Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5444
• Symbol: PON1
• Description: paraoxonase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PON1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
95324455	95324478	7	+	26472758	Jiyoye	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.43317059003881775	[164]	[167]	3	hSpCas9	negative selection	123997
95324397	95324420	7	+	26472758	Jiyoye	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	0.6767824412631536	[72]	[87]	5	hSpCas9	negative selection	123998
95311542	95311565	7	+	26472758	Jiyoye	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	1.419049481794165	[120]	[243]	8	hSpCas9	negative selection	123999
95308014	95308037	7	-	26472758	Jiyoye	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	-0.5070947444682428	[48]	[25]	-4	hSpCas9	negative selection	124000
95302266	95302289	7	-	26472758	Jiyoye	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	1.8666070001431707	[11]	[32]	8	hSpCas9	negative selection	124001
95302240	95302263	7	+	26472758	Jiyoye	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	-0.0817111476602354	[166]	[118]	0	hSpCas9	negative selection	124002
95316748	95316771	7	-	26472758	Jiyoye	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.28797003696570567	[135]	[83]	-2	hSpCas9	negative selection	124003
95311554	95311577	7	-	26472758	Jiyoye	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	-0.14844315763313842	[437]	[297]	-1	hSpCas9	negative selection	124004
95302255	95302278	7	+	26472758	Jiyoye	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.483124234739172	[36]	[38]	3	hSpCas9	negative selection	124005
95324430	95324453	7	+	26472758	Jiyoye	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	0.6317356395250316	[189]	[221]	4	hSpCas9	negative selection	124006
95324455	95324478	7	+	26472758	KBM7	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.07167913155707462	[858,601]	[417,300]	0	hSpCas9	negative selection	315115
95324397	95324420	7	+	26472758	KBM7	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	0.31293035793941804	[391,309]	[192,212]	3	hSpCas9	negative selection	315116
95311542	95311565	7	+	26472758	KBM7	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.15494775000913882	[748,317]	[285,253]	1	hSpCas9	negative selection	315117
95308014	95308037	7	-	26472758	KBM7	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	0.5462868603032137	[175,162]	[59,166]	6	hSpCas9	negative selection	315118
95302266	95302289	7	-	26472758	KBM7	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-1.5121558754158715	[550,561]	[105,79]	-8	hSpCas9	negative selection	315119
95302240	95302263	7	+	26472758	KBM7	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	0.12003181296101306	[704,346]	[246,272]	1	hSpCas9	negative selection	315120
95316748	95316771	7	-	26472758	KBM7	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.16346502664611934	[463,414]	[120,240]	-1	hSpCas9	negative selection	315121
95311554	95311577	7	-	26472758	KBM7	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	0.3807094809945548	[1708,1708]	[1007,1089]	4	hSpCas9	negative selection	315122
95302255	95302278	7	+	26472758	KBM7	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.9006849357326275	[208,147]	[178,132]	8	hSpCas9	negative selection	315123
95324430	95324453	7	+	26472758	KBM7	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.052932050902607	[1041,1017]	[457,477]	0	hSpCas9	negative selection	315124
95324455	95324478	7	+	26472758	Raji	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.3079773664314863	[361]	[103]	3	hSpCas9	negative selection	506233
95324397	95324420	7	+	26472758	Raji	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	-0.10297633046795124	[198]	[42]	-1	hSpCas9	negative selection	506234
95311542	95311565	7	+	26472758	Raji	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.7276791092070365	[241]	[92]	6	hSpCas9	negative selection	506235
95308014	95308037	7	-	26472758	Raji	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	-0.322604305371216	[96]	[17]	-3	hSpCas9	negative selection	506236
95302266	95302289	7	-	26472758	Raji	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-2.2772803148617253	[187]	[8]	-9	hSpCas9	negative selection	506237
95302240	95302263	7	+	26472758	Raji	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	0.6492773142028698	[271]	[98]	6	hSpCas9	negative selection	506238
95316748	95316771	7	-	26472758	Raji	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.4104647694890195	[251]	[43]	-3	hSpCas9	negative selection	506239
95311554	95311577	7	-	26472758	Raji	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	-0.051711532867961374	[928]	[207]	0	hSpCas9	negative selection	506240
95302255	95302278	7	+	26472758	Raji	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.6625986927007036	[97]	[35]	6	hSpCas9	negative selection	506241
95324430	95324453	7	+	26472758	Raji	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.27879910123305907	[527]	[100]	-2	hSpCas9	negative selection	506242
95324455	95324478	7	+	26472758	K562	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.42752424005378986	[568]	[645]	3	hSpCas9	negative selection	697351
95324397	95324420	7	+	26472758	K562	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	-0.38400172873848515	[336]	[217]	-3	hSpCas9	negative selection	697352
95311542	95311565	7	+	26472758	K562	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.3997730306111348	[386]	[430]	3	hSpCas9	negative selection	697353
95308014	95308037	7	-	26472758	K562	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	-0.11206658925728386	[168]	[131]	-1	hSpCas9	negative selection	697354
95302266	95302289	7	-	26472758	K562	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-2.4940182537164275	[326]	[48]	-8	hSpCas9	negative selection	697355
95302240	95302263	7	+	26472758	K562	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	0.17706345986468208	[569]	[543]	1	hSpCas9	negative selection	697356
95316748	95316771	7	-	26472758	K562	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	1.2558234909386963	[314]	[634]	9	hSpCas9	negative selection	697357
95311554	95311577	7	-	26472758	K562	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	-0.157720544392991	[1261]	[954]	-1	hSpCas9	negative selection	697358
95302255	95302278	7	+	26472758	K562	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-1.7555812723335533	[131]	[32]	-7	hSpCas9	negative selection	697359
95324430	95324453	7	+	26472758	K562	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.28212708682938736	[725]	[503]	-2	hSpCas9	negative selection	697360
95302255	95302278	7	+	26627737	DLD1	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	1.0775484825699513	[264]	[196,183,147]	8	hSpCas9	negative selection	837450
95308053	95308076	7	-	26627737	DLD1	viability	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	0.03965813154429071	[337]	[89,129,106]	0	hSpCas9	negative selection	837451
95311539	95311562	7	+	26627737	DLD1	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.6961415327954199	[261]	[169,114,114]	7	hSpCas9	negative selection	837452
95316748	95316771	7	-	26627737	DLD1	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.11788404259903196	[202]	[53,41,75]	-1	hSpCas9	negative selection	837453
95318368	95318391	7	-	26627737	DLD1	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	1.0963199597435098	[393]	[269,234,280]	8	hSpCas9	negative selection	837454
95324455	95324478	7	+	26627737	DLD1	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	1.099178510728704	[234]	[193,168,115]	8	hSpCas9	negative selection	837455
95302255	95302278	7	+	26627737	GBM cells	viability after 5 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.3603213373025636	[198]	[142,130]	5	hSpCas9	negative selection	919765
95308053	95308076	7	-	26627737	GBM cells	viability after 5 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-0.7212380542977707	[165]	[60,46]	-8	hSpCas9	negative selection	919766
95311539	95311562	7	+	26627737	GBM cells	viability after 5 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	-0.1632426011768836	[165]	[72,85]	-3	hSpCas9	negative selection	919767
95316748	95316771	7	-	26627737	GBM cells	viability after 5 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.20578350378100763	[99]	[49,42]	-3	hSpCas9	negative selection	919768
95318368	95318391	7	-	26627737	GBM cells	viability after 5 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.07043591227412976	[325]	[151,180]	-1	hSpCas9	negative selection	919769
95324455	95324478	7	+	26627737	GBM cells	viability after 5 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.556455718428376	[132]	[54,41]	-7	hSpCas9	negative selection	919770
95302255	95302278	7	+	26627737	GBM cells	viability after 13 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.5084024040973013	[198]	[157,149]	6	hSpCas9	negative selection	1002080
95308053	95308076	7	-	26627737	GBM cells	viability after 13 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-0.27876006342644555	[165]	[76,71]	-3	hSpCas9	negative selection	1002081
95311539	95311562	7	+	26627737	GBM cells	viability after 13 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	-0.4974185351934296	[165]	[81,48]	-5	hSpCas9	negative selection	1002082
95316748	95316771	7	-	26627737	GBM cells	viability after 13 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.9776956451175032	[99]	[26,27]	-8	hSpCas9	negative selection	1002083
95318368	95318391	7	-	26627737	GBM cells	viability after 13 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.4025163130656373	[325]	[108,153]	-5	hSpCas9	negative selection	1002084
95324455	95324478	7	+	26627737	GBM cells	viability after 13 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.7963516793223151	[132]	[40,41]	-7	hSpCas9	negative selection	1002085
95302255	95302278	7	+	26627737	GBM cells	viability after 21 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.3570035843081387	[198]	[150,126]	3	hSpCas9	negative selection	1084395
95308053	95308076	7	-	26627737	GBM cells	viability after 21 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-0.043411832159387376	[165]	[98,76]	0	hSpCas9	negative selection	1084396
95311539	95311562	7	+	26627737	GBM cells	viability after 21 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	-0.8699903720938283	[165]	[52,45]	-6	hSpCas9	negative selection	1084397
95316748	95316771	7	-	26627737	GBM cells	viability after 21 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.4440964667985281	[99]	[75,71]	4	hSpCas9	negative selection	1084398
95318368	95318391	7	-	26627737	GBM cells	viability after 21 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.45490852936260134	[325]	[135,122]	-4	hSpCas9	negative selection	1084399
95324455	95324478	7	+	26627737	GBM cells	viability after 21 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.8830854728950241	[132]	[34,42]	-6	hSpCas9	negative selection	1084400
95302255	95302278	7	+	26627737	RPE1	viability after 9 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.10180981334703837	[939]	[310,321]	0	hSpCas9	negative selection	1166710
95308053	95308076	7	-	26627737	RPE1	viability after 9 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-0.7687083832831676	[1031]	[100,303]	-5	hSpCas9	negative selection	1166711
95311539	95311562	7	+	26627737	RPE1	viability after 9 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.12183513849125577	[551]	[208,160]	0	hSpCas9	negative selection	1166712
95316748	95316771	7	-	26627737	RPE1	viability after 9 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.33261008496865374	[347]	[141,130]	2	hSpCas9	negative selection	1166713
95318368	95318391	7	-	26627737	RPE1	viability after 9 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.5971555382843158	[1113]	[130,358]	-4	hSpCas9	negative selection	1166714
95324455	95324478	7	+	26627737	RPE1	viability after 9 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-1.0835151778547258	[672]	[153,28]	-7	hSpCas9	negative selection	1166715
95302255	95302278	7	+	26627737	RPE1	viability after 12 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-0.1562195896079806	[939]	[230,221]	-1	hSpCas9	negative selection	1249025
95308053	95308076	7	-	26627737	RPE1	viability after 12 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-0.5295094264635332	[1031]	[143,242]	-4	hSpCas9	negative selection	1249026
95311539	95311562	7	+	26627737	RPE1	viability after 12 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.6448570877066613	[551]	[227,235]	4	hSpCas9	negative selection	1249027
95316748	95316771	7	-	26627737	RPE1	viability after 12 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.720222093110541	[347]	[222,80]	4	hSpCas9	negative selection	1249028
95318368	95318391	7	-	26627737	RPE1	viability after 12 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.05178065799390763	[1113]	[160,423]	0	hSpCas9	negative selection	1249029
95324455	95324478	7	+	26627737	RPE1	viability after 12 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-1.0309786322074828	[672]	[104,70]	-6	hSpCas9	negative selection	1249030
95302255	95302278	7	+	26627737	RPE1	viability after 15 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-0.14959210395149544	[939]	[311,169]	-1	hSpCas9	negative selection	1331340
95308053	95308076	7	-	26627737	RPE1	viability after 15 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-0.48013721435625495	[1031]	[164,251]	-3	hSpCas9	negative selection	1331341
95311539	95311562	7	+	26627737	RPE1	viability after 15 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.511883140181512	[551]	[213,230]	3	hSpCas9	negative selection	1331342
95316748	95316771	7	-	26627737	RPE1	viability after 15 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.5916070876429812	[347]	[128,166]	4	hSpCas9	negative selection	1331343
95318368	95318391	7	-	26627737	RPE1	viability after 15 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.1849334704833332	[1113]	[204,505]	1	hSpCas9	negative selection	1331344
95324455	95324478	7	+	26627737	RPE1	viability after 15 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.4196146384247429	[672]	[179,105]	-3	hSpCas9	negative selection	1331345
95302255	95302278	7	+	26627737	RPE1	viability after 18 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-0.11333168221617668	[939]	[263,202]	0	hSpCas9	negative selection	1413655
95308053	95308076	7	-	26627737	RPE1	viability after 18 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-0.5824001842144804	[1031]	[83,294]	-4	hSpCas9	negative selection	1413656
95311539	95311562	7	+	26627737	RPE1	viability after 18 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.9273233543250503	[551]	[189,382]	5	hSpCas9	negative selection	1413657
95316748	95316771	7	-	26627737	RPE1	viability after 18 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.0036393716629843365	[347]	[83,104]	0	hSpCas9	negative selection	1413658
95318368	95318391	7	-	26627737	RPE1	viability after 18 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.04192362404708233	[1113]	[350,228]	0	hSpCas9	negative selection	1413659
95324455	95324478	7	+	26627737	RPE1	viability after 18 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.9086930197940712	[672]	[132,57]	-5	hSpCas9	negative selection	1413660
95302255	95302278	7	+	26627737	HeLa	viability after 8 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-0.6601062582937339	[401]	[91,95,137]	-6	hSpCas9	negative selection	1495970
95308053	95308076	7	-	26627737	HeLa	viability after 8 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-0.10332645822299202	[290]	[116,215,26]	-1	hSpCas9	negative selection	1495971
95311539	95311562	7	+	26627737	HeLa	viability after 8 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	-0.6182992581360935	[247]	[134,2,85]	-6	hSpCas9	negative selection	1495972
95316748	95316771	7	-	26627737	HeLa	viability after 8 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.08341135436011027	[179]	[117,76,38]	-1	hSpCas9	negative selection	1495973
95318368	95318391	7	-	26627737	HeLa	viability after 8 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.06688932207615335	[449]	[225,179,164]	0	hSpCas9	negative selection	1495974
95324455	95324478	7	+	26627737	HeLa	viability after 8 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.6706094804955929	[214]	[49,44,77]	-6	hSpCas9	negative selection	1495975
95302255	95302278	7	+	26627737	HeLa	viability after 12 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-1.1466536430830356	[401]	[19,60,143]	-8	hSpCas9	negative selection	1578285
95308053	95308076	7	-	26627737	HeLa	viability after 12 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-0.28817902775848736	[290]	[224,61,15]	-3	hSpCas9	negative selection	1578286
95311539	95311562	7	+	26627737	HeLa	viability after 12 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.9266244294514894	[247]	[304,115,174]	7	hSpCas9	negative selection	1578287
95316748	95316771	7	-	26627737	HeLa	viability after 12 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.19617140235152886	[179]	[111,56,27]	-2	hSpCas9	negative selection	1578288
95318368	95318391	7	-	26627737	HeLa	viability after 12 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.2794175759710646	[449]	[20,245,178]	-2	hSpCas9	negative selection	1578289
95324455	95324478	7	+	26627737	HeLa	viability after 12 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.022380622043144616	[214]	[117,132,15]	0	hSpCas9	negative selection	1578290
95302255	95302278	7	+	26627737	HeLa	viability after 15 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-1.444852476288277	[401]	[109,5,63]	-8	hSpCas9	negative selection	1660600
95308053	95308076	7	-	26627737	HeLa	viability after 15 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-0.8067385525850819	[290]	[95,72,30]	-6	hSpCas9	negative selection	1660601
95311539	95311562	7	+	26627737	HeLa	viability after 15 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	-0.10552910941044402	[247]	[182,7,88]	-1	hSpCas9	negative selection	1660602
95316748	95316771	7	-	26627737	HeLa	viability after 15 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.8764529952560953	[179]	[27,86,1]	-6	hSpCas9	negative selection	1660603
95318368	95318391	7	-	26627737	HeLa	viability after 15 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.4755841509199704	[449]	[66,137,195]	-4	hSpCas9	negative selection	1660604
95324455	95324478	7	+	26627737	HeLa	viability after 15 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-3.2459680865074683	[214]	[12,12,0]	-9	hSpCas9	negative selection	1660605
95302255	95302278	7	+	26627737	HeLa	viability after 18 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-1.4948240633197738	[401]	[68,5,63]	-8	hSpCas9	negative selection	1742915
95308053	95308076	7	-	26627737	HeLa	viability after 18 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-0.7846720446722477	[290]	[61,65,30]	-6	hSpCas9	negative selection	1742916
95311539	95311562	7	+	26627737	HeLa	viability after 18 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	-0.017283953696339616	[247]	[133,6,88]	0	hSpCas9	negative selection	1742917
95316748	95316771	7	-	26627737	HeLa	viability after 18 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.8954879205369477	[179]	[20,67,1]	-7	hSpCas9	negative selection	1742918
95318368	95318391	7	-	26627737	HeLa	viability after 18 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.46196254301828055	[449]	[45,115,195]	-4	hSpCas9	negative selection	1742919
95324455	95324478	7	+	26627737	HeLa	viability after 18 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-3.1476251095713392	[214]	[8,11,0]	-9	hSpCas9	negative selection	1742920
95302255	95302278	7	+	26627737	HCT116	viability after 6 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-2.246750616433959	[545]	[39,5]	-8	hSpCas9	negative selection	1825230
95308053	95308076	7	-	26627737	HCT116	viability after 6 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-2.962713041046634	[356]	[12,3]	-9	hSpCas9	negative selection	1825231
95311539	95311562	7	+	26627737	HCT116	viability after 6 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	-0.10977428971484104	[338]	[118,10]	0	hSpCas9	negative selection	1825232
95316748	95316771	7	-	26627737	HCT116	viability after 6 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-1.8888347872208664	[533]	[12,27]	-8	hSpCas9	negative selection	1825233
95318368	95318391	7	-	26627737	HCT116	viability after 6 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.156827721270912	[751]	[116,99]	-1	hSpCas9	negative selection	1825234
95324455	95324478	7	+	26627737	HCT116	viability after 6 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.05518457443364033	[445]	[48,85]	0	hSpCas9	negative selection	1825235
95302255	95302278	7	+	26627737	HCT116	viability after 8 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.24710120641826883	[242]	[116,117,239]	2	hSpCas9	negative selection	1907545
95308053	95308076	7	-	26627737	HCT116	viability after 8 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	0.3117945178440226	[188]	[130,140,115]	3	hSpCas9	negative selection	1907546
95311539	95311562	7	+	26627737	HCT116	viability after 8 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	-0.11894713710567872	[136]	[34,108,63]	-1	hSpCas9	negative selection	1907547
95316748	95316771	7	-	26627737	HCT116	viability after 8 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-1.1101233679329932	[226]	[60,63,48]	-8	hSpCas9	negative selection	1907548
95318368	95318391	7	-	26627737	HCT116	viability after 8 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.9215438170621999	[261]	[385,296,140]	8	hSpCas9	negative selection	1907549
95324455	95324478	7	+	26627737	HCT116	viability after 8 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-1.3063766178301863	[455]	[135,116,52]	-9	hSpCas9	negative selection	1907550
95302255	95302278	7	+	26627737	HCT116	viability after 9 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-3.094962580448105	[545]	[25,9]	-9	hSpCas9	negative selection	1989860
95308053	95308076	7	-	26627737	HCT116	viability after 9 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	0.45793787195854524	[356]	[121,137]	3	hSpCas9	negative selection	1989861
95311539	95311562	7	+	26627737	HCT116	viability after 9 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	-2.5564752585124912	[338]	[25,6]	-9	hSpCas9	negative selection	1989862
95316748	95316771	7	-	26627737	HCT116	viability after 9 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.6984916452726793	[533]	[112,67]	-5	hSpCas9	negative selection	1989863
95318368	95318391	7	-	26627737	HCT116	viability after 9 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	1.4564745781603738	[751]	[435,641]	8	hSpCas9	negative selection	1989864
95324455	95324478	7	+	26627737	HCT116	viability after 9 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-1.359969237958999	[445]	[13,71]	-7	hSpCas9	negative selection	1989865
95302255	95302278	7	+	26627737	HCT116	viability after 12 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.1247076950255821	[242]	[113,183,122]	1	hSpCas9	negative selection	2072175
95308053	95308076	7	-	26627737	HCT116	viability after 12 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	0.3341214528234533	[188]	[148,102,120]	3	hSpCas9	negative selection	2072176
95311539	95311562	7	+	26627737	HCT116	viability after 12 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	-0.2581179391548032	[136]	[13,73,96]	-3	hSpCas9	negative selection	2072177
95316748	95316771	7	-	26627737	HCT116	viability after 12 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-1.2929402886181744	[226]	[61,11,69]	-8	hSpCas9	negative selection	2072178
95318368	95318391	7	-	26627737	HCT116	viability after 12 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.4387404277813403	[261]	[122,249,193]	4	hSpCas9	negative selection	2072179
95324455	95324478	7	+	26627737	HCT116	viability after 12 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-1.0012867540857733	[455]	[117,148,92]	-8	hSpCas9	negative selection	2072180
95302255	95302278	7	+	26627737	HCT116	viability after 15 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.43758992366363486	[242]	[222,146,200]	4	hSpCas9	negative selection	2154490
95308053	95308076	7	-	26627737	HCT116	viability after 15 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-0.038284052743385755	[188]	[139,52,127]	0	hSpCas9	negative selection	2154491
95311539	95311562	7	+	26627737	HCT116	viability after 15 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	-0.7276007049373758	[136]	[43,40,56]	-6	hSpCas9	negative selection	2154492
95316748	95316771	7	-	26627737	HCT116	viability after 15 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.5905927030200315	[226]	[153,33,79]	-6	hSpCas9	negative selection	2154493
95318368	95318391	7	-	26627737	HCT116	viability after 15 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	1.0852875811776677	[261]	[265,341,342]	8	hSpCas9	negative selection	2154494
95324455	95324478	7	+	26627737	HCT116	viability after 15 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-1.1911264817054197	[455]	[119,132,91]	-8	hSpCas9	negative selection	2154495
95302255	95302278	7	+	26627737	HCT116	viability after 18 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.888363778990876	[242]	[305,192,151]	7	hSpCas9	negative selection	2236805
95308053	95308076	7	-	26627737	HCT116	viability after 18 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	0.04626941723398259	[188]	[93,34,160]	0	hSpCas9	negative selection	2236806
95311539	95311562	7	+	26627737	HCT116	viability after 18 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.3030949986822219	[136]	[38,91,114]	2	hSpCas9	negative selection	2236807
95316748	95316771	7	-	26627737	HCT116	viability after 18 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.5602111652011563	[226]	[85,54,83]	-5	hSpCas9	negative selection	2236808
95318368	95318391	7	-	26627737	HCT116	viability after 18 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	1.2150383696699154	[261]	[226,279,379]	8	hSpCas9	negative selection	2236809
95324455	95324478	7	+	26627737	HCT116	viability after 18 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-1.4846069681463754	[455]	[85,52,99]	-8	hSpCas9	negative selection	2236810
95324680	95324703	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAGGAGCAAAATGGGACTTTTGG	PON1	ENSG00000005421	-0.45730118651308294	[78,194]	[12,30]	-2	dCas9-VP64	positive selection	2384020
95324641	95324664	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCGGTCAGCCCCCACCGCAGG	PON1	ENSG00000005421	0.40617176139714606	[118,74]	[26,28]	1	dCas9-VP64	positive selection	2384021
95324680	95324703	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAGGAGCAAAATGGGACTTTTGG	PON1	ENSG00000005421	0.36566083559553875	[147,125]	[36,75]	3	dCas9-VP64	positive selection	2479275
95324641	95324664	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCGGTCAGCCCCCACCGCAGG	PON1	ENSG00000005421	-1.0440160109335586	[83,112]	[15,13]	-8	dCas9-VP64	positive selection	2479276
95318368	95318391	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.4427818133482725	[4,4]	[4,6]	8	hSpCas9	positive selection	3012586
95324431	95324454	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	0.46660071263924396	[3,3]	[3,4]	8	hSpCas9	positive selection	3012587
95318368	95318391	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.11559567433095874	[4,4]	[4,2]	2	hSpCas9	positive selection	3080444
95324431	95324454	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.30793236327207746	[3,3]	[3,0]	-5	hSpCas9	positive selection	3080445
95316769	95316792		-	24336571	A375	resistance to PLX after 7 days	AGAAACTGGCTCTGAAGACTTGG	PON1	ENSG00000005421	-0.24344478207836728	[8,6]	[6,6]	-7	hSpCas9	positive selection	3136857
95311557	95311580		-	24336571	A375	resistance to PLX after 7 days	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.16016313642879398	[16,13]	[13,13]	-5	hSpCas9	positive selection	3136858
95316769	95316792		-	24336571	A375	resistance to PLX after 14 days	AGAAACTGGCTCTGAAGACTTGG	PON1	ENSG00000005421	0.9497168484098806	[4,4]	[4,3]	7	hSpCas9	positive selection	3194650
95311557	95311580		-	24336571	A375	resistance to PLX after 14 days	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.9925109651337356	[14,16]	[2,3]	-9	hSpCas9	positive selection	3194651
95316769	95316792		-	24336571	A375	viability after 7 days	AGAAACTGGCTCTGAAGACTTGG	PON1	ENSG00000005421	0.5807820488314269	[5]	[8,6]	8	hSpCas9	negative selection	3252443
95311557	95311580		-	24336571	A375	viability after 7 days	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.024036419240490603	[16]	[16,13]	0	hSpCas9	negative selection	3252444
95316769	95316792		-	24336571	A375	viability after 14 days	AGAAACTGGCTCTGAAGACTTGG	PON1	ENSG00000005421	-0.05285206956337696	[5]	[4,4]	0	hSpCas9	negative selection	3310236
95311557	95311580		-	24336571	A375	viability after 14 days	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	0.04653850568066431	[16]	[14,16]	0	hSpCas9	negative selection	3310237
95306341	95306364	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	0.5991147286940403	[100,100]	[0,0]	3	hSpCas9	positive selection	3386798
95311557	95311580	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.9025451253325543	[285,285]	[0,0]	-6	hSpCas9	positive selection	3386799
95316738	95316761	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	-0.5944228299702223	[230,230]	[0,0]	-4	hSpCas9	positive selection	3386800
95318368	95318391	7	-	26780180	HT29	viability (Avana library 4 designs)	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.645092895578562	[]	[]	2	hSpCas9	negative selection	3450703
95311542	95311565	7	+	26780180	HT29	viability (Avana library 4 designs)	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.875159788265778	[]	[]	3	hSpCas9	negative selection	3450704
95324455	95324478	7	+	26780180	HT29	viability (Avana library 4 designs)	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.703436465607169	[]	[]	2	hSpCas9	negative selection	3450705
95324430	95324453	7	+	26780180	HT29	viability (Avana library 4 designs)	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	1.38920936789478	[]	[]	5	hSpCas9	negative selection	3450706
95324455	95324478	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-1.90344172432928	[]	[]	-2	hSpCas9	negative selection	3546077
95311542	95311565	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	4.70234469552886	[]	[]	7	hSpCas9	negative selection	3546078
95318368	95318391	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	2.10788551868081	[]	[]	3	hSpCas9	negative selection	3546079
95324430	95324453	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	2.10709590109092	[]	[]	3	hSpCas9	negative selection	3546080
95324455	95324478	7	+	26780180	A375	viability (Avana lentiGuide)	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.967072404723605	[]	[]	1	hSpCas9	negative selection	3654736
95311542	95311565	7	+	26780180	A375	viability (Avana lentiGuide)	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.446342429842837	[]	[]	0	hSpCas9	negative selection	3654737
95318368	95318391	7	-	26780180	A375	viability (Avana lentiGuide)	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	2.41569651058181	[]	[]	2	hSpCas9	negative selection	3654738
95324430	95324453	7	+	26780180	A375	viability (Avana lentiGuide)	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	8.94530311880843	[]	[]	6	hSpCas9	negative selection	3654739
95324455	95324478	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.21830096148053743	[4]	[3,4]	-3	hSpCas9	positive selection	3763395
95311542	95311565	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.38919286244951684	[4]	[6,5]	9	hSpCas9	positive selection	3763396
95318368	95318391	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.08120463271561779	[6]	[7,5]	2	hSpCas9	positive selection	3763397
95324430	95324453	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	0.04039286670368282	[4]	[5,3]	1	hSpCas9	positive selection	3763398
95324455	95324478	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.14004671215691236	[5]	[4,3]	-2	hSpCas9	positive selection	3872002
95311542	95311565	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	-0.7132256330835209	[5]	[4,0]	-7	hSpCas9	positive selection	3872003
95318368	95318391	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.04023066360970004	[6]	[5,5]	0	hSpCas9	positive selection	3872004
95324430	95324453	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.4185004699678715	[5]	[4,2]	-5	hSpCas9	positive selection	3872005
95318368	95318391	7	-	26780180	A375	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	1.39397335810412	[]	[]	7	hSpCas9	negative selection	3982838
95311557	95311580	7	-	26780180	A375	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	1.92346302869522	[]	[]	9	hSpCas9	negative selection	3982839
95311539	95311562	7	+	26780180	A375	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.822118442370048	[]	[]	3	hSpCas9	negative selection	3982840
95316738	95316761	7	+	26780180	A375	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	1.25981359610953	[]	[]	6	hSpCas9	negative selection	3982841
95318353	95318376	7	+	26780180	A375	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.537007120275906	[]	[]	1	hSpCas9	negative selection	3982842
95306341	95306364	7	-	26780180	A375	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	1.56485996494442	[]	[]	8	hSpCas9	negative selection	3982843
95318368	95318391	7	-	26780180	HT29	viability (GeCKOv2 library)	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	1.0555035759599	[]	[]	5	hSpCas9	negative selection	4090804
95311557	95311580	7	-	26780180	HT29	viability (GeCKOv2 library)	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	1.65253560264103	[]	[]	8	hSpCas9	negative selection	4090805
95311539	95311562	7	+	26780180	HT29	viability (GeCKOv2 library)	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.459287652533197	[]	[]	1	hSpCas9	negative selection	4090806
95316738	95316761	7	+	26780180	HT29	viability (GeCKOv2 library)	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	1.20058325994762	[]	[]	6	hSpCas9	negative selection	4090807
95318353	95318376	7	+	26780180	HT29	viability (GeCKOv2 library)	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.677596041635164	[]	[]	2	hSpCas9	negative selection	4090808
95306341	95306364	7	-	26780180	HT29	viability (GeCKOv2 library)	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	1.58682055719115	[]	[]	8	hSpCas9	negative selection	4090809
95316769	95316792	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGAAACTGGCTCTGAAGACTTGG	PON1	ENSG00000005421	0.010918587275893232	[2]	[0,1]	0	hSpCas9	positive selection	4161920
95311557	95311580	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.05261508995600048	[3]	[2,1]	-1	hSpCas9	positive selection	4161921
95316769	95316792	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGAAACTGGCTCTGAAGACTTGG	PON1	ENSG00000005421	0.3800698868213629	[2]	[0,0,3,0]	3	hSpCas9	positive selection	4225942
95311557	95311580	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	0.3757037231031878	[4]	[3,4,3,0]	3	hSpCas9	positive selection	4225943
95318368	95318391	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.01057405198242553	[3]	[3,1]	0	hSpCas9	positive selection	4291327
95318353	95318376	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.5314267424515141	[3]	[4,4]	9	hSpCas9	positive selection	4291328
95311539	95311562	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.26821482787722606	[4]	[4,3]	5	hSpCas9	positive selection	4291329
95306341	95306364	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	0.07791360305298159	[2]	[2,1]	1	hSpCas9	positive selection	4355576
95311557	95311580	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	0.11003211382662018	[3]	[2,3]	2	hSpCas9	positive selection	4355577
95316738	95316761	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.3570759035938556	[3]	[3,3]	7	hSpCas9	positive selection	4355578
95308103	95308125	7	-	27760321	OCIAML3	viability	GATGTATTTGGGTTTAGCGTGG	PON1	ENSG00000005421	0.06671681316450613	[446,419]	[294,433]	0	hSpCas9	negative selection	4429414
95311540	95311562	7	+	27760321	OCIAML3	viability	ATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.112634434258293	[738,615]	[474,694]	1	hSpCas9	negative selection	4429415
95315391	95315413	7	-	27760321	OCIAML3	viability	GATCCAACAGTGTTGGAATTGG	PON1	ENSG00000005421	0.6614222412930899	[242,215]	[236,343]	7	hSpCas9	negative selection	4429416
95315444	95315466	7	-	27760321	OCIAML3	viability	GCTTCAACCCCAACAGTCCTGG	PON1	ENSG00000005421	0.8548042521601962	[645,557]	[622,1143]	8	hSpCas9	negative selection	4429417
95316748	95316770	7	-	27760321	OCIAML3	viability	GAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.10112120630700847	[367,348]	[261,351]	1	hSpCas9	negative selection	4429418
95308103	95308125	7	-	27760321	OCIAML2	viability	GATGTATTTGGGTTTAGCGTGG	PON1	ENSG00000005421	0.28666371230232457	[446,419]	[311,580]	4	hSpCas9	negative selection	4512877
95311540	95311562	7	+	27760321	OCIAML2	viability	ATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.4262229106730673	[738,615]	[656,833]	6	hSpCas9	negative selection	4512878
95315391	95315413	7	-	27760321	OCIAML2	viability	GATCCAACAGTGTTGGAATTGG	PON1	ENSG00000005421	-0.0045353193885393495	[242,215]	[173,198]	0	hSpCas9	negative selection	4512879
95315444	95315466	7	-	27760321	OCIAML2	viability	GCTTCAACCCCAACAGTCCTGG	PON1	ENSG00000005421	0.36800238042979766	[645,557]	[552,723]	5	hSpCas9	negative selection	4512880
95316748	95316770	7	-	27760321	OCIAML2	viability	GAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.27381007143033564	[367,348]	[218,267]	-3	hSpCas9	negative selection	4512881
95308103	95308125	7	-	27760321	MV411	viability	GATGTATTTGGGTTTAGCGTGG	PON1	ENSG00000005421	0.3689644833613945	[446,419]	[252,544]	2	hSpCas9	negative selection	4596340
95311540	95311562	7	+	27760321	MV411	viability	ATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.7336704074641556	[738,615]	[667,848]	5	hSpCas9	negative selection	4596341
95315391	95315413	7	-	27760321	MV411	viability	GATCCAACAGTGTTGGAATTGG	PON1	ENSG00000005421	0.15329921722651818	[242,215]	[126,229]	1	hSpCas9	negative selection	4596342
95315444	95315466	7	-	27760321	MV411	viability	GCTTCAACCCCAACAGTCCTGG	PON1	ENSG00000005421	0.09668888748246135	[645,557]	[475,344]	0	hSpCas9	negative selection	4596343
95316748	95316770	7	-	27760321	MV411	viability	GAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-2.1225314155986874	[367,348]	[39,75]	-8	hSpCas9	negative selection	4596344
95308103	95308125	7	-	27760321	HL60	viability	GATGTATTTGGGTTTAGCGTGG	PON1	ENSG00000005421	0.43303774079219387	[446,419]	[442,515]	5	hSpCas9	negative selection	4679803
95311540	95311562	7	+	27760321	HL60	viability	ATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.3230972217389131	[738,615]	[588,795]	4	hSpCas9	negative selection	4679804
95315391	95315413	7	-	27760321	HL60	viability	GATCCAACAGTGTTGGAATTGG	PON1	ENSG00000005421	0.5304475537614552	[242,215]	[298,239]	6	hSpCas9	negative selection	4679805
95315444	95315466	7	-	27760321	HL60	viability	GCTTCAACCCCAACAGTCCTGG	PON1	ENSG00000005421	0.5836877755514365	[645,557]	[717,752]	7	hSpCas9	negative selection	4679806
95316748	95316770	7	-	27760321	HL60	viability	GAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.6056355619775542	[367,348]	[131,256]	-6	hSpCas9	negative selection	4679807
95308103	95308125	7	-	27760321	HT1080	viability	GATGTATTTGGGTTTAGCGTGG	PON1	ENSG00000005421	0.12443545068229436	[419,327]	[107,221]	0	hSpCas9	negative selection	4763266
95311540	95311562	7	+	27760321	HT1080	viability	ATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.27018977759995977	[615,480]	[147,389]	1	hSpCas9	negative selection	4763267
95315391	95315413	7	-	27760321	HT1080	viability	GATCCAACAGTGTTGGAATTGG	PON1	ENSG00000005421	-0.5135115094060838	[215,168]	[47,59]	-2	hSpCas9	negative selection	4763268
95315444	95315466	7	-	27760321	HT1080	viability	GCTTCAACCCCAACAGTCCTGG	PON1	ENSG00000005421	0.8230580136655086	[557,435]	[598,77]	4	hSpCas9	negative selection	4763269
95316748	95316770	7	-	27760321	HT1080	viability	GAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.8908984474018127	[348,272]	[41,93]	-4	hSpCas9	negative selection	4763270
95308103	95308125	7	-	27760321	HT29	viability after 7 days	GATGTATTTGGGTTTAGCGTGG	PON1	ENSG00000005421	-0.4703813558661424	[419,327]	[352,290,395]	-6	hSpCas9	negative selection	4846729
95311540	95311562	7	+	27760321	HT29	viability after 7 days	ATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	-0.15948622864268097	[615,480]	[733,669,507]	-2	hSpCas9	negative selection	4846730
95315391	95315413	7	-	27760321	HT29	viability after 7 days	GATCCAACAGTGTTGGAATTGG	PON1	ENSG00000005421	0.3033478939615687	[215,168]	[416,245,269]	4	hSpCas9	negative selection	4846731
95315444	95315466	7	-	27760321	HT29	viability after 7 days	GCTTCAACCCCAACAGTCCTGG	PON1	ENSG00000005421	-0.09392749751820817	[557,435]	[509,585,683]	-1	hSpCas9	negative selection	4846732
95316748	95316770	7	-	27760321	HT29	viability after 7 days	GAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.8582159710329367	[348,272]	[245,162,254]	-8	hSpCas9	negative selection	4846733
95308103	95308125	7	-	27760321	HT29	viability after 25 days	GATGTATTTGGGTTTAGCGTGG	PON1	ENSG00000005421	-0.04426825425151555	[419,327]	[227,548,484]	0	hSpCas9	negative selection	4930192
95311540	95311562	7	+	27760321	HT29	viability after 25 days	ATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.410887739655711	[615,480]	[684,871,964]	4	hSpCas9	negative selection	4930193
95315391	95315413	7	-	27760321	HT29	viability after 25 days	GATCCAACAGTGTTGGAATTGG	PON1	ENSG00000005421	-0.38227873267968104	[215,168]	[90,182,244]	-4	hSpCas9	negative selection	4930194
95315444	95315466	7	-	27760321	HT29	viability after 25 days	GCTTCAACCCCAACAGTCCTGG	PON1	ENSG00000005421	0.3788517465839798	[557,435]	[562,878,788]	4	hSpCas9	negative selection	4930195
95316748	95316770	7	-	27760321	HT29	viability after 25 days	GAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.24501074187629618	[348,272]	[209,205,510]	-3	hSpCas9	negative selection	4930196
95308103	95308125	7	-	27760321	HT29	viability after 22 days	GATGTATTTGGGTTTAGCGTGG	PON1	ENSG00000005421	-0.15583078447076346	[419,327]	[310,508,345]	-1	hSpCas9	negative selection	5013655
95311540	95311562	7	+	27760321	HT29	viability after 22 days	ATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.23062238864476836	[615,480]	[791,669,768]	2	hSpCas9	negative selection	5013656
95315391	95315413	7	-	27760321	HT29	viability after 22 days	GATCCAACAGTGTTGGAATTGG	PON1	ENSG00000005421	0.2595394674952193	[215,168]	[321,189,285]	2	hSpCas9	negative selection	5013657
95315444	95315466	7	-	27760321	HT29	viability after 22 days	GCTTCAACCCCAACAGTCCTGG	PON1	ENSG00000005421	0.3021290099322853	[557,435]	[589,677,861]	3	hSpCas9	negative selection	5013658
95316748	95316770	7	-	27760321	HT29	viability after 22 days	GAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.14992361325484377	[348,272]	[337,192,441]	-1	hSpCas9	negative selection	5013659
95308103	95308125	7	-	27760321	HT29	viability after 19 days	GATGTATTTGGGTTTAGCGTGG	PON1	ENSG00000005421	0.43449868160846467	[419,327]	[470,575,671]	4	hSpCas9	negative selection	5097118
95311540	95311562	7	+	27760321	HT29	viability after 19 days	ATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.19407217908298524	[615,480]	[1155,609,442]	1	hSpCas9	negative selection	5097119
95315391	95315413	7	-	27760321	HT29	viability after 19 days	GATCCAACAGTGTTGGAATTGG	PON1	ENSG00000005421	0.66218617277381	[215,168]	[154,417,447]	6	hSpCas9	negative selection	5097120
95315444	95315466	7	-	27760321	HT29	viability after 19 days	GCTTCAACCCCAACAGTCCTGG	PON1	ENSG00000005421	0.10995452854854737	[557,435]	[842,594,432]	1	hSpCas9	negative selection	5097121
95316748	95316770	7	-	27760321	HT29	viability after 19 days	GAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.360649916393474	[348,272]	[261,614,471]	3	hSpCas9	negative selection	5097122
95308103	95308125	7	-	27760321	HT29	viability after 16 days	GATGTATTTGGGTTTAGCGTGG	PON1	ENSG00000005421	0.2720702509862138	[419,327]	[389,654,455]	3	hSpCas9	negative selection	5180581
95311540	95311562	7	+	27760321	HT29	viability after 16 days	ATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.28360325426914124	[615,480]	[612,907,702]	3	hSpCas9	negative selection	5180582
95315391	95315413	7	-	27760321	HT29	viability after 16 days	GATCCAACAGTGTTGGAATTGG	PON1	ENSG00000005421	0.36994349279772665	[215,168]	[361,199,282]	4	hSpCas9	negative selection	5180583
95315444	95315466	7	-	27760321	HT29	viability after 16 days	GCTTCAACCCCAACAGTCCTGG	PON1	ENSG00000005421	0.3115759559358364	[557,435]	[703,904,456]	3	hSpCas9	negative selection	5180584
95316748	95316770	7	-	27760321	HT29	viability after 16 days	GAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.19999777444107658	[348,272]	[254,274,374]	-2	hSpCas9	negative selection	5180585
95308103	95308125	7	-	27760321	HT29	viability after 13 days	GATGTATTTGGGTTTAGCGTGG	PON1	ENSG00000005421	0.06726811607732322	[419,327]	[386,472,500]	0	hSpCas9	negative selection	5264044
95311540	95311562	7	+	27760321	HT29	viability after 13 days	ATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.3208055211378408	[615,480]	[1183,517,687]	4	hSpCas9	negative selection	5264045
95315391	95315413	7	-	27760321	HT29	viability after 13 days	GATCCAACAGTGTTGGAATTGG	PON1	ENSG00000005421	-0.005606349598222593	[215,168]	[233,135,292]	0	hSpCas9	negative selection	5264046
95315444	95315466	7	-	27760321	HT29	viability after 13 days	GCTTCAACCCCAACAGTCCTGG	PON1	ENSG00000005421	0.2970138567439229	[557,435]	[770,815,547]	4	hSpCas9	negative selection	5264047
95316748	95316770	7	-	27760321	HT29	viability after 13 days	GAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.28413280052896256	[348,272]	[242,194,441]	-3	hSpCas9	negative selection	5264048
95308103	95308125	7	-	27760321	HT29	viability after 10 days	GATGTATTTGGGTTTAGCGTGG	PON1	ENSG00000005421	-0.35164383730491405	[419,327]	[426,381,290]	-4	hSpCas9	negative selection	5347507
95311540	95311562	7	+	27760321	HT29	viability after 10 days	ATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.047791748286355906	[615,480]	[679,927,525]	0	hSpCas9	negative selection	5347508
95315391	95315413	7	-	27760321	HT29	viability after 10 days	GATCCAACAGTGTTGGAATTGG	PON1	ENSG00000005421	-0.14363490423724512	[215,168]	[355,79,212]	-2	hSpCas9	negative selection	5347509
95315444	95315466	7	-	27760321	HT29	viability after 10 days	GCTTCAACCCCAACAGTCCTGG	PON1	ENSG00000005421	0.19858164380677434	[557,435]	[763,661,708]	2	hSpCas9	negative selection	5347510
95316748	95316770	7	-	27760321	HT29	viability after 10 days	GAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.2510099266960641	[348,272]	[276,248,447]	-3	hSpCas9	negative selection	5347511
95308103	95308125	7	-	27760321	MOLM13	viability	GATGTATTTGGGTTTAGCGTGG	PON1	ENSG00000005421	0.4053360850093383	[446,419]	[274,365]	3	hSpCas9	negative selection	5430970
95311540	95311562	7	+	27760321	MOLM13	viability	ATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.8211424969381456	[738,615]	[429,878]	6	hSpCas9	negative selection	5430971
95315391	95315413	7	-	27760321	MOLM13	viability	GATCCAACAGTGTTGGAATTGG	PON1	ENSG00000005421	0.7633623251148578	[242,215]	[320,132]	5	hSpCas9	negative selection	5430972
95315444	95315466	7	-	27760321	MOLM13	viability	GCTTCAACCCCAACAGTCCTGG	PON1	ENSG00000005421	1.1232450739148419	[645,557]	[463,970]	7	hSpCas9	negative selection	5430973
95316748	95316770	7	-	27760321	MOLM13	viability	GAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.9654676126572146	[367,348]	[537,273]	7	hSpCas9	negative selection	5430974
95318368	95318391	7	-	27260156	BXPC3	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.2230667278127122	[730]	[594,622,634,785]	-5	hSpCas9	negative selection	5563787
95318353	95318376	7	+	27260156	BXPC3	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.047321565010274735	[961]	[1088,856,1138,1076]	1	hSpCas9	negative selection	5563788
95311539	95311562	7	+	27260156	BXPC3	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.4204065344331567	[996]	[1205,1425,1287,1705]	8	hSpCas9	negative selection	5563789
95306341	95306364	7	-	27260156	BXPC3	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.004642879610699979	[285]	[243,249,317,399]	0	hSpCas9	negative selection	5628036
95311557	95311580	7	-	27260156	BXPC3	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.24336510298459468	[715]	[639,462,690,756]	-5	hSpCas9	negative selection	5628037
95316738	95316761	7	+	27260156	BXPC3	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.08659810489697828	[563]	[526,623,597,780]	2	hSpCas9	negative selection	5628038
95318368	95318391	7	-	27260156	A673	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.11077992160778449	[730]	[764,779,980,711]	-3	hSpCas9	negative selection	5685038
95318353	95318376	7	+	27260156	A673	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.1277962969317339	[961]	[1386,1238,1153,1282]	3	hSpCas9	negative selection	5685039
95311539	95311562	7	+	27260156	A673	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.31369910207524154	[996]	[1526,1537,1466,1415]	7	hSpCas9	negative selection	5685040
95306341	95306364	7	-	27260156	A673	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.5093503262455046	[285]	[218,240,213,290]	-8	hSpCas9	negative selection	5749287
95311557	95311580	7	-	27260156	A673	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.43668796378338626	[715]	[678,727,534,598]	-8	hSpCas9	negative selection	5749288
95316738	95316761	7	+	27260156	A673	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	-0.036776542743641255	[563]	[627,642,655,711]	-1	hSpCas9	negative selection	5749289
95318368	95318391	7	-	27260156	A375	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.2148311169367238	[730]	[655,1112,729,518]	-3	hSpCas9	negative selection	5806289
95318353	95318376	7	+	27260156	A375	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.12417759448833876	[961]	[1027,1446,1240,1208]	1	hSpCas9	negative selection	5806290
95311539	95311562	7	+	27260156	A375	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.4994722782706851	[996]	[1954,1739,1420,1495]	7	hSpCas9	negative selection	5806291
95306341	95306364	7	-	27260156	A375	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.4621905860138611	[285]	[173,326,243,235]	-6	hSpCas9	negative selection	5870538
95311557	95311580	7	-	27260156	A375	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.19795174485117006	[715]	[809,1018,485,648]	-3	hSpCas9	negative selection	5870539
95316738	95316761	7	+	27260156	A375	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.22957551209835275	[563]	[777,938,650,744]	3	hSpCas9	negative selection	5870540
95318368	95318391	7	-	27260156	COLO741	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.07560840894325316	[730]	[1211,892,872]	1	hSpCas9	negative selection	5927540
95318353	95318376	7	+	27260156	COLO741	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.11028667490915955	[961]	[1620,1140,1245]	2	hSpCas9	negative selection	5927541
95311539	95311562	7	+	27260156	COLO741	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.3499349825192066	[996]	[1682,1621,1570]	7	hSpCas9	negative selection	5927542
95306341	95306364	7	-	27260156	COLO741	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.7996622761275369	[285]	[231,228,172]	-9	hSpCas9	negative selection	5991789
95311557	95311580	7	-	27260156	COLO741	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.46171666507707765	[715]	[828,706,482]	-7	hSpCas9	negative selection	5991790
95316738	95316761	7	+	27260156	COLO741	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.20682043939467193	[563]	[930,606,953]	4	hSpCas9	negative selection	5991791
95318368	95318391	7	-	27260156	CAL120	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.025109292418518225	[730]	[1122,701,890]	0	hSpCas9	negative selection	6048791
95318353	95318376	7	+	27260156	CAL120	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.22721281497873136	[961]	[1500,1634,1087]	3	hSpCas9	negative selection	6048792
95311539	95311562	7	+	27260156	CAL120	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.2538690183557326	[996]	[1710,1152,1605]	4	hSpCas9	negative selection	6048793
95306341	95306364	7	-	27260156	CAL120	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.31918675440750044	[285]	[349,263,251]	-5	hSpCas9	negative selection	6113040
95311557	95311580	7	-	27260156	CAL120	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	0.15539815596969608	[715]	[951,776,1236]	2	hSpCas9	negative selection	6113041
95316738	95316761	7	+	27260156	CAL120	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.2125731380884116	[563]	[730,1047,650]	3	hSpCas9	negative selection	6113042
95318368	95318391	7	-	27260156	CADOES1	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.5572721476194805	[730]	[535,449,448,410]	-7	hSpCas9	negative selection	6170042
95318353	95318376	7	+	27260156	CADOES1	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.23033231084054506	[961]	[1401,1037,899,849]	4	hSpCas9	negative selection	6170043
95311539	95311562	7	+	27260156	CADOES1	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.4254063483005912	[996]	[1271,1294,1401,1002]	7	hSpCas9	negative selection	6170044
95306341	95306364	7	-	27260156	CADOES1	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.5561068112120471	[285]	[123,198,240,158]	-7	hSpCas9	negative selection	6234291
95311557	95311580	7	-	27260156	CADOES1	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.23230624073781148	[715]	[406,471,838,548]	-4	hSpCas9	negative selection	6234292
95316738	95316761	7	+	27260156	CADOES1	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	-0.030101092849171895	[563]	[538,526,496,490]	0	hSpCas9	negative selection	6234293
95318368	95318391	7	-	27260156	EWS502	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.11400655065867393	[730]	[670,630,846,720]	-2	hSpCas9	negative selection	6291293
95318353	95318376	7	+	27260156	EWS502	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.04755752038936345	[961]	[1068,1021,1122,989]	0	hSpCas9	negative selection	6291294
95311539	95311562	7	+	27260156	EWS502	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.3833020007781436	[996]	[1097,1420,1497,1531]	6	hSpCas9	negative selection	6291295
95306341	95306364	7	-	27260156	EWS502	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.27870020503740855	[285]	[401,170,163,243]	-5	hSpCas9	negative selection	6355542
95311557	95311580	7	-	27260156	EWS502	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.4488861978300246	[715]	[312,496,596,867]	-6	hSpCas9	negative selection	6355543
95316738	95316761	7	+	27260156	EWS502	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.0021265926239893984	[563]	[596,592,588,612]	0	hSpCas9	negative selection	6355544
95318368	95318391	7	-	27260156	EW8	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.24478704816446795	[730]	[590,414,457,550]	-4	hSpCas9	negative selection	6412544
95318353	95318376	7	+	27260156	EW8	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	-0.0819424079213058	[961]	[679,691,726,839]	-1	hSpCas9	negative selection	6412545
95311539	95311562	7	+	27260156	EW8	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.3956967052566065	[996]	[1252,1057,943,1034]	7	hSpCas9	negative selection	6412546
95306341	95306364	7	-	27260156	EW8	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.2583842775490661	[285]	[164,313,194,97]	-5	hSpCas9	negative selection	6476793
95311557	95311580	7	-	27260156	EW8	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.2055052616338639	[715]	[563,549,320,613]	-4	hSpCas9	negative selection	6476794
95316738	95316761	7	+	27260156	EW8	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	-0.04691051097794424	[563]	[562,373,337,523]	-1	hSpCas9	negative selection	6476795
95318368	95318391	7	-	27260156	CORL105	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.16198653799604407	[730]	[717,742,934,688]	-3	hSpCas9	negative selection	6533795
95318353	95318376	7	+	27260156	CORL105	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.07371127567394087	[961]	[1014,1308,1259,1159]	1	hSpCas9	negative selection	6533796
95311539	95311562	7	+	27260156	CORL105	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.483952697427555	[996]	[1912,1457,1879,1330]	8	hSpCas9	negative selection	6533797
95306341	95306364	7	-	27260156	CORL105	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.5323081829427909	[285]	[266,191,231,236]	-7	hSpCas9	negative selection	6598044
95311557	95311580	7	-	27260156	CORL105	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.20713466108899137	[715]	[734,624,931,646]	-4	hSpCas9	negative selection	6598045
95316738	95316761	7	+	27260156	CORL105	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.3472656789908811	[563]	[681,847,1012,837]	6	hSpCas9	negative selection	6598046
95318368	95318391	7	-	27260156	HS294T	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.5151795585071629	[730]	[124,164,253,265]	-6	hSpCas9	negative selection	6655046
95318353	95318376	7	+	27260156	HS294T	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.02112508438671079	[961]	[263,478,330,454]	0	hSpCas9	negative selection	6655047
95311539	95311562	7	+	27260156	HS294T	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.5002465700238679	[996]	[348,529,613,737]	6	hSpCas9	negative selection	6655048
95306341	95306364	7	-	27260156	HS294T	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	0.20581241557116003	[285]	[178,67,165,86]	3	hSpCas9	negative selection	6719295
95311557	95311580	7	-	27260156	HS294T	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.2713836828445087	[715]	[178,206,198,358]	-4	hSpCas9	negative selection	6719296
95316738	95316761	7	+	27260156	HS294T	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.37929770750878455	[563]	[314,330,228,247]	5	hSpCas9	negative selection	6719297
95318368	95318391	7	-	27260156	HCC44	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.19194262570449033	[730]	[795,595,630,869]	-3	hSpCas9	negative selection	6776297
95318353	95318376	7	+	27260156	HCC44	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.3713982498843853	[961]	[1756,1432,1441,1032]	6	hSpCas9	negative selection	6776298
95311539	95311562	7	+	27260156	HCC44	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.5801522287681768	[996]	[2026,1525,1601,1615]	8	hSpCas9	negative selection	6776299
95306341	95306364	7	-	27260156	HCC44	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.34161728505048905	[285]	[299,216,267,245]	-5	hSpCas9	negative selection	6840546
95311557	95311580	7	-	27260156	HCC44	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.3015257250377239	[715]	[597,564,904,606]	-5	hSpCas9	negative selection	6840547
95316738	95316761	7	+	27260156	HCC44	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.27988970911864286	[563]	[1201,514,785,669]	4	hSpCas9	negative selection	6840548
95318368	95318391	7	-	27260156	G402	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.031779332585005426	[730]	[722,1040,542,1153]	0	hSpCas9	negative selection	6897548
95318353	95318376	7	+	27260156	G402	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	-0.008813808944396317	[961]	[1606,1377,1029,743]	0	hSpCas9	negative selection	6897549
95311539	95311562	7	+	27260156	G402	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.2557706406589293	[996]	[1203,1565,1337,1656]	3	hSpCas9	negative selection	6897550
95306341	95306364	7	-	27260156	G402	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.6198649815754966	[285]	[281,299,223,118]	-6	hSpCas9	negative selection	6961797
95311557	95311580	7	-	27260156	G402	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.059988592587744693	[715]	[1109,1136,453,710]	0	hSpCas9	negative selection	6961798
95316738	95316761	7	+	27260156	G402	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.5119929291531661	[563]	[1173,889,491,1368]	6	hSpCas9	negative selection	6961799
95318368	95318391	7	-	27260156	L33	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.1676386512291696	[730]	[596,255,331,851]	-4	hSpCas9	negative selection	7018799
95318353	95318376	7	+	27260156	L33	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.14965993352989737	[961]	[1011,473,594,1152]	3	hSpCas9	negative selection	7018800
95311539	95311562	7	+	27260156	L33	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.0462985237618585	[996]	[979,364,729,1086]	1	hSpCas9	negative selection	7018801
95306341	95306364	7	-	27260156	L33	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.572250463524907	[285]	[207,82,108,184]	-8	hSpCas9	negative selection	7083048
95311557	95311580	7	-	27260156	L33	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.34092239539599806	[715]	[659,175,370,578]	-7	hSpCas9	negative selection	7083049
95316738	95316761	7	+	27260156	L33	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.1571938239338681	[563]	[666,270,365,603]	3	hSpCas9	negative selection	7083050
95318368	95318391	7	-	27260156	K562	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.06740716000778335	[730]	[644,627,533,663]	-1	hSpCas9	negative selection	7140050
95318353	95318376	7	+	27260156	K562	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.29423383260798586	[961]	[1107,1124,1213,776]	3	hSpCas9	negative selection	7140051
95311539	95311562	7	+	27260156	K562	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.3956868260815245	[996]	[1613,1309,829,964]	5	hSpCas9	negative selection	7140052
95306341	95306364	7	-	27260156	K562	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.05263745640833395	[285]	[431,119,240,198]	0	hSpCas9	negative selection	7204299
95311557	95311580	7	-	27260156	K562	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	0.08443296059362171	[715]	[1246,458,436,593]	1	hSpCas9	negative selection	7204300
95316738	95316761	7	+	27260156	K562	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.23469344029229394	[563]	[434,610,529,746]	3	hSpCas9	negative selection	7204301
95318368	95318391	7	-	27260156	HT29	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.270080744806666	[730]	[767,1132,469,621]	-5	hSpCas9	negative selection	7261301
95318353	95318376	7	+	27260156	HT29	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.24287111542611806	[961]	[1471,1224,1568,1266]	5	hSpCas9	negative selection	7261302
95311539	95311562	7	+	27260156	HT29	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.2926779256842671	[996]	[1596,1805,1366,1225]	6	hSpCas9	negative selection	7261303
95306341	95306364	7	-	27260156	HT29	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	0.06278437878958432	[285]	[484,392,392,209]	1	hSpCas9	negative selection	7325550
95311557	95311580	7	-	27260156	HT29	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.14211395908954783	[715]	[633,994,916,628]	-3	hSpCas9	negative selection	7325551
95316738	95316761	7	+	27260156	HT29	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.006309487857163898	[563]	[834,670,643,617]	0	hSpCas9	negative selection	7325552
95318368	95318391	7	-	27260156	MHHES1	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.14946632465728488	[730]	[619,978,774,616]	-3	hSpCas9	negative selection	7382552
95318353	95318376	7	+	27260156	MHHES1	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.21539805831250658	[961]	[1138,1485,1176,1217]	4	hSpCas9	negative selection	7382553
95311539	95311562	7	+	27260156	MHHES1	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.1601291611547877	[996]	[1468,1496,1048,1067]	3	hSpCas9	negative selection	7382554
95306341	95306364	7	-	27260156	MHHES1	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.39570650896169757	[285]	[141,353,194,273]	-6	hSpCas9	negative selection	7446801
95311557	95311580	7	-	27260156	MHHES1	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	0.06840633412953023	[715]	[616,1474,715,638]	1	hSpCas9	negative selection	7446802
95316738	95316761	7	+	27260156	MHHES1	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.02417535051501918	[563]	[873,650,427,642]	0	hSpCas9	negative selection	7446803
95318368	95318391	7	-	27260156	MEWO	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.10563384722660529	[730]	[691,712,793]	2	hSpCas9	negative selection	7503803
95318353	95318376	7	+	27260156	MEWO	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.1654132537965196	[961]	[1328,958,801]	3	hSpCas9	negative selection	7503804
95311539	95311562	7	+	27260156	MEWO	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.1357164707895393	[996]	[1208,972,927]	3	hSpCas9	negative selection	7503805
95306341	95306364	7	-	27260156	MEWO	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.4229433959326556	[285]	[180,219,193]	-7	hSpCas9	negative selection	7568052
95311557	95311580	7	-	27260156	MEWO	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.45718421670986337	[715]	[704,434,365]	-7	hSpCas9	negative selection	7568053
95316738	95316761	7	+	27260156	MEWO	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	-0.04549036156051775	[563]	[539,569,428]	-1	hSpCas9	negative selection	7568054
95318368	95318391	7	-	27260156	LNCAPCLONEFGC	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.03518800991995952	[730]	[666,435,969,572]	0	hSpCas9	negative selection	7625054
95318353	95318376	7	+	27260156	LNCAPCLONEFGC	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.23029571350570244	[961]	[963,977,1113,1049]	3	hSpCas9	negative selection	7625055
95311539	95311562	7	+	27260156	LNCAPCLONEFGC	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.5714274570210403	[996]	[1288,1312,1528,1266]	8	hSpCas9	negative selection	7625056
95306341	95306364	7	-	27260156	LNCAPCLONEFGC	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.09219193600895603	[285]	[217,175,364,235]	-1	hSpCas9	negative selection	7689303
95311557	95311580	7	-	27260156	LNCAPCLONEFGC	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.30699253943703025	[715]	[428,372,681,647]	-5	hSpCas9	negative selection	7689304
95316738	95316761	7	+	27260156	LNCAPCLONEFGC	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.036536368601249425	[563]	[507,632,410,519]	0	hSpCas9	negative selection	7689305
95318368	95318391	7	-	27260156	PANC0327	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.31024629328049114	[730]	[405,533,683,459]	-4	hSpCas9	negative selection	7746305
95318353	95318376	7	+	27260156	PANC0327	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.1409908992372988	[961]	[1007,1281,656,782]	2	hSpCas9	negative selection	7746306
95311539	95311562	7	+	27260156	PANC0327	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.8507074467253146	[996]	[1953,1488,1385,1601]	9	hSpCas9	negative selection	7746307
95306341	95306364	7	-	27260156	PANC0327	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.2885292797797132	[285]	[201,187,195,247]	-4	hSpCas9	negative selection	7810554
95311557	95311580	7	-	27260156	PANC0327	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	0.010499574380420817	[715]	[700,497,725,660]	0	hSpCas9	negative selection	7810555
95316738	95316761	7	+	27260156	PANC0327	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.290986255107508	[563]	[647,384,679,770]	4	hSpCas9	negative selection	7810556
95318368	95318391	7	-	27260156	NCIH2009	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.2203670603145279	[730]	[1196,643,854]	-3	hSpCas9	negative selection	7867556
95318353	95318376	7	+	27260156	NCIH2009	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	-0.12029498167773212	[961]	[1445,1176,1126]	-2	hSpCas9	negative selection	7867557
95311539	95311562	7	+	27260156	NCIH2009	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.2888809972230637	[996]	[1840,1533,1757]	4	hSpCas9	negative selection	7867558
95306341	95306364	7	-	27260156	NCIH2009	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.1093943485796055	[285]	[552,297,296]	-1	hSpCas9	negative selection	7931805
95311557	95311580	7	-	27260156	NCIH2009	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.2664675453104765	[715]	[860,740,898]	-4	hSpCas9	negative selection	7931806
95316738	95316761	7	+	27260156	NCIH2009	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.04209651194990727	[563]	[966,776,719]	0	hSpCas9	negative selection	7931807
95318368	95318391	7	-	27260156	NCIH1373	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.6992106918236194	[730]	[400,566,605,107]	-6	hSpCas9	negative selection	7988807
95318353	95318376	7	+	27260156	NCIH1373	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.2359460566898497	[961]	[1207,1170,1479,316]	2	hSpCas9	negative selection	7988808
95311539	95311562	7	+	27260156	NCIH1373	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.4527841889732396	[996]	[2394,1302,1275,337]	4	hSpCas9	negative selection	7988809
95306341	95306364	7	-	27260156	NCIH1373	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-1.1463129930727622	[285]	[229,181,134,8]	-8	hSpCas9	negative selection	8053056
95311557	95311580	7	-	27260156	NCIH1373	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.608514606635651	[715]	[628,615,394,122]	-6	hSpCas9	negative selection	8053057
95316738	95316761	7	+	27260156	NCIH1373	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.6240305180265395	[563]	[1514,668,1182,161]	6	hSpCas9	negative selection	8053058
95318368	95318391	7	-	27260156	PATU8902	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.5255218636327614	[730]	[950,500,711,646]	-5	hSpCas9	negative selection	8110058
95318353	95318376	7	+	27260156	PATU8902	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.2164052234125322	[961]	[1478,1475,1202,2228]	2	hSpCas9	negative selection	8110059
95311539	95311562	7	+	27260156	PATU8902	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.8383649940392468	[996]	[1596,2698,2176,3671]	8	hSpCas9	negative selection	8110060
95306341	95306364	7	-	27260156	PATU8902	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.3665942342969559	[285]	[370,100,213,605]	-4	hSpCas9	negative selection	8174307
95311557	95311580	7	-	27260156	PATU8902	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	0.24761610631663156	[715]	[1212,1586,770,1273]	2	hSpCas9	negative selection	8174308
95316738	95316761	7	+	27260156	PATU8902	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.6628774482005165	[563]	[1166,951,1679,1025]	7	hSpCas9	negative selection	8174309
95318368	95318391	7	-	27260156	PANC1	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.2438115446757882	[730]	[578,495,500,527]	-4	hSpCas9	negative selection	8231309
95318353	95318376	7	+	27260156	PANC1	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.2859577921662284	[961]	[916,1375,949,869]	4	hSpCas9	negative selection	8231310
95311539	95311562	7	+	27260156	PANC1	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.4819072262596842	[996]	[1219,1367,1297,953]	7	hSpCas9	negative selection	8231311
95306341	95306364	7	-	27260156	PANC1	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	0.029052736513529687	[285]	[282,268,224,227]	0	hSpCas9	negative selection	8295558
95311557	95311580	7	-	27260156	PANC1	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.19614003065390262	[715]	[494,729,443,512]	-3	hSpCas9	negative selection	8295559
95316738	95316761	7	+	27260156	PANC1	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.19205786098403016	[563]	[510,733,565,448]	3	hSpCas9	negative selection	8295560
95318368	95318391	7	-	27260156	PANC0813	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.09970377235315775	[730]	[820,821,1112,914]	1	hSpCas9	negative selection	8352560
95318353	95318376	7	+	27260156	PANC0813	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.24769663534423203	[961]	[1549,1303,1307,1227]	4	hSpCas9	negative selection	8352561
95311539	95311562	7	+	27260156	PANC0813	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.3864102906795224	[996]	[1559,1616,1435,1510]	6	hSpCas9	negative selection	8352562
95306341	95306364	7	-	27260156	PANC0813	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.6755562030800308	[285]	[250,239,221,135]	-7	hSpCas9	negative selection	8416809
95311557	95311580	7	-	27260156	PANC0813	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.34816644082427944	[715]	[556,744,649,678]	-5	hSpCas9	negative selection	8416810
95316738	95316761	7	+	27260156	PANC0813	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.3300185322269258	[563]	[659,1110,760,783]	5	hSpCas9	negative selection	8416811
95318368	95318391	7	-	27260156	RDES	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.09077232272362235	[730]	[697,669,653,1199]	-1	hSpCas9	negative selection	8473811
95318353	95318376	7	+	27260156	RDES	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	-0.24447280300365237	[961]	[814,972,845,1117]	-4	hSpCas9	negative selection	8473812
95311539	95311562	7	+	27260156	RDES	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.34088261198381997	[996]	[1087,1545,1537,1704]	5	hSpCas9	negative selection	8473813
95306341	95306364	7	-	27260156	RDES	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.5054254095877513	[285]	[230,160,333,198]	-7	hSpCas9	negative selection	8538060
95311557	95311580	7	-	27260156	RDES	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.43924880784168635	[715]	[525,613,596,703]	-6	hSpCas9	negative selection	8538061
95316738	95316761	7	+	27260156	RDES	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.16235957499489584	[563]	[535,697,731,1002]	2	hSpCas9	negative selection	8538062
95318368	95318391	7	-	27260156	PC3	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.13364569898052137	[730]	[554,653,1267,939]	3	hSpCas9	negative selection	8595062
95318353	95318376	7	+	27260156	PC3	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.2583252900083013	[961]	[788,1089,1884,1149]	5	hSpCas9	negative selection	8595063
95311539	95311562	7	+	27260156	PC3	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.4495439544093136	[996]	[1004,1222,2464,1167]	8	hSpCas9	negative selection	8595064
95306341	95306364	7	-	27260156	PC3	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.23286154495909173	[285]	[172,291,416,152]	-5	hSpCas9	negative selection	8659311
95311557	95311580	7	-	27260156	PC3	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.5697133461200943	[715]	[366,439,620,548]	-8	hSpCas9	negative selection	8659312
95316738	95316761	7	+	27260156	PC3	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	-0.053552742986123975	[563]	[352,433,994,598]	-1	hSpCas9	negative selection	8659313
95318368	95318391	7	-	27260156	PATU8988T	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.0022422288891257303	[730]	[601,681,886,639]	0	hSpCas9	negative selection	8716313
95318353	95318376	7	+	27260156	PATU8988T	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.30675252367921546	[961]	[1049,1189,1152,1214]	5	hSpCas9	negative selection	8716314
95311539	95311562	7	+	27260156	PATU8988T	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.5282726419788695	[996]	[1278,1312,1583,1369]	8	hSpCas9	negative selection	8716315
95306341	95306364	7	-	27260156	PATU8988T	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.5547691014481357	[285]	[176,251,113,218]	-7	hSpCas9	negative selection	8780562
95311557	95311580	7	-	27260156	PATU8988T	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.199087878468151	[715]	[394,794,519,729]	-3	hSpCas9	negative selection	8780563
95316738	95316761	7	+	27260156	PATU8988T	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	-0.3935493273487203	[563]	[357,403,465,430]	-6	hSpCas9	negative selection	8780564
95318368	95318391	7	-	27260156	T47D	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.05471051833831975	[730]	[798,803,797,881]	-1	hSpCas9	negative selection	8837564
95318353	95318376	7	+	27260156	T47D	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.16992662170417305	[961]	[1388,1148,1115,1405]	3	hSpCas9	negative selection	8837565
95311539	95311562	7	+	27260156	T47D	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.3669077768706377	[996]	[1534,1301,1555,1617]	7	hSpCas9	negative selection	8837566
95306341	95306364	7	-	27260156	T47D	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.17951875731651779	[285]	[381,162,300,343]	-4	hSpCas9	negative selection	8901813
95311557	95311580	7	-	27260156	T47D	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.33947512904130256	[715]	[522,611,748,757]	-6	hSpCas9	negative selection	8901814
95316738	95316761	7	+	27260156	T47D	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.07559452676780559	[563]	[758,644,636,734]	1	hSpCas9	negative selection	8901815
95318368	95318391	7	-	27260156	SU8686	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.23368188573335702	[730]	[776,712,830,1156]	4	hSpCas9	negative selection	8958815
95318353	95318376	7	+	27260156	SU8686	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.1745029608445936	[961]	[924,963,1270,1193]	3	hSpCas9	negative selection	8958816
95311539	95311562	7	+	27260156	SU8686	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.4282621304044003	[996]	[1246,1239,1350,1525]	7	hSpCas9	negative selection	8958817
95306341	95306364	7	-	27260156	SU8686	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.1528078249311572	[285]	[177,220,281,369]	-3	hSpCas9	negative selection	9023064
95311557	95311580	7	-	27260156	SU8686	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.32472025388407727	[715]	[553,493,608,627]	-5	hSpCas9	negative selection	9023065
95316738	95316761	7	+	27260156	SU8686	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.010008600680188662	[563]	[545,451,641,638]	0	hSpCas9	negative selection	9023066
95318368	95318391	7	-	27260156	SKES1	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.11800743270532721	[730]	[891,959,795,569]	2	hSpCas9	negative selection	9080066
95318353	95318376	7	+	27260156	SKES1	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	-0.01983246217683421	[961]	[1041,1065,873,835]	0	hSpCas9	negative selection	9080067
95311539	95311562	7	+	27260156	SKES1	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.43719732082473306	[996]	[1362,1418,1305,1300]	8	hSpCas9	negative selection	9080068
95306341	95306364	7	-	27260156	SKES1	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.8143809341715071	[285]	[236,131,211,81]	-9	hSpCas9	negative selection	9144315
95311557	95311580	7	-	27260156	SKES1	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.48062422410032796	[715]	[664,507,456,441]	-8	hSpCas9	negative selection	9144316
95316738	95316761	7	+	27260156	SKES1	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.03669068369271622	[563]	[779,473,558,512]	0	hSpCas9	negative selection	9144317
95318368	95318391	7	-	27260156	TOV112D	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.12474430951871673	[730]	[1409,727,509,583]	2	hSpCas9	negative selection	9201317
95318353	95318376	7	+	27260156	TOV112D	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	-0.0450093608968235	[961]	[1050,948,863,884]	-1	hSpCas9	negative selection	9201318
95311539	95311562	7	+	27260156	TOV112D	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.3659319371230525	[996]	[1615,1918,922,881]	7	hSpCas9	negative selection	9201319
95306341	95306364	7	-	27260156	TOV112D	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	0.07745167050569945	[285]	[350,541,127,251]	1	hSpCas9	negative selection	9265566
95311557	95311580	7	-	27260156	TOV112D	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.10005969903527356	[715]	[680,1178,430,514]	-2	hSpCas9	negative selection	9265567
95316738	95316761	7	+	27260156	TOV112D	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	-0.12320553475319279	[563]	[502,582,475,525]	-2	hSpCas9	negative selection	9265568
95318368	95318391	7	-	27260156	TC71	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	0.020791502142397666	[730]	[735,793,805,847]	0	hSpCas9	negative selection	9322568
95318353	95318376	7	+	27260156	TC71	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.0989873847543219	[961]	[1176,1076,984,1185]	2	hSpCas9	negative selection	9322569
95311539	95311562	7	+	27260156	TC71	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.2576537677385524	[996]	[1307,1331,1201,1269]	6	hSpCas9	negative selection	9322570
95306341	95306364	7	-	27260156	TC71	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.46945610986891717	[285]	[191,192,212,292]	-8	hSpCas9	negative selection	9386817
95311557	95311580	7	-	27260156	TC71	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.5398359288934315	[715]	[613,515,445,536]	-9	hSpCas9	negative selection	9386818
95316738	95316761	7	+	27260156	TC71	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	0.13402633311398482	[563]	[529,802,627,698]	3	hSpCas9	negative selection	9386819
95318368	95318391	7	-	27260156	TC32	viability	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.34096744424310943	[730]	[447,372,860,590]	-6	hSpCas9	negative selection	9443819
95318353	95318376	7	+	27260156	TC32	viability	GTTCTACGGGTTGTACCTCTCGG	PON1	ENSG00000005421	0.008625571787254982	[961]	[869,643,1102,1117]	0	hSpCas9	negative selection	9443820
95311539	95311562	7	+	27260156	TC32	viability	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.5160190626071368	[996]	[1366,934,1678,1516]	8	hSpCas9	negative selection	9443821
95306341	95306364	7	-	27260156	TC32	viability	TGTCTATATAGCTGAGTTGCTGG	PON1	ENSG00000005421	-0.5682147909164319	[285]	[213,104,232,196]	-8	hSpCas9	negative selection	9508068
95311557	95311580	7	-	27260156	TC32	viability	AGATAATGCCATGTACCTCCTGG	PON1	ENSG00000005421	-0.109594283681339	[715]	[552,498,897,609]	-2	hSpCas9	negative selection	9508069
95316738	95316761	7	+	27260156	TC32	viability	CTAATGAAAGCCAGTCCATTAGG	PON1	ENSG00000005421	-0.15232062898851365	[563]	[461,206,704,662]	-3	hSpCas9	negative selection	9508070
95302255	95302278	7	+	27869803	HPAFII	viability after 27 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-0.8435779462981418	[228]	[23,102,NaN]	-5	hSpCas9	negative selection	9600556
95308053	95308076	7	-	27869803	HPAFII	viability after 27 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	0.028020355496731986	[144]	[74,79,NaN]	0	hSpCas9	negative selection	9600557
95311539	95311562	7	+	27869803	HPAFII	viability after 27 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	1.0828586798536144	[103]	[165,73,NaN]	8	hSpCas9	negative selection	9600558
95316748	95316771	7	-	27869803	HPAFII	viability after 27 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.2196007638046925	[108]	[87,48,NaN]	1	hSpCas9	negative selection	9600559
95318368	95318391	7	-	27869803	HPAFII	viability after 27 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-1.6366473542732034	[313]	[63,43,NaN]	-8	hSpCas9	negative selection	9600560
95324455	95324478	7	+	27869803	HPAFII	viability after 27 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-1.6432724469300166	[147]	[31,18,NaN]	-8	hSpCas9	negative selection	9600561
95302255	95302278	7	+	27869803	HPAFII	viability after 15 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-0.8207570490117642	[228]	[163,123,NaN]	-7	hSpCas9	negative selection	9683005
95308053	95308076	7	-	27869803	HPAFII	viability after 15 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	0.3461039045448157	[144]	[231,176,NaN]	4	hSpCas9	negative selection	9683006
95311539	95311562	7	+	27869803	HPAFII	viability after 15 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.03291861503789151	[103]	[130,103,NaN]	0	hSpCas9	negative selection	9683007
95316748	95316771	7	-	27869803	HPAFII	viability after 15 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.36887706328194914	[108]	[244,92,NaN]	4	hSpCas9	negative selection	9683008
95318368	95318391	7	-	27869803	HPAFII	viability after 15 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-1.0473982485905067	[313]	[293,81,NaN]	-8	hSpCas9	negative selection	9683009
95324455	95324478	7	+	27869803	HPAFII	viability after 15 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.5064369063103805	[147]	[164,78,NaN]	-5	hSpCas9	negative selection	9683010
95302255	95302278	7	+	27869803	ASPC1	viability after 36 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.5086366394604186	[408]	[200,272,146]	5	hSpCas9	negative selection	9765454
95308053	95308076	7	-	27869803	ASPC1	viability after 36 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	-0.2259933940048281	[370]	[62,72,172]	-2	hSpCas9	negative selection	9765455
95311539	95311562	7	+	27869803	ASPC1	viability after 36 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.16851755599296925	[241]	[77,129,77]	1	hSpCas9	negative selection	9765456
95316748	95316771	7	-	27869803	ASPC1	viability after 36 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.5639434006150759	[304]	[12,155,45]	-5	hSpCas9	negative selection	9765457
95318368	95318391	7	-	27869803	ASPC1	viability after 36 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-1.3062530746585603	[964]	[146,235,47]	-8	hSpCas9	negative selection	9765458
95324455	95324478	7	+	27869803	ASPC1	viability after 36 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.8364518267060952	[427]	[653,241,11]	7	hSpCas9	negative selection	9765459
95302255	95302278	7	+	27869803	PATU8988S	viability after 35 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.49357934569988987	[402]	[236,219,NaN]	5	hSpCas9	negative selection	9847903
95308053	95308076	7	-	27869803	PATU8988S	viability after 35 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	0.09959666900767783	[305]	[153,109,NaN]	1	hSpCas9	negative selection	9847904
95311539	95311562	7	+	27869803	PATU8988S	viability after 35 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.6248083995877964	[336]	[336,80,NaN]	7	hSpCas9	negative selection	9847905
95316748	95316771	7	-	27869803	PATU8988S	viability after 35 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.14576821305505683	[227]	[83,81,NaN]	-1	hSpCas9	negative selection	9847906
95318368	95318391	7	-	27869803	PATU8988S	viability after 35 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.23054037035838748	[758]	[278,241,NaN]	-2	hSpCas9	negative selection	9847907
95324455	95324478	7	+	27869803	PATU8988S	viability after 35 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.753588731334027	[393]	[283,250,NaN]	7	hSpCas9	negative selection	9847908
95302255	95302278	7	+	27869803	PATU8988S	viability after 31 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.3964919516542165	[402]	[218,201,NaN]	5	hSpCas9	negative selection	9930352
95308053	95308076	7	-	27869803	PATU8988S	viability after 31 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	0.6816846045476371	[305]	[167,230,NaN]	7	hSpCas9	negative selection	9930353
95311539	95311562	7	+	27869803	PATU8988S	viability after 31 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	0.7089749927516698	[336]	[304,110,NaN]	8	hSpCas9	negative selection	9930354
95316748	95316771	7	-	27869803	PATU8988S	viability after 31 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.18001418040344075	[227]	[80,130,NaN]	2	hSpCas9	negative selection	9930355
95318368	95318391	7	-	27869803	PATU8988S	viability after 31 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.1929371391333526	[758]	[273,252,NaN]	-2	hSpCas9	negative selection	9930356
95324455	95324478	7	+	27869803	PATU8988S	viability after 31 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.40340739096913314	[393]	[165,260,NaN]	5	hSpCas9	negative selection	9930357
95302255	95302278	7	+	27869803	HPAFII	viability after 35 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-0.270787192354883	[228]	[41,156,NaN]	-2	hSpCas9	negative selection	10012801
95308053	95308076	7	-	27869803	HPAFII	viability after 35 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	0.02039089558695828	[144]	[33,119,NaN]	0	hSpCas9	negative selection	10012802
95311539	95311562	7	+	27869803	HPAFII	viability after 35 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	1.024554015402084	[103]	[84,131,NaN]	7	hSpCas9	negative selection	10012803
95316748	95316771	7	-	27869803	HPAFII	viability after 35 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.8765127999172917	[108]	[129,68,NaN]	6	hSpCas9	negative selection	10012804
95318368	95318391	7	-	27869803	HPAFII	viability after 35 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.512783453941622	[313]	[109,112,NaN]	-3	hSpCas9	negative selection	10012805
95324455	95324478	7	+	27869803	HPAFII	viability after 35 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-2.2922405362948117	[147]	[19,9,NaN]	-8	hSpCas9	negative selection	10012806
95302255	95302278	7	+	27869803	HPAFII	viability after 31 days	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-0.2838545709372491	[228]	[39,176,NaN]	-2	hSpCas9	negative selection	10095250
95308053	95308076	7	-	27869803	HPAFII	viability after 31 days	GAAGTTCGAGTGGTGGCAGAAGG	PON1	ENSG00000005421	0.43022411144655454	[144]	[45,178,NaN]	3	hSpCas9	negative selection	10095251
95311539	95311562	7	+	27869803	HPAFII	viability after 31 days	CATCTGGATGGTTCACCACCAGG	PON1	ENSG00000005421	1.363946891207245	[103]	[132,168,NaN]	8	hSpCas9	negative selection	10095252
95316748	95316771	7	-	27869803	HPAFII	viability after 31 days	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.04068829890641701	[108]	[69,47,NaN]	0	hSpCas9	negative selection	10095253
95318368	95318391	7	-	27869803	HPAFII	viability after 31 days	ACGACTTAATGCTCTCCGAGAGG	PON1	ENSG00000005421	-0.589036405240596	[313]	[153,76,NaN]	-4	hSpCas9	negative selection	10095254
95324455	95324478	7	+	27869803	HPAFII	viability after 31 days	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-1.061126744820553	[147]	[68,7,NaN]	-6	hSpCas9	negative selection	10095255
95324455	95324478	7	+	28162770	P31FUJ	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.683115178440753	[275]	[201]	-5	hSpCas9	negative selection	10214509
95324397	95324420	7	+	28162770	P31FUJ	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	-0.138619765357671	[251]	[268]	-1	hSpCas9	negative selection	10214510
95311542	95311565	7	+	28162770	P31FUJ	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	-0.08128331806932249	[297]	[330]	-1	hSpCas9	negative selection	10214511
95308014	95308037	7	-	28162770	P31FUJ	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	-0.3796435927436499	[61]	[55]	-3	hSpCas9	negative selection	10214512
95302266	95302289	7	-	28162770	P31FUJ	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-2.826983235164913	[156]	[25]	-9	hSpCas9	negative selection	10214513
95302240	95302263	7	+	28162770	P31FUJ	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	0.4283958821338629	[128]	[203]	5	hSpCas9	negative selection	10214514
95316748	95316771	7	-	28162770	P31FUJ	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.04679021880442992	[217]	[247]	0	hSpCas9	negative selection	10214515
95311554	95311577	7	-	28162770	P31FUJ	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	0.4849383161892298	[694]	[1142]	5	hSpCas9	negative selection	10214516
95302255	95302278	7	+	28162770	P31FUJ	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	1.1571443139016346	[144]	[379]	9	hSpCas9	negative selection	10214517
95324430	95324453	7	+	28162770	P31FUJ	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.7335407972085894	[681]	[481]	-5	hSpCas9	negative selection	10214518
95324455	95324478	7	+	28162770	TF1	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10383875
95324397	95324420	7	+	28162770	TF1	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10383876
95311542	95311565	7	+	28162770	TF1	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	NaN	[NaN]	[179]	1	hSpCas9	negative selection	10383877
95308014	95308037	7	-	28162770	TF1	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10383878
95302266	95302289	7	-	28162770	TF1	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10383879
95302240	95302263	7	+	28162770	TF1	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	NaN	[NaN]	[236]	1	hSpCas9	negative selection	10383880
95316748	95316771	7	-	28162770	TF1	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	NaN	[NaN]	[44]	1	hSpCas9	negative selection	10383881
95311554	95311577	7	-	28162770	TF1	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	NaN	[NaN]	[744]	1	hSpCas9	negative selection	10383882
95302255	95302278	7	+	28162770	TF1	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10383883
95324430	95324453	7	+	28162770	TF1	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	NaN	[NaN]	[581]	1	hSpCas9	negative selection	10383884
95324455	95324478	7	+	28162770	SKM1	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.33000139542304435	[71]	[159]	3	hSpCas9	negative selection	10553241
95324397	95324420	7	+	28162770	SKM1	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	-0.10071772608806906	[36]	[60]	-1	hSpCas9	negative selection	10553242
95311542	95311565	7	+	28162770	SKM1	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.17799830197799454	[68]	[137]	1	hSpCas9	negative selection	10553243
95308014	95308037	7	-	28162770	SKM1	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	-0.4594316186372973	[20]	[26]	-4	hSpCas9	negative selection	10553244
95302266	95302289	7	-	28162770	SKM1	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-1.6658824961047238	[69]	[38]	-8	hSpCas9	negative selection	10553245
95302240	95302263	7	+	28162770	SKM1	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	0.031608814996471335	[56]	[102]	0	hSpCas9	negative selection	10553246
95316748	95316771	7	-	28162770	SKM1	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.17488272123827997	[52]	[82]	-1	hSpCas9	negative selection	10553247
95311554	95311577	7	-	28162770	SKM1	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	0.6676129261116694	[171]	[482]	6	hSpCas9	negative selection	10553248
95302255	95302278	7	+	28162770	SKM1	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.8624964762500651	[27]	[89]	7	hSpCas9	negative selection	10553249
95324430	95324453	7	+	28162770	SKM1	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.027676724413519427	[142]	[247]	0	hSpCas9	negative selection	10553250
95324455	95324478	7	+	28162770	SKM1	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.33000139542304435	[71]	[159]	3	hSpCas9	negative selection	10722607
95324397	95324420	7	+	28162770	SKM1	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	-0.10071772608806906	[36]	[60]	-1	hSpCas9	negative selection	10722608
95311542	95311565	7	+	28162770	SKM1	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.17799830197799454	[68]	[137]	1	hSpCas9	negative selection	10722609
95308014	95308037	7	-	28162770	SKM1	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	-0.4594316186372973	[20]	[26]	-4	hSpCas9	negative selection	10722610
95302266	95302289	7	-	28162770	SKM1	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-1.6658824961047238	[69]	[38]	-8	hSpCas9	negative selection	10722611
95302240	95302263	7	+	28162770	SKM1	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	0.031608814996471335	[56]	[102]	0	hSpCas9	negative selection	10722612
95316748	95316771	7	-	28162770	SKM1	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.17488272123827997	[52]	[82]	-1	hSpCas9	negative selection	10722613
95311554	95311577	7	-	28162770	SKM1	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	0.6676129261116694	[171]	[482]	6	hSpCas9	negative selection	10722614
95302255	95302278	7	+	28162770	SKM1	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.8624964762500651	[27]	[89]	7	hSpCas9	negative selection	10722615
95324430	95324453	7	+	28162770	SKM1	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.027676724413519427	[142]	[247]	0	hSpCas9	negative selection	10722616
95324455	95324478	7	+	28162770	PL21	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.6954649027257999	[331]	[233]	6	hSpCas9	negative selection	10891973
95324397	95324420	7	+	28162770	PL21	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	1.4044981129955065	[137]	[158]	9	hSpCas9	negative selection	10891974
95311542	95311565	7	+	28162770	PL21	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.18005536844598768	[216]	[106]	1	hSpCas9	negative selection	10891975
95308014	95308037	7	-	28162770	PL21	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	0.20013961448932016	[79]	[39]	1	hSpCas9	negative selection	10891976
95302266	95302289	7	-	28162770	PL21	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-0.6174836430221113	[140]	[39]	-4	hSpCas9	negative selection	10891977
95302240	95302263	7	+	28162770	PL21	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	1.3828319120055106	[199]	[226]	9	hSpCas9	negative selection	10891978
95316748	95316771	7	-	28162770	PL21	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.9333530737944188	[153]	[127]	7	hSpCas9	negative selection	10891979
95311554	95311577	7	-	28162770	PL21	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	0.9617920875069961	[590]	[500]	7	hSpCas9	negative selection	10891980
95302255	95302278	7	+	28162770	PL21	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	1.5820102498329647	[98]	[128]	9	hSpCas9	negative selection	10891981
95324430	95324453	7	+	28162770	PL21	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.03197614637145363	[396]	[168]	0	hSpCas9	negative selection	10891982
95324455	95324478	7	+	28162770	P31FUJ	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.683115178440753	[275]	[201]	-5	hSpCas9	negative selection	11061339
95324397	95324420	7	+	28162770	P31FUJ	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	-0.138619765357671	[251]	[268]	-1	hSpCas9	negative selection	11061340
95311542	95311565	7	+	28162770	P31FUJ	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	-0.08128331806932249	[297]	[330]	-1	hSpCas9	negative selection	11061341
95308014	95308037	7	-	28162770	P31FUJ	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	-0.3796435927436499	[61]	[55]	-3	hSpCas9	negative selection	11061342
95302266	95302289	7	-	28162770	P31FUJ	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-2.826983235164913	[156]	[25]	-9	hSpCas9	negative selection	11061343
95302240	95302263	7	+	28162770	P31FUJ	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	0.4283958821338629	[128]	[203]	5	hSpCas9	negative selection	11061344
95316748	95316771	7	-	28162770	P31FUJ	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.04679021880442992	[217]	[247]	0	hSpCas9	negative selection	11061345
95311554	95311577	7	-	28162770	P31FUJ	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	0.4849383161892298	[694]	[1142]	5	hSpCas9	negative selection	11061346
95302255	95302278	7	+	28162770	P31FUJ	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	1.1571443139016346	[144]	[379]	9	hSpCas9	negative selection	11061347
95324430	95324453	7	+	28162770	P31FUJ	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.7335407972085894	[681]	[481]	-5	hSpCas9	negative selection	11061348
95324455	95324478	7	+	28162770	OCIAML5	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.8125382066773595	[179]	[184]	-5	hSpCas9	negative selection	11230705
95324397	95324420	7	+	28162770	OCIAML5	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	0.3204006251407685	[125]	[283]	2	hSpCas9	negative selection	11230706
95311542	95311565	7	+	28162770	OCIAML5	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	1.067656839792088	[96]	[366]	8	hSpCas9	negative selection	11230707
95308014	95308037	7	-	28162770	OCIAML5	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	1.0305764784978442	[47]	[176]	8	hSpCas9	negative selection	11230708
95302266	95302289	7	-	28162770	OCIAML5	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-0.870925598115313	[76]	[75]	-5	hSpCas9	negative selection	11230709
95302240	95302263	7	+	28162770	OCIAML5	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	1.7687411288038812	[52]	[325]	9	hSpCas9	negative selection	11230710
95316748	95316771	7	-	28162770	OCIAML5	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.8206388244988252	[100]	[321]	7	hSpCas9	negative selection	11230711
95311554	95311577	7	-	28162770	OCIAML5	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	0.7672310830303832	[345]	[1062]	6	hSpCas9	negative selection	11230712
95302255	95302278	7	+	28162770	OCIAML5	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.47341934343655456	[80]	[202]	4	hSpCas9	negative selection	11230713
95324430	95324453	7	+	28162770	OCIAML5	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.18397247694693553	[398]	[633]	-1	hSpCas9	negative selection	11230714
95324455	95324478	7	+	28162770	EOL1	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-1.2886962675517282	[523]	[112]	-7	hSpCas9	negative selection	11400071
95324397	95324420	7	+	28162770	EOL1	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	0.01765717596201588	[164]	[87]	0	hSpCas9	negative selection	11400072
95311542	95311565	7	+	28162770	EOL1	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.24355838307560257	[395]	[246]	2	hSpCas9	negative selection	11400073
95308014	95308037	7	-	28162770	EOL1	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	0.8817981241111975	[136]	[132]	7	hSpCas9	negative selection	11400074
95302266	95302289	7	-	28162770	EOL1	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-1.5933005332920847	[314]	[54]	-7	hSpCas9	negative selection	11400075
95302240	95302263	7	+	28162770	EOL1	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	0.2640342378422015	[293]	[185]	2	hSpCas9	negative selection	11400076
95316748	95316771	7	-	28162770	EOL1	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.7520805755657689	[212]	[188]	6	hSpCas9	negative selection	11400077
95311554	95311577	7	-	28162770	EOL1	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	0.4983983171714661	[781]	[581]	4	hSpCas9	negative selection	11400078
95302255	95302278	7	+	28162770	EOL1	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	1.450616583238122	[149]	[215]	9	hSpCas9	negative selection	11400079
95324430	95324453	7	+	28162770	EOL1	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.44304256530584896	[657]	[254]	-3	hSpCas9	negative selection	11400080
95324455	95324478	7	+	28162770	MOLM13	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.7146482476655422	[519]	[616]	5	hSpCas9	negative selection	11569437
95324397	95324420	7	+	28162770	MOLM13	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	-0.12984041525045525	[226]	[149]	-1	hSpCas9	negative selection	11569438
95311542	95311565	7	+	28162770	MOLM13	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.6062175380925523	[317]	[349]	4	hSpCas9	negative selection	11569439
95308014	95308037	7	-	28162770	MOLM13	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	0.09284995019765407	[165]	[127]	0	hSpCas9	negative selection	11569440
95302266	95302289	7	-	28162770	MOLM13	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-1.175966808230146	[224]	[71]	-6	hSpCas9	negative selection	11569441
95302240	95302263	7	+	28162770	MOLM13	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	0.9868778448623309	[260]	[373]	7	hSpCas9	negative selection	11569442
95316748	95316771	7	-	28162770	MOLM13	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	-0.0027404436975821955	[193]	[139]	0	hSpCas9	negative selection	11569443
95311554	95311577	7	-	28162770	MOLM13	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	0.2655598385313771	[725]	[630]	2	hSpCas9	negative selection	11569444
95302255	95302278	7	+	28162770	MOLM13	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.3655276639149012	[145]	[135]	2	hSpCas9	negative selection	11569445
95324430	95324453	7	+	28162770	MOLM13	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.7163624013968353	[758]	[333]	-4	hSpCas9	negative selection	11569446
95324455	95324478	7	+	28162770	HEL	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.6885425216134817	[464]	[479]	6	hSpCas9	negative selection	11738803
95324397	95324420	7	+	28162770	HEL	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	-0.1298506718965705	[204]	[119]	-1	hSpCas9	negative selection	11738804
95311542	95311565	7	+	28162770	HEL	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.4660942327516763	[268]	[237]	4	hSpCas9	negative selection	11738805
95308014	95308037	7	-	28162770	HEL	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	-0.1675999484960684	[120]	[68]	-1	hSpCas9	negative selection	11738806
95302266	95302289	7	-	28162770	HEL	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-1.5302075214171924	[238]	[52]	-7	hSpCas9	negative selection	11738807
95302240	95302263	7	+	28162770	HEL	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	0.8032035041936031	[203]	[227]	7	hSpCas9	negative selection	11738808
95316748	95316771	7	-	28162770	HEL	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	1.2153176082656807	[194]	[289]	9	hSpCas9	negative selection	11738809
95311554	95311577	7	-	28162770	HEL	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	0.8099747459150293	[715]	[803]	7	hSpCas9	negative selection	11738810
95302255	95302278	7	+	28162770	HEL	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.9693893371301224	[121]	[152]	8	hSpCas9	negative selection	11738811
95324430	95324453	7	+	28162770	HEL	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.2334216050319875	[568]	[309]	-2	hSpCas9	negative selection	11738812
95324455	95324478	7	+	28162770	MV411	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.45948802789776416	[239]	[277]	4	hSpCas9	negative selection	11908169
95324397	95324420	7	+	28162770	MV411	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	0.92677000210133	[142]	[228]	8	hSpCas9	negative selection	11908170
95311542	95311565	7	+	28162770	MV411	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	-0.1601054119491443	[255]	[192]	-1	hSpCas9	negative selection	11908171
95308014	95308037	7	-	28162770	MV411	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	-0.4760448140198088	[70]	[42]	-4	hSpCas9	negative selection	11908172
95302266	95302289	7	-	28162770	MV411	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-0.8900659729671595	[142]	[64]	-6	hSpCas9	negative selection	11908173
95302240	95302263	7	+	28162770	MV411	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	0.3330132824888492	[179]	[190]	3	hSpCas9	negative selection	11908174
95316748	95316771	7	-	28162770	MV411	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	1.2967652631463435	[114]	[237]	9	hSpCas9	negative selection	11908175
95311554	95311577	7	-	28162770	MV411	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	0.19963682998107224	[582]	[563]	1	hSpCas9	negative selection	11908176
95302255	95302278	7	+	28162770	MV411	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	-0.34750903851100284	[144]	[95]	-3	hSpCas9	negative selection	11908177
95324430	95324453	7	+	28162770	MV411	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.2462097831924348	[527]	[374]	-2	hSpCas9	negative selection	11908178
95324455	95324478	7	+	28162770	MONOMAC1	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	0.06714757481033562	[208]	[250]	0	hSpCas9	negative selection	12077535
95324397	95324420	7	+	28162770	MONOMAC1	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	0.29828844117692604	[82]	[116]	3	hSpCas9	negative selection	12077536
95311542	95311565	7	+	28162770	MONOMAC1	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	-0.5570803145184655	[162]	[126]	-5	hSpCas9	negative selection	12077537
95308014	95308037	7	-	28162770	MONOMAC1	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	0.3677477717239719	[47]	[70]	3	hSpCas9	negative selection	12077538
95302266	95302289	7	-	28162770	MONOMAC1	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-0.7308604987889087	[96]	[66]	-5	hSpCas9	negative selection	12077539
95302240	95302263	7	+	28162770	MONOMAC1	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	0.21427756617657281	[96]	[128]	2	hSpCas9	negative selection	12077540
95316748	95316771	7	-	28162770	MONOMAC1	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.6774322708565873	[83]	[153]	6	hSpCas9	negative selection	12077541
95311554	95311577	7	-	28162770	MONOMAC1	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	0.6338806011809861	[320]	[570]	6	hSpCas9	negative selection	12077542
95302255	95302278	7	+	28162770	MONOMAC1	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.35935650146483156	[50]	[74]	3	hSpCas9	negative selection	12077543
95324430	95324453	7	+	28162770	MONOMAC1	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.053911904960956436	[325]	[359]	0	hSpCas9	negative selection	12077544
95324455	95324478	7	+	28162770	OCIAML2	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.3045265347522571	[83]	[376]	-2	hSpCas9	negative selection	12246901
95324397	95324420	7	+	28162770	OCIAML2	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	0.4660081137604093	[31]	[244]	4	hSpCas9	negative selection	12246902
95311542	95311565	7	+	28162770	OCIAML2	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.34753185177202583	[56]	[401]	3	hSpCas9	negative selection	12246903
95308014	95308037	7	-	28162770	OCIAML2	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	-0.2689959640725106	[14]	[68]	-2	hSpCas9	negative selection	12246904
95302266	95302289	7	-	28162770	OCIAML2	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	0.08833746694605035	[27]	[164]	0	hSpCas9	negative selection	12246905
95302240	95302263	7	+	28162770	OCIAML2	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	-0.06297185632891494	[48]	[259]	0	hSpCas9	negative selection	12246906
95316748	95316771	7	-	28162770	OCIAML2	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.8297651080955598	[26]	[265]	7	hSpCas9	negative selection	12246907
95311554	95311577	7	-	28162770	OCIAML2	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	0.22451559322941805	[104]	[679]	2	hSpCas9	negative selection	12246908
95302255	95302278	7	+	28162770	OCIAML2	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	1.540597430181093	[15]	[257]	9	hSpCas9	negative selection	12246909
95324430	95324453	7	+	28162770	OCIAML2	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	-0.44729732141153744	[91]	[373]	-4	hSpCas9	negative selection	12246910
95324455	95324478	7	+	28162770	OCIAML3	viability	GAGCGCAATCAGCTTCGCCATGG	PON1	ENSG00000005421	-0.5214951405397954	[96]	[203]	-4	hSpCas9	negative selection	12416267
95324397	95324420	7	+	28162770	OCIAML3	viability	CTTACTGGTAAGAAGACTGGTGG	PON1	ENSG00000005421	2.039317881958392	[21]	[272]	9	hSpCas9	negative selection	12416268
95311542	95311565	7	+	28162770	OCIAML3	viability	CTGGATGGTTCACCACCAGGAGG	PON1	ENSG00000005421	0.02693415750255973	[65]	[202]	0	hSpCas9	negative selection	12416269
95308014	95308037	7	-	28162770	OCIAML3	viability	GGAATCAACATTTCACCCGATGG	PON1	ENSG00000005421	-0.43050890804128383	[24]	[55]	-3	hSpCas9	negative selection	12416270
95302266	95302289	7	-	28162770	OCIAML3	viability	GAGACAGGAGACCTTTGGGTTGG	PON1	ENSG00000005421	-1.0090451396030071	[47]	[71]	-6	hSpCas9	negative selection	12416271
95302240	95302263	7	+	28162770	OCIAML3	viability	AGATTTTCATGCCATTGGGATGG	PON1	ENSG00000005421	0.059996504826644426	[33]	[106]	0	hSpCas9	negative selection	12416272
95316748	95316771	7	-	28162770	OCIAML3	viability	GGAGATACTGCCTAATGGACTGG	PON1	ENSG00000005421	0.09565223906368636	[30]	[99]	0	hSpCas9	negative selection	12416273
95311554	95311577	7	-	28162770	OCIAML3	viability	TAATGCCATGTACCTCCTGGTGG	PON1	ENSG00000005421	-0.05417451509266691	[183]	[534]	0	hSpCas9	negative selection	12416274
95302255	95302278	7	+	28162770	OCIAML3	viability	TGGGATGGCATCCAACCCAAAGG	PON1	ENSG00000005421	0.9982228608610322	[32]	[198]	8	hSpCas9	negative selection	12416275
95324430	95324453	7	+	28162770	OCIAML3	viability	GTGCCAGTCCCATCCCCAAGAGG	PON1	ENSG00000005421	0.027992239721522427	[140]	[433]	0	hSpCas9	negative selection	12416276