Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 65018
• Symbol: PINK1
• Description: PTEN induced kinase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PINK1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
20633856	20633879	1	-	26472758	Jiyoye	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	-0.7333058420439569	[96]	[43]	-5	hSpCas9	negative selection	120888
20638043	20638066	1	+	26472758	Jiyoye	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	-0.0623099017953469	[89]	[64]	0	hSpCas9	negative selection	120889
20637849	20637872	1	+	26472758	Jiyoye	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-0.1288775187343365	[57]	[39]	-1	hSpCas9	negative selection	120890
20639948	20639971	1	+	26472758	Jiyoye	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	0.017763689902524138	[92]	[70]	0	hSpCas9	negative selection	120891
20633578	20633601	1	-	26472758	Jiyoye	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	-0.4571695191365603	[141]	[77]	-3	hSpCas9	negative selection	120892
20637982	20638005	1	+	26472758	Jiyoye	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	0.3400611856473361	[21]	[20]	2	hSpCas9	negative selection	120893
20637998	20638021	1	+	26472758	Jiyoye	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	0.4467037456925107	[35]	[36]	3	hSpCas9	negative selection	120894
20633856	20633879	1	-	26472758	KBM7	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	-0.33573934344071343	[499,229]	[121,139]	-3	hSpCas9	negative selection	312006
20638043	20638066	1	+	26472758	KBM7	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	-1.0084928130992936	[239,249]	[82,34]	-7	hSpCas9	negative selection	312007
20637849	20637872	1	+	26472758	KBM7	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-0.7496262957704423	[191,160]	[83,17]	-6	hSpCas9	negative selection	312008
20639948	20639971	1	+	26472758	KBM7	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	-0.3297508221080638	[760,461]	[154,285]	-3	hSpCas9	negative selection	312009
20633578	20633601	1	-	26472758	KBM7	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.5654692905446119	[708,607]	[393,512]	6	hSpCas9	negative selection	312010
20637982	20638005	1	+	26472758	KBM7	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	1.3763646353161845	[55,69]	[46,105]	9	hSpCas9	negative selection	312011
20637998	20638021	1	+	26472758	KBM7	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	-0.47230935363043947	[237,238]	[104,59]	-4	hSpCas9	negative selection	312012
20633856	20633879	1	-	26472758	Raji	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	0.15417774685254063	[181]	[46]	1	hSpCas9	negative selection	503124
20638043	20638066	1	+	26472758	Raji	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	-0.04461955807145046	[199]	[44]	0	hSpCas9	negative selection	503125
20637849	20637872	1	+	26472758	Raji	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	1.2892218583594126	[66]	[37]	9	hSpCas9	negative selection	503126
20639948	20639971	1	+	26472758	Raji	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	0.33076174085560306	[208]	[60]	3	hSpCas9	negative selection	503127
20633578	20633601	1	-	26472758	Raji	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.4650335524949234	[358]	[114]	4	hSpCas9	negative selection	503128
20637982	20638005	1	+	26472758	Raji	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	1.1654864899371677	[72]	[37]	8	hSpCas9	negative selection	503129
20637998	20638021	1	+	26472758	Raji	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	0.3277736037988994	[102]	[29]	3	hSpCas9	negative selection	503130
20633856	20633879	1	-	26472758	K562	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	-0.611505094660132	[218]	[120]	-4	hSpCas9	negative selection	694242
20638043	20638066	1	+	26472758	K562	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	0.8794219108871986	[254]	[395]	7	hSpCas9	negative selection	694243
20637849	20637872	1	+	26472758	K562	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-0.8616229097438775	[126]	[58]	-5	hSpCas9	negative selection	694244
20639948	20639971	1	+	26472758	K562	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	-0.6238505739147644	[386]	[211]	-4	hSpCas9	negative selection	694245
20633578	20633601	1	-	26472758	K562	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.661941490334885	[434]	[580]	5	hSpCas9	negative selection	694246
20637982	20638005	1	+	26472758	K562	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	-1.8365012677171206	[109]	[25]	-7	hSpCas9	negative selection	694247
20637998	20638021	1	+	26472758	K562	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	-0.24951959935931223	[237]	[168]	-2	hSpCas9	negative selection	694248
20633830	20633853	1	-	26627737	DLD1	viability	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-0.44666466570784824	[417]	[122,47,111]	-4	hSpCas9	negative selection	768879
20638098	20638121	1	-	26627737	DLD1	viability	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	0.4873108620075367	[768]	[469,274,272]	5	hSpCas9	negative selection	768880
20633830	20633853	1	-	26627737	GBM cells	viability after 5 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-0.32009590705611035	[141]	[89,31]	-5	hSpCas9	negative selection	851194
20638098	20638121	1	-	26627737	GBM cells	viability after 5 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	0.5759519605052209	[348]	[318,238]	8	hSpCas9	negative selection	851195
20633830	20633853	1	-	26627737	GBM cells	viability after 13 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-0.6962259421286973	[141]	[46,47]	-7	hSpCas9	negative selection	933509
20638098	20638121	1	-	26627737	GBM cells	viability after 13 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	0.6831218747987698	[348]	[308,299]	8	hSpCas9	negative selection	933510
20633830	20633853	1	-	26627737	GBM cells	viability after 21 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	0.3290763588629075	[141]	[98,94]	3	hSpCas9	negative selection	1015824
20638098	20638121	1	-	26627737	GBM cells	viability after 21 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	0.5473551238871398	[348]	[274,278]	5	hSpCas9	negative selection	1015825
20633830	20633853	1	-	26627737	RPE1	viability after 9 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	0.66284240383462	[522]	[277,234]	4	hSpCas9	negative selection	1098139
20638098	20638121	1	-	26627737	RPE1	viability after 9 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	-1.0529983166425205	[2024]	[236,393]	-6	hSpCas9	negative selection	1098140
20633830	20633853	1	-	26627737	RPE1	viability after 12 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	0.6755568186627889	[522]	[238,208]	4	hSpCas9	negative selection	1180454
20638098	20638121	1	-	26627737	RPE1	viability after 12 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	-0.5861556358273388	[2024]	[324,401]	-4	hSpCas9	negative selection	1180455
20633830	20633853	1	-	26627737	RPE1	viability after 15 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	0.7433947456082944	[522]	[293,202]	4	hSpCas9	negative selection	1262769
20638098	20638121	1	-	26627737	RPE1	viability after 15 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	-1.4091869351536888	[2024]	[120,306]	-7	hSpCas9	negative selection	1262770
20633830	20633853	1	-	26627737	RPE1	viability after 18 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	1.0090852597717634	[522]	[387,172]	6	hSpCas9	negative selection	1345084
20638098	20638121	1	-	26627737	RPE1	viability after 18 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	-1.00077996888855	[2024]	[304,238]	-6	hSpCas9	negative selection	1345085
20633830	20633853	1	-	26627737	HeLa	viability after 8 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-1.342058289508915	[496]	[85,142,30]	-8	hSpCas9	negative selection	1427399
20638098	20638121	1	-	26627737	HeLa	viability after 8 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	-0.46977775580233627	[630]	[152,176,250]	-4	hSpCas9	negative selection	1427400
20633830	20633853	1	-	26627737	HeLa	viability after 12 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-0.6327200205862414	[496]	[289,37,83]	-5	hSpCas9	negative selection	1509714
20638098	20638121	1	-	26627737	HeLa	viability after 12 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	0.3744248811216817	[630]	[373,216,436]	3	hSpCas9	negative selection	1509715
20633830	20633853	1	-	26627737	HeLa	viability after 15 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-2.2788494576998675	[496]	[49,44,28]	-9	hSpCas9	negative selection	1592029
20638098	20638121	1	-	26627737	HeLa	viability after 15 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	0.09957106221628342	[630]	[50,400,384]	0	hSpCas9	negative selection	1592030
20633830	20633853	1	-	26627737	HeLa	viability after 18 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-2.2291456627427344	[496]	[34,38,28]	-9	hSpCas9	negative selection	1674344
20638098	20638121	1	-	26627737	HeLa	viability after 18 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	0.07442729746629939	[630]	[28,326,384]	0	hSpCas9	negative selection	1674345
20633830	20633853	1	-	26627737	HCT116	viability after 6 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-0.4307525243567456	[257]	[22,33]	-2	hSpCas9	negative selection	1756659
20638098	20638121	1	-	26627737	HCT116	viability after 6 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	-1.1361808249298138	[863]	[84,48]	-6	hSpCas9	negative selection	1756660
20633830	20633853	1	-	26627737	HCT116	viability after 8 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-0.42274823752944557	[201]	[52,147,47]	-5	hSpCas9	negative selection	1838974
20638098	20638121	1	-	26627737	HCT116	viability after 8 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	-0.4074431015811524	[398]	[235,133,128]	-5	hSpCas9	negative selection	1838975
20633830	20633853	1	-	26627737	HCT116	viability after 9 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-0.662845836696756	[257]	[71,20]	-5	hSpCas9	negative selection	1921289
20638098	20638121	1	-	26627737	HCT116	viability after 9 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	1.2745031047552204	[863]	[413,671]	8	hSpCas9	negative selection	1921290
20633830	20633853	1	-	26627737	HCT116	viability after 12 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-0.780883577694986	[201]	[10,151,28]	-7	hSpCas9	negative selection	2003604
20638098	20638121	1	-	26627737	HCT116	viability after 12 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	-0.09193360025859432	[398]	[262,138,180]	-1	hSpCas9	negative selection	2003605
20633830	20633853	1	-	26627737	HCT116	viability after 15 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-0.5209626988643469	[201]	[61,159,18]	-5	hSpCas9	negative selection	2085919
20638098	20638121	1	-	26627737	HCT116	viability after 15 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	0.09160587800956971	[398]	[298,181,257]	0	hSpCas9	negative selection	2085920
20633830	20633853	1	-	26627737	HCT116	viability after 18 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-0.4816672913024841	[201]	[23,129,50]	-4	hSpCas9	negative selection	2168234
20638098	20638121	1	-	26627737	HCT116	viability after 18 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	-0.34296728177357094	[398]	[143,148,163]	-3	hSpCas9	negative selection	2168235
20633542	20633565	1	+	24336569	HL60	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	1.3886779980904018	[426]	[2365]	8	hSpCas9	negative selection	2284196
20633547	20633570	1	-	24336569	HL60	viability	CAGCGCCTGTCGCACCGCCATGG	PINK1	ENSG00000158828	0.41397247146389493	[553]	[1561]	4	hSpCas9	negative selection	2284197
20633555	20633578	1	+	24336569	HL60	viability	GTGCGACAGGCGCTGGGCCGCGG	PINK1	ENSG00000158828	-0.3465758214952991	[833]	[1387]	-3	hSpCas9	negative selection	2284198
20633572	20633595	1	-	24336569	HL60	viability	CTCGACCCAGCTGCAGGCCGCGG	PINK1	ENSG00000158828	-0.05371050117871412	[797]	[1626]	0	hSpCas9	negative selection	2284199
20633578	20633601	1	-	24336569	HL60	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	1.1166732943379893	[466]	[2142]	8	hSpCas9	negative selection	2284200
20633593	20633616	1	+	24336569	HL60	viability	AGCGCTGCTGCTGCGCTTCACGG	PINK1	ENSG00000158828	0.7733695315955911	[268]	[972]	6	hSpCas9	negative selection	2284201
20633603	20633626	1	+	24336569	HL60	viability	CTGCGCTTCACGGGCAAGCCCGG	PINK1	ENSG00000158828	-0.15249533956131311	[280]	[534]	-1	hSpCas9	negative selection	2284202
20633608	20633631	1	+	24336569	HL60	viability	CTTCACGGGCAAGCCCGGCCGGG	PINK1	ENSG00000158828	0.21610271116432644	[859]	[2113]	2	hSpCas9	negative selection	2284203
20633615	20633638	1	+	24336569	HL60	viability	GGCAAGCCCGGCCGGGCCTACGG	PINK1	ENSG00000158828	-0.054250913939280165	[813]	[1658]	0	hSpCas9	negative selection	2284204
20633542	20633565	1	+	24336569	KBM7	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	1.0405011076263062	[484]	[2720]	8	hSpCas9	negative selection	2351373
20633547	20633570	1	-	24336569	KBM7	viability	CAGCGCCTGTCGCACCGCCATGG	PINK1	ENSG00000158828	0.9941262531920412	[267]	[1455]	8	hSpCas9	negative selection	2351374
20633555	20633578	1	+	24336569	KBM7	viability	GTGCGACAGGCGCTGGGCCGCGG	PINK1	ENSG00000158828	0.9046849767094386	[479]	[2450]	7	hSpCas9	negative selection	2351375
20633572	20633595	1	-	24336569	KBM7	viability	CTCGACCCAGCTGCAGGCCGCGG	PINK1	ENSG00000158828	0.548240287512597	[431]	[1722]	5	hSpCas9	negative selection	2351376
20633578	20633601	1	-	24336569	KBM7	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.8397027555315889	[530]	[2591]	7	hSpCas9	negative selection	2351377
20633593	20633616	1	+	24336569	KBM7	viability	AGCGCTGCTGCTGCGCTTCACGG	PINK1	ENSG00000158828	0.5401424736726809	[412]	[1637]	5	hSpCas9	negative selection	2351378
20633603	20633626	1	+	24336569	KBM7	viability	CTGCGCTTCACGGGCAAGCCCGG	PINK1	ENSG00000158828	0.8523225920084809	[131]	[649]	7	hSpCas9	negative selection	2351379
20633608	20633631	1	+	24336569	KBM7	viability	CTTCACGGGCAAGCCCGGCCGGG	PINK1	ENSG00000158828	0.1368838424948291	[962]	[2887]	1	hSpCas9	negative selection	2351380
20633615	20633638	1	+	24336569	KBM7	viability	GGCAAGCCCGGCCGGGCCTACGG	PINK1	ENSG00000158828	0.8699029933072879	[519]	[2591]	7	hSpCas9	negative selection	2351381
20638010	20638033	1	+	27260157	DLD1	viability	AAGAGCACCGGGTTGCTTCCAGG	PINK1	ENSG00000158828	0.31695185303721	[]	[]	4	hSpCas9	negative selection	2574287
20633615	20633638	1	+	27260157	DLD1	viability	GGCAAGCCCGGCCGGGCCTACGG	PINK1	ENSG00000158828	-0.0579397064940917	[]	[]	0	hSpCas9	negative selection	2574563
20633572	20633595	1	-	27260157	DLD1	viability	CTCGACCCAGCTGCAGGCCGCGG	PINK1	ENSG00000158828	0.164433467104678	[]	[]	3	hSpCas9	negative selection	2582300
20637920	20637943	1	+	27260157	DLD1	viability	TATCTGATAGGGCAGTCCATTGG	PINK1	ENSG00000158828	-0.417688393977316	[]	[]	-3	hSpCas9	negative selection	2586094
20637892	20637915	1	+	27260157	DLD1	viability	ACGCTTGCAGGGCTTTCGGCTGG	PINK1	ENSG00000158828	-1.00945694721381	[]	[]	-7	hSpCas9	negative selection	2608333
20633593	20633616	1	+	27260157	DLD1	viability	AGCGCTGCTGCTGCGCTTCACGG	PINK1	ENSG00000158828	1.12677598136121	[]	[]	9	hSpCas9	negative selection	2610191
20633603	20633626	1	+	27260157	DLD1	viability	CTGCGCTTCACGGGCAAGCCCGG	PINK1	ENSG00000158828	0.750975243472424	[]	[]	8	hSpCas9	negative selection	2616411
20633544	20633567	1	-	27260157	DLD1	viability	CGCCTGTCGCACCGCCATGGTGG	PINK1	ENSG00000158828	-0.127450901558246	[]	[]	-1	hSpCas9	negative selection	2616876
20633608	20633631	1	+	27260157	DLD1	viability	CTTCACGGGCAAGCCCGGCCGGG	PINK1	ENSG00000158828	1.01979381792929	[]	[]	9	hSpCas9	negative selection	2617289
20637908	20637931	1	+	27260157	DLD1	viability	CGGCTGGAGGAGTATCTGATAGG	PINK1	ENSG00000158828	1.26871518140891	[]	[]	9	hSpCas9	negative selection	2619306
20633547	20633570	1	-	27260157	DLD1	viability	CAGCGCCTGTCGCACCGCCATGG	PINK1	ENSG00000158828	-0.611074328944944	[]	[]	-5	hSpCas9	negative selection	2620848
20633542	20633565	1	+	27260157	DLD1	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.0629190566207834	[]	[]	0	hSpCas9	negative selection	2641841
20633578	20633601	1	-	27260157	DLD1	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.468991371660988	[]	[]	8	hSpCas9	negative selection	2642690
20633555	20633578	1	+	27260157	DLD1	viability	GTGCGACAGGCGCTGGGCCGCGG	PINK1	ENSG00000158828	0.604671026970134	[]	[]	8	hSpCas9	negative selection	2644000
20638010	20638033	1	+	27260157	HT1080	viability	AAGAGCACCGGGTTGCTTCCAGG	PINK1	ENSG00000158828	0.577604064115464	[]	[]	5	hSpCas9	negative selection	2650417
20633615	20633638	1	+	27260157	HT1080	viability	GGCAAGCCCGGCCGGGCCTACGG	PINK1	ENSG00000158828	0.233827036872955	[]	[]	2	hSpCas9	negative selection	2650693
20633572	20633595	1	-	27260157	HT1080	viability	CTCGACCCAGCTGCAGGCCGCGG	PINK1	ENSG00000158828	0.883916348979331	[]	[]	7	hSpCas9	negative selection	2658430
20637920	20637943	1	+	27260157	HT1080	viability	TATCTGATAGGGCAGTCCATTGG	PINK1	ENSG00000158828	0.344067144748386	[]	[]	3	hSpCas9	negative selection	2662224
20637892	20637915	1	+	27260157	HT1080	viability	ACGCTTGCAGGGCTTTCGGCTGG	PINK1	ENSG00000158828	-0.606907365987048	[]	[]	-8	hSpCas9	negative selection	2684463
20633593	20633616	1	+	27260157	HT1080	viability	AGCGCTGCTGCTGCGCTTCACGG	PINK1	ENSG00000158828	0.864498124816602	[]	[]	7	hSpCas9	negative selection	2686321
20633603	20633626	1	+	27260157	HT1080	viability	CTGCGCTTCACGGGCAAGCCCGG	PINK1	ENSG00000158828	0.190330907098101	[]	[]	1	hSpCas9	negative selection	2692541
20633544	20633567	1	-	27260157	HT1080	viability	CGCCTGTCGCACCGCCATGGTGG	PINK1	ENSG00000158828	-0.556436666939641	[]	[]	-7	hSpCas9	negative selection	2693006
20633608	20633631	1	+	27260157	HT1080	viability	CTTCACGGGCAAGCCCGGCCGGG	PINK1	ENSG00000158828	0.2932329796645	[]	[]	2	hSpCas9	negative selection	2693419
20637908	20637931	1	+	27260157	HT1080	viability	CGGCTGGAGGAGTATCTGATAGG	PINK1	ENSG00000158828	1.38420467206426	[]	[]	9	hSpCas9	negative selection	2695436
20633547	20633570	1	-	27260157	HT1080	viability	CAGCGCCTGTCGCACCGCCATGG	PINK1	ENSG00000158828	0.14902038189597	[]	[]	1	hSpCas9	negative selection	2696978
20633542	20633565	1	+	27260157	HT1080	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.142825929071004	[]	[]	0	hSpCas9	negative selection	2717971
20633578	20633601	1	-	27260157	HT1080	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.399645635317933	[]	[]	3	hSpCas9	negative selection	2718820
20633555	20633578	1	+	27260157	HT1080	viability	GTGCGACAGGCGCTGGGCCGCGG	PINK1	ENSG00000158828	-0.126608479443674	[]	[]	0	hSpCas9	negative selection	2720130
20638010	20638033	1	+	27260157	MKN45	viability	AAGAGCACCGGGTTGCTTCCAGG	PINK1	ENSG00000158828	1.23359906803592	[]	[]	9	hSpCas9	negative selection	2726547
20633615	20633638	1	+	27260157	MKN45	viability	GGCAAGCCCGGCCGGGCCTACGG	PINK1	ENSG00000158828	0.0971104057496694	[]	[]	0	hSpCas9	negative selection	2726823
20633572	20633595	1	-	27260157	MKN45	viability	CTCGACCCAGCTGCAGGCCGCGG	PINK1	ENSG00000158828	0.216324666933662	[]	[]	5	hSpCas9	negative selection	2734560
20637920	20637943	1	+	27260157	MKN45	viability	TATCTGATAGGGCAGTCCATTGG	PINK1	ENSG00000158828	-0.773806329586565	[]	[]	-7	hSpCas9	negative selection	2738354
20637892	20637915	1	+	27260157	MKN45	viability	ACGCTTGCAGGGCTTTCGGCTGG	PINK1	ENSG00000158828	-0.247685789047553	[]	[]	-1	hSpCas9	negative selection	2760593
20633593	20633616	1	+	27260157	MKN45	viability	AGCGCTGCTGCTGCGCTTCACGG	PINK1	ENSG00000158828	1.93616317451936	[]	[]	9	hSpCas9	negative selection	2762451
20633603	20633626	1	+	27260157	MKN45	viability	CTGCGCTTCACGGGCAAGCCCGG	PINK1	ENSG00000158828	1.5202824695951	[]	[]	9	hSpCas9	negative selection	2768671
20633544	20633567	1	-	27260157	MKN45	viability	CGCCTGTCGCACCGCCATGGTGG	PINK1	ENSG00000158828	1.57668513618802	[]	[]	9	hSpCas9	negative selection	2769136
20633608	20633631	1	+	27260157	MKN45	viability	CTTCACGGGCAAGCCCGGCCGGG	PINK1	ENSG00000158828	0.0422912808087104	[]	[]	0	hSpCas9	negative selection	2769549
20637908	20637931	1	+	27260157	MKN45	viability	CGGCTGGAGGAGTATCTGATAGG	PINK1	ENSG00000158828	0.249759187455625	[]	[]	5	hSpCas9	negative selection	2771566
20633547	20633570	1	-	27260157	MKN45	viability	CAGCGCCTGTCGCACCGCCATGG	PINK1	ENSG00000158828	-0.212711645061471	[]	[]	-1	hSpCas9	negative selection	2773108
20633542	20633565	1	+	27260157	MKN45	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-1.05661353195087	[]	[]	-8	hSpCas9	negative selection	2794101
20633578	20633601	1	-	27260157	MKN45	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	-0.144518695697425	[]	[]	0	hSpCas9	negative selection	2794950
20633555	20633578	1	+	27260157	MKN45	viability	GTGCGACAGGCGCTGGGCCGCGG	PINK1	ENSG00000158828	0.208566073367534	[]	[]	5	hSpCas9	negative selection	2796260
20638010	20638033	1	+	27260157	RKO	viability	AAGAGCACCGGGTTGCTTCCAGG	PINK1	ENSG00000158828	0.627512722977119	[]	[]	3	hSpCas9	negative selection	2802677
20633615	20633638	1	+	27260157	RKO	viability	GGCAAGCCCGGCCGGGCCTACGG	PINK1	ENSG00000158828	-0.497735594506027	[]	[]	-6	hSpCas9	negative selection	2802953
20633572	20633595	1	-	27260157	RKO	viability	CTCGACCCAGCTGCAGGCCGCGG	PINK1	ENSG00000158828	0.286531454249271	[]	[]	1	hSpCas9	negative selection	2810690
20637920	20637943	1	+	27260157	RKO	viability	TATCTGATAGGGCAGTCCATTGG	PINK1	ENSG00000158828	0.521478087990322	[]	[]	2	hSpCas9	negative selection	2814484
20637892	20637915	1	+	27260157	RKO	viability	ACGCTTGCAGGGCTTTCGGCTGG	PINK1	ENSG00000158828	-0.374221011601738	[]	[]	-6	hSpCas9	negative selection	2836723
20633593	20633616	1	+	27260157	RKO	viability	AGCGCTGCTGCTGCGCTTCACGG	PINK1	ENSG00000158828	0.694431882555518	[]	[]	8	hSpCas9	negative selection	2838581
20633603	20633626	1	+	27260157	RKO	viability	CTGCGCTTCACGGGCAAGCCCGG	PINK1	ENSG00000158828	0.694823376314937	[]	[]	8	hSpCas9	negative selection	2844801
20633544	20633567	1	-	27260157	RKO	viability	CGCCTGTCGCACCGCCATGGTGG	PINK1	ENSG00000158828	-0.29079060325458	[]	[]	-6	hSpCas9	negative selection	2845266
20633608	20633631	1	+	27260157	RKO	viability	CTTCACGGGCAAGCCCGGCCGGG	PINK1	ENSG00000158828	0.671887149026039	[]	[]	7	hSpCas9	negative selection	2845679
20637908	20637931	1	+	27260157	RKO	viability	CGGCTGGAGGAGTATCTGATAGG	PINK1	ENSG00000158828	0.315835056146474	[]	[]	1	hSpCas9	negative selection	2847696
20633547	20633570	1	-	27260157	RKO	viability	CAGCGCCTGTCGCACCGCCATGG	PINK1	ENSG00000158828	0.437527400806596	[]	[]	2	hSpCas9	negative selection	2849238
20633542	20633565	1	+	27260157	RKO	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.637261826813839	[]	[]	-7	hSpCas9	negative selection	2870231
20633578	20633601	1	-	27260157	RKO	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.229219653211955	[]	[]	1	hSpCas9	negative selection	2871080
20633555	20633578	1	+	27260157	RKO	viability	GTGCGACAGGCGCTGGGCCGCGG	PINK1	ENSG00000158828	-0.365717283860502	[]	[]	-6	hSpCas9	negative selection	2872390
20638010	20638033	1	+	27260157	SF268	viability	AAGAGCACCGGGTTGCTTCCAGG	PINK1	ENSG00000158828	0.139202517095041	[]	[]	0	hSpCas9	negative selection	2878807
20633615	20633638	1	+	27260157	SF268	viability	GGCAAGCCCGGCCGGGCCTACGG	PINK1	ENSG00000158828	-0.257162892730493	[]	[]	-2	hSpCas9	negative selection	2879083
20633572	20633595	1	-	27260157	SF268	viability	CTCGACCCAGCTGCAGGCCGCGG	PINK1	ENSG00000158828	0.780228063018255	[]	[]	8	hSpCas9	negative selection	2886820
20637920	20637943	1	+	27260157	SF268	viability	TATCTGATAGGGCAGTCCATTGG	PINK1	ENSG00000158828	0.245768488983797	[]	[]	3	hSpCas9	negative selection	2890614
20637892	20637915	1	+	27260157	SF268	viability	ACGCTTGCAGGGCTTTCGGCTGG	PINK1	ENSG00000158828	-0.865091792057655	[]	[]	-6	hSpCas9	negative selection	2912853
20633593	20633616	1	+	27260157	SF268	viability	AGCGCTGCTGCTGCGCTTCACGG	PINK1	ENSG00000158828	0.456285737960558	[]	[]	7	hSpCas9	negative selection	2914711
20633603	20633626	1	+	27260157	SF268	viability	CTGCGCTTCACGGGCAAGCCCGG	PINK1	ENSG00000158828	1.32498646946382	[]	[]	9	hSpCas9	negative selection	2920931
20633544	20633567	1	-	27260157	SF268	viability	CGCCTGTCGCACCGCCATGGTGG	PINK1	ENSG00000158828	0.913365813706155	[]	[]	9	hSpCas9	negative selection	2921396
20633608	20633631	1	+	27260157	SF268	viability	CTTCACGGGCAAGCCCGGCCGGG	PINK1	ENSG00000158828	0.269196011372612	[]	[]	4	hSpCas9	negative selection	2921809
20637908	20637931	1	+	27260157	SF268	viability	CGGCTGGAGGAGTATCTGATAGG	PINK1	ENSG00000158828	-0.0219030388971104	[]	[]	0	hSpCas9	negative selection	2923826
20633547	20633570	1	-	27260157	SF268	viability	CAGCGCCTGTCGCACCGCCATGG	PINK1	ENSG00000158828	-0.229566044620447	[]	[]	-2	hSpCas9	negative selection	2925368
20633542	20633565	1	+	27260157	SF268	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.86138519726821	[]	[]	-6	hSpCas9	negative selection	2946361
20633578	20633601	1	-	27260157	SF268	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.7892669606261	[]	[]	8	hSpCas9	negative selection	2947210
20633555	20633578	1	+	27260157	SF268	viability	GTGCGACAGGCGCTGGGCCGCGG	PINK1	ENSG00000158828	-0.487522096581837	[]	[]	-4	hSpCas9	negative selection	2948520
20637927	20637950	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	-0.2212641892293028	[3,3]	[2,2]	-3	hSpCas9	positive selection	3011435
20633876	20633899	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCATCGAGGAAAAACAGGCGG	PINK1	ENSG00000158828	-0.5663964332159406	[2,3]	[0,1]	-7	hSpCas9	positive selection	3011436
20637850	20637873	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-0.22398045544906192	[2,2]	[2,0]	-3	hSpCas9	positive selection	3011437
20637927	20637950	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	-0.6890172284490523	[3,3]	[2,0]	-8	hSpCas9	positive selection	3079293
20633876	20633899	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCATCGAGGAAAAACAGGCGG	PINK1	ENSG00000158828	0.028869085578124787	[2,2]	[3,1]	0	hSpCas9	positive selection	3079294
20637850	20637873	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-0.6754658584374141	[2,2]	[0,0]	-8	hSpCas9	positive selection	3079295
20633542	20633565		+	24336571	A375	resistance to PLX after 7 days	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.2253343018592493	[9,8]	[6,8]	-7	hSpCas9	positive selection	3135702
20633542	20633565		+	24336571	A375	resistance to PLX after 14 days	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-1.33476709218562	[8,13]	[1,1]	-9	hSpCas9	positive selection	3193495
20633542	20633565		+	24336571	A375	viability after 7 days	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.7259823512403446	[5]	[9,8]	9	hSpCas9	negative selection	3251288
20633542	20633565		+	24336571	A375	viability after 14 days	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.9403734638454466	[5]	[8,13]	9	hSpCas9	negative selection	3309081
20637878	20637901	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-1.2464995265499157	[362,362]	[0,0]	-8	hSpCas9	positive selection	3385935
20637880	20637903	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	3.087401210003523	[17,17]	[0,0]	8	hSpCas9	positive selection	3385936
20637926	20637949	1	+	26780180	HT29	viability (Avana library 4 designs)	ATAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	0.0450815023124328	[]	[]	0	hSpCas9	negative selection	3449522
20633875	20633898	1	+	26780180	HT29	viability (Avana library 4 designs)	CCTCATCGAGGAAAAACAGGCGG	PINK1	ENSG00000158828	1.80989991719352	[]	[]	7	hSpCas9	negative selection	3449523
20637849	20637872	1	+	26780180	HT29	viability (Avana library 4 designs)	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	1.79112932958978	[]	[]	6	hSpCas9	negative selection	3449524
20637849	20637872	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-2.33755479311851	[]	[]	-3	hSpCas9	negative selection	3544323
20633875	20633898	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCATCGAGGAAAAACAGGCGG	PINK1	ENSG00000158828	-8.29562707063481	[]	[]	-7	hSpCas9	negative selection	3544324
20637926	20637949	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	1.88900344066635	[]	[]	2	hSpCas9	negative selection	3544325
20638044	20638067	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTACCAGTGCACCAGGAGAAGGG	PINK1	ENSG00000158828	3.36060262406536	[]	[]	5	hSpCas9	negative selection	3544326
20633839	20633862	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGAAGGCCAGAAAGACTGCCCGG	PINK1	ENSG00000158828	4.7467094952624	[]	[]	7	hSpCas9	negative selection	3544327
20637849	20637872	1	+	26780180	A375	viability (Avana lentiGuide)	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	11.3048287624423	[]	[]	7	hSpCas9	negative selection	3652982
20633875	20633898	1	+	26780180	A375	viability (Avana lentiGuide)	CCTCATCGAGGAAAAACAGGCGG	PINK1	ENSG00000158828	-6.88610406543148	[]	[]	-9	hSpCas9	negative selection	3652983
20637926	20637949	1	+	26780180	A375	viability (Avana lentiGuide)	ATAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	3.39642841715513	[]	[]	3	hSpCas9	negative selection	3652984
20638044	20638067	1	+	26780180	A375	viability (Avana lentiGuide)	GTACCAGTGCACCAGGAGAAGGG	PINK1	ENSG00000158828	9.72425708122571	[]	[]	6	hSpCas9	negative selection	3652985
20633839	20633862	1	-	26780180	A375	viability (Avana lentiGuide)	CGAAGGCCAGAAAGACTGCCCGG	PINK1	ENSG00000158828	-3.16742732966291	[]	[]	-5	hSpCas9	negative selection	3652986
20637849	20637872	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-0.3991585145831838	[4]	[3,2]	-5	hSpCas9	positive selection	3761641
20633875	20633898	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCATCGAGGAAAAACAGGCGG	PINK1	ENSG00000158828	-0.22867324108805737	[4]	[2,3]	-4	hSpCas9	positive selection	3761642
20637926	20637949	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	0.17437602074854958	[5]	[6,6]	5	hSpCas9	positive selection	3761643
20638044	20638067	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACCAGTGCACCAGGAGAAGGG	PINK1	ENSG00000158828	0.249307962683674	[4]	[6,5]	7	hSpCas9	positive selection	3761644
20633839	20633862	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAAGGCCAGAAAGACTGCCCGG	PINK1	ENSG00000158828	0.29776840700660534	[5]	[6,6]	8	hSpCas9	positive selection	3761645
20637849	20637872	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-0.7319935821299604	[4]	[1,1]	-7	hSpCas9	positive selection	3870248
20633875	20633898	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCATCGAGGAAAAACAGGCGG	PINK1	ENSG00000158828	-0.23393616021724134	[4]	[4,1]	-3	hSpCas9	positive selection	3870249
20637926	20637949	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	-0.0017189902775519795	[5]	[3,5]	0	hSpCas9	positive selection	3870250
20638044	20638067	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACCAGTGCACCAGGAGAAGGG	PINK1	ENSG00000158828	-0.07467043714635213	[5]	[3,4]	-1	hSpCas9	positive selection	3870251
20633839	20633862	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAAGGCCAGAAAGACTGCCCGG	PINK1	ENSG00000158828	0.30830850838782814	[6]	[7,6]	8	hSpCas9	positive selection	3870252
20633542	20633565	1	+	26780180	A375	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.599330537389809	[]	[]	1	hSpCas9	negative selection	3981063
20637880	20637903	1	+	26780180	A375	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.252015982649234	[]	[]	0	hSpCas9	negative selection	3981064
20637878	20637901	1	-	26780180	A375	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.553212387064934	[]	[]	1	hSpCas9	negative selection	3981065
20633542	20633565	1	+	26780180	HT29	viability (GeCKOv2 library)	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	1.25807091273962	[]	[]	6	hSpCas9	negative selection	4089029
20637880	20637903	1	+	26780180	HT29	viability (GeCKOv2 library)	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.740533219358222	[]	[]	3	hSpCas9	negative selection	4089030
20637878	20637901	1	-	26780180	HT29	viability (GeCKOv2 library)	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.674006473673657	[]	[]	2	hSpCas9	negative selection	4089031
20633542	20633565	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.3019542766076331	[2]	[1,0]	-6	hSpCas9	positive selection	4160656
20633542	20633565	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.21353314140219018	[3]	[2,2,1,0]	1	hSpCas9	positive selection	4224678
20633542	20633565	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.22191763152999755	[1]	[1,1]	4	hSpCas9	positive selection	4290339
20637878	20637901	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.09523605847313038	[4]	[3,2]	2	hSpCas9	positive selection	4354592
20637880	20637903	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.1784034833266146	[0]	[1,0]	3	hSpCas9	positive selection	4354593
20633831	20633853	1	-	27760321	OCIAML3	viability	GAAAGACTGCCCGGCCGCAAGG	PINK1	ENSG00000158828	0.5551736332305248	[1002,751]	[853,1189]	6	hSpCas9	negative selection	4427934
20637872	20637894	1	-	27760321	OCIAML3	viability	GTCTCGTGTCCAACGGGTCAGG	PINK1	ENSG00000158828	-0.14156572334322537	[759,728]	[486,582]	-1	hSpCas9	negative selection	4427935
20637927	20637949	1	+	27760321	OCIAML3	viability	TAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	0.8250921236328681	[204,164]	[273,229]	8	hSpCas9	negative selection	4427936
20637975	20637997	1	-	27760321	OCIAML3	viability	TTCTGGGGCAATGTAGGCATGG	PINK1	ENSG00000158828	0.350732702896929	[450,415]	[473,377]	4	hSpCas9	negative selection	4427937
20639937	20639959	1	+	27760321	OCIAML3	viability	CTGGTCCCAGCGAGCCGAGTGG	PINK1	ENSG00000158828	0.48216449218119295	[387,423]	[443,449]	6	hSpCas9	negative selection	4427938
20633831	20633853	1	-	27760321	OCIAML2	viability	GAAAGACTGCCCGGCCGCAAGG	PINK1	ENSG00000158828	0.36185716277822233	[1002,751]	[932,866]	5	hSpCas9	negative selection	4511397
20637872	20637894	1	-	27760321	OCIAML2	viability	GTCTCGTGTCCAACGGGTCAGG	PINK1	ENSG00000158828	0.1782685228996045	[759,728]	[600,789]	2	hSpCas9	negative selection	4511398
20637927	20637949	1	+	27760321	OCIAML2	viability	TAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	0.5001661422422166	[204,164]	[159,276]	6	hSpCas9	negative selection	4511399
20637975	20637997	1	-	27760321	OCIAML2	viability	TTCTGGGGCAATGTAGGCATGG	PINK1	ENSG00000158828	0.42428293698961317	[450,415]	[511,415]	6	hSpCas9	negative selection	4511400
20639937	20639959	1	+	27760321	OCIAML2	viability	CTGGTCCCAGCGAGCCGAGTGG	PINK1	ENSG00000158828	0.1801298838431534	[387,423]	[356,397]	2	hSpCas9	negative selection	4511401
20633831	20633853	1	-	27760321	MV411	viability	GAAAGACTGCCCGGCCGCAAGG	PINK1	ENSG00000158828	0.16816377508356806	[1002,751]	[342,1098]	1	hSpCas9	negative selection	4594860
20637872	20637894	1	-	27760321	MV411	viability	GTCTCGTGTCCAACGGGTCAGG	PINK1	ENSG00000158828	-1.2515233199042275	[759,728]	[51,438]	-7	hSpCas9	negative selection	4594861
20637927	20637949	1	+	27760321	MV411	viability	TAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	0.4171648821116415	[204,164]	[46,334]	3	hSpCas9	negative selection	4594862
20637975	20637997	1	-	27760321	MV411	viability	TTCTGGGGCAATGTAGGCATGG	PINK1	ENSG00000158828	0.829774948586632	[450,415]	[559,430]	6	hSpCas9	negative selection	4594863
20639937	20639959	1	+	27760321	MV411	viability	CTGGTCCCAGCGAGCCGAGTGG	PINK1	ENSG00000158828	0.030423236056144526	[387,423]	[183,412]	0	hSpCas9	negative selection	4594864
20633831	20633853	1	-	27760321	HL60	viability	GAAAGACTGCCCGGCCGCAAGG	PINK1	ENSG00000158828	0.2811049727278747	[1002,751]	[967,752]	3	hSpCas9	negative selection	4678323
20637872	20637894	1	-	27760321	HL60	viability	GTCTCGTGTCCAACGGGTCAGG	PINK1	ENSG00000158828	-0.016248660736983056	[759,728]	[545,661]	0	hSpCas9	negative selection	4678324
20637927	20637949	1	+	27760321	HL60	viability	TAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	0.5580823377665003	[204,164]	[295,141]	6	hSpCas9	negative selection	4678325
20637975	20637997	1	-	27760321	HL60	viability	TTCTGGGGCAATGTAGGCATGG	PINK1	ENSG00000158828	0.022776279697903266	[450,415]	[317,403]	0	hSpCas9	negative selection	4678326
20639937	20639959	1	+	27760321	HL60	viability	CTGGTCCCAGCGAGCCGAGTGG	PINK1	ENSG00000158828	0.5169307621064113	[387,423]	[505,447]	6	hSpCas9	negative selection	4678327
20633831	20633853	1	-	27760321	HT1080	viability	GAAAGACTGCCCGGCCGCAAGG	PINK1	ENSG00000158828	1.3689822917583938	[751,586]	[833,529]	7	hSpCas9	negative selection	4761786
20637872	20637894	1	-	27760321	HT1080	viability	GTCTCGTGTCCAACGGGTCAGG	PINK1	ENSG00000158828	-0.8414447234966796	[728,568]	[44,252]	-4	hSpCas9	negative selection	4761787
20637927	20637949	1	+	27760321	HT1080	viability	TAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	3.4325975533868416	[164,128]	[776,473]	9	hSpCas9	negative selection	4761788
20637975	20637997	1	-	27760321	HT1080	viability	TTCTGGGGCAATGTAGGCATGG	PINK1	ENSG00000158828	0.6578498141239488	[415,324]	[261,200]	3	hSpCas9	negative selection	4761789
20639937	20639959	1	+	27760321	HT1080	viability	CTGGTCCCAGCGAGCCGAGTGG	PINK1	ENSG00000158828	0.23134203739898918	[423,330]	[187,163]	1	hSpCas9	negative selection	4761790
20633831	20633853	1	-	27760321	HT29	viability after 7 days	GAAAGACTGCCCGGCCGCAAGG	PINK1	ENSG00000158828	0.3460028656897437	[751,586]	[1081,1039,1154]	5	hSpCas9	negative selection	4845249
20637872	20637894	1	-	27760321	HT29	viability after 7 days	GTCTCGTGTCCAACGGGTCAGG	PINK1	ENSG00000158828	0.07884679974836528	[728,568]	[1058,823,787]	1	hSpCas9	negative selection	4845250
20637927	20637949	1	+	27760321	HT29	viability after 7 days	TAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	0.5671581433932933	[164,128]	[420,258,182]	8	hSpCas9	negative selection	4845251
20637975	20637997	1	-	27760321	HT29	viability after 7 days	TTCTGGGGCAATGTAGGCATGG	PINK1	ENSG00000158828	-0.23249664737089182	[415,324]	[396,486,332]	-3	hSpCas9	negative selection	4845252
20639937	20639959	1	+	27760321	HT29	viability after 7 days	CTGGTCCCAGCGAGCCGAGTGG	PINK1	ENSG00000158828	0.007956664196309055	[423,330]	[525,554,390]	0	hSpCas9	negative selection	4845253
20633831	20633853	1	-	27760321	HT29	viability after 25 days	GAAAGACTGCCCGGCCGCAAGG	PINK1	ENSG00000158828	0.6791595499967592	[751,586]	[1138,1391,1138]	7	hSpCas9	negative selection	4928712
20637872	20637894	1	-	27760321	HT29	viability after 25 days	GTCTCGTGTCCAACGGGTCAGG	PINK1	ENSG00000158828	-0.0835761312763833	[728,568]	[552,596,987]	-1	hSpCas9	negative selection	4928713
20637927	20637949	1	+	27760321	HT29	viability after 25 days	TAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	0.25633762604432686	[164,128]	[108,353,137]	2	hSpCas9	negative selection	4928714
20637975	20637997	1	-	27760321	HT29	viability after 25 days	TTCTGGGGCAATGTAGGCATGG	PINK1	ENSG00000158828	0.11017255361089422	[415,324]	[280,492,624]	1	hSpCas9	negative selection	4928715
20639937	20639959	1	+	27760321	HT29	viability after 25 days	CTGGTCCCAGCGAGCCGAGTGG	PINK1	ENSG00000158828	0.22234387892235175	[423,330]	[470,417,635]	2	hSpCas9	negative selection	4928716
20633831	20633853	1	-	27760321	HT29	viability after 22 days	GAAAGACTGCCCGGCCGCAAGG	PINK1	ENSG00000158828	0.7037648820420702	[751,586]	[1180,1652,946]	7	hSpCas9	negative selection	5012175
20637872	20637894	1	-	27760321	HT29	viability after 22 days	GTCTCGTGTCCAACGGGTCAGG	PINK1	ENSG00000158828	-0.0838330022074284	[728,568]	[674,598,851]	-1	hSpCas9	negative selection	5012176
20637927	20637949	1	+	27760321	HT29	viability after 22 days	TAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	0.7053051543563438	[164,128]	[272,222,335]	7	hSpCas9	negative selection	5012177
20637975	20637997	1	-	27760321	HT29	viability after 22 days	TTCTGGGGCAATGTAGGCATGG	PINK1	ENSG00000158828	-0.17613685115972744	[415,324]	[314,450,372]	-2	hSpCas9	negative selection	5012178
20639937	20639959	1	+	27760321	HT29	viability after 22 days	CTGGTCCCAGCGAGCCGAGTGG	PINK1	ENSG00000158828	0.1915788921737716	[423,330]	[499,403,591]	2	hSpCas9	negative selection	5012179
20633831	20633853	1	-	27760321	HT29	viability after 19 days	GAAAGACTGCCCGGCCGCAAGG	PINK1	ENSG00000158828	0.5656594748942513	[751,586]	[1278,1421,728]	5	hSpCas9	negative selection	5095638
20637872	20637894	1	-	27760321	HT29	viability after 19 days	GTCTCGTGTCCAACGGGTCAGG	PINK1	ENSG00000158828	0.1384627891354524	[728,568]	[739,578,1111]	1	hSpCas9	negative selection	5095639
20637927	20637949	1	+	27760321	HT29	viability after 19 days	TAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	1.1687856617075936	[164,128]	[328,564,239]	9	hSpCas9	negative selection	5095640
20637975	20637997	1	-	27760321	HT29	viability after 19 days	TTCTGGGGCAATGTAGGCATGG	PINK1	ENSG00000158828	0.3756005504841379	[415,324]	[476,417,738]	3	hSpCas9	negative selection	5095641
20639937	20639959	1	+	27760321	HT29	viability after 19 days	CTGGTCCCAGCGAGCCGAGTGG	PINK1	ENSG00000158828	-0.29531680264274196	[423,330]	[460,235,368]	-3	hSpCas9	negative selection	5095642
20633831	20633853	1	-	27760321	HT29	viability after 16 days	GAAAGACTGCCCGGCCGCAAGG	PINK1	ENSG00000158828	0.7416817478083614	[751,586]	[1483,1143,1153]	8	hSpCas9	negative selection	5179101
20637872	20637894	1	-	27760321	HT29	viability after 16 days	GTCTCGTGTCCAACGGGTCAGG	PINK1	ENSG00000158828	-0.2279174410662571	[728,568]	[697,859,302]	-3	hSpCas9	negative selection	5179102
20637927	20637949	1	+	27760321	HT29	viability after 16 days	TAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	0.5980984049805035	[164,128]	[194,202,344]	7	hSpCas9	negative selection	5179103
20637975	20637997	1	-	27760321	HT29	viability after 16 days	TTCTGGGGCAATGTAGGCATGG	PINK1	ENSG00000158828	0.10664641595955802	[415,324]	[225,413,678]	1	hSpCas9	negative selection	5179104
20639937	20639959	1	+	27760321	HT29	viability after 16 days	CTGGTCCCAGCGAGCCGAGTGG	PINK1	ENSG00000158828	0.45772194158444696	[423,330]	[549,396,794]	5	hSpCas9	negative selection	5179105
20633831	20633853	1	-	27760321	HT29	viability after 13 days	GAAAGACTGCCCGGCCGCAAGG	PINK1	ENSG00000158828	0.7506933123248286	[751,586]	[902,1722,1295]	8	hSpCas9	negative selection	5262564
20637872	20637894	1	-	27760321	HT29	viability after 13 days	GTCTCGTGTCCAACGGGTCAGG	PINK1	ENSG00000158828	0.08429701229162834	[728,568]	[726,789,872]	1	hSpCas9	negative selection	5262565
20637927	20637949	1	+	27760321	HT29	viability after 13 days	TAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	0.7479804149192517	[164,128]	[343,345,175]	8	hSpCas9	negative selection	5262566
20637975	20637997	1	-	27760321	HT29	viability after 13 days	TTCTGGGGCAATGTAGGCATGG	PINK1	ENSG00000158828	0.26835929466675246	[415,324]	[278,677,591]	3	hSpCas9	negative selection	5262567
20639937	20639959	1	+	27760321	HT29	viability after 13 days	CTGGTCCCAGCGAGCCGAGTGG	PINK1	ENSG00000158828	0.33953539525865684	[423,330]	[627,544,492]	4	hSpCas9	negative selection	5262568
20633831	20633853	1	-	27760321	HT29	viability after 10 days	GAAAGACTGCCCGGCCGCAAGG	PINK1	ENSG00000158828	0.610543610093608	[751,586]	[1002,1624,1211]	8	hSpCas9	negative selection	5346027
20637872	20637894	1	-	27760321	HT29	viability after 10 days	GTCTCGTGTCCAACGGGTCAGG	PINK1	ENSG00000158828	0.32927209675184865	[728,568]	[1120,730,1189]	4	hSpCas9	negative selection	5346028
20637927	20637949	1	+	27760321	HT29	viability after 10 days	TAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	0.4267056816626281	[164,128]	[234,268,236]	6	hSpCas9	negative selection	5346029
20637975	20637997	1	-	27760321	HT29	viability after 10 days	TTCTGGGGCAATGTAGGCATGG	PINK1	ENSG00000158828	0.39787315813771457	[415,324]	[738,621,470]	5	hSpCas9	negative selection	5346030
20639937	20639959	1	+	27760321	HT29	viability after 10 days	CTGGTCCCAGCGAGCCGAGTGG	PINK1	ENSG00000158828	-0.20176249769844315	[423,330]	[433,370,422]	-3	hSpCas9	negative selection	5346031
20633831	20633853	1	-	27760321	MOLM13	viability	GAAAGACTGCCCGGCCGCAAGG	PINK1	ENSG00000158828	1.3820166196177104	[1002,751]	[1313,1249]	8	hSpCas9	negative selection	5429490
20637872	20637894	1	-	27760321	MOLM13	viability	GTCTCGTGTCCAACGGGTCAGG	PINK1	ENSG00000158828	0.5476899558445366	[759,728]	[675,562]	4	hSpCas9	negative selection	5429491
20637927	20637949	1	+	27760321	MOLM13	viability	TAGGGCAGTCCATTGGTAAGGG	PINK1	ENSG00000158828	0.17493411624195887	[204,164]	[208,38]	1	hSpCas9	negative selection	5429492
20637975	20637997	1	-	27760321	MOLM13	viability	TTCTGGGGCAATGTAGGCATGG	PINK1	ENSG00000158828	1.446551124374241	[450,415]	[893,472]	8	hSpCas9	negative selection	5429493
20639937	20639959	1	+	27760321	MOLM13	viability	CTGGTCCCAGCGAGCCGAGTGG	PINK1	ENSG00000158828	1.027209100042711	[387,423]	[468,470]	7	hSpCas9	negative selection	5429494
20633533	20633556	1	+	27661255	K562	viability	GGGCCGCGGCGCCACCATGGCGG	PINK1	ENSG00000158828	-0.08826232537780154	[1106,1301]	[950,860]	-3	dCas9-KRAB	negative selection	5501989
20633943	20633966	1	+	27661255	K562	viability	GGGCCGGGTCCTAAGCCGAGCGG	PINK1	ENSG00000158828	0.15952823411197764	[457,609]	[534,421]	5	dCas9-KRAB	negative selection	5501990
20633902	20633925	1	-	27661255	K562	viability	GACAGGCCGAGACCGCCCGCCGG	PINK1	ENSG00000158828	0.0564104044815604	[852,773]	[792,577]	2	dCas9-KRAB	negative selection	5501991
20633919	20633942	1	-	27661255	K562	viability	GCTCACCTGGATCTCCTGACAGG	PINK1	ENSG00000158828	0.06398371392237179	[249,195]	[179,192]	2	dCas9-KRAB	negative selection	5501992
20633542	20633565	1	+	27260156	BXPC3	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.08654952267663218	[142]	[77,118,246,208]	2	hSpCas9	negative selection	5562799
20637878	20637901	1	-	27260156	BXPC3	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.10418004949770654	[1062]	[1068,993,964,1106]	-2	hSpCas9	negative selection	5627052
20637880	20637903	1	+	27260156	BXPC3	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.4442489078119527	[43]	[43,74,47,86]	8	hSpCas9	negative selection	5627053
20633542	20633565	1	+	27260156	A673	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.04756852521272448	[142]	[156,224,148,174]	1	hSpCas9	negative selection	5684050
20637878	20637901	1	-	27260156	A673	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.07420240995531158	[1062]	[1301,1093,1137,1333]	-2	hSpCas9	negative selection	5748303
20637880	20637903	1	+	27260156	A673	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.015694396973712	[43]	[53,51,23,80]	0	hSpCas9	negative selection	5748304
20633542	20633565	1	+	27260156	A375	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.10533035725551487	[142]	[161,245,73,237]	1	hSpCas9	negative selection	5805301
20637878	20637901	1	-	27260156	A375	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.09599400089971777	[1062]	[1031,1687,1023,990]	-1	hSpCas9	negative selection	5869554
20637880	20637903	1	+	27260156	A375	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.7395049063374706	[43]	[102,40,145,50]	9	hSpCas9	negative selection	5869555
20633542	20633565	1	+	27260156	COLO741	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.048955385034249455	[142]	[179,148,198]	-1	hSpCas9	negative selection	5926552
20637878	20637901	1	-	27260156	COLO741	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.1299917092828331	[1062]	[1324,1388,1029]	-3	hSpCas9	negative selection	5990805
20637880	20637903	1	+	27260156	COLO741	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.11175505333548719	[43]	[34,3,110]	-2	hSpCas9	negative selection	5990806
20633542	20633565	1	+	27260156	CAL120	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.6556971963110851	[142]	[67,147,115]	-7	hSpCas9	negative selection	6047803
20637878	20637901	1	-	27260156	CAL120	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.22104959022240522	[1062]	[1306,1041,1081]	-3	hSpCas9	negative selection	6112056
20637880	20637903	1	+	27260156	CAL120	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.28660342018032425	[43]	[100,10,92]	4	hSpCas9	negative selection	6112057
20633542	20633565	1	+	27260156	CADOES1	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.3178368447541233	[142]	[155,112,202,191]	5	hSpCas9	negative selection	6169054
20637878	20637901	1	-	27260156	CADOES1	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.17006609272403517	[1062]	[1097,998,1115,1240]	3	hSpCas9	negative selection	6233307
20637880	20637903	1	+	27260156	CADOES1	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.20946738490453054	[43]	[74,37,58,15]	3	hSpCas9	negative selection	6233308
20633542	20633565	1	+	27260156	EWS502	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.02159443439939146	[142]	[147,177,66,224]	0	hSpCas9	negative selection	6290305
20637878	20637901	1	-	27260156	EWS502	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.05766009493384616	[1062]	[1481,1048,781,1343]	1	hSpCas9	negative selection	6354558
20637880	20637903	1	+	27260156	EWS502	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.06357019389507501	[43]	[56,3,20,99]	-1	hSpCas9	negative selection	6354559
20633542	20633565	1	+	27260156	EW8	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.38250815933900917	[142]	[210,176,131,93]	7	hSpCas9	negative selection	6411556
20637878	20637901	1	-	27260156	EW8	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.04814871734033055	[1062]	[1103,817,807,634]	-1	hSpCas9	negative selection	6475809
20637880	20637903	1	+	27260156	EW8	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.14916492698438866	[43]	[44,9,48,22]	-3	hSpCas9	negative selection	6475810
20633542	20633565	1	+	27260156	CORL105	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.2520814439161114	[142]	[209,118,273,207]	5	hSpCas9	negative selection	6532807
20637878	20637901	1	-	27260156	CORL105	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.1815771236567123	[1062]	[1241,1362,1641,1428]	3	hSpCas9	negative selection	6597060
20637880	20637903	1	+	27260156	CORL105	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.0747640962759859	[43]	[70,79,23,16]	-1	hSpCas9	negative selection	6597061
20633542	20633565	1	+	27260156	HS294T	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.38093053234642094	[142]	[65,76,88,52]	5	hSpCas9	negative selection	6654058
20637878	20637901	1	-	27260156	HS294T	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.16461317562852318	[1062]	[294,636,409,518]	2	hSpCas9	negative selection	6718311
20637880	20637903	1	+	27260156	HS294T	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.11327442077028982	[43]	[27,9,20,12]	1	hSpCas9	negative selection	6718312
20633542	20633565	1	+	27260156	HCC44	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.2867707235468635	[142]	[110,163,135,112]	-4	hSpCas9	negative selection	6775309
20637878	20637901	1	-	27260156	HCC44	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.0074721203062060315	[1062]	[1534,1009,1164,1118]	0	hSpCas9	negative selection	6839562
20637880	20637903	1	+	27260156	HCC44	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.036838630863908595	[43]	[38,53,73,29]	0	hSpCas9	negative selection	6839563
20633542	20633565	1	+	27260156	G402	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.47603211101464726	[142]	[217,68,132,92]	-5	hSpCas9	negative selection	6896560
20637878	20637901	1	-	27260156	G402	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.3554185842369396	[1062]	[1137,1003,1022,908]	-4	hSpCas9	negative selection	6960813
20637880	20637903	1	+	27260156	G402	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.3161676898366892	[43]	[15,65,28,57]	-4	hSpCas9	negative selection	6960814
20633542	20633565	1	+	27260156	L33	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.4211767590579938	[142]	[193,95,105,168]	8	hSpCas9	negative selection	7017811
20637878	20637901	1	-	27260156	L33	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.020515466806071858	[1062]	[1087,385,722,1131]	0	hSpCas9	negative selection	7082064
20637880	20637903	1	+	27260156	L33	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.15991569506872683	[43]	[17,30,50,22]	3	hSpCas9	negative selection	7082065
20633542	20633565	1	+	27260156	K562	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.5318293736747677	[142]	[102,114,90,48]	-6	hSpCas9	negative selection	7139062
20637878	20637901	1	-	27260156	K562	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.10179732388651841	[1062]	[1256,626,1075,1076]	1	hSpCas9	negative selection	7203315
20637880	20637903	1	+	27260156	K562	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.9185275523162875	[43]	[4,50,232,6]	9	hSpCas9	negative selection	7203316
20633542	20633565	1	+	27260156	HT29	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.12160526657503312	[142]	[98,187,65,268]	-3	hSpCas9	negative selection	7260313
20637878	20637901	1	-	27260156	HT29	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.06196182900674985	[1062]	[1412,1491,1303,820]	-1	hSpCas9	negative selection	7324566
20637880	20637903	1	+	27260156	HT29	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.6079276066214807	[43]	[24,8,75,27]	-7	hSpCas9	negative selection	7324567
20633542	20633565	1	+	27260156	MHHES1	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.26503780679554323	[142]	[139,146,159,96]	-5	hSpCas9	negative selection	7381564
20637878	20637901	1	-	27260156	MHHES1	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.19789452640519556	[1062]	[1279,980,1333,668]	-4	hSpCas9	negative selection	7445817
20637880	20637903	1	+	27260156	MHHES1	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.17120571940480334	[43]	[35,59,52,67]	3	hSpCas9	negative selection	7445818
20633542	20633565	1	+	27260156	MEWO	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.42910963473079233	[142]	[108,86,103]	-7	hSpCas9	negative selection	7502815
20637878	20637901	1	-	27260156	MEWO	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.27448033948561523	[1062]	[1016,650,836]	-5	hSpCas9	negative selection	7567068
20637880	20637903	1	+	27260156	MEWO	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.28519505129935707	[43]	[41,18,41]	-6	hSpCas9	negative selection	7567069
20633542	20633565	1	+	27260156	LNCAPCLONEFGC	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.28287745770212136	[142]	[112,130,105,73]	-4	hSpCas9	negative selection	7624066
20637878	20637901	1	-	27260156	LNCAPCLONEFGC	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.008184326971441669	[1062]	[1171,637,1110,990]	0	hSpCas9	negative selection	7688319
20637880	20637903	1	+	27260156	LNCAPCLONEFGC	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.28485970433970786	[43]	[28,45,18,33]	-4	hSpCas9	negative selection	7688320
20633542	20633565	1	+	27260156	PANC0327	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.27743293424604243	[142]	[112,242,156,87]	4	hSpCas9	negative selection	7745317
20637878	20637901	1	-	27260156	PANC0327	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.07641738554497746	[1062]	[927,677,1082,923]	-1	hSpCas9	negative selection	7809570
20637880	20637903	1	+	27260156	PANC0327	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.0068481460561899965	[43]	[37,34,31,50]	0	hSpCas9	negative selection	7809571
20633542	20633565	1	+	27260156	NCIH2009	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.8205466420485507	[142]	[397,345,322]	9	hSpCas9	negative selection	7866568
20637878	20637901	1	-	27260156	NCIH2009	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.08516911061366716	[1062]	[1903,1450,1435]	1	hSpCas9	negative selection	7930821
20637880	20637903	1	+	27260156	NCIH2009	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.9727790162824173	[43]	[63,95,190]	9	hSpCas9	negative selection	7930822
20633542	20633565	1	+	27260156	NCIH1373	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-1.0092754105805128	[142]	[50,58,173,6]	-7	hSpCas9	negative selection	7987819
20637878	20637901	1	-	27260156	NCIH1373	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.24574143161134798	[1062]	[1405,888,1962,375]	2	hSpCas9	negative selection	8052072
20637880	20637903	1	+	27260156	NCIH1373	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.02811854807170988	[43]	[35,32,101,4]	0	hSpCas9	negative selection	8052073
20633542	20633565	1	+	27260156	PATU8902	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.4016883069865247	[142]	[282,30,93,213]	-4	hSpCas9	negative selection	8109070
20637878	20637901	1	-	27260156	PATU8902	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.13466465978128062	[1062]	[1247,1174,1085,2023]	-1	hSpCas9	negative selection	8173323
20637880	20637903	1	+	27260156	PATU8902	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.5231494293671912	[43]	[28,57,5,92]	-5	hSpCas9	negative selection	8173324
20633542	20633565	1	+	27260156	PANC1	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.38691934936427597	[142]	[83,144,37,113]	-6	hSpCas9	negative selection	8230321
20637878	20637901	1	-	27260156	PANC1	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.07843891645401047	[1062]	[648,1458,616,846]	-1	hSpCas9	negative selection	8294574
20637880	20637903	1	+	27260156	PANC1	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.01062614275800522	[43]	[34,40,8,60]	0	hSpCas9	negative selection	8294575
20633542	20633565	1	+	27260156	PANC0813	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.22857248567147748	[142]	[387,193,131,95]	3	hSpCas9	negative selection	8351572
20637878	20637901	1	-	27260156	PANC0813	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.22154527539313773	[1062]	[1086,934,1088,1166]	-4	hSpCas9	negative selection	8415825
20637880	20637903	1	+	27260156	PANC0813	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.9542920304294511	[43]	[104,132,136,29]	9	hSpCas9	negative selection	8415826
20633542	20633565	1	+	27260156	RDES	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.00579370276509894	[142]	[187,156,153,147]	0	hSpCas9	negative selection	8472823
20637878	20637901	1	-	27260156	RDES	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.018656102000833563	[1062]	[1136,1201,1168,1307]	0	hSpCas9	negative selection	8537076
20637880	20637903	1	+	27260156	RDES	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.3589024948144832	[43]	[58,38,82,83]	6	hSpCas9	negative selection	8537077
20633542	20633565	1	+	27260156	PC3	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.7653503069499656	[142]	[73,31,197,71]	-9	hSpCas9	negative selection	8594074
20637878	20637901	1	-	27260156	PC3	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.0629967139571479	[1062]	[696,949,1766,1362]	1	hSpCas9	negative selection	8658327
20637880	20637903	1	+	27260156	PC3	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-1.0666855391612091	[43]	[33,10,17,8]	-9	hSpCas9	negative selection	8658328
20633542	20633565	1	+	27260156	PATU8988T	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.0520786944591185	[142]	[109,68,271,68]	-1	hSpCas9	negative selection	8715325
20637878	20637901	1	-	27260156	PATU8988T	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.042243172029701626	[1062]	[1052,1059,1184,919]	0	hSpCas9	negative selection	8779578
20637880	20637903	1	+	27260156	PATU8988T	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.6941768400251171	[43]	[128,50,35,56]	9	hSpCas9	negative selection	8779579
20633542	20633565	1	+	27260156	T47D	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	-0.4908875038058622	[142]	[110,108,108,146]	-8	hSpCas9	negative selection	8836576
20637878	20637901	1	-	27260156	T47D	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.09830618856827167	[1062]	[1379,1302,1296,1324]	2	hSpCas9	negative selection	8900829
20637880	20637903	1	+	27260156	T47D	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.06780214817586128	[43]	[37,38,71,46]	-1	hSpCas9	negative selection	8900830
20633542	20633565	1	+	27260156	SU8686	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.2328214082610458	[142]	[169,136,179,184]	4	hSpCas9	negative selection	8957827
20637878	20637901	1	-	27260156	SU8686	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.0495253624293146	[1062]	[1029,989,1062,979]	-1	hSpCas9	negative selection	9022080
20637880	20637903	1	+	27260156	SU8686	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	1.437964392779169	[43]	[132,34,210,101]	9	hSpCas9	negative selection	9022081
20633542	20633565	1	+	27260156	SKES1	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.10579211763753449	[142]	[85,201,149,168]	2	hSpCas9	negative selection	9079078
20637878	20637901	1	-	27260156	SKES1	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.09640958655899756	[1062]	[1090,1085,989,833]	-2	hSpCas9	negative selection	9143331
20637880	20637903	1	+	27260156	SKES1	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-1.1078645168441832	[43]	[8,15,33,19]	-9	hSpCas9	negative selection	9143332
20633542	20633565	1	+	27260156	TOV112D	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.14750653113273593	[142]	[99,200,187,150]	3	hSpCas9	negative selection	9200329
20637878	20637901	1	-	27260156	TOV112D	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.01938658859438891	[1062]	[1028,1329,717,1288]	0	hSpCas9	negative selection	9264582
20637880	20637903	1	+	27260156	TOV112D	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	-0.4782494833116848	[43]	[69,38,7,14]	-7	hSpCas9	negative selection	9264583
20633542	20633565	1	+	27260156	TC71	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.24639438339586572	[142]	[244,167,127,186]	6	hSpCas9	negative selection	9321580
20637878	20637901	1	-	27260156	TC71	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	-0.013622407589898522	[1062]	[1142,1097,1075,1203]	0	hSpCas9	negative selection	9385833
20637880	20637903	1	+	27260156	TC71	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.33568170411410225	[43]	[61,33,34,110]	7	hSpCas9	negative selection	9385834
20633542	20633565	1	+	27260156	TC32	viability	CGCCACCATGGCGGTGCGACAGG	PINK1	ENSG00000158828	0.06370390087292743	[142]	[79,193,121,139]	1	hSpCas9	negative selection	9442831
20637878	20637901	1	-	27260156	TC32	viability	TGCAAGCGTCTCGTGTCCAACGG	PINK1	ENSG00000158828	0.11919132921392994	[1062]	[1001,847,1495,1100]	2	hSpCas9	negative selection	9507084
20637880	20637903	1	+	27260156	TC32	viability	GTTGGACACGAGACGCTTGCAGG	PINK1	ENSG00000158828	0.07063615442538973	[43]	[31,30,34,79]	1	hSpCas9	negative selection	9507085
20633830	20633853	1	-	27869803	HPAFII	viability after 27 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	1.969460584982066	[124]	[546,15,NaN]	9	hSpCas9	negative selection	9531856
20638098	20638121	1	-	27869803	HPAFII	viability after 27 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	-0.23982455508809347	[311]	[121,152,NaN]	-2	hSpCas9	negative selection	9531857
20633830	20633853	1	-	27869803	HPAFII	viability after 15 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	0.5415530366244528	[124]	[427,50,NaN]	6	hSpCas9	negative selection	9614305
20638098	20638121	1	-	27869803	HPAFII	viability after 15 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	0.20966891670340404	[311]	[388,386,NaN]	2	hSpCas9	negative selection	9614306
20633830	20633853	1	-	27869803	ASPC1	viability after 36 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	0.05695559342734746	[479]	[467,97,26]	0	hSpCas9	negative selection	9696754
20638098	20638121	1	-	27869803	ASPC1	viability after 36 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	0.5341826567157286	[860]	[342,441,489]	5	hSpCas9	negative selection	9696755
20633830	20633853	1	-	27869803	PATU8988S	viability after 35 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-1.1303995815165244	[401]	[54,92,NaN]	-8	hSpCas9	negative selection	9779203
20638098	20638121	1	-	27869803	PATU8988S	viability after 35 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	0.6083432618012505	[747]	[357,560,NaN]	6	hSpCas9	negative selection	9779204
20633830	20633853	1	-	27869803	PATU8988S	viability after 31 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	-0.3454104751883606	[401]	[152,91,NaN]	-4	hSpCas9	negative selection	9861652
20638098	20638121	1	-	27869803	PATU8988S	viability after 31 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	0.6171684864995786	[747]	[310,643,NaN]	7	hSpCas9	negative selection	9861653
20633830	20633853	1	-	27869803	HPAFII	viability after 35 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	1.9109782677081593	[124]	[427,23,NaN]	9	hSpCas9	negative selection	9944101
20638098	20638121	1	-	27869803	HPAFII	viability after 35 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	-0.043989069503296785	[311]	[92,220,NaN]	0	hSpCas9	negative selection	9944102
20633830	20633853	1	-	27869803	HPAFII	viability after 31 days	GAAAGACTGCCCGGCCGCAAGGG	PINK1	ENSG00000158828	2.0535950050919363	[124]	[541,17,NaN]	9	hSpCas9	negative selection	10026550
20638098	20638121	1	-	27869803	HPAFII	viability after 31 days	CCACATCATCTTGATGGCCAAGG	PINK1	ENSG00000158828	-0.6012637369383799	[311]	[68,165,NaN]	-4	hSpCas9	negative selection	10026551
20633856	20633879	1	-	28162770	P31FUJ	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	-0.7254006869868752	[120]	[85]	-5	hSpCas9	negative selection	10211515
20638043	20638066	1	+	28162770	P31FUJ	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	2.070389327891398	[123]	[611]	9	hSpCas9	negative selection	10211516
20637849	20637872	1	+	28162770	P31FUJ	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	0.25858618099457975	[68]	[96]	2	hSpCas9	negative selection	10211517
20639948	20639971	1	+	28162770	P31FUJ	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	0.21399785724925308	[145]	[198]	2	hSpCas9	negative selection	10211518
20633578	20633601	1	-	28162770	P31FUJ	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	1.2819806472241042	[343]	[982]	9	hSpCas9	negative selection	10211519
20637982	20638005	1	+	28162770	P31FUJ	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	1.064179533342753	[69]	[171]	9	hSpCas9	negative selection	10211520
20637998	20638021	1	+	28162770	P31FUJ	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	-1.269144051478099	[200]	[97]	-7	hSpCas9	negative selection	10211521
20633856	20633879	1	-	28162770	TF1	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10380881
20638043	20638066	1	+	28162770	TF1	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	NaN	[NaN]	[101]	1	hSpCas9	negative selection	10380882
20637849	20637872	1	+	28162770	TF1	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10380883
20639948	20639971	1	+	28162770	TF1	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	NaN	[NaN]	[198]	1	hSpCas9	negative selection	10380884
20633578	20633601	1	-	28162770	TF1	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	NaN	[NaN]	[600]	1	hSpCas9	negative selection	10380885
20637982	20638005	1	+	28162770	TF1	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10380886
20637998	20638021	1	+	28162770	TF1	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	NaN	[NaN]	[166]	1	hSpCas9	negative selection	10380887
20633856	20633879	1	-	28162770	SKM1	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	-0.3195013574928224	[35]	[50]	-3	hSpCas9	negative selection	10550247
20638043	20638066	1	+	28162770	SKM1	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	-0.4500329206350475	[33]	[43]	-4	hSpCas9	negative selection	10550248
20637849	20637872	1	+	28162770	SKM1	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-0.7150864941054935	[25]	[27]	-5	hSpCas9	negative selection	10550249
20639948	20639971	1	+	28162770	SKM1	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	0.1432328838173179	[41]	[81]	1	hSpCas9	negative selection	10550250
20633578	20633601	1	-	28162770	SKM1	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.7398771895861095	[62]	[185]	7	hSpCas9	negative selection	10550251
20637982	20638005	1	+	28162770	SKM1	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	2.005817326595314	[19]	[141]	9	hSpCas9	negative selection	10550252
20637998	20638021	1	+	28162770	SKM1	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	0.5499670793649524	[33]	[87]	5	hSpCas9	negative selection	10550253
20633856	20633879	1	-	28162770	SKM1	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	-0.3195013574928224	[35]	[50]	-3	hSpCas9	negative selection	10719613
20638043	20638066	1	+	28162770	SKM1	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	-0.4500329206350475	[33]	[43]	-4	hSpCas9	negative selection	10719614
20637849	20637872	1	+	28162770	SKM1	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-0.7150864941054935	[25]	[27]	-5	hSpCas9	negative selection	10719615
20639948	20639971	1	+	28162770	SKM1	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	0.1432328838173179	[41]	[81]	1	hSpCas9	negative selection	10719616
20633578	20633601	1	-	28162770	SKM1	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.7398771895861095	[62]	[185]	7	hSpCas9	negative selection	10719617
20637982	20638005	1	+	28162770	SKM1	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	2.005817326595314	[19]	[141]	9	hSpCas9	negative selection	10719618
20637998	20638021	1	+	28162770	SKM1	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	0.5499670793649524	[33]	[87]	5	hSpCas9	negative selection	10719619
20633856	20633879	1	-	28162770	PL21	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	-0.21489788478952376	[135]	[50]	-1	hSpCas9	negative selection	10888979
20638043	20638066	1	+	28162770	PL21	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	-0.9627989566368852	[102]	[22]	-6	hSpCas9	negative selection	10888980
20637849	20637872	1	+	28162770	PL21	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-0.6578413806382519	[86]	[23]	-4	hSpCas9	negative selection	10888981
20639948	20639971	1	+	28162770	PL21	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	-0.012163989223543979	[189]	[81]	0	hSpCas9	negative selection	10888982
20633578	20633601	1	-	28162770	PL21	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.3532563282450784	[258]	[143]	3	hSpCas9	negative selection	10888983
20637982	20638005	1	+	28162770	PL21	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	-0.13689537278825048	[47]	[18]	-1	hSpCas9	negative selection	10888984
20637998	20638021	1	+	28162770	PL21	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	-1.3234223415676927	[91]	[15]	-7	hSpCas9	negative selection	10888985
20633856	20633879	1	-	28162770	P31FUJ	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	-0.7254006869868752	[120]	[85]	-5	hSpCas9	negative selection	11058345
20638043	20638066	1	+	28162770	P31FUJ	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	2.070389327891398	[123]	[611]	9	hSpCas9	negative selection	11058346
20637849	20637872	1	+	28162770	P31FUJ	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	0.25858618099457975	[68]	[96]	2	hSpCas9	negative selection	11058347
20639948	20639971	1	+	28162770	P31FUJ	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	0.21399785724925308	[145]	[198]	2	hSpCas9	negative selection	11058348
20633578	20633601	1	-	28162770	P31FUJ	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	1.2819806472241042	[343]	[982]	9	hSpCas9	negative selection	11058349
20637982	20638005	1	+	28162770	P31FUJ	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	1.064179533342753	[69]	[171]	9	hSpCas9	negative selection	11058350
20637998	20638021	1	+	28162770	P31FUJ	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	-1.269144051478099	[200]	[97]	-7	hSpCas9	negative selection	11058351
20633856	20633879	1	-	28162770	OCIAML5	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	-1.530138475976635	[63]	[39]	-7	hSpCas9	negative selection	11227711
20638043	20638066	1	+	28162770	OCIAML5	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	-1.151626852722905	[63]	[51]	-6	hSpCas9	negative selection	11227712
20637849	20637872	1	+	28162770	OCIAML5	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	0.604791104109474	[50]	[139]	5	hSpCas9	negative selection	11227713
20639948	20639971	1	+	28162770	OCIAML5	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	-0.779658075335947	[135]	[142]	-5	hSpCas9	negative selection	11227714
20633578	20633601	1	-	28162770	OCIAML5	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	1.0986525263647842	[133]	[517]	8	hSpCas9	negative selection	11227715
20637982	20638005	1	+	28162770	OCIAML5	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	0.06547126894402999	[53]	[101]	0	hSpCas9	negative selection	11227716
20637998	20638021	1	+	28162770	OCIAML5	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	-0.8693445622958323	[83]	[82]	-5	hSpCas9	negative selection	11227717
20633856	20633879	1	-	28162770	EOL1	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	0.16245758324871246	[250]	[147]	1	hSpCas9	negative selection	11397077
20638043	20638066	1	+	28162770	EOL1	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	0.5064043614238691	[154]	[115]	4	hSpCas9	negative selection	11397078
20637849	20637872	1	+	28162770	EOL1	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	0.3196857134116734	[145]	[95]	3	hSpCas9	negative selection	11397079
20639948	20639971	1	+	28162770	EOL1	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	0.5690671169721456	[347]	[271]	5	hSpCas9	negative selection	11397080
20633578	20633601	1	-	28162770	EOL1	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	1.2464758664578968	[315]	[394]	9	hSpCas9	negative selection	11397081
20637982	20638005	1	+	28162770	EOL1	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	-0.35229243378828956	[62]	[25]	-3	hSpCas9	negative selection	11397082
20637998	20638021	1	+	28162770	EOL1	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	-0.38956081885752847	[183]	[73]	-3	hSpCas9	negative selection	11397083
20633856	20633879	1	-	28162770	MOLM13	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	0.2614385040771525	[179]	[155]	2	hSpCas9	negative selection	11566443
20638043	20638066	1	+	28162770	MOLM13	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	0.7618805999288183	[145]	[178]	6	hSpCas9	negative selection	11566444
20637849	20637872	1	+	28162770	MOLM13	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	0.8330219749971088	[124]	[160]	6	hSpCas9	negative selection	11566445
20639948	20639971	1	+	28162770	MOLM13	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	0.41990935264275725	[213]	[206]	3	hSpCas9	negative selection	11566446
20633578	20633601	1	-	28162770	MOLM13	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	-0.41067249100544545	[352]	[191]	-2	hSpCas9	negative selection	11566447
20637982	20638005	1	+	28162770	MOLM13	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	0.21205047711498892	[79]	[66]	1	hSpCas9	negative selection	11566448
20637998	20638021	1	+	28162770	MOLM13	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	-0.3577149129678827	[178]	[100]	-2	hSpCas9	negative selection	11566449
20633856	20633879	1	-	28162770	HEL	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	-1.2291048165089609	[182]	[49]	-6	hSpCas9	negative selection	11735809
20638043	20638066	1	+	28162770	HEL	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	-0.002344661158369954	[146]	[93]	0	hSpCas9	negative selection	11735810
20637849	20637872	1	+	28162770	HEL	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	0.9906621354206637	[87]	[111]	8	hSpCas9	negative selection	11735811
20639948	20639971	1	+	28162770	HEL	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	-0.4838946065306603	[237]	[108]	-3	hSpCas9	negative selection	11735812
20633578	20633601	1	-	28162770	HEL	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.28309957138060415	[280]	[218]	2	hSpCas9	negative selection	11735813
20637982	20638005	1	+	28162770	HEL	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	-0.35726116799964314	[103]	[51]	-3	hSpCas9	negative selection	11735814
20637998	20638021	1	+	28162770	HEL	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	-1.3488489281834428	[170]	[42]	-7	hSpCas9	negative selection	11735815
20633856	20633879	1	-	28162770	MV411	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	-0.34209767972820515	[157]	[104]	-3	hSpCas9	negative selection	11905175
20638043	20638066	1	+	28162770	MV411	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	0.39263546632271096	[84]	[93]	3	hSpCas9	negative selection	11905176
20637849	20637872	1	+	28162770	MV411	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-0.20186985058081452	[70]	[51]	-1	hSpCas9	negative selection	11905177
20639948	20639971	1	+	28162770	MV411	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	-0.4682594266297795	[201]	[122]	-3	hSpCas9	negative selection	11905178
20633578	20633601	1	-	28162770	MV411	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	-0.026595854000275754	[236]	[195]	0	hSpCas9	negative selection	11905179
20637982	20638005	1	+	28162770	MV411	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	-0.650682835198011	[81]	[43]	-4	hSpCas9	negative selection	11905180
20637998	20638021	1	+	28162770	MV411	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	-0.5469783155673307	[110]	[63]	-4	hSpCas9	negative selection	11905181
20633856	20633879	1	-	28162770	MONOMAC1	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	-1.0997396457046387	[85]	[45]	-7	hSpCas9	negative selection	12074541
20638043	20638066	1	+	28162770	MONOMAC1	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	-1.2208835890139214	[60]	[29]	-7	hSpCas9	negative selection	12074542
20637849	20637872	1	+	28162770	MONOMAC1	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	0.04397125244424127	[54]	[64]	0	hSpCas9	negative selection	12074543
20639948	20639971	1	+	28162770	MONOMAC1	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	0.2272191822486688	[116]	[156]	2	hSpCas9	negative selection	12074544
20633578	20633601	1	-	28162770	MONOMAC1	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.5466233996806606	[128]	[215]	5	hSpCas9	negative selection	12074545
20637982	20638005	1	+	28162770	MONOMAC1	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	1.145355350387524	[27]	[70]	8	hSpCas9	negative selection	12074546
20637998	20638021	1	+	28162770	MONOMAC1	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	-0.24434256183791025	[61]	[59]	-2	hSpCas9	negative selection	12074547
20633856	20633879	1	-	28162770	OCIAML2	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	0.24881800766601536	[28]	[190]	2	hSpCas9	negative selection	12243907
20638043	20638066	1	+	28162770	OCIAML2	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	0.294904921120816	[14]	[101]	3	hSpCas9	negative selection	12243908
20637849	20637872	1	+	28162770	OCIAML2	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-0.14870173035479883	[10]	[54]	-1	hSpCas9	negative selection	12243909
20639948	20639971	1	+	28162770	OCIAML2	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	-0.5820511079105842	[36]	[136]	-4	hSpCas9	negative selection	12243910
20633578	20633601	1	-	28162770	OCIAML2	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.5467174183217357	[30]	[250]	5	hSpCas9	negative selection	12243911
20637982	20638005	1	+	28162770	OCIAML2	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	0.16495874854896275	[13]	[86]	1	hSpCas9	negative selection	12243912
20637998	20638021	1	+	28162770	OCIAML2	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	-0.7264687296717511	[19]	[66]	-5	hSpCas9	negative selection	12243913
20633856	20633879	1	-	28162770	OCIAML3	viability	GAGGCCCAGCCCTAGCCCGAAGG	PINK1	ENSG00000158828	-1.1140146992045494	[37]	[52]	-7	hSpCas9	negative selection	12413273
20638043	20638066	1	+	28162770	OCIAML3	viability	GGTACCAGTGCACCAGGAGAAGG	PINK1	ENSG00000158828	0.5274558721615042	[36]	[160]	5	hSpCas9	negative selection	12413274
20637849	20637872	1	+	28162770	OCIAML3	viability	TTACCCAGAAAAGCAAGCCGGGG	PINK1	ENSG00000158828	-0.7575063726070428	[13]	[24]	-5	hSpCas9	negative selection	12413275
20639948	20639971	1	+	28162770	OCIAML3	viability	GAGCCGAGTGGCCTTGGCTGGGG	PINK1	ENSG00000158828	0.4154526889249033	[37]	[152]	4	hSpCas9	negative selection	12413276
20633578	20633601	1	-	28162770	OCIAML3	viability	GCAGCGCTCGACCCAGCTGCAGG	PINK1	ENSG00000158828	0.8080908032471824	[48]	[258]	7	hSpCas9	negative selection	12413277
20637982	20638005	1	+	28162770	OCIAML3	viability	TACATTGCCCCAGAACCTGGAGG	PINK1	ENSG00000158828	-0.17079620959961916	[21]	[58]	-1	hSpCas9	negative selection	12413278
20637998	20638021	1	+	28162770	OCIAML3	viability	CTGGAGGTGACAAAGAGCACCGG	PINK1	ENSG00000158828	-0.8055117455178751	[43]	[75]	-5	hSpCas9	negative selection	12413279