Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5053
• Symbol: PAH
• Description: phenylalanine hydroxylase

DataSource: http://genomecrispr.dkfz.de/#!/results/PAH

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
102917104	102917127	12	+	26472758	Jiyoye	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	0.3639221835519896	[236]	[229]	2	hSpCas9	negative selection	115461
102917070	102917093	12	-	26472758	Jiyoye	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	-0.03385732630591498	[223]	[164]	0	hSpCas9	negative selection	115462
102877482	102877505	12	-	26472758	Jiyoye	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	0.6819322723642084	[142]	[172]	5	hSpCas9	negative selection	115463
102917085	102917108	12	+	26472758	Jiyoye	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	-0.1717633315875129	[238]	[159]	-1	hSpCas9	negative selection	115464
102894876	102894899	12	+	26472758	Jiyoye	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.3113153660983574	[279]	[261]	2	hSpCas9	negative selection	115465
102852912	102852935	12	+	26472758	Jiyoye	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	-0.3481395225392247	[210]	[124]	-2	hSpCas9	negative selection	115466
102852886	102852909	12	+	26472758	Jiyoye	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.13318176368221313	[184]	[152]	1	hSpCas9	negative selection	115467
102843727	102843750	12	+	26472758	Jiyoye	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	-0.07014639602731298	[141]	[101]	0	hSpCas9	negative selection	115468
102840455	102840478	12	-	26472758	Jiyoye	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	-0.8748599862579762	[213]	[87]	-6	hSpCas9	negative selection	115469
102917118	102917141	12	-	26472758	Jiyoye	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	1.2207622572749919	[32]	[57]	7	hSpCas9	negative selection	115470
102917104	102917127	12	+	26472758	KBM7	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	0.6011600709483638	[621,390]	[418,296]	6	hSpCas9	negative selection	306579
102917070	102917093	12	-	26472758	KBM7	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.43169601420497483	[826,764]	[386,610]	4	hSpCas9	negative selection	306580
102877482	102877505	12	-	26472758	KBM7	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	-0.07539575250198255	[494,457]	[234,192]	0	hSpCas9	negative selection	306581
102917085	102917108	12	+	26472758	KBM7	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	0.26697471322658395	[785,543]	[350,388]	2	hSpCas9	negative selection	306582
102894876	102894899	12	+	26472758	KBM7	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.4741045421307044	[1126,972]	[712,657]	5	hSpCas9	negative selection	306583
102852912	102852935	12	+	26472758	KBM7	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	0.3086812845461817	[698,433]	[377,274]	3	hSpCas9	negative selection	306584
102852886	102852909	12	+	26472758	KBM7	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.606182092702634	[759,529]	[455,454]	6	hSpCas9	negative selection	306585
102843727	102843750	12	+	26472758	KBM7	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	0.43366336956520396	[697,617]	[420,413]	4	hSpCas9	negative selection	306586
102840455	102840478	12	-	26472758	KBM7	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	0.06479348273286467	[687,664]	[385,286]	0	hSpCas9	negative selection	306587
102917118	102917141	12	-	26472758	KBM7	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	0.36767919191334436	[392,328]	[206,227]	4	hSpCas9	negative selection	306588
102917104	102917127	12	+	26472758	Raji	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	0.5515673803119598	[293]	[99]	5	hSpCas9	negative selection	497697
102917070	102917093	12	-	26472758	Raji	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.3951858463563356	[461]	[140]	4	hSpCas9	negative selection	497698
102877482	102877505	12	-	26472758	Raji	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	-0.24568307132266692	[280]	[54]	-2	hSpCas9	negative selection	497699
102917085	102917108	12	+	26472758	Raji	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	1.0480049882946676	[247]	[118]	8	hSpCas9	negative selection	497700
102894876	102894899	12	+	26472758	Raji	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.4731775156325939	[446]	[143]	4	hSpCas9	negative selection	497701
102852912	102852935	12	+	26472758	Raji	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	0.7068456057898709	[263]	[99]	6	hSpCas9	negative selection	497702
102852886	102852909	12	+	26472758	Raji	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.12343147660546938	[446]	[112]	1	hSpCas9	negative selection	497703
102843727	102843750	12	+	26472758	Raji	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	0.054434655424640654	[443]	[106]	0	hSpCas9	negative selection	497704
102840455	102840478	12	-	26472758	Raji	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	0.4281707088563922	[252]	[78]	4	hSpCas9	negative selection	497705
102917118	102917141	12	-	26472758	Raji	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	1.4915270267066596	[117]	[76]	9	hSpCas9	negative selection	497706
102917104	102917127	12	+	26472758	K562	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	0.17010040697661333	[477]	[453]	1	hSpCas9	negative selection	688815
102917070	102917093	12	-	26472758	K562	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.5672454180614581	[641]	[802]	4	hSpCas9	negative selection	688816
102877482	102877505	12	-	26472758	K562	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	0.272057408988727	[516]	[526]	2	hSpCas9	negative selection	688817
102917085	102917108	12	+	26472758	K562	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	0.6607530315637429	[555]	[741]	5	hSpCas9	negative selection	688818
102894876	102894899	12	+	26472758	K562	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.6414663023576042	[927]	[1221]	5	hSpCas9	negative selection	688819
102852912	102852935	12	+	26472758	K562	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	0.49583676199228033	[477]	[568]	4	hSpCas9	negative selection	688820
102852886	102852909	12	+	26472758	K562	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.13456224843781223	[490]	[454]	1	hSpCas9	negative selection	688821
102843727	102843750	12	+	26472758	K562	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	-0.9550670223663298	[603]	[262]	-5	hSpCas9	negative selection	688822
102840455	102840478	12	-	26472758	K562	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	-0.12170917113145044	[463]	[359]	-1	hSpCas9	negative selection	688823
102917118	102917141	12	-	26472758	K562	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	0.4676320281379227	[250]	[292]	4	hSpCas9	negative selection	688824
102852864	102852887	12	+	26627737	DLD1	viability	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	-0.23242168108122696	[118]	[54,1,35]	-2	hSpCas9	negative selection	781798
102855310	102855333	12	-	26627737	DLD1	viability	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	0.12310632534212829	[978]	[491,181,320]	1	hSpCas9	negative selection	781799
102866629	102866652	12	+	26627737	DLD1	viability	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.4548894237100595	[468]	[107,302,196]	4	hSpCas9	negative selection	781800
102877446	102877469	12	+	26627737	DLD1	viability	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	0.3203159972323959	[923]	[296,456,335]	3	hSpCas9	negative selection	781801
102894822	102894845	12	+	26627737	DLD1	viability	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.8324780594760343	[253]	[150,132,139]	7	hSpCas9	negative selection	781802
102917070	102917093	12	-	26627737	DLD1	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.3524950180409542	[247]	[77,103,112]	3	hSpCas9	negative selection	781803
102852864	102852887	12	+	26627737	GBM cells	viability after 5 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	0.776057127100152	[48]	[52,36]	9	hSpCas9	negative selection	864113
102855310	102855333	12	-	26627737	GBM cells	viability after 5 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-1.0720464521629607	[540]	[127,147]	-9	hSpCas9	negative selection	864114
102866629	102866652	12	+	26627737	GBM cells	viability after 5 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.7651153768182262	[174]	[161,156]	8	hSpCas9	negative selection	864115
102877446	102877469	12	+	26627737	GBM cells	viability after 5 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	-0.3140798484485128	[509]	[210,228]	-5	hSpCas9	negative selection	864116
102894822	102894845	12	+	26627737	GBM cells	viability after 5 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.9818068832340304	[185]	[218,174]	9	hSpCas9	negative selection	864117
102917070	102917093	12	-	26627737	GBM cells	viability after 5 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.6559870425004666	[170]	[177,110]	8	hSpCas9	negative selection	864118
102852864	102852887	12	+	26627737	GBM cells	viability after 13 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	0.2236413015600558	[48]	[51,13]	3	hSpCas9	negative selection	946428
102855310	102855333	12	-	26627737	GBM cells	viability after 13 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-1.088780335577654	[540]	[153,124]	-8	hSpCas9	negative selection	946429
102866629	102866652	12	+	26627737	GBM cells	viability after 13 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.9183183017768254	[174]	[179,178]	9	hSpCas9	negative selection	946430
102877446	102877469	12	+	26627737	GBM cells	viability after 13 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	-0.4056019434538467	[509]	[209,207]	-5	hSpCas9	negative selection	946431
102894822	102894845	12	+	26627737	GBM cells	viability after 13 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.9926231648727253	[185]	[159,233]	9	hSpCas9	negative selection	946432
102917070	102917093	12	-	26627737	GBM cells	viability after 13 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.036337764322080024	[170]	[114,78]	0	hSpCas9	negative selection	946433
102852864	102852887	12	+	26627737	GBM cells	viability after 21 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	-0.5232912518428079	[48]	[17,18]	-5	hSpCas9	negative selection	1028743
102855310	102855333	12	-	26627737	GBM cells	viability after 21 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-1.3461152359181348	[540]	[112,117]	-8	hSpCas9	negative selection	1028744
102866629	102866652	12	+	26627737	GBM cells	viability after 21 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.8387902497997672	[174]	[168,170]	8	hSpCas9	negative selection	1028745
102877446	102877469	12	+	26627737	GBM cells	viability after 21 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	-0.345200681219341	[509]	[238,198]	-3	hSpCas9	negative selection	1028746
102894822	102894845	12	+	26627737	GBM cells	viability after 21 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.642113338410775	[185]	[152,161]	6	hSpCas9	negative selection	1028747
102917070	102917093	12	-	26627737	GBM cells	viability after 21 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	-0.32405591271721557	[170]	[80,67]	-3	hSpCas9	negative selection	1028748
102852864	102852887	12	+	26627737	RPE1	viability after 9 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	0.22343925774856976	[431]	[108,220]	1	hSpCas9	negative selection	1111058
102855310	102855333	12	-	26627737	RPE1	viability after 9 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-0.39860365993531544	[1853]	[500,361]	-3	hSpCas9	negative selection	1111059
102866629	102866652	12	+	26627737	RPE1	viability after 9 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	-0.054570540006596224	[1198]	[391,321]	0	hSpCas9	negative selection	1111060
102877446	102877469	12	+	26627737	RPE1	viability after 9 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	-0.5717414852700844	[1867]	[468,295]	-4	hSpCas9	negative selection	1111061
102894822	102894845	12	+	26627737	RPE1	viability after 9 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	2.595022417450176	[285]	[471,629]	9	hSpCas9	negative selection	1111062
102917070	102917093	12	-	26627737	RPE1	viability after 9 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.8968053790404535	[707]	[327,521]	6	hSpCas9	negative selection	1111063
102852864	102852887	12	+	26627737	RPE1	viability after 12 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	0.09475523023697685	[431]	[121,125]	0	hSpCas9	negative selection	1193373
102855310	102855333	12	-	26627737	RPE1	viability after 12 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-0.6951344392870422	[1853]	[312,301]	-5	hSpCas9	negative selection	1193374
102866629	102866652	12	+	26627737	RPE1	viability after 12 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.08453896091293811	[1198]	[377,302]	0	hSpCas9	negative selection	1193375
102877446	102877469	12	+	26627737	RPE1	viability after 12 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	-1.4388949025137325	[1867]	[188,180]	-7	hSpCas9	negative selection	1193376
102894822	102894845	12	+	26627737	RPE1	viability after 12 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	2.8930093834880957	[285]	[494,650]	9	hSpCas9	negative selection	1193377
102917070	102917093	12	-	26627737	RPE1	viability after 12 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.09140307689998228	[707]	[156,250]	0	hSpCas9	negative selection	1193378
102852864	102852887	12	+	26627737	RPE1	viability after 15 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	0.6367513376926752	[431]	[20,352]	4	hSpCas9	negative selection	1275688
102855310	102855333	12	-	26627737	RPE1	viability after 15 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-0.6725146350635982	[1853]	[494,168]	-4	hSpCas9	negative selection	1275689
102866629	102866652	12	+	26627737	RPE1	viability after 15 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.4457053368224788	[1198]	[661,268]	3	hSpCas9	negative selection	1275690
102877446	102877469	12	+	26627737	RPE1	viability after 15 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	-1.4175091433141798	[1867]	[179,214]	-7	hSpCas9	negative selection	1275691
102894822	102894845	12	+	26627737	RPE1	viability after 15 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	3.108904647324768	[285]	[586,804]	9	hSpCas9	negative selection	1275692
102917070	102917093	12	-	26627737	RPE1	viability after 15 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.8322952326958348	[707]	[322,388]	5	hSpCas9	negative selection	1275693
102852864	102852887	12	+	26627737	RPE1	viability after 18 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	-0.07296093060150943	[431]	[3,224]	0	hSpCas9	negative selection	1358003
102855310	102855333	12	-	26627737	RPE1	viability after 18 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-1.37490261655068	[1853]	[175,210]	-7	hSpCas9	negative selection	1358004
102866629	102866652	12	+	26627737	RPE1	viability after 18 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.2758548712412364	[1198]	[471,305]	1	hSpCas9	negative selection	1358005
102877446	102877469	12	+	26627737	RPE1	viability after 18 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	-0.7642585904588091	[1867]	[86,520]	-5	hSpCas9	negative selection	1358006
102894822	102894845	12	+	26627737	RPE1	viability after 18 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	2.9072873136365667	[285]	[506,655]	9	hSpCas9	negative selection	1358007
102917070	102917093	12	-	26627737	RPE1	viability after 18 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.671631169688597	[707]	[226,386]	4	hSpCas9	negative selection	1358008
102852864	102852887	12	+	26627737	HeLa	viability after 8 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	4.690848027255011	[12]	[133,234,71]	9	hSpCas9	negative selection	1440318
102855310	102855333	12	-	26627737	HeLa	viability after 8 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-0.28903157272257085	[960]	[285,528,208]	-3	hSpCas9	negative selection	1440319
102866629	102866652	12	+	26627737	HeLa	viability after 8 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	-0.20511788034644196	[388]	[129,162,143]	-2	hSpCas9	negative selection	1440320
102877446	102877469	12	+	26627737	HeLa	viability after 8 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	-0.19027877169297658	[1076]	[365,558,304]	-2	hSpCas9	negative selection	1440321
102894822	102894845	12	+	26627737	HeLa	viability after 8 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.3941643320365679	[375]	[250,231,172]	3	hSpCas9	negative selection	1440322
102917070	102917093	12	-	26627737	HeLa	viability after 8 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.08346214034113991	[274]	[229,133,44]	0	hSpCas9	negative selection	1440323
102852864	102852887	12	+	26627737	HeLa	viability after 12 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	3.943025894616786	[12]	[145,98,2]	9	hSpCas9	negative selection	1522633
102855310	102855333	12	-	26627737	HeLa	viability after 12 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-1.190798210776513	[960]	[172,172,175]	-8	hSpCas9	negative selection	1522634
102866629	102866652	12	+	26627737	HeLa	viability after 12 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.11587357285973778	[388]	[175,104,248]	1	hSpCas9	negative selection	1522635
102877446	102877469	12	+	26627737	HeLa	viability after 12 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	0.18530192738082407	[1076]	[638,478,406]	1	hSpCas9	negative selection	1522636
102894822	102894845	12	+	26627737	HeLa	viability after 12 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.21246785098911936	[375]	[220,116,209]	2	hSpCas9	negative selection	1522637
102917070	102917093	12	-	26627737	HeLa	viability after 12 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	-0.1566825601298667	[274]	[94,126,80]	-1	hSpCas9	negative selection	1522638
102852864	102852887	12	+	26627737	HeLa	viability after 15 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	4.845928968328306	[12]	[179,126,148]	9	hSpCas9	negative selection	1604948
102855310	102855333	12	-	26627737	HeLa	viability after 15 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-0.4060617595281203	[960]	[316,447,105]	-4	hSpCas9	negative selection	1604949
102866629	102866652	12	+	26627737	HeLa	viability after 15 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	-0.2073806320145099	[388]	[88,162,161]	-2	hSpCas9	negative selection	1604950
102877446	102877469	12	+	26627737	HeLa	viability after 15 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	-0.2723342809489413	[1076]	[247,425,420]	-2	hSpCas9	negative selection	1604951
102894822	102894845	12	+	26627737	HeLa	viability after 15 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.5626259862343925	[375]	[237,214,224]	4	hSpCas9	negative selection	1604952
102917070	102917093	12	-	26627737	HeLa	viability after 15 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.15542950356619223	[274]	[111,91,173]	1	hSpCas9	negative selection	1604953
102852864	102852887	12	+	26627737	HeLa	viability after 18 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	4.8198598579047465	[12]	[113,106,148]	9	hSpCas9	negative selection	1687263
102855310	102855333	12	-	26627737	HeLa	viability after 18 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-0.3729368987501811	[960]	[213,385,105]	-3	hSpCas9	negative selection	1687264
102866629	102866652	12	+	26627737	HeLa	viability after 18 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	-0.18107475479336663	[388]	[66,131,161]	-1	hSpCas9	negative selection	1687265
102877446	102877469	12	+	26627737	HeLa	viability after 18 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	-0.23799594604102126	[1076]	[175,361,420]	-2	hSpCas9	negative selection	1687266
102894822	102894845	12	+	26627737	HeLa	viability after 18 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.5596351770373903	[375]	[157,178,224]	4	hSpCas9	negative selection	1687267
102917070	102917093	12	-	26627737	HeLa	viability after 18 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.16674002896278867	[274]	[77,74,173]	1	hSpCas9	negative selection	1687268
102852864	102852887	12	+	26627737	HCT116	viability after 6 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	4.377451562055788	[17]	[101,34]	9	hSpCas9	negative selection	1769578
102855310	102855333	12	-	26627737	HCT116	viability after 6 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-0.6804622906440922	[1529]	[336,46]	-4	hSpCas9	negative selection	1769579
102866629	102866652	12	+	26627737	HCT116	viability after 6 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	1.5206855952246936	[522]	[650,6]	7	hSpCas9	negative selection	1769580
102877446	102877469	12	+	26627737	HCT116	viability after 6 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	0.6914419509958671	[1975]	[850,308]	4	hSpCas9	negative selection	1769581
102894822	102894845	12	+	26627737	HCT116	viability after 6 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	-0.1648652551418095	[653]	[92,90]	-1	hSpCas9	negative selection	1769582
102917070	102917093	12	-	26627737	HCT116	viability after 6 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	-0.0025779980058566743	[277]	[22,54]	0	hSpCas9	negative selection	1769583
102852864	102852887	12	+	26627737	HCT116	viability after 8 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	-0.5823623038906154	[91]	[59,4,36]	-6	hSpCas9	negative selection	1851893
102855310	102855333	12	-	26627737	HCT116	viability after 8 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	0.162112402161542	[595]	[347,381,371]	1	hSpCas9	negative selection	1851894
102866629	102866652	12	+	26627737	HCT116	viability after 8 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.5582357660147002	[235]	[153,163,254]	5	hSpCas9	negative selection	1851895
102877446	102877469	12	+	26627737	HCT116	viability after 8 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	1.1468413883292707	[309]	[357,285,488]	8	hSpCas9	negative selection	1851896
102894822	102894845	12	+	26627737	HCT116	viability after 8 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.7919954522239554	[261]	[242,356,150]	7	hSpCas9	negative selection	1851897
102917070	102917093	12	-	26627737	HCT116	viability after 8 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.2208521095393411	[156]	[101,141,58]	2	hSpCas9	negative selection	1851898
102852864	102852887	12	+	26627737	HCT116	viability after 9 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	3.497154998232978	[17]	[65,44]	9	hSpCas9	negative selection	1934208
102855310	102855333	12	-	26627737	HCT116	viability after 9 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	0.29517059205147467	[1529]	[612,412]	2	hSpCas9	negative selection	1934209
102866629	102866652	12	+	26627737	HCT116	viability after 9 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.15296048701105286	[522]	[104,194]	1	hSpCas9	negative selection	1934210
102877446	102877469	12	+	26627737	HCT116	viability after 9 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	-0.10366585707268938	[1975]	[399,562]	0	hSpCas9	negative selection	1934211
102894822	102894845	12	+	26627737	HCT116	viability after 9 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	-1.0412146964640518	[653]	[152,30]	-6	hSpCas9	negative selection	1934212
102917070	102917093	12	-	26627737	HCT116	viability after 9 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.4216933339739857	[277]	[204,15]	3	hSpCas9	negative selection	1934213
102852864	102852887	12	+	26627737	HCT116	viability after 12 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	-1.4108740407759972	[91]	[12,17,23]	-8	hSpCas9	negative selection	2016523
102855310	102855333	12	-	26627737	HCT116	viability after 12 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-0.04270398102745132	[595]	[359,331,215]	0	hSpCas9	negative selection	2016524
102866629	102866652	12	+	26627737	HCT116	viability after 12 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.7829915279177861	[235]	[261,173,198]	7	hSpCas9	negative selection	2016525
102877446	102877469	12	+	26627737	HCT116	viability after 12 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	1.6189651351065906	[309]	[673,337,469]	9	hSpCas9	negative selection	2016526
102894822	102894845	12	+	26627737	HCT116	viability after 12 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.6423782007262402	[261]	[204,312,129]	6	hSpCas9	negative selection	2016527
102917070	102917093	12	-	26627737	HCT116	viability after 12 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.3053233401721682	[156]	[115,75,111]	3	hSpCas9	negative selection	2016528
102852864	102852887	12	+	26627737	HCT116	viability after 15 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	-2.3900038213582784	[91]	[7,12,8]	-9	hSpCas9	negative selection	2098838
102855310	102855333	12	-	26627737	HCT116	viability after 15 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-0.048318890325520725	[595]	[537,380,101]	0	hSpCas9	negative selection	2098839
102866629	102866652	12	+	26627737	HCT116	viability after 15 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.957108624771994	[235]	[360,152,286]	7	hSpCas9	negative selection	2098840
102877446	102877469	12	+	26627737	HCT116	viability after 15 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	1.2745333258495852	[309]	[410,390,486]	8	hSpCas9	negative selection	2098841
102894822	102894845	12	+	26627737	HCT116	viability after 15 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.9312368220510595	[261]	[234,294,323]	7	hSpCas9	negative selection	2098842
102917070	102917093	12	-	26627737	HCT116	viability after 15 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.4132657613386128	[156]	[69,70,211]	4	hSpCas9	negative selection	2098843
102852864	102852887	12	+	26627737	HCT116	viability after 18 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	-1.5030715503911412	[91]	[35,7,2]	-8	hSpCas9	negative selection	2181153
102855310	102855333	12	-	26627737	HCT116	viability after 18 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	0.2224714905761539	[595]	[551,294,155]	2	hSpCas9	negative selection	2181154
102866629	102866652	12	+	26627737	HCT116	viability after 18 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	1.370505810856181	[235]	[356,243,286]	8	hSpCas9	negative selection	2181155
102877446	102877469	12	+	26627737	HCT116	viability after 18 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	1.624507098660627	[309]	[517,458,406]	9	hSpCas9	negative selection	2181156
102894822	102894845	12	+	26627737	HCT116	viability after 18 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.5462763759534898	[261]	[147,284,111]	4	hSpCas9	negative selection	2181157
102917070	102917093	12	-	26627737	HCT116	viability after 18 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	-0.3837247830480278	[156]	[52,21,103]	-4	hSpCas9	negative selection	2181158
102917773	102917796	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATAGCTGGAGAACACCAGGCTGG	PAH	ENSG00000171759	2.896399995667789	[355,98]	[663,51]	8	dCas9-VP64	positive selection	2383558
102917759	102917782	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATCTGGGTTTAAATCCAGCCTGG	PAH	ENSG00000171759	0.6607092698427669	[36,31]	[6,16]	3	dCas9-VP64	positive selection	2383559
102917742	102917765	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGCAAATGTAAGAGCGATCTGG	PAH	ENSG00000171759	3.7009811723744086	[20,64]	[8,250]	9	dCas9-VP64	positive selection	2383560
102892534	102892557	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCTATTGAAGGACATCTTGG	PAH	ENSG00000171759	-2.286095389827816	[564,359]	[14,25]	-9	dCas9-VP64	positive selection	2404203
102872774	102872797	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCGTCATGTTGGCCAAG	PAH	ENSG00000171759	-0.08437565892322141	[6,12]	[1,0]	0	dCas9-VP64	positive selection	2405599
102957546	102957569	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGAGGAGGGGGGGGAGTGGGGG	PAH	ENSG00000171759	-1.5766411758282985	[34,77]	[2,3]	-8	dCas9-VP64	positive selection	2435499
102957573	102957596	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCCGCTCGCTGCAGCAGCGGGG	PAH	ENSG00000171759	2.537448797606637	[30,3]	[36,5]	8	dCas9-VP64	positive selection	2435500
102957473	102957496	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGAGAAAGGAACGGGAGGGGG	PAH	ENSG00000171759	2.3396194775986254	[0,1]	[0,2]	7	dCas9-VP64	positive selection	2435501
102917773	102917796	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATAGCTGGAGAACACCAGGCTGG	PAH	ENSG00000171759	0.6776292952691514	[283,268]	[185,104]	5	dCas9-VP64	positive selection	2478813
102917759	102917782	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATCTGGGTTTAAATCCAGCCTGG	PAH	ENSG00000171759	-0.08098978316551131	[68,40]	[25,7]	0	dCas9-VP64	positive selection	2478814
102917742	102917765	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGCAAATGTAAGAGCGATCTGG	PAH	ENSG00000171759	-0.5910714893968558	[90,307]	[14,67]	-6	dCas9-VP64	positive selection	2478815
102892534	102892557	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCTATTGAAGGACATCTTGG	PAH	ENSG00000171759	-0.6700350890027276	[299,266]	[39,74]	-6	dCas9-VP64	positive selection	2499458
102872774	102872797	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCGTCATGTTGGCCAAG	PAH	ENSG00000171759	-0.9208015753873722	[12,58]	[1,8]	-8	dCas9-VP64	positive selection	2500854
102957546	102957569	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGAGGAGGGGGGGGAGTGGGGG	PAH	ENSG00000171759	-0.08072725892323318	[33,119]	[21,23]	0	dCas9-VP64	positive selection	2530754
102957573	102957596	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCCGCTCGCTGCAGCAGCGGGG	PAH	ENSG00000171759	0.32510505906719933	[10,56]	[7,17]	2	dCas9-VP64	positive selection	2530755
102957473	102957496	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGAGAAAGGAACGGGAGGGGG	PAH	ENSG00000171759	0.648832333258363	[57,48]	[36,17]	5	dCas9-VP64	positive selection	2530756
102917102	102917125	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTGCGGTCCTGGAAAACCCAGG	PAH	ENSG00000171759	0.3530097926108704	[4,4]	[4,5]	7	hSpCas9	positive selection	3009442
102855299	102855322	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	-0.5700424985496009	[3,3]	[3,0]	-7	hSpCas9	positive selection	3009443
102894823	102894846	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.2114913587504064	[3,3]	[2,3]	4	hSpCas9	positive selection	3009444
102877482	102877505	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	-0.7727134413914141	[4,4]	[3,0]	-8	hSpCas9	positive selection	3009445
102917102	102917125	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTGCGGTCCTGGAAAACCCAGG	PAH	ENSG00000171759	-0.004358212031331465	[4,4]	[5,1]	0	hSpCas9	positive selection	3077300
102855299	102855322	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.3844382536288872	[3,3]	[3,3]	6	hSpCas9	positive selection	3077301
102894823	102894846	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.612379367316345	[3,3]	[2,4]	8	hSpCas9	positive selection	3077302
102877482	102877505	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	-0.0033680512133856255	[4,4]	[4,2]	0	hSpCas9	positive selection	3077303
102894823	102894846		+	24336571	A375	resistance to PLX after 7 days	CAGGCTACGTTTATCCAAATGGG	PAH	ENSG00000171759	0.5054173760882208	[14,17]	[20,24]	9	hSpCas9	positive selection	3133782
102912791	102912814		+	24336571	A375	resistance to PLX after 7 days	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	-0.18456565731833718	[6,7]	[4,6]	-6	hSpCas9	positive selection	3133783
102894747	102894770		+	24336571	A375	resistance to PLX after 7 days	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	-0.07200058346796853	[13,15]	[15,11]	-2	hSpCas9	positive selection	3133784
102894823	102894846		+	24336571	A375	resistance to PLX after 14 days	CAGGCTACGTTTATCCAAATGGG	PAH	ENSG00000171759	0.8850233667009123	[13,20]	[17,12]	7	hSpCas9	positive selection	3191575
102912791	102912814		+	24336571	A375	resistance to PLX after 14 days	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	-0.8905406756032173	[12,5]	[1,1]	-9	hSpCas9	positive selection	3191576
102894747	102894770		+	24336571	A375	resistance to PLX after 14 days	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	-0.07091430042858257	[11,16]	[5,6]	0	hSpCas9	positive selection	3191577
102894823	102894846		+	24336571	A375	viability after 7 days	CAGGCTACGTTTATCCAAATGGG	PAH	ENSG00000171759	0.15943004875430394	[14]	[14,17]	2	hSpCas9	negative selection	3249368
102912791	102912814		+	24336571	A375	viability after 7 days	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	-0.7462797730185387	[12]	[6,7]	-8	hSpCas9	negative selection	3249369
102894747	102894770		+	24336571	A375	viability after 7 days	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	-0.023697049050922236	[15]	[13,15]	0	hSpCas9	negative selection	3249370
102894823	102894846		+	24336571	A375	viability after 14 days	CAGGCTACGTTTATCCAAATGGG	PAH	ENSG00000171759	0.2900683017263442	[14]	[13,20]	4	hSpCas9	negative selection	3307161
102912791	102912814		+	24336571	A375	viability after 14 days	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	-0.3565592097710532	[12]	[12,5]	-4	hSpCas9	negative selection	3307162
102894747	102894770		+	24336571	A375	viability after 14 days	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	-0.05630066220781671	[15]	[11,16]	0	hSpCas9	negative selection	3307163
102894860	102894883	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	2.2129320920873816	[32,32]	[0,0]	7	hSpCas9	positive selection	3384496
102877486	102877509	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.20204377594464537	[132,132]	[0,0]	1	hSpCas9	positive selection	3384497
102894747	102894770	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.7735104341815785	[178,178]	[1,1]	4	hSpCas9	positive selection	3384498
102917102	102917125	12	-	26780180	HT29	viability (Avana library 4 designs)	ACTGCGGTCCTGGAAAACCCAGG	PAH	ENSG00000171759	0.533964042749658	[]	[]	2	hSpCas9	negative selection	3447477
102855298	102855321	12	+	26780180	HT29	viability (Avana library 4 designs)	CCTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.857293362332971	[]	[]	3	hSpCas9	negative selection	3447478
102894822	102894845	12	+	26780180	HT29	viability (Avana library 4 designs)	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	1.16003628375693	[]	[]	4	hSpCas9	negative selection	3447479
102877482	102877505	12	-	26780180	HT29	viability (Avana library 4 designs)	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	0.439978172795842	[]	[]	1	hSpCas9	negative selection	3447480
102855298	102855321	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.341794775587096	[]	[]	0	hSpCas9	negative selection	3541303
102877482	102877505	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	-1.86789200251072	[]	[]	-2	hSpCas9	negative selection	3541304
102917102	102917125	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGCGGTCCTGGAAAACCCAGG	PAH	ENSG00000171759	1.82882903046394	[]	[]	2	hSpCas9	negative selection	3541305
102894822	102894845	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	1.68696230627568	[]	[]	2	hSpCas9	negative selection	3541306
102855189	102855212	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCACTTCTTGAAAAGTACTGTGG	PAH	ENSG00000171759	-0.0734534446833435	[]	[]	0	hSpCas9	negative selection	3541307
102866631	102866654	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATCCTGTGTACCGTGCAAGACGG	PAH	ENSG00000171759	0.734258117265872	[]	[]	1	hSpCas9	negative selection	3541308
102855298	102855321	12	+	26780180	A375	viability (Avana lentiGuide)	CCTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	-1.91010899468712	[]	[]	-3	hSpCas9	negative selection	3649962
102877482	102877505	12	-	26780180	A375	viability (Avana lentiGuide)	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	-0.357867175432764	[]	[]	0	hSpCas9	negative selection	3649963
102917102	102917125	12	-	26780180	A375	viability (Avana lentiGuide)	ACTGCGGTCCTGGAAAACCCAGG	PAH	ENSG00000171759	6.19726481462263	[]	[]	5	hSpCas9	negative selection	3649964
102894822	102894845	12	+	26780180	A375	viability (Avana lentiGuide)	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	2.67157646159002	[]	[]	3	hSpCas9	negative selection	3649965
102855189	102855212	12	-	26780180	A375	viability (Avana lentiGuide)	CCACTTCTTGAAAAGTACTGTGG	PAH	ENSG00000171759	0.456111512114008	[]	[]	0	hSpCas9	negative selection	3649966
102866631	102866654	12	-	26780180	A375	viability (Avana lentiGuide)	ATCCTGTGTACCGTGCAAGACGG	PAH	ENSG00000171759	0.500562729473584	[]	[]	0	hSpCas9	negative selection	3649967
102855298	102855321	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	-0.11361177099537036	[5]	[4,4]	-2	hSpCas9	positive selection	3758621
102877482	102877505	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	-0.1353784705724952	[5]	[5,3]	-2	hSpCas9	positive selection	3758622
102917102	102917125	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGCGGTCCTGGAAAACCCAGG	PAH	ENSG00000171759	0.08020768713968474	[5]	[5,5]	2	hSpCas9	positive selection	3758623
102894822	102894845	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	-0.016098415412056942	[4]	[4,4]	0	hSpCas9	positive selection	3758624
102855189	102855212	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACTTCTTGAAAAGTACTGTGG	PAH	ENSG00000171759	-0.18694625018713124	[5]	[5,3]	-3	hSpCas9	positive selection	3758625
102866631	102866654	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCCTGTGTACCGTGCAAGACGG	PAH	ENSG00000171759	0.011366043817194416	[6]	[6,6]	0	hSpCas9	positive selection	3758626
102855298	102855321	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.13411024524978157	[5]	[4,4]	3	hSpCas9	positive selection	3867228
102877482	102877505	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	-0.1347822757494337	[5]	[4,3]	-2	hSpCas9	positive selection	3867229
102917102	102917125	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGCGGTCCTGGAAAACCCAGG	PAH	ENSG00000171759	0.09729577494963954	[6]	[6,6]	2	hSpCas9	positive selection	3867230
102894822	102894845	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.3686552670247675	[4]	[5,5]	9	hSpCas9	positive selection	3867231
102855189	102855212	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACTTCTTGAAAAGTACTGTGG	PAH	ENSG00000171759	0.3351872771822445	[4]	[4,5]	8	hSpCas9	positive selection	3867232
102866631	102866654	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCCTGTGTACCGTGCAAGACGG	PAH	ENSG00000171759	0.13527609578619904	[6]	[6,6]	3	hSpCas9	positive selection	3867233
102912790	102912813	12	-	26780180	A375	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.200381311058284	[]	[]	0	hSpCas9	negative selection	3978127
102912791	102912814	12	+	26780180	A375	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.132919890406475	[]	[]	0	hSpCas9	negative selection	3978128
102877487	102877510	12	-	26780180	A375	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.419573228963572	[]	[]	1	hSpCas9	negative selection	3978129
102894860	102894883	12	+	26780180	A375	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.232271403168809	[]	[]	0	hSpCas9	negative selection	3978130
102877486	102877509	12	+	26780180	A375	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.758594375326076	[]	[]	3	hSpCas9	negative selection	3978131
102894747	102894770	12	+	26780180	A375	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.605394840591117	[]	[]	2	hSpCas9	negative selection	3978132
102912790	102912813	12	-	26780180	HT29	viability (GeCKOv2 library)	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	1.11682105528256	[]	[]	5	hSpCas9	negative selection	4086093
102912791	102912814	12	+	26780180	HT29	viability (GeCKOv2 library)	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.316701361463044	[]	[]	0	hSpCas9	negative selection	4086094
102877487	102877510	12	-	26780180	HT29	viability (GeCKOv2 library)	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.8080679484835	[]	[]	3	hSpCas9	negative selection	4086095
102894860	102894883	12	+	26780180	HT29	viability (GeCKOv2 library)	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.527840648532019	[]	[]	1	hSpCas9	negative selection	4086096
102877486	102877509	12	+	26780180	HT29	viability (GeCKOv2 library)	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.649694908526853	[]	[]	2	hSpCas9	negative selection	4086097
102894747	102894770	12	+	26780180	HT29	viability (GeCKOv2 library)	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.712524196527312	[]	[]	2	hSpCas9	negative selection	4086098
102894823	102894846	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGGCTACGTTTATCCAAATGGG	PAH	ENSG00000171759	0.5822955971779086	[4]	[5,3]	9	hSpCas9	positive selection	4158628
102912791	102912814	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	-0.34549521311066467	[2]	[0,0]	-7	hSpCas9	positive selection	4158629
102894747	102894770	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	-0.1835964133814741	[4]	[1,2]	-4	hSpCas9	positive selection	4158630
102894823	102894846	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGGCTACGTTTATCCAAATGGG	PAH	ENSG00000171759	1.1273266297147315	[4]	[4,1,2,4]	8	hSpCas9	positive selection	4222650
102912791	102912814	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.004831039647368154	[3]	[0,2,2,0]	0	hSpCas9	positive selection	4222651
102894747	102894770	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	-0.0699604689315618	[4]	[3,4,0,0]	-1	hSpCas9	positive selection	4222652
102912791	102912814	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.3683495092894456	[4]	[4,3]	7	hSpCas9	positive selection	4288671
102912790	102912813	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.5896164739896916	[2]	[2,2]	9	hSpCas9	positive selection	4288672
102877487	102877510	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	-0.10377196588058771	[2]	[3,0]	-2	hSpCas9	positive selection	4288673
102894860	102894883	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.4489221526124293	[0]	[2,0]	8	hSpCas9	positive selection	4352924
102877486	102877509	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.18791000180942224	[2]	[2,1]	4	hSpCas9	positive selection	4352925
102894747	102894770	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.28112110463575035	[3]	[3,2]	5	hSpCas9	positive selection	4352926
102894748	102894770	12	+	27760321	OCIAML3	viability	CTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.6740086282837507	[254,226]	[255,357]	7	hSpCas9	negative selection	4425365
102894779	102894801	12	-	27760321	OCIAML3	viability	AGATCTTGAGGCATGACATTGG	PAH	ENSG00000171759	0.9645814004234754	[371,297]	[526,483]	9	hSpCas9	negative selection	4425366
102855221	102855243	12	+	27760321	OCIAML3	viability	ATTGTACTCATAGCAAGCATGG	PAH	ENSG00000171759	0.8037779875068913	[178,147]	[193,258]	8	hSpCas9	negative selection	4425367
102855299	102855321	12	+	27760321	OCIAML3	viability	CTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.2906019597338871	[413,340]	[279,462]	3	hSpCas9	negative selection	4425368
102866630	102866652	12	+	27760321	OCIAML3	viability	TCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	-1.1541725731302748	[4,0]	[0,0]	-7	hSpCas9	negative selection	4425369
102894748	102894770	12	+	27760321	OCIAML2	viability	CTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.6881270294956052	[254,226]	[301,328]	8	hSpCas9	negative selection	4508828
102894779	102894801	12	-	27760321	OCIAML2	viability	AGATCTTGAGGCATGACATTGG	PAH	ENSG00000171759	0.545655021306985	[371,297]	[350,448]	7	hSpCas9	negative selection	4508829
102855221	102855243	12	+	27760321	OCIAML2	viability	ATTGTACTCATAGCAAGCATGG	PAH	ENSG00000171759	0.38042090597541445	[178,147]	[154,192]	5	hSpCas9	negative selection	4508830
102855299	102855321	12	+	27760321	OCIAML2	viability	CTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.20616109252162787	[413,340]	[275,448]	2	hSpCas9	negative selection	4508831
102866630	102866652	12	+	27760321	OCIAML2	viability	TCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	-1.2029179383953235	[4,0]	[0,0]	-8	hSpCas9	negative selection	4508832
102894748	102894770	12	+	27760321	MV411	viability	CTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.2836811045069265	[254,226]	[80,361]	2	hSpCas9	negative selection	4592291
102894779	102894801	12	-	27760321	MV411	viability	AGATCTTGAGGCATGACATTGG	PAH	ENSG00000171759	1.2225254297650443	[371,297]	[376,716]	8	hSpCas9	negative selection	4592292
102855221	102855243	12	+	27760321	MV411	viability	ATTGTACTCATAGCAAGCATGG	PAH	ENSG00000171759	0.7747108173661952	[178,147]	[134,256]	6	hSpCas9	negative selection	4592293
102855299	102855321	12	+	27760321	MV411	viability	CTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	-0.023090549358752765	[413,340]	[263,213]	0	hSpCas9	negative selection	4592294
102866630	102866652	12	+	27760321	MV411	viability	TCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	-0.9090940042155928	[4,0]	[0,0]	-6	hSpCas9	negative selection	4592295
102894748	102894770	12	+	27760321	HL60	viability	CTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.4906362498007869	[254,226]	[315,233]	6	hSpCas9	negative selection	4675754
102894779	102894801	12	-	27760321	HL60	viability	AGATCTTGAGGCATGACATTGG	PAH	ENSG00000171759	0.5814131472810122	[371,297]	[509,297]	7	hSpCas9	negative selection	4675755
102855221	102855243	12	+	27760321	HL60	viability	ATTGTACTCATAGCAAGCATGG	PAH	ENSG00000171759	0.04152213553435358	[178,147]	[114,159]	0	hSpCas9	negative selection	4675756
102855299	102855321	12	+	27760321	HL60	viability	CTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.5489502970227642	[413,340]	[367,534]	6	hSpCas9	negative selection	4675757
102866630	102866652	12	+	27760321	HL60	viability	TCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	-1.2169641660097295	[4,0]	[0,0]	-8	hSpCas9	negative selection	4675758
102894748	102894770	12	+	27760321	HT1080	viability	CTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.8963612063266821	[226,176]	[123,177]	5	hSpCas9	negative selection	4759217
102894779	102894801	12	-	27760321	HT1080	viability	AGATCTTGAGGCATGACATTGG	PAH	ENSG00000171759	-6.724912829719318	[297,232]	[0,0]	-9	hSpCas9	negative selection	4759218
102855221	102855243	12	+	27760321	HT1080	viability	ATTGTACTCATAGCAAGCATGG	PAH	ENSG00000171759	1.508205050837611	[147,115]	[109,192]	8	hSpCas9	negative selection	4759219
102855299	102855321	12	+	27760321	HT1080	viability	CTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	1.2870522186091828	[340,265]	[221,374]	7	hSpCas9	negative selection	4759220
102866630	102866652	12	+	27760321	HT1080	viability	TCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	7.618479033687256	[0,0]	[89,67]	9	hSpCas9	negative selection	4759221
102894748	102894770	12	+	27760321	HT29	viability after 7 days	CTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.09215319601690619	[226,176]	[125,291,386]	1	hSpCas9	negative selection	4842680
102894779	102894801	12	-	27760321	HT29	viability after 7 days	AGATCTTGAGGCATGACATTGG	PAH	ENSG00000171759	-0.04030544812636688	[297,232]	[550,279,199]	0	hSpCas9	negative selection	4842681
102855221	102855243	12	+	27760321	HT29	viability after 7 days	ATTGTACTCATAGCAAGCATGG	PAH	ENSG00000171759	-0.1273145233783577	[147,115]	[179,116,171]	-2	hSpCas9	negative selection	4842682
102855299	102855321	12	+	27760321	HT29	viability after 7 days	CTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.3690203114557065	[340,265]	[739,499,310]	5	hSpCas9	negative selection	4842683
102866630	102866652	12	+	27760321	HT29	viability after 7 days	TCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	3.1620602857257287	[0,0]	[36,0,0]	9	hSpCas9	negative selection	4842684
102894748	102894770	12	+	27760321	HT29	viability after 25 days	CTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.622209291043157	[226,176]	[150,444,496]	7	hSpCas9	negative selection	4926143
102894779	102894801	12	-	27760321	HT29	viability after 25 days	AGATCTTGAGGCATGACATTGG	PAH	ENSG00000171759	0.04657094790501359	[297,232]	[384,169,387]	0	hSpCas9	negative selection	4926144
102855221	102855243	12	+	27760321	HT29	viability after 25 days	ATTGTACTCATAGCAAGCATGG	PAH	ENSG00000171759	0.798332350149003	[147,115]	[310,130,350]	8	hSpCas9	negative selection	4926145
102855299	102855321	12	+	27760321	HT29	viability after 25 days	CTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.5242221208044926	[340,265]	[432,505,567]	6	hSpCas9	negative selection	4926146
102866630	102866652	12	+	27760321	HT29	viability after 25 days	TCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.16757210297100933	[0,0]	[0,0,1]	1	hSpCas9	negative selection	4926147
102894748	102894770	12	+	27760321	HT29	viability after 22 days	CTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.3724835461520751	[226,176]	[138,499,271]	4	hSpCas9	negative selection	5009606
102894779	102894801	12	-	27760321	HT29	viability after 22 days	AGATCTTGAGGCATGACATTGG	PAH	ENSG00000171759	-0.1658158031513393	[297,232]	[225,341,253]	-2	hSpCas9	negative selection	5009607
102855221	102855243	12	+	27760321	HT29	viability after 22 days	ATTGTACTCATAGCAAGCATGG	PAH	ENSG00000171759	0.6887304233112989	[147,115]	[350,59,324]	7	hSpCas9	negative selection	5009608
102855299	102855321	12	+	27760321	HT29	viability after 22 days	CTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.7026381681878515	[340,265]	[431,685,598]	7	hSpCas9	negative selection	5009609
102866630	102866652	12	+	27760321	HT29	viability after 22 days	TCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	2.8080426075768434	[0,0]	[0,0,22]	9	hSpCas9	negative selection	5009610
102894748	102894770	12	+	27760321	HT29	viability after 19 days	CTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.27895276516761514	[226,176]	[458,243,160]	2	hSpCas9	negative selection	5093069
102894779	102894801	12	-	27760321	HT29	viability after 19 days	AGATCTTGAGGCATGACATTGG	PAH	ENSG00000171759	0.3120756749821423	[297,232]	[477,356,308]	3	hSpCas9	negative selection	5093070
102855221	102855243	12	+	27760321	HT29	viability after 19 days	ATTGTACTCATAGCAAGCATGG	PAH	ENSG00000171759	0.21088665531881357	[147,115]	[105,262,148]	2	hSpCas9	negative selection	5093071
102855299	102855321	12	+	27760321	HT29	viability after 19 days	CTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.3151784796149448	[340,265]	[674,382,268]	3	hSpCas9	negative selection	5093072
102866630	102866652	12	+	27760321	HT29	viability after 19 days	TCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	2.1763407452385337	[0,0]	[0,0,12]	9	hSpCas9	negative selection	5093073
102894748	102894770	12	+	27760321	HT29	viability after 16 days	CTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.6618594612882813	[226,176]	[267,475,316]	7	hSpCas9	negative selection	5176532
102894779	102894801	12	-	27760321	HT29	viability after 16 days	AGATCTTGAGGCATGACATTGG	PAH	ENSG00000171759	0.4117488672137139	[297,232]	[396,268,522]	4	hSpCas9	negative selection	5176533
102855221	102855243	12	+	27760321	HT29	viability after 16 days	ATTGTACTCATAGCAAGCATGG	PAH	ENSG00000171759	0.1820612408107709	[147,115]	[357,118,44]	2	hSpCas9	negative selection	5176534
102855299	102855321	12	+	27760321	HT29	viability after 16 days	CTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.636700316645434	[340,265]	[750,402,453]	7	hSpCas9	negative selection	5176535
102866630	102866652	12	+	27760321	HT29	viability after 16 days	TCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.832654485111326	[0,0]	[0,0,3]	8	hSpCas9	negative selection	5176536
102894748	102894770	12	+	27760321	HT29	viability after 13 days	CTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.6225449757004025	[226,176]	[184,610,290]	7	hSpCas9	negative selection	5259995
102894779	102894801	12	-	27760321	HT29	viability after 13 days	AGATCTTGAGGCATGACATTGG	PAH	ENSG00000171759	-0.062824620773551	[297,232]	[195,275,405]	0	hSpCas9	negative selection	5259996
102855221	102855243	12	+	27760321	HT29	viability after 13 days	ATTGTACTCATAGCAAGCATGG	PAH	ENSG00000171759	-0.022364826371171764	[147,115]	[171,54,220]	0	hSpCas9	negative selection	5259997
102855299	102855321	12	+	27760321	HT29	viability after 13 days	CTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.34951350076505816	[340,265]	[492,495,361]	4	hSpCas9	negative selection	5259998
102866630	102866652	12	+	27760321	HT29	viability after 13 days	TCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.17188215484912384	[0,0]	[1,0,0]	2	hSpCas9	negative selection	5259999
102894748	102894770	12	+	27760321	HT29	viability after 10 days	CTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.19680192659869944	[226,176]	[149,328,386]	2	hSpCas9	negative selection	5343458
102894779	102894801	12	-	27760321	HT29	viability after 10 days	AGATCTTGAGGCATGACATTGG	PAH	ENSG00000171759	-0.05499346071655187	[297,232]	[267,194,486]	0	hSpCas9	negative selection	5343459
102855221	102855243	12	+	27760321	HT29	viability after 10 days	ATTGTACTCATAGCAAGCATGG	PAH	ENSG00000171759	-0.1395340300572454	[147,115]	[193,130,123]	-2	hSpCas9	negative selection	5343460
102855299	102855321	12	+	27760321	HT29	viability after 10 days	CTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.31463457507714	[340,265]	[407,444,557]	4	hSpCas9	negative selection	5343461
102866630	102866652	12	+	27760321	HT29	viability after 10 days	TCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	2.962206036932378	[0,0]	[0,0,26]	9	hSpCas9	negative selection	5343462
102894748	102894770	12	+	27760321	MOLM13	viability	CTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	1.4710336550247982	[254,226]	[646,145]	8	hSpCas9	negative selection	5426921
102894779	102894801	12	-	27760321	MOLM13	viability	AGATCTTGAGGCATGACATTGG	PAH	ENSG00000171759	1.3850203538217494	[371,297]	[486,493]	8	hSpCas9	negative selection	5426922
102855221	102855243	12	+	27760321	MOLM13	viability	ATTGTACTCATAGCAAGCATGG	PAH	ENSG00000171759	0.4115383413979634	[178,147]	[173,77]	3	hSpCas9	negative selection	5426923
102855299	102855321	12	+	27760321	MOLM13	viability	CTCCATGTATTCCACTCGAGGG	PAH	ENSG00000171759	0.7233088778996171	[413,340]	[376,326]	5	hSpCas9	negative selection	5426924
102866630	102866652	12	+	27760321	MOLM13	viability	TCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	-0.6830371913879976	[4,0]	[0,0]	-4	hSpCas9	negative selection	5426925
102917231	102917254	12	+	27661255	K562	viability	GAGGAGAAGAGAGTTACAAAGGG	PAH	ENSG00000171759	0.10560126034674533	[957,1202]	[980,876]	3	dCas9-KRAB	negative selection	5499970
102917118	102917141	12	-	27661255	K562	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	-0.1505296891352801	[825,953]	[701,584]	-5	dCas9-KRAB	negative selection	5499971
102912791	102912814	12	+	27260156	BXPC3	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.2069920971738881	[1001]	[1158,867,1402,1458]	4	hSpCas9	negative selection	5561131
102912790	102912813	12	-	27260156	BXPC3	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.11653404754200647	[228]	[248,226,241,329]	2	hSpCas9	negative selection	5561132
102877487	102877510	12	-	27260156	BXPC3	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.4035809632279868	[381]	[527,564,382,642]	8	hSpCas9	negative selection	5561133
102894860	102894883	12	+	27260156	BXPC3	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.5429617289953348	[55]	[59,64,122,98]	9	hSpCas9	negative selection	5625384
102877486	102877509	12	+	27260156	BXPC3	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.06540782933627864	[261]	[353,148,320,326]	1	hSpCas9	negative selection	5625385
102894747	102894770	12	+	27260156	BXPC3	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.19333170334104993	[588]	[676,568,724,872]	4	hSpCas9	negative selection	5625386
102912791	102912814	12	+	27260156	A673	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.0238716675481061	[1001]	[1279,1070,1266,1285]	0	hSpCas9	negative selection	5682382
102912790	102912813	12	-	27260156	A673	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.3820301358685816	[228]	[320,310,493,298]	8	hSpCas9	negative selection	5682383
102877487	102877510	12	-	27260156	A673	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.0762265634875719	[381]	[445,562,453,462]	1	hSpCas9	negative selection	5682384
102894860	102894883	12	+	27260156	A673	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.3171280125945417	[55]	[108,44,110,72]	7	hSpCas9	negative selection	5746635
102877486	102877509	12	+	27260156	A673	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.22165739283026742	[261]	[425,406,305,331]	5	hSpCas9	negative selection	5746636
102894747	102894770	12	+	27260156	A673	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.1830605969649582	[588]	[754,703,838,914]	4	hSpCas9	negative selection	5746637
102912791	102912814	12	+	27260156	A375	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.5841317352360733	[1001]	[1591,2342,1515,1652]	8	hSpCas9	negative selection	5803633
102912790	102912813	12	-	27260156	A375	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.6100036165837187	[228]	[568,323,376,356]	8	hSpCas9	negative selection	5803634
102877487	102877510	12	-	27260156	A375	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.08146562831342191	[381]	[423,420,468,554]	1	hSpCas9	negative selection	5803635
102894860	102894883	12	+	27260156	A375	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	-0.5428912167968662	[55]	[30,64,67,20]	-6	hSpCas9	negative selection	5867886
102877486	102877509	12	+	27260156	A375	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.36114438677906086	[261]	[461,326,462,318]	5	hSpCas9	negative selection	5867887
102894747	102894770	12	+	27260156	A375	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.7078317643592666	[588]	[1104,1149,1412,857]	9	hSpCas9	negative selection	5867888
102912791	102912814	12	+	27260156	COLO741	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.028271129054174393	[1001]	[1534,1414,1005]	0	hSpCas9	negative selection	5924884
102912790	102912813	12	-	27260156	COLO741	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	-0.0764955570424446	[228]	[394,244,206]	-2	hSpCas9	negative selection	5924885
102877487	102877510	12	-	27260156	COLO741	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.3640558534951258	[381]	[585,739,558]	7	hSpCas9	negative selection	5924886
102894860	102894883	12	+	27260156	COLO741	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	-0.3085279453055838	[55]	[51,38,79]	-6	hSpCas9	negative selection	5989137
102877486	102877509	12	+	27260156	COLO741	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	-0.16456231849601033	[261]	[226,343,316]	-4	hSpCas9	negative selection	5989138
102894747	102894770	12	+	27260156	COLO741	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.19695569349386982	[588]	[730,1104,747]	4	hSpCas9	negative selection	5989139
102912791	102912814	12	+	27260156	CAL120	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	-0.09268156261591609	[1001]	[1699,983,907]	-1	hSpCas9	negative selection	6046135
102912790	102912813	12	-	27260156	CAL120	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.2268792688272211	[228]	[440,212,361]	3	hSpCas9	negative selection	6046136
102877487	102877510	12	-	27260156	CAL120	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	-0.327471271713205	[381]	[461,428,259]	-5	hSpCas9	negative selection	6046137
102894860	102894883	12	+	27260156	CAL120	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	1.2894915100246742	[55]	[249,161,111]	9	hSpCas9	negative selection	6110388
102877486	102877509	12	+	27260156	CAL120	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.20270046306928158	[261]	[426,315,389]	3	hSpCas9	negative selection	6110389
102894747	102894770	12	+	27260156	CAL120	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.45804175179573486	[588]	[1028,1076,918]	7	hSpCas9	negative selection	6110390
102912791	102912814	12	+	27260156	CADOES1	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.3007378817223083	[1001]	[1004,1164,968,1464]	5	hSpCas9	negative selection	6167386
102912790	102912813	12	-	27260156	CADOES1	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.36488835079428206	[228]	[218,315,219,344]	6	hSpCas9	negative selection	6167387
102877487	102877510	12	-	27260156	CADOES1	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	-0.010536332753531719	[381]	[322,384,322,380]	0	hSpCas9	negative selection	6167388
102894860	102894883	12	+	27260156	CADOES1	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.8921183634725502	[55]	[92,118,95,77]	9	hSpCas9	negative selection	6231639
102877486	102877509	12	+	27260156	CADOES1	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	-0.14480431699287089	[261]	[215,198,209,257]	-3	hSpCas9	negative selection	6231640
102894747	102894770	12	+	27260156	CADOES1	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.34982483407252024	[588]	[532,657,719,888]	6	hSpCas9	negative selection	6231641
102912791	102912814	12	+	27260156	EWS502	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.2079252619290528	[1001]	[1161,1075,1154,1540]	3	hSpCas9	negative selection	6288637
102912790	102912813	12	-	27260156	EWS502	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.511659763777319	[228]	[322,259,279,537]	8	hSpCas9	negative selection	6288638
102877487	102877510	12	-	27260156	EWS502	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.21333126931999596	[381]	[454,381,530,515]	4	hSpCas9	negative selection	6288639
102894860	102894883	12	+	27260156	EWS502	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	1.3441940152686542	[55]	[229,167,55,134]	9	hSpCas9	negative selection	6352890
102877486	102877509	12	+	27260156	EWS502	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.25186124567003	[261]	[341,297,424,250]	4	hSpCas9	negative selection	6352891
102894747	102894770	12	+	27260156	EWS502	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.3691706734248938	[588]	[744,806,937,733]	6	hSpCas9	negative selection	6352892
102912791	102912814	12	+	27260156	EW8	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.15160604806280165	[1001]	[985,698,909,1016]	3	hSpCas9	negative selection	6409888
102912790	102912813	12	-	27260156	EW8	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.4117534637831656	[228]	[210,279,252,237]	7	hSpCas9	negative selection	6409889
102877487	102877510	12	-	27260156	EW8	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.30746122770785994	[381]	[531,448,296,284]	5	hSpCas9	negative selection	6409890
102894860	102894883	12	+	27260156	EW8	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.4843260053965097	[55]	[51,99,61,38]	8	hSpCas9	negative selection	6474141
102877486	102877509	12	+	27260156	EW8	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.09191687706455987	[261]	[232,247,174,257]	1	hSpCas9	negative selection	6474142
102894747	102894770	12	+	27260156	EW8	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.3718268997560376	[588]	[614,681,515,672]	6	hSpCas9	negative selection	6474143
102912791	102912814	12	+	27260156	CORL105	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.1621440794138802	[1001]	[1314,1370,1237,1312]	3	hSpCas9	negative selection	6531139
102912790	102912813	12	-	27260156	CORL105	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.171361452243584	[228]	[202,294,421,302]	3	hSpCas9	negative selection	6531140
102877487	102877510	12	-	27260156	CORL105	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	-0.09915432799505469	[381]	[526,319,438,392]	-2	hSpCas9	negative selection	6531141
102894860	102894883	12	+	27260156	CORL105	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.05999236250644868	[55]	[108,50,60,52]	1	hSpCas9	negative selection	6595392
102877486	102877509	12	+	27260156	CORL105	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	-0.01292976230517584	[261]	[347,238,331,303]	0	hSpCas9	negative selection	6595393
102894747	102894770	12	+	27260156	CORL105	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.34638238151411954	[588]	[860,693,985,984]	6	hSpCas9	negative selection	6595394
102912791	102912814	12	+	27260156	HS294T	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.1616816278561597	[1001]	[363,434,499,440]	2	hSpCas9	negative selection	6652390
102912790	102912813	12	-	27260156	HS294T	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.5752402930131137	[228]	[78,148,100,216]	7	hSpCas9	negative selection	6652391
102877487	102877510	12	-	27260156	HS294T	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.0961298703360042	[381]	[197,111,148,171]	1	hSpCas9	negative selection	6652392
102894860	102894883	12	+	27260156	HS294T	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	-0.5520913028633823	[55]	[13,8,17,18]	-7	hSpCas9	negative selection	6716643
102877486	102877509	12	+	27260156	HS294T	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	-0.19724299623497998	[261]	[86,74,86,107]	-3	hSpCas9	negative selection	6716644
102894747	102894770	12	+	27260156	HS294T	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.4638270034863425	[588]	[267,404,267,315]	6	hSpCas9	negative selection	6716645
102912791	102912814	12	+	27260156	HCC44	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.12086130638755255	[1001]	[1686,970,1508,889]	2	hSpCas9	negative selection	6773641
102912790	102912813	12	-	27260156	HCC44	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.6392084001284437	[228]	[328,296,525,484]	9	hSpCas9	negative selection	6773642
102877487	102877510	12	-	27260156	HCC44	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	-0.6893984845809227	[381]	[193,249,400,243]	-7	hSpCas9	negative selection	6773643
102894860	102894883	12	+	27260156	HCC44	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.46489235246305016	[55]	[32,167,67,60]	7	hSpCas9	negative selection	6837894
102877486	102877509	12	+	27260156	HCC44	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.07512166950391996	[261]	[355,324,376,204]	1	hSpCas9	negative selection	6837895
102894747	102894770	12	+	27260156	HCC44	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.38038037484966986	[588]	[986,619,1081,855]	6	hSpCas9	negative selection	6837896
102912791	102912814	12	+	27260156	G402	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.25331735369159447	[1001]	[2223,1170,1304,1228]	3	hSpCas9	negative selection	6894892
102912790	102912813	12	-	27260156	G402	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.9107727248815454	[228]	[383,266,317,1067]	9	hSpCas9	negative selection	6894893
102877487	102877510	12	-	27260156	G402	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	-0.41430006225360694	[381]	[297,336,351,399]	-5	hSpCas9	negative selection	6894894
102894860	102894883	12	+	27260156	G402	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	1.267622692965574	[55]	[86,16,121,399]	9	hSpCas9	negative selection	6959145
102877486	102877509	12	+	27260156	G402	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	1.0095674621822834	[261]	[1004,213,518,850]	9	hSpCas9	negative selection	6959146
102894747	102894770	12	+	27260156	G402	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.7358070631550435	[588]	[1736,1181,1189,771]	8	hSpCas9	negative selection	6959147
102912791	102912814	12	+	27260156	L33	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	-0.031602337242843115	[1001]	[1017,342,534,1210]	0	hSpCas9	negative selection	7016143
102912790	102912813	12	-	27260156	L33	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.5427722740286582	[228]	[288,183,223,241]	9	hSpCas9	negative selection	7016144
102877487	102877510	12	-	27260156	L33	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.4585160901506965	[381]	[500,224,315,546]	8	hSpCas9	negative selection	7016145
102894860	102894883	12	+	27260156	L33	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	-0.13418880893208707	[55]	[61,14,35,47]	-3	hSpCas9	negative selection	7080396
102877486	102877509	12	+	27260156	L33	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	-0.13393151196964115	[261]	[230,77,152,289]	-3	hSpCas9	negative selection	7080397
102894747	102894770	12	+	27260156	L33	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.17384848660828872	[588]	[603,258,477,662]	4	hSpCas9	negative selection	7080398
102912791	102912814	12	+	27260156	K562	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.7483859094779266	[1001]	[1007,1473,1235,2133]	8	hSpCas9	negative selection	7137394
102912790	102912813	12	-	27260156	K562	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.41327624134878327	[228]	[307,397,103,279]	5	hSpCas9	negative selection	7137395
102877487	102877510	12	-	27260156	K562	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.17834968496048276	[381]	[612,287,237,404]	2	hSpCas9	negative selection	7137396
102894860	102894883	12	+	27260156	K562	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.8924451224926226	[55]	[148,111,55,60]	9	hSpCas9	negative selection	7201647
102877486	102877509	12	+	27260156	K562	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.2433130313814844	[261]	[161,280,308,331]	3	hSpCas9	negative selection	7201648
102894747	102894770	12	+	27260156	K562	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.45090165369482677	[588]	[715,1125,644,423]	6	hSpCas9	negative selection	7201649
102912791	102912814	12	+	27260156	HT29	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.11673677121660697	[1001]	[1292,1367,1498,1137]	2	hSpCas9	negative selection	7258645
102912790	102912813	12	-	27260156	HT29	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.5284112915205725	[228]	[416,591,320,302]	8	hSpCas9	negative selection	7258646
102877487	102877510	12	-	27260156	HT29	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.14803385446053738	[381]	[513,740,350,472]	3	hSpCas9	negative selection	7258647
102894860	102894883	12	+	27260156	HT29	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.16044017707361968	[55]	[149,90,22,49]	3	hSpCas9	negative selection	7322898
102877486	102877509	12	+	27260156	HT29	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	-0.060721428985390236	[261]	[350,205,349,306]	-1	hSpCas9	negative selection	7322899
102894747	102894770	12	+	27260156	HT29	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.4408897853334421	[588]	[1167,898,846,974]	8	hSpCas9	negative selection	7322900
102912791	102912814	12	+	27260156	MHHES1	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.3139773209006109	[1001]	[1665,1607,1237,1172]	6	hSpCas9	negative selection	7379896
102912790	102912813	12	-	27260156	MHHES1	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.48440773785483826	[228]	[508,365,406,207]	8	hSpCas9	negative selection	7379897
102877487	102877510	12	-	27260156	MHHES1	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	-0.08013268634778326	[381]	[490,337,362,424]	-1	hSpCas9	negative selection	7379898
102894860	102894883	12	+	27260156	MHHES1	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.5087975726388163	[55]	[110,158,36,64]	8	hSpCas9	negative selection	7444149
102877486	102877509	12	+	27260156	MHHES1	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.1608645380508812	[261]	[541,353,180,274]	3	hSpCas9	negative selection	7444150
102894747	102894770	12	+	27260156	MHHES1	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.343024727026126	[588]	[1206,870,770,600]	6	hSpCas9	negative selection	7444151
102912791	102912814	12	+	27260156	MEWO	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.06597765621557428	[1001]	[859,1017,1041]	1	hSpCas9	negative selection	7501147
102912790	102912813	12	-	27260156	MEWO	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.4885200320822233	[228]	[413,230,278]	8	hSpCas9	negative selection	7501148
102877487	102877510	12	-	27260156	MEWO	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	-0.04787394078889434	[381]	[376,374,290]	-1	hSpCas9	negative selection	7501149
102894860	102894883	12	+	27260156	MEWO	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.3281336690983978	[55]	[84,70,44]	7	hSpCas9	negative selection	7565400
102877486	102877509	12	+	27260156	MEWO	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	-0.0408879396809525	[261]	[235,301,175]	-1	hSpCas9	negative selection	7565401
102894747	102894770	12	+	27260156	MEWO	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	-0.029313175896124977	[588]	[873,433,376]	0	hSpCas9	negative selection	7565402
102912791	102912814	12	+	27260156	LNCAPCLONEFGC	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.4626865080698166	[1001]	[1224,1182,1374,1242]	7	hSpCas9	negative selection	7622398
102912790	102912813	12	-	27260156	LNCAPCLONEFGC	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.6982439009195605	[228]	[217,240,661,281]	9	hSpCas9	negative selection	7622399
102877487	102877510	12	-	27260156	LNCAPCLONEFGC	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.21607817011670713	[381]	[338,376,459,442]	3	hSpCas9	negative selection	7622400
102894860	102894883	12	+	27260156	LNCAPCLONEFGC	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.9091141016681732	[55]	[122,71,27,148]	9	hSpCas9	negative selection	7686651
102877486	102877509	12	+	27260156	LNCAPCLONEFGC	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.26122637634932544	[261]	[377,273,213,259]	4	hSpCas9	negative selection	7686652
102894747	102894770	12	+	27260156	LNCAPCLONEFGC	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.5281470900796961	[588]	[645,732,1072,674]	8	hSpCas9	negative selection	7686653
102912791	102912814	12	+	27260156	PANC0327	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.8818740582704909	[1001]	[1932,1371,1643,1669]	9	hSpCas9	negative selection	7743649
102912790	102912813	12	-	27260156	PANC0327	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.26801489884000973	[228]	[147,444,224,127]	4	hSpCas9	negative selection	7743650
102877487	102877510	12	-	27260156	PANC0327	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	-0.10968090689482807	[381]	[546,359,212,150]	-2	hSpCas9	negative selection	7743651
102894860	102894883	12	+	27260156	PANC0327	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.7269929517065381	[55]	[159,17,82,82]	9	hSpCas9	negative selection	7807902
102877486	102877509	12	+	27260156	PANC0327	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.06831593426990046	[261]	[235,215,264,261]	1	hSpCas9	negative selection	7807903
102894747	102894770	12	+	27260156	PANC0327	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.2991698925383662	[588]	[655,543,751,636]	4	hSpCas9	negative selection	7807904
102912791	102912814	12	+	27260156	NCIH2009	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.06008579533476266	[1001]	[1701,1399,1322]	0	hSpCas9	negative selection	7864900
102912790	102912813	12	-	27260156	NCIH2009	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.5508051351706911	[228]	[559,431,431]	7	hSpCas9	negative selection	7864901
102877487	102877510	12	-	27260156	NCIH2009	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.19517873437674704	[381]	[807,389,676]	2	hSpCas9	negative selection	7864902
102894860	102894883	12	+	27260156	NCIH2009	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.654282937951312	[55]	[214,87,84]	8	hSpCas9	negative selection	7929153
102877486	102877509	12	+	27260156	NCIH2009	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	-0.12703118724429618	[261]	[489,314,230]	-2	hSpCas9	negative selection	7929154
102894747	102894770	12	+	27260156	NCIH2009	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.5138583244564521	[588]	[1353,1089,1115]	7	hSpCas9	negative selection	7929155
102912791	102912814	12	+	27260156	NCIH1373	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.5932015507967878	[1001]	[1723,1709,1864,381]	6	hSpCas9	negative selection	7986151
102912790	102912813	12	-	27260156	NCIH1373	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	1.177155719182753	[228]	[412,770,443,170]	9	hSpCas9	negative selection	7986152
102877487	102877510	12	-	27260156	NCIH1373	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	-0.02621349237623044	[381]	[305,419,388,145]	0	hSpCas9	negative selection	7986153
102894860	102894883	12	+	27260156	NCIH1373	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	1.520579222760343	[55]	[71,88,434,27]	9	hSpCas9	negative selection	8050404
102877486	102877509	12	+	27260156	NCIH1373	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.6065221440654145	[261]	[383,519,604,63]	6	hSpCas9	negative selection	8050405
102894747	102894770	12	+	27260156	NCIH1373	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.799636326419537	[588]	[1044,1220,1297,259]	7	hSpCas9	negative selection	8050406
102912791	102912814	12	+	27260156	PATU8902	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.8954730224774221	[1001]	[2850,3045,2061,2532]	8	hSpCas9	negative selection	8107402
102912790	102912813	12	-	27260156	PATU8902	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.439641858166801	[228]	[344,290,541,532]	4	hSpCas9	negative selection	8107403
102877487	102877510	12	-	27260156	PATU8902	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	-0.1702430660499773	[381]	[574,251,464,611]	-2	hSpCas9	negative selection	8107404
102894860	102894883	12	+	27260156	PATU8902	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.7471101062603323	[55]	[81,15,276,106]	7	hSpCas9	negative selection	8171655
102877486	102877509	12	+	27260156	PATU8902	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.7821081852323405	[261]	[881,824,331,527]	8	hSpCas9	negative selection	8171656
102894747	102894770	12	+	27260156	PATU8902	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.6561380612164225	[588]	[1256,1819,873,1323]	7	hSpCas9	negative selection	8171657
102912791	102912814	12	+	27260156	PANC1	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.2367333412421162	[1001]	[1064,1393,817,862]	4	hSpCas9	negative selection	8228653
102912790	102912813	12	-	27260156	PANC1	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.43326319474301145	[228]	[278,243,309,226]	7	hSpCas9	negative selection	8228654
102877487	102877510	12	-	27260156	PANC1	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.3665800684673992	[381]	[291,620,416,401]	6	hSpCas9	negative selection	8228655
102894860	102894883	12	+	27260156	PANC1	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.925287337676207	[55]	[121,90,105,50]	9	hSpCas9	negative selection	8292906
102877486	102877509	12	+	27260156	PANC1	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.09032523569088691	[261]	[200,262,308,194]	1	hSpCas9	negative selection	8292907
102894747	102894770	12	+	27260156	PANC1	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.1587859240227708	[588]	[558,785,465,494]	2	hSpCas9	negative selection	8292908
102912791	102912814	12	+	27260156	PANC0813	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.09324780156569124	[1001]	[1154,1225,1348,1279]	1	hSpCas9	negative selection	8349904
102912790	102912813	12	-	27260156	PANC0813	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.5926871053425533	[228]	[590,240,432,375]	8	hSpCas9	negative selection	8349905
102877487	102877510	12	-	27260156	PANC0813	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.40002227226854403	[381]	[482,643,715,518]	6	hSpCas9	negative selection	8349906
102894860	102894883	12	+	27260156	PANC0813	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.521000787709589	[55]	[130,77,64,105]	8	hSpCas9	negative selection	8414157
102877486	102877509	12	+	27260156	PANC0813	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	-0.40099571006063583	[261]	[238,298,176,217]	-6	hSpCas9	negative selection	8414158
102894747	102894770	12	+	27260156	PANC0813	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.21768623156352934	[588]	[877,624,1151,582]	3	hSpCas9	negative selection	8414159
102912791	102912814	12	+	27260156	RDES	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.47654157290814725	[1001]	[1352,1379,1476,2337]	7	hSpCas9	negative selection	8471155
102912790	102912813	12	-	27260156	RDES	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.4422639974978213	[228]	[311,343,327,461]	7	hSpCas9	negative selection	8471156
102877487	102877510	12	-	27260156	RDES	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	-0.09342691006027137	[381]	[451,381,355,437]	-1	hSpCas9	negative selection	8471157
102894860	102894883	12	+	27260156	RDES	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.4047777926654863	[55]	[64,114,54,106]	6	hSpCas9	negative selection	8535408
102877486	102877509	12	+	27260156	RDES	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.2042583150689301	[261]	[279,333,282,520]	3	hSpCas9	negative selection	8535409
102894747	102894770	12	+	27260156	RDES	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.6183735875938228	[588]	[758,970,1129,1394]	8	hSpCas9	negative selection	8535410
102912791	102912814	12	+	27260156	PC3	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.005583965091049192	[1001]	[660,879,1309,1348]	0	hSpCas9	negative selection	8592406
102912790	102912813	12	-	27260156	PC3	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.2903293196707366	[228]	[180,195,430,392]	6	hSpCas9	negative selection	8592407
102877487	102877510	12	-	27260156	PC3	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.18759800169037408	[381]	[301,451,533,497]	4	hSpCas9	negative selection	8592408
102894860	102894883	12	+	27260156	PC3	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.28073273088651973	[55]	[67,54,48,82]	6	hSpCas9	negative selection	8656659
102877486	102877509	12	+	27260156	PC3	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	-0.0385278442228002	[261]	[181,175,493,267]	-1	hSpCas9	negative selection	8656660
102894747	102894770	12	+	27260156	PC3	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.07706433501330279	[588]	[417,850,652,573]	1	hSpCas9	negative selection	8656661
102912791	102912814	12	+	27260156	PATU8988T	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.26688644051502086	[1001]	[1024,994,1481,1134]	4	hSpCas9	negative selection	8713657
102912790	102912813	12	-	27260156	PATU8988T	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.11678381835228213	[228]	[164,313,203,287]	2	hSpCas9	negative selection	8713658
102877487	102877510	12	-	27260156	PATU8988T	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.2129132313815219	[381]	[362,319,508,514]	3	hSpCas9	negative selection	8713659
102894860	102894883	12	+	27260156	PATU8988T	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	1.0394840500367462	[55]	[72,200,47,133]	9	hSpCas9	negative selection	8777910
102877486	102877509	12	+	27260156	PATU8988T	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	-0.6975504075389025	[261]	[119,160,171,172]	-8	hSpCas9	negative selection	8777911
102894747	102894770	12	+	27260156	PATU8988T	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.34743496339634977	[588]	[859,629,754,634]	6	hSpCas9	negative selection	8777912
102912791	102912814	12	+	27260156	T47D	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.11859375141309036	[1001]	[1353,1135,1338,1249]	2	hSpCas9	negative selection	8834908
102912790	102912813	12	-	27260156	T47D	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.19878496492484066	[228]	[300,215,344,371]	4	hSpCas9	negative selection	8834909
102877487	102877510	12	-	27260156	T47D	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	-0.06419429173166674	[381]	[492,377,433,400]	-1	hSpCas9	negative selection	8834910
102894860	102894883	12	+	27260156	T47D	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.5444569581011605	[55]	[107,93,101,75]	9	hSpCas9	negative selection	8899161
102877486	102877509	12	+	27260156	T47D	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.11942328012544312	[261]	[311,277,357,383]	2	hSpCas9	negative selection	8899162
102894747	102894770	12	+	27260156	T47D	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.3598563898647556	[588]	[954,809,890,871]	7	hSpCas9	negative selection	8899163
102912791	102912814	12	+	27260156	SU8686	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.05924931026345215	[1001]	[910,896,1235,1143]	1	hSpCas9	negative selection	8956159
102912790	102912813	12	-	27260156	SU8686	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.7262858430598373	[228]	[286,349,501,377]	9	hSpCas9	negative selection	8956160
102877487	102877510	12	-	27260156	SU8686	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.5859056043088597	[381]	[440,519,604,755]	8	hSpCas9	negative selection	8956161
102894860	102894883	12	+	27260156	SU8686	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	-0.22893974141081186	[55]	[51,42,53,38]	-4	hSpCas9	negative selection	9020412
102877486	102877509	12	+	27260156	SU8686	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.06698941185773155	[261]	[217,254,295,336]	1	hSpCas9	negative selection	9020413
102894747	102894770	12	+	27260156	SU8686	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.2778561963800848	[588]	[621,650,831,748]	5	hSpCas9	negative selection	9020414
102912791	102912814	12	+	27260156	SKES1	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.1362755481773259	[1001]	[1182,1059,1108,1043]	3	hSpCas9	negative selection	9077410
102912790	102912813	12	-	27260156	SKES1	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.5795055246582337	[228]	[530,322,255,283]	9	hSpCas9	negative selection	9077411
102877487	102877510	12	-	27260156	SKES1	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.0943174639048164	[381]	[414,468,316,428]	2	hSpCas9	negative selection	9077412
102894860	102894883	12	+	27260156	SKES1	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.7401176673713974	[55]	[57,180,71,69]	9	hSpCas9	negative selection	9141663
102877486	102877509	12	+	27260156	SKES1	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.15578820602407017	[261]	[349,303,277,244]	3	hSpCas9	negative selection	9141664
102894747	102894770	12	+	27260156	SKES1	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.3124143791418124	[588]	[677,784,724,722]	6	hSpCas9	negative selection	9141665
102912791	102912814	12	+	27260156	TOV112D	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.13945703412925514	[1001]	[1017,1728,934,889]	2	hSpCas9	negative selection	9198661
102912790	102912813	12	-	27260156	TOV112D	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.08686065882783689	[228]	[279,265,209,226]	1	hSpCas9	negative selection	9198662
102877487	102877510	12	-	27260156	TOV112D	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.027998964310066987	[381]	[397,364,429,361]	0	hSpCas9	negative selection	9198663
102894860	102894883	12	+	27260156	TOV112D	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	1.1787262488330625	[55]	[348,67,45,50]	9	hSpCas9	negative selection	9262914
102877486	102877509	12	+	27260156	TOV112D	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.1111451226056287	[261]	[174,188,313,418]	2	hSpCas9	negative selection	9262915
102894747	102894770	12	+	27260156	TOV112D	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.332902575287843	[588]	[521,1007,872,617]	6	hSpCas9	negative selection	9262916
102912791	102912814	12	+	27260156	TC71	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.10910218252549697	[1001]	[971,1256,1137,1278]	2	hSpCas9	negative selection	9319912
102912790	102912813	12	-	27260156	TC71	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.3996567233777987	[228]	[430,291,271,297]	8	hSpCas9	negative selection	9319913
102877487	102877510	12	-	27260156	TC71	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.3545215476757535	[381]	[545,503,467,580]	8	hSpCas9	negative selection	9319914
102894860	102894883	12	+	27260156	TC71	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.6303472358290967	[55]	[96,115,70,87]	9	hSpCas9	negative selection	9384165
102877486	102877509	12	+	27260156	TC71	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	0.19170784520939632	[261]	[383,282,338,271]	5	hSpCas9	negative selection	9384166
102894747	102894770	12	+	27260156	TC71	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.024766828635928828	[588]	[633,508,767,654]	0	hSpCas9	negative selection	9384167
102912791	102912814	12	+	27260156	TC32	viability	CTCAAATAAGCGCAATACTTTGG	PAH	ENSG00000171759	0.41688842950770333	[1001]	[1291,915,1568,1359]	7	hSpCas9	negative selection	9441163
102912790	102912813	12	-	27260156	TC32	viability	CAAAGTATTGCGCTTATTTGAGG	PAH	ENSG00000171759	0.5326892727609742	[228]	[322,154,455,380]	8	hSpCas9	negative selection	9441164
102877487	102877510	12	-	27260156	TC32	viability	GCCAATCAGATTCTCAGCTATGG	PAH	ENSG00000171759	0.1685907947387525	[381]	[373,286,577,430]	3	hSpCas9	negative selection	9441165
102894860	102894883	12	+	27260156	TC32	viability	TCATCTTTCTTTAAACGAGAAGG	PAH	ENSG00000171759	0.6616911632841163	[55]	[80,92,60,84]	9	hSpCas9	negative selection	9505416
102877486	102877509	12	+	27260156	TC32	viability	TCCATAGCTGAGAATCTGATTGG	PAH	ENSG00000171759	-0.03583845719480516	[261]	[216,157,371,257]	0	hSpCas9	negative selection	9505417
102894747	102894770	12	+	27260156	TC32	viability	TCTTATCTCGTGAAAGCTCATGG	PAH	ENSG00000171759	0.6605175938266756	[588]	[732,912,719,1062]	9	hSpCas9	negative selection	9505418
102852864	102852887	12	+	27869803	HPAFII	viability after 27 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	0.7613179376443447	[75]	[124,19,NaN]	6	hSpCas9	negative selection	9544798
102855310	102855333	12	-	27869803	HPAFII	viability after 27 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-0.9189672355421767	[596]	[165,165,NaN]	-6	hSpCas9	negative selection	9544799
102866629	102866652	12	+	27869803	HPAFII	viability after 27 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	1.2686173722107705	[164]	[256,168,NaN]	9	hSpCas9	negative selection	9544800
102877446	102877469	12	+	27869803	HPAFII	viability after 27 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	0.3847173452492787	[831]	[773,401,NaN]	3	hSpCas9	negative selection	9544801
102894822	102894845	12	+	27869803	HPAFII	viability after 27 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.37701437353198264	[291]	[260,147,NaN]	3	hSpCas9	negative selection	9544802
102917070	102917093	12	-	27869803	HPAFII	viability after 27 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.7097348223081652	[119]	[166,49,NaN]	6	hSpCas9	negative selection	9544803
102852864	102852887	12	+	27869803	HPAFII	viability after 15 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	0.09449473400714403	[75]	[175,31,NaN]	1	hSpCas9	negative selection	9627247
102855310	102855333	12	-	27869803	HPAFII	viability after 15 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-1.5154439943217806	[596]	[356,141,NaN]	-8	hSpCas9	negative selection	9627248
102866629	102866652	12	+	27869803	HPAFII	viability after 15 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	1.4256293034578666	[164]	[640,373,NaN]	9	hSpCas9	negative selection	9627249
102877446	102877469	12	+	27869803	HPAFII	viability after 15 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	-0.3096255425861185	[831]	[1067,505,NaN]	-3	hSpCas9	negative selection	9627250
102894822	102894845	12	+	27869803	HPAFII	viability after 15 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.53163756775937	[291]	[629,343,NaN]	6	hSpCas9	negative selection	9627251
102917070	102917093	12	-	27869803	HPAFII	viability after 15 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.5826483229928379	[119]	[276,140,NaN]	6	hSpCas9	negative selection	9627252
102852864	102852887	12	+	27869803	ASPC1	viability after 36 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	0.20713892310226112	[201]	[201,6,54]	2	hSpCas9	negative selection	9709696
102855310	102855333	12	-	27869803	ASPC1	viability after 36 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-0.09162155411072126	[1367]	[629,418,338]	-1	hSpCas9	negative selection	9709697
102866629	102866652	12	+	27869803	ASPC1	viability after 36 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.613862556859405	[490]	[218,498,101]	6	hSpCas9	negative selection	9709698
102877446	102877469	12	+	27869803	ASPC1	viability after 36 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	0.4050201008805341	[1830]	[1170,443,928]	4	hSpCas9	negative selection	9709699
102894822	102894845	12	+	27869803	ASPC1	viability after 36 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.8650877838736033	[699]	[671,370,339]	8	hSpCas9	negative selection	9709700
102917070	102917093	12	-	27869803	ASPC1	viability after 36 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.9716615266711881	[351]	[453,182,134]	8	hSpCas9	negative selection	9709701
102852864	102852887	12	+	27869803	PATU8988S	viability after 35 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	0.9499210015206285	[177]	[132,143,NaN]	8	hSpCas9	negative selection	9792145
102855310	102855333	12	-	27869803	PATU8988S	viability after 35 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-0.0745613932524789	[1240]	[534,413,NaN]	-1	hSpCas9	negative selection	9792146
102866629	102866652	12	+	27869803	PATU8988S	viability after 35 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.2183306415528998	[488]	[282,174,NaN]	2	hSpCas9	negative selection	9792147
102877446	102877469	12	+	27869803	PATU8988S	viability after 35 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	0.33034610523014574	[1351]	[741,626,NaN]	4	hSpCas9	negative selection	9792148
102894822	102894845	12	+	27869803	PATU8988S	viability after 35 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.42957258504452944	[621]	[291,382,NaN]	5	hSpCas9	negative selection	9792149
102917070	102917093	12	-	27869803	PATU8988S	viability after 35 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.512217122777401	[376]	[240,191,NaN]	6	hSpCas9	negative selection	9792150
102852864	102852887	12	+	27869803	PATU8988S	viability after 31 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	0.429035843987263	[177]	[84,108,NaN]	5	hSpCas9	negative selection	9874594
102855310	102855333	12	-	27869803	PATU8988S	viability after 31 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-0.21038546376059286	[1240]	[300,588,NaN]	-2	hSpCas9	negative selection	9874595
102866629	102866652	12	+	27869803	PATU8988S	viability after 31 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	0.5449406360298006	[488]	[265,307,NaN]	6	hSpCas9	negative selection	9874596
102877446	102877469	12	+	27869803	PATU8988S	viability after 31 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	0.6481939543004922	[1351]	[660,1078,NaN]	7	hSpCas9	negative selection	9874597
102894822	102894845	12	+	27869803	PATU8988S	viability after 31 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	-0.05759018906431179	[621]	[203,281,NaN]	0	hSpCas9	negative selection	9874598
102917070	102917093	12	-	27869803	PATU8988S	viability after 31 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.6218334046942798	[376]	[262,190,NaN]	7	hSpCas9	negative selection	9874599
102852864	102852887	12	+	27869803	HPAFII	viability after 35 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	1.2592097992877842	[75]	[164,9,NaN]	8	hSpCas9	negative selection	9957043
102855310	102855333	12	-	27869803	HPAFII	viability after 35 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-1.5532748808456844	[596]	[62,147,NaN]	-7	hSpCas9	negative selection	9957044
102866629	102866652	12	+	27869803	HPAFII	viability after 35 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	1.214002774023423	[164]	[213,170,NaN]	7	hSpCas9	negative selection	9957045
102877446	102877469	12	+	27869803	HPAFII	viability after 35 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	0.34779121791426215	[831]	[694,356,NaN]	2	hSpCas9	negative selection	9957046
102894822	102894845	12	+	27869803	HPAFII	viability after 35 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.9127426514917453	[291]	[401,138,NaN]	6	hSpCas9	negative selection	9957047
102917070	102917093	12	-	27869803	HPAFII	viability after 35 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	1.1741454560144782	[119]	[193,72,NaN]	7	hSpCas9	negative selection	9957048
102852864	102852887	12	+	27869803	HPAFII	viability after 31 days	AGTGGAAGACTCGGAAGGCCAGG	PAH	ENSG00000171759	0.7094172490678596	[75]	[130,2,NaN]	5	hSpCas9	negative selection	10039492
102855310	102855333	12	-	27869803	HPAFII	viability after 31 days	TGGGCAGCCCATCCCTCGAGTGG	PAH	ENSG00000171759	-1.5455961924890471	[596]	[64,168,NaN]	-7	hSpCas9	negative selection	10039493
102866629	102866652	12	+	27869803	HPAFII	viability after 31 days	TTCCGTCTTGCACGGTACACAGG	PAH	ENSG00000171759	1.4484123960622963	[164]	[290,210,NaN]	9	hSpCas9	negative selection	10039494
102877446	102877469	12	+	27869803	HPAFII	viability after 31 days	CGGGCCATGGACTCACAGGGTGG	PAH	ENSG00000171759	0.04233172815109798	[831]	[599,350,NaN]	0	hSpCas9	negative selection	10039495
102894822	102894845	12	+	27869803	HPAFII	viability after 31 days	GCAGGCTACGTTTATCCAAATGG	PAH	ENSG00000171759	0.7405252771657778	[291]	[313,229,NaN]	5	hSpCas9	negative selection	10039496
102917070	102917093	12	-	27869803	HPAFII	viability after 31 days	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	1.304372805628377	[119]	[262,60,NaN]	8	hSpCas9	negative selection	10039497
102917104	102917127	12	+	28162770	P31FUJ	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	0.3163150973600555	[325]	[476]	3	hSpCas9	negative selection	10206375
102917070	102917093	12	-	28162770	P31FUJ	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.26162274989317513	[410]	[578]	3	hSpCas9	negative selection	10206376
102877482	102877505	12	-	28162770	P31FUJ	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	0.12186267688498353	[243]	[311]	1	hSpCas9	negative selection	10206377
102917085	102917108	12	+	28162770	P31FUJ	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	0.5610752137256849	[168]	[292]	6	hSpCas9	negative selection	10206378
102894876	102894899	12	+	28162770	P31FUJ	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.2533183929259477	[296]	[415]	2	hSpCas9	negative selection	10206379
102852912	102852935	12	+	28162770	P31FUJ	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	0.7993782013347711	[132]	[271]	8	hSpCas9	negative selection	10206380
102852886	102852909	12	+	28162770	P31FUJ	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.5432226038864825	[531]	[910]	6	hSpCas9	negative selection	10206381
102843727	102843750	12	+	28162770	P31FUJ	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	0.3046147120389848	[400]	[581]	3	hSpCas9	negative selection	10206382
102840455	102840478	12	-	28162770	P31FUJ	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	0.32161123294717076	[349]	[513]	3	hSpCas9	negative selection	10206383
102917118	102917141	12	-	28162770	P31FUJ	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	0.8891883199642318	[186]	[406]	8	hSpCas9	negative selection	10206384
102917104	102917127	12	+	28162770	TF1	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	NaN	[NaN]	[356]	1	hSpCas9	negative selection	10375741
102917070	102917093	12	-	28162770	TF1	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	NaN	[NaN]	[423]	1	hSpCas9	negative selection	10375742
102877482	102877505	12	-	28162770	TF1	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	NaN	[NaN]	[144]	1	hSpCas9	negative selection	10375743
102917085	102917108	12	+	28162770	TF1	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	NaN	[NaN]	[350]	1	hSpCas9	negative selection	10375744
102894876	102894899	12	+	28162770	TF1	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	NaN	[NaN]	[405]	1	hSpCas9	negative selection	10375745
102852912	102852935	12	+	28162770	TF1	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	NaN	[NaN]	[205]	1	hSpCas9	negative selection	10375746
102852886	102852909	12	+	28162770	TF1	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	NaN	[NaN]	[591]	1	hSpCas9	negative selection	10375747
102843727	102843750	12	+	28162770	TF1	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	NaN	[NaN]	[403]	1	hSpCas9	negative selection	10375748
102840455	102840478	12	-	28162770	TF1	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	NaN	[NaN]	[445]	1	hSpCas9	negative selection	10375749
102917118	102917141	12	-	28162770	TF1	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	NaN	[NaN]	[236]	1	hSpCas9	negative selection	10375750
102917104	102917127	12	+	28162770	SKM1	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	-0.42607302169086636	[94]	[124]	-4	hSpCas9	negative selection	10545107
102917070	102917093	12	-	28162770	SKM1	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.683068002119311	[98]	[280]	6	hSpCas9	negative selection	10545108
102877482	102877505	12	-	28162770	SKM1	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	-0.191647294486835	[72]	[112]	-2	hSpCas9	negative selection	10545109
102917085	102917108	12	+	28162770	SKM1	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	0.7471068514983137	[60]	[180]	7	hSpCas9	negative selection	10545110
102894876	102894899	12	+	28162770	SKM1	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.3450058200380125	[109]	[246]	3	hSpCas9	negative selection	10545111
102852912	102852935	12	+	28162770	SKM1	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	0.17799830197799466	[63]	[127]	1	hSpCas9	negative selection	10545112
102852886	102852909	12	+	28162770	SKM1	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	-0.09476764187357267	[118]	[196]	-1	hSpCas9	negative selection	10545113
102843727	102843750	12	+	28162770	SKM1	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	1.2731555350183346	[76]	[328]	9	hSpCas9	negative selection	10545114
102840455	102840478	12	-	28162770	SKM1	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	0.18733616655733082	[76]	[154]	1	hSpCas9	negative selection	10545115
102917118	102917141	12	-	28162770	SKM1	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	1.4361504864320422	[36]	[176]	9	hSpCas9	negative selection	10545116
102917104	102917127	12	+	28162770	SKM1	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	-0.42607302169086636	[94]	[124]	-4	hSpCas9	negative selection	10714473
102917070	102917093	12	-	28162770	SKM1	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.683068002119311	[98]	[280]	6	hSpCas9	negative selection	10714474
102877482	102877505	12	-	28162770	SKM1	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	-0.191647294486835	[72]	[112]	-2	hSpCas9	negative selection	10714475
102917085	102917108	12	+	28162770	SKM1	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	0.7471068514983137	[60]	[180]	7	hSpCas9	negative selection	10714476
102894876	102894899	12	+	28162770	SKM1	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.3450058200380125	[109]	[246]	3	hSpCas9	negative selection	10714477
102852912	102852935	12	+	28162770	SKM1	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	0.17799830197799466	[63]	[127]	1	hSpCas9	negative selection	10714478
102852886	102852909	12	+	28162770	SKM1	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	-0.09476764187357267	[118]	[196]	-1	hSpCas9	negative selection	10714479
102843727	102843750	12	+	28162770	SKM1	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	1.2731555350183346	[76]	[328]	9	hSpCas9	negative selection	10714480
102840455	102840478	12	-	28162770	SKM1	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	0.18733616655733082	[76]	[154]	1	hSpCas9	negative selection	10714481
102917118	102917141	12	-	28162770	SKM1	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	1.4361504864320422	[36]	[176]	9	hSpCas9	negative selection	10714482
102917104	102917127	12	+	28162770	PL21	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	0.3843724526155159	[300]	[170]	3	hSpCas9	negative selection	10883839
102917070	102917093	12	-	28162770	PL21	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.4206045872546538	[320]	[186]	3	hSpCas9	negative selection	10883840
102877482	102877505	12	-	28162770	PL21	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	0.5430273280123286	[204]	[129]	5	hSpCas9	negative selection	10883841
102917085	102917108	12	+	28162770	PL21	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	-0.7420397311223376	[268]	[69]	-5	hSpCas9	negative selection	10883842
102894876	102894899	12	+	28162770	PL21	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.887549384181294	[384]	[309]	7	hSpCas9	negative selection	10883843
102852912	102852935	12	+	28162770	PL21	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	0.32072975530290854	[194]	[105]	3	hSpCas9	negative selection	10883844
102852886	102852909	12	+	28162770	PL21	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.5914373926988932	[336]	[220]	5	hSpCas9	negative selection	10883845
102843727	102843750	12	+	28162770	PL21	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	0.7996016849055914	[197]	[149]	6	hSpCas9	negative selection	10883846
102840455	102840478	12	-	28162770	PL21	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	0.5339953575128109	[264]	[166]	4	hSpCas9	negative selection	10883847
102917118	102917141	12	-	28162770	PL21	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	-1.2428038813594084	[173]	[31]	-7	hSpCas9	negative selection	10883848
102917104	102917127	12	+	28162770	P31FUJ	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	0.3163150973600555	[325]	[476]	3	hSpCas9	negative selection	11053205
102917070	102917093	12	-	28162770	P31FUJ	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.26162274989317513	[410]	[578]	3	hSpCas9	negative selection	11053206
102877482	102877505	12	-	28162770	P31FUJ	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	0.12186267688498353	[243]	[311]	1	hSpCas9	negative selection	11053207
102917085	102917108	12	+	28162770	P31FUJ	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	0.5610752137256849	[168]	[292]	6	hSpCas9	negative selection	11053208
102894876	102894899	12	+	28162770	P31FUJ	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.2533183929259477	[296]	[415]	2	hSpCas9	negative selection	11053209
102852912	102852935	12	+	28162770	P31FUJ	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	0.7993782013347711	[132]	[271]	8	hSpCas9	negative selection	11053210
102852886	102852909	12	+	28162770	P31FUJ	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.5432226038864825	[531]	[910]	6	hSpCas9	negative selection	11053211
102843727	102843750	12	+	28162770	P31FUJ	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	0.3046147120389848	[400]	[581]	3	hSpCas9	negative selection	11053212
102840455	102840478	12	-	28162770	P31FUJ	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	0.32161123294717076	[349]	[513]	3	hSpCas9	negative selection	11053213
102917118	102917141	12	-	28162770	P31FUJ	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	0.8891883199642318	[186]	[406]	8	hSpCas9	negative selection	11053214
102917104	102917127	12	+	28162770	OCIAML5	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	0.42158150899464875	[157]	[381]	3	hSpCas9	negative selection	11222571
102917070	102917093	12	-	28162770	OCIAML5	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.2161909575395642	[257]	[540]	1	hSpCas9	negative selection	11222572
102877482	102877505	12	-	28162770	OCIAML5	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	0.7224035560395169	[137]	[410]	6	hSpCas9	negative selection	11222573
102917085	102917108	12	+	28162770	OCIAML5	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	0.22482702867615514	[136]	[288]	1	hSpCas9	negative selection	11222574
102894876	102894899	12	+	28162770	OCIAML5	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.7688368109262729	[184]	[568]	6	hSpCas9	negative selection	11222575
102852912	102852935	12	+	28162770	OCIAML5	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	-0.24147826246734644	[92]	[141]	-2	hSpCas9	negative selection	11222576
102852886	102852909	12	+	28162770	OCIAML5	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.1629877748582922	[285]	[577]	1	hSpCas9	negative selection	11222577
102843727	102843750	12	+	28162770	OCIAML5	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	0.5375617643871232	[178]	[468]	5	hSpCas9	negative selection	11222578
102840455	102840478	12	-	28162770	OCIAML5	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	-0.22962936472417794	[227]	[350]	-2	hSpCas9	negative selection	11222579
102917118	102917141	12	-	28162770	OCIAML5	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	0.5592090096186477	[143]	[382]	5	hSpCas9	negative selection	11222580
102917104	102917127	12	+	28162770	EOL1	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	0.5905680762539268	[570]	[452]	5	hSpCas9	negative selection	11391937
102917070	102917093	12	-	28162770	EOL1	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.5224493279991889	[369]	[279]	5	hSpCas9	negative selection	11391938
102877482	102877505	12	-	28162770	EOL1	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	0.8954853059680717	[350]	[343]	7	hSpCas9	negative selection	11391939
102917085	102917108	12	+	28162770	EOL1	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	-0.24181061485158553	[403]	[179]	-2	hSpCas9	negative selection	11391940
102894876	102894899	12	+	28162770	EOL1	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.6187393420464491	[622]	[503]	5	hSpCas9	negative selection	11391941
102852912	102852935	12	+	28162770	EOL1	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	0.2171552927876754	[337]	[206]	2	hSpCas9	negative selection	11391942
102852886	102852909	12	+	28162770	EOL1	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	-0.17902033897224479	[562]	[261]	-1	hSpCas9	negative selection	11391943
102843727	102843750	12	+	28162770	EOL1	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	0.2779974726265465	[334]	[213]	2	hSpCas9	negative selection	11391944
102840455	102840478	12	-	28162770	EOL1	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	0.7204375071346842	[378]	[328]	6	hSpCas9	negative selection	11391945
102917118	102917141	12	-	28162770	EOL1	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	-0.7351824975525938	[296]	[93]	-5	hSpCas9	negative selection	11391946
102917104	102917127	12	+	28162770	MOLM13	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	1.3072065324071152	[388]	[695]	8	hSpCas9	negative selection	11561303
102917070	102917093	12	-	28162770	MOLM13	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	1.0428677936931132	[579]	[863]	7	hSpCas9	negative selection	11561304
102877482	102877505	12	-	28162770	MOLM13	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	0.3200439135731848	[307]	[277]	2	hSpCas9	negative selection	11561305
102917085	102917108	12	+	28162770	MOLM13	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	0.5410557941065504	[345]	[363]	4	hSpCas9	negative selection	11561306
102894876	102894899	12	+	28162770	MOLM13	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.899070073311249	[510]	[688]	7	hSpCas9	negative selection	11561307
102852912	102852935	12	+	28162770	MOLM13	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	1.0280902287880096	[332]	[490]	7	hSpCas9	negative selection	11561308
102852886	102852909	12	+	28162770	MOLM13	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.817287079616347	[488]	[622]	6	hSpCas9	negative selection	11561309
102843727	102843750	12	+	28162770	MOLM13	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	0.20575920328089906	[318]	[265]	1	hSpCas9	negative selection	11561310
102840455	102840478	12	-	28162770	MOLM13	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	-0.17764199549412396	[753]	[481]	-1	hSpCas9	negative selection	11561311
102917118	102917141	12	-	28162770	MOLM13	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	0.07557195876581868	[209]	[159]	0	hSpCas9	negative selection	11561312
102917104	102917127	12	+	28162770	HEL	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	0.3952772300870242	[386]	[325]	3	hSpCas9	negative selection	11730669
102917070	102917093	12	-	28162770	HEL	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.13228176764283095	[499]	[350]	1	hSpCas9	negative selection	11730670
102877482	102877505	12	-	28162770	HEL	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	0.7472947630429467	[305]	[328]	6	hSpCas9	negative selection	11730671
102917085	102917108	12	+	28162770	HEL	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	0.01470760938731469	[322]	[208]	0	hSpCas9	negative selection	11730672
102894876	102894899	12	+	28162770	HEL	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.5124308096546262	[439]	[401]	4	hSpCas9	negative selection	11730673
102852912	102852935	12	+	28162770	HEL	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	1.358662010604676	[220]	[362]	9	hSpCas9	negative selection	11730674
102852886	102852909	12	+	28162770	HEL	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.4946401930112231	[409]	[369]	4	hSpCas9	negative selection	11730675
102843727	102843750	12	+	28162770	HEL	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	-1.0223940174047825	[332]	[104]	-6	hSpCas9	negative selection	11730676
102840455	102840478	12	-	28162770	HEL	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	0.2772571571957456	[495]	[384]	2	hSpCas9	negative selection	11730677
102917118	102917141	12	-	28162770	HEL	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	-0.7699547268101877	[204]	[76]	-5	hSpCas9	negative selection	11730678
102917104	102917127	12	+	28162770	MV411	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	0.8188170792310066	[248]	[369]	7	hSpCas9	negative selection	11900035
102917070	102917093	12	-	28162770	MV411	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	1.0734081510077265	[285]	[506]	8	hSpCas9	negative selection	11900036
102877482	102877505	12	-	28162770	MV411	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	-0.06189050732495352	[227]	[183]	0	hSpCas9	negative selection	11900037
102917085	102917108	12	+	28162770	MV411	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	0.5953608542030822	[219]	[279]	5	hSpCas9	negative selection	11900038
102894876	102894899	12	+	28162770	MV411	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.509814842034091	[365]	[438]	4	hSpCas9	negative selection	11900039
102852912	102852935	12	+	28162770	MV411	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	0.24743755078277532	[202]	[202]	2	hSpCas9	negative selection	11900040
102852886	102852909	12	+	28162770	MV411	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.3583216569022327	[362]	[391]	3	hSpCas9	negative selection	11900041
102843727	102843750	12	+	28162770	MV411	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	0.5706589626916583	[222]	[278]	5	hSpCas9	negative selection	11900042
102840455	102840478	12	-	28162770	MV411	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	-0.03686547180466976	[245]	[201]	0	hSpCas9	negative selection	11900043
102917118	102917141	12	-	28162770	MV411	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	0.25637067555278303	[160]	[161]	2	hSpCas9	negative selection	11900044
102917104	102917127	12	+	28162770	MONOMAC1	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	0.3821200319803969	[165]	[247]	4	hSpCas9	negative selection	12069401
102917070	102917093	12	-	28162770	MONOMAC1	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	1.2121715734170926	[185]	[493]	9	hSpCas9	negative selection	12069402
102877482	102877505	12	-	28162770	MONOMAC1	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	-0.22851507853272182	[138]	[135]	-2	hSpCas9	negative selection	12069403
102917085	102917108	12	+	28162770	MONOMAC1	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	0.006126102796841448	[204]	[235]	0	hSpCas9	negative selection	12069404
102894876	102894899	12	+	28162770	MONOMAC1	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.3469372422107636	[237]	[346]	3	hSpCas9	negative selection	12069405
102852912	102852935	12	+	28162770	MONOMAC1	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	-0.234269753258529	[156]	[152]	-2	hSpCas9	negative selection	12069406
102852886	102852909	12	+	28162770	MONOMAC1	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.4753884949119418	[255]	[407]	5	hSpCas9	negative selection	12069407
102843727	102843750	12	+	28162770	MONOMAC1	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	-0.813708207508048	[183]	[119]	-6	hSpCas9	negative selection	12069408
102840455	102840478	12	-	28162770	MONOMAC1	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	0.4886196532810755	[165]	[266]	5	hSpCas9	negative selection	12069409
102917118	102917141	12	-	28162770	MONOMAC1	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	0.17562204994873845	[94]	[122]	1	hSpCas9	negative selection	12069410
102917104	102917127	12	+	28162770	OCIAML2	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	0.6149459064639127	[44]	[381]	6	hSpCas9	negative selection	12238767
102917070	102917093	12	-	28162770	OCIAML2	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.9384408322748692	[52]	[562]	8	hSpCas9	negative selection	12238768
102877482	102877505	12	-	28162770	OCIAML2	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	-0.9831838304352671	[50]	[142]	-6	hSpCas9	negative selection	12238769
102917085	102917108	12	+	28162770	OCIAML2	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	0.5136028588995221	[45]	[363]	5	hSpCas9	negative selection	12238770
102894876	102894899	12	+	28162770	OCIAML2	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.54873549962477	[73]	[599]	5	hSpCas9	negative selection	12238771
102852912	102852935	12	+	28162770	OCIAML2	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	0.03600431479403521	[40]	[232]	0	hSpCas9	negative selection	12238772
102852886	102852909	12	+	28162770	OCIAML2	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.505523432803471	[60]	[479]	5	hSpCas9	negative selection	12238773
102843727	102843750	12	+	28162770	OCIAML2	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	1.3043843767732242	[28]	[396]	9	hSpCas9	negative selection	12238774
102840455	102840478	12	-	28162770	OCIAML2	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	0.0047081843044967375	[40]	[227]	0	hSpCas9	negative selection	12238775
102917118	102917141	12	-	28162770	OCIAML2	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	0.9837485656688507	[25]	[284]	8	hSpCas9	negative selection	12238776
102917104	102917127	12	+	28162770	OCIAML3	viability	TGGGTTTTCCAGGACCGCAGTGG	PAH	ENSG00000171759	1.0717158723608293	[54]	[348]	8	hSpCas9	negative selection	12408133
102917070	102917093	12	-	28162770	OCIAML3	viability	GAAACTCTCTGACTTTGGACAGG	PAH	ENSG00000171759	0.1894397422468408	[112]	[388]	1	hSpCas9	negative selection	12408134
102877482	102877505	12	-	28162770	OCIAML3	viability	TCAGATTCTCAGCTATGGAGCGG	PAH	ENSG00000171759	0.7220198531235148	[48]	[243]	6	hSpCas9	negative selection	12408135
102917085	102917108	12	+	28162770	OCIAML3	viability	AGAGTTTCCTGCCCAAGCCTGGG	PAH	ENSG00000171759	-0.43788843840688124	[69]	[155]	-3	hSpCas9	negative selection	12408136
102894876	102894899	12	+	28162770	OCIAML3	viability	GAGAAGGTCTAGATTCAATGTGG	PAH	ENSG00000171759	0.15194673706929784	[95]	[321]	1	hSpCas9	negative selection	12408137
102852912	102852935	12	+	28162770	OCIAML3	viability	GCAGGCCAGCCACAGGTCGGAGG	PAH	ENSG00000171759	-0.10435209969873427	[72]	[204]	-1	hSpCas9	negative selection	12408138
102852886	102852909	12	+	28162770	OCIAML3	viability	GCCACCCAAGAAATCCCGAGAGG	PAH	ENSG00000171759	0.4220046776644677	[111]	[452]	4	hSpCas9	negative selection	12408139
102843727	102843750	12	+	28162770	OCIAML3	viability	GCTGTCTTCTCCAGCTCCAGGGG	PAH	ENSG00000171759	0.43317718900206714	[91]	[374]	4	hSpCas9	negative selection	12408140
102840455	102840478	12	-	28162770	OCIAML3	viability	GCTACGACCCATACACCCAAAGG	PAH	ENSG00000171759	0.3962113388832515	[73]	[293]	3	hSpCas9	negative selection	12408141
102917118	102917141	12	-	28162770	OCIAML3	viability	GGGAGCCAGCATGTCCACTGCGG	PAH	ENSG00000171759	0.29212439511755794	[55]	[206]	2	hSpCas9	negative selection	12408142