Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 144165
• Symbol: PRICKLE1
• Description: prickle planar cell polarity protein 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PRICKLE1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
42470288	42470311	12	-	26472758	Jiyoye	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	0.802034998847087	[53]	[70]	5	hSpCas9	negative selection	127194
42468735	42468758	12	+	26472758	Jiyoye	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	0.13154093889244622	[22]	[18]	1	hSpCas9	negative selection	127195
42469506	42469529	12	-	26472758	Jiyoye	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	0.9921378822270296	[101]	[152]	6	hSpCas9	negative selection	127196
42468754	42468777	12	+	26472758	Jiyoye	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.266312845666024	[128]	[116]	2	hSpCas9	negative selection	127197
42466347	42466370	12	-	26472758	Jiyoye	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	-0.49219225538763545	[262]	[140]	-4	hSpCas9	negative selection	127198
42466242	42466265	12	+	26472758	Jiyoye	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	0.6239867705790216	[36]	[42]	4	hSpCas9	negative selection	127199
42472457	42472480	12	+	26472758	Jiyoye	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	0.6033988698175191	[150]	[172]	4	hSpCas9	negative selection	127200
42470335	42470358	12	+	26472758	Jiyoye	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.018403536920835344	[126]	[96]	0	hSpCas9	negative selection	127201
42468764	42468787	12	+	26472758	Jiyoye	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	1.1571971284975258	[21]	[36]	7	hSpCas9	negative selection	127202
42470288	42470311	12	-	26472758	KBM7	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	0.07691968824817552	[403,380]	[222,169]	0	hSpCas9	negative selection	318312
42468735	42468758	12	+	26472758	KBM7	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	-0.8966057402960563	[244,168]	[59,43]	-6	hSpCas9	negative selection	318313
42469506	42469529	12	-	26472758	KBM7	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	0.2716920752790738	[986,770]	[700,310]	3	hSpCas9	negative selection	318314
42468754	42468777	12	+	26472758	KBM7	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.9476575640060771	[603,459]	[371,572]	9	hSpCas9	negative selection	318315
42466347	42466370	12	-	26472758	KBM7	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	0.9726769098189985	[650,403]	[534,425]	9	hSpCas9	negative selection	318316
42466242	42466265	12	+	26472758	KBM7	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	0.7139217194637052	[194,101]	[112,109]	7	hSpCas9	negative selection	318317
42472457	42472480	12	+	26472758	KBM7	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	0.07315959731494459	[1299,968]	[469,631]	0	hSpCas9	negative selection	318318
42470335	42470358	12	+	26472758	KBM7	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.017569221020574455	[688,642]	[356,281]	0	hSpCas9	negative selection	318319
42468764	42468787	12	+	26472758	KBM7	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	0.39021900450429503	[96,136]	[31,110]	4	hSpCas9	negative selection	318320
42470288	42470311	12	-	26472758	Raji	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	-0.0019151071172121767	[232]	[53]	0	hSpCas9	negative selection	509430
42468735	42468758	12	+	26472758	Raji	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	0.08429992226055827	[125]	[30]	0	hSpCas9	negative selection	509431
42469506	42469529	12	-	26472758	Raji	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	-0.054887893525277454	[375]	[83]	0	hSpCas9	negative selection	509432
42468754	42468777	12	+	26472758	Raji	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	1.3290475067875327	[282]	[164]	9	hSpCas9	negative selection	509433
42466347	42466370	12	-	26472758	Raji	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	0.37905685948126605	[221]	[66]	3	hSpCas9	negative selection	509434
42466242	42466265	12	+	26472758	Raji	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	0.6143435240934825	[75]	[26]	6	hSpCas9	negative selection	509435
42472457	42472480	12	+	26472758	Raji	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	0.35936275269839757	[654]	[194]	3	hSpCas9	negative selection	509436
42470335	42470358	12	+	26472758	Raji	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.5282266563336488	[247]	[82]	5	hSpCas9	negative selection	509437
42468764	42468787	12	+	26472758	Raji	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	1.6021482271231773	[43]	[30]	9	hSpCas9	negative selection	509438
42470288	42470311	12	-	26472758	K562	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	0.15396377672094336	[361]	[339]	1	hSpCas9	negative selection	700548
42468735	42468758	12	+	26472758	K562	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	-0.13972476366661346	[153]	[117]	-1	hSpCas9	negative selection	700549
42469506	42469529	12	-	26472758	K562	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	0.25686656192924817	[576]	[581]	2	hSpCas9	negative selection	700550
42468754	42468777	12	+	26472758	K562	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.5836608764030865	[380]	[481]	5	hSpCas9	negative selection	700551
42466347	42466370	12	-	26472758	K562	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	0.6490600827448303	[382]	[506]	5	hSpCas9	negative selection	700552
42466242	42466265	12	+	26472758	K562	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	1.3325100572913038	[134]	[286]	9	hSpCas9	negative selection	700553
42472457	42472480	12	+	26472758	K562	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	-0.028290739205128035	[777]	[643]	0	hSpCas9	negative selection	700554
42470335	42470358	12	+	26472758	K562	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.6989845911319281	[377]	[517]	6	hSpCas9	negative selection	700555
42468764	42468787	12	+	26472758	K562	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	-0.5076537588899677	[63]	[37]	-3	hSpCas9	negative selection	700556
42468644	42468667	12	-	26627737	DLD1	viability	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	-0.2983852079554634	[2167]	[532,493,613]	-3	hSpCas9	negative selection	783644
42469557	42469580	12	-	26627737	DLD1	viability	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.11065958604839066	[857]	[285,287,293]	1	hSpCas9	negative selection	783645
42472385	42472408	12	+	26627737	DLD1	viability	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.08964359676678291	[948]	[101,285,425]	-1	hSpCas9	negative selection	783646
42468644	42468667	12	-	26627737	GBM cells	viability after 5 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	-0.1628869815553291	[1096]	[483,566]	-3	hSpCas9	negative selection	865959
42469557	42469580	12	-	26627737	GBM cells	viability after 5 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.011661299550049131	[528]	[296,274]	0	hSpCas9	negative selection	865960
42472385	42472408	12	+	26627737	GBM cells	viability after 5 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.19483262160751114	[301]	[157,124]	-3	hSpCas9	negative selection	865961
42468644	42468667	12	-	26627737	GBM cells	viability after 13 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	-0.04211713510980131	[1096]	[678,495]	0	hSpCas9	negative selection	948274
42469557	42469580	12	-	26627737	GBM cells	viability after 13 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.30387273511519064	[528]	[441,282]	4	hSpCas9	negative selection	948275
42472385	42472408	12	+	26627737	GBM cells	viability after 13 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.3736435125201482	[301]	[174,86]	-4	hSpCas9	negative selection	948276
42468644	42468667	12	-	26627737	GBM cells	viability after 21 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	-0.4345160147693372	[1096]	[452,429]	-4	hSpCas9	negative selection	1030589
42469557	42469580	12	-	26627737	GBM cells	viability after 21 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	-0.1460649642783185	[528]	[277,242]	-1	hSpCas9	negative selection	1030590
42472385	42472408	12	+	26627737	GBM cells	viability after 21 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.8539041730060495	[301]	[95,85]	-6	hSpCas9	negative selection	1030591
42468644	42468667	12	-	26627737	RPE1	viability after 9 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	-0.08667212479469288	[3433]	[897,1159]	0	hSpCas9	negative selection	1112904
42469557	42469580	12	-	26627737	RPE1	viability after 9 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.032285336697777445	[1508]	[507,450]	0	hSpCas9	negative selection	1112905
42472385	42472408	12	+	26627737	RPE1	viability after 9 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.5761483306590435	[551]	[135,89]	-4	hSpCas9	negative selection	1112906
42468644	42468667	12	-	26627737	RPE1	viability after 12 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.06652980403631714	[3433]	[851,1086]	0	hSpCas9	negative selection	1195219
42469557	42469580	12	-	26627737	RPE1	viability after 12 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.5170697604845597	[1508]	[534,627]	3	hSpCas9	negative selection	1195220
42472385	42472408	12	+	26627737	RPE1	viability after 12 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.5550180281593452	[551]	[115,84]	-4	hSpCas9	negative selection	1195221
42468644	42468667	12	-	26627737	RPE1	viability after 15 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.255668459093334	[3433]	[1173,1145]	1	hSpCas9	negative selection	1277534
42469557	42469580	12	-	26627737	RPE1	viability after 15 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.21448050939276786	[1508]	[619,374]	1	hSpCas9	negative selection	1277535
42472385	42472408	12	+	26627737	RPE1	viability after 15 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.6161754038626911	[551]	[80,121]	-4	hSpCas9	negative selection	1277536
42468644	42468667	12	-	26627737	RPE1	viability after 18 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.06156398305028743	[3433]	[1072,853]	0	hSpCas9	negative selection	1359849
42469557	42469580	12	-	26627737	RPE1	viability after 18 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.07590575951556777	[1508]	[435,421]	0	hSpCas9	negative selection	1359850
42472385	42472408	12	+	26627737	RPE1	viability after 18 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-1.5612541174203898	[551]	[78,19]	-7	hSpCas9	negative selection	1359851
42468644	42468667	12	-	26627737	HeLa	viability after 8 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	-0.23862094719473137	[1642]	[703,656,486]	-2	hSpCas9	negative selection	1442164
42469557	42469580	12	-	26627737	HeLa	viability after 8 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.615607134420888	[726]	[628,477,385]	5	hSpCas9	negative selection	1442165
42472385	42472408	12	+	26627737	HeLa	viability after 8 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-1.9143465481843118	[1243]	[193,164,86]	-9	hSpCas9	negative selection	1442166
42468644	42468667	12	-	26627737	HeLa	viability after 12 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	-0.5249114330925289	[1642]	[417,510,480]	-5	hSpCas9	negative selection	1524479
42469557	42469580	12	-	26627737	HeLa	viability after 12 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.38725722794868056	[726]	[590,360,235]	3	hSpCas9	negative selection	1524480
42472385	42472408	12	+	26627737	HeLa	viability after 12 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-1.1084292449617128	[1243]	[323,179,219]	-7	hSpCas9	negative selection	1524481
42468644	42468667	12	-	26627737	HeLa	viability after 15 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	-0.3373675070327218	[1642]	[404,483,714]	-3	hSpCas9	negative selection	1606794
42469557	42469580	12	-	26627737	HeLa	viability after 15 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.2786433911511972	[726]	[240,545,285]	2	hSpCas9	negative selection	1606795
42472385	42472408	12	+	26627737	HeLa	viability after 15 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-1.6132283564332741	[1243]	[128,118,255]	-8	hSpCas9	negative selection	1606796
42468644	42468667	12	-	26627737	HeLa	viability after 18 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	-0.319204115540614	[1642]	[278,407,714]	-3	hSpCas9	negative selection	1689109
42469557	42469580	12	-	26627737	HeLa	viability after 18 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.3125662616895486	[726]	[171,459,285]	2	hSpCas9	negative selection	1689110
42472385	42472408	12	+	26627737	HeLa	viability after 18 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-1.5971121530807901	[1243]	[88,99,255]	-8	hSpCas9	negative selection	1689111
42468644	42468667	12	-	26627737	HCT116	viability after 6 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.6106194997382524	[2229]	[912,326]	3	hSpCas9	negative selection	1771424
42469557	42469580	12	-	26627737	HCT116	viability after 6 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	-0.5095256808098743	[1345]	[176,132]	-3	hSpCas9	negative selection	1771425
42472385	42472408	12	+	26627737	HCT116	viability after 6 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	0.6232004474209158	[2010]	[640,401]	3	hSpCas9	negative selection	1771426
42468644	42468667	12	-	26627737	HCT116	viability after 8 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.15767902253302668	[919]	[575,582,537]	1	hSpCas9	negative selection	1853739
42469557	42469580	12	-	26627737	HCT116	viability after 8 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.1550689476784114	[437]	[340,238,227]	1	hSpCas9	negative selection	1853740
42472385	42472408	12	+	26627737	HCT116	viability after 8 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.12220497535780617	[478]	[156,244,322]	-1	hSpCas9	negative selection	1853741
42468644	42468667	12	-	26627737	HCT116	viability after 9 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.11735096134820067	[2229]	[455,795]	0	hSpCas9	negative selection	1936054
42469557	42469580	12	-	26627737	HCT116	viability after 9 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	-1.134300386090426	[1345]	[89,221]	-7	hSpCas9	negative selection	1936055
42472385	42472408	12	+	26627737	HCT116	viability after 9 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.10432765689877588	[2010]	[589,427]	0	hSpCas9	negative selection	1936056
42468644	42468667	12	-	26627737	HCT116	viability after 12 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.06398894155188262	[919]	[597,459,448]	0	hSpCas9	negative selection	2018369
42469557	42469580	12	-	26627737	HCT116	viability after 12 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.493340107821003	[437]	[290,324,358]	5	hSpCas9	negative selection	2018370
42472385	42472408	12	+	26627737	HCT116	viability after 12 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.4865926718403084	[478]	[246,176,108]	-5	hSpCas9	negative selection	2018371
42468644	42468667	12	-	26627737	HCT116	viability after 15 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.05077491447826299	[919]	[580,439,623]	0	hSpCas9	negative selection	2100684
42469557	42469580	12	-	26627737	HCT116	viability after 15 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	-0.25545637285141737	[437]	[257,175,203]	-3	hSpCas9	negative selection	2100685
42472385	42472408	12	+	26627737	HCT116	viability after 15 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.903321632373948	[478]	[200,116,129]	-7	hSpCas9	negative selection	2100686
42468644	42468667	12	-	26627737	HCT116	viability after 18 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.56415686533169	[919]	[666,600,710]	5	hSpCas9	negative selection	2182999
42469557	42469580	12	-	26627737	HCT116	viability after 18 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.05249493138517869	[437]	[274,177,207]	0	hSpCas9	negative selection	2183000
42472385	42472408	12	+	26627737	HCT116	viability after 18 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	0.09050361047722255	[478]	[276,162,307]	0	hSpCas9	negative selection	2183001
42472384	42472407	12	-	24336569	HL60	viability	CCCGGGCCTGAGACCAGAGCAGG	PRICKLE1	ENSG00000139174	0.04900064610846873	[522]	[1144]	0	hSpCas9	negative selection	2286258
42472411	42472434	12	-	24336569	HL60	viability	TGCATTGGAGGAGTACGCCTGGG	PRICKLE1	ENSG00000139174	-0.13687106590823794	[1764]	[3396]	-1	hSpCas9	negative selection	2286259
42472423	42472446	12	-	24336569	HL60	viability	TGACTCTGGCTGTGCATTGGAGG	PRICKLE1	ENSG00000139174	0.6491225809746048	[407]	[1353]	5	hSpCas9	negative selection	2286260
42472436	42472459	12	+	24336569	HL60	viability	GCCAGAGTCATCATCTGATGTGG	PRICKLE1	ENSG00000139174	1.3073077439561418	[193]	[1015]	8	hSpCas9	negative selection	2286261
42472457	42472480	12	+	24336569	HL60	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	-1.5233635522582172	[776]	[571]	-8	hSpCas9	negative selection	2286262
42472473	42472496	12	-	24336569	HL60	viability	AAGATGAGCAAACTGGCCTTTGG	PRICKLE1	ENSG00000139174	0.9606377322509332	[438]	[1807]	7	hSpCas9	negative selection	2286263
42472480	42472503	12	-	24336569	HL60	viability	GGAGCCCAAGATGAGCAAACTGG	PRICKLE1	ENSG00000139174	0.5328162066100557	[616]	[1888]	5	hSpCas9	negative selection	2286264
42472491	42472514	12	+	24336569	HL60	viability	ATCTTGGGCTCCATCTCCAAAGG	PRICKLE1	ENSG00000139174	0.35494704944251443	[401]	[1087]	3	hSpCas9	negative selection	2286265
42472501	42472524	12	-	24336569	HL60	viability	AAACTTTATGCCTTTGGAGATGG	PRICKLE1	ENSG00000139174	-1.537143584405086	[287]	[209]	-8	hSpCas9	negative selection	2286266
42472507	42472530	12	-	24336569	HL60	viability	GGCTTTAAACTTTATGCCTTTGG	PRICKLE1	ENSG00000139174	-1.131360544875904	[352]	[340]	-8	hSpCas9	negative selection	2286267
42472384	42472407	12	-	24336569	KBM7	viability	CCCGGGCCTGAGACCAGAGCAGG	PRICKLE1	ENSG00000139174	-0.013019139005220032	[366]	[991]	0	hSpCas9	negative selection	2353435
42472411	42472434	12	-	24336569	KBM7	viability	TGCATTGGAGGAGTACGCCTGGG	PRICKLE1	ENSG00000139174	-0.2981924550612951	[1296]	[2876]	-2	hSpCas9	negative selection	2353436
42472423	42472446	12	-	24336569	KBM7	viability	TGACTCTGGCTGTGCATTGGAGG	PRICKLE1	ENSG00000139174	0.05129943008996718	[304]	[861]	0	hSpCas9	negative selection	2353437
42472436	42472459	12	+	24336569	KBM7	viability	GCCAGAGTCATCATCTGATGTGG	PRICKLE1	ENSG00000139174	-0.8297520619220996	[433]	[665]	-6	hSpCas9	negative selection	2353438
42472457	42472480	12	+	24336569	KBM7	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	-0.02534619586583481	[374]	[1004]	0	hSpCas9	negative selection	2353439
42472473	42472496	12	-	24336569	KBM7	viability	AAGATGAGCAAACTGGCCTTTGG	PRICKLE1	ENSG00000139174	-0.8075753322697644	[599]	[934]	-6	hSpCas9	negative selection	2353440
42472480	42472503	12	-	24336569	KBM7	viability	GGAGCCCAAGATGAGCAAACTGG	PRICKLE1	ENSG00000139174	0.5670127113647139	[663]	[2682]	5	hSpCas9	negative selection	2353441
42472491	42472514	12	+	24336569	KBM7	viability	ATCTTGGGCTCCATCTCCAAAGG	PRICKLE1	ENSG00000139174	-0.5282909958081419	[532]	[1007]	-4	hSpCas9	negative selection	2353442
42472501	42472524	12	-	24336569	KBM7	viability	AAACTTTATGCCTTTGGAGATGG	PRICKLE1	ENSG00000139174	0.225919978773931	[157]	[503]	2	hSpCas9	negative selection	2353443
42472507	42472530	12	-	24336569	KBM7	viability	GGCTTTAAACTTTATGCCTTTGG	PRICKLE1	ENSG00000139174	1.0876645645557659	[122]	[712]	8	hSpCas9	negative selection	2353444
42483729	42483752	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATCGCCGCGCTGCGCCGCCAGGG	PRICKLE1	ENSG00000139174	1.7471817229720665	[29,156]	[12,130]	6	dCas9-VP64	positive selection	2402045
42483752	42483775	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGAGGGGCTGCAGCGGGTGAGG	PRICKLE1	ENSG00000139174	-1.7708381322016422	[50,13]	[1,0]	-8	dCas9-VP64	positive selection	2402046
42483777	42483800	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGTGAGGCATCCCACAAAAGG	PRICKLE1	ENSG00000139174	2.4511196172392817	[12,23]	[12,32]	7	dCas9-VP64	positive selection	2402047
42484136	42484159	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAGCGGGCGGCGGCGGGAGCAGG	PRICKLE1	ENSG00000139174	0.025243333435739146	[5,26]	[2,2]	0	dCas9-VP64	positive selection	2402048
42484160	42484183	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGGTCAGCAGTGACAGTTCCTGG	PRICKLE1	ENSG00000139174	0.9904618894607138	[109,777]	[72,328]	4	dCas9-VP64	positive selection	2402049
42484114	42484137	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGGGCAGGCGCCGCCCGCGGG	PRICKLE1	ENSG00000139174	-0.7865873332090363	[121,32]	[14,2]	-4	dCas9-VP64	positive selection	2402050
42589856	42589879	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACGCGTGGGCGCGCGCCCAGCGG	PRICKLE1	ENSG00000139174	0.6117636782497362	[238,41]	[80,8]	2	dCas9-VP64	positive selection	2467976
42589882	42589905	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCGGCTCGGCCCTGAAAGCGAGG	PRICKLE1	ENSG00000139174	-1.6127012368976703	[90,90]	[8,2]	-8	dCas9-VP64	positive selection	2467977
42589926	42589949	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCTCGCAGCCCTGCCCCCGGG	PRICKLE1	ENSG00000139174	-0.5581023005976533	[110,51]	[7,15]	-3	dCas9-VP64	positive selection	2467978
42483729	42483752	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATCGCCGCGCTGCGCCGCCAGGG	PRICKLE1	ENSG00000139174	2.2947853277871553	[245,80]	[73,441]	8	dCas9-VP64	positive selection	2497300
42483752	42483775	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGAGGGGCTGCAGCGGGTGAGG	PRICKLE1	ENSG00000139174	1.8427895286583846	[34,44]	[72,22]	8	dCas9-VP64	positive selection	2497301
42483777	42483800	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGTGAGGCATCCCACAAAAGG	PRICKLE1	ENSG00000139174	0.5368934417957366	[93,74]	[36,42]	4	dCas9-VP64	positive selection	2497302
42484136	42484159	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAGCGGGCGGCGGCGGGAGCAGG	PRICKLE1	ENSG00000139174	-0.5075366931506005	[51,33]	[8,9]	-5	dCas9-VP64	positive selection	2497303
42484160	42484183	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGGTCAGCAGTGACAGTTCCTGG	PRICKLE1	ENSG00000139174	-0.03133024493953229	[96,279]	[43,73]	0	dCas9-VP64	positive selection	2497304
42484114	42484137	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGGGCAGGCGCCGCCCGCGGG	PRICKLE1	ENSG00000139174	0.9370851789877597	[24,27]	[12,19]	6	dCas9-VP64	positive selection	2497305
42589856	42589879	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACGCGTGGGCGCGCGCCCAGCGG	PRICKLE1	ENSG00000139174	-0.6326644549848801	[67,33]	[11,8]	-6	dCas9-VP64	positive selection	2563231
42589882	42589905	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCGGCTCGGCCCTGAAAGCGAGG	PRICKLE1	ENSG00000139174	-0.67464430770805	[83,9]	[10,7]	-6	dCas9-VP64	positive selection	2563232
42589926	42589949	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCTCGCAGCCCTGCCCCCGGG	PRICKLE1	ENSG00000139174	0.15190969353367256	[166,359]	[78,108]	1	dCas9-VP64	positive selection	2563233
42470288	42470311	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	-0.37106485497864733	[3,3]	[0,2]	-5	hSpCas9	positive selection	3013582
42466346	42466369	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGAGTGCACAGAAGCTGAGGG	PRICKLE1	ENSG00000139174	-0.05841155359798071	[3,3]	[2,2]	-1	hSpCas9	positive selection	3013583
42472388	42472411	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCTGGTCTCAGGCCCGGGGGG	PRICKLE1	ENSG00000139174	-0.013771785380551939	[3,3]	[1,3]	0	hSpCas9	positive selection	3013584
42469522	42469545	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGCAGGTGTTCAGTGCTCAGCGG	PRICKLE1	ENSG00000139174	0.41961020928231224	[2,2]	[2,3]	8	hSpCas9	positive selection	3013585
42470288	42470311	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	0.06865138991658491	[3,3]	[2,1]	1	hSpCas9	positive selection	3081440
42466346	42466369	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGAGTGCACAGAAGCTGAGGG	PRICKLE1	ENSG00000139174	-0.42007493591238115	[3,3]	[3,0]	-6	hSpCas9	positive selection	3081441
42472388	42472411	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCTGGTCTCAGGCCCGGGGGG	PRICKLE1	ENSG00000139174	-0.2423857852992569	[3,3]	[2,1]	-4	hSpCas9	positive selection	3081442
42469522	42469545	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGCAGGTGTTCAGTGCTCAGCGG	PRICKLE1	ENSG00000139174	-0.0856604828202649	[2,2]	[3,0]	-1	hSpCas9	positive selection	3081443
42472436	42472459		+	24336571	A375	resistance to PLX after 7 days	GCCAGAGTCATCATCTGATGTGG	PRICKLE1	ENSG00000139174	0.3611937258224547	[13,9]	[14,14]	8	hSpCas9	positive selection	3137706
42472412	42472435		-	24336571	A375	resistance to PLX after 7 days	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.23497904022736216	[2,3]	[2,2]	-7	hSpCas9	positive selection	3137707
42470245	42470268		-	24336571	A375	resistance to PLX after 7 days	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	-0.3837797168230872	[8,8]	[6,5]	-9	hSpCas9	positive selection	3137708
42470301	42470324		-	24336571	A375	resistance to PLX after 7 days	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.05163558262460208	[11,10]	[10,10]	-1	hSpCas9	positive selection	3137709
42472436	42472459		+	24336571	A375	resistance to PLX after 14 days	GCCAGAGTCATCATCTGATGTGG	PRICKLE1	ENSG00000139174	-0.4625748014100799	[18,13]	[3,5]	-5	hSpCas9	positive selection	3195499
42472412	42472435		-	24336571	A375	resistance to PLX after 14 days	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.21233352633216906	[6,2]	[1,1]	-2	hSpCas9	positive selection	3195500
42470245	42470268		-	24336571	A375	resistance to PLX after 14 days	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	-0.03605386940091415	[7,6]	[2,2]	0	hSpCas9	positive selection	3195501
42470301	42470324		-	24336571	A375	resistance to PLX after 14 days	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.31823018594571284	[10,8]	[3,2]	-4	hSpCas9	positive selection	3195502
42472436	42472459		+	24336571	A375	viability after 7 days	GCCAGAGTCATCATCTGATGTGG	PRICKLE1	ENSG00000139174	-0.017385441756914588	[11]	[13,9]	0	hSpCas9	negative selection	3253292
42472412	42472435		-	24336571	A375	viability after 7 days	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.05086731089123142	[3]	[2,3]	0	hSpCas9	negative selection	3253293
42470245	42470268		-	24336571	A375	viability after 7 days	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.19613996566023972	[7]	[8,8]	3	hSpCas9	negative selection	3253294
42470301	42470324		-	24336571	A375	viability after 7 days	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.7584420046932765	[19]	[11,10]	-8	hSpCas9	negative selection	3253295
42472436	42472459		+	24336571	A375	viability after 14 days	GCCAGAGTCATCATCTGATGTGG	PRICKLE1	ENSG00000139174	0.45301502003942956	[11]	[18,13]	6	hSpCas9	negative selection	3311085
42472412	42472435		-	24336571	A375	viability after 14 days	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.45939294148823406	[3]	[6,2]	6	hSpCas9	negative selection	3311086
42470245	42470268		-	24336571	A375	viability after 14 days	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	-0.022948266134146356	[7]	[7,6]	0	hSpCas9	negative selection	3311087
42470301	42470324		-	24336571	A375	viability after 14 days	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.9024592853041106	[19]	[10,8]	-8	hSpCas9	negative selection	3311088
42472437	42472460	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.2264895658184215	[178,178]	[0,0]	-1	hSpCas9	positive selection	3387421
42469459	42469482	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	1.7027373597681978	[46,46]	[0,0]	7	hSpCas9	positive selection	3387422
42469554	42469577	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.5362270227386499	[210,210]	[1,1]	2	hSpCas9	positive selection	3387423
42470288	42470311	12	-	26780180	HT29	viability (Avana library 4 designs)	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	0.118802505922604	[]	[]	0	hSpCas9	negative selection	3451767
42466346	42466369	12	-	26780180	HT29	viability (Avana library 4 designs)	GATGAGTGCACAGAAGCTGAGGG	PRICKLE1	ENSG00000139174	1.66994557695741	[]	[]	6	hSpCas9	negative selection	3451768
42472387	42472410	12	+	26780180	HT29	viability (Avana library 4 designs)	GCTCTGGTCTCAGGCCCGGGGGG	PRICKLE1	ENSG00000139174	1.20647305329807	[]	[]	5	hSpCas9	negative selection	3451769
42469522	42469545	12	-	26780180	HT29	viability (Avana library 4 designs)	TGCAGGTGTTCAGTGCTCAGCGG	PRICKLE1	ENSG00000139174	0.869722733009281	[]	[]	3	hSpCas9	negative selection	3451770
42472387	42472410	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCTGGTCTCAGGCCCGGGGGG	PRICKLE1	ENSG00000139174	4.87335369776692	[]	[]	8	hSpCas9	negative selection	3547820
42470288	42470311	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	-1.20664703573374	[]	[]	-1	hSpCas9	negative selection	3547821
42469522	42469545	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGCAGGTGTTCAGTGCTCAGCGG	PRICKLE1	ENSG00000139174	4.04778812807019	[]	[]	6	hSpCas9	negative selection	3547822
42466346	42466369	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGAGTGCACAGAAGCTGAGGG	PRICKLE1	ENSG00000139174	1.80105983758579	[]	[]	2	hSpCas9	negative selection	3547823
42468644	42468667	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	1.65186618303394	[]	[]	2	hSpCas9	negative selection	3547824
42472387	42472410	12	+	26780180	A375	viability (Avana lentiGuide)	GCTCTGGTCTCAGGCCCGGGGGG	PRICKLE1	ENSG00000139174	6.40822382206207	[]	[]	5	hSpCas9	negative selection	3656479
42470288	42470311	12	-	26780180	A375	viability (Avana lentiGuide)	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	2.23497099981553	[]	[]	2	hSpCas9	negative selection	3656480
42469522	42469545	12	-	26780180	A375	viability (Avana lentiGuide)	TGCAGGTGTTCAGTGCTCAGCGG	PRICKLE1	ENSG00000139174	-2.04777363072588	[]	[]	-3	hSpCas9	negative selection	3656481
42466346	42466369	12	-	26780180	A375	viability (Avana lentiGuide)	GATGAGTGCACAGAAGCTGAGGG	PRICKLE1	ENSG00000139174	8.71811758797639	[]	[]	6	hSpCas9	negative selection	3656482
42468644	42468667	12	-	26780180	A375	viability (Avana lentiGuide)	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	-4.25970725069506	[]	[]	-7	hSpCas9	negative selection	3656483
42472387	42472410	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCTGGTCTCAGGCCCGGGGGG	PRICKLE1	ENSG00000139174	0.38340417211015637	[4]	[5,5]	9	hSpCas9	positive selection	3765086
42470288	42470311	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	0.15916145829399045	[4]	[5,4]	4	hSpCas9	positive selection	3765087
42469522	42469545	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCAGGTGTTCAGTGCTCAGCGG	PRICKLE1	ENSG00000139174	0.30253492007924193	[4]	[5,5]	8	hSpCas9	positive selection	3765088
42466346	42466369	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGAGTGCACAGAAGCTGAGGG	PRICKLE1	ENSG00000139174	-0.018234980727667834	[5]	[5,3]	0	hSpCas9	positive selection	3765089
42468644	42468667	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.088635245646875	[5]	[5,5]	2	hSpCas9	positive selection	3765090
42472387	42472410	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCTGGTCTCAGGCCCGGGGGG	PRICKLE1	ENSG00000139174	-0.169810636987812	[5]	[3,4]	-2	hSpCas9	positive selection	3873693
42470288	42470311	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	-1.135760831990855	[5]	[1,1]	-8	hSpCas9	positive selection	3873694
42469522	42469545	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCAGGTGTTCAGTGCTCAGCGG	PRICKLE1	ENSG00000139174	-0.05656084918540155	[4]	[3,3]	-1	hSpCas9	positive selection	3873695
42466346	42466369	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGAGTGCACAGAAGCTGAGGG	PRICKLE1	ENSG00000139174	0.23512133571089186	[5]	[6,3]	6	hSpCas9	positive selection	3873696
42468644	42468667	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.3348263964023433	[5]	[5,5]	8	hSpCas9	positive selection	3873697
42469459	42469482	12	+	26780180	A375	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	1.1193281844485	[]	[]	5	hSpCas9	negative selection	3984136
42472412	42472435	12	-	26780180	A375	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.78670018251986	[]	[]	3	hSpCas9	negative selection	3984137
42470245	42470268	12	-	26780180	A375	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	-0.0272784951298722	[]	[]	-1	hSpCas9	negative selection	3984138
42470301	42470324	12	-	26780180	A375	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	1.77579235065602	[]	[]	9	hSpCas9	negative selection	3984139
42472437	42472460	12	-	26780180	A375	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	1.8905190282397	[]	[]	9	hSpCas9	negative selection	3984140
42469554	42469577	12	+	26780180	A375	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	1.48572636725449	[]	[]	8	hSpCas9	negative selection	3984141
42469459	42469482	12	+	26780180	HT29	viability (GeCKOv2 library)	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	1.78993612607503	[]	[]	8	hSpCas9	negative selection	4092102
42472412	42472435	12	-	26780180	HT29	viability (GeCKOv2 library)	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.874443275933783	[]	[]	3	hSpCas9	negative selection	4092103
42470245	42470268	12	-	26780180	HT29	viability (GeCKOv2 library)	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	1.16362692962524	[]	[]	5	hSpCas9	negative selection	4092104
42470301	42470324	12	-	26780180	HT29	viability (GeCKOv2 library)	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	1.7665622268201	[]	[]	8	hSpCas9	negative selection	4092105
42472437	42472460	12	-	26780180	HT29	viability (GeCKOv2 library)	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	2.39695796396767	[]	[]	9	hSpCas9	negative selection	4092106
42469554	42469577	12	+	26780180	HT29	viability (GeCKOv2 library)	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.867461190702782	[]	[]	3	hSpCas9	negative selection	4092107
42472436	42472459	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCAGAGTCATCATCTGATGTGG	PRICKLE1	ENSG00000139174	-0.13409468800172225	[3]	[1,2]	-3	hSpCas9	positive selection	4162855
42472412	42472435	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.6057060945615186	[2]	[0,0]	-9	hSpCas9	positive selection	4162856
42470245	42470268	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	-0.11329027579919992	[3]	[2,1]	-3	hSpCas9	positive selection	4162857
42470301	42470324	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.5568711789404408	[3]	[1,1]	-9	hSpCas9	positive selection	4162858
42472436	42472459	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCAGAGTCATCATCTGATGTGG	PRICKLE1	ENSG00000139174	0.27545993040043226	[2]	[5,0,0,0]	2	hSpCas9	positive selection	4226877
42472412	42472435	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	1.986086114105973	[1]	[2,0,4,3]	9	hSpCas9	positive selection	4226878
42470245	42470268	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	1.2180694998880939	[1]	[2,0,0,2]	8	hSpCas9	positive selection	4226879
42470301	42470324	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.123495393534859	[3]	[1,4,1,0]	1	hSpCas9	positive selection	4226880
42472412	42472435	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.37096465123664457	[1]	[1,0]	-7	hSpCas9	positive selection	4292105
42470301	42470324	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.47518304287947594	[3]	[1,1]	-8	hSpCas9	positive selection	4292106
42470245	42470268	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.07491746543185823	[3]	[3,1]	1	hSpCas9	positive selection	4292107
42472437	42472460	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.25164340355566106	[3]	[1,1]	-5	hSpCas9	positive selection	4356363
42469459	42469482	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.34573441234558355	[1]	[0,0]	-6	hSpCas9	positive selection	4356364
42469554	42469577	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.03161575385261137	[3]	[3,2]	0	hSpCas9	positive selection	4356365
42466294	42466316	12	+	27760321	OCIAML3	viability	CAGGACCGTTTCACACTCAAGG	PRICKLE1	ENSG00000139174	1.038623802843257	[451,359]	[518,816]	9	hSpCas9	negative selection	4430500
42470301	42470323	12	-	27760321	OCIAML3	viability	TTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.17873973283290728	[389,378]	[247,289]	-2	hSpCas9	negative selection	4430501
42466294	42466316	12	+	27760321	OCIAML2	viability	CAGGACCGTTTCACACTCAAGG	PRICKLE1	ENSG00000139174	0.3608454322240894	[451,359]	[363,491]	5	hSpCas9	negative selection	4513963
42470301	42470323	12	-	27760321	OCIAML2	viability	TTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.08219671950839291	[389,378]	[271,323]	-1	hSpCas9	negative selection	4513964
42466294	42466316	12	+	27760321	MV411	viability	CAGGACCGTTTCACACTCAAGG	PRICKLE1	ENSG00000139174	-0.3228257907454997	[451,359]	[108,368]	-2	hSpCas9	negative selection	4597426
42470301	42470323	12	-	27760321	MV411	viability	TTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.07372321328033088	[389,378]	[241,240]	0	hSpCas9	negative selection	4597427
42466294	42466316	12	+	27760321	HL60	viability	CAGGACCGTTTCACACTCAAGG	PRICKLE1	ENSG00000139174	-0.6653396578072203	[451,359]	[252,159]	-6	hSpCas9	negative selection	4680889
42470301	42470323	12	-	27760321	HL60	viability	TTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.213085161726872	[389,378]	[276,457]	2	hSpCas9	negative selection	4680890
42466294	42466316	12	+	27760321	HT1080	viability	CAGGACCGTTTCACACTCAAGG	PRICKLE1	ENSG00000139174	1.3964818893926791	[359,280]	[264,413]	7	hSpCas9	negative selection	4764352
42470301	42470323	12	-	27760321	HT1080	viability	TTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	1.1937076636580717	[378,295]	[255,363]	6	hSpCas9	negative selection	4764353
42466294	42466316	12	+	27760321	HT29	viability after 7 days	CAGGACCGTTTCACACTCAAGG	PRICKLE1	ENSG00000139174	0.4690619014637242	[359,280]	[640,558,521]	7	hSpCas9	negative selection	4847815
42470301	42470323	12	-	27760321	HT29	viability after 7 days	TTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.06179109234307999	[378,295]	[385,394,563]	0	hSpCas9	negative selection	4847816
42466294	42466316	12	+	27760321	HT29	viability after 25 days	CAGGACCGTTTCACACTCAAGG	PRICKLE1	ENSG00000139174	0.37705392013436956	[359,280]	[532,445,439]	4	hSpCas9	negative selection	4931278
42470301	42470323	12	-	27760321	HT29	viability after 25 days	TTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.2235187224657555	[378,295]	[424,156,410]	-2	hSpCas9	negative selection	4931279
42466294	42466316	12	+	27760321	HT29	viability after 22 days	CAGGACCGTTTCACACTCAAGG	PRICKLE1	ENSG00000139174	0.6295341350480461	[359,280]	[589,363,766]	7	hSpCas9	negative selection	5014741
42470301	42470323	12	-	27760321	HT29	viability after 22 days	TTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.02595723410068991	[378,295]	[481,280,383]	0	hSpCas9	negative selection	5014742
42466294	42466316	12	+	27760321	HT29	viability after 19 days	CAGGACCGTTTCACACTCAAGG	PRICKLE1	ENSG00000139174	1.0275272080329123	[359,280]	[855,312,1070]	9	hSpCas9	negative selection	5098204
42470301	42470323	12	-	27760321	HT29	viability after 19 days	TTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.6097242878290356	[378,295]	[474,242,70]	-5	hSpCas9	negative selection	5098205
42466294	42466316	12	+	27760321	HT29	viability after 16 days	CAGGACCGTTTCACACTCAAGG	PRICKLE1	ENSG00000139174	0.11949207972956695	[359,280]	[308,387,463]	1	hSpCas9	negative selection	5181667
42470301	42470323	12	-	27760321	HT29	viability after 16 days	TTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.6825349242215296	[378,295]	[301,85,327]	-6	hSpCas9	negative selection	5181668
42466294	42466316	12	+	27760321	HT29	viability after 13 days	CAGGACCGTTTCACACTCAAGG	PRICKLE1	ENSG00000139174	-0.09444042417200449	[359,280]	[386,332,325]	-1	hSpCas9	negative selection	5265130
42470301	42470323	12	-	27760321	HT29	viability after 13 days	TTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.08465530014954321	[378,295]	[562,273,275]	-1	hSpCas9	negative selection	5265131
42466294	42466316	12	+	27760321	HT29	viability after 10 days	CAGGACCGTTTCACACTCAAGG	PRICKLE1	ENSG00000139174	0.1426527457349624	[359,280]	[424,264,625]	1	hSpCas9	negative selection	5348593
42470301	42470323	12	-	27760321	HT29	viability after 10 days	TTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.4605839195752115	[378,295]	[306,312,298]	-5	hSpCas9	negative selection	5348594
42466294	42466316	12	+	27760321	MOLM13	viability	CAGGACCGTTTCACACTCAAGG	PRICKLE1	ENSG00000139174	0.8982622182011745	[451,359]	[479,376]	6	hSpCas9	negative selection	5432056
42470301	42470323	12	-	27760321	MOLM13	viability	TTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	1.0090736390398427	[389,378]	[221,620]	7	hSpCas9	negative selection	5432057
42589353	42589376	12	+	27661255	K562	viability	GACTCCGGCGGTGCCAGCGAAGG	PRICKLE1	ENSG00000139174	0.13053546762751278	[495,524]	[466,427]	4	dCas9-KRAB	negative selection	5504073
42589676	42589699	12	+	27661255	K562	viability	GTTCCGGGCGCGCTGTCGGGCGG	PRICKLE1	ENSG00000139174	0.24310443624145317	[280,436]	[346,327]	7	dCas9-KRAB	negative selection	5504074
42589731	42589754	12	+	27661255	K562	viability	GCTGCAGGCGGAGTGCGCTCGGG	PRICKLE1	ENSG00000139174	-0.1766809418276707	[95,89]	[81,51]	-5	dCas9-KRAB	negative selection	5504075
42589313	42589336	12	-	27661255	K562	viability	GTCGGTGTCGCAGAAGATCAGGG	PRICKLE1	ENSG00000139174	0.22496415641354228	[909,1006]	[1011,791]	7	dCas9-KRAB	negative selection	5504076
42589366	42589389	12	-	27661255	K562	viability	GTAGGGCCGGGCACCTTCGCTGG	PRICKLE1	ENSG00000139174	0.13066447386005536	[909,866]	[781,773]	4	dCas9-KRAB	negative selection	5504077
42472412	42472435	12	-	27260156	BXPC3	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.3273901689909935	[136]	[135,127,212,258]	7	hSpCas9	negative selection	5564565
42470301	42470324	12	-	27260156	BXPC3	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.03495760338772519	[611]	[649,729,620,605]	0	hSpCas9	negative selection	5564566
42470245	42470268	12	-	27260156	BXPC3	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.18273465920918192	[582]	[611,514,686,1006]	4	hSpCas9	negative selection	5564567
42472437	42472460	12	-	27260156	BXPC3	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	0.05674729987259809	[459]	[402,385,499,757]	1	hSpCas9	negative selection	5628823
42469459	42469482	12	+	27260156	BXPC3	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	0.11748029705540741	[153]	[278,151,76,177]	2	hSpCas9	negative selection	5628824
42469554	42469577	12	+	27260156	BXPC3	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.2377211154025976	[640]	[744,651,944,834]	5	hSpCas9	negative selection	5628825
42472412	42472435	12	-	27260156	A673	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.16277995953317625	[136]	[232,131,195,181]	4	hSpCas9	negative selection	5685816
42470301	42470324	12	-	27260156	A673	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.1405375551461167	[611]	[864,786,749,845]	3	hSpCas9	negative selection	5685817
42470245	42470268	12	-	27260156	A673	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.07167669574616359	[582]	[802,753,747,637]	1	hSpCas9	negative selection	5685818
42472437	42472460	12	-	27260156	A673	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.361957880571363	[459]	[482,326,421,498]	-7	hSpCas9	negative selection	5750074
42469459	42469482	12	+	27260156	A673	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.25244680217872006	[153]	[103,174,178,155]	-6	hSpCas9	negative selection	5750075
42469554	42469577	12	+	27260156	A673	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.34633740928964524	[640]	[1178,944,737,1081]	7	hSpCas9	negative selection	5750076
42472412	42472435	12	-	27260156	A375	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.005213529363967906	[136]	[143,139,187,161]	0	hSpCas9	negative selection	5807067
42470301	42470324	12	-	27260156	A375	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.005463706588894557	[611]	[747,834,724,571]	0	hSpCas9	negative selection	5807068
42470245	42470268	12	-	27260156	A375	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.11609362523973565	[582]	[514,1011,742,717]	1	hSpCas9	negative selection	5807069
42472437	42472460	12	-	27260156	A375	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.24536292540383242	[459]	[381,419,466,527]	-4	hSpCas9	negative selection	5871325
42469459	42469482	12	+	27260156	A375	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.019387912884427427	[153]	[176,163,185,179]	0	hSpCas9	negative selection	5871326
42469554	42469577	12	+	27260156	A375	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.2730096801002983	[640]	[693,1062,1051,834]	4	hSpCas9	negative selection	5871327
42472412	42472435	12	-	27260156	COLO741	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.0270439994102305	[136]	[195,145,192]	0	hSpCas9	negative selection	5928318
42470301	42470324	12	-	27260156	COLO741	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.023082744025549662	[611]	[906,811,680]	0	hSpCas9	negative selection	5928319
42470245	42470268	12	-	27260156	COLO741	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.10095086063889236	[582]	[1023,708,688]	2	hSpCas9	negative selection	5928320
42472437	42472460	12	-	27260156	COLO741	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.3679493809371432	[459]	[510,446,414]	-7	hSpCas9	negative selection	5992576
42469459	42469482	12	+	27260156	COLO741	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	0.6255651967844991	[153]	[109,75,678]	9	hSpCas9	negative selection	5992577
42469554	42469577	12	+	27260156	COLO741	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.17506909459049996	[640]	[1048,860,875]	4	hSpCas9	negative selection	5992578
42472412	42472435	12	-	27260156	CAL120	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.6468352549820224	[136]	[515,102,219]	8	hSpCas9	negative selection	6049569
42470301	42470324	12	-	27260156	CAL120	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.22930220337145185	[611]	[1138,629,944]	3	hSpCas9	negative selection	6049570
42470245	42470268	12	-	27260156	CAL120	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.2885511374975596	[582]	[1332,662,731]	4	hSpCas9	negative selection	6049571
42472437	42472460	12	-	27260156	CAL120	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.4655361717040516	[459]	[389,391,456]	-6	hSpCas9	negative selection	6113827
42469459	42469482	12	+	27260156	CAL120	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-1.164546019237555	[153]	[47,72,128]	-9	hSpCas9	negative selection	6113828
42469554	42469577	12	+	27260156	CAL120	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.16963303947401448	[640]	[731,1019,913]	2	hSpCas9	negative selection	6113829
42472412	42472435	12	-	27260156	CADOES1	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.7377324117174957	[136]	[214,188,152,295]	9	hSpCas9	negative selection	6170820
42470301	42470324	12	-	27260156	CADOES1	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.12386415900589187	[611]	[438,536,506,609]	-2	hSpCas9	negative selection	6170821
42470245	42470268	12	-	27260156	CADOES1	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.11669917398909063	[582]	[448,621,540,745]	2	hSpCas9	negative selection	6170822
42472437	42472460	12	-	27260156	CADOES1	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	0.3023326133249097	[459]	[679,372,466,591]	5	hSpCas9	negative selection	6235078
42469459	42469482	12	+	27260156	CADOES1	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.6654808247365553	[153]	[78,81,89,110]	-8	hSpCas9	negative selection	6235079
42469554	42469577	12	+	27260156	CADOES1	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.3455800135213409	[640]	[589,830,919,686]	6	hSpCas9	negative selection	6235080
42472412	42472435	12	-	27260156	EWS502	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.18761819253382117	[136]	[87,85,212,129]	-3	hSpCas9	negative selection	6292071
42470301	42470324	12	-	27260156	EWS502	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.1634255318951811	[611]	[601,835,633,846]	3	hSpCas9	negative selection	6292072
42470245	42470268	12	-	27260156	EWS502	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.042323246639189904	[582]	[485,606,740,734]	0	hSpCas9	negative selection	6292073
42472437	42472460	12	-	27260156	EWS502	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	0.0031529137732188676	[459]	[562,471,496,404]	0	hSpCas9	negative selection	6356329
42469459	42469482	12	+	27260156	EWS502	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.24537134401595706	[153]	[200,136,100,99]	-4	hSpCas9	negative selection	6356330
42469554	42469577	12	+	27260156	EWS502	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.37659602285315746	[640]	[973,906,844,775]	6	hSpCas9	negative selection	6356331
42472412	42472435	12	-	27260156	EW8	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.15256705158661976	[136]	[156,119,68,64]	-3	hSpCas9	negative selection	6413322
42470301	42470324	12	-	27260156	EW8	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.05031492428595313	[611]	[617,531,439,486]	0	hSpCas9	negative selection	6413323
42470245	42470268	12	-	27260156	EW8	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.16579228431191173	[582]	[438,630,463,585]	3	hSpCas9	negative selection	6413324
42472437	42472460	12	-	27260156	EW8	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.2737090930392402	[459]	[418,291,235,309]	-5	hSpCas9	negative selection	6477580
42469459	42469482	12	+	27260156	EW8	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.04522604100646088	[153]	[38,181,166,78]	-1	hSpCas9	negative selection	6477581
42469554	42469577	12	+	27260156	EW8	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.35337560625143855	[640]	[702,676,598,688]	6	hSpCas9	negative selection	6477582
42472412	42472435	12	-	27260156	CORL105	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.6448869428210227	[136]	[304,197,194,298]	9	hSpCas9	negative selection	6534573
42470301	42470324	12	-	27260156	CORL105	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.28450069414270324	[611]	[753,761,938,1042]	5	hSpCas9	negative selection	6534574
42470245	42470268	12	-	27260156	CORL105	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.20649489692210626	[582]	[778,737,866,778]	4	hSpCas9	negative selection	6534575
42472437	42472460	12	-	27260156	CORL105	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	0.2632577324059335	[459]	[770,587,597,625]	5	hSpCas9	negative selection	6598831
42469459	42469482	12	+	27260156	CORL105	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.2889891778784146	[153]	[170,110,180,133]	-5	hSpCas9	negative selection	6598832
42469554	42469577	12	+	27260156	CORL105	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.2348170128553338	[640]	[1118,710,922,796]	4	hSpCas9	negative selection	6598833
42472412	42472435	12	-	27260156	HS294T	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.2810510258857808	[136]	[39,94,36,90]	4	hSpCas9	negative selection	6655824
42470301	42470324	12	-	27260156	HS294T	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.04311370944898835	[611]	[177,199,255,301]	0	hSpCas9	negative selection	6655825
42470245	42470268	12	-	27260156	HS294T	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.18008911934936395	[582]	[220,220,313,271]	2	hSpCas9	negative selection	6655826
42472437	42472460	12	-	27260156	HS294T	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.22863189435377818	[459]	[140,71,127,292]	-3	hSpCas9	negative selection	6720082
42469459	42469482	12	+	27260156	HS294T	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	0.13925775623955405	[153]	[38,101,33,92]	2	hSpCas9	negative selection	6720083
42469554	42469577	12	+	27260156	HS294T	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.3890044287722309	[640]	[321,215,308,479]	5	hSpCas9	negative selection	6720084
42472412	42472435	12	-	27260156	HCC44	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.4048683249866818	[136]	[204,195,285,148]	6	hSpCas9	negative selection	6777075
42470301	42470324	12	-	27260156	HCC44	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.021667589038701418	[611]	[712,543,1068,569]	0	hSpCas9	negative selection	6777076
42470245	42470268	12	-	27260156	HCC44	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	-0.0266374597105567	[582]	[541,518,988,602]	0	hSpCas9	negative selection	6777077
42472437	42472460	12	-	27260156	HCC44	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.1722932167368861	[459]	[520,313,637,427]	-3	hSpCas9	negative selection	6841333
42469459	42469482	12	+	27260156	HCC44	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	0.06900834277604861	[153]	[129,186,179,224]	1	hSpCas9	negative selection	6841334
42469554	42469577	12	+	27260156	HCC44	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.10607186669093743	[640]	[646,816,800,833]	1	hSpCas9	negative selection	6841335
42472412	42472435	12	-	27260156	G402	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.8813088841968671	[136]	[185,652,234,165]	9	hSpCas9	negative selection	6898326
42470301	42470324	12	-	27260156	G402	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.6276440229912361	[611]	[1429,1421,869,953]	7	hSpCas9	negative selection	6898327
42470245	42470268	12	-	27260156	G402	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	-0.10746585625300914	[582]	[715,443,852,622]	-1	hSpCas9	negative selection	6898328
42472437	42472460	12	-	27260156	G402	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	0.1416967396617999	[459]	[1076,785,464,240]	1	hSpCas9	negative selection	6962584
42469459	42469482	12	+	27260156	G402	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	1.0148168008431824	[153]	[503,86,223,687]	9	hSpCas9	negative selection	6962585
42469554	42469577	12	+	27260156	G402	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.36535595967955864	[640]	[1576,744,1286,508]	4	hSpCas9	negative selection	6962586
42472412	42472435	12	-	27260156	L33	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.026009440756134206	[136]	[92,63,122,94]	0	hSpCas9	negative selection	7019577
42470301	42470324	12	-	27260156	L33	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.2525403426919429	[611]	[504,181,340,562]	-5	hSpCas9	negative selection	7019578
42470245	42470268	12	-	27260156	L33	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.06377898650328745	[582]	[651,236,362,627]	1	hSpCas9	negative selection	7019579
42472437	42472460	12	-	27260156	L33	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.21066953399946498	[459]	[322,166,196,545]	-5	hSpCas9	negative selection	7083835
42469459	42469482	12	+	27260156	L33	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.20143042771549258	[153]	[84,76,96,109]	-4	hSpCas9	negative selection	7083836
42469554	42469577	12	+	27260156	L33	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.0024041656559745106	[640]	[552,290,421,635]	0	hSpCas9	negative selection	7083837
42472412	42472435	12	-	27260156	K562	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.7293378192226472	[136]	[241,223,218,132]	8	hSpCas9	negative selection	7140828
42470301	42470324	12	-	27260156	K562	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.16350145995101145	[611]	[755,807,477,431]	2	hSpCas9	negative selection	7140829
42470245	42470268	12	-	27260156	K562	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.1402215801149267	[582]	[276,756,526,688]	1	hSpCas9	negative selection	7140830
42472437	42472460	12	-	27260156	K562	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.4617875896512777	[459]	[319,266,435,175]	-5	hSpCas9	negative selection	7205086
42469459	42469482	12	+	27260156	K562	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.6571112721542749	[153]	[34,51,69,172]	-6	hSpCas9	negative selection	7205087
42469554	42469577	12	+	27260156	K562	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.4350327039227721	[640]	[690,798,949,642]	5	hSpCas9	negative selection	7205088
42472412	42472435	12	-	27260156	HT29	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.08674639635095871	[136]	[216,173,180,70]	-2	hSpCas9	negative selection	7262079
42470301	42470324	12	-	27260156	HT29	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.23149142262145822	[611]	[812,1114,706,868]	4	hSpCas9	negative selection	7262080
42470245	42470268	12	-	27260156	HT29	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.2108422856330458	[582]	[745,1070,673,801]	4	hSpCas9	negative selection	7262081
42472437	42472460	12	-	27260156	HT29	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	0.01007615120743097	[459]	[553,490,539,645]	0	hSpCas9	negative selection	7326337
42469459	42469482	12	+	27260156	HT29	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.2911904933826579	[153]	[205,252,51,116]	-5	hSpCas9	negative selection	7326338
42469554	42469577	12	+	27260156	HT29	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.41217832147045524	[640]	[1144,945,1106,952]	7	hSpCas9	negative selection	7326339
42472412	42472435	12	-	27260156	MHHES1	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.3463781311232381	[136]	[315,138,286,75]	6	hSpCas9	negative selection	7383330
42470301	42470324	12	-	27260156	MHHES1	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.4474106470814641	[611]	[1461,814,833,726]	7	hSpCas9	negative selection	7383331
42470245	42470268	12	-	27260156	MHHES1	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.17567608866485573	[582]	[703,767,706,762]	3	hSpCas9	negative selection	7383332
42472437	42472460	12	-	27260156	MHHES1	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.17393013363956292	[459]	[516,447,413,453]	-3	hSpCas9	negative selection	7447588
42469459	42469482	12	+	27260156	MHHES1	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	0.4481159452449619	[153]	[213,244,161,301]	7	hSpCas9	negative selection	7447589
42469554	42469577	12	+	27260156	MHHES1	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.28395929233026224	[640]	[1067,814,1042,642]	5	hSpCas9	negative selection	7447590
42472412	42472435	12	-	27260156	MEWO	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.23658558564200782	[136]	[132,113,83]	-5	hSpCas9	negative selection	7504581
42470301	42470324	12	-	27260156	MEWO	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.14229909225552656	[611]	[756,599,562]	3	hSpCas9	negative selection	7504582
42470245	42470268	12	-	27260156	MEWO	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.07871180036700048	[582]	[687,497,563]	1	hSpCas9	negative selection	7504583
42472437	42472460	12	-	27260156	MEWO	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.2605172521842247	[459]	[342,265,465]	-5	hSpCas9	negative selection	7568839
42469459	42469482	12	+	27260156	MEWO	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	0.5051378895703529	[153]	[229,274,112]	8	hSpCas9	negative selection	7568840
42469554	42469577	12	+	27260156	MEWO	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.09186334613409591	[640]	[770,592,578]	2	hSpCas9	negative selection	7568841
42472412	42472435	12	-	27260156	LNCAPCLONEFGC	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.20505293688557602	[136]	[133,127,167,146]	3	hSpCas9	negative selection	7625832
42470301	42470324	12	-	27260156	LNCAPCLONEFGC	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.10274127316991438	[611]	[492,631,794,489]	1	hSpCas9	negative selection	7625833
42470245	42470268	12	-	27260156	LNCAPCLONEFGC	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.14524317963611522	[582]	[452,593,666,635]	2	hSpCas9	negative selection	7625834
42472437	42472460	12	-	27260156	LNCAPCLONEFGC	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	0.2932322132894024	[459]	[370,452,647,596]	4	hSpCas9	negative selection	7690090
42469459	42469482	12	+	27260156	LNCAPCLONEFGC	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.05813932729808102	[153]	[96,75,184,189]	-1	hSpCas9	negative selection	7690091
42469554	42469577	12	+	27260156	LNCAPCLONEFGC	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.45149585546462184	[640]	[654,687,1007,865]	7	hSpCas9	negative selection	7690092
42472412	42472435	12	-	27260156	PANC0327	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.6971579006790933	[136]	[506,154,114,42]	8	hSpCas9	negative selection	7747083
42470301	42470324	12	-	27260156	PANC0327	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.013008377091432655	[611]	[727,430,539,524]	0	hSpCas9	negative selection	7747084
42470245	42470268	12	-	27260156	PANC0327	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.44940967477984234	[582]	[1401,435,440,640]	6	hSpCas9	negative selection	7747085
42472437	42472460	12	-	27260156	PANC0327	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	0.04550769485176576	[459]	[405,664,329,252]	0	hSpCas9	negative selection	7811341
42469459	42469482	12	+	27260156	PANC0327	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-1.0901593165942491	[153]	[141,43,52,26]	-8	hSpCas9	negative selection	7811342
42469554	42469577	12	+	27260156	PANC0327	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	-0.08084549561672194	[640]	[752,513,455,450]	-1	hSpCas9	negative selection	7811343
42472412	42472435	12	-	27260156	NCIH2009	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.3623542348701809	[136]	[343,197,215]	5	hSpCas9	negative selection	7868334
42470301	42470324	12	-	27260156	NCIH2009	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.10692571880696727	[611]	[835,732,820]	-1	hSpCas9	negative selection	7868335
42470245	42470268	12	-	27260156	NCIH2009	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.2189106358992297	[582]	[922,918,995]	3	hSpCas9	negative selection	7868336
42472437	42472460	12	-	27260156	NCIH2009	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.6746966321257928	[459]	[471,341,407]	-7	hSpCas9	negative selection	7932592
42469459	42469482	12	+	27260156	NCIH2009	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	0.17442980926933127	[153]	[109,450,136]	2	hSpCas9	negative selection	7932593
42469554	42469577	12	+	27260156	NCIH2009	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	-0.09658469768079492	[640]	[772,1088,631]	-1	hSpCas9	negative selection	7932594
42472412	42472435	12	-	27260156	NCIH1373	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.07203294543382133	[136]	[263,151,167,18]	0	hSpCas9	negative selection	7989585
42470301	42470324	12	-	27260156	NCIH1373	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.46196005154428554	[611]	[569,154,660,172]	-4	hSpCas9	negative selection	7989586
42470245	42470268	12	-	27260156	NCIH1373	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	-0.06622394242581009	[582]	[721,741,467,147]	0	hSpCas9	negative selection	7989587
42472437	42472460	12	-	27260156	NCIH1373	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.3661096850242238	[459]	[661,230,466,75]	-4	hSpCas9	negative selection	8053843
42469459	42469482	12	+	27260156	NCIH1373	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-1.1399481302638679	[153]	[33,198,23,8]	-8	hSpCas9	negative selection	8053844
42469554	42469577	12	+	27260156	NCIH1373	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.1916576802333944	[640]	[525,1426,339,232]	2	hSpCas9	negative selection	8053845
42472412	42472435	12	-	27260156	PATU8902	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.45202948312859603	[136]	[134,128,154,132]	-4	hSpCas9	negative selection	8110836
42470301	42470324	12	-	27260156	PATU8902	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.22366064915760392	[611]	[1537,722,723,1057]	2	hSpCas9	negative selection	8110837
42470245	42470268	12	-	27260156	PATU8902	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.17250486646850888	[582]	[771,1300,762,851]	1	hSpCas9	negative selection	8110838
42472437	42472460	12	-	27260156	PATU8902	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	0.2510732088372755	[459]	[777,955,675,641]	2	hSpCas9	negative selection	8175094
42469459	42469482	12	+	27260156	PATU8902	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	0.3022620585979605	[153]	[295,51,154,622]	3	hSpCas9	negative selection	8175095
42469554	42469577	12	+	27260156	PATU8902	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.35760149509754063	[640]	[978,992,741,2068]	3	hSpCas9	negative selection	8175096
42472412	42472435	12	-	27260156	PANC1	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.18758391597105217	[136]	[108,256,111,88]	3	hSpCas9	negative selection	8232087
42470301	42470324	12	-	27260156	PANC1	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.1851070939433889	[611]	[491,389,585,373]	-3	hSpCas9	negative selection	8232088
42470245	42470268	12	-	27260156	PANC1	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.12447132701933311	[582]	[614,759,520,352]	2	hSpCas9	negative selection	8232089
42472437	42472460	12	-	27260156	PANC1	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	0.040692013596810656	[459]	[518,410,410,294]	0	hSpCas9	negative selection	8296345
42469459	42469482	12	+	27260156	PANC1	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	0.5547819697289404	[153]	[224,116,157,247]	8	hSpCas9	negative selection	8296346
42469554	42469577	12	+	27260156	PANC1	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.2995475789536048	[640]	[668,831,809,457]	5	hSpCas9	negative selection	8296347
42472412	42472435	12	-	27260156	PANC0813	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.27825987839648403	[136]	[134,171,149,76]	-4	hSpCas9	negative selection	8353338
42470301	42470324	12	-	27260156	PANC0813	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.014834919641669109	[611]	[814,707,800,595]	0	hSpCas9	negative selection	8353339
42470245	42470268	12	-	27260156	PANC0813	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.2825051125216295	[582]	[897,978,722,740]	4	hSpCas9	negative selection	8353340
42472437	42472460	12	-	27260156	PANC0813	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.03292762398416143	[459]	[528,574,607,406]	0	hSpCas9	negative selection	8417596
42469459	42469482	12	+	27260156	PANC0813	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.765529797594158	[153]	[132,122,35,133]	-8	hSpCas9	negative selection	8417597
42469554	42469577	12	+	27260156	PANC0813	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	-0.22198631621173567	[640]	[501,610,711,737]	-4	hSpCas9	negative selection	8417598
42472412	42472435	12	-	27260156	RDES	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.13881291940088425	[136]	[117,137,232,225]	2	hSpCas9	negative selection	8474589
42470301	42470324	12	-	27260156	RDES	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.16099502379836922	[611]	[551,865,909,854]	2	hSpCas9	negative selection	8474590
42470245	42470268	12	-	27260156	RDES	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	-0.22204076616461493	[582]	[541,542,569,645]	-4	hSpCas9	negative selection	8474591
42472437	42472460	12	-	27260156	RDES	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.24828083159834663	[459]	[420,383,488,492]	-4	hSpCas9	negative selection	8538847
42469459	42469482	12	+	27260156	RDES	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.23087515302841322	[153]	[167,134,101,195]	-4	hSpCas9	negative selection	8538848
42469554	42469577	12	+	27260156	RDES	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.24050411742247274	[640]	[794,720,966,1031]	4	hSpCas9	negative selection	8538849
42472412	42472435	12	-	27260156	PC3	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.2838376053022018	[136]	[143,165,173,171]	6	hSpCas9	negative selection	8595840
42470301	42470324	12	-	27260156	PC3	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.07633316004761881	[611]	[333,395,1491,512]	-2	hSpCas9	negative selection	8595841
42470245	42470268	12	-	27260156	PC3	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.08364363712668871	[582]	[251,669,1282,633]	2	hSpCas9	negative selection	8595842
42472437	42472460	12	-	27260156	PC3	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.12128757167038007	[459]	[323,376,580,463]	-3	hSpCas9	negative selection	8660098
42469459	42469482	12	+	27260156	PC3	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.2817526751240509	[153]	[95,152,93,146]	-6	hSpCas9	negative selection	8660099
42469554	42469577	12	+	27260156	PC3	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.43820258123981354	[640]	[530,937,1136,1027]	8	hSpCas9	negative selection	8660100
42472412	42472435	12	-	27260156	PATU8988T	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.16862990520864685	[136]	[103,272,127,97]	3	hSpCas9	negative selection	8717091
42470301	42470324	12	-	27260156	PATU8988T	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.5731483165684079	[611]	[1155,753,803,786]	8	hSpCas9	negative selection	8717092
42470245	42470268	12	-	27260156	PATU8988T	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.08291088481418357	[582]	[395,743,764,483]	1	hSpCas9	negative selection	8717093
42472437	42472460	12	-	27260156	PATU8988T	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.1544432817512048	[459]	[445,372,398,374]	-3	hSpCas9	negative selection	8781349
42469459	42469482	12	+	27260156	PATU8988T	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.7438898088633723	[153]	[41,80,33,207]	-8	hSpCas9	negative selection	8781350
42469554	42469577	12	+	27260156	PATU8988T	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	-0.08259561767298945	[640]	[452,672,451,787]	-1	hSpCas9	negative selection	8781351
42472412	42472435	12	-	27260156	T47D	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.3838252736563643	[136]	[261,120,230,226]	7	hSpCas9	negative selection	8838342
42470301	42470324	12	-	27260156	T47D	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.03144932868407457	[611]	[632,719,774,787]	0	hSpCas9	negative selection	8838343
42470245	42470268	12	-	27260156	T47D	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.13039901392642328	[582]	[687,660,706,930]	2	hSpCas9	negative selection	8838344
42472437	42472460	12	-	27260156	T47D	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.06124391426140808	[459]	[570,478,450,558]	-1	hSpCas9	negative selection	8902600
42469459	42469482	12	+	27260156	T47D	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.36137975588623616	[153]	[180,135,115,125]	-6	hSpCas9	negative selection	8902601
42469554	42469577	12	+	27260156	T47D	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.12010007443613785	[640]	[907,735,802,805]	2	hSpCas9	negative selection	8902602
42472412	42472435	12	-	27260156	SU8686	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.43236009693898225	[136]	[100,165,181,315]	7	hSpCas9	negative selection	8959593
42470301	42470324	12	-	27260156	SU8686	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.0750667148480178	[611]	[473,639,646,842]	1	hSpCas9	negative selection	8959594
42470245	42470268	12	-	27260156	SU8686	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.17738822922819464	[582]	[612,525,763,745]	3	hSpCas9	negative selection	8959595
42472437	42472460	12	-	27260156	SU8686	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.021921179077156204	[459]	[359,327,508,657]	0	hSpCas9	negative selection	9023851
42469459	42469482	12	+	27260156	SU8686	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-1.1110196463580346	[153]	[62,56,60,109]	-8	hSpCas9	negative selection	9023852
42469554	42469577	12	+	27260156	SU8686	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.3095486101209564	[640]	[788,665,901,809]	5	hSpCas9	negative selection	9023853
42472412	42472435	12	-	27260156	SKES1	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.0625821989132842	[136]	[130,115,140,131]	-1	hSpCas9	negative selection	9080844
42470301	42470324	12	-	27260156	SKES1	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.12966954308392198	[611]	[678,484,546,526]	-3	hSpCas9	negative selection	9080845
42470245	42470268	12	-	27260156	SKES1	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	-0.22346046793958294	[582]	[662,500,460,397]	-5	hSpCas9	negative selection	9080846
42472437	42472460	12	-	27260156	SKES1	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.37881999823686996	[459]	[524,351,342,226]	-7	hSpCas9	negative selection	9145102
42469459	42469482	12	+	27260156	SKES1	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.7586576228980475	[153]	[91,97,109,65]	-9	hSpCas9	negative selection	9145103
42469554	42469577	12	+	27260156	SKES1	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	-0.008337598512104416	[640]	[605,647,701,582]	0	hSpCas9	negative selection	9145104
42472412	42472435	12	-	27260156	TOV112D	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	0.4595718841778429	[136]	[316,180,172,94]	8	hSpCas9	negative selection	9202095
42470301	42470324	12	-	27260156	TOV112D	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	-0.08878217738191713	[611]	[569,790,571,427]	-2	hSpCas9	negative selection	9202096
42470245	42470268	12	-	27260156	TOV112D	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	-0.3089603872397582	[582]	[732,404,487,269]	-6	hSpCas9	negative selection	9202097
42472437	42472460	12	-	27260156	TOV112D	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.3209224517828909	[459]	[392,537,313,275]	-6	hSpCas9	negative selection	9266353
42469459	42469482	12	+	27260156	TOV112D	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	0.2131248884331931	[153]	[101,71,360,147]	4	hSpCas9	negative selection	9266354
42469554	42469577	12	+	27260156	TOV112D	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.14919440618633023	[640]	[947,790,546,602]	3	hSpCas9	negative selection	9266355
42472412	42472435	12	-	27260156	TC71	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.09900830095305935	[136]	[182,145,94,123]	-3	hSpCas9	negative selection	9323346
42470301	42470324	12	-	27260156	TC71	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.0392360101414409	[611]	[801,708,471,719]	1	hSpCas9	negative selection	9323347
42470245	42470268	12	-	27260156	TC71	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.17405499854859968	[582]	[593,701,658,879]	4	hSpCas9	negative selection	9323348
42472437	42472460	12	-	27260156	TC71	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	-0.0827976752900337	[459]	[456,552,478,366]	-2	hSpCas9	negative selection	9387604
42469459	42469482	12	+	27260156	TC71	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.1563576164792626	[153]	[168,134,122,166]	-4	hSpCas9	negative selection	9387605
42469554	42469577	12	+	27260156	TC71	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.16089543825841018	[640]	[793,721,741,817]	4	hSpCas9	negative selection	9387606
42472412	42472435	12	-	27260156	TC32	viability	GTGCATTGGAGGAGTACGCCTGG	PRICKLE1	ENSG00000139174	-0.12285833811350866	[136]	[147,13,164,187]	-2	hSpCas9	negative selection	9444597
42470301	42470324	12	-	27260156	TC32	viability	GTTCCTTACGTTAACAGCCCCGG	PRICKLE1	ENSG00000139174	0.1961332235735616	[611]	[567,584,869,646]	3	hSpCas9	negative selection	9444598
42470245	42470268	12	-	27260156	TC32	viability	GTTACCACCACATGATAATGAGG	PRICKLE1	ENSG00000139174	0.11957176483443416	[582]	[364,464,857,794]	2	hSpCas9	negative selection	9444599
42472437	42472460	12	-	27260156	TC32	viability	TCCACATCAGATGATGACTCTGG	PRICKLE1	ENSG00000139174	0.1899005736454491	[459]	[392,452,670,482]	3	hSpCas9	negative selection	9508855
42469459	42469482	12	+	27260156	TC32	viability	CACAGCATGCATGACTGCTCTGG	PRICKLE1	ENSG00000139174	-0.006792020383529884	[153]	[122,148,192,108]	0	hSpCas9	negative selection	9508856
42469554	42469577	12	+	27260156	TC32	viability	TCTCCTCTTCACTCAAAGACTGG	PRICKLE1	ENSG00000139174	0.40518109974265476	[640]	[598,679,1213,791]	7	hSpCas9	negative selection	9508857
42468644	42468667	12	-	27869803	HPAFII	viability after 27 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.754347877691302	[788]	[858,566,NaN]	6	hSpCas9	negative selection	9546644
42469557	42469580	12	-	27869803	HPAFII	viability after 27 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.1309384767909073	[432]	[335,176,NaN]	1	hSpCas9	negative selection	9546645
42472385	42472408	12	+	27869803	HPAFII	viability after 27 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-1.950720525131464	[376]	[83,23,NaN]	-8	hSpCas9	negative selection	9546646
42468644	42468667	12	-	27869803	HPAFII	viability after 15 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.29227999874792543	[788]	[1654,654,NaN]	3	hSpCas9	negative selection	9629093
42469557	42469580	12	-	27869803	HPAFII	viability after 15 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.2960687233051774	[432]	[891,371,NaN]	3	hSpCas9	negative selection	9629094
42472385	42472408	12	+	27869803	HPAFII	viability after 15 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.6543128732224743	[376]	[307,225,NaN]	-6	hSpCas9	negative selection	9629095
42468644	42468667	12	-	27869803	ASPC1	viability after 36 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.545447150923599	[2255]	[1536,1150,863]	5	hSpCas9	negative selection	9711542
42469557	42469580	12	-	27869803	ASPC1	viability after 36 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.4485839993573928	[1285]	[576,957,356]	4	hSpCas9	negative selection	9711543
42472385	42472408	12	+	27869803	ASPC1	viability after 36 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	0.2819246444079895	[1161]	[514,852,186]	3	hSpCas9	negative selection	9711544
42468644	42468667	12	-	27869803	PATU8988S	viability after 35 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.4888645491508994	[1787]	[1040,979,NaN]	5	hSpCas9	negative selection	9793991
42469557	42469580	12	-	27869803	PATU8988S	viability after 35 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.19721804671517085	[1064]	[605,376,NaN]	2	hSpCas9	negative selection	9793992
42472385	42472408	12	+	27869803	PATU8988S	viability after 35 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.16932892823810375	[924]	[456,204,NaN]	-2	hSpCas9	negative selection	9793993
42468644	42468667	12	-	27869803	PATU8988S	viability after 31 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.5686961371654204	[1787]	[862,1304,NaN]	6	hSpCas9	negative selection	9876440
42469557	42469580	12	-	27869803	PATU8988S	viability after 31 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.13836859706480953	[1064]	[506,416,NaN]	1	hSpCas9	negative selection	9876441
42472385	42472408	12	+	27869803	PATU8988S	viability after 31 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-0.0754630176111063	[924]	[353,344,NaN]	-1	hSpCas9	negative selection	9876442
42468644	42468667	12	-	27869803	HPAFII	viability after 35 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.8407559797706847	[788]	[871,538,NaN]	5	hSpCas9	negative selection	9958889
42469557	42469580	12	-	27869803	HPAFII	viability after 35 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	-0.013690249764157003	[432]	[250,178,NaN]	0	hSpCas9	negative selection	9958890
42472385	42472408	12	+	27869803	HPAFII	viability after 35 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-1.4288356101214124	[376]	[84,54,NaN]	-6	hSpCas9	negative selection	9958891
42468644	42468667	12	-	27869803	HPAFII	viability after 31 days	ATGCAGAACTGCTCAAACCACGG	PRICKLE1	ENSG00000139174	0.700354908727916	[788]	[875,548,NaN]	5	hSpCas9	negative selection	10041338
42469557	42469580	12	-	27869803	HPAFII	viability after 31 days	TTGCCAGTCTTTGAGTGAAGAGG	PRICKLE1	ENSG00000139174	0.44187609524047333	[432]	[387,266,NaN]	3	hSpCas9	negative selection	10041339
42472385	42472408	12	+	27869803	HPAFII	viability after 31 days	CTGCTCTGGTCTCAGGCCCGGGG	PRICKLE1	ENSG00000139174	-1.073997822414478	[376]	[133,63,NaN]	-6	hSpCas9	negative selection	10041340
42470288	42470311	12	-	28162770	P31FUJ	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	-0.05289311439944422	[127]	[144]	0	hSpCas9	negative selection	10216854
42468735	42468758	12	+	28162770	P31FUJ	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	0.6574096500475095	[115]	[214]	7	hSpCas9	negative selection	10216855
42469506	42469529	12	-	28162770	P31FUJ	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	-0.1968453266379691	[316]	[324]	-2	hSpCas9	negative selection	10216856
42468754	42468777	12	+	28162770	P31FUJ	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.17826639266151945	[363]	[483]	1	hSpCas9	negative selection	10216857
42466347	42466370	12	-	28162770	P31FUJ	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	0.24065198108978703	[120]	[167]	2	hSpCas9	negative selection	10216858
42466242	42466265	12	+	28162770	P31FUJ	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	1.0955236616711344	[44]	[112]	9	hSpCas9	negative selection	10216859
42472457	42472480	12	+	28162770	P31FUJ	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	0.45372696614087404	[488]	[786]	5	hSpCas9	negative selection	10216860
42470335	42470358	12	+	28162770	P31FUJ	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.682912241581146	[325]	[614]	7	hSpCas9	negative selection	10216861
42468764	42468787	12	+	28162770	P31FUJ	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	-0.21800520248629796	[96]	[97]	-2	hSpCas9	negative selection	10216862
42470288	42470311	12	-	28162770	TF1	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10386220
42468735	42468758	12	+	28162770	TF1	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10386221
42469506	42469529	12	-	28162770	TF1	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	NaN	[NaN]	[78]	1	hSpCas9	negative selection	10386222
42468754	42468777	12	+	28162770	TF1	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	NaN	[NaN]	[359]	1	hSpCas9	negative selection	10386223
42466347	42466370	12	-	28162770	TF1	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10386224
42466242	42466265	12	+	28162770	TF1	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10386225
42472457	42472480	12	+	28162770	TF1	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	NaN	[NaN]	[527]	1	hSpCas9	negative selection	10386226
42470335	42470358	12	+	28162770	TF1	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	NaN	[NaN]	[198]	1	hSpCas9	negative selection	10386227
42468764	42468787	12	+	28162770	TF1	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	NaN	[NaN]	[19]	1	hSpCas9	negative selection	10386228
42470288	42470311	12	-	28162770	SKM1	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	1.4796540018390956	[42]	[211]	9	hSpCas9	negative selection	10555586
42468735	42468758	12	+	28162770	SKM1	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	-0.7395395378300325	[16]	[17]	-5	hSpCas9	negative selection	10555587
42469506	42469529	12	-	28162770	SKM1	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	-0.523239587713686	[112]	[138]	-4	hSpCas9	negative selection	10555588
42468754	42468777	12	+	28162770	SKM1	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.016247231981382337	[98]	[176]	0	hSpCas9	negative selection	10555589
42466347	42466370	12	-	28162770	SKM1	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	-0.09851933321942152	[42]	[70]	-1	hSpCas9	negative selection	10555590
42466242	42466265	12	+	28162770	SKM1	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	0.017533629784748372	[18]	[33]	0	hSpCas9	negative selection	10555591
42472457	42472480	12	+	28162770	SKM1	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	0.4453200662148864	[139]	[336]	4	hSpCas9	negative selection	10555592
42470335	42470358	12	+	28162770	SKM1	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.3534403083878726	[57]	[130]	3	hSpCas9	negative selection	10555593
42468764	42468787	12	+	28162770	SKM1	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	0.6925714748077527	[13]	[39]	6	hSpCas9	negative selection	10555594
42470288	42470311	12	-	28162770	SKM1	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	1.4796540018390956	[42]	[211]	9	hSpCas9	negative selection	10724952
42468735	42468758	12	+	28162770	SKM1	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	-0.7395395378300325	[16]	[17]	-5	hSpCas9	negative selection	10724953
42469506	42469529	12	-	28162770	SKM1	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	-0.523239587713686	[112]	[138]	-4	hSpCas9	negative selection	10724954
42468754	42468777	12	+	28162770	SKM1	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.016247231981382337	[98]	[176]	0	hSpCas9	negative selection	10724955
42466347	42466370	12	-	28162770	SKM1	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	-0.09851933321942152	[42]	[70]	-1	hSpCas9	negative selection	10724956
42466242	42466265	12	+	28162770	SKM1	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	0.017533629784748372	[18]	[33]	0	hSpCas9	negative selection	10724957
42472457	42472480	12	+	28162770	SKM1	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	0.4453200662148864	[139]	[336]	4	hSpCas9	negative selection	10724958
42470335	42470358	12	+	28162770	SKM1	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.3534403083878726	[57]	[130]	3	hSpCas9	negative selection	10724959
42468764	42468787	12	+	28162770	SKM1	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	0.6925714748077527	[13]	[39]	6	hSpCas9	negative selection	10724960
42470288	42470311	12	-	28162770	PL21	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	-0.8393887496973174	[147]	[35]	-5	hSpCas9	negative selection	10894318
42468735	42468758	12	+	28162770	PL21	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	-0.6530189971814084	[111]	[30]	-4	hSpCas9	negative selection	10894319
42469506	42469529	12	-	28162770	PL21	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	-1.150357632594813	[305]	[59]	-6	hSpCas9	negative selection	10894320
42468754	42468777	12	+	28162770	PL21	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	-0.09942066736958777	[287]	[116]	0	hSpCas9	negative selection	10894321
42466347	42466370	12	-	28162770	PL21	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	1.0273030176271045	[185]	[164]	8	hSpCas9	negative selection	10894322
42466242	42466265	12	+	28162770	PL21	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	-4.632750399675422	[56]	[0]	-9	hSpCas9	negative selection	10894323
42472457	42472480	12	+	28162770	PL21	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	0.42457118109936665	[403]	[235]	4	hSpCas9	negative selection	10894324
42470335	42470358	12	+	28162770	PL21	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.5887049024069728	[219]	[143]	5	hSpCas9	negative selection	10894325
42468764	42468787	12	+	28162770	PL21	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	-1.531664274561107	[92]	[13]	-7	hSpCas9	negative selection	10894326
42470288	42470311	12	-	28162770	P31FUJ	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	-0.05289311439944422	[127]	[144]	0	hSpCas9	negative selection	11063684
42468735	42468758	12	+	28162770	P31FUJ	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	0.6574096500475095	[115]	[214]	7	hSpCas9	negative selection	11063685
42469506	42469529	12	-	28162770	P31FUJ	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	-0.1968453266379691	[316]	[324]	-2	hSpCas9	negative selection	11063686
42468754	42468777	12	+	28162770	P31FUJ	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.17826639266151945	[363]	[483]	1	hSpCas9	negative selection	11063687
42466347	42466370	12	-	28162770	P31FUJ	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	0.24065198108978703	[120]	[167]	2	hSpCas9	negative selection	11063688
42466242	42466265	12	+	28162770	P31FUJ	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	1.0955236616711344	[44]	[112]	9	hSpCas9	negative selection	11063689
42472457	42472480	12	+	28162770	P31FUJ	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	0.45372696614087404	[488]	[786]	5	hSpCas9	negative selection	11063690
42470335	42470358	12	+	28162770	P31FUJ	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.682912241581146	[325]	[614]	7	hSpCas9	negative selection	11063691
42468764	42468787	12	+	28162770	P31FUJ	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	-0.21800520248629796	[96]	[97]	-2	hSpCas9	negative selection	11063692
42470288	42470311	12	-	28162770	OCIAML5	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	-0.4984296162492963	[89]	[114]	-3	hSpCas9	negative selection	11233050
42468735	42468758	12	+	28162770	OCIAML5	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	0.8606514770555318	[71]	[235]	7	hSpCas9	negative selection	11233051
42469506	42469529	12	-	28162770	OCIAML5	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	0.42659407011919614	[175]	[426]	3	hSpCas9	negative selection	11233052
42468754	42468777	12	+	28162770	OCIAML5	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.6699646741307026	[163]	[470]	6	hSpCas9	negative selection	11233053
42466347	42466370	12	-	28162770	OCIAML5	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	1.3259863114617159	[58]	[266]	9	hSpCas9	negative selection	11233054
42466242	42466265	12	+	28162770	OCIAML5	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	-2.4139454584721123	[61]	[20]	-8	hSpCas9	negative selection	11233055
42472457	42472480	12	+	28162770	OCIAML5	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	0.3595381091173664	[325]	[754]	3	hSpCas9	negative selection	11233056
42470335	42470358	12	+	28162770	OCIAML5	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.3840007873695275	[224]	[529]	3	hSpCas9	negative selection	11233057
42468764	42468787	12	+	28162770	OCIAML5	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	0.5845731829000578	[57]	[156]	5	hSpCas9	negative selection	11233058
42470288	42470311	12	-	28162770	EOL1	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	-0.7758919465705576	[285]	[87]	-5	hSpCas9	negative selection	11402416
42468735	42468758	12	+	28162770	EOL1	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	-1.4957840273778222	[90]	[16]	-7	hSpCas9	negative selection	11402417
42469506	42469529	12	-	28162770	EOL1	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	0.5729834423069184	[540]	[423]	5	hSpCas9	negative selection	11402418
42468754	42468777	12	+	28162770	EOL1	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.462884112420335	[565]	[410]	4	hSpCas9	negative selection	11402419
42466347	42466370	12	-	28162770	EOL1	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	0.7238504213334056	[307]	[267]	6	hSpCas9	negative selection	11402420
42466242	42466265	12	+	28162770	EOL1	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	1.407870010415853	[97]	[136]	9	hSpCas9	negative selection	11402421
42472457	42472480	12	+	28162770	EOL1	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	0.20117124215228332	[633]	[383]	1	hSpCas9	negative selection	11402422
42470335	42470358	12	+	28162770	EOL1	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	1.1019840322902317	[297]	[336]	8	hSpCas9	negative selection	11402423
42468764	42468787	12	+	28162770	EOL1	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	-0.10402138062623645	[101]	[49]	-1	hSpCas9	negative selection	11402424
42470288	42470311	12	-	28162770	MOLM13	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	0.23376766762602363	[246]	[209]	1	hSpCas9	negative selection	11571782
42468735	42468758	12	+	28162770	MOLM13	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	-0.4593542760201071	[231]	[121]	-3	hSpCas9	negative selection	11571783
42469506	42469529	12	-	28162770	MOLM13	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	0.0936374971122354	[371]	[286]	0	hSpCas9	negative selection	11571784
42468754	42468777	12	+	28162770	MOLM13	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.9247911884536578	[466]	[640]	7	hSpCas9	negative selection	11571785
42466347	42466370	12	-	28162770	MOLM13	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	0.9327754302739842	[191]	[264]	7	hSpCas9	negative selection	11571786
42466242	42466265	12	+	28162770	MOLM13	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	-0.37384853453868905	[137]	[76]	-2	hSpCas9	negative selection	11571787
42472457	42472480	12	+	28162770	MOLM13	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	0.3379125944295276	[649]	[593]	2	hSpCas9	negative selection	11571788
42470335	42470358	12	+	28162770	MOLM13	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	-0.21608312500774296	[489]	[304]	-1	hSpCas9	negative selection	11571789
42468764	42468787	12	+	28162770	MOLM13	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	0.021373650792567034	[138]	[101]	0	hSpCas9	negative selection	11571790
42470288	42470311	12	-	28162770	HEL	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	-0.16144184226210345	[226]	[129]	-1	hSpCas9	negative selection	11741148
42468735	42468758	12	+	28162770	HEL	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	1.0164173015181432	[114]	[148]	8	hSpCas9	negative selection	11741149
42469506	42469529	12	-	28162770	HEL	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	0.18980472496298462	[359]	[262]	1	hSpCas9	negative selection	11741150
42468754	42468777	12	+	28162770	HEL	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.9507127553729567	[373]	[462]	8	hSpCas9	negative selection	11741151
42466347	42466370	12	-	28162770	HEL	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	0.4921791554249756	[221]	[199]	4	hSpCas9	negative selection	11741152
42466242	42466265	12	+	28162770	HEL	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	0.6766861639236945	[83]	[85]	6	hSpCas9	negative selection	11741153
42472457	42472480	12	+	28162770	HEL	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	-0.40131634807757843	[531]	[257]	-3	hSpCas9	negative selection	11741154
42470335	42470358	12	+	28162770	HEL	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.07847532394703705	[345]	[233]	0	hSpCas9	negative selection	11741155
42468764	42468787	12	+	28162770	HEL	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	-0.44472400924998223	[101]	[47]	-3	hSpCas9	negative selection	11741156
42470288	42470311	12	-	28162770	MV411	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	-0.12453122660418253	[175]	[135]	-1	hSpCas9	negative selection	11910514
42468735	42468758	12	+	28162770	MV411	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	-0.9224874506595371	[71]	[31]	-6	hSpCas9	negative selection	11910515
42469506	42469529	12	-	28162770	MV411	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	0.443199275089314	[288]	[330]	4	hSpCas9	negative selection	11910516
42468754	42468777	12	+	28162770	MV411	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.25738721119038044	[288]	[290]	2	hSpCas9	negative selection	11910517
42466347	42466370	12	-	28162770	MV411	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	1.0274718668408676	[98]	[169]	8	hSpCas9	negative selection	11910518
42466242	42466265	12	+	28162770	MV411	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	1.4089009734768916	[37]	[84]	9	hSpCas9	negative selection	11910519
42472457	42472480	12	+	28162770	MV411	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	0.3697416477127138	[372]	[405]	3	hSpCas9	negative selection	11910520
42470335	42470358	12	+	28162770	MV411	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.3771286274224121	[201]	[220]	3	hSpCas9	negative selection	11910521
42468764	42468787	12	+	28162770	MV411	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	-0.0004899626608101393	[94]	[79]	0	hSpCas9	negative selection	11910522
42470288	42470311	12	-	28162770	MONOMAC1	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	0.07305231630819073	[101]	[122]	0	hSpCas9	negative selection	12079880
42468735	42468758	12	+	28162770	MONOMAC1	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	0.5641762933533296	[58]	[99]	5	hSpCas9	negative selection	12079881
42469506	42469529	12	-	28162770	MONOMAC1	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	1.2347477270564429	[181]	[490]	9	hSpCas9	negative selection	12079882
42468754	42468777	12	+	28162770	MONOMAC1	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.4096207247609215	[219]	[334]	4	hSpCas9	negative selection	12079883
42466347	42466370	12	-	28162770	MONOMAC1	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	0.7824018304581298	[105]	[208]	7	hSpCas9	negative selection	12079884
42466242	42466265	12	+	28162770	MONOMAC1	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	1.4775628661462787	[25]	[82]	9	hSpCas9	negative selection	12079885
42472457	42472480	12	+	28162770	MONOMAC1	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	-0.42349663799419346	[295]	[252]	-4	hSpCas9	negative selection	12079886
42470335	42470358	12	+	28162770	MONOMAC1	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.5836501245359704	[116]	[200]	5	hSpCas9	negative selection	12079887
42468764	42468787	12	+	28162770	MONOMAC1	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	-1.2245175834816608	[52]	[25]	-7	hSpCas9	negative selection	12079888
42470288	42470311	12	-	28162770	OCIAML2	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	0.151421994214215	[31]	[196]	1	hSpCas9	negative selection	12249246
42468735	42468758	12	+	28162770	OCIAML2	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	0.8331509229349416	[7]	[78]	7	hSpCas9	negative selection	12249247
42469506	42469529	12	-	28162770	OCIAML2	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	-0.3652768250959326	[65]	[283]	-3	hSpCas9	negative selection	12249248
42468754	42468777	12	+	28162770	OCIAML2	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.6248169602408749	[52]	[452]	6	hSpCas9	negative selection	12249249
42466347	42466370	12	-	28162770	OCIAML2	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	0.30195967865476636	[17]	[122]	3	hSpCas9	negative selection	12249250
42466242	42466265	12	+	28162770	OCIAML2	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	1.875145011599569	[8]	[182]	9	hSpCas9	negative selection	12249251
42472457	42472480	12	+	28162770	OCIAML2	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	0.4735169400243213	[78]	[607]	4	hSpCas9	negative selection	12249252
42470335	42470358	12	+	28162770	OCIAML2	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	0.38735116988541085	[31]	[231]	4	hSpCas9	negative selection	12249253
42468764	42468787	12	+	28162770	OCIAML2	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	0.11433267547899484	[13]	[83]	1	hSpCas9	negative selection	12249254
42470288	42470311	12	-	28162770	OCIAML3	viability	ACAGCCCCGGAGAGAAGCATCGG	PRICKLE1	ENSG00000139174	0.1407019799016752	[63]	[212]	1	hSpCas9	negative selection	12418612
42468735	42468758	12	+	28162770	OCIAML3	viability	GTGAAACAGACAAAACAGGATGG	PRICKLE1	ENSG00000139174	1.2209604658433162	[26]	[189]	8	hSpCas9	negative selection	12418613
42469506	42469529	12	-	28162770	OCIAML3	viability	TCAGCGGAAGAAAGAAGCACTGG	PRICKLE1	ENSG00000139174	-0.11527546572792968	[107]	[300]	-1	hSpCas9	negative selection	12418614
42468754	42468777	12	+	28162770	OCIAML3	viability	ATGGGTGCCAGCACACACCAGGG	PRICKLE1	ENSG00000139174	0.34764837344503186	[81]	[314]	3	hSpCas9	negative selection	12418615
42466347	42466370	12	-	28162770	OCIAML3	viability	TGATGAGTGCACAGAAGCTGAGG	PRICKLE1	ENSG00000139174	-0.08499399283630549	[38]	[110]	0	hSpCas9	negative selection	12418616
42466242	42466265	12	+	28162770	OCIAML3	viability	AACAGCCACAGCAGAAGGGGCGG	PRICKLE1	ENSG00000139174	1.2133472817334412	[11]	[83]	8	hSpCas9	negative selection	12418617
42472457	42472480	12	+	28162770	OCIAML3	viability	GGAACTTCTCTGACAGCCAAAGG	PRICKLE1	ENSG00000139174	-0.16550788123875693	[119]	[322]	-1	hSpCas9	negative selection	12418618
42470335	42470358	12	+	28162770	OCIAML3	viability	GTAAGCAAGCAAAATAGAGCTGG	PRICKLE1	ENSG00000139174	-0.16824373445226082	[66]	[179]	-1	hSpCas9	negative selection	12418619
42468764	42468787	12	+	28162770	OCIAML3	viability	GCACACACCAGGGCCCGCACGGG	PRICKLE1	ENSG00000139174	0.39350141549264	[28]	[114]	3	hSpCas9	negative selection	12418620