Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5571
• Symbol: PRKAG1
• Description: protein kinase AMP-activated non-catalytic subunit gamma 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PRKAG1

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
49003143	49003166	12	-	26472758	Jiyoye	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	0.30947870761874025	[167]	[156]	2	hSpCas9	negative selection	127323
49003882	49003905	12	+	26472758	Jiyoye	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	0.14414097567207973	[17]	[14]	1	hSpCas9	negative selection	127324
49003766	49003789	12	-	26472758	Jiyoye	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	-0.10301935081331076	[140]	[98]	0	hSpCas9	negative selection	127325
49003805	49003828	12	+	26472758	Jiyoye	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	-1.177787119215283	[26]	[8]	-7	hSpCas9	negative selection	127326
49005119	49005142	12	-	26472758	Jiyoye	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	7.326038618780467	[0]	[120]	9	hSpCas9	negative selection	127327
49004986	49005009	12	+	26472758	Jiyoye	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	1.9998735310066347	[61]	[186]	8	hSpCas9	negative selection	127328
49005305	49005328	12	+	26472758	Jiyoye	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.5088462258547738	[316]	[167]	-4	hSpCas9	negative selection	127329
49004970	49004993	12	+	26472758	Jiyoye	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	-0.3297902126603328	[299]	[179]	-2	hSpCas9	negative selection	127330
49004588	49004611	12	-	26472758	Jiyoye	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	1.354707961611738	[27]	[53]	7	hSpCas9	negative selection	127331
49004572	49004595	12	+	26472758	Jiyoye	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	-1.576336495705558	[86]	[21]	-7	hSpCas9	negative selection	127332
49003143	49003166	12	-	26472758	KBM7	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	0.6018609720613209	[798,560]	[640,333]	6	hSpCas9	negative selection	318441
49003882	49003905	12	+	26472758	KBM7	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	0.7402347655127884	[127,155]	[184,48]	7	hSpCas9	negative selection	318442
49003766	49003789	12	-	26472758	KBM7	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	0.039283235509410486	[453,386]	[192,210]	0	hSpCas9	negative selection	318443
49003805	49003828	12	+	26472758	KBM7	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	-1.1175683083978947	[186,187]	[24,54]	-7	hSpCas9	negative selection	318444
49005119	49005142	12	-	26472758	KBM7	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	0.3672355093580355	[322,218]	[200,126]	4	hSpCas9	negative selection	318445
49004986	49005009	12	+	26472758	KBM7	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	-0.26417700515547254	[842,393]	[378,104]	-3	hSpCas9	negative selection	318446
49005305	49005328	12	+	26472758	KBM7	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.7285658311389416	[642,832]	[729,455]	7	hSpCas9	negative selection	318447
49004970	49004993	12	+	26472758	KBM7	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	0.18718253689875686	[858,744]	[450,407]	2	hSpCas9	negative selection	318448
49004588	49004611	12	-	26472758	KBM7	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.534891632478865	[601,835]	[259,218]	-5	hSpCas9	negative selection	318449
49004572	49004595	12	+	26472758	KBM7	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	0.07887718531713878	[368,372]	[293,87]	0	hSpCas9	negative selection	318450
49003143	49003166	12	-	26472758	Raji	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	0.2372928579680329	[328]	[89]	2	hSpCas9	negative selection	509559
49003882	49003905	12	+	26472758	Raji	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	2.2416846270851907	[40]	[44]	9	hSpCas9	negative selection	509560
49003766	49003789	12	-	26472758	Raji	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	-0.3426493852614483	[152]	[27]	-3	hSpCas9	negative selection	509561
49003805	49003828	12	+	26472758	Raji	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	1.8178769181786145	[43]	[35]	9	hSpCas9	negative selection	509562
49005119	49005142	12	-	26472758	Raji	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	0.9880846070012551	[125]	[57]	8	hSpCas9	negative selection	509563
49004986	49005009	12	+	26472758	Raji	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.00729521096708996	[372]	[86]	0	hSpCas9	negative selection	509564
49005305	49005328	12	+	26472758	Raji	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.35718223473513455	[562]	[101]	-3	hSpCas9	negative selection	509565
49004970	49004993	12	+	26472758	Raji	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	0.6023893393558585	[385]	[135]	5	hSpCas9	negative selection	509566
49004588	49004611	12	-	26472758	Raji	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.14895621788618618	[386]	[80]	-1	hSpCas9	negative selection	509567
49004572	49004595	12	+	26472758	Raji	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	-1.040515159738714	[194]	[21]	-6	hSpCas9	negative selection	509568
49003143	49003166	12	-	26472758	K562	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	0.5503266019633368	[651]	[805]	4	hSpCas9	negative selection	700677
49003882	49003905	12	+	26472758	K562	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	-0.8898823640451443	[89]	[40]	-5	hSpCas9	negative selection	700678
49003766	49003789	12	-	26472758	K562	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	0.3607979113807756	[368]	[399]	3	hSpCas9	negative selection	700679
49003805	49003828	12	+	26472758	K562	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	-5.022367813028454	[76]	[1]	-9	hSpCas9	negative selection	700680
49005119	49005142	12	-	26472758	K562	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	1.0517736497240509	[339]	[594]	8	hSpCas9	negative selection	700681
49004986	49005009	12	+	26472758	K562	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.2319277834832501	[463]	[459]	1	hSpCas9	negative selection	700682
49005305	49005328	12	+	26472758	K562	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.1827721782202446	[764]	[732]	1	hSpCas9	negative selection	700683
49004970	49004993	12	+	26472758	K562	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	-0.17942466898773812	[985]	[734]	-1	hSpCas9	negative selection	700684
49004588	49004611	12	-	26472758	K562	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.23069659220763977	[473]	[340]	-1	hSpCas9	negative selection	700685
49004572	49004595	12	+	26472758	K562	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	-0.1725359746066878	[250]	[187]	-1	hSpCas9	negative selection	700686
49002988	49003011	12	+	26627737	DLD1	viability	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	0.5929680360406651	[987]	[426,649,346]	6	hSpCas9	negative selection	783926
49003159	49003182	12	-	26627737	DLD1	viability	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.9578352438196842	[560]	[320,280,406]	8	hSpCas9	negative selection	783927
49004945	49004968	12	+	26627737	DLD1	viability	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	0.843511403044023	[109]	[21,56,99]	7	hSpCas9	negative selection	783928
49005288	49005311	12	+	26627737	DLD1	viability	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	0.7562408349847699	[265]	[85,296,57]	7	hSpCas9	negative selection	783929
49005739	49005762	12	-	26627737	DLD1	viability	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	-0.8229046156664812	[30]	[7,0,6]	-7	hSpCas9	negative selection	783930
49018731	49018754	12	-	26627737	DLD1	viability	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.0021920949732421313	[134]	[31,35,55]	0	hSpCas9	negative selection	783931
49002988	49003011	12	+	26627737	GBM cells	viability after 5 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.3030565795990716	[642]	[269,288]	-5	hSpCas9	negative selection	866241
49003159	49003182	12	-	26627737	GBM cells	viability after 5 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.5570920609611368	[428]	[351,324]	7	hSpCas9	negative selection	866242
49004945	49004968	12	+	26627737	GBM cells	viability after 5 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	-0.030696797222916627	[119]	[69,55]	0	hSpCas9	negative selection	866243
49005288	49005311	12	+	26627737	GBM cells	viability after 5 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-0.9264075937013677	[201]	[77,35]	-8	hSpCas9	negative selection	866244
49005739	49005762	12	-	26627737	GBM cells	viability after 5 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	-0.36412053094810837	[5]	[3,0]	-5	hSpCas9	negative selection	866245
49018731	49018754	12	-	26627737	GBM cells	viability after 5 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.7829101650880594	[76]	[24,22]	-8	hSpCas9	negative selection	866246
49002988	49003011	12	+	26627737	GBM cells	viability after 13 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.11180558708862276	[642]	[393,264]	-1	hSpCas9	negative selection	948556
49003159	49003182	12	-	26627737	GBM cells	viability after 13 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.4361068169961043	[428]	[288,335]	5	hSpCas9	negative selection	948557
49004945	49004968	12	+	26627737	GBM cells	viability after 13 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	-0.3087245763689832	[119]	[83,26]	-4	hSpCas9	negative selection	948558
49005288	49005311	12	+	26627737	GBM cells	viability after 13 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-1.192914951305247	[201]	[69,29]	-8	hSpCas9	negative selection	948559
49005739	49005762	12	-	26627737	GBM cells	viability after 13 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	0.2971406228572908	[5]	[3,3]	4	hSpCas9	negative selection	948560
49018731	49018754	12	-	26627737	GBM cells	viability after 13 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.45116631946258146	[76]	[45,17]	-5	hSpCas9	negative selection	948561
49002988	49003011	12	+	26627737	GBM cells	viability after 21 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.3145858809774982	[642]	[306,256]	-3	hSpCas9	negative selection	1030871
49003159	49003182	12	-	26627737	GBM cells	viability after 21 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.7076154461719478	[428]	[412,350]	7	hSpCas9	negative selection	1030872
49004945	49004968	12	+	26627737	GBM cells	viability after 21 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	0.15788749472222863	[119]	[78,66]	1	hSpCas9	negative selection	1030873
49005288	49005311	12	+	26627737	GBM cells	viability after 21 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-1.0443225592298102	[201]	[59,46]	-7	hSpCas9	negative selection	1030874
49005739	49005762	12	-	26627737	GBM cells	viability after 21 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	-1.704729201105498	[5]	[0,0]	-8	hSpCas9	negative selection	1030875
49018731	49018754	12	-	26627737	GBM cells	viability after 21 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-1.9271216224419456	[76]	[10,10]	-8	hSpCas9	negative selection	1030876
49002988	49003011	12	+	26627737	RPE1	viability after 9 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.24998979573850288	[2106]	[276,912]	-2	hSpCas9	negative selection	1113186
49003159	49003182	12	-	26627737	RPE1	viability after 9 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.367507945212492	[1026]	[409,420]	2	hSpCas9	negative selection	1113187
49004945	49004968	12	+	26627737	RPE1	viability after 9 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	2.373118198727462	[12]	[0,46]	9	hSpCas9	negative selection	1113188
49005288	49005311	12	+	26627737	RPE1	viability after 9 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-1.7423489662761256	[734]	[49,92]	-8	hSpCas9	negative selection	1113189
49005739	49005762	12	-	26627737	RPE1	viability after 9 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	4.960327638446863	[3]	[0,87]	9	hSpCas9	negative selection	1113190
49018731	49018754	12	-	26627737	RPE1	viability after 9 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	1.3498744973734746	[66]	[35,75]	7	hSpCas9	negative selection	1113191
49002988	49003011	12	+	26627737	RPE1	viability after 12 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.4218117721027046	[2106]	[356,491]	-3	hSpCas9	negative selection	1195501
49003159	49003182	12	-	26627737	RPE1	viability after 12 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.3250888737592916	[1026]	[333,357]	2	hSpCas9	negative selection	1195502
49004945	49004968	12	+	26627737	RPE1	viability after 12 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	0.7458687760925251	[12]	[0,10]	5	hSpCas9	negative selection	1195503
49005288	49005311	12	+	26627737	RPE1	viability after 12 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-1.3427315304439045	[734]	[89,64]	-7	hSpCas9	negative selection	1195504
49005739	49005762	12	-	26627737	RPE1	viability after 12 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	0.46726811286926395	[3]	[0,1]	3	hSpCas9	negative selection	1195505
49018731	49018754	12	-	26627737	RPE1	viability after 12 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	0.7119664596936532	[66]	[28,29]	4	hSpCas9	negative selection	1195506
49002988	49003011	12	+	26627737	RPE1	viability after 15 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.407128297449189	[2106]	[478,420]	-3	hSpCas9	negative selection	1277816
49003159	49003182	12	-	26627737	RPE1	viability after 15 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.4405574438919108	[1026]	[547,245]	3	hSpCas9	negative selection	1277817
49004945	49004968	12	+	26627737	RPE1	viability after 15 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	3.0042841007363497	[12]	[0,56]	9	hSpCas9	negative selection	1277818
49005288	49005311	12	+	26627737	RPE1	viability after 15 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-1.8350211670742838	[734]	[98,18]	-8	hSpCas9	negative selection	1277819
49005739	49005762	12	-	26627737	RPE1	viability after 15 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	2.42830900909078	[3]	[0,10]	9	hSpCas9	negative selection	1277820
49018731	49018754	12	-	26627737	RPE1	viability after 15 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	1.5148926558535551	[66]	[44,62]	7	hSpCas9	negative selection	1277821
49002988	49003011	12	+	26627737	RPE1	viability after 18 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.505929625159654	[2106]	[266,542]	-3	hSpCas9	negative selection	1360131
49003159	49003182	12	-	26627737	RPE1	viability after 18 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.7475783149645145	[1026]	[547,376]	4	hSpCas9	negative selection	1360132
49004945	49004968	12	+	26627737	RPE1	viability after 18 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	2.5352275390008505	[12]	[0,40]	9	hSpCas9	negative selection	1360133
49005288	49005311	12	+	26627737	RPE1	viability after 18 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-2.048965305202885	[734]	[45,49]	-8	hSpCas9	negative selection	1360134
49005739	49005762	12	-	26627737	RPE1	viability after 18 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	3.373140215642761	[3]	[1,20]	9	hSpCas9	negative selection	1360135
49018731	49018754	12	-	26627737	RPE1	viability after 18 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	1.0394858074523743	[66]	[41,31]	6	hSpCas9	negative selection	1360136
49002988	49003011	12	+	26627737	HeLa	viability after 8 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	0.24379119331034804	[811]	[455,382,423]	2	hSpCas9	negative selection	1442446
49003159	49003182	12	-	26627737	HeLa	viability after 8 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.36166832240656754	[819]	[702,382,350]	3	hSpCas9	negative selection	1442447
49004945	49004968	12	+	26627737	HeLa	viability after 8 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	3.2376262147663617	[21]	[159,76,51]	9	hSpCas9	negative selection	1442448
49005288	49005311	12	+	26627737	HeLa	viability after 8 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	0.37225778292877604	[264]	[202,142,115]	3	hSpCas9	negative selection	1442449
49005739	49005762	12	-	26627737	HeLa	viability after 8 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	-2.023442785508129	[39]	[1,0,8]	-9	hSpCas9	negative selection	1442450
49018731	49018754	12	-	26627737	HeLa	viability after 8 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-1.0577908603261028	[172]	[42,30,35]	-8	hSpCas9	negative selection	1442451
49002988	49003011	12	+	26627737	HeLa	viability after 12 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	0.5072243677662187	[811]	[494,489,444]	4	hSpCas9	negative selection	1524761
49003159	49003182	12	-	26627737	HeLa	viability after 12 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.15269083780789594	[819]	[313,322,496]	1	hSpCas9	negative selection	1524762
49004945	49004968	12	+	26627737	HeLa	viability after 12 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	2.941165952547405	[21]	[166,34,13]	9	hSpCas9	negative selection	1524763
49005288	49005311	12	+	26627737	HeLa	viability after 12 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-1.13730540013731	[264]	[34,67,43]	-8	hSpCas9	negative selection	1524764
49005739	49005762	12	-	26627737	HeLa	viability after 12 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	-1.141984629619273	[39]	[1,0,19]	-8	hSpCas9	negative selection	1524765
49018731	49018754	12	-	26627737	HeLa	viability after 12 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.09749141617870194	[172]	[151,37,15]	-1	hSpCas9	negative selection	1524766
49002988	49003011	12	+	26627737	HeLa	viability after 15 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	0.036792348918727624	[811]	[241,383,396]	0	hSpCas9	negative selection	1607076
49003159	49003182	12	-	26627737	HeLa	viability after 15 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.4656427873312152	[819]	[381,407,604]	4	hSpCas9	negative selection	1607077
49004945	49004968	12	+	26627737	HeLa	viability after 15 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	0.7368831003697918	[21]	[15,10,17]	6	hSpCas9	negative selection	1607078
49005288	49005311	12	+	26627737	HeLa	viability after 15 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-0.6322986967067212	[264]	[45,130,28]	-5	hSpCas9	negative selection	1607079
49005739	49005762	12	-	26627737	HeLa	viability after 15 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	-1.7760011086784173	[39]	[2,9,0]	-9	hSpCas9	negative selection	1607080
49018731	49018754	12	-	26627737	HeLa	viability after 15 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-1.593352473626639	[172]	[21,0,48]	-8	hSpCas9	negative selection	1607081
49002988	49003011	12	+	26627737	HeLa	viability after 18 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	0.028581053683596647	[811]	[164,309,396]	0	hSpCas9	negative selection	1689391
49003159	49003182	12	-	26627737	HeLa	viability after 18 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.4788121951190356	[819]	[249,355,604]	4	hSpCas9	negative selection	1689392
49004945	49004968	12	+	26627737	HeLa	viability after 18 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	0.7750278549599385	[21]	[9,10,17]	6	hSpCas9	negative selection	1689393
49005288	49005311	12	+	26627737	HeLa	viability after 18 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-0.6607267932326728	[264]	[26,109,28]	-5	hSpCas9	negative selection	1689394
49005739	49005762	12	-	26627737	HeLa	viability after 18 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	-1.5507483791419014	[39]	[2,8,0]	-8	hSpCas9	negative selection	1689395
49018731	49018754	12	-	26627737	HeLa	viability after 18 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-1.613309716906277	[172]	[13,0,48]	-8	hSpCas9	negative selection	1689396
49002988	49003011	12	+	26627737	HCT116	viability after 6 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	0.6582880038622005	[1332]	[516,227]	3	hSpCas9	negative selection	1771706
49003159	49003182	12	-	26627737	HCT116	viability after 6 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.27930372400056624	[1388]	[235,280]	1	hSpCas9	negative selection	1771707
49004945	49004968	12	+	26627737	HCT116	viability after 6 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	1.0958949375315201	[100]	[2,50]	6	hSpCas9	negative selection	1771708
49005288	49005311	12	+	26627737	HCT116	viability after 6 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	1.3841446393901542	[737]	[802,26]	7	hSpCas9	negative selection	1771709
49005739	49005762	12	-	26627737	HCT116	viability after 6 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	1.0842977564664116	[2]	[0,0]	6	hSpCas9	negative selection	1771710
49018731	49018754	12	-	26627737	HCT116	viability after 6 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-1.9363617140996814	[32]	[1,0]	-8	hSpCas9	negative selection	1771711
49002988	49003011	12	+	26627737	HCT116	viability after 8 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.1710815397626222	[748]	[396,398,304]	-2	hSpCas9	negative selection	1854021
49003159	49003182	12	-	26627737	HCT116	viability after 8 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.7107322517170959	[466]	[388,461,411]	6	hSpCas9	negative selection	1854022
49004945	49004968	12	+	26627737	HCT116	viability after 8 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	0.6356579896141572	[57]	[38,78,30]	6	hSpCas9	negative selection	1854023
49005288	49005311	12	+	26627737	HCT116	viability after 8 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-0.9663936056587614	[357]	[107,93,100]	-8	hSpCas9	negative selection	1854024
49005739	49005762	12	-	26627737	HCT116	viability after 8 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	3.083849898717676	[0]	[3,4,4]	9	hSpCas9	negative selection	1854025
49018731	49018754	12	-	26627737	HCT116	viability after 8 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.14160262726001727	[104]	[40,51,63]	-1	hSpCas9	negative selection	1854026
49002988	49003011	12	+	26627737	HCT116	viability after 9 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.08071890203969057	[1332]	[416,272]	0	hSpCas9	negative selection	1936336
49003159	49003182	12	-	26627737	HCT116	viability after 9 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.3857934294988634	[1388]	[683,326]	3	hSpCas9	negative selection	1936337
49004945	49004968	12	+	26627737	HCT116	viability after 9 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	0.633825343521583	[100]	[28,51]	4	hSpCas9	negative selection	1936338
49005288	49005311	12	+	26627737	HCT116	viability after 9 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-1.156865639950432	[737]	[79,94]	-7	hSpCas9	negative selection	1936339
49005739	49005762	12	-	26627737	HCT116	viability after 9 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	2.187389542054194	[2]	[6,0]	9	hSpCas9	negative selection	1936340
49018731	49018754	12	-	26627737	HCT116	viability after 9 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.1557430448197321	[32]	[3,10]	-1	hSpCas9	negative selection	1936341
49002988	49003011	12	+	26627737	HCT116	viability after 12 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.19848775952102105	[748]	[485,197,328]	-2	hSpCas9	negative selection	2018651
49003159	49003182	12	-	26627737	HCT116	viability after 12 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.5402545203688908	[466]	[288,370,416]	5	hSpCas9	negative selection	2018652
49004945	49004968	12	+	26627737	HCT116	viability after 12 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	0.5349619361787743	[57]	[32,65,34]	5	hSpCas9	negative selection	2018653
49005288	49005311	12	+	26627737	HCT116	viability after 12 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-0.5269496788436538	[357]	[113,205,74]	-5	hSpCas9	negative selection	2018654
49005739	49005762	12	-	26627737	HCT116	viability after 12 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	4.645095936842278	[0]	[5,9,23]	9	hSpCas9	negative selection	2018655
49018731	49018754	12	-	26627737	HCT116	viability after 12 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.8417169342363351	[104]	[21,24,45]	-7	hSpCas9	negative selection	2018656
49002988	49003011	12	+	26627737	HCT116	viability after 15 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	0.19995925962524974	[748]	[469,485,522]	2	hSpCas9	negative selection	2100966
49003159	49003182	12	-	26627737	HCT116	viability after 15 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.23633489477441072	[466]	[420,257,281]	2	hSpCas9	negative selection	2100967
49004945	49004968	12	+	26627737	HCT116	viability after 15 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	-0.5647656467325466	[57]	[23,42,0]	-5	hSpCas9	negative selection	2100968
49005288	49005311	12	+	26627737	HCT116	viability after 15 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-0.22625880950946547	[357]	[122,234,162]	-2	hSpCas9	negative selection	2100969
49005739	49005762	12	-	26627737	HCT116	viability after 15 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	5.403782960718277	[0]	[30,38,3]	9	hSpCas9	negative selection	2100970
49018731	49018754	12	-	26627737	HCT116	viability after 15 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.024614045457189482	[104]	[85,27,66]	0	hSpCas9	negative selection	2100971
49002988	49003011	12	+	26627737	HCT116	viability after 18 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.1516313570119725	[748]	[408,239,334]	-1	hSpCas9	negative selection	2183281
49003159	49003182	12	-	26627737	HCT116	viability after 18 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.6553105066904296	[466]	[444,290,333]	5	hSpCas9	negative selection	2183282
49004945	49004968	12	+	26627737	HCT116	viability after 18 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	-0.28125835208466166	[57]	[6,22,39]	-3	hSpCas9	negative selection	2183283
49005288	49005311	12	+	26627737	HCT116	viability after 18 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-0.49087087821835984	[357]	[158,103,106]	-4	hSpCas9	negative selection	2183284
49005739	49005762	12	-	26627737	HCT116	viability after 18 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	4.975142141038023	[0]	[20,0,24]	9	hSpCas9	negative selection	2183285
49018731	49018754	12	-	26627737	HCT116	viability after 18 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.7216665125946762	[104]	[24,18,49]	-6	hSpCas9	negative selection	2183286
49005124	49005147	12	-	24336569	HL60	viability	AAGAACACAAGATAGAAACTTGG	PRKAG1	ENSG00000181929	-1.1217815558163846	[761]	[740]	-7	hSpCas9	negative selection	2286352
49005305	49005328	12	-	24336569	HL60	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	1.3353403248241356	[152]	[816]	8	hSpCas9	negative selection	2286353
49005311	49005334	12	+	24336569	HL60	viability	CTGATTTATAGTAGCGGTGCAGG	PRKAG1	ENSG00000181929	-0.19431744031879275	[617]	[1142]	-2	hSpCas9	negative selection	2286354
49005333	49005356	12	+	24336569	HL60	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.5055462287411188	[703]	[2114]	4	hSpCas9	negative selection	2286355
49005473	49005496	12	+	24336569	HL60	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	-0.15828842143288824	[645]	[1224]	-1	hSpCas9	negative selection	2286356
49005728	49005751	12	+	24336569	HL60	viability	GAGGATTTCACCCACCTGCAGGG	PRKAG1	ENSG00000181929	0.1491681602389157	[423]	[994]	1	hSpCas9	negative selection	2286357
49005739	49005762	12	-	24336569	HL60	viability	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	1.036145704083852	[155]	[676]	7	hSpCas9	negative selection	2286358
49005752	49005775	12	+	24336569	HL60	viability	CGTATCAAATACAACCAATTTGG	PRKAG1	ENSG00000181929	0.7802246709956735	[401]	[1460]	6	hSpCas9	negative selection	2286359
49005761	49005784	12	+	24336569	HL60	viability	TACAACCAATTTGGAGCTTGTGG	PRKAG1	ENSG00000181929	0.4739851198492461	[213]	[628]	4	hSpCas9	negative selection	2286360
49005766	49005789	12	-	24336569	HL60	viability	GATTCCCACAAGCTCCAAATTGG	PRKAG1	ENSG00000181929	0.04553020850273293	[738]	[1613]	0	hSpCas9	negative selection	2286361
49005124	49005147	12	-	24336569	KBM7	viability	AAGAACACAAGATAGAAACTTGG	PRKAG1	ENSG00000181929	0.45860575216814625	[408]	[1532]	4	hSpCas9	negative selection	2353529
49005305	49005328	12	-	24336569	KBM7	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-0.7664013805684231	[231]	[371]	-5	hSpCas9	negative selection	2353530
49005311	49005334	12	+	24336569	KBM7	viability	CTGATTTATAGTAGCGGTGCAGG	PRKAG1	ENSG00000181929	0.6244536041318509	[375]	[1580]	5	hSpCas9	negative selection	2353531
49005333	49005356	12	+	24336569	KBM7	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.4946680358021184	[394]	[1517]	4	hSpCas9	negative selection	2353532
49005473	49005496	12	+	24336569	KBM7	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.6017766442823241	[430]	[1783]	5	hSpCas9	negative selection	2353533
49005728	49005751	12	+	24336569	KBM7	viability	GAGGATTTCACCCACCTGCAGGG	PRKAG1	ENSG00000181929	-0.8754123011328143	[301]	[448]	-6	hSpCas9	negative selection	2353534
49005739	49005762	12	-	24336569	KBM7	viability	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	0.3331077750466416	[233]	[803]	3	hSpCas9	negative selection	2353535
49005752	49005775	12	+	24336569	KBM7	viability	CGTATCAAATACAACCAATTTGG	PRKAG1	ENSG00000181929	0.8546156797959892	[529]	[2613]	7	hSpCas9	negative selection	2353536
49005761	49005784	12	+	24336569	KBM7	viability	TACAACCAATTTGGAGCTTGTGG	PRKAG1	ENSG00000181929	0.31013767510526064	[282]	[956]	3	hSpCas9	negative selection	2353537
49005766	49005789	12	-	24336569	KBM7	viability	GATTCCCACAAGCTCCAAATTGG	PRKAG1	ENSG00000181929	-0.00631015569685911	[653]	[1775]	0	hSpCas9	negative selection	2353538
49018864	49018887	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCAAGGAACCCACCCTTCCGG	PRKAG1	ENSG00000181929	-0.6916335158508313	[445,766]	[59,106]	-4	dCas9-VP64	positive selection	2412291
49018831	49018854	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTGGCGACTGCCATGACGTGGG	PRKAG1	ENSG00000181929	-0.7754599709125729	[87,302]	[19,29]	-4	dCas9-VP64	positive selection	2412292
49018883	49018906	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTACCGAGGCCCGCCACCGCCGG	PRKAG1	ENSG00000181929	1.5019230920102062	[292,418]	[320,116]	5	dCas9-VP64	positive selection	2412293
49007883	49007906	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTTGCTCTGTCACCCAGG	PRKAG1	ENSG00000181929	0.18377208399179143	[26,157]	[32,11]	0	dCas9-VP64	positive selection	2421978
49018922	49018945	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCGGATCCGTGCGGTCCGCGAGG	PRKAG1	ENSG00000181929	-0.8032452400642077	[355,104]	[43,11]	-4	dCas9-VP64	positive selection	2431012
49018907	49018930	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCCTCCCCCGGGTCCTCGCGG	PRKAG1	ENSG00000181929	-2.260647927050619	[242,52]	[8,3]	-9	dCas9-VP64	positive selection	2431013
49018942	49018965	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGCTGACGGCGAGGGTCATGGG	PRKAG1	ENSG00000181929	0.244707112500252	[42,17]	[13,0]	1	dCas9-VP64	positive selection	2431014
49015983	49016006	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCATTCAGGCTGGAGTGCAGCGG	PRKAG1	ENSG00000181929	0.7741136303930765	[29,7]	[9,2]	3	dCas9-VP64	positive selection	2455168
49018864	49018887	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCAAGGAACCCACCCTTCCGG	PRKAG1	ENSG00000181929	-0.8275513802597728	[157,318]	[29,55]	-7	dCas9-VP64	positive selection	2507546
49018831	49018854	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTGGCGACTGCCATGACGTGGG	PRKAG1	ENSG00000181929	0.29442342227781104	[139,268]	[121,42]	2	dCas9-VP64	positive selection	2507547
49018883	49018906	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTACCGAGGCCCGCCACCGCCGG	PRKAG1	ENSG00000181929	0.21507675625920064	[191,301]	[98,87]	1	dCas9-VP64	positive selection	2507548
49007883	49007906	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTTGCTCTGTCACCCAGG	PRKAG1	ENSG00000181929	1.2364773942763427	[105,126]	[117,63]	7	dCas9-VP64	positive selection	2517233
49018922	49018945	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCGGATCCGTGCGGTCCGCGAGG	PRKAG1	ENSG00000181929	4.046339867004273	[96,19]	[654,13]	9	dCas9-VP64	positive selection	2526267
49018907	49018930	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCCTCCCCCGGGTCCTCGCGG	PRKAG1	ENSG00000181929	-0.16107256824349628	[178,90]	[56,21]	-1	dCas9-VP64	positive selection	2526268
49018942	49018965	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGCTGACGGCGAGGGTCATGGG	PRKAG1	ENSG00000181929	-0.3970231919921539	[67,96]	[24,15]	-4	dCas9-VP64	positive selection	2526269
49015983	49016006	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCATTCAGGCTGGAGTGCAGCGG	PRKAG1	ENSG00000181929	0.6857223168869587	[164,83]	[44,84]	5	dCas9-VP64	positive selection	2550423
49005306	49005329	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.2544017577528124	[4,3]	[3,1]	-4	hSpCas9	positive selection	3013631
49005476	49005499	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCTTACTATCCCATAAAGGGG	PRKAG1	ENSG00000181929	0.08392420011747351	[4,4]	[3,3]	1	hSpCas9	positive selection	3013632
49005798	49005821	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCGATGAGACTTCATGAAGG	PRKAG1	ENSG00000181929	0.22616913848249737	[4,4]	[4,4]	5	hSpCas9	positive selection	3013633
49004971	49004994	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	-0.7774929611293376	[3,3]	[2,0]	-8	hSpCas9	positive selection	3013634
49005306	49005329	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.3670728714092152	[4,4]	[3,0]	-5	hSpCas9	positive selection	3081489
49005476	49005499	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCTTACTATCCCATAAAGGGG	PRKAG1	ENSG00000181929	0.4758478708242798	[4,4]	[4,3]	7	hSpCas9	positive selection	3081490
49005798	49005821	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCGATGAGACTTCATGAAGG	PRKAG1	ENSG00000181929	-0.13810700718220362	[4,4]	[3,1]	-2	hSpCas9	positive selection	3081491
49004971	49004994	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	-0.6577471574309717	[3,3]	[2,0]	-8	hSpCas9	positive selection	3081492
49005305	49005328		-	24336571	A375	resistance to PLX after 7 days	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.06925331941533042	[6,6]	[7,5]	2	hSpCas9	positive selection	3137750
49013067	49013090		+	24336571	A375	resistance to PLX after 7 days	GGATGCTCATTTTCCACAGCTGG	PRKAG1	ENSG00000181929	-0.06572862057895026	[15,13]	[9,17]	-2	hSpCas9	positive selection	3137751
49005487	49005510		-	24336571	A375	resistance to PLX after 7 days	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	-0.3275879039938747	[43,47]	[35,36]	-8	hSpCas9	positive selection	3137752
49013080	49013103		-	24336571	A375	resistance to PLX after 7 days	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	0.19347543335679587	[9,11]	[10,14]	6	hSpCas9	positive selection	3137753
49005305	49005328		-	24336571	A375	resistance to PLX after 14 days	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.5315705732589451	[6,5]	[3,4]	5	hSpCas9	positive selection	3195543
49013067	49013090		+	24336571	A375	resistance to PLX after 14 days	GGATGCTCATTTTCCACAGCTGG	PRKAG1	ENSG00000181929	-0.37800611530883416	[11,17]	[4,4]	-4	hSpCas9	positive selection	3195544
49005487	49005510		-	24336571	A375	resistance to PLX after 14 days	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	-0.5433444456728997	[41,51]	[13,15]	-6	hSpCas9	positive selection	3195545
49013080	49013103		-	24336571	A375	resistance to PLX after 14 days	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	0.7303721273480913	[7,10]	[6,6]	6	hSpCas9	positive selection	3195546
49005305	49005328		-	24336571	A375	viability after 7 days	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-0.836540739970026	[12]	[6,6]	-8	hSpCas9	negative selection	3253336
49013067	49013090		+	24336571	A375	viability after 7 days	GGATGCTCATTTTCCACAGCTGG	PRKAG1	ENSG00000181929	0.11987897868778453	[13]	[15,13]	1	hSpCas9	negative selection	3253337
49005487	49005510		-	24336571	A375	viability after 7 days	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.5754063536464191	[31]	[43,47]	8	hSpCas9	negative selection	3253338
49013080	49013103		-	24336571	A375	viability after 7 days	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.44158176895501655	[15]	[9,11]	-6	hSpCas9	negative selection	3253339
49005305	49005328		-	24336571	A375	viability after 14 days	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-0.8628420216015155	[12]	[6,5]	-8	hSpCas9	negative selection	3311129
49013067	49013090		+	24336571	A375	viability after 14 days	GGATGCTCATTTTCCACAGCTGG	PRKAG1	ENSG00000181929	0.17075034420945567	[13]	[11,17]	2	hSpCas9	negative selection	3311130
49005487	49005510		-	24336571	A375	viability after 14 days	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.6338253976748642	[31]	[41,51]	7	hSpCas9	negative selection	3311131
49013080	49013103		-	24336571	A375	viability after 14 days	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.6802720944690015	[15]	[7,10]	-7	hSpCas9	negative selection	3311132
49005473	49005496	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	1.2573262114458352	[447,447]	[6,6]	5	hSpCas9	positive selection	3387458
49013080	49013103	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	0.5708256842626168	[102,102]	[0,0]	3	hSpCas9	positive selection	3387459
49005333	49005356	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.28956824844180157	[186,186]	[0,0]	-2	hSpCas9	positive selection	3387460
49005305	49005328	12	+	26780180	HT29	viability (Avana library 4 designs)	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.559670707437304	[]	[]	2	hSpCas9	negative selection	3451816
49005475	49005498	12	+	26780180	HT29	viability (Avana library 4 designs)	CTTCTTACTATCCCATAAAGGGG	PRKAG1	ENSG00000181929	0.986546060757837	[]	[]	4	hSpCas9	negative selection	3451817
49005797	49005820	12	+	26780180	HT29	viability (Avana library 4 designs)	GCAGCGATGAGACTTCATGAAGG	PRKAG1	ENSG00000181929	0.280553496770541	[]	[]	1	hSpCas9	negative selection	3451818
49004970	49004993	12	+	26780180	HT29	viability (Avana library 4 designs)	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	1.30869343466487	[]	[]	5	hSpCas9	negative selection	3451819
49004970	49004993	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	0.498577370715995	[]	[]	0	hSpCas9	negative selection	3547894
49005797	49005820	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCGATGAGACTTCATGAAGG	PRKAG1	ENSG00000181929	1.3928607077732	[]	[]	2	hSpCas9	negative selection	3547895
49005305	49005328	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.610697081938349	[]	[]	0	hSpCas9	negative selection	3547896
49005475	49005498	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCTTACTATCCCATAAAGGGG	PRKAG1	ENSG00000181929	-18.9706764701602	[]	[]	-9	hSpCas9	negative selection	3547897
49005728	49005751	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGGATTTCACCCACCTGCAGGG	PRKAG1	ENSG00000181929	1.44890160135898	[]	[]	2	hSpCas9	negative selection	3547898
49005305	49005328	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-7.91335763027953	[]	[]	-7	hSpCas9	negative selection	3547899
49004970	49004993	12	+	26780180	A375	viability (Avana lentiGuide)	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	-4.37257861166478	[]	[]	-7	hSpCas9	negative selection	3656553
49005797	49005820	12	+	26780180	A375	viability (Avana lentiGuide)	GCAGCGATGAGACTTCATGAAGG	PRKAG1	ENSG00000181929	12.1241815742551	[]	[]	7	hSpCas9	negative selection	3656554
49005305	49005328	12	+	26780180	A375	viability (Avana lentiGuide)	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	4.47372037029901	[]	[]	4	hSpCas9	negative selection	3656555
49005475	49005498	12	+	26780180	A375	viability (Avana lentiGuide)	CTTCTTACTATCCCATAAAGGGG	PRKAG1	ENSG00000181929	5.37881922757114	[]	[]	5	hSpCas9	negative selection	3656556
49005728	49005751	12	+	26780180	A375	viability (Avana lentiGuide)	GAGGATTTCACCCACCTGCAGGG	PRKAG1	ENSG00000181929	-0.248832583983318	[]	[]	0	hSpCas9	negative selection	3656557
49005305	49005328	12	-	26780180	A375	viability (Avana lentiGuide)	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-3.21730662728728	[]	[]	-5	hSpCas9	negative selection	3656558
49004970	49004993	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	-0.11249681267677134	[6]	[5,5]	-2	hSpCas9	positive selection	3765160
49005797	49005820	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCGATGAGACTTCATGAAGG	PRKAG1	ENSG00000181929	-0.24074174518020933	[5]	[5,3]	-4	hSpCas9	positive selection	3765161
49005305	49005328	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.07017907813520866	[4]	[5,3]	-1	hSpCas9	positive selection	3765162
49005475	49005498	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCTTACTATCCCATAAAGGGG	PRKAG1	ENSG00000181929	-1.2489193734907031	[7]	[2,1]	-9	hSpCas9	positive selection	3765163
49005728	49005751	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGGATTTCACCCACCTGCAGGG	PRKAG1	ENSG00000181929	0.08697956174976476	[4]	[5,4]	2	hSpCas9	positive selection	3765164
49005305	49005328	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-0.4116354210090389	[4]	[3,3]	-6	hSpCas9	positive selection	3765165
49004970	49004993	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	-0.13178401786214122	[4]	[2,4]	-2	hSpCas9	positive selection	3873767
49005797	49005820	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCGATGAGACTTCATGAAGG	PRKAG1	ENSG00000181929	-0.6731454468848381	[6]	[3,2]	-7	hSpCas9	positive selection	3873768
49005305	49005328	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.10478078942904334	[5]	[4,2]	-1	hSpCas9	positive selection	3873769
49005475	49005498	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCTTACTATCCCATAAAGGGG	PRKAG1	ENSG00000181929	-0.33817329940004726	[5]	[3,3]	-4	hSpCas9	positive selection	3873770
49005728	49005751	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGGATTTCACCCACCTGCAGGG	PRKAG1	ENSG00000181929	-0.3381356699944753	[5]	[3,3]	-4	hSpCas9	positive selection	3873771
49005305	49005328	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.28783723109482484	[5]	[6,5]	7	hSpCas9	positive selection	3873772
49005305	49005328	12	+	26780180	A375	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.788703160307782	[]	[]	3	hSpCas9	negative selection	3984219
49005305	49005328	12	-	26780180	A375	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	1.01364025561526	[]	[]	5	hSpCas9	negative selection	3984220
49005333	49005356	12	+	26780180	A375	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	1.25292512865642	[]	[]	6	hSpCas9	negative selection	3984221
49005487	49005510	12	-	26780180	A375	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.498097365316369	[]	[]	1	hSpCas9	negative selection	3984222
49005473	49005496	12	+	26780180	A375	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	-0.204666011136279	[]	[]	-6	hSpCas9	negative selection	3984223
49013080	49013103	12	-	26780180	A375	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	1.45172246233821	[]	[]	8	hSpCas9	negative selection	3984224
49005305	49005328	12	+	26780180	HT29	viability (GeCKOv2 library)	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.622278248869129	[]	[]	2	hSpCas9	negative selection	4092185
49005305	49005328	12	-	26780180	HT29	viability (GeCKOv2 library)	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.614287156096031	[]	[]	2	hSpCas9	negative selection	4092186
49005333	49005356	12	+	26780180	HT29	viability (GeCKOv2 library)	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	1.23218125423733	[]	[]	6	hSpCas9	negative selection	4092187
49005487	49005510	12	-	26780180	HT29	viability (GeCKOv2 library)	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.140836199639173	[]	[]	0	hSpCas9	negative selection	4092188
49005473	49005496	12	+	26780180	HT29	viability (GeCKOv2 library)	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	-0.0549600127563096	[]	[]	-2	hSpCas9	negative selection	4092189
49013080	49013103	12	-	26780180	HT29	viability (GeCKOv2 library)	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	1.25663548795896	[]	[]	6	hSpCas9	negative selection	4092190
49005305	49005328	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.4889146672037532	[1]	[1,1]	9	hSpCas9	positive selection	4162905
49013067	49013090	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGATGCTCATTTTCCACAGCTGG	PRKAG1	ENSG00000181929	0.16786615900349397	[3]	[2,2]	4	hSpCas9	positive selection	4162906
49005487	49005510	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.14674643528986409	[5]	[3,3]	4	hSpCas9	positive selection	4162907
49013080	49013103	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.10014661269042943	[4]	[1,2]	-2	hSpCas9	positive selection	4162908
49005305	49005328	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-0.4459619923700869	[3]	[0,0,1,0]	-6	hSpCas9	positive selection	4226927
49013067	49013090	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGATGCTCATTTTCCACAGCTGG	PRKAG1	ENSG00000181929	0.5769491012837673	[2]	[3,3,1,0]	4	hSpCas9	positive selection	4226928
49005487	49005510	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.30008747324728957	[4]	[4,3,1,0]	2	hSpCas9	positive selection	4226929
49013080	49013103	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	0.3553582224539995	[3]	[5,2,0,0]	2	hSpCas9	positive selection	4226930
49005487	49005510	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.38142552729183254	[2]	[3,1]	7	hSpCas9	positive selection	4292147
49005305	49005328	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-0.0710058881721885	[3]	[3,2]	-1	hSpCas9	positive selection	4292148
49005305	49005328	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.09564559593425742	[2]	[2,1]	2	hSpCas9	positive selection	4292149
49005473	49005496	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.20063438400054212	[3]	[4,2]	4	hSpCas9	positive selection	4356405
49013080	49013103	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.34563086132259707	[2]	[1,0]	-6	hSpCas9	positive selection	4356406
49005333	49005356	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.11807613875282007	[2]	[2,2]	2	hSpCas9	positive selection	4356407
49004562	49004584	12	-	27760321	OCIAML3	viability	CAGTTATTGACCCAGAATCAGG	PRKAG1	ENSG00000181929	-1.7551163454338936	[375,307]	[67,92]	-8	hSpCas9	negative selection	4430561
49004588	49004610	12	-	27760321	OCIAML3	viability	AATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.14558981862772624	[220,213]	[147,161]	-1	hSpCas9	negative selection	4430562
49004987	49005009	12	+	27760321	OCIAML3	viability	AAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	-0.7151033983779795	[282,229]	[121,120]	-6	hSpCas9	negative selection	4430563
49005306	49005328	12	+	27760321	OCIAML3	viability	CAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.7712855615541594	[12,10]	[18,11]	8	hSpCas9	negative selection	4430564
49005474	49005496	12	+	27760321	OCIAML3	viability	GCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	1.6908954668611944	[38,34]	[101,81]	9	hSpCas9	negative selection	4430565
49004562	49004584	12	-	27760321	OCIAML2	viability	CAGTTATTGACCCAGAATCAGG	PRKAG1	ENSG00000181929	0.25566977564739657	[375,307]	[247,434]	3	hSpCas9	negative selection	4514024
49004588	49004610	12	-	27760321	OCIAML2	viability	AATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.35388587816654415	[220,213]	[124,154]	-4	hSpCas9	negative selection	4514025
49004987	49005009	12	+	27760321	OCIAML2	viability	AAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.08274434428503341	[282,229]	[171,279]	1	hSpCas9	negative selection	4514026
49005306	49005328	12	+	27760321	OCIAML2	viability	CAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-1.4951135068135164	[12,10]	[2,3]	-8	hSpCas9	negative selection	4514027
49005474	49005496	12	+	27760321	OCIAML2	viability	GCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	-0.09950496223282634	[38,34]	[20,36]	-1	hSpCas9	negative selection	4514028
49004562	49004584	12	-	27760321	MV411	viability	CAGTTATTGACCCAGAATCAGG	PRKAG1	ENSG00000181929	-0.027892163201548137	[375,307]	[81,427]	0	hSpCas9	negative selection	4597487
49004588	49004610	12	-	27760321	MV411	viability	AATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	0.9433598920568754	[220,213]	[212,371]	7	hSpCas9	negative selection	4597488
49004987	49005009	12	+	27760321	MV411	viability	AAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.3076354421687995	[282,229]	[215,196]	2	hSpCas9	negative selection	4597489
49005306	49005328	12	+	27760321	MV411	viability	CAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.39855189664002477	[12,10]	[11,7]	3	hSpCas9	negative selection	4597490
49005474	49005496	12	+	27760321	MV411	viability	GCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	-0.9538601590334572	[38,34]	[0,29]	-6	hSpCas9	negative selection	4597491
49004562	49004584	12	-	27760321	HL60	viability	CAGTTATTGACCCAGAATCAGG	PRKAG1	ENSG00000181929	-0.41614489200885685	[375,307]	[252,160]	-5	hSpCas9	negative selection	4680950
49004588	49004610	12	-	27760321	HL60	viability	AATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-1.814636185891625	[220,213]	[20,81]	-9	hSpCas9	negative selection	4680951
49004987	49005009	12	+	27760321	HL60	viability	AAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	4.113144100339239	[282,229]	[3428,3795]	9	hSpCas9	negative selection	4680952
49005306	49005328	12	+	27760321	HL60	viability	CAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-3.288013917369235	[12,10]	[0,0]	-9	hSpCas9	negative selection	4680953
49005474	49005496	12	+	27760321	HL60	viability	GCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.24148281227628443	[38,34]	[41,28]	3	hSpCas9	negative selection	4680954
49004562	49004584	12	-	27760321	HT1080	viability	CAGTTATTGACCCAGAATCAGG	PRKAG1	ENSG00000181929	1.288656752071388	[307,240]	[344,181]	7	hSpCas9	negative selection	4764413
49004588	49004610	12	-	27760321	HT1080	viability	AATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-3.872537863660535	[213,166]	[8,0]	-8	hSpCas9	negative selection	4764414
49004987	49005009	12	+	27760321	HT1080	viability	AAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	-0.40453850016337456	[229,179]	[44,79]	-2	hSpCas9	negative selection	4764415
49005306	49005328	12	+	27760321	HT1080	viability	CAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-1.9983308370974173	[10,8]	[0,0]	-6	hSpCas9	negative selection	4764416
49005474	49005496	12	+	27760321	HT1080	viability	GCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	-0.5410365315675278	[34,27]	[0,16]	-2	hSpCas9	negative selection	4764417
49004562	49004584	12	-	27760321	HT29	viability after 7 days	CAGTTATTGACCCAGAATCAGG	PRKAG1	ENSG00000181929	0.036861663384142096	[307,240]	[191,361,502]	0	hSpCas9	negative selection	4847876
49004588	49004610	12	-	27760321	HT29	viability after 7 days	AATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.7517578625447271	[213,166]	[239,170,41]	-8	hSpCas9	negative selection	4847877
49004987	49005009	12	+	27760321	HT29	viability after 7 days	AAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	-0.7104511814710386	[229,179]	[231,125,135]	-7	hSpCas9	negative selection	4847878
49005306	49005328	12	+	27760321	HT29	viability after 7 days	CAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-3.3131522894203957	[10,8]	[1,0,0]	-9	hSpCas9	negative selection	4847879
49005474	49005496	12	+	27760321	HT29	viability after 7 days	GCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.0516816265913298	[34,27]	[89,3,38]	0	hSpCas9	negative selection	4847880
49004562	49004584	12	-	27760321	HT29	viability after 25 days	CAGTTATTGACCCAGAATCAGG	PRKAG1	ENSG00000181929	0.041553009373799354	[307,240]	[268,488,200]	0	hSpCas9	negative selection	4931339
49004588	49004610	12	-	27760321	HT29	viability after 25 days	AATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	0.13164004322391076	[213,166]	[227,376,95]	1	hSpCas9	negative selection	4931340
49004987	49005009	12	+	27760321	HT29	viability after 25 days	AAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	-0.28082317738622065	[229,179]	[198,107,279]	-3	hSpCas9	negative selection	4931341
49005306	49005328	12	+	27760321	HT29	viability after 25 days	CAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-3.075213807311311	[10,8]	[1,0,0]	-8	hSpCas9	negative selection	4931342
49005474	49005496	12	+	27760321	HT29	viability after 25 days	GCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	-2.538109516132619	[34,27]	[1,0,16]	-8	hSpCas9	negative selection	4931343
49004562	49004584	12	-	27760321	HT29	viability after 22 days	CAGTTATTGACCCAGAATCAGG	PRKAG1	ENSG00000181929	-0.8159888988770834	[307,240]	[194,210,133]	-6	hSpCas9	negative selection	5014802
49004588	49004610	12	-	27760321	HT29	viability after 22 days	AATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.2578340162605538	[213,166]	[204,160,185]	-3	hSpCas9	negative selection	5014803
49004987	49005009	12	+	27760321	HT29	viability after 22 days	AAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	-0.3979700939152033	[229,179]	[218,97,221]	-4	hSpCas9	negative selection	5014804
49005306	49005328	12	+	27760321	HT29	viability after 22 days	CAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-2.2956856923138957	[10,8]	[4,0,0]	-8	hSpCas9	negative selection	5014805
49005474	49005496	12	+	27760321	HT29	viability after 22 days	GCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	-1.4679924523066665	[34,27]	[29,5,2]	-7	hSpCas9	negative selection	5014806
49004562	49004584	12	-	27760321	HT29	viability after 19 days	CAGTTATTGACCCAGAATCAGG	PRKAG1	ENSG00000181929	-0.730510517692734	[307,240]	[328,218,39]	-5	hSpCas9	negative selection	5098265
49004588	49004610	12	-	27760321	HT29	viability after 19 days	AATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-1.1981142109678538	[213,166]	[137,47,102]	-7	hSpCas9	negative selection	5098266
49004987	49005009	12	+	27760321	HT29	viability after 19 days	AAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	-0.33825457092708344	[229,179]	[238,192,131]	-3	hSpCas9	negative selection	5098267
49005306	49005328	12	+	27760321	HT29	viability after 19 days	CAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-3.5194916813799875	[10,8]	[0,0,0]	-9	hSpCas9	negative selection	5098268
49005474	49005496	12	+	27760321	HT29	viability after 19 days	GCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.0240258683173864	[34,27]	[103,0,12]	0	hSpCas9	negative selection	5098269
49004562	49004584	12	-	27760321	HT29	viability after 16 days	CAGTTATTGACCCAGAATCAGG	PRKAG1	ENSG00000181929	0.24059198715822017	[307,240]	[284,488,303]	2	hSpCas9	negative selection	5181728
49004588	49004610	12	-	27760321	HT29	viability after 16 days	AATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.7830703750742972	[213,166]	[155,107,110]	-6	hSpCas9	negative selection	5181729
49004987	49005009	12	+	27760321	HT29	viability after 16 days	AAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.0035995002137053644	[229,179]	[263,232,195]	0	hSpCas9	negative selection	5181730
49005306	49005328	12	+	27760321	HT29	viability after 16 days	CAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-1.701395126127058	[10,8]	[0,7,0]	-8	hSpCas9	negative selection	5181731
49005474	49005496	12	+	27760321	HT29	viability after 16 days	GCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	-0.04764967716862589	[34,27]	[61,36,5]	0	hSpCas9	negative selection	5181732
49004562	49004584	12	-	27760321	HT29	viability after 13 days	CAGTTATTGACCCAGAATCAGG	PRKAG1	ENSG00000181929	-0.1377886721309896	[307,240]	[280,443,151]	-2	hSpCas9	negative selection	5265191
49004588	49004610	12	-	27760321	HT29	viability after 13 days	AATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.7010214331413517	[213,166]	[132,124,148]	-6	hSpCas9	negative selection	5265192
49004987	49005009	12	+	27760321	HT29	viability after 13 days	AAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.0045859489554735955	[229,179]	[308,156,248]	0	hSpCas9	negative selection	5265193
49005306	49005328	12	+	27760321	HT29	viability after 13 days	CAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.2951679152039146	[10,8]	[0,29,11]	4	hSpCas9	negative selection	5265194
49005474	49005496	12	+	27760321	HT29	viability after 13 days	GCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	-1.6547880321667092	[34,27]	[24,0,8]	-8	hSpCas9	negative selection	5265195
49004562	49004584	12	-	27760321	HT29	viability after 10 days	CAGTTATTGACCCAGAATCAGG	PRKAG1	ENSG00000181929	0.17342061164797465	[307,240]	[524,351,283]	2	hSpCas9	negative selection	5348654
49004588	49004610	12	-	27760321	HT29	viability after 10 days	AATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.7099657716270188	[213,166]	[126,229,82]	-7	hSpCas9	negative selection	5348655
49004987	49005009	12	+	27760321	HT29	viability after 10 days	AAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	-0.6258033862302206	[229,179]	[199,96,197]	-6	hSpCas9	negative selection	5348656
49005306	49005328	12	+	27760321	HT29	viability after 10 days	CAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-2.9083261766635182	[10,8]	[2,0,0]	-9	hSpCas9	negative selection	5348657
49005474	49005496	12	+	27760321	HT29	viability after 10 days	GCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.022098106431883036	[34,27]	[91,16,10]	0	hSpCas9	negative selection	5348658
49004562	49004584	12	-	27760321	MOLM13	viability	CAGTTATTGACCCAGAATCAGG	PRKAG1	ENSG00000181929	-1.2340630850794243	[375,307]	[52,105]	-6	hSpCas9	negative selection	5432117
49004588	49004610	12	-	27760321	MOLM13	viability	AATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-1.929526117660977	[220,213]	[41,23]	-8	hSpCas9	negative selection	5432118
49004987	49005009	12	+	27760321	MOLM13	viability	AAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.11552365049090185	[282,229]	[337,0]	0	hSpCas9	negative selection	5432119
49005306	49005328	12	+	27760321	MOLM13	viability	CAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	3.4747703736045503	[12,10]	[0,137]	9	hSpCas9	negative selection	5432120
49005474	49005496	12	+	27760321	MOLM13	viability	GCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.3894758130669742	[38,34]	[49,7]	2	hSpCas9	negative selection	5432121
49018299	49018322	12	+	27661255	K562	viability	GGATCACAGAAAGACCATCGAGG	PRKAG1	ENSG00000181929	0.1310955503806326	[766,908]	[766,699]	4	dCas9-KRAB	negative selection	5504122
49018321	49018344	12	+	27661255	K562	viability	GTCCAGGAGCTACCTGCAAGCGG	PRKAG1	ENSG00000181929	0.3746881735037924	[513,751]	[709,600]	9	dCas9-KRAB	negative selection	5504123
49018704	49018727	12	-	27661255	K562	viability	GAGTGCAGGAGGGCGGTCGGGGG	PRKAG1	ENSG00000181929	0.049642952603761725	[408,526]	[436,340]	1	dCas9-KRAB	negative selection	5504124
49018731	49018754	12	-	27661255	K562	viability	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	0.4271649294996109	[724,945]	[999,801]	9	dCas9-KRAB	negative selection	5504125
49005487	49005510	12	-	27260156	BXPC3	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.2941953208678336	[267]	[246,330,442,366]	6	hSpCas9	negative selection	5564607
49005305	49005328	12	-	27260156	BXPC3	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.036550451831730446	[893]	[939,916,981,998]	0	hSpCas9	negative selection	5564608
49005305	49005328	12	+	27260156	BXPC3	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.3554302549237678	[221]	[265,255,348,324]	7	hSpCas9	negative selection	5564609
49005473	49005496	12	+	27260156	BXPC3	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.3248821796217425	[733]	[854,952,1013,1038]	7	hSpCas9	negative selection	5628865
49013080	49013103	12	-	27260156	BXPC3	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.1810310941962021	[251]	[158,300,231,240]	-4	hSpCas9	negative selection	5628866
49005333	49005356	12	+	27260156	BXPC3	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.004100854441765875	[430]	[252,485,585,496]	0	hSpCas9	negative selection	5628867
49005487	49005510	12	-	27260156	A673	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.3588038226314568	[267]	[502,335,355,470]	8	hSpCas9	negative selection	5685858
49005305	49005328	12	-	27260156	A673	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.04188085508898409	[893]	[1024,1194,1076,1109]	1	hSpCas9	negative selection	5685859
49005305	49005328	12	+	27260156	A673	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.018019023981522553	[221]	[261,256,352,201]	0	hSpCas9	negative selection	5685860
49005473	49005496	12	+	27260156	A673	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.4814622503270267	[733]	[1383,1163,1139,1252]	9	hSpCas9	negative selection	5750116
49013080	49013103	12	-	27260156	A673	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	0.3507142100151833	[251]	[473,335,392,348]	7	hSpCas9	negative selection	5750117
49005333	49005356	12	+	27260156	A673	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.14449434614857068	[430]	[601,479,597,614]	3	hSpCas9	negative selection	5750118
49005487	49005510	12	-	27260156	A375	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.6380428919499861	[267]	[443,627,490,411]	8	hSpCas9	negative selection	5807109
49005305	49005328	12	-	27260156	A375	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-0.22503597268098818	[893]	[872,905,948,848]	-3	hSpCas9	negative selection	5807110
49005305	49005328	12	+	27260156	A375	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.20737606828283495	[221]	[146,327,153,275]	-3	hSpCas9	negative selection	5807111
49005473	49005496	12	+	27260156	A375	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.7678558634934622	[733]	[1664,1374,1331,1451]	9	hSpCas9	negative selection	5871367
49013080	49013103	12	-	27260156	A375	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.5017979386988474	[251]	[254,196,275,112]	-6	hSpCas9	negative selection	5871368
49005333	49005356	12	+	27260156	A375	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.11646425968001245	[430]	[475,720,686,344]	1	hSpCas9	negative selection	5871369
49005487	49005510	12	-	27260156	COLO741	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.3602455114063095	[267]	[421,576,325]	7	hSpCas9	negative selection	5928360
49005305	49005328	12	-	27260156	COLO741	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-0.10985397926238882	[893]	[1127,1271,798]	-2	hSpCas9	negative selection	5928361
49005305	49005328	12	+	27260156	COLO741	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.05483054238891838	[221]	[371,323,140]	-1	hSpCas9	negative selection	5928362
49005473	49005496	12	+	27260156	COLO741	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.23627562809609237	[733]	[1204,1121,1000]	5	hSpCas9	negative selection	5992618
49013080	49013103	12	-	27260156	COLO741	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.17262983959921563	[251]	[378,239,247]	-4	hSpCas9	negative selection	5992619
49005333	49005356	12	+	27260156	COLO741	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.1779580355666829	[430]	[642,641,586]	4	hSpCas9	negative selection	5992620
49005487	49005510	12	-	27260156	CAL120	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.5119879529046978	[267]	[612,403,430]	7	hSpCas9	negative selection	6049611
49005305	49005328	12	-	27260156	CAL120	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.037827424269953	[893]	[1143,975,1302]	0	hSpCas9	negative selection	6049612
49005305	49005328	12	+	27260156	CAL120	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.03695961190017938	[221]	[504,171,167]	0	hSpCas9	negative selection	6049613
49005473	49005496	12	+	27260156	CAL120	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.5075928684710289	[733]	[925,1222,1682]	7	hSpCas9	negative selection	6113869
49013080	49013103	12	-	27260156	CAL120	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-1.287360950906155	[251]	[152,103,131]	-9	hSpCas9	negative selection	6113870
49005333	49005356	12	+	27260156	CAL120	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.24872272142638718	[430]	[322,409,598]	-4	hSpCas9	negative selection	6113871
49005487	49005510	12	-	27260156	CADOES1	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.4085888177318592	[267]	[293,404,234,391]	6	hSpCas9	negative selection	6170862
49005305	49005328	12	-	27260156	CADOES1	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.38876025924696156	[893]	[1027,794,1287,1248]	6	hSpCas9	negative selection	6170863
49005305	49005328	12	+	27260156	CADOES1	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.03502902523462503	[221]	[241,132,173,258]	0	hSpCas9	negative selection	6170864
49005473	49005496	12	+	27260156	CADOES1	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.5127607788118531	[733]	[926,919,998,1052]	8	hSpCas9	negative selection	6235120
49013080	49013103	12	-	27260156	CADOES1	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	0.193589629921878	[251]	[253,379,231,203]	3	hSpCas9	negative selection	6235121
49005333	49005356	12	+	27260156	CADOES1	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.6498576422371095	[430]	[714,502,624,673]	9	hSpCas9	negative selection	6235122
49005487	49005510	12	-	27260156	EWS502	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.5252255537355823	[267]	[283,456,478,427]	8	hSpCas9	negative selection	6292113
49005305	49005328	12	-	27260156	EWS502	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.20879654318493646	[893]	[904,1003,1000,1518]	3	hSpCas9	negative selection	6292114
49005305	49005328	12	+	27260156	EWS502	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.21909666222596114	[221]	[129,224,207,255]	-4	hSpCas9	negative selection	6292115
49005473	49005496	12	+	27260156	EWS502	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.42692155078766647	[733]	[1192,626,1368,986]	7	hSpCas9	negative selection	6356371
49013080	49013103	12	-	27260156	EWS502	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	0.06273231469577945	[251]	[160,446,150,366]	1	hSpCas9	negative selection	6356372
49005333	49005356	12	+	27260156	EWS502	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.08003112600153843	[430]	[415,359,474,483]	-1	hSpCas9	negative selection	6356373
49005487	49005510	12	-	27260156	EW8	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.475619872636634	[267]	[351,263,268,332]	8	hSpCas9	negative selection	6413364
49005305	49005328	12	-	27260156	EW8	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.05662948330593376	[893]	[793,772,702,754]	1	hSpCas9	negative selection	6413365
49005305	49005328	12	+	27260156	EW8	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.3436752874994784	[221]	[190,135,118,129]	-6	hSpCas9	negative selection	6413366
49005473	49005496	12	+	27260156	EW8	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.34769546322775235	[733]	[843,722,643,842]	6	hSpCas9	negative selection	6477622
49013080	49013103	12	-	27260156	EW8	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.042067842760793006	[251]	[179,241,198,169]	-1	hSpCas9	negative selection	6477623
49005333	49005356	12	+	27260156	EW8	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.09550550907518215	[430]	[457,205,336,504]	1	hSpCas9	negative selection	6477624
49005487	49005510	12	-	27260156	CORL105	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.6330707458555862	[267]	[629,360,532,436]	9	hSpCas9	negative selection	6534615
49005305	49005328	12	-	27260156	CORL105	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.15414449496091776	[893]	[1217,910,1520,1070]	3	hSpCas9	negative selection	6534616
49005305	49005328	12	+	27260156	CORL105	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.48503470772084245	[221]	[300,348,396,410]	8	hSpCas9	negative selection	6534617
49005473	49005496	12	+	27260156	CORL105	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.45104233074119016	[733]	[1344,958,1348,1082]	8	hSpCas9	negative selection	6598873
49013080	49013103	12	-	27260156	CORL105	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.19375206298168202	[251]	[233,225,268,303]	-4	hSpCas9	negative selection	6598874
49005333	49005356	12	+	27260156	CORL105	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.0008495130375306276	[430]	[415,571,663,385]	0	hSpCas9	negative selection	6598875
49005487	49005510	12	-	27260156	HS294T	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.8950089453195401	[267]	[188,116,234,239]	9	hSpCas9	negative selection	6655866
49005305	49005328	12	-	27260156	HS294T	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.19930755496924435	[893]	[376,443,360,405]	2	hSpCas9	negative selection	6655867
49005305	49005328	12	+	27260156	HS294T	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.016046147436102	[221]	[69,110,57,103]	0	hSpCas9	negative selection	6655868
49005473	49005496	12	+	27260156	HS294T	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.6366879325505104	[733]	[326,525,350,592]	8	hSpCas9	negative selection	6720124
49013080	49013103	12	-	27260156	HS294T	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.4042244437286999	[251]	[58,46,59,141]	-5	hSpCas9	negative selection	6720125
49005333	49005356	12	+	27260156	HS294T	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.32494095824186714	[430]	[171,105,131,115]	-4	hSpCas9	negative selection	6720126
49005487	49005510	12	-	27260156	HCC44	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.5079390403289767	[267]	[333,530,644,230]	8	hSpCas9	negative selection	6777117
49005305	49005328	12	-	27260156	HCC44	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.088760309760198	[893]	[900,870,1300,1264]	1	hSpCas9	negative selection	6777118
49005305	49005328	12	+	27260156	HCC44	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.224592557944702	[221]	[298,248,360,280]	3	hSpCas9	negative selection	6777119
49005473	49005496	12	+	27260156	HCC44	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.5525341536371267	[733]	[1314,782,1592,1301]	8	hSpCas9	negative selection	6841375
49013080	49013103	12	-	27260156	HCC44	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.5583412078582952	[251]	[209,235,227,102]	-7	hSpCas9	negative selection	6841376
49005333	49005356	12	+	27260156	HCC44	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.015216207345970637	[430]	[514,482,354,550]	0	hSpCas9	negative selection	6841377
49005487	49005510	12	-	27260156	G402	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	1.1444924671987644	[267]	[580,932,1075,310]	9	hSpCas9	negative selection	6898368
49005305	49005328	12	-	27260156	G402	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-0.02154761409296968	[893]	[616,1677,733,1226]	0	hSpCas9	negative selection	6898369
49005305	49005328	12	+	27260156	G402	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.21677484854381635	[221]	[166,268,169,313]	-3	hSpCas9	negative selection	6898370
49005473	49005496	12	+	27260156	G402	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.7014983188441506	[733]	[1628,1681,1170,1379]	8	hSpCas9	negative selection	6962626
49013080	49013103	12	-	27260156	G402	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	0.015607407916974791	[251]	[431,403,307,129]	0	hSpCas9	negative selection	6962627
49005333	49005356	12	+	27260156	G402	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.2872132985074557	[430]	[1177,507,577,382]	3	hSpCas9	negative selection	6962628
49005487	49005510	12	-	27260156	L33	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.4807187255021299	[267]	[446,140,219,352]	8	hSpCas9	negative selection	7019619
49005305	49005328	12	-	27260156	L33	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.2789467278848191	[893]	[917,457,698,1193]	6	hSpCas9	negative selection	7019620
49005305	49005328	12	+	27260156	L33	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.6430826734102727	[221]	[360,165,189,317]	9	hSpCas9	negative selection	7019621
49005473	49005496	12	+	27260156	L33	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	-0.057554337272532896	[733]	[820,274,377,723]	-1	hSpCas9	negative selection	7083877
49013080	49013103	12	-	27260156	L33	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.15609955629755534	[251]	[221,90,128,254]	-4	hSpCas9	negative selection	7083878
49005333	49005356	12	+	27260156	L33	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.2235896398200169	[430]	[428,135,226,352]	-5	hSpCas9	negative selection	7083879
49005487	49005510	12	-	27260156	K562	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.40338620731275476	[267]	[347,255,313,335]	5	hSpCas9	negative selection	7140870
49005305	49005328	12	-	27260156	K562	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.21644299690577695	[893]	[787,784,886,1174]	2	hSpCas9	negative selection	7140871
49005305	49005328	12	+	27260156	K562	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.6299648701295766	[221]	[431,243,400,164]	7	hSpCas9	negative selection	7140872
49005473	49005496	12	+	27260156	K562	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.6919869752485952	[733]	[1009,1171,826,1182]	8	hSpCas9	negative selection	7205128
49013080	49013103	12	-	27260156	K562	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-1.1688571226566238	[251]	[216,107,15,69]	-8	hSpCas9	negative selection	7205129
49005333	49005356	12	+	27260156	K562	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.033453214837175435	[430]	[390,397,295,406]	0	hSpCas9	negative selection	7205130
49005487	49005510	12	-	27260156	HT29	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.2761855058459006	[267]	[388,462,417,319]	5	hSpCas9	negative selection	7262121
49005305	49005328	12	-	27260156	HT29	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.1953745739157512	[893]	[1301,1362,1378,972]	4	hSpCas9	negative selection	7262122
49005305	49005328	12	+	27260156	HT29	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.05637349861233942	[221]	[263,240,430,190]	1	hSpCas9	negative selection	7262123
49005473	49005496	12	+	27260156	HT29	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.4650215736875829	[733]	[1112,1561,1256,1029]	8	hSpCas9	negative selection	7326379
49013080	49013103	12	-	27260156	HT29	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.07144506194499323	[251]	[293,309,343,225]	-1	hSpCas9	negative selection	7326380
49005333	49005356	12	+	27260156	HT29	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.050520515047234316	[430]	[593,509,434,618]	1	hSpCas9	negative selection	7326381
49005487	49005510	12	-	27260156	MHHES1	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.5353048144760553	[267]	[561,474,447,304]	8	hSpCas9	negative selection	7383372
49005305	49005328	12	-	27260156	MHHES1	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.27624371217160626	[893]	[1269,1543,1162,969]	5	hSpCas9	negative selection	7383373
49005305	49005328	12	+	27260156	MHHES1	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.12074771061099998	[221]	[351,320,200,230]	2	hSpCas9	negative selection	7383374
49005473	49005496	12	+	27260156	MHHES1	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.415749390206799	[733]	[1297,1238,1232,739]	7	hSpCas9	negative selection	7447630
49013080	49013103	12	-	27260156	MHHES1	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.3815322551887106	[251]	[242,142,272,205]	-6	hSpCas9	negative selection	7447631
49005333	49005356	12	+	27260156	MHHES1	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.234536225750397	[430]	[492,502,388,300]	-4	hSpCas9	negative selection	7447632
49005487	49005510	12	-	27260156	MEWO	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	-0.08980170331186932	[267]	[240,192,273]	-2	hSpCas9	negative selection	7504623
49005305	49005328	12	-	27260156	MEWO	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.18837793057400753	[893]	[1204,903,798]	4	hSpCas9	negative selection	7504624
49005305	49005328	12	+	27260156	MEWO	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.1695915299876245	[221]	[162,131,254]	-4	hSpCas9	negative selection	7504625
49005473	49005496	12	+	27260156	MEWO	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.17334270301808796	[733]	[982,643,736]	4	hSpCas9	negative selection	7568881
49013080	49013103	12	-	27260156	MEWO	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.05104696163875355	[251]	[270,239,179]	-1	hSpCas9	negative selection	7568882
49005333	49005356	12	+	27260156	MEWO	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.08437955716733705	[430]	[450,426,408]	1	hSpCas9	negative selection	7568883
49005487	49005510	12	-	27260156	LNCAPCLONEFGC	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.37657319228907105	[267]	[271,345,292,344]	6	hSpCas9	negative selection	7625874
49005305	49005328	12	-	27260156	LNCAPCLONEFGC	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-0.090578167951882	[893]	[765,559,1111,668]	-1	hSpCas9	negative selection	7625875
49005305	49005328	12	+	27260156	LNCAPCLONEFGC	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.20278621965429333	[221]	[116,129,188,268]	-3	hSpCas9	negative selection	7625876
49005473	49005496	12	+	27260156	LNCAPCLONEFGC	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.598903686809549	[733]	[927,958,1342,851]	8	hSpCas9	negative selection	7690132
49013080	49013103	12	-	27260156	LNCAPCLONEFGC	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.39664374589342555	[251]	[59,218,188,226]	-6	hSpCas9	negative selection	7690133
49005333	49005356	12	+	27260156	LNCAPCLONEFGC	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.2882670482963636	[430]	[625,354,665,292]	4	hSpCas9	negative selection	7690134
49005487	49005510	12	-	27260156	PANC0327	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.5195377766347479	[267]	[163,277,576,339]	7	hSpCas9	negative selection	7747125
49005305	49005328	12	-	27260156	PANC0327	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.259789933504076	[893]	[819,793,1213,984]	4	hSpCas9	negative selection	7747126
49005305	49005328	12	+	27260156	PANC0327	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.3680287663676949	[221]	[125,236,92,141]	-5	hSpCas9	negative selection	7747127
49005473	49005496	12	+	27260156	PANC0327	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.7651170157856029	[733]	[1694,796,1312,715]	9	hSpCas9	negative selection	7811383
49013080	49013103	12	-	27260156	PANC0327	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	0.47583971315941914	[251]	[445,216,558,46]	7	hSpCas9	negative selection	7811384
49005333	49005356	12	+	27260156	PANC0327	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.26218111388194487	[430]	[364,380,560,531]	4	hSpCas9	negative selection	7811385
49005487	49005510	12	-	27260156	NCIH2009	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.8279776281938152	[267]	[816,723,480]	9	hSpCas9	negative selection	7868376
49005305	49005328	12	-	27260156	NCIH2009	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.13767446302730846	[893]	[1738,1162,1293]	2	hSpCas9	negative selection	7868377
49005305	49005328	12	+	27260156	NCIH2009	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.16328253280520966	[221]	[390,239,420]	2	hSpCas9	negative selection	7868378
49005473	49005496	12	+	27260156	NCIH2009	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.5310310938054084	[733]	[1451,1099,1891]	7	hSpCas9	negative selection	7932634
49013080	49013103	12	-	27260156	NCIH2009	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.9315599723914851	[251]	[214,210,132]	-8	hSpCas9	negative selection	7932635
49005333	49005356	12	+	27260156	NCIH2009	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.6597268493220072	[430]	[355,485,293]	-7	hSpCas9	negative selection	7932636
49005487	49005510	12	-	27260156	NCIH1373	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	1.0394180369391763	[267]	[745,578,539,164]	9	hSpCas9	negative selection	7989627
49005305	49005328	12	-	27260156	NCIH1373	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.2648260765870297	[893]	[1371,1133,1023,347]	2	hSpCas9	negative selection	7989628
49005305	49005328	12	+	27260156	NCIH1373	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.7174158041108563	[221]	[88,122,147,63]	-6	hSpCas9	negative selection	7989629
49005473	49005496	12	+	27260156	NCIH1373	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.7732177124721054	[733]	[1486,1475,1337,345]	7	hSpCas9	negative selection	8053885
49013080	49013103	12	-	27260156	NCIH1373	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-1.1979851211118893	[251]	[50,63,187,48]	-8	hSpCas9	negative selection	8053886
49005333	49005356	12	+	27260156	NCIH1373	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.4609946463099167	[430]	[422,255,340,106]	-4	hSpCas9	negative selection	8053887
49005487	49005510	12	-	27260156	PATU8902	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.8311686355074315	[267]	[937,604,451,712]	8	hSpCas9	negative selection	8110878
49005305	49005328	12	-	27260156	PATU8902	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-0.18588547397845823	[893]	[987,971,1264,1101]	-2	hSpCas9	negative selection	8110879
49005305	49005328	12	+	27260156	PATU8902	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.7344154549171442	[221]	[173,384,76,127]	-6	hSpCas9	negative selection	8110880
49005473	49005496	12	+	27260156	PATU8902	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.82380626807469	[733]	[2782,1592,1066,1979]	8	hSpCas9	negative selection	8175136
49013080	49013103	12	-	27260156	PATU8902	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-1.1275427721707396	[251]	[144,339,87,77]	-7	hSpCas9	negative selection	8175137
49005333	49005356	12	+	27260156	PATU8902	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.9356925674414662	[430]	[226,516,226,304]	-7	hSpCas9	negative selection	8175138
49005487	49005510	12	-	27260156	PANC1	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.7413424944011918	[267]	[388,783,199,260]	9	hSpCas9	negative selection	8232129
49005305	49005328	12	-	27260156	PANC1	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.3351623238791074	[893]	[799,1139,1018,942]	5	hSpCas9	negative selection	8232130
49005305	49005328	12	+	27260156	PANC1	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.6767991775027052	[221]	[408,469,226,162]	9	hSpCas9	negative selection	8232131
49005473	49005496	12	+	27260156	PANC1	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.6355236116862786	[733]	[1074,1115,958,805]	8	hSpCas9	negative selection	8296387
49013080	49013103	12	-	27260156	PANC1	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	0.08329668301453863	[251]	[205,185,419,113]	1	hSpCas9	negative selection	8296388
49005333	49005356	12	+	27260156	PANC1	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.08232987924080032	[430]	[423,467,190,476]	1	hSpCas9	negative selection	8296389
49005487	49005510	12	-	27260156	PANC0813	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.9233731865563808	[267]	[620,606,611,551]	9	hSpCas9	negative selection	8353380
49005305	49005328	12	-	27260156	PANC0813	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.36757226672399346	[893]	[1397,1426,1539,1072]	6	hSpCas9	negative selection	8353381
49005305	49005328	12	+	27260156	PANC0813	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.5627386147717706	[221]	[411,480,316,334]	8	hSpCas9	negative selection	8353382
49005473	49005496	12	+	27260156	PANC0813	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.40715985142462907	[733]	[937,970,1634,1017]	6	hSpCas9	negative selection	8417638
49013080	49013103	12	-	27260156	PANC0813	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.03925082665048607	[251]	[389,354,257,164]	0	hSpCas9	negative selection	8417639
49005333	49005356	12	+	27260156	PANC0813	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.11181388399723306	[430]	[575,381,555,374]	-2	hSpCas9	negative selection	8417640
49005487	49005510	12	-	27260156	RDES	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.6603348607882306	[267]	[436,391,525,619]	9	hSpCas9	negative selection	8474631
49005305	49005328	12	-	27260156	RDES	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.19055884015366742	[893]	[900,1287,1113,1440]	3	hSpCas9	negative selection	8474632
49005305	49005328	12	+	27260156	RDES	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.07144111423866994	[221]	[158,189,299,359]	-1	hSpCas9	negative selection	8474633
49005473	49005496	12	+	27260156	RDES	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.7039207445862363	[733]	[1078,1306,1497,1699]	9	hSpCas9	negative selection	8538889
49013080	49013103	12	-	27260156	RDES	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.5853104240273781	[251]	[141,161,293,185]	-7	hSpCas9	negative selection	8538890
49005333	49005356	12	+	27260156	RDES	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.038898337922955925	[430]	[447,527,628,416]	0	hSpCas9	negative selection	8538891
49005487	49005510	12	-	27260156	PC3	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.5504705231597931	[267]	[303,382,545,383]	9	hSpCas9	negative selection	8595882
49005305	49005328	12	-	27260156	PC3	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.022401391487874234	[893]	[623,899,1362,939]	0	hSpCas9	negative selection	8595883
49005305	49005328	12	+	27260156	PC3	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.567885774470754	[221]	[284,286,498,283]	9	hSpCas9	negative selection	8595884
49005473	49005496	12	+	27260156	PC3	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.5695249497631565	[733]	[839,1143,1287,1125]	9	hSpCas9	negative selection	8660140
49013080	49013103	12	-	27260156	PC3	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.4918135245704989	[251]	[94,129,298,265]	-8	hSpCas9	negative selection	8660141
49005333	49005356	12	+	27260156	PC3	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.1032093658287519	[430]	[277,392,595,681]	2	hSpCas9	negative selection	8660142
49005487	49005510	12	-	27260156	PATU8988T	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.8511014990023191	[267]	[379,430,501,558]	9	hSpCas9	negative selection	8717133
49005305	49005328	12	-	27260156	PATU8988T	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	-0.006072641249996069	[893]	[1057,790,982,577]	0	hSpCas9	negative selection	8717134
49005305	49005328	12	+	27260156	PATU8988T	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.134187909527969	[221]	[253,243,285,150]	2	hSpCas9	negative selection	8717135
49005473	49005496	12	+	27260156	PATU8988T	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.3745636921846558	[733]	[845,957,761,1134]	6	hSpCas9	negative selection	8781391
49013080	49013103	12	-	27260156	PATU8988T	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.3663115586684782	[251]	[224,200,145,184]	-6	hSpCas9	negative selection	8781392
49005333	49005356	12	+	27260156	PATU8988T	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.40188701401626475	[430]	[555,680,406,572]	6	hSpCas9	negative selection	8781393
49005487	49005510	12	-	27260156	T47D	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.4559842120022425	[267]	[418,403,492,396]	8	hSpCas9	negative selection	8838384
49005305	49005328	12	-	27260156	T47D	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.00298478775917288	[893]	[1071,882,1067,1168]	0	hSpCas9	negative selection	8838385
49005305	49005328	12	+	27260156	T47D	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.0948677677116605	[221]	[263,226,197,282]	-2	hSpCas9	negative selection	8838386
49005473	49005496	12	+	27260156	T47D	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.5250779405133201	[733]	[1282,1176,1222,1243]	9	hSpCas9	negative selection	8902642
49013080	49013103	12	-	27260156	T47D	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.43685731737884304	[251]	[250,166,167,288]	-7	hSpCas9	negative selection	8902643
49005333	49005356	12	+	27260156	T47D	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.15619081601444015	[430]	[660,580,545,444]	3	hSpCas9	negative selection	8902644
49005487	49005510	12	-	27260156	SU8686	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.6867181868260395	[267]	[256,386,418,715]	9	hSpCas9	negative selection	8959635
49005305	49005328	12	-	27260156	SU8686	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.36537353886369284	[893]	[1201,1215,892,1239]	6	hSpCas9	negative selection	8959636
49005305	49005328	12	+	27260156	SU8686	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.47768372217076094	[221]	[340,233,381,267]	7	hSpCas9	negative selection	8959637
49005473	49005496	12	+	27260156	SU8686	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.3781052632538209	[733]	[841,830,976,1193]	6	hSpCas9	negative selection	9023893
49013080	49013103	12	-	27260156	SU8686	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.41086505458909794	[251]	[274,114,210,141]	-6	hSpCas9	negative selection	9023894
49005333	49005356	12	+	27260156	SU8686	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.1756737523036751	[430]	[265,320,322,665]	-3	hSpCas9	negative selection	9023895
49005487	49005510	12	-	27260156	SKES1	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.34671611922205575	[267]	[529,219,403,226]	7	hSpCas9	negative selection	9080886
49005305	49005328	12	-	27260156	SKES1	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.11179036518596297	[893]	[934,1099,878,945]	2	hSpCas9	negative selection	9080887
49005305	49005328	12	+	27260156	SKES1	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.13628135984530598	[221]	[439,259,134,174]	3	hSpCas9	negative selection	9080888
49005473	49005496	12	+	27260156	SKES1	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.40282459859193653	[733]	[1225,1087,930,699]	8	hSpCas9	negative selection	9145144
49013080	49013103	12	-	27260156	SKES1	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.12044316883861494	[251]	[201,295,210,218]	-3	hSpCas9	negative selection	9145145
49005333	49005356	12	+	27260156	SKES1	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.04158389534819597	[430]	[387,441,383,447]	-1	hSpCas9	negative selection	9145146
49005487	49005510	12	-	27260156	TOV112D	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.6696645471354172	[267]	[370,393,634,297]	9	hSpCas9	negative selection	9202137
49005305	49005328	12	-	27260156	TOV112D	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.026457042619279836	[893]	[1040,1108,727,829]	0	hSpCas9	negative selection	9202138
49005305	49005328	12	+	27260156	TOV112D	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.09477992932591461	[221]	[328,189,140,178]	-2	hSpCas9	negative selection	9202139
49005473	49005496	12	+	27260156	TOV112D	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.4409170441486081	[733]	[993,1277,837,949]	7	hSpCas9	negative selection	9266395
49013080	49013103	12	-	27260156	TOV112D	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.5608071654992401	[251]	[204,125,141,201]	-8	hSpCas9	negative selection	9266396
49005333	49005356	12	+	27260156	TOV112D	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.20621312524715885	[430]	[353,462,243,452]	-4	hSpCas9	negative selection	9266397
49005487	49005510	12	-	27260156	TC71	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.20374500825766806	[267]	[383,306,312,317]	5	hSpCas9	negative selection	9323388
49005305	49005328	12	-	27260156	TC71	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.007922020066717717	[893]	[839,963,1055,995]	0	hSpCas9	negative selection	9323389
49005305	49005328	12	+	27260156	TC71	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.235363888043301	[221]	[199,376,213,336]	6	hSpCas9	negative selection	9323390
49005473	49005496	12	+	27260156	TC71	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.36774119770470737	[733]	[963,892,979,1239]	8	hSpCas9	negative selection	9387646
49013080	49013103	12	-	27260156	TC71	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.09427610982482915	[251]	[292,287,215,212]	-2	hSpCas9	negative selection	9387647
49005333	49005356	12	+	27260156	TC71	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	-0.01679109387147866	[430]	[395,515,447,468]	0	hSpCas9	negative selection	9387648
49005487	49005510	12	-	27260156	TC32	viability	GTGTACGAGCTGCCCCTTTATGG	PRKAG1	ENSG00000181929	0.44909994213634	[267]	[418,176,475,360]	7	hSpCas9	negative selection	9444639
49005305	49005328	12	-	27260156	TC32	viability	CCGCTACTATAAATCAGCCTTGG	PRKAG1	ENSG00000181929	0.03716020842808032	[893]	[843,699,1032,913]	0	hSpCas9	negative selection	9444640
49005305	49005328	12	+	27260156	TC32	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.23324710879960397	[221]	[199,265,318,186]	4	hSpCas9	negative selection	9444641
49005473	49005496	12	+	27260156	TC32	viability	TGCTTCTTACTATCCCATAAAGG	PRKAG1	ENSG00000181929	0.6325259985412099	[733]	[1007,632,1581,1267]	9	hSpCas9	negative selection	9508897
49013080	49013103	12	-	27260156	TC32	viability	TTCAGATAGCTCCCCAGCTGTGG	PRKAG1	ENSG00000181929	-0.33858108856273605	[251]	[202,117,208,238]	-6	hSpCas9	negative selection	9508898
49005333	49005356	12	+	27260156	TC32	viability	GATATTGATGAAATCAGTGATGG	PRKAG1	ENSG00000181929	0.312018210313634	[430]	[345,475,627,586]	5	hSpCas9	negative selection	9508899
49002988	49003011	12	+	27869803	HPAFII	viability after 27 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.3559793487894891	[537]	[160,270,NaN]	-3	hSpCas9	negative selection	9546926
49003159	49003182	12	-	27869803	HPAFII	viability after 27 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.1152490008540733	[461]	[129,373,NaN]	0	hSpCas9	negative selection	9546927
49004945	49004968	12	+	27869803	HPAFII	viability after 27 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	0.34744187278289473	[94]	[104,28,NaN]	2	hSpCas9	negative selection	9546928
49005288	49005311	12	+	27869803	HPAFII	viability after 27 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-1.0823730196537207	[237]	[51,64,NaN]	-6	hSpCas9	negative selection	9546929
49005739	49005762	12	-	27869803	HPAFII	viability after 27 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	0.834931166410029	[18]	[37,0,NaN]	6	hSpCas9	negative selection	9546930
49018731	49018754	12	-	27869803	HPAFII	viability after 27 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.8381530239995569	[131]	[4,66,NaN]	-5	hSpCas9	negative selection	9546931
49002988	49003011	12	+	27869803	HPAFII	viability after 15 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.010347664610459217	[537]	[459,644,NaN]	0	hSpCas9	negative selection	9629375
49003159	49003182	12	-	27869803	HPAFII	viability after 15 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	-0.06663058163367053	[461]	[454,485,NaN]	0	hSpCas9	negative selection	9629376
49004945	49004968	12	+	27869803	HPAFII	viability after 15 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	0.3925826340016437	[94]	[273,46,NaN]	4	hSpCas9	negative selection	9629377
49005288	49005311	12	+	27869803	HPAFII	viability after 15 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-0.9931079909748467	[237]	[183,93,NaN]	-7	hSpCas9	negative selection	9629378
49005739	49005762	12	-	27869803	HPAFII	viability after 15 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	-1.6811767442160974	[18]	[14,0,NaN]	-9	hSpCas9	negative selection	9629379
49018731	49018754	12	-	27869803	HPAFII	viability after 15 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-1.37272031782253	[131]	[47,58,NaN]	-8	hSpCas9	negative selection	9629380
49002988	49003011	12	+	27869803	ASPC1	viability after 36 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	0.10291239288185994	[1250]	[675,338,421]	1	hSpCas9	negative selection	9711824
49003159	49003182	12	-	27869803	ASPC1	viability after 36 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.4715104438790455	[1177]	[232,725,676]	5	hSpCas9	negative selection	9711825
49004945	49004968	12	+	27869803	ASPC1	viability after 36 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	0.2817684297120393	[170]	[175,24,36]	3	hSpCas9	negative selection	9711826
49005288	49005311	12	+	27869803	ASPC1	viability after 36 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	0.24719998124528836	[583]	[293,261,186]	2	hSpCas9	negative selection	9711827
49005739	49005762	12	-	27869803	ASPC1	viability after 36 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	0.38729086009400415	[55]	[52,7,19]	4	hSpCas9	negative selection	9711828
49018731	49018754	12	-	27869803	ASPC1	viability after 36 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.9826092434288953	[236]	[0,75,42]	-7	hSpCas9	negative selection	9711829
49002988	49003011	12	+	27869803	PATU8988S	viability after 35 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	0.6989053665822763	[1072]	[919,481,NaN]	7	hSpCas9	negative selection	9794273
49003159	49003182	12	-	27869803	PATU8988S	viability after 35 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	-0.22664812787642075	[904]	[310,311,NaN]	-2	hSpCas9	negative selection	9794274
49004945	49004968	12	+	27869803	PATU8988S	viability after 35 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	-0.3885143154587838	[181]	[53,57,NaN]	-4	hSpCas9	negative selection	9794275
49005288	49005311	12	+	27869803	PATU8988S	viability after 35 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	1.1321917875549186	[535]	[550,394,NaN]	9	hSpCas9	negative selection	9794276
49005739	49005762	12	-	27869803	PATU8988S	viability after 35 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	-2.171413604569917	[27]	[3,0,NaN]	-9	hSpCas9	negative selection	9794277
49018731	49018754	12	-	27869803	PATU8988S	viability after 35 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.34254180391770217	[254]	[78,82,NaN]	-4	hSpCas9	negative selection	9794278
49002988	49003011	12	+	27869803	PATU8988S	viability after 31 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	0.6529023678503801	[1072]	[688,651,NaN]	7	hSpCas9	negative selection	9876722
49003159	49003182	12	-	27869803	PATU8988S	viability after 31 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.062454282002952666	[904]	[316,452,NaN]	0	hSpCas9	negative selection	9876723
49004945	49004968	12	+	27869803	PATU8988S	viability after 31 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	-0.06868404689495056	[181]	[55,85,NaN]	-1	hSpCas9	negative selection	9876724
49005288	49005311	12	+	27869803	PATU8988S	viability after 31 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	0.7018542535670995	[535]	[377,308,NaN]	7	hSpCas9	negative selection	9876725
49005739	49005762	12	-	27869803	PATU8988S	viability after 31 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	-3.4808877306076003	[27]	[0,0,NaN]	-9	hSpCas9	negative selection	9876726
49018731	49018754	12	-	27869803	PATU8988S	viability after 31 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.386137537313346	[254]	[90,60,NaN]	-4	hSpCas9	negative selection	9876727
49002988	49003011	12	+	27869803	HPAFII	viability after 35 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.7099783184103139	[537]	[110,228,NaN]	-4	hSpCas9	negative selection	9959171
49003159	49003182	12	-	27869803	HPAFII	viability after 35 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.17053716890636605	[461]	[139,401,NaN]	1	hSpCas9	negative selection	9959172
49004945	49004968	12	+	27869803	HPAFII	viability after 35 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	1.1057474494959658	[94]	[166,31,NaN]	7	hSpCas9	negative selection	9959173
49005288	49005311	12	+	27869803	HPAFII	viability after 35 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-0.18008247784089473	[237]	[95,117,NaN]	-1	hSpCas9	negative selection	9959174
49005739	49005762	12	-	27869803	HPAFII	viability after 35 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	-0.49478016761229604	[18]	[11,0,NaN]	-3	hSpCas9	negative selection	9959175
49018731	49018754	12	-	27869803	HPAFII	viability after 35 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.6093684893524942	[131]	[0,91,NaN]	-4	hSpCas9	negative selection	9959176
49002988	49003011	12	+	27869803	HPAFII	viability after 31 days	CCACTACAAGTCGGTGAACCTGG	PRKAG1	ENSG00000181929	-0.43004634121347385	[537]	[125,330,NaN]	-3	hSpCas9	negative selection	10041620
49003159	49003182	12	-	27869803	HPAFII	viability after 31 days	CTCTGGAGACCATCATCAACAGG	PRKAG1	ENSG00000181929	0.1486818260071231	[461]	[95,495,NaN]	1	hSpCas9	negative selection	10041621
49004945	49004968	12	+	27869803	HPAFII	viability after 31 days	ATGGGTAACTGGAACTCACCTGG	PRKAG1	ENSG00000181929	1.168859613596691	[94]	[183,49,NaN]	8	hSpCas9	negative selection	10041622
49005288	49005311	12	+	27869803	HPAFII	viability after 31 days	TGGGTTAAGGTTCCTTACCAAGG	PRKAG1	ENSG00000181929	-1.2352612926178306	[237]	[61,50,NaN]	-6	hSpCas9	negative selection	10041623
49005739	49005762	12	-	27869803	HPAFII	viability after 31 days	ATTTGATACGTCCCTGCAGGTGG	PRKAG1	ENSG00000181929	0.49987153263386164	[18]	[27,0,NaN]	3	hSpCas9	negative selection	10041624
49018731	49018754	12	-	27869803	HPAFII	viability after 31 days	GGCGCCTCTTGCAATGGAGACGG	PRKAG1	ENSG00000181929	-0.18976529912267703	[131]	[7,126,NaN]	-1	hSpCas9	negative selection	10041625
49003143	49003166	12	-	28162770	P31FUJ	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	0.24068500944433807	[259]	[360]	2	hSpCas9	negative selection	10216980
49003882	49003905	12	+	28162770	P31FUJ	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	0.1960410943894959	[51]	[69]	2	hSpCas9	negative selection	10216981
49003766	49003789	12	-	28162770	P31FUJ	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	-0.3381552045606073	[141]	[131]	-3	hSpCas9	negative selection	10216982
49003805	49003828	12	+	28162770	P31FUJ	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	-1.6161308439658846	[59]	[22]	-7	hSpCas9	negative selection	10216983
49005119	49005142	12	-	28162770	P31FUJ	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	-0.3791916913959017	[113]	[102]	-3	hSpCas9	negative selection	10216984
49004986	49005009	12	+	28162770	P31FUJ	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.6207542274824719	[258]	[467]	7	hSpCas9	negative selection	10216985
49005305	49005328	12	+	28162770	P31FUJ	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.47930132927305	[397]	[651]	5	hSpCas9	negative selection	10216986
49004970	49004993	12	+	28162770	P31FUJ	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	0.373558333219153	[579]	[882]	4	hSpCas9	negative selection	10216987
49004588	49004611	12	-	28162770	P31FUJ	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.3286339092018742	[388]	[363]	-3	hSpCas9	negative selection	10216988
49004572	49004595	12	+	28162770	P31FUJ	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	0.8519782157826409	[189]	[402]	8	hSpCas9	negative selection	10216989
49003143	49003166	12	-	28162770	TF1	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10386346
49003882	49003905	12	+	28162770	TF1	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10386347
49003766	49003789	12	-	28162770	TF1	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10386348
49003805	49003828	12	+	28162770	TF1	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10386349
49005119	49005142	12	-	28162770	TF1	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	NaN	[NaN]	[102]	1	hSpCas9	negative selection	10386350
49004986	49005009	12	+	28162770	TF1	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	NaN	[NaN]	[191]	1	hSpCas9	negative selection	10386351
49005305	49005328	12	+	28162770	TF1	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	NaN	[NaN]	[225]	1	hSpCas9	negative selection	10386352
49004970	49004993	12	+	28162770	TF1	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	NaN	[NaN]	[408]	1	hSpCas9	negative selection	10386353
49004588	49004611	12	-	28162770	TF1	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	NaN	[NaN]	[47]	1	hSpCas9	negative selection	10386354
49004572	49004595	12	+	28162770	TF1	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	NaN	[NaN]	[229]	1	hSpCas9	negative selection	10386355
49003143	49003166	12	-	28162770	SKM1	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	0.06657701930957144	[73]	[136]	0	hSpCas9	negative selection	10555712
49003882	49003905	12	+	28162770	SKM1	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	-0.38142910663602425	[13]	[18]	-3	hSpCas9	negative selection	10555713
49003766	49003789	12	-	28162770	SKM1	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	0.3155018257279294	[24]	[54]	3	hSpCas9	negative selection	10555714
49003805	49003828	12	+	28162770	SKM1	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	-0.7516123701306074	[19]	[20]	-5	hSpCas9	negative selection	10555715
49005119	49005142	12	-	28162770	SKM1	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	0.9435330483409714	[39]	[135]	8	hSpCas9	negative selection	10555716
49004986	49005009	12	+	28162770	SKM1	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	-0.2266225813555109	[91]	[138]	-2	hSpCas9	negative selection	10555717
49005305	49005328	12	+	28162770	SKM1	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.027470816321985003	[112]	[195]	0	hSpCas9	negative selection	10555718
49004970	49004993	12	+	28162770	SKM1	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	0.6461471377164008	[119]	[331]	6	hSpCas9	negative selection	10555719
49004588	49004611	12	-	28162770	SKM1	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.9461811092427355	[96]	[88]	-6	hSpCas9	negative selection	10555720
49004572	49004595	12	+	28162770	SKM1	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	0.4798886436288117	[57]	[142]	4	hSpCas9	negative selection	10555721
49003143	49003166	12	-	28162770	SKM1	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	0.06657701930957144	[73]	[136]	0	hSpCas9	negative selection	10725078
49003882	49003905	12	+	28162770	SKM1	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	-0.38142910663602425	[13]	[18]	-3	hSpCas9	negative selection	10725079
49003766	49003789	12	-	28162770	SKM1	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	0.3155018257279294	[24]	[54]	3	hSpCas9	negative selection	10725080
49003805	49003828	12	+	28162770	SKM1	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	-0.7516123701306074	[19]	[20]	-5	hSpCas9	negative selection	10725081
49005119	49005142	12	-	28162770	SKM1	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	0.9435330483409714	[39]	[135]	8	hSpCas9	negative selection	10725082
49004986	49005009	12	+	28162770	SKM1	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	-0.2266225813555109	[91]	[138]	-2	hSpCas9	negative selection	10725083
49005305	49005328	12	+	28162770	SKM1	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.027470816321985003	[112]	[195]	0	hSpCas9	negative selection	10725084
49004970	49004993	12	+	28162770	SKM1	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	0.6461471377164008	[119]	[331]	6	hSpCas9	negative selection	10725085
49004588	49004611	12	-	28162770	SKM1	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.9461811092427355	[96]	[88]	-6	hSpCas9	negative selection	10725086
49004572	49004595	12	+	28162770	SKM1	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	0.4798886436288117	[57]	[142]	4	hSpCas9	negative selection	10725087
49003143	49003166	12	-	28162770	PL21	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	0.22670933489322265	[268]	[136]	2	hSpCas9	negative selection	10894444
49003882	49003905	12	+	28162770	PL21	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	-1.6411626394916214	[42]	[5]	-8	hSpCas9	negative selection	10894445
49003766	49003789	12	-	28162770	PL21	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	0.5166132792845743	[158]	[98]	4	hSpCas9	negative selection	10894446
49003805	49003828	12	+	28162770	PL21	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	-2.01487327648153	[64]	[6]	-8	hSpCas9	negative selection	10894447
49005119	49005142	12	-	28162770	PL21	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	-0.24237862121163067	[105]	[38]	-2	hSpCas9	negative selection	10894448
49004986	49005009	12	+	28162770	PL21	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	-0.5934095080432533	[259]	[74]	-4	hSpCas9	negative selection	10894449
49005305	49005328	12	+	28162770	PL21	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.8739113821683323	[251]	[200]	7	hSpCas9	negative selection	10894450
49004970	49004993	12	+	28162770	PL21	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	0.2517408109765329	[356]	[184]	2	hSpCas9	negative selection	10894451
49004588	49004611	12	-	28162770	PL21	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-1.2434670369862943	[271]	[49]	-7	hSpCas9	negative selection	10894452
49004572	49004595	12	+	28162770	PL21	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	0.07814909011070986	[147]	[67]	0	hSpCas9	negative selection	10894453
49003143	49003166	12	-	28162770	P31FUJ	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	0.24068500944433807	[259]	[360]	2	hSpCas9	negative selection	11063810
49003882	49003905	12	+	28162770	P31FUJ	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	0.1960410943894959	[51]	[69]	2	hSpCas9	negative selection	11063811
49003766	49003789	12	-	28162770	P31FUJ	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	-0.3381552045606073	[141]	[131]	-3	hSpCas9	negative selection	11063812
49003805	49003828	12	+	28162770	P31FUJ	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	-1.6161308439658846	[59]	[22]	-7	hSpCas9	negative selection	11063813
49005119	49005142	12	-	28162770	P31FUJ	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	-0.3791916913959017	[113]	[102]	-3	hSpCas9	negative selection	11063814
49004986	49005009	12	+	28162770	P31FUJ	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.6207542274824719	[258]	[467]	7	hSpCas9	negative selection	11063815
49005305	49005328	12	+	28162770	P31FUJ	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.47930132927305	[397]	[651]	5	hSpCas9	negative selection	11063816
49004970	49004993	12	+	28162770	P31FUJ	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	0.373558333219153	[579]	[882]	4	hSpCas9	negative selection	11063817
49004588	49004611	12	-	28162770	P31FUJ	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.3286339092018742	[388]	[363]	-3	hSpCas9	negative selection	11063818
49004572	49004595	12	+	28162770	P31FUJ	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	0.8519782157826409	[189]	[402]	8	hSpCas9	negative selection	11063819
49003143	49003166	12	-	28162770	OCIAML5	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	-0.05455943476274015	[125]	[218]	0	hSpCas9	negative selection	11233176
49003882	49003905	12	+	28162770	OCIAML5	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	0.43033315983672793	[36]	[89]	3	hSpCas9	negative selection	11233177
49003766	49003789	12	-	28162770	OCIAML5	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	0.13544248495280609	[57]	[114]	1	hSpCas9	negative selection	11233178
49003805	49003828	12	+	28162770	OCIAML5	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	-3.902692643933965	[57]	[6]	-9	hSpCas9	negative selection	11233179
49005119	49005142	12	-	28162770	OCIAML5	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	0.17287978626623396	[85]	[174]	1	hSpCas9	negative selection	11233180
49004986	49005009	12	+	28162770	OCIAML5	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.8285312089076683	[106]	[342]	7	hSpCas9	negative selection	11233181
49005305	49005328	12	+	28162770	OCIAML5	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.15353613536537902	[256]	[515]	1	hSpCas9	negative selection	11233182
49004970	49004993	12	+	28162770	OCIAML5	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	0.7513528345647201	[232]	[707]	6	hSpCas9	negative selection	11233183
49004588	49004611	12	-	28162770	OCIAML5	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.5176475317934378	[206]	[260]	-4	hSpCas9	negative selection	11233184
49004572	49004595	12	+	28162770	OCIAML5	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	0.4483283624737241	[107]	[265]	4	hSpCas9	negative selection	11233185
49003143	49003166	12	-	28162770	EOL1	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	-0.3700222076963662	[443]	[180]	-3	hSpCas9	negative selection	11402542
49003882	49003905	12	+	28162770	EOL1	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	0.2354768675086396	[78]	[48]	2	hSpCas9	negative selection	11402543
49003766	49003789	12	-	28162770	EOL1	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	0.1234518399846129	[229]	[131]	1	hSpCas9	negative selection	11402544
49003805	49003828	12	+	28162770	EOL1	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	0.04769600234339921	[100]	[54]	0	hSpCas9	negative selection	11402545
49005119	49005142	12	-	28162770	EOL1	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	-0.26186535266034694	[263]	[115]	-2	hSpCas9	negative selection	11402546
49004986	49005009	12	+	28162770	EOL1	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.07054275621410905	[384]	[212]	0	hSpCas9	negative selection	11402547
49005305	49005328	12	+	28162770	EOL1	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.25273485692957914	[367]	[230]	2	hSpCas9	negative selection	11402548
49004970	49004993	12	+	28162770	EOL1	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	-0.15848406090559813	[446]	[210]	-1	hSpCas9	negative selection	11402549
49004588	49004611	12	-	28162770	EOL1	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.310668690123497	[338]	[143]	-2	hSpCas9	negative selection	11402550
49004572	49004595	12	+	28162770	EOL1	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	-0.025078705914346244	[196]	[101]	0	hSpCas9	negative selection	11402551
49003143	49003166	12	-	28162770	MOLM13	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	1.1986364529756277	[278]	[462]	8	hSpCas9	negative selection	11571908
49003882	49003905	12	+	28162770	MOLM13	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	0.15238755581664964	[55]	[44]	1	hSpCas9	negative selection	11571909
49003766	49003789	12	-	28162770	MOLM13	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	0.4678893815445787	[215]	[215]	3	hSpCas9	negative selection	11571910
49003805	49003828	12	+	28162770	MOLM13	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	1.885046932697792	[84]	[226]	9	hSpCas9	negative selection	11571911
49005119	49005142	12	-	28162770	MOLM13	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	0.13792396759179834	[224]	[178]	1	hSpCas9	negative selection	11571912
49004986	49005009	12	+	28162770	MOLM13	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.43301892169752654	[334]	[326]	3	hSpCas9	negative selection	11571913
49005305	49005328	12	+	28162770	MOLM13	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.618065121938622	[473]	[525]	4	hSpCas9	negative selection	11571914
49004970	49004993	12	+	28162770	MOLM13	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	-0.07920493358613434	[563]	[385]	0	hSpCas9	negative selection	11571915
49004588	49004611	12	-	28162770	MOLM13	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-1.0589389431918217	[607]	[210]	-5	hSpCas9	negative selection	11571916
49004572	49004595	12	+	28162770	MOLM13	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	-1.0137624019342815	[228]	[81]	-5	hSpCas9	negative selection	11571917
49003143	49003166	12	-	28162770	HEL	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	-0.28786783258196913	[344]	[180]	-2	hSpCas9	negative selection	11741274
49003882	49003905	12	+	28162770	HEL	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	-1.3312659594666982	[54]	[13]	-6	hSpCas9	negative selection	11741275
49003766	49003789	12	-	28162770	HEL	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	-0.055232630549985506	[145]	[89]	0	hSpCas9	negative selection	11741276
49003805	49003828	12	+	28162770	HEL	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	-0.05059982976559119	[75]	[46]	0	hSpCas9	negative selection	11741277
49005119	49005142	12	-	28162770	HEL	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	-0.31603850527313004	[137]	[70]	-2	hSpCas9	negative selection	11741278
49004986	49005009	12	+	28162770	HEL	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.16908116628529418	[292]	[210]	1	hSpCas9	negative selection	11741279
49005305	49005328	12	+	28162770	HEL	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.11303144326942116	[396]	[274]	0	hSpCas9	negative selection	11741280
49004970	49004993	12	+	28162770	HEL	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	0.26033233696147984	[407]	[312]	2	hSpCas9	negative selection	11741281
49004588	49004611	12	-	28162770	HEL	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-1.9977187813125028	[423]	[67]	-8	hSpCas9	negative selection	11741282
49004572	49004595	12	+	28162770	HEL	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	-0.1550723173863762	[225]	[129]	-1	hSpCas9	negative selection	11741283
49003143	49003166	12	-	28162770	MV411	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	0.7520266350399116	[202]	[287]	6	hSpCas9	negative selection	11910640
49003882	49003905	12	+	28162770	MV411	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	-1.936987020354652	[49]	[10]	-8	hSpCas9	negative selection	11910641
49003766	49003789	12	-	28162770	MV411	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	-1.4459011109831728	[151]	[46]	-7	hSpCas9	negative selection	11910642
49003805	49003828	12	+	28162770	MV411	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	-4.861086905995394	[68]	[1]	-9	hSpCas9	negative selection	11910643
49005119	49005142	12	-	28162770	MV411	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	-0.24409808597011196	[141]	[100]	-2	hSpCas9	negative selection	11910644
49004986	49005009	12	+	28162770	MV411	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.39052450672987016	[210]	[232]	3	hSpCas9	negative selection	11910645
49005305	49005328	12	+	28162770	MV411	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.3885652879176528	[252]	[278]	3	hSpCas9	negative selection	11910646
49004970	49004993	12	+	28162770	MV411	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	0.8437375954382124	[337]	[510]	7	hSpCas9	negative selection	11910647
49004588	49004611	12	-	28162770	MV411	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-0.4706240856585478	[277]	[168]	-3	hSpCas9	negative selection	11910648
49004572	49004595	12	+	28162770	MV411	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	0.6647559913128575	[157]	[210]	6	hSpCas9	negative selection	11910649
49003143	49003166	12	-	28162770	MONOMAC1	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	-0.24843599956619788	[199]	[192]	-2	hSpCas9	negative selection	12080006
49003882	49003905	12	+	28162770	MONOMAC1	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	-0.24434256183791025	[30]	[29]	-2	hSpCas9	negative selection	12080007
49003766	49003789	12	-	28162770	MONOMAC1	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	-1.184545902876357	[114]	[57]	-7	hSpCas9	negative selection	12080008
49003805	49003828	12	+	28162770	MONOMAC1	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	-0.5485092175609314	[36]	[28]	-5	hSpCas9	negative selection	12080009
49005119	49005142	12	-	28162770	MONOMAC1	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	-0.48654346425453854	[76]	[62]	-4	hSpCas9	negative selection	12080010
49004986	49005009	12	+	28162770	MONOMAC1	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	-0.10715134354235842	[139]	[148]	-1	hSpCas9	negative selection	12080011
49005305	49005328	12	+	28162770	MONOMAC1	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	-0.062240069020843	[193]	[212]	0	hSpCas9	negative selection	12080012
49004970	49004993	12	+	28162770	MONOMAC1	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	0.10781773446886722	[203]	[251]	1	hSpCas9	negative selection	12080013
49004588	49004611	12	-	28162770	MONOMAC1	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	0.18782250355426544	[156]	[204]	2	hSpCas9	negative selection	12080014
49004572	49004595	12	+	28162770	MONOMAC1	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	-0.45419468655667833	[97]	[81]	-4	hSpCas9	negative selection	12080015
49003143	49003166	12	-	28162770	OCIAML2	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	-0.8929721251442384	[65]	[196]	-6	hSpCas9	negative selection	12249372
49003882	49003905	12	+	28162770	OCIAML2	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	-2.2482374039057134	[11]	[13]	-8	hSpCas9	negative selection	12249373
49003766	49003789	12	-	28162770	OCIAML2	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	-0.767022828022386	[34]	[113]	-5	hSpCas9	negative selection	12249374
49003805	49003828	12	+	28162770	OCIAML2	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	1.2735312703282489	[4]	[66]	9	hSpCas9	negative selection	12249375
49005119	49005142	12	-	28162770	OCIAML2	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	0.7817573363921242	[16]	[161]	7	hSpCas9	negative selection	12249376
49004986	49005009	12	+	28162770	OCIAML2	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	0.3737193042976445	[43]	[315]	3	hSpCas9	negative selection	12249377
49005305	49005328	12	+	28162770	OCIAML2	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	1.1714765825826037	[32]	[411]	9	hSpCas9	negative selection	12249378
49004970	49004993	12	+	28162770	OCIAML2	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	0.147691272425426	[56]	[349]	1	hSpCas9	negative selection	12249379
49004588	49004611	12	-	28162770	OCIAML2	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	0.7419815753017013	[36]	[342]	7	hSpCas9	negative selection	12249380
49004572	49004595	12	+	28162770	OCIAML2	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	1.0187550154967637	[25]	[291]	8	hSpCas9	negative selection	12249381
49003143	49003166	12	-	28162770	OCIAML3	viability	CAACAGGCTAGTGGAAGCAGAGG	PRKAG1	ENSG00000181929	-0.3118058237524118	[80]	[196]	-2	hSpCas9	negative selection	12418738
49003882	49003905	12	+	28162770	OCIAML3	viability	AGAGACTTGGACATGAACTCTGG	PRKAG1	ENSG00000181929	0.7983097824545973	[7]	[41]	7	hSpCas9	negative selection	12418739
49003766	49003789	12	-	28162770	OCIAML3	viability	AGTCTCAGCCCTGCCAGTGGTGG	PRKAG1	ENSG00000181929	-0.16104823304805693	[29]	[80]	-1	hSpCas9	negative selection	12418740
49003805	49003828	12	+	28162770	OCIAML3	viability	TCCCCAGAGCCACATAGACGGGG	PRKAG1	ENSG00000181929	-4.256972653046593	[18]	[2]	-9	hSpCas9	negative selection	12418741
49005119	49005142	12	-	28162770	OCIAML3	viability	CACAAGATAGAAACTTGGAGAGG	PRKAG1	ENSG00000181929	-1.2389126815016014	[42]	[54]	-7	hSpCas9	negative selection	12418742
49004986	49005009	12	+	28162770	OCIAML3	viability	CAAGCGGTTTAAAGGAGTCCTGG	PRKAG1	ENSG00000181929	-0.028410464469938	[99]	[295]	0	hSpCas9	negative selection	12418743
49005305	49005328	12	+	28162770	OCIAML3	viability	CCAAGGCTGATTTATAGTAGCGG	PRKAG1	ENSG00000181929	0.6105072902820288	[86]	[400]	5	hSpCas9	negative selection	12418744
49004970	49004993	12	+	28162770	OCIAML3	viability	TTAGGAGAAATGCAGACAAGCGG	PRKAG1	ENSG00000181929	-0.1826932270880367	[96]	[257]	-1	hSpCas9	negative selection	12418745
49004588	49004611	12	-	28162770	OCIAML3	viability	TAATTCGGAACAAGATCCACAGG	PRKAG1	ENSG00000181929	-1.4403844512109514	[88]	[98]	-7	hSpCas9	negative selection	12418746
49004572	49004595	12	+	28162770	OCIAML3	viability	GGTCAATAACTGGCAGCCTGTGG	PRKAG1	ENSG00000181929	-1.5527849775976503	[68]	[70]	-8	hSpCas9	negative selection	12418747