Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5532
• Symbol: PPP3CB
• Description: protein phosphatase 3 catalytic subunit beta

DataSource: http://genomecrispr.dkfz.de/#!/results/PPP3CB

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
73444741	73444764	10	-	26472758	Jiyoye	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	-1.6401303332724835	[61]	[14]	-8	hSpCas9	negative selection	126002
73444724	73444747	10	-	26472758	Jiyoye	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.5744701269035138	[121]	[136]	4	hSpCas9	negative selection	126003
73479481	73479504	10	+	26472758	Jiyoye	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.06203989545718591	[46]	[36]	0	hSpCas9	negative selection	126004
73479432	73479455	10	+	26472758	Jiyoye	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	0.3427266737790312	[205]	[196]	2	hSpCas9	negative selection	126005
73479345	73479368	10	+	26472758	Jiyoye	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	0.9147789995207899	[82]	[117]	6	hSpCas9	negative selection	126006
73471508	73471531	10	-	26472758	Jiyoye	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	-0.02122934151079936	[252]	[187]	0	hSpCas9	negative selection	126007
73471169	73471192	10	+	26472758	Jiyoye	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	0.7586477520072511	[86]	[110]	5	hSpCas9	negative selection	126008
73471154	73471177	10	+	26472758	Jiyoye	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	1.246710709312627	[18]	[33]	7	hSpCas9	negative selection	126009
73446514	73446537	10	-	26472758	Jiyoye	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.19451449818719901	[196]	[169]	1	hSpCas9	negative selection	126010
73444741	73444764	10	-	26472758	KBM7	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	-0.07232934249410516	[215,100]	[113,27]	0	hSpCas9	negative selection	317120
73444724	73444747	10	-	26472758	KBM7	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.4865041642197629	[488,430]	[179,130]	-4	hSpCas9	negative selection	317121
73479481	73479504	10	+	26472758	KBM7	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.29166816995078015	[291,272]	[180,43]	-3	hSpCas9	negative selection	317122
73479432	73479455	10	+	26472758	KBM7	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	0.2753441805230403	[907,845]	[599,409]	3	hSpCas9	negative selection	317123
73479345	73479368	10	+	26472758	KBM7	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.10757107986976355	[411,234]	[148,127]	-1	hSpCas9	negative selection	317124
73471508	73471531	10	-	26472758	KBM7	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	0.7237025556416741	[1094,914]	[691,852]	7	hSpCas9	negative selection	317125
73471169	73471192	10	+	26472758	KBM7	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	0.5483368263933783	[552,517]	[391,347]	6	hSpCas9	negative selection	317126
73471154	73471177	10	+	26472758	KBM7	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	0.14311378719536066	[283,330]	[110,206]	1	hSpCas9	negative selection	317127
73446514	73446537	10	-	26472758	KBM7	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.491105712856786	[652,435]	[424,290]	5	hSpCas9	negative selection	317128
73444741	73444764	10	-	26472758	Raji	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	-1.3188812193284982	[42]	[3]	-7	hSpCas9	negative selection	508238
73444724	73444747	10	-	26472758	Raji	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.32150834072644674	[199]	[57]	3	hSpCas9	negative selection	508239
73479481	73479504	10	+	26472758	Raji	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-1.1921767464853081	[127]	[12]	-7	hSpCas9	negative selection	508240
73479432	73479455	10	+	26472758	Raji	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	0.7942256501139691	[327]	[131]	7	hSpCas9	negative selection	508241
73479345	73479368	10	+	26472758	Raji	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	0.1488034627535802	[205]	[52]	1	hSpCas9	negative selection	508242
73471508	73471531	10	-	26472758	Raji	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	0.6550374727895818	[456]	[166]	6	hSpCas9	negative selection	508243
73471169	73471192	10	+	26472758	Raji	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	0.316330425645096	[307]	[88]	3	hSpCas9	negative selection	508244
73471154	73471177	10	+	26472758	Raji	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	0.6548713306760927	[103]	[37]	6	hSpCas9	negative selection	508245
73446514	73446537	10	-	26472758	Raji	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.8873350545054508	[204]	[87]	7	hSpCas9	negative selection	508246
73444741	73444764	10	-	26472758	K562	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	0.2657923784590137	[66]	[67]	2	hSpCas9	negative selection	699356
73444724	73444747	10	-	26472758	K562	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.10768751588594028	[470]	[368]	0	hSpCas9	negative selection	699357
73479481	73479504	10	+	26472758	K562	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.6199261729759871	[141]	[77]	-4	hSpCas9	negative selection	699358
73479432	73479455	10	+	26472758	K562	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	-1.3405437730547094	[656]	[218]	-6	hSpCas9	negative selection	699359
73479345	73479368	10	+	26472758	K562	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	0.4228940324726879	[242]	[274]	3	hSpCas9	negative selection	699360
73471508	73471531	10	-	26472758	K562	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	0.50255017197284	[785]	[939]	4	hSpCas9	negative selection	699361
73471169	73471192	10	+	26472758	K562	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	0.1669093604455315	[324]	[307]	1	hSpCas9	negative selection	699362
73471154	73471177	10	+	26472758	K562	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	-0.09768724915854587	[269]	[212]	0	hSpCas9	negative selection	699363
73446514	73446537	10	-	26472758	K562	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.7086490512679128	[381]	[526]	6	hSpCas9	negative selection	699364
73438250	73438273	10	+	26627737	DLD1	viability	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	0.08987042158314162	[1599]	[510,723,391]	0	hSpCas9	negative selection	775635
73444724	73444747	10	-	26627737	DLD1	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.35159124283178145	[916]	[423,417,271]	3	hSpCas9	negative selection	775636
73479449	73479472	10	-	26627737	DLD1	viability	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-0.9441628898700052	[306]	[57,68,26]	-7	hSpCas9	negative selection	775637
73479450	73479473	10	-	26627737	DLD1	viability	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-0.24169626145684997	[312]	[107,84,58]	-3	hSpCas9	negative selection	775638
73438250	73438273	10	+	26627737	GBM cells	viability after 5 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.3133897288271785	[569]	[262,228]	-5	hSpCas9	negative selection	857950
73444724	73444747	10	-	26627737	GBM cells	viability after 5 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.3346969557281405	[396]	[250,285]	5	hSpCas9	negative selection	857951
73479449	73479472	10	-	26627737	GBM cells	viability after 5 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-0.17297904359610017	[143]	[47,88]	-3	hSpCas9	negative selection	857952
73479450	73479473	10	-	26627737	GBM cells	viability after 5 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-0.618144561333667	[165]	[61,53]	-7	hSpCas9	negative selection	857953
73438250	73438273	10	+	26627737	GBM cells	viability after 13 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.4875510370896018	[569]	[283,168]	-5	hSpCas9	negative selection	940265
73444724	73444747	10	-	26627737	GBM cells	viability after 13 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.238084931474412	[396]	[290,223]	3	hSpCas9	negative selection	940266
73479449	73479472	10	-	26627737	GBM cells	viability after 13 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.04401714476338048	[143]	[79,80]	0	hSpCas9	negative selection	940267
73479450	73479473	10	-	26627737	GBM cells	viability after 13 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-0.6863393027447947	[165]	[66,46]	-7	hSpCas9	negative selection	940268
73438250	73438273	10	+	26627737	GBM cells	viability after 21 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.6743414907753291	[569]	[192,194]	-5	hSpCas9	negative selection	1022580
73444724	73444747	10	-	26627737	GBM cells	viability after 21 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.25815072652284826	[396]	[183,176]	-2	hSpCas9	negative selection	1022581
73479449	73479472	10	-	26627737	GBM cells	viability after 21 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-0.04092075366691539	[143]	[74,76]	0	hSpCas9	negative selection	1022582
73479450	73479473	10	-	26627737	GBM cells	viability after 21 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-0.8139192110115746	[165]	[55,46]	-6	hSpCas9	negative selection	1022583
73438250	73438273	10	+	26627737	RPE1	viability after 9 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-1.1460568141753864	[1982]	[135,466]	-7	hSpCas9	negative selection	1104895
73444724	73444747	10	-	26627737	RPE1	viability after 9 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.15264789171922133	[1822]	[812,403]	1	hSpCas9	negative selection	1104896
73479449	73479472	10	-	26627737	RPE1	viability after 9 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.3314921290974584	[230]	[28,170]	2	hSpCas9	negative selection	1104897
73479450	73479473	10	-	26627737	RPE1	viability after 9 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-2.8701475626861157	[696]	[45,8]	-9	hSpCas9	negative selection	1104898
73438250	73438273	10	+	26627737	RPE1	viability after 12 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.5456048967883306	[1982]	[313,418]	-4	hSpCas9	negative selection	1187210
73444724	73444747	10	-	26627737	RPE1	viability after 12 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.10285318804826815	[1822]	[473,580]	0	hSpCas9	negative selection	1187211
73479449	73479472	10	-	26627737	RPE1	viability after 12 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-0.19010288337994274	[230]	[33,75]	-1	hSpCas9	negative selection	1187212
73479450	73479473	10	-	26627737	RPE1	viability after 12 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-2.1913514295772014	[696]	[23,58]	-8	hSpCas9	negative selection	1187213
73438250	73438273	10	+	26627737	RPE1	viability after 15 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	0.07319954431403364	[1982]	[328,841]	0	hSpCas9	negative selection	1269525
73444724	73444747	10	-	26627737	RPE1	viability after 15 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.46337873096809834	[1822]	[850,575]	3	hSpCas9	negative selection	1269526
73479449	73479472	10	-	26627737	RPE1	viability after 15 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-1.0097429540672203	[230]	[6,56]	-6	hSpCas9	negative selection	1269527
73479450	73479473	10	-	26627737	RPE1	viability after 15 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-2.4102882488291413	[696]	[31,41]	-8	hSpCas9	negative selection	1269528
73438250	73438273	10	+	26627737	RPE1	viability after 18 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.4715030953147836	[1982]	[136,651]	-3	hSpCas9	negative selection	1351840
73444724	73444747	10	-	26627737	RPE1	viability after 18 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.23555567324480164	[1822]	[614,540]	1	hSpCas9	negative selection	1351841
73479449	73479472	10	-	26627737	RPE1	viability after 18 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-0.5367704004347169	[230]	[12,74]	-3	hSpCas9	negative selection	1351842
73479450	73479473	10	-	26627737	RPE1	viability after 18 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-2.0829204139736506	[696]	[55,31]	-8	hSpCas9	negative selection	1351843
73438250	73438273	10	+	26627737	HeLa	viability after 8 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.8267136310943374	[1308]	[289,336,328]	-7	hSpCas9	negative selection	1434155
73444724	73444747	10	-	26627737	HeLa	viability after 8 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.6754913449527014	[1269]	[523,233,320]	-6	hSpCas9	negative selection	1434156
73479449	73479472	10	-	26627737	HeLa	viability after 8 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.009558965758654558	[155]	[98,62,50]	0	hSpCas9	negative selection	1434157
73479450	73479473	10	-	26627737	HeLa	viability after 8 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	0.08847213602152826	[198]	[110,56,110]	0	hSpCas9	negative selection	1434158
73438250	73438273	10	+	26627737	HeLa	viability after 12 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.571793925045269	[1308]	[389,397,300]	-5	hSpCas9	negative selection	1516470
73444724	73444747	10	-	26627737	HeLa	viability after 12 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.4938300776075104	[1269]	[300,410,399]	-4	hSpCas9	negative selection	1516471
73479449	73479472	10	-	26627737	HeLa	viability after 12 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-0.8634649723294676	[155]	[37,38,28]	-7	hSpCas9	negative selection	1516472
73479450	73479473	10	-	26627737	HeLa	viability after 12 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-0.8201062640645499	[198]	[102,2,39]	-6	hSpCas9	negative selection	1516473
73438250	73438273	10	+	26627737	HeLa	viability after 15 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.5860980433008223	[1308]	[509,281,263]	-5	hSpCas9	negative selection	1598785
73444724	73444747	10	-	26627737	HeLa	viability after 15 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.24797928540786351	[1269]	[398,442,466]	-2	hSpCas9	negative selection	1598786
73479449	73479472	10	-	26627737	HeLa	viability after 15 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-0.27156276205717234	[155]	[42,85,26]	-2	hSpCas9	negative selection	1598787
73479450	73479473	10	-	26627737	HeLa	viability after 15 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-0.7687126805683681	[198]	[70,27,42]	-6	hSpCas9	negative selection	1598788
73438250	73438273	10	+	26627737	HeLa	viability after 18 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.5823339851444769	[1308]	[345,230,263]	-5	hSpCas9	negative selection	1681100
73444724	73444747	10	-	26627737	HeLa	viability after 18 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.2384171119582008	[1269]	[273,365,466]	-2	hSpCas9	negative selection	1681101
73479449	73479472	10	-	26627737	HeLa	viability after 18 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-0.35006514353756546	[155]	[21,72,26]	-3	hSpCas9	negative selection	1681102
73479450	73479473	10	-	26627737	HeLa	viability after 18 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-0.7254816639225684	[198]	[48,24,42]	-6	hSpCas9	negative selection	1681103
73438250	73438273	10	+	26627737	HCT116	viability after 6 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	0.1383342149374771	[1813]	[416,256]	0	hSpCas9	negative selection	1763415
73444724	73444747	10	-	26627737	HCT116	viability after 6 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.21976081205716813	[1604]	[492,183]	1	hSpCas9	negative selection	1763416
73479449	73479472	10	-	26627737	HCT116	viability after 6 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	2.4504154352287353	[247]	[448,82]	9	hSpCas9	negative selection	1763417
73479450	73479473	10	-	26627737	HCT116	viability after 6 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-1.4508031771500751	[661]	[10,52]	-7	hSpCas9	negative selection	1763418
73438250	73438273	10	+	26627737	HCT116	viability after 8 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.7846515867651959	[978]	[310,363,264]	-7	hSpCas9	negative selection	1845730
73444724	73444747	10	-	26627737	HCT116	viability after 8 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.06611488364281981	[726]	[353,402,498]	0	hSpCas9	negative selection	1845731
73479449	73479472	10	-	26627737	HCT116	viability after 8 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-0.021142568769090264	[134]	[89,38,90]	0	hSpCas9	negative selection	1845732
73479450	73479473	10	-	26627737	HCT116	viability after 8 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-0.5565032453615584	[261]	[94,147,51]	-6	hSpCas9	negative selection	1845733
73438250	73438273	10	+	26627737	HCT116	viability after 9 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.7339327868273091	[1813]	[288,292]	-5	hSpCas9	negative selection	1928045
73444724	73444747	10	-	26627737	HCT116	viability after 9 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.5987554552430496	[1604]	[325,248]	-4	hSpCas9	negative selection	1928046
73479449	73479472	10	-	26627737	HCT116	viability after 9 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.5960786805884426	[247]	[184,32]	4	hSpCas9	negative selection	1928047
73479450	73479473	10	-	26627737	HCT116	viability after 9 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-2.524980577663909	[661]	[42,20]	-9	hSpCas9	negative selection	1928048
73438250	73438273	10	+	26627737	HCT116	viability after 12 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.4814773396555061	[978]	[296,459,356]	-5	hSpCas9	negative selection	2010360
73444724	73444747	10	-	26627737	HCT116	viability after 12 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.04096772198881893	[726]	[294,544,284]	0	hSpCas9	negative selection	2010361
73479449	73479472	10	-	26627737	HCT116	viability after 12 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.10771669185997967	[134]	[90,73,62]	1	hSpCas9	negative selection	2010362
73479450	73479473	10	-	26627737	HCT116	viability after 12 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-0.5885911352222586	[261]	[126,67,75]	-6	hSpCas9	negative selection	2010363
73438250	73438273	10	+	26627737	HCT116	viability after 15 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.5078944114351491	[978]	[324,572,280]	-5	hSpCas9	negative selection	2092675
73444724	73444747	10	-	26627737	HCT116	viability after 15 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.10095734081068852	[726]	[438,516,386]	1	hSpCas9	negative selection	2092676
73479449	73479472	10	-	26627737	HCT116	viability after 15 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.3529774267474519	[134]	[92,76,125]	3	hSpCas9	negative selection	2092677
73479450	73479473	10	-	26627737	HCT116	viability after 15 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-0.7222445898935562	[261]	[71,84,113]	-6	hSpCas9	negative selection	2092678
73438250	73438273	10	+	26627737	HCT116	viability after 18 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.3798631054435144	[978]	[410,328,352]	-3	hSpCas9	negative selection	2174990
73444724	73444747	10	-	26627737	HCT116	viability after 18 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.15191684596249466	[726]	[279,559,316]	1	hSpCas9	negative selection	2174991
73479449	73479472	10	-	26627737	HCT116	viability after 18 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	1.0066140194051796	[134]	[229,33,135]	7	hSpCas9	negative selection	2174992
73479450	73479473	10	-	26627737	HCT116	viability after 18 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-0.41794291549590856	[261]	[72,55,160]	-4	hSpCas9	negative selection	2174993
73482655	73482678	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCCCAGGCTGGAATGCAGTGG	PPP3CB	ENSG00000107758	-0.2783317302750946	[134,222]	[33,30]	-1	dCas9-VP64	positive selection	2393451
73459433	73459456	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGCGCAGTGGCGCGATCTTGG	PPP3CB	ENSG00000107758	-0.814608194487327	[84,35]	[10,2]	-4	dCas9-VP64	positive selection	2398685
73469308	73469331	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGGCAGGCAGATCACTTGAAG	PPP3CB	ENSG00000107758	3.967069992462526	[18,88]	[302,66]	9	dCas9-VP64	positive selection	2403909
73451859	73451882	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCTAGCTACTTGGGAGGCTGGGG	PPP3CB	ENSG00000107758	2.3677236295083457	[37,27]	[69,1]	7	dCas9-VP64	positive selection	2412104
73451776	73451799	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCCAGCCTGGGCGACAGATGG	PPP3CB	ENSG00000107758	1.2012671036636573	[14,1]	[1,5]	5	dCas9-VP64	positive selection	2455026
73482655	73482678	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCCCAGGCTGGAATGCAGTGG	PPP3CB	ENSG00000107758	4.153514066093628	[144,313]	[24,2552]	9	dCas9-VP64	positive selection	2488706
73459433	73459456	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGCGCAGTGGCGCGATCTTGG	PPP3CB	ENSG00000107758	-1.763356426520778	[237,164]	[17,19]	-9	dCas9-VP64	positive selection	2493940
73469308	73469331	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGGCAGGCAGATCACTTGAAG	PPP3CB	ENSG00000107758	0.25134554703064405	[383,209]	[122,108]	2	dCas9-VP64	positive selection	2499164
73451859	73451882	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCTAGCTACTTGGGAGGCTGGGG	PPP3CB	ENSG00000107758	0.1906181633953845	[24,86]	[25,14]	1	dCas9-VP64	positive selection	2507359
73451776	73451799	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCCAGCCTGGGCGACAGATGG	PPP3CB	ENSG00000107758	0.32779538109836626	[14,14]	[4,6]	2	dCas9-VP64	positive selection	2550281
73479486	73479509	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGTCAAGCGATGTGTTGGGGGG	PPP3CB	ENSG00000107758	0.25132280516489014	[5,6]	[5,6]	5	hSpCas9	positive selection	3013257
73478589	73478612	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGATCAAAAAATTGGCCATGG	PPP3CB	ENSG00000107758	0.16006299082381245	[3,4]	[4,3]	3	hSpCas9	positive selection	3013258
73479425	73479448	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGATGTTCTGAAGAACCACTTGG	PPP3CB	ENSG00000107758	-0.08078134542691823	[4,4]	[4,2]	-1	hSpCas9	positive selection	3013259
73479449	73479472	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.11577893923537523	[3,3]	[3,3]	2	hSpCas9	positive selection	3013260
73479486	73479509	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGTCAAGCGATGTGTTGGGGGG	PPP3CB	ENSG00000107758	0.08614306133268945	[5,5]	[5,3]	1	hSpCas9	positive selection	3081115
73478589	73478612	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGATCAAAAAATTGGCCATGG	PPP3CB	ENSG00000107758	0.6929539502913347	[3,3]	[4,4]	9	hSpCas9	positive selection	3081116
73479425	73479448	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGATGTTCTGAAGAACCACTTGG	PPP3CB	ENSG00000107758	-0.33460557268705093	[4,4]	[4,0]	-5	hSpCas9	positive selection	3081117
73479449	73479472	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-0.4630056244757521	[3,3]	[3,0]	-6	hSpCas9	positive selection	3081118
73479481	73479504		+	24336571	A375	resistance to PLX after 7 days	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.21267545511733532	[30,27]	[24,24]	-6	hSpCas9	positive selection	3137419
73479481	73479504		+	24336571	A375	resistance to PLX after 14 days	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.8830881321771997	[32,29]	[7,6]	-9	hSpCas9	positive selection	3195212
73479481	73479504		+	24336571	A375	viability after 7 days	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.6605099171482773	[19]	[30,27]	8	hSpCas9	negative selection	3253005
73479481	73479504		+	24336571	A375	viability after 14 days	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.7584907776191319	[19]	[32,29]	8	hSpCas9	negative selection	3310798
73474911	73474934	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.018921472120756122	[301,301]	[1,1]	0	hSpCas9	positive selection	3387220
73478522	73478545	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.4371472490306473	[112,112]	[0,0]	2	hSpCas9	positive selection	3387221
73475013	73475036	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	-1.404451886326152	[404,404]	[0,0]	-8	hSpCas9	positive selection	3387222
73479485	73479508	10	+	26780180	HT29	viability (Avana library 4 designs)	ATGTCAAGCGATGTGTTGGGGGG	PPP3CB	ENSG00000107758	0.112952271908727	[]	[]	0	hSpCas9	negative selection	3451413
73478588	73478611	10	+	26780180	HT29	viability (Avana library 4 designs)	TCAGATCAAAAAATTGGCCATGG	PPP3CB	ENSG00000107758	-0.382068249756286	[]	[]	-6	hSpCas9	negative selection	3451414
73479425	73479448	10	-	26780180	HT29	viability (Avana library 4 designs)	TGATGTTCTGAAGAACCACTTGG	PPP3CB	ENSG00000107758	-0.422980927614117	[]	[]	-6	hSpCas9	negative selection	3451415
73479449	73479472	10	-	26780180	HT29	viability (Avana library 4 designs)	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	1.74055416916948	[]	[]	6	hSpCas9	negative selection	3451416
73479449	73479472	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.886537517610116	[]	[]	1	hSpCas9	negative selection	3547247
73479425	73479448	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGATGTTCTGAAGAACCACTTGG	PPP3CB	ENSG00000107758	1.00723796197947	[]	[]	1	hSpCas9	negative selection	3547248
73479485	73479508	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGTCAAGCGATGTGTTGGGGGG	PPP3CB	ENSG00000107758	5.67021888340593	[]	[]	8	hSpCas9	negative selection	3547249
73478588	73478611	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGATCAAAAAATTGGCCATGG	PPP3CB	ENSG00000107758	-2.64981299787858	[]	[]	-3	hSpCas9	negative selection	3547250
73474969	73474992	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	-6.59660706636996	[]	[]	-6	hSpCas9	negative selection	3547251
73479373	73479396	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	-7.65642516998799	[]	[]	-7	hSpCas9	negative selection	3547252
73479449	73479472	10	-	26780180	A375	viability (Avana lentiGuide)	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.542990043231994	[]	[]	0	hSpCas9	negative selection	3655906
73479425	73479448	10	-	26780180	A375	viability (Avana lentiGuide)	TGATGTTCTGAAGAACCACTTGG	PPP3CB	ENSG00000107758	-3.28059746762848	[]	[]	-6	hSpCas9	negative selection	3655907
73479485	73479508	10	+	26780180	A375	viability (Avana lentiGuide)	ATGTCAAGCGATGTGTTGGGGGG	PPP3CB	ENSG00000107758	-0.947159790170984	[]	[]	-1	hSpCas9	negative selection	3655908
73478588	73478611	10	+	26780180	A375	viability (Avana lentiGuide)	TCAGATCAAAAAATTGGCCATGG	PPP3CB	ENSG00000107758	-1.82519621788603	[]	[]	-3	hSpCas9	negative selection	3655909
73474969	73474992	10	-	26780180	A375	viability (Avana lentiGuide)	AGCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	-1.1498383549242	[]	[]	-2	hSpCas9	negative selection	3655910
73479373	73479396	10	-	26780180	A375	viability (Avana lentiGuide)	GCGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	0.234791602039924	[]	[]	0	hSpCas9	negative selection	3655911
73479449	73479472	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-0.3120469079420677	[5]	[5,2]	-5	hSpCas9	positive selection	3764513
73479425	73479448	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATGTTCTGAAGAACCACTTGG	PPP3CB	ENSG00000107758	-0.004062072002597797	[5]	[5,5]	0	hSpCas9	positive selection	3764514
73479485	73479508	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGTCAAGCGATGTGTTGGGGGG	PPP3CB	ENSG00000107758	0.19995114316684287	[7]	[8,7]	5	hSpCas9	positive selection	3764515
73478588	73478611	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGATCAAAAAATTGGCCATGG	PPP3CB	ENSG00000107758	-0.15757891329577084	[6]	[5,5]	-3	hSpCas9	positive selection	3764516
73474969	73474992	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	-0.28838333350966916	[6]	[5,4]	-4	hSpCas9	positive selection	3764517
73479373	73479396	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	-0.44770670452806893	[5]	[4,3]	-6	hSpCas9	positive selection	3764518
73479449	73479472	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.17281476020758818	[5]	[5,5]	4	hSpCas9	positive selection	3873120
73479425	73479448	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATGTTCTGAAGAACCACTTGG	PPP3CB	ENSG00000107758	0.05650494760505201	[5]	[6,3]	1	hSpCas9	positive selection	3873121
73479485	73479508	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGTCAAGCGATGTGTTGGGGGG	PPP3CB	ENSG00000107758	0.19084111306823998	[7]	[8,7]	5	hSpCas9	positive selection	3873122
73478588	73478611	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGATCAAAAAATTGGCCATGG	PPP3CB	ENSG00000107758	0.350624664314931	[5]	[6,6]	9	hSpCas9	positive selection	3873123
73474969	73474992	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	0.20066753035699827	[5]	[5,5]	5	hSpCas9	positive selection	3873124
73479373	73479396	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	0.13794760676887133	[6]	[6,5]	3	hSpCas9	positive selection	3873125
73478522	73478545	10	+	26780180	A375	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.303158203282795	[]	[]	0	hSpCas9	negative selection	3983712
73474911	73474934	10	+	26780180	A375	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.110531025367611	[]	[]	0	hSpCas9	negative selection	3983713
73479481	73479504	10	+	26780180	A375	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.976087091076463	[]	[]	4	hSpCas9	negative selection	3983714
73475013	73475036	10	-	26780180	A375	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.644533947591612	[]	[]	2	hSpCas9	negative selection	3983715
73479374	73479397	10	-	26780180	A375	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.658085094859445	[]	[]	2	hSpCas9	negative selection	3983716
73478522	73478545	10	+	26780180	HT29	viability (GeCKOv2 library)	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.935834931358379	[]	[]	4	hSpCas9	negative selection	4091678
73474911	73474934	10	+	26780180	HT29	viability (GeCKOv2 library)	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.479857245846703	[]	[]	1	hSpCas9	negative selection	4091679
73479481	73479504	10	+	26780180	HT29	viability (GeCKOv2 library)	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.874112356308878	[]	[]	3	hSpCas9	negative selection	4091680
73475013	73475036	10	-	26780180	HT29	viability (GeCKOv2 library)	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.646312655057291	[]	[]	2	hSpCas9	negative selection	4091681
73479374	73479397	10	-	26780180	HT29	viability (GeCKOv2 library)	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.0893979067931402	[]	[]	0	hSpCas9	negative selection	4091682
73479481	73479504	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.049196659877762616	[4]	[3,2]	1	hSpCas9	positive selection	4162519
73479481	73479504	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.04216501523219929	[5]	[4,2,3,0]	0	hSpCas9	positive selection	4226541
73479481	73479504	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.11850159776019913	[3]	[2,2]	2	hSpCas9	positive selection	4291837
73479374	73479397	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.3837720585099993	[3]	[3,3]	7	hSpCas9	positive selection	4291838
73474911	73474934	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.036649040178827336	[3]	[4,1]	0	hSpCas9	positive selection	4356086
73478522	73478545	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.006113419302123668	[2]	[2,1]	0	hSpCas9	positive selection	4356087
73475013	73475036	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.031025153358565094	[3]	[4,1]	0	hSpCas9	positive selection	4356088
73478583	73478605	10	+	27760321	OCIAML3	viability	TTTCATCAGATCAAAAAATTGG	PPP3CB	ENSG00000107758	1.750306767385195	[16,10]	[11,67]	9	hSpCas9	negative selection	4430173
73479346	73479368	10	+	27760321	OCIAML3	viability	GTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.9449039873034257	[206,183]	[77,80]	-7	hSpCas9	negative selection	4430174
73479373	73479395	10	-	27760321	OCIAML3	viability	CGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	-3.521427934437152	[43,51]	[1,4]	-9	hSpCas9	negative selection	4430175
73474929	73474951	10	+	27760321	OCIAML3	viability	AAAGGTAAAATATTCAGTAAGG	PPP3CB	ENSG00000107758	0.349869932207314	[0,0]	[0,0]	4	hSpCas9	negative selection	4430176
73474969	73474991	10	-	27760321	OCIAML3	viability	GCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	-0.1679013370901028	[231,198]	[126,178]	-2	hSpCas9	negative selection	4430177
73478583	73478605	10	+	27760321	OCIAML2	viability	TTTCATCAGATCAAAAAATTGG	PPP3CB	ENSG00000107758	1.8734779376914572	[16,10]	[33,49]	9	hSpCas9	negative selection	4513636
73479346	73479368	10	+	27760321	OCIAML2	viability	GTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.1893923629948704	[206,183]	[109,175]	-2	hSpCas9	negative selection	4513637
73479373	73479395	10	-	27760321	OCIAML2	viability	CGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	-1.1154256866627112	[43,51]	[2,37]	-8	hSpCas9	negative selection	4513638
73474929	73474951	10	+	27760321	OCIAML2	viability	AAAGGTAAAATATTCAGTAAGG	PPP3CB	ENSG00000107758	0.3011245669422653	[0,0]	[0,0]	4	hSpCas9	negative selection	4513639
73474969	73474991	10	-	27760321	OCIAML2	viability	GCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	0.46862689959257986	[231,198]	[227,256]	6	hSpCas9	negative selection	4513640
73478583	73478605	10	+	27760321	MV411	viability	TTTCATCAGATCAAAAAATTGG	PPP3CB	ENSG00000107758	-0.9846301933453345	[16,10]	[6,0]	-6	hSpCas9	negative selection	4597099
73479346	73479368	10	+	27760321	MV411	viability	GTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	0.05293229434942348	[206,183]	[163,87]	0	hSpCas9	negative selection	4597100
73479373	73479395	10	-	27760321	MV411	viability	CGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	0.4252786622140583	[43,51]	[0,105]	3	hSpCas9	negative selection	4597101
73474929	73474951	10	+	27760321	MV411	viability	AAAGGTAAAATATTCAGTAAGG	PPP3CB	ENSG00000107758	0.5949485011219959	[0,0]	[0,0]	4	hSpCas9	negative selection	4597102
73474969	73474991	10	-	27760321	MV411	viability	GCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	1.718519284298704	[231,198]	[468,462]	9	hSpCas9	negative selection	4597103
73478583	73478605	10	+	27760321	HL60	viability	TTTCATCAGATCAAAAAATTGG	PPP3CB	ENSG00000107758	0.27414586118055073	[16,10]	[17,8]	3	hSpCas9	negative selection	4680562
73479346	73479368	10	+	27760321	HL60	viability	GTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	0.8203586452776843	[206,183]	[200,366]	8	hSpCas9	negative selection	4680563
73479373	73479395	10	-	27760321	HL60	viability	CGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	-0.4424393868176817	[43,51]	[33,23]	-5	hSpCas9	negative selection	4680564
73474929	73474951	10	+	27760321	HL60	viability	AAAGGTAAAATATTCAGTAAGG	PPP3CB	ENSG00000107758	0.2870783393278593	[0,0]	[0,0]	3	hSpCas9	negative selection	4680565
73474969	73474991	10	-	27760321	HL60	viability	GCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	-0.15479327974945134	[231,198]	[112,204]	-2	hSpCas9	negative selection	4680566
73478583	73478605	10	+	27760321	HT1080	viability	TTTCATCAGATCAAAAAATTGG	PPP3CB	ENSG00000107758	-0.4576053764116903	[10,8]	[0,4]	-2	hSpCas9	negative selection	4764025
73479346	73479368	10	+	27760321	HT1080	viability	GTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-6.029980070239602	[183,143]	[0,0]	-9	hSpCas9	negative selection	4764026
73479373	73479395	10	-	27760321	HT1080	viability	CGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	-0.26634986005093486	[51,40]	[2,28]	-1	hSpCas9	negative selection	4764027
73474929	73474951	10	+	27760321	HT1080	viability	AAAGGTAAAATATTCAGTAAGG	PPP3CB	ENSG00000107758	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4764028
73474969	73474991	10	-	27760321	HT1080	viability	GCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	0.6333178254993259	[198,154]	[137,77]	3	hSpCas9	negative selection	4764029
73478583	73478605	10	+	27760321	HT29	viability after 7 days	TTTCATCAGATCAAAAAATTGG	PPP3CB	ENSG00000107758	-2.9101650022833443	[10,8]	[0,0,2]	-9	hSpCas9	negative selection	4847488
73479346	73479368	10	+	27760321	HT29	viability after 7 days	GTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.9450337217236011	[183,143]	[49,192,77]	-8	hSpCas9	negative selection	4847489
73479373	73479395	10	-	27760321	HT29	viability after 7 days	CGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	-0.3785042235097742	[51,40]	[43,88,5]	-5	hSpCas9	negative selection	4847490
73474929	73474951	10	+	27760321	HT29	viability after 7 days	AAAGGTAAAATATTCAGTAAGG	PPP3CB	ENSG00000107758	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4847491
73474969	73474991	10	-	27760321	HT29	viability after 7 days	GCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	0.10732214209501578	[198,154]	[257,270,208]	1	hSpCas9	negative selection	4847492
73478583	73478605	10	+	27760321	HT29	viability after 25 days	TTTCATCAGATCAAAAAATTGG	PPP3CB	ENSG00000107758	1.771177025797145	[10,8]	[15,52,50]	9	hSpCas9	negative selection	4930951
73479346	73479368	10	+	27760321	HT29	viability after 25 days	GTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.5221121650851275	[183,143]	[122,76,198]	-5	hSpCas9	negative selection	4930952
73479373	73479395	10	-	27760321	HT29	viability after 25 days	CGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	-0.7207116176846751	[51,40]	[4,47,46]	-6	hSpCas9	negative selection	4930953
73474929	73474951	10	+	27760321	HT29	viability after 25 days	AAAGGTAAAATATTCAGTAAGG	PPP3CB	ENSG00000107758	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4930954
73474969	73474991	10	-	27760321	HT29	viability after 25 days	GCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	-0.028411572115124573	[198,154]	[154,272,165]	0	hSpCas9	negative selection	4930955
73478583	73478605	10	+	27760321	HT29	viability after 22 days	TTTCATCAGATCAAAAAATTGG	PPP3CB	ENSG00000107758	1.762277712253609	[10,8]	[1,77,38]	9	hSpCas9	negative selection	5014414
73479346	73479368	10	+	27760321	HT29	viability after 22 days	GTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-1.1841783229068314	[183,143]	[21,146,82]	-7	hSpCas9	negative selection	5014415
73479373	73479395	10	-	27760321	HT29	viability after 22 days	CGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	-1.6163355092239926	[51,40]	[1,38,11]	-7	hSpCas9	negative selection	5014416
73474929	73474951	10	+	27760321	HT29	viability after 22 days	AAAGGTAAAATATTCAGTAAGG	PPP3CB	ENSG00000107758	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5014417
73474969	73474991	10	-	27760321	HT29	viability after 22 days	GCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	0.36771877036863676	[198,154]	[541,129,110]	4	hSpCas9	negative selection	5014418
73478583	73478605	10	+	27760321	HT29	viability after 19 days	TTTCATCAGATCAAAAAATTGG	PPP3CB	ENSG00000107758	0.13127950145113765	[10,8]	[17,0,18]	1	hSpCas9	negative selection	5097877
73479346	73479368	10	+	27760321	HT29	viability after 19 days	GTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.8784411981274671	[183,143]	[148,140,23]	-6	hSpCas9	negative selection	5097878
73479373	73479395	10	-	27760321	HT29	viability after 19 days	CGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	-0.3549900450272663	[51,40]	[0,116,3]	-3	hSpCas9	negative selection	5097879
73474929	73474951	10	+	27760321	HT29	viability after 19 days	AAAGGTAAAATATTCAGTAAGG	PPP3CB	ENSG00000107758	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5097880
73474969	73474991	10	-	27760321	HT29	viability after 19 days	GCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	-0.40984644079774424	[198,154]	[275,97,97]	-4	hSpCas9	negative selection	5097881
73478583	73478605	10	+	27760321	HT29	viability after 16 days	TTTCATCAGATCAAAAAATTGG	PPP3CB	ENSG00000107758	0.20757958381609765	[10,8]	[0,2,33]	2	hSpCas9	negative selection	5181340
73479346	73479368	10	+	27760321	HT29	viability after 16 days	GTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.42720040758740185	[183,143]	[110,136,158]	-4	hSpCas9	negative selection	5181341
73479373	73479395	10	-	27760321	HT29	viability after 16 days	CGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	0.3595340773110376	[51,40]	[21,109,62]	4	hSpCas9	negative selection	5181342
73474929	73474951	10	+	27760321	HT29	viability after 16 days	AAAGGTAAAATATTCAGTAAGG	PPP3CB	ENSG00000107758	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5181343
73474969	73474991	10	-	27760321	HT29	viability after 16 days	GCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	0.7490910217827446	[198,154]	[329,334,332]	8	hSpCas9	negative selection	5181344
73478583	73478605	10	+	27760321	HT29	viability after 13 days	TTTCATCAGATCAAAAAATTGG	PPP3CB	ENSG00000107758	0.9483896353081072	[10,8]	[0,2,60]	9	hSpCas9	negative selection	5264803
73479346	73479368	10	+	27760321	HT29	viability after 13 days	GTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.5611880058699892	[183,143]	[50,188,145]	-6	hSpCas9	negative selection	5264804
73479373	73479395	10	-	27760321	HT29	viability after 13 days	CGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	-1.4710381732561184	[51,40]	[20,10,25]	-8	hSpCas9	negative selection	5264805
73474929	73474951	10	+	27760321	HT29	viability after 13 days	AAAGGTAAAATATTCAGTAAGG	PPP3CB	ENSG00000107758	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5264806
73474969	73474991	10	-	27760321	HT29	viability after 13 days	GCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	0.28943860860757165	[198,154]	[401,75,272]	3	hSpCas9	negative selection	5264807
73478583	73478605	10	+	27760321	HT29	viability after 10 days	TTTCATCAGATCAAAAAATTGG	PPP3CB	ENSG00000107758	-0.8956779879054331	[10,8]	[10,0,7]	-7	hSpCas9	negative selection	5348266
73479346	73479368	10	+	27760321	HT29	viability after 10 days	GTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.3502348530196908	[183,143]	[146,167,166]	-4	hSpCas9	negative selection	5348267
73479373	73479395	10	-	27760321	HT29	viability after 10 days	CGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	-1.2897253022371324	[51,40]	[32,33,4]	-8	hSpCas9	negative selection	5348268
73474929	73474951	10	+	27760321	HT29	viability after 10 days	AAAGGTAAAATATTCAGTAAGG	PPP3CB	ENSG00000107758	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5348269
73474969	73474991	10	-	27760321	HT29	viability after 10 days	GCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	0.4264350510056959	[198,154]	[292,221,371]	6	hSpCas9	negative selection	5348270
73478583	73478605	10	+	27760321	MOLM13	viability	TTTCATCAGATCAAAAAATTGG	PPP3CB	ENSG00000107758	1.8172590828099242	[16,10]	[34,20]	9	hSpCas9	negative selection	5431729
73479346	73479368	10	+	27760321	MOLM13	viability	GTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	0.3775209445106509	[206,183]	[242,57]	2	hSpCas9	negative selection	5431730
73479373	73479395	10	-	27760321	MOLM13	viability	CGCTTAGAATTATCAATGAGGG	PPP3CB	ENSG00000107758	-1.970965031371772	[43,51]	[13,0]	-8	hSpCas9	negative selection	5431731
73474929	73474951	10	+	27760321	MOLM13	viability	AAAGGTAAAATATTCAGTAAGG	PPP3CB	ENSG00000107758	0.8210053139495912	[0,0]	[0,0]	6	hSpCas9	negative selection	5431732
73474969	73474991	10	-	27760321	MOLM13	viability	GCACATTATTTCTTCTGAGAGG	PPP3CB	ENSG00000107758	0.46980986355294796	[231,198]	[303,51]	3	hSpCas9	negative selection	5431733
73479481	73479504	10	+	27260156	BXPC3	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.40762699551494946	[468]	[628,613,732,623]	8	hSpCas9	negative selection	5564297
73479374	73479397	10	-	27260156	BXPC3	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.1047328149256389	[804]	[674,749,817,912]	-2	hSpCas9	negative selection	5564298
73474911	73474934	10	+	27260156	BXPC3	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.3233714426285699	[584]	[774,694,775,819]	7	hSpCas9	negative selection	5628546
73478522	73478545	10	+	27260156	BXPC3	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	-0.03649453691100357	[261]	[204,290,289,288]	-1	hSpCas9	negative selection	5628547
73475013	73475036	10	-	27260156	BXPC3	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.03309484404831897	[703]	[700,689,791,845]	0	hSpCas9	negative selection	5628548
73479481	73479504	10	+	27260156	A673	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.028428087851702668	[468]	[707,544,503,554]	0	hSpCas9	negative selection	5685548
73479374	73479397	10	-	27260156	A673	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.12640558211701736	[804]	[1041,776,920,816]	-3	hSpCas9	negative selection	5685549
73474911	73474934	10	+	27260156	A673	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.1987205281242192	[584]	[930,731,736,841]	5	hSpCas9	negative selection	5749797
73478522	73478545	10	+	27260156	A673	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	-0.08448315556115149	[261]	[368,233,269,324]	-2	hSpCas9	negative selection	5749798
73475013	73475036	10	-	27260156	A673	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.0877137141796488	[703]	[968,1000,735,891]	2	hSpCas9	negative selection	5749799
73479481	73479504	10	+	27260156	A375	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.1235108120788905	[468]	[721,483,604,562]	1	hSpCas9	negative selection	5806799
73479374	73479397	10	-	27260156	A375	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.09164090076019393	[804]	[776,867,1184,1136]	1	hSpCas9	negative selection	5806800
73474911	73474934	10	+	27260156	A375	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.7653484293361663	[584]	[934,1618,912,1227]	9	hSpCas9	negative selection	5871048
73478522	73478545	10	+	27260156	A375	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.6242482267458834	[261]	[474,875,347,266]	8	hSpCas9	negative selection	5871049
73475013	73475036	10	-	27260156	A375	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.4744713798396889	[703]	[1179,1125,1323,955]	7	hSpCas9	negative selection	5871050
73479481	73479504	10	+	27260156	COLO741	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.25811329428192714	[468]	[809,586,755]	5	hSpCas9	negative selection	5928050
73479374	73479397	10	-	27260156	COLO741	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.10123546627164126	[804]	[1167,1210,945]	2	hSpCas9	negative selection	5928051
73474911	73474934	10	+	27260156	COLO741	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.19844038395729285	[584]	[855,815,895]	4	hSpCas9	negative selection	5992299
73478522	73478545	10	+	27260156	COLO741	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	-0.20540554334745575	[261]	[330,325,221]	-4	hSpCas9	negative selection	5992300
73475013	73475036	10	-	27260156	COLO741	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.1187143209135777	[703]	[906,1093,924]	2	hSpCas9	negative selection	5992301
73479481	73479504	10	+	27260156	CAL120	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.45704577033520805	[468]	[666,349,296]	-6	hSpCas9	negative selection	6049301
73479374	73479397	10	-	27260156	CAL120	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.11194647462600482	[804]	[1247,1102,923]	1	hSpCas9	negative selection	6049302
73474911	73474934	10	+	27260156	CAL120	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.5496638010697277	[584]	[1431,1068,755]	7	hSpCas9	negative selection	6113550
73478522	73478545	10	+	27260156	CAL120	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.9744693241607851	[261]	[656,622,643]	9	hSpCas9	negative selection	6113551
73475013	73475036	10	-	27260156	CAL120	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.37952398161989165	[703]	[1128,1320,969]	6	hSpCas9	negative selection	6113552
73479481	73479504	10	+	27260156	CADOES1	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.00610025422599858	[468]	[395,255,576,510]	0	hSpCas9	negative selection	6170552
73479374	73479397	10	-	27260156	CADOES1	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.02238004189022924	[804]	[790,905,733,604]	0	hSpCas9	negative selection	6170553
73474911	73474934	10	+	27260156	CADOES1	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.13207920179117338	[584]	[675,654,506,544]	2	hSpCas9	negative selection	6234801
73478522	73478545	10	+	27260156	CADOES1	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.3373169044725304	[261]	[233,465,248,281]	5	hSpCas9	negative selection	6234802
73475013	73475036	10	-	27260156	CADOES1	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.469190334854825	[703]	[1141,739,904,834]	7	hSpCas9	negative selection	6234803
73479481	73479504	10	+	27260156	EWS502	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.25466066567822626	[468]	[309,414,448,509]	-4	hSpCas9	negative selection	6291803
73479374	73479397	10	-	27260156	EWS502	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.04511544157749592	[804]	[789,885,1025,821]	0	hSpCas9	negative selection	6291804
73474911	73474934	10	+	27260156	EWS502	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.4188949543966161	[584]	[806,704,866,947]	7	hSpCas9	negative selection	6356052
73478522	73478545	10	+	27260156	EWS502	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.11613356412417641	[261]	[357,246,178,419]	2	hSpCas9	negative selection	6356053
73475013	73475036	10	-	27260156	EWS502	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.1927259781820082	[703]	[858,893,721,931]	3	hSpCas9	negative selection	6356054
73479481	73479504	10	+	27260156	EW8	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.09639405095525969	[468]	[424,488,222,314]	-2	hSpCas9	negative selection	6413054
73479374	73479397	10	-	27260156	EW8	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.029941382625547464	[804]	[568,746,476,780]	0	hSpCas9	negative selection	6413055
73474911	73474934	10	+	27260156	EW8	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.462010496057415	[584]	[741,611,592,682]	8	hSpCas9	negative selection	6477303
73478522	73478545	10	+	27260156	EW8	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.5402527405318436	[261]	[477,166,195,429]	8	hSpCas9	negative selection	6477304
73475013	73475036	10	-	27260156	EW8	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.29965109100814447	[703]	[947,548,638,707]	5	hSpCas9	negative selection	6477305
73479481	73479504	10	+	27260156	CORL105	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.4616644936005365	[468]	[495,259,432,416]	-7	hSpCas9	negative selection	6534305
73479374	73479397	10	-	27260156	CORL105	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.1127176932803674	[804]	[689,877,1240,728]	-2	hSpCas9	negative selection	6534306
73474911	73474934	10	+	27260156	CORL105	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.2128328458052023	[584]	[726,801,931,732]	4	hSpCas9	negative selection	6598554
73478522	73478545	10	+	27260156	CORL105	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.15742970974048354	[261]	[364,346,441,230]	3	hSpCas9	negative selection	6598555
73475013	73475036	10	-	27260156	CORL105	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.2280644759900451	[703]	[985,1005,1089,798]	4	hSpCas9	negative selection	6598556
73479481	73479504	10	+	27260156	HS294T	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.8049361342716276	[468]	[407,151,445,244]	8	hSpCas9	negative selection	6655556
73479374	73479397	10	-	27260156	HS294T	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.026706388195834263	[804]	[214,229,329,487]	0	hSpCas9	negative selection	6655557
73474911	73474934	10	+	27260156	HS294T	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.34172788776403556	[584]	[223,265,307,367]	4	hSpCas9	negative selection	6719805
73478522	73478545	10	+	27260156	HS294T	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.45834498016733993	[261]	[184,122,116,124]	6	hSpCas9	negative selection	6719806
73475013	73475036	10	-	27260156	HS294T	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.3940068316649824	[703]	[297,267,406,486]	5	hSpCas9	negative selection	6719807
73479481	73479504	10	+	27260156	HCC44	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.1491720332405296	[468]	[652,565,731,435]	2	hSpCas9	negative selection	6776807
73479374	73479397	10	-	27260156	HCC44	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.005139857365297096	[804]	[905,618,1481,783]	0	hSpCas9	negative selection	6776808
73474911	73474934	10	+	27260156	HCC44	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.37125614125416156	[584]	[858,671,1205,768]	6	hSpCas9	negative selection	6841056
73478522	73478545	10	+	27260156	HCC44	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.3352923663989291	[261]	[527,252,419,331]	5	hSpCas9	negative selection	6841057
73475013	73475036	10	-	27260156	HCC44	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.3437310676912123	[703]	[1648,722,838,895]	5	hSpCas9	negative selection	6841058
73479481	73479504	10	+	27260156	G402	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.7499597981959799	[468]	[327,394,165,465]	-7	hSpCas9	negative selection	6898058
73479374	73479397	10	-	27260156	G402	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.346264541750649	[804]	[591,687,1286,502]	-4	hSpCas9	negative selection	6898059
73474911	73474934	10	+	27260156	G402	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.5258532568787826	[584]	[1143,984,788,1194]	6	hSpCas9	negative selection	6962307
73478522	73478545	10	+	27260156	G402	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.4888446813592609	[261]	[398,581,355,455]	6	hSpCas9	negative selection	6962308
73475013	73475036	10	-	27260156	G402	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.6574087101029842	[703]	[1201,1536,952,1693]	7	hSpCas9	negative selection	6962309
73479481	73479504	10	+	27260156	L33	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.17761676556962785	[468]	[452,219,306,643]	4	hSpCas9	negative selection	7019309
73479374	73479397	10	-	27260156	L33	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.03432177612317244	[804]	[860,313,436,818]	-1	hSpCas9	negative selection	7019310
73474911	73474934	10	+	27260156	L33	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.21093248072598453	[584]	[717,306,445,531]	4	hSpCas9	negative selection	7083558
73478522	73478545	10	+	27260156	L33	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.054302879369324764	[261]	[226,95,172,351]	1	hSpCas9	negative selection	7083559
73475013	73475036	10	-	27260156	L33	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	-0.15660676747790403	[703]	[710,211,366,710]	-4	hSpCas9	negative selection	7083560
73479481	73479504	10	+	27260156	K562	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.1012738723683216	[468]	[444,133,464,485]	-1	hSpCas9	negative selection	7140560
73479374	73479397	10	-	27260156	K562	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.8564024377646621	[804]	[446,227,670,243]	-7	hSpCas9	negative selection	7140561
73474911	73474934	10	+	27260156	K562	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.06322326014749813	[584]	[376,786,680,344]	0	hSpCas9	negative selection	7204809
73478522	73478545	10	+	27260156	K562	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.06773367123241147	[261]	[246,107,331,275]	0	hSpCas9	negative selection	7204810
73475013	73475036	10	-	27260156	K562	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.19120198462755889	[703]	[906,604,707,647]	2	hSpCas9	negative selection	7204811
73479481	73479504	10	+	27260156	HT29	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.04507091648462174	[468]	[603,620,578,552]	0	hSpCas9	negative selection	7261811
73479374	73479397	10	-	27260156	HT29	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.06744209177332872	[804]	[988,1155,807,813]	-1	hSpCas9	negative selection	7261812
73474911	73474934	10	+	27260156	HT29	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.08651768948620198	[584]	[749,827,824,632]	1	hSpCas9	negative selection	7326060
73478522	73478545	10	+	27260156	HT29	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.1581473769544357	[261]	[269,418,311,409]	3	hSpCas9	negative selection	7326061
73475013	73475036	10	-	27260156	HT29	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.2703577021871949	[703]	[1096,1062,1108,878]	5	hSpCas9	negative selection	7326062
73479481	73479504	10	+	27260156	MHHES1	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.054429815028503165	[468]	[478,542,645,384]	-1	hSpCas9	negative selection	7383062
73479374	73479397	10	-	27260156	MHHES1	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.2412114905236551	[804]	[762,1042,679,624]	-4	hSpCas9	negative selection	7383063
73474911	73474934	10	+	27260156	MHHES1	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.25781503262919586	[584]	[909,814,604,812]	5	hSpCas9	negative selection	7447311
73478522	73478545	10	+	27260156	MHHES1	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	-0.05369219365221212	[261]	[259,469,219,212]	-1	hSpCas9	negative selection	7447312
73475013	73475036	10	-	27260156	MHHES1	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.48352405445645363	[703]	[1726,1340,994,570]	8	hSpCas9	negative selection	7447313
73479481	73479504	10	+	27260156	MEWO	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.2151955654398301	[468]	[627,499,422]	5	hSpCas9	negative selection	7504313
73479374	73479397	10	-	27260156	MEWO	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.008374123197937289	[804]	[873,743,676]	0	hSpCas9	negative selection	7504314
73474911	73474934	10	+	27260156	MEWO	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.5112366342462078	[584]	[729,840,758]	9	hSpCas9	negative selection	7568562
73478522	73478545	10	+	27260156	MEWO	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.19156666316857152	[261]	[317,297,230]	4	hSpCas9	negative selection	7568563
73475013	73475036	10	-	27260156	MEWO	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	-0.04061127557362387	[703]	[761,534,647]	-1	hSpCas9	negative selection	7568564
73479481	73479504	10	+	27260156	LNCAPCLONEFGC	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.03251467562588707	[468]	[323,482,431,421]	0	hSpCas9	negative selection	7625564
73479374	73479397	10	-	27260156	LNCAPCLONEFGC	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.031047031858965846	[804]	[746,682,900,675]	0	hSpCas9	negative selection	7625565
73474911	73474934	10	+	27260156	LNCAPCLONEFGC	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.5291030797587353	[584]	[731,758,937,655]	8	hSpCas9	negative selection	7689813
73478522	73478545	10	+	27260156	LNCAPCLONEFGC	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	-0.012610893337548501	[261]	[148,306,269,216]	0	hSpCas9	negative selection	7689814
73475013	73475036	10	-	27260156	LNCAPCLONEFGC	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.20433490774832497	[703]	[655,636,1074,628]	3	hSpCas9	negative selection	7689815
73479481	73479504	10	+	27260156	PANC0327	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.46697225427314093	[468]	[509,149,389,1301]	7	hSpCas9	negative selection	7746815
73479374	73479397	10	-	27260156	PANC0327	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.1103535207018248	[804]	[1266,534,855,500]	1	hSpCas9	negative selection	7746816
73474911	73474934	10	+	27260156	PANC0327	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.2780886168433972	[584]	[867,491,747,449]	4	hSpCas9	negative selection	7811064
73478522	73478545	10	+	27260156	PANC0327	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.29165870558848794	[261]	[204,547,255,89]	4	hSpCas9	negative selection	7811065
73475013	73475036	10	-	27260156	PANC0327	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.104884373719491	[703]	[747,653,453,841]	1	hSpCas9	negative selection	7811066
73479481	73479504	10	+	27260156	NCIH2009	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.01702629099214416	[468]	[732,510,716]	0	hSpCas9	negative selection	7868066
73479374	73479397	10	-	27260156	NCIH2009	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.0013847142432173998	[804]	[1284,951,1166]	0	hSpCas9	negative selection	7868067
73474911	73474934	10	+	27260156	NCIH2009	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.6910655341875112	[584]	[1664,919,1446]	8	hSpCas9	negative selection	7932315
73478522	73478545	10	+	27260156	NCIH2009	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.19224704164675288	[261]	[597,446,243]	2	hSpCas9	negative selection	7932316
73475013	73475036	10	-	27260156	NCIH2009	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	-0.11061176950294221	[703]	[890,828,1008]	-1	hSpCas9	negative selection	7932317
73479481	73479504	10	+	27260156	NCIH1373	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-1.3744408632271332	[468]	[324,137,150,58]	-8	hSpCas9	negative selection	7989317
73479374	73479397	10	-	27260156	NCIH1373	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.912293175414651	[804]	[449,392,790,69]	-7	hSpCas9	negative selection	7989318
73474911	73474934	10	+	27260156	NCIH1373	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.6920399401915884	[584]	[1367,911,1288,183]	7	hSpCas9	negative selection	8053566
73478522	73478545	10	+	27260156	NCIH1373	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.20820551004106946	[261]	[437,195,292,122]	2	hSpCas9	negative selection	8053567
73475013	73475036	10	-	27260156	NCIH1373	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.4903326950213922	[703]	[1375,1108,1021,250]	5	hSpCas9	negative selection	8053568
73479481	73479504	10	+	27260156	PATU8902	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.7164737867968949	[468]	[189,376,379,680]	-6	hSpCas9	negative selection	8110568
73479374	73479397	10	-	27260156	PATU8902	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.1550440561365033	[804]	[844,1213,849,1173]	-1	hSpCas9	negative selection	8110569
73474911	73474934	10	+	27260156	PATU8902	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.34091492111115024	[584]	[1053,570,1056,1482]	3	hSpCas9	negative selection	8174817
73478522	73478545	10	+	27260156	PATU8902	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.655013416099308	[261]	[1148,430,333,414]	7	hSpCas9	negative selection	8174818
73475013	73475036	10	-	27260156	PATU8902	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.8160703442676838	[703]	[1614,1877,1641,1786]	8	hSpCas9	negative selection	8174819
73479481	73479504	10	+	27260156	PANC1	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.10018236714524062	[468]	[227,424,388,454]	-2	hSpCas9	negative selection	8231819
73479374	73479397	10	-	27260156	PANC1	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.07040895557783844	[804]	[583,903,813,643]	1	hSpCas9	negative selection	8231820
73474911	73474934	10	+	27260156	PANC1	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.5399503834326773	[584]	[815,775,790,562]	8	hSpCas9	negative selection	8296068
73478522	73478545	10	+	27260156	PANC1	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.6393880223581966	[261]	[558,300,288,248]	9	hSpCas9	negative selection	8296069
73475013	73475036	10	-	27260156	PANC1	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.19805302073196218	[703]	[702,817,742,548]	3	hSpCas9	negative selection	8296070
73479481	73479504	10	+	27260156	PANC0813	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.0016394083067118492	[468]	[527,592,457,614]	0	hSpCas9	negative selection	8353070
73479374	73479397	10	-	27260156	PANC0813	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.12616817263343072	[804]	[1050,782,1291,1004]	2	hSpCas9	negative selection	8353071
73474911	73474934	10	+	27260156	PANC0813	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.5811349487118083	[584]	[979,1329,912,889]	8	hSpCas9	negative selection	8417319
73478522	73478545	10	+	27260156	PANC0813	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.16339635038933864	[261]	[341,369,411,258]	2	hSpCas9	negative selection	8417320
73475013	73475036	10	-	27260156	PANC0813	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.19645891780446323	[703]	[1134,754,1134,790]	3	hSpCas9	negative selection	8417321
73479481	73479504	10	+	27260156	RDES	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.23764377740148707	[468]	[415,449,444,522]	-4	hSpCas9	negative selection	8474321
73479374	73479397	10	-	27260156	RDES	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.025236080297430408	[804]	[730,797,959,1221]	0	hSpCas9	negative selection	8474322
73474911	73474934	10	+	27260156	RDES	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.5508845023014854	[584]	[740,912,1064,1306]	8	hSpCas9	negative selection	8538570
73478522	73478545	10	+	27260156	RDES	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.2829068034767249	[261]	[266,371,297,567]	4	hSpCas9	negative selection	8538571
73475013	73475036	10	-	27260156	RDES	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.4884220920468165	[703]	[903,1193,1010,1493]	7	hSpCas9	negative selection	8538572
73479481	73479504	10	+	27260156	PC3	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.4148108892284129	[468]	[196,331,588,417]	-7	hSpCas9	negative selection	8595572
73479374	73479397	10	-	27260156	PC3	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.30738646483407717	[804]	[501,622,952,621]	-6	hSpCas9	negative selection	8595573
73474911	73474934	10	+	27260156	PC3	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.25843497680140687	[584]	[422,839,1208,555]	5	hSpCas9	negative selection	8659821
73478522	73478545	10	+	27260156	PC3	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.028918642945695683	[261]	[268,225,396,181]	0	hSpCas9	negative selection	8659822
73475013	73475036	10	-	27260156	PC3	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	-0.017381309989552007	[703]	[467,639,917,871]	0	hSpCas9	negative selection	8659823
73479481	73479504	10	+	27260156	PATU8988T	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.1255557794760145	[468]	[559,231,630,530]	2	hSpCas9	negative selection	8716823
73479374	73479397	10	-	27260156	PATU8988T	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.06152370490059422	[804]	[828,711,575,873]	-1	hSpCas9	negative selection	8716824
73474911	73474934	10	+	27260156	PATU8988T	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.21336471369152593	[584]	[592,815,666,551]	3	hSpCas9	negative selection	8781072
73478522	73478545	10	+	27260156	PATU8988T	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	-0.1453332401211922	[261]	[114,289,271,244]	-2	hSpCas9	negative selection	8781073
73475013	73475036	10	-	27260156	PATU8988T	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.018061871571645405	[703]	[779,829,447,715]	0	hSpCas9	negative selection	8781074
73479481	73479504	10	+	27260156	T47D	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.041148315636899725	[468]	[612,572,536,523]	0	hSpCas9	negative selection	8838074
73479374	73479397	10	-	27260156	T47D	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.08298084289439012	[804]	[861,816,932,935]	-2	hSpCas9	negative selection	8838075
73474911	73474934	10	+	27260156	T47D	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.18481067886725128	[584]	[764,675,769,899]	4	hSpCas9	negative selection	8902323
73478522	73478545	10	+	27260156	T47D	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.028979906255948817	[261]	[402,283,256,304]	0	hSpCas9	negative selection	8902324
73475013	73475036	10	-	27260156	T47D	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.1946950887389668	[703]	[835,942,1093,875]	4	hSpCas9	negative selection	8902325
73479481	73479504	10	+	27260156	SU8686	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.057085951354809164	[468]	[399,405,543,447]	-1	hSpCas9	negative selection	8959325
73479374	73479397	10	-	27260156	SU8686	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.13216077265189918	[804]	[602,629,822,910]	-2	hSpCas9	negative selection	8959326
73474911	73474934	10	+	27260156	SU8686	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.5649853160339617	[584]	[835,777,1004,816]	8	hSpCas9	negative selection	9023574
73478522	73478545	10	+	27260156	SU8686	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.2715287315153937	[261]	[256,352,252,402]	4	hSpCas9	negative selection	9023575
73475013	73475036	10	-	27260156	SU8686	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.10070382219164686	[703]	[723,640,764,899]	1	hSpCas9	negative selection	9023576
73479481	73479504	10	+	27260156	SKES1	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.038203551068764545	[468]	[435,596,481,416]	0	hSpCas9	negative selection	9080576
73479374	73479397	10	-	27260156	SKES1	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.058449693259605695	[804]	[1049,756,831,729]	1	hSpCas9	negative selection	9080577
73474911	73474934	10	+	27260156	SKES1	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.4468874032093972	[584]	[703,918,840,719]	8	hSpCas9	negative selection	9144825
73478522	73478545	10	+	27260156	SKES1	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	-0.07731129295948258	[261]	[347,206,278,171]	-2	hSpCas9	negative selection	9144826
73475013	73475036	10	-	27260156	SKES1	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.09044455242661897	[703]	[941,786,651,646]	2	hSpCas9	negative selection	9144827
73479481	73479504	10	+	27260156	TOV112D	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.2447166536890588	[468]	[666,502,623,430]	5	hSpCas9	negative selection	9201827
73479374	73479397	10	-	27260156	TOV112D	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.0724732525723717	[804]	[593,1094,677,764]	-1	hSpCas9	negative selection	9201828
73474911	73474934	10	+	27260156	TOV112D	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.06963319084825803	[584]	[445,830,624,595]	1	hSpCas9	negative selection	9266076
73478522	73478545	10	+	27260156	TOV112D	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	-0.21101269724167393	[261]	[115,289,218,285]	-4	hSpCas9	negative selection	9266077
73475013	73475036	10	-	27260156	TOV112D	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.4591566529265547	[703]	[1172,948,730,1032]	8	hSpCas9	negative selection	9266078
73479481	73479504	10	+	27260156	TC71	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.13124499613829363	[468]	[448,587,590,576]	3	hSpCas9	negative selection	9323078
73479374	73479397	10	-	27260156	TC71	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	0.0084683772868549	[804]	[765,933,824,955]	0	hSpCas9	negative selection	9323079
73474911	73474934	10	+	27260156	TC71	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.24677742972653366	[584]	[800,730,713,728]	6	hSpCas9	negative selection	9387327
73478522	73478545	10	+	27260156	TC71	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	-0.16340176645158566	[261]	[129,264,279,334]	-4	hSpCas9	negative selection	9387328
73475013	73475036	10	-	27260156	TC71	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.16767156954737183	[703]	[750,834,787,1031]	4	hSpCas9	negative selection	9387329
73479481	73479504	10	+	27260156	TC32	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.2296340946201606	[468]	[298,439,761,642]	4	hSpCas9	negative selection	9444329
73479374	73479397	10	-	27260156	TC32	viability	TGCGCTTAGAATTATCAATGAGG	PPP3CB	ENSG00000107758	-0.1292622627056058	[804]	[605,553,863,799]	-2	hSpCas9	negative selection	9444330
73474911	73474934	10	+	27260156	TC32	viability	GTACTCACATTCCTGCTTAAAGG	PPP3CB	ENSG00000107758	0.5431376056245865	[584]	[744,651,987,869]	8	hSpCas9	negative selection	9508578
73478522	73478545	10	+	27260156	TC32	viability	CCACATAATCGCCAAGAAAAAGG	PPP3CB	ENSG00000107758	0.07363338530677455	[261]	[248,155,415,268]	1	hSpCas9	negative selection	9508579
73475013	73475036	10	-	27260156	TC32	viability	TGCAGTGTGTCTTATATTTATGG	PPP3CB	ENSG00000107758	0.39300815812741496	[703]	[900,528,1083,1084]	6	hSpCas9	negative selection	9508580
73438250	73438273	10	+	27869803	HPAFII	viability after 27 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	0.05605501232451271	[407]	[186,252,NaN]	0	hSpCas9	negative selection	9538629
73444724	73444747	10	-	27869803	HPAFII	viability after 27 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.25131969120539965	[600]	[253,274,NaN]	-2	hSpCas9	negative selection	9538630
73479449	73479472	10	-	27869803	HPAFII	viability after 27 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.27197638430068494	[116]	[94,56,NaN]	2	hSpCas9	negative selection	9538631
73479450	73479473	10	-	27869803	HPAFII	viability after 27 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	1.6109036360152482	[133]	[68,336,NaN]	9	hSpCas9	negative selection	9538632
73438250	73438273	10	+	27869803	HPAFII	viability after 15 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	0.480230002282406	[407]	[734,534,NaN]	5	hSpCas9	negative selection	9621078
73444724	73444747	10	-	27869803	HPAFII	viability after 15 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.22566933002797107	[600]	[901,334,NaN]	-3	hSpCas9	negative selection	9621079
73479449	73479472	10	-	27869803	HPAFII	viability after 15 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-0.02184984200249951	[116]	[158,101,NaN]	0	hSpCas9	negative selection	9621080
73479450	73479473	10	-	27869803	HPAFII	viability after 15 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	0.7189486242301397	[133]	[175,274,NaN]	7	hSpCas9	negative selection	9621081
73438250	73438273	10	+	27869803	ASPC1	viability after 36 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.1177323874027838	[1416]	[234,921,235]	-1	hSpCas9	negative selection	9703527
73444724	73444747	10	-	27869803	ASPC1	viability after 36 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.6481473467259959	[1756]	[410,658,160]	-6	hSpCas9	negative selection	9703528
73479449	73479472	10	-	27869803	ASPC1	viability after 36 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	-0.40601762248475237	[313]	[108,115,36]	-4	hSpCas9	negative selection	9703529
73479450	73479473	10	-	27869803	ASPC1	viability after 36 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	0.5810491730076864	[372]	[417,39,158]	6	hSpCas9	negative selection	9703530
73438250	73438273	10	+	27869803	PATU8988S	viability after 35 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	0.15040563630762382	[1164]	[415,625,NaN]	1	hSpCas9	negative selection	9785976
73444724	73444747	10	-	27869803	PATU8988S	viability after 35 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.15620712237920165	[1389]	[772,473,NaN]	1	hSpCas9	negative selection	9785977
73479449	73479472	10	-	27869803	PATU8988S	viability after 35 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.604739187507561	[256]	[114,199,NaN]	6	hSpCas9	negative selection	9785978
73479450	73479473	10	-	27869803	PATU8988S	viability after 35 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-0.4902876886540976	[395]	[129,96,NaN]	-5	hSpCas9	negative selection	9785979
73438250	73438273	10	+	27869803	PATU8988S	viability after 31 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	0.45805781003325485	[1164]	[488,827,NaN]	5	hSpCas9	negative selection	9868425
73444724	73444747	10	-	27869803	PATU8988S	viability after 31 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.1719226552091795	[1389]	[619,629,NaN]	2	hSpCas9	negative selection	9868426
73479449	73479472	10	-	27869803	PATU8988S	viability after 31 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.6839493387349469	[256]	[128,209,NaN]	7	hSpCas9	negative selection	9868427
73479450	73479473	10	-	27869803	PATU8988S	viability after 31 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	-0.32470106416970074	[395]	[122,129,NaN]	-4	hSpCas9	negative selection	9868428
73438250	73438273	10	+	27869803	HPAFII	viability after 35 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.7152761528669868	[407]	[90,164,NaN]	-4	hSpCas9	negative selection	9950874
73444724	73444747	10	-	27869803	HPAFII	viability after 35 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.23600459783139383	[600]	[188,548,NaN]	1	hSpCas9	negative selection	9950875
73479449	73479472	10	-	27869803	HPAFII	viability after 35 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.8196012680112739	[116]	[120,85,NaN]	5	hSpCas9	negative selection	9950876
73479450	73479473	10	-	27869803	HPAFII	viability after 35 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	0.9978748333985431	[133]	[23,260,NaN]	6	hSpCas9	negative selection	9950877
73438250	73438273	10	+	27869803	HPAFII	viability after 31 days	CAGTATGGTTGCCCGTCCCGTGG	PPP3CB	ENSG00000107758	-0.2150681697334223	[407]	[191,202,NaN]	-1	hSpCas9	negative selection	10033323
73444724	73444747	10	-	27869803	HPAFII	viability after 31 days	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.002724542418134801	[600]	[313,363,NaN]	0	hSpCas9	negative selection	10033324
73479449	73479472	10	-	27869803	HPAFII	viability after 31 days	TGATTTGGATGGGATACCCAGGG	PPP3CB	ENSG00000107758	0.8811030287139967	[116]	[152,85,NaN]	6	hSpCas9	negative selection	10033325
73479450	73479473	10	-	27869803	HPAFII	viability after 31 days	TTGATTTGGATGGGATACCCAGG	PPP3CB	ENSG00000107758	1.4238090246613415	[133]	[28,389,NaN]	9	hSpCas9	negative selection	10033326
73444741	73444764	10	-	28162770	P31FUJ	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	-0.1015576711361259	[41]	[45]	-1	hSpCas9	negative selection	10216095
73444724	73444747	10	-	28162770	P31FUJ	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.010409783077930723	[143]	[167]	0	hSpCas9	negative selection	10216096
73479481	73479504	10	+	28162770	P31FUJ	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.4143167723693473	[52]	[82]	4	hSpCas9	negative selection	10216097
73479432	73479455	10	+	28162770	P31FUJ	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	-0.1453393631640394	[351]	[373]	-1	hSpCas9	negative selection	10216098
73479345	73479368	10	+	28162770	P31FUJ	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.09850111270278761	[122]	[134]	-1	hSpCas9	negative selection	10216099
73471508	73471531	10	-	28162770	P31FUJ	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	0.5228594834617324	[551]	[931]	6	hSpCas9	negative selection	10216100
73471169	73471192	10	+	28162770	P31FUJ	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	0.8341288037046084	[357]	[749]	8	hSpCas9	negative selection	10216101
73471154	73471177	10	+	28162770	P31FUJ	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	0.2562358763082422	[113]	[159]	2	hSpCas9	negative selection	10216102
73446514	73446537	10	-	28162770	P31FUJ	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.8087768993370207	[341]	[703]	8	hSpCas9	negative selection	10216103
73444741	73444764	10	-	28162770	TF1	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10385461
73444724	73444747	10	-	28162770	TF1	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10385462
73479481	73479504	10	+	28162770	TF1	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	NaN	[NaN]	[38]	1	hSpCas9	negative selection	10385463
73479432	73479455	10	+	28162770	TF1	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	NaN	[NaN]	[264]	1	hSpCas9	negative selection	10385464
73479345	73479368	10	+	28162770	TF1	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	NaN	[NaN]	[99]	1	hSpCas9	negative selection	10385465
73471508	73471531	10	-	28162770	TF1	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	NaN	[NaN]	[689]	1	hSpCas9	negative selection	10385466
73471169	73471192	10	+	28162770	TF1	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	NaN	[NaN]	[269]	1	hSpCas9	negative selection	10385467
73471154	73471177	10	+	28162770	TF1	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10385468
73446514	73446537	10	-	28162770	TF1	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	NaN	[NaN]	[619]	1	hSpCas9	negative selection	10385469
73444741	73444764	10	-	28162770	SKM1	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	1.3155018257279292	[9]	[43]	9	hSpCas9	negative selection	10554827
73444724	73444747	10	-	28162770	SKM1	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.012939055707498093	[73]	[131]	0	hSpCas9	negative selection	10554828
73479481	73479504	10	+	28162770	SKM1	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.5405683813627027	[20]	[53]	5	hSpCas9	negative selection	10554829
73479432	73479455	10	+	28162770	SKM1	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	0.1605812489005849	[124]	[246]	1	hSpCas9	negative selection	10554830
73479345	73479368	10	+	28162770	SKM1	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.2500953501262956	[36]	[54]	-2	hSpCas9	negative selection	10554831
73471508	73471531	10	-	28162770	SKM1	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	-0.3118069657028216	[131]	[187]	-3	hSpCas9	negative selection	10554832
73471169	73471192	10	+	28162770	SKM1	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	0.3885652879176528	[69]	[161]	4	hSpCas9	negative selection	10554833
73471154	73471177	10	+	28162770	SKM1	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	1.1373563174806485	[26]	[104]	9	hSpCas9	negative selection	10554834
73446514	73446537	10	-	28162770	SKM1	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.6588035714078588	[66]	[186]	6	hSpCas9	negative selection	10554835
73444741	73444764	10	-	28162770	SKM1	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	1.3155018257279292	[9]	[43]	9	hSpCas9	negative selection	10724193
73444724	73444747	10	-	28162770	SKM1	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.012939055707498093	[73]	[131]	0	hSpCas9	negative selection	10724194
73479481	73479504	10	+	28162770	SKM1	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.5405683813627027	[20]	[53]	5	hSpCas9	negative selection	10724195
73479432	73479455	10	+	28162770	SKM1	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	0.1605812489005849	[124]	[246]	1	hSpCas9	negative selection	10724196
73479345	73479368	10	+	28162770	SKM1	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.2500953501262956	[36]	[54]	-2	hSpCas9	negative selection	10724197
73471508	73471531	10	-	28162770	SKM1	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	-0.3118069657028216	[131]	[187]	-3	hSpCas9	negative selection	10724198
73471169	73471192	10	+	28162770	SKM1	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	0.3885652879176528	[69]	[161]	4	hSpCas9	negative selection	10724199
73471154	73471177	10	+	28162770	SKM1	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	1.1373563174806485	[26]	[104]	9	hSpCas9	negative selection	10724200
73446514	73446537	10	-	28162770	SKM1	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.6588035714078588	[66]	[186]	6	hSpCas9	negative selection	10724201
73444741	73444764	10	-	28162770	PL21	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	-2.641162639491622	[42]	[2]	-9	hSpCas9	negative selection	10893559
73444724	73444747	10	-	28162770	PL21	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-1.2058527451865166	[211]	[39]	-7	hSpCas9	negative selection	10893560
73479481	73479504	10	+	28162770	PL21	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	1.2894069525864076	[46]	[49]	9	hSpCas9	negative selection	10893561
73479432	73479455	10	+	28162770	PL21	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	0.4992432750306357	[394]	[242]	4	hSpCas9	negative selection	10893562
73479345	73479368	10	+	28162770	PL21	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.9658703369496091	[183]	[40]	-6	hSpCas9	negative selection	10893563
73471508	73471531	10	-	28162770	PL21	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	0.8322752354350987	[350]	[271]	7	hSpCas9	negative selection	10893564
73471169	73471192	10	+	28162770	PL21	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	-0.6540095190472253	[328]	[90]	-4	hSpCas9	negative selection	10893565
73471154	73471177	10	+	28162770	PL21	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	-2.500300103651772	[129]	[9]	-9	hSpCas9	negative selection	10893566
73446514	73446537	10	-	28162770	PL21	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.7012008576015313	[235]	[166]	6	hSpCas9	negative selection	10893567
73444741	73444764	10	-	28162770	P31FUJ	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	-0.1015576711361259	[41]	[45]	-1	hSpCas9	negative selection	11062925
73444724	73444747	10	-	28162770	P31FUJ	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.010409783077930723	[143]	[167]	0	hSpCas9	negative selection	11062926
73479481	73479504	10	+	28162770	P31FUJ	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.4143167723693473	[52]	[82]	4	hSpCas9	negative selection	11062927
73479432	73479455	10	+	28162770	P31FUJ	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	-0.1453393631640394	[351]	[373]	-1	hSpCas9	negative selection	11062928
73479345	73479368	10	+	28162770	P31FUJ	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.09850111270278761	[122]	[134]	-1	hSpCas9	negative selection	11062929
73471508	73471531	10	-	28162770	P31FUJ	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	0.5228594834617324	[551]	[931]	6	hSpCas9	negative selection	11062930
73471169	73471192	10	+	28162770	P31FUJ	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	0.8341288037046084	[357]	[749]	8	hSpCas9	negative selection	11062931
73471154	73471177	10	+	28162770	P31FUJ	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	0.2562358763082422	[113]	[159]	2	hSpCas9	negative selection	11062932
73446514	73446537	10	-	28162770	P31FUJ	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.8087768993370207	[341]	[703]	8	hSpCas9	negative selection	11062933
73444741	73444764	10	-	28162770	OCIAML5	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	0.2219340105797798	[18]	[39]	1	hSpCas9	negative selection	11232291
73444724	73444747	10	-	28162770	OCIAML5	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-1.3156339640704995	[130]	[94]	-6	hSpCas9	negative selection	11232292
73479481	73479504	10	+	28162770	OCIAML5	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.05482402474452153	[39]	[74]	0	hSpCas9	negative selection	11232293
73479432	73479455	10	+	28162770	OCIAML5	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	1.1142274918490338	[248]	[972]	8	hSpCas9	negative selection	11232294
73479345	73479368	10	+	28162770	OCIAML5	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	1.202974792693965	[44]	[186]	8	hSpCas9	negative selection	11232295
73471508	73471531	10	-	28162770	OCIAML5	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	0.1843276663964024	[273]	[561]	1	hSpCas9	negative selection	11232296
73471169	73471192	10	+	28162770	OCIAML5	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	0.25614264609189974	[198]	[428]	2	hSpCas9	negative selection	11232297
73471154	73471177	10	+	28162770	OCIAML5	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	-0.08653182450101994	[119]	[203]	0	hSpCas9	negative selection	11232298
73446514	73446537	10	-	28162770	OCIAML5	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.4419246475202423	[218]	[536]	4	hSpCas9	negative selection	11232299
73444741	73444764	10	-	28162770	EOL1	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	0.37520918058009967	[59]	[40]	3	hSpCas9	negative selection	11401657
73444724	73444747	10	-	28162770	EOL1	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-1.1069304599026335	[416]	[101]	-6	hSpCas9	negative selection	11401658
73479481	73479504	10	+	28162770	EOL1	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.09651384395729501	[137]	[67]	0	hSpCas9	negative selection	11401659
73479432	73479455	10	+	28162770	EOL1	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	0.2628108084493703	[684]	[432]	2	hSpCas9	negative selection	11401660
73479345	73479368	10	+	28162770	EOL1	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	0.5342327017029219	[269]	[205]	5	hSpCas9	negative selection	11401661
73471508	73471531	10	-	28162770	EOL1	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	0.953743271249268	[586]	[598]	7	hSpCas9	negative selection	11401662
73471169	73471192	10	+	28162770	EOL1	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	0.7665266891228761	[346]	[310]	6	hSpCas9	negative selection	11401663
73471154	73471177	10	+	28162770	EOL1	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	-1.0938307577443203	[157]	[38]	-6	hSpCas9	negative selection	11401664
73446514	73446537	10	-	28162770	EOL1	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.019325996322634445	[323]	[172]	0	hSpCas9	negative selection	11401665
73444741	73444764	10	-	28162770	MOLM13	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	0.7140499688139763	[42]	[50]	5	hSpCas9	negative selection	11571023
73444724	73444747	10	-	28162770	MOLM13	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.04045183757366469	[329]	[231]	0	hSpCas9	negative selection	11571024
73479481	73479504	10	+	28162770	MOLM13	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.8317015574682494	[128]	[165]	6	hSpCas9	negative selection	11571025
73479432	73479455	10	+	28162770	MOLM13	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	1.4501601871122736	[654]	[1293]	9	hSpCas9	negative selection	11571026
73479345	73479368	10	+	28162770	MOLM13	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	0.5427433762287922	[168]	[177]	4	hSpCas9	negative selection	11571027
73471508	73471531	10	-	28162770	MOLM13	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	0.2595504964970379	[646]	[559]	1	hSpCas9	negative selection	11571028
73471169	73471192	10	+	28162770	MOLM13	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	-0.5356423094256744	[408]	[203]	-3	hSpCas9	negative selection	11571029
73471154	73471177	10	+	28162770	MOLM13	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	-1.1689120506961954	[254]	[81]	-6	hSpCas9	negative selection	11571030
73446514	73446537	10	-	28162770	MOLM13	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.7579920305765435	[439]	[537]	6	hSpCas9	negative selection	11571031
73444741	73444764	10	-	28162770	HEL	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	-0.065080416506333	[48]	[29]	0	hSpCas9	negative selection	11740389
73444724	73444747	10	-	28162770	HEL	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	0.03885546938197215	[306]	[201]	0	hSpCas9	negative selection	11740390
73479481	73479504	10	+	28162770	HEL	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	1.4465963098217345	[58]	[102]	9	hSpCas9	negative selection	11740391
73479432	73479455	10	+	28162770	HEL	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	0.8489815133434752	[461]	[532]	7	hSpCas9	negative selection	11740392
73479345	73479368	10	+	28162770	HEL	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	0.8137843733365846	[142]	[160]	7	hSpCas9	negative selection	11740393
73471508	73471531	10	-	28162770	HEL	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	0.7163487391516647	[553]	[582]	6	hSpCas9	negative selection	11740394
73471169	73471192	10	+	28162770	HEL	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	0.5317075196116132	[323]	[299]	4	hSpCas9	negative selection	11740395
73471154	73471177	10	+	28162770	HEL	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	-1.2369669342819314	[183]	[49]	-6	hSpCas9	negative selection	11740396
73446514	73446537	10	-	28162770	HEL	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.45511182882458573	[327]	[287]	4	hSpCas9	negative selection	11740397
73444741	73444764	10	-	28162770	MV411	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	-0.8594776531337365	[27]	[12]	-5	hSpCas9	negative selection	11909755
73444724	73444747	10	-	28162770	MV411	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.3688210804279195	[232]	[151]	-3	hSpCas9	negative selection	11909756
73479481	73479504	10	+	28162770	MV411	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.4895280433834308	[69]	[41]	-4	hSpCas9	negative selection	11909757
73479432	73479455	10	+	28162770	MV411	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	0.28318757573197717	[278]	[285]	2	hSpCas9	negative selection	11909758
73479345	73479368	10	+	28162770	MV411	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.29772394188040596	[142]	[97]	-2	hSpCas9	negative selection	11909759
73471508	73471531	10	-	28162770	MV411	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	0.9575079178859212	[378]	[619]	8	hSpCas9	negative selection	11909760
73471169	73471192	10	+	28162770	MV411	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	1.0207449920127016	[195]	[334]	8	hSpCas9	negative selection	11909761
73471154	73471177	10	+	28162770	MV411	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	0.6083192800147139	[94]	[121]	5	hSpCas9	negative selection	11909762
73446514	73446537	10	-	28162770	MV411	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	1.655315258488753	[201]	[535]	9	hSpCas9	negative selection	11909763
73444741	73444764	10	-	28162770	MONOMAC1	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	-0.8344667676748454	[27]	[17]	-6	hSpCas9	negative selection	12079121
73444724	73444747	10	-	28162770	MONOMAC1	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.5955862235498286	[144]	[109]	-5	hSpCas9	negative selection	12079122
73479481	73479504	10	+	28162770	MONOMAC1	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	-0.4655256829854557	[52]	[43]	-4	hSpCas9	negative selection	12079123
73479432	73479455	10	+	28162770	MONOMAC1	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	-0.8522515438778038	[262]	[166]	-6	hSpCas9	negative selection	12079124
73479345	73479368	10	+	28162770	MONOMAC1	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.9195028715306448	[98]	[59]	-6	hSpCas9	negative selection	12079125
73471508	73471531	10	-	28162770	MONOMAC1	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	0.377278409462094	[271]	[404]	4	hSpCas9	negative selection	12079126
73471169	73471192	10	+	28162770	MONOMAC1	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	-0.12577816388973206	[157]	[165]	-1	hSpCas9	negative selection	12079127
73471154	73471177	10	+	28162770	MONOMAC1	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	-0.2806947761064632	[70]	[66]	-2	hSpCas9	negative selection	12079128
73446514	73446537	10	-	28162770	MONOMAC1	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	-1.471896688290137	[195]	[80]	-8	hSpCas9	negative selection	12079129
73444741	73444764	10	-	28162770	OCIAML2	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	0.3178660695641271	[10]	[75]	3	hSpCas9	negative selection	12248487
73444724	73444747	10	-	28162770	OCIAML2	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.36100533406766294	[37]	[163]	-3	hSpCas9	negative selection	12248488
73479481	73479504	10	+	28162770	OCIAML2	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	2.000675893683428	[10]	[243]	9	hSpCas9	negative selection	12248489
73479432	73479455	10	+	28162770	OCIAML2	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	0.4233794790696249	[59]	[445]	4	hSpCas9	negative selection	12248490
73479345	73479368	10	+	28162770	OCIAML2	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-0.019968416232595987	[29]	[163]	0	hSpCas9	negative selection	12248491
73471508	73471531	10	-	28162770	OCIAML2	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	0.6602176542174605	[78]	[691]	6	hSpCas9	negative selection	12248492
73471169	73471192	10	+	28162770	OCIAML2	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	0.5894911671954097	[46]	[391]	6	hSpCas9	negative selection	12248493
73471154	73471177	10	+	28162770	OCIAML2	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	0.45136766275656576	[18]	[143]	4	hSpCas9	negative selection	12248494
73446514	73446537	10	-	28162770	OCIAML2	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.5033749662248944	[48]	[384]	5	hSpCas9	negative selection	12248495
73444741	73444764	10	-	28162770	OCIAML3	viability	GTGGAGTGTTAGCTGGAGGACGG	PPP3CB	ENSG00000107758	-0.594007640324163	[8]	[17]	-4	hSpCas9	negative selection	12417853
73444724	73444747	10	-	28162770	OCIAML3	viability	GGACGGCAGACCCTGCAAAGTGG	PPP3CB	ENSG00000107758	-0.7329840534729736	[48]	[88]	-5	hSpCas9	negative selection	12417854
73479481	73479504	10	+	28162770	OCIAML3	viability	TCAGATGTCAAGCGATGTGTTGG	PPP3CB	ENSG00000107758	0.657531126671801	[20]	[99]	6	hSpCas9	negative selection	12417855
73479432	73479455	10	+	28162770	OCIAML3	viability	GTTCTTCAGAACATCAACCCTGG	PPP3CB	ENSG00000107758	-0.33986963497876543	[121]	[290]	-3	hSpCas9	negative selection	12417856
73479345	73479368	10	+	28162770	OCIAML3	viability	GGTTTTCTCTCTCCGAAGGATGG	PPP3CB	ENSG00000107758	-1.4095830691867357	[43]	[49]	-7	hSpCas9	negative selection	12417857
73471508	73471531	10	-	28162770	OCIAML3	viability	CAGTTTCTTTGTGTTCATGGTGG	PPP3CB	ENSG00000107758	1.149447290258634	[121]	[816]	8	hSpCas9	negative selection	12417858
73471169	73471192	10	+	28162770	OCIAML3	viability	CACATTGGTCCAAATGCAGGTGG	PPP3CB	ENSG00000107758	-0.2355536694116867	[77]	[199]	-2	hSpCas9	negative selection	12417859
73471154	73471177	10	+	28162770	OCIAML3	viability	GACCATAACAAGTCACACATTGG	PPP3CB	ENSG00000107758	-1.0830457210467839	[39]	[56]	-7	hSpCas9	negative selection	12417860
73446514	73446537	10	-	28162770	OCIAML3	viability	AATTCGAGCAATTGGCAAGATGG	PPP3CB	ENSG00000107758	0.9084927002050203	[77]	[441]	7	hSpCas9	negative selection	12417861