Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5428
• Symbol: POLG
• Description: DNA polymerase gamma, catalytic subunit

DataSource: http://genomecrispr.dkfz.de/#!/results/POLG

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
89333298	89333321	15	-	26472758	Jiyoye	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-2.494816414689806	[440]	[58]	-9	hSpCas9	negative selection	123460
89326691	89326714	15	-	26472758	Jiyoye	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	0.06613846367080622	[18]	[14]	0	hSpCas9	negative selection	123461
89333457	89333480	15	-	26472758	Jiyoye	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	0.007905198085346121	[90]	[68]	0	hSpCas9	negative selection	123462
89333351	89333374	15	+	26472758	Jiyoye	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	-0.07571520995541303	[340]	[243]	0	hSpCas9	negative selection	123463
89330178	89330201	15	+	26472758	Jiyoye	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	0.30664850555190903	[103]	[96]	2	hSpCas9	negative selection	123464
89329045	89329068	15	+	26472758	Jiyoye	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	0.5931258068742611	[188]	[214]	4	hSpCas9	negative selection	123465
89328942	89328965	15	-	26472758	Jiyoye	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-0.414826316516132	[98]	[55]	-3	hSpCas9	negative selection	123466
89328761	89328784	15	-	26472758	Jiyoye	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-1.9246681822465717	[145]	[28]	-8	hSpCas9	negative selection	123467
89327229	89327252	15	-	26472758	Jiyoye	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-1.4859094145776148	[25]	[6]	-7	hSpCas9	negative selection	123468
89327045	89327068	15	-	26472758	Jiyoye	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	0.6136262589732997	[38]	[44]	4	hSpCas9	negative selection	123469
89333298	89333321	15	-	26472758	KBM7	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-3.4078159627372777	[1827,1278]	[78,57]	-9	hSpCas9	negative selection	314578
89326691	89326714	15	-	26472758	KBM7	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	-0.3971932285380624	[229,207]	[74,80]	-4	hSpCas9	negative selection	314579
89333457	89333480	15	-	26472758	KBM7	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	0.22805101011666395	[196,135]	[157,29]	2	hSpCas9	negative selection	314580
89333351	89333374	15	+	26472758	KBM7	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	0.16224309720539276	[1011,743]	[626,304]	1	hSpCas9	negative selection	314581
89330178	89330201	15	+	26472758	KBM7	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-0.9982402472951272	[887,628]	[151,197]	-6	hSpCas9	negative selection	314582
89329045	89329068	15	+	26472758	KBM7	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-1.9863246624082902	[1173,1189]	[177,107]	-8	hSpCas9	negative selection	314583
89328942	89328965	15	-	26472758	KBM7	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-0.6197621532610019	[503,371]	[139,125]	-5	hSpCas9	negative selection	314584
89328761	89328784	15	-	26472758	KBM7	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-0.6556611880031419	[415,521]	[136,146]	-5	hSpCas9	negative selection	314585
89327229	89327252	15	-	26472758	KBM7	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-5.386846787227908	[185,84]	[1,0]	-9	hSpCas9	negative selection	314586
89327045	89327068	15	-	26472758	KBM7	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-2.318099491770097	[443,292]	[58,11]	-9	hSpCas9	negative selection	314587
89333298	89333321	15	-	26472758	Raji	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-2.10639575565814	[834]	[44]	-8	hSpCas9	negative selection	505696
89326691	89326714	15	-	26472758	Raji	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	0.34839163487739455	[131]	[38]	3	hSpCas9	negative selection	505697
89333457	89333480	15	-	26472758	Raji	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	0.07881438317682865	[101]	[24]	0	hSpCas9	negative selection	505698
89333351	89333374	15	+	26472758	Raji	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	-0.05641015619900247	[586]	[130]	0	hSpCas9	negative selection	505699
89330178	89330201	15	+	26472758	Raji	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-0.8575126636704846	[405]	[51]	-6	hSpCas9	negative selection	505700
89329045	89329068	15	+	26472758	Raji	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-0.5606832079929999	[660]	[103]	-4	hSpCas9	negative selection	505701
89328942	89328965	15	-	26472758	Raji	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-0.5485007512781741	[270]	[42]	-4	hSpCas9	negative selection	505702
89328761	89328784	15	-	26472758	Raji	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-0.2830759411845784	[193]	[36]	-2	hSpCas9	negative selection	505703
89327229	89327252	15	-	26472758	Raji	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	0.5224210346524432	[17]	[5]	5	hSpCas9	negative selection	505704
89327045	89327068	15	-	26472758	Raji	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-0.11249328804406555	[190]	[40]	-1	hSpCas9	negative selection	505705
89333298	89333321	15	-	26472758	K562	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-4.7773490874157885	[1201]	[36]	-9	hSpCas9	negative selection	696814
89326691	89326714	15	-	26472758	K562	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	0.2102030123285339	[127]	[124]	1	hSpCas9	negative selection	696815
89333457	89333480	15	-	26472758	K562	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	-1.0739427522007232	[201]	[80]	-5	hSpCas9	negative selection	696816
89333351	89333374	15	+	26472758	K562	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	0.8288065639542377	[836]	[1254]	7	hSpCas9	negative selection	696817
89330178	89330201	15	+	26472758	K562	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-2.117835767107818	[652]	[126]	-7	hSpCas9	negative selection	696818
89329045	89329068	15	+	26472758	K562	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-0.8345151562463788	[1032]	[488]	-5	hSpCas9	negative selection	696819
89328942	89328965	15	-	26472758	K562	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-0.6556827022794326	[264]	[141]	-4	hSpCas9	negative selection	696820
89328761	89328784	15	-	26472758	K562	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-0.953520649945462	[350]	[152]	-5	hSpCas9	negative selection	696821
89327229	89327252	15	-	26472758	K562	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-1.80288698711191	[61]	[14]	-7	hSpCas9	negative selection	696822
89327045	89327068	15	-	26472758	K562	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-1.250345964083131	[216]	[76]	-6	hSpCas9	negative selection	696823
89327213	89327236	15	+	26627737	DLD1	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-1.8604086705455447	[228]	[18,1,34]	-8	hSpCas9	negative selection	792255
89328511	89328534	15	-	26627737	DLD1	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-5.12455301317323	[649]	[15,0,0]	-9	hSpCas9	negative selection	792256
89328757	89328780	15	-	26627737	DLD1	viability	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-3.681043303058413	[842]	[40,0,18]	-9	hSpCas9	negative selection	792257
89328942	89328965	15	-	26627737	DLD1	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-0.8388809939748705	[106]	[1,1,46]	-7	hSpCas9	negative selection	792258
89330239	89330262	15	+	26627737	DLD1	viability	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-0.9054977536940456	[359]	[71,2,96]	-7	hSpCas9	negative selection	792259
89333479	89333502	15	-	26627737	DLD1	viability	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-2.628698997778983	[540]	[1,40,37]	-9	hSpCas9	negative selection	792260
89327213	89327236	15	+	26627737	GBM cells	viability after 5 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	0.5663385357988148	[135]	[110,104]	7	hSpCas9	negative selection	874570
89328511	89328534	15	-	26627737	GBM cells	viability after 5 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.7128902380541118	[216]	[69,71]	-8	hSpCas9	negative selection	874571
89328757	89328780	15	-	26627737	GBM cells	viability after 5 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-0.18623424380311293	[505]	[225,250]	-3	hSpCas9	negative selection	874572
89328942	89328965	15	-	26627737	GBM cells	viability after 5 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-0.6387429110571141	[89]	[29,31]	-7	hSpCas9	negative selection	874573
89330239	89330262	15	+	26627737	GBM cells	viability after 5 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	0.9932412574338383	[36]	[44,33]	9	hSpCas9	negative selection	874574
89333479	89333502	15	-	26627737	GBM cells	viability after 5 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	0.630717763936113	[223]	[188,182]	8	hSpCas9	negative selection	874575
89327213	89327236	15	+	26627737	GBM cells	viability after 13 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.8132948896658839	[135]	[25,54]	-7	hSpCas9	negative selection	956885
89328511	89328534	15	-	26627737	GBM cells	viability after 13 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-1.2216568081591148	[216]	[55,45]	-8	hSpCas9	negative selection	956886
89328757	89328780	15	-	26627737	GBM cells	viability after 13 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-0.8477381738524411	[505]	[151,152]	-7	hSpCas9	negative selection	956887
89328942	89328965	15	-	26627737	GBM cells	viability after 13 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.3048953912228065	[89]	[32,8]	-8	hSpCas9	negative selection	956888
89330239	89330262	15	+	26627737	GBM cells	viability after 13 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-0.819555601851806	[36]	[1,18]	-7	hSpCas9	negative selection	956889
89333479	89333502	15	-	26627737	GBM cells	viability after 13 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	0.6275867919029909	[223]	[216,163]	7	hSpCas9	negative selection	956890
89327213	89327236	15	+	26627737	GBM cells	viability after 21 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.7394428736001696	[135]	[49,38]	-6	hSpCas9	negative selection	1039200
89328511	89328534	15	-	26627737	GBM cells	viability after 21 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-1.2860397276179663	[216]	[51,44]	-8	hSpCas9	negative selection	1039201
89328757	89328780	15	-	26627737	GBM cells	viability after 21 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-0.93328061861314	[505]	[144,142]	-7	hSpCas9	negative selection	1039202
89328942	89328965	15	-	26627737	GBM cells	viability after 21 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.4915259512237105	[89]	[19,14]	-8	hSpCas9	negative selection	1039203
89330239	89330262	15	+	26627737	GBM cells	viability after 21 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-0.40956217433089526	[36]	[11,17]	-4	hSpCas9	negative selection	1039204
89333479	89333502	15	-	26627737	GBM cells	viability after 21 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-0.508894186805266	[223]	[84,85]	-4	hSpCas9	negative selection	1039205
89327213	89327236	15	+	26627737	RPE1	viability after 9 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.15510836402130163	[606]	[64,306]	-1	hSpCas9	negative selection	1121515
89328511	89328534	15	-	26627737	RPE1	viability after 9 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	0.565460642127879	[292]	[102,177]	4	hSpCas9	negative selection	1121516
89328757	89328780	15	-	26627737	RPE1	viability after 9 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-0.6419781853093788	[1783]	[315,411]	-4	hSpCas9	negative selection	1121517
89328942	89328965	15	-	26627737	RPE1	viability after 9 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-2.170314665012856	[177]	[14,8]	-9	hSpCas9	negative selection	1121518
89330239	89330262	15	+	26627737	RPE1	viability after 9 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	0.2501258093159979	[38]	[24,0]	1	hSpCas9	negative selection	1121519
89333479	89333502	15	-	26627737	RPE1	viability after 9 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-1.307786428106515	[893]	[78,156]	-7	hSpCas9	negative selection	1121520
89327213	89327236	15	+	26627737	RPE1	viability after 12 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.6133776667107307	[606]	[109,102]	-4	hSpCas9	negative selection	1203830
89328511	89328534	15	-	26627737	RPE1	viability after 12 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	0.5913147569095315	[292]	[70,168]	4	hSpCas9	negative selection	1203831
89328757	89328780	15	-	26627737	RPE1	viability after 12 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-0.8682223590157366	[1783]	[349,169]	-5	hSpCas9	negative selection	1203832
89328942	89328965	15	-	26627737	RPE1	viability after 12 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-0.5265106828336976	[177]	[56,7]	-4	hSpCas9	negative selection	1203833
89330239	89330262	15	+	26627737	RPE1	viability after 12 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	0.9449505491371033	[38]	[25,13]	6	hSpCas9	negative selection	1203834
89333479	89333502	15	-	26627737	RPE1	viability after 12 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-1.005256899524338	[893]	[107,131]	-6	hSpCas9	negative selection	1203835
89327213	89327236	15	+	26627737	RPE1	viability after 15 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.7634610034648612	[606]	[148,54]	-5	hSpCas9	negative selection	1286145
89328511	89328534	15	-	26627737	RPE1	viability after 15 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	0.6193985337141259	[292]	[136,117]	4	hSpCas9	negative selection	1286146
89328757	89328780	15	-	26627737	RPE1	viability after 15 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-1.2151801346023143	[1783]	[224,209]	-6	hSpCas9	negative selection	1286147
89328942	89328965	15	-	26627737	RPE1	viability after 15 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-2.0931589622548574	[177]	[22,0]	-8	hSpCas9	negative selection	1286148
89330239	89330262	15	+	26627737	RPE1	viability after 15 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-3.4636533449903544	[38]	[0,0]	-9	hSpCas9	negative selection	1286149
89333479	89333502	15	-	26627737	RPE1	viability after 15 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-0.8246579844730295	[893]	[210,76]	-5	hSpCas9	negative selection	1286150
89327213	89327236	15	+	26627737	RPE1	viability after 18 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-2.401467590779346	[606]	[1,61]	-8	hSpCas9	negative selection	1368460
89328511	89328534	15	-	26627737	RPE1	viability after 18 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	0.646403300230929	[292]	[116,130]	4	hSpCas9	negative selection	1368461
89328757	89328780	15	-	26627737	RPE1	viability after 18 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-2.2725126484968783	[1783]	[132,63]	-8	hSpCas9	negative selection	1368462
89328942	89328965	15	-	26627737	RPE1	viability after 18 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.1520299047150857	[177]	[24,17]	-6	hSpCas9	negative selection	1368463
89330239	89330262	15	+	26627737	RPE1	viability after 18 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	0.21688127862527917	[38]	[18,4]	1	hSpCas9	negative selection	1368464
89333479	89333502	15	-	26627737	RPE1	viability after 18 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-1.329429039023025	[893]	[66,126]	-7	hSpCas9	negative selection	1368465
89327213	89327236	15	+	26627737	HeLa	viability after 8 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	1.3143437654020367	[107]	[326,43,31]	8	hSpCas9	negative selection	1450775
89328511	89328534	15	-	26627737	HeLa	viability after 8 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.8635418304321858	[350]	[163,88,20]	-7	hSpCas9	negative selection	1450776
89328757	89328780	15	-	26627737	HeLa	viability after 8 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-0.42501834241996983	[908]	[280,292,305]	-4	hSpCas9	negative selection	1450777
89328942	89328965	15	-	26627737	HeLa	viability after 8 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	0.4712739294597288	[83]	[123,5,38]	4	hSpCas9	negative selection	1450778
89330239	89330262	15	+	26627737	HeLa	viability after 8 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-0.1851122844109394	[80]	[88,3,13]	-2	hSpCas9	negative selection	1450779
89333479	89333502	15	-	26627737	HeLa	viability after 8 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	1.237658170873263	[142]	[114,108,204]	8	hSpCas9	negative selection	1450780
89327213	89327236	15	+	26627737	HeLa	viability after 12 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	0.07023094787634565	[107]	[6,97,28]	0	hSpCas9	negative selection	1533090
89328511	89328534	15	-	26627737	HeLa	viability after 12 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.4905159278372547	[350]	[108,158,35]	-4	hSpCas9	negative selection	1533091
89328757	89328780	15	-	26627737	HeLa	viability after 12 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	0.040615682215145776	[908]	[301,392,460]	0	hSpCas9	negative selection	1533092
89328942	89328965	15	-	26627737	HeLa	viability after 12 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	0.44919085535545555	[83]	[58,23,61]	4	hSpCas9	negative selection	1533093
89330239	89330262	15	+	26627737	HeLa	viability after 12 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-0.1886404914125137	[80]	[34,31,20]	-2	hSpCas9	negative selection	1533094
89333479	89333502	15	-	26627737	HeLa	viability after 12 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	1.4732266387009365	[142]	[329,107,64]	8	hSpCas9	negative selection	1533095
89327213	89327236	15	+	26627737	HeLa	viability after 15 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-1.8219944846437146	[107]	[2,2,32]	-9	hSpCas9	negative selection	1615405
89328511	89328534	15	-	26627737	HeLa	viability after 15 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.46880403723147973	[350]	[239,36,24]	-4	hSpCas9	negative selection	1615406
89328757	89328780	15	-	26627737	HeLa	viability after 15 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-1.2641885906611152	[908]	[109,207,143]	-8	hSpCas9	negative selection	1615407
89328942	89328965	15	-	26627737	HeLa	viability after 15 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	1.0985706235004318	[83]	[132,59,21]	7	hSpCas9	negative selection	1615408
89330239	89330262	15	+	26627737	HeLa	viability after 15 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-0.0022687116345454506	[80]	[26,24,47]	0	hSpCas9	negative selection	1615409
89333479	89333502	15	-	26627737	HeLa	viability after 15 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	0.6280030658828056	[142]	[172,27,65]	5	hSpCas9	negative selection	1615410
89327213	89327236	15	+	26627737	HeLa	viability after 18 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-1.798341610738797	[107]	[1,2,32]	-9	hSpCas9	negative selection	1697720
89328511	89328534	15	-	26627737	HeLa	viability after 18 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.42314225204035855	[350]	[167,29,24]	-4	hSpCas9	negative selection	1697721
89328757	89328780	15	-	26627737	HeLa	viability after 18 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-1.2776821842847454	[908]	[71,170,143]	-8	hSpCas9	negative selection	1697722
89328942	89328965	15	-	26627737	HeLa	viability after 18 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	1.1756380792477596	[83]	[91,55,21]	8	hSpCas9	negative selection	1697723
89330239	89330262	15	+	26627737	HeLa	viability after 18 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-0.03592327657053085	[80]	[17,18,47]	0	hSpCas9	negative selection	1697724
89333479	89333502	15	-	26627737	HeLa	viability after 18 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	0.657176455651315	[142]	[118,23,65]	5	hSpCas9	negative selection	1697725
89327213	89327236	15	+	26627737	HCT116	viability after 6 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	0.6826920735727184	[492]	[242,58]	4	hSpCas9	negative selection	1780035
89328511	89328534	15	-	26627737	HCT116	viability after 6 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	1.6573157142228787	[291]	[31,206]	8	hSpCas9	negative selection	1780036
89328757	89328780	15	-	26627737	HCT116	viability after 6 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-1.0077426496569868	[1467]	[282,21]	-5	hSpCas9	negative selection	1780037
89328942	89328965	15	-	26627737	HCT116	viability after 6 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	1.8490732620699706	[132]	[113,53]	8	hSpCas9	negative selection	1780038
89330239	89330262	15	+	26627737	HCT116	viability after 6 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	0.9428202906394285	[147]	[94,16]	5	hSpCas9	negative selection	1780039
89333479	89333502	15	-	26627737	HCT116	viability after 6 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-0.615600073064229	[532]	[64,48]	-4	hSpCas9	negative selection	1780040
89327213	89327236	15	+	26627737	HCT116	viability after 8 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-1.2751958129410974	[370]	[102,88,61]	-9	hSpCas9	negative selection	1862350
89328511	89328534	15	-	26627737	HCT116	viability after 8 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	1.3500000707471718	[51]	[38,63,114]	9	hSpCas9	negative selection	1862351
89328757	89328780	15	-	26627737	HCT116	viability after 8 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	0.026689584941808953	[574]	[400,355,213]	0	hSpCas9	negative selection	1862352
89328942	89328965	15	-	26627737	HCT116	viability after 8 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-0.4396656927031779	[148]	[60,91,28]	-5	hSpCas9	negative selection	1862353
89330239	89330262	15	+	26627737	HCT116	viability after 8 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-1.2963498363374573	[114]	[55,0,20]	-9	hSpCas9	negative selection	1862354
89333479	89333502	15	-	26627737	HCT116	viability after 8 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	0.1516611836004711	[444]	[417,148,252]	1	hSpCas9	negative selection	1862355
89327213	89327236	15	+	26627737	HCT116	viability after 9 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-1.7701271266242933	[492]	[51,27]	-8	hSpCas9	negative selection	1944665
89328511	89328534	15	-	26627737	HCT116	viability after 9 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	0.9262862201604316	[291]	[260,58]	6	hSpCas9	negative selection	1944666
89328757	89328780	15	-	26627737	HCT116	viability after 9 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-0.5640623860120929	[1467]	[363,186]	-4	hSpCas9	negative selection	1944667
89328942	89328965	15	-	26627737	HCT116	viability after 9 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	0.6317758562990246	[132]	[111,9]	4	hSpCas9	negative selection	1944668
89330239	89330262	15	+	26627737	HCT116	viability after 9 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	1.2836095158194594	[147]	[36,142]	8	hSpCas9	negative selection	1944669
89333479	89333502	15	-	26627737	HCT116	viability after 9 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-0.12773762080868237	[532]	[184,86]	-1	hSpCas9	negative selection	1944670
89327213	89327236	15	+	26627737	HCT116	viability after 12 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-1.3023968787618512	[370]	[104,42,85]	-8	hSpCas9	negative selection	2026980
89328511	89328534	15	-	26627737	HCT116	viability after 12 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	0.5945106841902528	[51]	[30,53,39]	5	hSpCas9	negative selection	2026981
89328757	89328780	15	-	26627737	HCT116	viability after 12 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-0.24359358049707736	[574]	[292,280,188]	-3	hSpCas9	negative selection	2026982
89328942	89328965	15	-	26627737	HCT116	viability after 12 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-2.31674445757188	[148]	[19,24,1]	-9	hSpCas9	negative selection	2026983
89330239	89330262	15	+	26627737	HCT116	viability after 12 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-2.293399692182537	[114]	[3,23,9]	-9	hSpCas9	negative selection	2026984
89333479	89333502	15	-	26627737	HCT116	viability after 12 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-1.362724629362241	[444]	[105,70,93]	-8	hSpCas9	negative selection	2026985
89327213	89327236	15	+	26627737	HCT116	viability after 15 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-2.010013534660855	[370]	[37,75,42]	-9	hSpCas9	negative selection	2109295
89328511	89328534	15	-	26627737	HCT116	viability after 15 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	0.5758874935368148	[51]	[36,81,13]	5	hSpCas9	negative selection	2109296
89328757	89328780	15	-	26627737	HCT116	viability after 15 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-0.4624935059948236	[574]	[435,162,144]	-5	hSpCas9	negative selection	2109297
89328942	89328965	15	-	26627737	HCT116	viability after 15 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.281988811642325	[148]	[69,20,18]	-8	hSpCas9	negative selection	2109298
89330239	89330262	15	+	26627737	HCT116	viability after 15 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-2.149034504308916	[114]	[16,18,8]	-9	hSpCas9	negative selection	2109299
89333479	89333502	15	-	26627737	HCT116	viability after 15 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-1.3795805465483406	[444]	[56,80,150]	-8	hSpCas9	negative selection	2109300
89327213	89327236	15	+	26627737	HCT116	viability after 18 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-2.578061110675919	[370]	[36,10,43]	-9	hSpCas9	negative selection	2191610
89328511	89328534	15	-	26627737	HCT116	viability after 18 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.5327178856393702	[51]	[42,7,0]	-5	hSpCas9	negative selection	2191611
89328757	89328780	15	-	26627737	HCT116	viability after 18 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-0.5794773515785091	[574]	[241,120,199]	-5	hSpCas9	negative selection	2191612
89328942	89328965	15	-	26627737	HCT116	viability after 18 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-2.612855071323203	[148]	[23,0,10]	-9	hSpCas9	negative selection	2191613
89330239	89330262	15	+	26627737	HCT116	viability after 18 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-2.8666461393794647	[114]	[20,0,0]	-9	hSpCas9	negative selection	2191614
89333479	89333502	15	-	26627737	HCT116	viability after 18 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-2.089621708480672	[444]	[44,23,85]	-9	hSpCas9	negative selection	2191615
89333509	89333532	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACATCCAGATGCTCTCGAGAGGG	POLG	ENSG00000140521	-1.0717514485254889	[4,4]	[2,0]	-9	hSpCas9	positive selection	3012404
89328451	89328474	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCACCTCTCCAAGAAGAGCGG	POLG	ENSG00000140521	-1.1826906215528536	[5,4]	[1,0]	-9	hSpCas9	positive selection	3012405
89333181	89333204	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTACCCGTGGCCATCCCCGAGG	POLG	ENSG00000140521	-0.6301217078931263	[3,3]	[1,1]	-7	hSpCas9	positive selection	3012406
89333457	89333480	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	-0.5547499534328321	[3,2]	[2,0]	-7	hSpCas9	positive selection	3012407
89333509	89333532	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACATCCAGATGCTCTCGAGAGGG	POLG	ENSG00000140521	-0.3815851650419563	[4,4]	[1,2]	-5	hSpCas9	positive selection	3080262
89328451	89328474	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCACCTCTCCAAGAAGAGCGG	POLG	ENSG00000140521	-1.1015468968187783	[5,5]	[2,0]	-9	hSpCas9	positive selection	3080263
89333181	89333204	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTACCCGTGGCCATCCCCGAGG	POLG	ENSG00000140521	-0.16494531064265802	[3,3]	[2,1]	-2	hSpCas9	positive selection	3080264
89333457	89333480	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	-0.4868737057798802	[3,3]	[2,0]	-7	hSpCas9	positive selection	3080265
89328716	89328739		+	24336571	A375	resistance to PLX after 7 days	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.10388626313350824	[8,7]	[7,7]	-3	hSpCas9	positive selection	3136696
89328511	89328534		+	24336571	A375	resistance to PLX after 7 days	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.23850588297810654	[15,17]	[18,20]	7	hSpCas9	positive selection	3136697
89328684	89328707		-	24336571	A375	resistance to PLX after 7 days	GGACATTCGTGAGAACTTCCAGG	POLG	ENSG00000140521	0.04885316248977134	[9,6]	[8,8]	1	hSpCas9	positive selection	3136698
89328716	89328739		+	24336571	A375	resistance to PLX after 14 days	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	0.013607469063536604	[5,4]	[1,2]	0	hSpCas9	positive selection	3194489
89328511	89328534		+	24336571	A375	resistance to PLX after 14 days	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.16793881167403046	[16,18]	[7,6]	-2	hSpCas9	positive selection	3194490
89328684	89328707		-	24336571	A375	resistance to PLX after 14 days	GGACATTCGTGAGAACTTCCAGG	POLG	ENSG00000140521	0.04254630297283912	[7,8]	[2,3]	0	hSpCas9	positive selection	3194491
89328716	89328739		+	24336571	A375	viability after 7 days	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.4429442962782463	[12]	[8,7]	-6	hSpCas9	negative selection	3252282
89328511	89328534		+	24336571	A375	viability after 7 days	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.35440684513778065	[13]	[15,17]	5	hSpCas9	negative selection	3252283
89328684	89328707		-	24336571	A375	viability after 7 days	GGACATTCGTGAGAACTTCCAGG	POLG	ENSG00000140521	-0.04136136421966774	[8]	[9,6]	0	hSpCas9	negative selection	3252284
89328716	89328739		+	24336571	A375	viability after 14 days	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.9818165340999127	[12]	[5,4]	-8	hSpCas9	negative selection	3310075
89328511	89328534		+	24336571	A375	viability after 14 days	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.5104361399056199	[13]	[16,18]	6	hSpCas9	negative selection	3310076
89328684	89328707		-	24336571	A375	viability after 14 days	GGACATTCGTGAGAACTTCCAGG	POLG	ENSG00000140521	-0.0736102746290912	[8]	[7,8]	-1	hSpCas9	negative selection	3310077
89328716	89328739	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	0.23495839841738073	[129,129]	[0,0]	1	hSpCas9	positive selection	3386665
89328511	89328534	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-1.9175994710548439	[577,577]	[0,0]	-9	hSpCas9	positive selection	3386666
89328511	89328534	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-1.1980010088587256	[350,350]	[0,0]	-7	hSpCas9	positive selection	3386667
89333509	89333532	15	-	26780180	HT29	viability (Avana library 4 designs)	ACATCCAGATGCTCTCGAGAGGG	POLG	ENSG00000140521	4.72778268585394	[]	[]	9	hSpCas9	negative selection	3450513
89328450	89328473	15	+	26780180	HT29	viability (Avana library 4 designs)	CCTCACCTCTCCAAGAAGAGCGG	POLG	ENSG00000140521	5.86845682827222	[]	[]	9	hSpCas9	negative selection	3450514
89333181	89333204	15	-	26780180	HT29	viability (Avana library 4 designs)	CGTACCCGTGGCCATCCCCGAGG	POLG	ENSG00000140521	3.9241353808523	[]	[]	9	hSpCas9	negative selection	3450515
89333457	89333480	15	-	26780180	HT29	viability (Avana library 4 designs)	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	0.444956800544521	[]	[]	1	hSpCas9	negative selection	3450516
89328450	89328473	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCACCTCTCCAAGAAGAGCGG	POLG	ENSG00000140521	-6.61229089353654	[]	[]	-6	hSpCas9	negative selection	3545795
89333457	89333480	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	5.40551012447358	[]	[]	8	hSpCas9	negative selection	3545796
89333181	89333204	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGTACCCGTGGCCATCCCCGAGG	POLG	ENSG00000140521	-5.5554141936497	[]	[]	-6	hSpCas9	negative selection	3545797
89333509	89333532	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACATCCAGATGCTCTCGAGAGGG	POLG	ENSG00000140521	-19.629169040789	[]	[]	-9	hSpCas9	negative selection	3545798
89326915	89326938	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGATCCATGGGATCACCAGGG	POLG	ENSG00000140521	-1.13879622595438	[]	[]	-1	hSpCas9	negative selection	3545799
89325546	89325569	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGACGCTCTGAGTAGTGCAGAGG	POLG	ENSG00000140521	-6.75415066846472	[]	[]	-6	hSpCas9	negative selection	3545800
89328450	89328473	15	+	26780180	A375	viability (Avana lentiGuide)	CCTCACCTCTCCAAGAAGAGCGG	POLG	ENSG00000140521	21.8256073625726	[]	[]	9	hSpCas9	negative selection	3654454
89333457	89333480	15	-	26780180	A375	viability (Avana lentiGuide)	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	2.69963435368439	[]	[]	3	hSpCas9	negative selection	3654455
89333181	89333204	15	-	26780180	A375	viability (Avana lentiGuide)	CGTACCCGTGGCCATCCCCGAGG	POLG	ENSG00000140521	23.0886031782698	[]	[]	9	hSpCas9	negative selection	3654456
89333509	89333532	15	-	26780180	A375	viability (Avana lentiGuide)	ACATCCAGATGCTCTCGAGAGGG	POLG	ENSG00000140521	22.5155490477596	[]	[]	9	hSpCas9	negative selection	3654457
89326915	89326938	15	+	26780180	A375	viability (Avana lentiGuide)	CCTGATCCATGGGATCACCAGGG	POLG	ENSG00000140521	9.86263873216885	[]	[]	6	hSpCas9	negative selection	3654458
89325546	89325569	15	+	26780180	A375	viability (Avana lentiGuide)	TGACGCTCTGAGTAGTGCAGAGG	POLG	ENSG00000140521	10.9391458313903	[]	[]	7	hSpCas9	negative selection	3654459
89328450	89328473	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCACCTCTCCAAGAAGAGCGG	POLG	ENSG00000140521	0.1386134417575396	[5]	[6,5]	3	hSpCas9	positive selection	3763113
89333457	89333480	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	0.24388595148614445	[4]	[5,5]	7	hSpCas9	positive selection	3763114
89333181	89333204	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTACCCGTGGCCATCCCCGAGG	POLG	ENSG00000140521	0.1230656276034079	[4]	[4,5]	3	hSpCas9	positive selection	3763115
89333509	89333532	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACATCCAGATGCTCTCGAGAGGG	POLG	ENSG00000140521	-0.13787352836182717	[6]	[4,5]	-2	hSpCas9	positive selection	3763116
89326915	89326938	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGATCCATGGGATCACCAGGG	POLG	ENSG00000140521	-0.02389737278508789	[5]	[5,4]	0	hSpCas9	positive selection	3763117
89325546	89325569	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGACGCTCTGAGTAGTGCAGAGG	POLG	ENSG00000140521	-0.05640924163692157	[4]	[4,3]	-1	hSpCas9	positive selection	3763118
89328450	89328473	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCACCTCTCCAAGAAGAGCGG	POLG	ENSG00000140521	0.24975813553004386	[6]	[6,6]	6	hSpCas9	positive selection	3871720
89333457	89333480	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	-0.003357370670621529	[4]	[5,2]	0	hSpCas9	positive selection	3871721
89333181	89333204	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTACCCGTGGCCATCCCCGAGG	POLG	ENSG00000140521	-0.06444741534098479	[5]	[4,4]	-1	hSpCas9	positive selection	3871722
89333509	89333532	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACATCCAGATGCTCTCGAGAGGG	POLG	ENSG00000140521	0.04615318437040647	[6]	[5,5]	1	hSpCas9	positive selection	3871723
89326915	89326938	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGATCCATGGGATCACCAGGG	POLG	ENSG00000140521	-0.20359228567768425	[5]	[3,3]	-3	hSpCas9	positive selection	3871724
89325546	89325569	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGACGCTCTGAGTAGTGCAGAGG	POLG	ENSG00000140521	-1.478723435776291	[4]	[0,1]	-9	hSpCas9	positive selection	3871725
89327213	89327236	15	+	26780180	A375	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	2.75349097158059	[]	[]	9	hSpCas9	negative selection	3982550
89328716	89328739	15	+	26780180	A375	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	1.60197216485501	[]	[]	8	hSpCas9	negative selection	3982551
89328511	89328534	15	-	26780180	A375	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	2.23856245907283	[]	[]	9	hSpCas9	negative selection	3982552
89328511	89328534	15	+	26780180	A375	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	1.70547088471218	[]	[]	9	hSpCas9	negative selection	3982553
89327201	89327224	15	-	26780180	A375	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	2.24974738994346	[]	[]	9	hSpCas9	negative selection	3982554
89328717	89328740	15	-	26780180	A375	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	1.71574089121396	[]	[]	9	hSpCas9	negative selection	3982555
89327213	89327236	15	+	26780180	HT29	viability (GeCKOv2 library)	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	3.16138737462382	[]	[]	9	hSpCas9	negative selection	4090516
89328716	89328739	15	+	26780180	HT29	viability (GeCKOv2 library)	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	1.73576423376416	[]	[]	8	hSpCas9	negative selection	4090517
89328511	89328534	15	-	26780180	HT29	viability (GeCKOv2 library)	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	3.38301187095299	[]	[]	9	hSpCas9	negative selection	4090518
89328511	89328534	15	+	26780180	HT29	viability (GeCKOv2 library)	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.740484837145373	[]	[]	3	hSpCas9	negative selection	4090519
89327201	89327224	15	-	26780180	HT29	viability (GeCKOv2 library)	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	2.04560918805983	[]	[]	9	hSpCas9	negative selection	4090520
89328717	89328740	15	-	26780180	HT29	viability (GeCKOv2 library)	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	0.676889791704854	[]	[]	2	hSpCas9	negative selection	4090521
89328716	89328739	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	0.4856943192142082	[2]	[3,0]	9	hSpCas9	positive selection	4161746
89328511	89328534	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.04635124861923204	[4]	[2,2]	-1	hSpCas9	positive selection	4161747
89328684	89328707	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGACATTCGTGAGAACTTCCAGG	POLG	ENSG00000140521	0.3437875986321053	[2]	[1,1]	8	hSpCas9	positive selection	4161748
89328716	89328739	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	0.39914178713577064	[3]	[0,0,0,2]	3	hSpCas9	positive selection	4225768
89328511	89328534	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.6487462203994918	[4]	[2,2,0,3]	4	hSpCas9	positive selection	4225769
89328684	89328707	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGACATTCGTGAGAACTTCCAGG	POLG	ENSG00000140521	-0.16298392344498308	[2]	[0,2,0,0]	-2	hSpCas9	positive selection	4225770
89327213	89327236	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.48365758204614456	[4]	[2,1]	-8	hSpCas9	positive selection	4291171
89327201	89327224	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	-0.3053945687938238	[3]	[2,1]	-6	hSpCas9	positive selection	4291172
89328717	89328740	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	0.16501155780095295	[3]	[2,2]	3	hSpCas9	positive selection	4291173
89328716	89328739	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.17382222604995218	[2]	[1,1]	-4	hSpCas9	positive selection	4355420
89328511	89328534	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.20954942882036748	[4]	[3,3]	4	hSpCas9	positive selection	4355421
89328511	89328534	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.1856609859860227	[3]	[2,2]	-4	hSpCas9	positive selection	4355422
89325646	89325668	15	+	27760321	OCIAML3	viability	ATGCAGGGTCGTCTAGCCGGGG	POLG	ENSG00000140521	0.3915118601927645	[1038,855]	[924,1022]	5	hSpCas9	negative selection	4429175
89330100	89330122	15	+	27760321	OCIAML3	viability	CTGATATGAGCTCGGTCAAAGG	POLG	ENSG00000140521	-1.256305660588554	[401,347]	[131,109]	-8	hSpCas9	negative selection	4429176
89333209	89333231	15	-	27760321	OCIAML3	viability	GACCCGGTACGGCCCCGAGGGG	POLG	ENSG00000140521	-1.8276722904211866	[751,624]	[124,184]	-9	hSpCas9	negative selection	4429177
89333483	89333505	15	-	27760321	OCIAML3	viability	ACGAGCAAATCTTCGGGCAAGG	POLG	ENSG00000140521	0.3753223749554006	[710,520]	[569,682]	4	hSpCas9	negative selection	4429178
89333558	89333580	15	-	27760321	OCIAML3	viability	CGCAAGTGCTATCCTCGGAGGG	POLG	ENSG00000140521	0.15646591122471376	[522,408]	[389,420]	1	hSpCas9	negative selection	4429179
89325646	89325668	15	+	27760321	OCIAML2	viability	ATGCAGGGTCGTCTAGCCGGGG	POLG	ENSG00000140521	0.5571264182180093	[1038,855]	[961,1333]	7	hSpCas9	negative selection	4512638
89330100	89330122	15	+	27760321	OCIAML2	viability	CTGATATGAGCTCGGTCAAAGG	POLG	ENSG00000140521	-1.0598274582074383	[401,347]	[145,143]	-7	hSpCas9	negative selection	4512639
89333209	89333231	15	-	27760321	OCIAML2	viability	GACCCGGTACGGCCCCGAGGGG	POLG	ENSG00000140521	-1.2279069897198664	[751,624]	[165,329]	-8	hSpCas9	negative selection	4512640
89333483	89333505	15	-	27760321	OCIAML2	viability	ACGAGCAAATCTTCGGGCAAGG	POLG	ENSG00000140521	-0.9623860108860578	[710,520]	[223,291]	-7	hSpCas9	negative selection	4512641
89333558	89333580	15	-	27760321	OCIAML2	viability	CGCAAGTGCTATCCTCGGAGGG	POLG	ENSG00000140521	-0.9529952257493041	[522,408]	[132,272]	-7	hSpCas9	negative selection	4512642
89325646	89325668	15	+	27760321	MV411	viability	ATGCAGGGTCGTCTAGCCGGGG	POLG	ENSG00000140521	0.11860682625366792	[1038,855]	[530,892]	0	hSpCas9	negative selection	4596101
89330100	89330122	15	+	27760321	MV411	viability	CTGATATGAGCTCGGTCAAAGG	POLG	ENSG00000140521	-0.40414633604296485	[401,347]	[80,344]	-3	hSpCas9	negative selection	4596102
89333209	89333231	15	-	27760321	MV411	viability	GACCCGGTACGGCCCCGAGGGG	POLG	ENSG00000140521	-1.4061746310960261	[751,624]	[41,363]	-7	hSpCas9	negative selection	4596103
89333483	89333505	15	-	27760321	MV411	viability	ACGAGCAAATCTTCGGGCAAGG	POLG	ENSG00000140521	-1.1423621596147486	[710,520]	[211,137]	-6	hSpCas9	negative selection	4596104
89333558	89333580	15	-	27760321	MV411	viability	CGCAAGTGCTATCCTCGGAGGG	POLG	ENSG00000140521	-1.7062082839707124	[522,408]	[99,83]	-8	hSpCas9	negative selection	4596105
89325646	89325668	15	+	27760321	HL60	viability	ATGCAGGGTCGTCTAGCCGGGG	POLG	ENSG00000140521	0.27683003575574383	[1038,855]	[878,990]	3	hSpCas9	negative selection	4679564
89330100	89330122	15	+	27760321	HL60	viability	CTGATATGAGCTCGGTCAAAGG	POLG	ENSG00000140521	-1.4236848930410364	[401,347]	[76,152]	-8	hSpCas9	negative selection	4679565
89333209	89333231	15	-	27760321	HL60	viability	GACCCGGTACGGCCCCGAGGGG	POLG	ENSG00000140521	-1.7773601403244532	[751,624]	[191,132]	-9	hSpCas9	negative selection	4679566
89333483	89333505	15	-	27760321	HL60	viability	ACGAGCAAATCTTCGGGCAAGG	POLG	ENSG00000140521	-0.08035761628098798	[710,520]	[453,489]	-1	hSpCas9	negative selection	4679567
89333558	89333580	15	-	27760321	HL60	viability	CGCAAGTGCTATCCTCGGAGGG	POLG	ENSG00000140521	-1.2272999547699865	[522,408]	[127,196]	-8	hSpCas9	negative selection	4679568
89325646	89325668	15	+	27760321	HT1080	viability	ATGCAGGGTCGTCTAGCCGGGG	POLG	ENSG00000140521	0.8000301484825434	[855,667]	[465,596]	4	hSpCas9	negative selection	4763027
89330100	89330122	15	+	27760321	HT1080	viability	CTGATATGAGCTCGGTCAAAGG	POLG	ENSG00000140521	-6.948438340021359	[347,271]	[0,0]	-9	hSpCas9	negative selection	4763028
89333209	89333231	15	-	27760321	HT1080	viability	GACCCGGTACGGCCCCGAGGGG	POLG	ENSG00000140521	-7.18587676843644	[624,487]	[1,0]	-9	hSpCas9	negative selection	4763029
89333483	89333505	15	-	27760321	HT1080	viability	ACGAGCAAATCTTCGGGCAAGG	POLG	ENSG00000140521	-1.7863860680200658	[520,406]	[65,39]	-6	hSpCas9	negative selection	4763030
89333558	89333580	15	-	27760321	HT1080	viability	CGCAAGTGCTATCCTCGGAGGG	POLG	ENSG00000140521	-0.05689709692100509	[408,318]	[94,187]	0	hSpCas9	negative selection	4763031
89325646	89325668	15	+	27760321	HT29	viability after 7 days	ATGCAGGGTCGTCTAGCCGGGG	POLG	ENSG00000140521	0.34783693699556806	[855,667]	[1479,1047,1243]	5	hSpCas9	negative selection	4846490
89330100	89330122	15	+	27760321	HT29	viability after 7 days	CTGATATGAGCTCGGTCAAAGG	POLG	ENSG00000140521	0.00060985750269682	[347,271]	[398,404,391]	0	hSpCas9	negative selection	4846491
89333209	89333231	15	-	27760321	HT29	viability after 7 days	GACCCGGTACGGCCCCGAGGGG	POLG	ENSG00000140521	0.17738313252384108	[624,487]	[884,868,686]	2	hSpCas9	negative selection	4846492
89333483	89333505	15	-	27760321	HT29	viability after 7 days	ACGAGCAAATCTTCGGGCAAGG	POLG	ENSG00000140521	0.42820706948089954	[520,406]	[849,637,921]	6	hSpCas9	negative selection	4846493
89333558	89333580	15	-	27760321	HT29	viability after 7 days	CGCAAGTGCTATCCTCGGAGGG	POLG	ENSG00000140521	0.3088663318778431	[408,318]	[399,775,537]	5	hSpCas9	negative selection	4846494
89325646	89325668	15	+	27760321	HT29	viability after 25 days	ATGCAGGGTCGTCTAGCCGGGG	POLG	ENSG00000140521	0.9283013661394723	[855,667]	[1600,1521,1871]	9	hSpCas9	negative selection	4929953
89330100	89330122	15	+	27760321	HT29	viability after 25 days	CTGATATGAGCTCGGTCAAAGG	POLG	ENSG00000140521	-4.685749594476466	[347,271]	[12,25,0]	-9	hSpCas9	negative selection	4929954
89333209	89333231	15	-	27760321	HT29	viability after 25 days	GACCCGGTACGGCCCCGAGGGG	POLG	ENSG00000140521	-2.096966811641936	[624,487]	[72,198,181]	-8	hSpCas9	negative selection	4929955
89333483	89333505	15	-	27760321	HT29	viability after 25 days	ACGAGCAAATCTTCGGGCAAGG	POLG	ENSG00000140521	-1.955964307704161	[520,406]	[39,186,194]	-8	hSpCas9	negative selection	4929956
89333558	89333580	15	-	27760321	HT29	viability after 25 days	CGCAAGTGCTATCCTCGGAGGG	POLG	ENSG00000140521	-0.5514642577246376	[408,318]	[254,243,361]	-5	hSpCas9	negative selection	4929957
89325646	89325668	15	+	27760321	HT29	viability after 22 days	ATGCAGGGTCGTCTAGCCGGGG	POLG	ENSG00000140521	0.8802250126975981	[855,667]	[1519,1517,1830]	8	hSpCas9	negative selection	5013416
89330100	89330122	15	+	27760321	HT29	viability after 22 days	CTGATATGAGCTCGGTCAAAGG	POLG	ENSG00000140521	-2.556621698778814	[347,271]	[5,37,140]	-8	hSpCas9	negative selection	5013417
89333209	89333231	15	-	27760321	HT29	viability after 22 days	GACCCGGTACGGCCCCGAGGGG	POLG	ENSG00000140521	-1.441310361022869	[624,487]	[290,206,210]	-7	hSpCas9	negative selection	5013418
89333483	89333505	15	-	27760321	HT29	viability after 22 days	ACGAGCAAATCTTCGGGCAAGG	POLG	ENSG00000140521	-1.9089499856053953	[520,406]	[126,154,146]	-8	hSpCas9	negative selection	5013419
89333558	89333580	15	-	27760321	HT29	viability after 22 days	CGCAAGTGCTATCCTCGGAGGG	POLG	ENSG00000140521	-0.5309257673241231	[408,318]	[338,177,355]	-5	hSpCas9	negative selection	5013420
89325646	89325668	15	+	27760321	HT29	viability after 19 days	ATGCAGGGTCGTCTAGCCGGGG	POLG	ENSG00000140521	1.2752262453353223	[855,667]	[1952,1548,2781]	9	hSpCas9	negative selection	5096879
89330100	89330122	15	+	27760321	HT29	viability after 19 days	CTGATATGAGCTCGGTCAAAGG	POLG	ENSG00000140521	-1.6052018455705506	[347,271]	[54,114,170]	-7	hSpCas9	negative selection	5096880
89333209	89333231	15	-	27760321	HT29	viability after 19 days	GACCCGGTACGGCCCCGAGGGG	POLG	ENSG00000140521	-0.8144614231303501	[624,487]	[584,326,202]	-6	hSpCas9	negative selection	5096881
89333483	89333505	15	-	27760321	HT29	viability after 19 days	ACGAGCAAATCTTCGGGCAAGG	POLG	ENSG00000140521	0.06885503382898	[520,406]	[285,390,948]	0	hSpCas9	negative selection	5096882
89333558	89333580	15	-	27760321	HT29	viability after 19 days	CGCAAGTGCTATCCTCGGAGGG	POLG	ENSG00000140521	-0.909550793472933	[408,318]	[362,108,207]	-6	hSpCas9	negative selection	5096883
89325646	89325668	15	+	27760321	HT29	viability after 16 days	ATGCAGGGTCGTCTAGCCGGGG	POLG	ENSG00000140521	0.9592687911343818	[855,667]	[1865,1280,1854]	9	hSpCas9	negative selection	5180342
89330100	89330122	15	+	27760321	HT29	viability after 16 days	CTGATATGAGCTCGGTCAAAGG	POLG	ENSG00000140521	-0.6397528760922968	[347,271]	[242,289,134]	-6	hSpCas9	negative selection	5180343
89333209	89333231	15	-	27760321	HT29	viability after 16 days	GACCCGGTACGGCCCCGAGGGG	POLG	ENSG00000140521	0.7356576339616355	[624,487]	[971,1076,1053]	8	hSpCas9	negative selection	5180344
89333483	89333505	15	-	27760321	HT29	viability after 16 days	ACGAGCAAATCTTCGGGCAAGG	POLG	ENSG00000140521	-0.6536657815175195	[520,406]	[304,314,367]	-6	hSpCas9	negative selection	5180345
89333558	89333580	15	-	27760321	HT29	viability after 16 days	CGCAAGTGCTATCCTCGGAGGG	POLG	ENSG00000140521	0.251402120076333	[408,318]	[587,366,511]	2	hSpCas9	negative selection	5180346
89325646	89325668	15	+	27760321	HT29	viability after 13 days	ATGCAGGGTCGTCTAGCCGGGG	POLG	ENSG00000140521	0.7884034386002841	[855,667]	[1572,1428,1574]	9	hSpCas9	negative selection	5263805
89330100	89330122	15	+	27760321	HT29	viability after 13 days	CTGATATGAGCTCGGTCAAAGG	POLG	ENSG00000140521	-0.18014571062287893	[347,271]	[183,406,358]	-2	hSpCas9	negative selection	5263806
89333209	89333231	15	-	27760321	HT29	viability after 13 days	GACCCGGTACGGCCCCGAGGGG	POLG	ENSG00000140521	0.47037929243309284	[624,487]	[864,968,851]	6	hSpCas9	negative selection	5263807
89333483	89333505	15	-	27760321	HT29	viability after 13 days	ACGAGCAAATCTTCGGGCAAGG	POLG	ENSG00000140521	0.6392570360816268	[520,406]	[916,946,661]	8	hSpCas9	negative selection	5263808
89333558	89333580	15	-	27760321	HT29	viability after 13 days	CGCAAGTGCTATCCTCGGAGGG	POLG	ENSG00000140521	0.2559048736092155	[408,318]	[528,521,463]	3	hSpCas9	negative selection	5263809
89325646	89325668	15	+	27760321	HT29	viability after 10 days	ATGCAGGGTCGTCTAGCCGGGG	POLG	ENSG00000140521	0.6828656427365225	[855,667]	[1597,1001,1956]	8	hSpCas9	negative selection	5347268
89330100	89330122	15	+	27760321	HT29	viability after 10 days	CTGATATGAGCTCGGTCAAAGG	POLG	ENSG00000140521	-0.07100836078189154	[347,271]	[464,436,208]	-1	hSpCas9	negative selection	5347269
89333209	89333231	15	-	27760321	HT29	viability after 10 days	GACCCGGTACGGCCCCGAGGGG	POLG	ENSG00000140521	0.6942727217322665	[624,487]	[1332,675,1345]	8	hSpCas9	negative selection	5347270
89333483	89333505	15	-	27760321	HT29	viability after 10 days	ACGAGCAAATCTTCGGGCAAGG	POLG	ENSG00000140521	0.2929978273102449	[520,406]	[854,336,921]	4	hSpCas9	negative selection	5347271
89333558	89333580	15	-	27760321	HT29	viability after 10 days	CGCAAGTGCTATCCTCGGAGGG	POLG	ENSG00000140521	0.16280628323522514	[408,318]	[317,590,616]	2	hSpCas9	negative selection	5347272
89325646	89325668	15	+	27760321	MOLM13	viability	ATGCAGGGTCGTCTAGCCGGGG	POLG	ENSG00000140521	0.9464012328488285	[1038,855]	[1248,834]	6	hSpCas9	negative selection	5430731
89330100	89330122	15	+	27760321	MOLM13	viability	CTGATATGAGCTCGGTCAAAGG	POLG	ENSG00000140521	-0.3992894596816324	[401,347]	[159,159]	-3	hSpCas9	negative selection	5430732
89333209	89333231	15	-	27760321	MOLM13	viability	GACCCGGTACGGCCCCGAGGGG	POLG	ENSG00000140521	-1.1010340377352623	[751,624]	[276,97]	-6	hSpCas9	negative selection	5430733
89333483	89333505	15	-	27760321	MOLM13	viability	ACGAGCAAATCTTCGGGCAAGG	POLG	ENSG00000140521	-1.5651165540658503	[710,520]	[77,148]	-7	hSpCas9	negative selection	5430734
89333558	89333580	15	-	27760321	MOLM13	viability	CGCAAGTGCTATCCTCGGAGGG	POLG	ENSG00000140521	-1.2663178714860766	[522,408]	[174,51]	-6	hSpCas9	negative selection	5430735
89334334	89334357	15	+	27661255	K562	viability	GGCAAGCGCTCGGCAAATGGTGG	POLG	ENSG00000140521	0.07923526127285108	[445,476]	[422,359]	2	dCas9-KRAB	negative selection	5503019
89334592	89334615	15	+	27661255	K562	viability	GCCTCGCTCCCTGACTGGAGAGG	POLG	ENSG00000140521	-0.3451989809154493	[792,735]	[597,381]	-7	dCas9-KRAB	negative selection	5503020
89334764	89334787	15	+	27661255	K562	viability	GGTAGCGTGTGGCCTCCACCCGG	POLG	ENSG00000140521	-1.3946262535914342	[1328,1153]	[409,350]	-9	dCas9-KRAB	negative selection	5503021
89334437	89334460	15	-	27661255	K562	viability	GGTGTGGGTGTGGGTCCCGGGGG	POLG	ENSG00000140521	0.15456276945460545	[1242,1064]	[1232,854]	5	dCas9-KRAB	negative selection	5503022
89334758	89334781	15	-	27661255	K562	viability	GGAGGCCACACGCTACCCCGAGG	POLG	ENSG00000140521	-0.16154040649446214	[770,860]	[694,484]	-5	dCas9-KRAB	negative selection	5503023
89334826	89334849	15	-	27661255	K562	viability	GGTAGCCGCGGGACCTAGCTGGG	POLG	ENSG00000140521	0.26712069812128547	[544,615]	[633,490]	8	dCas9-KRAB	negative selection	5503024
89327213	89327236	15	+	27260156	BXPC3	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.28967582895138744	[1173]	[813,914,1112,1222]	-6	hSpCas9	negative selection	5563631
89327201	89327224	15	-	27260156	BXPC3	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.14768455179364148	[670]	[612,815,753,957]	3	hSpCas9	negative selection	5563632
89328717	89328740	15	-	27260156	BXPC3	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.33018124038365965	[496]	[390,378,447,440]	-6	hSpCas9	negative selection	5563633
89328716	89328739	15	+	27260156	BXPC3	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.6006751423152935	[328]	[289,240,190,167]	-8	hSpCas9	negative selection	5627880
89328511	89328534	15	+	27260156	BXPC3	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.19576441354932084	[1115]	[874,967,1034,1235]	-4	hSpCas9	negative selection	5627881
89328511	89328534	15	-	27260156	BXPC3	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.5147715940325416	[959]	[704,643,718,745]	-8	hSpCas9	negative selection	5627882
89327213	89327236	15	+	27260156	A673	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	0.025318287112931825	[1173]	[1467,1431,1211,1640]	0	hSpCas9	negative selection	5684882
89327201	89327224	15	-	27260156	A673	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.2391885184459478	[670]	[1015,837,1020,935]	5	hSpCas9	negative selection	5684883
89328717	89328740	15	-	27260156	A673	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.12510194766989435	[496]	[478,534,566,601]	-3	hSpCas9	negative selection	5684884
89328716	89328739	15	+	27260156	A673	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.20160428479786963	[328]	[398,311,322,346]	-5	hSpCas9	negative selection	5749131
89328511	89328534	15	+	27260156	A673	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.1106718575229726	[1115]	[1435,973,1329,1250]	-3	hSpCas9	negative selection	5749132
89328511	89328534	15	-	27260156	A673	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.23847857810360673	[959]	[967,907,1102,923]	-5	hSpCas9	negative selection	5749133
89327213	89327236	15	+	27260156	A375	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.2528118207019707	[1173]	[1060,1262,1224,1073]	-4	hSpCas9	negative selection	5806133
89327201	89327224	15	-	27260156	A375	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	-0.08970518541599859	[670]	[701,812,845,607]	-1	hSpCas9	negative selection	5806134
89328717	89328740	15	-	27260156	A375	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.8405192779138626	[496]	[396,259,397,241]	-8	hSpCas9	negative selection	5806135
89328716	89328739	15	+	27260156	A375	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-1.3229536652183476	[328]	[54,314,60,198]	-9	hSpCas9	negative selection	5870382
89328511	89328534	15	+	27260156	A375	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.3800252048012994	[1115]	[1282,1228,852,706]	-5	hSpCas9	negative selection	5870383
89328511	89328534	15	-	27260156	A375	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.7017211145177857	[959]	[539,720,731,756]	-7	hSpCas9	negative selection	5870384
89327213	89327236	15	+	27260156	COLO741	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.16637812512826633	[1173]	[1370,1402,1242]	-4	hSpCas9	negative selection	5927384
89327201	89327224	15	-	27260156	COLO741	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.1602735402023947	[670]	[994,1156,739]	3	hSpCas9	negative selection	5927385
89328717	89328740	15	-	27260156	COLO741	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	0.0309354117395082	[496]	[676,673,599]	0	hSpCas9	negative selection	5927386
89328716	89328739	15	+	27260156	COLO741	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.2926789008703681	[328]	[245,490,287]	-6	hSpCas9	negative selection	5991633
89328511	89328534	15	+	27260156	COLO741	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.13507603268423019	[1115]	[1383,1417,1111]	-3	hSpCas9	negative selection	5991634
89328511	89328534	15	-	27260156	COLO741	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.28617024100311117	[959]	[1127,883,1012]	-6	hSpCas9	negative selection	5991635
89327213	89327236	15	+	27260156	CAL120	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.1700862140275834	[1173]	[1446,1163,1305]	-3	hSpCas9	negative selection	6048635
89327201	89327224	15	-	27260156	CAL120	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.3379658328495442	[670]	[1440,907,877]	5	hSpCas9	negative selection	6048636
89328717	89328740	15	-	27260156	CAL120	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.04209724451656807	[496]	[542,643,605]	0	hSpCas9	negative selection	6048637
89328716	89328739	15	+	27260156	CAL120	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.5335521589609539	[328]	[264,369,211]	-6	hSpCas9	negative selection	6112884
89328511	89328534	15	+	27260156	CAL120	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.3645581556938935	[1115]	[1838,1750,1780]	5	hSpCas9	negative selection	6112885
89328511	89328534	15	-	27260156	CAL120	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.6400794511806771	[959]	[1077,545,722]	-7	hSpCas9	negative selection	6112886
89327213	89327236	15	+	27260156	CADOES1	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.07874797800624411	[1173]	[1115,1082,888,1047]	-1	hSpCas9	negative selection	6169886
89327201	89327224	15	-	27260156	CADOES1	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.4478055796207261	[670]	[886,808,873,833]	7	hSpCas9	negative selection	6169887
89328717	89328740	15	-	27260156	CADOES1	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.028219207571358457	[496]	[561,423,368,457]	0	hSpCas9	negative selection	6169888
89328716	89328739	15	+	27260156	CADOES1	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.1778500437249565	[328]	[252,168,307,354]	-3	hSpCas9	negative selection	6234135
89328511	89328534	15	+	27260156	CADOES1	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.05868316079075142	[1115]	[895,985,1089,1362]	1	hSpCas9	negative selection	6234136
89328511	89328534	15	-	27260156	CADOES1	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.21946078554149717	[959]	[620,758,863,825]	-4	hSpCas9	negative selection	6234137
89327213	89327236	15	+	27260156	EWS502	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.3060902249385318	[1173]	[980,834,1144,1074]	-5	hSpCas9	negative selection	6291137
89327201	89327224	15	-	27260156	EWS502	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	-0.05506531089742145	[670]	[624,529,803,797]	-1	hSpCas9	negative selection	6291138
89328717	89328740	15	-	27260156	EWS502	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.29269899636182894	[496]	[327,407,541,455]	-5	hSpCas9	negative selection	6291139
89328716	89328739	15	+	27260156	EWS502	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-1.1889263937954606	[328]	[131,199,174,100]	-9	hSpCas9	negative selection	6355386
89328511	89328534	15	+	27260156	EWS502	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.2094645060025595	[1115]	[1094,1013,986,976]	-4	hSpCas9	negative selection	6355387
89328511	89328534	15	-	27260156	EWS502	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.7373451047310096	[959]	[393,555,779,747]	-8	hSpCas9	negative selection	6355388
89327213	89327236	15	+	27260156	EW8	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.2967641787764199	[1173]	[866,894,643,722]	-5	hSpCas9	negative selection	6412388
89327201	89327224	15	-	27260156	EW8	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.24206158025589808	[670]	[837,708,409,674]	4	hSpCas9	negative selection	6412389
89328717	89328740	15	-	27260156	EW8	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.28871860579589503	[496]	[261,470,223,371]	-5	hSpCas9	negative selection	6412390
89328716	89328739	15	+	27260156	EW8	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.8398603820818195	[328]	[220,142,85,163]	-9	hSpCas9	negative selection	6476637
89328511	89328534	15	+	27260156	EW8	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.31854343091062776	[1115]	[764,656,855,602]	-5	hSpCas9	negative selection	6476638
89328511	89328534	15	-	27260156	EW8	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.5585993884789756	[959]	[535,597,394,605]	-7	hSpCas9	negative selection	6476639
89327213	89327236	15	+	27260156	CORL105	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.024597216570739544	[1173]	[1175,1354,1617,1290]	0	hSpCas9	negative selection	6533639
89327201	89327224	15	-	27260156	CORL105	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.18835372835682207	[670]	[845,758,899,1075]	3	hSpCas9	negative selection	6533640
89328717	89328740	15	-	27260156	CORL105	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.3015466168565733	[496]	[491,430,605,381]	-5	hSpCas9	negative selection	6533641
89328716	89328739	15	+	27260156	CORL105	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.6546895052982732	[328]	[244,210,212,304]	-8	hSpCas9	negative selection	6597888
89328511	89328534	15	+	27260156	CORL105	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.03757308583101282	[1115]	[1217,1364,1162,1323]	0	hSpCas9	negative selection	6597889
89328511	89328534	15	-	27260156	CORL105	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.43810000883268463	[959]	[670,920,1058,695]	-7	hSpCas9	negative selection	6597890
89327213	89327236	15	+	27260156	HS294T	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.22737970329329782	[1173]	[367,250,375,595]	-3	hSpCas9	negative selection	6654890
89327201	89327224	15	-	27260156	HS294T	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	-0.304843488751946	[670]	[193,174,228,250]	-4	hSpCas9	negative selection	6654891
89328717	89328740	15	-	27260156	HS294T	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.4485046231459506	[496]	[107,194,125,133]	-6	hSpCas9	negative selection	6654892
89328716	89328739	15	+	27260156	HS294T	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-1.356091681264966	[328]	[20,28,67,90]	-9	hSpCas9	negative selection	6719139
89328511	89328534	15	+	27260156	HS294T	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.329202468575611	[1115]	[477,454,549,722]	4	hSpCas9	negative selection	6719140
89328511	89328534	15	-	27260156	HS294T	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.08790773771708627	[959]	[270,258,309,609]	-1	hSpCas9	negative selection	6719141
89327213	89327236	15	+	27260156	HCC44	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.3460927723175454	[1173]	[866,1126,1170,999]	-5	hSpCas9	negative selection	6776141
89327201	89327224	15	-	27260156	HCC44	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.24801140610563677	[670]	[1111,1012,823,646]	4	hSpCas9	negative selection	6776142
89328717	89328740	15	-	27260156	HCC44	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.6852423719538591	[496]	[418,209,541,285]	-7	hSpCas9	negative selection	6776143
89328716	89328739	15	+	27260156	HCC44	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-1.0390859467375404	[328]	[158,231,156,161]	-8	hSpCas9	negative selection	6840390
89328511	89328534	15	+	27260156	HCC44	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.06874943075610829	[1115]	[1269,872,1598,1183]	-1	hSpCas9	negative selection	6840391
89328511	89328534	15	-	27260156	HCC44	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.7542684661873416	[959]	[880,543,744,458]	-8	hSpCas9	negative selection	6840392
89327213	89327236	15	+	27260156	G402	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.007685980951448457	[1173]	[1708,1350,1143,1521]	0	hSpCas9	negative selection	6897392
89327201	89327224	15	-	27260156	G402	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.38337713154807807	[670]	[1486,1256,860,749]	5	hSpCas9	negative selection	6897393
89328717	89328740	15	-	27260156	G402	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.06942455896931575	[496]	[351,1179,542,252]	-1	hSpCas9	negative selection	6897394
89328716	89328739	15	+	27260156	G402	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-1.0452602794387236	[328]	[226,266,134,158]	-8	hSpCas9	negative selection	6961641
89328511	89328534	15	+	27260156	G402	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.27357346211412437	[1115]	[945,1260,1372,913]	-3	hSpCas9	negative selection	6961642
89328511	89328534	15	-	27260156	G402	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.7046747874378332	[959]	[1112,766,461,595]	-7	hSpCas9	negative selection	6961643
89327213	89327236	15	+	27260156	L33	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	0.11034699788708169	[1173]	[1228,465,791,1441]	2	hSpCas9	negative selection	7018643
89327201	89327224	15	-	27260156	L33	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.05485570259089523	[670]	[725,268,477,644]	1	hSpCas9	negative selection	7018644
89328717	89328740	15	-	27260156	L33	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	0.2911022033244576	[496]	[557,211,485,585]	6	hSpCas9	negative selection	7018645
89328716	89328739	15	+	27260156	L33	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.221589094593989	[328]	[258,121,121,376]	-5	hSpCas9	negative selection	7082892
89328511	89328534	15	+	27260156	L33	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.09252308088923966	[1115]	[1021,481,864,1189]	2	hSpCas9	negative selection	7082893
89328511	89328534	15	-	27260156	L33	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.22389154073870055	[959]	[769,287,562,919]	-5	hSpCas9	negative selection	7082894
89327213	89327236	15	+	27260156	K562	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.38607457312542737	[1173]	[897,786,859,663]	-5	hSpCas9	negative selection	7139894
89327201	89327224	15	-	27260156	K562	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.15226095645592774	[670]	[726,427,742,730]	1	hSpCas9	negative selection	7139895
89328717	89328740	15	-	27260156	K562	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.242667887260877	[496]	[525,343,450,199]	-3	hSpCas9	negative selection	7139896
89328716	89328739	15	+	27260156	K562	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.77089320534312	[328]	[406,62,71,156]	-7	hSpCas9	negative selection	7204143
89328511	89328534	15	+	27260156	K562	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.15963432160077318	[1115]	[1476,1379,982,675]	2	hSpCas9	negative selection	7204144
89328511	89328534	15	-	27260156	K562	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.8902743183019224	[959]	[470,466,384,508]	-7	hSpCas9	negative selection	7204145
89327213	89327236	15	+	27260156	HT29	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.5295554204756333	[1173]	[1002,1156,939,876]	-7	hSpCas9	negative selection	7261145
89327201	89327224	15	-	27260156	HT29	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.10878443933470361	[670]	[1037,1099,642,774]	2	hSpCas9	negative selection	7261146
89328717	89328740	15	-	27260156	HT29	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	0.07556073902480305	[496]	[496,728,782,541]	1	hSpCas9	negative selection	7261147
89328716	89328739	15	+	27260156	HT29	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.7047504657179448	[328]	[201,351,270,169]	-8	hSpCas9	negative selection	7325394
89328511	89328534	15	+	27260156	HT29	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.10872548345830957	[1115]	[1301,1454,1282,1031]	-2	hSpCas9	negative selection	7325395
89328511	89328534	15	-	27260156	HT29	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.5422177489760973	[959]	[901,973,784,587]	-7	hSpCas9	negative selection	7325396
89327213	89327236	15	+	27260156	MHHES1	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	0.02375250778063731	[1173]	[1590,1534,1165,1147]	0	hSpCas9	negative selection	7382396
89327201	89327224	15	-	27260156	MHHES1	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.1359047687820233	[670]	[1300,978,551,595]	2	hSpCas9	negative selection	7382397
89328717	89328740	15	-	27260156	MHHES1	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.2472515073941266	[496]	[419,579,429,453]	-5	hSpCas9	negative selection	7382398
89328716	89328739	15	+	27260156	MHHES1	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.6320548871879949	[328]	[332,125,349,160]	-8	hSpCas9	negative selection	7446645
89328511	89328534	15	+	27260156	MHHES1	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.34035006382943167	[1115]	[925,924,1172,925]	-6	hSpCas9	negative selection	7446646
89328511	89328534	15	-	27260156	MHHES1	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.42787015592732547	[959]	[804,1069,792,602]	-7	hSpCas9	negative selection	7446647
89327213	89327236	15	+	27260156	MEWO	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	0.20659289240887668	[1173]	[1471,1410,957]	4	hSpCas9	negative selection	7503647
89327201	89327224	15	-	27260156	MEWO	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.17092644065008822	[670]	[903,753,499]	4	hSpCas9	negative selection	7503648
89328717	89328740	15	-	27260156	MEWO	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.149730146744113	[496]	[473,407,385]	-3	hSpCas9	negative selection	7503649
89328716	89328739	15	+	27260156	MEWO	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.35948561528941925	[328]	[283,285,157]	-7	hSpCas9	negative selection	7567896
89328511	89328534	15	+	27260156	MEWO	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.0063292917002986115	[1115]	[1303,948,916]	0	hSpCas9	negative selection	7567897
89328511	89328534	15	-	27260156	MEWO	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	0.07659425339600268	[959]	[998,982,868]	1	hSpCas9	negative selection	7567898
89327213	89327236	15	+	27260156	LNCAPCLONEFGC	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.4192554423680017	[1173]	[730,690,931,854]	-6	hSpCas9	negative selection	7624898
89327201	89327224	15	-	27260156	LNCAPCLONEFGC	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.1648760142923522	[670]	[628,577,808,735]	2	hSpCas9	negative selection	7624899
89328717	89328740	15	-	27260156	LNCAPCLONEFGC	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.7094101823712237	[496]	[259,303,338,205]	-8	hSpCas9	negative selection	7624900
89328716	89328739	15	+	27260156	LNCAPCLONEFGC	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.35546518721185916	[328]	[148,392,241,139]	-5	hSpCas9	negative selection	7689147
89328511	89328534	15	+	27260156	LNCAPCLONEFGC	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.04200403056398705	[1115]	[940,875,1009,1111]	0	hSpCas9	negative selection	7689148
89328511	89328534	15	-	27260156	LNCAPCLONEFGC	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.5180851629634922	[959]	[632,544,780,498]	-7	hSpCas9	negative selection	7689149
89327213	89327236	15	+	27260156	PANC0327	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.14918124163485103	[1173]	[612,1484,740,824]	-2	hSpCas9	negative selection	7746149
89327201	89327224	15	-	27260156	PANC0327	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.13198474834982243	[670]	[953,589,488,611]	2	hSpCas9	negative selection	7746150
89328717	89328740	15	-	27260156	PANC0327	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.7426572346650396	[496]	[506,110,252,223]	-7	hSpCas9	negative selection	7746151
89328716	89328739	15	+	27260156	PANC0327	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-1.3104533015845141	[328]	[114,95,171,90]	-9	hSpCas9	negative selection	7810398
89328511	89328534	15	+	27260156	PANC0327	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.0707545796500002	[1115]	[826,794,1328,1227]	1	hSpCas9	negative selection	7810399
89328511	89328534	15	-	27260156	PANC0327	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.751612898438062	[959]	[660,503,540,332]	-8	hSpCas9	negative selection	7810400
89327213	89327236	15	+	27260156	NCIH2009	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.46350032004854247	[1173]	[1386,1171,1046]	-6	hSpCas9	negative selection	7867400
89327201	89327224	15	-	27260156	NCIH2009	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	-0.09461267845387061	[670]	[1026,707,929]	-1	hSpCas9	negative selection	7867401
89328717	89328740	15	-	27260156	NCIH2009	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.21954454717342659	[496]	[755,410,655]	-3	hSpCas9	negative selection	7867402
89328716	89328739	15	+	27260156	NCIH2009	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-1.4702356615388168	[328]	[200,130,172]	-9	hSpCas9	negative selection	7931649
89328511	89328534	15	+	27260156	NCIH2009	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.2538737315774472	[1115]	[1071,1147,1656]	-3	hSpCas9	negative selection	7931650
89328511	89328534	15	-	27260156	NCIH2009	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.33332089776714446	[959]	[1180,1115,916]	-4	hSpCas9	negative selection	7931651
89327213	89327236	15	+	27260156	NCIH1373	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	0.14582962602250893	[1173]	[1513,1599,1332,356]	1	hSpCas9	negative selection	7988651
89327201	89327224	15	-	27260156	NCIH1373	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.33225215824127763	[670]	[1126,624,1365,184]	3	hSpCas9	negative selection	7988652
89328717	89328740	15	-	27260156	NCIH1373	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.0728716079872487	[496]	[700,360,484,162]	0	hSpCas9	negative selection	7988653
89328716	89328739	15	+	27260156	NCIH1373	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.30696136716307165	[328]	[450,441,161,35]	-3	hSpCas9	negative selection	8052900
89328511	89328534	15	+	27260156	NCIH1373	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.026579440708128566	[1115]	[1060,1738,890,297]	0	hSpCas9	negative selection	8052901
89328511	89328534	15	-	27260156	NCIH1373	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.4906376288049681	[959]	[787,499,1011,206]	-5	hSpCas9	negative selection	8052902
89327213	89327236	15	+	27260156	PATU8902	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.19915859543303216	[1173]	[968,1091,1793,1781]	-2	hSpCas9	negative selection	8109902
89327201	89327224	15	-	27260156	PATU8902	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.13575991070522286	[670]	[781,1328,1117,825]	1	hSpCas9	negative selection	8109903
89328717	89328740	15	-	27260156	PATU8902	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.047016831644432794	[496]	[505,567,567,1113]	0	hSpCas9	negative selection	8109904
89328716	89328739	15	+	27260156	PATU8902	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-1.1177734724641075	[328]	[249,185,157,268]	-7	hSpCas9	negative selection	8174151
89328511	89328534	15	+	27260156	PATU8902	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.26235701296759995	[1115]	[1510,1593,897,1267]	-3	hSpCas9	negative selection	8174152
89328511	89328534	15	-	27260156	PATU8902	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.19568575508051644	[959]	[899,1124,765,2086]	-2	hSpCas9	negative selection	8174153
89327213	89327236	15	+	27260156	PANC1	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.42920831602332077	[1173]	[708,672,818,764]	-6	hSpCas9	negative selection	8231153
89327201	89327224	15	-	27260156	PANC1	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.28363145820859337	[670]	[696,1066,645,493]	4	hSpCas9	negative selection	8231154
89328717	89328740	15	-	27260156	PANC1	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.02981001674985407	[496]	[402,433,386,440]	0	hSpCas9	negative selection	8231155
89328716	89328739	15	+	27260156	PANC1	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.8481361434116538	[328]	[128,163,213,125]	-8	hSpCas9	negative selection	8295402
89328511	89328534	15	+	27260156	PANC1	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.17791209301816702	[1115]	[857,936,621,955]	-3	hSpCas9	negative selection	8295403
89328511	89328534	15	-	27260156	PANC1	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.5762691346496809	[959]	[568,602,525,519]	-7	hSpCas9	negative selection	8295404
89327213	89327236	15	+	27260156	PANC0813	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.012245935557608556	[1173]	[1480,1132,1522,1342]	0	hSpCas9	negative selection	8352404
89327201	89327224	15	-	27260156	PANC0813	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.29012154952041613	[670]	[981,1177,904,798]	5	hSpCas9	negative selection	8352405
89328717	89328740	15	-	27260156	PANC0813	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	0.2220323627431008	[496]	[598,863,838,427]	3	hSpCas9	negative selection	8352406
89328716	89328739	15	+	27260156	PANC0813	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.5278060572486255	[328]	[221,319,215,306]	-7	hSpCas9	negative selection	8416653
89328511	89328534	15	+	27260156	PANC0813	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.10907858763173284	[1115]	[1216,1282,1392,980]	-2	hSpCas9	negative selection	8416654
89328511	89328534	15	-	27260156	PANC0813	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.4506835669338979	[959]	[915,640,890,857]	-6	hSpCas9	negative selection	8416655
89327213	89327236	15	+	27260156	RDES	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	0.19168353972537644	[1173]	[1146,1525,1708,1886]	3	hSpCas9	negative selection	8473655
89327201	89327224	15	-	27260156	RDES	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.3464750321499728	[670]	[774,969,1132,1083]	5	hSpCas9	negative selection	8473656
89328717	89328740	15	-	27260156	RDES	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.021256124826337416	[496]	[535,534,501,685]	0	hSpCas9	negative selection	8473657
89328716	89328739	15	+	27260156	RDES	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.6388897586882408	[328]	[220,177,255,334]	-8	hSpCas9	negative selection	8537904
89328511	89328534	15	+	27260156	RDES	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.16862335062814093	[1115]	[1129,1261,1654,1833]	2	hSpCas9	negative selection	8537905
89328511	89328534	15	-	27260156	RDES	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.11238478541492425	[959]	[895,933,1118,1164]	-2	hSpCas9	negative selection	8537906
89327213	89327236	15	+	27260156	PC3	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.006426300330566459	[1173]	[790,1201,1786,1160]	0	hSpCas9	negative selection	8594906
89327201	89327224	15	-	27260156	PC3	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.2129639200708917	[670]	[623,548,1191,888]	5	hSpCas9	negative selection	8594907
89328717	89328740	15	-	27260156	PC3	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	0.18936206938481692	[496]	[342,611,789,645]	4	hSpCas9	negative selection	8594908
89328716	89328739	15	+	27260156	PC3	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.08697498284447402	[328]	[223,389,382,261]	-2	hSpCas9	negative selection	8659155
89328511	89328534	15	+	27260156	PC3	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.07442781290335443	[1115]	[636,1241,1873,1341]	1	hSpCas9	negative selection	8659156
89328511	89328534	15	-	27260156	PC3	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.34145890716849037	[959]	[404,805,1113,928]	-7	hSpCas9	negative selection	8659157
89327213	89327236	15	+	27260156	PATU8988T	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.367114010422148	[1173]	[1000,790,822,896]	-6	hSpCas9	negative selection	8716157
89327201	89327224	15	-	27260156	PATU8988T	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.06192844934719566	[670]	[703,623,510,881]	1	hSpCas9	negative selection	8716158
89328717	89328740	15	-	27260156	PATU8988T	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.7677338068623392	[496]	[211,344,176,411]	-8	hSpCas9	negative selection	8716159
89328716	89328739	15	+	27260156	PATU8988T	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.8399072890158897	[328]	[287,128,109,179]	-8	hSpCas9	negative selection	8780406
89328511	89328534	15	+	27260156	PATU8988T	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.8191497129191971	[1115]	[380,713,603,767]	-8	hSpCas9	negative selection	8780407
89328511	89328534	15	-	27260156	PATU8988T	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.6828837524675752	[959]	[470,644,602,599]	-8	hSpCas9	negative selection	8780408
89327213	89327236	15	+	27260156	T47D	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.18323269342929427	[1173]	[1138,1357,1200,1102]	-4	hSpCas9	negative selection	8837408
89327201	89327224	15	-	27260156	T47D	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.23581479585375675	[670]	[981,915,991,786]	5	hSpCas9	negative selection	8837409
89328717	89328740	15	-	27260156	T47D	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.11222043761845421	[496]	[506,540,568,523]	-2	hSpCas9	negative selection	8837410
89328716	89328739	15	+	27260156	T47D	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.24212840362141042	[328]	[363,266,303,367]	-5	hSpCas9	negative selection	8901657
89328511	89328534	15	+	27260156	T47D	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.03254576673963738	[1115]	[1377,1142,1204,1373]	0	hSpCas9	negative selection	8901658
89328511	89328534	15	-	27260156	T47D	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.5349201975633218	[959]	[783,616,894,803]	-8	hSpCas9	negative selection	8901659
89327213	89327236	15	+	27260156	SU8686	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	0.07430801754087946	[1173]	[1202,1170,1245,1293]	1	hSpCas9	negative selection	8958659
89327201	89327224	15	-	27260156	SU8686	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.24247989790535796	[670]	[804,619,708,1071]	4	hSpCas9	negative selection	8958660
89328717	89328740	15	-	27260156	SU8686	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	0.0007503797999756645	[496]	[456,459,461,616]	0	hSpCas9	negative selection	8958661
89328716	89328739	15	+	27260156	SU8686	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.4754498492540462	[328]	[245,266,185,229]	-6	hSpCas9	negative selection	9022908
89328511	89328534	15	+	27260156	SU8686	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.0639174161226519	[1115]	[1055,1188,1042,1367]	1	hSpCas9	negative selection	9022909
89328511	89328534	15	-	27260156	SU8686	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.36321695719625424	[959]	[743,738,559,937]	-6	hSpCas9	negative selection	9022910
89327213	89327236	15	+	27260156	SKES1	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	0.015170219940435103	[1173]	[1471,1435,933,977]	0	hSpCas9	negative selection	9079910
89327201	89327224	15	-	27260156	SKES1	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.21704242959093112	[670]	[938,742,731,715]	4	hSpCas9	negative selection	9079911
89328717	89328740	15	-	27260156	SKES1	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.24220529897361748	[496]	[580,381,427,311]	-5	hSpCas9	negative selection	9079912
89328716	89328739	15	+	27260156	SKES1	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.1558776960586945	[328]	[449,215,256,267]	-3	hSpCas9	negative selection	9144159
89328511	89328534	15	+	27260156	SKES1	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.047043979701472116	[1115]	[1086,1383,1062,1082]	1	hSpCas9	negative selection	9144160
89328511	89328534	15	-	27260156	SKES1	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.2139510254652266	[959]	[806,885,727,872]	-5	hSpCas9	negative selection	9144161
89327213	89327236	15	+	27260156	TOV112D	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.2618395903649824	[1173]	[809,1129,1261,747]	-5	hSpCas9	negative selection	9201161
89327201	89327224	15	-	27260156	TOV112D	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.39871550757503527	[670]	[955,1081,905,658]	7	hSpCas9	negative selection	9201162
89328717	89328740	15	-	27260156	TOV112D	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.050583072666198575	[496]	[397,620,475,454]	-1	hSpCas9	negative selection	9201163
89328716	89328739	15	+	27260156	TOV112D	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.7690981441090413	[328]	[218,134,253,153]	-9	hSpCas9	negative selection	9265410
89328511	89328534	15	+	27260156	TOV112D	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	0.06825406388395838	[1115]	[1232,1127,1330,992]	1	hSpCas9	negative selection	9265411
89328511	89328534	15	-	27260156	TOV112D	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.24655328267526322	[959]	[936,618,946,703]	-5	hSpCas9	negative selection	9265412
89327213	89327236	15	+	27260156	TC71	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.12420984325780338	[1173]	[1089,1237,1052,1247]	-3	hSpCas9	negative selection	9322412
89327201	89327224	15	-	27260156	TC71	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.2210867640457317	[670]	[941,772,753,887]	5	hSpCas9	negative selection	9322413
89328717	89328740	15	-	27260156	TC71	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.0213965594739597	[496]	[489,648,470,489]	0	hSpCas9	negative selection	9322414
89328716	89328739	15	+	27260156	TC71	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.1664749757161832	[328]	[346,315,282,310]	-4	hSpCas9	negative selection	9386661
89328511	89328534	15	+	27260156	TC71	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.20355813825234814	[1115]	[1017,1227,857,1058]	-5	hSpCas9	negative selection	9386662
89328511	89328534	15	-	27260156	TC71	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.4201559031643384	[959]	[848,841,691,688]	-8	hSpCas9	negative selection	9386663
89327213	89327236	15	+	27260156	TC32	viability	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	0.029254526476949483	[1173]	[991,778,1537,1362]	0	hSpCas9	negative selection	9443663
89327201	89327224	15	-	27260156	TC32	viability	GAAGAAGTCGTTGATGGATCTGG	POLG	ENSG00000140521	0.4662849442684328	[670]	[832,883,932,781]	7	hSpCas9	negative selection	9443664
89328717	89328740	15	-	27260156	TC32	viability	GCCTCGAGAACTGTTTGTGAAGG	POLG	ENSG00000140521	-0.176152116513025	[496]	[419,275,495,507]	-3	hSpCas9	negative selection	9443665
89328716	89328739	15	+	27260156	TC32	viability	CCCTTCACAAACAGTTCTCGAGG	POLG	ENSG00000140521	-0.369099285366408	[328]	[420,72,249,240]	-6	hSpCas9	negative selection	9507912
89328511	89328534	15	+	27260156	TC32	viability	CCTGGGCACAGTACTGCATCAGG	POLG	ENSG00000140521	-0.15474464131095167	[1115]	[822,688,1144,1217]	-3	hSpCas9	negative selection	9507913
89328511	89328534	15	-	27260156	TC32	viability	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-0.3393116455760905	[959]	[596,404,1175,855]	-6	hSpCas9	negative selection	9507914
89327213	89327236	15	+	27869803	HPAFII	viability after 27 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-2.9129413316171	[111]	[15,0,NaN]	-9	hSpCas9	negative selection	9555261
89328511	89328534	15	-	27869803	HPAFII	viability after 27 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-5.096203385307463	[277]	[0,6,NaN]	-9	hSpCas9	negative selection	9555262
89328757	89328780	15	-	27869803	HPAFII	viability after 27 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-5.3267868270651295	[346]	[3,4,NaN]	-9	hSpCas9	negative selection	9555263
89328942	89328965	15	-	27869803	HPAFII	viability after 27 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-5.905309559789038	[113]	[0,0,NaN]	-9	hSpCas9	negative selection	9555264
89330239	89330262	15	+	27869803	HPAFII	viability after 27 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-4.055413120318606	[45]	[1,0,NaN]	-9	hSpCas9	negative selection	9555265
89333479	89333502	15	-	27869803	HPAFII	viability after 27 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-0.20632083269403592	[239]	[218,17,NaN]	-1	hSpCas9	negative selection	9555266
89327213	89327236	15	+	27869803	HPAFII	viability after 15 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-0.5264348855295347	[111]	[106,68,NaN]	-5	hSpCas9	negative selection	9637710
89328511	89328534	15	-	27869803	HPAFII	viability after 15 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-2.11224990930142	[277]	[94,52,NaN]	-9	hSpCas9	negative selection	9637711
89328757	89328780	15	-	27869803	HPAFII	viability after 15 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-0.7866165214203982	[346]	[275,178,NaN]	-7	hSpCas9	negative selection	9637712
89328942	89328965	15	-	27869803	HPAFII	viability after 15 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-2.1432293965991027	[113]	[44,16,NaN]	-9	hSpCas9	negative selection	9637713
89330239	89330262	15	+	27869803	HPAFII	viability after 15 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-1.7630656931038078	[45]	[0,22,NaN]	-9	hSpCas9	negative selection	9637714
89333479	89333502	15	-	27869803	HPAFII	viability after 15 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-0.6828322829517888	[239]	[283,83,NaN]	-6	hSpCas9	negative selection	9637715
89327213	89327236	15	+	27869803	ASPC1	viability after 36 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-1.441263713481003	[531]	[56,106,44]	-8	hSpCas9	negative selection	9720159
89328511	89328534	15	-	27869803	ASPC1	viability after 36 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-1.0577323089778463	[500]	[63,184,16]	-7	hSpCas9	negative selection	9720160
89328757	89328780	15	-	27869803	ASPC1	viability after 36 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	0.14583810334895608	[1179]	[779,420,250]	1	hSpCas9	negative selection	9720161
89328942	89328965	15	-	27869803	ASPC1	viability after 36 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	0.47556138109429513	[176]	[76,152,37]	5	hSpCas9	negative selection	9720162
89330239	89330262	15	+	27869803	ASPC1	viability after 36 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-0.4617307881938435	[235]	[161,33,7]	-5	hSpCas9	negative selection	9720163
89333479	89333502	15	-	27869803	ASPC1	viability after 36 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-0.48858162891831364	[685]	[244,158,125]	-5	hSpCas9	negative selection	9720164
89327213	89327236	15	+	27869803	PATU8988S	viability after 35 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-5.205506803238325	[503]	[5,4,NaN]	-9	hSpCas9	negative selection	9802608
89328511	89328534	15	-	27869803	PATU8988S	viability after 35 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-2.1998523361531914	[433]	[57,17,NaN]	-9	hSpCas9	negative selection	9802609
89328757	89328780	15	-	27869803	PATU8988S	viability after 35 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-2.5102060349358277	[1082]	[103,48,NaN]	-9	hSpCas9	negative selection	9802610
89328942	89328965	15	-	27869803	PATU8988S	viability after 35 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-0.24764303441600188	[161]	[34,74,NaN]	-3	hSpCas9	negative selection	9802611
89330239	89330262	15	+	27869803	PATU8988S	viability after 35 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-3.260676840988389	[142]	[9,1,NaN]	-9	hSpCas9	negative selection	9802612
89333479	89333502	15	-	27869803	PATU8988S	viability after 35 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-1.251469540478545	[513]	[64,108,NaN]	-8	hSpCas9	negative selection	9802613
89327213	89327236	15	+	27869803	PATU8988S	viability after 31 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-3.8230397844687634	[503]	[11,16,NaN]	-9	hSpCas9	negative selection	9885057
89328511	89328534	15	-	27869803	PATU8988S	viability after 31 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-3.281058176782805	[433]	[30,0,NaN]	-9	hSpCas9	negative selection	9885058
89328757	89328780	15	-	27869803	PATU8988S	viability after 31 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-2.767856843840662	[1082]	[80,40,NaN]	-9	hSpCas9	negative selection	9885059
89328942	89328965	15	-	27869803	PATU8988S	viability after 31 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-0.8741331106068069	[161]	[47,18,NaN]	-7	hSpCas9	negative selection	9885060
89330239	89330262	15	+	27869803	PATU8988S	viability after 31 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-0.5870270834481999	[142]	[33,42,NaN]	-6	hSpCas9	negative selection	9885061
89333479	89333502	15	-	27869803	PATU8988S	viability after 31 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	-1.345662225804114	[513]	[99,55,NaN]	-8	hSpCas9	negative selection	9885062
89327213	89327236	15	+	27869803	HPAFII	viability after 35 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-2.178447999373005	[111]	[4,20,NaN]	-8	hSpCas9	negative selection	9967506
89328511	89328534	15	-	27869803	HPAFII	viability after 35 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-7.136852519726832	[277]	[0,0,NaN]	-9	hSpCas9	negative selection	9967507
89328757	89328780	15	-	27869803	HPAFII	viability after 35 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-5.711776419712697	[346]	[0,5,NaN]	-9	hSpCas9	negative selection	9967508
89328942	89328965	15	-	27869803	HPAFII	viability after 35 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-5.850801461168067	[113]	[0,0,NaN]	-9	hSpCas9	negative selection	9967509
89330239	89330262	15	+	27869803	HPAFII	viability after 35 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-4.541473403060339	[45]	[0,0,NaN]	-9	hSpCas9	negative selection	9967510
89333479	89333502	15	-	27869803	HPAFII	viability after 35 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	0.42923386651609263	[239]	[307,0,NaN]	2	hSpCas9	negative selection	9967511
89327213	89327236	15	+	27869803	HPAFII	viability after 31 days	ACGACTTCTTCATCTCCCGCTGG	POLG	ENSG00000140521	-2.459410549552588	[111]	[20,0,NaN]	-8	hSpCas9	negative selection	10049955
89328511	89328534	15	-	27869803	HPAFII	viability after 31 days	CCTGATGCAGTACTGTGCCCAGG	POLG	ENSG00000140521	-7.285569873048249	[277]	[0,0,NaN]	-9	hSpCas9	negative selection	10049956
89328757	89328780	15	-	27869803	HPAFII	viability after 31 days	TGCACAGACTTTATGTAGGGGGG	POLG	ENSG00000140521	-7.605420652903003	[346]	[0,0,NaN]	-9	hSpCas9	negative selection	10049957
89328942	89328965	15	-	27869803	HPAFII	viability after 31 days	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-5.435314873935125	[113]	[0,1,NaN]	-9	hSpCas9	negative selection	10049958
89330239	89330262	15	+	27869803	HPAFII	viability after 31 days	AACGCTCTTCCACCAGCCGCTGG	POLG	ENSG00000140521	-4.690190756381755	[45]	[0,0,NaN]	-9	hSpCas9	negative selection	10049959
89333479	89333502	15	-	27869803	HPAFII	viability after 31 days	AGCAAATCTTCGGGCAAGGAGGG	POLG	ENSG00000140521	0.1790784613962051	[239]	[263,30,NaN]	1	hSpCas9	negative selection	10049960
89333298	89333321	15	-	28162770	P31FUJ	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-3.223524390826368	[619]	[77]	-9	hSpCas9	negative selection	10214034
89326691	89326714	15	-	28162770	P31FUJ	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	0.16312647191676077	[113]	[149]	1	hSpCas9	negative selection	10214035
89333457	89333480	15	-	28162770	P31FUJ	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	0.32831355435240983	[60]	[89]	3	hSpCas9	negative selection	10214036
89333351	89333374	15	+	28162770	P31FUJ	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	0.35794264890078364	[331]	[499]	4	hSpCas9	negative selection	10214037
89330178	89330201	15	+	28162770	P31FUJ	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-2.3838681786053755	[341]	[76]	-8	hSpCas9	negative selection	10214038
89329045	89329068	15	+	28162770	P31FUJ	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-1.1717266276626104	[369]	[192]	-7	hSpCas9	negative selection	10214039
89328942	89328965	15	-	28162770	P31FUJ	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.508220334704005	[350]	[144]	-7	hSpCas9	negative selection	10214040
89328761	89328784	15	-	28162770	P31FUJ	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-1.4403976238227463	[193]	[83]	-7	hSpCas9	negative selection	10214041
89327229	89327252	15	-	28162770	P31FUJ	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-3.5058206988207945	[57]	[5]	-9	hSpCas9	negative selection	10214042
89327045	89327068	15	-	28162770	P31FUJ	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-8.40272720585669	[287]	[0]	-9	hSpCas9	negative selection	10214043
89333298	89333321	15	-	28162770	TF1	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10383400
89326691	89326714	15	-	28162770	TF1	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10383401
89333457	89333480	15	-	28162770	TF1	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10383402
89333351	89333374	15	+	28162770	TF1	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	NaN	[NaN]	[504]	1	hSpCas9	negative selection	10383403
89330178	89330201	15	+	28162770	TF1	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10383404
89329045	89329068	15	+	28162770	TF1	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10383405
89328942	89328965	15	-	28162770	TF1	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10383406
89328761	89328784	15	-	28162770	TF1	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	NaN	[NaN]	[115]	1	hSpCas9	negative selection	10383407
89327229	89327252	15	-	28162770	TF1	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10383408
89327045	89327068	15	-	28162770	TF1	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10383409
89333298	89333321	15	-	28162770	SKM1	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-3.209731851305114	[156]	[29]	-9	hSpCas9	negative selection	10552766
89326691	89326714	15	-	28162770	SKM1	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	-2.6293566200796095	[34]	[9]	-9	hSpCas9	negative selection	10552767
89333457	89333480	15	-	28162770	SKM1	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	0.1448314380427953	[21]	[42]	1	hSpCas9	negative selection	10552768
89333351	89333374	15	+	28162770	SKM1	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	1.5103180027119523	[82]	[417]	9	hSpCas9	negative selection	10552769
89330178	89330201	15	+	28162770	SKM1	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-1.2914869813232257	[71]	[51]	-7	hSpCas9	negative selection	10552770
89329045	89329068	15	+	28162770	SKM1	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-2.527716358203772	[136]	[41]	-9	hSpCas9	negative selection	10552771
89328942	89328965	15	-	28162770	SKM1	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.3428338613234463	[65]	[45]	-7	hSpCas9	negative selection	10552772
89328761	89328784	15	-	28162770	SKM1	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	0.010888316142736332	[31]	[56]	0	hSpCas9	negative selection	10552773
89327229	89327252	15	-	28162770	SKM1	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-4.822001698022005	[15]	[0]	-9	hSpCas9	negative selection	10552774
89327045	89327068	15	-	28162770	SKM1	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-3.484966710744435	[75]	[11]	-9	hSpCas9	negative selection	10552775
89333298	89333321	15	-	28162770	SKM1	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-3.209731851305114	[156]	[29]	-9	hSpCas9	negative selection	10722132
89326691	89326714	15	-	28162770	SKM1	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	-2.6293566200796095	[34]	[9]	-9	hSpCas9	negative selection	10722133
89333457	89333480	15	-	28162770	SKM1	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	0.1448314380427953	[21]	[42]	1	hSpCas9	negative selection	10722134
89333351	89333374	15	+	28162770	SKM1	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	1.5103180027119523	[82]	[417]	9	hSpCas9	negative selection	10722135
89330178	89330201	15	+	28162770	SKM1	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-1.2914869813232257	[71]	[51]	-7	hSpCas9	negative selection	10722136
89329045	89329068	15	+	28162770	SKM1	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-2.527716358203772	[136]	[41]	-9	hSpCas9	negative selection	10722137
89328942	89328965	15	-	28162770	SKM1	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.3428338613234463	[65]	[45]	-7	hSpCas9	negative selection	10722138
89328761	89328784	15	-	28162770	SKM1	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	0.010888316142736332	[31]	[56]	0	hSpCas9	negative selection	10722139
89327229	89327252	15	-	28162770	SKM1	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-4.822001698022005	[15]	[0]	-9	hSpCas9	negative selection	10722140
89327045	89327068	15	-	28162770	SKM1	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-3.484966710744435	[75]	[11]	-9	hSpCas9	negative selection	10722141
89333298	89333321	15	-	28162770	PL21	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-1.293933745065467	[568]	[100]	-7	hSpCas9	negative selection	10891498
89326691	89326714	15	-	28162770	PL21	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	0.6651023390998464	[70]	[48]	6	hSpCas9	negative selection	10891499
89333457	89333480	15	-	28162770	PL21	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	-3.3023607260398635	[67]	[2]	-9	hSpCas9	negative selection	10891500
89333351	89333374	15	+	28162770	PL21	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	-0.04086848501447482	[337]	[142]	0	hSpCas9	negative selection	10891501
89330178	89330201	15	+	28162770	PL21	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-0.49400469712029316	[342]	[105]	-4	hSpCas9	negative selection	10891502
89329045	89329068	15	+	28162770	PL21	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-0.10934371403139698	[403]	[162]	-1	hSpCas9	negative selection	10891503
89328942	89328965	15	-	28162770	PL21	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-0.3125086814159458	[213]	[74]	-2	hSpCas9	negative selection	10891504
89328761	89328784	15	-	28162770	PL21	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	0.7455737510238388	[110]	[80]	6	hSpCas9	negative selection	10891505
89327229	89327252	15	-	28162770	PL21	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-4.8442545048691334	[65]	[0]	-9	hSpCas9	negative selection	10891506
89327045	89327068	15	-	28162770	PL21	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-3.0360586063721584	[244]	[12]	-9	hSpCas9	negative selection	10891507
89333298	89333321	15	-	28162770	P31FUJ	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-3.223524390826368	[619]	[77]	-9	hSpCas9	negative selection	11060864
89326691	89326714	15	-	28162770	P31FUJ	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	0.16312647191676077	[113]	[149]	1	hSpCas9	negative selection	11060865
89333457	89333480	15	-	28162770	P31FUJ	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	0.32831355435240983	[60]	[89]	3	hSpCas9	negative selection	11060866
89333351	89333374	15	+	28162770	P31FUJ	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	0.35794264890078364	[331]	[499]	4	hSpCas9	negative selection	11060867
89330178	89330201	15	+	28162770	P31FUJ	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-2.3838681786053755	[341]	[76]	-8	hSpCas9	negative selection	11060868
89329045	89329068	15	+	28162770	P31FUJ	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-1.1717266276626104	[369]	[192]	-7	hSpCas9	negative selection	11060869
89328942	89328965	15	-	28162770	P31FUJ	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.508220334704005	[350]	[144]	-7	hSpCas9	negative selection	11060870
89328761	89328784	15	-	28162770	P31FUJ	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-1.4403976238227463	[193]	[83]	-7	hSpCas9	negative selection	11060871
89327229	89327252	15	-	28162770	P31FUJ	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-3.5058206988207945	[57]	[5]	-9	hSpCas9	negative selection	11060872
89327045	89327068	15	-	28162770	P31FUJ	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-8.40272720585669	[287]	[0]	-9	hSpCas9	negative selection	11060873
89333298	89333321	15	-	28162770	OCIAML5	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-3.2014754021734664	[264]	[51]	-9	hSpCas9	negative selection	11230230
89326691	89326714	15	-	28162770	OCIAML5	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	-0.7039679318748631	[73]	[81]	-4	hSpCas9	negative selection	11230231
89333457	89333480	15	-	28162770	OCIAML5	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	0.3178584305783152	[27]	[62]	2	hSpCas9	negative selection	11230232
89333351	89333374	15	+	28162770	OCIAML5	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	0.9429680795577392	[167]	[582]	7	hSpCas9	negative selection	11230233
89330178	89330201	15	+	28162770	OCIAML5	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-2.42961160002267	[193]	[64]	-8	hSpCas9	negative selection	11230234
89329045	89329068	15	+	28162770	OCIAML5	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-1.165483165895842	[168]	[135]	-6	hSpCas9	negative selection	11230235
89328942	89328965	15	-	28162770	OCIAML5	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.8345791441351558	[163]	[82]	-7	hSpCas9	negative selection	11230236
89328761	89328784	15	-	28162770	OCIAML5	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-1.5074183994765513	[62]	[39]	-7	hSpCas9	negative selection	11230237
89327229	89327252	15	-	28162770	OCIAML5	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-5.852066570863997	[31]	[0]	-9	hSpCas9	negative selection	11230238
89327045	89327068	15	-	28162770	OCIAML5	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-5.981349587808963	[139]	[3]	-9	hSpCas9	negative selection	11230239
89333298	89333321	15	-	28162770	EOL1	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-1.9242667575854375	[1058]	[146]	-8	hSpCas9	negative selection	11399596
89326691	89326714	15	-	28162770	EOL1	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	-0.18397668520763455	[137]	[63]	-1	hSpCas9	negative selection	11399597
89333457	89333480	15	-	28162770	EOL1	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	-0.14125428682521146	[156]	[74]	-1	hSpCas9	negative selection	11399598
89333351	89333374	15	+	28162770	EOL1	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	0.21888824658228123	[622]	[381]	2	hSpCas9	negative selection	11399599
89330178	89330201	15	+	28162770	EOL1	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-0.41775940392166766	[605]	[238]	-3	hSpCas9	negative selection	11399600
89329045	89329068	15	+	28162770	EOL1	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-1.165283638658531	[761]	[178]	-7	hSpCas9	negative selection	11399601
89328942	89328965	15	-	28162770	EOL1	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-2.3025211369753866	[308]	[32]	-8	hSpCas9	negative selection	11399602
89328761	89328784	15	-	28162770	EOL1	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-1.0365632150358706	[182]	[46]	-6	hSpCas9	negative selection	11399603
89327229	89327252	15	-	28162770	EOL1	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-2.8409869747924423	[67]	[4]	-9	hSpCas9	negative selection	11399604
89327045	89327068	15	-	28162770	EOL1	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-3.56730532475914	[359]	[15]	-9	hSpCas9	negative selection	11399605
89333298	89333321	15	-	28162770	MOLM13	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-3.836965199983842	[671]	[33]	-9	hSpCas9	negative selection	11568962
89326691	89326714	15	-	28162770	MOLM13	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	-0.5229506191699453	[156]	[78]	-3	hSpCas9	negative selection	11568963
89333457	89333480	15	-	28162770	MOLM13	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	-1.9154392580069266	[119]	[22]	-7	hSpCas9	negative selection	11568964
89333351	89333374	15	+	28162770	MOLM13	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	1.0630959137625382	[420]	[635]	7	hSpCas9	negative selection	11568965
89330178	89330201	15	+	28162770	MOLM13	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-0.9834899647979853	[401]	[146]	-5	hSpCas9	negative selection	11568966
89329045	89329068	15	+	28162770	MOLM13	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-5.196800311647312	[557]	[10]	-9	hSpCas9	negative selection	11568967
89328942	89328965	15	-	28162770	MOLM13	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-2.706247871184648	[342]	[37]	-8	hSpCas9	negative selection	11568968
89328761	89328784	15	-	28162770	MOLM13	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-3.626628217239711	[204]	[11]	-9	hSpCas9	negative selection	11568969
89327229	89327252	15	-	28162770	MOLM13	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-5.204535960426917	[50]	[0]	-9	hSpCas9	negative selection	11568970
89327045	89327068	15	-	28162770	MOLM13	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-3.556942471435357	[292]	[17]	-8	hSpCas9	negative selection	11568971
89333298	89333321	15	-	28162770	HEL	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-6.5291885223531025	[720]	[4]	-9	hSpCas9	negative selection	11738328
89326691	89326714	15	-	28162770	HEL	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	-1.6791892628870053	[134]	[26]	-7	hSpCas9	negative selection	11738329
89333457	89333480	15	-	28162770	HEL	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	-0.3920265861603196	[83]	[40]	-3	hSpCas9	negative selection	11738330
89333351	89333374	15	+	28162770	HEL	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	0.22025102823630616	[452]	[337]	1	hSpCas9	negative selection	11738331
89330178	89330201	15	+	28162770	HEL	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-0.800707082464241	[358]	[131]	-5	hSpCas9	negative selection	11738332
89329045	89329068	15	+	28162770	HEL	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-1.9452641230408505	[474]	[78]	-8	hSpCas9	negative selection	11738333
89328942	89328965	15	-	28162770	HEL	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.976989086881476	[251]	[40]	-8	hSpCas9	negative selection	11738334
89328761	89328784	15	-	28162770	HEL	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-1.6556024425693896	[181]	[36]	-7	hSpCas9	negative selection	11738335
89327229	89327252	15	-	28162770	HEL	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-5.029686509971139	[50]	[0]	-9	hSpCas9	negative selection	11738336
89327045	89327068	15	-	28162770	HEL	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-4.540482992055414	[217]	[5]	-9	hSpCas9	negative selection	11738337
89333298	89333321	15	-	28162770	MV411	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-3.879266922060415	[558]	[31]	-9	hSpCas9	negative selection	11907694
89326691	89326714	15	-	28162770	MV411	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	-0.8494239884698136	[76]	[35]	-5	hSpCas9	negative selection	11907695
89333457	89333480	15	-	28162770	MV411	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	0.08917546686604294	[76]	[68]	0	hSpCas9	negative selection	11907696
89333351	89333374	15	+	28162770	MV411	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	0.24315019237967728	[336]	[335]	2	hSpCas9	negative selection	11907697
89330178	89330201	15	+	28162770	MV411	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-2.811456138270793	[324]	[38]	-9	hSpCas9	negative selection	11907698
89329045	89329068	15	+	28162770	MV411	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-1.395010444599141	[383]	[122]	-7	hSpCas9	negative selection	11907699
89328942	89328965	15	-	28162770	MV411	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.3164633344105512	[203]	[68]	-7	hSpCas9	negative selection	11907700
89328761	89328784	15	-	28162770	MV411	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-0.12179625888294376	[92]	[71]	-1	hSpCas9	negative selection	11907701
89327229	89327252	15	-	28162770	MV411	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-1.5180971955802014	[16]	[4]	-7	hSpCas9	negative selection	11907702
89327045	89327068	15	-	28162770	MV411	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-1.8885401187361994	[188]	[42]	-8	hSpCas9	negative selection	11907703
89333298	89333321	15	-	28162770	MONOMAC1	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-2.1049186450711224	[363]	[96]	-9	hSpCas9	negative selection	12077060
89326691	89326714	15	-	28162770	MONOMAC1	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	-0.3721235536176448	[69]	[61]	-3	hSpCas9	negative selection	12077061
89333457	89333480	15	-	28162770	MONOMAC1	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	1.1994805642484923	[48]	[128]	9	hSpCas9	negative selection	12077062
89333351	89333374	15	+	28162770	MONOMAC1	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	0.9070130231625689	[233]	[502]	8	hSpCas9	negative selection	12077063
89330178	89330201	15	+	28162770	MONOMAC1	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-0.6633548512820907	[209]	[151]	-5	hSpCas9	negative selection	12077064
89329045	89329068	15	+	28162770	MONOMAC1	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-0.8821635097061419	[245]	[152]	-6	hSpCas9	negative selection	12077065
89328942	89328965	15	-	28162770	MONOMAC1	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.3841223996600491	[147]	[64]	-8	hSpCas9	negative selection	12077066
89328761	89328784	15	-	28162770	MONOMAC1	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-0.8721971567522881	[98]	[61]	-6	hSpCas9	negative selection	12077067
89327229	89327252	15	-	28162770	MONOMAC1	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	1.201512529430721	[21]	[57]	9	hSpCas9	negative selection	12077068
89327045	89327068	15	-	28162770	MONOMAC1	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-0.9429912244530143	[160]	[95]	-6	hSpCas9	negative selection	12077069
89333298	89333321	15	-	28162770	OCIAML2	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-2.8600415168455107	[92]	[70]	-9	hSpCas9	negative selection	12246426
89326691	89326714	15	-	28162770	OCIAML2	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	-1.1487017303547988	[21]	[54]	-6	hSpCas9	negative selection	12246427
89333457	89333480	15	-	28162770	OCIAML2	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	0.17322636453256346	[15]	[99]	1	hSpCas9	negative selection	12246428
89333351	89333374	15	+	28162770	OCIAML2	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	0.858871489350002	[56]	[572]	8	hSpCas9	negative selection	12246429
89330178	89330201	15	+	28162770	OCIAML2	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-1.6366397766810905	[68]	[122]	-7	hSpCas9	negative selection	12246430
89329045	89329068	15	+	28162770	OCIAML2	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-2.2432193291390887	[81]	[95]	-8	hSpCas9	negative selection	12246431
89328942	89328965	15	-	28162770	OCIAML2	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.970200834732673	[40]	[57]	-8	hSpCas9	negative selection	12246432
89328761	89328784	15	-	28162770	OCIAML2	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-0.20473576526912662	[20]	[100]	-2	hSpCas9	negative selection	12246433
89327229	89327252	15	-	28162770	OCIAML2	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-5.4706298252421615	[7]	[0]	-9	hSpCas9	negative selection	12246434
89327045	89327068	15	-	28162770	OCIAML2	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-2.119157454740784	[28]	[36]	-8	hSpCas9	negative selection	12246435
89333298	89333321	15	-	28162770	OCIAML3	viability	GCAGAGCCTGCCCTACCTGGAGG	POLG	ENSG00000140521	-3.50911874273765	[131]	[34]	-9	hSpCas9	negative selection	12415792
89326691	89326714	15	-	28162770	OCIAML3	viability	GGAGTTTCAACAAGATGTCATGG	POLG	ENSG00000140521	0.2639733548034089	[15]	[57]	2	hSpCas9	negative selection	12415793
89333457	89333480	15	-	28162770	OCIAML3	viability	GGAGATGCCTGGCGAGGCCGCGG	POLG	ENSG00000140521	-1.5940076403241632	[19]	[19]	-8	hSpCas9	negative selection	12415794
89333351	89333374	15	+	28162770	OCIAML3	viability	AGGTTGTCCCCGTAGAGGGGCGG	POLG	ENSG00000140521	0.544474313467268	[66]	[294]	5	hSpCas9	negative selection	12415795
89330178	89330201	15	+	28162770	OCIAML3	viability	GCACCAGTAGGGACCTCCAGGGG	POLG	ENSG00000140521	-1.4255019159671853	[112]	[126]	-7	hSpCas9	negative selection	12415796
89329045	89329068	15	+	28162770	OCIAML3	viability	GAAGCTGCTTAGCCCTGAGATGG	POLG	ENSG00000140521	-0.7927875044386605	[100]	[175]	-5	hSpCas9	negative selection	12415797
89328942	89328965	15	-	28162770	OCIAML3	viability	GAAAGCCAGAAGAGGCCCAGCGG	POLG	ENSG00000140521	-1.7639326417664756	[44]	[39]	-8	hSpCas9	negative selection	12415798
89328761	89328784	15	-	28162770	OCIAML3	viability	GAGGTGCACAGACTTTATGTAGG	POLG	ENSG00000140521	-0.12270192139857428	[21]	[60]	-1	hSpCas9	negative selection	12415799
89327229	89327252	15	-	28162770	OCIAML3	viability	GCACTTATGAGGAGCTCCAGCGG	POLG	ENSG00000140521	-1.956577719708871	[8]	[6]	-8	hSpCas9	negative selection	12415800
89327045	89327068	15	-	28162770	OCIAML3	viability	GTAGGTACAAAGAAGACCCCTGG	POLG	ENSG00000140521	-3.130060540564373	[57]	[19]	-9	hSpCas9	negative selection	12415801