Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5216
• Symbol: PFN1
• Description: profilin 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PFN1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
4946811	4946834	17	-	26472758	Jiyoye	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-2.400179540551731	[90]	[12]	-8	hSpCas9	negative selection	119238
4946669	4946692	17	-	26472758	Jiyoye	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-2.8658431129005426	[144]	[14]	-9	hSpCas9	negative selection	119239
4946694	4946717	17	-	26472758	Jiyoye	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-1.1282050903647223	[428]	[147]	-6	hSpCas9	negative selection	119240
4946620	4946643	17	+	26472758	Jiyoye	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.3539700251554594	[721]	[212]	-7	hSpCas9	negative selection	119241
4946811	4946834	17	-	26472758	KBM7	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-4.9562980210227385	[340,347]	[9,0]	-9	hSpCas9	negative selection	310356
4946669	4946692	17	-	26472758	KBM7	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.4449747503640213	[481,333]	[78,60]	-7	hSpCas9	negative selection	310357
4946694	4946717	17	-	26472758	KBM7	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-1.2270072443241131	[1351,892]	[167,269]	-7	hSpCas9	negative selection	310358
4946620	4946643	17	+	26472758	KBM7	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.6981276479575373	[3140,3095]	[831,974]	-5	hSpCas9	negative selection	310359
4946811	4946834	17	-	26472758	Raji	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-1.647503966789869	[215]	[15]	-8	hSpCas9	negative selection	501474
4946669	4946692	17	-	26472758	Raji	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	0.2814129351486486	[155]	[43]	2	hSpCas9	negative selection	501475
4946694	4946717	17	-	26472758	Raji	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-0.5727361983878967	[704]	[109]	-4	hSpCas9	negative selection	501476
4946620	4946643	17	+	26472758	Raji	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	0.3355324235635351	[1464]	[428]	3	hSpCas9	negative selection	501477
4946811	4946834	17	-	26472758	K562	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-5.895132624732347	[281]	[3]	-9	hSpCas9	negative selection	692592
4946669	4946692	17	-	26472758	K562	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-3.5588083087684805	[348]	[24]	-8	hSpCas9	negative selection	692593
4946694	4946717	17	-	26472758	K562	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-2.5273708344074413	[1201]	[175]	-8	hSpCas9	negative selection	692594
4946620	4946643	17	+	26472758	K562	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.7723895600201072	[2071]	[511]	-7	hSpCas9	negative selection	692595
4946669	4946692	17	-	26627737	DLD1	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-2.110139095659963	[505]	[22,70,19]	-9	hSpCas9	negative selection	798721
4946672	4946695	17	-	26627737	DLD1	viability	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-2.1050038968727143	[279]	[5,7,42]	-9	hSpCas9	negative selection	798722
4946669	4946692	17	-	26627737	GBM cells	viability after 5 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	0.0803607462232176	[290]	[152,176]	1	hSpCas9	negative selection	881036
4946672	4946695	17	-	26627737	GBM cells	viability after 5 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-1.6635060571843825	[126]	[20,21]	-9	hSpCas9	negative selection	881037
4946669	4946692	17	-	26627737	GBM cells	viability after 13 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.3222125819873509	[290]	[149,106]	-4	hSpCas9	negative selection	963351
4946672	4946695	17	-	26627737	GBM cells	viability after 13 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-0.4358211897173325	[126]	[72,32]	-5	hSpCas9	negative selection	963352
4946669	4946692	17	-	26627737	GBM cells	viability after 21 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.0964889887394339	[290]	[150,144]	-1	hSpCas9	negative selection	1045666
4946672	4946695	17	-	26627737	GBM cells	viability after 21 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-0.6194508771064469	[126]	[46,42]	-5	hSpCas9	negative selection	1045667
4946669	4946692	17	-	26627737	RPE1	viability after 9 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.7587016885593947	[1237]	[100,131]	-8	hSpCas9	negative selection	1127981
4946672	4946695	17	-	26627737	RPE1	viability after 9 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-1.108695242059859	[243]	[27,44]	-7	hSpCas9	negative selection	1127982
4946669	4946692	17	-	26627737	RPE1	viability after 12 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-2.7833062600761096	[1237]	[58,36]	-9	hSpCas9	negative selection	1210296
4946672	4946695	17	-	26627737	RPE1	viability after 12 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-3.0501667767855265	[243]	[4,10]	-9	hSpCas9	negative selection	1210297
4946669	4946692	17	-	26627737	RPE1	viability after 15 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.82609000362991	[1237]	[139,58]	-8	hSpCas9	negative selection	1292611
4946672	4946695	17	-	26627737	RPE1	viability after 15 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-0.6252091563394206	[243]	[86,3]	-4	hSpCas9	negative selection	1292612
4946669	4946692	17	-	26627737	RPE1	viability after 18 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-4.1707984871939034	[1237]	[19,16]	-9	hSpCas9	negative selection	1374926
4946672	4946695	17	-	26627737	RPE1	viability after 18 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-2.750941010746075	[243]	[17,0]	-9	hSpCas9	negative selection	1374927
4946669	4946692	17	-	26627737	HeLa	viability after 8 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	0.2068333338066674	[281]	[164,137,127]	2	hSpCas9	negative selection	1457241
4946672	4946695	17	-	26627737	HeLa	viability after 8 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-1.247329685401913	[119]	[59,1,12]	-8	hSpCas9	negative selection	1457242
4946669	4946692	17	-	26627737	HeLa	viability after 12 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	0.403988255328529	[281]	[176,118,170]	3	hSpCas9	negative selection	1539556
4946672	4946695	17	-	26627737	HeLa	viability after 12 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-2.064675131089711	[119]	[28,2,4]	-9	hSpCas9	negative selection	1539557
4946669	4946692	17	-	26627737	HeLa	viability after 15 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.05900906322862265	[281]	[150,93,82]	0	hSpCas9	negative selection	1621871
4946672	4946695	17	-	26627737	HeLa	viability after 15 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-0.9890625665173476	[119]	[0,13,61]	-7	hSpCas9	negative selection	1621872
4946669	4946692	17	-	26627737	HeLa	viability after 18 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.0508458404243598	[281]	[103,75,82]	0	hSpCas9	negative selection	1704186
4946672	4946695	17	-	26627737	HeLa	viability after 18 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-0.9458648163057031	[119]	[0,12,61]	-7	hSpCas9	negative selection	1704187
4946669	4946692	17	-	26627737	HCT116	viability after 6 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	0.5616417114892165	[646]	[211,115]	3	hSpCas9	negative selection	1786501
4946672	4946695	17	-	26627737	HCT116	viability after 6 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-4.231817597625853	[161]	[1,0]	-9	hSpCas9	negative selection	1786502
4946669	4946692	17	-	26627737	HCT116	viability after 8 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	0.5487724878128069	[321]	[254,298,224]	5	hSpCas9	negative selection	1868816
4946672	4946695	17	-	26627737	HCT116	viability after 8 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-0.25589186424904575	[136]	[72,66,49]	-3	hSpCas9	negative selection	1868817
4946669	4946692	17	-	26627737	HCT116	viability after 9 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	1.0136315917843846	[646]	[240,433]	7	hSpCas9	negative selection	1951131
4946672	4946695	17	-	26627737	HCT116	viability after 9 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	0.7670208788061121	[161]	[0,130]	5	hSpCas9	negative selection	1951132
4946669	4946692	17	-	26627737	HCT116	viability after 12 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	0.26779952444853594	[321]	[183,164,262]	2	hSpCas9	negative selection	2033446
4946672	4946695	17	-	26627737	HCT116	viability after 12 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-0.518566352557323	[136]	[85,23,36]	-5	hSpCas9	negative selection	2033447
4946669	4946692	17	-	26627737	HCT116	viability after 15 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	0.323845488253653	[321]	[243,227,223]	3	hSpCas9	negative selection	2115761
4946672	4946695	17	-	26627737	HCT116	viability after 15 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-0.3191714211687513	[136]	[107,51,34]	-3	hSpCas9	negative selection	2115762
4946669	4946692	17	-	26627737	HCT116	viability after 18 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	0.6693288737755327	[321]	[183,176,392]	5	hSpCas9	negative selection	2198076
4946672	4946695	17	-	26627737	HCT116	viability after 18 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-0.443551079827083	[136]	[20,60,63]	-4	hSpCas9	negative selection	2198077
4945979	4946002	17	-	24336569	HL60	viability	CCAGCGCTAGTCCTGCTGATGGG	PFN1	ENSG00000108518	0.4490506160698835	[242]	[701]	4	hSpCas9	negative selection	2283643
4946620	4946643	17	+	24336569	HL60	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.3735654937767487	[370]	[605]	-3	hSpCas9	negative selection	2283644
4946668	4946691	17	-	24336569	HL60	viability	TTCGTACCAAGAGCACCGGTGGG	PFN1	ENSG00000108518	-1.466940851317276	[788]	[603]	-8	hSpCas9	negative selection	2283645
4946799	4946822	17	-	24336569	HL60	viability	GCCAGCTGAGGTGGGTGTCCTGG	PFN1	ENSG00000108518	-1.4851862866799062	[253]	[191]	-8	hSpCas9	negative selection	2283646
4946807	4946830	17	-	24336569	HL60	viability	CTCTTCCAGCCAGCTGAGGTGGG	PFN1	ENSG00000108518	-2.243164334809478	[480]	[214]	-9	hSpCas9	negative selection	2283647
4945979	4946002	17	-	24336569	KBM7	viability	CCAGCGCTAGTCCTGCTGATGGG	PFN1	ENSG00000108518	-1.530405627678503	[232]	[219]	-7	hSpCas9	negative selection	2350820
4946620	4946643	17	+	24336569	KBM7	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.7654942289296214	[358]	[287]	-8	hSpCas9	negative selection	2350821
4946668	4946691	17	-	24336569	KBM7	viability	TTCGTACCAAGAGCACCGGTGGG	PFN1	ENSG00000108518	-0.9027448085330361	[400]	[584]	-6	hSpCas9	negative selection	2350822
4946799	4946822	17	-	24336569	KBM7	viability	GCCAGCTGAGGTGGGTGTCCTGG	PFN1	ENSG00000108518	-2.6511125906340145	[303]	[131]	-9	hSpCas9	negative selection	2350823
4946807	4946830	17	-	24336569	KBM7	viability	CTCTTCCAGCCAGCTGAGGTGGG	PFN1	ENSG00000108518	-3.3150551110440576	[342]	[93]	-9	hSpCas9	negative selection	2350824
4946669	4946692		-	24336571	A375	resistance to PLX after 7 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	0.1940448952999112	[2,3]	[4,2]	6	hSpCas9	positive selection	3135092
4945980	4946003		-	24336571	A375	resistance to PLX after 7 days	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	0.06301469248775482	[15,18]	[17,17]	2	hSpCas9	positive selection	3135093
4946669	4946692		-	24336571	A375	resistance to PLX after 14 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	0.854818620930518	[1,1]	[1,1]	7	hSpCas9	positive selection	3192885
4945980	4946003		-	24336571	A375	resistance to PLX after 14 days	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.42753304010874715	[11,11]	[3,2]	-5	hSpCas9	positive selection	3192886
4946669	4946692		-	24336571	A375	viability after 7 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.8878632686052305	[6]	[2,3]	-8	hSpCas9	negative selection	3250678
4945980	4946003		-	24336571	A375	viability after 7 days	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.21520937529210182	[21]	[15,18]	-3	hSpCas9	negative selection	3250679
4946669	4946692		-	24336571	A375	viability after 14 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.4858691447416206	[6]	[1,1]	-9	hSpCas9	negative selection	3308471
4945980	4946003		-	24336571	A375	viability after 14 days	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.7258600002706243	[21]	[11,11]	-7	hSpCas9	negative selection	3308472
4946669	4946692	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	0.18051061439500407	[134,134]	[0,0]	1	hSpCas9	positive selection	3385471
4946620	4946643	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.323874370479122	[382,382]	[0,0]	-8	hSpCas9	positive selection	3385472
4945899	4945922	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	1.1912370209880627	[66,66]	[0,0]	5	hSpCas9	positive selection	3385473
4946669	4946692	17	-	26780180	A375	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	1.99523230435733	[]	[]	9	hSpCas9	negative selection	3980115
4946620	4946643	17	+	26780180	A375	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	1.6260468267059	[]	[]	8	hSpCas9	negative selection	3980116
4945899	4945922	17	+	26780180	A375	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	1.57983612145768	[]	[]	8	hSpCas9	negative selection	3980117
4945980	4946003	17	-	26780180	A375	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	2.85173871312152	[]	[]	9	hSpCas9	negative selection	3980118
4946669	4946692	17	-	26780180	HT29	viability (GeCKOv2 library)	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	2.19292850443224	[]	[]	9	hSpCas9	negative selection	4088081
4946620	4946643	17	+	26780180	HT29	viability (GeCKOv2 library)	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	1.350487455842	[]	[]	7	hSpCas9	negative selection	4088082
4945899	4945922	17	+	26780180	HT29	viability (GeCKOv2 library)	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	2.15721566040947	[]	[]	9	hSpCas9	negative selection	4088083
4945980	4946003	17	-	26780180	HT29	viability (GeCKOv2 library)	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	1.46339469139596	[]	[]	7	hSpCas9	negative selection	4088084
4946669	4946692	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.7705675888027097	[2]	[0,0]	-9	hSpCas9	positive selection	4160008
4945980	4946003	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.39191057256810297	[4]	[2,1]	-7	hSpCas9	positive selection	4160009
4946669	4946692	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.12307264283638086	[2]	[0,2,0,0]	-2	hSpCas9	positive selection	4224030
4945980	4946003	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.00500560894876928	[3]	[0,1,4,0]	0	hSpCas9	positive selection	4224031
4945980	4946003	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.3906949584506742	[4]	[2,1]	-7	hSpCas9	positive selection	4289825
4946669	4946692	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	0.1964485907086887	[3]	[3,2]	4	hSpCas9	positive selection	4354075
4946620	4946643	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	0.049784616386190306	[4]	[4,2]	1	hSpCas9	positive selection	4354076
4945899	4945922	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.5627401722316256	[2]	[0,1]	-8	hSpCas9	positive selection	4354077
4946667	4946689	17	-	27760321	OCIAML3	viability	CGTACCAAGAGCACCGGTGGGG	PFN1	ENSG00000108518	-1.3685005413226063	[693,628]	[171,236]	-8	hSpCas9	negative selection	4427161
4946727	4946749	17	-	27760321	OCIAML3	viability	CAGAAATGTTCGGTGATCCGGG	PFN1	ENSG00000108518	-1.020919623153744	[475,409]	[138,210]	-7	hSpCas9	negative selection	4427162
4946767	4946789	17	+	27760321	OCIAML3	viability	ATTCACGTAAAAACTTGACCGG	PFN1	ENSG00000108518	-2.8407409709003697	[42,38]	[0,8]	-9	hSpCas9	negative selection	4427163
4946667	4946689	17	-	27760321	OCIAML2	viability	CGTACCAAGAGCACCGGTGGGG	PFN1	ENSG00000108518	-1.5676195063010825	[693,628]	[163,201]	-8	hSpCas9	negative selection	4510624
4946727	4946749	17	-	27760321	OCIAML2	viability	CAGAAATGTTCGGTGATCCGGG	PFN1	ENSG00000108518	-1.077119241417146	[475,409]	[155,186]	-7	hSpCas9	negative selection	4510625
4946767	4946789	17	+	27760321	OCIAML2	viability	ATTCACGTAAAAACTTGACCGG	PFN1	ENSG00000108518	-0.04021978274444571	[42,38]	[39,21]	0	hSpCas9	negative selection	4510626
4946667	4946689	17	-	27760321	MV411	viability	CGTACCAAGAGCACCGGTGGGG	PFN1	ENSG00000108518	-1.396322847617209	[693,628]	[56,328]	-7	hSpCas9	negative selection	4594087
4946727	4946749	17	-	27760321	MV411	viability	CAGAAATGTTCGGTGATCCGGG	PFN1	ENSG00000108518	-1.3804882798335494	[475,409]	[69,174]	-7	hSpCas9	negative selection	4594088
4946767	4946789	17	+	27760321	MV411	viability	ATTCACGTAAAAACTTGACCGG	PFN1	ENSG00000108518	-4.7568339977539456	[42,38]	[0,0]	-9	hSpCas9	negative selection	4594089
4946667	4946689	17	-	27760321	HL60	viability	CGTACCAAGAGCACCGGTGGGG	PFN1	ENSG00000108518	-1.855151201486545	[693,628]	[173,122]	-9	hSpCas9	negative selection	4677550
4946727	4946749	17	-	27760321	HL60	viability	CAGAAATGTTCGGTGATCCGGG	PFN1	ENSG00000108518	-2.753402858933421	[475,409]	[53,52]	-9	hSpCas9	negative selection	4677551
4946767	4946789	17	+	27760321	HL60	viability	ATTCACGTAAAAACTTGACCGG	PFN1	ENSG00000108518	1.6559086036788428	[42,38]	[37,176]	9	hSpCas9	negative selection	4677552
4946667	4946689	17	-	27760321	HT1080	viability	CGTACCAAGAGCACCGGTGGGG	PFN1	ENSG00000108518	-1.3414793132134264	[628,490]	[151,17]	-5	hSpCas9	negative selection	4761013
4946727	4946749	17	-	27760321	HT1080	viability	CAGAAATGTTCGGTGATCCGGG	PFN1	ENSG00000108518	-1.259725904702812	[409,319]	[75,43]	-5	hSpCas9	negative selection	4761014
4946767	4946789	17	+	27760321	HT1080	viability	ATTCACGTAAAAACTTGACCGG	PFN1	ENSG00000108518	-3.8031003095098503	[38,30]	[0,0]	-8	hSpCas9	negative selection	4761015
4946667	4946689	17	-	27760321	HT29	viability after 7 days	CGTACCAAGAGCACCGGTGGGG	PFN1	ENSG00000108518	0.037563024569470915	[628,490]	[1128,767,385]	0	hSpCas9	negative selection	4844476
4946727	4946749	17	-	27760321	HT29	viability after 7 days	CAGAAATGTTCGGTGATCCGGG	PFN1	ENSG00000108518	-0.1545037183158144	[409,319]	[427,409,426]	-2	hSpCas9	negative selection	4844477
4946767	4946789	17	+	27760321	HT29	viability after 7 days	ATTCACGTAAAAACTTGACCGG	PFN1	ENSG00000108518	0.39322937682878134	[38,30]	[83,70,26]	6	hSpCas9	negative selection	4844478
4946667	4946689	17	-	27760321	HT29	viability after 25 days	CGTACCAAGAGCACCGGTGGGG	PFN1	ENSG00000108518	-0.8945974778779084	[628,490]	[276,332,435]	-6	hSpCas9	negative selection	4927939
4946727	4946749	17	-	27760321	HT29	viability after 25 days	CAGAAATGTTCGGTGATCCGGG	PFN1	ENSG00000108518	-0.7235189900065229	[409,319]	[238,329,181]	-6	hSpCas9	negative selection	4927940
4946767	4946789	17	+	27760321	HT29	viability after 25 days	ATTCACGTAAAAACTTGACCGG	PFN1	ENSG00000108518	-1.0085863975125413	[38,30]	[0,12,49]	-6	hSpCas9	negative selection	4927941
4946667	4946689	17	-	27760321	HT29	viability after 22 days	CGTACCAAGAGCACCGGTGGGG	PFN1	ENSG00000108518	-0.20095632503578437	[628,490]	[703,608,370]	-2	hSpCas9	negative selection	5011402
4946727	4946749	17	-	27760321	HT29	viability after 22 days	CAGAAATGTTCGGTGATCCGGG	PFN1	ENSG00000108518	-1.0099612598548406	[409,319]	[140,219,269]	-6	hSpCas9	negative selection	5011403
4946767	4946789	17	+	27760321	HT29	viability after 22 days	ATTCACGTAAAAACTTGACCGG	PFN1	ENSG00000108518	-3.0268585581407743	[38,30]	[1,6,5]	-8	hSpCas9	negative selection	5011404
4946667	4946689	17	-	27760321	HT29	viability after 19 days	CGTACCAAGAGCACCGGTGGGG	PFN1	ENSG00000108518	-0.6239280604249027	[628,490]	[457,324,465]	-5	hSpCas9	negative selection	5094865
4946727	4946749	17	-	27760321	HT29	viability after 19 days	CAGAAATGTTCGGTGATCCGGG	PFN1	ENSG00000108518	-0.9740958817060786	[409,319]	[166,370,98]	-6	hSpCas9	negative selection	5094866
4946767	4946789	17	+	27760321	HT29	viability after 19 days	ATTCACGTAAAAACTTGACCGG	PFN1	ENSG00000108518	-1.882260070388229	[38,30]	[10,20,0]	-8	hSpCas9	negative selection	5094867
4946667	4946689	17	-	27760321	HT29	viability after 16 days	CGTACCAAGAGCACCGGTGGGG	PFN1	ENSG00000108518	-0.2597905473249587	[628,490]	[547,412,613]	-3	hSpCas9	negative selection	5178328
4946727	4946749	17	-	27760321	HT29	viability after 16 days	CAGAAATGTTCGGTGATCCGGG	PFN1	ENSG00000108518	-0.805274177194111	[409,319]	[259,214,228]	-6	hSpCas9	negative selection	5178329
4946767	4946789	17	+	27760321	HT29	viability after 16 days	ATTCACGTAAAAACTTGACCGG	PFN1	ENSG00000108518	-0.41564208801125524	[38,30]	[19,39,26]	-4	hSpCas9	negative selection	5178330
4946667	4946689	17	-	27760321	HT29	viability after 13 days	CGTACCAAGAGCACCGGTGGGG	PFN1	ENSG00000108518	-0.30011561917517077	[628,490]	[480,591,510]	-4	hSpCas9	negative selection	5261791
4946727	4946749	17	-	27760321	HT29	viability after 13 days	CAGAAATGTTCGGTGATCCGGG	PFN1	ENSG00000108518	-0.43766959105779757	[409,319]	[288,388,262]	-5	hSpCas9	negative selection	5261792
4946767	4946789	17	+	27760321	HT29	viability after 13 days	ATTCACGTAAAAACTTGACCGG	PFN1	ENSG00000108518	-1.6031209089257326	[38,30]	[3,2,31]	-8	hSpCas9	negative selection	5261793
4946667	4946689	17	-	27760321	HT29	viability after 10 days	CGTACCAAGAGCACCGGTGGGG	PFN1	ENSG00000108518	-0.12243420606672262	[628,490]	[746,578,599]	-2	hSpCas9	negative selection	5345254
4946727	4946749	17	-	27760321	HT29	viability after 10 days	CAGAAATGTTCGGTGATCCGGG	PFN1	ENSG00000108518	-0.49004015517916893	[409,319]	[303,305,361]	-6	hSpCas9	negative selection	5345255
4946767	4946789	17	+	27760321	HT29	viability after 10 days	ATTCACGTAAAAACTTGACCGG	PFN1	ENSG00000108518	0.22578444213669657	[38,30]	[16,76,59]	3	hSpCas9	negative selection	5345256
4946667	4946689	17	-	27760321	MOLM13	viability	CGTACCAAGAGCACCGGTGGGG	PFN1	ENSG00000108518	-1.2757123279533098	[693,628]	[119,182]	-6	hSpCas9	negative selection	5428717
4946727	4946749	17	-	27760321	MOLM13	viability	CAGAAATGTTCGGTGATCCGGG	PFN1	ENSG00000108518	-1.063140054001669	[475,409]	[54,173]	-6	hSpCas9	negative selection	5428718
4946767	4946789	17	+	27760321	MOLM13	viability	ATTCACGTAAAAACTTGACCGG	PFN1	ENSG00000108518	-4.53077718492635	[42,38]	[0,0]	-9	hSpCas9	negative selection	5428719
4948058	4948081	17	+	27661255	K562	viability	GGGATGGGCGCCGCCGCCTGGGG	PFN1	ENSG00000108518	0.19141649274348665	[977,1133]	[951,967]	6	dCas9-KRAB	negative selection	5501346
4945980	4946003	17	-	27260156	BXPC3	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.5395249905899098	[1105]	[743,757,750,949]	-8	hSpCas9	negative selection	5562285
4946669	4946692	17	-	27260156	BXPC3	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.658817910398374	[681]	[468,394,535,399]	-8	hSpCas9	negative selection	5626535
4946620	4946643	17	+	27260156	BXPC3	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.5672940487136262	[1127]	[771,824,734,852]	-8	hSpCas9	negative selection	5626536
4945899	4945922	17	+	27260156	BXPC3	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-1.4090421178517332	[331]	[137,117,101,167]	-9	hSpCas9	negative selection	5626537
4945980	4946003	17	-	27260156	A673	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.33107857748051195	[1105]	[1332,937,898,1088]	-7	hSpCas9	negative selection	5683536
4946669	4946692	17	-	27260156	A673	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.4490873711007795	[681]	[468,543,667,708]	-8	hSpCas9	negative selection	5747786
4946620	4946643	17	+	27260156	A673	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.5195839634633761	[1127]	[994,810,900,1087]	-8	hSpCas9	negative selection	5747787
4945899	4945922	17	+	27260156	A673	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.707148692169676	[331]	[275,252,206,243]	-9	hSpCas9	negative selection	5747788
4945980	4946003	17	-	27260156	A375	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.6575161205939174	[1105]	[633,986,1014,675]	-7	hSpCas9	negative selection	5804787
4946669	4946692	17	-	27260156	A375	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.6645387801462457	[681]	[492,576,468,481]	-7	hSpCas9	negative selection	5869037
4946620	4946643	17	+	27260156	A375	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.7253652664932027	[1127]	[774,745,903,756]	-7	hSpCas9	negative selection	5869038
4945899	4945922	17	+	27260156	A375	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-1.2889702295798702	[331]	[139,223,137,142]	-9	hSpCas9	negative selection	5869039
4945980	4946003	17	-	27260156	COLO741	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.06633373913930707	[1105]	[1675,1243,1166]	-1	hSpCas9	negative selection	5926038
4946669	4946692	17	-	27260156	COLO741	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.5014260432132166	[681]	[821,544,503]	-8	hSpCas9	negative selection	5990288
4946620	4946643	17	+	27260156	COLO741	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	0.04446717097370745	[1127]	[1581,1775,1132]	0	hSpCas9	negative selection	5990289
4945899	4945922	17	+	27260156	COLO741	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.38782837403250536	[331]	[381,288,306]	-7	hSpCas9	negative selection	5990290
4945980	4946003	17	-	27260156	CAL120	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.9438903447354628	[1105]	[828,668,665]	-8	hSpCas9	negative selection	6047289
4946669	4946692	17	-	27260156	CAL120	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.6774760211626285	[681]	[657,485,467]	-7	hSpCas9	negative selection	6111539
4946620	4946643	17	+	27260156	CAL120	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.7206882713413968	[1127]	[927,708,927]	-7	hSpCas9	negative selection	6111540
4945899	4945922	17	+	27260156	CAL120	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-2.1521397568047016	[331]	[65,73,133]	-9	hSpCas9	negative selection	6111541
4945980	4946003	17	-	27260156	CADOES1	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	0.38205078796994907	[1105]	[1279,932,1483,1676]	6	hSpCas9	negative selection	6168540
4946669	4946692	17	-	27260156	CADOES1	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.130228201974119	[681]	[568,735,499,510]	-2	hSpCas9	negative selection	6232790
4946620	4946643	17	+	27260156	CADOES1	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	0.37572004810548343	[1127]	[1471,1304,1163,1508]	6	hSpCas9	negative selection	6232791
4945899	4945922	17	+	27260156	CADOES1	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.45389198265180275	[331]	[241,246,205,205]	-7	hSpCas9	negative selection	6232792
4945980	4946003	17	-	27260156	EWS502	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.20553752628653155	[1105]	[810,859,900,1555]	-4	hSpCas9	negative selection	6289791
4946669	4946692	17	-	27260156	EWS502	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.7910464369078076	[681]	[346,414,466,450]	-8	hSpCas9	negative selection	6354041
4946620	4946643	17	+	27260156	EWS502	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.04006688075543696	[1127]	[984,995,1453,1246]	0	hSpCas9	negative selection	6354042
4945899	4945922	17	+	27260156	EWS502	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.748852215563849	[331]	[89,356,177,219]	-8	hSpCas9	negative selection	6354043
4945980	4946003	17	-	27260156	EW8	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.5526519789978063	[1105]	[885,556,443,613]	-7	hSpCas9	negative selection	6411042
4946669	4946692	17	-	27260156	EW8	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.8421302568408982	[681]	[363,242,314,314]	-9	hSpCas9	negative selection	6475292
4946620	4946643	17	+	27260156	EW8	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.4677564375985851	[1127]	[701,651,496,822]	-7	hSpCas9	negative selection	6475293
4945899	4945922	17	+	27260156	EW8	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.8028174114886236	[331]	[148,120,163,179]	-8	hSpCas9	negative selection	6475294
4945980	4946003	17	-	27260156	CORL105	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.6366829634597195	[1105]	[870,756,810,890]	-8	hSpCas9	negative selection	6532293
4946669	4946692	17	-	27260156	CORL105	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.5128301460872984	[681]	[577,544,690,445]	-7	hSpCas9	negative selection	6596543
4946620	4946643	17	+	27260156	CORL105	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.9479388222591033	[1127]	[697,661,729,655]	-9	hSpCas9	negative selection	6596544
4945899	4945922	17	+	27260156	CORL105	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.6495983402968869	[331]	[201,256,134,376]	-8	hSpCas9	negative selection	6596545
4945980	4946003	17	-	27260156	HS294T	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.29549195977083487	[1105]	[254,254,530,366]	-4	hSpCas9	negative selection	6653544
4946669	4946692	17	-	27260156	HS294T	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.7086233993016582	[681]	[182,123,165,172]	-7	hSpCas9	negative selection	6717794
4946620	4946643	17	+	27260156	HS294T	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.8116887897163658	[1127]	[195,212,283,317]	-8	hSpCas9	negative selection	6717795
4945899	4945922	17	+	27260156	HS294T	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-1.3943969518868635	[331]	[37,26,62,72]	-9	hSpCas9	negative selection	6717796
4945980	4946003	17	-	27260156	HCC44	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.9547842812527103	[1105]	[466,486,888,776]	-8	hSpCas9	negative selection	6774795
4946669	4946692	17	-	27260156	HCC44	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.0737303099683806	[681]	[353,431,293,359]	-8	hSpCas9	negative selection	6839045
4946620	4946643	17	+	27260156	HCC44	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.0224891233397755	[1127]	[705,485,720,636]	-8	hSpCas9	negative selection	6839046
4945899	4945922	17	+	27260156	HCC44	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-1.578351841326573	[331]	[150,66,219,91]	-9	hSpCas9	negative selection	6839047
4945980	4946003	17	-	27260156	G402	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-1.31509695048969	[1105]	[572,614,486,502]	-9	hSpCas9	negative selection	6896046
4946669	4946692	17	-	27260156	G402	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.6160015769220047	[681]	[504,225,619,782]	-6	hSpCas9	negative selection	6960296
4946620	4946643	17	+	27260156	G402	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.3068478859792638	[1127]	[752,436,335,710]	-9	hSpCas9	negative selection	6960297
4945899	4945922	17	+	27260156	G402	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-1.7380830746204765	[331]	[51,135,100,183]	-9	hSpCas9	negative selection	6960298
4945980	4946003	17	-	27260156	L33	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	0.14315204767927714	[1105]	[1106,527,792,1230]	3	hSpCas9	negative selection	7017297
4946669	4946692	17	-	27260156	L33	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.125880647046005	[681]	[706,270,340,586]	-3	hSpCas9	negative selection	7081547
4946620	4946643	17	+	27260156	L33	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.11634253698662778	[1127]	[1090,395,702,985]	-3	hSpCas9	negative selection	7081548
4945899	4945922	17	+	27260156	L33	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.42531663157693356	[331]	[242,151,111,196]	-7	hSpCas9	negative selection	7081549
4945980	4946003	17	-	27260156	K562	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-1.4205953908882383	[1105]	[637,425,329,124]	-9	hSpCas9	negative selection	7138548
4946669	4946692	17	-	27260156	K562	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.5871303050702776	[681]	[260,148,185,209]	-9	hSpCas9	negative selection	7202798
4946620	4946643	17	+	27260156	K562	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-2.0011855349198124	[1127]	[225,244,257,265]	-9	hSpCas9	negative selection	7202799
4945899	4945922	17	+	27260156	K562	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-1.8517853292185453	[331]	[160,113,30,33]	-9	hSpCas9	negative selection	7202800
4945980	4946003	17	-	27260156	HT29	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.6848173565028574	[1105]	[885,981,716,777]	-8	hSpCas9	negative selection	7259799
4946669	4946692	17	-	27260156	HT29	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.7652003867174536	[681]	[483,587,423,462]	-8	hSpCas9	negative selection	7324049
4946620	4946643	17	+	27260156	HT29	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.34530058414326625	[1127]	[1055,1224,1047,1000]	-6	hSpCas9	negative selection	7324050
4945899	4945922	17	+	27260156	HT29	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.9746677125794266	[331]	[275,186,192,171]	-8	hSpCas9	negative selection	7324051
4945980	4946003	17	-	27260156	MHHES1	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.4911167800697114	[1105]	[1240,924,836,628]	-7	hSpCas9	negative selection	7381050
4946669	4946692	17	-	27260156	MHHES1	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.5153437577958833	[681]	[903,523,435,357]	-7	hSpCas9	negative selection	7445300
4946620	4946643	17	+	27260156	MHHES1	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.4320296783419334	[1127]	[896,892,1125,842]	-7	hSpCas9	negative selection	7445301
4945899	4945922	17	+	27260156	MHHES1	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.9426236624721688	[331]	[182,358,172,96]	-9	hSpCas9	negative selection	7445302
4945980	4946003	17	-	27260156	MEWO	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	0.13843109680998555	[1105]	[1344,1031,1079]	3	hSpCas9	negative selection	7502301
4946669	4946692	17	-	27260156	MEWO	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.6627049039136703	[681]	[513,313,402]	-8	hSpCas9	negative selection	7566551
4946620	4946643	17	+	27260156	MEWO	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.18716333110777383	[1127]	[988,837,965]	-4	hSpCas9	negative selection	7566552
4945899	4945922	17	+	27260156	MEWO	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.5789563520139346	[331]	[362,166,123]	-8	hSpCas9	negative selection	7566553
4945980	4946003	17	-	27260156	LNCAPCLONEFGC	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.6094499304311911	[1105]	[523,409,1059,710]	-7	hSpCas9	negative selection	7623552
4946669	4946692	17	-	27260156	LNCAPCLONEFGC	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.989237497869043	[681]	[304,255,321,366]	-8	hSpCas9	negative selection	7687802
4946620	4946643	17	+	27260156	LNCAPCLONEFGC	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.6794556744238528	[1127]	[429,669,795,680]	-7	hSpCas9	negative selection	7687803
4945899	4945922	17	+	27260156	LNCAPCLONEFGC	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-1.3507307073754813	[331]	[75,97,267,53]	-9	hSpCas9	negative selection	7687804
4945980	4946003	17	-	27260156	PANC0327	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.9365310405753741	[1105]	[585,356,418,716]	-8	hSpCas9	negative selection	7744803
4946669	4946692	17	-	27260156	PANC0327	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.7563866861490474	[681]	[313,326,440,352]	-8	hSpCas9	negative selection	7809053
4946620	4946643	17	+	27260156	PANC0327	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.3076958635888873	[1127]	[353,292,344,636]	-9	hSpCas9	negative selection	7809054
4945899	4945922	17	+	27260156	PANC0327	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-1.7234177397861696	[331]	[32,162,44,101]	-9	hSpCas9	negative selection	7809055
4945980	4946003	17	-	27260156	NCIH2009	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-1.0076321725660382	[1105]	[1198,626,565]	-8	hSpCas9	negative selection	7866054
4946669	4946692	17	-	27260156	NCIH2009	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.0983282304456539	[681]	[612,365,389]	-8	hSpCas9	negative selection	7930304
4946620	4946643	17	+	27260156	NCIH2009	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.2967378603351931	[1127]	[640,768,510]	-8	hSpCas9	negative selection	7930305
4945899	4945922	17	+	27260156	NCIH2009	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-1.4299934076960894	[331]	[129,217,158]	-9	hSpCas9	negative selection	7930306
4945980	4946003	17	-	27260156	NCIH1373	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.2902766410678822	[1105]	[1259,850,1073,239]	-3	hSpCas9	negative selection	7987305
4946669	4946692	17	-	27260156	NCIH1373	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.62286236139946	[681]	[450,562,505,116]	-6	hSpCas9	negative selection	8051555
4946620	4946643	17	+	27260156	NCIH1373	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.5727994860447247	[1127]	[1108,505,897,253]	-5	hSpCas9	negative selection	8051556
4945899	4945922	17	+	27260156	NCIH1373	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-1.9514751974762121	[331]	[33,93,90,41]	-9	hSpCas9	negative selection	8051557
4945980	4946003	17	-	27260156	PATU8902	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-1.351053359982916	[1105]	[764,690,359,662]	-8	hSpCas9	negative selection	8108556
4946669	4946692	17	-	27260156	PATU8902	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.7542928037053527	[681]	[256,615,621,765]	-6	hSpCas9	negative selection	8172806
4946620	4946643	17	+	27260156	PATU8902	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.0282669731617955	[1127]	[943,839,492,880]	-7	hSpCas9	negative selection	8172807
4945899	4945922	17	+	27260156	PATU8902	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-2.9197349876965086	[331]	[15,210,11,12]	-9	hSpCas9	negative selection	8172808
4945980	4946003	17	-	27260156	PANC1	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-1.3984304406568664	[1105]	[274,564,313,329]	-9	hSpCas9	negative selection	8229807
4946669	4946692	17	-	27260156	PANC1	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.0095224404291816	[681]	[190,435,227,328]	-8	hSpCas9	negative selection	8294057
4946620	4946643	17	+	27260156	PANC1	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.5473183746759396	[1127]	[318,437,326,268]	-9	hSpCas9	negative selection	8294058
4945899	4945922	17	+	27260156	PANC1	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-3.0308226682003543	[331]	[22,72,9,39]	-9	hSpCas9	negative selection	8294059
4945980	4946003	17	-	27260156	PANC0813	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-1.2420006637814403	[1105]	[611,559,572,461]	-9	hSpCas9	negative selection	8351058
4946669	4946692	17	-	27260156	PANC0813	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.7280637375282497	[681]	[474,483,524,450]	-8	hSpCas9	negative selection	8415308
4946620	4946643	17	+	27260156	PANC0813	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.4367978263916483	[1127]	[425,698,486,346]	-9	hSpCas9	negative selection	8415309
4945899	4945922	17	+	27260156	PANC0813	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-1.629067259927024	[331]	[136,141,185,44]	-9	hSpCas9	negative selection	8415310
4945980	4946003	17	-	27260156	RDES	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.39813587758488156	[1105]	[845,803,1000,1268]	-6	hSpCas9	negative selection	8472309
4946669	4946692	17	-	27260156	RDES	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.7448042776093533	[681]	[378,468,465,579]	-8	hSpCas9	negative selection	8536559
4946620	4946643	17	+	27260156	RDES	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.4829271793622052	[1127]	[913,824,885,1092]	-7	hSpCas9	negative selection	8536560
4945899	4945922	17	+	27260156	RDES	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-1.488384292902182	[331]	[113,114,152,170]	-9	hSpCas9	negative selection	8536561
4945980	4946003	17	-	27260156	PC3	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.29451172479983023	[1105]	[537,879,1725,846]	-6	hSpCas9	negative selection	8593560
4946669	4946692	17	-	27260156	PC3	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.3059764330592176	[681]	[367,359,1353,462]	-6	hSpCas9	negative selection	8657810
4946620	4946643	17	+	27260156	PC3	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.27335429310156645	[1127]	[536,712,1469,1330]	-6	hSpCas9	negative selection	8657811
4945899	4945922	17	+	27260156	PC3	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.8465844793426286	[331]	[101,199,363,157]	-9	hSpCas9	negative selection	8657812
4945980	4946003	17	-	27260156	PATU8988T	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-1.140436938887505	[1105]	[324,338,649,619]	-9	hSpCas9	negative selection	8714811
4946669	4946692	17	-	27260156	PATU8988T	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.1196421450914196	[681]	[273,379,378,175]	-9	hSpCas9	negative selection	8779061
4946620	4946643	17	+	27260156	PATU8988T	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.7470235503727037	[1127]	[722,895,471,521]	-8	hSpCas9	negative selection	8779062
4945899	4945922	17	+	27260156	PATU8988T	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-1.7108344831863058	[331]	[103,37,181,57]	-9	hSpCas9	negative selection	8779063
4945980	4946003	17	-	27260156	T47D	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	0.024936689701779313	[1105]	[1462,1153,1254,1388]	0	hSpCas9	negative selection	8836062
4946669	4946692	17	-	27260156	T47D	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.21877128379243416	[681]	[744,636,611,743]	-5	hSpCas9	negative selection	8900312
4946620	4946643	17	+	27260156	T47D	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.031211871839697647	[1127]	[1370,977,1466,1353]	0	hSpCas9	negative selection	8900313
4945899	4945922	17	+	27260156	T47D	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.5584036705287049	[331]	[253,262,255,277]	-8	hSpCas9	negative selection	8900314
4945980	4946003	17	-	27260156	SU8686	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.1800422399211783	[1105]	[1081,950,842,974]	-3	hSpCas9	negative selection	8957313
4946669	4946692	17	-	27260156	SU8686	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.15757503012862656	[681]	[693,434,538,792]	-3	hSpCas9	negative selection	9021563
4946620	4946643	17	+	27260156	SU8686	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.07950793070322848	[1127]	[1087,971,1097,1079]	-1	hSpCas9	negative selection	9021564
4945899	4945922	17	+	27260156	SU8686	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.7980185340592664	[331]	[260,169,111,207]	-8	hSpCas9	negative selection	9021565
4945980	4946003	17	-	27260156	SKES1	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.2318607951824463	[1105]	[1063,1042,885,801]	-5	hSpCas9	negative selection	9078564
4946669	4946692	17	-	27260156	SKES1	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.0079517955726003	[681]	[435,404,244,291]	-9	hSpCas9	negative selection	9142814
4946620	4946643	17	+	27260156	SKES1	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.42304953038871373	[1127]	[1171,904,783,573]	-7	hSpCas9	negative selection	9142815
4945899	4945922	17	+	27260156	SKES1	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.7225306061481557	[331]	[256,238,135,183]	-9	hSpCas9	negative selection	9142816
4945980	4946003	17	-	27260156	TOV112D	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.4210918449912011	[1105]	[980,1219,626,595]	-7	hSpCas9	negative selection	9199815
4946669	4946692	17	-	27260156	TOV112D	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.6017493244380748	[681]	[725,465,408,231]	-8	hSpCas9	negative selection	9264065
4946620	4946643	17	+	27260156	TOV112D	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.33985532425230447	[1127]	[861,962,981,779]	-6	hSpCas9	negative selection	9264066
4945899	4945922	17	+	27260156	TOV112D	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.7398805763201012	[331]	[199,280,196,139]	-9	hSpCas9	negative selection	9264067
4945980	4946003	17	-	27260156	TC71	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.20964869249197493	[1105]	[828,1093,893,1309]	-5	hSpCas9	negative selection	9321066
4946669	4946692	17	-	27260156	TC71	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.3756046130713775	[681]	[461,621,554,620]	-8	hSpCas9	negative selection	9385316
4946620	4946643	17	+	27260156	TC71	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.2914298821828919	[1127]	[1005,1063,900,982]	-7	hSpCas9	negative selection	9385317
4945899	4945922	17	+	27260156	TC71	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.4670787472114615	[331]	[186,261,175,418]	-8	hSpCas9	negative selection	9385318
4945980	4946003	17	-	27260156	TC32	viability	TCCAGCGCTAGTCCTGCTGATGG	PFN1	ENSG00000108518	-0.292549725665487	[1105]	[878,535,1063,1027]	-5	hSpCas9	negative selection	9442317
4946669	4946692	17	-	27260156	TC32	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.561300701878183	[681]	[411,282,538,563]	-8	hSpCas9	negative selection	9506567
4946620	4946643	17	+	27260156	TC32	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.2453703504574165	[1127]	[850,810,926,977]	-4	hSpCas9	negative selection	9506568
4945899	4945922	17	+	27260156	TC32	viability	GTCAGTACTGGGAACGCCGAAGG	PFN1	ENSG00000108518	-0.6371984883251626	[331]	[103,196,215,294]	-8	hSpCas9	negative selection	9506569
4946669	4946692	17	-	27869803	HPAFII	viability after 27 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.8547067391171832	[388]	[73,41,NaN]	-8	hSpCas9	negative selection	9561739
4946672	4946695	17	-	27869803	HPAFII	viability after 27 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-1.1583927687341495	[131]	[17,41,NaN]	-7	hSpCas9	negative selection	9561740
4946669	4946692	17	-	27869803	HPAFII	viability after 15 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.7120681683804064	[388]	[171,99,NaN]	-9	hSpCas9	negative selection	9644188
4946672	4946695	17	-	27869803	HPAFII	viability after 15 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-1.4689131714426467	[131]	[41,56,NaN]	-8	hSpCas9	negative selection	9644189
4946669	4946692	17	-	27869803	ASPC1	viability after 36 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-2.3316379302546992	[1195]	[15,53,151]	-9	hSpCas9	negative selection	9726637
4946672	4946695	17	-	27869803	ASPC1	viability after 36 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-0.7928274247272358	[209]	[51,54,24]	-7	hSpCas9	negative selection	9726638
4946669	4946692	17	-	27869803	PATU8988S	viability after 35 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.7551158203789052	[859]	[150,53,NaN]	-8	hSpCas9	negative selection	9809086
4946672	4946695	17	-	27869803	PATU8988S	viability after 35 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-1.3573924372865354	[177]	[18,36,NaN]	-8	hSpCas9	negative selection	9809087
4946669	4946692	17	-	27869803	PATU8988S	viability after 31 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.4420849769182853	[859]	[156,86,NaN]	-8	hSpCas9	negative selection	9891535
4946672	4946695	17	-	27869803	PATU8988S	viability after 31 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-1.0943036020527401	[177]	[45,16,NaN]	-8	hSpCas9	negative selection	9891536
4946669	4946692	17	-	27869803	HPAFII	viability after 35 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-2.4973142910924446	[388]	[24,45,NaN]	-8	hSpCas9	negative selection	9973984
4946672	4946695	17	-	27869803	HPAFII	viability after 35 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-1.832194921414182	[131]	[22,13,NaN]	-7	hSpCas9	negative selection	9973985
4946669	4946692	17	-	27869803	HPAFII	viability after 31 days	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-2.1885165454640645	[388]	[78,13,NaN]	-8	hSpCas9	negative selection	10056433
4946672	4946695	17	-	27869803	HPAFII	viability after 31 days	GATCTTCGTACCAAGAGCACCGG	PFN1	ENSG00000108518	-1.3505566611660293	[131]	[18,39,NaN]	-7	hSpCas9	negative selection	10056434
4946811	4946834	17	-	28162770	P31FUJ	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-7.210082127914295	[125]	[0]	-9	hSpCas9	negative selection	10209930
4946669	4946692	17	-	28162770	P31FUJ	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-2.1242777476362096	[255]	[68]	-8	hSpCas9	negative selection	10209931
4946694	4946717	17	-	28162770	P31FUJ	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-1.859584880830162	[629]	[203]	-8	hSpCas9	negative selection	10209932
4946620	4946643	17	+	28162770	P31FUJ	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.981038910915605	[1284]	[764]	-6	hSpCas9	negative selection	10209933
4946811	4946834	17	-	28162770	TF1	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	NaN	[NaN]	[47]	1	hSpCas9	negative selection	10379296
4946669	4946692	17	-	28162770	TF1	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10379297
4946694	4946717	17	-	28162770	TF1	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	NaN	[NaN]	[97]	1	hSpCas9	negative selection	10379298
4946620	4946643	17	+	28162770	TF1	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	NaN	[NaN]	[777]	1	hSpCas9	negative selection	10379299
4946811	4946834	17	-	28162770	SKM1	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-3.7606011533578623	[45]	[5]	-9	hSpCas9	negative selection	10548662
4946669	4946692	17	-	28162770	SKM1	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.41537643855936174	[42]	[56]	-3	hSpCas9	negative selection	10548663
4946694	4946717	17	-	28162770	SKM1	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-1.8132844809208968	[164]	[82]	-8	hSpCas9	negative selection	10548664
4946620	4946643	17	+	28162770	SKM1	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.9159018369034873	[364]	[170]	-8	hSpCas9	negative selection	10548665
4946811	4946834	17	-	28162770	SKM1	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-3.7606011533578623	[45]	[5]	-9	hSpCas9	negative selection	10718028
4946669	4946692	17	-	28162770	SKM1	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.41537643855936174	[42]	[56]	-3	hSpCas9	negative selection	10718029
4946694	4946717	17	-	28162770	SKM1	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-1.8132844809208968	[164]	[82]	-8	hSpCas9	negative selection	10718030
4946620	4946643	17	+	28162770	SKM1	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.9159018369034873	[364]	[170]	-8	hSpCas9	negative selection	10718031
4946811	4946834	17	-	28162770	PL21	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-4.486360912693899	[102]	[1]	-9	hSpCas9	negative selection	10887394
4946669	4946692	17	-	28162770	PL21	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-2.500300103651772	[168]	[12]	-9	hSpCas9	negative selection	10887395
4946694	4946717	17	-	28162770	PL21	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-0.7047031524703397	[527]	[140]	-5	hSpCas9	negative selection	10887396
4946620	4946643	17	+	28162770	PL21	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.6285685483044616	[1054]	[296]	-4	hSpCas9	negative selection	10887397
4946811	4946834	17	-	28162770	P31FUJ	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-7.210082127914295	[125]	[0]	-9	hSpCas9	negative selection	11056760
4946669	4946692	17	-	28162770	P31FUJ	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-2.1242777476362096	[255]	[68]	-8	hSpCas9	negative selection	11056761
4946694	4946717	17	-	28162770	P31FUJ	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-1.859584880830162	[629]	[203]	-8	hSpCas9	negative selection	11056762
4946620	4946643	17	+	28162770	P31FUJ	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.981038910915605	[1284]	[764]	-6	hSpCas9	negative selection	11056763
4946811	4946834	17	-	28162770	OCIAML5	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-1.5566106873378256	[43]	[26]	-7	hSpCas9	negative selection	11226126
4946669	4946692	17	-	28162770	OCIAML5	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-2.557323305302865	[74]	[22]	-8	hSpCas9	negative selection	11226127
4946694	4946717	17	-	28162770	OCIAML5	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-2.1626666599498465	[443]	[178]	-8	hSpCas9	negative selection	11226128
4946620	4946643	17	+	28162770	OCIAML5	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.182083485728534	[938]	[746]	-6	hSpCas9	negative selection	11226129
4946811	4946834	17	-	28162770	EOL1	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-3.6868869405118128	[219]	[8]	-9	hSpCas9	negative selection	11395492
4946669	4946692	17	-	28162770	EOL1	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-0.04004689229826679	[321]	[164]	0	hSpCas9	negative selection	11395493
4946694	4946717	17	-	28162770	EOL1	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-0.7334781913403451	[728]	[230]	-5	hSpCas9	negative selection	11395494
4946620	4946643	17	+	28162770	EOL1	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.32936524429471126	[1418]	[594]	-2	hSpCas9	negative selection	11395495
4946811	4946834	17	-	28162770	MOLM13	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-2.3110837391432026	[150]	[21]	-8	hSpCas9	negative selection	11564858
4946669	4946692	17	-	28162770	MOLM13	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-2.122406563479618	[270]	[44]	-7	hSpCas9	negative selection	11564859
4946694	4946717	17	-	28162770	MOLM13	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-2.0651453271327163	[763]	[131]	-7	hSpCas9	negative selection	11564860
4946620	4946643	17	+	28162770	MOLM13	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-2.2283779541826707	[1898]	[292]	-7	hSpCas9	negative selection	11564861
4946811	4946834	17	-	28162770	HEL	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-6.723583382245459	[164]	[0]	-9	hSpCas9	negative selection	11734224
4946669	4946692	17	-	28162770	HEL	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-2.8729610062836857	[182]	[15]	-8	hSpCas9	negative selection	11734225
4946694	4946717	17	-	28162770	HEL	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-2.7164363061557735	[666]	[64]	-8	hSpCas9	negative selection	11734226
4946620	4946643	17	+	28162770	HEL	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.9591557344556374	[1456]	[479]	-5	hSpCas9	negative selection	11734227
4946811	4946834	17	-	28162770	MV411	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-5.7183467338793115	[124]	[1]	-9	hSpCas9	negative selection	11903590
4946669	4946692	17	-	28162770	MV411	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.0241588685544425	[168]	[69]	-6	hSpCas9	negative selection	11903591
4946694	4946717	17	-	28162770	MV411	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-0.28779957615840757	[441]	[304]	-2	hSpCas9	negative selection	11903592
4946620	4946643	17	+	28162770	MV411	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-0.4723722196527147	[1030]	[625]	-3	hSpCas9	negative selection	11903593
4946811	4946834	17	-	28162770	MONOMAC1	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-5.623301601761652	[85]	[1]	-9	hSpCas9	negative selection	12072956
4946669	4946692	17	-	28162770	MONOMAC1	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-2.706897892539991	[130]	[22]	-9	hSpCas9	negative selection	12072957
4946694	4946717	17	-	28162770	MONOMAC1	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-1.6064277831972555	[339]	[127]	-8	hSpCas9	negative selection	12072958
4946620	4946643	17	+	28162770	MONOMAC1	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.1672126316771585	[765]	[390]	-7	hSpCas9	negative selection	12072959
4946811	4946834	17	-	28162770	OCIAML2	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-3.3186267317971114	[26]	[14]	-9	hSpCas9	negative selection	12242322
4946669	4946692	17	-	28162770	OCIAML2	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.7925579201295232	[29]	[47]	-8	hSpCas9	negative selection	12242323
4946694	4946717	17	-	28162770	OCIAML2	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-1.1602897046300105	[74]	[185]	-6	hSpCas9	negative selection	12242324
4946620	4946643	17	+	28162770	OCIAML2	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.200377765127122	[215]	[520]	-7	hSpCas9	negative selection	12242325
4946811	4946834	17	-	28162770	OCIAML3	viability	GTTCCTCTTCCAGCCAGCTGAGG	PFN1	ENSG00000108518	-6.237863830098888	[24]	[0]	-9	hSpCas9	negative selection	12411688
4946669	4946692	17	-	28162770	OCIAML3	viability	CTTCGTACCAAGAGCACCGGTGG	PFN1	ENSG00000108518	-1.037614291799778	[50]	[74]	-6	hSpCas9	negative selection	12411689
4946694	4946717	17	-	28162770	OCIAML3	viability	GCAGGATGGGGAATTTAGCATGG	PFN1	ENSG00000108518	-1.2968066313391775	[152]	[187]	-7	hSpCas9	negative selection	12411690
4946620	4946643	17	+	28162770	OCIAML3	viability	GAACTCACTCTTGTCAGTCTTGG	PFN1	ENSG00000108518	-1.0370595157726035	[311]	[458]	-6	hSpCas9	negative selection	12411691