	GGACGGAGGACTTCTATCTAGGG	ORC4	ENSG00000115947	-0.21899947335000353	[627,801]	[568,419]	-6	dCas9-KRAB	negative selection	5499506
148020329	148020352	2	-	27661255	K562	viability	GGTCCGAGTGTAAGAGAGAAGGG	ORC4	ENSG00000115947	-0.0713788445321285	[1039,1342]	[966,845]	-3	dCas9-KRAB	negative selection	5499507
148020350	148020373	2	-	27661255	K562	viability	GTAGTAGGTGAGGAGCGTGACGG	ORC4	ENSG00000115947	0.12827351722267644	[915,1068]	[1017,732]	4	dCas9-KRAB	negative selection	5499508
148020674	148020697	2	-	27661255	K562	viability	GAGGACGCGGCCAGGCGATTCGG	ORC4	ENSG00000115947	-0.35414742051252485	[536,635]	[359,369]	-7	dCas9-KRAB	negative selection	5499509
148020687	148020710	2	-	27661255	K562	viability	GTGAAGTCTAGCAGAGGACGCGG	ORC4	ENSG00000115947	-0.059717898762881125	[910,788]	[691,619]	-2	dCas9-KRAB	negative selection	5499510
147958348	147958371	2	-	27260156	BXPC3	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.2469223646872093	[216]	[229,282,296,268]	5	hSpCas9	negative selection	5560719
147958324	147958347	2	-	27260156	BXPC3	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.2888964591054415	[567]	[730,650,778,742]	6	hSpCas9	negative selection	5560720
147948155	147948178	2	+	27260156	BXPC3	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.6633269127983203	[252]	[144,191,128,205]	-8	hSpCas9	negative selection	5560721
147948070	147948093	2	+	27260156	BXPC3	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.002515665915628018	[162]	[143,163,156,223]	0	hSpCas9	negative selection	5624974
147955362	147955385	2	-	27260156	BXPC3	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.6634824581996681	[244]	[425,334,422,442]	9	hSpCas9	negative selection	5624975
147955356	147955379	2	+	27260156	BXPC3	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	0.06470230933442389	[222]	[238,183,196,372]	1	hSpCas9	negative selection	5624976
147958348	147958371	2	-	27260156	A673	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	-0.4264338016309608	[216]	[192,171,163,249]	-8	hSpCas9	negative selection	5681970
147958324	147958347	2	-	27260156	A673	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.03180600529483507	[567]	[692,625,861,600]	0	hSpCas9	negative selection	5681971
147948155	147948178	2	+	27260156	A673	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.8314977113429018	[252]	[203,104,130,252]	-9	hSpCas9	negative selection	5681972
147948070	147948093	2	+	27260156	A673	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.05707902847455526	[162]	[111,188,234,207]	-1	hSpCas9	negative selection	5746225
147955362	147955385	2	-	27260156	A673	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.807289925975574	[244]	[566,575,471,443]	9	hSpCas9	negative selection	5746226
147955356	147955379	2	+	27260156	A673	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.21067599104492563	[222]	[273,218,213,222]	-5	hSpCas9	negative selection	5746227
147958348	147958371	2	-	27260156	A375	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.058168956087104595	[216]	[308,323,256,182]	0	hSpCas9	negative selection	5803221
147958324	147958347	2	-	27260156	A375	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.7185408607197175	[567]	[974,1436,752,1227]	9	hSpCas9	negative selection	5803222
147948155	147948178	2	+	27260156	A375	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.8702147371160447	[252]	[174,175,189,112]	-8	hSpCas9	negative selection	5803223
147948070	147948093	2	+	27260156	A375	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.5794004191178463	[162]	[99,224,129,73]	-7	hSpCas9	negative selection	5867476
147955362	147955385	2	-	27260156	A375	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	1.1479998285452535	[244]	[802,715,617,433]	9	hSpCas9	negative selection	5867477
147955356	147955379	2	+	27260156	A375	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-1.0473113148592255	[222]	[89,76,179,146]	-8	hSpCas9	negative selection	5867478
147958348	147958371	2	-	27260156	COLO741	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.14989862857334524	[216]	[370,256,299]	3	hSpCas9	negative selection	5924472
147958324	147958347	2	-	27260156	COLO741	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	-0.06285974547999645	[567]	[743,565,770]	-1	hSpCas9	negative selection	5924473
147948155	147948178	2	+	27260156	COLO741	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.7365461585878237	[252]	[242,250,98]	-9	hSpCas9	negative selection	5924474
147948070	147948093	2	+	27260156	COLO741	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.12836752962307973	[162]	[276,147,155]	-3	hSpCas9	negative selection	5988727
147955362	147955385	2	-	27260156	COLO741	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.5394461828901813	[244]	[574,401,400]	9	hSpCas9	negative selection	5988728
147955356	147955379	2	+	27260156	COLO741	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.3950031804002536	[222]	[183,261,201]	-7	hSpCas9	negative selection	5988729
147958348	147958371	2	-	27260156	CAL120	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.8647411563475582	[216]	[885,250,398]	9	hSpCas9	negative selection	6045723
147958324	147958347	2	-	27260156	CAL120	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.13902304878886412	[567]	[685,759,872]	2	hSpCas9	negative selection	6045724
147948155	147948178	2	+	27260156	CAL120	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-1.075834767113955	[252]	[157,180,110]	-8	hSpCas9	negative selection	6045725
147948070	147948093	2	+	27260156	CAL120	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	0.048458122004799264	[162]	[227,252,151]	0	hSpCas9	negative selection	6109978
147955362	147955385	2	-	27260156	CAL120	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.6753478697706057	[244]	[827,377,308]	8	hSpCas9	negative selection	6109979
147955356	147955379	2	+	27260156	CAL120	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.4258706783863566	[222]	[108,292,202]	-6	hSpCas9	negative selection	6109980
147958348	147958371	2	-	27260156	CADOES1	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.36072219866460975	[216]	[188,243,388,212]	6	hSpCas9	negative selection	6166974
147958324	147958347	2	-	27260156	CADOES1	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.15115331384339337	[567]	[628,603,537,574]	2	hSpCas9	negative selection	6166975
147948155	147948178	2	+	27260156	CADOES1	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.2531124680748815	[252]	[148,242,199,197]	-4	hSpCas9	negative selection	6166976
147948070	147948093	2	+	27260156	CADOES1	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	0.5893293722315807	[162]	[224,119,239,330]	8	hSpCas9	negative selection	6231229
147955362	147955385	2	-	27260156	CADOES1	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.9383357360476732	[244]	[387,364,469,526]	9	hSpCas9	negative selection	6231230
147955356	147955379	2	+	27260156	CADOES1	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.46716318593331985	[222]	[140,150,161,145]	-7	hSpCas9	negative selection	6231231
147958348	147958371	2	-	27260156	EWS502	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.3847833128888717	[216]	[223,293,262,436]	6	hSpCas9	negative selection	6288225
147958324	147958347	2	-	27260156	EWS502	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.15019958334889116	[567]	[493,540,926,740]	2	hSpCas9	negative selection	6288226
147948155	147948178	2	+	27260156	EWS502	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.7665200592728401	[252]	[91,228,179,131]	-8	hSpCas9	negative selection	6288227
147948070	147948093	2	+	27260156	EWS502	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	0.34599078066288524	[162]	[153,242,276,209]	6	hSpCas9	negative selection	6352480
147955362	147955385	2	-	27260156	EWS502	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.8539008977983291	[244]	[395,560,454,466]	9	hSpCas9	negative selection	6352481
147955356	147955379	2	+	27260156	EWS502	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.8789441685598016	[222]	[115,110,158,129]	-8	hSpCas9	negative selection	6352482
147958348	147958371	2	-	27260156	EW8	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.15542862862177564	[216]	[155,148,177,297]	3	hSpCas9	negative selection	6409476
147958324	147958347	2	-	27260156	EW8	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.2923287645039455	[567]	[718,540,422,610]	5	hSpCas9	negative selection	6409477
147948155	147948178	2	+	27260156	EW8	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.32390775940857397	[252]	[203,175,141,140]	-6	hSpCas9	negative selection	6409478
147948070	147948093	2	+	27260156	EW8	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	0.39494558192775386	[162]	[201,76,135,287]	7	hSpCas9	negative selection	6473731
147955362	147955385	2	-	27260156	EW8	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	1.0018196491014282	[244]	[486,360,409,338]	9	hSpCas9	negative selection	6473732
147955356	147955379	2	+	27260156	EW8	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.6313043982458804	[222]	[110,117,36,212]	-8	hSpCas9	negative selection	6473733
147958348	147958371	2	-	27260156	CORL105	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	-0.10217217408354884	[216]	[218,267,308,160]	-2	hSpCas9	negative selection	6530727
147958324	147958347	2	-	27260156	CORL105	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.10659330515296889	[567]	[703,728,816,628]	2	hSpCas9	negative selection	6530728
147948155	147948178	2	+	27260156	CORL105	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.023750142131027996	[252]	[460,145,365,212]	0	hSpCas9	negative selection	6530729
147948070	147948093	2	+	27260156	CORL105	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.0465201600690468	[162]	[152,195,155,227]	-1	hSpCas9	negative selection	6594982
147955362	147955385	2	-	27260156	CORL105	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.7381856871113709	[244]	[422,423,657,435]	9	hSpCas9	negative selection	6594983
147955356	147955379	2	+	27260156	CORL105	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.49604898301306233	[222]	[199,186,166,183]	-7	hSpCas9	negative selection	6594984
147958348	147958371	2	-	27260156	HS294T	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.46064639580551103	[216]	[130,106,92,131]	6	hSpCas9	negative selection	6651978
147958324	147958347	2	-	27260156	HS294T	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.48180096225723545	[567]	[325,332,161,420]	6	hSpCas9	negative selection	6651979
147948155	147948178	2	+	27260156	HS294T	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.03669411204113371	[252]	[67,63,111,149]	0	hSpCas9	negative selection	6651980
147948070	147948093	2	+	27260156	HS294T	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	0.03934032442576374	[162]	[30,69,85,76]	0	hSpCas9	negative selection	6716233
147955362	147955385	2	-	27260156	HS294T	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.34287681237302725	[244]	[85,191,87,113]	4	hSpCas9	negative selection	6716234
147955356	147955379	2	+	27260156	HS294T	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-1.263657668904382	[222]	[18,21,61,43]	-9	hSpCas9	negative selection	6716235
147958348	147958371	2	-	27260156	HCC44	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.03686453703104586	[216]	[285,118,425,226]	0	hSpCas9	negative selection	6773229
147958324	147958347	2	-	27260156	HCC44	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.12694384149959087	[567]	[675,582,847,731]	2	hSpCas9	negative selection	6773230
147948155	147948178	2	+	27260156	HCC44	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-1.2878842934803743	[252]	[48,212,134,55]	-9	hSpCas9	negative selection	6773231
147948070	147948093	2	+	27260156	HCC44	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.43632868126962343	[162]	[219,59,130,149]	-6	hSpCas9	negative selection	6837484
147955362	147955385	2	-	27260156	HCC44	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.3909024342367524	[244]	[468,251,483,293]	6	hSpCas9	negative selection	6837485
147955356	147955379	2	+	27260156	HCC44	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.8041900396769603	[222]	[100,14,364,147]	-8	hSpCas9	negative selection	6837486
147958348	147958371	2	-	27260156	G402	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.5135892713825185	[216]	[168,695,470,172]	6	hSpCas9	negative selection	6894480
147958324	147958347	2	-	27260156	G402	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.3683531871023721	[567]	[1077,817,631,1060]	4	hSpCas9	negative selection	6894481
147948155	147948178	2	+	27260156	G402	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.728627780641155	[252]	[146,68,435,84]	-7	hSpCas9	negative selection	6894482
147948070	147948093	2	+	27260156	G402	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.4880340718329288	[162]	[76,158,109,208]	-6	hSpCas9	negative selection	6958735
147955362	147955385	2	-	27260156	G402	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	1.2718829587018687	[244]	[622,951,695,617]	9	hSpCas9	negative selection	6958736
147955356	147955379	2	+	27260156	G402	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.7918348184332031	[222]	[265,174,113,92]	-7	hSpCas9	negative selection	6958737
147958348	147958371	2	-	27260156	L33	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.11675305261674307	[216]	[195,82,160,286]	2	hSpCas9	negative selection	7015731
147958324	147958347	2	-	27260156	L33	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.21529068712623267	[567]	[689,264,319,788]	5	hSpCas9	negative selection	7015732
147948155	147948178	2	+	27260156	L33	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.06408687519656875	[252]	[211,115,135,256]	-1	hSpCas9	negative selection	7015733
147948070	147948093	2	+	27260156	L33	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	0.47244523639585445	[162]	[231,50,187,248]	8	hSpCas9	negative selection	7079986
147955362	147955385	2	-	27260156	L33	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.4035795977402291	[244]	[365,162,159,276]	8	hSpCas9	negative selection	7079987
147955356	147955379	2	+	27260156	L33	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.09922864303851142	[222]	[186,77,160,199]	-2	hSpCas9	negative selection	7079988
147958348	147958371	2	-	27260156	K562	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.4076372902456519	[216]	[328,437,142,139]	5	hSpCas9	negative selection	7136982
147958324	147958347	2	-	27260156	K562	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.2434951743027498	[567]	[373,608,722,653]	3	hSpCas9	negative selection	7136983
147948155	147948178	2	+	27260156	K562	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.7147445657808087	[252]	[215,130,51,151]	-7	hSpCas9	negative selection	7136984
147948070	147948093	2	+	27260156	K562	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.5524064567071059	[162]	[240,59,81,28]	-6	hSpCas9	negative selection	7201237
147955362	147955385	2	-	27260156	K562	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	1.095418085303594	[244]	[542,477,354,484]	9	hSpCas9	negative selection	7201238
147955356	147955379	2	+	27260156	K562	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.029382395598843036	[222]	[136,112,256,251]	0	hSpCas9	negative selection	7201239
147958348	147958371	2	-	27260156	HT29	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.2950733626357851	[216]	[316,313,354,306]	6	hSpCas9	negative selection	7258233
147958324	147958347	2	-	27260156	HT29	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.2598689766611125	[567]	[748,925,922,718]	5	hSpCas9	negative selection	7258234
147948155	147948178	2	+	27260156	HT29	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.7099696152403849	[252]	[159,185,237,166]	-8	hSpCas9	negative selection	7258235
147948070	147948093	2	+	27260156	HT29	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.20117429116581897	[162]	[166,165,188,165]	-4	hSpCas9	negative selection	7322488
147955362	147955385	2	-	27260156	HT29	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.8776148030685537	[244]	[725,412,356,674]	9	hSpCas9	negative selection	7322489
147955356	147955379	2	+	27260156	HT29	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.989017467652928	[222]	[137,121,172,113]	-8	hSpCas9	negative selection	7322490
147958348	147958371	2	-	27260156	MHHES1	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.25112180786318383	[216]	[330,228,408,206]	4	hSpCas9	negative selection	7379484
147958324	147958347	2	-	27260156	MHHES1	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.06244560519434439	[567]	[544,733,779,604]	1	hSpCas9	negative selection	7379485
147948155	147948178	2	+	27260156	MHHES1	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	0.10076910147120577	[252]	[258,405,302,261]	1	hSpCas9	negative selection	7379486
147948070	147948093	2	+	27260156	MHHES1	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.298691869993599	[162]	[321,114,73,108]	-5	hSpCas9	negative selection	7443739
147955362	147955385	2	-	27260156	MHHES1	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.9297968677294086	[244]	[759,503,516,371]	9	hSpCas9	negative selection	7443740
147955356	147955379	2	+	27260156	MHHES1	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.9129706342493835	[222]	[117,36,243,122]	-9	hSpCas9	negative selection	7443741
147958348	147958371	2	-	27260156	MEWO	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	-0.045590482567563484	[216]	[281,111,212]	-1	hSpCas9	negative selection	7500735
147958324	147958347	2	-	27260156	MEWO	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	-0.29929209761711584	[567]	[587,366,370]	-6	hSpCas9	negative selection	7500736
147948155	147948178	2	+	27260156	MEWO	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.6645968203562551	[252]	[144,169,131]	-8	hSpCas9	negative selection	7500737
147948070	147948093	2	+	27260156	MEWO	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	0.17895388097447662	[162]	[229,168,129]	4	hSpCas9	negative selection	7564990
147955362	147955385	2	-	27260156	MEWO	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.7947953921515218	[244]	[469,369,366]	9	hSpCas9	negative selection	7564991
147955356	147955379	2	+	27260156	MEWO	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.08647299431540545	[222]	[216,279,95]	-2	hSpCas9	negative selection	7564992
147958348	147958371	2	-	27260156	LNCAPCLONEFGC	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.5705163918096882	[216]	[333,300,331,204]	8	hSpCas9	negative selection	7621986
147958324	147958347	2	-	27260156	LNCAPCLONEFGC	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.3913830987407628	[567]	[591,616,711,788]	6	hSpCas9	negative selection	7621987
147948155	147948178	2	+	27260156	LNCAPCLONEFGC	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-1.320853771882473	[252]	[94,48,93,131]	-9	hSpCas9	negative selection	7621988
147948070	147948093	2	+	27260156	LNCAPCLONEFGC	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.02294953661185528	[162]	[137,106,253,100]	0	hSpCas9	negative selection	7686241
147955362	147955385	2	-	27260156	LNCAPCLONEFGC	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.9247646908104382	[244]	[507,349,454,379]	9	hSpCas9	negative selection	7686242
147955356	147955379	2	+	27260156	LNCAPCLONEFGC	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.5723316425248091	[222]	[124,128,81,199]	-7	hSpCas9	negative selection	7686243
147958348	147958371	2	-	27260156	PANC0327	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.4935582066676776	[216]	[161,430,283,178]	7	hSpCas9	negative selection	7743237
147958324	147958347	2	-	27260156	PANC0327	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.12495025436402318	[567]	[609,613,375,596]	1	hSpCas9	negative selection	7743238
147948155	147948178	2	+	27260156	PANC0327	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.28427816449780785	[252]	[94,161,340,135]	-4	hSpCas9	negative selection	7743239
147948070	147948093	2	+	27260156	PANC0327	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.12841334358924694	[162]	[132,114,90,192]	-2	hSpCas9	negative selection	7807492
147955362	147955385	2	-	27260156	PANC0327	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.37809660806061507	[244]	[240,319,253,307]	5	hSpCas9	negative selection	7807493
147955356	147955379	2	+	27260156	PANC0327	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.97862932869123	[222]	[107,136,98,53]	-8	hSpCas9	negative selection	7807494
147958348	147958371	2	-	27260156	NCIH2009	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.18405991181732362	[216]	[412,304,328]	2	hSpCas9	negative selection	7864488
147958324	147958347	2	-	27260156	NCIH2009	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.002358774748383752	[567]	[877,779,741]	0	hSpCas9	negative selection	7864489
147948155	147948178	2	+	27260156	NCIH2009	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	0.0801708236275489	[252]	[492,317,333]	1	hSpCas9	negative selection	7864490
147948070	147948093	2	+	27260156	NCIH2009	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.3000820475417234	[162]	[160,176,211]	-4	hSpCas9	negative selection	7928743
147955362	147955385	2	-	27260156	NCIH2009	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.8376357262969417	[244]	[844,571,463]	9	hSpCas9	negative selection	7928744
147955356	147955379	2	+	27260156	NCIH2009	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.37466531130408876	[222]	[155,341,203]	-5	hSpCas9	negative selection	7928745
147958348	147958371	2	-	27260156	NCIH1373	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.6495230684262091	[216]	[584,315,258,106]	6	hSpCas9	negative selection	7985739
147958324	147958347	2	-	27260156	NCIH1373	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.5851781488017975	[567]	[688,716,1053,357]	6	hSpCas9	negative selection	7985740
147948155	147948178	2	+	27260156	NCIH1373	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.3383207829024626	[252]	[218,143,352,47]	-3	hSpCas9	negative selection	7985741
147948070	147948093	2	+	27260156	NCIH1373	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	0.001134302140514576	[162]	[183,152,181,56]	0	hSpCas9	negative selection	8049994
147955362	147955385	2	-	27260156	NCIH1373	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.9816496303273359	[244]	[521,526,563,144]	8	hSpCas9	negative selection	8049995
147955356	147955379	2	+	27260156	NCIH1373	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.32842683711793286	[222]	[248,133,245,46]	-3	hSpCas9	negative selection	8049996
147958348	147958371	2	-	27260156	PATU8902	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	-0.7130681162908346	[216]	[178,181,190,181]	-6	hSpCas9	negative selection	8106990
147958324	147958347	2	-	27260156	PATU8902	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.20863640660010185	[567]	[991,481,1005,1173]	2	hSpCas9	negative selection	8106991
147948155	147948178	2	+	27260156	PATU8902	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.8296910195028304	[252]	[180,70,208,344]	-6	hSpCas9	negative selection	8106992
147948070	147948093	2	+	27260156	PATU8902	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	0.3593543584806269	[162]	[358,230,253,331]	3	hSpCas9	negative selection	8171245
147955362	147955385	2	-	27260156	PATU8902	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	1.0176389906818775	[244]	[537,941,411,974]	9	hSpCas9	negative selection	8171246
147955356	147955379	2	+	27260156	PATU8902	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-1.0436524914665029	[222]	[271,239,27,83]	-7	hSpCas9	negative selection	8171247
147958348	147958371	2	-	27260156	PANC1	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.21953197565819516	[216]	[246,189,229,194]	3	hSpCas9	negative selection	8228241
147958324	147958347	2	-	27260156	PANC1	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.2847431313238752	[567]	[608,675,576,531]	4	hSpCas9	negative selection	8228242
147948155	147948178	2	+	27260156	PANC1	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.7168561699828047	[252]	[131,160,137,105]	-7	hSpCas9	negative selection	8228243
147948070	147948093	2	+	27260156	PANC1	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.7783405779156061	[162]	[44,69,140,69]	-8	hSpCas9	negative selection	8292496
147955362	147955385	2	-	27260156	PANC1	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.8611544546193072	[244]	[343,375,357,434]	9	hSpCas9	negative selection	8292497
147955356	147955379	2	+	27260156	PANC1	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.679908622046236	[222]	[151,84,102,126]	-7	hSpCas9	negative selection	8292498
147958348	147958371	2	-	27260156	PANC0813	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.11465724141086531	[216]	[437,169,228,280]	2	hSpCas9	negative selection	8349492
147958324	147958347	2	-	27260156	PANC0813	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.060370048587679026	[567]	[650,792,616,714]	1	hSpCas9	negative selection	8349493
147948155	147948178	2	+	27260156	PANC0813	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.6619281577673268	[252]	[149,197,183,213]	-7	hSpCas9	negative selection	8349494
147948070	147948093	2	+	27260156	PANC0813	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	0.05024697438565218	[162]	[242,172,220,161]	0	hSpCas9	negative selection	8413747
147955362	147955385	2	-	27260156	PANC0813	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.5861466074254142	[244]	[449,348,421,503]	8	hSpCas9	negative selection	8413748
147955356	147955379	2	+	27260156	PANC0813	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.8490113162242565	[222]	[76,285,157,58]	-8	hSpCas9	negative selection	8413749
147958348	147958371	2	-	27260156	RDES	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.21018227352457386	[216]	[159,254,373,411]	3	hSpCas9	negative selection	8470743
147958324	147958347	2	-	27260156	RDES	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.22545645390082641	[567]	[635,712,885,845]	3	hSpCas9	negative selection	8470744
147948155	147948178	2	+	27260156	RDES	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.5335884181542352	[252]	[176,232,186,201]	-7	hSpCas9	negative selection	8470745
147948070	147948093	2	+	27260156	RDES	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.12283513533894519	[162]	[160,160,208,153]	-2	hSpCas9	negative selection	8534998
147955362	147955385	2	-	27260156	RDES	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.9295291058701524	[244]	[600,493,488,529]	9	hSpCas9	negative selection	8534999
147955356	147955379	2	+	27260156	RDES	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.38203141055648104	[222]	[107,197,282,218]	-6	hSpCas9	negative selection	8535000
147958348	147958371	2	-	27260156	PC3	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.07533686623244984	[216]	[152,297,295,193]	1	hSpCas9	negative selection	8591994
147958324	147958347	2	-	27260156	PC3	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.1322362653823827	[567]	[329,836,916,571]	3	hSpCas9	negative selection	8591995
147948155	147948178	2	+	27260156	PC3	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.5028291649481016	[252]	[113,138,194,287]	-8	hSpCas9	negative selection	8591996
147948070	147948093	2	+	27260156	PC3	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.1667160527300584	[162]	[100,115,235,167]	-4	hSpCas9	negative selection	8656249
147955362	147955385	2	-	27260156	PC3	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.7782625697214021	[244]	[300,412,854,275]	9	hSpCas9	negative selection	8656250
147955356	147955379	2	+	27260156	PC3	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.12600952512098518	[222]	[98,223,397,197]	-3	hSpCas9	negative selection	8656251
147958348	147958371	2	-	27260156	PATU8988T	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.26836796883449376	[216]	[163,214,382,241]	4	hSpCas9	negative selection	8713245
147958324	147958347	2	-	27260156	PATU8988T	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.15525351342292848	[567]	[566,444,700,723]	2	hSpCas9	negative selection	8713246
147948155	147948178	2	+	27260156	PATU8988T	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.45283611963261183	[252]	[148,178,207,177]	-6	hSpCas9	negative selection	8713247
147948070	147948093	2	+	27260156	PATU8988T	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-1.0051116272022598	[162]	[90,51,101,64]	-8	hSpCas9	negative selection	8777500
147955362	147955385	2	-	27260156	PATU8988T	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	1.0466162849760865	[244]	[391,408,550,604]	9	hSpCas9	negative selection	8777501
147955356	147955379	2	+	27260156	PATU8988T	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.2883793404993975	[222]	[297,240,59,108]	-5	hSpCas9	negative selection	8777502
147958348	147958371	2	-	27260156	T47D	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.32371518273087463	[216]	[247,356,324,331]	7	hSpCas9	negative selection	8834496
147958324	147958347	2	-	27260156	T47D	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.3263050487231285	[567]	[885,806,798,828]	7	hSpCas9	negative selection	8834497
147948155	147948178	2	+	27260156	T47D	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.5580907398547461	[252]	[180,219,195,201]	-8	hSpCas9	negative selection	8834498
147948070	147948093	2	+	27260156	T47D	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	0.136999600211549	[162]	[150,215,247,218]	3	hSpCas9	negative selection	8898751
147955362	147955385	2	-	27260156	T47D	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.7698085919571986	[244]	[543,434,489,481]	9	hSpCas9	negative selection	8898752
147955356	147955379	2	+	27260156	T47D	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.07578944400103294	[222]	[284,165,280,260]	-2	hSpCas9	negative selection	8898753
147958348	147958371	2	-	27260156	SU8686	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.4304308551303935	[216]	[309,348,213,268]	7	hSpCas9	negative selection	8955747
147958324	147958347	2	-	27260156	SU8686	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.2711485983319041	[567]	[702,554,716,766]	4	hSpCas9	negative selection	8955748
147948155	147948178	2	+	27260156	SU8686	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.3048255684005481	[252]	[177,144,196,319]	-5	hSpCas9	negative selection	8955749
147948070	147948093	2	+	27260156	SU8686	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.13842926930398902	[162]	[139,161,170,105]	-2	hSpCas9	negative selection	9020002
147955362	147955385	2	-	27260156	SU8686	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.8956794603627926	[244]	[376,514,490,416]	9	hSpCas9	negative selection	9020003
147955356	147955379	2	+	27260156	SU8686	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.4767294288285846	[222]	[134,162,242,85]	-6	hSpCas9	negative selection	9020004
147958348	147958371	2	-	27260156	SKES1	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.17782082975936042	[216]	[244,228,226,270]	4	hSpCas9	negative selection	9076998
147958324	147958347	2	-	27260156	SKES1	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.02614626705782047	[567]	[792,639,430,487]	0	hSpCas9	negative selection	9076999
147948155	147948178	2	+	27260156	SKES1	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.5152962981046245	[252]	[131,193,248,129]	-8	hSpCas9	negative selection	9077000
147948070	147948093	2	+	27260156	SKES1	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.035633870626685216	[162]	[259,104,158,120]	-1	hSpCas9	negative selection	9141253
147955362	147955385	2	-	27260156	SKES1	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.6173537813841736	[244]	[359,342,470,320]	9	hSpCas9	negative selection	9141254
147955356	147955379	2	+	27260156	SKES1	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.45312244366352616	[222]	[101,209,155,175]	-7	hSpCas9	negative selection	9141255
147958348	147958371	2	-	27260156	TOV112D	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	-0.2571923335983497	[216]	[195,220,141,178]	-5	hSpCas9	negative selection	9198249
147958324	147958347	2	-	27260156	TOV112D	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.02292049831829046	[567]	[463,451,616,732]	0	hSpCas9	negative selection	9198250
147948155	147948178	2	+	27260156	TOV112D	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.3036746967803259	[252]	[177,241,253,154]	-5	hSpCas9	negative selection	9198251
147948070	147948093	2	+	27260156	TOV112D	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	0.3820022995566561	[162]	[114,410,145,218]	7	hSpCas9	negative selection	9262504
147955362	147955385	2	-	27260156	TOV112D	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.8180169911353401	[244]	[654,499,249,361]	9	hSpCas9	negative selection	9262505
147955356	147955379	2	+	27260156	TOV112D	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.43297991683560166	[222]	[108,158,143,240]	-7	hSpCas9	negative selection	9262506
147958348	147958371	2	-	27260156	TC71	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.09153258419433596	[216]	[188,254,318,225]	2	hSpCas9	negative selection	9319500
147958324	147958347	2	-	27260156	TC71	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.10712852754660535	[567]	[788,499,659,671]	2	hSpCas9	negative selection	9319501
147948155	147948178	2	+	27260156	TC71	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.4094555964471902	[252]	[171,161,207,279]	-8	hSpCas9	negative selection	9319502
147948070	147948093	2	+	27260156	TC71	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.07860010243372773	[162]	[138,200,183,135]	-2	hSpCas9	negative selection	9383755
147955362	147955385	2	-	27260156	TC71	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	0.6888691140452887	[244]	[474,331,420,466]	9	hSpCas9	negative selection	9383756
147955356	147955379	2	+	27260156	TC71	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	-0.07844462235374006	[222]	[184,213,226,283]	-2	hSpCas9	negative selection	9383757
147958348	147958371	2	-	27260156	TC32	viability	CAATGACAAAATCGCCCTAAAGG	ORC4	ENSG00000115947	0.18939853689541397	[216]	[138,131,366,360]	3	hSpCas9	negative selection	9440751
147958324	147958347	2	-	27260156	TC32	viability	AATCACAAGGCAGTTAAATCTGG	ORC4	ENSG00000115947	0.07060101466293683	[567]	[590,335,652,736]	1	hSpCas9	negative selection	9440752
147948155	147948178	2	+	27260156	TC32	viability	AATTCATTAAGTGTATCTGCCGG	ORC4	ENSG00000115947	-0.36958112223161343	[252]	[268,82,267,144]	-6	hSpCas9	negative selection	9440753
147948070	147948093	2	+	27260156	TC32	viability	TTCTCAGCAAAAACCTTGTCTGG	ORC4	ENSG00000115947	-0.23542711166739183	[162]	[145,64,212,125]	-4	hSpCas9	negative selection	9505006
147955362	147955385	2	-	27260156	TC32	viability	TGAAAACCTTTCATTTCTTCTGG	ORC4	ENSG00000115947	1.1533245121705096	[244]	[411,424,708,553]	9	hSpCas9	negative selection	9505007
147955356	147955379	2	+	27260156	TC32	viability	AAGCTTCCAGAAGAAATGAAAGG	ORC4	ENSG00000115947	0.20145562930156902	[222]	[187,322,250,156]	3	hSpCas9	negative selection	9505008
147943438	147943461	2	+	27869803	HPAFII	viability after 27 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.8968768953726142	[188]	[108,6,NaN]	-6	hSpCas9	negative selection	9571837
147958337	147958360	2	-	27869803	HPAFII	viability after 27 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-1.0485289254162753	[195]	[3,87,NaN]	-6	hSpCas9	negative selection	9571838
147943438	147943461	2	+	27869803	HPAFII	viability after 15 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.4814114404778771	[188]	[245,82,NaN]	-5	hSpCas9	negative selection	9654286
147958337	147958360	2	-	27869803	HPAFII	viability after 15 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-1.748745973286026	[195]	[29,82,NaN]	-9	hSpCas9	negative selection	9654287
147943438	147943461	2	+	27869803	ASPC1	viability after 36 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.37196458116153386	[420]	[76,200,258]	4	hSpCas9	negative selection	9736735
147958337	147958360	2	-	27869803	ASPC1	viability after 36 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-0.7356338952703005	[377]	[114,124,16]	-6	hSpCas9	negative selection	9736736
147943438	147943461	2	+	27869803	PATU8988S	viability after 35 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.6975762118918014	[289]	[79,63,NaN]	-6	hSpCas9	negative selection	9819184
147958337	147958360	2	-	27869803	PATU8988S	viability after 35 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-2.2078764290052253	[354]	[7,53,NaN]	-9	hSpCas9	negative selection	9819185
147943438	147943461	2	+	27869803	PATU8988S	viability after 31 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.3616615022297731	[289]	[67,117,NaN]	-4	hSpCas9	negative selection	9901633
147958337	147958360	2	-	27869803	PATU8988S	viability after 31 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-2.2461902711048114	[354]	[13,49,NaN]	-9	hSpCas9	negative selection	9901634
147943438	147943461	2	+	27869803	HPAFII	viability after 35 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-1.1376692582733798	[188]	[74,7,NaN]	-6	hSpCas9	negative selection	9984082
147958337	147958360	2	-	27869803	HPAFII	viability after 35 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-2.224908492940068	[195]	[0,43,NaN]	-8	hSpCas9	negative selection	9984083
147943438	147943461	2	+	27869803	HPAFII	viability after 31 days	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.8923699568286941	[188]	[104,4,NaN]	-5	hSpCas9	negative selection	10066531
147958337	147958360	2	-	27869803	HPAFII	viability after 31 days	TCGCCCTAAAGGAAATCACAAGG	ORC4	ENSG00000115947	-2.3181646241168363	[195]	[0,44,NaN]	-8	hSpCas9	negative selection	10066532
147943438	147943461	2	+	28162770	P31FUJ	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.3854761628056669	[238]	[214]	-3	hSpCas9	negative selection	10205037
147972774	147972797	2	+	28162770	P31FUJ	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-1.8300430349139714	[235]	[77]	-8	hSpCas9	negative selection	10205038
147948082	147948105	2	+	28162770	P31FUJ	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	-0.2795964158933197	[281]	[272]	-3	hSpCas9	negative selection	10205039
147939193	147939216	2	+	28162770	P31FUJ	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.12819545515157593	[101]	[130]	1	hSpCas9	negative selection	10205040
147935537	147935560	2	-	28162770	P31FUJ	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-2.2561851318523294	[621]	[152]	-8	hSpCas9	negative selection	10205041
147935516	147935539	2	-	28162770	P31FUJ	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	0.5350243534565879	[36]	[62]	6	hSpCas9	negative selection	10205042
147935543	147935566	2	-	28162770	P31FUJ	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-3.518204423276627	[194]	[19]	-9	hSpCas9	negative selection	10205043
147935535	147935558	2	+	28162770	P31FUJ	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	-0.48817194819709936	[412]	[345]	-4	hSpCas9	negative selection	10205044
147972755	147972778	2	-	28162770	P31FUJ	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-3.5349218182215605	[433]	[43]	-9	hSpCas9	negative selection	10205045
147972791	147972814	2	-	28162770	P31FUJ	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-2.354652463852828	[604]	[138]	-8	hSpCas9	negative selection	10205046
147943438	147943461	2	+	28162770	TF1	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	NaN	[NaN]	[148]	1	hSpCas9	negative selection	10374403
147972774	147972797	2	+	28162770	TF1	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10374404
147948082	147948105	2	+	28162770	TF1	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	NaN	[NaN]	[47]	1	hSpCas9	negative selection	10374405
147939193	147939216	2	+	28162770	TF1	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	NaN	[NaN]	[179]	1	hSpCas9	negative selection	10374406
147935537	147935560	2	-	28162770	TF1	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	NaN	[NaN]	[342]	1	hSpCas9	negative selection	10374407
147935516	147935539	2	-	28162770	TF1	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10374408
147935543	147935566	2	-	28162770	TF1	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10374409
147935535	147935558	2	+	28162770	TF1	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	NaN	[NaN]	[197]	1	hSpCas9	negative selection	10374410
147972755	147972778	2	-	28162770	TF1	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	NaN	[NaN]	[68]	1	hSpCas9	negative selection	10374411
147972791	147972814	2	-	28162770	TF1	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	NaN	[NaN]	[166]	1	hSpCas9	negative selection	10374412
147943438	147943461	2	+	28162770	SKM1	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.2951818413483335	[64]	[140]	3	hSpCas9	negative selection	10543769
147972774	147972797	2	+	28162770	SKM1	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-0.24649952654991572	[50]	[75]	-2	hSpCas9	negative selection	10543770
147948082	147948105	2	+	28162770	SKM1	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	-0.631670485917856	[77]	[88]	-5	hSpCas9	negative selection	10543771
147939193	147939216	2	+	28162770	SKM1	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.17799830197799438	[28]	[57]	1	hSpCas9	negative selection	10543772
147935537	147935560	2	-	28162770	SKM1	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-1.8648147815609786	[170]	[82]	-8	hSpCas9	negative selection	10543773
147935516	147935539	2	-	28162770	SKM1	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	0.5930358012568382	[8]	[23]	6	hSpCas9	negative selection	10543774
147935543	147935566	2	-	28162770	SKM1	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-3.0546624548122807	[46]	[9]	-9	hSpCas9	negative selection	10543775
147935535	147935558	2	+	28162770	SKM1	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	-0.2814333166593027	[98]	[143]	-2	hSpCas9	negative selection	10543776
147972755	147972778	2	-	28162770	SKM1	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-4.851749041416057	[97]	[5]	-9	hSpCas9	negative selection	10543777
147972791	147972814	2	-	28162770	SKM1	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-2.720122084002792	[122]	[32]	-9	hSpCas9	negative selection	10543778
147943438	147943461	2	+	28162770	SKM1	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.2951818413483335	[64]	[140]	3	hSpCas9	negative selection	10713135
147972774	147972797	2	+	28162770	SKM1	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-0.24649952654991572	[50]	[75]	-2	hSpCas9	negative selection	10713136
147948082	147948105	2	+	28162770	SKM1	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	-0.631670485917856	[77]	[88]	-5	hSpCas9	negative selection	10713137
147939193	147939216	2	+	28162770	SKM1	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.17799830197799438	[28]	[57]	1	hSpCas9	negative selection	10713138
147935537	147935560	2	-	28162770	SKM1	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-1.8648147815609786	[170]	[82]	-8	hSpCas9	negative selection	10713139
147935516	147935539	2	-	28162770	SKM1	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	0.5930358012568382	[8]	[23]	6	hSpCas9	negative selection	10713140
147935543	147935566	2	-	28162770	SKM1	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-3.0546624548122807	[46]	[9]	-9	hSpCas9	negative selection	10713141
147935535	147935558	2	+	28162770	SKM1	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	-0.2814333166593027	[98]	[143]	-2	hSpCas9	negative selection	10713142
147972755	147972778	2	-	28162770	SKM1	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-4.851749041416057	[97]	[5]	-9	hSpCas9	negative selection	10713143
147972791	147972814	2	-	28162770	SKM1	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-2.720122084002792	[122]	[32]	-9	hSpCas9	negative selection	10713144
147943438	147943461	2	+	28162770	PL21	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.056553264470646986	[226]	[94]	0	hSpCas9	negative selection	10882501
147972774	147972797	2	+	28162770	PL21	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-3.150357632594813	[203]	[9]	-9	hSpCas9	negative selection	10882502
147948082	147948105	2	+	28162770	PL21	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	0.2879155745777608	[270]	[143]	2	hSpCas9	negative selection	10882503
147939193	147939216	2	+	28162770	PL21	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.02730301762710463	[123]	[54]	0	hSpCas9	negative selection	10882504
147935537	147935560	2	-	28162770	PL21	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-1.761386237696044	[591]	[75]	-8	hSpCas9	negative selection	10882505
147935516	147935539	2	-	28162770	PL21	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	0.6282332665936101	[54]	[36]	5	hSpCas9	negative selection	10882506
147935543	147935566	2	-	28162770	PL21	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-4.434066405251686	[148]	[2]	-9	hSpCas9	negative selection	10882507
147935535	147935558	2	+	28162770	PL21	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	-0.8653342229879613	[292]	[69]	-5	hSpCas9	negative selection	10882508
147972755	147972778	2	-	28162770	PL21	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-2.403931709179541	[303]	[24]	-8	hSpCas9	negative selection	10882509
147972791	147972814	2	-	28162770	PL21	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-2.628379917566326	[411]	[28]	-9	hSpCas9	negative selection	10882510
147943438	147943461	2	+	28162770	P31FUJ	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.3854761628056669	[238]	[214]	-3	hSpCas9	negative selection	11051867
147972774	147972797	2	+	28162770	P31FUJ	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-1.8300430349139714	[235]	[77]	-8	hSpCas9	negative selection	11051868
147948082	147948105	2	+	28162770	P31FUJ	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	-0.2795964158933197	[281]	[272]	-3	hSpCas9	negative selection	11051869
147939193	147939216	2	+	28162770	P31FUJ	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.12819545515157593	[101]	[130]	1	hSpCas9	negative selection	11051870
147935537	147935560	2	-	28162770	P31FUJ	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-2.2561851318523294	[621]	[152]	-8	hSpCas9	negative selection	11051871
147935516	147935539	2	-	28162770	P31FUJ	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	0.5350243534565879	[36]	[62]	6	hSpCas9	negative selection	11051872
147935543	147935566	2	-	28162770	P31FUJ	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-3.518204423276627	[194]	[19]	-9	hSpCas9	negative selection	11051873
147935535	147935558	2	+	28162770	P31FUJ	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	-0.48817194819709936	[412]	[345]	-4	hSpCas9	negative selection	11051874
147972755	147972778	2	-	28162770	P31FUJ	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-3.5349218182215605	[433]	[43]	-9	hSpCas9	negative selection	11051875
147972791	147972814	2	-	28162770	P31FUJ	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-2.354652463852828	[604]	[138]	-8	hSpCas9	negative selection	11051876
147943438	147943461	2	+	28162770	OCIAML5	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.5332443868444563	[92]	[115]	-4	hSpCas9	negative selection	11221233
147972774	147972797	2	+	28162770	OCIAML5	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-1.5369705094590598	[126]	[78]	-7	hSpCas9	negative selection	11221234
147948082	147948105	2	+	28162770	OCIAML5	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	-0.15895526628721823	[166]	[269]	-1	hSpCas9	negative selection	11221235
147939193	147939216	2	+	28162770	OCIAML5	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	1.254132832967928	[35]	[154]	9	hSpCas9	negative selection	11221236
147935537	147935560	2	-	28162770	OCIAML5	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-2.0676296538103287	[280]	[120]	-8	hSpCas9	negative selection	11221237
147935516	147935539	2	-	28162770	OCIAML5	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	0.7328959298571593	[39]	[119]	6	hSpCas9	negative selection	11221238
147935543	147935566	2	-	28162770	OCIAML5	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-4.061519936492947	[110]	[11]	-9	hSpCas9	negative selection	11221239
147935535	147935558	2	+	28162770	OCIAML5	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	-0.520033598340239	[312]	[393]	-4	hSpCas9	negative selection	11221240
147972755	147972778	2	-	28162770	OCIAML5	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-3.269678013806667	[186]	[34]	-9	hSpCas9	negative selection	11221241
147972791	147972814	2	-	28162770	OCIAML5	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	0.23566227850747778	[318]	[677]	2	hSpCas9	negative selection	11221242
147943438	147943461	2	+	28162770	EOL1	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.5238655652687607	[399]	[302]	5	hSpCas9	negative selection	11390599
147972774	147972797	2	+	28162770	EOL1	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-2.781721025372755	[247]	[18]	-9	hSpCas9	negative selection	11390600
147948082	147948105	2	+	28162770	EOL1	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	-0.9178025718432733	[458]	[127]	-6	hSpCas9	negative selection	11390601
147939193	147939216	2	+	28162770	EOL1	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.7797312187187537	[177]	[160]	7	hSpCas9	negative selection	11390602
147935537	147935560	2	-	28162770	EOL1	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-0.9909187182177975	[927]	[245]	-6	hSpCas9	negative selection	11390603
147935516	147935539	2	-	28162770	EOL1	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	0.6539001816268655	[75]	[62]	6	hSpCas9	negative selection	11390604
147935543	147935566	2	-	28162770	EOL1	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-3.171376648428001	[170]	[9]	-9	hSpCas9	negative selection	11390605
147935535	147935558	2	+	28162770	EOL1	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	0.35750717884664074	[439]	[296]	3	hSpCas9	negative selection	11390606
147972755	147972778	2	-	28162770	EOL1	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-1.314239088016582	[353]	[74]	-7	hSpCas9	negative selection	11390607
147972791	147972814	2	-	28162770	EOL1	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-1.9948337682211807	[521]	[68]	-8	hSpCas9	negative selection	11390608
147943438	147943461	2	+	28162770	MOLM13	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.41524790180334914	[306]	[295]	3	hSpCas9	negative selection	11559965
147972774	147972797	2	+	28162770	MOLM13	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-2.5048032724596863	[313]	[39]	-8	hSpCas9	negative selection	11559966
147948082	147948105	2	+	28162770	MOLM13	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	-0.9771103557501324	[372]	[136]	-5	hSpCas9	negative selection	11559967
147939193	147939216	2	+	28162770	MOLM13	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.8002448478822792	[192]	[242]	6	hSpCas9	negative selection	11559968
147935537	147935560	2	-	28162770	MOLM13	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-1.2149204425747222	[731]	[227]	-6	hSpCas9	negative selection	11559969
147935516	147935539	2	-	28162770	MOLM13	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	-4.406579736371562	[87]	[2]	-9	hSpCas9	negative selection	11559970
147935543	147935566	2	-	28162770	MOLM13	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-1.7471235094262716	[194]	[41]	-7	hSpCas9	negative selection	11559971
147935535	147935558	2	+	28162770	MOLM13	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	-1.7753267373287427	[534]	[112]	-7	hSpCas9	negative selection	11559972
147972755	147972778	2	-	28162770	MOLM13	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-4.232550336596513	[337]	[12]	-9	hSpCas9	negative selection	11559973
147972791	147972814	2	-	28162770	MOLM13	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-2.0236695573692765	[612]	[108]	-7	hSpCas9	negative selection	11559974
147943438	147943461	2	+	28162770	HEL	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.6853831694088506	[299]	[308]	6	hSpCas9	negative selection	11729331
147972774	147972797	2	+	28162770	HEL	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-0.9626877712805149	[212]	[69]	-5	hSpCas9	negative selection	11729332
147948082	147948105	2	+	28162770	HEL	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	0.6052641265816942	[311]	[303]	5	hSpCas9	negative selection	11729333
147939193	147939216	2	+	28162770	HEL	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	1.746243407754217	[120]	[259]	9	hSpCas9	negative selection	11729334
147935537	147935560	2	-	28162770	HEL	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	0.20248134273223606	[653]	[481]	1	hSpCas9	negative selection	11729335
147935516	147935539	2	-	28162770	HEL	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	1.028797264307435	[87]	[114]	8	hSpCas9	negative selection	11729336
147935543	147935566	2	-	28162770	HEL	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-0.6185264809803812	[162]	[67]	-4	hSpCas9	negative selection	11729337
147935535	147935558	2	+	28162770	HEL	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	-1.1215473681653612	[461]	[135]	-6	hSpCas9	negative selection	11729338
147972755	147972778	2	-	28162770	HEL	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-6.552018022421891	[292]	[1]	-9	hSpCas9	negative selection	11729339
147972791	147972814	2	-	28162770	HEL	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-1.1876179154188629	[568]	[159]	-6	hSpCas9	negative selection	11729340
147943438	147943461	2	+	28162770	MV411	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.407065883191458	[254]	[161]	-3	hSpCas9	negative selection	11898697
147972774	147972797	2	+	28162770	MV411	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-0.7895566566994264	[157]	[76]	-5	hSpCas9	negative selection	11898698
147948082	147948105	2	+	28162770	MV411	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	0.4914888532489963	[254]	[301]	4	hSpCas9	negative selection	11898699
147939193	147939216	2	+	28162770	MV411	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-0.12953190766254885	[186]	[143]	-1	hSpCas9	negative selection	11898700
147935537	147935560	2	-	28162770	MV411	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-0.4833758164018356	[623]	[375]	-4	hSpCas9	negative selection	11898701
147935516	147935539	2	-	28162770	MV411	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	2.108461137633965	[48]	[177]	9	hSpCas9	negative selection	11898702
147935543	147935566	2	-	28162770	MV411	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-0.8080575618089283	[105]	[50]	-5	hSpCas9	negative selection	11898703
147935535	147935558	2	+	28162770	MV411	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	0.27688132867525705	[290]	[296]	2	hSpCas9	negative selection	11898704
147972755	147972778	2	-	28162770	MV411	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-2.4508245140529468	[330]	[50]	-8	hSpCas9	negative selection	11898705
147972791	147972814	2	-	28162770	MV411	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-1.508893368250362	[374]	[110]	-7	hSpCas9	negative selection	11898706
147943438	147943461	2	+	28162770	MONOMAC1	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.5776408492745237	[137]	[105]	-5	hSpCas9	negative selection	12068063
147972774	147972797	2	+	28162770	MONOMAC1	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-0.6236623206136096	[124]	[92]	-5	hSpCas9	negative selection	12068064
147948082	147948105	2	+	28162770	MONOMAC1	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	-0.10028361417996617	[172]	[184]	-1	hSpCas9	negative selection	12068065
147939193	147939216	2	+	28162770	MONOMAC1	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	0.9275082508787498	[60]	[132]	8	hSpCas9	negative selection	12068066
147935537	147935560	2	-	28162770	MONOMAC1	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-1.3282813803378062	[367]	[167]	-7	hSpCas9	negative selection	12068067
147935516	147935539	2	-	28162770	MONOMAC1	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	-3.6120743463383977	[31]	[2]	-9	hSpCas9	negative selection	12068068
147935543	147935566	2	-	28162770	MONOMAC1	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-3.090121643143042	[103]	[13]	-9	hSpCas9	negative selection	12068069
147935535	147935558	2	+	28162770	MONOMAC1	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	-0.9195028715306448	[197]	[119]	-6	hSpCas9	negative selection	12068070
147972755	147972778	2	-	28162770	MONOMAC1	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-2.458529088084942	[186]	[38]	-9	hSpCas9	negative selection	12068071
147972791	147972814	2	-	28162770	MONOMAC1	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-1.5349064858159378	[272]	[107]	-8	hSpCas9	negative selection	12068072
147943438	147943461	2	+	28162770	OCIAML2	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	0.519316510093916	[35]	[285]	5	hSpCas9	negative selection	12237429
147972774	147972797	2	+	28162770	OCIAML2	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-2.711637924745956	[38]	[32]	-9	hSpCas9	negative selection	12237430
147948082	147948105	2	+	28162770	OCIAML2	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	-0.687121645138925	[60]	[209]	-5	hSpCas9	negative selection	12237431
147939193	147939216	2	+	28162770	OCIAML2	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-0.49200347603472827	[33]	[133]	-4	hSpCas9	negative selection	12237432
147935537	147935560	2	-	28162770	OCIAML2	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-1.2724037150364658	[128]	[295]	-7	hSpCas9	negative selection	12237433
147935516	147935539	2	-	28162770	OCIAML2	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	-0.7336642310759551	[14]	[49]	-5	hSpCas9	negative selection	12237434
147935543	147935566	2	-	28162770	OCIAML2	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	-1.608133348992096	[21]	[39]	-7	hSpCas9	negative selection	12237435
147935535	147935558	2	+	28162770	OCIAML2	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	0.45121111183232887	[63]	[484]	4	hSpCas9	negative selection	12237436
147972755	147972778	2	-	28162770	OCIAML2	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-3.4991989774389323	[50]	[24]	-9	hSpCas9	negative selection	12237437
147972791	147972814	2	-	28162770	OCIAML2	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-2.594365193664406	[72]	[66]	-8	hSpCas9	negative selection	12237438
147943438	147943461	2	+	28162770	OCIAML3	viability	ATAGCATGTGTAATGACCGCAGG	ORC4	ENSG00000115947	-0.1287153702656234	[66]	[184]	-1	hSpCas9	negative selection	12406795
147972774	147972797	2	+	28162770	OCIAML3	viability	GGACAGAGTTACTCTCTCCATGG	ORC4	ENSG00000115947	-1.0269670476002695	[53]	[79]	-6	hSpCas9	negative selection	12406796
147948082	147948105	2	+	28162770	OCIAML3	viability	ACCTTGTCTGGAAACTCTGCAGG	ORC4	ENSG00000115947	-0.43050890804128356	[74]	[167]	-3	hSpCas9	negative selection	12406797
147939193	147939216	2	+	28162770	OCIAML3	viability	AGATCTACGGCAGTCATAAATGG	ORC4	ENSG00000115947	-1.2653848928627927	[42]	[53]	-7	hSpCas9	negative selection	12406798
147935537	147935560	2	-	28162770	OCIAML3	viability	GTCCTACAGATGTGAGGCAGTGG	ORC4	ENSG00000115947	-1.3716152189877153	[197]	[230]	-7	hSpCas9	negative selection	12406799
147935516	147935539	2	-	28162770	OCIAML3	viability	GGGCAACATCCTCACTAAGCTGG	ORC4	ENSG00000115947	-0.25840460853972447	[20]	[52]	-2	hSpCas9	negative selection	12406800
147935543	147935566	2	-	28162770	OCIAML3	viability	CCAACTGTCCTACAGATGTGAGG	ORC4	ENSG00000115947	0.19855027980536033	[27]	[96]	2	hSpCas9	negative selection	12406801
147935535	147935558	2	+	28162770	OCIAML3	viability	GCCCACTGCCTCACATCTGTAGG	ORC4	ENSG00000115947	-0.1852020947568339	[86]	[230]	-1	hSpCas9	negative selection	12406802
147972755	147972778	2	-	28162770	OCIAML3	viability	GTCCTTATTATCGGACCCCGAGG	ORC4	ENSG00000115947	-2.079434467494405	[97]	[69]	-8	hSpCas9	negative selection	12406803
147972791	147972814	2	-	28162770	OCIAML3	viability	CTGAAAAGAACTGCTCTCCATGG	ORC4	ENSG00000115947	-2.8956633401852647	[105]	[42]	-9	hSpCas9	negative selection	12406804