Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5429
• Symbol: POLH
• Description: DNA polymerase eta

DataSource: http://genomecrispr.dkfz.de/#!/results/POLH

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
43597802	43597825	6	+	26472758	Jiyoye	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	-0.26420187103275583	[171]	[107]	-2	hSpCas9	negative selection	123480
43583117	43583140	6	-	26472758	Jiyoye	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-0.08296357301368895	[183]	[130]	0	hSpCas9	negative selection	123481
43603894	43603917	6	+	26472758	Jiyoye	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	-0.38946538932028085	[435]	[250]	-3	hSpCas9	negative selection	123482
43604683	43604706	6	-	26472758	Jiyoye	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	0.9387884576340958	[100]	[145]	6	hSpCas9	negative selection	123483
43583101	43583124	6	+	26472758	Jiyoye	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	0.5002847858973548	[59]	[63]	4	hSpCas9	negative selection	123484
43597751	43597774	6	-	26472758	Jiyoye	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-1.4371737480339326	[78]	[21]	-7	hSpCas9	negative selection	123485
43597778	43597801	6	+	26472758	Jiyoye	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	0.9793592775057269	[188]	[280]	6	hSpCas9	negative selection	123486
43601057	43601080	6	-	26472758	Jiyoye	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	1.1937717433966801	[39]	[68]	7	hSpCas9	negative selection	123487
43604647	43604670	6	+	26472758	Jiyoye	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	-0.3297902126603328	[254]	[152]	-2	hSpCas9	negative selection	123488
43605262	43605285	6	+	26472758	Jiyoye	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	0.041525909189192856	[66]	[51]	0	hSpCas9	negative selection	123489
43597802	43597825	6	+	26472758	KBM7	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	0.047489909579016	[366,322]	[235,105]	0	hSpCas9	negative selection	314598
43583117	43583140	6	-	26472758	KBM7	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-0.8651355395156328	[1011,786]	[270,193]	-6	hSpCas9	negative selection	314599
43603894	43603917	6	+	26472758	KBM7	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	-0.009270983232703145	[1167,1102]	[521,539]	0	hSpCas9	negative selection	314600
43604683	43604706	6	-	26472758	KBM7	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	0.46457078182322437	[592,400]	[342,294]	5	hSpCas9	negative selection	314601
43583101	43583124	6	+	26472758	KBM7	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	0.09696977485284197	[282,200]	[163,80]	0	hSpCas9	negative selection	314602
43597751	43597774	6	-	26472758	KBM7	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-0.9618876957849333	[504,320]	[127,70]	-6	hSpCas9	negative selection	314603
43597778	43597801	6	+	26472758	KBM7	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	-0.06788749128716676	[1040,1267]	[702,366]	0	hSpCas9	negative selection	314604
43601057	43601080	6	-	26472758	KBM7	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	-0.44401237840400665	[441,187]	[115,94]	-4	hSpCas9	negative selection	314605
43604647	43604670	6	+	26472758	KBM7	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	-0.021818743059994206	[729,880]	[388,368]	0	hSpCas9	negative selection	314606
43605262	43605285	6	+	26472758	KBM7	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	-0.0015155320447431953	[421,292]	[181,150]	0	hSpCas9	negative selection	314607
43597802	43597825	6	+	26472758	Raji	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	0.5520462037617216	[240]	[81]	5	hSpCas9	negative selection	505716
43583117	43583140	6	-	26472758	Raji	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-1.294714908197746	[443]	[41]	-7	hSpCas9	negative selection	505717
43603894	43603917	6	+	26472758	Raji	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	-0.12708171826342363	[479]	[101]	-1	hSpCas9	negative selection	505718
43604683	43604706	6	-	26472758	Raji	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	-0.234084745909408	[222]	[43]	-2	hSpCas9	negative selection	505719
43583101	43583124	6	+	26472758	Raji	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	-0.6100292613712062	[170]	[25]	-5	hSpCas9	negative selection	505720
43597751	43597774	6	-	26472758	Raji	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-4.140543978069987	[227]	[2]	-9	hSpCas9	negative selection	505721
43597778	43597801	6	+	26472758	Raji	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	-0.1345050615886456	[595]	[125]	-1	hSpCas9	negative selection	505722
43601057	43601080	6	-	26472758	Raji	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	0.3159701571850168	[179]	[51]	3	hSpCas9	negative selection	505723
43604647	43604670	6	+	26472758	Raji	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	-0.3951168051555839	[458]	[80]	-3	hSpCas9	negative selection	505724
43605262	43605285	6	+	26472758	Raji	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	-1.231753849545986	[252]	[24]	-7	hSpCas9	negative selection	505725
43597802	43597825	6	+	26472758	K562	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	-0.17234345208185792	[278]	[208]	-1	hSpCas9	negative selection	696834
43583117	43583140	6	-	26472758	K562	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-1.5500705676207351	[613]	[176]	-6	hSpCas9	negative selection	696835
43603894	43603917	6	+	26472758	K562	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	-0.03409378000190166	[1161]	[957]	0	hSpCas9	negative selection	696836
43604683	43604706	6	-	26472758	K562	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	-0.1492451208198299	[334]	[254]	-1	hSpCas9	negative selection	696837
43583101	43583124	6	+	26472758	K562	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	0.6790469553031713	[127]	[172]	5	hSpCas9	negative selection	696838
43597751	43597774	6	-	26472758	K562	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-4.198524768182281	[347]	[15]	-9	hSpCas9	negative selection	696839
43597778	43597801	6	+	26472758	K562	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	-1.0788892764996116	[1045]	[417]	-5	hSpCas9	negative selection	696840
43601057	43601080	6	-	26472758	K562	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	1.0282101779533714	[193]	[333]	8	hSpCas9	negative selection	696841
43604647	43604670	6	+	26472758	K562	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	-0.6844076579097178	[612]	[321]	-4	hSpCas9	negative selection	696842
43605262	43605285	6	+	26472758	K562	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	-0.42151261457397876	[283]	[178]	-3	hSpCas9	negative selection	696843
43582340	43582363	6	+	26627737	DLD1	viability	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-0.04293897829358858	[487]	[159,218,78]	0	hSpCas9	negative selection	833135
43597809	43597832	6	+	26627737	DLD1	viability	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	-0.21324731024978696	[545]	[86,253,110]	-2	hSpCas9	negative selection	833136
43601017	43601040	6	+	26627737	DLD1	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.502817449740764	[1602]	[233,417,403]	-5	hSpCas9	negative selection	833137
43603918	43603941	6	-	26627737	DLD1	viability	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.33287748495709946	[1362]	[374,275,357]	-3	hSpCas9	negative selection	833138
43604717	43604740	6	+	26627737	DLD1	viability	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-0.062308425686248274	[459]	[57,157,189]	0	hSpCas9	negative selection	833139
43582340	43582363	6	+	26627737	GBM cells	viability after 5 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-0.6997235627325471	[158]	[36,67]	-8	hSpCas9	negative selection	915450
43597809	43597832	6	+	26627737	GBM cells	viability after 5 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	0.78899618280765	[258]	[241,237]	9	hSpCas9	negative selection	915451
43601017	43601040	6	+	26627737	GBM cells	viability after 5 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.18830296158259463	[732]	[335,353]	-3	hSpCas9	negative selection	915452
43603918	43603941	6	-	26627737	GBM cells	viability after 5 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.4272142085309625	[859]	[319,365]	-6	hSpCas9	negative selection	915453
43604717	43604740	6	+	26627737	GBM cells	viability after 5 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-0.003651974208687736	[228]	[145,98]	0	hSpCas9	negative selection	915454
43582340	43582363	6	+	26627737	GBM cells	viability after 13 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-0.0606052919644855	[158]	[74,88]	0	hSpCas9	negative selection	997765
43597809	43597832	6	+	26627737	GBM cells	viability after 13 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	1.070009810961304	[258]	[358,242]	9	hSpCas9	negative selection	997766
43601017	43601040	6	+	26627737	GBM cells	viability after 13 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	0.09876978435869743	[732]	[485,376]	1	hSpCas9	negative selection	997767
43603918	43603941	6	-	26627737	GBM cells	viability after 13 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.4807348251693113	[859]	[340,328]	-5	hSpCas9	negative selection	997768
43604717	43604740	6	+	26627737	GBM cells	viability after 13 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-0.32421235346863353	[228]	[101,96]	-4	hSpCas9	negative selection	997769
43582340	43582363	6	+	26627737	GBM cells	viability after 21 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-0.3739964358282677	[158]	[62,69]	-3	hSpCas9	negative selection	1080080
43597809	43597832	6	+	26627737	GBM cells	viability after 21 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	0.8504679043689181	[258]	[283,225]	8	hSpCas9	negative selection	1080081
43601017	43601040	6	+	26627737	GBM cells	viability after 21 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	0.056205739363037965	[732]	[412,414]	0	hSpCas9	negative selection	1080082
43603918	43603941	6	-	26627737	GBM cells	viability after 21 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.5573972572131534	[859]	[352,284]	-5	hSpCas9	negative selection	1080083
43604717	43604740	6	+	26627737	GBM cells	viability after 21 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-0.9522236560407005	[228]	[68,59]	-7	hSpCas9	negative selection	1080084
43582340	43582363	6	+	26627737	RPE1	viability after 9 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-1.2148105554556454	[882]	[105,135]	-7	hSpCas9	negative selection	1162395
43597809	43597832	6	+	26627737	RPE1	viability after 9 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	1.5450197631855709	[400]	[409,309]	8	hSpCas9	negative selection	1162396
43601017	43601040	6	+	26627737	RPE1	viability after 9 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-2.6009718258183776	[4026]	[171,253]	-9	hSpCas9	negative selection	1162397
43603918	43603941	6	-	26627737	RPE1	viability after 9 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-1.3582226156685466	[2677]	[278,388]	-7	hSpCas9	negative selection	1162398
43604717	43604740	6	+	26627737	RPE1	viability after 9 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-1.29644049704737	[966]	[93,160]	-7	hSpCas9	negative selection	1162399
43582340	43582363	6	+	26627737	RPE1	viability after 12 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-1.7380907179392588	[882]	[108,30]	-8	hSpCas9	negative selection	1244710
43597809	43597832	6	+	26627737	RPE1	viability after 12 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	1.3014538977839756	[400]	[300,227]	7	hSpCas9	negative selection	1244711
43601017	43601040	6	+	26627737	RPE1	viability after 12 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-1.9911579849495358	[4026]	[225,320]	-8	hSpCas9	negative selection	1244712
43603918	43603941	6	-	26627737	RPE1	viability after 12 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.9871166534531814	[2677]	[242,489]	-6	hSpCas9	negative selection	1244713
43604717	43604740	6	+	26627737	RPE1	viability after 12 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-1.4887655869766827	[966]	[43,143]	-7	hSpCas9	negative selection	1244714
43582340	43582363	6	+	26627737	RPE1	viability after 15 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-0.6819040050066449	[882]	[256,57]	-4	hSpCas9	negative selection	1327025
43597809	43597832	6	+	26627737	RPE1	viability after 15 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	0.9387868151176096	[400]	[304,132]	5	hSpCas9	negative selection	1327026
43601017	43601040	6	+	26627737	RPE1	viability after 15 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-1.7605591436042807	[4026]	[352,319]	-8	hSpCas9	negative selection	1327027
43603918	43603941	6	-	26627737	RPE1	viability after 15 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-1.6625911699792908	[2677]	[194,281]	-7	hSpCas9	negative selection	1327028
43604717	43604740	6	+	26627737	RPE1	viability after 15 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-2.15592433782715	[966]	[39,81]	-8	hSpCas9	negative selection	1327029
43582340	43582363	6	+	26627737	RPE1	viability after 18 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-1.267797371862092	[882]	[126,68]	-7	hSpCas9	negative selection	1409340
43597809	43597832	6	+	26627737	RPE1	viability after 18 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	1.4307928203719027	[400]	[298,283]	7	hSpCas9	negative selection	1409341
43601017	43601040	6	+	26627737	RPE1	viability after 18 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-2.783772779659171	[4026]	[93,225]	-9	hSpCas9	negative selection	1409342
43603918	43603941	6	-	26627737	RPE1	viability after 18 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-1.1412216583410197	[2677]	[273,384]	-6	hSpCas9	negative selection	1409343
43604717	43604740	6	+	26627737	RPE1	viability after 18 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-1.8530384080668854	[966]	[49,95]	-8	hSpCas9	negative selection	1409344
43582340	43582363	6	+	26627737	HeLa	viability after 8 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-0.9432074799723	[291]	[103,12,87]	-7	hSpCas9	negative selection	1491655
43597809	43597832	6	+	26627737	HeLa	viability after 8 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	0.1698231734619372	[595]	[180,261,399]	1	hSpCas9	negative selection	1491656
43601017	43601040	6	+	26627737	HeLa	viability after 8 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.8895566684520478	[1122]	[326,151,321]	-7	hSpCas9	negative selection	1491657
43603918	43603941	6	-	26627737	HeLa	viability after 8 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.6691235540042734	[986]	[414,198,230]	-6	hSpCas9	negative selection	1491658
43604717	43604740	6	+	26627737	HeLa	viability after 8 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	0.315005484659838	[291]	[110,300,58]	3	hSpCas9	negative selection	1491659
43582340	43582363	6	+	26627737	HeLa	viability after 12 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-1.4990086476544653	[291]	[40,42,43]	-8	hSpCas9	negative selection	1573970
43597809	43597832	6	+	26627737	HeLa	viability after 12 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	0.18632515037394393	[595]	[338,199,311]	1	hSpCas9	negative selection	1573971
43601017	43601040	6	+	26627737	HeLa	viability after 12 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.07177287404815802	[1122]	[541,390,399]	0	hSpCas9	negative selection	1573972
43603918	43603941	6	-	26627737	HeLa	viability after 12 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-1.0645797090668248	[986]	[354,78,167]	-7	hSpCas9	negative selection	1573973
43604717	43604740	6	+	26627737	HeLa	viability after 12 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	0.30052956511700346	[291]	[148,137,159]	2	hSpCas9	negative selection	1573974
43582340	43582363	6	+	26627737	HeLa	viability after 15 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-1.3121563444317823	[291]	[29,39,75]	-8	hSpCas9	negative selection	1656285
43597809	43597832	6	+	26627737	HeLa	viability after 15 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	0.40941625614107147	[595]	[122,358,500]	3	hSpCas9	negative selection	1656286
43601017	43601040	6	+	26627737	HeLa	viability after 15 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.022835781438636182	[1122]	[329,408,625]	0	hSpCas9	negative selection	1656287
43603918	43603941	6	-	26627737	HeLa	viability after 15 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.2027667282261203	[986]	[473,86,495]	-2	hSpCas9	negative selection	1656288
43604717	43604740	6	+	26627737	HeLa	viability after 15 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	0.49845873095207177	[291]	[193,122,187]	4	hSpCas9	negative selection	1656289
43582340	43582363	6	+	26627737	HeLa	viability after 18 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-1.2879720544419135	[291]	[20,33,75]	-8	hSpCas9	negative selection	1738600
43597809	43597832	6	+	26627737	HeLa	viability after 18 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	0.39382447372491347	[595]	[79,291,500]	3	hSpCas9	negative selection	1738601
43601017	43601040	6	+	26627737	HeLa	viability after 18 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.04467291737976731	[1122]	[219,323,625]	0	hSpCas9	negative selection	1738602
43603918	43603941	6	-	26627737	HeLa	viability after 18 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.18098532790463429	[986]	[325,74,495]	-1	hSpCas9	negative selection	1738603
43604717	43604740	6	+	26627737	HeLa	viability after 18 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	0.4313565936574234	[291]	[123,90,187]	3	hSpCas9	negative selection	1738604
43582340	43582363	6	+	26627737	HCT116	viability after 6 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-2.0141667085613975	[514]	[30,13]	-8	hSpCas9	negative selection	1820915
43597809	43597832	6	+	26627737	HCT116	viability after 6 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	-0.27826265192206207	[908]	[180,82]	-1	hSpCas9	negative selection	1820916
43601017	43601040	6	+	26627737	HCT116	viability after 6 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.45745258635722763	[1722]	[204,192]	-3	hSpCas9	negative selection	1820917
43603918	43603941	6	-	26627737	HCT116	viability after 6 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.9139837263072899	[1677]	[275,64]	-5	hSpCas9	negative selection	1820918
43604717	43604740	6	+	26627737	HCT116	viability after 6 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-0.6214661424766669	[366]	[90,7]	-4	hSpCas9	negative selection	1820919
43582340	43582363	6	+	26627737	HCT116	viability after 8 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	0.3157979528515278	[220]	[138,204,110]	3	hSpCas9	negative selection	1903230
43597809	43597832	6	+	26627737	HCT116	viability after 8 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	0.41133255961084425	[293]	[279,110,255]	4	hSpCas9	negative selection	1903231
43601017	43601040	6	+	26627737	HCT116	viability after 8 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.28109352332199067	[887]	[248,444,509]	-3	hSpCas9	negative selection	1903232
43603918	43603941	6	-	26627737	HCT116	viability after 8 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.4843677525466178	[691]	[310,285,221]	-5	hSpCas9	negative selection	1903233
43604717	43604740	6	+	26627737	HCT116	viability after 8 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-0.20589779790432974	[332]	[164,122,188]	-2	hSpCas9	negative selection	1903234
43582340	43582363	6	+	26627737	HCT116	viability after 9 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-1.6847504574253114	[514]	[63,25]	-8	hSpCas9	negative selection	1985545
43597809	43597832	6	+	26627737	HCT116	viability after 9 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	0.4247439920203001	[908]	[484,199]	3	hSpCas9	negative selection	1985546
43601017	43601040	6	+	26627737	HCT116	viability after 9 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	0.7501031030117171	[1722]	[913,662]	5	hSpCas9	negative selection	1985547
43603918	43603941	6	-	26627737	HCT116	viability after 9 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.7389283451995745	[1677]	[263,271]	-5	hSpCas9	negative selection	1985548
43604717	43604740	6	+	26627737	HCT116	viability after 9 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	0.8622548090615286	[366]	[171,182]	6	hSpCas9	negative selection	1985549
43582340	43582363	6	+	26627737	HCT116	viability after 12 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	0.19650885024829917	[220]	[142,157,97]	2	hSpCas9	negative selection	2067860
43597809	43597832	6	+	26627737	HCT116	viability after 12 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	0.19533545435474486	[293]	[220,141,162]	2	hSpCas9	negative selection	2067861
43601017	43601040	6	+	26627737	HCT116	viability after 12 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.8315872807740514	[887]	[198,293,299]	-7	hSpCas9	negative selection	2067862
43603918	43603941	6	-	26627737	HCT116	viability after 12 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.4163057407957206	[691]	[265,350,202]	-4	hSpCas9	negative selection	2067863
43604717	43604740	6	+	26627737	HCT116	viability after 12 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-0.13957618918192852	[332]	[66,172,244]	-1	hSpCas9	negative selection	2067864
43582340	43582363	6	+	26627737	HCT116	viability after 15 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	0.14584950228742505	[220]	[271,84,80]	1	hSpCas9	negative selection	2150175
43597809	43597832	6	+	26627737	HCT116	viability after 15 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	0.3945080572714306	[293]	[241,181,243]	4	hSpCas9	negative selection	2150176
43601017	43601040	6	+	26627737	HCT116	viability after 15 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.5867366302619296	[887]	[330,292,392]	-6	hSpCas9	negative selection	2150177
43603918	43603941	6	-	26627737	HCT116	viability after 15 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.42993706653315866	[691]	[350,344,196]	-4	hSpCas9	negative selection	2150178
43604717	43604740	6	+	26627737	HCT116	viability after 15 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-0.25528594262162163	[332]	[222,78,185]	-3	hSpCas9	negative selection	2150179
43582340	43582363	6	+	26627737	HCT116	viability after 18 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	0.2323365561591083	[220]	[207,61,109]	2	hSpCas9	negative selection	2232490
43597809	43597832	6	+	26627737	HCT116	viability after 18 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	0.7446461829334248	[293]	[140,341,223]	6	hSpCas9	negative selection	2232491
43601017	43601040	6	+	26627737	HCT116	viability after 18 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.7189450067447717	[887]	[407,289,73]	-6	hSpCas9	negative selection	2232492
43603918	43603941	6	-	26627737	HCT116	viability after 18 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.5796151444785073	[691]	[235,240,191]	-5	hSpCas9	negative selection	2232493
43604717	43604740	6	+	26627737	HCT116	viability after 18 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-0.5934448056900286	[332]	[125,90,103]	-5	hSpCas9	negative selection	2232494
43582322	43582345	6	+	24336569	HL60	viability	GGCTACTGGACAGGATCGAGTGG	POLH	ENSG00000170734	-0.6519561185417195	[619]	[834]	-5	hSpCas9	negative selection	2285004
43582334	43582357	6	+	24336569	HL60	viability	GGATCGAGTGGTTGCTCTCGTGG	POLH	ENSG00000170734	-2.0843351364836513	[502]	[250]	-9	hSpCas9	negative selection	2285005
43582340	43582363	6	+	24336569	HL60	viability	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-0.3419245627988641	[111]	[186]	-3	hSpCas9	negative selection	2285006
43582416	43582439	6	-	24336569	HL60	viability	TTGTACTGTACAACTGCACAAGG	POLH	ENSG00000170734	-0.1866463373209527	[575]	[1070]	-2	hSpCas9	negative selection	2285007
43582423	43582446	6	+	24336569	HL60	viability	CAGTTGTACAGTACAAATCATGG	POLH	ENSG00000170734	0.8123055732461808	[80]	[300]	6	hSpCas9	negative selection	2285008
43582428	43582451	6	+	24336569	HL60	viability	GTACAGTACAAATCATGGAAGGG	POLH	ENSG00000170734	-1.1223363820444245	[357]	[347]	-7	hSpCas9	negative selection	2285009
43582434	43582457	6	+	24336569	HL60	viability	TACAAATCATGGAAGGGTGGTGG	POLH	ENSG00000170734	0.903814393664338	[393]	[1559]	7	hSpCas9	negative selection	2285010
43583020	43583043	6	+	24336569	HL60	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.6964581677601678	[381]	[1309]	6	hSpCas9	negative selection	2285011
43583039	43583062	6	+	24336569	HL60	viability	TTGGAGTCACTAGAAGTATGTGG	POLH	ENSG00000170734	-0.03917691998048212	[352]	[726]	0	hSpCas9	negative selection	2285012
43583079	43583102	6	+	24336569	HL60	viability	GTTATGTCCAGATCTTCTACTGG	POLH	ENSG00000170734	-0.5008145927788227	[334]	[500]	-4	hSpCas9	negative selection	2285013
43582322	43582345	6	+	24336569	KBM7	viability	GGCTACTGGACAGGATCGAGTGG	POLH	ENSG00000170734	-0.6143982871233732	[434]	[774]	-5	hSpCas9	negative selection	2352181
43582334	43582357	6	+	24336569	KBM7	viability	GGATCGAGTGGTTGCTCTCGTGG	POLH	ENSG00000170734	0.5936715317174359	[180]	[744]	5	hSpCas9	negative selection	2352182
43582340	43582363	6	+	24336569	KBM7	viability	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-1.7487487312694472	[68]	[55]	-8	hSpCas9	negative selection	2352183
43582416	43582439	6	-	24336569	KBM7	viability	TTGTACTGTACAACTGCACAAGG	POLH	ENSG00000170734	0.2525917882318556	[412]	[1341]	2	hSpCas9	negative selection	2352184
43582423	43582446	6	+	24336569	KBM7	viability	CAGTTGTACAGTACAAATCATGG	POLH	ENSG00000170734	-1.5281976567571673	[91]	[86]	-7	hSpCas9	negative selection	2352185
43582428	43582451	6	+	24336569	KBM7	viability	GTACAGTACAAATCATGGAAGGG	POLH	ENSG00000170734	-0.2484234837828158	[303]	[697]	-2	hSpCas9	negative selection	2352186
43582434	43582457	6	+	24336569	KBM7	viability	TACAAATCATGGAAGGGTGGTGG	POLH	ENSG00000170734	0.7929280193471699	[553]	[2617]	7	hSpCas9	negative selection	2352187
43583020	43583043	6	+	24336569	KBM7	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.9625862275628023	[240]	[1280]	8	hSpCas9	negative selection	2352188
43583039	43583062	6	+	24336569	KBM7	viability	TTGGAGTCACTAGAAGTATGTGG	POLH	ENSG00000170734	0.6845243394584626	[364]	[1599]	6	hSpCas9	negative selection	2352189
43583079	43583102	6	+	24336569	KBM7	viability	GTTATGTCCAGATCTTCTACTGG	POLH	ENSG00000170734	-0.10681942693114843	[273]	[693]	-1	hSpCas9	negative selection	2352190
43576213	43576236	6	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCTCTCGTCTGATCCCTGCTGG	POLH	ENSG00000170734	-0.18488132172277227	[401,28]	[63,14]	0	dCas9-VP64	positive selection	2452352
43576245	43576268	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	GATCGTAAAGGATCCTGCCCGGG	POLH	ENSG00000170734	3.1064196465857465	[44,24]	[107,21]	8	dCas9-VP64	positive selection	2452353
43576181	43576204	6	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAATGCAGCCGCCAGACTGAGG	POLH	ENSG00000170734	1.2869159472376426	[102,2]	[33,20]	5	dCas9-VP64	positive selection	2452354
43576213	43576236	6	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCTCTCGTCTGATCCCTGCTGG	POLH	ENSG00000170734	0.5991694155105629	[126,286]	[176,29]	4	dCas9-VP64	positive selection	2547607
43576245	43576268	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	GATCGTAAAGGATCCTGCCCGGG	POLH	ENSG00000170734	0.03875435598943286	[93,163]	[36,47]	0	dCas9-VP64	positive selection	2547608
43576181	43576204	6	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAATGCAGCCGCCAGACTGAGG	POLH	ENSG00000170734	-0.6208321564780248	[97,76]	[21,14]	-6	dCas9-VP64	positive selection	2547609
43603892	43603915	6	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTAGCTTTCCTCCAAGACTACGG	POLH	ENSG00000170734	-0.08287344729956164	[3,3]	[2,2]	-1	hSpCas9	positive selection	3012412
43601029	43601052	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCAAACCCTGGTTTCACATGGG	POLH	ENSG00000170734	-0.09689828598151051	[4,4]	[4,3]	-1	hSpCas9	positive selection	3012413
43603895	43603918	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	0.0005202380417820562	[3,3]	[3,2]	0	hSpCas9	positive selection	3012414
43587447	43587470	6	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGCCCCAAGGCCCTACAACGG	POLH	ENSG00000170734	-0.10598400336257519	[2,2]	[2,1]	-1	hSpCas9	positive selection	3012415
43603892	43603915	6	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTAGCTTTCCTCCAAGACTACGG	POLH	ENSG00000170734	-0.1010951845592308	[3,3]	[2,2]	-1	hSpCas9	positive selection	3080270
43601029	43601052	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCAAACCCTGGTTTCACATGGG	POLH	ENSG00000170734	-0.28999265760582826	[4,4]	[4,1]	-4	hSpCas9	positive selection	3080271
43603895	43603918	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	0.18839811541475762	[3,3]	[2,3]	3	hSpCas9	positive selection	3080272
43587447	43587470	6	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGCCCCAAGGCCCTACAACGG	POLH	ENSG00000170734	-0.09849248564553736	[2,2]	[3,0]	-1	hSpCas9	positive selection	3080273
43597827	43597850		+	24336571	A375	resistance to PLX after 7 days	ACTGGTTTTCAGTGTTCAGCTGG	POLH	ENSG00000170734	-0.050962822838796884	[9,8]	[8,7]	-1	hSpCas9	positive selection	3136702
43583102	43583125		+	24336571	A375	resistance to PLX after 7 days	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.23224418676180492	[8,10]	[11,11]	6	hSpCas9	positive selection	3136703
43597777	43597800		-	24336571	A375	resistance to PLX after 7 days	CTCCACAATCACTGCTCCCACGG	POLH	ENSG00000170734	-0.13500804586273882	[15,13]	[12,13]	-4	hSpCas9	positive selection	3136704
43583079	43583102		+	24336571	A375	resistance to PLX after 7 days	GTTATGTCCAGATCTTCTACTGG	POLH	ENSG00000170734	0.44087798308206383	[4,7]	[6,9]	9	hSpCas9	positive selection	3136706
43597827	43597850		+	24336571	A375	resistance to PLX after 14 days	ACTGGTTTTCAGTGTTCAGCTGG	POLH	ENSG00000170734	-0.4855592233470529	[6,8]	[1,2]	-6	hSpCas9	positive selection	3194495
43583102	43583125		+	24336571	A375	resistance to PLX after 14 days	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.5919486762431243	[9,11]	[7,6]	5	hSpCas9	positive selection	3194496
43597777	43597800		-	24336571	A375	resistance to PLX after 14 days	CTCCACAATCACTGCTCCCACGG	POLH	ENSG00000170734	-0.3934535240538503	[14,16]	[4,5]	-5	hSpCas9	positive selection	3194497
43583079	43583102		+	24336571	A375	resistance to PLX after 14 days	GTTATGTCCAGATCTTCTACTGG	POLH	ENSG00000170734	0.6240348186202019	[3,4]	[1,2]	5	hSpCas9	positive selection	3194499
43597827	43597850		+	24336571	A375	viability after 7 days	ACTGGTTTTCAGTGTTCAGCTGG	POLH	ENSG00000170734	-0.2365566624042489	[10]	[9,8]	-3	hSpCas9	negative selection	3252288
43583102	43583125		+	24336571	A375	viability after 7 days	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.032681862353889035	[10]	[8,10]	0	hSpCas9	negative selection	3252289
43597777	43597800		-	24336571	A375	viability after 7 days	CTCCACAATCACTGCTCCCACGG	POLH	ENSG00000170734	-0.35804101484505857	[19]	[15,13]	-5	hSpCas9	negative selection	3252290
43583079	43583102		+	24336571	A375	viability after 7 days	GTTATGTCCAGATCTTCTACTGG	POLH	ENSG00000170734	-0.5591417921948648	[9]	[4,7]	-7	hSpCas9	negative selection	3252292
43597827	43597850		+	24336571	A375	viability after 14 days	ACTGGTTTTCAGTGTTCAGCTGG	POLH	ENSG00000170734	-0.3355367404293571	[10]	[6,8]	-4	hSpCas9	negative selection	3310081
43583102	43583125		+	24336571	A375	viability after 14 days	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.07534310249138015	[10]	[9,11]	1	hSpCas9	negative selection	3310082
43597777	43597800		-	24336571	A375	viability after 14 days	CTCCACAATCACTGCTCCCACGG	POLH	ENSG00000170734	-0.22712196290174735	[19]	[14,16]	-3	hSpCas9	negative selection	3310083
43583079	43583102		+	24336571	A375	viability after 14 days	GTTATGTCCAGATCTTCTACTGG	POLH	ENSG00000170734	-1.0260158909342332	[9]	[3,4]	-8	hSpCas9	negative selection	3310085
43601004	43601027	6	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.9174762085612103	[80,80]	[0,0]	4	hSpCas9	positive selection	3386671
43597801	43597824	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	0.8143827155971068	[86,86]	[0,0]	4	hSpCas9	positive selection	3386672
43601017	43601040	6	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.9714924790500457	[299,299]	[0,0]	-6	hSpCas9	positive selection	3386673
43603892	43603915	6	-	26780180	HT29	viability (Avana library 4 designs)	CTAGCTTTCCTCCAAGACTACGG	POLH	ENSG00000170734	0.511464226050609	[]	[]	2	hSpCas9	negative selection	3450521
43601028	43601051	6	+	26780180	HT29	viability (Avana library 4 designs)	GCCAAACCCTGGTTTCACATGGG	POLH	ENSG00000170734	0.352819757802727	[]	[]	1	hSpCas9	negative selection	3450522
43603894	43603917	6	+	26780180	HT29	viability (Avana library 4 designs)	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	1.74596386164039	[]	[]	6	hSpCas9	negative selection	3450523
43587446	43587469	6	+	26780180	HT29	viability (Avana library 4 designs)	GTTGCCCCAAGGCCCTACAACGG	POLH	ENSG00000170734	0.35759313180592	[]	[]	1	hSpCas9	negative selection	3450524
43603892	43603915	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTAGCTTTCCTCCAAGACTACGG	POLH	ENSG00000170734	0.281701542461809	[]	[]	0	hSpCas9	negative selection	3545807
43587446	43587469	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGCCCCAAGGCCCTACAACGG	POLH	ENSG00000170734	3.08451619934681	[]	[]	5	hSpCas9	negative selection	3545808
43601028	43601051	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCAAACCCTGGTTTCACATGGG	POLH	ENSG00000170734	2.00254178195253	[]	[]	3	hSpCas9	negative selection	3545809
43603894	43603917	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	0.0199891174762953	[]	[]	0	hSpCas9	negative selection	3545810
43604667	43604690	6	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGGCAACTACCCAAAACCATTGG	POLH	ENSG00000170734	-2.70437545016305	[]	[]	-3	hSpCas9	negative selection	3545811
43583118	43583141	6	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGGTGAGGTTAGCTTTCCCACGG	POLH	ENSG00000170734	-1.88517575791244	[]	[]	-2	hSpCas9	negative selection	3545812
43603892	43603915	6	-	26780180	A375	viability (Avana lentiGuide)	CTAGCTTTCCTCCAAGACTACGG	POLH	ENSG00000170734	3.88617752530328	[]	[]	4	hSpCas9	negative selection	3654466
43587446	43587469	6	+	26780180	A375	viability (Avana lentiGuide)	GTTGCCCCAAGGCCCTACAACGG	POLH	ENSG00000170734	5.78871138790753	[]	[]	5	hSpCas9	negative selection	3654467
43601028	43601051	6	+	26780180	A375	viability (Avana lentiGuide)	GCCAAACCCTGGTTTCACATGGG	POLH	ENSG00000170734	-2.41040485705117	[]	[]	-4	hSpCas9	negative selection	3654468
43603894	43603917	6	+	26780180	A375	viability (Avana lentiGuide)	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	2.05495970558801	[]	[]	2	hSpCas9	negative selection	3654469
43604667	43604690	6	+	26780180	A375	viability (Avana lentiGuide)	AGGCAACTACCCAAAACCATTGG	POLH	ENSG00000170734	2.46991699770572	[]	[]	2	hSpCas9	negative selection	3654470
43583118	43583141	6	-	26780180	A375	viability (Avana lentiGuide)	TGGTGAGGTTAGCTTTCCCACGG	POLH	ENSG00000170734	20.7283800363787	[]	[]	8	hSpCas9	negative selection	3654471
43603892	43603915	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAGCTTTCCTCCAAGACTACGG	POLH	ENSG00000170734	-0.4065637462173711	[5]	[4,2]	-6	hSpCas9	positive selection	3763125
43587446	43587469	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGCCCCAAGGCCCTACAACGG	POLH	ENSG00000170734	-0.03332777409411908	[4]	[4,3]	0	hSpCas9	positive selection	3763126
43601028	43601051	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCAAACCCTGGTTTCACATGGG	POLH	ENSG00000170734	0.0326042505439139	[5]	[5,4]	0	hSpCas9	positive selection	3763127
43603894	43603917	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	0.0405536501371086	[5]	[5,5]	1	hSpCas9	positive selection	3763128
43604667	43604690	6	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGCAACTACCCAAAACCATTGG	POLH	ENSG00000170734	0.24305327827608034	[4]	[4,4]	7	hSpCas9	positive selection	3763129
43583118	43583141	6	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGTGAGGTTAGCTTTCCCACGG	POLH	ENSG00000170734	-0.1737369503209658	[5]	[5,4]	-3	hSpCas9	positive selection	3763130
43603892	43603915	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAGCTTTCCTCCAAGACTACGG	POLH	ENSG00000170734	0.17236877205213175	[5]	[5,4]	4	hSpCas9	positive selection	3871732
43587446	43587469	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGCCCCAAGGCCCTACAACGG	POLH	ENSG00000170734	-0.38759409601068084	[4]	[1,3]	-5	hSpCas9	positive selection	3871733
43601028	43601051	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCAAACCCTGGTTTCACATGGG	POLH	ENSG00000170734	-0.04739485538538685	[6]	[4,5]	0	hSpCas9	positive selection	3871734
43603894	43603917	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	0.09621751425784633	[5]	[5,5]	2	hSpCas9	positive selection	3871735
43604667	43604690	6	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGCAACTACCCAAAACCATTGG	POLH	ENSG00000170734	-0.18657401146036673	[5]	[3,3]	-3	hSpCas9	positive selection	3871736
43583118	43583141	6	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGTGAGGTTAGCTTTCCCACGG	POLH	ENSG00000170734	-0.6306941411752949	[6]	[3,2]	-7	hSpCas9	positive selection	3871737
43597801	43597824	6	+	26780180	A375	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	1.39024308197633	[]	[]	7	hSpCas9	negative selection	3982562
43583020	43583043	6	+	26780180	A375	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.204497016772906	[]	[]	0	hSpCas9	negative selection	3982563
43601017	43601040	6	+	26780180	A375	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	1.77680093638001	[]	[]	9	hSpCas9	negative selection	3982564
43583102	43583125	6	+	26780180	A375	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	1.8732046478548	[]	[]	9	hSpCas9	negative selection	3982565
43601004	43601027	6	-	26780180	A375	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	1.30716681758365	[]	[]	7	hSpCas9	negative selection	3982566
43597692	43597715	6	+	26780180	A375	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.866149640849946	[]	[]	3	hSpCas9	negative selection	3982567
43597801	43597824	6	+	26780180	HT29	viability (GeCKOv2 library)	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	1.59531165453532	[]	[]	8	hSpCas9	negative selection	4090528
43583020	43583043	6	+	26780180	HT29	viability (GeCKOv2 library)	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.335594161639373	[]	[]	0	hSpCas9	negative selection	4090529
43601017	43601040	6	+	26780180	HT29	viability (GeCKOv2 library)	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	1.26157454703788	[]	[]	6	hSpCas9	negative selection	4090530
43583102	43583125	6	+	26780180	HT29	viability (GeCKOv2 library)	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	1.54913035128255	[]	[]	7	hSpCas9	negative selection	4090531
43601004	43601027	6	-	26780180	HT29	viability (GeCKOv2 library)	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	1.24418562816856	[]	[]	6	hSpCas9	negative selection	4090532
43597692	43597715	6	+	26780180	HT29	viability (GeCKOv2 library)	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	1.22010768192671	[]	[]	6	hSpCas9	negative selection	4090533
43597827	43597850	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTGGTTTTCAGTGTTCAGCTGG	POLH	ENSG00000170734	-0.617682013109311	[3]	[1,0]	-9	hSpCas9	positive selection	4161752
43583102	43583125	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.1909685080774044	[3]	[1,2]	5	hSpCas9	positive selection	4161753
43597777	43597800	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCCACAATCACTGCTCCCACGG	POLH	ENSG00000170734	-0.16273797288045688	[4]	[2,2]	-4	hSpCas9	positive selection	4161754
43583079	43583102	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTATGTCCAGATCTTCTACTGG	POLH	ENSG00000170734	-0.34959295073379487	[3]	[1,1]	-7	hSpCas9	positive selection	4161756
43597827	43597850	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTGGTTTTCAGTGTTCAGCTGG	POLH	ENSG00000170734	0.5834026403168935	[1]	[0,0,1,0]	4	hSpCas9	positive selection	4225774
43583102	43583125	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.7410591011647139	[3]	[0,0,2,3]	5	hSpCas9	positive selection	4225775
43597777	43597800	6	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCCACAATCACTGCTCCCACGG	POLH	ENSG00000170734	0.9824316916513032	[4]	[4,3,2,3]	7	hSpCas9	positive selection	4225776
43583079	43583102	6	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTATGTCCAGATCTTCTACTGG	POLH	ENSG00000170734	0.43586468480606166	[2]	[1,0,5,0]	3	hSpCas9	positive selection	4225778
43583102	43583125	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.1266990799858922	[3]	[3,2]	2	hSpCas9	positive selection	4291177
43597692	43597715	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.4082330621465483	[3]	[3,3]	8	hSpCas9	positive selection	4291178
43583020	43583043	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.8571340858631891	[3]	[3,6]	9	hSpCas9	positive selection	4291179
43601004	43601027	6	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.33789463644907475	[1]	[0,1]	-6	hSpCas9	positive selection	4355426
43597801	43597824	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	0.2802115279697898	[2]	[2,1]	5	hSpCas9	positive selection	4355427
43601017	43601040	6	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.45496218467655625	[3]	[2,0]	-7	hSpCas9	positive selection	4355428
43582428	43582450	6	+	27760321	OCIAML3	viability	GTACAGTACAAATCATGGAAGG	POLH	ENSG00000170734	0.6917754013366846	[106,96]	[113,147]	7	hSpCas9	negative selection	4429185
43583103	43583125	6	+	27760321	OCIAML3	viability	ACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.4068612065720568	[673,559]	[341,388]	-4	hSpCas9	negative selection	4429186
43587405	43587427	6	-	27760321	OCIAML3	viability	GCAACAAGTCTGCCGAGATAGG	POLH	ENSG00000170734	0.09845713556493424	[594,468]	[429,458]	1	hSpCas9	negative selection	4429187
43603918	43603940	6	-	27760321	OCIAML3	viability	CCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.36875635451635913	[342,235]	[118,243]	-4	hSpCas9	negative selection	4429188
43604629	43604651	6	-	27760321	OCIAML3	viability	TGTTCAATCCCTCGGCACATGG	POLH	ENSG00000170734	0.29205947612145255	[992,873]	[632,1229]	3	hSpCas9	negative selection	4429189
43582428	43582450	6	+	27760321	OCIAML2	viability	GTACAGTACAAATCATGGAAGG	POLH	ENSG00000170734	-0.35089205757543107	[106,96]	[52,79]	-4	hSpCas9	negative selection	4512648
43583103	43583125	6	+	27760321	OCIAML2	viability	ACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.18067923563672328	[673,559]	[416,755]	2	hSpCas9	negative selection	4512649
43587405	43587427	6	-	27760321	OCIAML2	viability	GCAACAAGTCTGCCGAGATAGG	POLH	ENSG00000170734	0.03530417448431833	[594,468]	[347,556]	0	hSpCas9	negative selection	4512650
43603918	43603940	6	-	27760321	OCIAML2	viability	CCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.24140794123216125	[342,235]	[168,230]	-3	hSpCas9	negative selection	4512651
43604629	43604651	6	-	27760321	OCIAML2	viability	TGTTCAATCCCTCGGCACATGG	POLH	ENSG00000170734	-0.00340074188464623	[992,873]	[700,818]	0	hSpCas9	negative selection	4512652
43582428	43582450	6	+	27760321	MV411	viability	GTACAGTACAAATCATGGAAGG	POLH	ENSG00000170734	1.3030577339392995	[106,96]	[123,228]	8	hSpCas9	negative selection	4596111
43583103	43583125	6	+	27760321	MV411	viability	ACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.041350266842674344	[673,559]	[96,839]	0	hSpCas9	negative selection	4596112
43587405	43587427	6	-	27760321	MV411	viability	GCAACAAGTCTGCCGAGATAGG	POLH	ENSG00000170734	1.182235108183214	[594,468]	[962,533]	8	hSpCas9	negative selection	4596113
43603918	43603940	6	-	27760321	MV411	viability	CCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.42025040729603147	[342,235]	[258,242]	3	hSpCas9	negative selection	4596114
43604629	43604651	6	-	27760321	MV411	viability	TGTTCAATCCCTCGGCACATGG	POLH	ENSG00000170734	0.3203062096684828	[992,873]	[837,661]	2	hSpCas9	negative selection	4596115
43582428	43582450	6	+	27760321	HL60	viability	GTACAGTACAAATCATGGAAGG	POLH	ENSG00000170734	-0.29395169875214666	[106,96]	[64,70]	-3	hSpCas9	negative selection	4679574
43583103	43583125	6	+	27760321	HL60	viability	ACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.3059760169048379	[673,559]	[517,728]	4	hSpCas9	negative selection	4679575
43587405	43587427	6	-	27760321	HL60	viability	GCAACAAGTCTGCCGAGATAGG	POLH	ENSG00000170734	-0.4941485568589412	[594,468]	[208,409]	-5	hSpCas9	negative selection	4679576
43603918	43603940	6	-	27760321	HL60	viability	CCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.25741328856674683	[342,235]	[161,230]	-3	hSpCas9	negative selection	4679577
43604629	43604651	6	-	27760321	HL60	viability	TGTTCAATCCCTCGGCACATGG	POLH	ENSG00000170734	-0.09853543790659647	[992,873]	[588,839]	-1	hSpCas9	negative selection	4679578
43582428	43582450	6	+	27760321	HT1080	viability	GTACAGTACAAATCATGGAAGG	POLH	ENSG00000170734	-0.6656602555538584	[96,75]	[15,27]	-3	hSpCas9	negative selection	4763037
43583103	43583125	6	+	27760321	HT1080	viability	ACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.24129128592781451	[559,436]	[302,159]	1	hSpCas9	negative selection	4763038
43587405	43587427	6	-	27760321	HT1080	viability	GCAACAAGTCTGCCGAGATAGG	POLH	ENSG00000170734	2.017686875457109	[468,365]	[925,396]	9	hSpCas9	negative selection	4763039
43603918	43603940	6	-	27760321	HT1080	viability	CCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.5400678836042855	[235,183]	[134,106]	3	hSpCas9	negative selection	4763040
43604629	43604651	6	-	27760321	HT1080	viability	TGTTCAATCCCTCGGCACATGG	POLH	ENSG00000170734	0.0649721804102279	[873,681]	[180,480]	0	hSpCas9	negative selection	4763041
43582428	43582450	6	+	27760321	HT29	viability after 7 days	GTACAGTACAAATCATGGAAGG	POLH	ENSG00000170734	-0.1985058133546933	[96,75]	[98,63,126]	-3	hSpCas9	negative selection	4846500
43583103	43583125	6	+	27760321	HT29	viability after 7 days	ACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.1416208553231295	[559,436]	[859,533,393]	-2	hSpCas9	negative selection	4846501
43587405	43587427	6	-	27760321	HT29	viability after 7 days	GCAACAAGTCTGCCGAGATAGG	POLH	ENSG00000170734	0.19658204259733741	[468,365]	[800,739,338]	3	hSpCas9	negative selection	4846502
43603918	43603940	6	-	27760321	HT29	viability after 7 days	CCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.29308740792429844	[235,183]	[198,184,271]	-4	hSpCas9	negative selection	4846503
43604629	43604651	6	-	27760321	HT29	viability after 7 days	TGTTCAATCCCTCGGCACATGG	POLH	ENSG00000170734	0.044257269117278675	[873,681]	[1386,1026,738]	0	hSpCas9	negative selection	4846504
43582428	43582450	6	+	27760321	HT29	viability after 25 days	GTACAGTACAAATCATGGAAGG	POLH	ENSG00000170734	-0.8876707144043623	[96,75]	[1,94,67]	-6	hSpCas9	negative selection	4929963
43583103	43583125	6	+	27760321	HT29	viability after 25 days	ACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.2992521158385936	[559,436]	[829,707,538]	3	hSpCas9	negative selection	4929964
43587405	43587427	6	-	27760321	HT29	viability after 25 days	GCAACAAGTCTGCCGAGATAGG	POLH	ENSG00000170734	0.6938303945344523	[468,365]	[726,757,838]	7	hSpCas9	negative selection	4929965
43603918	43603940	6	-	27760321	HT29	viability after 25 days	CCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.7817067196689345	[235,183]	[407,436,389]	8	hSpCas9	negative selection	4929966
43604629	43604651	6	-	27760321	HT29	viability after 25 days	TGTTCAATCCCTCGGCACATGG	POLH	ENSG00000170734	-0.15297090915439282	[873,681]	[824,772,797]	-1	hSpCas9	negative selection	4929967
43582428	43582450	6	+	27760321	HT29	viability after 22 days	GTACAGTACAAATCATGGAAGG	POLH	ENSG00000170734	0.1769188775583177	[96,75]	[25,156,158]	1	hSpCas9	negative selection	5013426
43583103	43583125	6	+	27760321	HT29	viability after 22 days	ACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.17053138899050918	[559,436]	[621,829,492]	1	hSpCas9	negative selection	5013427
43587405	43587427	6	-	27760321	HT29	viability after 22 days	GCAACAAGTCTGCCGAGATAGG	POLH	ENSG00000170734	0.395557993822522	[468,365]	[595,645,663]	4	hSpCas9	negative selection	5013428
43603918	43603940	6	-	27760321	HT29	viability after 22 days	CCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.34372022535905683	[235,183]	[257,309,357]	3	hSpCas9	negative selection	5013429
43604629	43604651	6	-	27760321	HT29	viability after 22 days	TGTTCAATCCCTCGGCACATGG	POLH	ENSG00000170734	-0.12731896879742444	[873,681]	[799,938,730]	-1	hSpCas9	negative selection	5013430
43582428	43582450	6	+	27760321	HT29	viability after 19 days	GTACAGTACAAATCATGGAAGG	POLH	ENSG00000170734	0.1709894179585354	[96,75]	[41,176,107]	1	hSpCas9	negative selection	5096889
43583103	43583125	6	+	27760321	HT29	viability after 19 days	ACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.09787126280703845	[559,436]	[776,447,621]	0	hSpCas9	negative selection	5096890
43587405	43587427	6	-	27760321	HT29	viability after 19 days	GCAACAAGTCTGCCGAGATAGG	POLH	ENSG00000170734	0.8048985728002802	[468,365]	[774,919,801]	8	hSpCas9	negative selection	5096891
43603918	43603940	6	-	27760321	HT29	viability after 19 days	CCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.4547175972767561	[235,183]	[353,338,297]	4	hSpCas9	negative selection	5096892
43604629	43604651	6	-	27760321	HT29	viability after 19 days	TGTTCAATCCCTCGGCACATGG	POLH	ENSG00000170734	0.08660949545273078	[873,681]	[802,642,1356]	0	hSpCas9	negative selection	5096893
43582428	43582450	6	+	27760321	HT29	viability after 16 days	GTACAGTACAAATCATGGAAGG	POLH	ENSG00000170734	-1.4990915094745358	[96,75]	[41,51,8]	-8	hSpCas9	negative selection	5180352
43583103	43583125	6	+	27760321	HT29	viability after 16 days	ACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.0005329857982683261	[559,436]	[593,476,606]	0	hSpCas9	negative selection	5180353
43587405	43587427	6	-	27760321	HT29	viability after 16 days	GCAACAAGTCTGCCGAGATAGG	POLH	ENSG00000170734	0.2786392808091513	[468,365]	[670,589,447]	3	hSpCas9	negative selection	5180354
43603918	43603940	6	-	27760321	HT29	viability after 16 days	CCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.6069130918858064	[235,183]	[221,262,577]	7	hSpCas9	negative selection	5180355
43604629	43604651	6	-	27760321	HT29	viability after 16 days	TGTTCAATCCCTCGGCACATGG	POLH	ENSG00000170734	0.14118037661953786	[873,681]	[745,781,1335]	1	hSpCas9	negative selection	5180356
43582428	43582450	6	+	27760321	HT29	viability after 13 days	GTACAGTACAAATCATGGAAGG	POLH	ENSG00000170734	-0.15145924395010546	[96,75]	[56,171,44]	-2	hSpCas9	negative selection	5263815
43583103	43583125	6	+	27760321	HT29	viability after 13 days	ACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.22933667204896863	[559,436]	[833,736,474]	3	hSpCas9	negative selection	5263816
43587405	43587427	6	-	27760321	HT29	viability after 13 days	GCAACAAGTCTGCCGAGATAGG	POLH	ENSG00000170734	0.14879298220919757	[468,365]	[471,551,583]	1	hSpCas9	negative selection	5263817
43603918	43603940	6	-	27760321	HT29	viability after 13 days	CCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.4276248929074284	[235,183]	[516,129,334]	5	hSpCas9	negative selection	5263818
43604629	43604651	6	-	27760321	HT29	viability after 13 days	TGTTCAATCCCTCGGCACATGG	POLH	ENSG00000170734	-0.14917809216520406	[873,681]	[1053,590,796]	-2	hSpCas9	negative selection	5263819
43582428	43582450	6	+	27760321	HT29	viability after 10 days	GTACAGTACAAATCATGGAAGG	POLH	ENSG00000170734	0.3060698322983153	[96,75]	[219,121,59]	4	hSpCas9	negative selection	5347278
43583103	43583125	6	+	27760321	HT29	viability after 10 days	ACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	0.36357337541715	[559,436]	[620,976,808]	5	hSpCas9	negative selection	5347279
43587405	43587427	6	-	27760321	HT29	viability after 10 days	GCAACAAGTCTGCCGAGATAGG	POLH	ENSG00000170734	0.7521245173864164	[468,365]	[747,680,1191]	8	hSpCas9	negative selection	5347280
43603918	43603940	6	-	27760321	HT29	viability after 10 days	CCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.0002457914116783533	[235,183]	[240,218,323]	0	hSpCas9	negative selection	5347281
43604629	43604651	6	-	27760321	HT29	viability after 10 days	TGTTCAATCCCTCGGCACATGG	POLH	ENSG00000170734	0.17878224160321832	[873,681]	[1093,1234,975]	2	hSpCas9	negative selection	5347282
43582428	43582450	6	+	27760321	MOLM13	viability	GTACAGTACAAATCATGGAAGG	POLH	ENSG00000170734	-5.222541348048939	[106,96]	[0,1]	-9	hSpCas9	negative selection	5430741
43583103	43583125	6	+	27760321	MOLM13	viability	ACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.15660941134837042	[673,559]	[324,298]	-1	hSpCas9	negative selection	5430742
43587405	43587427	6	-	27760321	MOLM13	viability	GCAACAAGTCTGCCGAGATAGG	POLH	ENSG00000170734	0.29933451012085616	[594,468]	[494,257]	2	hSpCas9	negative selection	5430743
43603918	43603940	6	-	27760321	MOLM13	viability	CCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	1.3833526001763519	[342,235]	[581,283]	8	hSpCas9	negative selection	5430744
43604629	43604651	6	-	27760321	MOLM13	viability	TGTTCAATCCCTCGGCACATGG	POLH	ENSG00000170734	0.6708839227186802	[992,873]	[636,1006]	4	hSpCas9	negative selection	5430745
43576145	43576168	6	+	27661255	K562	viability	GCGTCAACGGCCCTTCGCAGCGG	POLH	ENSG00000170734	0.24386679594904062	[609,657]	[586,608]	7	dCas9-KRAB	negative selection	5503028
43576181	43576204	6	-	27661255	K562	viability	GCAATGCAGCCGCCAGACTGAGG	POLH	ENSG00000170734	-0.1166157692695432	[1236,1488]	[1022,981]	-4	dCas9-KRAB	negative selection	5503029
43576267	43576290	6	-	27661255	K562	viability	GACGACGGAGAAACCGAGAAGGG	POLH	ENSG00000170734	0.11275019772217443	[1425,1375]	[1347,1093]	4	dCas9-KRAB	negative selection	5503030
43583102	43583125	6	+	27260156	BXPC3	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.17417438295677112	[821]	[676,530,891,995]	-4	hSpCas9	negative selection	5563637
43597692	43597715	6	+	27260156	BXPC3	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.11719543793502518	[756]	[687,804,987,986]	2	hSpCas9	negative selection	5563638
43583020	43583043	6	+	27260156	BXPC3	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.2217889763673453	[724]	[610,989,780,1209]	5	hSpCas9	negative selection	5563639
43601004	43601027	6	-	27260156	BXPC3	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.13751179262179836	[175]	[201,175,199,235]	3	hSpCas9	negative selection	5627886
43597801	43597824	6	+	27260156	BXPC3	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.20571365638177552	[280]	[223,245,221,338]	-5	hSpCas9	negative selection	5627887
43601017	43601040	6	+	27260156	BXPC3	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.0817006564636692	[713]	[654,694,685,797]	-2	hSpCas9	negative selection	5627888
43583102	43583125	6	+	27260156	A673	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.33393065831079655	[821]	[903,638,661,953]	-7	hSpCas9	negative selection	5684888
43597692	43597715	6	+	27260156	A673	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.1437117884423159	[756]	[915,789,750,845]	-4	hSpCas9	negative selection	5684889
43583020	43583043	6	+	27260156	A673	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.1712596859220431	[724]	[1131,842,1000,962]	4	hSpCas9	negative selection	5684890
43601004	43601027	6	-	27260156	A673	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.08105741495636254	[175]	[208,164,174,254]	-2	hSpCas9	negative selection	5749137
43597801	43597824	6	+	27260156	A673	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.007110674763189606	[280]	[303,317,361,355]	0	hSpCas9	negative selection	5749138
43601017	43601040	6	+	27260156	A673	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.15441367763858838	[713]	[847,816,586,840]	-4	hSpCas9	negative selection	5749139
43583102	43583125	6	+	27260156	A375	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.21284247942755563	[821]	[978,1306,623,506]	-3	hSpCas9	negative selection	5806139
43597692	43597715	6	+	27260156	A375	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.3303324606492902	[756]	[996,1383,1158,957]	5	hSpCas9	negative selection	5806140
43583020	43583043	6	+	27260156	A375	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.43578336368246284	[724]	[913,1279,1132,1253]	6	hSpCas9	negative selection	5806141
43601004	43601027	6	-	27260156	A375	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.2794225770002956	[175]	[227,327,305,156]	4	hSpCas9	negative selection	5870388
43597801	43597824	6	+	27260156	A375	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.09239838078544071	[280]	[208,515,184,343]	-1	hSpCas9	negative selection	5870389
43601017	43601040	6	+	27260156	A375	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.17744619954033508	[713]	[826,859,525,749]	-3	hSpCas9	negative selection	5870390
43583102	43583125	6	+	27260156	COLO741	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.23204411095426292	[821]	[891,733,1042]	-5	hSpCas9	negative selection	5927390
43597692	43597715	6	+	27260156	COLO741	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.052536095384196124	[756]	[1081,864,1061]	1	hSpCas9	negative selection	5927391
43583020	43583043	6	+	27260156	COLO741	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.18784217769622857	[724]	[1100,1095,975]	4	hSpCas9	negative selection	5927392
43601004	43601027	6	-	27260156	COLO741	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.16027051383906898	[175]	[168,277,156]	-3	hSpCas9	negative selection	5991639
43597801	43597824	6	+	27260156	COLO741	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.10631824243819488	[280]	[412,295,299]	-2	hSpCas9	negative selection	5991640
43601017	43601040	6	+	27260156	COLO741	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	0.07227136109675181	[713]	[943,1053,881]	1	hSpCas9	negative selection	5991641
43583102	43583125	6	+	27260156	CAL120	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.4947018405270382	[821]	[770,668,743]	-6	hSpCas9	negative selection	6048641
43597692	43597715	6	+	27260156	CAL120	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.24851486452966565	[756]	[1344,1218,831]	4	hSpCas9	negative selection	6048642
43583020	43583043	6	+	27260156	CAL120	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.3506590471199422	[724]	[1289,1156,1026]	5	hSpCas9	negative selection	6048643
43601004	43601027	6	-	27260156	CAL120	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.37423507960400726	[175]	[195,150,163]	-5	hSpCas9	negative selection	6112890
43597801	43597824	6	+	27260156	CAL120	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.006387866440077716	[280]	[372,271,401]	0	hSpCas9	negative selection	6112891
43601017	43601040	6	+	27260156	CAL120	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.5313379851329662	[713]	[563,691,580]	-6	hSpCas9	negative selection	6112892
43583102	43583125	6	+	27260156	CADOES1	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.48922642311706516	[821]	[538,830,346,458]	-7	hSpCas9	negative selection	6169892
43597692	43597715	6	+	27260156	CADOES1	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.24640878949383527	[756]	[762,788,922,866]	4	hSpCas9	negative selection	6169893
43583020	43583043	6	+	27260156	CADOES1	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.41456714858777866	[724]	[1003,761,763,1070]	7	hSpCas9	negative selection	6169894
43601004	43601027	6	-	27260156	CADOES1	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.3306740411515332	[175]	[126,111,115,166]	-5	hSpCas9	negative selection	6234141
43597801	43597824	6	+	27260156	CADOES1	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.08577269741738647	[280]	[230,230,226,297]	-1	hSpCas9	negative selection	6234142
43601017	43601040	6	+	27260156	CADOES1	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.41036904521490947	[713]	[593,515,425,460]	-6	hSpCas9	negative selection	6234143
43583102	43583125	6	+	27260156	EWS502	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.3827799831248102	[821]	[830,534,672,610]	-6	hSpCas9	negative selection	6291143
43597692	43597715	6	+	27260156	EWS502	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.08967466190234619	[756]	[947,460,700,898]	-2	hSpCas9	negative selection	6291144
43583020	43583043	6	+	27260156	EWS502	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.3219060842384147	[724]	[751,834,1052,1247]	5	hSpCas9	negative selection	6291145
43601004	43601027	6	-	27260156	EWS502	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.09698752713997627	[175]	[159,76,257,210]	-2	hSpCas9	negative selection	6355392
43597801	43597824	6	+	27260156	EWS502	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	0.011477775099205223	[280]	[303,251,279,368]	0	hSpCas9	negative selection	6355393
43601017	43601040	6	+	27260156	EWS502	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	0.054186648794496195	[713]	[614,828,617,1115]	0	hSpCas9	negative selection	6355394
43583102	43583125	6	+	27260156	EW8	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.5052013834649325	[821]	[537,510,391,455]	-7	hSpCas9	negative selection	6412394
43597692	43597715	6	+	27260156	EW8	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.14159097738981807	[756]	[537,785,439,477]	-3	hSpCas9	negative selection	6412395
43583020	43583043	6	+	27260156	EW8	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.1424413564646957	[724]	[716,560,529,810]	2	hSpCas9	negative selection	6412396
43601004	43601027	6	-	27260156	EW8	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.0365120389922613	[175]	[205,143,148,91]	0	hSpCas9	negative selection	6476643
43597801	43597824	6	+	27260156	EW8	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.3597141530291944	[280]	[220,216,132,150]	-6	hSpCas9	negative selection	6476644
43601017	43601040	6	+	27260156	EW8	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.18990890738246785	[713]	[759,463,385,465]	-4	hSpCas9	negative selection	6476645
43583102	43583125	6	+	27260156	CORL105	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.004432790591202274	[821]	[856,843,1284,900]	0	hSpCas9	negative selection	6533645
43597692	43597715	6	+	27260156	CORL105	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.22024493266514678	[756]	[1131,1039,1170,811]	4	hSpCas9	negative selection	6533646
43583020	43583043	6	+	27260156	CORL105	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.4551330556655919	[724]	[1065,1172,1457,999]	8	hSpCas9	negative selection	6533647
43601004	43601027	6	-	27260156	CORL105	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.05475481847481989	[175]	[167,197,379,134]	1	hSpCas9	negative selection	6597894
43597801	43597824	6	+	27260156	CORL105	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.16032926525717084	[280]	[271,300,316,289]	-3	hSpCas9	negative selection	6597895
43601017	43601040	6	+	27260156	CORL105	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.1251570193104758	[713]	[743,822,749,743]	-2	hSpCas9	negative selection	6597896
43583102	43583125	6	+	27260156	HS294T	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.3757319529200227	[821]	[176,267,323,209]	-5	hSpCas9	negative selection	6654896
43597692	43597715	6	+	27260156	HS294T	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.13844560528741723	[756]	[293,326,412,242]	2	hSpCas9	negative selection	6654897
43583020	43583043	6	+	27260156	HS294T	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.9510529471641114	[724]	[367,819,449,533]	9	hSpCas9	negative selection	6654898
43601004	43601027	6	-	27260156	HS294T	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.704913953085025	[175]	[25,58,39,42]	-7	hSpCas9	negative selection	6719145
43597801	43597824	6	+	27260156	HS294T	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	0.46106552805149037	[280]	[73,154,75,329]	6	hSpCas9	negative selection	6719146
43601017	43601040	6	+	27260156	HS294T	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.25862958649694173	[713]	[281,171,220,246]	-4	hSpCas9	negative selection	6719147
43583102	43583125	6	+	27260156	HCC44	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.39822844923803247	[821]	[544,855,816,584]	-6	hSpCas9	negative selection	6776147
43597692	43597715	6	+	27260156	HCC44	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.18108395914728204	[756]	[718,647,992,708]	-3	hSpCas9	negative selection	6776148
43583020	43583043	6	+	27260156	HCC44	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.28576099161312085	[724]	[1119,880,1172,877]	4	hSpCas9	negative selection	6776149
43601004	43601027	6	-	27260156	HCC44	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.20317227563035622	[175]	[135,227,270,276]	3	hSpCas9	negative selection	6840396
43597801	43597824	6	+	27260156	HCC44	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.8016170366280994	[280]	[147,111,301,192]	-8	hSpCas9	negative selection	6840397
43601017	43601040	6	+	27260156	HCC44	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.07760938367743331	[713]	[555,729,1089,721]	-1	hSpCas9	negative selection	6840398
43583102	43583125	6	+	27260156	G402	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.41522394653028266	[821]	[858,571,1088,502]	-5	hSpCas9	negative selection	6897398
43597692	43597715	6	+	27260156	G402	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.10987765520072945	[756]	[961,493,1467,507]	-1	hSpCas9	negative selection	6897399
43583020	43583043	6	+	27260156	G402	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.5206111926731822	[724]	[1236,1606,964,1276]	6	hSpCas9	negative selection	6897400
43601004	43601027	6	-	27260156	G402	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.07278720274778916	[175]	[104,250,291,237]	0	hSpCas9	negative selection	6961647
43597801	43597824	6	+	27260156	G402	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.47513357606645246	[280]	[212,287,293,190]	-5	hSpCas9	negative selection	6961648
43601017	43601040	6	+	27260156	G402	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.5456303893988458	[713]	[581,732,501,574]	-6	hSpCas9	negative selection	6961649
43583102	43583125	6	+	27260156	L33	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.2898786462711326	[821]	[583,285,371,815]	-6	hSpCas9	negative selection	7018649
43597692	43597715	6	+	27260156	L33	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.28718417105448824	[756]	[851,378,574,1003]	6	hSpCas9	negative selection	7018650
43583020	43583043	6	+	27260156	L33	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.10060744832771962	[724]	[794,278,492,847]	2	hSpCas9	negative selection	7018651
43601004	43601027	6	-	27260156	L33	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.24263876043218957	[175]	[132,57,116,134]	-5	hSpCas9	negative selection	7082898
43597801	43597824	6	+	27260156	L33	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.21265918459303523	[280]	[268,90,113,295]	-5	hSpCas9	negative selection	7082899
43601017	43601040	6	+	27260156	L33	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.1549200130133112	[713]	[619,277,448,553]	-4	hSpCas9	negative selection	7082900
43583102	43583125	6	+	27260156	K562	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.9394234510887317	[821]	[440,420,416,261]	-8	hSpCas9	negative selection	7139900
43597692	43597715	6	+	27260156	K562	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.1510020196540417	[756]	[986,671,326,480]	-2	hSpCas9	negative selection	7139901
43583020	43583043	6	+	27260156	K562	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	1.242929617816561	[724]	[1245,2274,959,1609]	9	hSpCas9	negative selection	7139902
43601004	43601027	6	-	27260156	K562	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.5790393434267125	[175]	[98,120,157,46]	-6	hSpCas9	negative selection	7204149
43597801	43597824	6	+	27260156	K562	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.8990761622625999	[280]	[145,101,60,214]	-7	hSpCas9	negative selection	7204150
43601017	43601040	6	+	27260156	K562	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.8825268576407312	[713]	[336,424,242,368]	-7	hSpCas9	negative selection	7204151
43583102	43583125	6	+	27260156	HT29	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.26761067838695984	[821]	[669,850,847,922]	-5	hSpCas9	negative selection	7261151
43597692	43597715	6	+	27260156	HT29	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.15716555171773072	[756]	[971,912,892,567]	-3	hSpCas9	negative selection	7261152
43583020	43583043	6	+	27260156	HT29	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.23421662020560097	[724]	[1257,1098,1014,816]	4	hSpCas9	negative selection	7261153
43601004	43601027	6	-	27260156	HT29	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.1761283368564801	[175]	[266,198,224,268]	3	hSpCas9	negative selection	7325400
43597801	43597824	6	+	27260156	HT29	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.13588283820556235	[280]	[347,444,217,251]	-3	hSpCas9	negative selection	7325401
43601017	43601040	6	+	27260156	HT29	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.027407899882635922	[713]	[687,960,904,843]	0	hSpCas9	negative selection	7325402
43583102	43583125	6	+	27260156	MHHES1	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.4677288062486829	[821]	[783,712,662,548]	-7	hSpCas9	negative selection	7382402
43597692	43597715	6	+	27260156	MHHES1	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.1151708795807902	[756]	[992,1002,626,597]	-2	hSpCas9	negative selection	7382403
43583020	43583043	6	+	27260156	MHHES1	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.41822762452774853	[724]	[1036,1292,976,1053]	7	hSpCas9	negative selection	7382404
43601004	43601027	6	-	27260156	MHHES1	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.2664567955766437	[175]	[165,168,166,155]	-5	hSpCas9	negative selection	7446651
43597801	43597824	6	+	27260156	MHHES1	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.42996553761477296	[280]	[233,205,254,235]	-7	hSpCas9	negative selection	7446652
43601017	43601040	6	+	27260156	MHHES1	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.2922360870219933	[713]	[717,895,591,478]	-5	hSpCas9	negative selection	7446653
43583102	43583125	6	+	27260156	MEWO	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.19081512662738398	[821]	[737,584,710]	-4	hSpCas9	negative selection	7503653
43597692	43597715	6	+	27260156	MEWO	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.2161153176903473	[756]	[879,808,789]	5	hSpCas9	negative selection	7503654
43583020	43583043	6	+	27260156	MEWO	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.29342523871177095	[724]	[931,857,722]	6	hSpCas9	negative selection	7503655
43601004	43601027	6	-	27260156	MEWO	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.14247616010157982	[175]	[176,124,150]	-3	hSpCas9	negative selection	7567902
43597801	43597824	6	+	27260156	MEWO	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.04551855920961001	[280]	[210,183,360]	-1	hSpCas9	negative selection	7567903
43601017	43601040	6	+	27260156	MEWO	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	0.2227947164684625	[713]	[728,913,684]	5	hSpCas9	negative selection	7567904
43583102	43583125	6	+	27260156	LNCAPCLONEFGC	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.4003853879667647	[821]	[502,523,704,548]	-6	hSpCas9	negative selection	7624904
43597692	43597715	6	+	27260156	LNCAPCLONEFGC	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.1692089626622677	[756]	[616,880,895,703]	2	hSpCas9	negative selection	7624905
43583020	43583043	6	+	27260156	LNCAPCLONEFGC	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.43978759726590044	[724]	[774,1039,829,900]	7	hSpCas9	negative selection	7624906
43601004	43601027	6	-	27260156	LNCAPCLONEFGC	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.036391740801870576	[175]	[116,187,159,155]	0	hSpCas9	negative selection	7689153
43597801	43597824	6	+	27260156	LNCAPCLONEFGC	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	0.08909235970598928	[280]	[249,223,355,268]	1	hSpCas9	negative selection	7689154
43601017	43601040	6	+	27260156	LNCAPCLONEFGC	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.3020857811020466	[713]	[408,441,694,584]	-5	hSpCas9	negative selection	7689155
43583102	43583125	6	+	27260156	PANC0327	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.5717395633438735	[821]	[428,466,523,542]	-7	hSpCas9	negative selection	7746155
43597692	43597715	6	+	27260156	PANC0327	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.41122766407712574	[756]	[660,481,336,557]	-5	hSpCas9	negative selection	7746156
43583020	43583043	6	+	27260156	PANC0327	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.7706294669491573	[724]	[1755,964,684,1058]	9	hSpCas9	negative selection	7746157
43601004	43601027	6	-	27260156	PANC0327	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.06678514410574432	[175]	[39,177,206,217]	1	hSpCas9	negative selection	7810404
43597801	43597824	6	+	27260156	PANC0327	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.594356600104028	[280]	[140,275,141,85]	-7	hSpCas9	negative selection	7810405
43601017	43601040	6	+	27260156	PANC0327	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.5609038570039249	[713]	[499,315,403,519]	-7	hSpCas9	negative selection	7810406
43583102	43583125	6	+	27260156	NCIH2009	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.41159812842509563	[821]	[1093,770,770]	-5	hSpCas9	negative selection	7867406
43597692	43597715	6	+	27260156	NCIH2009	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.26429201979094213	[756]	[907,865,871]	-4	hSpCas9	negative selection	7867407
43583020	43583043	6	+	27260156	NCIH2009	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.6001662967168395	[724]	[1749,1386,1511]	8	hSpCas9	negative selection	7867408
43601004	43601027	6	-	27260156	NCIH2009	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.1813174401808395	[175]	[259,239,332]	2	hSpCas9	negative selection	7931655
43597801	43597824	6	+	27260156	NCIH2009	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.535466855868964	[280]	[334,150,340]	-6	hSpCas9	negative selection	7931656
43601017	43601040	6	+	27260156	NCIH2009	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.3234734889766132	[713]	[957,743,720]	-4	hSpCas9	negative selection	7931657
43583102	43583125	6	+	27260156	NCIH1373	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.44195503811815745	[821]	[792,368,702,238]	-4	hSpCas9	negative selection	7988657
43597692	43597715	6	+	27260156	NCIH1373	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.6603612156546298	[756]	[516,339,354,257]	-6	hSpCas9	negative selection	7988658
43583020	43583043	6	+	27260156	NCIH1373	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	1.203486220369164	[724]	[2838,1142,1750,520]	9	hSpCas9	negative selection	7988659
43601004	43601027	6	-	27260156	NCIH1373	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.4531224469061095	[175]	[294,129,113,14]	-4	hSpCas9	negative selection	8052906
43597801	43597824	6	+	27260156	NCIH1373	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.8963020313281641	[280]	[127,281,70,46]	-7	hSpCas9	negative selection	8052907
43601017	43601040	6	+	27260156	NCIH1373	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.4516109864262937	[713]	[896,258,208,287]	-4	hSpCas9	negative selection	8052908
43583102	43583125	6	+	27260156	PATU8902	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.9961428524984347	[821]	[354,780,390,847]	-7	hSpCas9	negative selection	8109908
43597692	43597715	6	+	27260156	PATU8902	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.5981484650783977	[756]	[700,1263,254,673]	-5	hSpCas9	negative selection	8109909
43583020	43583043	6	+	27260156	PATU8902	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.9260311123411664	[724]	[2540,2040,1090,2229]	8	hSpCas9	negative selection	8109910
43601004	43601027	6	-	27260156	PATU8902	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.3609096271264596	[175]	[257,155,239,80]	-4	hSpCas9	negative selection	8174157
43597801	43597824	6	+	27260156	PATU8902	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.49101307783592596	[280]	[256,119,369,348]	-5	hSpCas9	negative selection	8174158
43601017	43601040	6	+	27260156	PATU8902	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.8711667572595596	[713]	[693,541,406,562]	-7	hSpCas9	negative selection	8174159
43583102	43583125	6	+	27260156	PANC1	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.572425975715316	[821]	[370,496,458,556]	-7	hSpCas9	negative selection	8231159
43597692	43597715	6	+	27260156	PANC1	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.08536590280358469	[756]	[428,834,813,442]	-1	hSpCas9	negative selection	8231160
43583020	43583043	6	+	27260156	PANC1	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.498724407778947	[724]	[768,1009,1021,754]	7	hSpCas9	negative selection	8231161
43601004	43601027	6	-	27260156	PANC1	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.8977291028716539	[175]	[86,81,71,81]	-8	hSpCas9	negative selection	8295408
43597801	43597824	6	+	27260156	PANC1	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.26582935881234937	[280]	[201,209,192,196]	-4	hSpCas9	negative selection	8295409
43601017	43601040	6	+	27260156	PANC1	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.5399059182466854	[713]	[180,723,522,334]	-7	hSpCas9	negative selection	8295410
43583102	43583125	6	+	27260156	PANC0813	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.01922131909358804	[821]	[951,855,1083,919]	0	hSpCas9	negative selection	8352410
43597692	43597715	6	+	27260156	PANC0813	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.2995925626232855	[756]	[1159,918,1352,958]	5	hSpCas9	negative selection	8352411
43583020	43583043	6	+	27260156	PANC0813	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.3122584599677444	[724]	[1210,981,1114,940]	5	hSpCas9	negative selection	8352412
43601004	43601027	6	-	27260156	PANC0813	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.2133408419109042	[175]	[458,218,149,154]	3	hSpCas9	negative selection	8416659
43597801	43597824	6	+	27260156	PANC0813	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.1760355132605117	[280]	[318,345,277,230]	-3	hSpCas9	negative selection	8416660
43601017	43601040	6	+	27260156	PANC0813	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	0.07668212021115006	[713]	[992,873,810,868]	1	hSpCas9	negative selection	8416661
43583102	43583125	6	+	27260156	RDES	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.3581874645230195	[821]	[585,713,822,861]	-6	hSpCas9	negative selection	8473661
43597692	43597715	6	+	27260156	RDES	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.021212741984539707	[756]	[786,724,1051,1002]	0	hSpCas9	negative selection	8473662
43583020	43583043	6	+	27260156	RDES	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.447174170556748	[724]	[910,857,1326,1566]	7	hSpCas9	negative selection	8473663
43601004	43601027	6	-	27260156	RDES	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.18450258299882405	[175]	[127,127,261,213]	-3	hSpCas9	negative selection	8537910
43597801	43597824	6	+	27260156	RDES	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.17154875119162427	[280]	[222,164,377,423]	-3	hSpCas9	negative selection	8537911
43601017	43601040	6	+	27260156	RDES	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.1320457389955907	[713]	[719,735,688,846]	-2	hSpCas9	negative selection	8537912
43583102	43583125	6	+	27260156	PC3	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.35655631571269625	[821]	[366,438,1252,822]	-7	hSpCas9	negative selection	8594912
43597692	43597715	6	+	27260156	PC3	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.07593786409207459	[756]	[448,811,1389,506]	-2	hSpCas9	negative selection	8594913
43583020	43583043	6	+	27260156	PC3	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.09964537862151823	[724]	[532,732,1275,776]	2	hSpCas9	negative selection	8594914
43601004	43601027	6	-	27260156	PC3	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.2814931645372194	[175]	[66,113,379,132]	-6	hSpCas9	negative selection	8659161
43597801	43597824	6	+	27260156	PC3	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.41756898511773344	[280]	[118,240,192,301]	-7	hSpCas9	negative selection	8659162
43601017	43601040	6	+	27260156	PC3	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.2023645902771508	[713]	[472,538,862,693]	-4	hSpCas9	negative selection	8659163
43583102	43583125	6	+	27260156	PATU8988T	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.23359553856771387	[821]	[893,526,703,552]	-4	hSpCas9	negative selection	8716163
43597692	43597715	6	+	27260156	PATU8988T	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.024348557569562224	[756]	[495,857,653,896]	0	hSpCas9	negative selection	8716164
43583020	43583043	6	+	27260156	PATU8988T	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.5858630661976032	[724]	[607,1120,938,1588]	8	hSpCas9	negative selection	8716165
43601004	43601027	6	-	27260156	PATU8988T	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.19398189967469293	[175]	[92,231,189,272]	3	hSpCas9	negative selection	8780412
43597801	43597824	6	+	27260156	PATU8988T	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	0.24040842296508513	[280]	[256,338,406,276]	4	hSpCas9	negative selection	8780413
43601017	43601040	6	+	27260156	PATU8988T	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.19760736305889814	[713]	[356,919,682,463]	-3	hSpCas9	negative selection	8780414
43583102	43583125	6	+	27260156	T47D	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.39045891010147227	[821]	[664,716,760,780]	-7	hSpCas9	negative selection	8837414
43597692	43597715	6	+	27260156	T47D	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.0399745949962268	[756]	[1096,901,875,747]	0	hSpCas9	negative selection	8837415
43583020	43583043	6	+	27260156	T47D	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.27711855728474144	[724]	[1001,919,1122,1056]	6	hSpCas9	negative selection	8837416
43601004	43601027	6	-	27260156	T47D	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.21142575286921828	[175]	[201,156,177,172]	-5	hSpCas9	negative selection	8901663
43597801	43597824	6	+	27260156	T47D	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.10953563255268417	[280]	[276,360,247,323]	-2	hSpCas9	negative selection	8901664
43601017	43601040	6	+	27260156	T47D	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.14764042099282582	[713]	[771,748,748,732]	-3	hSpCas9	negative selection	8901665
43583102	43583125	6	+	27260156	SU8686	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.8964325480197982	[821]	[448,353,343,640]	-8	hSpCas9	negative selection	8958665
43597692	43597715	6	+	27260156	SU8686	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.26234801273216773	[756]	[694,576,565,662]	-4	hSpCas9	negative selection	8958666
43583020	43583043	6	+	27260156	SU8686	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.34746129855729946	[724]	[866,844,994,969]	6	hSpCas9	negative selection	8958667
43601004	43601027	6	-	27260156	SU8686	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-1.1910246611209412	[175]	[39,80,97,92]	-9	hSpCas9	negative selection	9022914
43597801	43597824	6	+	27260156	SU8686	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-1.068475032780111	[280]	[124,87,116,220]	-8	hSpCas9	negative selection	9022915
43601017	43601040	6	+	27260156	SU8686	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.5278969387777915	[713]	[351,530,480,628]	-7	hSpCas9	negative selection	9022916
43583102	43583125	6	+	27260156	SKES1	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.5179077499624652	[821]	[745,626,550,410]	-8	hSpCas9	negative selection	9079916
43597692	43597715	6	+	27260156	SKES1	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.11939511814709958	[756]	[713,850,941,759]	2	hSpCas9	negative selection	9079917
43583020	43583043	6	+	27260156	SKES1	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.2732663283459471	[724]	[832,903,803,936]	6	hSpCas9	negative selection	9079918
43601004	43601027	6	-	27260156	SKES1	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.14708471068490558	[175]	[255,213,128,188]	3	hSpCas9	negative selection	9144165
43597801	43597824	6	+	27260156	SKES1	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	0.14124757043278224	[280]	[399,427,305,145]	3	hSpCas9	negative selection	9144166
43601017	43601040	6	+	27260156	SKES1	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.13063701717185916	[713]	[651,747,593,617]	-3	hSpCas9	negative selection	9144167
43583102	43583125	6	+	27260156	TOV112D	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.3725702742646749	[821]	[553,1032,432,613]	-6	hSpCas9	negative selection	9201167
43597692	43597715	6	+	27260156	TOV112D	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	0.22235781007111	[756]	[902,709,1352,538]	4	hSpCas9	negative selection	9201168
43583020	43583043	6	+	27260156	TOV112D	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.38319429567430685	[724]	[930,1326,937,689]	7	hSpCas9	negative selection	9201169
43601004	43601027	6	-	27260156	TOV112D	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	-0.5018354039027175	[175]	[202,126,87,87]	-7	hSpCas9	negative selection	9265416
43597801	43597824	6	+	27260156	TOV112D	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.09283412051714668	[280]	[267,205,221,342]	-2	hSpCas9	negative selection	9265417
43601017	43601040	6	+	27260156	TOV112D	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.2817100363719939	[713]	[545,764,492,587]	-5	hSpCas9	negative selection	9265418
43583102	43583125	6	+	27260156	TC71	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.049663475758250586	[821]	[871,914,683,944]	-1	hSpCas9	negative selection	9322418
43597692	43597715	6	+	27260156	TC71	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.031352654284217296	[756]	[678,795,854,849]	-1	hSpCas9	negative selection	9322419
43583020	43583043	6	+	27260156	TC71	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.06066449088015824	[724]	[820,805,754,864]	1	hSpCas9	negative selection	9322420
43601004	43601027	6	-	27260156	TC71	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.2382728148203217	[175]	[339,181,145,221]	6	hSpCas9	negative selection	9386667
43597801	43597824	6	+	27260156	TC71	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	0.203815560731464	[280]	[420,296,339,326]	5	hSpCas9	negative selection	9386668
43601017	43601040	6	+	27260156	TC71	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.08203223348482824	[713]	[766,704,776,634]	-2	hSpCas9	negative selection	9386669
43583102	43583125	6	+	27260156	TC32	viability	CACAAGTTCGTGAGTCCCGTGGG	POLH	ENSG00000170734	-0.4208291407225806	[821]	[423,469,822,664]	-7	hSpCas9	negative selection	9443669
43597692	43597715	6	+	27260156	TC32	viability	TCAGAGGGGATGCGAAAACAAGG	POLH	ENSG00000170734	-0.010304469748006806	[756]	[675,472,888,879]	0	hSpCas9	negative selection	9443670
43583020	43583043	6	+	27260156	TC32	viability	AGTTATGAAGCTCGTGCATTTGG	POLH	ENSG00000170734	0.3998335661004788	[724]	[988,689,1133,830]	7	hSpCas9	negative selection	9443671
43601004	43601027	6	-	27260156	TC32	viability	GTTGGGCTTGTTTAGTCCACAGG	POLH	ENSG00000170734	0.03637214197872152	[175]	[123,124,251,206]	0	hSpCas9	negative selection	9507918
43597801	43597824	6	+	27260156	TC32	viability	AAATGAGAGCAGCCATAGAGAGG	POLH	ENSG00000170734	-0.7467030953975474	[280]	[140,54,191,287]	-9	hSpCas9	negative selection	9507919
43601017	43601040	6	+	27260156	TC32	viability	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	0.010635129732031956	[713]	[483,645,920,689]	0	hSpCas9	negative selection	9507920
43582340	43582363	6	+	27869803	HPAFII	viability after 27 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-0.05444180469524118	[173]	[116,63,NaN]	0	hSpCas9	negative selection	9596239
43597809	43597832	6	+	27869803	HPAFII	viability after 27 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	1.1408105494710412	[358]	[329,487,NaN]	8	hSpCas9	negative selection	9596240
43601017	43601040	6	+	27869803	HPAFII	viability after 27 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.13420873396822874	[630]	[352,259,NaN]	-1	hSpCas9	negative selection	9596241
43603918	43603941	6	-	27869803	HPAFII	viability after 27 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.40301500400810997	[571]	[539,278,NaN]	3	hSpCas9	negative selection	9596242
43604717	43604740	6	+	27869803	HPAFII	viability after 27 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	0.9909063897445325	[155]	[84,227,NaN]	7	hSpCas9	negative selection	9596243
43582340	43582363	6	+	27869803	HPAFII	viability after 15 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	0.308897196201648	[173]	[251,218,NaN]	3	hSpCas9	negative selection	9678688
43597809	43597832	6	+	27869803	HPAFII	viability after 15 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	0.17270565360049184	[358]	[720,256,NaN]	2	hSpCas9	negative selection	9678689
43601017	43601040	6	+	27869803	HPAFII	viability after 15 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.092130711893323	[630]	[650,626,NaN]	-1	hSpCas9	negative selection	9678690
43603918	43603941	6	-	27869803	HPAFII	viability after 15 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	-0.003969302949146991	[571]	[855,461,NaN]	0	hSpCas9	negative selection	9678691
43604717	43604740	6	+	27869803	HPAFII	viability after 15 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	1.044396916872104	[155]	[293,377,NaN]	9	hSpCas9	negative selection	9678692
43582340	43582363	6	+	27869803	ASPC1	viability after 36 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-0.714548442917817	[436]	[164,90,42]	-6	hSpCas9	negative selection	9761137
43597809	43597832	6	+	27869803	ASPC1	viability after 36 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	-0.042971727442640106	[900]	[290,414,224]	0	hSpCas9	negative selection	9761138
43601017	43601040	6	+	27869803	ASPC1	viability after 36 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.29640710882479704	[1934]	[842,274,556]	-3	hSpCas9	negative selection	9761139
43603918	43603941	6	-	27869803	ASPC1	viability after 36 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.41227742738485484	[1554]	[1174,801,333]	4	hSpCas9	negative selection	9761140
43604717	43604740	6	+	27869803	ASPC1	viability after 36 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	-0.6262616513232724	[562]	[131,68,168]	-6	hSpCas9	negative selection	9761141
43582340	43582363	6	+	27869803	PATU8988S	viability after 35 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-0.03997145741746699	[373]	[151,140,NaN]	0	hSpCas9	negative selection	9843586
43597809	43597832	6	+	27869803	PATU8988S	viability after 35 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	-0.21986190925304866	[670]	[251,211,NaN]	-2	hSpCas9	negative selection	9843587
43601017	43601040	6	+	27869803	PATU8988S	viability after 35 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	0.4324421861110834	[1470]	[805,792,NaN]	5	hSpCas9	negative selection	9843588
43603918	43603941	6	-	27869803	PATU8988S	viability after 35 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.3949910916579642	[1362]	[866,575,NaN]	4	hSpCas9	negative selection	9843589
43604717	43604740	6	+	27869803	PATU8988S	viability after 35 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	0.6935391935563172	[287]	[225,148,NaN]	7	hSpCas9	negative selection	9843590
43582340	43582363	6	+	27869803	PATU8988S	viability after 31 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-0.18002881494117173	[373]	[106,162,NaN]	-2	hSpCas9	negative selection	9926035
43597809	43597832	6	+	27869803	PATU8988S	viability after 31 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	-0.2700818680979964	[670]	[209,236,NaN]	-3	hSpCas9	negative selection	9926036
43601017	43601040	6	+	27869803	PATU8988S	viability after 31 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	0.48806972149286465	[1470]	[618,1081,NaN]	6	hSpCas9	negative selection	9926037
43603918	43603941	6	-	27869803	PATU8988S	viability after 31 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.2646311086422324	[1362]	[589,732,NaN]	3	hSpCas9	negative selection	9926038
43604717	43604740	6	+	27869803	PATU8988S	viability after 31 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	0.18511234447657954	[287]	[130,129,NaN]	2	hSpCas9	negative selection	9926039
43582340	43582363	6	+	27869803	HPAFII	viability after 35 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-0.1477209624670478	[173]	[47,114,NaN]	-1	hSpCas9	negative selection	10008484
43597809	43597832	6	+	27869803	HPAFII	viability after 35 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	1.2995272083010732	[358]	[214,708,NaN]	8	hSpCas9	negative selection	10008485
43601017	43601040	6	+	27869803	HPAFII	viability after 35 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	0.1001445727185879	[630]	[443,227,NaN]	0	hSpCas9	negative selection	10008486
43603918	43603941	6	-	27869803	HPAFII	viability after 35 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.7237042304100261	[571]	[655,277,NaN]	5	hSpCas9	negative selection	10008487
43604717	43604740	6	+	27869803	HPAFII	viability after 35 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	1.26001451196527	[155]	[119,266,NaN]	8	hSpCas9	negative selection	10008488
43582340	43582363	6	+	27869803	HPAFII	viability after 31 days	AGTGGTTGCTCTCGTGGACATGG	POLH	ENSG00000170734	-0.04765705078153315	[173]	[93,94,NaN]	0	hSpCas9	negative selection	10090933
43597809	43597832	6	+	27869803	HPAFII	viability after 31 days	GCAGCCATAGAGAGGGAGACTGG	POLH	ENSG00000170734	1.2488105079083462	[358]	[250,726,NaN]	8	hSpCas9	negative selection	10090934
43601017	43601040	6	+	27869803	HPAFII	viability after 31 days	CAAGCCCAACCGCCAAACCCTGG	POLH	ENSG00000170734	-0.09442086086377155	[630]	[402,253,NaN]	0	hSpCas9	negative selection	10090935
43603918	43603941	6	-	27869803	HPAFII	viability after 31 days	CCCTAGGATCTCAATGACAGAGG	POLH	ENSG00000170734	0.5046487341161936	[571]	[565,334,NaN]	3	hSpCas9	negative selection	10090936
43604717	43604740	6	+	27869803	HPAFII	viability after 31 days	AGCTCTTGCTACTCGGGAACAGG	POLH	ENSG00000170734	1.575282616446266	[155]	[157,372,NaN]	9	hSpCas9	negative selection	10090937
43597802	43597825	6	+	28162770	P31FUJ	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	0.2512313874559967	[147]	[206]	2	hSpCas9	negative selection	10214054
43583117	43583140	6	-	28162770	P31FUJ	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-0.172643221824184	[774]	[807]	-2	hSpCas9	negative selection	10214055
43603894	43603917	6	+	28162770	P31FUJ	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	-0.3035051957575805	[459]	[437]	-3	hSpCas9	negative selection	10214056
43604683	43604706	6	-	28162770	P31FUJ	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	0.20426160119446424	[129]	[175]	2	hSpCas9	negative selection	10214057
43583101	43583124	6	+	28162770	P31FUJ	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	1.0326589388139553	[98]	[237]	9	hSpCas9	negative selection	10214058
43597751	43597774	6	-	28162770	P31FUJ	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-1.2980936646660979	[112]	[53]	-7	hSpCas9	negative selection	10214059
43597778	43597801	6	+	28162770	P31FUJ	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	0.028341381960174772	[508]	[609]	0	hSpCas9	negative selection	10214060
43601057	43601080	6	-	28162770	P31FUJ	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	-0.13372243070637613	[210]	[225]	-1	hSpCas9	negative selection	10214061
43604647	43604670	6	+	28162770	P31FUJ	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	0.13719890349013442	[666]	[861]	1	hSpCas9	negative selection	10214062
43605262	43605285	6	+	28162770	P31FUJ	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	0.33423838830951513	[215]	[319]	3	hSpCas9	negative selection	10214063
43597802	43597825	6	+	28162770	TF1	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10383420
43583117	43583140	6	-	28162770	TF1	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	NaN	[NaN]	[220]	1	hSpCas9	negative selection	10383421
43603894	43603917	6	+	28162770	TF1	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	NaN	[NaN]	[132]	1	hSpCas9	negative selection	10383422
43604683	43604706	6	-	28162770	TF1	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10383423
43583101	43583124	6	+	28162770	TF1	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	NaN	[NaN]	[47]	1	hSpCas9	negative selection	10383424
43597751	43597774	6	-	28162770	TF1	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	NaN	[NaN]	[38]	1	hSpCas9	negative selection	10383425
43597778	43597801	6	+	28162770	TF1	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	NaN	[NaN]	[277]	1	hSpCas9	negative selection	10383426
43601057	43601080	6	-	28162770	TF1	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10383427
43604647	43604670	6	+	28162770	TF1	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	NaN	[NaN]	[424]	1	hSpCas9	negative selection	10383428
43605262	43605285	6	+	28162770	TF1	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	NaN	[NaN]	[106]	1	hSpCas9	negative selection	10383429
43597802	43597825	6	+	28162770	SKM1	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	0.6908110169433155	[40]	[116]	6	hSpCas9	negative selection	10552786
43583117	43583140	6	-	28162770	SKM1	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	0.08015097857985021	[121]	[227]	0	hSpCas9	negative selection	10552787
43603894	43603917	6	+	28162770	SKM1	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	0.19719186721130533	[111]	[226]	2	hSpCas9	negative selection	10552788
43604683	43604706	6	-	28162770	SKM1	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	0.20601267814759122	[50]	[103]	2	hSpCas9	negative selection	10552789
43583101	43583124	6	+	28162770	SKM1	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	0.30138071748327655	[27]	[60]	3	hSpCas9	negative selection	10552790
43597751	43597774	6	-	28162770	SKM1	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-1.023635559191656	[45]	[39]	-6	hSpCas9	negative selection	10552791
43597778	43597801	6	+	28162770	SKM1	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	0.4020790734672124	[121]	[284]	4	hSpCas9	negative selection	10552792
43601057	43601080	6	-	28162770	SKM1	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	-0.19581653457433634	[45]	[70]	-2	hSpCas9	negative selection	10552793
43604647	43604670	6	+	28162770	SKM1	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	0.5190352198130614	[104]	[265]	5	hSpCas9	negative selection	10552794
43605262	43605285	6	+	28162770	SKM1	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	-0.0850361038557993	[41]	[69]	0	hSpCas9	negative selection	10552795
43597802	43597825	6	+	28162770	SKM1	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	0.6908110169433155	[40]	[116]	6	hSpCas9	negative selection	10722152
43583117	43583140	6	-	28162770	SKM1	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	0.08015097857985021	[121]	[227]	0	hSpCas9	negative selection	10722153
43603894	43603917	6	+	28162770	SKM1	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	0.19719186721130533	[111]	[226]	2	hSpCas9	negative selection	10722154
43604683	43604706	6	-	28162770	SKM1	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	0.20601267814759122	[50]	[103]	2	hSpCas9	negative selection	10722155
43583101	43583124	6	+	28162770	SKM1	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	0.30138071748327655	[27]	[60]	3	hSpCas9	negative selection	10722156
43597751	43597774	6	-	28162770	SKM1	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-1.023635559191656	[45]	[39]	-6	hSpCas9	negative selection	10722157
43597778	43597801	6	+	28162770	SKM1	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	0.4020790734672124	[121]	[284]	4	hSpCas9	negative selection	10722158
43601057	43601080	6	-	28162770	SKM1	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	-0.19581653457433634	[45]	[70]	-2	hSpCas9	negative selection	10722159
43604647	43604670	6	+	28162770	SKM1	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	0.5190352198130614	[104]	[265]	5	hSpCas9	negative selection	10722160
43605262	43605285	6	+	28162770	SKM1	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	-0.0850361038557993	[41]	[69]	0	hSpCas9	negative selection	10722161
43597802	43597825	6	+	28162770	PL21	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	-2.5095186336811506	[156]	[11]	-9	hSpCas9	negative selection	10891518
43583117	43583140	6	-	28162770	PL21	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-0.1251012144388779	[435]	[173]	-1	hSpCas9	negative selection	10891519
43603894	43603917	6	+	28162770	PL21	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	-1.4314729795306576	[439]	[70]	-7	hSpCas9	negative selection	10891520
43604683	43604706	6	-	28162770	PL21	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	0.00660205582505724	[230]	[100]	0	hSpCas9	negative selection	10891521
43583101	43583124	6	+	28162770	PL21	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	-0.8136661850357104	[104]	[25]	-5	hSpCas9	negative selection	10891522
43597751	43597774	6	-	28162770	PL21	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-1.1724145534680104	[144]	[27]	-7	hSpCas9	negative selection	10891523
43597778	43597801	6	+	28162770	PL21	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	0.667265624916618	[407]	[281]	6	hSpCas9	negative selection	10891524
43601057	43601080	6	-	28162770	PL21	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	-1.1984097620009546	[115]	[21]	-7	hSpCas9	negative selection	10891525
43604647	43604670	6	+	28162770	PL21	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	-0.4886586972163758	[431]	[133]	-3	hSpCas9	negative selection	10891526
43605262	43605285	6	+	28162770	PL21	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	-0.4705527602577199	[155]	[48]	-3	hSpCas9	negative selection	10891527
43597802	43597825	6	+	28162770	P31FUJ	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	0.2512313874559967	[147]	[206]	2	hSpCas9	negative selection	11060884
43583117	43583140	6	-	28162770	P31FUJ	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-0.172643221824184	[774]	[807]	-2	hSpCas9	negative selection	11060885
43603894	43603917	6	+	28162770	P31FUJ	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	-0.3035051957575805	[459]	[437]	-3	hSpCas9	negative selection	11060886
43604683	43604706	6	-	28162770	P31FUJ	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	0.20426160119446424	[129]	[175]	2	hSpCas9	negative selection	11060887
43583101	43583124	6	+	28162770	P31FUJ	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	1.0326589388139553	[98]	[237]	9	hSpCas9	negative selection	11060888
43597751	43597774	6	-	28162770	P31FUJ	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-1.2980936646660979	[112]	[53]	-7	hSpCas9	negative selection	11060889
43597778	43597801	6	+	28162770	P31FUJ	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	0.028341381960174772	[508]	[609]	0	hSpCas9	negative selection	11060890
43601057	43601080	6	-	28162770	P31FUJ	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	-0.13372243070637613	[210]	[225]	-1	hSpCas9	negative selection	11060891
43604647	43604670	6	+	28162770	P31FUJ	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	0.13719890349013442	[666]	[861]	1	hSpCas9	negative selection	11060892
43605262	43605285	6	+	28162770	P31FUJ	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	0.33423838830951513	[215]	[319]	3	hSpCas9	negative selection	11060893
43597802	43597825	6	+	28162770	OCIAML5	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	-1.0024834134170955	[100]	[90]	-6	hSpCas9	negative selection	11230250
43583117	43583140	6	-	28162770	OCIAML5	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-0.4109667749989572	[287]	[390]	-3	hSpCas9	negative selection	11230251
43603894	43603917	6	+	28162770	OCIAML5	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	0.23444242239067792	[177]	[377]	2	hSpCas9	negative selection	11230252
43604683	43604706	6	-	28162770	OCIAML5	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	0.03922716969350293	[61]	[114]	0	hSpCas9	negative selection	11230253
43583101	43583124	6	+	28162770	OCIAML5	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	-0.355640744744498	[55]	[78]	-3	hSpCas9	negative selection	11230254
43597751	43597774	6	-	28162770	OCIAML5	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-0.6764950062805424	[84]	[95]	-4	hSpCas9	negative selection	11230255
43597778	43597801	6	+	28162770	OCIAML5	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	-0.3123333241358386	[215]	[313]	-2	hSpCas9	negative selection	11230256
43601057	43601080	6	-	28162770	OCIAML5	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	0.6784481458347826	[71]	[207]	6	hSpCas9	negative selection	11230257
43604647	43604670	6	+	28162770	OCIAML5	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	-0.16458915951690667	[343]	[553]	-1	hSpCas9	negative selection	11230258
43605262	43605285	6	+	28162770	OCIAML5	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	-0.08850676668607771	[128]	[218]	0	hSpCas9	negative selection	11230259
43597802	43597825	6	+	28162770	EOL1	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	0.25546464968515153	[255]	[160]	2	hSpCas9	negative selection	11399616
43583117	43583140	6	-	28162770	EOL1	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-1.167122056741857	[600]	[140]	-7	hSpCas9	negative selection	11399617
43603894	43603917	6	+	28162770	EOL1	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	-0.8984415664290388	[834]	[235]	-6	hSpCas9	negative selection	11399618
43604683	43604706	6	-	28162770	EOL1	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	-0.4057196242295573	[346]	[137]	-3	hSpCas9	negative selection	11399619
43583101	43583124	6	+	28162770	EOL1	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	-0.5889795911076726	[196]	[68]	-4	hSpCas9	negative selection	11399620
43597751	43597774	6	-	28162770	EOL1	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-0.22745532187451548	[259]	[116]	-2	hSpCas9	negative selection	11399621
43597778	43597801	6	+	28162770	EOL1	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	0.1963791256414873	[544]	[328]	1	hSpCas9	negative selection	11399622
43601057	43601080	6	-	28162770	EOL1	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	-1.2680973063718615	[159]	[34]	-7	hSpCas9	negative selection	11399623
43604647	43604670	6	+	28162770	EOL1	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	-0.4413719611436182	[615]	[238]	-3	hSpCas9	negative selection	11399624
43605262	43605285	6	+	28162770	EOL1	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	0.09521815925566884	[214]	[120]	0	hSpCas9	negative selection	11399625
43597802	43597825	6	+	28162770	MOLM13	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	-0.8474660594192972	[218]	[87]	-5	hSpCas9	negative selection	11568982
43583117	43583140	6	-	28162770	MOLM13	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-1.5321106184554214	[591]	[147]	-6	hSpCas9	negative selection	11568983
43603894	43603917	6	+	28162770	MOLM13	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	0.04615722969172653	[575]	[429]	0	hSpCas9	negative selection	11568984
43604683	43604706	6	-	28162770	MOLM13	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	0.714982243509351	[272]	[323]	5	hSpCas9	negative selection	11568985
43583101	43583124	6	+	28162770	MOLM13	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	0.3804265402942394	[135]	[127]	2	hSpCas9	negative selection	11568986
43597751	43597774	6	-	28162770	MOLM13	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-1.6866876555642976	[186]	[41]	-7	hSpCas9	negative selection	11568987
43597778	43597801	6	+	28162770	MOLM13	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	-0.22653909856265164	[478]	[295]	-1	hSpCas9	negative selection	11568988
43601057	43601080	6	-	28162770	MOLM13	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	-2.1541624379117974	[196]	[31]	-7	hSpCas9	negative selection	11568989
43604647	43604670	6	+	28162770	MOLM13	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	-1.4065797363715624	[890]	[242]	-6	hSpCas9	negative selection	11568990
43605262	43605285	6	+	28162770	MOLM13	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	-1.1776146611116278	[218]	[69]	-6	hSpCas9	negative selection	11568991
43597802	43597825	6	+	28162770	HEL	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	-0.16822734360962616	[199]	[113]	-1	hSpCas9	negative selection	11738348
43583117	43583140	6	-	28162770	HEL	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-1.3065303658787133	[474]	[122]	-6	hSpCas9	negative selection	11738349
43603894	43603917	6	+	28162770	HEL	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	0.11129184060620245	[515]	[356]	0	hSpCas9	negative selection	11738350
43604683	43604706	6	-	28162770	HEL	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	-0.15117055899229562	[266]	[153]	-1	hSpCas9	negative selection	11738351
43583101	43583124	6	+	28162770	HEL	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	-0.6606533114495778	[115]	[46]	-4	hSpCas9	negative selection	11738352
43597751	43597774	6	-	28162770	HEL	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-2.025116677069144	[196]	[30]	-8	hSpCas9	negative selection	11738353
43597778	43597801	6	+	28162770	HEL	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	-0.5663567667226332	[503]	[217]	-4	hSpCas9	negative selection	11738354
43601057	43601080	6	-	28162770	HEL	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	0.040902512714804495	[128]	[84]	0	hSpCas9	negative selection	11738355
43604647	43604670	6	+	28162770	HEL	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	-0.5601164445442578	[708]	[307]	-4	hSpCas9	negative selection	11738356
43605262	43605285	6	+	28162770	HEL	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	-0.6328956106130705	[183]	[75]	-4	hSpCas9	negative selection	11738357
43597802	43597825	6	+	28162770	MV411	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	-0.3899923698325165	[111]	[71]	-3	hSpCas9	negative selection	11907714
43583117	43583140	6	-	28162770	MV411	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-0.8621869403917228	[409]	[189]	-5	hSpCas9	negative selection	11907715
43603894	43603917	6	+	28162770	MV411	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	0.11986049972331148	[448]	[410]	1	hSpCas9	negative selection	11907716
43604683	43604706	6	-	28162770	MV411	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	0.16600995143892924	[163]	[154]	1	hSpCas9	negative selection	11907717
43583101	43583124	6	+	28162770	MV411	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	-0.13722629945254983	[93]	[71]	-1	hSpCas9	negative selection	11907718
43597751	43597774	6	-	28162770	MV411	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-1.0521227310761323	[159]	[64]	-6	hSpCas9	negative selection	11907719
43597778	43597801	6	+	28162770	MV411	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	-0.19891971170887401	[356]	[261]	-1	hSpCas9	negative selection	11907720
43601057	43601080	6	-	28162770	MV411	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	0.44131728437681034	[145]	[166]	4	hSpCas9	negative selection	11907721
43604647	43604670	6	+	28162770	MV411	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	0.2509520349590124	[409]	[410]	2	hSpCas9	negative selection	11907722
43605262	43605285	6	+	28162770	MV411	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	0.07101098339850775	[138]	[122]	0	hSpCas9	negative selection	11907723
43597802	43597825	6	+	28162770	MONOMAC1	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	0.5508998649276557	[130]	[219]	5	hSpCas9	negative selection	12077080
43583117	43583140	6	-	28162770	MONOMAC1	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-0.5336002883153125	[321]	[254]	-4	hSpCas9	negative selection	12077081
43603894	43603917	6	+	28162770	MONOMAC1	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	-0.5969674539481891	[284]	[215]	-5	hSpCas9	negative selection	12077082
43604683	43604706	6	-	28162770	MONOMAC1	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	-0.11242461934461231	[148]	[157]	-1	hSpCas9	negative selection	12077083
43583101	43583124	6	+	28162770	MONOMAC1	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	0.022928836882354253	[84]	[98]	0	hSpCas9	negative selection	12077084
43597751	43597774	6	-	28162770	MONOMAC1	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-1.0201590849754745	[114]	[64]	-7	hSpCas9	negative selection	12077085
43597778	43597801	6	+	28162770	MONOMAC1	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	0.28511484807782694	[251]	[351]	3	hSpCas9	negative selection	12077086
43601057	43601080	6	-	28162770	MONOMAC1	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	0.7463796245740788	[64]	[124]	7	hSpCas9	negative selection	12077087
43604647	43604670	6	+	28162770	MONOMAC1	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	0.35983334663224953	[241]	[355]	3	hSpCas9	negative selection	12077088
43605262	43605285	6	+	28162770	MONOMAC1	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	-0.6018785792325092	[93]	[70]	-5	hSpCas9	negative selection	12077089
43597802	43597825	6	+	28162770	OCIAML2	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	-0.45073026780445624	[35]	[145]	-4	hSpCas9	negative selection	12246446
43583117	43583140	6	-	28162770	OCIAML2	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-1.3175504952377721	[66]	[148]	-7	hSpCas9	negative selection	12246447
43603894	43603917	6	+	28162770	OCIAML2	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	-0.18328196206494318	[75]	[370]	-1	hSpCas9	negative selection	12246448
43604683	43604706	6	-	28162770	OCIAML2	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	-0.12270652182185429	[32]	[167]	-1	hSpCas9	negative selection	12246449
43583101	43583124	6	+	28162770	OCIAML2	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	-1.157471939982531	[32]	[81]	-6	hSpCas9	negative selection	12246450
43597751	43597774	6	-	28162770	OCIAML2	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	-1.780969945854312	[30]	[49]	-8	hSpCas9	negative selection	12246451
43597778	43597801	6	+	28162770	OCIAML2	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	-0.5257713794346223	[79]	[307]	-4	hSpCas9	negative selection	12246452
43601057	43601080	6	-	28162770	OCIAML2	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	-0.8242667798568616	[22]	[71]	-5	hSpCas9	negative selection	12246453
43604647	43604670	6	+	28162770	OCIAML2	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	0.19922157306550792	[65]	[419]	2	hSpCas9	negative selection	12246454
43605262	43605285	6	+	28162770	OCIAML2	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	-0.06853138167081563	[20]	[110]	0	hSpCas9	negative selection	12246455
43597802	43597825	6	+	28162770	OCIAML3	viability	AATGAGAGCAGCCATAGAGAGGG	POLH	ENSG00000170734	0.05170889147608926	[30]	[96]	0	hSpCas9	negative selection	12415812
43583117	43583140	6	-	28162770	OCIAML3	viability	GGTGAGGTTAGCTTTCCCACGGG	POLH	ENSG00000170734	-0.39370898983833214	[140]	[323]	-3	hSpCas9	negative selection	12415813
43603894	43603917	6	+	28162770	OCIAML3	viability	GTAGTCTTGGAGGAAAGCTAGGG	POLH	ENSG00000170734	0.7143739227252512	[106]	[529]	6	hSpCas9	negative selection	12415814
43604683	43604706	6	-	28162770	OCIAML3	viability	GAAGTTCTTACTACAGCCAATGG	POLH	ENSG00000170734	0.25398926623078694	[34]	[125]	2	hSpCas9	negative selection	12415815
43583101	43583124	6	+	28162770	OCIAML3	viability	GCACAAGTTCGTGAGTCCCGTGG	POLH	ENSG00000170734	-0.10606959399787169	[40]	[114]	-1	hSpCas9	negative selection	12415816
43597751	43597774	6	-	28162770	OCIAML3	viability	GCTGCAGGTCTGGAGAGGTGAGG	POLH	ENSG00000170734	0.028429565815655866	[37]	[116]	0	hSpCas9	negative selection	12415817
43597778	43597801	6	+	28162770	OCIAML3	viability	CGTGGGAGCAGTGATTGTGGAGG	POLH	ENSG00000170734	1.2943470038469276	[93]	[695]	9	hSpCas9	negative selection	12415818
43601057	43601080	6	-	28162770	OCIAML3	viability	GGCATTTGGCTGAAGAGCTGTGG	POLH	ENSG00000170734	-0.6505911686905306	[38]	[74]	-5	hSpCas9	negative selection	12415819
43604647	43604670	6	+	28162770	OCIAML3	viability	AACATGATCCAGTTAAACCCAGG	POLH	ENSG00000170734	0.49778483559532716	[136]	[583]	4	hSpCas9	negative selection	12415820
43605262	43605285	6	+	28162770	OCIAML3	viability	GTGGCTGTTGCAATTAGCCCAGG	POLH	ENSG00000170734	0.7685624390605452	[34]	[179]	7	hSpCas9	negative selection	12415821