Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5256
• Symbol: PHKA2
• Description: phosphorylase kinase regulatory subunit alpha 2

DataSource: http://genomecrispr.dkfz.de/#!/results/PHKA2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
18951152	18951175	X	-	26472758	Jiyoye	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	0.1401829621033961	[218]	[181]	1	hSpCas9	negative selection	119976
18901500	18901523	X	-	26472758	Jiyoye	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	1.094137595729425	[181]	[292]	7	hSpCas9	negative selection	119977
18951140	18951163	X	+	26472758	Jiyoye	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	-0.31442181123712853	[248]	[150]	-2	hSpCas9	negative selection	119978
18936123	18936146	X	-	26472758	Jiyoye	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	1.5915999526433007	[65]	[149]	8	hSpCas9	negative selection	119979
18936107	18936130	X	-	26472758	Jiyoye	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	-0.4146791102468459	[349]	[197]	-3	hSpCas9	negative selection	119980
18924453	18924476	X	-	26472758	Jiyoye	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	-0.27871602806606344	[36]	[22]	-2	hSpCas9	negative selection	119981
18918738	18918761	X	+	26472758	Jiyoye	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	4.930737337562886	[0]	[22]	9	hSpCas9	negative selection	119982
18908894	18908917	X	-	26472758	Jiyoye	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.023031890172813485	[230]	[176]	0	hSpCas9	negative selection	119983
18907055	18907078	X	-	26472758	Jiyoye	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.5364583984508398	[95]	[104]	4	hSpCas9	negative selection	119984
18907018	18907041	X	+	26472758	Jiyoye	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	0.025926195683313003	[210]	[161]	0	hSpCas9	negative selection	119985
18951152	18951175	X	-	26472758	KBM7	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	0.005194817906256782	[629,241]	[227,169]	0	hSpCas9	negative selection	311094
18901500	18901523	X	-	26472758	KBM7	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	0.45113842190017683	[1080,856]	[664,576]	5	hSpCas9	negative selection	311095
18951140	18951163	X	+	26472758	KBM7	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	0.07630010955979549	[1253,694]	[522,424]	0	hSpCas9	negative selection	311096
18936123	18936146	X	-	26472758	KBM7	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	0.24768760354199323	[497,251]	[262,149]	2	hSpCas9	negative selection	311097
18936107	18936130	X	-	26472758	KBM7	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.23237735359707	[720,518]	[320,353]	2	hSpCas9	negative selection	311098
18924453	18924476	X	-	26472758	KBM7	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	0.9748498609279259	[288,204]	[198,248]	9	hSpCas9	negative selection	311099
18918738	18918761	X	+	26472758	KBM7	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	0.4969171475244396	[71,35]	[19,47]	5	hSpCas9	negative selection	311100
18908894	18908917	X	-	26472758	KBM7	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.33773144476329175	[952,733]	[430,555]	3	hSpCas9	negative selection	311101
18907055	18907078	X	-	26472758	KBM7	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.32155753203545	[580,425]	[242,336]	3	hSpCas9	negative selection	311102
18907018	18907041	X	+	26472758	KBM7	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	0.3306135328916549	[819,457]	[373,363]	3	hSpCas9	negative selection	311103
18951152	18951175	X	-	26472758	Raji	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	-0.0739462293409624	[253]	[55]	0	hSpCas9	negative selection	502212
18901500	18901523	X	-	26472758	Raji	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	0.2506786969332979	[564]	[155]	2	hSpCas9	negative selection	502213
18951140	18951163	X	+	26472758	Raji	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	-0.32440103874239723	[490]	[90]	-3	hSpCas9	negative selection	502214
18936123	18936146	X	-	26472758	Raji	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	0.005845508911537151	[205]	[47]	0	hSpCas9	negative selection	502215
18936107	18936130	X	-	26472758	Raji	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.7125239180323861	[354]	[134]	6	hSpCas9	negative selection	502216
18924453	18924476	X	-	26472758	Raji	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	0.23744407593797234	[105]	[28]	2	hSpCas9	negative selection	502217
18918738	18918761	X	+	26472758	Raji	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	0.7568862882894662	[50]	[19]	7	hSpCas9	negative selection	502218
18908894	18908917	X	-	26472758	Raji	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.7892075753473448	[383]	[153]	7	hSpCas9	negative selection	502219
18907055	18907078	X	-	26472758	Raji	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	1.3682001159575745	[216]	[129]	9	hSpCas9	negative selection	502220
18907018	18907041	X	+	26472758	Raji	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	0.26259618529453965	[448]	[124]	2	hSpCas9	negative selection	502221
18951152	18951175	X	-	26472758	K562	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	-0.26956062130603314	[346]	[242]	-2	hSpCas9	negative selection	693330
18901500	18901523	X	-	26472758	K562	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	1.3857415817938978	[582]	[1285]	9	hSpCas9	negative selection	693331
18951140	18951163	X	+	26472758	K562	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	-0.27914322839056604	[712]	[495]	-2	hSpCas9	negative selection	693332
18936123	18936146	X	-	26472758	K562	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	-0.018615678167346883	[275]	[229]	0	hSpCas9	negative selection	693333
18936107	18936130	X	-	26472758	K562	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	1.560943464024476	[427]	[1065]	9	hSpCas9	negative selection	693334
18924453	18924476	X	-	26472758	K562	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	0.18856549293292946	[157]	[151]	1	hSpCas9	negative selection	693335
18918738	18918761	X	+	26472758	K562	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	-0.3613023332215066	[69]	[45]	-2	hSpCas9	negative selection	693336
18908894	18908917	X	-	26472758	K562	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.5155875612414195	[618]	[746]	4	hSpCas9	negative selection	693337
18907055	18907078	X	-	26472758	K562	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.8699353267382379	[303]	[468]	7	hSpCas9	negative selection	693338
18907018	18907041	X	+	26472758	K562	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	0.8478302654873795	[517]	[786]	7	hSpCas9	negative selection	693339
18941575	18941598	X	+	26627737	DLD1	viability	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	0.29497913131141706	[437]	[237,148,122]	3	hSpCas9	negative selection	845280
18945077	18945100	X	-	26627737	DLD1	viability	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	1.452679455258838	[183]	[181,188,109]	9	hSpCas9	negative selection	845281
18951260	18951283	X	-	26627737	DLD1	viability	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.2371457747858713	[824]	[319,361,241]	2	hSpCas9	negative selection	845282
18952535	18952558	X	-	26627737	DLD1	viability	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	-0.3987727819699809	[841]	[169,257,176]	-4	hSpCas9	negative selection	845283
18954253	18954276	X	-	26627737	DLD1	viability	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	1.0624298983934277	[366]	[260,235,223]	8	hSpCas9	negative selection	845284
18983845	18983868	X	+	26627737	DLD1	viability	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.5497299691335515	[1524]	[448,963,692]	5	hSpCas9	negative selection	845285
18941575	18941598	X	+	26627737	GBM cells	viability after 5 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	-0.7508997701854386	[363]	[78,152]	-8	hSpCas9	negative selection	927595
18945077	18945100	X	-	26627737	GBM cells	viability after 5 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	0.23085575840106715	[200]	[111,140]	3	hSpCas9	negative selection	927596
18951260	18951283	X	-	26627737	GBM cells	viability after 5 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.24516739219263495	[493]	[330,296]	4	hSpCas9	negative selection	927597
18952535	18952558	X	-	26627737	GBM cells	viability after 5 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.22767760002253723	[378]	[219,255]	3	hSpCas9	negative selection	927598
18954253	18954276	X	-	26627737	GBM cells	viability after 5 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	0.4085882483026045	[235]	[153,181]	6	hSpCas9	negative selection	927599
18983845	18983868	X	+	26627737	GBM cells	viability after 5 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	-0.2639477340340579	[814]	[297,429]	-4	hSpCas9	negative selection	927600
18941575	18941598	X	+	26627737	GBM cells	viability after 13 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	-0.6786132880467359	[363]	[145,104]	-7	hSpCas9	negative selection	1009910
18945077	18945100	X	-	26627737	GBM cells	viability after 13 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	0.7436176251006263	[200]	[218,152]	8	hSpCas9	negative selection	1009911
18951260	18951283	X	-	26627737	GBM cells	viability after 13 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.4649166456782772	[493]	[407,338]	6	hSpCas9	negative selection	1009912
18952535	18952558	X	-	26627737	GBM cells	viability after 13 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.5766227568575697	[378]	[352,268]	7	hSpCas9	negative selection	1009913
18954253	18954276	X	-	26627737	GBM cells	viability after 13 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	0.728730922045583	[235]	[193,226]	8	hSpCas9	negative selection	1009914
18983845	18983868	X	+	26627737	GBM cells	viability after 13 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	-0.05913231200957014	[814]	[483,375]	0	hSpCas9	negative selection	1009915
18941575	18941598	X	+	26627737	GBM cells	viability after 21 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	-0.865271590056965	[363]	[118,98]	-6	hSpCas9	negative selection	1092225
18945077	18945100	X	-	26627737	GBM cells	viability after 21 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	0.7285846113903209	[200]	[193,168]	7	hSpCas9	negative selection	1092226
18951260	18951283	X	-	26627737	GBM cells	viability after 21 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.29833400168916113	[493]	[340,319]	3	hSpCas9	negative selection	1092227
18952535	18952558	X	-	26627737	GBM cells	viability after 21 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.7452821570233694	[378]	[364,326]	7	hSpCas9	negative selection	1092228
18954253	18954276	X	-	26627737	GBM cells	viability after 21 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	-0.27267572481105257	[235]	[102,108]	-3	hSpCas9	negative selection	1092229
18983845	18983868	X	+	26627737	GBM cells	viability after 21 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.1939638604913949	[814]	[541,473]	2	hSpCas9	negative selection	1092230
18941575	18941598	X	+	26627737	RPE1	viability after 9 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	0.726470086730634	[1053]	[345,803]	5	hSpCas9	negative selection	1174540
18945077	18945100	X	-	26627737	RPE1	viability after 9 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	1.8864245891178393	[143]	[160,173]	8	hSpCas9	negative selection	1174541
18951260	18951283	X	-	26627737	RPE1	viability after 9 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.20104509951408733	[1915]	[582,826]	1	hSpCas9	negative selection	1174542
18952535	18952558	X	-	26627737	RPE1	viability after 9 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.9189458756287583	[960]	[553,587]	6	hSpCas9	negative selection	1174543
18954253	18954276	X	-	26627737	RPE1	viability after 9 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	-0.1580412443891921	[866]	[282,191]	-1	hSpCas9	negative selection	1174544
18983845	18983868	X	+	26627737	RPE1	viability after 9 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.15159287924467124	[2986]	[1067,1000]	1	hSpCas9	negative selection	1174545
18941575	18941598	X	+	26627737	RPE1	viability after 12 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	0.812051839840026	[1053]	[434,562]	5	hSpCas9	negative selection	1256855
18945077	18945100	X	-	26627737	RPE1	viability after 12 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	2.0667995419567764	[143]	[198,122]	9	hSpCas9	negative selection	1256856
18951260	18951283	X	-	26627737	RPE1	viability after 12 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.29300701068612156	[1915]	[568,695]	2	hSpCas9	negative selection	1256857
18952535	18952558	X	-	26627737	RPE1	viability after 12 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	1.392495430404785	[960]	[603,755]	7	hSpCas9	negative selection	1256858
18954253	18954276	X	-	26627737	RPE1	viability after 12 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	0.5574465276764403	[866]	[369,313]	3	hSpCas9	negative selection	1256859
18983845	18983868	X	+	26627737	RPE1	viability after 12 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.10904371127556756	[2986]	[1035,684]	0	hSpCas9	negative selection	1256860
18941575	18941598	X	+	26627737	RPE1	viability after 15 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	0.250348302027191	[1053]	[317,389]	1	hSpCas9	negative selection	1339170
18945077	18945100	X	-	26627737	RPE1	viability after 15 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	2.322103609234522	[143]	[276,132]	9	hSpCas9	negative selection	1339171
18951260	18951283	X	-	26627737	RPE1	viability after 15 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.6082759067185437	[1915]	[812,838]	4	hSpCas9	negative selection	1339172
18952535	18952558	X	-	26627737	RPE1	viability after 15 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	1.2253510816824102	[960]	[516,749]	7	hSpCas9	negative selection	1339173
18954253	18954276	X	-	26627737	RPE1	viability after 15 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	0.8806452735243805	[866]	[447,454]	5	hSpCas9	negative selection	1339174
18983845	18983868	X	+	26627737	RPE1	viability after 15 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.14322800110186895	[2986]	[1177,696]	0	hSpCas9	negative selection	1339175
18941575	18941598	X	+	26627737	RPE1	viability after 18 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	0.30934307145158363	[1053]	[365,337]	2	hSpCas9	negative selection	1421485
18945077	18945100	X	-	26627737	RPE1	viability after 18 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	2.216488201078504	[143]	[212,145]	9	hSpCas9	negative selection	1421486
18951260	18951283	X	-	26627737	RPE1	viability after 18 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.42230061494621807	[1915]	[558,835]	2	hSpCas9	negative selection	1421487
18952535	18952558	X	-	26627737	RPE1	viability after 18 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	1.4744291579516702	[960]	[826,606]	7	hSpCas9	negative selection	1421488
18954253	18954276	X	-	26627737	RPE1	viability after 18 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	0.5905319559208424	[866]	[317,388]	3	hSpCas9	negative selection	1421489
18983845	18983868	X	+	26627737	RPE1	viability after 18 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.5859554667425941	[2986]	[1529,867]	3	hSpCas9	negative selection	1421490
18941575	18941598	X	+	26627737	HeLa	viability after 8 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	0.034731712470610576	[504]	[284,200,203]	0	hSpCas9	negative selection	1503800
18945077	18945100	X	-	26627737	HeLa	viability after 8 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	0.3296379869392785	[221]	[105,165,90]	3	hSpCas9	negative selection	1503801
18951260	18951283	X	-	26627737	HeLa	viability after 8 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.7423454885239091	[531]	[645,233,341]	6	hSpCas9	negative selection	1503802
18952535	18952558	X	-	26627737	HeLa	viability after 8 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.9696720902534623	[363]	[276,272,368]	7	hSpCas9	negative selection	1503803
18954253	18954276	X	-	26627737	HeLa	viability after 8 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	1.3565803028845689	[191]	[388,249,52]	8	hSpCas9	negative selection	1503804
18983845	18983868	X	+	26627737	HeLa	viability after 8 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.25521316537516214	[1108]	[499,425,770]	2	hSpCas9	negative selection	1503805
18941575	18941598	X	+	26627737	HeLa	viability after 12 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	-0.29110434968789317	[504]	[137,120,256]	-3	hSpCas9	negative selection	1586115
18945077	18945100	X	-	26627737	HeLa	viability after 12 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	0.3141338414578837	[221]	[40,142,152]	2	hSpCas9	negative selection	1586116
18951260	18951283	X	-	26627737	HeLa	viability after 12 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.5693129283351712	[531]	[361,266,356]	5	hSpCas9	negative selection	1586117
18952535	18952558	X	-	26627737	HeLa	viability after 12 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.6539848667168432	[363]	[182,288,230]	5	hSpCas9	negative selection	1586118
18954253	18954276	X	-	26627737	HeLa	viability after 12 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	1.8617003958297353	[191]	[350,268,248]	9	hSpCas9	negative selection	1586119
18983845	18983868	X	+	26627737	HeLa	viability after 12 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.4359005621751948	[1108]	[767,527,577]	4	hSpCas9	negative selection	1586120
18941575	18941598	X	+	26627737	HeLa	viability after 15 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	-0.07051902512618863	[504]	[221,132,234]	0	hSpCas9	negative selection	1668430
18945077	18945100	X	-	26627737	HeLa	viability after 15 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	1.0361228134308351	[221]	[195,172,186]	7	hSpCas9	negative selection	1668431
18951260	18951283	X	-	26627737	HeLa	viability after 15 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.8947913874200544	[531]	[476,340,387]	6	hSpCas9	negative selection	1668432
18952535	18952558	X	-	26627737	HeLa	viability after 15 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.6711014168507151	[363]	[277,317,100]	5	hSpCas9	negative selection	1668433
18954253	18954276	X	-	26627737	HeLa	viability after 15 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	1.2211416264466692	[191]	[129,190,229]	8	hSpCas9	negative selection	1668434
18983845	18983868	X	+	26627737	HeLa	viability after 15 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.5015583653143121	[1108]	[616,598,706]	4	hSpCas9	negative selection	1668435
18941575	18941598	X	+	26627737	HeLa	viability after 18 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	0.008869974926700552	[504]	[164,116,234]	0	hSpCas9	negative selection	1750745
18945077	18945100	X	-	26627737	HeLa	viability after 18 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	1.0968225859216596	[221]	[139,151,186]	7	hSpCas9	negative selection	1750746
18951260	18951283	X	-	26627737	HeLa	viability after 18 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.8685159191358032	[531]	[310,275,387]	6	hSpCas9	negative selection	1750747
18952535	18952558	X	-	26627737	HeLa	viability after 18 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.6711683253770935	[363]	[189,258,100]	5	hSpCas9	negative selection	1750748
18954253	18954276	X	-	26627737	HeLa	viability after 18 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	1.2654379143565373	[191]	[91,165,229]	8	hSpCas9	negative selection	1750749
18983845	18983868	X	+	26627737	HeLa	viability after 18 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.4994950033698786	[1108]	[412,494,706]	4	hSpCas9	negative selection	1750750
18941575	18941598	X	+	26627737	HCT116	viability after 6 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	-1.1149309007740722	[871]	[32,79]	-6	hSpCas9	negative selection	1833060
18945077	18945100	X	-	26627737	HCT116	viability after 6 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	0.19577084267791064	[477]	[223,9]	1	hSpCas9	negative selection	1833061
18951260	18951283	X	-	26627737	HCT116	viability after 6 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	-1.0578666670801435	[1528]	[157,91]	-6	hSpCas9	negative selection	1833062
18952535	18952558	X	-	26627737	HCT116	viability after 6 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.6105564838903302	[1049]	[48,363]	3	hSpCas9	negative selection	1833063
18954253	18954276	X	-	26627737	HCT116	viability after 6 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	1.0476419828301073	[493]	[282,92]	5	hSpCas9	negative selection	1833064
18983845	18983868	X	+	26627737	HCT116	viability after 6 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	1.6279486285844271	[1212]	[308,743]	8	hSpCas9	negative selection	1833065
18941575	18941598	X	+	26627737	HCT116	viability after 8 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	0.2756425184494932	[357]	[280,184,250]	3	hSpCas9	negative selection	1915375
18945077	18945100	X	-	26627737	HCT116	viability after 8 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	1.3780450683988297	[95]	[147,154,109]	9	hSpCas9	negative selection	1915376
18951260	18951283	X	-	26627737	HCT116	viability after 8 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.1552210740146539	[505]	[361,309,260]	1	hSpCas9	negative selection	1915377
18952535	18952558	X	-	26627737	HCT116	viability after 8 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.12487906957049744	[508]	[359,296,261]	1	hSpCas9	negative selection	1915378
18954253	18954276	X	-	26627737	HCT116	viability after 8 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	0.7906820837106674	[174]	[173,277,49]	7	hSpCas9	negative selection	1915379
18983845	18983868	X	+	26627737	HCT116	viability after 8 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.41924641083446446	[743]	[681,413,550]	4	hSpCas9	negative selection	1915380
18941575	18941598	X	+	26627737	HCT116	viability after 9 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	-0.18504645454369917	[871]	[239,176]	-1	hSpCas9	negative selection	1997690
18945077	18945100	X	-	26627737	HCT116	viability after 9 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	0.04091539999783528	[477]	[94,159]	0	hSpCas9	negative selection	1997691
18951260	18951283	X	-	26627737	HCT116	viability after 9 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	-0.8837170656409892	[1528]	[232,211]	-6	hSpCas9	negative selection	1997692
18952535	18952558	X	-	26627737	HCT116	viability after 9 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.2032807555479763	[1049]	[381,275]	1	hSpCas9	negative selection	1997693
18954253	18954276	X	-	26627737	HCT116	viability after 9 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	0.48898728102866457	[493]	[78,268]	3	hSpCas9	negative selection	1997694
18983845	18983868	X	+	26627737	HCT116	viability after 9 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.5212376355846756	[1212]	[389,523]	4	hSpCas9	negative selection	1997695
18941575	18941598	X	+	26627737	HCT116	viability after 12 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	0.14362512891478385	[357]	[250,219,148]	1	hSpCas9	negative selection	2080005
18945077	18945100	X	-	26627737	HCT116	viability after 12 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	1.0536728766863455	[95]	[135,86,87]	8	hSpCas9	negative selection	2080006
18951260	18951283	X	-	26627737	HCT116	viability after 12 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.2316400852262892	[505]	[294,344,298]	2	hSpCas9	negative selection	2080007
18952535	18952558	X	-	26627737	HCT116	viability after 12 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.23915893645577557	[508]	[242,498,215]	2	hSpCas9	negative selection	2080008
18954253	18954276	X	-	26627737	HCT116	viability after 12 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	1.261884093623429	[174]	[210,200,249]	8	hSpCas9	negative selection	2080009
18983845	18983868	X	+	26627737	HCT116	viability after 12 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.0441290205407483	[743]	[367,423,420]	0	hSpCas9	negative selection	2080010
18941575	18941598	X	+	26627737	HCT116	viability after 15 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	0.2264336631359813	[357]	[295,161,269]	2	hSpCas9	negative selection	2162320
18945077	18945100	X	-	26627737	HCT116	viability after 15 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	1.2820247059588132	[95]	[169,136,99]	8	hSpCas9	negative selection	2162321
18951260	18951283	X	-	26627737	HCT116	viability after 15 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.42542339058315315	[505]	[336,329,495]	4	hSpCas9	negative selection	2162322
18952535	18952558	X	-	26627737	HCT116	viability after 15 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.2339572890528656	[508]	[432,414,195]	2	hSpCas9	negative selection	2162323
18954253	18954276	X	-	26627737	HCT116	viability after 15 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	1.170685144605957	[174]	[117,273,272]	8	hSpCas9	negative selection	2162324
18983845	18983868	X	+	26627737	HCT116	viability after 15 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.42746286424645685	[743]	[662,526,544]	4	hSpCas9	negative selection	2162325
18941575	18941598	X	+	26627737	HCT116	viability after 18 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	0.24298323157763346	[357]	[190,205,217]	2	hSpCas9	negative selection	2244635
18945077	18945100	X	-	26627737	HCT116	viability after 18 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	1.1205086852448964	[95]	[126,104,68]	8	hSpCas9	negative selection	2244636
18951260	18951283	X	-	26627737	HCT116	viability after 18 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	-0.049674257043471615	[505]	[224,189,299]	0	hSpCas9	negative selection	2244637
18952535	18952558	X	-	26627737	HCT116	viability after 18 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	-0.12160062127368276	[508]	[179,326,161]	-1	hSpCas9	negative selection	2244638
18954253	18954276	X	-	26627737	HCT116	viability after 18 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	1.19684427916961	[174]	[253,184,140]	8	hSpCas9	negative selection	2244639
18983845	18983868	X	+	26627737	HCT116	viability after 18 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.3570151814251963	[743]	[545,288,562]	3	hSpCas9	negative selection	2244640
18984486	18984509	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGACTCAGGGAGGCAACCTGG	PHKA2	ENSG00000044446	0.6307198198185943	[72,85]	[21,31]	2	dCas9-VP64	positive selection	2383576
18984537	18984560	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGCCTGTTTCTCTGGCCTTGG	PHKA2	ENSG00000044446	0.2171645958698425	[385,84]	[102,11]	1	dCas9-VP64	positive selection	2383577
18984448	18984471	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GATTTCGCAGCGGCTCTCCCGGG	PHKA2	ENSG00000044446	-1.1753280241066888	[853,315]	[51,60]	-6	dCas9-VP64	positive selection	2383578
18973026	18973049	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCATTCTGTCGCCCAGG	PHKA2	ENSG00000044446	1.2945245935016754	[8,39]	[14,10]	5	dCas9-VP64	positive selection	2416736
18956071	18956094	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCTCAGCCTCCCAAAGTGCTTAG	PHKA2	ENSG00000044446	-0.5682190535479439	[619,834]	[60,158]	-3	dCas9-VP64	positive selection	2453262
18912866	18912889	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATGCCATTGCACTCCAGCCTCGG	PHKA2	ENSG00000044446	2.033062228314259	[28,209]	[4,221]	7	dCas9-VP64	positive selection	2456494
18912815	18912838	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGGAGAATCGCTTGAACCTGG	PHKA2	ENSG00000044446	-0.7872021050505377	[82,16]	[7,2]	-4	dCas9-VP64	positive selection	2464299
18953784	18953807	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGAAACCAGCCTGGCCAACACGG	PHKA2	ENSG00000044446	0.4780801974693999	[28,77]	[7,24]	2	dCas9-VP64	positive selection	2472872
18984486	18984509	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGACTCAGGGAGGCAACCTGG	PHKA2	ENSG00000044446	0.28745169605506804	[86,40]	[39,11]	2	dCas9-VP64	positive selection	2478831
18984537	18984560	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGCCTGTTTCTCTGGCCTTGG	PHKA2	ENSG00000044446	0.07011216384946428	[43,84]	[15,26]	0	dCas9-VP64	positive selection	2478832
18984448	18984471	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GATTTCGCAGCGGCTCTCCCGGG	PHKA2	ENSG00000044446	-0.627525948991396	[216,237]	[64,30]	-6	dCas9-VP64	positive selection	2478833
18973026	18973049	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCATTCTGTCGCCCAGG	PHKA2	ENSG00000044446	0.5675992743301584	[132,99]	[41,68]	4	dCas9-VP64	positive selection	2511991
18956071	18956094	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCTCAGCCTCCCAAAGTGCTTAG	PHKA2	ENSG00000044446	-0.30228362212427595	[344,254]	[89,69]	-3	dCas9-VP64	positive selection	2548517
18912866	18912889	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATGCCATTGCACTCCAGCCTCGG	PHKA2	ENSG00000044446	0.2042793589460996	[254,297]	[44,158]	1	dCas9-VP64	positive selection	2551749
18912815	18912838	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGGAGAATCGCTTGAACCTGG	PHKA2	ENSG00000044446	-0.42856361530074616	[34,35]	[8,6]	-4	dCas9-VP64	positive selection	2559554
18953784	18953807	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGAAACCAGCCTGGCCAACACGG	PHKA2	ENSG00000044446	0.26160550637758195	[116,79]	[45,30]	2	dCas9-VP64	positive selection	2568127
18920165	18920188	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGTGGTGAGAAATTCCGAAAGG	PHKA2	ENSG00000044446	0.31932395148093107	[3,3]	[3,3]	6	hSpCas9	positive selection	3011100
18936132	18936155	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGGTCCAAGAATACCGAGAGG	PHKA2	ENSG00000044446	-0.30747417461694504	[4,4]	[4,0]	-4	hSpCas9	positive selection	3011101
18926534	18926557	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACTTATTGAGGAAACACGGGG	PHKA2	ENSG00000044446	-0.20061952707322817	[2,2]	[0,3]	-3	hSpCas9	positive selection	3011102
18954398	18954421	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTAATAGAATCCCGTCACGGGG	PHKA2	ENSG00000044446	-0.08293268489921876	[3,2]	[2,2]	-1	hSpCas9	positive selection	3011103
18920165	18920188	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGTGGTGAGAAATTCCGAAAGG	PHKA2	ENSG00000044446	0.2760446537630639	[3,3]	[4,2]	5	hSpCas9	positive selection	3078958
18936132	18936155	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGGTCCAAGAATACCGAGAGG	PHKA2	ENSG00000044446	-0.23800733354508616	[4,4]	[3,1]	-4	hSpCas9	positive selection	3078959
18926534	18926557	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACTTATTGAGGAAACACGGGG	PHKA2	ENSG00000044446	-0.040111818065228844	[2,2]	[1,1]	0	hSpCas9	positive selection	3078960
18954398	18954421	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTAATAGAATCCCGTCACGGGG	PHKA2	ENSG00000044446	-0.4061991291778016	[3,3]	[1,1]	-6	hSpCas9	positive selection	3078961
18952519	18952542		-	24336571	A375	resistance to PLX after 7 days	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.10871530814520097	[17,13]	[16,16]	3	hSpCas9	positive selection	3135361
18954344	18954367		+	24336571	A375	resistance to PLX after 7 days	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.0200851499527782	[10,12]	[13,9]	0	hSpCas9	positive selection	3135363
18954301	18954324		+	24336571	A375	resistance to PLX after 7 days	TCTTACGGTAGGCCATGCCCAGG	PHKA2	ENSG00000044446	-0.06047064938854185	[30,32]	[29,30]	-2	hSpCas9	positive selection	3135364
18952519	18952542		-	24336571	A375	resistance to PLX after 14 days	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.4230811319174025	[10,10]	[6,5]	4	hSpCas9	positive selection	3193154
18954344	18954367		+	24336571	A375	resistance to PLX after 14 days	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	-0.2268471147781073	[13,11]	[5,3]	-2	hSpCas9	positive selection	3193156
18954301	18954324		+	24336571	A375	resistance to PLX after 14 days	TCTTACGGTAGGCCATGCCCAGG	PHKA2	ENSG00000044446	-0.4294226915101651	[29,36]	[12,9]	-5	hSpCas9	positive selection	3193157
18952519	18952542		-	24336571	A375	viability after 7 days	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.4565092221433562	[11]	[17,13]	7	hSpCas9	negative selection	3250947
18954344	18954367		+	24336571	A375	viability after 7 days	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	-0.1558033662786047	[13]	[10,12]	-2	hSpCas9	negative selection	3250949
18954301	18954324		+	24336571	A375	viability after 7 days	TCTTACGGTAGGCCATGCCCAGG	PHKA2	ENSG00000044446	0.58293958665981	[21]	[30,32]	8	hSpCas9	negative selection	3250950
18952519	18952542		-	24336571	A375	viability after 14 days	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.05901310485314734	[11]	[10,10]	0	hSpCas9	negative selection	3308740
18954344	18954367		+	24336571	A375	viability after 14 days	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	-0.006962213606254583	[13]	[13,11]	0	hSpCas9	negative selection	3308742
18954301	18954324		+	24336571	A375	viability after 14 days	TCTTACGGTAGGCCATGCCCAGG	PHKA2	ENSG00000044446	0.6766495730212506	[21]	[29,36]	8	hSpCas9	negative selection	3308743
18951098	18951121	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	-0.3573836326693731	[195,195]	[0,0]	-2	hSpCas9	positive selection	3385676
18952519	18952542	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.04645453673126785	[157,157]	[0,0]	0	hSpCas9	positive selection	3385677
18952493	18952516	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	0.08740121000352279	[143,143]	[0,0]	0	hSpCas9	positive selection	3385678
18920164	18920187	X	+	26780180	HT29	viability (Avana library 4 designs)	ATGTGGTGAGAAATTCCGAAAGG	PHKA2	ENSG00000044446	1.85510563081781	[]	[]	7	hSpCas9	negative selection	3449175
18936132	18936155	X	-	26780180	HT29	viability (Avana library 4 designs)	CCAGGTCCAAGAATACCGAGAGG	PHKA2	ENSG00000044446	-0.0795679540772875	[]	[]	-1	hSpCas9	negative selection	3449176
18926534	18926557	X	-	26780180	HT29	viability (Avana library 4 designs)	GGACTTATTGAGGAAACACGGGG	PHKA2	ENSG00000044446	2.29729668850926	[]	[]	8	hSpCas9	negative selection	3449177
18954398	18954421	X	-	26780180	HT29	viability (Avana library 4 designs)	TCTAATAGAATCCCGTCACGGGG	PHKA2	ENSG00000044446	1.5079720271505	[]	[]	6	hSpCas9	negative selection	3449178
18954398	18954421	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTAATAGAATCCCGTCACGGGG	PHKA2	ENSG00000044446	2.19213067732423	[]	[]	3	hSpCas9	negative selection	3543812
18920164	18920187	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGTGGTGAGAAATTCCGAAAGG	PHKA2	ENSG00000044446	0.760686755968318	[]	[]	1	hSpCas9	negative selection	3543813
18926534	18926557	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACTTATTGAGGAAACACGGGG	PHKA2	ENSG00000044446	-0.89349101716722	[]	[]	-1	hSpCas9	negative selection	3543814
18936132	18936155	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGGTCCAAGAATACCGAGAGG	PHKA2	ENSG00000044446	4.17672126423738	[]	[]	7	hSpCas9	negative selection	3543815
18938704	18938727	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGAAGAGCTTGAGTTCAGCAGGG	PHKA2	ENSG00000044446	1.37812345689204	[]	[]	2	hSpCas9	negative selection	3543816
18929274	18929297	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TAAGGGATCGATTTCACCAGCGG	PHKA2	ENSG00000044446	3.07079828161821	[]	[]	5	hSpCas9	negative selection	3543817
18954398	18954421	X	-	26780180	A375	viability (Avana lentiGuide)	TCTAATAGAATCCCGTCACGGGG	PHKA2	ENSG00000044446	-0.378393711522821	[]	[]	0	hSpCas9	negative selection	3652471
18920164	18920187	X	+	26780180	A375	viability (Avana lentiGuide)	ATGTGGTGAGAAATTCCGAAAGG	PHKA2	ENSG00000044446	-5.08629259625543	[]	[]	-8	hSpCas9	negative selection	3652472
18926534	18926557	X	-	26780180	A375	viability (Avana lentiGuide)	GGACTTATTGAGGAAACACGGGG	PHKA2	ENSG00000044446	-0.767454409974939	[]	[]	-1	hSpCas9	negative selection	3652473
18936132	18936155	X	-	26780180	A375	viability (Avana lentiGuide)	CCAGGTCCAAGAATACCGAGAGG	PHKA2	ENSG00000044446	-6.97902236385109	[]	[]	-9	hSpCas9	negative selection	3652474
18938704	18938727	X	+	26780180	A375	viability (Avana lentiGuide)	CGAAGAGCTTGAGTTCAGCAGGG	PHKA2	ENSG00000044446	-9.04122845929268	[]	[]	-9	hSpCas9	negative selection	3652475
18929274	18929297	X	+	26780180	A375	viability (Avana lentiGuide)	TAAGGGATCGATTTCACCAGCGG	PHKA2	ENSG00000044446	0.362842666384912	[]	[]	0	hSpCas9	negative selection	3652476
18954398	18954421	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTAATAGAATCCCGTCACGGGG	PHKA2	ENSG00000044446	-0.21308448402536373	[5]	[5,3]	-3	hSpCas9	positive selection	3761130
18920164	18920187	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGTGGTGAGAAATTCCGAAAGG	PHKA2	ENSG00000044446	-0.05275433478744508	[5]	[5,4]	-1	hSpCas9	positive selection	3761131
18926534	18926557	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACTTATTGAGGAAACACGGGG	PHKA2	ENSG00000044446	-0.6315675691785483	[4]	[3,1]	-7	hSpCas9	positive selection	3761132
18936132	18936155	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGGTCCAAGAATACCGAGAGG	PHKA2	ENSG00000044446	0.31005771757082784	[5]	[7,6]	8	hSpCas9	positive selection	3761133
18938704	18938727	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAAGAGCTTGAGTTCAGCAGGG	PHKA2	ENSG00000044446	0.10098177135601497	[4]	[4,4]	2	hSpCas9	positive selection	3761134
18929274	18929297	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TAAGGGATCGATTTCACCAGCGG	PHKA2	ENSG00000044446	0.07791477139302885	[5]	[5,5]	2	hSpCas9	positive selection	3761135
18954398	18954421	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTAATAGAATCCCGTCACGGGG	PHKA2	ENSG00000044446	-0.14955482011644283	[4]	[2,3]	-2	hSpCas9	positive selection	3869737
18920164	18920187	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGTGGTGAGAAATTCCGAAAGG	PHKA2	ENSG00000044446	0.20342246838246505	[5]	[5,4]	5	hSpCas9	positive selection	3869738
18926534	18926557	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACTTATTGAGGAAACACGGGG	PHKA2	ENSG00000044446	0.19593405597366736	[5]	[4,5]	5	hSpCas9	positive selection	3869739
18936132	18936155	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGGTCCAAGAATACCGAGAGG	PHKA2	ENSG00000044446	0.3199191351128106	[5]	[6,5]	8	hSpCas9	positive selection	3869740
18938704	18938727	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAAGAGCTTGAGTTCAGCAGGG	PHKA2	ENSG00000044446	0.25946176015863937	[4]	[4,5]	7	hSpCas9	positive selection	3869741
18929274	18929297	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TAAGGGATCGATTTCACCAGCGG	PHKA2	ENSG00000044446	0.16357400761299593	[5]	[4,6]	4	hSpCas9	positive selection	3869742
18952519	18952542	X	-	26780180	A375	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.684628811446278	[]	[]	2	hSpCas9	negative selection	3980524
18951203	18951226	X	+	26780180	A375	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	1.00141182781084	[]	[]	4	hSpCas9	negative selection	3980525
18951098	18951121	X	+	26780180	A375	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.436318625464641	[]	[]	1	hSpCas9	negative selection	3980526
18954344	18954367	X	+	26780180	A375	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.924304126795818	[]	[]	4	hSpCas9	negative selection	3980527
18952493	18952516	X	-	26780180	A375	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	0.90320498401001	[]	[]	4	hSpCas9	negative selection	3980528
18954400	18954423	X	-	26780180	A375	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.503782211333895	[]	[]	1	hSpCas9	negative selection	3980529
18952519	18952542	X	-	26780180	HT29	viability (GeCKOv2 library)	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	1.32171020194029	[]	[]	6	hSpCas9	negative selection	4088490
18951203	18951226	X	+	26780180	HT29	viability (GeCKOv2 library)	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	0.97172021284425	[]	[]	4	hSpCas9	negative selection	4088491
18951098	18951121	X	+	26780180	HT29	viability (GeCKOv2 library)	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.775462480544488	[]	[]	3	hSpCas9	negative selection	4088492
18954344	18954367	X	+	26780180	HT29	viability (GeCKOv2 library)	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	1.01188840198019	[]	[]	4	hSpCas9	negative selection	4088493
18952493	18952516	X	-	26780180	HT29	viability (GeCKOv2 library)	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	2.23661484257116	[]	[]	9	hSpCas9	negative selection	4088494
18954400	18954423	X	-	26780180	HT29	viability (GeCKOv2 library)	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	1.36245082622747	[]	[]	7	hSpCas9	negative selection	4088495
18952519	18952542	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.0779122683061427	[3]	[2,2]	2	hSpCas9	positive selection	4160296
18954344	18954367	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	-0.07009456978814307	[3]	[2,2]	-2	hSpCas9	positive selection	4160298
18954301	18954324	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTTACGGTAGGCCATGCCCAGG	PHKA2	ENSG00000044446	0.12797334668873472	[4]	[3,3]	3	hSpCas9	positive selection	4160299
18952519	18952542	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.7800138473985648	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4224318
18954344	18954367	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.9723147849140814	[4]	[4,2,1,3]	6	hSpCas9	positive selection	4224320
18954301	18954324	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTTACGGTAGGCCATGCCCAGG	PHKA2	ENSG00000044446	0.21295088193412087	[3]	[3,2,1,0]	1	hSpCas9	positive selection	4224321
18951203	18951226	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.2665220675856051	[3]	[2,1]	-5	hSpCas9	positive selection	4290054
18954344	18954367	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.6897881863807005	[4]	[4,6]	9	hSpCas9	positive selection	4290055
18954400	18954423	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.03266540918959675	[2]	[2,1]	0	hSpCas9	positive selection	4290056
18951098	18951121	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.06314177072381003	[2]	[2,1]	1	hSpCas9	positive selection	4354306
18952519	18952542	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.9934478696280115	[2]	[3,4]	9	hSpCas9	positive selection	4354307
18952493	18952516	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	0.3946475816236639	[3]	[2,4]	7	hSpCas9	positive selection	4354308
18926472	18926494	X	+	27760321	OCIAML3	viability	ACTAAGAATCCGGCCCGGCTGG	PHKA2	ENSG00000044446	1.1177029717585463	[608,485]	[904,947]	9	hSpCas9	negative selection	4427500
18929280	18929302	X	+	27760321	OCIAML3	viability	ATCGATTTCACCAGCGGCAAGG	PHKA2	ENSG00000044446	0.4649835390378526	[801,624]	[714,829]	5	hSpCas9	negative selection	4427501
18936054	18936076	X	-	27760321	OCIAML3	viability	TACGCTGTCCCGCCTAACAAGG	PHKA2	ENSG00000044446	0.41923987233385207	[719,553]	[517,847]	5	hSpCas9	negative selection	4427502
18941641	18941663	X	+	27760321	OCIAML3	viability	GTCGACGCTCTTGGCAGCATGG	PHKA2	ENSG00000044446	0.4679307939450461	[931,829]	[724,1246]	5	hSpCas9	negative selection	4427503
18954345	18954367	X	+	27760321	OCIAML3	viability	TAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.2671710867092757	[799,618]	[540,821]	3	hSpCas9	negative selection	4427504
18926472	18926494	X	+	27760321	OCIAML2	viability	ACTAAGAATCCGGCCCGGCTGG	PHKA2	ENSG00000044446	0.5430959675108444	[608,485]	[543,769]	7	hSpCas9	negative selection	4510963
18929280	18929302	X	+	27760321	OCIAML2	viability	ATCGATTTCACCAGCGGCAAGG	PHKA2	ENSG00000044446	0.8370240757594448	[801,624]	[903,1181]	9	hSpCas9	negative selection	4510964
18936054	18936076	X	-	27760321	OCIAML2	viability	TACGCTGTCCCGCCTAACAAGG	PHKA2	ENSG00000044446	0.5307144474581227	[719,553]	[687,805]	7	hSpCas9	negative selection	4510965
18941641	18941663	X	+	27760321	OCIAML2	viability	GTCGACGCTCTTGGCAGCATGG	PHKA2	ENSG00000044446	0.8450084567347003	[931,829]	[1106,1503]	9	hSpCas9	negative selection	4510966
18954345	18954367	X	+	27760321	OCIAML2	viability	TAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.4815412855972381	[799,618]	[600,1051]	6	hSpCas9	negative selection	4510967
18926472	18926494	X	+	27760321	MV411	viability	ACTAAGAATCCGGCCCGGCTGG	PHKA2	ENSG00000044446	-0.4218750214939193	[608,485]	[134,467]	-3	hSpCas9	negative selection	4594426
18929280	18929302	X	+	27760321	MV411	viability	ATCGATTTCACCAGCGGCAAGG	PHKA2	ENSG00000044446	1.5650821188090518	[801,624]	[1114,1786]	9	hSpCas9	negative selection	4594427
18936054	18936076	X	-	27760321	MV411	viability	TACGCTGTCCCGCCTAACAAGG	PHKA2	ENSG00000044446	0.3488387213808464	[719,553]	[496,582]	2	hSpCas9	negative selection	4594428
18941641	18941663	X	+	27760321	MV411	viability	GTCGACGCTCTTGGCAGCATGG	PHKA2	ENSG00000044446	0.2551555376862491	[931,829]	[727,639]	1	hSpCas9	negative selection	4594429
18954345	18954367	X	+	27760321	MV411	viability	TAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.24053190763931476	[799,618]	[511,604]	1	hSpCas9	negative selection	4594430
18926472	18926494	X	+	27760321	HL60	viability	ACTAAGAATCCGGCCCGGCTGG	PHKA2	ENSG00000044446	0.3968120090693375	[608,485]	[463,713]	5	hSpCas9	negative selection	4677889
18929280	18929302	X	+	27760321	HL60	viability	ATCGATTTCACCAGCGGCAAGG	PHKA2	ENSG00000044446	0.24892082439998586	[801,624]	[681,693]	3	hSpCas9	negative selection	4677890
18936054	18936076	X	-	27760321	HL60	viability	TACGCTGTCCCGCCTAACAAGG	PHKA2	ENSG00000044446	0.0156328959394898	[719,553]	[492,552]	0	hSpCas9	negative selection	4677891
18941641	18941663	X	+	27760321	HL60	viability	GTCGACGCTCTTGGCAGCATGG	PHKA2	ENSG00000044446	0.04474790245914262	[931,829]	[732,749]	0	hSpCas9	negative selection	4677892
18954345	18954367	X	+	27760321	HL60	viability	TAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.3630995584277392	[799,618]	[659,824]	4	hSpCas9	negative selection	4677893
18926472	18926494	X	+	27760321	HT1080	viability	ACTAAGAATCCGGCCCGGCTGG	PHKA2	ENSG00000044446	1.5835434780046893	[485,378]	[586,438]	8	hSpCas9	negative selection	4761352
18929280	18929302	X	+	27760321	HT1080	viability	ATCGATTTCACCAGCGGCAAGG	PHKA2	ENSG00000044446	0.4114471182943368	[624,487]	[291,297]	2	hSpCas9	negative selection	4761353
18936054	18936076	X	-	27760321	HT1080	viability	TACGCTGTCCCGCCTAACAAGG	PHKA2	ENSG00000044446	1.2546120756896348	[553,432]	[534,396]	6	hSpCas9	negative selection	4761354
18941641	18941663	X	+	27760321	HT1080	viability	GTCGACGCTCTTGGCAGCATGG	PHKA2	ENSG00000044446	0.9508360185586231	[829,647]	[654,474]	5	hSpCas9	negative selection	4761355
18954345	18954367	X	+	27760321	HT1080	viability	TAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	1.036848464572513	[618,482]	[499,395]	5	hSpCas9	negative selection	4761356
18926472	18926494	X	+	27760321	HT29	viability after 7 days	ACTAAGAATCCGGCCCGGCTGG	PHKA2	ENSG00000044446	0.39296664384490565	[485,378]	[764,561,862]	6	hSpCas9	negative selection	4844815
18929280	18929302	X	+	27760321	HT29	viability after 7 days	ATCGATTTCACCAGCGGCAAGG	PHKA2	ENSG00000044446	0.26268220837709855	[624,487]	[947,914,727]	4	hSpCas9	negative selection	4844816
18936054	18936076	X	-	27760321	HT29	viability after 7 days	TACGCTGTCCCGCCTAACAAGG	PHKA2	ENSG00000044446	0.23784185940441716	[553,432]	[510,602,1084]	3	hSpCas9	negative selection	4844817
18941641	18941663	X	+	27760321	HT29	viability after 7 days	GTCGACGCTCTTGGCAGCATGG	PHKA2	ENSG00000044446	0.26769758831281876	[829,647]	[1263,1098,1085]	4	hSpCas9	negative selection	4844818
18954345	18954367	X	+	27760321	HT29	viability after 7 days	TAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.0025575666799767527	[618,482]	[762,484,881]	0	hSpCas9	negative selection	4844819
18926472	18926494	X	+	27760321	HT29	viability after 25 days	ACTAAGAATCCGGCCCGGCTGG	PHKA2	ENSG00000044446	0.48495422637057795	[485,378]	[536,603,971]	5	hSpCas9	negative selection	4928278
18929280	18929302	X	+	27760321	HT29	viability after 25 days	ATCGATTTCACCAGCGGCAAGG	PHKA2	ENSG00000044446	0.516049390574466	[624,487]	[1020,867,821]	5	hSpCas9	negative selection	4928279
18936054	18936076	X	-	27760321	HT29	viability after 25 days	TACGCTGTCCCGCCTAACAAGG	PHKA2	ENSG00000044446	0.8004712044034122	[553,432]	[936,1032,977]	8	hSpCas9	negative selection	4928280
18941641	18941663	X	+	27760321	HT29	viability after 25 days	GTCGACGCTCTTGGCAGCATGG	PHKA2	ENSG00000044446	0.5238910409642015	[829,647]	[1172,1176,1302]	6	hSpCas9	negative selection	4928281
18954345	18954367	X	+	27760321	HT29	viability after 25 days	TAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.30942757601057036	[618,482]	[528,792,1062]	3	hSpCas9	negative selection	4928282
18926472	18926494	X	+	27760321	HT29	viability after 22 days	ACTAAGAATCCGGCCCGGCTGG	PHKA2	ENSG00000044446	0.5663142954052162	[485,378]	[832,688,695]	6	hSpCas9	negative selection	5011741
18929280	18929302	X	+	27760321	HT29	viability after 22 days	ATCGATTTCACCAGCGGCAAGG	PHKA2	ENSG00000044446	0.3683521109229755	[624,487]	[955,812,717]	4	hSpCas9	negative selection	5011742
18936054	18936076	X	-	27760321	HT29	viability after 22 days	TACGCTGTCCCGCCTAACAAGG	PHKA2	ENSG00000044446	0.781191060274718	[553,432]	[912,1195,832]	8	hSpCas9	negative selection	5011743
18941641	18941663	X	+	27760321	HT29	viability after 22 days	GTCGACGCTCTTGGCAGCATGG	PHKA2	ENSG00000044446	0.4497370629270745	[829,647]	[991,846,1670]	5	hSpCas9	negative selection	5011744
18954345	18954367	X	+	27760321	HT29	viability after 22 days	TAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.04257743847868478	[618,482]	[684,662,618]	0	hSpCas9	negative selection	5011745
18926472	18926494	X	+	27760321	HT29	viability after 19 days	ACTAAGAATCCGGCCCGGCTGG	PHKA2	ENSG00000044446	0.7029151567715719	[485,378]	[791,776,842]	7	hSpCas9	negative selection	5095204
18929280	18929302	X	+	27760321	HT29	viability after 19 days	ATCGATTTCACCAGCGGCAAGG	PHKA2	ENSG00000044446	0.49782910578365647	[624,487]	[949,958,795]	5	hSpCas9	negative selection	5095205
18936054	18936076	X	-	27760321	HT29	viability after 19 days	TACGCTGTCCCGCCTAACAAGG	PHKA2	ENSG00000044446	0.6776518739641754	[553,432]	[949,915,848]	7	hSpCas9	negative selection	5095206
18941641	18941663	X	+	27760321	HT29	viability after 19 days	GTCGACGCTCTTGGCAGCATGG	PHKA2	ENSG00000044446	0.2791453006046001	[829,647]	[862,978,1209]	2	hSpCas9	negative selection	5095207
18954345	18954367	X	+	27760321	HT29	viability after 19 days	TAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.36877347023324325	[618,482]	[1009,688,763]	3	hSpCas9	negative selection	5095208
18926472	18926494	X	+	27760321	HT29	viability after 16 days	ACTAAGAATCCGGCCCGGCTGG	PHKA2	ENSG00000044446	0.7471502539075056	[485,378]	[742,879,804]	8	hSpCas9	negative selection	5178667
18929280	18929302	X	+	27760321	HT29	viability after 16 days	ATCGATTTCACCAGCGGCAAGG	PHKA2	ENSG00000044446	0.260014488553272	[624,487]	[828,957,451]	3	hSpCas9	negative selection	5178668
18936054	18936076	X	-	27760321	HT29	viability after 16 days	TACGCTGTCCCGCCTAACAAGG	PHKA2	ENSG00000044446	0.719625965027287	[553,432]	[855,898,967]	8	hSpCas9	negative selection	5178669
18941641	18941663	X	+	27760321	HT29	viability after 16 days	GTCGACGCTCTTGGCAGCATGG	PHKA2	ENSG00000044446	0.47125333361067434	[829,647]	[1278,1108,1063]	5	hSpCas9	negative selection	5178670
18954345	18954367	X	+	27760321	HT29	viability after 16 days	TAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.14727614318897464	[618,482]	[554,718,760]	1	hSpCas9	negative selection	5178671
18926472	18926494	X	+	27760321	HT29	viability after 13 days	ACTAAGAATCCGGCCCGGCTGG	PHKA2	ENSG00000044446	0.5313597888293204	[485,378]	[736,640,792]	6	hSpCas9	negative selection	5262130
18929280	18929302	X	+	27760321	HT29	viability after 13 days	ATCGATTTCACCAGCGGCAAGG	PHKA2	ENSG00000044446	0.2644877171494918	[624,487]	[933,683,711]	3	hSpCas9	negative selection	5262131
18936054	18936076	X	-	27760321	HT29	viability after 13 days	TACGCTGTCCCGCCTAACAAGG	PHKA2	ENSG00000044446	0.5618099326435527	[553,432]	[740,853,934]	7	hSpCas9	negative selection	5262132
18941641	18941663	X	+	27760321	HT29	viability after 13 days	GTCGACGCTCTTGGCAGCATGG	PHKA2	ENSG00000044446	0.13542986989215433	[829,647]	[947,901,972]	1	hSpCas9	negative selection	5262133
18954345	18954367	X	+	27760321	HT29	viability after 13 days	TAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	-0.15863678845985824	[618,482]	[547,598,570]	-2	hSpCas9	negative selection	5262134
18926472	18926494	X	+	27760321	HT29	viability after 10 days	ACTAAGAATCCGGCCCGGCTGG	PHKA2	ENSG00000044446	0.3424766399225837	[485,378]	[691,824,543]	4	hSpCas9	negative selection	5345593
18929280	18929302	X	+	27760321	HT29	viability after 10 days	ATCGATTTCACCAGCGGCAAGG	PHKA2	ENSG00000044446	0.281163973968908	[624,487]	[836,688,998]	4	hSpCas9	negative selection	5345594
18936054	18936076	X	-	27760321	HT29	viability after 10 days	TACGCTGTCCCGCCTAACAAGG	PHKA2	ENSG00000044446	0.44136408177810016	[553,432]	[594,1182,743]	6	hSpCas9	negative selection	5345595
18941641	18941663	X	+	27760321	HT29	viability after 10 days	GTCGACGCTCTTGGCAGCATGG	PHKA2	ENSG00000044446	0.09958639974142525	[829,647]	[812,1111,1042]	1	hSpCas9	negative selection	5345596
18954345	18954367	X	+	27760321	HT29	viability after 10 days	TAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	-0.0825959160572386	[618,482]	[520,949,489]	-1	hSpCas9	negative selection	5345597
18926472	18926494	X	+	27760321	MOLM13	viability	ACTAAGAATCCGGCCCGGCTGG	PHKA2	ENSG00000044446	1.7165593485046964	[608,485]	[1322,741]	9	hSpCas9	negative selection	5429056
18929280	18929302	X	+	27760321	MOLM13	viability	ATCGATTTCACCAGCGGCAAGG	PHKA2	ENSG00000044446	-0.08549628172967638	[801,624]	[399,356]	0	hSpCas9	negative selection	5429057
18936054	18936076	X	-	27760321	MOLM13	viability	TACGCTGTCCCGCCTAACAAGG	PHKA2	ENSG00000044446	0.4572882641364804	[719,553]	[512,469]	3	hSpCas9	negative selection	5429058
18941641	18941663	X	+	27760321	MOLM13	viability	GTCGACGCTCTTGGCAGCATGG	PHKA2	ENSG00000044446	0.8187668761734401	[931,829]	[848,897]	6	hSpCas9	negative selection	5429059
18954345	18954367	X	+	27760321	MOLM13	viability	TAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	2.216159889781835	[799,618]	[3162,725]	9	hSpCas9	negative selection	5429060
18983677	18983700	X	+	27661255	K562	viability	GAATCTTAAGGAGCACGGGGTGG	PHKA2	ENSG00000044446	-1.1264668974769318	[473,424]	[214,121]	-8	dCas9-KRAB	negative selection	5501615
18983698	18983721	X	+	27661255	K562	viability	GGCAATGGGGTGGTAATCACTGG	PHKA2	ENSG00000044446	0.1852447544554729	[874,774]	[832,680]	6	dCas9-KRAB	negative selection	5501616
18983770	18983793	X	+	27661255	K562	viability	GTCACAAGAGGGCCAGACCTGGG	PHKA2	ENSG00000044446	0.20552050293558655	[1251,1614]	[1518,1139]	7	dCas9-KRAB	negative selection	5501617
18984340	18984363	X	-	27661255	K562	viability	GGCCTGGGCGATCTCCCCGGCGG	PHKA2	ENSG00000044446	0.10324691540879372	[710,975]	[865,594]	3	dCas9-KRAB	negative selection	5501618
18951203	18951226	X	+	27260156	BXPC3	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.10893411288230576	[605]	[472,615,611,665]	-3	hSpCas9	negative selection	5562514
18954344	18954367	X	+	27260156	BXPC3	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.28097259460983914	[1228]	[1530,1583,1319,1829]	6	hSpCas9	negative selection	5562515
18954400	18954423	X	-	27260156	BXPC3	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.1376676997964568	[418]	[596,451,336,530]	3	hSpCas9	negative selection	5562516
18951098	18951121	X	+	27260156	BXPC3	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.12824042057324198	[440]	[479,444,466,642]	3	hSpCas9	negative selection	5626766
18952519	18952542	X	-	27260156	BXPC3	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.1688229253683151	[286]	[162,210,366,351]	-4	hSpCas9	negative selection	5626767
18952493	18952516	X	-	27260156	BXPC3	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.17854194905843238	[602]	[443,591,603,600]	-4	hSpCas9	negative selection	5626768
18951203	18951226	X	+	27260156	A673	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.2396523859591801	[605]	[700,528,582,665]	-5	hSpCas9	negative selection	5683765
18954344	18954367	X	+	27260156	A673	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.1396553443516877	[1228]	[1620,1570,1548,1767]	3	hSpCas9	negative selection	5683766
18954400	18954423	X	-	27260156	A673	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.06688137763108196	[418]	[578,508,477,548]	1	hSpCas9	negative selection	5683767
18951098	18951121	X	+	27260156	A673	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.035963385215953936	[440]	[629,441,566,543]	0	hSpCas9	negative selection	5748017
18952519	18952542	X	-	27260156	A673	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.1482480987973226	[286]	[542,289,395,314]	3	hSpCas9	negative selection	5748018
18952493	18952516	X	-	27260156	A673	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.18385630358633281	[602]	[782,677,636,455]	-4	hSpCas9	negative selection	5748019
18951203	18951226	X	+	27260156	A375	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.04038977521734599	[605]	[696,862,639,586]	0	hSpCas9	negative selection	5805016
18954344	18954367	X	+	27260156	A375	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.43844185732310814	[1228]	[2115,2012,1616,2027]	6	hSpCas9	negative selection	5805017
18954400	18954423	X	-	27260156	A375	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.1261344485298987	[418]	[520,598,606,428]	1	hSpCas9	negative selection	5805018
18951098	18951121	X	+	27260156	A375	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.4298909757428118	[440]	[590,953,677,596]	6	hSpCas9	negative selection	5869268
18952519	18952542	X	-	27260156	A375	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.16752216089653393	[286]	[465,361,352,327]	2	hSpCas9	negative selection	5869269
18952493	18952516	X	-	27260156	A375	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	0.1937704026314523	[602]	[766,831,1081,569]	3	hSpCas9	negative selection	5869270
18951203	18951226	X	+	27260156	COLO741	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.13070996577030927	[605]	[622,641,837]	-3	hSpCas9	negative selection	5926267
18954344	18954367	X	+	27260156	COLO741	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.12116095902741186	[1228]	[1732,1654,1731]	2	hSpCas9	negative selection	5926268
18954400	18954423	X	-	27260156	COLO741	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	-0.2181846906329095	[418]	[486,408,483]	-5	hSpCas9	negative selection	5926269
18951098	18951121	X	+	27260156	COLO741	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	-0.18837501805271378	[440]	[582,499,412]	-4	hSpCas9	negative selection	5990519
18952519	18952542	X	-	27260156	COLO741	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.07748069881358399	[286]	[484,273,297]	-2	hSpCas9	negative selection	5990520
18952493	18952516	X	-	27260156	COLO741	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.06000127354465501	[602]	[797,760,666]	-1	hSpCas9	negative selection	5990521
18951203	18951226	X	+	27260156	CAL120	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.3559310904835436	[605]	[663,598,516]	-5	hSpCas9	negative selection	6047518
18954344	18954367	X	+	27260156	CAL120	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.20290754865513083	[1228]	[2062,1684,1580]	3	hSpCas9	negative selection	6047519
18954400	18954423	X	-	27260156	CAL120	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	-0.4725605505671958	[418]	[530,383,237]	-6	hSpCas9	negative selection	6047520
18951098	18951121	X	+	27260156	CAL120	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.3403941331020362	[440]	[540,825,693]	5	hSpCas9	negative selection	6111770
18952519	18952542	X	-	27260156	CAL120	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.21110680136579152	[286]	[218,385,306]	-3	hSpCas9	negative selection	6111771
18952493	18952516	X	-	27260156	CAL120	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.13151622253573847	[602]	[633,559,849]	-2	hSpCas9	negative selection	6111772
18951203	18951226	X	+	27260156	CADOES1	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.16895127141238175	[605]	[640,428,530,399]	-3	hSpCas9	negative selection	6168769
18954344	18954367	X	+	27260156	CADOES1	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.17163534501523414	[1228]	[1182,1448,1393,1117]	3	hSpCas9	negative selection	6168770
18954400	18954423	X	-	27260156	CADOES1	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.05055847460741707	[418]	[390,459,347,415]	0	hSpCas9	negative selection	6168771
18951098	18951121	X	+	27260156	CADOES1	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.22908241776116323	[440]	[360,520,466,577]	4	hSpCas9	negative selection	6233021
18952519	18952542	X	-	27260156	CADOES1	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.2565496854853777	[286]	[328,223,409,311]	4	hSpCas9	negative selection	6233022
18952493	18952516	X	-	27260156	CADOES1	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.0767423015242587	[602]	[495,469,629,530]	-1	hSpCas9	negative selection	6233023
18951203	18951226	X	+	27260156	EWS502	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.12259515508441138	[605]	[423,792,518,633]	-2	hSpCas9	negative selection	6290020
18954344	18954367	X	+	27260156	EWS502	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.17949278490415854	[1228]	[1322,1434,1566,1595]	3	hSpCas9	negative selection	6290021
18954400	18954423	X	-	27260156	EWS502	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	-0.1271805179415367	[418]	[400,260,428,549]	-2	hSpCas9	negative selection	6290022
18951098	18951121	X	+	27260156	EWS502	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.24850204700787587	[440]	[572,628,450,557]	4	hSpCas9	negative selection	6354272
18952519	18952542	X	-	27260156	EWS502	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.08117471314662117	[286]	[230,356,246,318]	-1	hSpCas9	negative selection	6354273
18952493	18952516	X	-	27260156	EWS502	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.11091121253942784	[602]	[576,552,749,480]	-2	hSpCas9	negative selection	6354274
18951203	18951226	X	+	27260156	EW8	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.23309769823545456	[605]	[484,456,255,506]	-4	hSpCas9	negative selection	6411271
18954344	18954367	X	+	27260156	EW8	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.25295271316518386	[1228]	[1278,1067,1045,1383]	4	hSpCas9	negative selection	6411272
18954400	18954423	X	-	27260156	EW8	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	-0.01841720086202084	[418]	[401,469,284,199]	0	hSpCas9	negative selection	6411273
18951098	18951121	X	+	27260156	EW8	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.20287805648391333	[440]	[487,591,220,384]	4	hSpCas9	negative selection	6475523
18952519	18952542	X	-	27260156	EW8	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.15066565413978905	[286]	[190,211,229,198]	-3	hSpCas9	negative selection	6475524
18952493	18952516	X	-	27260156	EW8	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.06971267914355539	[602]	[474,424,452,510]	-1	hSpCas9	negative selection	6475525
18951203	18951226	X	+	27260156	CORL105	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.10421798660289255	[605]	[816,502,789,558]	-2	hSpCas9	negative selection	6532522
18954344	18954367	X	+	27260156	CORL105	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.291166157916686	[1228]	[1606,1693,2031,1746]	5	hSpCas9	negative selection	6532523
18954400	18954423	X	-	27260156	CORL105	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.05471982363618165	[418]	[440,507,589,508]	1	hSpCas9	negative selection	6532524
18951098	18951121	X	+	27260156	CORL105	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.2805519418336848	[440]	[507,610,671,719]	5	hSpCas9	negative selection	6596774
18952519	18952542	X	-	27260156	CORL105	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.44785580362103367	[286]	[471,423,507,437]	7	hSpCas9	negative selection	6596775
18952493	18952516	X	-	27260156	CORL105	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.006736746403176397	[602]	[745,402,1073,652]	0	hSpCas9	negative selection	6596776
18951203	18951226	X	+	27260156	HS294T	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.11163566038051398	[605]	[191,187,243,251]	-1	hSpCas9	negative selection	6653773
18954344	18954367	X	+	27260156	HS294T	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.38171569835997277	[1228]	[536,485,534,990]	5	hSpCas9	negative selection	6653774
18954400	18954423	X	-	27260156	HS294T	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.06789816503843328	[418]	[214,110,186,161]	0	hSpCas9	negative selection	6653775
18951098	18951121	X	+	27260156	HS294T	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	-0.13593225010088206	[440]	[161,135,162,159]	-2	hSpCas9	negative selection	6718025
18952519	18952542	X	-	27260156	HS294T	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.14646821300048374	[286]	[108,98,90,100]	-2	hSpCas9	negative selection	6718026
18952493	18952516	X	-	27260156	HS294T	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	0.3839245054915136	[602]	[389,260,203,363]	5	hSpCas9	negative selection	6718027
18951203	18951226	X	+	27260156	HCC44	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.2537051520464871	[605]	[895,494,418,500]	-4	hSpCas9	negative selection	6775024
18954344	18954367	X	+	27260156	HCC44	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.24200328780214542	[1228]	[1589,1144,2102,1861]	4	hSpCas9	negative selection	6775025
18954400	18954423	X	-	27260156	HCC44	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.09422231827705393	[418]	[547,392,618,498]	1	hSpCas9	negative selection	6775026
18951098	18951121	X	+	27260156	HCC44	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.037960081686061325	[440]	[730,310,607,460]	0	hSpCas9	negative selection	6839276
18952519	18952542	X	-	27260156	HCC44	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.3240309295014574	[286]	[343,208,270,228]	-5	hSpCas9	negative selection	6839277
18952493	18952516	X	-	27260156	HCC44	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	0.060068105953368756	[602]	[609,961,552,642]	0	hSpCas9	negative selection	6839278
18951203	18951226	X	+	27260156	G402	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.4889378483853272	[605]	[944,347,409,455]	-6	hSpCas9	negative selection	6896275
18954344	18954367	X	+	27260156	G402	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.12137180629342326	[1228]	[1648,1454,1839,1569]	1	hSpCas9	negative selection	6896276
18954400	18954423	X	-	27260156	G402	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	-0.13987347628175542	[418]	[570,543,371,390]	-2	hSpCas9	negative selection	6896277
18951098	18951121	X	+	27260156	G402	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.3361072647120744	[440]	[537,650,920,586]	4	hSpCas9	negative selection	6960527
18952519	18952542	X	-	27260156	G402	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.40394889707596565	[286]	[314,790,401,346]	5	hSpCas9	negative selection	6960528
18952493	18952516	X	-	27260156	G402	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.09525053279030082	[602]	[990,533,677,588]	-1	hSpCas9	negative selection	6960529
18951203	18951226	X	+	27260156	L33	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.1572041840411635	[605]	[502,203,383,562]	-4	hSpCas9	negative selection	7017526
18954344	18954367	X	+	27260156	L33	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.09151230156233403	[1228]	[1279,490,960,1232]	2	hSpCas9	negative selection	7017527
18954400	18954423	X	-	27260156	L33	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.08077041560699912	[418]	[406,183,287,458]	1	hSpCas9	negative selection	7017528
18951098	18951121	X	+	27260156	L33	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	-0.0473144506108243	[440]	[458,184,258,383]	-1	hSpCas9	negative selection	7081778
18952519	18952542	X	-	27260156	L33	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.016937598350702743	[286]	[274,130,135,322]	0	hSpCas9	negative selection	7081779
18952493	18952516	X	-	27260156	L33	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.4000379171490576	[602]	[406,204,258,508]	-7	hSpCas9	negative selection	7081780
18951203	18951226	X	+	27260156	K562	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	0.32034588657816465	[605]	[754,593,496,821]	4	hSpCas9	negative selection	7138777
18954344	18954367	X	+	27260156	K562	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.4014594012587045	[1228]	[1163,1576,1118,1833]	5	hSpCas9	negative selection	7138778
18954400	18954423	X	-	27260156	K562	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.23150303052417523	[418]	[528,345,386,479]	3	hSpCas9	negative selection	7138779
18951098	18951121	X	+	27260156	K562	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.4285284404377058	[440]	[241,590,548,683]	5	hSpCas9	negative selection	7203029
18952519	18952542	X	-	27260156	K562	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.5771239806834925	[286]	[270,387,359,478]	7	hSpCas9	negative selection	7203030
18952493	18952516	X	-	27260156	K562	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.36367257395881664	[602]	[266,429,458,485]	-4	hSpCas9	negative selection	7203031
18951203	18951226	X	+	27260156	HT29	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.1569829005598854	[605]	[514,908,669,565]	-3	hSpCas9	negative selection	7260028
18954344	18954367	X	+	27260156	HT29	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.16092675067953688	[1228]	[1816,1519,1728,1608]	3	hSpCas9	negative selection	7260029
18954400	18954423	X	-	27260156	HT29	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.16371721899604813	[418]	[481,544,724,522]	3	hSpCas9	negative selection	7260030
18951098	18951121	X	+	27260156	HT29	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.06663190052688314	[440]	[572,545,639,490]	1	hSpCas9	negative selection	7324280
18952519	18952542	X	-	27260156	HT29	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.01179517089872939	[286]	[464,377,333,250]	0	hSpCas9	negative selection	7324281
18952493	18952516	X	-	27260156	HT29	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.01559956013883429	[602]	[830,597,814,656]	0	hSpCas9	negative selection	7324282
18951203	18951226	X	+	27260156	MHHES1	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.09288370683901193	[605]	[944,691,586,415]	-2	hSpCas9	negative selection	7381279
18954344	18954367	X	+	27260156	MHHES1	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.3133948045011421	[1228]	[2350,1952,1383,1339]	5	hSpCas9	negative selection	7381280
18954400	18954423	X	-	27260156	MHHES1	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.14226864215240762	[418]	[841,517,526,279]	2	hSpCas9	negative selection	7381281
18951098	18951121	X	+	27260156	MHHES1	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.2476466882077794	[440]	[686,744,460,499]	4	hSpCas9	negative selection	7445531
18952519	18952542	X	-	27260156	MHHES1	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.1990257639332934	[286]	[313,326,261,235]	-4	hSpCas9	negative selection	7445532
18952493	18952516	X	-	27260156	MHHES1	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	0.3716155196806642	[602]	[1433,1012,443,718]	6	hSpCas9	negative selection	7445533
18951203	18951226	X	+	27260156	MEWO	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.4036756140367689	[605]	[655,364,308]	-7	hSpCas9	negative selection	7502530
18954344	18954367	X	+	27260156	MEWO	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	-0.08232819171468608	[1228]	[1380,1083,849]	-2	hSpCas9	negative selection	7502531
18954400	18954423	X	-	27260156	MEWO	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	-0.14740510828994322	[418]	[450,252,376]	-3	hSpCas9	negative selection	7502532
18951098	18951121	X	+	27260156	MEWO	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.03452954560025371	[440]	[622,312,370]	0	hSpCas9	negative selection	7566782
18952519	18952542	X	-	27260156	MEWO	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.1294830712812317	[286]	[196,230,298]	-3	hSpCas9	negative selection	7566783
18952493	18952516	X	-	27260156	MEWO	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.12997251577627245	[602]	[637,563,367]	-3	hSpCas9	negative selection	7566784
18951203	18951226	X	+	27260156	LNCAPCLONEFGC	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.006033772691348638	[605]	[526,425,528,709]	0	hSpCas9	negative selection	7623781
18954344	18954367	X	+	27260156	LNCAPCLONEFGC	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.31265578546190165	[1228]	[1187,1424,1787,1189]	5	hSpCas9	negative selection	7623782
18954400	18954423	X	-	27260156	LNCAPCLONEFGC	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.26297965413718316	[418]	[517,479,403,408]	4	hSpCas9	negative selection	7623783
18951098	18951121	X	+	27260156	LNCAPCLONEFGC	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.08849404561179663	[440]	[374,413,448,465]	1	hSpCas9	negative selection	7688033
18952519	18952542	X	-	27260156	LNCAPCLONEFGC	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.061633598117321386	[286]	[266,165,306,269]	-1	hSpCas9	negative selection	7688034
18952493	18952516	X	-	27260156	LNCAPCLONEFGC	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	0.09346010790892001	[602]	[721,421,712,500]	1	hSpCas9	negative selection	7688035
18951203	18951226	X	+	27260156	PANC0327	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	0.030293723794607097	[605]	[1012,414,402,422]	0	hSpCas9	negative selection	7745032
18954344	18954367	X	+	27260156	PANC0327	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.28578113615937095	[1228]	[1371,1396,1290,1257]	4	hSpCas9	negative selection	7745033
18954400	18954423	X	-	27260156	PANC0327	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.351261930868566	[418]	[563,290,454,619]	5	hSpCas9	negative selection	7745034
18951098	18951121	X	+	27260156	PANC0327	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.17990834333002975	[440]	[523,301,537,435]	2	hSpCas9	negative selection	7809284
18952519	18952542	X	-	27260156	PANC0327	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.0890738764448159	[286]	[237,159,198,498]	1	hSpCas9	negative selection	7809285
18952493	18952516	X	-	27260156	PANC0327	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.0694060026561395	[602]	[406,559,550,508]	-1	hSpCas9	negative selection	7809286
18951203	18951226	X	+	27260156	NCIH2009	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.1931768660548732	[605]	[1005,790,474]	-3	hSpCas9	negative selection	7866283
18954344	18954367	X	+	27260156	NCIH2009	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.31315941057970664	[1228]	[2967,1773,1825]	4	hSpCas9	negative selection	7866284
18954400	18954423	X	-	27260156	NCIH2009	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.4196876325502812	[418]	[1144,584,692]	6	hSpCas9	negative selection	7866285
18951098	18951121	X	+	27260156	NCIH2009	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.20811811981863818	[440]	[790,641,717]	3	hSpCas9	negative selection	7930535
18952519	18952542	X	-	27260156	NCIH2009	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.19308181649111444	[286]	[519,326,541]	2	hSpCas9	negative selection	7930536
18952493	18952516	X	-	27260156	NCIH2009	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	0.26713330149754855	[602]	[1017,1050,970]	3	hSpCas9	negative selection	7930537
18951203	18951226	X	+	27260156	NCIH1373	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	0.022432054108944055	[605]	[889,663,654,150]	0	hSpCas9	negative selection	7987534
18954344	18954367	X	+	27260156	NCIH1373	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.7765053247178284	[1228]	[3419,2017,1355,758]	7	hSpCas9	negative selection	7987535
18954400	18954423	X	-	27260156	NCIH1373	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.5363935003343273	[418]	[599,508,423,323]	5	hSpCas9	negative selection	7987536
18951098	18951121	X	+	27260156	NCIH1373	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.2828742983359591	[440]	[660,541,700,132]	2	hSpCas9	negative selection	8051786
18952519	18952542	X	-	27260156	NCIH1373	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.33231293173753723	[286]	[715,293,281,101]	3	hSpCas9	negative selection	8051787
18952493	18952516	X	-	27260156	NCIH1373	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	0.48561120048027917	[602]	[756,986,1041,251]	5	hSpCas9	negative selection	8051788
18951203	18951226	X	+	27260156	PATU8902	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	0.6025135683502243	[605]	[1284,1245,1288,1294]	6	hSpCas9	negative selection	8108785
18954344	18954367	X	+	27260156	PATU8902	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.7093390650986215	[1228]	[3462,3410,1493,3181]	7	hSpCas9	negative selection	8108786
18954400	18954423	X	-	27260156	PATU8902	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.3096342028087788	[418]	[691,642,900,588]	3	hSpCas9	negative selection	8108787
18951098	18951121	X	+	27260156	PATU8902	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.8031191314330918	[440]	[780,864,1152,1513]	8	hSpCas9	negative selection	8173037
18952519	18952542	X	-	27260156	PATU8902	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.5981793160186377	[286]	[801,757,105,913]	6	hSpCas9	negative selection	8173038
18952493	18952516	X	-	27260156	PATU8902	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	0.29957009473450547	[602]	[675,1269,1266,833]	3	hSpCas9	negative selection	8173039
18951203	18951226	X	+	27260156	PANC1	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	0.10429139928632081	[605]	[543,835,522,407]	1	hSpCas9	negative selection	8230036
18954344	18954367	X	+	27260156	PANC1	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.22861155859397808	[1228]	[999,1488,1305,1195]	3	hSpCas9	negative selection	8230037
18954400	18954423	X	-	27260156	PANC1	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.17132865121944568	[418]	[378,631,421,253]	2	hSpCas9	negative selection	8230038
18951098	18951121	X	+	27260156	PANC1	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.05801931701103192	[440]	[420,458,409,307]	0	hSpCas9	negative selection	8294288
18952519	18952542	X	-	27260156	PANC1	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.2763893045097421	[286]	[99,236,289,194]	-4	hSpCas9	negative selection	8294289
18952493	18952516	X	-	27260156	PANC1	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.09357974603435837	[602]	[593,562,491,324]	-1	hSpCas9	negative selection	8294290
18951203	18951226	X	+	27260156	PANC0813	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.03285050588539251	[605]	[795,726,593,674]	0	hSpCas9	negative selection	8351287
18954344	18954367	X	+	27260156	PANC0813	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.39922626307017106	[1228]	[2059,1665,2111,1795]	6	hSpCas9	negative selection	8351288
18954400	18954423	X	-	27260156	PANC0813	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.6362141137808662	[418]	[909,738,820,610]	8	hSpCas9	negative selection	8351289
18951098	18951121	X	+	27260156	PANC0813	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.5626209523625257	[440]	[663,754,810,816]	8	hSpCas9	negative selection	8415539
18952519	18952542	X	-	27260156	PANC0813	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.09453094466596357	[286]	[351,391,242,445]	1	hSpCas9	negative selection	8415540
18952493	18952516	X	-	27260156	PANC0813	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.17682569189170813	[602]	[941,514,505,573]	-3	hSpCas9	negative selection	8415541
18951203	18951226	X	+	27260156	RDES	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	0.04688605479867197	[605]	[497,798,812,805]	0	hSpCas9	negative selection	8472538
18954344	18954367	X	+	27260156	RDES	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.33551462772693674	[1228]	[1486,1763,1827,2117]	5	hSpCas9	negative selection	8472539
18954400	18954423	X	-	27260156	RDES	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	-0.11072014131506505	[418]	[339,452,458,559]	-2	hSpCas9	negative selection	8472540
18951098	18951121	X	+	27260156	RDES	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.09837251644107478	[440]	[352,477,681,724]	1	hSpCas9	negative selection	8536790
18952519	18952542	X	-	27260156	RDES	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.07317452336564867	[286]	[324,321,401,335]	1	hSpCas9	negative selection	8536791
18952493	18952516	X	-	27260156	RDES	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.15401700244114697	[602]	[537,532,747,697]	-3	hSpCas9	negative selection	8536792
18951203	18951226	X	+	27260156	PC3	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.39179956081297096	[605]	[211,405,686,713]	-7	hSpCas9	negative selection	8593789
18954344	18954367	X	+	27260156	PC3	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.18188685032305618	[1228]	[912,1691,1894,1297]	4	hSpCas9	negative selection	8593790
18954400	18954423	X	-	27260156	PC3	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.347040524828919	[418]	[342,530,664,672]	7	hSpCas9	negative selection	8593791
18951098	18951121	X	+	27260156	PC3	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	-0.04918629902891404	[440]	[239,460,687,454]	-1	hSpCas9	negative selection	8658041
18952519	18952542	X	-	27260156	PC3	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.023075248898359213	[286]	[257,316,452,165]	0	hSpCas9	negative selection	8658042
18952493	18952516	X	-	27260156	PC3	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.2356819279430492	[602]	[289,501,915,544]	-5	hSpCas9	negative selection	8658043
18951203	18951226	X	+	27260156	PATU8988T	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.13264951817163853	[605]	[651,528,495,452]	-2	hSpCas9	negative selection	8715040
18954344	18954367	X	+	27260156	PATU8988T	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.11712104668139167	[1228]	[1054,1500,1465,1134]	2	hSpCas9	negative selection	8715041
18954400	18954423	X	-	27260156	PATU8988T	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	-0.03810003383160945	[418]	[396,426,310,450]	0	hSpCas9	negative selection	8715042
18951098	18951121	X	+	27260156	PATU8988T	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.17334753041982381	[440]	[357,811,368,409]	3	hSpCas9	negative selection	8779292
18952519	18952542	X	-	27260156	PATU8988T	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.18327646766315575	[286]	[394,460,164,248]	3	hSpCas9	negative selection	8779293
18952493	18952516	X	-	27260156	PATU8988T	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.3912007527858125	[602]	[414,416,338,618]	-6	hSpCas9	negative selection	8779294
18951203	18951226	X	+	27260156	T47D	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.11875854390221485	[605]	[730,553,610,715]	-3	hSpCas9	negative selection	8836291
18954344	18954367	X	+	27260156	T47D	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.17859754742926492	[1228]	[1491,1626,1601,1763]	4	hSpCas9	negative selection	8836292
18954400	18954423	X	-	27260156	T47D	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.04137141976752126	[418]	[538,430,458,589]	0	hSpCas9	negative selection	8836293
18951098	18951121	X	+	27260156	T47D	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	-0.07802381393258269	[440]	[477,399,518,558]	-2	hSpCas9	negative selection	8900543
18952519	18952542	X	-	27260156	T47D	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.03197702985874806	[286]	[423,247,350,352]	0	hSpCas9	negative selection	8900544
18952493	18952516	X	-	27260156	T47D	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.0451545713560329	[602]	[638,728,708,639]	-1	hSpCas9	negative selection	8900545
18951203	18951226	X	+	27260156	SU8686	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.08365210743155949	[605]	[698,476,476,611]	-1	hSpCas9	negative selection	8957542
18954344	18954367	X	+	27260156	SU8686	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.3630015453140485	[1228]	[1346,1161,1851,2061]	6	hSpCas9	negative selection	8957543
18954400	18954423	X	-	27260156	SU8686	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.17196114170112686	[418]	[479,438,448,508]	3	hSpCas9	negative selection	8957544
18951098	18951121	X	+	27260156	SU8686	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.34251888873153036	[440]	[541,482,464,765]	6	hSpCas9	negative selection	9021794
18952519	18952542	X	-	27260156	SU8686	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.18857480251479064	[286]	[273,290,351,400]	3	hSpCas9	negative selection	9021795
18952493	18952516	X	-	27260156	SU8686	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.23915604414698644	[602]	[670,357,487,504]	-4	hSpCas9	negative selection	9021796
18951203	18951226	X	+	27260156	SKES1	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.3117428554523804	[605]	[607,500,314,533]	-6	hSpCas9	negative selection	9078793
18954344	18954367	X	+	27260156	SKES1	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.18604879295347954	[1228]	[1417,1553,1349,1278]	4	hSpCas9	negative selection	9078794
18954400	18954423	X	-	27260156	SKES1	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.05702006492262206	[418]	[443,636,394,300]	1	hSpCas9	negative selection	9078795
18951098	18951121	X	+	27260156	SKES1	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	0.07064608740927339	[440]	[524,475,459,399]	1	hSpCas9	negative selection	9143045
18952519	18952542	X	-	27260156	SKES1	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	0.025228499971800544	[286]	[308,298,318,243]	0	hSpCas9	negative selection	9143046
18952493	18952516	X	-	27260156	SKES1	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.12010279787310069	[602]	[498,726,476,522]	-3	hSpCas9	negative selection	9143047
18951203	18951226	X	+	27260156	TOV112D	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.29151496374033437	[605]	[548,575,387,493]	-5	hSpCas9	negative selection	9200044
18954344	18954367	X	+	27260156	TOV112D	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.03415692558413075	[1228]	[1474,1576,1131,959]	0	hSpCas9	negative selection	9200045
18954400	18954423	X	-	27260156	TOV112D	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	0.22569754741372167	[418]	[405,766,398,451]	4	hSpCas9	negative selection	9200046
18951098	18951121	X	+	27260156	TOV112D	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	-0.31908369326204616	[440]	[350,505,178,414]	-6	hSpCas9	negative selection	9264296
18952519	18952542	X	-	27260156	TOV112D	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.10230081895575505	[286]	[330,302,123,324]	-2	hSpCas9	negative selection	9264297
18952493	18952516	X	-	27260156	TOV112D	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.26619229573903613	[602]	[526,549,451,492]	-5	hSpCas9	negative selection	9264298
18951203	18951226	X	+	27260156	TC71	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	-0.25589960530598954	[605]	[621,556,505,486]	-6	hSpCas9	negative selection	9321295
18954344	18954367	X	+	27260156	TC71	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.03213321548487036	[1228]	[1253,1339,1207,1608]	0	hSpCas9	negative selection	9321296
18954400	18954423	X	-	27260156	TC71	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	-0.11343941671210098	[418]	[458,431,371,396]	-3	hSpCas9	negative selection	9321297
18951098	18951121	X	+	27260156	TC71	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	-0.1312130217914833	[440]	[424,460,432,405]	-3	hSpCas9	negative selection	9385547
18952519	18952542	X	-	27260156	TC71	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.17183015722680184	[286]	[282,312,261,231]	-4	hSpCas9	negative selection	9385548
18952493	18952516	X	-	27260156	TC71	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.12521461460372318	[602]	[515,600,580,679]	-3	hSpCas9	negative selection	9385549
18951203	18951226	X	+	27260156	TC32	viability	CGGTGTTGTACTTGGCGTGCAGG	PHKA2	ENSG00000044446	0.07563387411947592	[605]	[529,505,796,609]	1	hSpCas9	negative selection	9442546
18954344	18954367	X	+	27260156	TC32	viability	GTAGATGTTATCCCGCACCCAGG	PHKA2	ENSG00000044446	0.06712472974599848	[1228]	[1121,1035,1378,1340]	1	hSpCas9	negative selection	9442547
18954400	18954423	X	-	27260156	TC32	viability	TCTCTAATAGAATCCCGTCACGG	PHKA2	ENSG00000044446	-0.4425256037140892	[418]	[226,239,355,360]	-7	hSpCas9	negative selection	9442548
18951098	18951121	X	+	27260156	TC32	viability	GCTCACCTGAGGCGGTCATCTGG	PHKA2	ENSG00000044446	-0.0501244773154461	[440]	[424,211,525,511]	-1	hSpCas9	negative selection	9506798
18952519	18952542	X	-	27260156	TC32	viability	AACGTGGTGAAGCTGATGCGAGG	PHKA2	ENSG00000044446	-0.13728536064756358	[286]	[231,117,330,357]	-2	hSpCas9	negative selection	9506799
18952493	18952516	X	-	27260156	TC32	viability	TCTCCAGTGCATGATGAGACAGG	PHKA2	ENSG00000044446	-0.3423192022334423	[602]	[389,274,615,591]	-6	hSpCas9	negative selection	9506800
18941575	18941598	X	+	27869803	HPAFII	viability after 27 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	-0.07371016301249089	[304]	[117,180,NaN]	0	hSpCas9	negative selection	9608391
18945077	18945100	X	-	27869803	HPAFII	viability after 27 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	0.8132278948763252	[203]	[164,207,NaN]	6	hSpCas9	negative selection	9608392
18951260	18951283	X	-	27869803	HPAFII	viability after 27 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.6609907745722705	[457]	[371,387,NaN]	5	hSpCas9	negative selection	9608393
18952535	18952558	X	-	27869803	HPAFII	viability after 27 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.9829808421138556	[417]	[303,542,NaN]	7	hSpCas9	negative selection	9608394
18954253	18954276	X	-	27869803	HPAFII	viability after 27 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	1.774784072002348	[146]	[174,338,NaN]	9	hSpCas9	negative selection	9608395
18983845	18983868	X	+	27869803	HPAFII	viability after 27 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.8166419914554488	[677]	[1025,295,NaN]	6	hSpCas9	negative selection	9608396
18941575	18941598	X	+	27869803	HPAFII	viability after 15 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	0.12984356326979202	[304]	[489,276,NaN]	1	hSpCas9	negative selection	9690840
18945077	18945100	X	-	27869803	HPAFII	viability after 15 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	-0.0866608909349097	[203]	[166,230,NaN]	-1	hSpCas9	negative selection	9690841
18951260	18951283	X	-	27869803	HPAFII	viability after 15 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.2646037425308605	[457]	[742,496,NaN]	3	hSpCas9	negative selection	9690842
18952535	18952558	X	-	27869803	HPAFII	viability after 15 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.4699986656168039	[417]	[538,673,NaN]	5	hSpCas9	negative selection	9690843
18954253	18954276	X	-	27869803	HPAFII	viability after 15 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	1.0983258698946234	[146]	[402,297,NaN]	9	hSpCas9	negative selection	9690844
18983845	18983868	X	+	27869803	HPAFII	viability after 15 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.5270651483050703	[677]	[1628,689,NaN]	6	hSpCas9	negative selection	9690845
18941575	18941598	X	+	27869803	ASPC1	viability after 36 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	-0.9855379145600451	[773]	[105,112,174]	-7	hSpCas9	negative selection	9773289
18945077	18945100	X	-	27869803	ASPC1	viability after 36 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	0.6140688824046858	[362]	[335,95,169]	6	hSpCas9	negative selection	9773290
18951260	18951283	X	-	27869803	ASPC1	viability after 36 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	-0.5044026173337693	[1230]	[192,400,298]	-5	hSpCas9	negative selection	9773291
18952535	18952558	X	-	27869803	ASPC1	viability after 36 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.3964255266764878	[1029]	[393,428,558]	4	hSpCas9	negative selection	9773292
18954253	18954276	X	-	27869803	ASPC1	viability after 36 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	-0.640414566649786	[710]	[167,131,172]	-6	hSpCas9	negative selection	9773293
18983845	18983868	X	+	27869803	ASPC1	viability after 36 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	-0.3678651207497272	[1637]	[453,564,333]	-4	hSpCas9	negative selection	9773294
18941575	18941598	X	+	27869803	PATU8988S	viability after 35 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	-0.0413303200673083	[612]	[201,277,NaN]	0	hSpCas9	negative selection	9855738
18945077	18945100	X	-	27869803	PATU8988S	viability after 35 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	0.7410754258958911	[357]	[237,243,NaN]	7	hSpCas9	negative selection	9855739
18951260	18951283	X	-	27869803	PATU8988S	viability after 35 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.03389107924138535	[1001]	[477,347,NaN]	0	hSpCas9	negative selection	9855740
18952535	18952558	X	-	27869803	PATU8988S	viability after 35 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.8136713601678053	[853]	[626,581,NaN]	8	hSpCas9	negative selection	9855741
18954253	18954276	X	-	27869803	PATU8988S	viability after 35 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	0.15860943154160972	[493]	[256,186,NaN]	1	hSpCas9	negative selection	9855742
18983845	18983868	X	+	27869803	PATU8988S	viability after 35 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	0.040730250535338186	[1531]	[713,554,NaN]	0	hSpCas9	negative selection	9855743
18941575	18941598	X	+	27869803	PATU8988S	viability after 31 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	-0.37804352141511827	[612]	[206,163,NaN]	-4	hSpCas9	negative selection	9938187
18945077	18945100	X	-	27869803	PATU8988S	viability after 31 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	0.575747461890302	[357]	[221,200,NaN]	7	hSpCas9	negative selection	9938188
18951260	18951283	X	-	27869803	PATU8988S	viability after 31 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.036298738592794644	[1001]	[414,402,NaN]	0	hSpCas9	negative selection	9938189
18952535	18952558	X	-	27869803	PATU8988S	viability after 31 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.4149090075183758	[853]	[431,481,NaN]	5	hSpCas9	negative selection	9938190
18954253	18954276	X	-	27869803	PATU8988S	viability after 31 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	0.48037624840025983	[493]	[309,229,NaN]	6	hSpCas9	negative selection	9938191
18983845	18983868	X	+	27869803	PATU8988S	viability after 31 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	-0.0868487875017756	[1531]	[506,661,NaN]	-1	hSpCas9	negative selection	9938192
18941575	18941598	X	+	27869803	HPAFII	viability after 35 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	0.11527699746772957	[304]	[194,135,NaN]	0	hSpCas9	negative selection	10020636
18945077	18945100	X	-	27869803	HPAFII	viability after 35 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	0.7099689238780428	[203]	[151,187,NaN]	5	hSpCas9	negative selection	10020637
18951260	18951283	X	-	27869803	HPAFII	viability after 35 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	1.0272785334236678	[457]	[322,640,NaN]	7	hSpCas9	negative selection	10020638
18952535	18952558	X	-	27869803	HPAFII	viability after 35 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.8435342133960876	[417]	[176,607,NaN]	5	hSpCas9	negative selection	10020639
18954253	18954276	X	-	27869803	HPAFII	viability after 35 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	2.487700266110148	[146]	[153,713,NaN]	9	hSpCas9	negative selection	10020640
18983845	18983868	X	+	27869803	HPAFII	viability after 35 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	1.2087136756136394	[677]	[1091,456,NaN]	7	hSpCas9	negative selection	10020641
18941575	18941598	X	+	27869803	HPAFII	viability after 31 days	ACATCTTCCACTGCAAAGGCCGG	PHKA2	ENSG00000044446	-0.042579665621399865	[304]	[136,197,NaN]	0	hSpCas9	negative selection	10103085
18945077	18945100	X	-	27869803	HPAFII	viability after 31 days	AAGCTCCGTAGGAATGGCCAAGG	PHKA2	ENSG00000044446	0.40656646987086814	[203]	[123,181,NaN]	3	hSpCas9	negative selection	10103086
18951260	18951283	X	-	27869803	HPAFII	viability after 31 days	TCTCCCTCAGGTGGCCAAAGTGG	PHKA2	ENSG00000044446	0.9762442456502569	[457]	[397,622,NaN]	7	hSpCas9	negative selection	10103087
18952535	18952558	X	-	27869803	HPAFII	viability after 31 days	TGCTTTATCTCCACAGAACGTGG	PHKA2	ENSG00000044446	0.9265884570209172	[417]	[264,642,NaN]	7	hSpCas9	negative selection	10103088
18954253	18954276	X	-	27869803	HPAFII	viability after 31 days	CAAGGCCTACGAGCTGGAGCAGG	PHKA2	ENSG00000044446	2.4606558511658085	[146]	[188,742,NaN]	9	hSpCas9	negative selection	10103089
18983845	18983868	X	+	27869803	HPAFII	viability after 31 days	CCCTCCTTACCTGGTAACACAGG	PHKA2	ENSG00000044446	1.1683839282336248	[677]	[1183,496,NaN]	8	hSpCas9	negative selection	10103090
18951152	18951175	X	-	28162770	P31FUJ	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	0.2875073379645242	[250]	[359]	3	hSpCas9	negative selection	10210638
18901500	18901523	X	-	28162770	P31FUJ	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	0.8515547259681393	[464]	[985]	8	hSpCas9	negative selection	10210639
18951140	18951163	X	+	28162770	P31FUJ	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	0.1366831430500579	[369]	[477]	1	hSpCas9	negative selection	10210640
18936123	18936146	X	-	28162770	P31FUJ	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	-0.3251662225630382	[128]	[120]	-3	hSpCas9	negative selection	10210641
18936107	18936130	X	-	28162770	P31FUJ	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.7180501462565332	[208]	[403]	7	hSpCas9	negative selection	10210642
18924453	18924476	X	-	28162770	P31FUJ	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	0.6602825916691093	[62]	[116]	7	hSpCas9	negative selection	10210643
18918738	18918761	X	+	28162770	P31FUJ	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	-0.27127635222901425	[37]	[36]	-3	hSpCas9	negative selection	10210644
18908894	18908917	X	-	28162770	P31FUJ	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	1.0897206936316415	[484]	[1212]	9	hSpCas9	negative selection	10210645
18907055	18907078	X	-	28162770	P31FUJ	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.9883701787598135	[337]	[787]	9	hSpCas9	negative selection	10210646
18907018	18907041	X	+	28162770	P31FUJ	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	0.5277107242046766	[473]	[802]	6	hSpCas9	negative selection	10210647
18951152	18951175	X	-	28162770	TF1	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	NaN	[NaN]	[104]	1	hSpCas9	negative selection	10380004
18901500	18901523	X	-	28162770	TF1	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	NaN	[NaN]	[754]	1	hSpCas9	negative selection	10380005
18951140	18951163	X	+	28162770	TF1	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	NaN	[NaN]	[303]	1	hSpCas9	negative selection	10380006
18936123	18936146	X	-	28162770	TF1	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10380007
18936107	18936130	X	-	28162770	TF1	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	NaN	[NaN]	[447]	1	hSpCas9	negative selection	10380008
18924453	18924476	X	-	28162770	TF1	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	NaN	[NaN]	[190]	1	hSpCas9	negative selection	10380009
18918738	18918761	X	+	28162770	TF1	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10380010
18908894	18908917	X	-	28162770	TF1	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	NaN	[NaN]	[792]	1	hSpCas9	negative selection	10380011
18907055	18907078	X	-	28162770	TF1	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	NaN	[NaN]	[394]	1	hSpCas9	negative selection	10380012
18907018	18907041	X	+	28162770	TF1	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	NaN	[NaN]	[711]	1	hSpCas9	negative selection	10380013
18951152	18951175	X	-	28162770	SKM1	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	0.7028398102615798	[48]	[140]	6	hSpCas9	negative selection	10549370
18901500	18901523	X	-	28162770	SKM1	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	0.38311273188260686	[107]	[248]	4	hSpCas9	negative selection	10549371
18951140	18951163	X	+	28162770	SKM1	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	-0.7934325458252347	[99]	[101]	-5	hSpCas9	negative selection	10549372
18936123	18936146	X	-	28162770	SKM1	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	-0.09851933321942152	[42]	[70]	-1	hSpCas9	negative selection	10549373
18936107	18936130	X	-	28162770	SKM1	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.4528581432085781	[80]	[195]	4	hSpCas9	negative selection	10549374
18924453	18924476	X	-	28162770	SKM1	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	-0.5138794026596734	[20]	[25]	-4	hSpCas9	negative selection	10549375
18918738	18918761	X	+	28162770	SKM1	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	0.1290887014970481	[14]	[28]	1	hSpCas9	negative selection	10549376
18908894	18908917	X	-	28162770	SKM1	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.413811239076764	[106]	[251]	4	hSpCas9	negative selection	10549377
18907055	18907078	X	-	28162770	SKM1	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.09447494641571108	[79]	[150]	0	hSpCas9	negative selection	10549378
18907018	18907041	X	+	28162770	SKM1	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	-0.4128890327002669	[121]	[161]	-3	hSpCas9	negative selection	10549379
18951152	18951175	X	-	28162770	SKM1	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	0.7028398102615798	[48]	[140]	6	hSpCas9	negative selection	10718736
18901500	18901523	X	-	28162770	SKM1	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	0.38311273188260686	[107]	[248]	4	hSpCas9	negative selection	10718737
18951140	18951163	X	+	28162770	SKM1	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	-0.7934325458252347	[99]	[101]	-5	hSpCas9	negative selection	10718738
18936123	18936146	X	-	28162770	SKM1	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	-0.09851933321942152	[42]	[70]	-1	hSpCas9	negative selection	10718739
18936107	18936130	X	-	28162770	SKM1	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.4528581432085781	[80]	[195]	4	hSpCas9	negative selection	10718740
18924453	18924476	X	-	28162770	SKM1	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	-0.5138794026596734	[20]	[25]	-4	hSpCas9	negative selection	10718741
18918738	18918761	X	+	28162770	SKM1	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	0.1290887014970481	[14]	[28]	1	hSpCas9	negative selection	10718742
18908894	18908917	X	-	28162770	SKM1	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.413811239076764	[106]	[251]	4	hSpCas9	negative selection	10718743
18907055	18907078	X	-	28162770	SKM1	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.09447494641571108	[79]	[150]	0	hSpCas9	negative selection	10718744
18907018	18907041	X	+	28162770	SKM1	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	-0.4128890327002669	[121]	[161]	-3	hSpCas9	negative selection	10718745
18951152	18951175	X	-	28162770	PL21	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	-0.8370590034649292	[274]	[66]	-5	hSpCas9	negative selection	10888102
18901500	18901523	X	-	28162770	PL21	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	-0.9175554281804346	[433]	[99]	-6	hSpCas9	negative selection	10888103
18951140	18951163	X	+	28162770	PL21	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	0.4492592737444866	[381]	[226]	4	hSpCas9	negative selection	10888104
18936123	18936146	X	-	28162770	PL21	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	1.1543359248761953	[127]	[123]	8	hSpCas9	negative selection	10888105
18936107	18936130	X	-	28162770	PL21	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.15384596221538516	[284]	[137]	1	hSpCas9	negative selection	10888106
18924453	18924476	X	-	28162770	PL21	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	-1.094043489915138	[102]	[20]	-6	hSpCas9	negative selection	10888107
18918738	18918761	X	+	28162770	PL21	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	-0.38482288623183614	[59]	[19]	-3	hSpCas9	negative selection	10888108
18908894	18908917	X	-	28162770	PL21	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.16892088387859983	[326]	[159]	1	hSpCas9	negative selection	10888109
18907055	18907078	X	-	28162770	PL21	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.981834150676115	[234]	[201]	7	hSpCas9	negative selection	10888110
18907018	18907041	X	+	28162770	PL21	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	0.7218099622593906	[364]	[261]	6	hSpCas9	negative selection	10888111
18951152	18951175	X	-	28162770	P31FUJ	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	0.2875073379645242	[250]	[359]	3	hSpCas9	negative selection	11057468
18901500	18901523	X	-	28162770	P31FUJ	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	0.8515547259681393	[464]	[985]	8	hSpCas9	negative selection	11057469
18951140	18951163	X	+	28162770	P31FUJ	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	0.1366831430500579	[369]	[477]	1	hSpCas9	negative selection	11057470
18936123	18936146	X	-	28162770	P31FUJ	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	-0.3251662225630382	[128]	[120]	-3	hSpCas9	negative selection	11057471
18936107	18936130	X	-	28162770	P31FUJ	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.7180501462565332	[208]	[403]	7	hSpCas9	negative selection	11057472
18924453	18924476	X	-	28162770	P31FUJ	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	0.6602825916691093	[62]	[116]	7	hSpCas9	negative selection	11057473
18918738	18918761	X	+	28162770	P31FUJ	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	-0.27127635222901425	[37]	[36]	-3	hSpCas9	negative selection	11057474
18908894	18908917	X	-	28162770	P31FUJ	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	1.0897206936316415	[484]	[1212]	9	hSpCas9	negative selection	11057475
18907055	18907078	X	-	28162770	P31FUJ	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.9883701787598135	[337]	[787]	9	hSpCas9	negative selection	11057476
18907018	18907041	X	+	28162770	P31FUJ	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	0.5277107242046766	[473]	[802]	6	hSpCas9	negative selection	11057477
18951152	18951175	X	-	28162770	OCIAML5	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	1.1316316168069027	[88]	[351]	8	hSpCas9	negative selection	11226834
18901500	18901523	X	-	28162770	OCIAML5	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	0.7849426776267547	[244]	[761]	7	hSpCas9	negative selection	11226835
18951140	18951163	X	+	28162770	OCIAML5	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	0.08971881519070724	[176]	[339]	0	hSpCas9	negative selection	11226836
18936123	18936146	X	-	28162770	OCIAML5	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	0.5985948381455682	[74]	[204]	5	hSpCas9	negative selection	11226837
18936107	18936130	X	-	28162770	OCIAML5	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.6907704541844826	[138]	[404]	6	hSpCas9	negative selection	11226838
18924453	18924476	X	-	28162770	OCIAML5	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	0.4142134944734509	[73]	[177]	3	hSpCas9	negative selection	11226839
18918738	18918761	X	+	28162770	OCIAML5	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	0.546482805626278	[32]	[86]	5	hSpCas9	negative selection	11226840
18908894	18908917	X	-	28162770	OCIAML5	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.4925475742957588	[264]	[672]	4	hSpCas9	negative selection	11226841
18907055	18907078	X	-	28162770	OCIAML5	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	1.0257615591420588	[116]	[429]	8	hSpCas9	negative selection	11226842
18907018	18907041	X	+	28162770	OCIAML5	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	-0.285025978140103	[296]	[439]	-2	hSpCas9	negative selection	11226843
18951152	18951175	X	-	28162770	EOL1	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	-0.45792186525187856	[437]	[167]	-3	hSpCas9	negative selection	11396200
18901500	18901523	X	-	28162770	EOL1	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	0.908814845305938	[460]	[455]	7	hSpCas9	negative selection	11396201
18951140	18951163	X	+	28162770	EOL1	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	-0.15637222381303273	[714]	[337]	-1	hSpCas9	negative selection	11396202
18936123	18936146	X	-	28162770	EOL1	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	0.9465740779005336	[259]	[263]	7	hSpCas9	negative selection	11396203
18936107	18936130	X	-	28162770	EOL1	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.8250120980196202	[539]	[503]	7	hSpCas9	negative selection	11396204
18924453	18924476	X	-	28162770	EOL1	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	1.4310836253348744	[125]	[178]	9	hSpCas9	negative selection	11396205
18918738	18918761	X	+	28162770	EOL1	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	1.7234078994626834	[72]	[126]	9	hSpCas9	negative selection	11396206
18908894	18908917	X	-	28162770	EOL1	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	1.0136313151529597	[470]	[500]	8	hSpCas9	negative selection	11396207
18907055	18907078	X	-	28162770	EOL1	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.8860736237558989	[341]	[332]	7	hSpCas9	negative selection	11396208
18907018	18907041	X	+	28162770	EOL1	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	-0.3092981667357121	[547]	[232]	-2	hSpCas9	negative selection	11396209
18951152	18951175	X	-	28162770	MOLM13	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	0.32508878114555484	[381]	[345]	2	hSpCas9	negative selection	11565566
18901500	18901523	X	-	28162770	MOLM13	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	0.47069891513140294	[512]	[513]	3	hSpCas9	negative selection	11565567
18951140	18951163	X	+	28162770	MOLM13	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	0.46031616183977797	[572]	[569]	3	hSpCas9	negative selection	11565568
18936123	18936146	X	-	28162770	MOLM13	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	0.6303198464399669	[192]	[215]	5	hSpCas9	negative selection	11565569
18936107	18936130	X	-	28162770	MOLM13	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.223686650441157	[410]	[346]	1	hSpCas9	negative selection	11565570
18924453	18924476	X	-	28162770	MOLM13	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	1.0804641134735948	[137]	[210]	8	hSpCas9	negative selection	11565571
18918738	18918761	X	+	28162770	MOLM13	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	-5.414753667817263	[58]	[0]	-9	hSpCas9	negative selection	11565572
18908894	18908917	X	-	28162770	MOLM13	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.09819486772648911	[521]	[403]	0	hSpCas9	negative selection	11565573
18907055	18907078	X	-	28162770	MOLM13	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	-0.3909958411531074	[398]	[219]	-2	hSpCas9	negative selection	11565574
18907018	18907041	X	+	28162770	MOLM13	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	0.21567025846862098	[504]	[423]	1	hSpCas9	negative selection	11565575
18951152	18951175	X	-	28162770	HEL	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	0.8574204116731868	[267]	[310]	7	hSpCas9	negative selection	11734932
18901500	18901523	X	-	28162770	HEL	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	0.772231071633079	[393]	[430]	6	hSpCas9	negative selection	11734933
18951140	18951163	X	+	28162770	HEL	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	0.4028465059790063	[469]	[397]	3	hSpCas9	negative selection	11734934
18936123	18936146	X	-	28162770	HEL	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	0.7152513317847249	[193]	[203]	6	hSpCas9	negative selection	11734935
18936107	18936130	X	-	28162770	HEL	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.3198195347099445	[363]	[290]	2	hSpCas9	negative selection	11734936
18924453	18924476	X	-	28162770	HEL	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	1.2737709814174982	[112]	[174]	9	hSpCas9	negative selection	11734937
18918738	18918761	X	+	28162770	HEL	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	1.6707532081699537	[50]	[103]	9	hSpCas9	negative selection	11734938
18908894	18908917	X	-	28162770	HEL	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.5169270786918421	[466]	[427]	4	hSpCas9	negative selection	11734939
18907055	18907078	X	-	28162770	HEL	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.7973866467009705	[326]	[363]	7	hSpCas9	negative selection	11734940
18907018	18907041	X	+	28162770	HEL	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	0.2514174016953208	[361]	[275]	2	hSpCas9	negative selection	11734941
18951152	18951175	X	-	28162770	MV411	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	1.1102694985006671	[214]	[390]	8	hSpCas9	negative selection	11904298
18901500	18901523	X	-	28162770	MV411	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	-0.016327518546448427	[394]	[328]	0	hSpCas9	negative selection	11904299
18951140	18951163	X	+	28162770	MV411	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	0.49053310956323815	[424]	[502]	4	hSpCas9	negative selection	11904300
18936123	18936146	X	-	28162770	MV411	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	0.6848428630900736	[143]	[194]	6	hSpCas9	negative selection	11904301
18936107	18936130	X	-	28162770	MV411	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.37825676122749674	[294]	[322]	3	hSpCas9	negative selection	11904302
18924453	18924476	X	-	28162770	MV411	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	0.7682697140842158	[91]	[131]	7	hSpCas9	negative selection	11904303
18918738	18918761	X	+	28162770	MV411	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	0.34054695517425704	[44]	[47]	3	hSpCas9	negative selection	11904304
18908894	18908917	X	-	28162770	MV411	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.3978543933358738	[363]	[403]	3	hSpCas9	negative selection	11904305
18907055	18907078	X	-	28162770	MV411	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.7791018253438824	[192]	[278]	7	hSpCas9	negative selection	11904306
18907018	18907041	X	+	28162770	MV411	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	1.1005143747020785	[314]	[568]	8	hSpCas9	negative selection	11904307
18951152	18951175	X	-	28162770	MONOMAC1	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	0.1055259229608776	[149]	[184]	1	hSpCas9	negative selection	12073664
18901500	18901523	X	-	28162770	MONOMAC1	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	-0.09750117350863918	[223]	[239]	-1	hSpCas9	negative selection	12073665
18951140	18951163	X	+	28162770	MONOMAC1	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	-0.023922158178443453	[250]	[282]	0	hSpCas9	negative selection	12073666
18936123	18936146	X	-	28162770	MONOMAC1	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	0.025355574276894277	[71]	[83]	0	hSpCas9	negative selection	12073667
18936107	18936130	X	-	28162770	MONOMAC1	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.09401193494383664	[169]	[207]	1	hSpCas9	negative selection	12073668
18924453	18924476	X	-	28162770	MONOMAC1	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	0.265306366997647	[44]	[61]	2	hSpCas9	negative selection	12073669
18918738	18918761	X	+	28162770	MONOMAC1	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	0.4717572444650733	[38]	[61]	4	hSpCas9	negative selection	12073670
18908894	18908917	X	-	28162770	MONOMAC1	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.7676300798281657	[247]	[483]	7	hSpCas9	negative selection	12073671
18907055	18907078	X	-	28162770	MONOMAC1	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.5600363205552275	[170]	[288]	5	hSpCas9	negative selection	12073672
18907018	18907041	X	+	28162770	MONOMAC1	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	-0.24347242004983827	[220]	[213]	-2	hSpCas9	negative selection	12073673
18951152	18951175	X	-	28162770	OCIAML2	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	0.33168950691814447	[40]	[285]	3	hSpCas9	negative selection	12243030
18901500	18901523	X	-	28162770	OCIAML2	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	0.32583678067270694	[75]	[527]	3	hSpCas9	negative selection	12243031
18951140	18951163	X	+	28162770	OCIAML2	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	0.45763442115892417	[66]	[509]	4	hSpCas9	negative selection	12243032
18936123	18936146	X	-	28162770	OCIAML2	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	0.7042958572585176	[31]	[288]	7	hSpCas9	negative selection	12243033
18936107	18936130	X	-	28162770	OCIAML2	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.5156952378607622	[52]	[419]	5	hSpCas9	negative selection	12243034
18924453	18924476	X	-	28162770	OCIAML2	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	0.901924342715169	[13]	[144]	8	hSpCas9	negative selection	12243035
18918738	18918761	X	+	28162770	OCIAML2	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	1.031870515287022	[2]	[33]	8	hSpCas9	negative selection	12243036
18908894	18908917	X	-	28162770	OCIAML2	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.8357574187494229	[55]	[553]	7	hSpCas9	negative selection	12243037
18907055	18907078	X	-	28162770	OCIAML2	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.5728718133944256	[48]	[403]	5	hSpCas9	negative selection	12243038
18907018	18907041	X	+	28162770	OCIAML2	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	0.10319211787379456	[64]	[386]	1	hSpCas9	negative selection	12243039
18951152	18951175	X	-	28162770	OCIAML3	viability	CCAGTGGGGCCACCTCCAGGTGG	PHKA2	ENSG00000044446	0.3276044609911209	[51]	[196]	3	hSpCas9	negative selection	12412396
18901500	18901523	X	-	28162770	OCIAML3	viability	GGAGTGGCATTAACAGACTGAGG	PHKA2	ENSG00000044446	0.4167721984290794	[99]	[402]	4	hSpCas9	negative selection	12412397
18951140	18951163	X	+	28162770	OCIAML3	viability	GAGAGGTGGCATCCACCTGGAGG	PHKA2	ENSG00000044446	0.655606249747309	[89]	[427]	6	hSpCas9	negative selection	12412398
18936123	18936146	X	-	28162770	OCIAML3	viability	AGAATACCGAGAGGCCCTGGAGG	PHKA2	ENSG00000044446	1.7823682385855757	[25]	[269]	9	hSpCas9	negative selection	12412399
18936107	18936130	X	-	28162770	OCIAML3	viability	CTGGAGGGAATACTCATCAGAGG	PHKA2	ENSG00000044446	0.21017303393829734	[64]	[226]	2	hSpCas9	negative selection	12412400
18924453	18924476	X	-	28162770	OCIAML3	viability	GGAGATGCTAAGGATCGAGCTGG	PHKA2	ENSG00000044446	0.47874870211115095	[28]	[121]	4	hSpCas9	negative selection	12412401
18918738	18918761	X	+	28162770	OCIAML3	viability	GGATAGCACTGAAGACATGGCGG	PHKA2	ENSG00000044446	-0.2093437900888382	[17]	[46]	-2	hSpCas9	negative selection	12412402
18908894	18908917	X	-	28162770	OCIAML3	viability	CAGTGGCCCAGAGATGACCATGG	PHKA2	ENSG00000044446	0.8454140175816398	[98]	[536]	7	hSpCas9	negative selection	12412403
18907055	18907078	X	-	28162770	OCIAML3	viability	GCACCAGAAGCAGCTCACCGTGG	PHKA2	ENSG00000044446	0.39748085982031933	[84]	[337]	3	hSpCas9	negative selection	12412404
18907018	18907041	X	+	28162770	OCIAML3	viability	GCAGAGATGATCTTCTCCCGGGG	PHKA2	ENSG00000044446	0.7158476222626243	[95]	[475]	6	hSpCas9	negative selection	12412405