Crispr

Gene Info

  • Species: Human (Homo sapiens)
  • GeneID: 55163
  • Symbol: PNPO
  • Description: pyridoxamine 5'-phosphate oxidase
DataSource: http://genomecrispr.dkfz.de/#!/results/PNPO

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Start The end chr strand pubmed cellline condition sequence symbol ensg log2fc rc_initial rc_final effect cas screentype index
47941783 47941806 17 + 26472758 Jiyoye viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 1.2345959266175832 [203] [361] 7 hSpCas9 negative selection 123186
47941750 47941773 17 + 26472758 Jiyoye viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 1.0098398839604883 [269] [409] 6 hSpCas9 negative selection 123187
47943400 47943423 17 - 26472758 Jiyoye viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 1.091841398840304 [190] [306] 7 hSpCas9 negative selection 123188
47944627 47944650 17 - 26472758 Jiyoye viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.1195725052699872 [169] [117] -1 hSpCas9 negative selection 123189
47944694 47944717 17 + 26472758 Jiyoye viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 4.407175381505873 [0] [15] 9 hSpCas9 negative selection 123190
47941783 47941806 17 + 26472758 KBM7 viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.3123403181613742 [1494,997] [603,816] 3 hSpCas9 negative selection 314304
47941750 47941773 17 + 26472758 KBM7 viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 0.5557923494836567 [1437,1399] [1008,961] 6 hSpCas9 negative selection 314305
47943400 47943423 17 - 26472758 KBM7 viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 0.04605900015544062 [1111,829] [425,502] 0 hSpCas9 negative selection 314306
47944627 47944650 17 - 26472758 KBM7 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 0.2581120683364873 [551,757] [233,502] 2 hSpCas9 negative selection 314307
47944694 47944717 17 + 26472758 KBM7 viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 -1.4217274121196417 [102,56] [9,16] -7 hSpCas9 negative selection 314308
47941783 47941806 17 + 26472758 Raji viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.2705848354235134 [692] [193] 2 hSpCas9 negative selection 505422
47941750 47941773 17 + 26472758 Raji viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 0.14585768318823522 [517] [132] 1 hSpCas9 negative selection 505423
47943400 47943423 17 - 26472758 Raji viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 -0.43575878965292975 [407] [69] -4 hSpCas9 negative selection 505424
47944627 47944650 17 - 26472758 Raji viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.034277613849991534 [277] [62] 0 hSpCas9 negative selection 505425
47944694 47944717 17 + 26472758 Raji viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 -0.2145445595137625 [19] [3] -2 hSpCas9 negative selection 505426
47941783 47941806 17 + 26472758 K562 viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.09901265696445871 [896] [810] 0 hSpCas9 negative selection 696540
47941750 47941773 17 + 26472758 K562 viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 0.17654939175356454 [1000] [954] 1 hSpCas9 negative selection 696541
47943400 47943423 17 - 26472758 K562 viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 0.34435233117186026 [724] [776] 2 hSpCas9 negative selection 696542
47944627 47944650 17 - 26472758 K562 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.45908822482246137 [411] [252] -3 hSpCas9 negative selection 696543
47944694 47944717 17 + 26472758 K562 viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 -2.1426043954428002 [67] [12] -7 hSpCas9 negative selection 696544
47941747 47941770 17 - 26627737 DLD1 viability TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.2388471621486068 [1125] [284,297,309] -3 hSpCas9 negative selection 798408
47941782 47941805 17 + 26627737 DLD1 viability CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 0.17206014926486224 [803] [237,297,309] 1 hSpCas9 negative selection 798409
47943358 47943381 17 - 26627737 DLD1 viability CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 0.0404461855770486 [1927] [689,748,451] 0 hSpCas9 negative selection 798410
47941747 47941770 17 - 26627737 GBM cells viability after 5 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 0.35834549352298284 [287] [198,196] 5 hSpCas9 negative selection 880723
47941782 47941805 17 + 26627737 GBM cells viability after 5 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 0.46790962720177587 [423] [294,333] 7 hSpCas9 negative selection 880724
47943358 47943381 17 - 26627737 GBM cells viability after 5 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 0.0729786066889222 [927] [540,505] 1 hSpCas9 negative selection 880725
47941747 47941770 17 - 26627737 GBM cells viability after 13 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 0.49820745680100287 [287] [196,239] 6 hSpCas9 negative selection 963038
47941782 47941805 17 + 26627737 GBM cells viability after 13 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 0.35367459352686625 [423] [363,236] 4 hSpCas9 negative selection 963039
47943358 47943381 17 - 26627737 GBM cells viability after 13 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 0.053855941103197136 [927] [611,449] 0 hSpCas9 negative selection 963040
47941747 47941770 17 - 26627737 GBM cells viability after 21 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 0.07322620769231605 [287] [161,166] 0 hSpCas9 negative selection 1045353
47941782 47941805 17 + 26627737 GBM cells viability after 21 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -0.2819715194146952 [423] [213,166] -3 hSpCas9 negative selection 1045354
47943358 47943381 17 - 26627737 GBM cells viability after 21 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.22914483583198542 [927] [438,421] -2 hSpCas9 negative selection 1045355
47941747 47941770 17 - 26627737 RPE1 viability after 9 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 0.27434092936321686 [1285] [358,651] 2 hSpCas9 negative selection 1127668
47941782 47941805 17 + 26627737 RPE1 viability after 9 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 0.8092919885833231 [1124] [583,659] 5 hSpCas9 negative selection 1127669
47943358 47943381 17 - 26627737 RPE1 viability after 9 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.20446002035760014 [3768] [765,1356] -1 hSpCas9 negative selection 1127670
47941747 47941770 17 - 26627737 RPE1 viability after 12 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 0.2860916693493232 [1285] [345,500] 2 hSpCas9 negative selection 1209983
47941782 47941805 17 + 26627737 RPE1 viability after 12 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 0.8490768064878859 [1124] [423,671] 5 hSpCas9 negative selection 1209984
47943358 47943381 17 - 26627737 RPE1 viability after 12 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.04528321554826542 [3768] [872,1095] 0 hSpCas9 negative selection 1209985
47941747 47941770 17 - 26627737 RPE1 viability after 15 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 0.39589238065392895 [1285] [610,350] 2 hSpCas9 negative selection 1292298
47941782 47941805 17 + 26627737 RPE1 viability after 15 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 0.7506116749225812 [1124] [313,748] 4 hSpCas9 negative selection 1292299
47943358 47943381 17 - 26627737 RPE1 viability after 15 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.198264376758174 [3768] [885,970] -1 hSpCas9 negative selection 1292300
47941747 47941770 17 - 26627737 RPE1 viability after 18 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.8793350858037876 [1285] [207,167] -5 hSpCas9 negative selection 1374613
47941782 47941805 17 + 26627737 RPE1 viability after 18 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 0.7084585250513985 [1124] [367,632] 4 hSpCas9 negative selection 1374614
47943358 47943381 17 - 26627737 RPE1 viability after 18 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.20453934648726957 [3768] [756,1016] -1 hSpCas9 negative selection 1374615
47941747 47941770 17 - 26627737 HeLa viability after 8 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.678250547901847 [934] [352,258,177] -6 hSpCas9 negative selection 1456928
47941782 47941805 17 + 26627737 HeLa viability after 8 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 0.3160307365368563 [578] [357,253,336] 3 hSpCas9 negative selection 1456929
47943358 47943381 17 - 26627737 HeLa viability after 8 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.6245346512503085 [1723] [483,322,640] -6 hSpCas9 negative selection 1456930
47941747 47941770 17 - 26627737 HeLa viability after 12 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.565875488450003 [934] [277,209,300] -5 hSpCas9 negative selection 1539243
47941782 47941805 17 + 26627737 HeLa viability after 12 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 0.6313882139174201 [578] [358,253,510] 5 hSpCas9 negative selection 1539244
47943358 47943381 17 - 26627737 HeLa viability after 12 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.8537212881248042 [1723] [437,384,361] -7 hSpCas9 negative selection 1539245
47941747 47941770 17 - 26627737 HeLa viability after 15 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.2738979133414873 [934] [433,156,354] -2 hSpCas9 negative selection 1621558
47941782 47941805 17 + 26627737 HeLa viability after 15 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 0.8331268925147246 [578] [472,439,339] 6 hSpCas9 negative selection 1621559
47943358 47943381 17 - 26627737 HeLa viability after 15 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.4503928434166078 [1723] [348,680,512] -4 hSpCas9 negative selection 1621560
47941747 47941770 17 - 26627737 HeLa viability after 18 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.2677855513771201 [934] [300,120,354] -2 hSpCas9 negative selection 1703873
47941782 47941805 17 + 26627737 HeLa viability after 18 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 0.8224323411844281 [578] [325,345,339] 6 hSpCas9 negative selection 1703874
47943358 47943381 17 - 26627737 HeLa viability after 18 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.4401424750862004 [1723] [233,572,512] -4 hSpCas9 negative selection 1703875
47941747 47941770 17 - 26627737 HCT116 viability after 6 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 0.5071543572816689 [1008] [111,287] 3 hSpCas9 negative selection 1786188
47941782 47941805 17 + 26627737 HCT116 viability after 6 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -0.5782977134668849 [1442] [285,77] -3 hSpCas9 negative selection 1786189
47943358 47943381 17 - 26627737 HCT116 viability after 6 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.3602616897182249 [2643] [560,192] -2 hSpCas9 negative selection 1786190
47941747 47941770 17 - 26627737 HCT116 viability after 8 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.5348767082246808 [562] [301,214,127] -6 hSpCas9 negative selection 1868503
47941782 47941805 17 + 26627737 HCT116 viability after 8 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -0.5945074580676635 [709] [229,305,240] -6 hSpCas9 negative selection 1868504
47943358 47943381 17 - 26627737 HCT116 viability after 8 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.21128099077088058 [1138] [639,519,468] -2 hSpCas9 negative selection 1868505
47941747 47941770 17 - 26627737 HCT116 viability after 9 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 0.26368026393192723 [1008] [218,405] 2 hSpCas9 negative selection 1950818
47941782 47941805 17 + 26627737 HCT116 viability after 9 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -0.5882420306580654 [1442] [429,118] -4 hSpCas9 negative selection 1950819
47943358 47943381 17 - 26627737 HCT116 viability after 9 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.10999227803740519 [2643] [766,564] 0 hSpCas9 negative selection 1950820
47941747 47941770 17 - 26627737 HCT116 viability after 12 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.48460090558813423 [562] [158,170,307] -5 hSpCas9 negative selection 2033133
47941782 47941805 17 + 26627737 HCT116 viability after 12 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -0.16570764725752696 [709] [298,296,403] -2 hSpCas9 negative selection 2033134
47943358 47943381 17 - 26627737 HCT116 viability after 12 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 0.047876026728262966 [1138] [692,585,569] 0 hSpCas9 negative selection 2033135
47941747 47941770 17 - 26627737 HCT116 viability after 15 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.9049685198364833 [562] [178,184,154] -7 hSpCas9 negative selection 2115448
47941782 47941805 17 + 26627737 HCT116 viability after 15 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -0.8438270081632525 [709] [197,335,144] -7 hSpCas9 negative selection 2115449
47943358 47943381 17 - 26627737 HCT116 viability after 15 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.1231043596153274 [1138] [654,678,475] -1 hSpCas9 negative selection 2115450
47941747 47941770 17 - 26627737 HCT116 viability after 18 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 0.033376552013294924 [562] [297,378,145] 0 hSpCas9 negative selection 2197763
47941782 47941805 17 + 26627737 HCT116 viability after 18 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -0.49398933035487036 [709] [184,277,266] -4 hSpCas9 negative selection 2197764
47943358 47943381 17 - 26627737 HCT116 viability after 18 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 0.19154369356186884 [1138] [643,626,614] 1 hSpCas9 negative selection 2197765
47941784 47941807 17 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 -0.03220160096777954 [3,3] [4,1] 0 hSpCas9 positive selection 3012297
47941798 47941821 17 - 27453484 HT29 resistance to T3SS1-dependent cytotoxicity GCGGCACCTCTCGGTCCCCGCGG PNPO ENSG00000108439 0.1266495713059927 [2,1] [4,0] 2 hSpCas9 positive selection 3012298
47944633 47944656 17 + 27453484 HT29 resistance to T3SS1-dependent cytotoxicity GCTCGCATGTTGCTGCTGAAGGG PNPO ENSG00000108439 -0.9516819577692739 [3,2] [1,0] -9 hSpCas9 positive selection 3012299
47941784 47941807 17 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.07797715695780896 [3,3] [3,1] 1 hSpCas9 positive selection 3080155
47941798 47941821 17 - 27453484 HT29 resistance to T3SS2-dependent cytotoxicity GCGGCACCTCTCGGTCCCCGCGG PNPO ENSG00000108439 -1.0269288152509217 [2,2] [0,0] -9 hSpCas9 positive selection 3080156
47944633 47944656 17 + 27453484 HT29 resistance to T3SS2-dependent cytotoxicity GCTCGCATGTTGCTGCTGAAGGG PNPO ENSG00000108439 -0.8401818811527473 [3,3] [1,0] -9 hSpCas9 positive selection 3080157
47944683 47944706 + 24336571 A375 resistance to PLX after 7 days ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.00033671839877014165 [4,5] [5,4] 0 hSpCas9 positive selection 3136588
47943358 47943381 - 24336571 A375 resistance to PLX after 7 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 0.028440589268924538 [14,12] [14,13] 1 hSpCas9 positive selection 3136590
47943372 47943395 + 24336571 A375 resistance to PLX after 7 days GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 0.012708902029165192 [8,6] [7,8] 0 hSpCas9 positive selection 3136591
47944673 47944696 - 24336571 A375 resistance to PLX after 7 days TCTCGAAGTTAGTGAAGAAGCGG PNPO ENSG00000108439 0.10158394048785158 [5,4] [4,6] 3 hSpCas9 positive selection 3136592
47944683 47944706 + 24336571 A375 resistance to PLX after 14 days ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.19401174388027953 [4,5] [1,1] -2 hSpCas9 positive selection 3194381
47943358 47943381 - 24336571 A375 resistance to PLX after 14 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.20416006319801672 [17,10] [5,5] -2 hSpCas9 positive selection 3194383
47943372 47943395 + 24336571 A375 resistance to PLX after 14 days GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.45052890270370455 [7,11] [2,2] -5 hSpCas9 positive selection 3194384
47944673 47944696 - 24336571 A375 resistance to PLX after 14 days TCTCGAAGTTAGTGAAGAAGCGG PNPO ENSG00000108439 0.12389890227068068 [2,5] [1,1] 1 hSpCas9 positive selection 3194385
47944683 47944706 + 24336571 A375 viability after 7 days ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 0.1626122307653226 [4] [4,5] 2 hSpCas9 negative selection 3252174
47943358 47943381 - 24336571 A375 viability after 7 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.02905325515735449 [14] [14,12] 0 hSpCas9 negative selection 3252176
47943372 47943395 + 24336571 A375 viability after 7 days GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.5251423390039277 [12] [8,6] -6 hSpCas9 negative selection 3252177
47944673 47944696 - 24336571 A375 viability after 7 days TCTCGAAGTTAGTGAAGAAGCGG PNPO ENSG00000108439 -0.40145354583050574 [7] [5,4] -5 hSpCas9 negative selection 3252178
47944683 47944706 + 24336571 A375 viability after 14 days ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 0.16397999839840627 [4] [4,5] 2 hSpCas9 negative selection 3309967
47943358 47943381 - 24336571 A375 viability after 14 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 0.02777709955059715 [14] [17,10] 0 hSpCas9 negative selection 3309969
47943372 47943395 + 24336571 A375 viability after 14 days GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.2544216434758821 [12] [7,11] -3 hSpCas9 negative selection 3309970
47944673 47944696 - 24336571 A375 viability after 14 days TCTCGAAGTTAGTGAAGAAGCGG PNPO ENSG00000108439 -0.6268525417634456 [7] [2,5] -6 hSpCas9 negative selection 3309971
47943340 47943363 17 + 27383988 293T resistance to West Nile virus (flavivirus) CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 3.7318647224733406 [379,379] [32,32] 9 hSpCas9 positive selection 3386584
47944627 47944650 17 - 27383988 293T resistance to West Nile virus (flavivirus) CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 0.22390320990838475 [130,130] [0,0] 1 hSpCas9 positive selection 3386585
47943372 47943395 17 + 27383988 293T resistance to West Nile virus (flavivirus) GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.47738340878000324 [212,212] [0,0] -3 hSpCas9 positive selection 3386586
47941783 47941806 17 + 26780180 HT29 viability (Avana library 4 designs) CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.667436301293553 [] [] 2 hSpCas9 negative selection 3450406
47941798 47941821 17 - 26780180 HT29 viability (Avana library 4 designs) GCGGCACCTCTCGGTCCCCGCGG PNPO ENSG00000108439 1.06645973009399 [] [] 4 hSpCas9 negative selection 3450407
47944632 47944655 17 + 26780180 HT29 viability (Avana library 4 designs) GCTCGCATGTTGCTGCTGAAGGG PNPO ENSG00000108439 0.607392699290652 [] [] 2 hSpCas9 negative selection 3450408
47941783 47941806 17 + 26780180 A375 viability (Avana lentiCRISPRv2) CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 6.02321301190437 [] [] 9 hSpCas9 negative selection 3545633
47941798 47941821 17 - 26780180 A375 viability (Avana lentiCRISPRv2) GCGGCACCTCTCGGTCCCCGCGG PNPO ENSG00000108439 5.14561025088843 [] [] 8 hSpCas9 negative selection 3545634
47944632 47944655 17 + 26780180 A375 viability (Avana lentiCRISPRv2) GCTCGCATGTTGCTGCTGAAGGG PNPO ENSG00000108439 2.55446264307525 [] [] 4 hSpCas9 negative selection 3545635
47941707 47941730 17 + 26780180 A375 viability (Avana lentiCRISPRv2) CGTTCGGGCGACCTGCCGAGTGG PNPO ENSG00000108439 4.48831459817442 [] [] 7 hSpCas9 negative selection 3545636
47941792 47941815 17 + 26780180 A375 viability (Avana lentiCRISPRv2) GAGTTACCGCGGGGACCGAGAGG PNPO ENSG00000108439 2.01056877802629 [] [] 3 hSpCas9 negative selection 3545637
47941783 47941806 17 + 26780180 A375 viability (Avana lentiGuide) CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 6.40472940346619 [] [] 5 hSpCas9 negative selection 3654292
47941798 47941821 17 - 26780180 A375 viability (Avana lentiGuide) GCGGCACCTCTCGGTCCCCGCGG PNPO ENSG00000108439 0.341991834866807 [] [] 0 hSpCas9 negative selection 3654293
47944632 47944655 17 + 26780180 A375 viability (Avana lentiGuide) GCTCGCATGTTGCTGCTGAAGGG PNPO ENSG00000108439 -0.284006443955398 [] [] 0 hSpCas9 negative selection 3654294
47941707 47941730 17 + 26780180 A375 viability (Avana lentiGuide) CGTTCGGGCGACCTGCCGAGTGG PNPO ENSG00000108439 -1.97678435981149 [] [] -3 hSpCas9 negative selection 3654295
47941792 47941815 17 + 26780180 A375 viability (Avana lentiGuide) GAGTTACCGCGGGGACCGAGAGG PNPO ENSG00000108439 8.51569137667163 [] [] 6 hSpCas9 negative selection 3654296
47941783 47941806 17 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.19555764348468513 [5] [6,5] 5 hSpCas9 positive selection 3762951
47941798 47941821 17 - 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GCGGCACCTCTCGGTCCCCGCGG PNPO ENSG00000108439 0.31875830433548236 [3] [5,4] 8 hSpCas9 positive selection 3762952
47944632 47944655 17 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GCTCGCATGTTGCTGCTGAAGGG PNPO ENSG00000108439 -0.04740135926567193 [4] [4,3] -1 hSpCas9 positive selection 3762953
47941707 47941730 17 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) CGTTCGGGCGACCTGCCGAGTGG PNPO ENSG00000108439 0.3642936538166975 [5] [7,6] 9 hSpCas9 positive selection 3762954
47941792 47941815 17 + 26780180 A375 resistance to vemurafenib (Avana lentiCRISPRv2) GAGTTACCGCGGGGACCGAGAGG PNPO ENSG00000108439 0.02159572878949187 [4] [4,4] 0 hSpCas9 positive selection 3762955
47941783 47941806 17 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.22852231661070777 [6] [6,5] 6 hSpCas9 positive selection 3871558
47941798 47941821 17 - 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GCGGCACCTCTCGGTCCCCGCGG PNPO ENSG00000108439 -0.4132008005419394 [4] [2,2] -5 hSpCas9 positive selection 3871559
47944632 47944655 17 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GCTCGCATGTTGCTGCTGAAGGG PNPO ENSG00000108439 -0.022832275826663223 [4] [4,3] 0 hSpCas9 positive selection 3871560
47941707 47941730 17 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) CGTTCGGGCGACCTGCCGAGTGG PNPO ENSG00000108439 0.1667734922535858 [6] [6,5] 4 hSpCas9 positive selection 3871561
47941792 47941815 17 + 26780180 A375 resistance to vemurafenib (Avana lentiGuide) GAGTTACCGCGGGGACCGAGAGG PNPO ENSG00000108439 0.41719048846616774 [3] [5,3] 9 hSpCas9 positive selection 3871562
47944683 47944706 17 + 26780180 A375 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 1.40653818099627 [] [] 7 hSpCas9 negative selection 3982391
47944627 47944650 17 - 26780180 A375 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 1.74260048273272 [] [] 9 hSpCas9 negative selection 3982392
47943340 47943363 17 + 26780180 A375 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.809422083105822 [] [] 3 hSpCas9 negative selection 3982393
47943372 47943395 17 + 26780180 A375 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 0.797187495604778 [] [] 3 hSpCas9 negative selection 3982394
47944683 47944706 17 + 26780180 HT29 viability (GeCKOv2 library) ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 1.7237565105194 [] [] 8 hSpCas9 negative selection 4090357
47944627 47944650 17 - 26780180 HT29 viability (GeCKOv2 library) CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 1.52489808501873 [] [] 7 hSpCas9 negative selection 4090358
47943340 47943363 17 + 26780180 HT29 viability (GeCKOv2 library) CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.690321279922194 [] [] 2 hSpCas9 negative selection 4090359
47943372 47943395 17 + 26780180 HT29 viability (GeCKOv2 library) GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 1.82537806643416 [] [] 8 hSpCas9 negative selection 4090360
47944683 47944706 17 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.8815983899589828 [2] [0,0] -9 hSpCas9 positive selection 4161623
47943358 47943381 17 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.0680529485518961 [3] [1,2] -1 hSpCas9 positive selection 4161625
47943372 47943395 17 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.4553838508064308 [3] [1,1] -8 hSpCas9 positive selection 4161626
47944673 47944696 17 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) TCTCGAAGTTAGTGAAGAAGCGG PNPO ENSG00000108439 -0.24365334497451996 [2] [1,0] -5 hSpCas9 positive selection 4161627
47944683 47944706 17 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 0.9107580098317283 [1] [4,0,0,0] 6 hSpCas9 positive selection 4225645
47943358 47943381 17 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 0.11565485263884213 [3] [1,3,0,0] 0 hSpCas9 positive selection 4225647
47943372 47943395 17 + 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.3445154473047487 [4] [0,2,1,0] -5 hSpCas9 positive selection 4225648
47944673 47944696 17 - 26780180 A375 resistance to vemurafenib (GeCKOv1 lentiGuide) TCTCGAAGTTAGTGAAGAAGCGG PNPO ENSG00000108439 0.9864201335234849 [1] [2,2,3,0] 7 hSpCas9 positive selection 4225649
47944683 47944706 17 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 0.04638020577149502 [2] [3,1] 0 hSpCas9 positive selection 4291078
47943340 47943363 17 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.23397269603275533 [4] [3,3] 5 hSpCas9 positive selection 4355327
47944627 47944650 17 - 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.38590507616529934 [3] [2,0] -7 hSpCas9 positive selection 4355328
47943372 47943395 17 + 26780180 A375 resistance to vemurafenib (GeCKOv2 lentiGuide) GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 0.2734678417596029 [3] [2,3] 5 hSpCas9 positive selection 4355329
47941784 47941806 17 + 27760321 OCIAML3 viability ATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 -0.25807917008897174 [897,756] [503,584] -3 hSpCas9 negative selection 4429044
47943341 47943363 17 + 27760321 OCIAML3 viability AGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.8473545314511697 [792,604] [754,1263] 8 hSpCas9 negative selection 4429045
47944684 47944706 17 + 27760321 OCIAML3 viability CTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -1.2828673492806137 [110,97] [36,28] -8 hSpCas9 negative selection 4429046
47941784 47941806 17 + 27760321 OCIAML2 viability ATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 -0.6674815931391401 [897,756] [412,428] -6 hSpCas9 negative selection 4512507
47943341 47943363 17 + 27760321 OCIAML2 viability AGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.3410874330852467 [792,604] [604,849] 4 hSpCas9 negative selection 4512508
47944684 47944706 17 + 27760321 OCIAML2 viability CTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 0.10905250124234023 [110,97] [68,119] 1 hSpCas9 negative selection 4512509
47941784 47941806 17 + 27760321 MV411 viability ATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 -0.12289680636055988 [897,756] [519,468] -1 hSpCas9 negative selection 4595970
47943341 47943363 17 + 27760321 MV411 viability AGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 1.4480835427448704 [792,604] [1484,893] 9 hSpCas9 negative selection 4595971
47944684 47944706 17 + 27760321 MV411 viability CTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.06501227045601699 [110,97] [66,63] 0 hSpCas9 negative selection 4595972
47941784 47941806 17 + 27760321 HL60 viability ATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.6747933789382384 [897,756] [1077,1071] 7 hSpCas9 negative selection 4679433
47943341 47943363 17 + 27760321 HL60 viability AGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 1.6205864806185155 [792,604] [1897,1576] 9 hSpCas9 negative selection 4679434
47944684 47944706 17 + 27760321 HL60 viability CTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.621934189475132 [110,97] [50,59] -6 hSpCas9 negative selection 4679435
47941784 47941806 17 + 27760321 HT1080 viability ATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.5488143397457419 [756,590] [261,535] 3 hSpCas9 negative selection 4762896
47943341 47943363 17 + 27760321 HT1080 viability AGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.9869707720522547 [604,471] [449,397] 5 hSpCas9 negative selection 4762897
47944684 47944706 17 + 27760321 HT1080 viability CTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -5.123992925797117 [97,76] [0,0] -8 hSpCas9 negative selection 4762898
47941784 47941806 17 + 27760321 HT29 viability after 7 days ATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 -0.3781712096167883 [756,590] [817,507,693] -5 hSpCas9 negative selection 4846359
47943341 47943363 17 + 27760321 HT29 viability after 7 days AGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.44056199008541164 [604,471] [755,896,1131] 6 hSpCas9 negative selection 4846360
47944684 47944706 17 + 27760321 HT29 viability after 7 days CTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.7726713577878237 [97,76] [103,33,64] -8 hSpCas9 negative selection 4846361
47941784 47941806 17 + 27760321 HT29 viability after 25 days ATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 -0.27241072129046773 [756,590] [753,503,647] -3 hSpCas9 negative selection 4929822
47943341 47943363 17 + 27760321 HT29 viability after 25 days AGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.46626795556769607 [604,471] [737,996,817] 5 hSpCas9 negative selection 4929823
47944684 47944706 17 + 27760321 HT29 viability after 25 days CTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.48954742442623456 [97,76] [78,115,11] -4 hSpCas9 negative selection 4929824
47941784 47941806 17 + 27760321 HT29 viability after 22 days ATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 -0.0738363731908882 [756,590] [1066,518,624] 0 hSpCas9 negative selection 5013285
47943341 47943363 17 + 27760321 HT29 viability after 22 days AGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.16699549217735754 [604,471] [708,733,652] 1 hSpCas9 negative selection 5013286
47944684 47944706 17 + 27760321 HT29 viability after 22 days CTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.23972164633370996 [97,76] [25,117,114] -2 hSpCas9 negative selection 5013287
47941784 47941806 17 + 27760321 HT29 viability after 19 days ATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 -0.5144305979862138 [756,590] [751,514,379] -4 hSpCas9 negative selection 5096748
47943341 47943363 17 + 27760321 HT29 viability after 19 days AGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.5209433388802196 [604,471] [1148,692,837] 5 hSpCas9 negative selection 5096749
47944684 47944706 17 + 27760321 HT29 viability after 19 days CTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.29701805363398615 [97,76] [55,164,22] -3 hSpCas9 negative selection 5096750
47941784 47941806 17 + 27760321 HT29 viability after 16 days ATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 -0.2699373238557391 [756,590] [641,536,700] -3 hSpCas9 negative selection 5180211
47943341 47943363 17 + 27760321 HT29 viability after 16 days AGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.44632496182696557 [604,471] [989,840,646] 5 hSpCas9 negative selection 5180212
47944684 47944706 17 + 27760321 HT29 viability after 16 days CTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -2.0750870420249123 [97,76] [24,18,25] -8 hSpCas9 negative selection 5180213
47941784 47941806 17 + 27760321 HT29 viability after 13 days ATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 -0.4159458743087708 [756,590] [592,440,715] -5 hSpCas9 negative selection 5263674
47943341 47943363 17 + 27760321 HT29 viability after 13 days AGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.4712726576786772 [604,471] [907,808,879] 6 hSpCas9 negative selection 5263675
47944684 47944706 17 + 27760321 HT29 viability after 13 days CTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.32153742886059256 [97,76] [148,53,42] -4 hSpCas9 negative selection 5263676
47941784 47941806 17 + 27760321 HT29 viability after 10 days ATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 -0.39359000948884426 [756,590] [640,665,615] -5 hSpCas9 negative selection 5347137
47943341 47943363 17 + 27760321 HT29 viability after 10 days AGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.3012519890101354 [604,471] [926,879,682] 4 hSpCas9 negative selection 5347138
47944684 47944706 17 + 27760321 HT29 viability after 10 days CTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.5913740913889942 [97,76] [48,110,58] -6 hSpCas9 negative selection 5347139
47941784 47941806 17 + 27760321 MOLM13 viability ATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 1.4418358832727396 [897,756] [2115,537] 8 hSpCas9 negative selection 5430600
47943341 47943363 17 + 27760321 MOLM13 viability AGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 1.1806183189487744 [792,604] [933,846] 8 hSpCas9 negative selection 5430601
47944684 47944706 17 + 27760321 MOLM13 viability CTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -1.3367846373041394 [110,97] [25,20] -6 hSpCas9 negative selection 5430602
47941888 47941911 17 + 27661255 K562 viability GGAGTAGTAGGAGCCCCTCGGGG PNPO ENSG00000108439 -0.13327077086338968 [456,462] [355,316] -4 dCas9-KRAB negative selection 5502920
47941767 47941790 17 - 27661255 K562 viability GCGCATGGGTCCCAGGTCCATGG PNPO ENSG00000108439 -0.06989943480157862 [509,628] [488,382] -3 dCas9-KRAB negative selection 5502921
47944683 47944706 17 + 27260156 BXPC3 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.008318063767332073 [390] [390,398,424,410] 0 hSpCas9 negative selection 5563538
47943340 47943363 17 + 27260156 BXPC3 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 -0.0629854123042346 [1120] [902,1071,1335,1210] -1 hSpCas9 negative selection 5627787
47944627 47944650 17 - 27260156 BXPC3 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.17999388183873324 [513] [333,428,595,566] -4 hSpCas9 negative selection 5627788
47943372 47943395 17 + 27260156 BXPC3 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.4111654539549607 [695] [495,598,475,624] -7 hSpCas9 negative selection 5627789
47944683 47944706 17 + 27260156 A673 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.21306530476779922 [390] [525,405,343,354] -5 hSpCas9 negative selection 5684789
47943340 47943363 17 + 27260156 A673 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.01717553231525959 [1120] [1690,1351,1308,1118] 0 hSpCas9 negative selection 5749038
47944627 47944650 17 - 27260156 A673 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.29143140346935553 [513] [571,498,384,572] -6 hSpCas9 negative selection 5749039
47943372 47943395 17 + 27260156 A673 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.32898378200306966 [695] [628,641,599,792] -7 hSpCas9 negative selection 5749040
47944683 47944706 17 + 27260156 A375 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.129167330947507 [390] [292,765,320,344] -2 hSpCas9 negative selection 5806040
47943340 47943363 17 + 27260156 A375 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.2576025061806586 [1120] [1568,1873,1548,1333] 4 hSpCas9 negative selection 5870289
47944627 47944650 17 - 27260156 A375 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.3918722671905741 [513] [417,566,563,311] -5 hSpCas9 negative selection 5870290
47943372 47943395 17 + 27260156 A375 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.5773291242455939 [695] [365,654,632,537] -6 hSpCas9 negative selection 5870291
47944683 47944706 17 + 27260156 COLO741 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.5441704288560805 [390] [422,327,286] -8 hSpCas9 negative selection 5927291
47943340 47943363 17 + 27260156 COLO741 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 -0.11767496646795261 [1120] [1548,1255,1181] -3 hSpCas9 negative selection 5991540
47944627 47944650 17 - 27260156 COLO741 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.5583916967171382 [513] [447,483,407] -8 hSpCas9 negative selection 5991541
47943372 47943395 17 + 27260156 COLO741 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.37413486460129053 [695] [814,725,537] -7 hSpCas9 negative selection 5991542
47944683 47944706 17 + 27260156 CAL120 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.2175960691094434 [390] [513,531,226] -3 hSpCas9 negative selection 6048542
47943340 47943363 17 + 27260156 CAL120 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.049751720991962456 [1120] [1288,1585,1432] 0 hSpCas9 negative selection 6112791
47944627 47944650 17 - 27260156 CAL120 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.22200665087426197 [513] [664,533,464] -3 hSpCas9 negative selection 6112792
47943372 47943395 17 + 27260156 CAL120 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.48742340947729385 [695] [749,561,561] -6 hSpCas9 negative selection 6112793
47944683 47944706 17 + 27260156 CADOES1 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.1464221347650861 [390] [375,320,290,325] -3 hSpCas9 negative selection 6169793
47943340 47943363 17 + 27260156 CADOES1 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.17346510101865853 [1120] [1065,1152,1267,1217] 3 hSpCas9 negative selection 6234042
47944627 47944650 17 - 27260156 CADOES1 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.8668225615208536 [513] [408,267,165,202] -9 hSpCas9 negative selection 6234043
47943372 47943395 17 + 27260156 CADOES1 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.4928386595196604 [695] [545,551,358,379] -7 hSpCas9 negative selection 6234044
47944683 47944706 17 + 27260156 EWS502 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.5093353913316392 [390] [168,368,330,306] -7 hSpCas9 negative selection 6291044
47943340 47943363 17 + 27260156 EWS502 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.06442164903902081 [1120] [960,1181,1459,1409] 1 hSpCas9 negative selection 6355293
47944627 47944650 17 - 27260156 EWS502 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.3866396814675968 [513] [231,417,498,547] -6 hSpCas9 negative selection 6355294
47943372 47943395 17 + 27260156 EWS502 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.49142357638187956 [695] [381,430,463,862] -7 hSpCas9 negative selection 6355295
47944683 47944706 17 + 27260156 EW8 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.2927228160746776 [390] [305,224,240,269] -5 hSpCas9 negative selection 6412295
47943340 47943363 17 + 27260156 EW8 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.14491330044769346 [1120] [1201,1027,862,967] 2 hSpCas9 negative selection 6476544
47944627 47944650 17 - 27260156 EW8 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.0055105062270168065 [513] [558,297,420,394] 0 hSpCas9 negative selection 6476545
47943372 47943395 17 + 27260156 EW8 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.1183507694902865 [695] [573,533,484,495] -2 hSpCas9 negative selection 6476546
47944683 47944706 17 + 27260156 CORL105 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.3148992434732711 [390] [328,393,474,288] -5 hSpCas9 negative selection 6533546
47943340 47943363 17 + 27260156 CORL105 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.15153141033608986 [1120] [1293,1599,1390,1525] 3 hSpCas9 negative selection 6597795
47944627 47944650 17 - 27260156 CORL105 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.6250577917073024 [513] [359,378,511,327] -8 hSpCas9 negative selection 6597796
47943372 47943395 17 + 27260156 CORL105 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.5108640343389446 [695] [583,614,659,441] -7 hSpCas9 negative selection 6597797
47944683 47944706 17 + 27260156 HS294T viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.19869593970638577 [390] [211,83,108,111] -3 hSpCas9 negative selection 6654797
47943340 47943363 17 + 27260156 HS294T viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.0775832876368665 [1120] [293,467,581,507] 1 hSpCas9 negative selection 6719046
47944627 47944650 17 - 27260156 HS294T viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.32134025846587133 [513] [108,213,124,196] -4 hSpCas9 negative selection 6719047
47943372 47943395 17 + 27260156 HS294T viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -1.083136736179243 [695] [114,87,140,173] -9 hSpCas9 negative selection 6719048
47944683 47944706 17 + 27260156 HCC44 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 0.251949602666029 [390] [423,801,442,374] 4 hSpCas9 negative selection 6776048
47943340 47943363 17 + 27260156 HCC44 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 -0.07550111242280444 [1120] [1571,1110,1250,932] -1 hSpCas9 negative selection 6840297
47944627 47944650 17 - 27260156 HCC44 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.29354018804396254 [513] [743,342,529,333] -5 hSpCas9 negative selection 6840298
47943372 47943395 17 + 27260156 HCC44 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.5216761792611259 [695] [490,417,940,423] -7 hSpCas9 negative selection 6840299
47944683 47944706 17 + 27260156 G402 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 0.44253724721545573 [390] [835,441,550,770] 5 hSpCas9 negative selection 6897299
47943340 47943363 17 + 27260156 G402 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.06863931566695936 [1120] [2102,1295,1476,967] 0 hSpCas9 negative selection 6961548
47944627 47944650 17 - 27260156 G402 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.09566486555449794 [513] [292,1123,451,470] -1 hSpCas9 negative selection 6961549
47943372 47943395 17 + 27260156 G402 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.7535899150996369 [695] [514,456,454,580] -7 hSpCas9 negative selection 6961550
47944683 47944706 17 + 27260156 L33 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.1982884508156026 [390] [344,200,161,269] -4 hSpCas9 negative selection 7018550
47943340 47943363 17 + 27260156 L33 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 -0.10833639029022923 [1120] [1244,460,450,1064] -2 hSpCas9 negative selection 7082799
47944627 47944650 17 - 27260156 L33 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.13042285902453848 [513] [392,234,272,478] -3 hSpCas9 negative selection 7082800
47943372 47943395 17 + 27260156 L33 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.7546515270811867 [695] [479,143,249,418] -9 hSpCas9 negative selection 7082801
47944683 47944706 17 + 27260156 K562 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.3374620706560814 [390] [326,367,254,168] -4 hSpCas9 negative selection 7139801
47943340 47943363 17 + 27260156 K562 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.21959371125388416 [1120] [951,1225,1418,1032] 2 hSpCas9 negative selection 7204050
47944627 47944650 17 - 27260156 K562 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.5655499171201421 [513] [265,348,304,309] -6 hSpCas9 negative selection 7204051
47943372 47943395 17 + 27260156 K562 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -1.0807226969885315 [695] [376,277,234,283] -8 hSpCas9 negative selection 7204052
47944683 47944706 17 + 27260156 HT29 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.16795305127127852 [390] [428,401,497,365] -3 hSpCas9 negative selection 7261052
47943340 47943363 17 + 27260156 HT29 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.10625375428858486 [1120] [1729,1396,1259,1481] 2 hSpCas9 negative selection 7325301
47944627 47944650 17 - 27260156 HT29 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.2567872677059705 [513] [550,749,378,439] -5 hSpCas9 negative selection 7325302
47943372 47943395 17 + 27260156 HT29 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.26062957108645624 [695] [788,841,690,536] -5 hSpCas9 negative selection 7325303
47944683 47944706 17 + 27260156 MHHES1 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.4619494894256159 [390] [495,339,205,264] -7 hSpCas9 negative selection 7382303
47943340 47943363 17 + 27260156 MHHES1 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.01812116179759493 [1120] [1887,1442,1102,842] 0 hSpCas9 negative selection 7446552
47944627 47944650 17 - 27260156 MHHES1 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.2755373862683349 [513] [672,555,443,301] -5 hSpCas9 negative selection 7446553
47943372 47943395 17 + 27260156 MHHES1 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.8054023231990619 [695] [339,517,421,487] -9 hSpCas9 negative selection 7446554
47944683 47944706 17 + 27260156 MEWO viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.3085449308843717 [390] [253,301,321] -6 hSpCas9 negative selection 7503554
47943340 47943363 17 + 27260156 MEWO viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.13858576664626288 [1120] [1412,1019,1080] 3 hSpCas9 negative selection 7567803
47944627 47944650 17 - 27260156 MEWO viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.16266069953794077 [513] [542,365,401] -4 hSpCas9 negative selection 7567804
47943372 47943395 17 + 27260156 MEWO viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.15064300136536107 [695] [784,396,616] -3 hSpCas9 negative selection 7567805
47944683 47944706 17 + 27260156 LNCAPCLONEFGC viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.3054960267977593 [390] [296,340,256,242] -5 hSpCas9 negative selection 7624805
47943340 47943363 17 + 27260156 LNCAPCLONEFGC viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.21557512481424412 [1120] [1129,1289,1385,933] 3 hSpCas9 negative selection 7689054
47944627 47944650 17 - 27260156 LNCAPCLONEFGC viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.3825998915928636 [513] [381,326,593,161] -5 hSpCas9 negative selection 7689055
47943372 47943395 17 + 27260156 LNCAPCLONEFGC viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.4037562270494018 [695] [469,359,477,605] -6 hSpCas9 negative selection 7689056
47944683 47944706 17 + 27260156 PANC0327 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.01081314817103074 [390] [351,355,348,320] 0 hSpCas9 negative selection 7746056
47943340 47943363 17 + 27260156 PANC0327 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 -0.03209316158450992 [1120] [833,1291,1029,686] 0 hSpCas9 negative selection 7810305
47944627 47944650 17 - 27260156 PANC0327 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.3908757559893173 [513] [414,380,301,295] -5 hSpCas9 negative selection 7810306
47943372 47943395 17 + 27260156 PANC0327 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.8219402701045511 [695] [422,231,343,420] -8 hSpCas9 negative selection 7810307
47944683 47944706 17 + 27260156 NCIH2009 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.4127632440599019 [390] [448,466,320] -5 hSpCas9 negative selection 7867307
47943340 47943363 17 + 27260156 NCIH2009 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.3795261501469014 [1120] [2037,1715,2360] 5 hSpCas9 negative selection 7931556
47944627 47944650 17 - 27260156 NCIH2009 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.419881564526977 [513] [757,437,458] -5 hSpCas9 negative selection 7931557
47943372 47943395 17 + 27260156 NCIH2009 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.7910205035601015 [695] [412,483,759] -7 hSpCas9 negative selection 7931558
47944683 47944706 17 + 27260156 NCIH1373 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 0.2590760548417483 [390] [747,533,325,137] 2 hSpCas9 negative selection 7988558
47943340 47943363 17 + 27260156 NCIH1373 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.416468489761445 [1120] [1554,1533,1747,490] 4 hSpCas9 negative selection 8052807
47944627 47944650 17 - 27260156 NCIH1373 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -1.2396106856938882 [513] [302,403,100,40] -8 hSpCas9 negative selection 8052808
47943372 47943395 17 + 27260156 NCIH1373 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.9320847945924533 [695] [348,391,489,102] -7 hSpCas9 negative selection 8052809
47944683 47944706 17 + 27260156 PATU8902 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -1.1543614649000487 [390] [226,191,283,265] -7 hSpCas9 negative selection 8109809
47943340 47943363 17 + 27260156 PATU8902 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.6398657889903878 [1120] [2367,2545,1938,3062] 6 hSpCas9 negative selection 8174058
47944627 47944650 17 - 27260156 PATU8902 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.17817935173208696 [513] [835,937,186,684] -2 hSpCas9 negative selection 8174059
47943372 47943395 17 + 27260156 PATU8902 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -1.133736233539003 [695] [447,274,325,784] -7 hSpCas9 negative selection 8174060
47944683 47944706 17 + 27260156 PANC1 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.087735010301076 [390] [256,296,414,291] -1 hSpCas9 negative selection 8231060
47943340 47943363 17 + 27260156 PANC1 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.17437014776309478 [1120] [1056,1381,1011,958] 2 hSpCas9 negative selection 8295309
47944627 47944650 17 - 27260156 PANC1 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.7666387349513359 [513] [289,246,278,220] -8 hSpCas9 negative selection 8295310
47943372 47943395 17 + 27260156 PANC1 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.8509133589252293 [695] [263,518,307,277] -8 hSpCas9 negative selection 8295311
47944683 47944706 17 + 27260156 PANC0813 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.23066049715201725 [390] [387,475,389,314] -4 hSpCas9 negative selection 8352311
47943340 47943363 17 + 27260156 PANC0813 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 -0.028947385337861897 [1120] [1807,1029,1090,1278] 0 hSpCas9 negative selection 8416560
47944627 47944650 17 - 27260156 PANC0813 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.3254052173320928 [513] [418,463,484,548] -5 hSpCas9 negative selection 8416561
47943372 47943395 17 + 27260156 PANC0813 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.41046938541801664 [695] [697,578,730,467] -6 hSpCas9 negative selection 8416562
47944683 47944706 17 + 27260156 RDES viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.6419318545052881 [390] [260,206,338,363] -8 hSpCas9 negative selection 8473562
47943340 47943363 17 + 27260156 RDES viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.2519806448182478 [1120] [1292,1380,1587,1966] 4 hSpCas9 negative selection 8537811
47944627 47944650 17 - 27260156 RDES viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.4341777324164706 [513] [366,383,515,502] -6 hSpCas9 negative selection 8537812
47943372 47943395 17 + 27260156 RDES viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.6225104301422947 [695] [459,486,576,563] -8 hSpCas9 negative selection 8537813
47944683 47944706 17 + 27260156 PC3 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 0.2850451924823613 [390] [322,549,695,425] 6 hSpCas9 negative selection 8594813
47943340 47943363 17 + 27260156 PC3 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 -0.10489726743724836 [1120] [704,922,1887,1014] -2 hSpCas9 negative selection 8659062
47944627 47944650 17 - 27260156 PC3 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.47502031892732194 [513] [277,312,438,476] -8 hSpCas9 negative selection 8659063
47943372 47943395 17 + 27260156 PC3 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.5206535305466143 [695] [343,278,1126,455] -8 hSpCas9 negative selection 8659064
47944683 47944706 17 + 27260156 PATU8988T viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.2264505346519201 [390] [385,253,187,470] -4 hSpCas9 negative selection 8716064
47943340 47943363 17 + 27260156 PATU8988T viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.08556677251170641 [1120] [1343,845,1315,1052] 1 hSpCas9 negative selection 8780313
47944627 47944650 17 - 27260156 PATU8988T viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -1.2769850766839816 [513] [104,249,313,148] -9 hSpCas9 negative selection 8780314
47943372 47943395 17 + 27260156 PATU8988T viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.8292123496464332 [695] [276,488,363,395] -8 hSpCas9 negative selection 8780315
47944683 47944706 17 + 27260156 T47D viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.29734762124278363 [390] [323,406,378,368] -6 hSpCas9 negative selection 8837315
47943340 47943363 17 + 27260156 T47D viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 -0.024020484260135255 [1120] [1322,1211,1281,1327] 0 hSpCas9 negative selection 8901564
47944627 47944650 17 - 27260156 T47D viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.4870456068159305 [513] [405,440,400,460] -7 hSpCas9 negative selection 8901565
47943372 47943395 17 + 27260156 T47D viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.6281538340933622 [695] [515,493,529,561] -8 hSpCas9 negative selection 8901566
47944683 47944706 17 + 27260156 SU8686 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.19296016017836393 [390] [311,359,320,364] -3 hSpCas9 negative selection 8958566
47943340 47943363 17 + 27260156 SU8686 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.0561801304547731 [1120] [1012,984,1270,1430] 0 hSpCas9 negative selection 9022815
47944627 47944650 17 - 27260156 SU8686 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.5086140098552081 [513] [292,308,378,483] -7 hSpCas9 negative selection 9022816
47943372 47943395 17 + 27260156 SU8686 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.6125005629250971 [695] [405,407,428,591] -7 hSpCas9 negative selection 9022817
47944683 47944706 17 + 27260156 SKES1 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 0.05269661310657153 [390] [512,469,439,233] 1 hSpCas9 negative selection 9079817
47943340 47943363 17 + 27260156 SKES1 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 -0.07658836786096357 [1120] [959,1007,1070,1158] -2 hSpCas9 negative selection 9144066
47944627 47944650 17 - 27260156 SKES1 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.2144828309686064 [513] [599,423,418,350] -5 hSpCas9 negative selection 9144067
47943372 47943395 17 + 27260156 SKES1 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.32296049291749307 [695] [506,460,664,560] -6 hSpCas9 negative selection 9144068
47944683 47944706 17 + 27260156 TOV112D viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.3594963309835785 [390] [407,336,262,230] -6 hSpCas9 negative selection 9201068
47943340 47943363 17 + 27260156 TOV112D viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.00506851972266853 [1120] [1037,1104,1146,1199] 0 hSpCas9 negative selection 9265317
47944627 47944650 17 - 27260156 TOV112D viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.31406635282697054 [513] [503,508,382,293] -6 hSpCas9 negative selection 9265318
47943372 47943395 17 + 27260156 TOV112D viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.4138700265361004 [695] [471,746,515,410] -7 hSpCas9 negative selection 9265319
47944683 47944706 17 + 27260156 TC71 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.24140909985136555 [390] [313,380,364,358] -6 hSpCas9 negative selection 9322319
47943340 47943363 17 + 27260156 TC71 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.044156278744690525 [1120] [1327,1217,1181,1226] 1 hSpCas9 negative selection 9386568
47944627 47944650 17 - 27260156 TC71 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.2555694759147647 [513] [545,461,366,472] -6 hSpCas9 negative selection 9386569
47943372 47943395 17 + 27260156 TC71 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.2431363259558959 [695] [608,579,675,656] -6 hSpCas9 negative selection 9386570
47944683 47944706 17 + 27260156 TC32 viability ACTAACTTCGAGAGTCGAAAAGG PNPO ENSG00000108439 -0.39430260874387574 [390] [346,157,370,278] -6 hSpCas9 negative selection 9443570
47943340 47943363 17 + 27260156 TC32 viability CAGTGAAACAGTTTGCTGCCTGG PNPO ENSG00000108439 0.2622374287036673 [1120] [1113,820,1815,1528] 5 hSpCas9 negative selection 9507819
47944627 47944650 17 - 27260156 TC32 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.39700727077196607 [513] [414,218,460,419] -6 hSpCas9 negative selection 9507820
47943372 47943395 17 + 27260156 TC32 viability GCTGTTCAGTGTCCTGACATAGG PNPO ENSG00000108439 -0.29722975794998735 [695] [534,386,775,493] -5 hSpCas9 negative selection 9507821
47941747 47941770 17 - 27869803 HPAFII viability after 27 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.04472331910665395 [332] [190,151,NaN] 0 hSpCas9 negative selection 9561426
47941782 47941805 17 + 27869803 HPAFII viability after 27 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -1.3547469372149763 [489] [103,97,NaN] -7 hSpCas9 negative selection 9561427
47943358 47943381 17 - 27869803 HPAFII viability after 27 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.5888791229978223 [973] [370,314,NaN] -4 hSpCas9 negative selection 9561428
47941747 47941770 17 - 27869803 HPAFII viability after 15 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.06561193549794425 [332] [587,188,NaN] 0 hSpCas9 negative selection 9643875
47941782 47941805 17 + 27869803 HPAFII viability after 15 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -0.6507699921948074 [489] [586,178,NaN] -6 hSpCas9 negative selection 9643876
47943358 47943381 17 - 27869803 HPAFII viability after 15 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.5131442662012775 [973] [1190,448,NaN] -5 hSpCas9 negative selection 9643877
47941747 47941770 17 - 27869803 ASPC1 viability after 36 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 0.8307766221063628 [1132] [699,630,755] 7 hSpCas9 negative selection 9726324
47941782 47941805 17 + 27869803 ASPC1 viability after 36 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -1.3892443190421475 [1325] [104,351,85] -8 hSpCas9 negative selection 9726325
47943358 47943381 17 - 27869803 ASPC1 viability after 36 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 0.13934173368517278 [2153] [1448,696,487] 1 hSpCas9 negative selection 9726326
47941747 47941770 17 - 27869803 PATU8988S viability after 35 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.9656465256592006 [896] [178,190,NaN] -7 hSpCas9 negative selection 9808773
47941782 47941805 17 + 27869803 PATU8988S viability after 35 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -1.7608511527539743 [980] [152,79,NaN] -8 hSpCas9 negative selection 9808774
47943358 47943381 17 - 27869803 PATU8988S viability after 35 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.7249469421645649 [2024] [464,521,NaN] -6 hSpCas9 negative selection 9808775
47941747 47941770 17 - 27869803 PATU8988S viability after 31 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.9166760202399832 [896] [137,254,NaN] -7 hSpCas9 negative selection 9891222
47941782 47941805 17 + 27869803 PATU8988S viability after 31 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -1.914509076432088 [980] [112,91,NaN] -9 hSpCas9 negative selection 9891223
47943358 47943381 17 - 27869803 PATU8988S viability after 31 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.7208080442724247 [2024] [342,676,NaN] -6 hSpCas9 negative selection 9891224
47941747 47941770 17 - 27869803 HPAFII viability after 35 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.2875262478490446 [332] [139,135,NaN] -2 hSpCas9 negative selection 9973671
47941782 47941805 17 + 27869803 HPAFII viability after 35 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -0.95076762884142 [489] [93,166,NaN] -5 hSpCas9 negative selection 9973672
47943358 47943381 17 - 27869803 HPAFII viability after 35 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.12120227418156371 [973] [450,455,NaN] 0 hSpCas9 negative selection 9973673
47941747 47941770 17 - 27869803 HPAFII viability after 31 days TGGCAGCACTGCGACCACACAGG PNPO ENSG00000108439 -0.10034193953874737 [332] [203,141,NaN] 0 hSpCas9 negative selection 10056120
47941782 47941805 17 + 27869803 HPAFII viability after 31 days CCATGCGCAAGAGTTACCGCGGG PNPO ENSG00000108439 -0.7014729510291696 [489] [70,275,NaN] -4 hSpCas9 negative selection 10056121
47943358 47943381 17 - 27869803 HPAFII viability after 31 days CTGAACAGCCTCCTCAAACCAGG PNPO ENSG00000108439 -0.48232813375931016 [973] [352,432,NaN] -3 hSpCas9 negative selection 10056122
47941783 47941806 17 + 28162770 P31FUJ viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.5692584179737123 [428] [747] 6 hSpCas9 negative selection 10213763
47941750 47941773 17 + 28162770 P31FUJ viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 -0.1728783867623207 [447] [466] -2 hSpCas9 negative selection 10213764
47943400 47943423 17 - 28162770 P31FUJ viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 0.43690249654801294 [280] [446] 5 hSpCas9 negative selection 10213765
47944627 47944650 17 - 28162770 P31FUJ viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.12272781301454594 [390] [421] -1 hSpCas9 negative selection 10213766
47944694 47944717 17 + 28162770 P31FUJ viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 -1.0807991109693287 [35] [19] -6 hSpCas9 negative selection 10213767
47941783 47941806 17 + 28162770 TF1 viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 NaN [NaN] [351] 1 hSpCas9 negative selection 10383129
47941750 47941773 17 + 28162770 TF1 viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 NaN [NaN] [517] 1 hSpCas9 negative selection 10383130
47943400 47943423 17 - 28162770 TF1 viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 NaN [NaN] [434] 1 hSpCas9 negative selection 10383131
47944627 47944650 17 - 28162770 TF1 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 NaN [NaN] [342] 1 hSpCas9 negative selection 10383132
47944694 47944717 17 + 28162770 TF1 viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 NaN [NaN] [10] 1 hSpCas9 negative selection 10383133
47941783 47941806 17 + 28162770 SKM1 viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.5193569268142584 [117] [298] 5 hSpCas9 negative selection 10552495
47941750 47941773 17 + 28162770 SKM1 viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 -0.2962784006755256 [115] [166] -3 hSpCas9 negative selection 10552496
47943400 47943423 17 - 28162770 SKM1 viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 0.5098418657304395 [86] [218] 5 hSpCas9 negative selection 10552497
47944627 47944650 17 - 28162770 SKM1 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.0564669516590286 [89] [152] 0 hSpCas9 negative selection 10552498
47944694 47944717 17 + 28162770 SKM1 viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 -0.11150831521699045 [10] [17] -1 hSpCas9 negative selection 10552499
47941783 47941806 17 + 28162770 SKM1 viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.5193569268142584 [117] [298] 5 hSpCas9 negative selection 10721861
47941750 47941773 17 + 28162770 SKM1 viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 -0.2962784006755256 [115] [166] -3 hSpCas9 negative selection 10721862
47943400 47943423 17 - 28162770 SKM1 viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 0.5098418657304395 [86] [218] 5 hSpCas9 negative selection 10721863
47944627 47944650 17 - 28162770 SKM1 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.0564669516590286 [89] [152] 0 hSpCas9 negative selection 10721864
47944694 47944717 17 + 28162770 SKM1 viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 -0.11150831521699045 [10] [17] -1 hSpCas9 negative selection 10721865
47941783 47941806 17 + 28162770 PL21 viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.01543356934048612 [465] [204] 0 hSpCas9 negative selection 10891227
47941750 47941773 17 + 28162770 PL21 viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 0.9243379125816482 [453] [374] 7 hSpCas9 negative selection 10891228
47943400 47943423 17 - 28162770 PL21 viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 -0.2743021719871191 [313] [112] -2 hSpCas9 negative selection 10891229
47944627 47944650 17 - 28162770 PL21 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 0.024881168743967008 [270] [119] 0 hSpCas9 negative selection 10891230
47944694 47944717 17 + 28162770 PL21 viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 -0.7998603855106801 [23] [5] -5 hSpCas9 negative selection 10891231
47941783 47941806 17 + 28162770 P31FUJ viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.5692584179737123 [428] [747] 6 hSpCas9 negative selection 11060593
47941750 47941773 17 + 28162770 P31FUJ viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 -0.1728783867623207 [447] [466] -2 hSpCas9 negative selection 11060594
47943400 47943423 17 - 28162770 P31FUJ viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 0.43690249654801294 [280] [446] 5 hSpCas9 negative selection 11060595
47944627 47944650 17 - 28162770 P31FUJ viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.12272781301454594 [390] [421] -1 hSpCas9 negative selection 11060596
47944694 47944717 17 + 28162770 P31FUJ viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 -1.0807991109693287 [35] [19] -6 hSpCas9 negative selection 11060597
47941783 47941806 17 + 28162770 OCIAML5 viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.14210435033380553 [247] [493] 1 hSpCas9 negative selection 11229959
47941750 47941773 17 + 28162770 OCIAML5 viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 0.17020259297703566 [224] [456] 1 hSpCas9 negative selection 11229960
47943400 47943423 17 - 28162770 OCIAML5 viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 -0.8443721790739963 [186] [187] -5 hSpCas9 negative selection 11229961
47944627 47944650 17 - 28162770 OCIAML5 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 0.6740022408035908 [149] [431] 6 hSpCas9 negative selection 11229962
47944694 47944717 17 + 28162770 OCIAML5 viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 -0.7188000400005328 [30] [33] -5 hSpCas9 negative selection 11229963
47941783 47941806 17 + 28162770 EOL1 viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.13573618857023217 [830] [480] 1 hSpCas9 negative selection 11399325
47941750 47941773 17 + 28162770 EOL1 viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 0.33346659140445833 [826] [548] 3 hSpCas9 negative selection 11399326
47943400 47943423 17 - 28162770 EOL1 viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 0.5314335878277504 [565] [430] 5 hSpCas9 negative selection 11399327
47944627 47944650 17 - 28162770 EOL1 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 0.4911676921698881 [342] [253] 4 hSpCas9 negative selection 11399328
47944694 47944717 17 + 28162770 EOL1 viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 -0.5779525689586489 [33] [11] -4 hSpCas9 negative selection 11399329
47941783 47941806 17 + 28162770 MOLM13 viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.44727910186929276 [563] [555] 3 hSpCas9 negative selection 11568691
47941750 47941773 17 + 28162770 MOLM13 viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 0.19088203315818109 [663] [547] 1 hSpCas9 negative selection 11568692
47943400 47943423 17 - 28162770 MOLM13 viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 1.5644913919254884 [360] [771] 9 hSpCas9 negative selection 11568693
47944627 47944650 17 - 28162770 MOLM13 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 0.12284922671744702 [408] [321] 0 hSpCas9 negative selection 11568694
47944694 47944717 17 + 28162770 MOLM13 viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 -2.0928255729299003 [58] [9] -7 hSpCas9 negative selection 11568695
47941783 47941806 17 + 28162770 HEL viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 1.0901978089715783 [538] [734] 8 hSpCas9 negative selection 11738057
47941750 47941773 17 + 28162770 HEL viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 0.5859616402951002 [595] [572] 5 hSpCas9 negative selection 11738058
47943400 47943423 17 - 28162770 HEL viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 0.802332469305773 [435] [486] 7 hSpCas9 negative selection 11738059
47944627 47944650 17 - 28162770 HEL viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 0.34193108353463797 [355] [288] 3 hSpCas9 negative selection 11738060
47944694 47944717 17 + 28162770 HEL viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 0.09959650697382783 [50] [34] 0 hSpCas9 negative selection 11738061
47941783 47941806 17 + 28162770 MV411 viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.6884702585945636 [329] [447] 6 hSpCas9 negative selection 11907423
47941750 47941773 17 + 28162770 MV411 viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 1.192760458162461 [362] [698] 9 hSpCas9 negative selection 11907424
47943400 47943423 17 - 28162770 MV411 viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 0.6591316069872488 [323] [430] 6 hSpCas9 negative selection 11907425
47944627 47944650 17 - 28162770 MV411 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 0.7064527471222215 [314] [432] 6 hSpCas9 negative selection 11907426
47944694 47944717 17 + 28162770 MV411 viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 0.24743755078277552 [27] [27] 2 hSpCas9 negative selection 11907427
47941783 47941806 17 + 28162770 MONOMAC1 viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.4373136806237661 [267] [415] 4 hSpCas9 negative selection 12076789
47941750 47941773 17 + 28162770 MONOMAC1 viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 0.06353351882275904 [292] [350] 0 hSpCas9 negative selection 12076790
47943400 47943423 17 - 28162770 MONOMAC1 viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 -0.3151414464493125 [228] [210] -3 hSpCas9 negative selection 12076791
47944627 47944650 17 - 28162770 MONOMAC1 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 -0.4222117090673286 [172] [147] -4 hSpCas9 negative selection 12076792
47944694 47944717 17 + 28162770 MONOMAC1 viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 0.5399287471066527 [8] [14] 5 hSpCas9 negative selection 12076793
47941783 47941806 17 + 28162770 OCIAML2 viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.9054317067786797 [67] [705] 8 hSpCas9 negative selection 12246155
47941750 47941773 17 + 28162770 OCIAML2 viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 0.46865876076879487 [90] [697] 4 hSpCas9 negative selection 12246156
47943400 47943423 17 - 28162770 OCIAML2 viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 0.592170961773909 [58] [492] 6 hSpCas9 negative selection 12246157
47944627 47944650 17 - 28162770 OCIAML2 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 0.11913366174281614 [49] [300] 1 hSpCas9 negative selection 12246158
47944694 47944717 17 + 28162770 OCIAML2 viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 0.11433267547899506 [3] [23] 1 hSpCas9 negative selection 12246159
47941783 47941806 17 + 28162770 OCIAML3 viability CATGCGCAAGAGTTACCGCGGGG PNPO ENSG00000108439 0.6960950087078013 [109] [537] 6 hSpCas9 negative selection 12415521
47941750 47941773 17 + 28162770 OCIAML3 viability GTGTGGTCGCAGTGCTGCCATGG PNPO ENSG00000108439 1.9308605132334749 [95] [1104] 9 hSpCas9 negative selection 12415522
47943400 47943423 17 - 28162770 OCIAML3 viability GGTAGCCAGACACATGGCATTGG PNPO ENSG00000108439 0.2505986770300128 [70] [254] 2 hSpCas9 negative selection 12415523
47944627 47944650 17 - 28162770 OCIAML3 viability CAGCAGCAACATGCGAGCAGAGG PNPO ENSG00000108439 0.6690267655096306 [94] [455] 6 hSpCas9 negative selection 12415524
47944694 47944717 17 + 28162770 OCIAML3 viability GAGTCGAAAAGGAAAAGAGCTGG PNPO ENSG00000108439 0.8389517669519431 [4] [26] 7 hSpCas9 negative selection 12415525