Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 11232
• Symbol: POLG2
• Description: DNA polymerase gamma 2, accessory subunit

DataSource: http://genomecrispr.dkfz.de/#!/results/POLG2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
64485804	64485827	17	-	26472758	Jiyoye	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-0.7034686821781191	[148]	[68]	-5	hSpCas9	negative selection	123470
64492693	64492716	17	+	26472758	Jiyoye	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-1.4064114942632453	[115]	[32]	-7	hSpCas9	negative selection	123471
64496844	64496867	17	-	26472758	Jiyoye	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-0.9976663506670819	[187]	[70]	-6	hSpCas9	negative selection	123472
64496824	64496847	17	-	26472758	Jiyoye	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.6290448064068799	[120]	[58]	-4	hSpCas9	negative selection	123473
64496662	64496685	17	+	26472758	Jiyoye	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-1.165241865896169	[228]	[76]	-7	hSpCas9	negative selection	123474
64496611	64496634	17	-	26472758	Jiyoye	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-0.5417504338998573	[221]	[114]	-4	hSpCas9	negative selection	123475
64496584	64496607	17	-	26472758	Jiyoye	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-0.7854696964365226	[15]	[6]	-5	hSpCas9	negative selection	123476
64496554	64496577	17	+	26472758	Jiyoye	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-1.788611683248405	[196]	[42]	-8	hSpCas9	negative selection	123477
64496538	64496561	17	+	26472758	Jiyoye	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-0.10061925869282301	[90]	[63]	0	hSpCas9	negative selection	123478
64492710	64492733	17	+	26472758	Jiyoye	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-1.0202458422288028	[233]	[86]	-6	hSpCas9	negative selection	123479
64485804	64485827	17	-	26472758	KBM7	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-2.265104071306207	[416,292]	[47,21]	-8	hSpCas9	negative selection	314588
64492693	64492716	17	+	26472758	KBM7	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-3.150799713542098	[453,465]	[14,32]	-9	hSpCas9	negative selection	314589
64496844	64496867	17	-	26472758	KBM7	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-1.9056756394802008	[539,273]	[37,59]	-8	hSpCas9	negative selection	314590
64496824	64496847	17	-	26472758	KBM7	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.7873308629231838	[273,328]	[86,79]	-6	hSpCas9	negative selection	314591
64496662	64496685	17	+	26472758	KBM7	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-1.2819314808140798	[618,344]	[91,89]	-7	hSpCas9	negative selection	314592
64496611	64496634	17	-	26472758	KBM7	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-1.1822491350952649	[911,687]	[103,217]	-7	hSpCas9	negative selection	314593
64496584	64496607	17	-	26472758	KBM7	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-2.7507414674737403	[16,11]	[0,0]	-9	hSpCas9	negative selection	314594
64496554	64496577	17	+	26472758	KBM7	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-3.345975627130426	[1024,776]	[35,45]	-9	hSpCas9	negative selection	314595
64496538	64496561	17	+	26472758	KBM7	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-0.7421278866972911	[466,422]	[170,83]	-6	hSpCas9	negative selection	314596
64492710	64492733	17	+	26472758	KBM7	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-2.5293836447550317	[852,523]	[45,62]	-9	hSpCas9	negative selection	314597
64485804	64485827	17	-	26472758	Raji	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	0.3403607073512135	[193]	[56]	3	hSpCas9	negative selection	505706
64492693	64492716	17	+	26472758	Raji	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	1.0320954080693623	[117]	[55]	8	hSpCas9	negative selection	505707
64496844	64496867	17	-	26472758	Raji	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-0.4692636971355531	[172]	[28]	-4	hSpCas9	negative selection	505708
64496824	64496847	17	-	26472758	Raji	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	1.2353911477496708	[96]	[52]	9	hSpCas9	negative selection	505709
64496662	64496685	17	+	26472758	Raji	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-0.17272438381913593	[271]	[55]	-1	hSpCas9	negative selection	505710
64496611	64496634	17	-	26472758	Raji	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-0.8332379175474688	[475]	[61]	-6	hSpCas9	negative selection	505711
64496584	64496607	17	-	26472758	Raji	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-0.008093682046337314	[12]	[2]	0	hSpCas9	negative selection	505712
64496554	64496577	17	+	26472758	Raji	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-1.020569195593397	[541]	[61]	-6	hSpCas9	negative selection	505713
64496538	64496561	17	+	26472758	Raji	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-0.12868382285992483	[211]	[44]	-1	hSpCas9	negative selection	505714
64492710	64492733	17	+	26472758	Raji	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-0.6370250419781687	[582]	[86]	-5	hSpCas9	negative selection	505715
64485804	64485827	17	-	26472758	K562	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-1.539852581278116	[371]	[107]	-6	hSpCas9	negative selection	696824
64492693	64492716	17	+	26472758	K562	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-1.429137696323698	[318]	[99]	-6	hSpCas9	negative selection	696825
64496844	64496867	17	-	26472758	K562	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-0.7798288185802305	[239]	[117]	-4	hSpCas9	negative selection	696826
64496824	64496847	17	-	26472758	K562	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.1862156266634155	[216]	[160]	-1	hSpCas9	negative selection	696827
64496662	64496685	17	+	26472758	K562	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	0.20023380065823146	[430]	[417]	1	hSpCas9	negative selection	696828
64496611	64496634	17	-	26472758	K562	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	0.47092725747512665	[699]	[818]	4	hSpCas9	negative selection	696829
64496584	64496607	17	-	26472758	K562	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-1.7555812723335524	[3]	[0]	-7	hSpCas9	negative selection	696830
64496554	64496577	17	+	26472758	K562	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-0.2272495634897479	[813]	[586]	-1	hSpCas9	negative selection	696831
64496538	64496561	17	+	26472758	K562	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-0.9426117507785231	[402]	[176]	-5	hSpCas9	negative selection	696832
64492710	64492733	17	+	26472758	K562	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-1.857009005225676	[544]	[126]	-7	hSpCas9	negative selection	696833
64485754	64485777	17	+	26627737	DLD1	viability	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	0.4048047023683259	[103]	[37,22,63]	4	hSpCas9	negative selection	799350
64490951	64490974	17	+	26627737	DLD1	viability	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-2.9930593913331975	[704]	[5,20,51]	-9	hSpCas9	negative selection	799351
64492676	64492699	17	-	26627737	DLD1	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.6005959949130293	[200]	[14,0,41]	-8	hSpCas9	negative selection	799352
64492941	64492964	17	+	26627737	DLD1	viability	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-3.4971617659150582	[428]	[6,11,15]	-9	hSpCas9	negative selection	799353
64496620	64496643	17	+	26627737	DLD1	viability	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-6.095644432954684	[285]	[0,1,0]	-9	hSpCas9	negative selection	799354
64496658	64496681	17	+	26627737	DLD1	viability	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.23072035552165482	[705]	[215,385,190]	2	hSpCas9	negative selection	799355
64485754	64485777	17	+	26627737	GBM cells	viability after 5 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	-0.6271549367819023	[107]	[31,42]	-7	hSpCas9	negative selection	881665
64490951	64490974	17	+	26627737	GBM cells	viability after 5 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	0.14823140196497153	[545]	[300,347]	2	hSpCas9	negative selection	881666
64492676	64492699	17	-	26627737	GBM cells	viability after 5 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	0.13641318861234164	[94]	[69,41]	2	hSpCas9	negative selection	881667
64492941	64492964	17	+	26627737	GBM cells	viability after 5 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.07675679575257394	[293]	[142,155]	-1	hSpCas9	negative selection	881668
64496620	64496643	17	+	26627737	GBM cells	viability after 5 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-0.20492193609885434	[143]	[70,62]	-3	hSpCas9	negative selection	881669
64496658	64496681	17	+	26627737	GBM cells	viability after 5 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.6768610310583703	[353]	[261,344]	8	hSpCas9	negative selection	881670
64485754	64485777	17	+	26627737	GBM cells	viability after 13 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	-1.0941274265322907	[107]	[27,26]	-8	hSpCas9	negative selection	963980
64490951	64490974	17	+	26627737	GBM cells	viability after 13 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-0.3684423479355753	[545]	[218,237]	-4	hSpCas9	negative selection	963981
64492676	64492699	17	-	26627737	GBM cells	viability after 13 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.1241636348239112	[94]	[5,37]	-8	hSpCas9	negative selection	963982
64492941	64492964	17	+	26627737	GBM cells	viability after 13 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.04233479800500131	[293]	[171,140]	0	hSpCas9	negative selection	963983
64496620	64496643	17	+	26627737	GBM cells	viability after 13 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-0.5208058849425745	[143]	[70,40]	-6	hSpCas9	negative selection	963984
64496658	64496681	17	+	26627737	GBM cells	viability after 13 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.4573639677131285	[353]	[330,208]	6	hSpCas9	negative selection	963985
64485754	64485777	17	+	26627737	GBM cells	viability after 21 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	-2.533617284712743	[107]	[6,12]	-9	hSpCas9	negative selection	1046295
64490951	64490974	17	+	26627737	GBM cells	viability after 21 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-1.4853597144337503	[545]	[118,93]	-8	hSpCas9	negative selection	1046296
64492676	64492699	17	-	26627737	GBM cells	viability after 21 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.270832674575338	[94]	[23,18]	-8	hSpCas9	negative selection	1046297
64492941	64492964	17	+	26627737	GBM cells	viability after 21 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.4943035796302992	[293]	[115,110]	-4	hSpCas9	negative selection	1046298
64496620	64496643	17	+	26627737	GBM cells	viability after 21 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-0.8593320803708808	[143]	[51,34]	-6	hSpCas9	negative selection	1046299
64496658	64496681	17	+	26627737	GBM cells	viability after 21 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.4181275466800356	[353]	[280,234]	4	hSpCas9	negative selection	1046300
64485754	64485777	17	+	26627737	RPE1	viability after 9 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	1.4523375331864394	[51]	[37,52]	7	hSpCas9	negative selection	1128610
64490951	64490974	17	+	26627737	RPE1	viability after 9 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-0.04669210569090332	[2320]	[451,1027]	0	hSpCas9	negative selection	1128611
64492676	64492699	17	-	26627737	RPE1	viability after 9 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	0.2597448373679261	[203]	[89,58]	1	hSpCas9	negative selection	1128612
64492941	64492964	17	+	26627737	RPE1	viability after 9 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.4842433924374407	[909]	[159,259]	-3	hSpCas9	negative selection	1128613
64496620	64496643	17	+	26627737	RPE1	viability after 9 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	2.154076022333161	[118]	[136,202]	9	hSpCas9	negative selection	1128614
64496658	64496681	17	+	26627737	RPE1	viability after 9 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	-0.035219867286666595	[992]	[274,339]	0	hSpCas9	negative selection	1128615
64485754	64485777	17	+	26627737	RPE1	viability after 12 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	1.1749131333652483	[51]	[15,47]	7	hSpCas9	negative selection	1210925
64490951	64490974	17	+	26627737	RPE1	viability after 12 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	0.16059545019707855	[2320]	[475,930]	1	hSpCas9	negative selection	1210926
64492676	64492699	17	-	26627737	RPE1	viability after 12 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	0.17655209411054718	[203]	[110,9]	1	hSpCas9	negative selection	1210927
64492941	64492964	17	+	26627737	RPE1	viability after 12 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.3777075437625398	[909]	[244,127]	-3	hSpCas9	negative selection	1210928
64496620	64496643	17	+	26627737	RPE1	viability after 12 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	2.0169874554703395	[118]	[176,78]	8	hSpCas9	negative selection	1210929
64496658	64496681	17	+	26627737	RPE1	viability after 12 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.2681745278649766	[992]	[279,364]	1	hSpCas9	negative selection	1210930
64485754	64485777	17	+	26627737	RPE1	viability after 15 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	1.6477065982369048	[51]	[40,50]	8	hSpCas9	negative selection	1293240
64490951	64490974	17	+	26627737	RPE1	viability after 15 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-0.10522318640266892	[2320]	[335,874]	0	hSpCas9	negative selection	1293241
64492676	64492699	17	-	26627737	RPE1	viability after 15 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.14066483473669833	[203]	[60,43]	-1	hSpCas9	negative selection	1293242
64492941	64492964	17	+	26627737	RPE1	viability after 15 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.6087563603313098	[909]	[235,103]	-4	hSpCas9	negative selection	1293243
64496620	64496643	17	+	26627737	RPE1	viability after 15 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	0.8912000963349627	[118]	[37,85]	5	hSpCas9	negative selection	1293244
64496658	64496681	17	+	26627737	RPE1	viability after 15 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	-0.030826885744070387	[992]	[220,326]	0	hSpCas9	negative selection	1293245
64485754	64485777	17	+	26627737	RPE1	viability after 18 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	0.0685069063603092	[51]	[20,7]	0	hSpCas9	negative selection	1375555
64490951	64490974	17	+	26627737	RPE1	viability after 18 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-0.3781008862799007	[2320]	[334,638]	-2	hSpCas9	negative selection	1375556
64492676	64492699	17	-	26627737	RPE1	viability after 18 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.2697873193948548	[203]	[64,24]	-2	hSpCas9	negative selection	1375557
64492941	64492964	17	+	26627737	RPE1	viability after 18 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.3294319347671138	[909]	[222,165]	-2	hSpCas9	negative selection	1375558
64496620	64496643	17	+	26627737	RPE1	viability after 18 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-0.22889579843733676	[118]	[9,45]	-1	hSpCas9	negative selection	1375559
64496658	64496681	17	+	26627737	RPE1	viability after 18 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	-0.16037363750817155	[992]	[218,261]	-1	hSpCas9	negative selection	1375560
64485754	64485777	17	+	26627737	HeLa	viability after 8 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	0.6171996949005658	[120]	[101,49,93]	5	hSpCas9	negative selection	1457870
64490951	64490974	17	+	26627737	HeLa	viability after 8 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-0.03158253373013897	[825]	[264,302,459]	0	hSpCas9	negative selection	1457871
64492676	64492699	17	-	26627737	HeLa	viability after 8 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.24242189576634476	[229]	[135,27,99]	-2	hSpCas9	negative selection	1457872
64492941	64492964	17	+	26627737	HeLa	viability after 8 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.057656974824695464	[425]	[249,119,179]	0	hSpCas9	negative selection	1457873
64496620	64496643	17	+	26627737	HeLa	viability after 8 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	0.10760576225858087	[268]	[154,107,121]	1	hSpCas9	negative selection	1457874
64496658	64496681	17	+	26627737	HeLa	viability after 8 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.4380731537922814	[703]	[425,354,462]	4	hSpCas9	negative selection	1457875
64485754	64485777	17	+	26627737	HeLa	viability after 12 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	-0.10712339587416198	[120]	[29,53,53]	-1	hSpCas9	negative selection	1540185
64490951	64490974	17	+	26627737	HeLa	viability after 12 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	0.18585527935328794	[825]	[376,383,403]	1	hSpCas9	negative selection	1540186
64492676	64492699	17	-	26627737	HeLa	viability after 12 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.30200956754630426	[229]	[167,0,72]	-3	hSpCas9	negative selection	1540187
64492941	64492964	17	+	26627737	HeLa	viability after 12 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.007065547186262289	[425]	[136,188,196]	0	hSpCas9	negative selection	1540188
64496620	64496643	17	+	26627737	HeLa	viability after 12 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-0.2932241300976264	[268]	[16,156,88]	-3	hSpCas9	negative selection	1540189
64496658	64496681	17	+	26627737	HeLa	viability after 12 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.8815774023367152	[703]	[559,580,462]	6	hSpCas9	negative selection	1540190
64485754	64485777	17	+	26627737	HeLa	viability after 15 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	0.6421747771483315	[120]	[36,106,87]	5	hSpCas9	negative selection	1622500
64490951	64490974	17	+	26627737	HeLa	viability after 15 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	0.4883991750929815	[825]	[439,402,580]	4	hSpCas9	negative selection	1622501
64492676	64492699	17	-	26627737	HeLa	viability after 15 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.0688421912996677	[229]	[49,0,85]	-7	hSpCas9	negative selection	1622502
64492941	64492964	17	+	26627737	HeLa	viability after 15 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	0.09023928881617187	[425]	[129,282,137]	0	hSpCas9	negative selection	1622503
64496620	64496643	17	+	26627737	HeLa	viability after 15 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-0.16036020550393848	[268]	[124,53,115]	-1	hSpCas9	negative selection	1622504
64496658	64496681	17	+	26627737	HeLa	viability after 15 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.880633001132178	[703]	[550,488,543]	6	hSpCas9	negative selection	1622505
64485754	64485777	17	+	26627737	HeLa	viability after 18 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	0.6507856352357344	[120]	[22,91,87]	5	hSpCas9	negative selection	1704815
64490951	64490974	17	+	26627737	HeLa	viability after 18 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	0.5299597759088679	[825]	[308,349,580]	4	hSpCas9	negative selection	1704816
64492676	64492699	17	-	26627737	HeLa	viability after 18 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.092477553604836	[229]	[31,0,85]	-7	hSpCas9	negative selection	1704817
64492941	64492964	17	+	26627737	HeLa	viability after 18 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	0.08665627198616112	[425]	[80,240,137]	0	hSpCas9	negative selection	1704818
64496620	64496643	17	+	26627737	HeLa	viability after 18 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-0.11155525173797265	[268]	[86,48,115]	-1	hSpCas9	negative selection	1704819
64496658	64496681	17	+	26627737	HeLa	viability after 18 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.8954181607700565	[703]	[376,408,543]	6	hSpCas9	negative selection	1704820
64485754	64485777	17	+	26627737	HCT116	viability after 6 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	0.23120926391005336	[172]	[87,0]	1	hSpCas9	negative selection	1787130
64490951	64490974	17	+	26627737	HCT116	viability after 6 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-0.603720935915717	[1221]	[157,108]	-3	hSpCas9	negative selection	1787131
64492676	64492699	17	-	26627737	HCT116	viability after 6 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-2.1492812571607898	[288]	[26,0]	-8	hSpCas9	negative selection	1787132
64492941	64492964	17	+	26627737	HCT116	viability after 6 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	0.36049097539573377	[449]	[211,23]	2	hSpCas9	negative selection	1787133
64496620	64496643	17	+	26627737	HCT116	viability after 6 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	0.5252587083572549	[478]	[128,96]	3	hSpCas9	negative selection	1787134
64496658	64496681	17	+	26627737	HCT116	viability after 6 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	2.364147281517515	[768]	[1362,213]	9	hSpCas9	negative selection	1787135
64485754	64485777	17	+	26627737	HCT116	viability after 8 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	-0.5510701023124586	[201]	[61,117,47]	-6	hSpCas9	negative selection	1869445
64490951	64490974	17	+	26627737	HCT116	viability after 8 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	0.3149989757605385	[460]	[255,378,311]	3	hSpCas9	negative selection	1869446
64492676	64492699	17	-	26627737	HCT116	viability after 8 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	0.07208719868422975	[118]	[76,65,63]	0	hSpCas9	negative selection	1869447
64492941	64492964	17	+	26627737	HCT116	viability after 8 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	0.43444145355287556	[194]	[87,151,193]	4	hSpCas9	negative selection	1869448
64496620	64496643	17	+	26627737	HCT116	viability after 8 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	0.90179741255804	[151]	[174,154,139]	7	hSpCas9	negative selection	1869449
64496658	64496681	17	+	26627737	HCT116	viability after 8 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.8733937661331442	[320]	[359,308,303]	7	hSpCas9	negative selection	1869450
64485754	64485777	17	+	26627737	HCT116	viability after 9 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	-0.33607975833720927	[172]	[49,25]	-2	hSpCas9	negative selection	1951760
64490951	64490974	17	+	26627737	HCT116	viability after 9 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-0.35217269763640635	[1221]	[325,199]	-2	hSpCas9	negative selection	1951761
64492676	64492699	17	-	26627737	HCT116	viability after 9 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.5011554652805792	[288]	[101,16]	-4	hSpCas9	negative selection	1951762
64492941	64492964	17	+	26627737	HCT116	viability after 9 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	1.2514889034024335	[449]	[332,248]	8	hSpCas9	negative selection	1951763
64496620	64496643	17	+	26627737	HCT116	viability after 9 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	0.5934303100423162	[478]	[154,222]	4	hSpCas9	negative selection	1951764
64496658	64496681	17	+	26627737	HCT116	viability after 9 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	1.6198933715789394	[768]	[672,597]	8	hSpCas9	negative selection	1951765
64485754	64485777	17	+	26627737	HCT116	viability after 12 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	-0.3028959609890348	[201]	[56,97,105]	-3	hSpCas9	negative selection	2034075
64490951	64490974	17	+	26627737	HCT116	viability after 12 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	0.20002124429419865	[460]	[293,215,321]	2	hSpCas9	negative selection	2034076
64492676	64492699	17	-	26627737	HCT116	viability after 12 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.6947514164388193	[118]	[28,14,12]	-9	hSpCas9	negative selection	2034077
64492941	64492964	17	+	26627737	HCT116	viability after 12 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	0.45479567128852416	[194]	[163,86,166]	4	hSpCas9	negative selection	2034078
64496620	64496643	17	+	26627737	HCT116	viability after 12 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	0.8674072228223374	[151]	[99,136,203]	7	hSpCas9	negative selection	2034079
64496658	64496681	17	+	26627737	HCT116	viability after 12 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.632658428678169	[320]	[234,303,248]	6	hSpCas9	negative selection	2034080
64485754	64485777	17	+	26627737	HCT116	viability after 15 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	-0.8144263254847998	[201]	[61,34,99]	-7	hSpCas9	negative selection	2116390
64490951	64490974	17	+	26627737	HCT116	viability after 15 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-0.28698622993583806	[460]	[224,213,212]	-3	hSpCas9	negative selection	2116391
64492676	64492699	17	-	26627737	HCT116	viability after 15 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-3.4010326486703146	[118]	[18,0,0]	-9	hSpCas9	negative selection	2116392
64492941	64492964	17	+	26627737	HCT116	viability after 15 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	0.559207386185342	[194]	[123,114,249]	5	hSpCas9	negative selection	2116393
64496620	64496643	17	+	26627737	HCT116	viability after 15 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	0.4537121366540052	[151]	[118,153,85]	4	hSpCas9	negative selection	2116394
64496658	64496681	17	+	26627737	HCT116	viability after 15 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.9335557378339514	[320]	[356,355,343]	7	hSpCas9	negative selection	2116395
64485754	64485777	17	+	26627737	HCT116	viability after 18 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	-1.0942670428255479	[201]	[14,25,99]	-7	hSpCas9	negative selection	2198705
64490951	64490974	17	+	26627737	HCT116	viability after 18 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-0.3390064266080836	[460]	[137,196,192]	-3	hSpCas9	negative selection	2198706
64492676	64492699	17	-	26627737	HCT116	viability after 18 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-5.113115495357175	[118]	[2,0,0]	-9	hSpCas9	negative selection	2198707
64492941	64492964	17	+	26627737	HCT116	viability after 18 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	0.654501398966366	[194]	[109,139,197]	5	hSpCas9	negative selection	2198708
64496620	64496643	17	+	26627737	HCT116	viability after 18 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-0.02950901437685105	[151]	[67,64,83]	0	hSpCas9	negative selection	2198709
64496658	64496681	17	+	26627737	HCT116	viability after 18 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.5516766595562729	[320]	[98,240,346]	4	hSpCas9	negative selection	2198710
64494969	64494992	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGACCATCCTGGCTAACAAGG	POLG2	ENSG00000256525	-1.1174807317499718	[30,74]	[4,4]	-6	dCas9-VP64	positive selection	2405372
64478618	64478641	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGTCACCACGCCCAG	POLG2	ENSG00000256525	3.599242638299855	[15,27]	[106,7]	9	dCas9-VP64	positive selection	2467151
64494969	64494992	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGACCATCCTGGCTAACAAGG	POLG2	ENSG00000256525	-0.3866569806865121	[139,148]	[35,34]	-4	dCas9-VP64	positive selection	2500627
64478618	64478641	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGTCACCACGCCCAG	POLG2	ENSG00000256525	-1.0056755342139323	[143,43]	[19,9]	-8	dCas9-VP64	positive selection	2562406
64496824	64496847	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.1674902375824221	[4,3]	[3,2]	-2	hSpCas9	positive selection	3012408
64492975	64492998	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCTGGATCTGGTAAACAAGAGG	POLG2	ENSG00000256525	-1.8911143703146724	[3,3]	[0,0]	-9	hSpCas9	positive selection	3012409
64496772	64496795	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTCCCTCTCCAGACCCGGGGG	POLG2	ENSG00000256525	-0.7996830801471173	[2,2]	[1,0]	-8	hSpCas9	positive selection	3012410
64496885	64496908	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGGGGGTCGAGTAGATGCGGGG	POLG2	ENSG00000256525	0.2916029755003758	[4,4]	[3,5]	6	hSpCas9	positive selection	3012411
64496824	64496847	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.5169823775540914	[4,4]	[1,1]	-7	hSpCas9	positive selection	3080266
64492975	64492998	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCTGGATCTGGTAAACAAGAGG	POLG2	ENSG00000256525	0.03706130849664609	[3,3]	[1,2]	0	hSpCas9	positive selection	3080267
64496772	64496795	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTCCCTCTCCAGACCCGGGGG	POLG2	ENSG00000256525	-0.7759872315237686	[2,2]	[0,0]	-9	hSpCas9	positive selection	3080268
64496885	64496908	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGGGGGTCGAGTAGATGCGGGG	POLG2	ENSG00000256525	-0.4361282806533162	[4,4]	[2,1]	-6	hSpCas9	positive selection	3080269
64492941	64492964		+	24336571	A375	resistance to PLX after 7 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.16826343985284875	[7,10]	[6,8]	-5	hSpCas9	positive selection	3136699
64492739	64492762		-	24336571	A375	resistance to PLX after 7 days	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.03816058772300068	[7,8]	[7,8]	-1	hSpCas9	positive selection	3136700
64492676	64492699		-	24336571	A375	resistance to PLX after 7 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	0.4772145232087285	[4,4]	[6,6]	9	hSpCas9	positive selection	3136701
64492941	64492964		+	24336571	A375	resistance to PLX after 14 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	0.17589514955851537	[7,4]	[2,3]	1	hSpCas9	positive selection	3194492
64492739	64492762		-	24336571	A375	resistance to PLX after 14 days	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	1.2511926584779438	[4,5]	[7,4]	8	hSpCas9	positive selection	3194493
64492676	64492699		-	24336571	A375	resistance to PLX after 14 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	1.4432660045579853	[1,3]	[5,1]	8	hSpCas9	positive selection	3194494
64492941	64492964		+	24336571	A375	viability after 7 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.6572379561456343	[15]	[7,10]	-7	hSpCas9	negative selection	3252285
64492739	64492762		-	24336571	A375	viability after 7 days	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.2946704870696999	[6]	[7,8]	4	hSpCas9	negative selection	3252286
64492676	64492699		-	24336571	A375	viability after 7 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.7487349164744995	[8]	[4,4]	-8	hSpCas9	negative selection	3252287
64492941	64492964		+	24336571	A375	viability after 14 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-1.1118583195632243	[15]	[7,4]	-8	hSpCas9	negative selection	3310078
64492739	64492762		-	24336571	A375	viability after 14 days	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.2575657332511655	[6]	[4,5]	-3	hSpCas9	negative selection	3310079
64492676	64492699		-	24336571	A375	viability after 14 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.3581062665708297	[8]	[1,3]	-9	hSpCas9	negative selection	3310080
64492904	64492927	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	3.169863370195496	[16,16]	[0,0]	8	hSpCas9	positive selection	3386668
64485844	64485867	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	2.00939869800225	[37,37]	[0,0]	7	hSpCas9	positive selection	3386669
64490828	64490851	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	1.8997742068277512	[163,163]	[3,3]	7	hSpCas9	positive selection	3386670
64496824	64496847	17	-	26780180	HT29	viability (Avana library 4 designs)	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	3.60187731905294	[]	[]	9	hSpCas9	negative selection	3450517
64492975	64492998	17	-	26780180	HT29	viability (Avana library 4 designs)	GCCTGGATCTGGTAAACAAGAGG	POLG2	ENSG00000256525	3.89499755097967	[]	[]	9	hSpCas9	negative selection	3450518
64496771	64496794	17	+	26780180	HT29	viability (Avana library 4 designs)	GCTTCCCTCTCCAGACCCGGGGG	POLG2	ENSG00000256525	2.45396531149852	[]	[]	8	hSpCas9	negative selection	3450519
64496885	64496908	17	-	26780180	HT29	viability (Avana library 4 designs)	TTGGGGGTCGAGTAGATGCGGGG	POLG2	ENSG00000256525	2.67567081095589	[]	[]	8	hSpCas9	negative selection	3450520
64496885	64496908	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGGGGGTCGAGTAGATGCGGGG	POLG2	ENSG00000256525	-2.66305823101383	[]	[]	-3	hSpCas9	negative selection	3545801
64496771	64496794	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCCCTCTCCAGACCCGGGGG	POLG2	ENSG00000256525	-8.06137275863682	[]	[]	-7	hSpCas9	negative selection	3545802
64496824	64496847	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-2.5225899384983	[]	[]	-3	hSpCas9	negative selection	3545803
64492975	64492998	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTGGATCTGGTAAACAAGAGG	POLG2	ENSG00000256525	-10.0658321837192	[]	[]	-7	hSpCas9	negative selection	3545804
64496786	64496809	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGAGCACCCAGAAGCCCCCGGG	POLG2	ENSG00000256525	-2.02954404528139	[]	[]	-2	hSpCas9	negative selection	3545805
64496843	64496866	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAAGGAGTAGCCCCAAAGGAGGG	POLG2	ENSG00000256525	-4.34957927560364	[]	[]	-5	hSpCas9	negative selection	3545806
64496885	64496908	17	-	26780180	A375	viability (Avana lentiGuide)	TTGGGGGTCGAGTAGATGCGGGG	POLG2	ENSG00000256525	7.29692601488113	[]	[]	6	hSpCas9	negative selection	3654460
64496771	64496794	17	+	26780180	A375	viability (Avana lentiGuide)	GCTTCCCTCTCCAGACCCGGGGG	POLG2	ENSG00000256525	15.6681950238525	[]	[]	8	hSpCas9	negative selection	3654461
64496824	64496847	17	-	26780180	A375	viability (Avana lentiGuide)	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	17.7485780656644	[]	[]	8	hSpCas9	negative selection	3654462
64492975	64492998	17	-	26780180	A375	viability (Avana lentiGuide)	GCCTGGATCTGGTAAACAAGAGG	POLG2	ENSG00000256525	5.32050802526133	[]	[]	5	hSpCas9	negative selection	3654463
64496786	64496809	17	-	26780180	A375	viability (Avana lentiGuide)	GCGAGCACCCAGAAGCCCCCGGG	POLG2	ENSG00000256525	17.2251863402615	[]	[]	8	hSpCas9	negative selection	3654464
64496843	64496866	17	-	26780180	A375	viability (Avana lentiGuide)	AAAGGAGTAGCCCCAAAGGAGGG	POLG2	ENSG00000256525	9.46308991304819	[]	[]	6	hSpCas9	negative selection	3654465
64496885	64496908	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGGGGGTCGAGTAGATGCGGGG	POLG2	ENSG00000256525	0.20566154201607886	[5]	[6,6]	6	hSpCas9	positive selection	3763119
64496771	64496794	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCCCTCTCCAGACCCGGGGG	POLG2	ENSG00000256525	-0.1122516477043477	[3]	[3,2]	-2	hSpCas9	positive selection	3763120
64496824	64496847	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	0.21740783004938963	[5]	[6,5]	6	hSpCas9	positive selection	3763121
64492975	64492998	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTGGATCTGGTAAACAAGAGG	POLG2	ENSG00000256525	0.09510258347797172	[5]	[5,4]	2	hSpCas9	positive selection	3763122
64496786	64496809	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGAGCACCCAGAAGCCCCCGGG	POLG2	ENSG00000256525	0.24315673694173756	[4]	[5,5]	7	hSpCas9	positive selection	3763123
64496843	64496866	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAAGGAGTAGCCCCAAAGGAGGG	POLG2	ENSG00000256525	0.13559195120887466	[5]	[6,5]	3	hSpCas9	positive selection	3763124
64496885	64496908	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGGGGGTCGAGTAGATGCGGGG	POLG2	ENSG00000256525	-0.06442018730151775	[6]	[4,5]	-1	hSpCas9	positive selection	3871726
64496771	64496794	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCCCTCTCCAGACCCGGGGG	POLG2	ENSG00000256525	-1.230594882736738	[4]	[1,0]	-9	hSpCas9	positive selection	3871727
64496824	64496847	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.46556615973006765	[6]	[2,3]	-6	hSpCas9	positive selection	3871728
64492975	64492998	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTGGATCTGGTAAACAAGAGG	POLG2	ENSG00000256525	0.21083917965126542	[5]	[5,5]	5	hSpCas9	positive selection	3871729
64496786	64496809	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGAGCACCCAGAAGCCCCCGGG	POLG2	ENSG00000256525	0.05316249710652948	[6]	[5,5]	1	hSpCas9	positive selection	3871730
64496843	64496866	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAAGGAGTAGCCCCAAAGGAGGG	POLG2	ENSG00000256525	0.028115755139007145	[5]	[4,4]	0	hSpCas9	positive selection	3871731
64492739	64492762	17	-	26780180	A375	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	1.5110857494784	[]	[]	8	hSpCas9	negative selection	3982556
64485844	64485867	17	-	26780180	A375	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	1.06656448285554	[]	[]	5	hSpCas9	negative selection	3982557
64492904	64492927	17	-	26780180	A375	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	0.714806522434009	[]	[]	2	hSpCas9	negative selection	3982558
64485796	64485819	17	-	26780180	A375	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	2.09043538532297	[]	[]	9	hSpCas9	negative selection	3982559
64492676	64492699	17	-	26780180	A375	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	0.684550404065501	[]	[]	2	hSpCas9	negative selection	3982560
64490828	64490851	17	+	26780180	A375	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	1.81942446794346	[]	[]	9	hSpCas9	negative selection	3982561
64492739	64492762	17	-	26780180	HT29	viability (GeCKOv2 library)	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.531286449178368	[]	[]	1	hSpCas9	negative selection	4090522
64485844	64485867	17	-	26780180	HT29	viability (GeCKOv2 library)	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.737575146416903	[]	[]	3	hSpCas9	negative selection	4090523
64492904	64492927	17	-	26780180	HT29	viability (GeCKOv2 library)	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	0.785405987430564	[]	[]	3	hSpCas9	negative selection	4090524
64485796	64485819	17	-	26780180	HT29	viability (GeCKOv2 library)	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	2.58770114838269	[]	[]	9	hSpCas9	negative selection	4090525
64492676	64492699	17	-	26780180	HT29	viability (GeCKOv2 library)	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	0.855306102528664	[]	[]	3	hSpCas9	negative selection	4090526
64490828	64490851	17	+	26780180	HT29	viability (GeCKOv2 library)	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	2.00136422662357	[]	[]	9	hSpCas9	negative selection	4090527
64492941	64492964	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.5779140036570938	[3]	[0,1]	-9	hSpCas9	positive selection	4161749
64492739	64492762	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.04480207785446052	[3]	[1,2]	1	hSpCas9	positive selection	4161750
64492676	64492699	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.19897805983237063	[3]	[1,1]	-5	hSpCas9	positive selection	4161751
64492941	64492964	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	1.701929075680748	[2]	[2,4,4,4]	9	hSpCas9	positive selection	4225771
64492739	64492762	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	1.574062677143317	[2]	[1,0,4,3]	9	hSpCas9	positive selection	4225772
64492676	64492699	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.2336964317173775	[3]	[1,1,0,0]	-3	hSpCas9	positive selection	4225773
64492676	64492699	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.0714179035581779	[0]	[0,0]	-1	hSpCas9	positive selection	4291174
64492739	64492762	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.388428451288151	[2]	[1,2]	7	hSpCas9	positive selection	4291175
64485796	64485819	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.18685337070115382	[2]	[2,1]	-4	hSpCas9	positive selection	4291176
64492904	64492927	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.04573888121149772	[1]	[1,0]	-1	hSpCas9	positive selection	4355423
64485844	64485867	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.42335824290260893	[1]	[1,0]	-7	hSpCas9	positive selection	4355424
64490828	64490851	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	0.634132440215661	[3]	[2,4]	9	hSpCas9	positive selection	4355425
64496396	64496418	17	+	27760321	OCIAML3	viability	GTGAAGCATACCGTGAAGAAGG	POLG2	ENSG00000256525	-1.2311139009147425	[211,158]	[72,45]	-8	hSpCas9	negative selection	4429180
64496540	64496562	17	+	27760321	OCIAML3	viability	ACTGTCCCCGGGTAGCAAAGGG	POLG2	ENSG00000256525	-0.21779219766893387	[282,236]	[161,189]	-2	hSpCas9	negative selection	4429181
64496647	64496669	17	+	27760321	OCIAML3	viability	TCCGCAACTCTACGCCCAAGGG	POLG2	ENSG00000256525	-0.7024772329176245	[675,534]	[375,175]	-6	hSpCas9	negative selection	4429182
64496824	64496846	17	-	27760321	OCIAML3	viability	GGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.5848793638408254	[675,549]	[307,330]	-5	hSpCas9	negative selection	4429183
64496847	64496869	17	-	27760321	OCIAML3	viability	CGGAAAGGAGTAGCCCCAAAGG	POLG2	ENSG00000256525	-1.1604781930369754	[345,291]	[128,87]	-8	hSpCas9	negative selection	4429184
64496396	64496418	17	+	27760321	OCIAML2	viability	GTGAAGCATACCGTGAAGAAGG	POLG2	ENSG00000256525	-0.683447132495038	[211,158]	[80,107]	-6	hSpCas9	negative selection	4512643
64496540	64496562	17	+	27760321	OCIAML2	viability	ACTGTCCCCGGGTAGCAAAGGG	POLG2	ENSG00000256525	-0.4552548225533751	[282,236]	[160,141]	-5	hSpCas9	negative selection	4512644
64496647	64496669	17	+	27760321	OCIAML2	viability	TCCGCAACTCTACGCCCAAGGG	POLG2	ENSG00000256525	-0.7558567650984667	[675,534]	[188,418]	-7	hSpCas9	negative selection	4512645
64496824	64496846	17	-	27760321	OCIAML2	viability	GGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-1.3105939055569142	[675,549]	[172,232]	-8	hSpCas9	negative selection	4512646
64496847	64496869	17	-	27760321	OCIAML2	viability	CGGAAAGGAGTAGCCCCAAAGG	POLG2	ENSG00000256525	-1.456074600909969	[345,291]	[72,120]	-8	hSpCas9	negative selection	4512647
64496396	64496418	17	+	27760321	MV411	viability	GTGAAGCATACCGTGAAGAAGG	POLG2	ENSG00000256525	-2.168565996166564	[211,158]	[24,29]	-8	hSpCas9	negative selection	4596106
64496540	64496562	17	+	27760321	MV411	viability	ACTGTCCCCGGGTAGCAAAGGG	POLG2	ENSG00000256525	0.9879267332126755	[282,236]	[501,93]	7	hSpCas9	negative selection	4596107
64496647	64496669	17	+	27760321	MV411	viability	TCCGCAACTCTACGCCCAAGGG	POLG2	ENSG00000256525	0.15196290927748868	[675,534]	[644,134]	1	hSpCas9	negative selection	4596108
64496824	64496846	17	-	27760321	MV411	viability	GGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.19904471550088254	[675,549]	[316,400]	-1	hSpCas9	negative selection	4596109
64496847	64496869	17	-	27760321	MV411	viability	CGGAAAGGAGTAGCCCCAAAGG	POLG2	ENSG00000256525	-2.2794016829675643	[345,291]	[45,38]	-8	hSpCas9	negative selection	4596110
64496396	64496418	17	+	27760321	HL60	viability	GTGAAGCATACCGTGAAGAAGG	POLG2	ENSG00000256525	-1.4600080509332893	[211,158]	[74,32]	-8	hSpCas9	negative selection	4679569
64496540	64496562	17	+	27760321	HL60	viability	ACTGTCCCCGGGTAGCAAAGGG	POLG2	ENSG00000256525	-0.5584521661726348	[282,236]	[164,120]	-6	hSpCas9	negative selection	4679570
64496647	64496669	17	+	27760321	HL60	viability	TCCGCAACTCTACGCCCAAGGG	POLG2	ENSG00000256525	-0.6328515501056916	[675,534]	[249,387]	-6	hSpCas9	negative selection	4679571
64496824	64496846	17	-	27760321	HL60	viability	GGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.5331125823944171	[675,549]	[352,334]	-5	hSpCas9	negative selection	4679572
64496847	64496869	17	-	27760321	HL60	viability	CGGAAAGGAGTAGCCCCAAAGG	POLG2	ENSG00000256525	-1.3774791457359472	[345,291]	[80,119]	-8	hSpCas9	negative selection	4679573
64496396	64496418	17	+	27760321	HT1080	viability	GTGAAGCATACCGTGAAGAAGG	POLG2	ENSG00000256525	-3.1727164895000186	[158,123]	[0,11]	-7	hSpCas9	negative selection	4763032
64496540	64496562	17	+	27760321	HT1080	viability	ACTGTCCCCGGGTAGCAAAGGG	POLG2	ENSG00000256525	-3.2826610550200455	[236,184]	[0,16]	-7	hSpCas9	negative selection	4763033
64496647	64496669	17	+	27760321	HT1080	viability	TCCGCAACTCTACGCCCAAGGG	POLG2	ENSG00000256525	-0.9591436197637963	[534,417]	[184,1]	-4	hSpCas9	negative selection	4763034
64496824	64496846	17	-	27760321	HT1080	viability	GGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-1.6295363572451032	[549,428]	[73,50]	-5	hSpCas9	negative selection	4763035
64496847	64496869	17	-	27760321	HT1080	viability	CGGAAAGGAGTAGCCCCAAAGG	POLG2	ENSG00000256525	-6.088009210779489	[291,227]	[1,0]	-9	hSpCas9	negative selection	4763036
64496396	64496418	17	+	27760321	HT29	viability after 7 days	GTGAAGCATACCGTGAAGAAGG	POLG2	ENSG00000256525	0.3403195832992789	[158,123]	[441,181,100]	5	hSpCas9	negative selection	4846495
64496540	64496562	17	+	27760321	HT29	viability after 7 days	ACTGTCCCCGGGTAGCAAAGGG	POLG2	ENSG00000256525	0.4231615803940724	[236,184]	[481,305,320]	6	hSpCas9	negative selection	4846496
64496647	64496669	17	+	27760321	HT29	viability after 7 days	TCCGCAACTCTACGCCCAAGGG	POLG2	ENSG00000256525	0.5466160549535327	[534,417]	[991,927,780]	8	hSpCas9	negative selection	4846497
64496824	64496846	17	-	27760321	HT29	viability after 7 days	GGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	0.3249352991130846	[549,428]	[570,534,1212]	5	hSpCas9	negative selection	4846498
64496847	64496869	17	-	27760321	HT29	viability after 7 days	CGGAAAGGAGTAGCCCCAAAGG	POLG2	ENSG00000256525	0.28911233102085854	[291,227]	[330,258,616]	4	hSpCas9	negative selection	4846499
64496396	64496418	17	+	27760321	HT29	viability after 25 days	GTGAAGCATACCGTGAAGAAGG	POLG2	ENSG00000256525	-2.031319191928641	[158,123]	[41,14,63]	-8	hSpCas9	negative selection	4929958
64496540	64496562	17	+	27760321	HT29	viability after 25 days	ACTGTCCCCGGGTAGCAAAGGG	POLG2	ENSG00000256525	-0.8462800046908816	[236,184]	[196,111,83]	-6	hSpCas9	negative selection	4929959
64496647	64496669	17	+	27760321	HT29	viability after 25 days	TCCGCAACTCTACGCCCAAGGG	POLG2	ENSG00000256525	-2.980362716495466	[534,417]	[47,144,8]	-8	hSpCas9	negative selection	4929960
64496824	64496846	17	-	27760321	HT29	viability after 25 days	GGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.6787269303482852	[549,428]	[339,224,498]	-5	hSpCas9	negative selection	4929961
64496847	64496869	17	-	27760321	HT29	viability after 25 days	CGGAAAGGAGTAGCCCCAAAGG	POLG2	ENSG00000256525	-1.9326422767190232	[291,227]	[15,188,26]	-8	hSpCas9	negative selection	4929962
64496396	64496418	17	+	27760321	HT29	viability after 22 days	GTGAAGCATACCGTGAAGAAGG	POLG2	ENSG00000256525	-0.8555584520152966	[158,123]	[199,1,65]	-6	hSpCas9	negative selection	5013421
64496540	64496562	17	+	27760321	HT29	viability after 22 days	ACTGTCCCCGGGTAGCAAAGGG	POLG2	ENSG00000256525	-0.7992440614870413	[236,184]	[87,185,147]	-6	hSpCas9	negative selection	5013422
64496647	64496669	17	+	27760321	HT29	viability after 22 days	TCCGCAACTCTACGCCCAAGGG	POLG2	ENSG00000256525	-2.074136834006933	[534,417]	[135,159,95]	-8	hSpCas9	negative selection	5013423
64496824	64496846	17	-	27760321	HT29	viability after 22 days	GGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.6863316009668395	[549,428]	[263,367,425]	-5	hSpCas9	negative selection	5013424
64496847	64496869	17	-	27760321	HT29	viability after 22 days	CGGAAAGGAGTAGCCCCAAAGG	POLG2	ENSG00000256525	-1.2977309338822862	[291,227]	[49,169,148]	-7	hSpCas9	negative selection	5013425
64496396	64496418	17	+	27760321	HT29	viability after 19 days	GTGAAGCATACCGTGAAGAAGG	POLG2	ENSG00000256525	-1.3109371495448943	[158,123]	[191,7,10]	-7	hSpCas9	negative selection	5096884
64496540	64496562	17	+	27760321	HT29	viability after 19 days	ACTGTCCCCGGGTAGCAAAGGG	POLG2	ENSG00000256525	-1.3001194376476495	[236,184]	[114,36,141]	-7	hSpCas9	negative selection	5096885
64496647	64496669	17	+	27760321	HT29	viability after 19 days	TCCGCAACTCTACGCCCAAGGG	POLG2	ENSG00000256525	-0.12639427775669898	[534,417]	[444,444,597]	-1	hSpCas9	negative selection	5096886
64496824	64496846	17	-	27760321	HT29	viability after 19 days	GGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.33054279586688795	[549,428]	[336,275,700]	-3	hSpCas9	negative selection	5096887
64496847	64496869	17	-	27760321	HT29	viability after 19 days	CGGAAAGGAGTAGCCCCAAAGG	POLG2	ENSG00000256525	-1.1574924474512964	[291,227]	[279,130,8]	-7	hSpCas9	negative selection	5096888
64496396	64496418	17	+	27760321	HT29	viability after 16 days	GTGAAGCATACCGTGAAGAAGG	POLG2	ENSG00000256525	-0.7885299089958191	[158,123]	[161,36,83]	-6	hSpCas9	negative selection	5180347
64496540	64496562	17	+	27760321	HT29	viability after 16 days	ACTGTCCCCGGGTAGCAAAGGG	POLG2	ENSG00000256525	0.55140763150595	[236,184]	[297,395,337]	6	hSpCas9	negative selection	5180348
64496647	64496669	17	+	27760321	HT29	viability after 16 days	TCCGCAACTCTACGCCCAAGGG	POLG2	ENSG00000256525	-0.10980685195087025	[534,417]	[539,588,354]	-1	hSpCas9	negative selection	5180349
64496824	64496846	17	-	27760321	HT29	viability after 16 days	GGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	0.08917965525086569	[549,428]	[355,588,780]	0	hSpCas9	negative selection	5180350
64496847	64496869	17	-	27760321	HT29	viability after 16 days	CGGAAAGGAGTAGCCCCAAAGG	POLG2	ENSG00000256525	-0.28359678984602243	[291,227]	[225,226,262]	-3	hSpCas9	negative selection	5180351
64496396	64496418	17	+	27760321	HT29	viability after 13 days	GTGAAGCATACCGTGAAGAAGG	POLG2	ENSG00000256525	-0.48669046320393394	[158,123]	[191,20,136]	-5	hSpCas9	negative selection	5263810
64496540	64496562	17	+	27760321	HT29	viability after 13 days	ACTGTCCCCGGGTAGCAAAGGG	POLG2	ENSG00000256525	0.15399152182337905	[236,184]	[210,347,258]	1	hSpCas9	negative selection	5263811
64496647	64496669	17	+	27760321	HT29	viability after 13 days	TCCGCAACTCTACGCCCAAGGG	POLG2	ENSG00000256525	0.18789904070280605	[534,417]	[623,616,646]	2	hSpCas9	negative selection	5263812
64496824	64496846	17	-	27760321	HT29	viability after 13 days	GGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	0.2528575250101681	[549,428]	[621,698,706]	3	hSpCas9	negative selection	5263813
64496847	64496869	17	-	27760321	HT29	viability after 13 days	CGGAAAGGAGTAGCCCCAAAGG	POLG2	ENSG00000256525	-0.05752197804299375	[291,227]	[170,429,269]	0	hSpCas9	negative selection	5263814
64496396	64496418	17	+	27760321	HT29	viability after 10 days	GTGAAGCATACCGTGAAGAAGG	POLG2	ENSG00000256525	0.26420823948697914	[158,123]	[195,189,248]	3	hSpCas9	negative selection	5347273
64496540	64496562	17	+	27760321	HT29	viability after 10 days	ACTGTCCCCGGGTAGCAAAGGG	POLG2	ENSG00000256525	0.3392581760531737	[236,184]	[428,193,371]	4	hSpCas9	negative selection	5347274
64496647	64496669	17	+	27760321	HT29	viability after 10 days	TCCGCAACTCTACGCCCAAGGG	POLG2	ENSG00000256525	0.29130039797908824	[534,417]	[762,708,711]	4	hSpCas9	negative selection	5347275
64496824	64496846	17	-	27760321	HT29	viability after 10 days	GGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	0.5477185493656274	[549,428]	[729,927,1019]	7	hSpCas9	negative selection	5347276
64496847	64496869	17	-	27760321	HT29	viability after 10 days	CGGAAAGGAGTAGCCCCAAAGG	POLG2	ENSG00000256525	0.5391389132810386	[291,227]	[550,333,524]	7	hSpCas9	negative selection	5347277
64496396	64496418	17	+	27760321	MOLM13	viability	GTGAAGCATACCGTGAAGAAGG	POLG2	ENSG00000256525	-0.4306720301106317	[211,158]	[103,53]	-3	hSpCas9	negative selection	5430736
64496540	64496562	17	+	27760321	MOLM13	viability	ACTGTCCCCGGGTAGCAAAGGG	POLG2	ENSG00000256525	-0.13092470829352687	[282,236]	[93,166]	-1	hSpCas9	negative selection	5430737
64496647	64496669	17	+	27760321	MOLM13	viability	TCCGCAACTCTACGCCCAAGGG	POLG2	ENSG00000256525	-0.5632284263675257	[675,534]	[185,266]	-4	hSpCas9	negative selection	5430738
64496824	64496846	17	-	27760321	MOLM13	viability	GGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.3270861561834937	[675,549]	[431,139]	-2	hSpCas9	negative selection	5430739
64496847	64496869	17	-	27760321	MOLM13	viability	CGGAAAGGAGTAGCCCCAAAGG	POLG2	ENSG00000256525	-1.0686309480434204	[345,291]	[172,10]	-6	hSpCas9	negative selection	5430740
64496997	64497020	17	-	27661255	K562	viability	GTTGGGATCCGTTGAGTGATGGG	POLG2	ENSG00000256525	-1.6786880654998453	[2708,3039]	[752,683]	-9	dCas9-KRAB	negative selection	5503025
64497023	64497046	17	-	27661255	K562	viability	GATTCTGTTAACGGTAGTGGTGG	POLG2	ENSG00000256525	-2.422732442006823	[1217,1367]	[249,142]	-9	dCas9-KRAB	negative selection	5503026
64497032	64497055	17	-	27661255	K562	viability	GCCTCTCCGGATTCTGTTAACGG	POLG2	ENSG00000256525	-1.9660642853428263	[1080,1170]	[217,239]	-9	dCas9-KRAB	negative selection	5503027
64492676	64492699	17	-	27260156	BXPC3	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.2741057159189415	[55]	[37,48,47,60]	-6	hSpCas9	negative selection	5563634
64492739	64492762	17	-	27260156	BXPC3	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.17854730504680716	[197]	[146,139,230,224]	-4	hSpCas9	negative selection	5563635
64485796	64485819	17	-	27260156	BXPC3	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	0.10957385154956895	[389]	[432,435,405,487]	2	hSpCas9	negative selection	5563636
64492904	64492927	17	-	27260156	BXPC3	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-1.1159550400985387	[78]	[8,31,47,70]	-9	hSpCas9	negative selection	5627883
64485844	64485867	17	-	27260156	BXPC3	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.14100021973971089	[124]	[61,82,140,206]	-3	hSpCas9	negative selection	5627884
64490828	64490851	17	+	27260156	BXPC3	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.5195495061492006	[538]	[295,340,452,508]	-8	hSpCas9	negative selection	5627885
64492676	64492699	17	-	27260156	A673	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	0.21861057372395587	[55]	[69,90,109,37]	5	hSpCas9	negative selection	5684885
64492739	64492762	17	-	27260156	A673	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.11550219318825317	[197]	[318,198,237,283]	2	hSpCas9	negative selection	5684886
64485796	64485819	17	-	27260156	A673	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.08282145353103909	[389]	[518,428,393,434]	-2	hSpCas9	negative selection	5684887
64492904	64492927	17	-	27260156	A673	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.8077672923462145	[78]	[98,50,35,34]	-9	hSpCas9	negative selection	5749134
64485844	64485867	17	-	27260156	A673	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.09453552686349576	[124]	[158,69,180,236]	2	hSpCas9	negative selection	5749135
64490828	64490851	17	+	27260156	A673	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.40732872388600794	[538]	[517,396,556,483]	-7	hSpCas9	negative selection	5749136
64492676	64492699	17	-	27260156	A375	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.5715843756254637	[55]	[27,10,48,0]	-9	hSpCas9	negative selection	5806136
64492739	64492762	17	-	27260156	A375	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.9288345109519829	[197]	[60,241,134,69]	-8	hSpCas9	negative selection	5806137
64485796	64485819	17	-	27260156	A375	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.2849968292301264	[389]	[449,378,326,342]	-4	hSpCas9	negative selection	5806138
64492904	64492927	17	-	27260156	A375	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.41586741723203735	[78]	[77,46,121,30]	-5	hSpCas9	negative selection	5870385
64485844	64485867	17	-	27260156	A375	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.029380721524468578	[124]	[124,283,157,36]	0	hSpCas9	negative selection	5870386
64490828	64490851	17	+	27260156	A375	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.5794605731387783	[538]	[373,341,643,323]	-7	hSpCas9	negative selection	5870387
64492676	64492699	17	-	27260156	COLO741	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.648378365492436	[55]	[31,61,41]	-8	hSpCas9	negative selection	5927387
64492739	64492762	17	-	27260156	COLO741	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.36613016360470074	[197]	[478,238,275]	7	hSpCas9	negative selection	5927388
64485796	64485819	17	-	27260156	COLO741	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.4558095893462217	[389]	[395,306,386]	-7	hSpCas9	negative selection	5927389
64492904	64492927	17	-	27260156	COLO741	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.9180081229941979	[78]	[93,36,33]	-9	hSpCas9	negative selection	5991636
64485844	64485867	17	-	27260156	COLO741	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.12111771809546745	[124]	[184,147,112]	-3	hSpCas9	negative selection	5991637
64490828	64490851	17	+	27260156	COLO741	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.3121126470890485	[538]	[475,522,649]	-6	hSpCas9	negative selection	5991638
64492676	64492699	17	-	27260156	CAL120	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.1942311280559377	[55]	[11,69,6]	-9	hSpCas9	negative selection	6048638
64492739	64492762	17	-	27260156	CAL120	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.5160910231159499	[197]	[352,294,407]	7	hSpCas9	negative selection	6048639
64485796	64485819	17	-	27260156	CAL120	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.018560744071799085	[389]	[572,496,382]	0	hSpCas9	negative selection	6048640
64492904	64492927	17	-	27260156	CAL120	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.22601331755101617	[78]	[68,48,130]	-3	hSpCas9	negative selection	6112887
64485844	64485867	17	-	27260156	CAL120	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.6659508985890947	[124]	[58,119,108]	-7	hSpCas9	negative selection	6112888
64490828	64490851	17	+	27260156	CAL120	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.1651369123782947	[538]	[836,549,445]	-2	hSpCas9	negative selection	6112889
64492676	64492699	17	-	27260156	CADOES1	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.11344033936945008	[55]	[50,47,59,32]	-2	hSpCas9	negative selection	6169889
64492739	64492762	17	-	27260156	CADOES1	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.08356656342251734	[197]	[231,166,195,184]	1	hSpCas9	negative selection	6169890
64485796	64485819	17	-	27260156	CADOES1	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.2933243268410303	[389]	[309,312,263,296]	-5	hSpCas9	negative selection	6169891
64492904	64492927	17	-	27260156	CADOES1	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.7211365565150225	[78]	[40,32,40,63]	-8	hSpCas9	negative selection	6234138
64485844	64485867	17	-	27260156	CADOES1	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.0521439206641543	[124]	[174,79,78,148]	0	hSpCas9	negative selection	6234139
64490828	64490851	17	+	27260156	CADOES1	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.4445098858370199	[538]	[454,320,307,389]	-7	hSpCas9	negative selection	6234140
64492676	64492699	17	-	27260156	EWS502	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.0619673300969925	[55]	[27,29,18,36]	-9	hSpCas9	negative selection	6291140
64492739	64492762	17	-	27260156	EWS502	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.23602108778135178	[197]	[316,145,304,212]	4	hSpCas9	negative selection	6291141
64485796	64485819	17	-	27260156	EWS502	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.36524693952137494	[389]	[318,284,305,376]	-6	hSpCas9	negative selection	6291142
64492904	64492927	17	-	27260156	EWS502	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-1.1379941365431683	[78]	[41,9,61,38]	-9	hSpCas9	negative selection	6355389
64485844	64485867	17	-	27260156	EWS502	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.4170599100045278	[124]	[150,73,259,233]	7	hSpCas9	negative selection	6355390
64490828	64490851	17	+	27260156	EWS502	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.41829805202321024	[538]	[314,322,394,711]	-6	hSpCas9	negative selection	6355391
64492676	64492699	17	-	27260156	EW8	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	0.0876226888683278	[55]	[81,33,26,56]	1	hSpCas9	negative selection	6412391
64492739	64492762	17	-	27260156	EW8	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.2635122978086698	[197]	[179,137,246,193]	5	hSpCas9	negative selection	6412392
64485796	64485819	17	-	27260156	EW8	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.4725692465260252	[389]	[250,222,197,245]	-7	hSpCas9	negative selection	6412393
64492904	64492927	17	-	27260156	EW8	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.12469665313203482	[78]	[28,82,67,49]	-2	hSpCas9	negative selection	6476640
64485844	64485867	17	-	27260156	EW8	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.2254651843538742	[124]	[111,42,148,162]	4	hSpCas9	negative selection	6476641
64490828	64490851	17	+	27260156	EW8	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.8509704106414737	[538]	[221,253,198,297]	-9	hSpCas9	negative selection	6476642
64492676	64492699	17	-	27260156	CORL105	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	0.05210199004525595	[55]	[39,89,108,37]	1	hSpCas9	negative selection	6533642
64492739	64492762	17	-	27260156	CORL105	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.21849690124553756	[197]	[180,125,178,307]	-4	hSpCas9	negative selection	6533643
64485796	64485819	17	-	27260156	CORL105	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	0.06007479821945705	[389]	[472,534,483,411]	1	hSpCas9	negative selection	6533644
64492904	64492927	17	-	27260156	CORL105	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-1.5317279826557573	[78]	[9,24,11,76]	-9	hSpCas9	negative selection	6597891
64485844	64485867	17	-	27260156	CORL105	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.274739856393202	[124]	[268,176,191,75]	5	hSpCas9	negative selection	6597892
64490828	64490851	17	+	27260156	CORL105	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.5873249670272311	[538]	[671,244,443,334]	-8	hSpCas9	negative selection	6597893
64492676	64492699	17	-	27260156	HS294T	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.0751320957648636	[55]	[9,6,14,8]	-9	hSpCas9	negative selection	6654893
64492739	64492762	17	-	27260156	HS294T	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.3758922764818038	[197]	[45,21,52,128]	-5	hSpCas9	negative selection	6654894
64485796	64485819	17	-	27260156	HS294T	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.3482973140727637	[389]	[108,115,122,127]	-5	hSpCas9	negative selection	6654895
64492904	64492927	17	-	27260156	HS294T	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-1.9269428250799145	[78]	[4,4,11,10]	-9	hSpCas9	negative selection	6719142
64485844	64485867	17	-	27260156	HS294T	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.2388943370233534	[124]	[21,46,41,56]	-3	hSpCas9	negative selection	6719143
64490828	64490851	17	+	27260156	HS294T	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.6564799701134612	[538]	[117,173,95,141]	-7	hSpCas9	negative selection	6719144
64492676	64492699	17	-	27260156	HCC44	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.4643752831606549	[55]	[21,58,40,55]	-6	hSpCas9	negative selection	6776144
64492739	64492762	17	-	27260156	HCC44	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.24590743954069594	[197]	[261,245,281,274]	4	hSpCas9	negative selection	6776145
64485796	64485819	17	-	27260156	HCC44	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.11465297644846917	[389]	[428,370,528,327]	-2	hSpCas9	negative selection	6776146
64492904	64492927	17	-	27260156	HCC44	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.5480231356515484	[78]	[112,26,71,43]	-7	hSpCas9	negative selection	6840393
64485844	64485867	17	-	27260156	HCC44	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.395793784416385	[124]	[143,41,110,143]	-6	hSpCas9	negative selection	6840394
64490828	64490851	17	+	27260156	HCC44	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.39833933607284144	[538]	[546,404,438,466]	-6	hSpCas9	negative selection	6840395
64492676	64492699	17	-	27260156	G402	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.23975708902499	[55]	[27,48,17,21]	-8	hSpCas9	negative selection	6897395
64492739	64492762	17	-	27260156	G402	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.9532243606800402	[197]	[601,561,406,329]	9	hSpCas9	negative selection	6897396
64485796	64485819	17	-	27260156	G402	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.16401382230099243	[389]	[506,293,420,476]	-2	hSpCas9	negative selection	6897397
64492904	64492927	17	-	27260156	G402	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.6806433260038629	[78]	[7,108,44,72]	-7	hSpCas9	negative selection	6961644
64485844	64485867	17	-	27260156	G402	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.024756651703452093	[124]	[210,224,61,115]	0	hSpCas9	negative selection	6961645
64490828	64490851	17	+	27260156	G402	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.17685252845190214	[538]	[726,338,305,941]	-2	hSpCas9	negative selection	6961646
64492676	64492699	17	-	27260156	L33	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.7756567680282735	[55]	[22,13,19,41]	-9	hSpCas9	negative selection	7018646
64492739	64492762	17	-	27260156	L33	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.3302093869539541	[197]	[342,101,120,208]	7	hSpCas9	negative selection	7018647
64485796	64485819	17	-	27260156	L33	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	0.09553652343814434	[389]	[504,202,252,262]	2	hSpCas9	negative selection	7018648
64492904	64492927	17	-	27260156	L33	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.4330490496288615	[78]	[47,15,45,73]	-8	hSpCas9	negative selection	7082895
64485844	64485867	17	-	27260156	L33	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.24697269487352247	[124]	[176,65,99,95]	5	hSpCas9	negative selection	7082896
64490828	64490851	17	+	27260156	L33	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.19471397526444834	[538]	[509,166,281,515]	-4	hSpCas9	negative selection	7082897
64492676	64492699	17	-	27260156	K562	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.1463645547626866	[55]	[42,14,19,13]	-8	hSpCas9	negative selection	7139897
64492739	64492762	17	-	27260156	K562	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.4780060471532983	[197]	[370,350,160,124]	6	hSpCas9	negative selection	7139898
64485796	64485819	17	-	27260156	K562	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.09342692323761609	[389]	[230,198,244,576]	-1	hSpCas9	negative selection	7139899
64492904	64492927	17	-	27260156	K562	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-1.7277506178453117	[78]	[29,7,47,0]	-9	hSpCas9	negative selection	7204146
64485844	64485867	17	-	27260156	K562	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.5481780166290096	[124]	[155,235,186,81]	7	hSpCas9	negative selection	7204147
64490828	64490851	17	+	27260156	K562	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.13742444390383665	[538]	[472,205,230,777]	-2	hSpCas9	negative selection	7204148
64492676	64492699	17	-	27260156	HT29	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.2542238455416057	[55]	[45,41,73,62]	-5	hSpCas9	negative selection	7261148
64492739	64492762	17	-	27260156	HT29	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.3080541500202656	[197]	[148,242,271,121]	-5	hSpCas9	negative selection	7261149
64485796	64485819	17	-	27260156	HT29	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.13187798232024128	[389]	[352,538,427,412]	-3	hSpCas9	negative selection	7261150
64492904	64492927	17	-	27260156	HT29	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.7459862991013111	[78]	[80,55,41,51]	-8	hSpCas9	negative selection	7325397
64485844	64485867	17	-	27260156	HT29	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.2636419206949303	[124]	[107,99,205,91]	-5	hSpCas9	negative selection	7325398
64490828	64490851	17	+	27260156	HT29	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.2933827782626055	[538]	[513,379,611,604]	-5	hSpCas9	negative selection	7325399
64492676	64492699	17	-	27260156	MHHES1	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.6422637200336005	[55]	[96,7,2,52]	-8	hSpCas9	negative selection	7382399
64492739	64492762	17	-	27260156	MHHES1	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.22331253024523212	[197]	[168,218,171,197]	-4	hSpCas9	negative selection	7382400
64485796	64485819	17	-	27260156	MHHES1	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	0.010017101387754246	[389]	[501,343,415,483]	0	hSpCas9	negative selection	7382401
64492904	64492927	17	-	27260156	MHHES1	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.854297392997875	[78]	[24,34,33,87]	-9	hSpCas9	negative selection	7446648
64485844	64485867	17	-	27260156	MHHES1	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.03382246495927044	[124]	[105,187,85,161]	0	hSpCas9	negative selection	7446649
64490828	64490851	17	+	27260156	MHHES1	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.27398088028432144	[538]	[490,551,596,387]	-5	hSpCas9	negative selection	7446650
64492676	64492699	17	-	27260156	MEWO	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.4813452212319165	[55]	[39,48,23]	-8	hSpCas9	negative selection	7503650
64492739	64492762	17	-	27260156	MEWO	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.9190001664618517	[197]	[377,362,314]	9	hSpCas9	negative selection	7503651
64485796	64485819	17	-	27260156	MEWO	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.5143049186235538	[389]	[300,282,190]	-8	hSpCas9	negative selection	7503652
64492904	64492927	17	-	27260156	MEWO	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-1.190222874191249	[78]	[56,17,26]	-9	hSpCas9	negative selection	7567899
64485844	64485867	17	-	27260156	MEWO	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.04398609071930992	[124]	[146,67,131]	-1	hSpCas9	negative selection	7567900
64490828	64490851	17	+	27260156	MEWO	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.37801064265941753	[538]	[508,274,403]	-7	hSpCas9	negative selection	7567901
64492676	64492699	17	-	27260156	LNCAPCLONEFGC	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.9356394622017508	[55]	[10,78,6,2]	-8	hSpCas9	negative selection	7624901
64492739	64492762	17	-	27260156	LNCAPCLONEFGC	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.07781262783171816	[197]	[189,157,236,104]	-1	hSpCas9	negative selection	7624902
64485796	64485819	17	-	27260156	LNCAPCLONEFGC	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.004691643850461669	[389]	[413,355,305,323]	0	hSpCas9	negative selection	7624903
64492904	64492927	17	-	27260156	LNCAPCLONEFGC	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.479024521247049	[78]	[37,71,69,26]	-6	hSpCas9	negative selection	7689150
64485844	64485867	17	-	27260156	LNCAPCLONEFGC	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.0417684296418237	[124]	[62,143,113,143]	0	hSpCas9	negative selection	7689151
64490828	64490851	17	+	27260156	LNCAPCLONEFGC	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.3663565350499885	[538]	[363,334,560,284]	-5	hSpCas9	negative selection	7689152
64492676	64492699	17	-	27260156	PANC0327	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.4185603018288777	[55]	[28,12,14,18]	-9	hSpCas9	negative selection	7746152
64492739	64492762	17	-	27260156	PANC0327	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.30576566791346593	[197]	[179,141,153,399]	4	hSpCas9	negative selection	7746153
64485796	64485819	17	-	27260156	PANC0327	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	0.08836307241345276	[389]	[327,480,204,440]	1	hSpCas9	negative selection	7746154
64492904	64492927	17	-	27260156	PANC0327	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	1.2482369476483224	[78]	[64,73,54,475]	9	hSpCas9	negative selection	7810401
64485844	64485867	17	-	27260156	PANC0327	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.186896240893764	[124]	[56,95,94,138]	-3	hSpCas9	negative selection	7810402
64490828	64490851	17	+	27260156	PANC0327	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.5141316340637008	[538]	[434,335,297,279]	-6	hSpCas9	negative selection	7810403
64492676	64492699	17	-	27260156	NCIH2009	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.1973115600635111	[55]	[36,26,38]	-8	hSpCas9	negative selection	7867403
64492739	64492762	17	-	27260156	NCIH2009	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-1.6126527169508897	[197]	[103,84,84]	-9	hSpCas9	negative selection	7867404
64485796	64485819	17	-	27260156	NCIH2009	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	0.14818337831434752	[389]	[848,434,577]	2	hSpCas9	negative selection	7867405
64492904	64492927	17	-	27260156	NCIH2009	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-3.322059084029617	[78]	[15,14,2]	-9	hSpCas9	negative selection	7931652
64485844	64485867	17	-	27260156	NCIH2009	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.7367035162154938	[124]	[105,130,76]	-7	hSpCas9	negative selection	7931653
64490828	64490851	17	+	27260156	NCIH2009	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-1.0020050610503746	[538]	[373,485,264]	-8	hSpCas9	negative selection	7931654
64492676	64492699	17	-	27260156	NCIH1373	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.1998794974662577	[55]	[41,9,9,13]	-8	hSpCas9	negative selection	7988654
64492739	64492762	17	-	27260156	NCIH1373	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.7907021715253124	[197]	[65,85,104,67]	-7	hSpCas9	negative selection	7988655
64485796	64485819	17	-	27260156	NCIH1373	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	0.4282973744632237	[389]	[372,972,472,117]	4	hSpCas9	negative selection	7988656
64492904	64492927	17	-	27260156	NCIH1373	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-2.3350090283754423	[78]	[8,19,16,5]	-9	hSpCas9	negative selection	8052903
64485844	64485867	17	-	27260156	NCIH1373	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	1.0242285131236164	[124]	[87,507,395,19]	9	hSpCas9	negative selection	8052904
64490828	64490851	17	+	27260156	NCIH1373	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	0.134050778870771	[538]	[1094,357,798,126]	1	hSpCas9	negative selection	8052905
64492676	64492699	17	-	27260156	PATU8902	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.4308971818246139	[55]	[7,73,83,58]	-4	hSpCas9	negative selection	8109905
64492739	64492762	17	-	27260156	PATU8902	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.4988689060383624	[197]	[45,623,40,99]	-5	hSpCas9	negative selection	8109906
64485796	64485819	17	-	27260156	PATU8902	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.5877847820806241	[389]	[592,319,179,397]	-5	hSpCas9	negative selection	8109907
64492904	64492927	17	-	27260156	PATU8902	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.5262208366162469	[78]	[132,44,58,70]	-5	hSpCas9	negative selection	8174154
64485844	64485867	17	-	27260156	PATU8902	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.9675512958318885	[124]	[100,634,267,382]	9	hSpCas9	negative selection	8174155
64490828	64490851	17	+	27260156	PATU8902	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.7629560648542784	[538]	[477,496,195,687]	-6	hSpCas9	negative selection	8174156
64492676	64492699	17	-	27260156	PANC1	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.9272232022690781	[55]	[35,9,16,32]	-8	hSpCas9	negative selection	8231156
64492739	64492762	17	-	27260156	PANC1	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.1600780586184718	[197]	[188,234,120,87]	-3	hSpCas9	negative selection	8231157
64485796	64485819	17	-	27260156	PANC1	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.2525332790925859	[389]	[274,297,318,238]	-4	hSpCas9	negative selection	8231158
64492904	64492927	17	-	27260156	PANC1	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-1.1894298197572568	[78]	[16,48,8,44]	-9	hSpCas9	negative selection	8295405
64485844	64485867	17	-	27260156	PANC1	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.16210836186562183	[124]	[98,113,151,113]	2	hSpCas9	negative selection	8295406
64490828	64490851	17	+	27260156	PANC1	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.7372415048735623	[538]	[321,221,306,247]	-8	hSpCas9	negative selection	8295407
64492676	64492699	17	-	27260156	PANC0813	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.056923054537882	[55]	[11,60,27,23]	-8	hSpCas9	negative selection	8352407
64492739	64492762	17	-	27260156	PANC0813	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.4240014779262895	[197]	[214,101,237,143]	-6	hSpCas9	negative selection	8352408
64485796	64485819	17	-	27260156	PANC0813	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	0.11759462036834686	[389]	[703,434,441,428]	2	hSpCas9	negative selection	8352409
64492904	64492927	17	-	27260156	PANC0813	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-1.6254819501819324	[78]	[55,24,18,22]	-9	hSpCas9	negative selection	8416656
64485844	64485867	17	-	27260156	PANC0813	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.19610662675058577	[124]	[242,167,148,121]	3	hSpCas9	negative selection	8416657
64490828	64490851	17	+	27260156	PANC0813	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.5291964344439715	[538]	[531,336,404,485]	-7	hSpCas9	negative selection	8416658
64492676	64492699	17	-	27260156	RDES	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.13511309301312346	[55]	[55,71,38,64]	-2	hSpCas9	negative selection	8473658
64492739	64492762	17	-	27260156	RDES	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.5327294172010945	[197]	[314,343,279,373]	8	hSpCas9	negative selection	8473659
64485796	64485819	17	-	27260156	RDES	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	0.06460095376689828	[389]	[485,397,413,579]	1	hSpCas9	negative selection	8473660
64492904	64492927	17	-	27260156	RDES	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.2909772665533241	[78]	[53,36,78,143]	-5	hSpCas9	negative selection	8537907
64485844	64485867	17	-	27260156	RDES	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.19218074577972288	[124]	[94,164,99,143]	-3	hSpCas9	negative selection	8537908
64490828	64490851	17	+	27260156	RDES	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.1268375401424242	[538]	[555,500,588,623]	-2	hSpCas9	negative selection	8537909
64492676	64492699	17	-	27260156	PC3	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.193847607823078	[55]	[29,11,33,18]	-9	hSpCas9	negative selection	8594909
64492739	64492762	17	-	27260156	PC3	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.5528065144803255	[197]	[148,332,336,396]	9	hSpCas9	negative selection	8594910
64485796	64485819	17	-	27260156	PC3	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.1704730709980682	[389]	[211,375,536,354]	-4	hSpCas9	negative selection	8594911
64492904	64492927	17	-	27260156	PC3	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	0.057011528360135344	[78]	[53,38,219,74]	1	hSpCas9	negative selection	8659158
64485844	64485867	17	-	27260156	PC3	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.1852330495574872	[124]	[59,92,160,295]	4	hSpCas9	negative selection	8659159
64490828	64490851	17	+	27260156	PC3	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.16804479817632495	[538]	[304,520,648,531]	-4	hSpCas9	negative selection	8659160
64492676	64492699	17	-	27260156	PATU8988T	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.8347182890956968	[55]	[22,24,9,65]	-8	hSpCas9	negative selection	8716160
64492739	64492762	17	-	27260156	PATU8988T	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.1734722984511614	[197]	[86,115,237,236]	-3	hSpCas9	negative selection	8716161
64485796	64485819	17	-	27260156	PATU8988T	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.5038180526224294	[389]	[215,229,195,431]	-7	hSpCas9	negative selection	8716162
64492904	64492927	17	-	27260156	PATU8988T	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-1.2601747147276137	[78]	[10,24,23,69]	-9	hSpCas9	negative selection	8780409
64485844	64485867	17	-	27260156	PATU8988T	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.15432165888164318	[124]	[106,71,174,180]	2	hSpCas9	negative selection	8780410
64490828	64490851	17	+	27260156	PATU8988T	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.8713890253591763	[538]	[331,258,247,298]	-8	hSpCas9	negative selection	8780411
64492676	64492699	17	-	27260156	T47D	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.6908499597672075	[55]	[28,48,58,22]	-8	hSpCas9	negative selection	8837411
64492739	64492762	17	-	27260156	T47D	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.4711628082902819	[197]	[296,357,255,366]	8	hSpCas9	negative selection	8837412
64485796	64485819	17	-	27260156	T47D	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.1391167294044296	[389]	[454,376,398,422]	-3	hSpCas9	negative selection	8837413
64492904	64492927	17	-	27260156	T47D	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.7233339944498285	[78]	[65,53,32,70]	-8	hSpCas9	negative selection	8901660
64485844	64485867	17	-	27260156	T47D	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.26961632369150856	[124]	[155,215,128,198]	6	hSpCas9	negative selection	8901661
64490828	64490851	17	+	27260156	T47D	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.31089148851385295	[538]	[500,487,485,552]	-6	hSpCas9	negative selection	8901662
64492676	64492699	17	-	27260156	SU8686	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.36756260005036356	[55]	[31,29,48,67]	-6	hSpCas9	negative selection	8958662
64492739	64492762	17	-	27260156	SU8686	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	-0.015570426222035527	[197]	[190,186,197,201]	0	hSpCas9	negative selection	8958663
64485796	64485819	17	-	27260156	SU8686	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	0.1457700128709018	[389]	[478,474,338,394]	2	hSpCas9	negative selection	8958664
64492904	64492927	17	-	27260156	SU8686	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-1.134654938726273	[78]	[44,32,36,24]	-8	hSpCas9	negative selection	9022911
64485844	64485867	17	-	27260156	SU8686	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.19106550690112112	[124]	[67,74,191,109]	-3	hSpCas9	negative selection	9022912
64490828	64490851	17	+	27260156	SU8686	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.44163873934577214	[538]	[509,342,395,299]	-6	hSpCas9	negative selection	9022913
64492676	64492699	17	-	27260156	SKES1	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.26799953633839024	[55]	[61,53,31,40]	-5	hSpCas9	negative selection	9079913
64492739	64492762	17	-	27260156	SKES1	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.19708974732166884	[197]	[189,236,180,284]	4	hSpCas9	negative selection	9079914
64485796	64485819	17	-	27260156	SKES1	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.17590497370653924	[389]	[272,431,431,247]	-4	hSpCas9	negative selection	9079915
64492904	64492927	17	-	27260156	SKES1	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.4641629227324575	[78]	[72,36,53,62]	-8	hSpCas9	negative selection	9144162
64485844	64485867	17	-	27260156	SKES1	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.12986098085736053	[124]	[96,205,75,87]	-3	hSpCas9	negative selection	9144163
64490828	64490851	17	+	27260156	SKES1	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.42962415681769284	[538]	[324,475,426,366]	-7	hSpCas9	negative selection	9144164
64492676	64492699	17	-	27260156	TOV112D	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.6983521839576561	[55]	[21,43,21,50]	-8	hSpCas9	negative selection	9201164
64492739	64492762	17	-	27260156	TOV112D	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.7073955720686866	[197]	[409,334,137,418]	9	hSpCas9	negative selection	9201165
64485796	64485819	17	-	27260156	TOV112D	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.03743565509940561	[389]	[206,450,504,361]	0	hSpCas9	negative selection	9201166
64492904	64492927	17	-	27260156	TOV112D	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-1.821863067145792	[78]	[33,6,34,10]	-9	hSpCas9	negative selection	9265413
64485844	64485867	17	-	27260156	TOV112D	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	0.18276311604406548	[124]	[125,174,134,138]	3	hSpCas9	negative selection	9265414
64490828	64490851	17	+	27260156	TOV112D	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.404775910637456	[538]	[347,442,542,302]	-7	hSpCas9	negative selection	9265415
64492676	64492699	17	-	27260156	TC71	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	0.22526950382091337	[55]	[37,81,77,83]	5	hSpCas9	negative selection	9322415
64492739	64492762	17	-	27260156	TC71	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.45579034727858436	[197]	[270,275,242,381]	9	hSpCas9	negative selection	9322416
64485796	64485819	17	-	27260156	TC71	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	-0.09684127928506353	[389]	[524,377,345,307]	-2	hSpCas9	negative selection	9322417
64492904	64492927	17	-	27260156	TC71	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.6603977739351778	[78]	[15,76,44,78]	-9	hSpCas9	negative selection	9386664
64485844	64485867	17	-	27260156	TC71	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.10134635023652683	[124]	[99,133,156,106]	-3	hSpCas9	negative selection	9386665
64490828	64490851	17	+	27260156	TC71	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.5371492695433402	[538]	[309,348,464,472]	-9	hSpCas9	negative selection	9386666
64492676	64492699	17	-	27260156	TC32	viability	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	0.0718415764211282	[55]	[41,68,51,49]	1	hSpCas9	negative selection	9443666
64492739	64492762	17	-	27260156	TC32	viability	AGACTGAAGCTTCGTTAGTATGG	POLG2	ENSG00000256525	0.4092622155034551	[197]	[261,176,271,293]	7	hSpCas9	negative selection	9443667
64485796	64485819	17	-	27260156	TC32	viability	GGACCTAGACCGAGGCATGCTGG	POLG2	ENSG00000256525	0.03612959151955414	[389]	[362,250,439,493]	0	hSpCas9	negative selection	9443668
64492904	64492927	17	-	27260156	TC32	viability	GACACTAAGCAGATACGAAATGG	POLG2	ENSG00000256525	-0.19581747846247	[78]	[48,73,36,89]	-4	hSpCas9	negative selection	9507915
64485844	64485867	17	-	27260156	TC32	viability	CCGAGATGGACGAAAAAATGTGG	POLG2	ENSG00000256525	-0.1534837563254654	[124]	[102,67,98,162]	-3	hSpCas9	negative selection	9507916
64490828	64490851	17	+	27260156	TC32	viability	GTAAAAGTTCGTGATCTCCTAGG	POLG2	ENSG00000256525	-0.4530507952667553	[538]	[295,313,437,456]	-7	hSpCas9	negative selection	9507917
64485754	64485777	17	+	27869803	HPAFII	viability after 27 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	0.19788286067353655	[59]	[15,52,NaN]	1	hSpCas9	negative selection	9562380
64490951	64490974	17	+	27869803	HPAFII	viability after 27 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-1.0630072212869561	[499]	[55,183,NaN]	-6	hSpCas9	negative selection	9562381
64492676	64492699	17	-	27869803	HPAFII	viability after 27 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-6.320347059067882	[151]	[0,0,NaN]	-9	hSpCas9	negative selection	9562382
64492941	64492964	17	+	27869803	HPAFII	viability after 27 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-2.857091993189792	[217]	[23,8,NaN]	-9	hSpCas9	negative selection	9562383
64496620	64496643	17	+	27869803	HPAFII	viability after 27 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-6.232290882402686	[207]	[1,0,NaN]	-9	hSpCas9	negative selection	9562384
64496658	64496681	17	+	27869803	HPAFII	viability after 27 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.7991283757003147	[428]	[578,236,NaN]	6	hSpCas9	negative selection	9562385
64485754	64485777	17	+	27869803	HPAFII	viability after 15 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	0.49348038190214316	[59]	[83,94,NaN]	5	hSpCas9	negative selection	9644829
64490951	64490974	17	+	27869803	HPAFII	viability after 15 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-0.030611840892839637	[499]	[522,527,NaN]	0	hSpCas9	negative selection	9644830
64492676	64492699	17	-	27869803	HPAFII	viability after 15 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-1.568782077947294	[151]	[59,51,NaN]	-8	hSpCas9	negative selection	9644831
64492941	64492964	17	+	27869803	HPAFII	viability after 15 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.5003473376192683	[217]	[119,193,NaN]	-5	hSpCas9	negative selection	9644832
64496620	64496643	17	+	27869803	HPAFII	viability after 15 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-1.5771254812874487	[207]	[114,49,NaN]	-8	hSpCas9	negative selection	9644833
64496658	64496681	17	+	27869803	HPAFII	viability after 15 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.6425917605773339	[428]	[1143,455,NaN]	7	hSpCas9	negative selection	9644834
64485754	64485777	17	+	27869803	ASPC1	viability after 36 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	0.0016856327008976102	[177]	[59,50,71]	0	hSpCas9	negative selection	9727278
64490951	64490974	17	+	27869803	ASPC1	viability after 36 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-0.061819066703235115	[987]	[410,403,211]	0	hSpCas9	negative selection	9727279
64492676	64492699	17	-	27869803	ASPC1	viability after 36 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-0.6344720546474456	[312]	[89,39,79]	-6	hSpCas9	negative selection	9727280
64492941	64492964	17	+	27869803	ASPC1	viability after 36 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	1.0103555292711297	[491]	[95,303,550]	8	hSpCas9	negative selection	9727281
64496620	64496643	17	+	27869803	ASPC1	viability after 36 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	0.8494133501200467	[446]	[536,150,201]	7	hSpCas9	negative selection	9727282
64496658	64496681	17	+	27869803	ASPC1	viability after 36 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.1359438905419188	[1081]	[483,597,216]	1	hSpCas9	negative selection	9727283
64485754	64485777	17	+	27869803	PATU8988S	viability after 35 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	-0.23476484152805366	[148]	[49,51,NaN]	-2	hSpCas9	negative selection	9809727
64490951	64490974	17	+	27869803	PATU8988S	viability after 35 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-2.5682760261171573	[971]	[67,63,NaN]	-9	hSpCas9	negative selection	9809728
64492676	64492699	17	-	27869803	PATU8988S	viability after 35 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-3.679848022848441	[254]	[13,1,NaN]	-9	hSpCas9	negative selection	9809729
64492941	64492964	17	+	27869803	PATU8988S	viability after 35 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.5208483023145323	[385]	[42,173,NaN]	-5	hSpCas9	negative selection	9809730
64496620	64496643	17	+	27869803	PATU8988S	viability after 35 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-2.8148066558928297	[366]	[23,17,NaN]	-9	hSpCas9	negative selection	9809731
64496658	64496681	17	+	27869803	PATU8988S	viability after 35 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.8161206227448718	[1091]	[925,621,NaN]	8	hSpCas9	negative selection	9809732
64485754	64485777	17	+	27869803	PATU8988S	viability after 31 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	-0.20458188250693388	[148]	[40,64,NaN]	-2	hSpCas9	negative selection	9892176
64490951	64490974	17	+	27869803	PATU8988S	viability after 31 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-2.047450230142479	[971]	[91,95,NaN]	-9	hSpCas9	negative selection	9892177
64492676	64492699	17	-	27869803	PATU8988S	viability after 31 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-2.7303539511845223	[254]	[24,2,NaN]	-9	hSpCas9	negative selection	9892178
64492941	64492964	17	+	27869803	PATU8988S	viability after 31 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-0.43117843659242083	[385]	[74,163,NaN]	-5	hSpCas9	negative selection	9892179
64496620	64496643	17	+	27869803	PATU8988S	viability after 31 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-2.586694602909049	[366]	[26,20,NaN]	-9	hSpCas9	negative selection	9892180
64496658	64496681	17	+	27869803	PATU8988S	viability after 31 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.3527923286018084	[1091]	[625,466,NaN]	4	hSpCas9	negative selection	9892181
64485754	64485777	17	+	27869803	HPAFII	viability after 35 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	0.25883824199314653	[59]	[17,56,NaN]	1	hSpCas9	negative selection	9974625
64490951	64490974	17	+	27869803	HPAFII	viability after 35 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-2.123258917606754	[499]	[19,100,NaN]	-8	hSpCas9	negative selection	9974626
64492676	64492699	17	-	27869803	HPAFII	viability after 35 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-4.398645697495446	[151]	[5,0,NaN]	-9	hSpCas9	negative selection	9974627
64492941	64492964	17	+	27869803	HPAFII	viability after 35 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-2.1050865835880606	[217]	[35,13,NaN]	-8	hSpCas9	negative selection	9974628
64496620	64496643	17	+	27869803	HPAFII	viability after 35 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-6.718351165144417	[207]	[0,0,NaN]	-9	hSpCas9	negative selection	9974629
64496658	64496681	17	+	27869803	HPAFII	viability after 35 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.9825669926995722	[428]	[597,238,NaN]	6	hSpCas9	negative selection	9974630
64485754	64485777	17	+	27869803	HPAFII	viability after 31 days	TAAAGGAGTTCTCTGTCAGCTGG	POLG2	ENSG00000256525	0.036199344887355434	[59]	[23,45,NaN]	0	hSpCas9	negative selection	10057074
64490951	64490974	17	+	27869803	HPAFII	viability after 31 days	TAGATGGACTCATGGCAAACTGG	POLG2	ENSG00000256525	-1.336419843446941	[499]	[57,168,NaN]	-7	hSpCas9	negative selection	10057075
64492676	64492699	17	-	27869803	HPAFII	viability after 31 days	GGTTACGTCATCGACTCCAGTGG	POLG2	ENSG00000256525	-5.809129710487456	[151]	[1,0,NaN]	-9	hSpCas9	negative selection	10057076
64492941	64492964	17	+	27869803	HPAFII	viability after 31 days	AACACACTCCAATCTGAGCAAGG	POLG2	ENSG00000256525	-3.0570688751526665	[217]	[7,21,NaN]	-9	hSpCas9	negative selection	10057077
64496620	64496643	17	+	27869803	HPAFII	viability after 31 days	AGGTCCACCATTCTGCGGCCAGG	POLG2	ENSG00000256525	-6.867068518465834	[207]	[0,0,NaN]	-9	hSpCas9	negative selection	10057078
64496658	64496681	17	+	27869803	HPAFII	viability after 31 days	ACGCCCAAGGGTCCGAAGCCGGG	POLG2	ENSG00000256525	0.6230347959138804	[428]	[477,253,NaN]	4	hSpCas9	negative selection	10057079
64485804	64485827	17	-	28162770	P31FUJ	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-2.3736647402542284	[171]	[38]	-8	hSpCas9	negative selection	10214044
64492693	64492716	17	+	28162770	P31FUJ	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-6.529259611785623	[392]	[4]	-9	hSpCas9	negative selection	10214045
64496844	64496867	17	-	28162770	P31FUJ	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-1.4333351917870871	[130]	[56]	-7	hSpCas9	negative selection	10214046
64496824	64496847	17	-	28162770	P31FUJ	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-2.455194625750827	[125]	[26]	-8	hSpCas9	negative selection	10214047
64496662	64496685	17	+	28162770	P31FUJ	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-2.380700899526692	[194]	[43]	-8	hSpCas9	negative selection	10214048
64496611	64496634	17	-	28162770	P31FUJ	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-1.8957672171368078	[227]	[71]	-8	hSpCas9	negative selection	10214049
64496584	64496607	17	-	28162770	P31FUJ	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-5.186998514801253	[30]	[0]	-9	hSpCas9	negative selection	10214050
64496554	64496577	17	+	28162770	P31FUJ	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-0.34918138812870725	[399]	[368]	-3	hSpCas9	negative selection	10214051
64496538	64496561	17	+	28162770	P31FUJ	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-1.7346829636409797	[387]	[136]	-8	hSpCas9	negative selection	10214052
64492710	64492733	17	+	28162770	P31FUJ	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-3.791069838470115	[588]	[49]	-9	hSpCas9	negative selection	10214053
64485804	64485827	17	-	28162770	TF1	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10383410
64492693	64492716	17	+	28162770	TF1	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10383411
64496844	64496867	17	-	28162770	TF1	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10383412
64496824	64496847	17	-	28162770	TF1	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	NaN	[NaN]	[86]	1	hSpCas9	negative selection	10383413
64496662	64496685	17	+	28162770	TF1	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	NaN	[NaN]	[88]	1	hSpCas9	negative selection	10383414
64496611	64496634	17	-	28162770	TF1	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10383415
64496584	64496607	17	-	28162770	TF1	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10383416
64496554	64496577	17	+	28162770	TF1	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10383417
64496538	64496561	17	+	28162770	TF1	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	NaN	[NaN]	[78]	1	hSpCas9	negative selection	10383418
64492710	64492733	17	+	28162770	TF1	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10383419
64485804	64485827	17	-	28162770	SKM1	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-0.37454272105078423	[43]	[59]	-3	hSpCas9	negative selection	10552776
64492693	64492716	17	+	28162770	SKM1	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-5.303128387758622	[66]	[2]	-9	hSpCas9	negative selection	10552777
64496844	64496867	17	-	28162770	SKM1	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-2.316766389771584	[61]	[21]	-8	hSpCas9	negative selection	10552778
64496824	64496847	17	-	28162770	SKM1	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-2.406964198743162	[44]	[14]	-8	hSpCas9	negative selection	10552779
64496662	64496685	17	+	28162770	SKM1	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-1.6171819061335073	[58]	[33]	-8	hSpCas9	negative selection	10552780
64496611	64496634	17	-	28162770	SKM1	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-1.0244945619207486	[83]	[72]	-6	hSpCas9	negative selection	10552781
64496584	64496607	17	-	28162770	SKM1	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-1.143929792909368	[4]	[3]	-7	hSpCas9	negative selection	10552782
64496554	64496577	17	+	28162770	SKM1	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-1.2179303743531444	[74]	[56]	-7	hSpCas9	negative selection	10552783
64496538	64496561	17	+	28162770	SKM1	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-0.5224414161630978	[64]	[79]	-4	hSpCas9	negative selection	10552784
64492710	64492733	17	+	28162770	SKM1	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-2.7713756249520376	[111]	[28]	-9	hSpCas9	negative selection	10552785
64485804	64485827	17	-	28162770	SKM1	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-0.37454272105078423	[43]	[59]	-3	hSpCas9	negative selection	10722142
64492693	64492716	17	+	28162770	SKM1	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-5.303128387758622	[66]	[2]	-9	hSpCas9	negative selection	10722143
64496844	64496867	17	-	28162770	SKM1	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-2.316766389771584	[61]	[21]	-8	hSpCas9	negative selection	10722144
64496824	64496847	17	-	28162770	SKM1	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-2.406964198743162	[44]	[14]	-8	hSpCas9	negative selection	10722145
64496662	64496685	17	+	28162770	SKM1	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-1.6171819061335073	[58]	[33]	-8	hSpCas9	negative selection	10722146
64496611	64496634	17	-	28162770	SKM1	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-1.0244945619207486	[83]	[72]	-6	hSpCas9	negative selection	10722147
64496584	64496607	17	-	28162770	SKM1	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-1.143929792909368	[4]	[3]	-7	hSpCas9	negative selection	10722148
64496554	64496577	17	+	28162770	SKM1	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-1.2179303743531444	[74]	[56]	-7	hSpCas9	negative selection	10722149
64496538	64496561	17	+	28162770	SKM1	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-0.5224414161630978	[64]	[79]	-4	hSpCas9	negative selection	10722150
64492710	64492733	17	+	28162770	SKM1	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-2.7713756249520376	[111]	[28]	-9	hSpCas9	negative selection	10722151
64485804	64485827	17	-	28162770	PL21	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-2.2852872126809216	[223]	[19]	-8	hSpCas9	negative selection	10891508
64492693	64492716	17	+	28162770	PL21	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-2.0028004441809553	[220]	[23]	-8	hSpCas9	negative selection	10891509
64496844	64496867	17	-	28162770	PL21	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-1.870249713402078	[167]	[19]	-8	hSpCas9	negative selection	10891510
64496824	64496847	17	-	28162770	PL21	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-1.1757272875088458	[108]	[20]	-7	hSpCas9	negative selection	10891511
64496662	64496685	17	+	28162770	PL21	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-0.25417303352296383	[210]	[76]	-2	hSpCas9	negative selection	10891512
64496611	64496634	17	-	28162770	PL21	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-1.2635165900097025	[170]	[30]	-7	hSpCas9	negative selection	10891513
64496584	64496607	17	-	28162770	PL21	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	0.20013961448931994	[3]	[1]	1	hSpCas9	negative selection	10891514
64496554	64496577	17	+	28162770	PL21	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-0.5292127955670108	[251]	[75]	-4	hSpCas9	negative selection	10891515
64496538	64496561	17	+	28162770	PL21	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	0.4585647670705244	[208]	[124]	4	hSpCas9	negative selection	10891516
64492710	64492733	17	+	28162770	PL21	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-3.352642480482686	[398]	[16]	-9	hSpCas9	negative selection	10891517
64485804	64485827	17	-	28162770	P31FUJ	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-2.3736647402542284	[171]	[38]	-8	hSpCas9	negative selection	11060874
64492693	64492716	17	+	28162770	P31FUJ	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-6.529259611785623	[392]	[4]	-9	hSpCas9	negative selection	11060875
64496844	64496867	17	-	28162770	P31FUJ	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-1.4333351917870871	[130]	[56]	-7	hSpCas9	negative selection	11060876
64496824	64496847	17	-	28162770	P31FUJ	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-2.455194625750827	[125]	[26]	-8	hSpCas9	negative selection	11060877
64496662	64496685	17	+	28162770	P31FUJ	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-2.380700899526692	[194]	[43]	-8	hSpCas9	negative selection	11060878
64496611	64496634	17	-	28162770	P31FUJ	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-1.8957672171368078	[227]	[71]	-8	hSpCas9	negative selection	11060879
64496584	64496607	17	-	28162770	P31FUJ	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-5.186998514801253	[30]	[0]	-9	hSpCas9	negative selection	11060880
64496554	64496577	17	+	28162770	P31FUJ	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-0.34918138812870725	[399]	[368]	-3	hSpCas9	negative selection	11060881
64496538	64496561	17	+	28162770	P31FUJ	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-1.7346829636409797	[387]	[136]	-8	hSpCas9	negative selection	11060882
64492710	64492733	17	+	28162770	P31FUJ	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-3.791069838470115	[588]	[49]	-9	hSpCas9	negative selection	11060883
64485804	64485827	17	-	28162770	OCIAML5	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-1.9004295924253962	[90]	[43]	-7	hSpCas9	negative selection	11230240
64492693	64492716	17	+	28162770	OCIAML5	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-6.130051318163762	[193]	[4]	-9	hSpCas9	negative selection	11230241
64496844	64496867	17	-	28162770	OCIAML5	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-2.0855567010837754	[86]	[36]	-8	hSpCas9	negative selection	11230242
64496824	64496847	17	-	28162770	OCIAML5	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-1.5945703485716332	[86]	[51]	-7	hSpCas9	negative selection	11230243
64496662	64496685	17	+	28162770	OCIAML5	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-0.8520665708639967	[121]	[121]	-5	hSpCas9	negative selection	11230244
64496611	64496634	17	-	28162770	OCIAML5	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-1.827404516629728	[115]	[58]	-7	hSpCas9	negative selection	11230245
64496584	64496607	17	-	28162770	OCIAML5	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-4.311498189501295	[10]	[0]	-9	hSpCas9	negative selection	11230246
64496554	64496577	17	+	28162770	OCIAML5	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-2.084013298913694	[201]	[85]	-8	hSpCas9	negative selection	11230247
64496538	64496561	17	+	28162770	OCIAML5	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-1.8451138102222302	[206]	[103]	-7	hSpCas9	negative selection	11230248
64492710	64492733	17	+	28162770	OCIAML5	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-3.470195935520352	[263]	[42]	-9	hSpCas9	negative selection	11230249
64485804	64485827	17	-	28162770	EOL1	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-2.3472568438909915	[395]	[40]	-8	hSpCas9	negative selection	11399606
64492693	64492716	17	+	28162770	EOL1	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-3.5261136374390305	[327]	[14]	-9	hSpCas9	negative selection	11399607
64496844	64496867	17	-	28162770	EOL1	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-1.4021813095806488	[300]	[59]	-7	hSpCas9	negative selection	11399608
64496824	64496847	17	-	28162770	EOL1	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-1.3973803233168278	[219]	[43]	-7	hSpCas9	negative selection	11399609
64496662	64496685	17	+	28162770	EOL1	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-1.5502318114001987	[377]	[67]	-7	hSpCas9	negative selection	11399610
64496611	64496634	17	-	28162770	EOL1	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-1.918519247206473	[408]	[56]	-8	hSpCas9	negative selection	11399611
64496584	64496607	17	-	28162770	EOL1	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-2.9823428240379837	[14]	[0]	-9	hSpCas9	negative selection	11399612
64496554	64496577	17	+	28162770	EOL1	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-1.6564675446339587	[364]	[60]	-8	hSpCas9	negative selection	11399613
64496538	64496561	17	+	28162770	EOL1	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-1.7193084182041902	[324]	[51]	-8	hSpCas9	negative selection	11399614
64492710	64492733	17	+	28162770	EOL1	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	2.430976869745001	[603]	[1715]	9	hSpCas9	negative selection	11399615
64485804	64485827	17	-	28162770	MOLM13	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-2.647587835875357	[233]	[26]	-8	hSpCas9	negative selection	11568972
64492693	64492716	17	+	28162770	MOLM13	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-2.9426326366117723	[318]	[29]	-8	hSpCas9	negative selection	11568973
64496844	64496867	17	-	28162770	MOLM13	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-0.3361904084801641	[219]	[125]	-2	hSpCas9	negative selection	11568974
64496824	64496847	17	-	28162770	MOLM13	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-0.9787937443507303	[168]	[61]	-5	hSpCas9	negative selection	11568975
64496662	64496685	17	+	28162770	MOLM13	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-0.8727926734081458	[270]	[106]	-5	hSpCas9	negative selection	11568976
64496611	64496634	17	-	28162770	MOLM13	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-0.8010456257288994	[293]	[121]	-4	hSpCas9	negative selection	11568977
64496584	64496607	17	-	28162770	MOLM13	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-3.780038131899007	[18]	[0]	-9	hSpCas9	negative selection	11568978
64496554	64496577	17	+	28162770	MOLM13	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-2.8785610324768527	[355]	[34]	-8	hSpCas9	negative selection	11568979
64496538	64496561	17	+	28162770	MOLM13	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-0.886643378774711	[357]	[139]	-5	hSpCas9	negative selection	11568980
64492710	64492733	17	+	28162770	MOLM13	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-3.5479355856171035	[549]	[33]	-8	hSpCas9	negative selection	11568981
64485804	64485827	17	-	28162770	HEL	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-7.071506685665765	[209]	[0]	-9	hSpCas9	negative selection	11738338
64492693	64492716	17	+	28162770	HEL	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-4.880823124056656	[275]	[5]	-9	hSpCas9	negative selection	11738339
64496844	64496867	17	-	28162770	HEL	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-3.4447240092499825	[220]	[12]	-9	hSpCas9	negative selection	11738340
64496824	64496847	17	-	28162770	HEL	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-1.057700886140735	[168]	[51]	-6	hSpCas9	negative selection	11738341
64496662	64496685	17	+	28162770	HEL	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-0.7585117155484113	[242]	[91]	-5	hSpCas9	negative selection	11738342
64496611	64496634	17	-	28162770	HEL	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-1.218387346498228	[286]	[78]	-6	hSpCas9	negative selection	11738343
64496584	64496607	17	-	28162770	HEL	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-2.8166927866369402	[10]	[0]	-8	hSpCas9	negative selection	11738344
64496554	64496577	17	+	28162770	HEL	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-2.8210579791983426	[330]	[29]	-8	hSpCas9	negative selection	11738345
64496538	64496561	17	+	28162770	HEL	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	0.1412613167822821	[234]	[165]	1	hSpCas9	negative selection	11738346
64492710	64492733	17	+	28162770	HEL	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-3.8353084648042874	[467]	[20]	-9	hSpCas9	negative selection	11738347
64485804	64485827	17	-	28162770	MV411	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-2.7998681639955816	[247]	[29]	-9	hSpCas9	negative selection	11907704
64492693	64492716	17	+	28162770	MV411	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-7.802410998667787	[264]	[0]	-9	hSpCas9	negative selection	11907705
64496844	64496867	17	-	28162770	MV411	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-1.7443419424122562	[174]	[43]	-8	hSpCas9	negative selection	11907706
64496824	64496847	17	-	28162770	MV411	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-1.1287109351024736	[121]	[46]	-6	hSpCas9	negative selection	11907707
64496662	64496685	17	+	28162770	MV411	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-2.0281968918306523	[183]	[37]	-8	hSpCas9	negative selection	11907708
64496611	64496634	17	-	28162770	MV411	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-0.7094937273253386	[197]	[101]	-5	hSpCas9	negative selection	11907709
64496584	64496607	17	-	28162770	MV411	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-3.840025290467564	[16]	[0]	-9	hSpCas9	negative selection	11907710
64496554	64496577	17	+	28162770	MV411	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-1.9274881317179036	[288]	[63]	-8	hSpCas9	negative selection	11907711
64496538	64496561	17	+	28162770	MV411	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-0.585267703819584	[243]	[136]	-4	hSpCas9	negative selection	11907712
64492710	64492733	17	+	28162770	MV411	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-2.4713806966731715	[394]	[59]	-8	hSpCas9	negative selection	11907713
64485804	64485827	17	-	28162770	MONOMAC1	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-1.7819993477807101	[98]	[32]	-8	hSpCas9	negative selection	12077070
64492693	64492716	17	+	28162770	MONOMAC1	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-2.667356781839587	[132]	[23]	-9	hSpCas9	negative selection	12077071
64496844	64496867	17	-	28162770	MONOMAC1	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-0.48826814472399954	[92]	[75]	-4	hSpCas9	negative selection	12077072
64496824	64496847	17	-	28162770	MONOMAC1	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-1.151233157446429	[61]	[31]	-7	hSpCas9	negative selection	12077073
64496662	64496685	17	+	28162770	MONOMAC1	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-0.9300979867698438	[122]	[73]	-6	hSpCas9	negative selection	12077074
64496611	64496634	17	-	28162770	MONOMAC1	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	0.002732665316223626	[100]	[115]	0	hSpCas9	negative selection	12077075
64496584	64496607	17	-	28162770	MONOMAC1	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-3.366961848501866	[8]	[0]	-9	hSpCas9	negative selection	12077076
64496554	64496577	17	+	28162770	MONOMAC1	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-1.9510184182413615	[198]	[58]	-8	hSpCas9	negative selection	12077077
64496538	64496561	17	+	28162770	MONOMAC1	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-2.097041057082832	[208]	[55]	-9	hSpCas9	negative selection	12077078
64492710	64492733	17	+	28162770	MONOMAC1	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-3.234791769054972	[270]	[32]	-9	hSpCas9	negative selection	12077079
64485804	64485827	17	-	28162770	OCIAML2	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-2.314510623324879	[34]	[38]	-8	hSpCas9	negative selection	12246436
64492693	64492716	17	+	28162770	OCIAML2	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-3.9300614438794588	[43]	[15]	-9	hSpCas9	negative selection	12246437
64496844	64496867	17	-	28162770	OCIAML2	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-1.927487500215632	[34]	[50]	-8	hSpCas9	negative selection	12246438
64496824	64496847	17	-	28162770	OCIAML2	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-2.5961607073260202	[23]	[21]	-8	hSpCas9	negative selection	12246439
64496662	64496685	17	+	28162770	OCIAML2	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-2.068531381670816	[27]	[36]	-8	hSpCas9	negative selection	12246440
64496611	64496634	17	-	28162770	OCIAML2	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-0.1743883740184483	[33]	[166]	-1	hSpCas9	negative selection	12246441
64496584	64496607	17	-	28162770	OCIAML2	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-4.0555923259633175	[2]	[0]	-9	hSpCas9	negative selection	12246442
64496554	64496577	17	+	28162770	OCIAML2	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-1.9512556661485818	[59]	[85]	-8	hSpCas9	negative selection	12246443
64496538	64496561	17	+	28162770	OCIAML2	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-1.5598971633392484	[49]	[93]	-7	hSpCas9	negative selection	12246444
64492710	64492733	17	+	28162770	OCIAML2	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-5.214790920812571	[66]	[9]	-9	hSpCas9	negative selection	12246445
64485804	64485827	17	-	28162770	OCIAML3	viability	GTAAATGGGGACCTAGACCGAGG	POLG2	ENSG00000256525	-2.111855945186782	[62]	[43]	-8	hSpCas9	negative selection	12415802
64492693	64492716	17	+	28162770	OCIAML3	viability	GTAACCAGAAATCAAGCCACTGG	POLG2	ENSG00000256525	-5.963241449989883	[61]	[2]	-9	hSpCas9	negative selection	12415803
64496844	64496867	17	-	28162770	OCIAML3	viability	GAAAGGAGTAGCCCCAAAGGAGG	POLG2	ENSG00000256525	-0.4335429681309171	[33]	[75]	-3	hSpCas9	negative selection	12415804
64496824	64496847	17	-	28162770	OCIAML3	viability	AGGGCATGTGAAGTCGCACGCGG	POLG2	ENSG00000256525	-4.072054937128807	[38]	[6]	-9	hSpCas9	negative selection	12415805
64496662	64496685	17	+	28162770	OCIAML3	viability	CCAAGGGTCCGAAGCCGGGGTGG	POLG2	ENSG00000256525	-1.2785058145962338	[44]	[55]	-7	hSpCas9	negative selection	12415806
64496611	64496634	17	-	28162770	OCIAML3	viability	AGAATGGTGGACCTCGGTGGTGG	POLG2	ENSG00000256525	-0.717155871097028	[54]	[100]	-5	hSpCas9	negative selection	12415807
64496584	64496607	17	-	28162770	OCIAML3	viability	CAGGGAGCAGGTATTCCCGGTGG	POLG2	ENSG00000256525	-3.17897014104532	[2]	[0]	-9	hSpCas9	negative selection	12415808
64496554	64496577	17	+	28162770	OCIAML3	viability	GCAAAGGGCCTGGTTTGTGGTGG	POLG2	ENSG00000256525	-1.3045010231291783	[116]	[142]	-7	hSpCas9	negative selection	12415809
64496538	64496561	17	+	28162770	OCIAML3	viability	GCACTGTCCCCGGGTAGCAAAGG	POLG2	ENSG00000256525	-0.5620647478214089	[66]	[136]	-4	hSpCas9	negative selection	12415810
64492710	64492733	17	+	28162770	OCIAML3	viability	CACTGGTTTGAAGTTCTCGGAGG	POLG2	ENSG00000256525	-4.256972653046592	[113]	[17]	-9	hSpCas9	negative selection	12415811