Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 10298
• Symbol: PAK4
• Description: p21 (RAC1) activated kinase 4

DataSource: http://genomecrispr.dkfz.de/#!/results/PAK4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
39173748	39173771	19	-	26472758	Jiyoye	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-1.1136567817955672	[65]	[22]	-6	hSpCas9	negative selection	115550
39173904	39173927	19	-	26472758	Jiyoye	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	1.2411654300669444	[22]	[40]	7	hSpCas9	negative selection	115551
39173862	39173885	19	-	26472758	Jiyoye	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	-1.6278715655933276	[249]	[60]	-8	hSpCas9	negative selection	115552
39173967	39173990	19	+	26472758	Jiyoye	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	0.42311692537489476	[89]	[90]	3	hSpCas9	negative selection	115553
39177728	39177751	19	-	26472758	Jiyoye	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	0.7212839719339366	[36]	[45]	5	hSpCas9	negative selection	115554
39169559	39169582	19	+	26472758	Jiyoye	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-0.7627496199364389	[98]	[43]	-5	hSpCas9	negative selection	115555
39169588	39169611	19	-	26472758	Jiyoye	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	0.03371698597842898	[56]	[43]	0	hSpCas9	negative selection	115556
39169664	39169687	19	+	26472758	Jiyoye	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	3.214530303563477	[0]	[6]	9	hSpCas9	negative selection	115557
39169708	39169731	19	-	26472758	Jiyoye	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	-0.25940088476893475	[99]	[62]	-2	hSpCas9	negative selection	115558
39169726	39169749	19	+	26472758	Jiyoye	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.07308047073164237	[386]	[306]	0	hSpCas9	negative selection	115559
39173748	39173771	19	-	26472758	KBM7	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-1.2643658838475549	[233,204]	[63,23]	-7	hSpCas9	negative selection	306668
39173904	39173927	19	-	26472758	KBM7	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.3530251658668402	[327,349]	[209,200]	4	hSpCas9	negative selection	306669
39173862	39173885	19	-	26472758	KBM7	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	0.31236236421803076	[581,277]	[229,254]	3	hSpCas9	negative selection	306670
39173967	39173990	19	+	26472758	KBM7	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	0.48026462378012785	[341,324]	[327,121]	5	hSpCas9	negative selection	306671
39177728	39177751	19	-	26472758	KBM7	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	0.6331239014160571	[166,172]	[156,95]	7	hSpCas9	negative selection	306672
39169559	39169582	19	+	26472758	KBM7	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	0.09642015678919014	[272,191]	[117,112]	0	hSpCas9	negative selection	306673
39169588	39169611	19	-	26472758	KBM7	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	0.7805122958959638	[334,178]	[293,119]	8	hSpCas9	negative selection	306674
39169664	39169687	19	+	26472758	KBM7	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	1.1085657376300375	[37,15]	[9,40]	9	hSpCas9	negative selection	306675
39169708	39169731	19	-	26472758	KBM7	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	1.202578857267484	[412,333]	[575,245]	9	hSpCas9	negative selection	306676
39169726	39169749	19	+	26472758	KBM7	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.11718357101202992	[1711,1593]	[909,784]	1	hSpCas9	negative selection	306677
39173748	39173771	19	-	26472758	Raji	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-1.2660748601538447	[113]	[10]	-7	hSpCas9	negative selection	497786
39173904	39173927	19	-	26472758	Raji	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.018880237272573153	[178]	[40]	0	hSpCas9	negative selection	497787
39173862	39173885	19	-	26472758	Raji	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	0.039920567594860595	[196]	[46]	0	hSpCas9	negative selection	497788
39173967	39173990	19	+	26472758	Raji	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	0.7088341588833246	[86]	[32]	6	hSpCas9	negative selection	497789
39177728	39177751	19	-	26472758	Raji	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	1.43995887446047	[53]	[33]	9	hSpCas9	negative selection	497790
39169559	39169582	19	+	26472758	Raji	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-1.4161784206834134	[160]	[13]	-7	hSpCas9	negative selection	497791
39169588	39169611	19	-	26472758	Raji	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	-0.7141155690042745	[204]	[28]	-5	hSpCas9	negative selection	497792
39169664	39169687	19	+	26472758	Raji	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	-0.40718963745615877	[39]	[6]	-3	hSpCas9	negative selection	497793
39169708	39169731	19	-	26472758	Raji	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	0.6058370428400809	[251]	[88]	6	hSpCas9	negative selection	497794
39169726	39169749	19	+	26472758	Raji	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.27190854907332196	[802]	[224]	2	hSpCas9	negative selection	497795
39173748	39173771	19	-	26472758	K562	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-6.362911586083164	[194]	[1]	-9	hSpCas9	negative selection	688904
39173904	39173927	19	-	26472758	K562	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.36371765603879136	[173]	[188]	3	hSpCas9	negative selection	688905
39173862	39173885	19	-	26472758	K562	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	0.3620492216665464	[411]	[446]	3	hSpCas9	negative selection	688906
39173967	39173990	19	+	26472758	K562	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	0.6219241704486895	[330]	[429]	5	hSpCas9	negative selection	688907
39177728	39177751	19	-	26472758	K562	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	-0.5231351863331823	[142]	[83]	-3	hSpCas9	negative selection	688908
39169559	39169582	19	+	26472758	K562	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-2.6090326089806113	[317]	[43]	-8	hSpCas9	negative selection	688909
39169588	39169611	19	-	26472758	K562	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	-0.8561852132719585	[192]	[89]	-5	hSpCas9	negative selection	688910
39169664	39169687	19	+	26472758	K562	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	0.17730453180790962	[43]	[41]	1	hSpCas9	negative selection	688911
39169708	39169731	19	-	26472758	K562	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	-0.2656565614237174	[365]	[256]	-2	hSpCas9	negative selection	688912
39169726	39169749	19	+	26472758	K562	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.523293969188642	[1101]	[1336]	4	hSpCas9	negative selection	688913
39169546	39169569	19	+	26627737	DLD1	viability	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	0.07209207922539784	[1432]	[588,543,307]	0	hSpCas9	negative selection	804621
39173249	39173272	19	-	26627737	DLD1	viability	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	-0.33362157366694595	[416]	[152,68,88]	-3	hSpCas9	negative selection	804622
39173596	39173619	19	+	26627737	DLD1	viability	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-0.20820022092568824	[416]	[162,134,50]	-2	hSpCas9	negative selection	804623
39175043	39175066	19	+	26627737	DLD1	viability	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.03322666160437282	[1481]	[819,172,365]	0	hSpCas9	negative selection	804624
39175374	39175397	19	+	26627737	DLD1	viability	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	1.0929663542879111	[36]	[8,59,8]	8	hSpCas9	negative selection	804625
39176693	39176716	19	-	26627737	DLD1	viability	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	0.01775634646221602	[277]	[100,118,50]	0	hSpCas9	negative selection	804626
39169546	39169569	19	+	26627737	GBM cells	viability after 5 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	0.07699432507154125	[783]	[507,378]	1	hSpCas9	negative selection	886936
39173249	39173272	19	-	26627737	GBM cells	viability after 5 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	-0.41741875710815735	[192]	[83,70]	-6	hSpCas9	negative selection	886937
39173596	39173619	19	+	26627737	GBM cells	viability after 5 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	0.2382240480012846	[131]	[98,67]	4	hSpCas9	negative selection	886938
39175043	39175066	19	+	26627737	GBM cells	viability after 5 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	0.4573155493357064	[602]	[487,399]	7	hSpCas9	negative selection	886939
39175374	39175397	19	+	26627737	GBM cells	viability after 5 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	0.35834549352298284	[47]	[27,37]	5	hSpCas9	negative selection	886940
39176693	39176716	19	-	26627737	GBM cells	viability after 5 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	0.2925777233719624	[152]	[112,87]	4	hSpCas9	negative selection	886941
39169546	39169569	19	+	26627737	GBM cells	viability after 13 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	0.032898775386942525	[783]	[475,401]	0	hSpCas9	negative selection	969251
39173249	39173272	19	-	26627737	GBM cells	viability after 13 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	-0.00248730858621532	[192]	[146,69]	0	hSpCas9	negative selection	969252
39173596	39173619	19	+	26627737	GBM cells	viability after 13 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	0.4282960541350283	[131]	[86,103]	5	hSpCas9	negative selection	969253
39175043	39175066	19	+	26627737	GBM cells	viability after 13 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	0.09708786687366056	[602]	[387,318]	1	hSpCas9	negative selection	969254
39175374	39175397	19	+	26627737	GBM cells	viability after 13 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	0.06298733701062664	[47]	[24,28]	0	hSpCas9	negative selection	969255
39176693	39176716	19	-	26627737	GBM cells	viability after 13 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-0.5588657146283635	[152]	[73,41]	-6	hSpCas9	negative selection	969256
39169546	39169569	19	+	26627737	GBM cells	viability after 21 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-0.34072858611434875	[783]	[351,321]	-3	hSpCas9	negative selection	1051566
39173249	39173272	19	-	26627737	GBM cells	viability after 21 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	-0.9195418799736715	[192]	[56,53]	-7	hSpCas9	negative selection	1051567
39173596	39173619	19	+	26627737	GBM cells	viability after 21 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	0.42263727725279915	[131]	[104,87]	4	hSpCas9	negative selection	1051568
39175043	39175066	19	+	26627737	GBM cells	viability after 21 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	0.7710382804348686	[602]	[557,559]	7	hSpCas9	negative selection	1051569
39175374	39175397	19	+	26627737	GBM cells	viability after 21 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	0.8788968520528446	[47]	[48,46]	8	hSpCas9	negative selection	1051570
39176693	39176716	19	-	26627737	GBM cells	viability after 21 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-0.15004672742245795	[152]	[76,72]	-1	hSpCas9	negative selection	1051571
39169546	39169569	19	+	26627737	RPE1	viability after 9 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-0.7206520761786024	[2976]	[503,644]	-5	hSpCas9	negative selection	1133881
39173249	39173272	19	-	26627737	RPE1	viability after 9 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	-1.4185382631074963	[1807]	[147,293]	-7	hSpCas9	negative selection	1133882
39173596	39173619	19	+	26627737	RPE1	viability after 9 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-0.4990552702785558	[855]	[155,232]	-4	hSpCas9	negative selection	1133883
39175043	39175066	19	+	26627737	RPE1	viability after 9 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	0.21930559348222922	[1928]	[575,866]	1	hSpCas9	negative selection	1133884
39175374	39175397	19	+	26627737	RPE1	viability after 9 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	2.341530977274961	[49]	[60,102]	9	hSpCas9	negative selection	1133885
39176693	39176716	19	-	26627737	RPE1	viability after 9 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	1.7429533496730967	[166]	[143,214]	8	hSpCas9	negative selection	1133886
39169546	39169569	19	+	26627737	RPE1	viability after 12 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-1.1229975958893288	[2976]	[391,340]	-6	hSpCas9	negative selection	1216196
39173249	39173272	19	-	26627737	RPE1	viability after 12 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	-0.9605934267671641	[1807]	[286,209]	-6	hSpCas9	negative selection	1216197
39173596	39173619	19	+	26627737	RPE1	viability after 12 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-1.113939559060988	[855]	[97,114]	-6	hSpCas9	negative selection	1216198
39175043	39175066	19	+	26627737	RPE1	viability after 12 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	0.010458943278741195	[1928]	[386,664]	0	hSpCas9	negative selection	1216199
39175374	39175397	19	+	26627737	RPE1	viability after 12 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	2.1215626346987753	[49]	[56,59]	9	hSpCas9	negative selection	1216200
39176693	39176716	19	-	26627737	RPE1	viability after 12 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	1.243823134866107	[166]	[131,78]	7	hSpCas9	negative selection	1216201
39169546	39169569	19	+	26627737	RPE1	viability after 15 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-1.164321802904135	[2976]	[474,279]	-6	hSpCas9	negative selection	1298511
39173249	39173272	19	-	26627737	RPE1	viability after 15 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	-1.2184062725746556	[1807]	[174,262]	-6	hSpCas9	negative selection	1298512
39173596	39173619	19	+	26627737	RPE1	viability after 15 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-1.1499176578829169	[855]	[45,169]	-6	hSpCas9	negative selection	1298513
39175043	39175066	19	+	26627737	RPE1	viability after 15 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.27384144197230276	[1928]	[291,604]	-2	hSpCas9	negative selection	1298514
39175374	39175397	19	+	26627737	RPE1	viability after 15 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	1.5856699102017195	[49]	[16,66]	8	hSpCas9	negative selection	1298515
39176693	39176716	19	-	26627737	RPE1	viability after 15 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	1.5238024072124392	[166]	[172,99]	7	hSpCas9	negative selection	1298516
39169546	39169569	19	+	26627737	RPE1	viability after 18 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-1.1085574455980447	[2976]	[272,478]	-6	hSpCas9	negative selection	1380826
39173249	39173272	19	-	26627737	RPE1	viability after 18 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	-1.3063779222728984	[1807]	[190,203]	-7	hSpCas9	negative selection	1380827
39173596	39173619	19	+	26627737	RPE1	viability after 18 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-1.8839919843948763	[855]	[35,90]	-8	hSpCas9	negative selection	1380828
39175043	39175066	19	+	26627737	RPE1	viability after 18 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.16142728768881165	[1928]	[347,590]	-1	hSpCas9	negative selection	1380829
39175374	39175397	19	+	26627737	RPE1	viability after 18 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	1.7366011761648363	[49]	[43,45]	8	hSpCas9	negative selection	1380830
39176693	39176716	19	-	26627737	RPE1	viability after 18 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	1.1048190896064485	[166]	[123,67]	6	hSpCas9	negative selection	1380831
39169546	39169569	19	+	26627737	HeLa	viability after 8 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	0.06494764538484565	[1771]	[1171,756,586]	0	hSpCas9	negative selection	1463141
39173249	39173272	19	-	26627737	HeLa	viability after 8 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	1.3985219181671713	[282]	[355,361,266]	8	hSpCas9	negative selection	1463142
39173596	39173619	19	+	26627737	HeLa	viability after 8 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-0.06413626995526256	[235]	[64,177,47]	0	hSpCas9	negative selection	1463143
39175043	39175066	19	+	26627737	HeLa	viability after 8 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.4409777704214526	[1450]	[719,304,428]	-4	hSpCas9	negative selection	1463144
39175374	39175397	19	+	26627737	HeLa	viability after 8 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	-0.6268104015061287	[123]	[47,43,16]	-6	hSpCas9	negative selection	1463145
39176693	39176716	19	-	26627737	HeLa	viability after 8 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	0.07318882095972197	[350]	[140,209,128]	0	hSpCas9	negative selection	1463146
39169546	39169569	19	+	26627737	HeLa	viability after 12 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-0.09553170152108148	[1771]	[624,641,791]	-1	hSpCas9	negative selection	1545456
39173249	39173272	19	-	26627737	HeLa	viability after 12 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	1.0865403252208585	[282]	[187,279,271]	7	hSpCas9	negative selection	1545457
39173596	39173619	19	+	26627737	HeLa	viability after 12 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	0.3955229388211262	[235]	[195,107,84]	3	hSpCas9	negative selection	1545458
39175043	39175066	19	+	26627737	HeLa	viability after 12 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.5296975957189043	[1450]	[296,402,543]	-5	hSpCas9	negative selection	1545459
39175374	39175397	19	+	26627737	HeLa	viability after 12 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	-1.231242515828963	[123]	[21,16,26]	-8	hSpCas9	negative selection	1545460
39176693	39176716	19	-	26627737	HeLa	viability after 12 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	0.02231109087551289	[350]	[135,105,203]	0	hSpCas9	negative selection	1545461
39169546	39169569	19	+	26627737	HeLa	viability after 15 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-0.6085522652662321	[1771]	[412,402,614]	-5	hSpCas9	negative selection	1627771
39173249	39173272	19	-	26627737	HeLa	viability after 15 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	0.5153471603628619	[282]	[94,185,217]	4	hSpCas9	negative selection	1627772
39173596	39173619	19	+	26627737	HeLa	viability after 15 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	0.4330365003094792	[235]	[213,68,102]	3	hSpCas9	negative selection	1627773
39175043	39175066	19	+	26627737	HeLa	viability after 15 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.3588481433307562	[1450]	[202,723,457]	-3	hSpCas9	negative selection	1627774
39175374	39175397	19	+	26627737	HeLa	viability after 15 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	-0.07105655823686274	[123]	[90,23,26]	0	hSpCas9	negative selection	1627775
39176693	39176716	19	-	26627737	HeLa	viability after 15 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-0.4176347178946002	[350]	[42,35,253]	-4	hSpCas9	negative selection	1627776
39169546	39169569	19	+	26627737	HeLa	viability after 18 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-0.6027091408348171	[1771]	[286,325,614]	-5	hSpCas9	negative selection	1710086
39173249	39173272	19	-	26627737	HeLa	viability after 18 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	0.499259145943476	[282]	[60,152,217]	4	hSpCas9	negative selection	1710087
39173596	39173619	19	+	26627737	HeLa	viability after 18 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	0.4163922594325086	[235]	[143,52,102]	3	hSpCas9	negative selection	1710088
39175043	39175066	19	+	26627737	HeLa	viability after 18 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.34761882221922247	[1450]	[137,605,457]	-3	hSpCas9	negative selection	1710089
39175374	39175397	19	+	26627737	HeLa	viability after 18 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	-0.06729788156626304	[123]	[61,18,26]	0	hSpCas9	negative selection	1710090
39176693	39176716	19	-	26627737	HeLa	viability after 18 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-0.4238793446945803	[350]	[26,30,253]	-4	hSpCas9	negative selection	1710091
39169546	39169569	19	+	26627737	HCT116	viability after 6 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	1.254691947998677	[2102]	[1649,313]	6	hSpCas9	negative selection	1792401
39173249	39173272	19	-	26627737	HCT116	viability after 6 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	1.3586395998756893	[467]	[421,59]	7	hSpCas9	negative selection	1792402
39173596	39173619	19	+	26627737	HCT116	viability after 6 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	0.14494397705971263	[339]	[129,19]	0	hSpCas9	negative selection	1792403
39175043	39175066	19	+	26627737	HCT116	viability after 6 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	1.0714720372777207	[1199]	[574,297]	6	hSpCas9	negative selection	1792404
39175374	39175397	19	+	26627737	HCT116	viability after 6 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	-3.838534383011129	[90]	[0,0]	-9	hSpCas9	negative selection	1792405
39176693	39176716	19	-	26627737	HCT116	viability after 6 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	2.0528512388962143	[171]	[146,92]	8	hSpCas9	negative selection	1792406
39169546	39169569	19	+	26627737	HCT116	viability after 8 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	0.15827084991178575	[832]	[626,586,326]	1	hSpCas9	negative selection	1874716
39173249	39173272	19	-	26627737	HCT116	viability after 8 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	0.18979299018343992	[261]	[170,148,173]	2	hSpCas9	negative selection	1874717
39173596	39173619	19	+	26627737	HCT116	viability after 8 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-1.0465466812180915	[276]	[88,62,69]	-8	hSpCas9	negative selection	1874718
39175043	39175066	19	+	26627737	HCT116	viability after 8 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.46612804515964346	[1035]	[494,397,348]	-5	hSpCas9	negative selection	1874719
39175374	39175397	19	+	26627737	HCT116	viability after 8 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	0.2765765676510883	[26]	[12,24,15]	3	hSpCas9	negative selection	1874720
39176693	39176716	19	-	26627737	HCT116	viability after 8 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-0.4859250152014779	[272]	[135,99,86]	-5	hSpCas9	negative selection	1874721
39169546	39169569	19	+	26627737	HCT116	viability after 9 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-0.06827000020803631	[2102]	[467,588]	0	hSpCas9	negative selection	1957031
39173249	39173272	19	-	26627737	HCT116	viability after 9 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	0.8880049008827388	[467]	[161,285]	6	hSpCas9	negative selection	1957032
39173596	39173619	19	+	26627737	HCT116	viability after 9 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	0.053226434661094	[339]	[77,106]	0	hSpCas9	negative selection	1957033
39175043	39175066	19	+	26627737	HCT116	viability after 9 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	1.2576261957255548	[1199]	[368,1079]	8	hSpCas9	negative selection	1957034
39175374	39175397	19	+	26627737	HCT116	viability after 9 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	-4.602804828845228	[90]	[0,0]	-9	hSpCas9	negative selection	1957035
39176693	39176716	19	-	26627737	HCT116	viability after 9 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	1.7019005819766493	[171]	[216,95]	9	hSpCas9	negative selection	1957036
39169546	39169569	19	+	26627737	HCT116	viability after 12 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	0.1535205294621218	[832]	[357,648,468]	1	hSpCas9	negative selection	2039346
39173249	39173272	19	-	26627737	HCT116	viability after 12 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	-0.27400745707034035	[261]	[106,104,129]	-3	hSpCas9	negative selection	2039347
39173596	39173619	19	+	26627737	HCT116	viability after 12 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-0.5047699946979973	[276]	[112,107,85]	-5	hSpCas9	negative selection	2039348
39175043	39175066	19	+	26627737	HCT116	viability after 12 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.1834630578204519	[1035]	[405,324,709]	-2	hSpCas9	negative selection	2039349
39175374	39175397	19	+	26627737	HCT116	viability after 12 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	0.8095902441764471	[26]	[10,31,32]	7	hSpCas9	negative selection	2039350
39176693	39176716	19	-	26627737	HCT116	viability after 12 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-0.38781200846873787	[272]	[143,70,109]	-4	hSpCas9	negative selection	2039351
39169546	39169569	19	+	26627737	HCT116	viability after 15 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	0.05700600357201657	[832]	[425,619,438]	0	hSpCas9	negative selection	2121661
39173249	39173272	19	-	26627737	HCT116	viability after 15 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	0.08027941150043949	[261]	[103,163,201]	0	hSpCas9	negative selection	2121662
39173596	39173619	19	+	26627737	HCT116	viability after 15 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-1.392406853410157	[276]	[94,31,58]	-8	hSpCas9	negative selection	2121663
39175043	39175066	19	+	26627737	HCT116	viability after 15 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.420185574638261	[1035]	[448,569,316]	-4	hSpCas9	negative selection	2121664
39175374	39175397	19	+	26627737	HCT116	viability after 15 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	0.6791507703725217	[26]	[36,16,21]	6	hSpCas9	negative selection	2121665
39176693	39176716	19	-	26627737	HCT116	viability after 15 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-0.3418199267588743	[272]	[260,99,27]	-4	hSpCas9	negative selection	2121666
39169546	39169569	19	+	26627737	HCT116	viability after 18 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	0.14698107858743725	[832]	[350,687,274]	1	hSpCas9	negative selection	2203976
39173249	39173272	19	-	26627737	HCT116	viability after 18 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	-0.09430073165634137	[261]	[159,66,132]	-1	hSpCas9	negative selection	2203977
39173596	39173619	19	+	26627737	HCT116	viability after 18 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-1.1626436223346899	[276]	[85,52,39]	-8	hSpCas9	negative selection	2203978
39175043	39175066	19	+	26627737	HCT116	viability after 18 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.5001302536529222	[1035]	[431,333,294]	-4	hSpCas9	negative selection	2203979
39175374	39175397	19	+	26627737	HCT116	viability after 18 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	0.6048366269874776	[26]	[13,26,17]	5	hSpCas9	negative selection	2203980
39176693	39176716	19	-	26627737	HCT116	viability after 18 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-1.333980191306629	[272]	[50,61,42]	-8	hSpCas9	negative selection	2203981
39169546	39169569	19	+	24336569	HL60	viability	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	1.3739387663233438	[325]	[1787]	8	hSpCas9	negative selection	2282522
39169552	39169575	19	-	24336569	HL60	viability	CTTCTTCCTCTTCCCAAACATGG	PAK4	ENSG00000130669	2.088460900813416	[101]	[917]	9	hSpCas9	negative selection	2282523
39169559	39169582	19	+	24336569	HL60	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-0.4232725400639086	[1433]	[2262]	-4	hSpCas9	negative selection	2282524
39169588	39169611	19	-	24336569	HL60	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	0.522062004993636	[591]	[1798]	4	hSpCas9	negative selection	2282525
39169593	39169616	19	-	24336569	HL60	viability	ACGCGGTGCTCGAAGTTGGACGG	PAK4	ENSG00000130669	-0.6920078965130974	[696]	[912]	-6	hSpCas9	negative selection	2282526
39169601	39169624	19	+	24336569	HL60	viability	CTTCGAGCACCGCGTGCACACGG	PAK4	ENSG00000130669	0.8245013939277961	[415]	[1558]	6	hSpCas9	negative selection	2282527
39169610	39169633	19	-	24336569	HL60	viability	GGTCGAAGCCCGTGTGCACGCGG	PAK4	ENSG00000130669	-0.12578102304584904	[875]	[1698]	-1	hSpCas9	negative selection	2282528
39169631	39169654	19	-	24336569	HL60	viability	CCGTGAACTTCTGCTCGTGCTGG	PAK4	ENSG00000130669	1.0812499859183184	[311]	[1396]	8	hSpCas9	negative selection	2282529
39169660	39169683	19	-	24336569	HL60	viability	GATCAGGCTCTGCCACTGGCGGG	PAK4	ENSG00000130669	0.18031085943229908	[381]	[915]	1	hSpCas9	negative selection	2282530
39169670	39169693	19	+	24336569	HL60	viability	GCAGAGCCTGATCGAGGAGTCGG	PAK4	ENSG00000130669	0.8695727477295976	[928]	[3591]	7	hSpCas9	negative selection	2282531
39169546	39169569	19	+	24336569	KBM7	viability	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	0.6536911602180697	[470]	[2020]	6	hSpCas9	negative selection	2349699
39169552	39169575	19	-	24336569	KBM7	viability	CTTCTTCCTCTTCCCAAACATGG	PAK4	ENSG00000130669	1.6435686915093128	[137]	[1175]	9	hSpCas9	negative selection	2349700
39169559	39169582	19	+	24336569	KBM7	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-1.5873039602154957	[1039]	[943]	-8	hSpCas9	negative selection	2349701
39169588	39169611	19	-	24336569	KBM7	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	0.34639669570752174	[649]	[2253]	3	hSpCas9	negative selection	2349702
39169593	39169616	19	-	24336569	KBM7	viability	ACGCGGTGCTCGAAGTTGGACGG	PAK4	ENSG00000130669	0.1177685435140017	[468]	[1387]	1	hSpCas9	negative selection	2349703
39169601	39169624	19	+	24336569	KBM7	viability	CTTCGAGCACCGCGTGCACACGG	PAK4	ENSG00000130669	0.6656987901999213	[504]	[2184]	6	hSpCas9	negative selection	2349704
39169610	39169633	19	-	24336569	KBM7	viability	GGTCGAAGCCCGTGTGCACGCGG	PAK4	ENSG00000130669	-0.3416364867985433	[688]	[1482]	-3	hSpCas9	negative selection	2349705
39169631	39169654	19	-	24336569	KBM7	viability	CCGTGAACTTCTGCTCGTGCTGG	PAK4	ENSG00000130669	0.3841960909986444	[317]	[1131]	3	hSpCas9	negative selection	2349706
39169660	39169683	19	-	24336569	KBM7	viability	GATCAGGCTCTGCCACTGGCGGG	PAK4	ENSG00000130669	1.7883090672717883	[246]	[2326]	9	hSpCas9	negative selection	2349707
39169670	39169693	19	+	24336569	KBM7	viability	GCAGAGCCTGATCGAGGAGTCGG	PAK4	ENSG00000130669	0.11533404491064836	[966]	[2856]	1	hSpCas9	negative selection	2349708
39169634	39169657	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCACGAGCAGAAGTTCACGGGG	PAK4	ENSG00000130669	-0.14779055262490812	[3,3]	[3,0]	-2	hSpCas9	positive selection	3009476
39169728	39169751	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATCACCTCCATCCAGCCCGGGG	PAK4	ENSG00000130669	0.1944426808655548	[2,2]	[2,2]	4	hSpCas9	positive selection	3009477
39173686	39173709	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTGGGGTCCCAGCACTCCAGGG	PAK4	ENSG00000130669	-0.3130512420389986	[2,2]	[1,1]	-4	hSpCas9	positive selection	3009478
39173955	39173978	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGCAGGTCCATCTTCTTGACGG	PAK4	ENSG00000130669	-0.36464071307090085	[3,2]	[1,1]	-5	hSpCas9	positive selection	3009479
39169634	39169657	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCACGAGCAGAAGTTCACGGGG	PAK4	ENSG00000130669	0.23820027124648435	[3,3]	[2,2]	4	hSpCas9	positive selection	3077334
39169728	39169751	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATCACCTCCATCCAGCCCGGGG	PAK4	ENSG00000130669	-0.6462385176972278	[2,2]	[1,0]	-8	hSpCas9	positive selection	3077335
39173686	39173709	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTGGGGTCCCAGCACTCCAGGG	PAK4	ENSG00000130669	-0.6954040079982728	[2,2]	[1,0]	-8	hSpCas9	positive selection	3077336
39173955	39173978	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGCAGGTCCATCTTCTTGACGG	PAK4	ENSG00000130669	0.22706185605333823	[3,3]	[2,2]	4	hSpCas9	positive selection	3077337
39173235	39173258		-	24336571	A375	resistance to PLX after 7 days	CGGAGAGGGGGCGTTTGTCCCGG	PAK4	ENSG00000130669	0.09555852070011905	[3,4]	[4,4]	3	hSpCas9	positive selection	3133815
39175312	39175335		+	24336571	A375	resistance to PLX after 7 days	GATGAACGAGGAGCAGATCGCGG	PAK4	ENSG00000130669	-0.2548789362607652	[14,10]	[11,9]	-7	hSpCas9	positive selection	3133816
39173989	39174012		+	24336571	A375	resistance to PLX after 7 days	GCGCGAGCTGCTCTTCAACGAGG	PAK4	ENSG00000130669	0.14110809703865432	[13,11]	[13,13]	4	hSpCas9	positive selection	3133817
39173321	39173344		+	24336571	A375	resistance to PLX after 7 days	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.17829229698397192	[6,9]	[9,9]	5	hSpCas9	positive selection	3133818
39173904	39173927		-	24336571	A375	resistance to PLX after 7 days	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.3089978133024728	[4,4]	[5,6]	8	hSpCas9	positive selection	3133819
39173235	39173258		-	24336571	A375	resistance to PLX after 14 days	CGGAGAGGGGGCGTTTGTCCCGG	PAK4	ENSG00000130669	-0.030840422308556326	[3,5]	[1,1]	0	hSpCas9	positive selection	3191608
39175312	39175335		+	24336571	A375	resistance to PLX after 14 days	GATGAACGAGGAGCAGATCGCGG	PAK4	ENSG00000130669	-0.5971069490795781	[13,10]	[3,3]	-7	hSpCas9	positive selection	3191609
39173989	39174012		+	24336571	A375	resistance to PLX after 14 days	GCGCGAGCTGCTCTTCAACGAGG	PAK4	ENSG00000130669	1.0112010763721555	[11,15]	[10,14]	7	hSpCas9	positive selection	3191610
39173321	39173344		+	24336571	A375	resistance to PLX after 14 days	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-0.1251789044265863	[7,9]	[2,3]	-1	hSpCas9	positive selection	3191611
39173904	39173927		-	24336571	A375	resistance to PLX after 14 days	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.2682406822759871	[8,7]	[2,2]	-3	hSpCas9	positive selection	3191612
39173235	39173258		-	24336571	A375	viability after 7 days	CGGAGAGGGGGCGTTTGTCCCGG	PAK4	ENSG00000130669	-0.2841129138445744	[5]	[3,4]	-4	hSpCas9	negative selection	3249401
39175312	39175335		+	24336571	A375	viability after 7 days	GATGAACGAGGAGCAGATCGCGG	PAK4	ENSG00000130669	-0.15031455575587166	[14]	[14,10]	-2	hSpCas9	negative selection	3249402
39173989	39174012		+	24336571	A375	viability after 7 days	GCGCGAGCTGCTCTTCAACGAGG	PAK4	ENSG00000130669	0.2299278610686316	[11]	[13,11]	3	hSpCas9	negative selection	3249403
39173321	39173344		+	24336571	A375	viability after 7 days	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.09667745364229097	[8]	[6,9]	1	hSpCas9	negative selection	3249404
39173904	39173927		-	24336571	A375	viability after 7 days	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.12017502929307944	[4]	[4,4]	1	hSpCas9	negative selection	3249405
39173235	39173258		-	24336571	A375	viability after 14 days	CGGAGAGGGGGCGTTTGTCCCGG	PAK4	ENSG00000130669	-0.16818662708370424	[5]	[3,5]	-2	hSpCas9	negative selection	3307194
39175312	39175335		+	24336571	A375	viability after 14 days	GATGAACGAGGAGCAGATCGCGG	PAK4	ENSG00000130669	-0.19643904317828362	[14]	[13,10]	-2	hSpCas9	negative selection	3307195
39173989	39174012		+	24336571	A375	viability after 14 days	GCGCGAGCTGCTCTTCAACGAGG	PAK4	ENSG00000130669	0.32944442830890003	[11]	[11,15]	4	hSpCas9	negative selection	3307196
39173321	39173344		+	24336571	A375	viability after 14 days	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.12478723856122609	[8]	[7,9]	1	hSpCas9	negative selection	3307197
39173904	39173927		-	24336571	A375	viability after 14 days	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.7467393587541564	[4]	[8,7]	8	hSpCas9	negative selection	3307198
39172919	39172942	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.8033697202417188	[266,266]	[0,0]	-5	hSpCas9	positive selection	3384521
39174923	39174946	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	0.7574803243626298	[180,180]	[1,1]	3	hSpCas9	positive selection	3384522
39174951	39174974	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.274055249070477	[184,184]	[0,0]	-2	hSpCas9	positive selection	3384523
39169633	39169656	19	+	26780180	HT29	viability (Avana library 4 designs)	AGCACGAGCAGAAGTTCACGGGG	PAK4	ENSG00000130669	1.94084398669586	[]	[]	7	hSpCas9	negative selection	3447513
39169727	39169750	19	+	26780180	HT29	viability (Avana library 4 designs)	CATCACCTCCATCCAGCCCGGGG	PAK4	ENSG00000130669	1.48266407604762	[]	[]	6	hSpCas9	negative selection	3447514
39173686	39173709	19	-	26780180	HT29	viability (Avana library 4 designs)	CGTGGGGTCCCAGCACTCCAGGG	PAK4	ENSG00000130669	1.95435874555795	[]	[]	7	hSpCas9	negative selection	3447515
39173955	39173978	19	-	26780180	HT29	viability (Avana library 4 designs)	GCGCAGGTCCATCTTCTTGACGG	PAK4	ENSG00000130669	1.27060093176216	[]	[]	5	hSpCas9	negative selection	3447516
39173686	39173709	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGTGGGGTCCCAGCACTCCAGGG	PAK4	ENSG00000130669	3.9139067042225	[]	[]	6	hSpCas9	negative selection	3541355
39169633	39169656	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGCACGAGCAGAAGTTCACGGGG	PAK4	ENSG00000130669	-4.19896158891071	[]	[]	-5	hSpCas9	negative selection	3541356
39173955	39173978	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCAGGTCCATCTTCTTGACGG	PAK4	ENSG00000130669	-0.776937063769975	[]	[]	-1	hSpCas9	negative selection	3541357
39169727	39169750	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATCACCTCCATCCAGCCCGGGG	PAK4	ENSG00000130669	0.886794113522409	[]	[]	1	hSpCas9	negative selection	3541358
39173860	39173883	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTTGTCCAGGTAGGAGCGGGGG	PAK4	ENSG00000130669	0.550278654529848	[]	[]	0	hSpCas9	negative selection	3541359
39173989	39174012	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCGAGCTGCTCTTCAACGAGG	PAK4	ENSG00000130669	4.09183883188666	[]	[]	6	hSpCas9	negative selection	3541360
39173686	39173709	19	-	26780180	A375	viability (Avana lentiGuide)	CGTGGGGTCCCAGCACTCCAGGG	PAK4	ENSG00000130669	2.77176322497292	[]	[]	3	hSpCas9	negative selection	3650014
39169633	39169656	19	+	26780180	A375	viability (Avana lentiGuide)	AGCACGAGCAGAAGTTCACGGGG	PAK4	ENSG00000130669	5.39478921868192	[]	[]	5	hSpCas9	negative selection	3650015
39173955	39173978	19	-	26780180	A375	viability (Avana lentiGuide)	GCGCAGGTCCATCTTCTTGACGG	PAK4	ENSG00000130669	-3.88319314071897	[]	[]	-6	hSpCas9	negative selection	3650016
39169727	39169750	19	+	26780180	A375	viability (Avana lentiGuide)	CATCACCTCCATCCAGCCCGGGG	PAK4	ENSG00000130669	10.668281743309	[]	[]	7	hSpCas9	negative selection	3650017
39173860	39173883	19	-	26780180	A375	viability (Avana lentiGuide)	AGTTGTCCAGGTAGGAGCGGGGG	PAK4	ENSG00000130669	13.5731328588318	[]	[]	7	hSpCas9	negative selection	3650018
39173989	39174012	19	+	26780180	A375	viability (Avana lentiGuide)	GCGCGAGCTGCTCTTCAACGAGG	PAK4	ENSG00000130669	2.11004924886836	[]	[]	2	hSpCas9	negative selection	3650019
39173686	39173709	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTGGGGTCCCAGCACTCCAGGG	PAK4	ENSG00000130669	0.32539356924230234	[5]	[6,6]	8	hSpCas9	positive selection	3758673
39169633	39169656	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCACGAGCAGAAGTTCACGGGG	PAK4	ENSG00000130669	0.00499958720589877	[4]	[4,4]	0	hSpCas9	positive selection	3758674
39173955	39173978	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCAGGTCCATCTTCTTGACGG	PAK4	ENSG00000130669	0.045691286809091625	[3]	[3,3]	1	hSpCas9	positive selection	3758675
39169727	39169750	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCACCTCCATCCAGCCCGGGG	PAK4	ENSG00000130669	0.260843778079269	[4]	[5,4]	7	hSpCas9	positive selection	3758676
39173860	39173883	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTTGTCCAGGTAGGAGCGGGGG	PAK4	ENSG00000130669	0.27559502905732647	[3]	[4,4]	7	hSpCas9	positive selection	3758677
39173989	39174012	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCGAGCTGCTCTTCAACGAGG	PAK4	ENSG00000130669	0.16953736516709278	[4]	[5,3]	4	hSpCas9	positive selection	3758678
39173686	39173709	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTGGGGTCCCAGCACTCCAGGG	PAK4	ENSG00000130669	-0.21012813034398473	[5]	[3,3]	-3	hSpCas9	positive selection	3867280
39169633	39169656	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCACGAGCAGAAGTTCACGGGG	PAK4	ENSG00000130669	-1.3907603135438222	[5]	[0,1]	-9	hSpCas9	positive selection	3867281
39173955	39173978	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCAGGTCCATCTTCTTGACGG	PAK4	ENSG00000130669	0.20405576830991098	[4]	[2,5]	5	hSpCas9	positive selection	3867282
39169727	39169750	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCACCTCCATCCAGCCCGGGG	PAK4	ENSG00000130669	-0.7145072306731381	[4]	[1,2]	-7	hSpCas9	positive selection	3867283
39173860	39173883	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTTGTCCAGGTAGGAGCGGGGG	PAK4	ENSG00000130669	0.19614451753194437	[4]	[5,3]	5	hSpCas9	positive selection	3867284
39173989	39174012	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCGAGCTGCTCTTCAACGAGG	PAK4	ENSG00000130669	0.2712625895760522	[5]	[5,6]	7	hSpCas9	positive selection	3867285
39172919	39172942	19	-	26780180	A375	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.997809213184134	[]	[]	4	hSpCas9	negative selection	3978177
39174923	39174946	19	+	26780180	A375	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	1.39574472811419	[]	[]	7	hSpCas9	negative selection	3978178
39173321	39173344	19	+	26780180	A375	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.920143829275583	[]	[]	4	hSpCas9	negative selection	3978179
39173904	39173927	19	-	26780180	A375	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.793572768716325	[]	[]	3	hSpCas9	negative selection	3978180
39174951	39174974	19	-	26780180	A375	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	2.48924051973358	[]	[]	9	hSpCas9	negative selection	3978181
39173798	39173821	19	-	26780180	A375	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	0.917630444332197	[]	[]	4	hSpCas9	negative selection	3978182
39172919	39172942	19	-	26780180	HT29	viability (GeCKOv2 library)	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.834925025409988	[]	[]	3	hSpCas9	negative selection	4086143
39174923	39174946	19	+	26780180	HT29	viability (GeCKOv2 library)	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	0.937208844213069	[]	[]	4	hSpCas9	negative selection	4086144
39173321	39173344	19	+	26780180	HT29	viability (GeCKOv2 library)	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.366195887778091	[]	[]	1	hSpCas9	negative selection	4086145
39173904	39173927	19	-	26780180	HT29	viability (GeCKOv2 library)	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	1.10564784396496	[]	[]	5	hSpCas9	negative selection	4086146
39174951	39174974	19	-	26780180	HT29	viability (GeCKOv2 library)	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	2.29165060682994	[]	[]	9	hSpCas9	negative selection	4086147
39173798	39173821	19	-	26780180	HT29	viability (GeCKOv2 library)	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	0.453302490308014	[]	[]	1	hSpCas9	negative selection	4086148
39173235	39173258	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGAGAGGGGGCGTTTGTCCCGG	PAK4	ENSG00000130669	-0.560282055843706	[1]	[0,0]	-9	hSpCas9	positive selection	4158662
39175312	39175335	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATGAACGAGGAGCAGATCGCGG	PAK4	ENSG00000130669	-0.35974787613244724	[3]	[1,1]	-7	hSpCas9	positive selection	4158663
39173989	39174012	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCGAGCTGCTCTTCAACGAGG	PAK4	ENSG00000130669	0.2854948046856574	[3]	[2,3]	7	hSpCas9	positive selection	4158664
39173321	39173344	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-0.039284833207481745	[3]	[2,1]	-1	hSpCas9	positive selection	4158665
39173904	39173927	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.11391366396943614	[2]	[2,1]	3	hSpCas9	positive selection	4158666
39173235	39173258	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGAGAGGGGGCGTTTGTCCCGG	PAK4	ENSG00000130669	0.23828061448768778	[1]	[1,0,0,0]	1	hSpCas9	positive selection	4222684
39175312	39175335	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATGAACGAGGAGCAGATCGCGG	PAK4	ENSG00000130669	-0.05560083771714369	[5]	[2,3,3,0]	-1	hSpCas9	positive selection	4222685
39173989	39174012	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCGAGCTGCTCTTCAACGAGG	PAK4	ENSG00000130669	0.6822004498897222	[1]	[1,0,3,0]	4	hSpCas9	positive selection	4222686
39173321	39173344	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	1.255639240395453	[1]	[2,0,4,0]	9	hSpCas9	positive selection	4222687
39173904	39173927	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.931541475110854	[1]	[0,3,0,0]	6	hSpCas9	positive selection	4222688
39173904	39173927	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.25624534752514927	[1]	[1,1]	5	hSpCas9	positive selection	4288698
39173321	39173344	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.043647404568471895	[2]	[2,1]	0	hSpCas9	positive selection	4288699
39173798	39173821	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.24451388955862186	[1]	[1,0]	-5	hSpCas9	positive selection	4288700
39172919	39172942	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.12860063651635045	[3]	[3,2]	2	hSpCas9	positive selection	4352951
39174923	39174946	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.35059248875788723	[3]	[3,0]	-6	hSpCas9	positive selection	4352952
39174951	39174974	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.19224624989362438	[3]	[2,1]	-4	hSpCas9	positive selection	4352953
39169676	39169698	19	-	27760321	OCIAML3	viability	GCGAGCCGACTCCTCGATCAGG	PAK4	ENSG00000130669	0.24300461370446513	[736,606]	[533,729]	3	hSpCas9	negative selection	4425409
39173584	39173606	19	+	27760321	OCIAML3	viability	TCATGACGTGGCCCCTAACGGG	PAK4	ENSG00000130669	0.3681127579913887	[506,391]	[380,540]	4	hSpCas9	negative selection	4425410
39173598	39173620	19	+	27760321	OCIAML3	viability	CTAACGGGCCATCAGCGGGGGG	PAK4	ENSG00000130669	0.09312792111762724	[821,588]	[463,736]	1	hSpCas9	negative selection	4425411
39173880	39173902	19	+	27760321	OCIAML3	viability	ACTTCATCAAGATTGGCGAGGG	PAK4	ENSG00000130669	0.1698817393397679	[705,646]	[581,611]	2	hSpCas9	negative selection	4425412
39174925	39174947	19	+	27760321	OCIAML3	viability	GCACAGGTGGTAATCATGAGGG	PAK4	ENSG00000130669	0.641023424006828	[294,192]	[279,310]	7	hSpCas9	negative selection	4425413
39169676	39169698	19	-	27760321	OCIAML2	viability	GCGAGCCGACTCCTCGATCAGG	PAK4	ENSG00000130669	-0.09191760013258032	[736,606]	[489,530]	-1	hSpCas9	negative selection	4508872
39173584	39173606	19	+	27760321	OCIAML2	viability	TCATGACGTGGCCCCTAACGGG	PAK4	ENSG00000130669	0.43090828485314703	[506,391]	[389,613]	6	hSpCas9	negative selection	4508873
39173598	39173620	19	+	27760321	OCIAML2	viability	CTAACGGGCCATCAGCGGGGGG	PAK4	ENSG00000130669	0.5545725069102168	[821,588]	[716,977]	7	hSpCas9	negative selection	4508874
39173880	39173902	19	+	27760321	OCIAML2	viability	ACTTCATCAAGATTGGCGAGGG	PAK4	ENSG00000130669	0.5234209535817135	[705,646]	[709,886]	7	hSpCas9	negative selection	4508875
39174925	39174947	19	+	27760321	OCIAML2	viability	GCACAGGTGGTAATCATGAGGG	PAK4	ENSG00000130669	0.1263803832475785	[294,192]	[164,274]	1	hSpCas9	negative selection	4508876
39169676	39169698	19	-	27760321	MV411	viability	GCGAGCCGACTCCTCGATCAGG	PAK4	ENSG00000130669	-0.7306686085210781	[736,606]	[14,642]	-5	hSpCas9	negative selection	4592335
39173584	39173606	19	+	27760321	MV411	viability	TCATGACGTGGCCCCTAACGGG	PAK4	ENSG00000130669	1.0468730119174288	[506,391]	[631,572]	7	hSpCas9	negative selection	4592336
39173598	39173620	19	+	27760321	MV411	viability	CTAACGGGCCATCAGCGGGGGG	PAK4	ENSG00000130669	0.42108518272944795	[821,588]	[799,341]	3	hSpCas9	negative selection	4592337
39173880	39173902	19	+	27760321	MV411	viability	ACTTCATCAAGATTGGCGAGGG	PAK4	ENSG00000130669	0.2798620028286465	[705,646]	[580,482]	2	hSpCas9	negative selection	4592338
39174925	39174947	19	+	27760321	MV411	viability	GCACAGGTGGTAATCATGAGGG	PAK4	ENSG00000130669	1.5588988459496589	[294,192]	[729,73]	9	hSpCas9	negative selection	4592339
39169676	39169698	19	-	27760321	HL60	viability	GCGAGCCGACTCCTCGATCAGG	PAK4	ENSG00000130669	-0.2311194240552955	[736,606]	[531,394]	-3	hSpCas9	negative selection	4675798
39173584	39173606	19	+	27760321	HL60	viability	TCATGACGTGGCCCCTAACGGG	PAK4	ENSG00000130669	-0.2877363371741492	[506,391]	[252,346]	-3	hSpCas9	negative selection	4675799
39173598	39173620	19	+	27760321	HL60	viability	CTAACGGGCCATCAGCGGGGGG	PAK4	ENSG00000130669	0.6585519801608692	[821,588]	[762,1045]	7	hSpCas9	negative selection	4675800
39173880	39173902	19	+	27760321	HL60	viability	ACTTCATCAAGATTGGCGAGGG	PAK4	ENSG00000130669	-0.1675771770031083	[705,646]	[470,513]	-2	hSpCas9	negative selection	4675801
39174925	39174947	19	+	27760321	HL60	viability	GCACAGGTGGTAATCATGAGGG	PAK4	ENSG00000130669	0.06763903682444372	[294,192]	[188,223]	0	hSpCas9	negative selection	4675802
39169676	39169698	19	-	27760321	HT1080	viability	GCGAGCCGACTCCTCGATCAGG	PAK4	ENSG00000130669	-1.092718586586075	[606,473]	[57,147]	-4	hSpCas9	negative selection	4759261
39173584	39173606	19	+	27760321	HT1080	viability	TCATGACGTGGCCCCTAACGGG	PAK4	ENSG00000130669	-1.1091864304863406	[391,305]	[94,30]	-4	hSpCas9	negative selection	4759262
39173598	39173620	19	+	27760321	HT1080	viability	CTAACGGGCCATCAGCGGGGGG	PAK4	ENSG00000130669	-0.9097302192000285	[588,459]	[136,82]	-4	hSpCas9	negative selection	4759263
39173880	39173902	19	+	27760321	HT1080	viability	ACTTCATCAAGATTGGCGAGGG	PAK4	ENSG00000130669	-2.2789951818314194	[646,504]	[10,86]	-6	hSpCas9	negative selection	4759264
39174925	39174947	19	+	27760321	HT1080	viability	GCACAGGTGGTAATCATGAGGG	PAK4	ENSG00000130669	1.6698169491691623	[192,150]	[355,66]	8	hSpCas9	negative selection	4759265
39169676	39169698	19	-	27760321	HT29	viability after 7 days	GCGAGCCGACTCCTCGATCAGG	PAK4	ENSG00000130669	0.07589808525448039	[606,473]	[1013,726,502]	1	hSpCas9	negative selection	4842724
39173584	39173606	19	+	27760321	HT29	viability after 7 days	TCATGACGTGGCCCCTAACGGG	PAK4	ENSG00000130669	0.13674641833835977	[391,305]	[645,391,463]	2	hSpCas9	negative selection	4842725
39173598	39173620	19	+	27760321	HT29	viability after 7 days	CTAACGGGCCATCAGCGGGGGG	PAK4	ENSG00000130669	0.5112770765929273	[588,459]	[923,1025,927]	7	hSpCas9	negative selection	4842726
39173880	39173902	19	+	27760321	HT29	viability after 7 days	ACTTCATCAAGATTGGCGAGGG	PAK4	ENSG00000130669	-0.012906698403287398	[646,504]	[853,566,794]	0	hSpCas9	negative selection	4842727
39174925	39174947	19	+	27760321	HT29	viability after 7 days	GCACAGGTGGTAATCATGAGGG	PAK4	ENSG00000130669	0.5938259209706385	[192,150]	[174,459,342]	8	hSpCas9	negative selection	4842728
39169676	39169698	19	-	27760321	HT29	viability after 25 days	GCGAGCCGACTCCTCGATCAGG	PAK4	ENSG00000130669	-0.352650367520599	[606,473]	[638,384,408]	-4	hSpCas9	negative selection	4926187
39173584	39173606	19	+	27760321	HT29	viability after 25 days	TCATGACGTGGCCCCTAACGGG	PAK4	ENSG00000130669	-0.06560863016312819	[391,305]	[273,429,452]	0	hSpCas9	negative selection	4926188
39173598	39173620	19	+	27760321	HT29	viability after 25 days	CTAACGGGCCATCAGCGGGGGG	PAK4	ENSG00000130669	0.510851870791029	[588,459]	[796,1022,731]	5	hSpCas9	negative selection	4926189
39173880	39173902	19	+	27760321	HT29	viability after 25 days	ACTTCATCAAGATTGGCGAGGG	PAK4	ENSG00000130669	-0.19428596652718472	[646,504]	[749,475,477]	-2	hSpCas9	negative selection	4926190
39174925	39174947	19	+	27760321	HT29	viability after 25 days	GCACAGGTGGTAATCATGAGGG	PAK4	ENSG00000130669	0.0002840612202419379	[192,150]	[144,249,197]	0	hSpCas9	negative selection	4926191
39169676	39169698	19	-	27760321	HT29	viability after 22 days	GCGAGCCGACTCCTCGATCAGG	PAK4	ENSG00000130669	-0.10886152535266613	[606,473]	[609,495,631]	-1	hSpCas9	negative selection	5009650
39173584	39173606	19	+	27760321	HT29	viability after 22 days	TCATGACGTGGCCCCTAACGGG	PAK4	ENSG00000130669	-0.3196027632404308	[391,305]	[399,222,344]	-3	hSpCas9	negative selection	5009651
39173598	39173620	19	+	27760321	HT29	viability after 22 days	CTAACGGGCCATCAGCGGGGGG	PAK4	ENSG00000130669	0.1895060937746903	[588,459]	[609,842,622]	2	hSpCas9	negative selection	5009652
39173880	39173902	19	+	27760321	HT29	viability after 22 days	ACTTCATCAAGATTGGCGAGGG	PAK4	ENSG00000130669	-0.5014926584286593	[646,504]	[457,421,531]	-4	hSpCas9	negative selection	5009653
39174925	39174947	19	+	27760321	HT29	viability after 22 days	GCACAGGTGGTAATCATGAGGG	PAK4	ENSG00000130669	-0.248116951407378	[192,150]	[89,291,121]	-3	hSpCas9	negative selection	5009654
39169676	39169698	19	-	27760321	HT29	viability after 19 days	GCGAGCCGACTCCTCGATCAGG	PAK4	ENSG00000130669	-0.07671093472106416	[606,473]	[850,674,271]	0	hSpCas9	negative selection	5093113
39173584	39173606	19	+	27760321	HT29	viability after 19 days	TCATGACGTGGCCCCTAACGGG	PAK4	ENSG00000130669	-0.2816583326612237	[391,305]	[265,294,413]	-3	hSpCas9	negative selection	5093114
39173598	39173620	19	+	27760321	HT29	viability after 19 days	CTAACGGGCCATCAGCGGGGGG	PAK4	ENSG00000130669	0.6852212073785424	[588,459]	[772,946,1145]	7	hSpCas9	negative selection	5093115
39173880	39173902	19	+	27760321	HT29	viability after 19 days	ACTTCATCAAGATTGGCGAGGG	PAK4	ENSG00000130669	-0.4484102350645829	[646,504]	[755,355,368]	-4	hSpCas9	negative selection	5093116
39174925	39174947	19	+	27760321	HT29	viability after 19 days	GCACAGGTGGTAATCATGAGGG	PAK4	ENSG00000130669	0.5327843201906137	[192,150]	[226,210,404]	5	hSpCas9	negative selection	5093117
39169676	39169698	19	-	27760321	HT29	viability after 16 days	GCGAGCCGACTCCTCGATCAGG	PAK4	ENSG00000130669	-0.2570803230437462	[606,473]	[681,376,478]	-3	hSpCas9	negative selection	5176576
39173584	39173606	19	+	27760321	HT29	viability after 16 days	TCATGACGTGGCCCCTAACGGG	PAK4	ENSG00000130669	0.13859133661498219	[391,305]	[435,315,540]	1	hSpCas9	negative selection	5176577
39173598	39173620	19	+	27760321	HT29	viability after 16 days	CTAACGGGCCATCAGCGGGGGG	PAK4	ENSG00000130669	0.5949238066355929	[588,459]	[742,1168,725]	7	hSpCas9	negative selection	5176578
39173880	39173902	19	+	27760321	HT29	viability after 16 days	ACTTCATCAAGATTGGCGAGGG	PAK4	ENSG00000130669	-0.6278344601948534	[646,504]	[406,229,617]	-5	hSpCas9	negative selection	5176579
39174925	39174947	19	+	27760321	HT29	viability after 16 days	GCACAGGTGGTAATCATGAGGG	PAK4	ENSG00000130669	0.17175409008996234	[192,150]	[227,155,268]	1	hSpCas9	negative selection	5176580
39169676	39169698	19	-	27760321	HT29	viability after 13 days	GCGAGCCGACTCCTCGATCAGG	PAK4	ENSG00000130669	-0.022355681792809334	[606,473]	[621,763,474]	0	hSpCas9	negative selection	5260039
39173584	39173606	19	+	27760321	HT29	viability after 13 days	TCATGACGTGGCCCCTAACGGG	PAK4	ENSG00000130669	0.3069110969116939	[391,305]	[722,414,371]	4	hSpCas9	negative selection	5260040
39173598	39173620	19	+	27760321	HT29	viability after 13 days	CTAACGGGCCATCAGCGGGGGG	PAK4	ENSG00000130669	0.47015773290255924	[588,459]	[820,835,869]	6	hSpCas9	negative selection	5260041
39173880	39173902	19	+	27760321	HT29	viability after 13 days	ACTTCATCAAGATTGGCGAGGG	PAK4	ENSG00000130669	-0.16364558487268754	[646,504]	[674,544,570]	-2	hSpCas9	negative selection	5260042
39174925	39174947	19	+	27760321	HT29	viability after 13 days	GCACAGGTGGTAATCATGAGGG	PAK4	ENSG00000130669	0.26117685361391296	[192,150]	[137,174,394]	3	hSpCas9	negative selection	5260043
39169676	39169698	19	-	27760321	HT29	viability after 10 days	GCGAGCCGACTCCTCGATCAGG	PAK4	ENSG00000130669	-0.10069317620633661	[606,473]	[524,715,648]	-1	hSpCas9	negative selection	5343502
39173584	39173606	19	+	27760321	HT29	viability after 10 days	TCATGACGTGGCCCCTAACGGG	PAK4	ENSG00000130669	0.6964309974117608	[391,305]	[546,851,722]	8	hSpCas9	negative selection	5343503
39173598	39173620	19	+	27760321	HT29	viability after 10 days	CTAACGGGCCATCAGCGGGGGG	PAK4	ENSG00000130669	0.33771666022242486	[588,459]	[869,873,741]	4	hSpCas9	negative selection	5343504
39173880	39173902	19	+	27760321	HT29	viability after 10 days	ACTTCATCAAGATTGGCGAGGG	PAK4	ENSG00000130669	-0.4722900004204099	[646,504]	[367,663,526]	-5	hSpCas9	negative selection	5343505
39174925	39174947	19	+	27760321	HT29	viability after 10 days	GCACAGGTGGTAATCATGAGGG	PAK4	ENSG00000130669	0.6432489258123917	[192,150]	[124,342,533]	8	hSpCas9	negative selection	5343506
39169676	39169698	19	-	27760321	MOLM13	viability	GCGAGCCGACTCCTCGATCAGG	PAK4	ENSG00000130669	0.18331565739094935	[736,606]	[414,439]	1	hSpCas9	negative selection	5426965
39173584	39173606	19	+	27760321	MOLM13	viability	TCATGACGTGGCCCCTAACGGG	PAK4	ENSG00000130669	0.5587123178898329	[506,391]	[661,122]	4	hSpCas9	negative selection	5426966
39173598	39173620	19	+	27760321	MOLM13	viability	CTAACGGGCCATCAGCGGGGGG	PAK4	ENSG00000130669	-0.07326693075218527	[821,588]	[428,327]	0	hSpCas9	negative selection	5426967
39173880	39173902	19	+	27760321	MOLM13	viability	ACTTCATCAAGATTGGCGAGGG	PAK4	ENSG00000130669	-0.6990947943363559	[705,646]	[274,200]	-4	hSpCas9	negative selection	5426968
39174925	39174947	19	+	27760321	MOLM13	viability	GCACAGGTGGTAATCATGAGGG	PAK4	ENSG00000130669	-0.7842597320101142	[294,192]	[60,93]	-5	hSpCas9	negative selection	5426969
39125810	39125833	19	+	27661255	K562	viability	GGCGGCGGGAGTGTCCGCGGTGG	PAK4	ENSG00000130669	0.0817077484490244	[429,422]	[378,344]	3	dCas9-KRAB	negative selection	5500002
39125813	39125836	19	+	27661255	K562	viability	GGCGGGAGTGTCCGCGGTGGTGG	PAK4	ENSG00000130669	-0.3808625433535884	[145,234]	[103,125]	-7	dCas9-KRAB	negative selection	5500003
39126223	39126246	19	+	27661255	K562	viability	GCTGCCCCCACGAGGGTCAGAGG	PAK4	ENSG00000130669	0.11110194156689573	[772,525]	[608,525]	4	dCas9-KRAB	negative selection	5500004
39126237	39126260	19	+	27661255	K562	viability	GGTCAGAGGTCACAGCCCCAGGG	PAK4	ENSG00000130669	-0.01731376440925922	[598,739]	[601,461]	0	dCas9-KRAB	negative selection	5500005
39126227	39126250	19	-	27661255	K562	viability	GTGACCTCTGACCCTCGTGGGGG	PAK4	ENSG00000130669	-0.16641393009328243	[457,593]	[444,310]	-5	dCas9-KRAB	negative selection	5500006
39173904	39173927	19	-	27260156	BXPC3	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.06592772098867594	[142]	[143,194,139,142]	1	hSpCas9	negative selection	5561158
39173321	39173344	19	+	27260156	BXPC3	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.12494824926551673	[336]	[393,356,300,494]	2	hSpCas9	negative selection	5561159
39173798	39173821	19	-	27260156	BXPC3	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.09005216284164153	[113]	[117,126,113,82]	-2	hSpCas9	negative selection	5561160
39172919	39172942	19	-	27260156	BXPC3	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.044652304678802546	[898]	[806,889,813,1170]	-1	hSpCas9	negative selection	5625411
39174923	39174946	19	+	27260156	BXPC3	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.06867686269615414	[742]	[678,528,896,893]	-2	hSpCas9	negative selection	5625412
39174951	39174974	19	-	27260156	BXPC3	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.3893643854868647	[907]	[712,622,789,783]	-7	hSpCas9	negative selection	5625413
39173904	39173927	19	-	27260156	A673	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.05793137669774362	[142]	[218,111,191,198]	1	hSpCas9	negative selection	5682409
39173321	39173344	19	+	27260156	A673	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.47054044002185147	[336]	[555,635,410,641]	9	hSpCas9	negative selection	5682410
39173798	39173821	19	-	27260156	A673	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	0.010107599317227045	[113]	[163,130,98,161]	0	hSpCas9	negative selection	5682411
39172919	39172942	19	-	27260156	A673	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.022841513852200013	[898]	[1233,949,1049,1174]	0	hSpCas9	negative selection	5746662
39174923	39174946	19	+	27260156	A673	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.11507056027460272	[742]	[900,792,776,832]	-3	hSpCas9	negative selection	5746663
39174951	39174974	19	-	27260156	A673	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.357730924452452	[907]	[968,795,744,910]	-7	hSpCas9	negative selection	5746664
39173904	39173927	19	-	27260156	A375	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.7372354211064361	[142]	[170,350,192,392]	9	hSpCas9	negative selection	5803660
39173321	39173344	19	+	27260156	A375	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.15617779180927233	[336]	[432,441,594,299]	2	hSpCas9	negative selection	5803661
39173798	39173821	19	-	27260156	A375	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.5216286108825976	[113]	[82,124,119,51]	-6	hSpCas9	negative selection	5803662
39172919	39172942	19	-	27260156	A375	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.20257690747893753	[898]	[837,1208,699,936]	-3	hSpCas9	negative selection	5867913
39174923	39174946	19	+	27260156	A375	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.7758649478303417	[742]	[490,689,540,347]	-7	hSpCas9	negative selection	5867914
39174951	39174974	19	-	27260156	A375	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.2617761512375345	[907]	[765,580,985,1128]	-4	hSpCas9	negative selection	5867915
39173904	39173927	19	-	27260156	COLO741	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.5781931481357603	[142]	[199,300,307]	9	hSpCas9	negative selection	5924911
39173321	39173344	19	+	27260156	COLO741	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.010282910063307338	[336]	[434,540,331]	0	hSpCas9	negative selection	5924912
39173798	39173821	19	-	27260156	COLO741	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	0.4001516586574796	[113]	[310,123,153]	7	hSpCas9	negative selection	5924913
39172919	39172942	19	-	27260156	COLO741	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.09985912644499417	[898]	[1508,1137,1077]	2	hSpCas9	negative selection	5989164
39174923	39174946	19	+	27260156	COLO741	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	0.010294212654753165	[742]	[951,958,954]	0	hSpCas9	negative selection	5989165
39174951	39174974	19	-	27260156	COLO741	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.03662737049749487	[907]	[1102,1204,1083]	-1	hSpCas9	negative selection	5989166
39173904	39173927	19	-	27260156	CAL120	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.2972043149302275	[142]	[307,124,235]	4	hSpCas9	negative selection	6046162
39173321	39173344	19	+	27260156	CAL120	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-0.05352066998378524	[336]	[442,317,455]	-1	hSpCas9	negative selection	6046163
39173798	39173821	19	-	27260156	CAL120	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.30925335256369557	[113]	[82,102,151]	-4	hSpCas9	negative selection	6046164
39172919	39172942	19	-	27260156	CAL120	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.05803942589799316	[898]	[1185,1197,859]	-1	hSpCas9	negative selection	6110415
39174923	39174946	19	+	27260156	CAL120	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	0.1768332983944817	[742]	[1040,1138,955]	2	hSpCas9	negative selection	6110416
39174951	39174974	19	-	27260156	CAL120	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.3651063357335147	[907]	[659,1130,808]	-5	hSpCas9	negative selection	6110417
39173904	39173927	19	-	27260156	CADOES1	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.028145197044953996	[142]	[122,131,138,148]	0	hSpCas9	negative selection	6167413
39173321	39173344	19	+	27260156	CADOES1	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.21834847162670057	[336]	[307,362,440,345]	3	hSpCas9	negative selection	6167414
39173798	39173821	19	-	27260156	CADOES1	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.30750953081804466	[113]	[64,77,106,92]	-5	hSpCas9	negative selection	6167415
39172919	39172942	19	-	27260156	CADOES1	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.026279716875102888	[898]	[839,773,898,768]	0	hSpCas9	negative selection	6231666
39174923	39174946	19	+	27260156	CADOES1	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.3801300797413056	[742]	[642,526,437,514]	-6	hSpCas9	negative selection	6231667
39174951	39174974	19	-	27260156	CADOES1	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.41400809636831726	[907]	[622,678,762,463]	-6	hSpCas9	negative selection	6231668
39173904	39173927	19	-	27260156	EWS502	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.4385791778171524	[142]	[78,86,165,120]	-6	hSpCas9	negative selection	6288664
39173321	39173344	19	+	27260156	EWS502	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.2583764369932561	[336]	[307,391,490,539]	4	hSpCas9	negative selection	6288665
39173798	39173821	19	-	27260156	EWS502	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	0.02726885829165715	[113]	[53,123,137,188]	0	hSpCas9	negative selection	6288666
39172919	39172942	19	-	27260156	EWS502	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.014662321708364234	[898]	[1002,997,893,939]	0	hSpCas9	negative selection	6352917
39174923	39174946	19	+	27260156	EWS502	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.15174191598847508	[742]	[675,670,738,753]	-3	hSpCas9	negative selection	6352918
39174951	39174974	19	-	27260156	EWS502	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.3320679436649784	[907]	[720,675,673,1006]	-5	hSpCas9	negative selection	6352919
39173904	39173927	19	-	27260156	EW8	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.012361928698205737	[142]	[155,85,70,157]	0	hSpCas9	negative selection	6409915
39173321	39173344	19	+	27260156	EW8	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-0.06160075105607721	[336]	[184,308,229,318]	-1	hSpCas9	negative selection	6409916
39173798	39173821	19	-	27260156	EW8	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.2307986603432548	[113]	[85,18,96,109]	-4	hSpCas9	negative selection	6409917
39172919	39172942	19	-	27260156	EW8	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.2702888841562665	[898]	[764,567,510,603]	-5	hSpCas9	negative selection	6474168
39174923	39174946	19	+	27260156	EW8	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.7748700438461678	[742]	[394,332,299,391]	-8	hSpCas9	negative selection	6474169
39174951	39174974	19	-	27260156	EW8	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.7063855767025357	[907]	[669,347,435,374]	-8	hSpCas9	negative selection	6474170
39173904	39173927	19	-	27260156	CORL105	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.2687824103107317	[142]	[175,176,153,51]	-5	hSpCas9	negative selection	6531166
39173321	39173344	19	+	27260156	CORL105	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-0.06636700978528476	[336]	[287,449,348,410]	-1	hSpCas9	negative selection	6531167
39173798	39173821	19	-	27260156	CORL105	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.656273108529585	[113]	[124,95,52,60]	-8	hSpCas9	negative selection	6531168
39172919	39172942	19	-	27260156	CORL105	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.07730937484011535	[898]	[957,1017,1222,824]	-1	hSpCas9	negative selection	6595419
39174923	39174946	19	+	27260156	CORL105	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.5221996215711507	[742]	[430,729,681,582]	-7	hSpCas9	negative selection	6595420
39174951	39174974	19	-	27260156	CORL105	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.5870840680322886	[907]	[675,846,739,568]	-8	hSpCas9	negative selection	6595421
39173904	39173927	19	-	27260156	HS294T	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.036792099266775846	[142]	[53,46,80,42]	0	hSpCas9	negative selection	6652417
39173321	39173344	19	+	27260156	HS294T	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-0.43756357177136773	[336]	[58,89,99,147]	-6	hSpCas9	negative selection	6652418
39173798	39173821	19	-	27260156	HS294T	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.33296917801773374	[113]	[27,40,37,32]	-5	hSpCas9	negative selection	6652419
39172919	39172942	19	-	27260156	HS294T	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.06956321498261109	[898]	[244,254,332,535]	-1	hSpCas9	negative selection	6716670
39174923	39174946	19	+	27260156	HS294T	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.637063309328055	[742]	[98,146,206,316]	-7	hSpCas9	negative selection	6716671
39174951	39174974	19	-	27260156	HS294T	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.288141220449884	[907]	[233,163,410,361]	-4	hSpCas9	negative selection	6716672
39173904	39173927	19	-	27260156	HCC44	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.3644862014870234	[142]	[91,191,253,289]	6	hSpCas9	negative selection	6773668
39173321	39173344	19	+	27260156	HCC44	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.5618548228572057	[336]	[606,341,538,781]	8	hSpCas9	negative selection	6773669
39173798	39173821	19	-	27260156	HCC44	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.06137433551217253	[113]	[119,8,173,211]	-1	hSpCas9	negative selection	6773670
39172919	39172942	19	-	27260156	HCC44	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.2646625839815444	[898]	[1523,920,1554,1010]	4	hSpCas9	negative selection	6837921
39174923	39174946	19	+	27260156	HCC44	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.2642676845674654	[742]	[713,834,671,553]	-4	hSpCas9	negative selection	6837922
39174951	39174974	19	-	27260156	HCC44	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.28970013176941234	[907]	[805,658,1031,909]	-4	hSpCas9	negative selection	6837923
39173904	39173927	19	-	27260156	G402	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.5180677606992616	[142]	[515,201,104,212]	6	hSpCas9	negative selection	6894919
39173321	39173344	19	+	27260156	G402	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.29340643575736336	[336]	[867,366,521,310]	3	hSpCas9	negative selection	6894920
39173798	39173821	19	-	27260156	G402	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	0.2652225452357202	[113]	[314,42,258,69]	3	hSpCas9	negative selection	6894921
39172919	39172942	19	-	27260156	G402	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.03569469429004879	[898]	[1578,1086,1044,858]	0	hSpCas9	negative selection	6959172
39174923	39174946	19	+	27260156	G402	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.5783595783411819	[742]	[938,502,477,550]	-6	hSpCas9	negative selection	6959173
39174951	39174974	19	-	27260156	G402	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.21052804962768423	[907]	[1242,951,688,981]	-3	hSpCas9	negative selection	6959174
39173904	39173927	19	-	27260156	L33	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.22299799945622856	[142]	[116,36,113,101]	-5	hSpCas9	negative selection	7016170
39173321	39173344	19	+	27260156	L33	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-0.06801020468965246	[336]	[345,149,186,275]	-1	hSpCas9	negative selection	7016171
39173798	39173821	19	-	27260156	L33	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.05108431328511864	[113]	[99,20,78,162]	-1	hSpCas9	negative selection	7016172
39172919	39172942	19	-	27260156	L33	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.06817444137419715	[898]	[846,401,689,847]	1	hSpCas9	negative selection	7080423
39174923	39174946	19	+	27260156	L33	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.4747355029868824	[742]	[536,204,369,512]	-8	hSpCas9	negative selection	7080424
39174951	39174974	19	-	27260156	L33	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.34444793055138867	[907]	[750,303,476,608]	-7	hSpCas9	negative selection	7080425
39173904	39173927	19	-	27260156	K562	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.5783690325817303	[142]	[210,183,158,202]	7	hSpCas9	negative selection	7137421
39173321	39173344	19	+	27260156	K562	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.43371020650096037	[336]	[261,519,294,517]	5	hSpCas9	negative selection	7137422
39173798	39173821	19	-	27260156	K562	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-1.4612403641103708	[113]	[76,24,24,23]	-9	hSpCas9	negative selection	7137423
39172919	39172942	19	-	27260156	K562	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.0019026304826258444	[898]	[802,941,746,709]	0	hSpCas9	negative selection	7201674
39174923	39174946	19	+	27260156	K562	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.40213678972457845	[742]	[379,644,621,360]	-5	hSpCas9	negative selection	7201675
39174951	39174974	19	-	27260156	K562	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	0.009649605043491993	[907]	[706,821,1304,442]	0	hSpCas9	negative selection	7201676
39173904	39173927	19	-	27260156	HT29	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.3730821682913448	[142]	[253,317,200,145]	7	hSpCas9	negative selection	7258672
39173321	39173344	19	+	27260156	HT29	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.24755583635432382	[336]	[546,447,468,479]	5	hSpCas9	negative selection	7258673
39173798	39173821	19	-	27260156	HT29	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.45312256465574974	[113]	[99,109,139,59]	-7	hSpCas9	negative selection	7258674
39172919	39172942	19	-	27260156	HT29	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.0481233109741932	[898]	[851,1048,1184,1110]	-1	hSpCas9	negative selection	7322925
39174923	39174946	19	+	27260156	HT29	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.27732620567886007	[742]	[896,754,733,617]	-5	hSpCas9	negative selection	7322926
39174951	39174974	19	-	27260156	HT29	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.5040924251829777	[907]	[873,666,765,795]	-7	hSpCas9	negative selection	7322927
39173904	39173927	19	-	27260156	MHHES1	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.1024379908491364	[142]	[216,156,173,148]	2	hSpCas9	negative selection	7379923
39173321	39173344	19	+	27260156	MHHES1	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.20320127041055025	[336]	[486,494,441,346]	4	hSpCas9	negative selection	7379924
39173798	39173821	19	-	27260156	MHHES1	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.3575684640819121	[113]	[101,66,148,81]	-6	hSpCas9	negative selection	7379925
39172919	39172942	19	-	27260156	MHHES1	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.07149569901437713	[898]	[1040,1343,1089,835]	1	hSpCas9	negative selection	7444176
39174923	39174946	19	+	27260156	MHHES1	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.07365447537553726	[742]	[1296,935,507,551]	-1	hSpCas9	negative selection	7444177
39174951	39174974	19	-	27260156	MHHES1	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.24845976994673824	[907]	[940,1050,675,797]	-5	hSpCas9	negative selection	7444178
39173904	39173927	19	-	27260156	MEWO	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.7980389007987729	[142]	[288,175,243]	9	hSpCas9	negative selection	7501174
39173321	39173344	19	+	27260156	MEWO	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.00588874543765866	[336]	[323,334,291]	0	hSpCas9	negative selection	7501175
39173798	39173821	19	-	27260156	MEWO	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.6186659451043184	[113]	[66,46,93]	-8	hSpCas9	negative selection	7501176
39172919	39172942	19	-	27260156	MEWO	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.01926835398350235	[898]	[886,749,863]	0	hSpCas9	negative selection	7565427
39174923	39174946	19	+	27260156	MEWO	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.32629765595554555	[742]	[562,510,590]	-6	hSpCas9	negative selection	7565428
39174951	39174974	19	-	27260156	MEWO	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.365387393087911	[907]	[803,687,513]	-7	hSpCas9	negative selection	7565429
39173904	39173927	19	-	27260156	LNCAPCLONEFGC	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.324497016930986	[142]	[220,102,205,127]	5	hSpCas9	negative selection	7622425
39173321	39173344	19	+	27260156	LNCAPCLONEFGC	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.7988026583315936	[336]	[551,397,656,543]	9	hSpCas9	negative selection	7622426
39173798	39173821	19	-	27260156	LNCAPCLONEFGC	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.07835627132678535	[113]	[195,34,121,43]	-1	hSpCas9	negative selection	7622427
39172919	39172942	19	-	27260156	LNCAPCLONEFGC	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.68408694428549	[898]	[1168,1167,1430,1494]	9	hSpCas9	negative selection	7686678
39174923	39174946	19	+	27260156	LNCAPCLONEFGC	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	0.6282184788844418	[742]	[988,1017,1336,862]	8	hSpCas9	negative selection	7686679
39174951	39174974	19	-	27260156	LNCAPCLONEFGC	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.16303135831120474	[907]	[624,654,805,869]	-3	hSpCas9	negative selection	7686680
39173904	39173927	19	-	27260156	PANC0327	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.2915116982365322	[142]	[134,110,214,164]	4	hSpCas9	negative selection	7743676
39173321	39173344	19	+	27260156	PANC0327	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-0.35499755604160843	[336]	[245,196,269,228]	-5	hSpCas9	negative selection	7743677
39173798	39173821	19	-	27260156	PANC0327	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-1.9441400277599072	[113]	[12,19,39,31]	-9	hSpCas9	negative selection	7743678
39172919	39172942	19	-	27260156	PANC0327	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.23785558486744862	[898]	[630,737,674,652]	-4	hSpCas9	negative selection	7807929
39174923	39174946	19	+	27260156	PANC0327	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.7343943103685782	[742]	[490,431,397,268]	-7	hSpCas9	negative selection	7807930
39174951	39174974	19	-	27260156	PANC0327	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.332658534930263	[907]	[482,498,683,900]	-5	hSpCas9	negative selection	7807931
39173904	39173927	19	-	27260156	NCIH2009	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.08696837122794498	[142]	[306,101,247]	1	hSpCas9	negative selection	7864927
39173321	39173344	19	+	27260156	NCIH2009	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-0.1746513573328734	[336]	[505,434,326]	-2	hSpCas9	negative selection	7864928
39173798	39173821	19	-	27260156	NCIH2009	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-1.0222033766889718	[113]	[155,48,45]	-8	hSpCas9	negative selection	7864929
39172919	39172942	19	-	27260156	NCIH2009	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.06410938087996565	[898]	[1407,1153,1081]	-1	hSpCas9	negative selection	7929180
39174923	39174946	19	+	27260156	NCIH2009	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.6745057910326511	[742]	[682,846,422]	-7	hSpCas9	negative selection	7929181
39174951	39174974	19	-	27260156	NCIH2009	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.6605766684728218	[907]	[932,752,746]	-7	hSpCas9	negative selection	7929182
39173904	39173927	19	-	27260156	NCIH1373	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.03163398915440663	[142]	[194,241,111,25]	0	hSpCas9	negative selection	7986178
39173321	39173344	19	+	27260156	NCIH1373	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-0.7738425348844746	[336]	[172,138,169,108]	-7	hSpCas9	negative selection	7986179
39173798	39173821	19	-	27260156	NCIH1373	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.7712656475482005	[113]	[25,121,72,16]	-7	hSpCas9	negative selection	7986180
39172919	39172942	19	-	27260156	NCIH1373	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.3990455433950364	[898]	[677,923,817,154]	-4	hSpCas9	negative selection	8050431
39174923	39174946	19	+	27260156	NCIH1373	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-1.104007334233835	[742]	[515,229,305,142]	-8	hSpCas9	negative selection	8050432
39174951	39174974	19	-	27260156	NCIH1373	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.2872295180027248	[907]	[1345,620,627,221]	-3	hSpCas9	negative selection	8050433
39173904	39173927	19	-	27260156	PATU8902	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.43124643795204576	[142]	[246,323,211,308]	4	hSpCas9	negative selection	8107429
39173321	39173344	19	+	27260156	PATU8902	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.28196941567788103	[336]	[438,887,656,233]	3	hSpCas9	negative selection	8107430
39173798	39173821	19	-	27260156	PATU8902	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.49861718738794236	[113]	[220,222,8,8]	-5	hSpCas9	negative selection	8107431
39172919	39172942	19	-	27260156	PATU8902	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.13071213529546966	[898]	[1645,1540,1125,1198]	1	hSpCas9	negative selection	8171682
39174923	39174946	19	+	27260156	PATU8902	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.41155632931476277	[742]	[549,533,706,1410]	-4	hSpCas9	negative selection	8171683
39174951	39174974	19	-	27260156	PATU8902	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.8885151848171421	[907]	[762,796,508,704]	-7	hSpCas9	negative selection	8171684
39173904	39173927	19	-	27260156	PANC1	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.8414237929887238	[142]	[56,72,73,69]	-8	hSpCas9	negative selection	8228680
39173321	39173344	19	+	27260156	PANC1	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-1.1392326384884457	[336]	[101,60,160,177]	-8	hSpCas9	negative selection	8228681
39173798	39173821	19	-	27260156	PANC1	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-1.841898317892071	[113]	[71,27,2,7]	-9	hSpCas9	negative selection	8228682
39172919	39172942	19	-	27260156	PANC1	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.4610534121929631	[898]	[620,580,490,545]	-6	hSpCas9	negative selection	8292933
39174923	39174946	19	+	27260156	PANC1	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-1.2823964474850222	[742]	[243,278,290,238]	-9	hSpCas9	negative selection	8292934
39174951	39174974	19	-	27260156	PANC1	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-1.2083736836738468	[907]	[407,405,258,290]	-9	hSpCas9	negative selection	8292935
39173904	39173927	19	-	27260156	PANC0813	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.6410392140699879	[142]	[369,307,191,190]	8	hSpCas9	negative selection	8349931
39173321	39173344	19	+	27260156	PANC0813	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-0.10406030974697145	[336]	[404,496,253,321]	-2	hSpCas9	negative selection	8349932
39173798	39173821	19	-	27260156	PANC0813	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.913940298613821	[113]	[85,43,90,64]	-8	hSpCas9	negative selection	8349933
39172919	39172942	19	-	27260156	PANC0813	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.12675414726219292	[898]	[1047,1425,1070,1059]	2	hSpCas9	negative selection	8414184
39174923	39174946	19	+	27260156	PANC0813	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.5089398047108769	[742]	[645,654,627,530]	-6	hSpCas9	negative selection	8414185
39174951	39174974	19	-	27260156	PANC0813	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.7906955186668762	[907]	[762,524,632,560]	-8	hSpCas9	negative selection	8414186
39173904	39173927	19	-	27260156	RDES	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.5574103334223981	[142]	[219,287,221,226]	8	hSpCas9	negative selection	8471182
39173321	39173344	19	+	27260156	RDES	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.420788460790592	[336]	[360,559,630,546]	6	hSpCas9	negative selection	8471183
39173798	39173821	19	-	27260156	RDES	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.3181523884070412	[113]	[75,133,97,113]	-5	hSpCas9	negative selection	8471184
39172919	39172942	19	-	27260156	RDES	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.020569571504862605	[898]	[821,1029,1090,1169]	0	hSpCas9	negative selection	8535435
39174923	39174946	19	+	27260156	RDES	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.3187338331715815	[742]	[587,644,802,716]	-5	hSpCas9	negative selection	8535436
39174951	39174974	19	-	27260156	RDES	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.18352915502476463	[907]	[708,884,983,1160]	-3	hSpCas9	negative selection	8535437
39173904	39173927	19	-	27260156	PC3	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.05383439544905899	[142]	[109,160,236,115]	1	hSpCas9	negative selection	8592433
39173321	39173344	19	+	27260156	PC3	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.3240392633894936	[336]	[258,326,1021,341]	7	hSpCas9	negative selection	8592434
39173798	39173821	19	-	27260156	PC3	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.3474908137822408	[113]	[24,60,173,158]	-7	hSpCas9	negative selection	8592435
39172919	39172942	19	-	27260156	PC3	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.134267706190343	[898]	[605,1110,1457,1006]	3	hSpCas9	negative selection	8656686
39174923	39174946	19	+	27260156	PC3	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.32322089675197907	[742]	[411,566,951,593]	-6	hSpCas9	negative selection	8656687
39174951	39174974	19	-	27260156	PC3	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.5305641009716697	[907]	[354,663,1196,570]	-8	hSpCas9	negative selection	8656688
39173904	39173927	19	-	27260156	PATU8988T	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.3684053739104445	[142]	[223,242,45,210]	6	hSpCas9	negative selection	8713684
39173321	39173344	19	+	27260156	PATU8988T	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-0.5069232231292268	[336]	[152,159,250,355]	-7	hSpCas9	negative selection	8713685
39173798	39173821	19	-	27260156	PATU8988T	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-2.935284025515492	[113]	[7,19,6,23]	-9	hSpCas9	negative selection	8713686
39172919	39172942	19	-	27260156	PATU8988T	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.35279404596925856	[898]	[824,403,750,716]	-5	hSpCas9	negative selection	8777937
39174923	39174946	19	+	27260156	PATU8988T	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-1.5793618672585419	[742]	[159,252,309,237]	-9	hSpCas9	negative selection	8777938
39174951	39174974	19	-	27260156	PATU8988T	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.8353280558119748	[907]	[484,503,370,619]	-8	hSpCas9	negative selection	8777939
39173904	39173927	19	-	27260156	T47D	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.06857101276855704	[142]	[155,134,166,179]	-1	hSpCas9	negative selection	8834935
39173321	39173344	19	+	27260156	T47D	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.4291882753845822	[336]	[524,515,588,482]	8	hSpCas9	negative selection	8834936
39173798	39173821	19	-	27260156	T47D	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.5164907943143975	[113]	[95,73,83,119]	-8	hSpCas9	negative selection	8834937
39172919	39172942	19	-	27260156	T47D	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.004668840875969971	[898]	[980,878,1184,1173]	0	hSpCas9	negative selection	8899188
39174923	39174946	19	+	27260156	T47D	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.17523202459924153	[742]	[815,660,677,926]	-4	hSpCas9	negative selection	8899189
39174951	39174974	19	-	27260156	T47D	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.40392041603569084	[907]	[863,751,792,792]	-7	hSpCas9	negative selection	8899190
39173904	39173927	19	-	27260156	SU8686	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.5106895100254207	[142]	[120,89,51,137]	-7	hSpCas9	negative selection	8956186
39173321	39173344	19	+	27260156	SU8686	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	-1.508800989534576	[336]	[149,121,74,115]	-9	hSpCas9	negative selection	8956187
39173798	39173821	19	-	27260156	SU8686	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-1.845400000839052	[113]	[63,22,10,22]	-9	hSpCas9	negative selection	8956188
39172919	39172942	19	-	27260156	SU8686	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.7431489128022047	[898]	[489,510,617,513]	-8	hSpCas9	negative selection	9020439
39174923	39174946	19	+	27260156	SU8686	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-1.4693985131581058	[742]	[235,173,376,298]	-9	hSpCas9	negative selection	9020440
39174951	39174974	19	-	27260156	SU8686	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.9810574928424579	[907]	[448,398,464,527]	-8	hSpCas9	negative selection	9020441
39173904	39173927	19	-	27260156	SKES1	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.23974127765582054	[142]	[126,140,90,125]	-5	hSpCas9	negative selection	9077437
39173321	39173344	19	+	27260156	SKES1	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.40027239956287497	[336]	[500,478,460,351]	7	hSpCas9	negative selection	9077438
39173798	39173821	19	-	27260156	SKES1	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.37064080766424157	[113]	[151,48,72,81]	-7	hSpCas9	negative selection	9077439
39172919	39172942	19	-	27260156	SKES1	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	-0.019232675315329684	[898]	[1073,834,964,697]	0	hSpCas9	negative selection	9141690
39174923	39174946	19	+	27260156	SKES1	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.22148698137078343	[742]	[885,764,462,491]	-5	hSpCas9	negative selection	9141691
39174951	39174974	19	-	27260156	SKES1	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.30564342463167515	[907]	[1019,556,804,577]	-6	hSpCas9	negative selection	9141692
39173904	39173927	19	-	27260156	TOV112D	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.07057946052583275	[142]	[192,108,128,112]	-1	hSpCas9	negative selection	9198688
39173321	39173344	19	+	27260156	TOV112D	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.49331063594476154	[336]	[471,621,417,424]	8	hSpCas9	negative selection	9198689
39173798	39173821	19	-	27260156	TOV112D	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.0421217225762871	[113]	[76,209,69,107]	-1	hSpCas9	negative selection	9198690
39172919	39172942	19	-	27260156	TOV112D	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.3390490068925991	[898]	[1171,1364,999,1076]	6	hSpCas9	negative selection	9262941
39174923	39174946	19	+	27260156	TOV112D	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.10949106526370433	[742]	[610,1200,552,516]	-2	hSpCas9	negative selection	9262942
39174951	39174974	19	-	27260156	TOV112D	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.5437560599249295	[907]	[643,846,655,409]	-8	hSpCas9	negative selection	9262943
39173904	39173927	19	-	27260156	TC71	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.33318293711451963	[142]	[200,205,161,204]	7	hSpCas9	negative selection	9319939
39173321	39173344	19	+	27260156	TC71	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.19018150557923758	[336]	[387,454,420,382]	5	hSpCas9	negative selection	9319940
39173798	39173821	19	-	27260156	TC71	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	0.07590296553479403	[113]	[151,168,73,120]	2	hSpCas9	negative selection	9319941
39172919	39172942	19	-	27260156	TC71	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.15289826012309726	[898]	[1002,1078,1092,1113]	4	hSpCas9	negative selection	9384192
39174923	39174946	19	+	27260156	TC71	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.123510792420366	[742]	[644,734,728,822]	-3	hSpCas9	negative selection	9384193
39174951	39174974	19	-	27260156	TC71	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.4883607447599749	[907]	[672,664,752,681]	-8	hSpCas9	negative selection	9384194
39173904	39173927	19	-	27260156	TC32	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.22790094522514215	[142]	[153,133,225,124]	4	hSpCas9	negative selection	9441190
39173321	39173344	19	+	27260156	TC32	viability	GGCCCTTTAACACCTACCCGAGG	PAK4	ENSG00000130669	0.3009534350962514	[336]	[355,336,534,355]	5	hSpCas9	negative selection	9441191
39173798	39173821	19	-	27260156	TC32	viability	TGCTCATGGGATACTCGCTGTGG	PAK4	ENSG00000130669	-0.3199007976202375	[113]	[76,46,157,84]	-5	hSpCas9	negative selection	9441192
39172919	39172942	19	-	27260156	TC32	viability	ACCTTTGCTGCCCCGCACGATGG	PAK4	ENSG00000130669	0.04865001286724313	[898]	[802,586,955,1251]	0	hSpCas9	negative selection	9505443
39174923	39174946	19	+	27260156	TC32	viability	CTGCACAGGTGGTAATCATGAGG	PAK4	ENSG00000130669	-0.33401227750169316	[742]	[561,344,869,538]	-6	hSpCas9	negative selection	9505444
39174951	39174974	19	-	27260156	TC32	viability	TCTCCACCACATTCTCGTGCTGG	PAK4	ENSG00000130669	-0.09156544495246277	[907]	[839,515,1176,790]	-2	hSpCas9	negative selection	9505445
39169546	39169569	19	+	27869803	HPAFII	viability after 27 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-0.6697632099003943	[882]	[443,164,NaN]	-5	hSpCas9	negative selection	9567657
39173249	39173272	19	-	27869803	HPAFII	viability after 27 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	0.9373430896504109	[240]	[240,243,NaN]	7	hSpCas9	negative selection	9567658
39173596	39173619	19	+	27869803	HPAFII	viability after 27 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-0.4990363673080863	[162]	[70,51,NaN]	-4	hSpCas9	negative selection	9567659
39175043	39175066	19	+	27869803	HPAFII	viability after 27 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.0617156626648343	[646]	[314,334,NaN]	0	hSpCas9	negative selection	9567660
39175374	39175397	19	+	27869803	HPAFII	viability after 27 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	0.29547217402860637	[40]	[20,30,NaN]	2	hSpCas9	negative selection	9567661
39176693	39176716	19	-	27869803	HPAFII	viability after 27 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-1.3243817939591465	[235]	[30,64,NaN]	-7	hSpCas9	negative selection	9567662
39169546	39169569	19	+	27869803	HPAFII	viability after 15 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-0.26714766708405047	[882]	[1004,653,NaN]	-3	hSpCas9	negative selection	9650106
39173249	39173272	19	-	27869803	HPAFII	viability after 15 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	0.4236020632553527	[240]	[376,328,NaN]	5	hSpCas9	negative selection	9650107
39173596	39173619	19	+	27869803	HPAFII	viability after 15 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	0.2177348679172808	[162]	[228,187,NaN]	2	hSpCas9	negative selection	9650108
39175043	39175066	19	+	27869803	HPAFII	viability after 15 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	0.57776369607989	[646]	[1392,816,NaN]	6	hSpCas9	negative selection	9650109
39175374	39175397	19	+	27869803	HPAFII	viability after 15 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	0.6329664425765669	[40]	[55,75,NaN]	7	hSpCas9	negative selection	9650110
39176693	39176716	19	-	27869803	HPAFII	viability after 15 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-0.319825618591472	[235]	[254,170,NaN]	-4	hSpCas9	negative selection	9650111
39169546	39169569	19	+	27869803	ASPC1	viability after 36 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	0.6424304551296673	[1820]	[783,1529,700]	6	hSpCas9	negative selection	9732555
39173249	39173272	19	-	27869803	ASPC1	viability after 36 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	0.7619694338089757	[490]	[168,214,432]	7	hSpCas9	negative selection	9732556
39173596	39173619	19	+	27869803	ASPC1	viability after 36 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-0.16271021415474962	[379]	[145,91,118]	-2	hSpCas9	negative selection	9732557
39175043	39175066	19	+	27869803	ASPC1	viability after 36 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	0.16114440065051294	[1306]	[482,645,415]	1	hSpCas9	negative selection	9732558
39175374	39175397	19	+	27869803	ASPC1	viability after 36 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	0.03687196662156644	[93]	[50,53,4]	0	hSpCas9	negative selection	9732559
39176693	39176716	19	-	27869803	ASPC1	viability after 36 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-0.8149388213845237	[559]	[51,156,114]	-7	hSpCas9	negative selection	9732560
39169546	39169569	19	+	27869803	PATU8988S	viability after 35 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-0.3667594455465142	[1803]	[547,578,NaN]	-4	hSpCas9	negative selection	9815004
39173249	39173272	19	-	27869803	PATU8988S	viability after 35 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	0.3286517518092197	[528]	[294,239,NaN]	4	hSpCas9	negative selection	9815005
39173596	39173619	19	+	27869803	PATU8988S	viability after 35 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	0.7629819529569647	[364]	[233,264,NaN]	7	hSpCas9	negative selection	9815006
39175043	39175066	19	+	27869803	PATU8988S	viability after 35 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.1644157749612012	[1288]	[343,582,NaN]	-2	hSpCas9	negative selection	9815007
39175374	39175397	19	+	27869803	PATU8988S	viability after 35 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	1.4787228896493876	[80]	[55,125,NaN]	9	hSpCas9	negative selection	9815008
39176693	39176716	19	-	27869803	PATU8988S	viability after 35 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	0.41956902617276115	[327]	[259,92,NaN]	5	hSpCas9	negative selection	9815009
39169546	39169569	19	+	27869803	PATU8988S	viability after 31 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-0.5790870762313325	[1803]	[444,527,NaN]	-6	hSpCas9	negative selection	9897453
39173249	39173272	19	-	27869803	PATU8988S	viability after 31 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	-0.07601560429708992	[528]	[145,268,NaN]	-1	hSpCas9	negative selection	9897454
39173596	39173619	19	+	27869803	PATU8988S	viability after 31 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	0.7721522389541624	[364]	[237,261,NaN]	8	hSpCas9	negative selection	9897455
39175043	39175066	19	+	27869803	PATU8988S	viability after 31 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.07846330020566827	[1288]	[356,651,NaN]	-1	hSpCas9	negative selection	9897456
39175374	39175397	19	+	27869803	PATU8988S	viability after 31 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	1.1362721525260573	[80]	[48,98,NaN]	9	hSpCas9	negative selection	9897457
39176693	39176716	19	-	27869803	PATU8988S	viability after 31 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-0.4021908919509639	[327]	[138,47,NaN]	-4	hSpCas9	negative selection	9897458
39169546	39169569	19	+	27869803	HPAFII	viability after 35 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-1.4514353877746409	[882]	[249,65,NaN]	-7	hSpCas9	negative selection	9979902
39173249	39173272	19	-	27869803	HPAFII	viability after 35 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	1.2752966239150345	[240]	[212,387,NaN]	8	hSpCas9	negative selection	9979903
39173596	39173619	19	+	27869803	HPAFII	viability after 35 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-0.5191179689518742	[162]	[42,73,NaN]	-3	hSpCas9	negative selection	9979904
39175043	39175066	19	+	27869803	HPAFII	viability after 35 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.4718275408081133	[646]	[230,241,NaN]	-3	hSpCas9	negative selection	9979905
39175374	39175397	19	+	27869803	HPAFII	viability after 35 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	-1.1146879943538663	[40]	[2,16,NaN]	-6	hSpCas9	negative selection	9979906
39176693	39176716	19	-	27869803	HPAFII	viability after 35 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-1.2810811692289052	[235]	[19,81,NaN]	-6	hSpCas9	negative selection	9979907
39169546	39169569	19	+	27869803	HPAFII	viability after 31 days	CCGGCACCATGTTTGGGAAGAGG	PAK4	ENSG00000130669	-1.0603772947376364	[882]	[284,185,NaN]	-6	hSpCas9	negative selection	10062351
39173249	39173272	19	-	27869803	HPAFII	viability after 31 days	GCCGACATCAGGCCCGGAGAGGG	PAK4	ENSG00000130669	1.11203464453698	[240]	[221,368,NaN]	7	hSpCas9	negative selection	10062352
39173596	39173619	19	+	27869803	HPAFII	viability after 31 days	CCCTAACGGGCCATCAGCGGGGG	PAK4	ENSG00000130669	-0.5231064541607547	[162]	[55,71,NaN]	-3	hSpCas9	negative selection	10062353
39175043	39175066	19	+	27869803	HPAFII	viability after 31 days	CCGACATCGTCACCCACACCAGG	PAK4	ENSG00000130669	-0.3062266910605036	[646]	[341,240,NaN]	-2	hSpCas9	negative selection	10062354
39175374	39175397	19	+	27869803	HPAFII	viability after 31 days	ACGCCCAGGGCGTCATCCACCGG	PAK4	ENSG00000130669	-0.8229486149109544	[40]	[1,24,NaN]	-5	hSpCas9	negative selection	10062355
39176693	39176716	19	-	27869803	HPAFII	viability after 31 days	CTCTGGCCCGTAGGGAAGGCGGG	PAK4	ENSG00000130669	-1.0782210475050085	[235]	[11,117,NaN]	-6	hSpCas9	negative selection	10062356
39173748	39173771	19	-	28162770	P31FUJ	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-2.6922338230516756	[54]	[9]	-9	hSpCas9	negative selection	10206462
39173904	39173927	19	-	28162770	P31FUJ	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.5211793667674289	[117]	[198]	6	hSpCas9	negative selection	10206463
39173862	39173885	19	-	28162770	P31FUJ	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	1.7011679252504242	[94]	[362]	9	hSpCas9	negative selection	10206464
39173967	39173990	19	+	28162770	P31FUJ	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	0.6403677733501388	[100]	[184]	7	hSpCas9	negative selection	10206465
39177728	39177751	19	-	28162770	P31FUJ	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	-0.3068027858581557	[39]	[37]	-3	hSpCas9	negative selection	10206466
39169559	39169582	19	+	28162770	P31FUJ	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-1.721088685723861	[100]	[35]	-8	hSpCas9	negative selection	10206467
39169588	39169611	19	-	28162770	P31FUJ	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	0.08108857140756531	[143]	[178]	0	hSpCas9	negative selection	10206468
39169664	39169687	19	+	28162770	P31FUJ	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	0.2741577843055043	[18]	[26]	3	hSpCas9	negative selection	10206469
39169708	39169731	19	-	28162770	P31FUJ	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	0.005357532780385824	[233]	[275]	0	hSpCas9	negative selection	10206470
39169726	39169749	19	+	28162770	P31FUJ	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.32752041128936726	[747]	[1102]	3	hSpCas9	negative selection	10206471
39173748	39173771	19	-	28162770	TF1	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10375828
39173904	39173927	19	-	28162770	TF1	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	NaN	[NaN]	[107]	1	hSpCas9	negative selection	10375829
39173862	39173885	19	-	28162770	TF1	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	NaN	[NaN]	[207]	1	hSpCas9	negative selection	10375830
39173967	39173990	19	+	28162770	TF1	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	NaN	[NaN]	[66]	1	hSpCas9	negative selection	10375831
39177728	39177751	19	-	28162770	TF1	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	NaN	[NaN]	[141]	1	hSpCas9	negative selection	10375832
39169559	39169582	19	+	28162770	TF1	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10375833
39169588	39169611	19	-	28162770	TF1	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	NaN	[NaN]	[92]	1	hSpCas9	negative selection	10375834
39169664	39169687	19	+	28162770	TF1	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10375835
39169708	39169731	19	-	28162770	TF1	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10375836
39169726	39169749	19	+	28162770	TF1	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	NaN	[NaN]	[989]	1	hSpCas9	negative selection	10375837
39173748	39173771	19	-	28162770	SKM1	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-0.8960022794657825	[19]	[18]	-6	hSpCas9	negative selection	10545194
39173904	39173927	19	-	28162770	SKM1	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.880895387075574	[49]	[47]	-6	hSpCas9	negative selection	10545195
39173862	39173885	19	-	28162770	SKM1	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	0.261414310165632	[41]	[88]	2	hSpCas9	negative selection	10545196
39173967	39173990	19	+	28162770	SKM1	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	-0.7418313493380221	[34]	[36]	-5	hSpCas9	negative selection	10545197
39177728	39177751	19	-	28162770	SKM1	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	-1.2370391973008494	[19]	[14]	-7	hSpCas9	negative selection	10545198
39169559	39169582	19	+	28162770	SKM1	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-0.8626436825193514	[35]	[34]	-6	hSpCas9	negative selection	10545199
39169588	39169611	19	-	28162770	SKM1	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	0.09553614178602143	[35]	[67]	0	hSpCas9	negative selection	10545200
39169664	39169687	19	+	28162770	SKM1	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	-0.2914869813232257	[8]	[12]	-2	hSpCas9	negative selection	10545201
39169708	39169731	19	-	28162770	SKM1	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	-0.13919187390270482	[75]	[121]	-1	hSpCas9	negative selection	10545202
39169726	39169749	19	+	28162770	SKM1	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.4639938562550996	[186]	[455]	4	hSpCas9	negative selection	10545203
39173748	39173771	19	-	28162770	SKM1	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-0.8960022794657825	[19]	[18]	-6	hSpCas9	negative selection	10714560
39173904	39173927	19	-	28162770	SKM1	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.880895387075574	[49]	[47]	-6	hSpCas9	negative selection	10714561
39173862	39173885	19	-	28162770	SKM1	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	0.261414310165632	[41]	[88]	2	hSpCas9	negative selection	10714562
39173967	39173990	19	+	28162770	SKM1	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	-0.7418313493380221	[34]	[36]	-5	hSpCas9	negative selection	10714563
39177728	39177751	19	-	28162770	SKM1	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	-1.2370391973008494	[19]	[14]	-7	hSpCas9	negative selection	10714564
39169559	39169582	19	+	28162770	SKM1	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-0.8626436825193514	[35]	[34]	-6	hSpCas9	negative selection	10714565
39169588	39169611	19	-	28162770	SKM1	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	0.09553614178602143	[35]	[67]	0	hSpCas9	negative selection	10714566
39169664	39169687	19	+	28162770	SKM1	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	-0.2914869813232257	[8]	[12]	-2	hSpCas9	negative selection	10714567
39169708	39169731	19	-	28162770	SKM1	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	-0.13919187390270482	[75]	[121]	-1	hSpCas9	negative selection	10714568
39169726	39169749	19	+	28162770	SKM1	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.4639938562550996	[186]	[455]	4	hSpCas9	negative selection	10714569
39173748	39173771	19	-	28162770	PL21	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	0.36614956592824915	[122]	[68]	3	hSpCas9	negative selection	10883926
39173904	39173927	19	-	28162770	PL21	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	1.0332423057445759	[118]	[105]	8	hSpCas9	negative selection	10883927
39173862	39173885	19	-	28162770	PL21	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	0.9005793326304123	[127]	[103]	7	hSpCas9	negative selection	10883928
39173967	39173990	19	+	28162770	PL21	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	1.2876024557396595	[95]	[101]	9	hSpCas9	negative selection	10883929
39177728	39177751	19	-	28162770	PL21	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	2.3927846924317158	[48]	[111]	9	hSpCas9	negative selection	10883930
39169559	39169582	19	+	28162770	PL21	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	0.011935879328698884	[138]	[60]	0	hSpCas9	negative selection	10883931
39169588	39169611	19	-	28162770	PL21	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	0.20013961448932022	[119]	[59]	1	hSpCas9	negative selection	10883932
39169664	39169687	19	+	28162770	PL21	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	0.20013961448931994	[15]	[7]	1	hSpCas9	negative selection	10883933
39169708	39169731	19	-	28162770	PL21	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	0.7249811227729055	[195]	[140]	6	hSpCas9	negative selection	10883934
39169726	39169749	19	+	28162770	PL21	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	-0.021567929055538393	[701]	[300]	0	hSpCas9	negative selection	10883935
39173748	39173771	19	-	28162770	P31FUJ	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-2.6922338230516756	[54]	[9]	-9	hSpCas9	negative selection	11053292
39173904	39173927	19	-	28162770	P31FUJ	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	0.5211793667674289	[117]	[198]	6	hSpCas9	negative selection	11053293
39173862	39173885	19	-	28162770	P31FUJ	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	1.7011679252504242	[94]	[362]	9	hSpCas9	negative selection	11053294
39173967	39173990	19	+	28162770	P31FUJ	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	0.6403677733501388	[100]	[184]	7	hSpCas9	negative selection	11053295
39177728	39177751	19	-	28162770	P31FUJ	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	-0.3068027858581557	[39]	[37]	-3	hSpCas9	negative selection	11053296
39169559	39169582	19	+	28162770	P31FUJ	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-1.721088685723861	[100]	[35]	-8	hSpCas9	negative selection	11053297
39169588	39169611	19	-	28162770	P31FUJ	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	0.08108857140756531	[143]	[178]	0	hSpCas9	negative selection	11053298
39169664	39169687	19	+	28162770	P31FUJ	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	0.2741577843055043	[18]	[26]	3	hSpCas9	negative selection	11053299
39169708	39169731	19	-	28162770	P31FUJ	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	0.005357532780385824	[233]	[275]	0	hSpCas9	negative selection	11053300
39169726	39169749	19	+	28162770	P31FUJ	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.32752041128936726	[747]	[1102]	3	hSpCas9	negative selection	11053301
39173748	39173771	19	-	28162770	OCIAML5	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-5.606954073027465	[26]	[0]	-9	hSpCas9	negative selection	11222658
39173904	39173927	19	-	28162770	OCIAML5	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	1.0383089379615047	[81]	[303]	8	hSpCas9	negative selection	11222659
39173862	39173885	19	-	28162770	OCIAML5	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	0.678448145834783	[80]	[233]	6	hSpCas9	negative selection	11222660
39173967	39173990	19	+	28162770	OCIAML5	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	0.06410183833253225	[61]	[116]	0	hSpCas9	negative selection	11222661
39177728	39177751	19	-	28162770	OCIAML5	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	-0.852066570863997	[32]	[32]	-5	hSpCas9	negative selection	11222662
39169559	39169582	19	+	28162770	OCIAML5	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	0.3902942667050471	[40]	[96]	3	hSpCas9	negative selection	11222663
39169588	39169611	19	-	28162770	OCIAML5	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	-0.1415731880589819	[98]	[161]	-1	hSpCas9	negative selection	11222664
39169664	39169687	19	+	28162770	OCIAML5	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	2.317858430578316	[1]	[17]	9	hSpCas9	negative selection	11222665
39169708	39169731	19	-	28162770	OCIAML5	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	0.5779212698808183	[107]	[290]	5	hSpCas9	negative selection	11222666
39169726	39169749	19	+	28162770	OCIAML5	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.9277588330493736	[324]	[1115]	7	hSpCas9	negative selection	11222667
39173748	39173771	19	-	28162770	EOL1	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-1.6499223553329792	[136]	[22]	-8	hSpCas9	negative selection	11392024
39173904	39173927	19	-	28162770	EOL1	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.2860192143691236	[161]	[69]	-2	hSpCas9	negative selection	11392025
39173862	39173885	19	-	28162770	EOL1	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	0.7643905463770432	[275]	[246]	6	hSpCas9	negative selection	11392026
39173967	39173990	19	+	28162770	EOL1	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	1.3083343368649387	[209]	[273]	9	hSpCas9	negative selection	11392027
39177728	39177751	19	-	28162770	EOL1	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	1.0314629754870466	[103]	[111]	8	hSpCas9	negative selection	11392028
39169559	39169582	19	+	28162770	EOL1	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-1.3821135666635171	[187]	[37]	-7	hSpCas9	negative selection	11392029
39169588	39169611	19	-	28162770	EOL1	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	0.29341508941645233	[126]	[81]	2	hSpCas9	negative selection	11392030
39169664	39169687	19	+	28162770	EOL1	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	-2.8828071504870696	[13]	[0]	-9	hSpCas9	negative selection	11392031
39169708	39169731	19	-	28162770	EOL1	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	0.49299518550867416	[204]	[151]	4	hSpCas9	negative selection	11392032
39169726	39169749	19	+	28162770	EOL1	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.128838386531672	[801]	[461]	1	hSpCas9	negative selection	11392033
39173748	39173771	19	-	28162770	MOLM13	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-1.7126828640972422	[67]	[14]	-7	hSpCas9	negative selection	11561390
39173904	39173927	19	-	28162770	MOLM13	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	1.042867793693113	[144]	[215]	7	hSpCas9	negative selection	11561391
39173862	39173885	19	-	28162770	MOLM13	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	0.45401720696302145	[208]	[206]	3	hSpCas9	negative selection	11561392
39173967	39173990	19	+	28162770	MOLM13	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	0.44619431044525987	[200]	[197]	3	hSpCas9	negative selection	11561393
39177728	39177751	19	-	28162770	MOLM13	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	1.9518219620344903	[68]	[192]	9	hSpCas9	negative selection	11561394
39169559	39169582	19	+	28162770	MOLM13	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-4.297645364818399	[135]	[4]	-9	hSpCas9	negative selection	11561395
39169588	39169611	19	-	28162770	MOLM13	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	-1.503351625473997	[148]	[37]	-6	hSpCas9	negative selection	11561396
39169664	39169687	19	+	28162770	MOLM13	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	0.3303858577946439	[21]	[19]	2	hSpCas9	negative selection	11561397
39169708	39169731	19	-	28162770	MOLM13	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	0.23144918572249817	[257]	[218]	1	hSpCas9	negative selection	11561398
39169726	39169749	19	+	28162770	MOLM13	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	-0.6646210330347995	[922]	[420]	-4	hSpCas9	negative selection	11561399
39173748	39173771	19	-	28162770	HEL	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-2.8166927866369402	[109]	[9]	-8	hSpCas9	negative selection	11730756
39173904	39173927	19	-	28162770	HEL	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.23352579957739839	[133]	[72]	-2	hSpCas9	negative selection	11730757
39173862	39173885	19	-	28162770	HEL	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	1.2310140667623488	[144]	[217]	9	hSpCas9	negative selection	11730758
39173967	39173990	19	+	28162770	HEL	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	-0.24622985561089927	[99]	[53]	-2	hSpCas9	negative selection	11730759
39177728	39177751	19	-	28162770	HEL	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	-0.14945628288624135	[70]	[40]	-1	hSpCas9	negative selection	11730760
39169559	39169582	19	+	28162770	HEL	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-0.3917495443849336	[126]	[61]	-3	hSpCas9	negative selection	11730761
39169588	39169611	19	-	28162770	HEL	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	-0.3273079458980154	[142]	[72]	-2	hSpCas9	negative selection	11730762
39169664	39169687	19	+	28162770	HEL	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	-0.8597615085288264	[16]	[5]	-5	hSpCas9	negative selection	11730763
39169708	39169731	19	-	28162770	HEL	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	0.13318373393722344	[204]	[143]	1	hSpCas9	negative selection	11730764
39169726	39169749	19	+	28162770	HEL	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	-0.1298506718965704	[778]	[455]	-1	hSpCas9	negative selection	11730765
39173748	39173771	19	-	28162770	MV411	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-1.9505018268291334	[77]	[16]	-8	hSpCas9	negative selection	11900122
39173904	39173927	19	-	28162770	MV411	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.4934752279000937	[121]	[72]	-4	hSpCas9	negative selection	11900123
39173862	39173885	19	-	28162770	MV411	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	-0.651633540366444	[137]	[73]	-4	hSpCas9	negative selection	11900124
39173967	39173990	19	+	28162770	MV411	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	0.03513394706991124	[94]	[81]	0	hSpCas9	negative selection	11900125
39177728	39177751	19	-	28162770	MV411	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	-0.20775707496805107	[84]	[61]	-1	hSpCas9	negative selection	11900126
39169559	39169582	19	+	28162770	MV411	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-2.324104434176059	[106]	[17]	-8	hSpCas9	negative selection	11900127
39169588	39169611	19	-	28162770	MV411	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	-0.11315216447369192	[103]	[80]	-1	hSpCas9	negative selection	11900128
39169664	39169687	19	+	28162770	MV411	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	-0.6005593557721749	[8]	[4]	-4	hSpCas9	negative selection	11900129
39169708	39169731	19	-	28162770	MV411	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	0.24743755078277535	[141]	[141]	2	hSpCas9	negative selection	11900130
39169726	39169749	19	+	28162770	MV411	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.017403718356850506	[630]	[537]	0	hSpCas9	negative selection	11900131
39173748	39173771	19	-	28162770	MONOMAC1	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	0.22519615362349432	[49]	[66]	2	hSpCas9	negative selection	12069488
39173904	39173927	19	-	28162770	MONOMAC1	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.798487470569279	[87]	[57]	-6	hSpCas9	negative selection	12069489
39173862	39173885	19	-	28162770	MONOMAC1	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	0.4074218292873998	[97]	[148]	4	hSpCas9	negative selection	12069490
39173967	39173990	19	+	28162770	MONOMAC1	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	0.6689458049687589	[61]	[112]	6	hSpCas9	negative selection	12069491
39177728	39177751	19	-	28162770	MONOMAC1	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	0.6462376492529933	[33]	[60]	6	hSpCas9	negative selection	12069492
39169559	39169582	19	+	28162770	MONOMAC1	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-1.3523150725374646	[97]	[43]	-7	hSpCas9	negative selection	12069493
39169588	39169611	19	-	28162770	MONOMAC1	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	1.506399123541458	[73]	[240]	9	hSpCas9	negative selection	12069494
39169664	39169687	19	+	28162770	MONOMAC1	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	1.317536325770205	[6]	[19]	9	hSpCas9	negative selection	12069495
39169708	39169731	19	-	28162770	MONOMAC1	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	-0.3583177540926146	[103]	[92]	-3	hSpCas9	negative selection	12069496
39169726	39169749	19	+	28162770	MONOMAC1	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.4063583717585877	[336]	[511]	4	hSpCas9	negative selection	12069497
39173748	39173771	19	-	28162770	OCIAML2	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-1.16577524371374	[16]	[41]	-6	hSpCas9	negative selection	12238854
39173904	39173927	19	-	28162770	OCIAML2	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	1.162695697040394	[21]	[272]	9	hSpCas9	negative selection	12238855
39173862	39173885	19	-	28162770	OCIAML2	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	-0.16946029052159628	[27]	[137]	-1	hSpCas9	negative selection	12238856
39173967	39173990	19	+	28162770	OCIAML2	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	0.42749056073862524	[21]	[163]	4	hSpCas9	negative selection	12238857
39177728	39177751	19	-	28162770	OCIAML2	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	1.4362607703663572	[7]	[119]	9	hSpCas9	negative selection	12238858
39169559	39169582	19	+	28162770	OCIAML2	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-0.9731301657713443	[16]	[47]	-6	hSpCas9	negative selection	12238859
39169588	39169611	19	-	28162770	OCIAML2	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	0.5379321882612629	[20]	[168]	5	hSpCas9	negative selection	12238860
39169664	39169687	19	+	28162770	OCIAML2	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	-1.6632749031845577	[3]	[6]	-7	hSpCas9	negative selection	12238861
39169708	39169731	19	-	28162770	OCIAML2	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	0.010496864494455298	[35]	[200]	0	hSpCas9	negative selection	12238862
39169726	39169749	19	+	28162770	OCIAML2	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.3893397229788649	[99]	[725]	4	hSpCas9	negative selection	12238863
39173748	39173771	19	-	28162770	OCIAML3	viability	GGGCCCAGGAACAGCAGGGGCGG	PAK4	ENSG00000130669	-1.272079545436801	[19]	[24]	-7	hSpCas9	negative selection	12408220
39173904	39173927	19	-	28162770	OCIAML3	viability	GGCGATGCACACGATGCCCGTGG	PAK4	ENSG00000130669	-0.35522078073704666	[24]	[58]	-3	hSpCas9	negative selection	12408221
39173862	39173885	19	-	28162770	OCIAML3	viability	GAAGTTGTCCAGGTAGGAGCGGG	PAK4	ENSG00000130669	-0.3834406543845048	[34]	[80]	-3	hSpCas9	negative selection	12408222
39173967	39173990	19	+	28162770	OCIAML3	viability	TGGACCTGCGCAAGCAGCAGAGG	PAK4	ENSG00000130669	0.5966759212849464	[22]	[104]	5	hSpCas9	negative selection	12408223
39177728	39177751	19	-	28162770	OCIAML3	viability	GGGGTGGCTCGTTGAAGTAGGGG	PAK4	ENSG00000130669	-0.5940076403241632	[17]	[35]	-4	hSpCas9	negative selection	12408224
39169559	39169582	19	+	28162770	OCIAML3	viability	TGGGAAGAGGAAGAAGCGGGTGG	PAK4	ENSG00000130669	-1.6517231381804505	[50]	[48]	-8	hSpCas9	negative selection	12408225
39169588	39169611	19	-	28162770	OCIAML3	viability	GTGCTCGAAGTTGGACGGCGCGG	PAK4	ENSG00000130669	0.8591649878414516	[20]	[114]	7	hSpCas9	negative selection	12408226
39169664	39169687	19	+	28162770	OCIAML3	viability	CCAGTGGCAGAGCCTGATCGAGG	PAK4	ENSG00000130669	-0.231437560939455	[6]	[17]	-2	hSpCas9	negative selection	12408227
39169708	39169731	19	-	28162770	OCIAML3	viability	GATGCAGGCGGGGTCGACGAGGG	PAK4	ENSG00000130669	0.3905623191062309	[46]	[185]	3	hSpCas9	negative selection	12408228
39169726	39169749	19	+	28162770	OCIAML3	viability	GCATCACCTCCATCCAGCCCGGG	PAK4	ENSG00000130669	0.03195783452236767	[184]	[570]	0	hSpCas9	negative selection	12408229