Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 166336
• Symbol: PRICKLE2
• Description: prickle planar cell polarity protein 2

DataSource: http://genomecrispr.dkfz.de/#!/results/PRICKLE2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
64157290	64157313	3	+	26472758	Jiyoye	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	0.577100382948186	[39]	[44]	4	hSpCas9	negative selection	127203
64147157	64147180	3	+	26472758	Jiyoye	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	0.44324463621339516	[78]	[80]	3	hSpCas9	negative selection	127204
64147062	64147085	3	-	26472758	Jiyoye	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	-0.2879700369657058	[271]	[167]	-2	hSpCas9	negative selection	127205
64159972	64159995	3	+	26472758	Jiyoye	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.4071753815058734	[220]	[220]	3	hSpCas9	negative selection	127206
64157313	64157336	3	-	26472758	Jiyoye	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	0.3729596661679604	[127]	[124]	3	hSpCas9	negative selection	127207
64157271	64157294	3	+	26472758	Jiyoye	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	-3.815217039830575	[55]	[2]	-9	hSpCas9	negative selection	127208
64157211	64157234	3	-	26472758	Jiyoye	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	5.992137882227029	[0]	[47]	9	hSpCas9	negative selection	127209
64153215	64153238	3	+	26472758	Jiyoye	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.3457748368417301	[167]	[160]	2	hSpCas9	negative selection	127210
64147595	64147618	3	+	26472758	Jiyoye	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	0.40717538150587346	[67]	[67]	3	hSpCas9	negative selection	127211
64147305	64147328	3	-	26472758	Jiyoye	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	0.06234688450843229	[253]	[199]	0	hSpCas9	negative selection	127212
64157290	64157313	3	+	26472758	KBM7	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	0.6944712985848267	[199,92]	[138,79]	7	hSpCas9	negative selection	318321
64147157	64147180	3	+	26472758	KBM7	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	0.628930353073778	[547,420]	[362,336]	7	hSpCas9	negative selection	318322
64147062	64147085	3	-	26472758	KBM7	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	0.2594684719109905	[686,299]	[277,258]	2	hSpCas9	negative selection	318323
64159972	64159995	3	+	26472758	KBM7	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.18930964712421744	[782,483]	[255,401]	2	hSpCas9	negative selection	318324
64157313	64157336	3	-	26472758	KBM7	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	1.1655513156997928	[669,614]	[564,778]	9	hSpCas9	negative selection	318325
64157271	64157294	3	+	26472758	KBM7	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	0.8063501118797616	[111,69]	[55,88]	8	hSpCas9	negative selection	318326
64157211	64157234	3	-	26472758	KBM7	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	0.0875527886591192	[109,181]	[81,68]	0	hSpCas9	negative selection	318327
64153215	64153238	3	+	26472758	KBM7	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.34864888698971774	[796,878]	[474,534]	3	hSpCas9	negative selection	318328
64147595	64147618	3	+	26472758	KBM7	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	0.8338370192345413	[203,146]	[166,125]	8	hSpCas9	negative selection	318329
64147305	64147328	3	-	26472758	KBM7	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	-0.22840940435059032	[793,734]	[323,291]	-2	hSpCas9	negative selection	318330
64157290	64157313	3	+	26472758	Raji	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	1.9698800116236648	[54]	[49]	9	hSpCas9	negative selection	509439
64147157	64147180	3	+	26472758	Raji	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	0.9946834026242373	[172]	[79]	8	hSpCas9	negative selection	509440
64147062	64147085	3	-	26472758	Raji	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	-0.0915499131388594	[426]	[92]	-1	hSpCas9	negative selection	509441
64159972	64159995	3	+	26472758	Raji	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	-0.09773089453101286	[331]	[71]	-1	hSpCas9	negative selection	509442
64157313	64157336	3	-	26472758	Raji	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	0.700208153867726	[243]	[91]	6	hSpCas9	negative selection	509443
64157271	64157294	3	+	26472758	Raji	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	2.2329144174574584	[10]	[11]	9	hSpCas9	negative selection	509444
64157211	64157234	3	-	26472758	Raji	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	0.8443491295398053	[35]	[14]	7	hSpCas9	negative selection	509445
64153215	64153238	3	+	26472758	Raji	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.6653130773977397	[412]	[151]	6	hSpCas9	negative selection	509446
64147595	64147618	3	+	26472758	Raji	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	0.06785517118696205	[147]	[35]	0	hSpCas9	negative selection	509447
64147305	64147328	3	-	26472758	Raji	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	0.7388444981946476	[345]	[133]	7	hSpCas9	negative selection	509448
64157290	64157313	3	+	26472758	K562	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	0.39483557021954496	[90]	[100]	3	hSpCas9	negative selection	700557
64147157	64147180	3	+	26472758	K562	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	1.0744937262241345	[251]	[447]	8	hSpCas9	negative selection	700558
64147062	64147085	3	-	26472758	K562	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	0.4473438479713755	[436]	[502]	3	hSpCas9	negative selection	700559
64159972	64159995	3	+	26472758	K562	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.17116974563580822	[504]	[479]	1	hSpCas9	negative selection	700560
64157313	64157336	3	-	26472758	K562	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	1.4339568386072945	[551]	[1258]	9	hSpCas9	negative selection	700561
64157271	64157294	3	+	26472758	K562	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	0.696292995125662	[86]	[118]	6	hSpCas9	negative selection	700562
64157211	64157234	3	-	26472758	K562	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	-2.2207040030487057	[126]	[22]	-7	hSpCas9	negative selection	700563
64153215	64153238	3	+	26472758	K562	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.53375889605353	[787]	[962]	4	hSpCas9	negative selection	700564
64147595	64147618	3	+	26472758	K562	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	-0.8972424215571444	[138]	[62]	-5	hSpCas9	negative selection	700565
64147305	64147328	3	-	26472758	K562	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	0.44909636110373985	[596]	[687]	3	hSpCas9	negative selection	700566
64153253	64153276	3	-	26627737	DLD1	viability	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	0.1934365563963853	[446]	[194,147,138]	2	hSpCas9	negative selection	822929
64157272	64157295	3	+	26627737	DLD1	viability	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	0.5109013226951598	[103]	[75,69,0]	5	hSpCas9	negative selection	822930
64159972	64159995	3	+	26627737	DLD1	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	-3.322341469071882	[31]	[0,0,0]	-9	hSpCas9	negative selection	822931
64153253	64153276	3	-	26627737	GBM cells	viability after 5 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	-0.08760289575069236	[425]	[158,270]	-1	hSpCas9	negative selection	905244
64157272	64157295	3	+	26627737	GBM cells	viability after 5 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	-0.011818787017227272	[46]	[24,24]	0	hSpCas9	negative selection	905245
64159972	64159995	3	+	26627737	GBM cells	viability after 5 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.5993535930267777	[15]	[19,5]	8	hSpCas9	negative selection	905246
64153253	64153276	3	-	26627737	GBM cells	viability after 13 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	0.14340998943411132	[425]	[294,222]	1	hSpCas9	negative selection	987559
64157272	64157295	3	+	26627737	GBM cells	viability after 13 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	-0.5969279297687362	[46]	[12,19]	-6	hSpCas9	negative selection	987560
64159972	64159995	3	+	26627737	GBM cells	viability after 13 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	1.8037690718673645	[15]	[26,32]	9	hSpCas9	negative selection	987561
64153253	64153276	3	-	26627737	GBM cells	viability after 21 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	0.29961041261829535	[425]	[299,270]	3	hSpCas9	negative selection	1069874
64157272	64157295	3	+	26627737	GBM cells	viability after 21 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	-0.9937811397461713	[46]	[16,8]	-7	hSpCas9	negative selection	1069875
64159972	64159995	3	+	26627737	GBM cells	viability after 21 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	-0.4046054765364837	[15]	[4,7]	-4	hSpCas9	negative selection	1069876
64153253	64153276	3	-	26627737	RPE1	viability after 9 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	0.9076351981866044	[1045]	[495,766]	6	hSpCas9	negative selection	1152189
64157272	64157295	3	+	26627737	RPE1	viability after 9 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	1.8707894585195142	[94]	[120,92]	8	hSpCas9	negative selection	1152190
64159972	64159995	3	+	26627737	RPE1	viability after 9 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	1.799798980606885	[22]	[28,19]	8	hSpCas9	negative selection	1152191
64153253	64153276	3	-	26627737	RPE1	viability after 12 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	0.839039152118257	[1045]	[441,566]	5	hSpCas9	negative selection	1234504
64157272	64157295	3	+	26627737	RPE1	viability after 12 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	1.7264033405433747	[94]	[65,103]	8	hSpCas9	negative selection	1234505
64159972	64159995	3	+	26627737	RPE1	viability after 12 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	1.998153940834627	[22]	[30,17]	8	hSpCas9	negative selection	1234506
64153253	64153276	3	-	26627737	RPE1	viability after 15 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	1.3393544547746297	[1045]	[820,678]	7	hSpCas9	negative selection	1316819
64157272	64157295	3	+	26627737	RPE1	viability after 15 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	2.0790455413087865	[94]	[138,88]	8	hSpCas9	negative selection	1316820
64159972	64159995	3	+	26627737	RPE1	viability after 15 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	-2.7018130821851187	[22]	[0,0]	-9	hSpCas9	negative selection	1316821
64153253	64153276	3	-	26627737	RPE1	viability after 18 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	1.134849800472327	[1045]	[630,607]	6	hSpCas9	negative selection	1399134
64157272	64157295	3	+	26627737	RPE1	viability after 18 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	2.1512024525837776	[94]	[124,101]	9	hSpCas9	negative selection	1399135
64159972	64159995	3	+	26627737	RPE1	viability after 18 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	1.267974060127055	[22]	[27,0]	7	hSpCas9	negative selection	1399136
64153253	64153276	3	-	26627737	HeLa	viability after 8 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	-0.38301251826578664	[735]	[232,225,272]	-4	hSpCas9	negative selection	1481449
64157272	64157295	3	+	26627737	HeLa	viability after 8 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	5.999528241559502	[0]	[90,1,5]	9	hSpCas9	negative selection	1481450
64159972	64159995	3	+	26627737	HeLa	viability after 8 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.18185256845690567	[50]	[24,32,17]	1	hSpCas9	negative selection	1481451
64153253	64153276	3	-	26627737	HeLa	viability after 12 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	-0.4529627907074232	[735]	[296,172,203]	-4	hSpCas9	negative selection	1563764
64157272	64157295	3	+	26627737	HeLa	viability after 12 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	6.143944506655792	[0]	[20,4,63]	9	hSpCas9	negative selection	1563765
64159972	64159995	3	+	26627737	HeLa	viability after 12 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	1.1085089562031591	[50]	[0,26,108]	7	hSpCas9	negative selection	1563766
64153253	64153276	3	-	26627737	HeLa	viability after 15 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	-0.3808912099443824	[735]	[113,284,297]	-3	hSpCas9	negative selection	1646079
64157272	64157295	3	+	26627737	HeLa	viability after 15 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	5.615699031657202	[0]	[3,0,57]	9	hSpCas9	negative selection	1646080
64159972	64159995	3	+	26627737	HeLa	viability after 15 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.5601371290840271	[50]	[37,19,33]	4	hSpCas9	negative selection	1646081
64153253	64153276	3	-	26627737	HeLa	viability after 18 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	-0.3676724642524274	[735]	[78,237,297]	-3	hSpCas9	negative selection	1728394
64157272	64157295	3	+	26627737	HeLa	viability after 18 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	5.595257200128954	[0]	[1,0,57]	9	hSpCas9	negative selection	1728395
64159972	64159995	3	+	26627737	HeLa	viability after 18 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.5949615961855188	[50]	[24,18,33]	5	hSpCas9	negative selection	1728396
64153253	64153276	3	-	26627737	HCT116	viability after 6 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	-0.3078401523296853	[994]	[68,157]	-2	hSpCas9	negative selection	1810709
64157272	64157295	3	+	26627737	HCT116	viability after 6 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	-0.3254940860195292	[241]	[1,45]	-2	hSpCas9	negative selection	1810710
64159972	64159995	3	+	26627737	HCT116	viability after 6 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	-1.1849563080752845	[116]	[0,11]	-6	hSpCas9	negative selection	1810711
64153253	64153276	3	-	26627737	HCT116	viability after 8 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	0.23159836710619552	[409]	[215,238,338]	2	hSpCas9	negative selection	1893024
64157272	64157295	3	+	26627737	HCT116	viability after 8 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	-3.1904434299585507	[132]	[3,10,8]	-9	hSpCas9	negative selection	1893025
64159972	64159995	3	+	26627737	HCT116	viability after 8 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	5.0277308501546685	[0]	[15,28,8]	9	hSpCas9	negative selection	1893026
64153253	64153276	3	-	26627737	HCT116	viability after 9 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	0.35406850770490916	[994]	[333,343]	2	hSpCas9	negative selection	1975339
64157272	64157295	3	+	26627737	HCT116	viability after 9 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	0.27751508800685354	[241]	[17,125]	2	hSpCas9	negative selection	1975340
64159972	64159995	3	+	26627737	HCT116	viability after 9 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	-1.4022387699619583	[116]	[3,17]	-7	hSpCas9	negative selection	1975341
64153253	64153276	3	-	26627737	HCT116	viability after 12 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	0.18217155713841127	[409]	[278,146,301]	2	hSpCas9	negative selection	2057654
64157272	64157295	3	+	26627737	HCT116	viability after 12 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	-0.9419970248180827	[132]	[8,54,47]	-7	hSpCas9	negative selection	2057655
64159972	64159995	3	+	26627737	HCT116	viability after 12 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	5.611006571859262	[0]	[2,64,11]	9	hSpCas9	negative selection	2057656
64153253	64153276	3	-	26627737	HCT116	viability after 15 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	0.34730638241551337	[409]	[449,253,213]	3	hSpCas9	negative selection	2139969
64157272	64157295	3	+	26627737	HCT116	viability after 15 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	-1.1720959332640704	[132]	[4,44,47]	-8	hSpCas9	negative selection	2139970
64159972	64159995	3	+	26627737	HCT116	viability after 15 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	5.7416405759860085	[0]	[13,32,42]	9	hSpCas9	negative selection	2139971
64153253	64153276	3	-	26627737	HCT116	viability after 18 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	0.05557556923233886	[409]	[244,189,182]	0	hSpCas9	negative selection	2222284
64157272	64157295	3	+	26627737	HCT116	viability after 18 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	-2.360224340166445	[132]	[0,4,32]	-9	hSpCas9	negative selection	2222285
64159972	64159995	3	+	26627737	HCT116	viability after 18 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	3.6734417205791594	[0]	[5,1,10]	9	hSpCas9	negative selection	2222286
64277276	64277299	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGTAATCCCAGCACTTCGGGTGG	PRICKLE2	ENSG00000163637	-3.9690945324429574	[10,229]	[0,1]	-9	dCas9-VP64	positive selection	2383171
64424703	64424726	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGAGGACTGCTTGAGCCCAGG	PRICKLE2	ENSG00000163637	0.7107825170273987	[226,48]	[71,23]	3	dCas9-VP64	positive selection	2383428
64424674	64424697	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTAATCCCAGCACTTTGAGAAG	PRICKLE2	ENSG00000163637	-0.7112509309644206	[46,33]	[6,2]	-4	dCas9-VP64	positive selection	2394179
64204560	64204583	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGTTGTTGTTGTTGTTGTTCAG	PRICKLE2	ENSG00000163637	-1.2553913082042603	[104,179]	[19,4]	-7	dCas9-VP64	positive selection	2401264
64308083	64308106	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGTGAGCCACCATGCCGGG	PRICKLE2	ENSG00000163637	-2.540049325425791	[4,100]	[0,1]	-9	dCas9-VP64	positive selection	2419192
64213118	64213141	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCATTGCACTCCAGCTTGG	PRICKLE2	ENSG00000163637	0.14794526525316742	[282,182]	[37,75]	0	dCas9-VP64	positive selection	2421146
64336058	64336081	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAACTCCGCCTCCTGG	PRICKLE2	ENSG00000163637	-1.1801124495404707	[373,350]	[49,18]	-6	dCas9-VP64	positive selection	2448414
64145137	64145160	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCCCAGGCTGGAGTGCAGAGG	PRICKLE2	ENSG00000163637	1.5196799666234522	[9,52]	[2,38]	5	dCas9-VP64	positive selection	2457363
64225598	64225621	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTTCCCCTCTCCCTGGCTTGGGG	PRICKLE2	ENSG00000163637	-0.9529520382207461	[157,210]	[22,17]	-5	dCas9-VP64	positive selection	2475079
64225576	64225599	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	GATTATTGATTTGGAAGGCAAGG	PRICKLE2	ENSG00000163637	0.6233710825396567	[90,77]	[43,11]	2	dCas9-VP64	positive selection	2475080
64225625	64225648	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGCCTTTGCATCCAGCAAAGG	PRICKLE2	ENSG00000163637	1.038204426836251	[8,125]	[19,42]	4	dCas9-VP64	positive selection	2475081
64277276	64277299	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGTAATCCCAGCACTTCGGGTGG	PRICKLE2	ENSG00000163637	-1.0802329755633977	[58,72]	[5,12]	-9	dCas9-VP64	positive selection	2478426
64424703	64424726	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGAGGACTGCTTGAGCCCAGG	PRICKLE2	ENSG00000163637	0.4123872135065094	[127,354]	[119,88]	3	dCas9-VP64	positive selection	2478683
64424674	64424697	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTAATCCCAGCACTTTGAGAAG	PRICKLE2	ENSG00000163637	-0.5384167306991928	[64,169]	[16,33]	-5	dCas9-VP64	positive selection	2489434
64204560	64204583	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGTTGTTGTTGTTGTTGTTCAG	PRICKLE2	ENSG00000163637	-0.6691815338040683	[248,92]	[41,27]	-6	dCas9-VP64	positive selection	2496519
64308083	64308106	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGTGAGCCACCATGCCGGG	PRICKLE2	ENSG00000163637	0.03661325214909955	[138,24]	[31,22]	0	dCas9-VP64	positive selection	2514447
64213118	64213141	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCATTGCACTCCAGCTTGG	PRICKLE2	ENSG00000163637	-0.3408601233544918	[134,323]	[46,68]	-3	dCas9-VP64	positive selection	2516401
64336058	64336081	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAACTCCGCCTCCTGG	PRICKLE2	ENSG00000163637	1.4145647280039761	[84,145]	[146,55]	7	dCas9-VP64	positive selection	2543669
64145137	64145160	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCCCAGGCTGGAGTGCAGAGG	PRICKLE2	ENSG00000163637	-0.8181473823206423	[116,171]	[31,20]	-7	dCas9-VP64	positive selection	2552618
64225598	64225621	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTTCCCCTCTCCCTGGCTTGGGG	PRICKLE2	ENSG00000163637	-0.5851095012614811	[283,356]	[51,84]	-6	dCas9-VP64	positive selection	2570334
64225576	64225599	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	GATTATTGATTTGGAAGGCAAGG	PRICKLE2	ENSG00000163637	-0.02190025999076453	[99,116]	[34,33]	0	dCas9-VP64	positive selection	2570335
64225625	64225648	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGCCTTTGCATCCAGCAAAGG	PRICKLE2	ENSG00000163637	-0.4944158025628378	[16,42]	[6,5]	-5	dCas9-VP64	positive selection	2570336
64157272	64157295	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	-0.2819246912946469	[2,2]	[2,0]	-4	hSpCas9	positive selection	3013586
64160040	64160063	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCTTCTCTTCCTCATCCAGGG	PRICKLE2	ENSG00000163637	-0.04787437615465674	[3,4]	[4,2]	0	hSpCas9	positive selection	3013587
64159973	64159996	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	-0.3800167373922448	[2,2]	[2,0]	-5	hSpCas9	positive selection	3013588
64160056	64160079	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.22057949763706863	[3,3]	[2,1]	-3	hSpCas9	positive selection	3013589
64157272	64157295	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	0.2607458257983188	[2,2]	[3,0]	4	hSpCas9	positive selection	3081444
64160040	64160063	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCTTCTCTTCCTCATCCAGGG	PRICKLE2	ENSG00000163637	0.30979084367847876	[3,3]	[3,3]	5	hSpCas9	positive selection	3081445
64159973	64159996	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.1510852736332899	[2,2]	[3,1]	2	hSpCas9	positive selection	3081446
64160056	64160079	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.03890265855117844	[3,3]	[4,0]	0	hSpCas9	positive selection	3081447
64159989	64160012		-	24336571	A375	resistance to PLX after 7 days	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.23811947933611977	[11,9]	[8,8]	-7	hSpCas9	positive selection	3137710
64159989	64160012		-	24336571	A375	resistance to PLX after 14 days	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.2791955512212847	[8,8]	[2,2]	-3	hSpCas9	positive selection	3195503
64159989	64160012		-	24336571	A375	viability after 7 days	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.4358401503048923	[7]	[11,9]	6	hSpCas9	negative selection	3253296
64159989	64160012		-	24336571	A375	viability after 14 days	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.23061031283034317	[7]	[8,8]	3	hSpCas9	negative selection	3311089
64153254	64153277	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.6253168379160062	[235,235]	[0,0]	-4	hSpCas9	positive selection	3387424
64163071	64163094	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	-1.2264895658184216	[357,357]	[0,0]	-7	hSpCas9	positive selection	3387425
64157271	64157294	3	+	26780180	HT29	viability (Avana library 4 designs)	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	0.610606123141277	[]	[]	2	hSpCas9	negative selection	3451771
64160039	64160062	3	+	26780180	HT29	viability (Avana library 4 designs)	CCTCTTCTCTTCCTCATCCAGGG	PRICKLE2	ENSG00000163637	-0.444359744813411	[]	[]	-6	hSpCas9	negative selection	3451772
64159972	64159995	3	+	26780180	HT29	viability (Avana library 4 designs)	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.191152494664928	[]	[]	0	hSpCas9	negative selection	3451773
64160056	64160079	3	-	26780180	HT29	viability (Avana library 4 designs)	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.95950824017997	[]	[]	4	hSpCas9	negative selection	3451774
64159972	64159995	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	5.24900634822893	[]	[]	8	hSpCas9	negative selection	3547825
64157271	64157294	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	1.16973587376621	[]	[]	1	hSpCas9	negative selection	3547826
64160056	64160079	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-10.7260430310349	[]	[]	-8	hSpCas9	negative selection	3547827
64160039	64160062	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCTTCTCTTCCTCATCCAGGG	PRICKLE2	ENSG00000163637	-0.386125416289387	[]	[]	0	hSpCas9	negative selection	3547828
64157290	64157313	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	-13.6351538192756	[]	[]	-8	hSpCas9	negative selection	3547829
64147268	64147291	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACCATTATGGGAACAAGATGG	PRICKLE2	ENSG00000163637	-5.72376944858837	[]	[]	-6	hSpCas9	negative selection	3547830
64159972	64159995	3	+	26780180	A375	viability (Avana lentiGuide)	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	1.08061786505474	[]	[]	1	hSpCas9	negative selection	3656484
64157271	64157294	3	+	26780180	A375	viability (Avana lentiGuide)	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	6.92805685602949	[]	[]	5	hSpCas9	negative selection	3656485
64160056	64160079	3	-	26780180	A375	viability (Avana lentiGuide)	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-4.67770724105659	[]	[]	-7	hSpCas9	negative selection	3656486
64160039	64160062	3	+	26780180	A375	viability (Avana lentiGuide)	CCTCTTCTCTTCCTCATCCAGGG	PRICKLE2	ENSG00000163637	1.43019252241524	[]	[]	1	hSpCas9	negative selection	3656487
64157290	64157313	3	+	26780180	A375	viability (Avana lentiGuide)	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	-6.65469605376737	[]	[]	-9	hSpCas9	negative selection	3656488
64147268	64147291	3	-	26780180	A375	viability (Avana lentiGuide)	CTACCATTATGGGAACAAGATGG	PRICKLE2	ENSG00000163637	-6.59080176681837	[]	[]	-9	hSpCas9	negative selection	3656489
64159972	64159995	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.2176488955249474	[4]	[5,4]	6	hSpCas9	positive selection	3765091
64157271	64157294	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	-0.45300979476561876	[4]	[4,1]	-6	hSpCas9	positive selection	3765092
64160056	64160079	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.47455821921512226	[3]	[3,1]	-6	hSpCas9	positive selection	3765093
64160039	64160062	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCTTCTCTTCCTCATCCAGGG	PRICKLE2	ENSG00000163637	-0.1453180241391701	[5]	[5,3]	-2	hSpCas9	positive selection	3765094
64157290	64157313	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	-1.8119520922927985	[3]	[0,0]	-9	hSpCas9	positive selection	3765095
64147268	64147291	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACCATTATGGGAACAAGATGG	PRICKLE2	ENSG00000163637	-0.7294350133679532	[5]	[3,2]	-8	hSpCas9	positive selection	3765096
64159972	64159995	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	-0.034538163621241624	[5]	[4,4]	0	hSpCas9	positive selection	3873698
64157271	64157294	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	-1.0167698423659892	[5]	[2,0]	-8	hSpCas9	positive selection	3873699
64160056	64160079	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.08268232264379362	[5]	[4,4]	1	hSpCas9	positive selection	3873700
64160039	64160062	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCTTCTCTTCCTCATCCAGGG	PRICKLE2	ENSG00000163637	0.1536787093915863	[5]	[4,6]	3	hSpCas9	positive selection	3873701
64157290	64157313	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	0.03591418133042035	[3]	[1,4]	0	hSpCas9	positive selection	3873702
64147268	64147291	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACCATTATGGGAACAAGATGG	PRICKLE2	ENSG00000163637	0.31727387803523427	[5]	[6,5]	8	hSpCas9	positive selection	3873703
64159989	64160012	3	-	26780180	A375	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.904125474376939	[]	[]	4	hSpCas9	negative selection	3984142
64153254	64153277	3	+	26780180	A375	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	1.74090392150165	[]	[]	9	hSpCas9	negative selection	3984143
64153257	64153280	3	-	26780180	A375	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	1.08611639213058	[]	[]	5	hSpCas9	negative selection	3984144
64160056	64160079	3	-	26780180	A375	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	1.16386921219023	[]	[]	6	hSpCas9	negative selection	3984145
64163071	64163094	3	-	26780180	A375	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	1.79529387625421	[]	[]	9	hSpCas9	negative selection	3984146
64159989	64160012	3	-	26780180	HT29	viability (GeCKOv2 library)	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	1.41178095104755	[]	[]	7	hSpCas9	negative selection	4092108
64153254	64153277	3	+	26780180	HT29	viability (GeCKOv2 library)	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	1.13430310743089	[]	[]	5	hSpCas9	negative selection	4092109
64153257	64153280	3	-	26780180	HT29	viability (GeCKOv2 library)	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.873753839752115	[]	[]	3	hSpCas9	negative selection	4092110
64160056	64160079	3	-	26780180	HT29	viability (GeCKOv2 library)	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	1.50082147855046	[]	[]	7	hSpCas9	negative selection	4092111
64163071	64163094	3	-	26780180	HT29	viability (GeCKOv2 library)	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.591439433759802	[]	[]	2	hSpCas9	negative selection	4092112
64159989	64160012	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.45259942840449935	[3]	[1,1]	-8	hSpCas9	positive selection	4162859
64159989	64160012	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.2997812298037387	[3]	[0,0,1,0]	-4	hSpCas9	positive selection	4226881
64159989	64160012	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.11791464235480875	[2]	[2,1]	2	hSpCas9	positive selection	4292108
64153257	64153280	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.2474195629230448	[2]	[2,1]	5	hSpCas9	positive selection	4292109
64160056	64160079	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.3845896655720376	[3]	[3,0]	-7	hSpCas9	positive selection	4292110
64153254	64153277	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.1694518539080948	[3]	[3,2]	3	hSpCas9	positive selection	4356367
64163071	64163094	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.06556139885247642	[3]	[3,2]	1	hSpCas9	positive selection	4356368
64147380	64147402	3	+	27760321	OCIAML3	viability	GTCTACGTCGGCTGACAGCCGG	PRICKLE2	ENSG00000163637	0.9241926214282281	[524,459]	[655,824]	9	hSpCas9	negative selection	4430502
64147468	64147490	3	-	27760321	OCIAML3	viability	CCCGGCGCAGTGCCAAAATTGG	PRICKLE2	ENSG00000163637	0.7918103610927009	[315,241]	[304,465]	8	hSpCas9	negative selection	4430503
64157313	64157335	3	-	27760321	OCIAML3	viability	CTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	-0.7634346559307061	[772,706]	[299,393]	-6	hSpCas9	negative selection	4430504
64159988	64160010	3	-	27760321	OCIAML3	viability	ACGCGAAAACTTGGGCCGCGGG	PRICKLE2	ENSG00000163637	0.1970319356560961	[886,715]	[596,867]	2	hSpCas9	negative selection	4430505
64160056	64160078	3	-	27760321	OCIAML3	viability	GTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.7730475192205426	[669,575]	[249,328]	-6	hSpCas9	negative selection	4430506
64147380	64147402	3	+	27760321	OCIAML2	viability	GTCTACGTCGGCTGACAGCCGG	PRICKLE2	ENSG00000163637	0.3157801999306698	[524,459]	[496,491]	4	hSpCas9	negative selection	4513965
64147468	64147490	3	-	27760321	OCIAML2	viability	CCCGGCGCAGTGCCAAAATTGG	PRICKLE2	ENSG00000163637	0.6239064660806658	[315,241]	[257,459]	8	hSpCas9	negative selection	4513966
64157313	64157335	3	-	27760321	OCIAML2	viability	CTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	-0.297783265387828	[772,706]	[431,558]	-4	hSpCas9	negative selection	4513967
64159988	64160010	3	-	27760321	OCIAML2	viability	ACGCGAAAACTTGGGCCGCGGG	PRICKLE2	ENSG00000163637	0.5249293942936315	[886,715]	[806,1086]	7	hSpCas9	negative selection	4513968
64160056	64160078	3	-	27760321	OCIAML2	viability	GTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.10004368107669226	[669,575]	[450,653]	1	hSpCas9	negative selection	4513969
64147380	64147402	3	+	27760321	MV411	viability	GTCTACGTCGGCTGACAGCCGG	PRICKLE2	ENSG00000163637	0.35796444142001244	[524,459]	[220,707]	2	hSpCas9	negative selection	4597428
64147468	64147490	3	-	27760321	MV411	viability	CCCGGCGCAGTGCCAAAATTGG	PRICKLE2	ENSG00000163637	0.44544390360222397	[315,241]	[255,237]	3	hSpCas9	negative selection	4597429
64157313	64157335	3	-	27760321	MV411	viability	CTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	1.1417586010221188	[772,706]	[1180,920]	8	hSpCas9	negative selection	4597430
64159988	64160010	3	-	27760321	MV411	viability	ACGCGAAAACTTGGGCCGCGGG	PRICKLE2	ENSG00000163637	1.0780768356385353	[886,715]	[1273,864]	7	hSpCas9	negative selection	4597431
64160056	64160078	3	-	27760321	MV411	viability	GTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.5345277175115171	[669,575]	[785,304]	4	hSpCas9	negative selection	4597432
64147380	64147402	3	+	27760321	HL60	viability	GTCTACGTCGGCTGACAGCCGG	PRICKLE2	ENSG00000163637	-0.22609391610700988	[524,459]	[333,352]	-3	hSpCas9	negative selection	4680891
64147468	64147490	3	-	27760321	HL60	viability	CCCGGCGCAGTGCCAAAATTGG	PRICKLE2	ENSG00000163637	0.3391375407796442	[315,241]	[322,246]	4	hSpCas9	negative selection	4680892
64157313	64157335	3	-	27760321	HL60	viability	CTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	-1.0851861205580602	[772,706]	[294,273]	-8	hSpCas9	negative selection	4680893
64159988	64160010	3	-	27760321	HL60	viability	ACGCGAAAACTTGGGCCGCGGG	PRICKLE2	ENSG00000163637	0.1975734237865261	[886,715]	[703,791]	2	hSpCas9	negative selection	4680894
64160056	64160078	3	-	27760321	HL60	viability	GTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.61238347751206	[669,575]	[378,281]	-6	hSpCas9	negative selection	4680895
64147380	64147402	3	+	27760321	HT1080	viability	GTCTACGTCGGCTGACAGCCGG	PRICKLE2	ENSG00000163637	1.0987098897102663	[459,358]	[451,236]	6	hSpCas9	negative selection	4764354
64147468	64147490	3	-	27760321	HT1080	viability	CCCGGCGCAGTGCCAAAATTGG	PRICKLE2	ENSG00000163637	1.3656155799075949	[241,188]	[204,238]	7	hSpCas9	negative selection	4764355
64157313	64157335	3	-	27760321	HT1080	viability	CTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	-0.9616657950181491	[706,551]	[165,87]	-4	hSpCas9	negative selection	4764356
64159988	64160010	3	-	27760321	HT1080	viability	ACGCGAAAACTTGGGCCGCGGG	PRICKLE2	ENSG00000163637	0.42464684984154144	[715,558]	[348,331]	2	hSpCas9	negative selection	4764357
64160056	64160078	3	-	27760321	HT1080	viability	GTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.15401417589040395	[575,449]	[176,190]	0	hSpCas9	negative selection	4764358
64147380	64147402	3	+	27760321	HT29	viability after 7 days	GTCTACGTCGGCTGACAGCCGG	PRICKLE2	ENSG00000163637	-0.030325129751658797	[459,358]	[522,636,390]	0	hSpCas9	negative selection	4847817
64147468	64147490	3	-	27760321	HT29	viability after 7 days	CCCGGCGCAGTGCCAAAATTGG	PRICKLE2	ENSG00000163637	0.5571693273905107	[241,188]	[490,323,418]	8	hSpCas9	negative selection	4847818
64157313	64157335	3	-	27760321	HT29	viability after 7 days	CTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	-1.1254952502206672	[706,551]	[509,212,407]	-8	hSpCas9	negative selection	4847819
64159988	64160010	3	-	27760321	HT29	viability after 7 days	ACGCGAAAACTTGGGCCGCGGG	PRICKLE2	ENSG00000163637	-0.03328766211938383	[715,558]	[862,791,756]	0	hSpCas9	negative selection	4847820
64160056	64160078	3	-	27760321	HT29	viability after 7 days	GTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.027712316046761276	[575,449]	[565,696,735]	0	hSpCas9	negative selection	4847821
64147380	64147402	3	+	27760321	HT29	viability after 25 days	GTCTACGTCGGCTGACAGCCGG	PRICKLE2	ENSG00000163637	0.2777583834213474	[459,358]	[585,537,576]	3	hSpCas9	negative selection	4931280
64147468	64147490	3	-	27760321	HT29	viability after 25 days	CCCGGCGCAGTGCCAAAATTGG	PRICKLE2	ENSG00000163637	0.6471988507226645	[241,188]	[244,391,544]	7	hSpCas9	negative selection	4931281
64157313	64157335	3	-	27760321	HT29	viability after 25 days	CTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	-0.5362911880653547	[706,551]	[587,480,402]	-5	hSpCas9	negative selection	4931282
64159988	64160010	3	-	27760321	HT29	viability after 25 days	ACGCGAAAACTTGGGCCGCGGG	PRICKLE2	ENSG00000163637	0.6002090730397187	[715,558]	[1097,1101,1112]	6	hSpCas9	negative selection	4931283
64160056	64160078	3	-	27760321	HT29	viability after 25 days	GTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.12822059423566923	[575,449]	[397,727,485]	-1	hSpCas9	negative selection	4931284
64147380	64147402	3	+	27760321	HT29	viability after 22 days	GTCTACGTCGGCTGACAGCCGG	PRICKLE2	ENSG00000163637	0.24133567416026147	[459,358]	[484,614,580]	2	hSpCas9	negative selection	5014743
64147468	64147490	3	-	27760321	HT29	viability after 22 days	CCCGGCGCAGTGCCAAAATTGG	PRICKLE2	ENSG00000163637	0.43321277483996196	[241,188]	[302,378,327]	5	hSpCas9	negative selection	5014744
64157313	64157335	3	-	27760321	HT29	viability after 22 days	CTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	-0.47568864107376546	[706,551]	[362,618,592]	-4	hSpCas9	negative selection	5014745
64159988	64160010	3	-	27760321	HT29	viability after 22 days	ACGCGAAAACTTGGGCCGCGGG	PRICKLE2	ENSG00000163637	0.766362922387319	[715,558]	[1863,970,905]	8	hSpCas9	negative selection	5014746
64160056	64160078	3	-	27760321	HT29	viability after 22 days	GTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.033464715590708405	[575,449]	[649,754,412]	0	hSpCas9	negative selection	5014747
64147380	64147402	3	+	27760321	HT29	viability after 19 days	GTCTACGTCGGCTGACAGCCGG	PRICKLE2	ENSG00000163637	0.46536030915184445	[459,358]	[602,662,667]	4	hSpCas9	negative selection	5098206
64147468	64147490	3	-	27760321	HT29	viability after 19 days	CCCGGCGCAGTGCCAAAATTGG	PRICKLE2	ENSG00000163637	0.47121264609689134	[241,188]	[398,348,284]	4	hSpCas9	negative selection	5098207
64157313	64157335	3	-	27760321	HT29	viability after 19 days	CTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	0.13477131980087265	[706,551]	[697,519,1129]	1	hSpCas9	negative selection	5098208
64159988	64160010	3	-	27760321	HT29	viability after 19 days	ACGCGAAAACTTGGGCCGCGGG	PRICKLE2	ENSG00000163637	0.9789444117404005	[715,558]	[1194,1948,1151]	8	hSpCas9	negative selection	5098209
64160056	64160078	3	-	27760321	HT29	viability after 19 days	GTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.4203906432465588	[575,449]	[401,492,416]	-4	hSpCas9	negative selection	5098210
64147380	64147402	3	+	27760321	HT29	viability after 16 days	GTCTACGTCGGCTGACAGCCGG	PRICKLE2	ENSG00000163637	0.17330611074261248	[459,358]	[686,435,444]	1	hSpCas9	negative selection	5181669
64147468	64147490	3	-	27760321	HT29	viability after 16 days	CCCGGCGCAGTGCCAAAATTGG	PRICKLE2	ENSG00000163637	0.5715980720423701	[241,188]	[297,405,363]	6	hSpCas9	negative selection	5181670
64157313	64157335	3	-	27760321	HT29	viability after 16 days	CTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	-0.6945288126955462	[706,551]	[467,458,380]	-6	hSpCas9	negative selection	5181671
64159988	64160010	3	-	27760321	HT29	viability after 16 days	ACGCGAAAACTTGGGCCGCGGG	PRICKLE2	ENSG00000163637	0.5979932376884627	[715,558]	[1055,1054,1125]	7	hSpCas9	negative selection	5181672
64160056	64160078	3	-	27760321	HT29	viability after 16 days	GTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.5078206513602548	[575,449]	[404,444,359]	-5	hSpCas9	negative selection	5181673
64147380	64147402	3	+	27760321	HT29	viability after 13 days	GTCTACGTCGGCTGACAGCCGG	PRICKLE2	ENSG00000163637	-0.2207957005151544	[459,358]	[421,361,436]	-3	hSpCas9	negative selection	5265132
64147468	64147490	3	-	27760321	HT29	viability after 13 days	CCCGGCGCAGTGCCAAAATTGG	PRICKLE2	ENSG00000163637	0.6678674965482214	[241,188]	[331,518,343]	8	hSpCas9	negative selection	5265133
64157313	64157335	3	-	27760321	HT29	viability after 13 days	CTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	-0.42611555715354915	[706,551]	[578,670,389]	-5	hSpCas9	negative selection	5265134
64159988	64160010	3	-	27760321	HT29	viability after 13 days	ACGCGAAAACTTGGGCCGCGGG	PRICKLE2	ENSG00000163637	0.31708031134102455	[715,558]	[719,1234,815]	4	hSpCas9	negative selection	5265135
64160056	64160078	3	-	27760321	HT29	viability after 13 days	GTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.33247971867184933	[575,449]	[451,510,455]	-4	hSpCas9	negative selection	5265136
64147380	64147402	3	+	27760321	HT29	viability after 10 days	GTCTACGTCGGCTGACAGCCGG	PRICKLE2	ENSG00000163637	-0.20297104080358053	[459,358]	[671,412,250]	-3	hSpCas9	negative selection	5348595
64147468	64147490	3	-	27760321	HT29	viability after 10 days	CCCGGCGCAGTGCCAAAATTGG	PRICKLE2	ENSG00000163637	0.5936857595543583	[241,188]	[311,505,402]	7	hSpCas9	negative selection	5348596
64157313	64157335	3	-	27760321	HT29	viability after 10 days	CTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	-0.8587255281459566	[706,551]	[451,340,502]	-7	hSpCas9	negative selection	5348597
64159988	64160010	3	-	27760321	HT29	viability after 10 days	ACGCGAAAACTTGGGCCGCGGG	PRICKLE2	ENSG00000163637	0.44893111102908523	[715,558]	[1277,952,1025]	6	hSpCas9	negative selection	5348598
64160056	64160078	3	-	27760321	HT29	viability after 10 days	GTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.2583557801237368	[575,449]	[775,317,506]	-3	hSpCas9	negative selection	5348599
64147380	64147402	3	+	27760321	MOLM13	viability	GTCTACGTCGGCTGACAGCCGG	PRICKLE2	ENSG00000163637	1.715914124274866	[524,459]	[858,954]	9	hSpCas9	negative selection	5432058
64147468	64147490	3	-	27760321	MOLM13	viability	CCCGGCGCAGTGCCAAAATTGG	PRICKLE2	ENSG00000163637	1.7296833567244976	[315,241]	[953,146]	9	hSpCas9	negative selection	5432059
64157313	64157335	3	-	27760321	MOLM13	viability	CTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	-0.52546328663645	[772,706]	[404,191]	-3	hSpCas9	negative selection	5432060
64159988	64160010	3	-	27760321	MOLM13	viability	ACGCGAAAACTTGGGCCGCGGG	PRICKLE2	ENSG00000163637	0.6823466868230266	[886,715]	[792,660]	5	hSpCas9	negative selection	5432061
64160056	64160078	3	-	27760321	MOLM13	viability	GTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.02220047672881087	[669,575]	[336,371]	0	hSpCas9	negative selection	5432062
64159989	64160012	3	-	27260156	BXPC3	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.042626066795297346	[282]	[201,267,308,391]	-1	hSpCas9	negative selection	5564568
64153257	64153280	3	-	27260156	BXPC3	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	-0.0727799284591708	[210]	[179,226,173,264]	-2	hSpCas9	negative selection	5564569
64160056	64160079	3	-	27260156	BXPC3	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.12439304040546928	[717]	[790,770,783,941]	2	hSpCas9	negative selection	5564570
64153254	64153277	3	+	27260156	BXPC3	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.027364148206420413	[663]	[721,651,659,803]	0	hSpCas9	negative selection	5628827
64163071	64163094	3	-	27260156	BXPC3	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.1683544419569063	[807]	[642,873,1085,1267]	3	hSpCas9	negative selection	5628828
64159989	64160012	3	-	27260156	A673	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.23894203088442645	[282]	[423,436,335,408]	5	hSpCas9	negative selection	5685819
64153257	64153280	3	-	27260156	A673	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.37200708903510427	[210]	[405,217,331,368]	8	hSpCas9	negative selection	5685820
64160056	64160079	3	-	27260156	A673	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.026649921334757742	[717]	[864,884,793,840]	0	hSpCas9	negative selection	5685821
64153254	64153277	3	+	27260156	A673	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.01753351992539076	[663]	[847,758,721,909]	0	hSpCas9	negative selection	5750078
64163071	64163094	3	-	27260156	A673	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.03777823428322458	[807]	[1150,913,842,1100]	0	hSpCas9	negative selection	5750079
64159989	64160012	3	-	27260156	A375	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.05442028192862991	[282]	[286,279,327,453]	0	hSpCas9	negative selection	5807070
64153257	64153280	3	-	27260156	A375	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.3449753857735035	[210]	[256,508,256,260]	5	hSpCas9	negative selection	5807071
64160056	64160079	3	-	27260156	A375	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.036025987411081206	[717]	[894,1062,771,747]	0	hSpCas9	negative selection	5807072
64153254	64153277	3	+	27260156	A375	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.25980955373413583	[663]	[729,839,575,488]	-4	hSpCas9	negative selection	5871329
64163071	64163094	3	-	27260156	A375	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.1409022043578454	[807]	[934,1232,1158,876]	2	hSpCas9	negative selection	5871330
64159989	64160012	3	-	27260156	COLO741	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.0601293737994244	[282]	[342,357,338]	-1	hSpCas9	negative selection	5928321
64153257	64153280	3	-	27260156	COLO741	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.5433329784651472	[210]	[498,439,257]	9	hSpCas9	negative selection	5928322
64160056	64160079	3	-	27260156	COLO741	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.05481949155982202	[717]	[845,1218,794]	1	hSpCas9	negative selection	5928323
64153254	64153277	3	+	27260156	COLO741	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.014225872779667692	[663]	[1231,537,784]	0	hSpCas9	negative selection	5992580
64163071	64163094	3	-	27260156	COLO741	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.04905459087577857	[807]	[1251,1243,745]	1	hSpCas9	negative selection	5992581
64159989	64160012	3	-	27260156	CAL120	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.2009298272066845	[282]	[497,368,361]	3	hSpCas9	negative selection	6049572
64153257	64153280	3	-	27260156	CAL120	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.6123883083809797	[210]	[499,155,559]	8	hSpCas9	negative selection	6049573
64160056	64160079	3	-	27260156	CAL120	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.02867602696046445	[717]	[1187,707,779]	0	hSpCas9	negative selection	6049574
64153254	64153277	3	+	27260156	CAL120	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.18431760257103835	[663]	[1032,453,739]	-3	hSpCas9	negative selection	6113831
64163071	64163094	3	-	27260156	CAL120	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	-0.05932406063088347	[807]	[1172,1023,732]	-1	hSpCas9	negative selection	6113832
64159989	64160012	3	-	27260156	CADOES1	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.0845517712535635	[282]	[233,309,230,343]	1	hSpCas9	negative selection	6170823
64153257	64153280	3	-	27260156	CADOES1	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.44931227574895316	[210]	[170,359,278,261]	7	hSpCas9	negative selection	6170824
64160056	64160079	3	-	27260156	CADOES1	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.027457191690682947	[717]	[851,546,762,554]	0	hSpCas9	negative selection	6170825
64153254	64153277	3	+	27260156	CADOES1	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.08831730971706064	[663]	[642,854,590,532]	1	hSpCas9	negative selection	6235082
64163071	64163094	3	-	27260156	CADOES1	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.04782823281910875	[807]	[711,784,691,923]	0	hSpCas9	negative selection	6235083
64159989	64160012	3	-	27260156	EWS502	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.030732858427554577	[282]	[251,324,313,284]	0	hSpCas9	negative selection	6292074
64153257	64153280	3	-	27260156	EWS502	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.16460411942892972	[210]	[264,215,219,302]	3	hSpCas9	negative selection	6292075
64160056	64160079	3	-	27260156	EWS502	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.06925621833712825	[717]	[776,794,715,909]	1	hSpCas9	negative selection	6292076
64153254	64153277	3	+	27260156	EWS502	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.12024667472544343	[663]	[576,857,590,551]	-2	hSpCas9	negative selection	6356333
64163071	64163094	3	-	27260156	EWS502	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.2662333507482677	[807]	[681,1023,1150,1320]	4	hSpCas9	negative selection	6356334
64159989	64160012	3	-	27260156	EW8	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.292854650652668	[282]	[284,137,144,197]	-5	hSpCas9	negative selection	6413325
64153257	64153280	3	-	27260156	EW8	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.3079900402437037	[210]	[286,284,116,181]	5	hSpCas9	negative selection	6413326
64160056	64160079	3	-	27260156	EW8	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.07050983954894974	[717]	[992,431,466,385]	-1	hSpCas9	negative selection	6413327
64153254	64153277	3	+	27260156	EW8	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.22955257079351638	[663]	[633,469,352,414]	-4	hSpCas9	negative selection	6477584
64163071	64163094	3	-	27260156	EW8	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	-0.06056411459859268	[807]	[645,721,534,624]	-1	hSpCas9	negative selection	6477585
64159989	64160012	3	-	27260156	CORL105	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.146397234403433	[282]	[339,332,490,321]	2	hSpCas9	negative selection	6534576
64153257	64153280	3	-	27260156	CORL105	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.4316062931543646	[210]	[319,302,373,341]	7	hSpCas9	negative selection	6534577
64160056	64160079	3	-	27260156	CORL105	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.1082703995178288	[717]	[732,783,929,693]	-2	hSpCas9	negative selection	6534578
64153254	64153277	3	+	27260156	CORL105	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.12690362277858003	[663]	[590,640,994,661]	-2	hSpCas9	negative selection	6598835
64163071	64163094	3	-	27260156	CORL105	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.15065360805686456	[807]	[871,897,1485,1008]	3	hSpCas9	negative selection	6598836
64159989	64160012	3	-	27260156	HS294T	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.3548906028366885	[282]	[188,144,106,107]	5	hSpCas9	negative selection	6655827
64153257	64153280	3	-	27260156	HS294T	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.6333398521948288	[210]	[122,160,88,132]	8	hSpCas9	negative selection	6655828
64160056	64160079	3	-	27260156	HS294T	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.023476665233528093	[717]	[203,311,292,290]	0	hSpCas9	negative selection	6655829
64153254	64153277	3	+	27260156	HS294T	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.06964795331443352	[663]	[212,206,212,369]	-1	hSpCas9	negative selection	6720086
64163071	64163094	3	-	27260156	HS294T	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.23035776888254889	[807]	[329,392,284,477]	3	hSpCas9	negative selection	6720087
64159989	64160012	3	-	27260156	HCC44	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.12848952672652636	[282]	[428,399,384,193]	2	hSpCas9	negative selection	6777078
64153257	64153280	3	-	27260156	HCC44	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.16198686692791575	[210]	[221,323,239,262]	2	hSpCas9	negative selection	6777079
64160056	64160079	3	-	27260156	HCC44	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.05712217970001998	[717]	[737,586,1215,676]	-1	hSpCas9	negative selection	6777080
64153254	64153277	3	+	27260156	HCC44	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.030567144906000876	[663]	[818,874,686,659]	0	hSpCas9	negative selection	6841337
64163071	64163094	3	-	27260156	HCC44	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.19308442275234505	[807]	[809,1371,981,930]	3	hSpCas9	negative selection	6841338
64159989	64160012	3	-	27260156	G402	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.35379878402422926	[282]	[465,425,387,483]	4	hSpCas9	negative selection	6898329
64153257	64153280	3	-	27260156	G402	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.5111931398882746	[210]	[582,258,212,432]	6	hSpCas9	negative selection	6898330
64160056	64160079	3	-	27260156	G402	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.3307271770600354	[717]	[1497,679,652,1580]	4	hSpCas9	negative selection	6898331
64153254	64153277	3	+	27260156	G402	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.3625768854643643	[663]	[1928,671,765,908]	4	hSpCas9	negative selection	6962588
64163071	64163094	3	-	27260156	G402	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.5301345305146516	[807]	[1622,1463,1113,1514]	6	hSpCas9	negative selection	6962589
64159989	64160012	3	-	27260156	L33	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.048687444710581396	[282]	[228,159,157,224]	-1	hSpCas9	negative selection	7019580
64153257	64153280	3	-	27260156	L33	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.6144271185403569	[210]	[322,136,251,234]	9	hSpCas9	negative selection	7019581
64160056	64160079	3	-	27260156	L33	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.10687722455375115	[717]	[702,379,465,722]	2	hSpCas9	negative selection	7019582
64153254	64153277	3	+	27260156	L33	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.05070863762672584	[663]	[580,328,373,586]	-1	hSpCas9	negative selection	7083839
64163071	64163094	3	-	27260156	L33	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	-0.028716768346605526	[807]	[766,341,446,854]	0	hSpCas9	negative selection	7083840
64159989	64160012	3	-	27260156	K562	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.32890045124076506	[282]	[87,659,300,221]	4	hSpCas9	negative selection	7140831
64153257	64153280	3	-	27260156	K562	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	-0.05325375835474966	[210]	[199,196,206,125]	0	hSpCas9	negative selection	7140832
64160056	64160079	3	-	27260156	K562	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.18506459433790556	[717]	[457,1082,734,626]	2	hSpCas9	negative selection	7140833
64153254	64153277	3	+	27260156	K562	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.15859511140929516	[663]	[788,707,604,551]	2	hSpCas9	negative selection	7205090
64163071	64163094	3	-	27260156	K562	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.15208681490680087	[807]	[1047,628,651,858]	1	hSpCas9	negative selection	7205091
64159989	64160012	3	-	27260156	HT29	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.2353527376491466	[282]	[446,387,461,330]	4	hSpCas9	negative selection	7262082
64153257	64153280	3	-	27260156	HT29	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.17999554162312748	[210]	[275,268,238,363]	3	hSpCas9	negative selection	7262083
64160056	64160079	3	-	27260156	HT29	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.17697316528232732	[717]	[1112,1042,746,1043]	3	hSpCas9	negative selection	7262084
64153254	64153277	3	+	27260156	HT29	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.1630051996794996	[663]	[881,690,600,714]	-3	hSpCas9	negative selection	7326341
64163071	64163094	3	-	27260156	HT29	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.1600556727315573	[807]	[1187,1159,1099,962]	3	hSpCas9	negative selection	7326342
64159989	64160012	3	-	27260156	MHHES1	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.9469400442114213	[282]	[473,1552,336,243]	9	hSpCas9	negative selection	7383333
64153257	64153280	3	-	27260156	MHHES1	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.6757627883054409	[210]	[362,475,374,317]	9	hSpCas9	negative selection	7383334
64160056	64160079	3	-	27260156	MHHES1	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.32562165054580827	[717]	[1180,926,1238,756]	6	hSpCas9	negative selection	7383335
64153254	64153277	3	+	27260156	MHHES1	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.003960123603409804	[663]	[900,595,764,727]	0	hSpCas9	negative selection	7447592
64163071	64163094	3	-	27260156	MHHES1	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.41632132229506125	[807]	[1617,1080,1192,1018]	7	hSpCas9	negative selection	7447593
64159989	64160012	3	-	27260156	MEWO	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.04139624748948523	[282]	[202,308,248]	-1	hSpCas9	negative selection	7504584
64153257	64153280	3	-	27260156	MEWO	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.44046144305171886	[210]	[401,180,246]	8	hSpCas9	negative selection	7504585
64160056	64160079	3	-	27260156	MEWO	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.052267086405246355	[717]	[862,623,634]	1	hSpCas9	negative selection	7504586
64153254	64153277	3	+	27260156	MEWO	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.10560609243134567	[663]	[788,543,695]	2	hSpCas9	negative selection	7568843
64163071	64163094	3	-	27260156	MEWO	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.15354764330428228	[807]	[1004,655,893]	3	hSpCas9	negative selection	7568844
64159989	64160012	3	-	27260156	LNCAPCLONEFGC	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.5485401862327809	[282]	[520,232,279,457]	8	hSpCas9	negative selection	7625835
64153257	64153280	3	-	27260156	LNCAPCLONEFGC	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.5562911846062552	[210]	[152,212,428,357]	8	hSpCas9	negative selection	7625836
64160056	64160079	3	-	27260156	LNCAPCLONEFGC	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.15887770158596015	[717]	[546,747,981,666]	2	hSpCas9	negative selection	7625837
64153254	64153277	3	+	27260156	LNCAPCLONEFGC	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.03892151842834396	[663]	[556,501,594,694]	0	hSpCas9	negative selection	7690094
64163071	64163094	3	-	27260156	LNCAPCLONEFGC	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.2204687398121692	[807]	[830,877,1025,699]	3	hSpCas9	negative selection	7690095
64159989	64160012	3	-	27260156	PANC0327	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.49945069569787626	[282]	[436,251,166,584]	7	hSpCas9	negative selection	7747086
64153257	64153280	3	-	27260156	PANC0327	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	-0.28803612252869426	[210]	[56,177,203,163]	-4	hSpCas9	negative selection	7747087
64160056	64160079	3	-	27260156	PANC0327	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.1852418653166792	[717]	[941,360,644,1016]	2	hSpCas9	negative selection	7747088
64153254	64153277	3	+	27260156	PANC0327	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.03223847927890111	[663]	[742,419,623,553]	0	hSpCas9	negative selection	7811345
64163071	64163094	3	-	27260156	PANC0327	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.024331273051791946	[807]	[1005,631,730,585]	0	hSpCas9	negative selection	7811346
64159989	64160012	3	-	27260156	NCIH2009	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.7260818651375837	[282]	[738,587,651]	8	hSpCas9	negative selection	7868337
64153257	64153280	3	-	27260156	NCIH2009	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.7291729709775385	[210]	[633,430,429]	8	hSpCas9	negative selection	7868338
64160056	64160079	3	-	27260156	NCIH2009	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.2397862677202648	[717]	[1397,1339,852]	3	hSpCas9	negative selection	7868339
64153254	64153277	3	+	27260156	NCIH2009	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.13897018962858276	[663]	[868,751,911]	-2	hSpCas9	negative selection	7932596
64163071	64163094	3	-	27260156	NCIH2009	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	-0.318843458218017	[807]	[927,858,931]	-4	hSpCas9	negative selection	7932597
64159989	64160012	3	-	27260156	NCIH1373	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.9391400629813179	[282]	[525,630,643,160]	8	hSpCas9	negative selection	7989588
64153257	64153280	3	-	27260156	NCIH1373	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.692692896291697	[210]	[372,314,318,140]	7	hSpCas9	negative selection	7989589
64160056	64160079	3	-	27260156	NCIH1373	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.19661228363324634	[717]	[1024,388,929,379]	2	hSpCas9	negative selection	7989590
64153254	64153277	3	+	27260156	NCIH1373	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.0008480194421262577	[663]	[751,917,730,141]	0	hSpCas9	negative selection	8053847
64163071	64163094	3	-	27260156	NCIH1373	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.4473442391199387	[807]	[1806,773,844,441]	4	hSpCas9	negative selection	8053848
64159989	64160012	3	-	27260156	PATU8902	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.6696613243096817	[282]	[439,785,325,1086]	7	hSpCas9	negative selection	8110839
64153257	64153280	3	-	27260156	PATU8902	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.2617952438090797	[210]	[283,366,255,548]	2	hSpCas9	negative selection	8110840
64160056	64160079	3	-	27260156	PATU8902	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.0726264617487048	[717]	[864,836,1223,778]	0	hSpCas9	negative selection	8110841
64153254	64153277	3	+	27260156	PATU8902	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.01879042379762841	[663]	[1014,716,839,1225]	0	hSpCas9	negative selection	8175098
64163071	64163094	3	-	27260156	PATU8902	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.19969286355695193	[807]	[1252,2159,748,1120]	2	hSpCas9	negative selection	8175099
64159989	64160012	3	-	27260156	PANC1	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.8664399037973174	[282]	[326,754,406,356]	9	hSpCas9	negative selection	8232090
64153257	64153280	3	-	27260156	PANC1	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.4613746806561998	[210]	[308,283,209,203]	7	hSpCas9	negative selection	8232091
64160056	64160079	3	-	27260156	PANC1	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.29512701884375925	[717]	[518,617,461,436]	-5	hSpCas9	negative selection	8232092
64153254	64153277	3	+	27260156	PANC1	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.06397819383006004	[663]	[589,719,493,423]	-1	hSpCas9	negative selection	8296349
64163071	64163094	3	-	27260156	PANC1	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	-0.1511476256634421	[807]	[626,649,696,535]	-2	hSpCas9	negative selection	8296350
64159989	64160012	3	-	27260156	PANC0813	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.017992820177015312	[282]	[372,459,189,325]	0	hSpCas9	negative selection	8353341
64153257	64153280	3	-	27260156	PANC0813	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.42394448922969674	[210]	[389,332,423,195]	6	hSpCas9	negative selection	8353342
64160056	64160079	3	-	27260156	PANC0813	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.16279497528056797	[717]	[960,1229,675,909]	2	hSpCas9	negative selection	8353343
64153254	64153277	3	+	27260156	PANC0813	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.10658350493696334	[663]	[876,766,888,828]	1	hSpCas9	negative selection	8417600
64163071	64163094	3	-	27260156	PANC0813	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	-0.014497576546525948	[807]	[1086,815,883,980]	0	hSpCas9	negative selection	8417601
64159989	64160012	3	-	27260156	RDES	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.13867460465236292	[282]	[302,198,418,562]	2	hSpCas9	negative selection	8474592
64153257	64153280	3	-	27260156	RDES	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.4265467695797077	[210]	[252,329,345,391]	6	hSpCas9	negative selection	8474593
64160056	64160079	3	-	27260156	RDES	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.03135243553894895	[717]	[645,831,742,1053]	0	hSpCas9	negative selection	8474594
64153254	64153277	3	+	27260156	RDES	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.029333018361409002	[663]	[526,719,967,978]	0	hSpCas9	negative selection	8538851
64163071	64163094	3	-	27260156	RDES	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.04103877042213	[807]	[751,959,983,1177]	0	hSpCas9	negative selection	8538852
64159989	64160012	3	-	27260156	PC3	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.07718368011107479	[282]	[138,192,513,362]	-2	hSpCas9	negative selection	8595843
64153257	64153280	3	-	27260156	PC3	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.6247625817419352	[210]	[168,241,622,430]	9	hSpCas9	negative selection	8595844
64160056	64160079	3	-	27260156	PC3	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.13160055366268142	[717]	[510,803,1043,922]	3	hSpCas9	negative selection	8595845
64153254	64153277	3	+	27260156	PC3	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.16313444581812553	[663]	[395,571,1477,912]	3	hSpCas9	negative selection	8660102
64163071	64163094	3	-	27260156	PC3	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.1660723788035	[807]	[615,932,1479,835]	4	hSpCas9	negative selection	8660103
64159989	64160012	3	-	27260156	PATU8988T	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.2993977906075661	[282]	[146,231,148,374]	-5	hSpCas9	negative selection	8717094
64153257	64153280	3	-	27260156	PATU8988T	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.3441883540847187	[210]	[285,207,181,363]	6	hSpCas9	negative selection	8717095
64160056	64160079	3	-	27260156	PATU8988T	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.4015088780653384	[717]	[836,1018,1013,793]	6	hSpCas9	negative selection	8717096
64153254	64153277	3	+	27260156	PATU8988T	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.15865437411037558	[663]	[444,556,634,666]	-3	hSpCas9	negative selection	8781353
64163071	64163094	3	-	27260156	PATU8988T	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.16270042351500424	[807]	[684,1077,650,1123]	3	hSpCas9	negative selection	8781354
64159989	64160012	3	-	27260156	T47D	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.12593632215120054	[282]	[320,314,451,352]	2	hSpCas9	negative selection	8838345
64153257	64153280	3	-	27260156	T47D	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.21492873668660595	[210]	[235,261,292,353]	4	hSpCas9	negative selection	8838346
64160056	64160079	3	-	27260156	T47D	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.12022943207960102	[717]	[936,815,887,1006]	2	hSpCas9	negative selection	8838347
64153254	64153277	3	+	27260156	T47D	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.011458932267939037	[663]	[848,670,766,791]	0	hSpCas9	negative selection	8902604
64163071	64163094	3	-	27260156	T47D	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.12604226238670646	[807]	[1087,993,985,1044]	2	hSpCas9	negative selection	8902605
64159989	64160012	3	-	27260156	SU8686	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.02866664533153207	[282]	[220,238,400,246]	0	hSpCas9	negative selection	8959596
64153257	64153280	3	-	27260156	SU8686	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.29697564941877397	[210]	[252,291,236,235]	5	hSpCas9	negative selection	8959597
64160056	64160079	3	-	27260156	SU8686	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.20408761740028125	[717]	[835,677,770,1039]	3	hSpCas9	negative selection	8959598
64153254	64153277	3	+	27260156	SU8686	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.183187400803216	[663]	[517,590,632,579]	-3	hSpCas9	negative selection	9023855
64163071	64163094	3	-	27260156	SU8686	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.16978122078528224	[807]	[795,888,971,966]	3	hSpCas9	negative selection	9023856
64159989	64160012	3	-	27260156	SKES1	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.027305965372683594	[282]	[354,271,251,240]	0	hSpCas9	negative selection	9080847
64153257	64153280	3	-	27260156	SKES1	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.32620969531236266	[210]	[309,284,229,239]	6	hSpCas9	negative selection	9080848
64160056	64160079	3	-	27260156	SKES1	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.0025719985439491833	[717]	[746,844,732,573]	0	hSpCas9	negative selection	9080849
64153254	64153277	3	+	27260156	SKES1	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.08628510756769714	[663]	[751,969,558,579]	2	hSpCas9	negative selection	9145106
64163071	64163094	3	-	27260156	SKES1	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.25882620025319536	[807]	[1262,947,848,842]	5	hSpCas9	negative selection	9145107
64159989	64160012	3	-	27260156	TOV112D	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.15698519449161208	[282]	[241,340,310,367]	3	hSpCas9	negative selection	9202098
64153257	64153280	3	-	27260156	TOV112D	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.857682081074965	[210]	[423,234,520,319]	9	hSpCas9	negative selection	9202099
64160056	64160079	3	-	27260156	TOV112D	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.1192615205887928	[717]	[705,843,533,612]	-2	hSpCas9	negative selection	9202100
64153254	64153277	3	+	27260156	TOV112D	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	0.014335363219906139	[663]	[778,899,479,593]	0	hSpCas9	negative selection	9266357
64163071	64163094	3	-	27260156	TOV112D	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.03368871702406773	[807]	[940,1023,766,642]	0	hSpCas9	negative selection	9266358
64159989	64160012	3	-	27260156	TC71	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	-0.05376475874455611	[282]	[290,300,267,310]	-1	hSpCas9	negative selection	9323349
64153257	64153280	3	-	27260156	TC71	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.2576886532431537	[210]	[223,302,226,333]	6	hSpCas9	negative selection	9323350
64160056	64160079	3	-	27260156	TC71	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	-0.0006868262642802936	[717]	[638,770,834,836]	0	hSpCas9	negative selection	9323351
64153254	64153277	3	+	27260156	TC71	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.17078664399013677	[663]	[549,691,687,596]	-4	hSpCas9	negative selection	9387608
64163071	64163094	3	-	27260156	TC71	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	0.16100152347932684	[807]	[989,930,977,973]	4	hSpCas9	negative selection	9387609
64159989	64160012	3	-	27260156	TC32	viability	AAACGCGAAAACTTGGGCCGCGG	PRICKLE2	ENSG00000163637	0.1873101488340836	[282]	[302,253,386,279]	3	hSpCas9	negative selection	9444600
64153257	64153280	3	-	27260156	TC32	viability	CGGCCAGCGCTACATCATGAAGG	PRICKLE2	ENSG00000163637	0.08596528889839039	[210]	[166,190,294,202]	1	hSpCas9	negative selection	9444601
64160056	64160079	3	-	27260156	TC32	viability	GGTTCGATATTGCAACTCCCTGG	PRICKLE2	ENSG00000163637	0.079705012068649	[717]	[696,571,923,706]	1	hSpCas9	negative selection	9444602
64153254	64153277	3	+	27260156	TC32	viability	CCTCCTTCATGATGTAGCGCTGG	PRICKLE2	ENSG00000163637	-0.2961536216775422	[663]	[404,396,584,694]	-5	hSpCas9	negative selection	9508859
64163071	64163094	3	-	27260156	TC32	viability	GTCCCTTATGTCAACAGTCCTGG	PRICKLE2	ENSG00000163637	-0.028688725872841214	[807]	[564,602,984,907]	0	hSpCas9	negative selection	9508860
64153253	64153276	3	-	27869803	HPAFII	viability after 27 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	-0.7977241249528441	[406]	[145,103,NaN]	-5	hSpCas9	negative selection	9586000
64157272	64157295	3	+	27869803	HPAFII	viability after 27 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	0.8680794426270415	[8]	[0,14,NaN]	7	hSpCas9	negative selection	9586001
64159972	64159995	3	+	27869803	HPAFII	viability after 27 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	1.995395838603275	[16]	[75,1,NaN]	9	hSpCas9	negative selection	9586002
64153253	64153276	3	-	27869803	HPAFII	viability after 15 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	-0.9476476237449387	[406]	[293,184,NaN]	-7	hSpCas9	negative selection	9668449
64157272	64157295	3	+	27869803	HPAFII	viability after 15 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	2.391813272155365	[8]	[14,72,NaN]	9	hSpCas9	negative selection	9668450
64159972	64159995	3	+	27869803	HPAFII	viability after 15 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.6288771725407076	[16]	[55,10,NaN]	7	hSpCas9	negative selection	9668451
64153253	64153276	3	-	27869803	ASPC1	viability after 36 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	0.4393901995696427	[873]	[1090,253,60]	4	hSpCas9	negative selection	9750898
64157272	64157295	3	+	27869803	ASPC1	viability after 36 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	-0.570936132618814	[179]	[58,78,0]	-5	hSpCas9	negative selection	9750899
64159972	64159995	3	+	27869803	ASPC1	viability after 36 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.21551358227541506	[104]	[51,85,0]	2	hSpCas9	negative selection	9750900
64153253	64153276	3	-	27869803	PATU8988S	viability after 35 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	-0.01788254427915692	[668]	[318,212,NaN]	0	hSpCas9	negative selection	9833347
64157272	64157295	3	+	27869803	PATU8988S	viability after 35 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	0.8815503520475138	[150]	[130,92,NaN]	8	hSpCas9	negative selection	9833348
64159972	64159995	3	+	27869803	PATU8988S	viability after 35 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.3622128560130107	[85]	[53,34,NaN]	4	hSpCas9	negative selection	9833349
64153253	64153276	3	-	27869803	PATU8988S	viability after 31 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	-0.488352048731452	[668]	[172,211,NaN]	-5	hSpCas9	negative selection	9915796
64157272	64157295	3	+	27869803	PATU8988S	viability after 31 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	0.7318859273554723	[150]	[88,113,NaN]	8	hSpCas9	negative selection	9915797
64159972	64159995	3	+	27869803	PATU8988S	viability after 31 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.9322012944743265	[85]	[42,93,NaN]	9	hSpCas9	negative selection	9915798
64153253	64153276	3	-	27869803	HPAFII	viability after 35 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	-1.1706915647350031	[406]	[83,99,NaN]	-6	hSpCas9	negative selection	9998245
64157272	64157295	3	+	27869803	HPAFII	viability after 35 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	1.1249389112805601	[8]	[0,19,NaN]	7	hSpCas9	negative selection	9998246
64159972	64159995	3	+	27869803	HPAFII	viability after 35 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	1.2213926817816483	[16]	[36,0,NaN]	7	hSpCas9	negative selection	9998247
64153253	64153276	3	-	27869803	HPAFII	viability after 31 days	CAGCGCTACATCATGAAGGAGGG	PRICKLE2	ENSG00000163637	-0.48602718206019235	[406]	[164,160,NaN]	-3	hSpCas9	negative selection	10080694
64157272	64157295	3	+	27869803	HPAFII	viability after 31 days	CAGTGCATACGAAGCACGGCGGG	PRICKLE2	ENSG00000163637	2.6896139126001164	[8]	[0,66,NaN]	9	hSpCas9	negative selection	10080695
64159972	64159995	3	+	27869803	HPAFII	viability after 31 days	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	2.1625551105654193	[16]	[80,0,NaN]	9	hSpCas9	negative selection	10080696
64157290	64157313	3	+	28162770	P31FUJ	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	0.16574717207589607	[87]	[115]	1	hSpCas9	negative selection	10216863
64147157	64147180	3	+	28162770	P31FUJ	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	0.7884142814953172	[269]	[547]	8	hSpCas9	negative selection	10216864
64147062	64147085	3	-	28162770	P31FUJ	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	0.2598561919869391	[198]	[279]	3	hSpCas9	negative selection	10216865
64159972	64159995	3	+	28162770	P31FUJ	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.14106305398298624	[310]	[402]	1	hSpCas9	negative selection	10216866
64157313	64157336	3	-	28162770	P31FUJ	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	1.0806143906174663	[203]	[506]	9	hSpCas9	negative selection	10216867
64157271	64157294	3	+	28162770	P31FUJ	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	1.5041633897518274	[17]	[59]	9	hSpCas9	negative selection	10216868
64157211	64157234	3	-	28162770	P31FUJ	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	-1.5091334328616302	[108]	[44]	-7	hSpCas9	negative selection	10216869
64153215	64153238	3	+	28162770	P31FUJ	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.49149697791566704	[571]	[944]	5	hSpCas9	negative selection	10216870
64147595	64147618	3	+	28162770	P31FUJ	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	-0.16898710681693535	[198]	[207]	-2	hSpCas9	negative selection	10216871
64147305	64147328	3	-	28162770	P31FUJ	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	-0.031412433430724196	[513]	[590]	0	hSpCas9	negative selection	10216872
64157290	64157313	3	+	28162770	TF1	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	NaN	[NaN]	[199]	1	hSpCas9	negative selection	10386229
64147157	64147180	3	+	28162770	TF1	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	NaN	[NaN]	[209]	1	hSpCas9	negative selection	10386230
64147062	64147085	3	-	28162770	TF1	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10386231
64159972	64159995	3	+	28162770	TF1	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	NaN	[NaN]	[379]	1	hSpCas9	negative selection	10386232
64157313	64157336	3	-	28162770	TF1	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	NaN	[NaN]	[248]	1	hSpCas9	negative selection	10386233
64157271	64157294	3	+	28162770	TF1	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10386234
64157211	64157234	3	-	28162770	TF1	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10386235
64153215	64153238	3	+	28162770	TF1	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	NaN	[NaN]	[712]	1	hSpCas9	negative selection	10386236
64147595	64147618	3	+	28162770	TF1	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	NaN	[NaN]	[228]	1	hSpCas9	negative selection	10386237
64147305	64147328	3	-	28162770	TF1	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	NaN	[NaN]	[398]	1	hSpCas9	negative selection	10386238
64157290	64157313	3	+	28162770	SKM1	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	-0.9855004303048849	[27]	[24]	-6	hSpCas9	negative selection	10555595
64147157	64147180	3	+	28162770	SKM1	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	0.9726793940004881	[48]	[169]	8	hSpCas9	negative selection	10555596
64147062	64147085	3	-	28162770	SKM1	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	0.3177230656446077	[58]	[129]	3	hSpCas9	negative selection	10555597
64159972	64159995	3	+	28162770	SKM1	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.18541577354047745	[96]	[194]	1	hSpCas9	negative selection	10555598
64157313	64157336	3	-	28162770	SKM1	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	0.4442783673154425	[73]	[177]	4	hSpCas9	negative selection	10555599
64157271	64157294	3	+	28162770	SKM1	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	1.499926396865357	[3]	[19]	9	hSpCas9	negative selection	10555600
64157211	64157234	3	-	28162770	SKM1	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	1.28233496179273	[9]	[42]	9	hSpCas9	negative selection	10555601
64153215	64153238	3	+	28162770	SKM1	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.11861975489906262	[123]	[237]	1	hSpCas9	negative selection	10555602
64147595	64147618	3	+	28162770	SKM1	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	-1.319501357492822	[47]	[33]	-7	hSpCas9	negative selection	10555603
64147305	64147328	3	-	28162770	SKM1	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	0.2635740336840684	[89]	[190]	2	hSpCas9	negative selection	10555604
64157290	64157313	3	+	28162770	SKM1	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	-0.9855004303048849	[27]	[24]	-6	hSpCas9	negative selection	10724961
64147157	64147180	3	+	28162770	SKM1	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	0.9726793940004881	[48]	[169]	8	hSpCas9	negative selection	10724962
64147062	64147085	3	-	28162770	SKM1	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	0.3177230656446077	[58]	[129]	3	hSpCas9	negative selection	10724963
64159972	64159995	3	+	28162770	SKM1	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.18541577354047745	[96]	[194]	1	hSpCas9	negative selection	10724964
64157313	64157336	3	-	28162770	SKM1	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	0.4442783673154425	[73]	[177]	4	hSpCas9	negative selection	10724965
64157271	64157294	3	+	28162770	SKM1	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	1.499926396865357	[3]	[19]	9	hSpCas9	negative selection	10724966
64157211	64157234	3	-	28162770	SKM1	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	1.28233496179273	[9]	[42]	9	hSpCas9	negative selection	10724967
64153215	64153238	3	+	28162770	SKM1	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.11861975489906262	[123]	[237]	1	hSpCas9	negative selection	10724968
64147595	64147618	3	+	28162770	SKM1	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	-1.319501357492822	[47]	[33]	-7	hSpCas9	negative selection	10724969
64147305	64147328	3	-	28162770	SKM1	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	0.2635740336840684	[89]	[190]	2	hSpCas9	negative selection	10724970
64157290	64157313	3	+	28162770	PL21	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	0.7113924290274672	[86]	[61]	6	hSpCas9	negative selection	10894327
64147157	64147180	3	+	28162770	PL21	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	1.7851021152104762	[155]	[233]	9	hSpCas9	negative selection	10894328
64147062	64147085	3	-	28162770	PL21	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	-0.6487677970127899	[316]	[87]	-4	hSpCas9	negative selection	10894329
64159972	64159995	3	+	28162770	PL21	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.31084307889553997	[325]	[175]	2	hSpCas9	negative selection	10894330
64157313	64157336	3	-	28162770	PL21	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	1.236665490514434	[233]	[239]	8	hSpCas9	negative selection	10894331
64157271	64157294	3	+	28162770	PL21	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	-0.12178848039804224	[34]	[13]	-1	hSpCas9	negative selection	10894332
64157211	64157234	3	-	28162770	PL21	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	1.166972750554121	[43]	[42]	8	hSpCas9	negative selection	10894333
64153215	64153238	3	+	28162770	PL21	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.03324230574457587	[356]	[158]	0	hSpCas9	negative selection	10894334
64147595	64147618	3	+	28162770	PL21	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	0.3027093481298677	[94]	[50]	2	hSpCas9	negative selection	10894335
64147305	64147328	3	-	28162770	PL21	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	0.1486800151327733	[370]	[178]	1	hSpCas9	negative selection	10894336
64157290	64157313	3	+	28162770	P31FUJ	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	0.16574717207589607	[87]	[115]	1	hSpCas9	negative selection	11063693
64147157	64147180	3	+	28162770	P31FUJ	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	0.7884142814953172	[269]	[547]	8	hSpCas9	negative selection	11063694
64147062	64147085	3	-	28162770	P31FUJ	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	0.2598561919869391	[198]	[279]	3	hSpCas9	negative selection	11063695
64159972	64159995	3	+	28162770	P31FUJ	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.14106305398298624	[310]	[402]	1	hSpCas9	negative selection	11063696
64157313	64157336	3	-	28162770	P31FUJ	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	1.0806143906174663	[203]	[506]	9	hSpCas9	negative selection	11063697
64157271	64157294	3	+	28162770	P31FUJ	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	1.5041633897518274	[17]	[59]	9	hSpCas9	negative selection	11063698
64157211	64157234	3	-	28162770	P31FUJ	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	-1.5091334328616302	[108]	[44]	-7	hSpCas9	negative selection	11063699
64153215	64153238	3	+	28162770	P31FUJ	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.49149697791566704	[571]	[944]	5	hSpCas9	negative selection	11063700
64147595	64147618	3	+	28162770	P31FUJ	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	-0.16898710681693535	[198]	[207]	-2	hSpCas9	negative selection	11063701
64147305	64147328	3	-	28162770	P31FUJ	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	-0.031412433430724196	[513]	[590]	0	hSpCas9	negative selection	11063702
64157290	64157313	3	+	28162770	OCIAML5	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	1.6230183120847859	[24]	[138]	9	hSpCas9	negative selection	11233059
64147157	64147180	3	+	28162770	OCIAML5	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	1.1323027774222385	[115]	[458]	8	hSpCas9	negative selection	11233060
64147062	64147085	3	-	28162770	OCIAML5	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	0.6546288730598959	[100]	[286]	6	hSpCas9	negative selection	11233061
64159972	64159995	3	+	28162770	OCIAML5	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.21931806237276857	[137]	[289]	1	hSpCas9	negative selection	11233062
64157313	64157336	3	-	28162770	OCIAML5	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	0.7463164456194807	[106]	[323]	6	hSpCas9	negative selection	11233063
64157271	64157294	3	+	28162770	OCIAML5	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	1.2259359411372763	[8]	[37]	9	hSpCas9	negative selection	11233064
64157211	64157234	3	-	28162770	OCIAML5	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	-0.03103671190931634	[59]	[105]	0	hSpCas9	negative selection	11233065
64153215	64153238	3	+	28162770	OCIAML5	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.12699409144364004	[346]	[683]	1	hSpCas9	negative selection	11233066
64147595	64147618	3	+	28162770	OCIAML5	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	0.33556043231177435	[107]	[245]	3	hSpCas9	negative selection	11233067
64147305	64147328	3	-	28162770	OCIAML5	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	0.7684274805058164	[253]	[780]	6	hSpCas9	negative selection	11233068
64157290	64157313	3	+	28162770	EOL1	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	-0.8292916411600679	[171]	[50]	-5	hSpCas9	negative selection	11402425
64147157	64147180	3	+	28162770	EOL1	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	1.4633206392716231	[200]	[291]	9	hSpCas9	negative selection	11402426
64147062	64147085	3	-	28162770	EOL1	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	0.47152814144747124	[448]	[327]	4	hSpCas9	negative selection	11402427
64159972	64159995	3	+	28162770	EOL1	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.6180222611425321	[558]	[451]	5	hSpCas9	negative selection	11402428
64157313	64157336	3	-	28162770	EOL1	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	0.702883800156601	[329]	[282]	6	hSpCas9	negative selection	11402429
64157271	64157294	3	+	28162770	EOL1	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	-2.9823428240379837	[74]	[4]	-9	hSpCas9	negative selection	11402430
64157211	64157234	3	-	28162770	EOL1	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	0.981131299936902	[74]	[77]	8	hSpCas9	negative selection	11402431
64153215	64153238	3	+	28162770	EOL1	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.7303522420647387	[531]	[464]	6	hSpCas9	negative selection	11402432
64147595	64147618	3	+	28162770	EOL1	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	-0.2849055940584153	[147]	[63]	-2	hSpCas9	negative selection	11402433
64147305	64147328	3	-	28162770	EOL1	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	0.1937344043859236	[467]	[281]	1	hSpCas9	negative selection	11402434
64157290	64157313	3	+	28162770	MOLM13	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	1.6122792908797534	[94]	[209]	9	hSpCas9	negative selection	11571791
64147157	64147180	3	+	28162770	MOLM13	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	0.9917032267407544	[248]	[357]	7	hSpCas9	negative selection	11571792
64147062	64147085	3	-	28162770	MOLM13	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	1.079556206094789	[338]	[517]	7	hSpCas9	negative selection	11571793
64159972	64159995	3	+	28162770	MOLM13	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.6208229458641196	[464]	[516]	4	hSpCas9	negative selection	11571794
64157313	64157336	3	-	28162770	MOLM13	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	0.969083524573137	[324]	[459]	7	hSpCas9	negative selection	11571795
64157271	64157294	3	+	28162770	MOLM13	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	0.9071744270700999	[58]	[79]	7	hSpCas9	negative selection	11571796
64157211	64157234	3	-	28162770	MOLM13	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	0.45101556298018264	[85]	[84]	3	hSpCas9	negative selection	11571797
64153215	64153238	3	+	28162770	MOLM13	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	-0.24238794809030018	[606]	[370]	-1	hSpCas9	negative selection	11571798
64147595	64147618	3	+	28162770	MOLM13	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	0.11641701104320124	[147]	[115]	0	hSpCas9	negative selection	11571799
64147305	64147328	3	-	28162770	MOLM13	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	0.0037042329366469007	[417]	[302]	0	hSpCas9	negative selection	11571800
64157290	64157313	3	+	28162770	HEL	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	0.2661754805361489	[147]	[113]	2	hSpCas9	negative selection	11741157
64147157	64147180	3	+	28162770	HEL	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	0.4538361557437778	[219]	[192]	4	hSpCas9	negative selection	11741158
64147062	64147085	3	-	28162770	HEL	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	0.6804584979495155	[301]	[309]	6	hSpCas9	negative selection	11741159
64159972	64159995	3	+	28162770	HEL	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.5113130214659901	[378]	[345]	4	hSpCas9	negative selection	11741160
64157313	64157336	3	-	28162770	HEL	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	1.1227317731199709	[265]	[370]	8	hSpCas9	negative selection	11741161
64157271	64157294	3	+	28162770	HEL	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	2.4234258035958813	[38]	[133]	9	hSpCas9	negative selection	11741162
64157211	64157234	3	-	28162770	HEL	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	0.41325698587758963	[67]	[57]	3	hSpCas9	negative selection	11741163
64153215	64153238	3	+	28162770	HEL	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	-0.19268940105153742	[479]	[268]	-1	hSpCas9	negative selection	11741164
64147595	64147618	3	+	28162770	HEL	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	0.08504926142930447	[130]	[88]	0	hSpCas9	negative selection	11741165
64147305	64147328	3	-	28162770	HEL	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	0.3765019941282194	[450]	[374]	3	hSpCas9	negative selection	11741166
64157290	64157313	3	+	28162770	MV411	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	0.8995142473624684	[83]	[131]	7	hSpCas9	negative selection	11910523
64147157	64147180	3	+	28162770	MV411	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	0.007683968784889833	[208]	[176]	0	hSpCas9	negative selection	11910524
64147062	64147085	3	-	28162770	MV411	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	0.7124002753933015	[212]	[293]	6	hSpCas9	negative selection	11910525
64159972	64159995	3	+	28162770	MV411	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	-0.7133918519365469	[326]	[167]	-5	hSpCas9	negative selection	11910526
64157313	64157336	3	-	28162770	MV411	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	0.7541557402829709	[220]	[313]	6	hSpCas9	negative selection	11910527
64157271	64157294	3	+	28162770	MV411	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	-1.4630558320222398	[35]	[10]	-7	hSpCas9	negative selection	11910528
64157211	64157234	3	-	28162770	MV411	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	-2.074490544104587	[54]	[10]	-8	hSpCas9	negative selection	11910529
64153215	64153238	3	+	28162770	MV411	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.0564947680713801	[362]	[317]	0	hSpCas9	negative selection	11910530
64147595	64147618	3	+	28162770	MV411	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	0.24743755078277535	[129]	[129]	2	hSpCas9	negative selection	11910531
64147305	64147328	3	-	28162770	MV411	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	0.3687438470049087	[341]	[371]	3	hSpCas9	negative selection	11910532
64157290	64157313	3	+	28162770	MONOMAC1	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	-0.07967989642139517	[58]	[63]	0	hSpCas9	negative selection	12079889
64147157	64147180	3	+	28162770	MONOMAC1	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	0.8492568052143813	[91]	[189]	7	hSpCas9	negative selection	12079890
64147062	64147085	3	-	28162770	MONOMAC1	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	0.3410590486236281	[145]	[211]	3	hSpCas9	negative selection	12079891
64159972	64159995	3	+	28162770	MONOMAC1	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	-0.7287573265037304	[265]	[183]	-5	hSpCas9	negative selection	12079892
64157313	64157336	3	-	28162770	MONOMAC1	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	1.6656611088418254	[178]	[650]	9	hSpCas9	negative selection	12079893
64157271	64157294	3	+	28162770	MONOMAC1	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	-0.518964941946916	[9]	[7]	-4	hSpCas9	negative selection	12079894
64157211	64157234	3	-	28162770	MONOMAC1	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	1.1534604000245796	[39]	[101]	8	hSpCas9	negative selection	12079895
64153215	64153238	3	+	28162770	MONOMAC1	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.6742298388182435	[245]	[449]	6	hSpCas9	negative selection	12079896
64147595	64147618	3	+	28162770	MONOMAC1	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	0.05671974518622924	[77]	[92]	0	hSpCas9	negative selection	12079897
64147305	64147328	3	-	28162770	MONOMAC1	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	-0.27907261592556526	[198]	[187]	-2	hSpCas9	negative selection	12079898
64157290	64157313	3	+	28162770	OCIAML2	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	-0.12823762779508363	[13]	[70]	-1	hSpCas9	negative selection	12249255
64147157	64147180	3	+	28162770	OCIAML2	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	0.4191872570074159	[33]	[251]	4	hSpCas9	negative selection	12249256
64147062	64147085	3	-	28162770	OCIAML2	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	0.8512982696452012	[37]	[379]	8	hSpCas9	negative selection	12249257
64159972	64159995	3	+	28162770	OCIAML2	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	-0.18264906227813668	[42]	[209]	-1	hSpCas9	negative selection	12249258
64157313	64157336	3	-	28162770	OCIAML2	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	0.7466008909785079	[39]	[371]	7	hSpCas9	negative selection	12249259
64157271	64157294	3	+	28162770	OCIAML2	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	-0.8076648125197319	[5]	[18]	-5	hSpCas9	negative selection	12249260
64157211	64157234	3	-	28162770	OCIAML2	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	0.6527525902631208	[6]	[60]	6	hSpCas9	negative selection	12249261
64153215	64153238	3	+	28162770	OCIAML2	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.8935048297658904	[63]	[658]	8	hSpCas9	negative selection	12249262
64147595	64147618	3	+	28162770	OCIAML2	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	-0.19761133083574534	[23]	[115]	-2	hSpCas9	negative selection	12249263
64147305	64147328	3	-	28162770	OCIAML2	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	-0.1677474860453455	[60]	[300]	-1	hSpCas9	negative selection	12249264
64157290	64157313	3	+	28162770	OCIAML3	viability	GCGGGTGCCAGCAAACGCCGTGG	PRICKLE2	ENSG00000163637	0.7650734529806651	[22]	[117]	7	hSpCas9	negative selection	12418621
64147157	64147180	3	+	28162770	OCIAML3	viability	GCTTGCCCCACATTTCGGGCTGG	PRICKLE2	ENSG00000163637	0.7026093660340117	[45]	[225]	6	hSpCas9	negative selection	12418622
64147062	64147085	3	-	28162770	OCIAML3	viability	GAGAAGACTATTACCCGGGGAGG	PRICKLE2	ENSG00000163637	-0.04726446183349717	[50]	[148]	0	hSpCas9	negative selection	12418623
64159972	64159995	3	+	28162770	OCIAML3	viability	GGAAAGGCCTGACATTCCCGCGG	PRICKLE2	ENSG00000163637	0.4677685572625264	[79]	[333]	4	hSpCas9	negative selection	12418624
64157313	64157336	3	-	28162770	OCIAML3	viability	GCTGTGTTTGCGTCACGCGCTGG	PRICKLE2	ENSG00000163637	0.9382133983250197	[64]	[375]	7	hSpCas9	negative selection	12418625
64157271	64157294	3	+	28162770	OCIAML3	viability	ACAGTGCATACGAAGCACGGCGG	PRICKLE2	ENSG00000163637	0.8389517669519431	[4]	[26]	7	hSpCas9	negative selection	12418626
64157211	64157234	3	-	28162770	OCIAML3	viability	CAAGATGGGAAGATATACTGTGG	PRICKLE2	ENSG00000163637	-1.2569726530465923	[18]	[23]	-7	hSpCas9	negative selection	12418627
64153215	64153238	3	+	28162770	OCIAML3	viability	CATACAAGGACTCGAAGCAGTGG	PRICKLE2	ENSG00000163637	0.035473527175637676	[116]	[361]	0	hSpCas9	negative selection	12418628
64147595	64147618	3	+	28162770	OCIAML3	viability	GGAGGAATGGCCGCCCCAGGAGG	PRICKLE2	ENSG00000163637	-0.25697265304659245	[37]	[95]	-2	hSpCas9	negative selection	12418629
64147305	64147328	3	-	28162770	OCIAML3	viability	TCAACCGGGACCCCATCTGGAGG	PRICKLE2	ENSG00000163637	-0.6418361654147783	[91]	[177]	-5	hSpCas9	negative selection	12418630