Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 57104
• Symbol: PNPLA2
• Description: patatin like domain 2, triacylglycerol lipase

DataSource: http://genomecrispr.dkfz.de/#!/results/PNPLA2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
821722	821745	11	-	26472758	Jiyoye	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.8841406299279192	[170]	[237]	6	hSpCas9	negative selection	123118
821981	822004	11	-	26472758	Jiyoye	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	-0.5263972567551507	[190]	[99]	-4	hSpCas9	negative selection	123119
822555	822578	11	-	26472758	Jiyoye	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	1.1441409756720797	[8]	[14]	7	hSpCas9	negative selection	123120
822592	822615	11	-	26472758	Jiyoye	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	1.374753903813496	[44]	[87]	8	hSpCas9	negative selection	123121
819808	819831	11	+	26472758	Jiyoye	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	0.39795685147649473	[156]	[155]	3	hSpCas9	negative selection	123122
819818	819841	11	-	26472758	Jiyoye	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	-0.13514278180678901	[149]	[102]	-1	hSpCas9	negative selection	123123
819831	819854	11	-	26472758	Jiyoye	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	0.6587141485018377	[41]	[49]	5	hSpCas9	negative selection	123124
821952	821975	11	+	26472758	Jiyoye	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	0.006295945223688981	[168]	[127]	0	hSpCas9	negative selection	123125
821722	821745	11	-	26472758	KBM7	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	-0.1027028727066912	[889,655]	[421,256]	-1	hSpCas9	negative selection	314236
821981	822004	11	-	26472758	KBM7	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	0.6551756753479954	[645,751]	[455,584]	7	hSpCas9	negative selection	314237
822555	822578	11	-	26472758	KBM7	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	-0.01510864213427121	[93,74]	[37,39]	0	hSpCas9	negative selection	314238
822592	822615	11	-	26472758	KBM7	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	0.5716639877245848	[342,136]	[157,163]	6	hSpCas9	negative selection	314239
819808	819831	11	+	26472758	KBM7	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	-0.24945600597002948	[661,522]	[200,260]	-2	hSpCas9	negative selection	314240
819818	819841	11	-	26472758	KBM7	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	-0.05681956138670646	[598,737]	[299,312]	0	hSpCas9	negative selection	314241
819831	819854	11	-	26472758	KBM7	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	0.22425180072256018	[449,319]	[107,298]	2	hSpCas9	negative selection	314242
821952	821975	11	+	26472758	KBM7	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	1.1632660646488222	[688,573]	[1019,341]	9	hSpCas9	negative selection	314243
821722	821745	11	-	26472758	Raji	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.42017097640449297	[379]	[117]	4	hSpCas9	negative selection	505354
821981	822004	11	-	26472758	Raji	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	0.28823218585214844	[306]	[86]	2	hSpCas9	negative selection	505355
822555	822578	11	-	26472758	Raji	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	-0.725506478791142	[56]	[7]	-5	hSpCas9	negative selection	505356
822592	822615	11	-	26472758	Raji	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	1.1496117707628968	[100]	[51]	8	hSpCas9	negative selection	505357
819808	819831	11	+	26472758	Raji	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	0.5430313143277292	[277]	[93]	5	hSpCas9	negative selection	505358
819818	819841	11	-	26472758	Raji	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	-0.1640794925307752	[308]	[63]	-1	hSpCas9	negative selection	505359
819831	819854	11	-	26472758	Raji	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	0.07990279895149244	[158]	[38]	0	hSpCas9	negative selection	505360
821952	821975	11	+	26472758	Raji	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	0.17192378756831012	[305]	[79]	1	hSpCas9	negative selection	505361
821722	821745	11	-	26472758	K562	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.2959490283065289	[769]	[797]	2	hSpCas9	negative selection	696472
821981	822004	11	-	26472758	K562	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	-0.40803479927738145	[546]	[347]	-3	hSpCas9	negative selection	696473
822555	822578	11	-	26472758	K562	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	0.9309192548496652	[63]	[102]	7	hSpCas9	negative selection	696474
822592	822615	11	-	26472758	K562	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	0.5996840064279216	[153]	[196]	5	hSpCas9	negative selection	696475
819808	819831	11	+	26472758	K562	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	0.26532771742942746	[410]	[416]	2	hSpCas9	negative selection	696476
819818	819841	11	-	26472758	K562	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	0.4128830678106662	[548]	[616]	3	hSpCas9	negative selection	696477
819831	819854	11	-	26472758	K562	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	0.6914463411897276	[222]	[303]	5	hSpCas9	negative selection	696478
821952	821975	11	+	26472758	K562	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	-0.33228967184205294	[609]	[408]	-2	hSpCas9	negative selection	696479
819769	819792	11	-	26627737	DLD1	viability	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	-1.6628636912238228	[470]	[33,0,94]	-8	hSpCas9	negative selection	781289
821796	821819	11	-	26627737	DLD1	viability	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-1.9103019923685658	[517]	[51,28,46]	-8	hSpCas9	negative selection	781290
822467	822490	11	-	26627737	DLD1	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-1.393628964219971	[332]	[1,57,56]	-8	hSpCas9	negative selection	781291
823565	823588	11	-	26627737	DLD1	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.10676226693007959	[473]	[80,77,235]	-1	hSpCas9	negative selection	781292
819769	819792	11	-	26627737	GBM cells	viability after 5 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.035376117434957444	[251]	[172,103]	0	hSpCas9	negative selection	863604
821796	821819	11	-	26627737	GBM cells	viability after 5 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.16089552034961796	[196]	[72,115]	-2	hSpCas9	negative selection	863605
822467	822490	11	-	26627737	GBM cells	viability after 5 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.751501687324087	[123]	[46,31]	-8	hSpCas9	negative selection	863606
823565	823588	11	-	26627737	GBM cells	viability after 5 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.3965420086404857	[242]	[116,80]	-6	hSpCas9	negative selection	863607
819769	819792	11	-	26627737	GBM cells	viability after 13 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.03894748009299673	[251]	[113,161]	0	hSpCas9	negative selection	945919
821796	821819	11	-	26627737	GBM cells	viability after 13 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.3228407978038583	[196]	[101,71]	-4	hSpCas9	negative selection	945920
822467	822490	11	-	26627737	GBM cells	viability after 13 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.5568571630408021	[123]	[69,25]	-6	hSpCas9	negative selection	945921
823565	823588	11	-	26627737	GBM cells	viability after 13 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.5986689166634133	[242]	[80,91]	-6	hSpCas9	negative selection	945922
819769	819792	11	-	26627737	GBM cells	viability after 21 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.9426645025905983	[251]	[294,233]	8	hSpCas9	negative selection	1028234
821796	821819	11	-	26627737	GBM cells	viability after 21 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	0.17598449688945805	[196]	[122,118]	1	hSpCas9	negative selection	1028235
822467	822490	11	-	26627737	GBM cells	viability after 21 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.21819473853275695	[123]	[59,55]	-2	hSpCas9	negative selection	1028236
823565	823588	11	-	26627737	GBM cells	viability after 21 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.1528629968555172	[242]	[112,123]	-1	hSpCas9	negative selection	1028237
819769	819792	11	-	26627737	RPE1	viability after 9 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	-0.07303846855568241	[512]	[208,79]	0	hSpCas9	negative selection	1110549
821796	821819	11	-	26627737	RPE1	viability after 9 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.471631402413878	[809]	[119,263]	-3	hSpCas9	negative selection	1110550
822467	822490	11	-	26627737	RPE1	viability after 9 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-1.0940686405686695	[273]	[37,42]	-7	hSpCas9	negative selection	1110551
823565	823588	11	-	26627737	RPE1	viability after 9 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.4090520878978878	[742]	[110,257]	-3	hSpCas9	negative selection	1110552
819769	819792	11	-	26627737	RPE1	viability after 12 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.6336072223619015	[512]	[241,183]	4	hSpCas9	negative selection	1192864
821796	821819	11	-	26627737	RPE1	viability after 12 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.6381513169644261	[809]	[116,163]	-4	hSpCas9	negative selection	1192865
822467	822490	11	-	26627737	RPE1	viability after 12 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-1.907037399414255	[273]	[23,14]	-8	hSpCas9	negative selection	1192866
823565	823588	11	-	26627737	RPE1	viability after 12 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-1.2845606971085202	[742]	[96,65]	-7	hSpCas9	negative selection	1192867
819769	819792	11	-	26627737	RPE1	viability after 15 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	1.1067193499185146	[512]	[395,231]	6	hSpCas9	negative selection	1275179
821796	821819	11	-	26627737	RPE1	viability after 15 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.9487541096406912	[809]	[106,129]	-5	hSpCas9	negative selection	1275180
822467	822490	11	-	26627737	RPE1	viability after 15 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-1.1493335179650639	[273]	[9,58]	-6	hSpCas9	negative selection	1275181
823565	823588	11	-	26627737	RPE1	viability after 15 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.44016662376308446	[742]	[187,122]	-3	hSpCas9	negative selection	1275182
819769	819792	11	-	26627737	RPE1	viability after 18 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.5901172054960722	[512]	[161,257]	3	hSpCas9	negative selection	1357494
821796	821819	11	-	26627737	RPE1	viability after 18 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.37309267496341647	[809]	[176,159]	-2	hSpCas9	negative selection	1357495
822467	822490	11	-	26627737	RPE1	viability after 18 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-1.7642419433460252	[273]	[14,28]	-8	hSpCas9	negative selection	1357496
823565	823588	11	-	26627737	RPE1	viability after 18 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.7761338938101656	[742]	[104,129]	-5	hSpCas9	negative selection	1357497
819769	819792	11	-	26627737	HeLa	viability after 8 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.39183515628556886	[396]	[119,183,343]	3	hSpCas9	negative selection	1439809
821796	821819	11	-	26627737	HeLa	viability after 8 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	0.36074047994224245	[396]	[256,294,127]	3	hSpCas9	negative selection	1439810
822467	822490	11	-	26627737	HeLa	viability after 8 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.7746985397308259	[276]	[91,66,57]	-7	hSpCas9	negative selection	1439811
823565	823588	11	-	26627737	HeLa	viability after 8 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.15583231217342486	[304]	[221,82,77]	-1	hSpCas9	negative selection	1439812
819769	819792	11	-	26627737	HeLa	viability after 12 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.38114752667916046	[396]	[319,110,223]	3	hSpCas9	negative selection	1522124
821796	821819	11	-	26627737	HeLa	viability after 12 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.9372601537780274	[396]	[167,51,42]	-7	hSpCas9	negative selection	1522125
822467	822490	11	-	26627737	HeLa	viability after 12 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-2.6170965305652674	[276]	[27,20,6]	-9	hSpCas9	negative selection	1522126
823565	823588	11	-	26627737	HeLa	viability after 12 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.9367960778542479	[304]	[327,225,173]	7	hSpCas9	negative selection	1522127
819769	819792	11	-	26627737	HeLa	viability after 15 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.8363681684105196	[396]	[472,238,139]	6	hSpCas9	negative selection	1604439
821796	821819	11	-	26627737	HeLa	viability after 15 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.7686569745721681	[396]	[87,97,98]	-6	hSpCas9	negative selection	1604440
822467	822490	11	-	26627737	HeLa	viability after 15 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-1.5378001671222463	[276]	[86,24,0]	-8	hSpCas9	negative selection	1604441
823565	823588	11	-	26627737	HeLa	viability after 15 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.0893666865100074	[304]	[149,138,104]	0	hSpCas9	negative selection	1604442
819769	819792	11	-	26627737	HeLa	viability after 18 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.8320278721632851	[396]	[317,194,139]	6	hSpCas9	negative selection	1686754
821796	821819	11	-	26627737	HeLa	viability after 18 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.7267580059987974	[396]	[58,87,98]	-6	hSpCas9	negative selection	1686755
822467	822490	11	-	26627737	HeLa	viability after 18 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-1.3983769556275176	[276]	[64,21,0]	-8	hSpCas9	negative selection	1686756
823565	823588	11	-	26627737	HeLa	viability after 18 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.15241472878956205	[304]	[108,118,104]	1	hSpCas9	negative selection	1686757
819769	819792	11	-	26627737	HCT116	viability after 6 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.10825658287415335	[494]	[128,58]	0	hSpCas9	negative selection	1769069
821796	821819	11	-	26627737	HCT116	viability after 6 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.8986498988044254	[683]	[125,19]	-5	hSpCas9	negative selection	1769070
822467	822490	11	-	26627737	HCT116	viability after 6 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-1.25177650202837	[339]	[15,25]	-6	hSpCas9	negative selection	1769071
823565	823588	11	-	26627737	HCT116	viability after 6 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	1.1793518629105992	[315]	[136,98]	6	hSpCas9	negative selection	1769072
819769	819792	11	-	26627737	HCT116	viability after 8 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.6797496664939954	[126]	[80,163,90]	6	hSpCas9	negative selection	1851384
821796	821819	11	-	26627737	HCT116	viability after 8 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.2857237460190343	[402]	[234,93,217]	-3	hSpCas9	negative selection	1851385
822467	822490	11	-	26627737	HCT116	viability after 8 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	1.2576284842839744	[47]	[68,71,48]	8	hSpCas9	negative selection	1851386
823565	823588	11	-	26627737	HCT116	viability after 8 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.580722018248583	[163]	[128,111,163]	6	hSpCas9	negative selection	1851387
819769	819792	11	-	26627737	HCT116	viability after 9 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	-0.5415027515763304	[494]	[187,13]	-4	hSpCas9	negative selection	1933699
821796	821819	11	-	26627737	HCT116	viability after 9 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	0.48764491233463114	[683]	[321,203]	3	hSpCas9	negative selection	1933700
822467	822490	11	-	26627737	HCT116	viability after 9 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-1.0131257998042464	[339]	[68,25]	-6	hSpCas9	negative selection	1933701
823565	823588	11	-	26627737	HCT116	viability after 9 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.9215115860146861	[315]	[151,165]	6	hSpCas9	negative selection	1933702
819769	819792	11	-	26627737	HCT116	viability after 12 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.8734498858940808	[126]	[148,143,71]	7	hSpCas9	negative selection	2016014
821796	821819	11	-	26627737	HCT116	viability after 12 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.9116452692510846	[402]	[121,115,98]	-7	hSpCas9	negative selection	2016015
822467	822490	11	-	26627737	HCT116	viability after 12 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	2.273591355297494	[47]	[180,91,86]	9	hSpCas9	negative selection	2016016
823565	823588	11	-	26627737	HCT116	viability after 12 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.6160718208448667	[163]	[93,146,158]	6	hSpCas9	negative selection	2016017
819769	819792	11	-	26627737	HCT116	viability after 15 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	1.559774256227455	[126]	[288,227,137]	9	hSpCas9	negative selection	2098329
821796	821819	11	-	26627737	HCT116	viability after 15 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.7235123851877219	[402]	[149,156,114]	-6	hSpCas9	negative selection	2098330
822467	822490	11	-	26627737	HCT116	viability after 15 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	1.9683539460165371	[47]	[188,78,65]	9	hSpCas9	negative selection	2098331
823565	823588	11	-	26627737	HCT116	viability after 15 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.8206464342034793	[163]	[189,234,77]	7	hSpCas9	negative selection	2098332
819769	819792	11	-	26627737	HCT116	viability after 18 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	1.2967311730391828	[126]	[166,199,78]	8	hSpCas9	negative selection	2180644
821796	821819	11	-	26627737	HCT116	viability after 18 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.023564471730820324	[402]	[193,130,256]	0	hSpCas9	negative selection	2180645
822467	822490	11	-	26627737	HCT116	viability after 18 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	1.9497618984150524	[47]	[113,61,94]	9	hSpCas9	negative selection	2180646
823565	823588	11	-	26627737	HCT116	viability after 18 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.4688218965083067	[163]	[97,158,66]	4	hSpCas9	negative selection	2180647
822897	822920	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCTGCCTCCAAG	PNPLA2	ENSG00000177666	-2.007733074360467	[162,472]	[3,30]	-9	dCas9-VP64	positive selection	2423912
822897	822920	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCTGCCTCCAAG	PNPLA2	ENSG00000177666	2.233334387673139	[58,128]	[217,75]	8	dCas9-VP64	positive selection	2519167
821755	821778	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAGCCATGAGCATGCCAGTGGG	PNPLA2	ENSG00000177666	0.08290161959098044	[3,3]	[3,2]	1	hSpCas9	positive selection	3012269
821797	821820	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.14509738380006104	[3,3]	[4,0]	-2	hSpCas9	positive selection	3012270
819876	819899	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACCCCGGTGACCAGCGCCGTGG	PNPLA2	ENSG00000177666	-0.4520563084180839	[2,2]	[0,1]	-6	hSpCas9	positive selection	3012271
821722	821745	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.11275848763204693	[2,1]	[1,2]	2	hSpCas9	positive selection	3012272
821755	821778	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAGCCATGAGCATGCCAGTGGG	PNPLA2	ENSG00000177666	0.47822175776985376	[3,3]	[4,2]	7	hSpCas9	positive selection	3080127
821797	821820	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.054660438241180734	[3,3]	[3,0]	-1	hSpCas9	positive selection	3080128
819876	819899	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACCCCGGTGACCAGCGCCGTGG	PNPLA2	ENSG00000177666	0.06872338083125845	[2,2]	[2,0]	1	hSpCas9	positive selection	3080129
821722	821745	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.3293319170737561	[2,2]	[1,3]	6	hSpCas9	positive selection	3080130
821719	821742		+	24336571	A375	resistance to PLX after 7 days	CATCCGCAGTTTCCTGCTGAAGG	PNPLA2	ENSG00000177666	-0.2530819627234563	[19,18]	[16,14]	-7	hSpCas9	positive selection	3136558
821797	821820		-	24336571	A375	resistance to PLX after 7 days	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.23550600904964175	[15,13]	[15,17]	7	hSpCas9	positive selection	3136559
822388	822411		+	24336571	A375	resistance to PLX after 7 days	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.5362925905945144	[14,12]	[21,17]	9	hSpCas9	positive selection	3136560
822516	822539		-	24336571	A375	resistance to PLX after 7 days	TGTTGGTGACCCGCAGCTCGTGG	PNPLA2	ENSG00000177666	0.3254801023885814	[4,3]	[5,4]	8	hSpCas9	positive selection	3136561
821719	821742		+	24336571	A375	resistance to PLX after 14 days	CATCCGCAGTTTCCTGCTGAAGG	PNPLA2	ENSG00000177666	0.12433956484267494	[16,14]	[8,6]	1	hSpCas9	positive selection	3194351
821797	821820		-	24336571	A375	resistance to PLX after 14 days	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	1.09536697665441	[17,8]	[14,11]	8	hSpCas9	positive selection	3194352
822388	822411		+	24336571	A375	resistance to PLX after 14 days	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.02415348366369313	[9,16]	[4,6]	0	hSpCas9	positive selection	3194353
822516	822539		-	24336571	A375	resistance to PLX after 14 days	TGTTGGTGACCCGCAGCTCGTGG	PNPLA2	ENSG00000177666	0.180853278159125	[4,3]	[1,1]	2	hSpCas9	positive selection	3194354
821719	821742		+	24336571	A375	viability after 7 days	CATCCGCAGTTTCCTGCTGAAGG	PNPLA2	ENSG00000177666	0.19464068389357753	[17]	[19,18]	3	hSpCas9	negative selection	3252144
821797	821820		-	24336571	A375	viability after 7 days	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.08236842543430106	[15]	[15,13]	-1	hSpCas9	negative selection	3252145
822388	822411		+	24336571	A375	viability after 7 days	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	-0.2004236849388504	[16]	[14,12]	-3	hSpCas9	negative selection	3252146
822516	822539		-	24336571	A375	viability after 7 days	TGTTGGTGACCCGCAGCTCGTGG	PNPLA2	ENSG00000177666	-0.6859398158164095	[7]	[4,3]	-7	hSpCas9	negative selection	3252147
821719	821742		+	24336571	A375	viability after 14 days	CATCCGCAGTTTCCTGCTGAAGG	PNPLA2	ENSG00000177666	-0.02411120627415797	[17]	[16,14]	0	hSpCas9	negative selection	3309937
821797	821820		-	24336571	A375	viability after 14 days	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.16464262013741598	[15]	[17,8]	-2	hSpCas9	negative selection	3309938
822388	822411		+	24336571	A375	viability after 14 days	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	-0.2092635221232647	[16]	[9,16]	-2	hSpCas9	negative selection	3309939
822516	822539		-	24336571	A375	viability after 14 days	TGTTGGTGACCCGCAGCTCGTGG	PNPLA2	ENSG00000177666	-0.6103215377810473	[7]	[4,3]	-6	hSpCas9	negative selection	3309940
821789	821812	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.5849008694743394	[101,101]	[0,0]	3	hSpCas9	positive selection	3386563
823565	823588	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	1.7027373597681978	[46,46]	[0,0]	7	hSpCas9	positive selection	3386564
823529	823552	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	0.8650087886670746	[83,83]	[0,0]	4	hSpCas9	positive selection	3386565
821754	821777	11	+	26780180	HT29	viability (Avana library 4 designs)	ATAGCCATGAGCATGCCAGTGGG	PNPLA2	ENSG00000177666	0.665152353890477	[]	[]	2	hSpCas9	negative selection	3450378
821797	821820	11	-	26780180	HT29	viability (Avana library 4 designs)	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	1.02227375113727	[]	[]	4	hSpCas9	negative selection	3450379
819876	819899	11	-	26780180	HT29	viability (Avana library 4 designs)	GACCCCGGTGACCAGCGCCGTGG	PNPLA2	ENSG00000177666	3.11079861866107	[]	[]	8	hSpCas9	negative selection	3450380
821722	821745	11	-	26780180	HT29	viability (Avana library 4 designs)	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	1.64203775169111	[]	[]	6	hSpCas9	negative selection	3450381
821754	821777	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGCCATGAGCATGCCAGTGGG	PNPLA2	ENSG00000177666	2.51063855095815	[]	[]	4	hSpCas9	negative selection	3545591
819876	819899	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACCCCGGTGACCAGCGCCGTGG	PNPLA2	ENSG00000177666	-1.96621053682012	[]	[]	-2	hSpCas9	negative selection	3545592
821797	821820	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	3.63985517376508	[]	[]	6	hSpCas9	negative selection	3545593
821722	821745	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	1.56654193294942	[]	[]	2	hSpCas9	negative selection	3545594
821747	821770	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATGCTCATGGCTATCAGCAGG	PNPLA2	ENSG00000177666	-6.13566222629077	[]	[]	-6	hSpCas9	negative selection	3545595
821981	822004	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	-1.15800959052971	[]	[]	-1	hSpCas9	negative selection	3545596
821754	821777	11	+	26780180	A375	viability (Avana lentiGuide)	ATAGCCATGAGCATGCCAGTGGG	PNPLA2	ENSG00000177666	0.693122966658462	[]	[]	0	hSpCas9	negative selection	3654250
819876	819899	11	-	26780180	A375	viability (Avana lentiGuide)	GACCCCGGTGACCAGCGCCGTGG	PNPLA2	ENSG00000177666	8.465430736927	[]	[]	6	hSpCas9	negative selection	3654251
821797	821820	11	-	26780180	A375	viability (Avana lentiGuide)	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.870775656034352	[]	[]	-1	hSpCas9	negative selection	3654252
821722	821745	11	-	26780180	A375	viability (Avana lentiGuide)	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	4.35819086450083	[]	[]	4	hSpCas9	negative selection	3654253
821747	821770	11	-	26780180	A375	viability (Avana lentiGuide)	GCATGCTCATGGCTATCAGCAGG	PNPLA2	ENSG00000177666	18.1658001023316	[]	[]	8	hSpCas9	negative selection	3654254
821981	822004	11	-	26780180	A375	viability (Avana lentiGuide)	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	6.37605679423614	[]	[]	5	hSpCas9	negative selection	3654255
821754	821777	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGCCATGAGCATGCCAGTGGG	PNPLA2	ENSG00000177666	-0.08660377447434442	[5]	[5,4]	-1	hSpCas9	positive selection	3762909
819876	819899	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACCCCGGTGACCAGCGCCGTGG	PNPLA2	ENSG00000177666	-0.10137201703362703	[4]	[4,3]	-2	hSpCas9	positive selection	3762910
821797	821820	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.16639934826757402	[4]	[5,4]	4	hSpCas9	positive selection	3762911
821722	821745	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	-0.638270039080137	[4]	[2,1]	-7	hSpCas9	positive selection	3762912
821747	821770	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATGCTCATGGCTATCAGCAGG	PNPLA2	ENSG00000177666	-0.4040649157173847	[4]	[2,3]	-5	hSpCas9	positive selection	3762913
821981	822004	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	0.035879161468353404	[4]	[4,4]	0	hSpCas9	positive selection	3762914
821754	821777	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGCCATGAGCATGCCAGTGGG	PNPLA2	ENSG00000177666	-0.13016156797013376	[5]	[3,4]	-2	hSpCas9	positive selection	3871516
819876	819899	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACCCCGGTGACCAGCGCCGTGG	PNPLA2	ENSG00000177666	-0.3954501360400917	[4]	[2,3]	-5	hSpCas9	positive selection	3871517
821797	821820	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.41745838144366787	[5]	[0,5]	-5	hSpCas9	positive selection	3871518
821722	821745	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	-0.8252437582105883	[3]	[0,2]	-8	hSpCas9	positive selection	3871519
821747	821770	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATGCTCATGGCTATCAGCAGG	PNPLA2	ENSG00000177666	-0.24442951320804795	[5]	[4,3]	-3	hSpCas9	positive selection	3871520
821981	822004	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	-0.2996246425116014	[4]	[2,3]	-4	hSpCas9	positive selection	3871521
821797	821820	11	-	26780180	A375	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.55606724728421	[]	[]	1	hSpCas9	negative selection	3982349
822388	822411	11	+	26780180	A375	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	1.16641517414542	[]	[]	6	hSpCas9	negative selection	3982350
823565	823588	11	-	26780180	A375	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	1.25263663283844	[]	[]	6	hSpCas9	negative selection	3982351
822467	822490	11	-	26780180	A375	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.838786786129743	[]	[]	3	hSpCas9	negative selection	3982352
823529	823552	11	+	26780180	A375	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	0.731712085599442	[]	[]	2	hSpCas9	negative selection	3982353
821789	821812	11	+	26780180	A375	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	1.22562500762801	[]	[]	6	hSpCas9	negative selection	3982354
821797	821820	11	-	26780180	HT29	viability (GeCKOv2 library)	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.14617978912372	[]	[]	-4	hSpCas9	negative selection	4090315
822388	822411	11	+	26780180	HT29	viability (GeCKOv2 library)	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.592662143647532	[]	[]	2	hSpCas9	negative selection	4090316
823565	823588	11	-	26780180	HT29	viability (GeCKOv2 library)	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	1.81072854753243	[]	[]	8	hSpCas9	negative selection	4090317
822467	822490	11	-	26780180	HT29	viability (GeCKOv2 library)	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.569969374010438	[]	[]	2	hSpCas9	negative selection	4090318
823529	823552	11	+	26780180	HT29	viability (GeCKOv2 library)	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	1.31028734296944	[]	[]	6	hSpCas9	negative selection	4090319
821789	821812	11	+	26780180	HT29	viability (GeCKOv2 library)	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.45672756959534	[]	[]	1	hSpCas9	negative selection	4090320
821719	821742	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATCCGCAGTTTCCTGCTGAAGG	PNPLA2	ENSG00000177666	-0.04962216055207058	[4]	[2,2]	-1	hSpCas9	positive selection	4161593
821797	821820	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.16680147318778848	[4]	[2,3]	4	hSpCas9	positive selection	4161594
822388	822411	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	-0.3181720951331619	[4]	[1,2]	-7	hSpCas9	positive selection	4161595
822516	822539	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTTGGTGACCCGCAGCTCGTGG	PNPLA2	ENSG00000177666	-0.08735773613840947	[1]	[1,0]	-2	hSpCas9	positive selection	4161596
821719	821742	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATCCGCAGTTTCCTGCTGAAGG	PNPLA2	ENSG00000177666	1.403237042650329	[3]	[3,3,3,4]	9	hSpCas9	positive selection	4225615
821797	821820	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.03517620929937873	[4]	[1,3,3,0]	0	hSpCas9	positive selection	4225616
822388	822411	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.05748227358073266	[2]	[0,2,1,0]	0	hSpCas9	positive selection	4225617
822516	822539	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTTGGTGACCCGCAGCTCGTGG	PNPLA2	ENSG00000177666	-0.30817481809976377	[3]	[0,3,0,0]	-4	hSpCas9	positive selection	4225618
821797	821820	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.49860667227950445	[4]	[4,5]	8	hSpCas9	positive selection	4291057
822467	822490	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.09481990462292988	[1]	[0,0]	-2	hSpCas9	positive selection	4291058
822388	822411	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	-0.29126987051238584	[1]	[1,0]	-6	hSpCas9	positive selection	4291059
821789	821812	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	-0.4763989224866321	[2]	[2,0]	-8	hSpCas9	positive selection	4355306
823565	823588	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.13286667447178974	[1]	[0,1]	-3	hSpCas9	positive selection	4355307
823529	823552	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	0.1576968028104418	[1]	[1,1]	3	hSpCas9	positive selection	4355308
819839	819861	11	+	27760321	OCIAML3	viability	ACGCACATCTACGGCGCCTCGG	PNPLA2	ENSG00000177666	0.3315364565698915	[1236,988]	[1015,1183]	4	hSpCas9	negative selection	4429009
821797	821819	11	-	27760321	OCIAML3	viability	ATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.3017642274775827	[1126,1049]	[922,1214]	3	hSpCas9	negative selection	4429010
822385	822407	11	+	27760321	OCIAML3	viability	GTCCCGTGGAAGCGCTACGTGG	PNPLA2	ENSG00000177666	1.1215330451592718	[668,599]	[932,1267]	9	hSpCas9	negative selection	4429011
822466	822488	11	-	27760321	OCIAML3	viability	TGTCACTCTCGCCCGAGAAGGG	PNPLA2	ENSG00000177666	-0.4555854712785068	[353,304]	[156,226]	-5	hSpCas9	negative selection	4429012
823567	823589	11	+	27760321	OCIAML3	viability	TGCGCTTTCTGCAGCGGAACGG	PNPLA2	ENSG00000177666	0.26620369429234614	[548,420]	[282,673]	3	hSpCas9	negative selection	4429013
819839	819861	11	+	27760321	OCIAML2	viability	ACGCACATCTACGGCGCCTCGG	PNPLA2	ENSG00000177666	0.020666020257788853	[1236,988]	[718,1156]	0	hSpCas9	negative selection	4512472
821797	821819	11	-	27760321	OCIAML2	viability	ATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.11335528657655103	[1126,1049]	[863,1069]	1	hSpCas9	negative selection	4512473
822385	822407	11	+	27760321	OCIAML2	viability	GTCCCGTGGAAGCGCTACGTGG	PNPLA2	ENSG00000177666	0.3862677468178537	[668,599]	[616,739]	5	hSpCas9	negative selection	4512474
822466	822488	11	-	27760321	OCIAML2	viability	TGTCACTCTCGCCCGAGAAGGG	PNPLA2	ENSG00000177666	0.22990962332561765	[353,304]	[268,367]	3	hSpCas9	negative selection	4512475
823567	823589	11	+	27760321	OCIAML2	viability	TGCGCTTTCTGCAGCGGAACGG	PNPLA2	ENSG00000177666	0.5206313308561015	[548,420]	[407,756]	7	hSpCas9	negative selection	4512476
819839	819861	11	+	27760321	MV411	viability	ACGCACATCTACGGCGCCTCGG	PNPLA2	ENSG00000177666	0.13167021075082785	[1236,988]	[486,1269]	0	hSpCas9	negative selection	4595935
821797	821819	11	-	27760321	MV411	viability	ATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.4149656243262607	[1126,1049]	[1262,499]	3	hSpCas9	negative selection	4595936
822385	822407	11	+	27760321	MV411	viability	GTCCCGTGGAAGCGCTACGTGG	PNPLA2	ENSG00000177666	1.5063063341629825	[668,599]	[787,1788]	9	hSpCas9	negative selection	4595937
822466	822488	11	-	27760321	MV411	viability	TGTCACTCTCGCCCGAGAAGGG	PNPLA2	ENSG00000177666	-0.219642471112364	[353,304]	[190,178]	-1	hSpCas9	negative selection	4595938
823567	823589	11	+	27760321	MV411	viability	TGCGCTTTCTGCAGCGGAACGG	PNPLA2	ENSG00000177666	0.2976071572138982	[548,420]	[399,375]	2	hSpCas9	negative selection	4595939
819839	819861	11	+	27760321	HL60	viability	ACGCACATCTACGGCGCCTCGG	PNPLA2	ENSG00000177666	-0.0815664396430813	[1236,988]	[892,812]	-1	hSpCas9	negative selection	4679398
821797	821819	11	-	27760321	HL60	viability	ATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.36792494380884366	[1126,1049]	[1177,1115]	4	hSpCas9	negative selection	4679399
822385	822407	11	+	27760321	HL60	viability	GTCCCGTGGAAGCGCTACGTGG	PNPLA2	ENSG00000177666	0.1338984999944236	[668,599]	[668,460]	1	hSpCas9	negative selection	4679400
822466	822488	11	-	27760321	HL60	viability	TGTCACTCTCGCCCGAGAAGGG	PNPLA2	ENSG00000177666	0.0967593528416325	[353,304]	[353,215]	1	hSpCas9	negative selection	4679401
823567	823589	11	+	27760321	HL60	viability	TGCGCTTTCTGCAGCGGAACGG	PNPLA2	ENSG00000177666	0.6653425425035954	[548,420]	[642,602]	7	hSpCas9	negative selection	4679402
819839	819861	11	+	27760321	HT1080	viability	ACGCACATCTACGGCGCCTCGG	PNPLA2	ENSG00000177666	0.7442698984215956	[988,771]	[367,827]	4	hSpCas9	negative selection	4762861
821797	821819	11	-	27760321	HT1080	viability	ATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.2771992622243862	[1049,819]	[230,390]	-1	hSpCas9	negative selection	4762862
822385	822407	11	+	27760321	HT1080	viability	GTCCCGTGGAAGCGCTACGTGG	PNPLA2	ENSG00000177666	1.5118902145221127	[599,467]	[398,833]	8	hSpCas9	negative selection	4762863
822466	822488	11	-	27760321	HT1080	viability	TGTCACTCTCGCCCGAGAAGGG	PNPLA2	ENSG00000177666	0.4085440124883612	[304,237]	[49,245]	2	hSpCas9	negative selection	4762864
823567	823589	11	+	27760321	HT1080	viability	TGCGCTTTCTGCAGCGGAACGG	PNPLA2	ENSG00000177666	2.005513826953059	[420,328]	[565,636]	9	hSpCas9	negative selection	4762865
819839	819861	11	+	27760321	HT29	viability after 7 days	ACGCACATCTACGGCGCCTCGG	PNPLA2	ENSG00000177666	0.5657877816366552	[988,771]	[1416,1742,1822]	8	hSpCas9	negative selection	4846324
821797	821819	11	-	27760321	HT29	viability after 7 days	ATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.31143329757789817	[1049,819]	[1112,923,890]	-4	hSpCas9	negative selection	4846325
822385	822407	11	+	27760321	HT29	viability after 7 days	GTCCCGTGGAAGCGCTACGTGG	PNPLA2	ENSG00000177666	0.2280887264271828	[599,467]	[1238,739,503]	3	hSpCas9	negative selection	4846326
822466	822488	11	-	27760321	HT29	viability after 7 days	TGTCACTCTCGCCCGAGAAGGG	PNPLA2	ENSG00000177666	0.3307623760238668	[304,237]	[445,514,358]	5	hSpCas9	negative selection	4846327
823567	823589	11	+	27760321	HT29	viability after 7 days	TGCGCTTTCTGCAGCGGAACGG	PNPLA2	ENSG00000177666	-0.025629732160640337	[420,328]	[557,514,362]	0	hSpCas9	negative selection	4846328
819839	819861	11	+	27760321	HT29	viability after 25 days	ACGCACATCTACGGCGCCTCGG	PNPLA2	ENSG00000177666	0.6878077460308833	[988,771]	[1643,1342,1900]	7	hSpCas9	negative selection	4929787
821797	821819	11	-	27760321	HT29	viability after 25 days	ATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.09681426447556696	[1049,819]	[835,1131,1042]	-1	hSpCas9	negative selection	4929788
822385	822407	11	+	27760321	HT29	viability after 25 days	GTCCCGTGGAAGCGCTACGTGG	PNPLA2	ENSG00000177666	0.435824730018313	[599,467]	[566,1119,801]	5	hSpCas9	negative selection	4929789
822466	822488	11	-	27760321	HT29	viability after 25 days	TGTCACTCTCGCCCGAGAAGGG	PNPLA2	ENSG00000177666	0.3287341835297953	[304,237]	[416,460,276]	3	hSpCas9	negative selection	4929790
823567	823589	11	+	27760321	HT29	viability after 25 days	TGCGCTTTCTGCAGCGGAACGG	PNPLA2	ENSG00000177666	0.9167626297419165	[420,328]	[784,804,840]	9	hSpCas9	negative selection	4929791
819839	819861	11	+	27760321	HT29	viability after 22 days	ACGCACATCTACGGCGCCTCGG	PNPLA2	ENSG00000177666	0.5179502124594833	[988,771]	[1447,1247,1678]	6	hSpCas9	negative selection	5013250
821797	821819	11	-	27760321	HT29	viability after 22 days	ATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.4638794316099367	[1049,819]	[747,935,666]	-4	hSpCas9	negative selection	5013251
822385	822407	11	+	27760321	HT29	viability after 22 days	GTCCCGTGGAAGCGCTACGTGG	PNPLA2	ENSG00000177666	0.6248792330191962	[599,467]	[1109,946,792]	7	hSpCas9	negative selection	5013252
822466	822488	11	-	27760321	HT29	viability after 22 days	TGTCACTCTCGCCCGAGAAGGG	PNPLA2	ENSG00000177666	0.7209136562301421	[304,237]	[605,586,354]	7	hSpCas9	negative selection	5013253
823567	823589	11	+	27760321	HT29	viability after 22 days	TGCGCTTTCTGCAGCGGAACGG	PNPLA2	ENSG00000177666	0.9821057507355414	[420,328]	[728,951,891]	9	hSpCas9	negative selection	5013254
819839	819861	11	+	27760321	HT29	viability after 19 days	ACGCACATCTACGGCGCCTCGG	PNPLA2	ENSG00000177666	0.36316663829813867	[988,771]	[1626,1086,1208]	3	hSpCas9	negative selection	5096713
821797	821819	11	-	27760321	HT29	viability after 19 days	ATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.14871739407765028	[1049,819]	[1500,1035,432]	-1	hSpCas9	negative selection	5096714
822385	822407	11	+	27760321	HT29	viability after 19 days	GTCCCGTGGAAGCGCTACGTGG	PNPLA2	ENSG00000177666	0.6467126782239591	[599,467]	[1104,814,962]	6	hSpCas9	negative selection	5096715
822466	822488	11	-	27760321	HT29	viability after 19 days	TGTCACTCTCGCCCGAGAAGGG	PNPLA2	ENSG00000177666	0.863909775587804	[304,237]	[560,795,345]	8	hSpCas9	negative selection	5096716
823567	823589	11	+	27760321	HT29	viability after 19 days	TGCGCTTTCTGCAGCGGAACGG	PNPLA2	ENSG00000177666	0.9181998075131229	[420,328]	[685,732,991]	8	hSpCas9	negative selection	5096717
819839	819861	11	+	27760321	HT29	viability after 16 days	ACGCACATCTACGGCGCCTCGG	PNPLA2	ENSG00000177666	0.5999511532707993	[988,771]	[1347,1315,1805]	7	hSpCas9	negative selection	5180176
821797	821819	11	-	27760321	HT29	viability after 16 days	ATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.15809733117527136	[1049,819]	[986,789,1043]	-2	hSpCas9	negative selection	5180177
822385	822407	11	+	27760321	HT29	viability after 16 days	GTCCCGTGGAAGCGCTACGTGG	PNPLA2	ENSG00000177666	0.5881375243754617	[599,467]	[1163,640,920]	6	hSpCas9	negative selection	5180178
822466	822488	11	-	27760321	HT29	viability after 16 days	TGTCACTCTCGCCCGAGAAGGG	PNPLA2	ENSG00000177666	0.6085535542882956	[304,237]	[584,495,318]	7	hSpCas9	negative selection	5180179
823567	823589	11	+	27760321	HT29	viability after 16 days	TGCGCTTTCTGCAGCGGAACGG	PNPLA2	ENSG00000177666	0.5871954717827882	[420,328]	[780,560,564]	6	hSpCas9	negative selection	5180180
819839	819861	11	+	27760321	HT29	viability after 13 days	ACGCACATCTACGGCGCCTCGG	PNPLA2	ENSG00000177666	0.5904830727848815	[988,771]	[1337,1610,1657]	7	hSpCas9	negative selection	5263639
821797	821819	11	-	27760321	HT29	viability after 13 days	ATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.09697886511864073	[1049,819]	[998,1156,893]	-1	hSpCas9	negative selection	5263640
822385	822407	11	+	27760321	HT29	viability after 13 days	GTCCCGTGGAAGCGCTACGTGG	PNPLA2	ENSG00000177666	0.5562408185377906	[599,467]	[720,1186,829]	7	hSpCas9	negative selection	5263641
822466	822488	11	-	27760321	HT29	viability after 13 days	TGTCACTCTCGCCCGAGAAGGG	PNPLA2	ENSG00000177666	0.5626604873574139	[304,237]	[389,647,363]	7	hSpCas9	negative selection	5263642
823567	823589	11	+	27760321	HT29	viability after 13 days	TGCGCTTTCTGCAGCGGAACGG	PNPLA2	ENSG00000177666	0.5157214782090741	[420,328]	[582,676,606]	6	hSpCas9	negative selection	5263643
819839	819861	11	+	27760321	HT29	viability after 10 days	ACGCACATCTACGGCGCCTCGG	PNPLA2	ENSG00000177666	0.6512223036746347	[988,771]	[1461,1977,1745]	8	hSpCas9	negative selection	5347102
821797	821819	11	-	27760321	HT29	viability after 10 days	ATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.17640082124691991	[1049,819]	[880,778,1422]	-2	hSpCas9	negative selection	5347103
822385	822407	11	+	27760321	HT29	viability after 10 days	GTCCCGTGGAAGCGCTACGTGG	PNPLA2	ENSG00000177666	0.7898892773206353	[599,467]	[1139,1320,1004]	9	hSpCas9	negative selection	5347104
822466	822488	11	-	27760321	HT29	viability after 10 days	TGTCACTCTCGCCCGAGAAGGG	PNPLA2	ENSG00000177666	0.170519674925403	[304,237]	[399,383,360]	2	hSpCas9	negative selection	5347105
823567	823589	11	+	27760321	HT29	viability after 10 days	TGCGCTTTCTGCAGCGGAACGG	PNPLA2	ENSG00000177666	0.4665441926616649	[420,328]	[993,612,339]	6	hSpCas9	negative selection	5347106
819839	819861	11	+	27760321	MOLM13	viability	ACGCACATCTACGGCGCCTCGG	PNPLA2	ENSG00000177666	-0.43927873358679004	[1236,988]	[528,401]	-3	hSpCas9	negative selection	5430565
821797	821819	11	-	27760321	MOLM13	viability	ATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.8841178407788699	[1126,1049]	[226,422]	-5	hSpCas9	negative selection	5430566
822385	822407	11	+	27760321	MOLM13	viability	GTCCCGTGGAAGCGCTACGTGG	PNPLA2	ENSG00000177666	0.1922600985092563	[668,599]	[508,322]	1	hSpCas9	negative selection	5430567
822466	822488	11	-	27760321	MOLM13	viability	TGTCACTCTCGCCCGAGAAGGG	PNPLA2	ENSG00000177666	-1.3840075172687496	[353,304]	[110,36]	-7	hSpCas9	negative selection	5430568
823567	823589	11	+	27760321	MOLM13	viability	TGCGCTTTCTGCAGCGGAACGG	PNPLA2	ENSG00000177666	1.0764024252744921	[548,420]	[919,276]	7	hSpCas9	negative selection	5430569
818900	818923	11	+	27661255	K562	viability	GGGCGGCCCCAGTCAGACGCAGG	PNPLA2	ENSG00000177666	-0.08197977057138295	[333,377]	[300,239]	-3	dCas9-KRAB	negative selection	5502896
818921	818944	11	+	27661255	K562	viability	GGCAGCCCCAAAGCCTGAACAGG	PNPLA2	ENSG00000177666	0.052764296078652295	[1079,1117]	[936,886]	1	dCas9-KRAB	negative selection	5502897
818937	818960	11	+	27661255	K562	viability	GAACAGGCAGGGCCAGACCCAGG	PNPLA2	ENSG00000177666	-1.2669734386777374	[457,384]	[155,126]	-8	dCas9-KRAB	negative selection	5502898
819653	819676	11	+	27661255	K562	viability	GGCGAGCAGGCGGCTCACAGAGG	PNPLA2	ENSG00000177666	0.23451937595241035	[382,421]	[436,326]	7	dCas9-KRAB	negative selection	5502899
819995	820018	11	+	27661255	K562	viability	GCGAGTCGGTGGGTACCGTGGGG	PNPLA2	ENSG00000177666	0.009943373836767095	[772,765]	[611,624]	0	dCas9-KRAB	negative selection	5502900
819172	819195	11	-	27661255	K562	viability	GTCCCTGGACAGAGGCGCACCGG	PNPLA2	ENSG00000177666	0.37119960675813546	[270,373]	[367,299]	9	dCas9-KRAB	negative selection	5502901
820010	820033	11	-	27661255	K562	viability	GCGGACCGGAACCCTCCCCACGG	PNPLA2	ENSG00000177666	-0.052846056977023936	[2305,2224]	[1884,1626]	-2	dCas9-KRAB	negative selection	5502902
821797	821820	11	-	27260156	BXPC3	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.23398128315389322	[1191]	[1266,1429,1611,1584]	5	hSpCas9	negative selection	5563517
822467	822490	11	-	27260156	BXPC3	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.5043380443162251	[88]	[114,150,143,115]	9	hSpCas9	negative selection	5563518
822388	822411	11	+	27260156	BXPC3	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.22555422774415135	[129]	[110,201,151,173]	5	hSpCas9	negative selection	5563519
821789	821812	11	+	27260156	BXPC3	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.2117514042541836	[358]	[450,383,397,512]	4	hSpCas9	negative selection	5627766
823565	823588	11	-	27260156	BXPC3	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.18266996907991961	[183]	[168,217,233,261]	4	hSpCas9	negative selection	5627767
823529	823552	11	+	27260156	BXPC3	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.30708121294643864	[152]	[88,131,123,181]	-6	hSpCas9	negative selection	5627768
821797	821820	11	-	27260156	A673	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.237227792281949	[1191]	[1746,1599,1716,1689]	5	hSpCas9	negative selection	5684768
822467	822490	11	-	27260156	A673	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.12726265897756184	[88]	[138,82,86,163]	3	hSpCas9	negative selection	5684769
822388	822411	11	+	27260156	A673	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.3905592706618941	[129]	[169,181,172,294]	8	hSpCas9	negative selection	5684770
821789	821812	11	+	27260156	A673	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	-0.039734360907990096	[358]	[359,422,454,431]	-1	hSpCas9	negative selection	5749017
823565	823588	11	-	27260156	A673	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.11905987658936001	[183]	[246,231,230,250]	3	hSpCas9	negative selection	5749018
823529	823552	11	+	27260156	A673	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.11848734317011189	[152]	[160,123,182,210]	-3	hSpCas9	negative selection	5749019
821797	821820	11	-	27260156	A375	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.10116698142893665	[1191]	[1268,1387,1612,968]	-1	hSpCas9	negative selection	5806019
822467	822490	11	-	27260156	A375	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.4232207646686841	[88]	[22,162,45,87]	-5	hSpCas9	negative selection	5806020
822388	822411	11	+	27260156	A375	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	-0.17050219535942213	[129]	[199,127,115,98]	-2	hSpCas9	negative selection	5806021
821789	821812	11	+	27260156	A375	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	-0.20162847255298455	[358]	[167,508,436,361]	-3	hSpCas9	negative selection	5870268
823565	823588	11	-	27260156	A375	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.20659153627077842	[183]	[224,357,219,207]	3	hSpCas9	negative selection	5870269
823529	823552	11	+	27260156	A375	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.5719483736049191	[152]	[80,61,180,144]	-6	hSpCas9	negative selection	5870270
821797	821820	11	-	27260156	COLO741	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.15797772096031926	[1191]	[1771,1725,1608]	3	hSpCas9	negative selection	5927270
822467	822490	11	-	27260156	COLO741	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.28270998639314815	[88]	[109,200,103]	6	hSpCas9	negative selection	5927271
822388	822411	11	+	27260156	COLO741	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.4071953844925902	[129]	[219,215,223]	8	hSpCas9	negative selection	5927272
821789	821812	11	+	27260156	COLO741	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.38768926785957003	[358]	[850,441,531]	7	hSpCas9	negative selection	5991519
823565	823588	11	-	27260156	COLO741	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.16062310196307128	[183]	[286,284,220]	3	hSpCas9	negative selection	5991520
823529	823552	11	+	27260156	COLO741	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.12692869694487152	[152]	[256,188,102]	-3	hSpCas9	negative selection	5991521
821797	821820	11	-	27260156	CAL120	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.3332764323687658	[1191]	[2115,2006,1525]	5	hSpCas9	negative selection	6048521
822467	822490	11	-	27260156	CAL120	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.04351297890604355	[88]	[118,47,174]	0	hSpCas9	negative selection	6048522
822388	822411	11	+	27260156	CAL120	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.6805488691789274	[129]	[259,211,304]	8	hSpCas9	negative selection	6048523
821789	821812	11	+	27260156	CAL120	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.2264238799917247	[358]	[806,363,440]	3	hSpCas9	negative selection	6112770
823565	823588	11	-	27260156	CAL120	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.6269207378008471	[183]	[405,336,325]	8	hSpCas9	negative selection	6112771
823529	823552	11	+	27260156	CAL120	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	1.1433391950741658	[152]	[422,257,577]	9	hSpCas9	negative selection	6112772
821797	821820	11	-	27260156	CADOES1	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.10419392809817518	[1191]	[1209,1294,1345,904]	1	hSpCas9	negative selection	6169772
822467	822490	11	-	27260156	CADOES1	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.030188036303671062	[88]	[62,88,98,72]	0	hSpCas9	negative selection	6169773
822388	822411	11	+	27260156	CADOES1	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.45582021686915075	[129]	[185,137,127,212]	7	hSpCas9	negative selection	6169774
821789	821812	11	+	27260156	CADOES1	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	-0.004747584134615068	[358]	[326,394,284,323]	0	hSpCas9	negative selection	6234021
823565	823588	11	-	27260156	CADOES1	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.3513926386576516	[183]	[236,207,266,158]	6	hSpCas9	negative selection	6234022
823529	823552	11	+	27260156	CADOES1	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.2951289441243885	[152]	[145,101,119,94]	-5	hSpCas9	negative selection	6234023
821797	821820	11	-	27260156	EWS502	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.14260526272531426	[1191]	[1496,1255,1573,1225]	2	hSpCas9	negative selection	6291023
822467	822490	11	-	27260156	EWS502	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.3673272107448824	[88]	[19,74,69,137]	-6	hSpCas9	negative selection	6291024
822388	822411	11	+	27260156	EWS502	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.558003896226543	[129]	[196,247,149,213]	8	hSpCas9	negative selection	6291025
821789	821812	11	+	27260156	EWS502	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.19932380271875616	[358]	[432,349,351,625]	3	hSpCas9	negative selection	6355272
823565	823588	11	-	27260156	EWS502	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.05253516767320576	[183]	[142,180,289,202]	0	hSpCas9	negative selection	6355273
823529	823552	11	+	27260156	EWS502	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.5955666437721148	[152]	[107,81,65,177]	-7	hSpCas9	negative selection	6355274
821797	821820	11	-	27260156	EW8	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.272935855722962	[1191]	[1157,1224,1027,1276]	5	hSpCas9	negative selection	6412274
822467	822490	11	-	27260156	EW8	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.278571111483517	[88]	[62,39,52,82]	-5	hSpCas9	negative selection	6412275
822388	822411	11	+	27260156	EW8	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.2633730378286272	[129]	[80,161,123,133]	5	hSpCas9	negative selection	6412276
821789	821812	11	+	27260156	EW8	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.2014119295829734	[358]	[416,329,276,331]	3	hSpCas9	negative selection	6476523
823565	823588	11	-	27260156	EW8	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.014681819673094454	[183]	[201,124,76,215]	0	hSpCas9	negative selection	6476524
823529	823552	11	+	27260156	EW8	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.34100522738852335	[152]	[142,94,75,85]	-6	hSpCas9	negative selection	6476525
821797	821820	11	-	27260156	CORL105	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.32460195480170273	[1191]	[1555,1620,2208,1671]	6	hSpCas9	negative selection	6533525
822467	822490	11	-	27260156	CORL105	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.1854615349555031	[88]	[84,48,129,108]	-3	hSpCas9	negative selection	6533526
822388	822411	11	+	27260156	CORL105	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.31895301927257513	[129]	[122,176,333,145]	6	hSpCas9	negative selection	6533527
821789	821812	11	+	27260156	CORL105	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.3657245640808291	[358]	[379,474,542,762]	6	hSpCas9	negative selection	6597774
823565	823588	11	-	27260156	CORL105	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.020912066117487083	[183]	[163,229,256,226]	0	hSpCas9	negative selection	6597775
823529	823552	11	+	27260156	CORL105	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-1.2673148035316901	[152]	[71,64,63,94]	-9	hSpCas9	negative selection	6597776
821797	821820	11	-	27260156	HS294T	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.30967731121359754	[1191]	[656,511,414,716]	4	hSpCas9	negative selection	6654776
822467	822490	11	-	27260156	HS294T	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.05819316162296673	[88]	[25,40,29,35]	-1	hSpCas9	negative selection	6654777
822388	822411	11	+	27260156	HS294T	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.6352824972855735	[129]	[130,68,49,52]	8	hSpCas9	negative selection	6654778
821789	821812	11	+	27260156	HS294T	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.026042552289131493	[358]	[95,123,177,177]	0	hSpCas9	negative selection	6719025
823565	823588	11	-	27260156	HS294T	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.17279261042466976	[183]	[69,64,101,85]	2	hSpCas9	negative selection	6719026
823529	823552	11	+	27260156	HS294T	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.20947562217812954	[152]	[43,40,36,89]	-3	hSpCas9	negative selection	6719027
821797	821820	11	-	27260156	HCC44	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.20744927639580601	[1191]	[1539,1518,1997,1246]	3	hSpCas9	negative selection	6776027
822467	822490	11	-	27260156	HCC44	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.5179975233237744	[88]	[232,78,143,136]	8	hSpCas9	negative selection	6776028
822388	822411	11	+	27260156	HCC44	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.4503480734042098	[129]	[218,135,270,198]	7	hSpCas9	negative selection	6776029
821789	821812	11	+	27260156	HCC44	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.3126912454553856	[358]	[493,417,749,407]	5	hSpCas9	negative selection	6840276
823565	823588	11	-	27260156	HCC44	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.3778717411893784	[183]	[206,151,175,113]	-5	hSpCas9	negative selection	6840277
823529	823552	11	+	27260156	HCC44	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.02319200021061052	[152]	[223,198,113,134]	0	hSpCas9	negative selection	6840278
821797	821820	11	-	27260156	G402	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.05200380347391809	[1191]	[1420,1383,1908,917]	0	hSpCas9	negative selection	6897278
822467	822490	11	-	27260156	G402	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-1.38274759539526	[88]	[1,54,73,30]	-9	hSpCas9	negative selection	6897279
822388	822411	11	+	27260156	G402	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.49742145026815043	[129]	[375,208,86,242]	6	hSpCas9	negative selection	6897280
821789	821812	11	+	27260156	G402	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	-0.2892046660184413	[358]	[486,278,311,367]	-4	hSpCas9	negative selection	6961527
823565	823588	11	-	27260156	G402	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.04770077918901805	[183]	[302,220,104,249]	0	hSpCas9	negative selection	6961528
823529	823552	11	+	27260156	G402	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.4309176858898136	[152]	[123,291,21,122]	-5	hSpCas9	negative selection	6961529
821797	821820	11	-	27260156	L33	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.18752485549994513	[1191]	[1273,496,881,1539]	4	hSpCas9	negative selection	7018529
822467	822490	11	-	27260156	L33	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.011139431574152425	[88]	[71,28,40,144]	0	hSpCas9	negative selection	7018530
822388	822411	11	+	27260156	L33	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	-0.01732724106899619	[129]	[105,57,92,118]	0	hSpCas9	negative selection	7018531
821789	821812	11	+	27260156	L33	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.2698939246822624	[358]	[303,201,324,420]	6	hSpCas9	negative selection	7082778
823565	823588	11	-	27260156	L33	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.30310634227109934	[183]	[162,84,184,244]	6	hSpCas9	negative selection	7082779
823529	823552	11	+	27260156	L33	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.6373515500128846	[152]	[106,46,70,58]	-9	hSpCas9	negative selection	7082780
821797	821820	11	-	27260156	K562	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.781642498587618	[1191]	[1883,2095,1920,1430]	8	hSpCas9	negative selection	7139780
822467	822490	11	-	27260156	K562	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.6230605048551969	[88]	[51,18,68,61]	-6	hSpCas9	negative selection	7139781
822388	822411	11	+	27260156	K562	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.0110041419451119	[129]	[96,183,92,94]	0	hSpCas9	negative selection	7139782
821789	821812	11	+	27260156	K562	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.004280044377027337	[358]	[187,208,588,278]	0	hSpCas9	negative selection	7204029
823565	823588	11	-	27260156	K562	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.9749428156211798	[183]	[488,227,457,137]	9	hSpCas9	negative selection	7204030
823529	823552	11	+	27260156	K562	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.12536226848188403	[152]	[111,169,122,96]	-2	hSpCas9	negative selection	7204031
821797	821820	11	-	27260156	HT29	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.11055453284328531	[1191]	[1742,1553,1477,1492]	2	hSpCas9	negative selection	7261031
822467	822490	11	-	27260156	HT29	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.1256206706029337	[88]	[87,113,82,109]	-3	hSpCas9	negative selection	7261032
822388	822411	11	+	27260156	HT29	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.302526996674485	[129]	[136,187,269,179]	6	hSpCas9	negative selection	7261033
821789	821812	11	+	27260156	HT29	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.2453401282595959	[358]	[536,605,507,433]	5	hSpCas9	negative selection	7325280
823565	823588	11	-	27260156	HT29	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.17941727070518376	[183]	[305,211,268,227]	3	hSpCas9	negative selection	7325281
823529	823552	11	+	27260156	HT29	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.36616837312025496	[152]	[264,161,105,63]	-6	hSpCas9	negative selection	7325282
821797	821820	11	-	27260156	MHHES1	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.2938374612369683	[1191]	[1939,1964,1605,1205]	5	hSpCas9	negative selection	7382282
822467	822490	11	-	27260156	MHHES1	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.06148628247671839	[88]	[169,92,95,43]	-1	hSpCas9	negative selection	7382283
822388	822411	11	+	27260156	MHHES1	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.09282265987809102	[129]	[146,215,138,129]	1	hSpCas9	negative selection	7382284
821789	821812	11	+	27260156	MHHES1	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.20459231127481298	[358]	[439,409,586,418]	4	hSpCas9	negative selection	7446531
823565	823588	11	-	27260156	MHHES1	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.5319577585010856	[183]	[197,272,374,324]	8	hSpCas9	negative selection	7446532
823529	823552	11	+	27260156	MHHES1	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.586085304706337	[152]	[89,231,109,48]	-8	hSpCas9	negative selection	7446533
821797	821820	11	-	27260156	MEWO	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.30045254590971693	[1191]	[1468,1247,1421]	6	hSpCas9	negative selection	7503533
822467	822490	11	-	27260156	MEWO	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.6057947518402835	[88]	[43,144,174]	9	hSpCas9	negative selection	7503534
822388	822411	11	+	27260156	MEWO	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.5236934038856103	[129]	[160,138,221]	9	hSpCas9	negative selection	7503535
821789	821812	11	+	27260156	MEWO	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.09816018576941654	[358]	[534,248,328]	2	hSpCas9	negative selection	7567782
823565	823588	11	-	27260156	MEWO	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.4071805271239035	[183]	[219,264,197]	8	hSpCas9	negative selection	7567783
823529	823552	11	+	27260156	MEWO	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.3793000399933788	[152]	[140,133,60]	-7	hSpCas9	negative selection	7567784
821797	821820	11	-	27260156	LNCAPCLONEFGC	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	-0.1182763153509454	[1191]	[985,899,1082,1028]	-2	hSpCas9	negative selection	7624784
822467	822490	11	-	27260156	LNCAPCLONEFGC	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-1.460080694581797	[88]	[6,26,50,35]	-9	hSpCas9	negative selection	7624785
822388	822411	11	+	27260156	LNCAPCLONEFGC	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.5149451537160858	[129]	[106,139,322,128]	7	hSpCas9	negative selection	7624786
821789	821812	11	+	27260156	LNCAPCLONEFGC	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.2842727065441506	[358]	[325,451,459,352]	4	hSpCas9	negative selection	7689033
823565	823588	11	-	27260156	LNCAPCLONEFGC	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.6393930294678899	[183]	[72,373,357,243]	8	hSpCas9	negative selection	7689034
823529	823552	11	+	27260156	LNCAPCLONEFGC	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-1.11194659086756	[152]	[19,85,91,61]	-9	hSpCas9	negative selection	7689035
821797	821820	11	-	27260156	PANC0327	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.11511257865728863	[1191]	[1549,1004,973,1108]	1	hSpCas9	negative selection	7746035
822467	822490	11	-	27260156	PANC0327	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-1.493692670249775	[88]	[31,55,15,4]	-9	hSpCas9	negative selection	7746036
822388	822411	11	+	27260156	PANC0327	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	-0.1338591121357129	[129]	[204,66,59,101]	-2	hSpCas9	negative selection	7746037
821789	821812	11	+	27260156	PANC0327	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.31678752162847645	[358]	[410,210,498,492]	5	hSpCas9	negative selection	7810284
823565	823588	11	-	27260156	PANC0327	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.33826627208920823	[183]	[226,152,71,69]	-5	hSpCas9	negative selection	7810285
823529	823552	11	+	27260156	PANC0327	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.11319183391433074	[152]	[87,127,52,229]	-2	hSpCas9	negative selection	7810286
821797	821820	11	-	27260156	NCIH2009	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.10999804952169878	[1191]	[2254,1547,1680]	1	hSpCas9	negative selection	7867286
822467	822490	11	-	27260156	NCIH2009	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.8466732851881513	[88]	[99,36,76]	-7	hSpCas9	negative selection	7867287
822388	822411	11	+	27260156	NCIH2009	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.27968171249986007	[129]	[287,188,197]	4	hSpCas9	negative selection	7867288
821789	821812	11	+	27260156	NCIH2009	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.1311881525621721	[358]	[869,462,378]	1	hSpCas9	negative selection	7931535
823565	823588	11	-	27260156	NCIH2009	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.3624766061696242	[183]	[465,260,291]	5	hSpCas9	negative selection	7931536
823529	823552	11	+	27260156	NCIH2009	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.255032010415299	[152]	[288,167,101]	-3	hSpCas9	negative selection	7931537
821797	821820	11	-	27260156	NCIH1373	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.17349203697542248	[1191]	[1386,1580,1166,495]	1	hSpCas9	negative selection	7988537
822467	822490	11	-	27260156	NCIH1373	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.6258468027246078	[88]	[92,46,10,30]	-6	hSpCas9	negative selection	7988538
822388	822411	11	+	27260156	NCIH1373	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.6568433185977374	[129]	[215,181,369,37]	6	hSpCas9	negative selection	7988539
821789	821812	11	+	27260156	NCIH1373	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	-0.1782942814123255	[358]	[454,178,450,96]	-2	hSpCas9	negative selection	8052786
823565	823588	11	-	27260156	NCIH1373	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.3581406988014606	[183]	[94,134,292,140]	3	hSpCas9	negative selection	8052787
823529	823552	11	+	27260156	NCIH1373	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.9924396503902357	[152]	[102,60,97,22]	-7	hSpCas9	negative selection	8052788
821797	821820	11	-	27260156	PATU8902	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.20425009975001718	[1191]	[2049,1254,1601,2925]	2	hSpCas9	negative selection	8109788
822467	822490	11	-	27260156	PATU8902	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.3898243957934655	[88]	[53,315,127,160]	4	hSpCas9	negative selection	8109789
822388	822411	11	+	27260156	PATU8902	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.8248226170002806	[129]	[406,366,50,551]	8	hSpCas9	negative selection	8109790
821789	821812	11	+	27260156	PATU8902	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	-0.09194554728748927	[358]	[357,812,258,503]	-1	hSpCas9	negative selection	8174037
823565	823588	11	-	27260156	PATU8902	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	1.1451697428640326	[183]	[916,346,348,718]	9	hSpCas9	negative selection	8174038
823529	823552	11	+	27260156	PATU8902	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-1.1886035125082308	[152]	[188,91,11,100]	-8	hSpCas9	negative selection	8174039
821797	821820	11	-	27260156	PANC1	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.004770891824332324	[1191]	[960,1178,1150,861]	0	hSpCas9	negative selection	8231039
822467	822490	11	-	27260156	PANC1	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.704390359226398	[88]	[60,82,44,10]	-7	hSpCas9	negative selection	8231040
822388	822411	11	+	27260156	PANC1	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.27924823649909003	[129]	[176,161,90,116]	4	hSpCas9	negative selection	8231041
821789	821812	11	+	27260156	PANC1	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.07657014906911219	[358]	[422,505,185,229]	1	hSpCas9	negative selection	8295288
823565	823588	11	-	27260156	PANC1	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.02968411839401064	[183]	[130,154,87,229]	0	hSpCas9	negative selection	8295289
823529	823552	11	+	27260156	PANC1	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.3815930678615127	[152]	[146,136,71,58]	-5	hSpCas9	negative selection	8295290
821797	821820	11	-	27260156	PANC0813	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.05706737413568219	[1191]	[1366,1777,1408,1271]	0	hSpCas9	negative selection	8352290
822467	822490	11	-	27260156	PANC0813	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.010766070174457631	[88]	[53,64,40,247]	0	hSpCas9	negative selection	8352291
822388	822411	11	+	27260156	PANC0813	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.3313561094932267	[129]	[244,161,224,143]	5	hSpCas9	negative selection	8352292
821789	821812	11	+	27260156	PANC0813	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.07082449541881508	[358]	[534,523,403,322]	1	hSpCas9	negative selection	8416539
823565	823588	11	-	27260156	PANC0813	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.1743581220124386	[183]	[297,250,239,193]	3	hSpCas9	negative selection	8416540
823529	823552	11	+	27260156	PANC0813	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.3007785511815515	[152]	[229,39,100,215]	-5	hSpCas9	negative selection	8416541
821797	821820	11	-	27260156	RDES	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.17974371998813754	[1191]	[1374,1437,1659,1775]	3	hSpCas9	negative selection	8473541
822467	822490	11	-	27260156	RDES	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.2961305542426693	[88]	[66,76,64,132]	-5	hSpCas9	negative selection	8473542
822388	822411	11	+	27260156	RDES	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.6091145010880727	[129]	[112,219,362,243]	8	hSpCas9	negative selection	8473543
821789	821812	11	+	27260156	RDES	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.5131070684760567	[358]	[539,502,598,737]	7	hSpCas9	negative selection	8537790
823565	823588	11	-	27260156	RDES	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.03460946350925642	[183]	[166,131,182,379]	0	hSpCas9	negative selection	8537791
823529	823552	11	+	27260156	RDES	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.7931585218854973	[152]	[115,89,128,59]	-8	hSpCas9	negative selection	8537792
821797	821820	11	-	27260156	PC3	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.09992977061943242	[1191]	[848,1145,2310,1253]	2	hSpCas9	negative selection	8594792
822467	822490	11	-	27260156	PC3	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.5120171247379304	[88]	[136,80,86,164]	9	hSpCas9	negative selection	8594793
822388	822411	11	+	27260156	PC3	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.3206054774469722	[129]	[153,126,310,92]	7	hSpCas9	negative selection	8594794
821789	821812	11	+	27260156	PC3	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	8.417337836968963e-05	[358]	[160,438,553,410]	0	hSpCas9	negative selection	8659041
823565	823588	11	-	27260156	PC3	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.20438262446414623	[183]	[136,219,163,320]	4	hSpCas9	negative selection	8659042
823529	823552	11	+	27260156	PC3	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.24079319580200842	[152]	[67,78,427,74]	-5	hSpCas9	negative selection	8659043
821797	821820	11	-	27260156	PATU8988T	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.1540963777180515	[1191]	[1310,1312,1147,1365]	2	hSpCas9	negative selection	8716043
822467	822490	11	-	27260156	PATU8988T	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.14879100657714872	[88]	[154,61,140,12]	2	hSpCas9	negative selection	8716044
822388	822411	11	+	27260156	PATU8988T	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.36466838911977373	[129]	[287,127,87,138]	6	hSpCas9	negative selection	8716045
821789	821812	11	+	27260156	PATU8988T	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.01621673652508726	[358]	[154,435,355,473]	0	hSpCas9	negative selection	8780292
823565	823588	11	-	27260156	PATU8988T	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.35106117596383934	[183]	[390,132,220,146]	6	hSpCas9	negative selection	8780293
823529	823552	11	+	27260156	PATU8988T	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.35313460672187746	[152]	[218,135,39,66]	-5	hSpCas9	negative selection	8780294
821797	821820	11	-	27260156	T47D	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.2960683179511956	[1191]	[1747,1606,1728,1744]	6	hSpCas9	negative selection	8837294
822467	822490	11	-	27260156	T47D	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.5585117523904373	[88]	[112,48,49,71]	-8	hSpCas9	negative selection	8837295
822388	822411	11	+	27260156	T47D	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.5081919424594237	[129]	[149,182,283,246]	9	hSpCas9	negative selection	8837296
821789	821812	11	+	27260156	T47D	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.19139029993451967	[358]	[415,461,573,456]	4	hSpCas9	negative selection	8901543
823565	823588	11	-	27260156	T47D	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.034318618897527076	[183]	[213,193,187,243]	0	hSpCas9	negative selection	8901544
823529	823552	11	+	27260156	T47D	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.4734335550816884	[152]	[147,94,148,123]	-7	hSpCas9	negative selection	8901545
821797	821820	11	-	27260156	SU8686	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.1110352890650046	[1191]	[1258,1194,1145,1548]	1	hSpCas9	negative selection	8958545
822467	822490	11	-	27260156	SU8686	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.31522280590460916	[88]	[88,76,57,52]	-5	hSpCas9	negative selection	8958546
822388	822411	11	+	27260156	SU8686	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.7228636597194049	[129]	[255,156,194,248]	9	hSpCas9	negative selection	8958547
821789	821812	11	+	27260156	SU8686	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.24671053759991285	[358]	[355,383,482,487]	4	hSpCas9	negative selection	9022794
823565	823588	11	-	27260156	SU8686	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.613337429318098	[183]	[246,270,298,306]	8	hSpCas9	negative selection	9022795
823529	823552	11	+	27260156	SU8686	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.6523348148683625	[152]	[101,40,144,106]	-7	hSpCas9	negative selection	9022796
821797	821820	11	-	27260156	SKES1	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.28996706361724844	[1191]	[1633,1279,1416,1470]	6	hSpCas9	negative selection	9079796
822467	822490	11	-	27260156	SKES1	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.43434442068940826	[88]	[157,147,92,91]	8	hSpCas9	negative selection	9079797
822388	822411	11	+	27260156	SKES1	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.5918892246533307	[129]	[287,172,178,154]	9	hSpCas9	negative selection	9079798
821789	821812	11	+	27260156	SKES1	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.23308720269690256	[358]	[381,470,395,429]	5	hSpCas9	negative selection	9144045
823565	823588	11	-	27260156	SKES1	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.2949084841409162	[183]	[238,170,124,84]	-6	hSpCas9	negative selection	9144046
823529	823552	11	+	27260156	SKES1	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.8062864285551095	[152]	[58,115,108,65]	-9	hSpCas9	negative selection	9144047
821797	821820	11	-	27260156	TOV112D	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.2653075779730587	[1191]	[1514,2063,1076,1247]	5	hSpCas9	negative selection	9201047
822467	822490	11	-	27260156	TOV112D	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.9825810313296337	[88]	[247,231,65,177]	9	hSpCas9	negative selection	9201048
822388	822411	11	+	27260156	TOV112D	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.17535476029457775	[129]	[94,197,190,112]	3	hSpCas9	negative selection	9201049
821789	821812	11	+	27260156	TOV112D	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	0.21356573350661617	[358]	[521,461,432,273]	4	hSpCas9	negative selection	9265296
823565	823588	11	-	27260156	TOV112D	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.14496899776175542	[183]	[199,158,153,287]	3	hSpCas9	negative selection	9265297
823529	823552	11	+	27260156	TOV112D	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.5866178046674142	[152]	[146,137,46,88]	-8	hSpCas9	negative selection	9265298
821797	821820	11	-	27260156	TC71	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.1854051392159537	[1191]	[1452,1353,1395,1620]	4	hSpCas9	negative selection	9322298
822467	822490	11	-	27260156	TC71	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.43949059035408844	[88]	[165,111,132,103]	8	hSpCas9	negative selection	9322299
822388	822411	11	+	27260156	TC71	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.037756130831925416	[129]	[130,164,170,101]	1	hSpCas9	negative selection	9322300
821789	821812	11	+	27260156	TC71	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	-0.06789884107138439	[358]	[349,341,363,415]	-2	hSpCas9	negative selection	9386547
823565	823588	11	-	27260156	TC71	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.04132805417492591	[183]	[275,192,162,177]	1	hSpCas9	negative selection	9386548
823529	823552	11	+	27260156	TC71	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	0.04397497171359377	[152]	[85,172,163,260]	1	hSpCas9	negative selection	9386549
821797	821820	11	-	27260156	TC32	viability	CATTCTCGCCGTCTGACACGCGG	PNPLA2	ENSG00000177666	0.14643418552389886	[1191]	[1216,802,1687,1436]	2	hSpCas9	negative selection	9443549
822467	822490	11	-	27260156	TC32	viability	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.3008026567003226	[88]	[69,97,141,108]	5	hSpCas9	negative selection	9443550
822388	822411	11	+	27260156	TC32	viability	CCGTGGAAGCGCTACGTGGATGG	PNPLA2	ENSG00000177666	0.318408133063526	[129]	[153,150,209,90]	5	hSpCas9	negative selection	9443551
821789	821812	11	+	27260156	TC32	viability	TCCCTGACCCGCGTGTCAGACGG	PNPLA2	ENSG00000177666	-0.22830256497627943	[358]	[365,163,298,347]	-4	hSpCas9	negative selection	9507798
823565	823588	11	-	27260156	TC32	viability	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.3092872942087923	[183]	[183,167,304,224]	5	hSpCas9	negative selection	9507799
823529	823552	11	+	27260156	TC32	viability	GCTGCGAGAGATGTGCAAGCAGG	PNPLA2	ENSG00000177666	-0.012573837144242095	[152]	[78,92,250,187]	0	hSpCas9	negative selection	9507800
819769	819792	11	-	27869803	HPAFII	viability after 27 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	-0.19466640329679918	[300]	[68,195,NaN]	-1	hSpCas9	negative selection	9544289
821796	821819	11	-	27869803	HPAFII	viability after 27 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.8567713688441204	[180]	[69,37,NaN]	-6	hSpCas9	negative selection	9544290
822467	822490	11	-	27869803	HPAFII	viability after 27 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-2.6460221841809046	[91]	[10,4,NaN]	-8	hSpCas9	negative selection	9544291
823565	823588	11	-	27869803	HPAFII	viability after 27 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.4182641469690933	[234]	[86,96,NaN]	-3	hSpCas9	negative selection	9544292
819769	819792	11	-	27869803	HPAFII	viability after 15 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	-0.23165769615343695	[300]	[330,240,NaN]	-3	hSpCas9	negative selection	9626738
821796	821819	11	-	27869803	HPAFII	viability after 15 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.5531831110369657	[180]	[192,94,NaN]	-5	hSpCas9	negative selection	9626739
822467	822490	11	-	27869803	HPAFII	viability after 15 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-0.8409029373618992	[91]	[69,45,NaN]	-7	hSpCas9	negative selection	9626740
823565	823588	11	-	27869803	HPAFII	viability after 15 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.13587694757708246	[234]	[338,161,NaN]	-2	hSpCas9	negative selection	9626741
819769	819792	11	-	27869803	ASPC1	viability after 36 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	-0.4047138869155031	[653]	[304,268,0]	-4	hSpCas9	negative selection	9709187
821796	821819	11	-	27869803	ASPC1	viability after 36 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.30800352284602867	[442]	[183,177,39]	-3	hSpCas9	negative selection	9709188
822467	822490	11	-	27869803	ASPC1	viability after 36 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-1.9794822124607239	[408]	[7,7,77]	-9	hSpCas9	negative selection	9709189
823565	823588	11	-	27869803	ASPC1	viability after 36 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.4573538022671894	[478]	[17,295,54]	-5	hSpCas9	negative selection	9709190
819769	819792	11	-	27869803	PATU8988S	viability after 35 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	-1.146881185048209	[643]	[174,58,NaN]	-8	hSpCas9	negative selection	9791636
821796	821819	11	-	27869803	PATU8988S	viability after 35 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.7504663355771866	[404]	[77,115,NaN]	-6	hSpCas9	negative selection	9791637
822467	822490	11	-	27869803	PATU8988S	viability after 35 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.24058205013044343	[250]	[90,147,NaN]	2	hSpCas9	negative selection	9791638
823565	823588	11	-	27869803	PATU8988S	viability after 35 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.18293972478079323	[368]	[93,167,NaN]	-2	hSpCas9	negative selection	9791639
819769	819792	11	-	27869803	PATU8988S	viability after 31 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	-0.6723750695578347	[643]	[205,103,NaN]	-6	hSpCas9	negative selection	9874085
821796	821819	11	-	27869803	PATU8988S	viability after 31 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-0.8281994710455645	[404]	[75,109,NaN]	-7	hSpCas9	negative selection	9874086
822467	822490	11	-	27869803	PATU8988S	viability after 31 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	0.1208852887638634	[250]	[70,156,NaN]	1	hSpCas9	negative selection	9874087
823565	823588	11	-	27869803	PATU8988S	viability after 31 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	0.1981263940057466	[368]	[148,193,NaN]	2	hSpCas9	negative selection	9874088
819769	819792	11	-	27869803	HPAFII	viability after 35 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.1573230205761419	[300]	[160,179,NaN]	1	hSpCas9	negative selection	9956534
821796	821819	11	-	27869803	HPAFII	viability after 35 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-1.6570261024816872	[180]	[21,36,NaN]	-7	hSpCas9	negative selection	9956535
822467	822490	11	-	27869803	HPAFII	viability after 35 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-4.169115881329835	[91]	[3,0,NaN]	-9	hSpCas9	negative selection	9956536
823565	823588	11	-	27869803	HPAFII	viability after 35 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-1.2867179731004332	[234]	[44,52,NaN]	-6	hSpCas9	negative selection	9956537
819769	819792	11	-	27869803	HPAFII	viability after 31 days	CGCCGACGTAGTAGACGCCGAGG	PNPLA2	ENSG00000177666	0.17393955204253664	[300]	[180,200,NaN]	1	hSpCas9	negative selection	10038983
821796	821819	11	-	27869803	HPAFII	viability after 31 days	ATTCTCGCCGTCTGACACGCGGG	PNPLA2	ENSG00000177666	-1.718274347493407	[180]	[27,33,NaN]	-7	hSpCas9	negative selection	10038984
822467	822490	11	-	27869803	HPAFII	viability after 31 days	GATGTCACTCTCGCCCGAGAAGG	PNPLA2	ENSG00000177666	-3.1576956755547343	[91]	[0,10,NaN]	-9	hSpCas9	negative selection	10038985
823565	823588	11	-	27869803	HPAFII	viability after 31 days	CGTTCCGCTGCAGAAAGCGCAGG	PNPLA2	ENSG00000177666	-0.5608275571382154	[234]	[131,42,NaN]	-4	hSpCas9	negative selection	10038986
821722	821745	11	-	28162770	P31FUJ	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.12229275440818291	[214]	[274]	1	hSpCas9	negative selection	10213695
821981	822004	11	-	28162770	P31FUJ	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	0.23205875592992786	[433]	[598]	2	hSpCas9	negative selection	10213696
822555	822578	11	-	28162770	P31FUJ	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	0.8984423288638741	[20]	[45]	8	hSpCas9	negative selection	10213697
822592	822615	11	-	28162770	P31FUJ	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	-0.4074807358273256	[113]	[100]	-4	hSpCas9	negative selection	10213698
819808	819831	11	+	28162770	P31FUJ	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	-0.12751330552961349	[316]	[340]	-1	hSpCas9	negative selection	10213699
819818	819841	11	-	28162770	P31FUJ	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	-0.46093099529997106	[293]	[250]	-4	hSpCas9	negative selection	10213700
819831	819854	11	-	28162770	P31FUJ	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	-0.15618092281146617	[164]	[173]	-1	hSpCas9	negative selection	10213701
821952	821975	11	+	28162770	P31FUJ	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	0.07300622510970667	[287]	[355]	0	hSpCas9	negative selection	10213702
821722	821745	11	-	28162770	TF1	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	NaN	[NaN]	[183]	1	hSpCas9	negative selection	10383061
821981	822004	11	-	28162770	TF1	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	NaN	[NaN]	[170]	1	hSpCas9	negative selection	10383062
822555	822578	11	-	28162770	TF1	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10383063
822592	822615	11	-	28162770	TF1	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	NaN	[NaN]	[156]	1	hSpCas9	negative selection	10383064
819808	819831	11	+	28162770	TF1	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	NaN	[NaN]	[231]	1	hSpCas9	negative selection	10383065
819818	819841	11	-	28162770	TF1	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	NaN	[NaN]	[342]	1	hSpCas9	negative selection	10383066
819831	819854	11	-	28162770	TF1	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	NaN	[NaN]	[185]	1	hSpCas9	negative selection	10383067
821952	821975	11	+	28162770	TF1	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	NaN	[NaN]	[370]	1	hSpCas9	negative selection	10383068
821722	821745	11	-	28162770	SKM1	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.10399772053421752	[79]	[151]	1	hSpCas9	negative selection	10552427
821981	822004	11	-	28162770	SKM1	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	-0.7253256786103319	[100]	[107]	-5	hSpCas9	negative selection	10552428
822555	822578	11	-	28162770	SKM1	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	-2.4069641987431614	[5]	[1]	-8	hSpCas9	negative selection	10552429
822592	822615	11	-	28162770	SKM1	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	0.34149703426087386	[24]	[55]	3	hSpCas9	negative selection	10552430
819808	819831	11	+	28162770	SKM1	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	-0.7981549560676379	[59]	[60]	-5	hSpCas9	negative selection	10552431
819818	819841	11	-	28162770	SKM1	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	-0.6401633750361926	[66]	[75]	-5	hSpCas9	negative selection	10552432
819831	819854	11	-	28162770	SKM1	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	0.8325017359522275	[26]	[84]	7	hSpCas9	negative selection	10552433
821952	821975	11	+	28162770	SKM1	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	0.8420323736903497	[70]	[224]	7	hSpCas9	negative selection	10552434
821722	821745	11	-	28162770	SKM1	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.10399772053421752	[79]	[151]	1	hSpCas9	negative selection	10721793
821981	822004	11	-	28162770	SKM1	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	-0.7253256786103319	[100]	[107]	-5	hSpCas9	negative selection	10721794
822555	822578	11	-	28162770	SKM1	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	-2.4069641987431614	[5]	[1]	-8	hSpCas9	negative selection	10721795
822592	822615	11	-	28162770	SKM1	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	0.34149703426087386	[24]	[55]	3	hSpCas9	negative selection	10721796
819808	819831	11	+	28162770	SKM1	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	-0.7981549560676379	[59]	[60]	-5	hSpCas9	negative selection	10721797
819818	819841	11	-	28162770	SKM1	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	-0.6401633750361926	[66]	[75]	-5	hSpCas9	negative selection	10721798
819831	819854	11	-	28162770	SKM1	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	0.8325017359522275	[26]	[84]	7	hSpCas9	negative selection	10721799
821952	821975	11	+	28162770	SKM1	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	0.8420323736903497	[70]	[224]	7	hSpCas9	negative selection	10721800
821722	821745	11	-	28162770	PL21	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.6304438704214743	[281]	[189]	5	hSpCas9	negative selection	10891159
821981	822004	11	-	28162770	PL21	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	-0.5462334329325843	[358]	[106]	-4	hSpCas9	negative selection	10891160
822555	822578	11	-	28162770	PL21	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	0.07085659754435358	[34]	[15]	0	hSpCas9	negative selection	10891161
822592	822615	11	-	28162770	PL21	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	0.7929642329834468	[121]	[91]	6	hSpCas9	negative selection	10891162
819808	819831	11	+	28162770	PL21	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	-0.42664306192646323	[209]	[67]	-3	hSpCas9	negative selection	10891163
819818	819841	11	-	28162770	PL21	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	0.36129440630390025	[219]	[122]	3	hSpCas9	negative selection	10891164
819831	819854	11	-	28162770	PL21	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	-1.700324711959765	[111]	[14]	-8	hSpCas9	negative selection	10891165
821952	821975	11	+	28162770	PL21	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	0.8410585211844921	[235]	[183]	7	hSpCas9	negative selection	10891166
821722	821745	11	-	28162770	P31FUJ	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.12229275440818291	[214]	[274]	1	hSpCas9	negative selection	11060525
821981	822004	11	-	28162770	P31FUJ	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	0.23205875592992786	[433]	[598]	2	hSpCas9	negative selection	11060526
822555	822578	11	-	28162770	P31FUJ	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	0.8984423288638741	[20]	[45]	8	hSpCas9	negative selection	11060527
822592	822615	11	-	28162770	P31FUJ	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	-0.4074807358273256	[113]	[100]	-4	hSpCas9	negative selection	11060528
819808	819831	11	+	28162770	P31FUJ	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	-0.12751330552961349	[316]	[340]	-1	hSpCas9	negative selection	11060529
819818	819841	11	-	28162770	P31FUJ	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	-0.46093099529997106	[293]	[250]	-4	hSpCas9	negative selection	11060530
819831	819854	11	-	28162770	P31FUJ	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	-0.15618092281146617	[164]	[173]	-1	hSpCas9	negative selection	11060531
821952	821975	11	+	28162770	P31FUJ	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	0.07300622510970667	[287]	[355]	0	hSpCas9	negative selection	11060532
821722	821745	11	-	28162770	OCIAML5	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.0816417504268202	[166]	[318]	0	hSpCas9	negative selection	11229891
821981	822004	11	-	28162770	OCIAML5	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	0.28410482440635165	[196]	[432]	2	hSpCas9	negative selection	11229892
822555	822578	11	-	28162770	OCIAML5	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	-1.4370290715851533	[8]	[5]	-7	hSpCas9	negative selection	11229893
822592	822615	11	-	28162770	OCIAML5	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	-0.9428320347871794	[81]	[76]	-5	hSpCas9	negative selection	11229894
819808	819831	11	+	28162770	OCIAML5	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	-0.4557656341667391	[154]	[203]	-3	hSpCas9	negative selection	11229895
819818	819841	11	-	28162770	OCIAML5	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	0.3892840081763355	[161]	[382]	3	hSpCas9	negative selection	11229896
819831	819854	11	-	28162770	OCIAML5	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	-0.6265068704488661	[64]	[75]	-4	hSpCas9	negative selection	11229897
821952	821975	11	+	28162770	OCIAML5	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	-0.060845180837370394	[166]	[288]	0	hSpCas9	negative selection	11229898
821722	821745	11	-	28162770	EOL1	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	-0.044791675727670066	[418]	[213]	0	hSpCas9	negative selection	11399257
821981	822004	11	-	28162770	EOL1	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	-0.2789856225145976	[455]	[197]	-2	hSpCas9	negative selection	11399258
822555	822578	11	-	28162770	EOL1	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	-3.0296485388163408	[30]	[1]	-9	hSpCas9	negative selection	11399259
822592	822615	11	-	28162770	EOL1	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	0.8966687389950978	[208]	[204]	7	hSpCas9	negative selection	11399260
819808	819831	11	+	28162770	EOL1	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	-0.0754522284294654	[327]	[163]	0	hSpCas9	negative selection	11399261
819818	819841	11	-	28162770	EOL1	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	-1.2858120942710163	[198]	[42]	-7	hSpCas9	negative selection	11399262
819831	819854	11	-	28162770	EOL1	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	0.8775502920333651	[155]	[150]	7	hSpCas9	negative selection	11399263
821952	821975	11	+	28162770	EOL1	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	0.17322688442725825	[302]	[179]	1	hSpCas9	negative selection	11399264
821722	821745	11	-	28162770	MOLM13	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	-0.23351502739868285	[373]	[229]	-1	hSpCas9	negative selection	11568623
821981	822004	11	-	28162770	MOLM13	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	-1.1201525121085494	[468]	[155]	-5	hSpCas9	negative selection	11568624
822555	822578	11	-	28162770	MOLM13	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	1.6523139526820065	[21]	[49]	9	hSpCas9	negative selection	11568625
822592	822615	11	-	28162770	MOLM13	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	0.9775637549614977	[117]	[167]	7	hSpCas9	negative selection	11568626
819808	819831	11	+	28162770	MOLM13	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	-0.9233707344511389	[340]	[129]	-5	hSpCas9	negative selection	11568627
819818	819841	11	-	28162770	MOLM13	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	-1.1170731191765775	[305]	[101]	-5	hSpCas9	negative selection	11568628
819831	819854	11	-	28162770	MOLM13	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	-0.37304413248780266	[162]	[90]	-2	hSpCas9	negative selection	11568629
821952	821975	11	+	28162770	MOLM13	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	-0.7447220189992838	[342]	[147]	-4	hSpCas9	negative selection	11568630
821722	821745	11	-	28162770	HEL	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.1370030224297759	[371]	[261]	1	hSpCas9	negative selection	11737989
821981	822004	11	-	28162770	HEL	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	0.390511181123146	[398]	[334]	3	hSpCas9	negative selection	11737990
822555	822578	11	-	28162770	HEL	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	1.7458323249644605	[26]	[57]	9	hSpCas9	negative selection	11737991
822592	822615	11	-	28162770	HEL	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	0.7000720070663087	[147]	[153]	6	hSpCas9	negative selection	11737992
819808	819831	11	+	28162770	HEL	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	0.6553388687799906	[227]	[229]	5	hSpCas9	negative selection	11737993
819818	819841	11	-	28162770	HEL	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	0.33981169904305053	[263]	[213]	3	hSpCas9	negative selection	11737994
819831	819854	11	-	28162770	HEL	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	-0.23696693428193133	[183]	[99]	-2	hSpCas9	negative selection	11737995
821952	821975	11	+	28162770	HEL	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	0.904987242150918	[305]	[366]	7	hSpCas9	negative selection	11737996
821722	821745	11	-	28162770	MV411	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.22378628271813006	[245]	[241]	2	hSpCas9	negative selection	11907355
821981	822004	11	-	28162770	MV411	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	-0.23889691721066497	[317]	[226]	-2	hSpCas9	negative selection	11907356
822555	822578	11	-	28162770	MV411	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	-2.1101144538353083	[40]	[7]	-8	hSpCas9	negative selection	11907357
822592	822615	11	-	28162770	MV411	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	0.12098921554183625	[142]	[130]	1	hSpCas9	negative selection	11907358
819808	819831	11	+	28162770	MV411	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	0.7821452807242357	[184]	[267]	7	hSpCas9	negative selection	11907359
819818	819841	11	-	28162770	MV411	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	0.44864464222859524	[146]	[168]	4	hSpCas9	negative selection	11907360
819831	819854	11	-	28162770	MV411	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	-0.8979928887387885	[145]	[65]	-6	hSpCas9	negative selection	11907361
821952	821975	11	+	28162770	MV411	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	-0.23598692347631867	[287]	[205]	-2	hSpCas9	negative selection	11907362
821722	821745	11	-	28162770	MONOMAC1	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	0.1480986389891339	[184]	[234]	1	hSpCas9	negative selection	12076721
821981	822004	11	-	28162770	MONOMAC1	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	0.7499818612542744	[207]	[400]	7	hSpCas9	negative selection	12076722
822555	822578	11	-	28162770	MONOMAC1	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	1.5529848999320988	[10]	[36]	9	hSpCas9	negative selection	12076723
822592	822615	11	-	28162770	MONOMAC1	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	0.05608208990915731	[72]	[86]	0	hSpCas9	negative selection	12076724
819808	819831	11	+	28162770	MONOMAC1	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	0.3601806631786984	[139]	[205]	3	hSpCas9	negative selection	12076725
819818	819841	11	-	28162770	MONOMAC1	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	-0.2781736097849593	[127]	[120]	-2	hSpCas9	negative selection	12076726
819831	819854	11	-	28162770	MONOMAC1	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	-0.5654242530395762	[70]	[54]	-5	hSpCas9	negative selection	12076727
821952	821975	11	+	28162770	MONOMAC1	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	0.008772690081290224	[149]	[172]	0	hSpCas9	negative selection	12076728
821722	821745	11	-	28162770	OCIAML2	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	-0.18238485661108755	[51]	[253]	-1	hSpCas9	negative selection	12246087
821981	822004	11	-	28162770	OCIAML2	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	-0.2655153953375488	[53]	[248]	-2	hSpCas9	negative selection	12246088
822555	822578	11	-	28162770	OCIAML2	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	-2.148701730354799	[7]	[9]	-8	hSpCas9	negative selection	12246089
822592	822615	11	-	28162770	OCIAML2	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	-0.08730118569065548	[22]	[119]	0	hSpCas9	negative selection	12246090
819808	819831	11	+	28162770	OCIAML2	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	0.06852898586587025	[31]	[185]	0	hSpCas9	negative selection	12246091
819818	819841	11	-	28162770	OCIAML2	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	0.40190926557558043	[33]	[248]	4	hSpCas9	negative selection	12246092
819831	819854	11	-	28162770	OCIAML2	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	0.3148656628517037	[18]	[130]	3	hSpCas9	negative selection	12246093
821952	821975	11	+	28162770	OCIAML2	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	0.06542307499804856	[39]	[231]	0	hSpCas9	negative selection	12246094
821722	821745	11	-	28162770	OCIAML3	viability	GGACCTTCAGCAGGAAACTGCGG	PNPLA2	ENSG00000177666	-0.8077143337943886	[68]	[118]	-6	hSpCas9	negative selection	12415453
821981	822004	11	-	28162770	OCIAML3	viability	GGATGAGCCCACAGTACACGGGG	PNPLA2	ENSG00000177666	0.6784517782988992	[88]	[429]	6	hSpCas9	negative selection	12415454
822555	822578	11	-	28162770	OCIAML3	viability	AGAGGCGGTAGAGGTTGCGCAGG	PNPLA2	ENSG00000177666	-3.1789701410453195	[5]	[1]	-9	hSpCas9	negative selection	12415455
822592	822615	11	-	28162770	OCIAML3	viability	GAGCTCACCAGGGGCTCCGGCGG	PNPLA2	ENSG00000177666	0.7279204545631992	[29]	[149]	6	hSpCas9	negative selection	12415456
819808	819831	11	+	28162770	OCIAML3	viability	CGAGCACGCGCCCTTCCTGGTGG	PNPLA2	ENSG00000177666	-0.9940947981370356	[63]	[96]	-6	hSpCas9	negative selection	12415457
819818	819841	11	-	28162770	OCIAML3	viability	GTGGCGTTGGCCACCAGGAAGGG	PNPLA2	ENSG00000177666	1.2018516428956116	[35]	[249]	8	hSpCas9	negative selection	12415458
819831	819854	11	-	28162770	OCIAML3	viability	GCCGTAGATGTGCGTGGCGTTGG	PNPLA2	ENSG00000177666	-0.8503473935839488	[42]	[71]	-6	hSpCas9	negative selection	12415459
821952	821975	11	+	28162770	OCIAML3	viability	CTGAAGGCCAATGTCTGCAGCGG	PNPLA2	ENSG00000177666	-0.21763176141442445	[51]	[134]	-2	hSpCas9	negative selection	12415460