Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5592
• Symbol: PRKG1
• Description: protein kinase cGMP-dependent 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PRKG1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
52062610	52062633	10	+	26472758	Jiyoye	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	0.1526025544202756	[203]	[170]	1	hSpCas9	negative selection	127523
51153242	51153265	10	+	26472758	Jiyoye	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	2.866607000143171	[7]	[43]	9	hSpCas9	negative selection	127524
51153254	51153277	10	+	26472758	Jiyoye	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.7997425999810224	[274]	[360]	5	hSpCas9	negative selection	127525
51153285	51153308	10	+	26472758	Jiyoye	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	-1.2473280524683596	[84]	[26]	-7	hSpCas9	negative selection	127526
51907540	51907563	10	-	26472758	Jiyoye	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	0.727842930187319	[228]	[285]	5	hSpCas9	negative selection	127527
52062610	52062633	10	+	26472758	KBM7	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	-0.4687719537247318	[572,342]	[220,90]	-4	hSpCas9	negative selection	318641
51153242	51153265	10	+	26472758	KBM7	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	-0.09009442961331193	[226,87]	[89,45]	-1	hSpCas9	negative selection	318642
51153254	51153277	10	+	26472758	KBM7	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.2118361875742738	[1800,1153]	[875,713]	2	hSpCas9	negative selection	318643
51153285	51153308	10	+	26472758	KBM7	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	-0.013238684274976653	[221,309]	[161,94]	0	hSpCas9	negative selection	318644
51907540	51907563	10	-	26472758	KBM7	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	-0.18594306425104867	[994,878]	[391,381]	-2	hSpCas9	negative selection	318645
52062610	52062633	10	+	26472758	Raji	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	0.3748638462385856	[215]	[64]	3	hSpCas9	negative selection	509759
51153242	51153265	10	+	26472758	Raji	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.9477268693851142	[104]	[46]	8	hSpCas9	negative selection	509760
51153254	51153277	10	+	26472758	Raji	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.3833569969148911	[739]	[223]	3	hSpCas9	negative selection	509761
51153285	51153308	10	+	26472758	Raji	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	0.09615627995034526	[128]	[31]	0	hSpCas9	negative selection	509762
51907540	51907563	10	-	26472758	Raji	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	0.2623581953499403	[484]	[134]	2	hSpCas9	negative selection	509763
52062610	52062633	10	+	26472758	K562	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	-0.7513812838042673	[342]	[171]	-4	hSpCas9	negative selection	700877
51153242	51153265	10	+	26472758	K562	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.9606257616658556	[97]	[160]	7	hSpCas9	negative selection	700878
51153254	51153277	10	+	26472758	K562	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.29423462128417754	[1166]	[1207]	2	hSpCas9	negative selection	700879
51153285	51153308	10	+	26472758	K562	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	-0.46523952050402384	[156]	[95]	-3	hSpCas9	negative selection	700880
51907540	51907563	10	-	26472758	K562	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	-0.05017228260027029	[757]	[617]	0	hSpCas9	negative selection	700881
50991520	50991543	10	-	26627737	DLD1	viability	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-0.8912963053551751	[846]	[123,248,70]	-7	hSpCas9	negative selection	775110
51074866	51074889	10	-	26627737	DLD1	viability	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	0.7797313015095748	[74]	[31,82,11]	7	hSpCas9	negative selection	775111
51153284	51153307	10	+	26627737	DLD1	viability	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	0.3149831338048593	[308]	[86,177,100]	3	hSpCas9	negative selection	775112
51467748	51467771	10	+	26627737	DLD1	viability	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	-0.4124904624656911	[1656]	[260,415,477]	-4	hSpCas9	negative selection	775113
52054509	52054532	10	+	26627737	DLD1	viability	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.21516194428992041	[570]	[263,182,177]	2	hSpCas9	negative selection	775120
50991520	50991543	10	-	26627737	GBM cells	viability after 5 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	0.19847415674459334	[350]	[240,190]	3	hSpCas9	negative selection	857425
51074866	51074889	10	-	26627737	GBM cells	viability after 5 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	-1.5161236243931584	[71]	[15,10]	-9	hSpCas9	negative selection	857426
51153284	51153307	10	+	26627737	GBM cells	viability after 5 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-0.33392029317240923	[415]	[180,172]	-5	hSpCas9	negative selection	857427
51467748	51467771	10	+	26627737	GBM cells	viability after 5 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.27652296758705996	[614]	[412,385]	4	hSpCas9	negative selection	857428
52054509	52054532	10	+	26627737	GBM cells	viability after 5 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.6186731536455525	[387]	[320,317]	8	hSpCas9	negative selection	857435
50991520	50991543	10	-	26627737	GBM cells	viability after 13 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	0.20514297319693442	[350]	[277,171]	2	hSpCas9	negative selection	939740
51074866	51074889	10	-	26627737	GBM cells	viability after 13 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	-0.5755983577829542	[71]	[39,14]	-6	hSpCas9	negative selection	939741
51153284	51153307	10	+	26627737	GBM cells	viability after 13 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-0.21111508544681168	[415]	[237,159]	-3	hSpCas9	negative selection	939742
51467748	51467771	10	+	26627737	GBM cells	viability after 13 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.3536146831218214	[614]	[550,324]	4	hSpCas9	negative selection	939743
52054509	52054532	10	+	26627737	GBM cells	viability after 13 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.5099123898910802	[387]	[328,275]	6	hSpCas9	negative selection	939750
50991520	50991543	10	-	26627737	GBM cells	viability after 21 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-0.32390084079190495	[350]	[155,148]	-3	hSpCas9	negative selection	1022055
51074866	51074889	10	-	26627737	GBM cells	viability after 21 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	-1.9065634505025542	[71]	[11,8]	-8	hSpCas9	negative selection	1022056
51153284	51153307	10	+	26627737	GBM cells	viability after 21 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-0.5526914279080182	[415]	[163,144]	-5	hSpCas9	negative selection	1022057
51467748	51467771	10	+	26627737	GBM cells	viability after 21 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.5005039293555644	[614]	[491,454]	5	hSpCas9	negative selection	1022058
52054509	52054532	10	+	26627737	GBM cells	viability after 21 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.6925374376449958	[387]	[371,311]	7	hSpCas9	negative selection	1022065
50991520	50991543	10	-	26627737	RPE1	viability after 9 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	0.07166391391929472	[1277]	[440,393]	0	hSpCas9	negative selection	1104370
51074866	51074889	10	-	26627737	RPE1	viability after 9 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	1.5339481184779444	[108]	[69,135]	8	hSpCas9	negative selection	1104371
51153284	51153307	10	+	26627737	RPE1	viability after 9 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-1.1477787880865757	[1849]	[301,208]	-7	hSpCas9	negative selection	1104372
51467748	51467771	10	+	26627737	RPE1	viability after 9 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.6020606063845295	[1622]	[648,928]	4	hSpCas9	negative selection	1104373
52054509	52054532	10	+	26627737	RPE1	viability after 9 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.7676433429690128	[1366]	[532,980]	5	hSpCas9	negative selection	1104380
50991520	50991543	10	-	26627737	RPE1	viability after 12 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-0.418417405997897	[1277]	[304,205]	-3	hSpCas9	negative selection	1186685
51074866	51074889	10	-	26627737	RPE1	viability after 12 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	1.3018540188960204	[108]	[78,64]	7	hSpCas9	negative selection	1186686
51153284	51153307	10	+	26627737	RPE1	viability after 12 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-1.368162350196242	[1849]	[244,136]	-7	hSpCas9	negative selection	1186687
51467748	51467771	10	+	26627737	RPE1	viability after 12 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.5514007534505843	[1622]	[809,457]	3	hSpCas9	negative selection	1186688
52054509	52054532	10	+	26627737	RPE1	viability after 12 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.7543076244748721	[1366]	[687,546]	5	hSpCas9	negative selection	1186695
50991520	50991543	10	-	26627737	RPE1	viability after 15 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-0.4198267903056984	[1277]	[312,228]	-3	hSpCas9	negative selection	1269000
51074866	51074889	10	-	26627737	RPE1	viability after 15 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	1.4826730248209912	[108]	[160,13]	7	hSpCas9	negative selection	1269001
51153284	51153307	10	+	26627737	RPE1	viability after 15 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-1.9588611929531807	[1849]	[99,167]	-8	hSpCas9	negative selection	1269002
51467748	51467771	10	+	26627737	RPE1	viability after 15 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.8512418111585263	[1622]	[1122,543]	5	hSpCas9	negative selection	1269003
52054509	52054532	10	+	26627737	RPE1	viability after 15 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.911880403947634	[1366]	[723,730]	5	hSpCas9	negative selection	1269010
50991520	50991543	10	-	26627737	RPE1	viability after 18 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-0.4322223846304544	[1277]	[214,298]	-3	hSpCas9	negative selection	1351315
51074866	51074889	10	-	26627737	RPE1	viability after 18 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	1.0051696037030515	[108]	[1,119]	6	hSpCas9	negative selection	1351316
51153284	51153307	10	+	26627737	RPE1	viability after 18 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-0.8386624978375183	[1849]	[283,273]	-5	hSpCas9	negative selection	1351317
51467748	51467771	10	+	26627737	RPE1	viability after 18 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.6531245866260684	[1622]	[798,570]	4	hSpCas9	negative selection	1351318
52054509	52054532	10	+	26627737	RPE1	viability after 18 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.7429722729937711	[1366]	[614,619]	4	hSpCas9	negative selection	1351325
50991520	50991543	10	-	26627737	HeLa	viability after 8 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-1.1966354111492528	[1093]	[199,296,129]	-8	hSpCas9	negative selection	1433630
51074866	51074889	10	-	26627737	HeLa	viability after 8 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	-0.2502967145485959	[167]	[36,50,88]	-2	hSpCas9	negative selection	1433631
51153284	51153307	10	+	26627737	HeLa	viability after 8 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	0.6239270461303694	[416]	[226,256,338]	5	hSpCas9	negative selection	1433632
51467748	51467771	10	+	26627737	HeLa	viability after 8 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	-0.12701604236799646	[1286]	[649,573,355]	-1	hSpCas9	negative selection	1433633
52054509	52054532	10	+	26627737	HeLa	viability after 8 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.5299985239139098	[512]	[284,458,221]	5	hSpCas9	negative selection	1433640
50991520	50991543	10	-	26627737	HeLa	viability after 12 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-0.8228353276195056	[1093]	[181,204,382]	-6	hSpCas9	negative selection	1515945
51074866	51074889	10	-	26627737	HeLa	viability after 12 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	-2.591040680541389	[167]	[0,13,18]	-9	hSpCas9	negative selection	1515946
51153284	51153307	10	+	26627737	HeLa	viability after 12 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-0.02317154506039823	[416]	[139,262,94]	0	hSpCas9	negative selection	1515947
51467748	51467771	10	+	26627737	HeLa	viability after 12 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	-0.27065440402594154	[1286]	[378,552,376]	-2	hSpCas9	negative selection	1515948
52054509	52054532	10	+	26627737	HeLa	viability after 12 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.35252915681964675	[512]	[265,269,275]	3	hSpCas9	negative selection	1515955
50991520	50991543	10	-	26627737	HeLa	viability after 15 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-1.3869093046073133	[1093]	[55,181,282]	-8	hSpCas9	negative selection	1598260
51074866	51074889	10	-	26627737	HeLa	viability after 15 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	-0.8249196916570869	[167]	[37,0,79]	-6	hSpCas9	negative selection	1598261
51153284	51153307	10	+	26627737	HeLa	viability after 15 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-0.0011538452694578039	[416]	[218,194,87]	0	hSpCas9	negative selection	1598262
51467748	51467771	10	+	26627737	HeLa	viability after 15 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	-0.5578941089345939	[1286]	[273,387,410]	-5	hSpCas9	negative selection	1598263
52054509	52054532	10	+	26627737	HeLa	viability after 15 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.86922960718125	[512]	[483,351,300]	6	hSpCas9	negative selection	1598270
50991520	50991543	10	-	26627737	HeLa	viability after 18 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-1.364158634414856	[1093]	[36,157,282]	-8	hSpCas9	negative selection	1680575
51074866	51074889	10	-	26627737	HeLa	viability after 18 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	-0.890938323312586	[167]	[21,0,79]	-7	hSpCas9	negative selection	1680576
51153284	51153307	10	+	26627737	HeLa	viability after 18 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-0.016600733438749682	[416]	[142,161,87]	0	hSpCas9	negative selection	1680577
51467748	51467771	10	+	26627737	HeLa	viability after 18 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	-0.5112760928254236	[1286]	[197,331,410]	-4	hSpCas9	negative selection	1680578
52054509	52054532	10	+	26627737	HeLa	viability after 18 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.8223599902518215	[512]	[306,283,300]	6	hSpCas9	negative selection	1680585
50991520	50991543	10	-	26627737	HCT116	viability after 6 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-1.5594451672881087	[1659]	[45,111]	-7	hSpCas9	negative selection	1762890
51074866	51074889	10	-	26627737	HCT116	viability after 6 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	-2.8742344319300077	[457]	[23,1]	-9	hSpCas9	negative selection	1762891
51153284	51153307	10	+	26627737	HCT116	viability after 6 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	2.0020013587911727	[443]	[82,387]	8	hSpCas9	negative selection	1762892
51467748	51467771	10	+	26627737	HCT116	viability after 6 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	-0.0985143928922374	[1334]	[215,184]	0	hSpCas9	negative selection	1762893
52054509	52054532	10	+	26627737	HCT116	viability after 6 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.302107759771641	[771]	[206,117]	1	hSpCas9	negative selection	1762900
50991520	50991543	10	-	26627737	HCT116	viability after 8 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-0.36663342613907757	[346]	[49,150,240]	-4	hSpCas9	negative selection	1845205
51074866	51074889	10	-	26627737	HCT116	viability after 8 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	0.8990016078530196	[35]	[34,43,31]	7	hSpCas9	negative selection	1845206
51153284	51153307	10	+	26627737	HCT116	viability after 8 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	0.14527820582344997	[316]	[230,137,210]	1	hSpCas9	negative selection	1845207
51467748	51467771	10	+	26627737	HCT116	viability after 8 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.632293980806499	[584]	[534,498,465]	6	hSpCas9	negative selection	1845208
52054509	52054532	10	+	26627737	HCT116	viability after 8 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	-0.23943362563226767	[495]	[251,218,223]	-3	hSpCas9	negative selection	1845215
50991520	50991543	10	-	26627737	HCT116	viability after 9 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-0.26203720983518863	[1659]	[582,200]	-2	hSpCas9	negative selection	1927520
51074866	51074889	10	-	26627737	HCT116	viability after 9 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	-2.5782478742757338	[457]	[34,8]	-9	hSpCas9	negative selection	1927521
51153284	51153307	10	+	26627737	HCT116	viability after 9 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	0.9578147368514591	[443]	[136,303]	6	hSpCas9	negative selection	1927522
51467748	51467771	10	+	26627737	HCT116	viability after 9 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.3859102914688688	[1334]	[338,565]	3	hSpCas9	negative selection	1927523
52054509	52054532	10	+	26627737	HCT116	viability after 9 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	-0.050581377713576736	[771]	[212,187]	0	hSpCas9	negative selection	1927530
50991520	50991543	10	-	26627737	HCT116	viability after 12 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	0.3101896315217241	[346]	[301,199,168]	3	hSpCas9	negative selection	2009835
51074866	51074889	10	-	26627737	HCT116	viability after 12 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	1.258449348436928	[35]	[24,21,89]	8	hSpCas9	negative selection	2009836
51153284	51153307	10	+	26627737	HCT116	viability after 12 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-0.05796022361790835	[316]	[157,189,132]	0	hSpCas9	negative selection	2009837
51467748	51467771	10	+	26627737	HCT116	viability after 12 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.4721433779792322	[584]	[322,406,557]	4	hSpCas9	negative selection	2009838
52054509	52054532	10	+	26627737	HCT116	viability after 12 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.208298784351315	[495]	[310,400,192]	2	hSpCas9	negative selection	2009845
50991520	50991543	10	-	26627737	HCT116	viability after 15 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	0.21727921452459378	[346]	[233,370,91]	2	hSpCas9	negative selection	2092150
51074866	51074889	10	-	26627737	HCT116	viability after 15 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	1.0143320276062995	[35]	[22,57,41]	8	hSpCas9	negative selection	2092151
51153284	51153307	10	+	26627737	HCT116	viability after 15 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	0.43717114810323154	[316]	[276,204,260]	4	hSpCas9	negative selection	2092152
51467748	51467771	10	+	26627737	HCT116	viability after 15 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.15391183931969155	[584]	[478,267,386]	1	hSpCas9	negative selection	2092153
52054509	52054532	10	+	26627737	HCT116	viability after 15 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.0253872239009435	[495]	[335,304,234]	0	hSpCas9	negative selection	2092160
50991520	50991543	10	-	26627737	HCT116	viability after 18 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	0.29472748332822873	[346]	[265,183,166]	2	hSpCas9	negative selection	2174465
51074866	51074889	10	-	26627737	HCT116	viability after 18 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	1.6561231894044601	[35]	[28,35,102]	9	hSpCas9	negative selection	2174466
51153284	51153307	10	+	26627737	HCT116	viability after 18 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	0.23781073899395216	[316]	[155,234,145]	2	hSpCas9	negative selection	2174467
51467748	51467771	10	+	26627737	HCT116	viability after 18 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.5966317368049247	[584]	[445,231,626]	5	hSpCas9	negative selection	2174468
52054509	52054532	10	+	26627737	HCT116	viability after 18 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.5015896929115856	[495]	[284,442,280]	4	hSpCas9	negative selection	2174475
51153149	51153172	10	+	24336569	HL60	viability	CCTCTCTTGCCATAGGTCCAAGG	PRKG1	ENSG00000185532	0.9486216255603952	[521]	[2131]	7	hSpCas9	negative selection	2286522
51153161	51153184	10	+	24336569	HL60	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.4850787766476221	[628]	[950]	-4	hSpCas9	negative selection	2286523
51153166	51153189	10	-	24336569	HL60	viability	AGCTTCCTTTATAAGATCCTTGG	PRKG1	ENSG00000185532	0.37180653338172687	[255]	[700]	3	hSpCas9	negative selection	2286524
51153191	51153214	10	-	24336569	HL60	viability	TCTTCATAAAGTCATTGTCAAGG	PRKG1	ENSG00000185532	0.5787270311373018	[410]	[1298]	5	hSpCas9	negative selection	2286525
51153197	51153220	10	+	24336569	HL60	viability	CAATGACTTTATGAAGAACTTGG	PRKG1	ENSG00000185532	1.8082459686739352	[213]	[1585]	9	hSpCas9	negative selection	2286526
51153215	51153238	10	+	24336569	HL60	viability	CTTGGAGCTGTCGCAGATCCAGG	PRKG1	ENSG00000185532	0.9173489844206615	[303]	[1214]	7	hSpCas9	negative selection	2286527
51153224	51153247	10	+	24336569	HL60	viability	GTCGCAGATCCAGGAGATTGTGG	PRKG1	ENSG00000185532	-0.04843247488729374	[1575]	[3224]	0	hSpCas9	negative selection	2286528
51153233	51153256	10	-	24336569	HL60	viability	ACATACAATCCACAATCTCCTGG	PRKG1	ENSG00000185532	0.8005881887063088	[620]	[2288]	6	hSpCas9	negative selection	2286529
51153239	51153262	10	+	24336569	HL60	viability	GATTGTGGATTGTATGTACCCGG	PRKG1	ENSG00000185532	0.3754118131046442	[564]	[1550]	3	hSpCas9	negative selection	2286530
51153249	51153272	10	+	24336569	HL60	viability	TGTATGTACCCGGTGGAGTATGG	PRKG1	ENSG00000185532	-1.6772798124341837	[466]	[308]	-9	hSpCas9	negative selection	2286531
51153149	51153172	10	+	24336569	KBM7	viability	CCTCTCTTGCCATAGGTCCAAGG	PRKG1	ENSG00000185532	0.04704656746782376	[1004]	[2831]	0	hSpCas9	negative selection	2353699
51153161	51153184	10	+	24336569	KBM7	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	1.1894953366915642	[144]	[901]	8	hSpCas9	negative selection	2353700
51153166	51153189	10	-	24336569	KBM7	viability	AGCTTCCTTTATAAGATCCTTGG	PRKG1	ENSG00000185532	0.3622808399441819	[410]	[1440]	3	hSpCas9	negative selection	2353701
51153191	51153214	10	-	24336569	KBM7	viability	TCTTCATAAAGTCATTGTCAAGG	PRKG1	ENSG00000185532	-0.44261294365553294	[434]	[872]	-4	hSpCas9	negative selection	2353702
51153197	51153220	10	+	24336569	KBM7	viability	CAATGACTTTATGAAGAACTTGG	PRKG1	ENSG00000185532	1.1104880771092132	[378]	[2231]	8	hSpCas9	negative selection	2353703
51153215	51153238	10	+	24336569	KBM7	viability	CTTGGAGCTGTCGCAGATCCAGG	PRKG1	ENSG00000185532	-0.3773856077583735	[350]	[736]	-3	hSpCas9	negative selection	2353704
51153224	51153247	10	+	24336569	KBM7	viability	GTCGCAGATCCAGGAGATTGTGG	PRKG1	ENSG00000185532	0.31607034576230886	[990]	[3364]	3	hSpCas9	negative selection	2353705
51153233	51153256	10	-	24336569	KBM7	viability	ACATACAATCCACAATCTCCTGG	PRKG1	ENSG00000185532	-0.12240463064086582	[798]	[2001]	-1	hSpCas9	negative selection	2353706
51153239	51153262	10	+	24336569	KBM7	viability	GATTGTGGATTGTATGTACCCGG	PRKG1	ENSG00000185532	0.45370275250122527	[377]	[1411]	4	hSpCas9	negative selection	2353707
51153249	51153272	10	+	24336569	KBM7	viability	TGTATGTACCCGGTGGAGTATGG	PRKG1	ENSG00000185532	0.3952164604214581	[246]	[885]	3	hSpCas9	negative selection	2353708
51276094	51276117	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAGGGGAGGGATAGCATTAAG	PRKG1	ENSG00000185532	2.1256450127545365	[23,13]	[18,16]	7	dCas9-VP64	positive selection	2394392
51398401	51398424	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGCTCACCTCCTGCTGTGTGG	PRKG1	ENSG00000185532	-0.7559545721697025	[264,101]	[18,27]	-4	dCas9-VP64	positive selection	2406599
51760835	51760858	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATCAGCCACCACACCAGG	PRKG1	ENSG00000185532	3.13947332771205	[140,99]	[396,56]	8	dCas9-VP64	positive selection	2409179
51164024	51164047	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	AACAGCTTTGAAGAGAGCAGTGG	PRKG1	ENSG00000185532	1.4119664675059675	[42,72]	[55,9]	5	dCas9-VP64	positive selection	2419350
51163955	51163978	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGTCTGTGCCCTGCCCCCAGAAG	PRKG1	ENSG00000185532	1.497238966706477	[157,415]	[28,341]	5	dCas9-VP64	positive selection	2421820
51716795	51716818	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGGCTGAGGCAGGAGAAGAG	PRKG1	ENSG00000185532	-0.8896445471743792	[26,0]	[0,0]	-5	dCas9-VP64	positive selection	2422219
51327364	51327387	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTACAGTGGTGCGATCCTGG	PRKG1	ENSG00000185532	0.022145587563181746	[17,17]	[3,2]	0	dCas9-VP64	positive selection	2432073
51104915	51104938	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGATGGGTTTTCACCATGTAGG	PRKG1	ENSG00000185532	3.916189069033361	[314,93]	[113,1282]	9	dCas9-VP64	positive selection	2433956
52225411	52225434	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGATTTTCTCCCACTCTGTAGG	PRKG1	ENSG00000185532	0.7639152657766295	[238,367]	[87,141]	3	dCas9-VP64	positive selection	2436042
51074314	51074337	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGTCTCAGGTTTAATCCCGGG	PRKG1	ENSG00000185532	-1.200902851449594	[48,73]	[7,2]	-7	dCas9-VP64	positive selection	2439752
51074332	51074355	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAAACCAGCAGGTCCAACCCGG	PRKG1	ENSG00000185532	0.24300983421228395	[277,799]	[90,195]	1	dCas9-VP64	positive selection	2439753
51074360	51074383	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGGCTGTGAGGCTCAGAGCGG	PRKG1	ENSG00000185532	-0.6617468444780139	[51,0]	[3,1]	-3	dCas9-VP64	positive selection	2439754
51743051	51743074	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAAGAGAGAGAGAGAGAGAAAGG	PRKG1	ENSG00000185532	0.6316515901792452	[28,11]	[9,2]	2	dCas9-VP64	positive selection	2441198
51699698	51699721	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATAAGTTGTTAGTGGGATGCAGG	PRKG1	ENSG00000185532	1.5092267703818745	[54,132]	[76,39]	5	dCas9-VP64	positive selection	2445429
51699673	51699696	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGAATCGTTCCGCTTGCCTGTGG	PRKG1	ENSG00000185532	1.8904078452611572	[27,158]	[58,96]	6	dCas9-VP64	positive selection	2445430
51699728	51699751	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCAGTCCCTGATCCTTCATGG	PRKG1	ENSG00000185532	-0.7638760363651282	[350,241]	[42,32]	-4	dCas9-VP64	positive selection	2445431
52132854	52132877	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	TACATGAGATGTTTTGATACAGG	PRKG1	ENSG00000185532	-0.1286182634042458	[83,58]	[15,11]	0	dCas9-VP64	positive selection	2457032
51045394	51045417	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCCACTTCCTGG	PRKG1	ENSG00000185532	-0.2161485283045399	[306,330]	[36,85]	-1	dCas9-VP64	positive selection	2459302
51604883	51604906	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGACCCTCTGCCTTATTGCAAGG	PRKG1	ENSG00000185532	2.512441324637357	[295,222]	[135,529]	8	dCas9-VP64	positive selection	2463899
51350998	51351021	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTGAGAACATGTGGTGTTCGG	PRKG1	ENSG00000185532	-1.1334071955764224	[258,107]	[23,10]	-6	dCas9-VP64	positive selection	2468905
51653122	51653145	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTAGGTTGATTCCATATCTTAG	PRKG1	ENSG00000185532	-0.8883757219304182	[55,162]	[4,20]	-5	dCas9-VP64	positive selection	2471639
51325369	51325392	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGTATTTTTAGTAGAGACGCAG	PRKG1	ENSG00000185532	4.010018042841921	[201,101]	[623,445]	9	dCas9-VP64	positive selection	2473514
51730028	51730051	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGAACCCTAATGTAAACTATGG	PRKG1	ENSG00000185532	2.1753413683523957	[31,17]	[14,35]	7	dCas9-VP64	positive selection	2477073
51012103	51012126	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTACAATTCAAGATGAGATTGGG	PRKG1	ENSG00000185532	-2.0010020361462013	[696,629]	[34,36]	-9	dCas9-VP64	positive selection	2478172
51276094	51276117	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAGGGGAGGGATAGCATTAAG	PRKG1	ENSG00000185532	-0.41439363160167897	[9,74]	[9,9]	-4	dCas9-VP64	positive selection	2489647
51398401	51398424	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGCTCACCTCCTGCTGTGTGG	PRKG1	ENSG00000185532	-0.3964671306337958	[317,78]	[58,39]	-4	dCas9-VP64	positive selection	2501854
51760835	51760858	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATCAGCCACCACACCAGG	PRKG1	ENSG00000185532	2.698989317197104	[135,124]	[110,433]	9	dCas9-VP64	positive selection	2504434
51164024	51164047	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	AACAGCTTTGAAGAGAGCAGTGG	PRKG1	ENSG00000185532	0.16626641655658703	[158,210]	[64,69]	1	dCas9-VP64	positive selection	2514605
51163955	51163978	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGTCTGTGCCCTGCCCCCAGAAG	PRKG1	ENSG00000185532	0.4115609227963175	[502,333]	[189,175]	3	dCas9-VP64	positive selection	2517075
51716795	51716818	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGGCTGAGGCAGGAGAAGAG	PRKG1	ENSG00000185532	0.4958448470370793	[21,20]	[10,7]	4	dCas9-VP64	positive selection	2517474
51327364	51327387	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTACAGTGGTGCGATCCTGG	PRKG1	ENSG00000185532	-0.8807468495272488	[128,53]	[16,14]	-8	dCas9-VP64	positive selection	2527328
51104915	51104938	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGATGGGTTTTCACCATGTAGG	PRKG1	ENSG00000185532	2.0642303287003654	[37,60]	[95,40]	8	dCas9-VP64	positive selection	2529211
52225411	52225434	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGATTTTCTCCCACTCTGTAGG	PRKG1	ENSG00000185532	0.5236801886781008	[591,391]	[147,310]	4	dCas9-VP64	positive selection	2531297
51074314	51074337	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGTCTCAGGTTTAATCCCGGG	PRKG1	ENSG00000185532	-0.5861618198346025	[94,88]	[24,13]	-6	dCas9-VP64	positive selection	2535007
51074332	51074355	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAAACCAGCAGGTCCAACCCGG	PRKG1	ENSG00000185532	-0.21374900799280327	[457,318]	[85,131]	-2	dCas9-VP64	positive selection	2535008
51074360	51074383	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGGCTGTGAGGCTCAGAGCGG	PRKG1	ENSG00000185532	-1.3620126599514146	[127,12]	[4,11]	-9	dCas9-VP64	positive selection	2535009
51743051	51743074	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAAGAGAGAGAGAGAGAGAAAGG	PRKG1	ENSG00000185532	0.43533825533627796	[75,43]	[28,22]	3	dCas9-VP64	positive selection	2536453
51699698	51699721	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATAAGTTGTTAGTGGGATGCAGG	PRKG1	ENSG00000185532	0.394491109820881	[67,111]	[19,54]	3	dCas9-VP64	positive selection	2540684
51699673	51699696	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGAATCGTTCCGCTTGCCTGTGG	PRKG1	ENSG00000185532	-0.5513070069364544	[228,279]	[55,56]	-5	dCas9-VP64	positive selection	2540685
51699728	51699751	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCAGTCCCTGATCCTTCATGG	PRKG1	ENSG00000185532	0.5013006605971096	[320,116]	[179,28]	4	dCas9-VP64	positive selection	2540686
52132854	52132877	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	TACATGAGATGTTTTGATACAGG	PRKG1	ENSG00000185532	0.792046020519842	[120,109]	[48,80]	5	dCas9-VP64	positive selection	2552287
51045394	51045417	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCCACTTCCTGG	PRKG1	ENSG00000185532	0.9402930649503107	[330,263]	[213,160]	6	dCas9-VP64	positive selection	2554557
51604883	51604906	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGACCCTCTGCCTTATTGCAAGG	PRKG1	ENSG00000185532	0.5912507813641084	[407,301]	[248,105]	4	dCas9-VP64	positive selection	2559154
51350998	51351021	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTGAGAACATGTGGTGTTCGG	PRKG1	ENSG00000185532	-0.007859909983208867	[140,86]	[47,26]	0	dCas9-VP64	positive selection	2564160
51653122	51653145	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTAGGTTGATTCCATATCTTAG	PRKG1	ENSG00000185532	-0.1306876359303103	[167,77]	[46,26]	-1	dCas9-VP64	positive selection	2566894
51325369	51325392	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGTATTTTTAGTAGAGACGCAG	PRKG1	ENSG00000185532	1.087060795387326	[282,711]	[216,460]	7	dCas9-VP64	positive selection	2568769
51730028	51730051	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGAACCCTAATGTAAACTATGG	PRKG1	ENSG00000185532	-0.495963684238195	[290,79]	[45,39]	-5	dCas9-VP64	positive selection	2572328
51012103	51012126	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTACAATTCAAGATGAGATTGGG	PRKG1	ENSG00000185532	-0.023705952056314983	[265,419]	[72,143]	0	dCas9-VP64	positive selection	2573427
50991493	50991516	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAAACTCCACAAATGCCAGTCGG	PRKG1	ENSG00000185532	0.3293851898496801	[4,4]	[5,4]	7	hSpCas9	positive selection	3013705
50991624	50991647	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAAGTTCACCAAGTCCGAAAGG	PRKG1	ENSG00000185532	-0.14501083395437725	[2,2]	[2,1]	-2	hSpCas9	positive selection	3013706
50991609	50991632	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAACTTCCGGAATGCCTGTCGG	PRKG1	ENSG00000185532	-0.04016483537050669	[5,4]	[5,2]	0	hSpCas9	positive selection	3013707
52054510	52054533	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	-0.12175848616653978	[4,4]	[4,2]	-2	hSpCas9	positive selection	3013708
50991493	50991516	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAAACTCCACAAATGCCAGTCGG	PRKG1	ENSG00000185532	0.19206524835514394	[4,4]	[3,3]	3	hSpCas9	positive selection	3081563
50991624	50991647	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAAGTTCACCAAGTCCGAAAGG	PRKG1	ENSG00000185532	-0.5140003485175709	[2,2]	[1,0]	-7	hSpCas9	positive selection	3081564
50991609	50991632	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAACTTCCGGAATGCCTGTCGG	PRKG1	ENSG00000185532	0.19127773013132016	[5,5]	[4,3]	3	hSpCas9	positive selection	3081565
52054510	52054533	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.016509780880927277	[4,4]	[1,3]	0	hSpCas9	positive selection	3081566
51467817	51467840		-	24336571	A375	resistance to PLX after 7 days	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.015300747010809967	[43,47]	[44,47]	0	hSpCas9	positive selection	3137839
51153161	51153184		+	24336571	A375	resistance to PLX after 7 days	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.07230654206682408	[21,24]	[27,20]	2	hSpCas9	positive selection	3137840
51467817	51467840		-	24336571	A375	resistance to PLX after 14 days	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	-0.3267220366337511	[50,40]	[15,17]	-4	hSpCas9	positive selection	3195632
51153161	51153184		+	24336571	A375	resistance to PLX after 14 days	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.8208136470218522	[13,21]	[14,13]	7	hSpCas9	positive selection	3195633
51467817	51467840		-	24336571	A375	viability after 7 days	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.45594803751878055	[34]	[43,47]	7	hSpCas9	negative selection	3253425
51153161	51153184		+	24336571	A375	viability after 7 days	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.21558325212359342	[28]	[21,24]	-3	hSpCas9	negative selection	3253426
51467817	51467840		-	24336571	A375	viability after 14 days	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.4664711942614681	[34]	[50,40]	6	hSpCas9	negative selection	3311218
51153161	51153184		+	24336571	A375	viability after 14 days	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.5767068047825575	[28]	[13,21]	-6	hSpCas9	negative selection	3311219
51467755	51467778	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.6279695913662254	[197,197]	[1,1]	3	hSpCas9	positive selection	3387519
51153258	51153281	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	4.393828211350697	[392,392]	[53,53]	9	hSpCas9	positive selection	3387520
51804609	51804632	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.7815927804794374	[88,88]	[0,0]	4	hSpCas9	positive selection	3387521
50991492	50991515	10	+	26780180	HT29	viability (Avana library 4 designs)	GAAACTCCACAAATGCCAGTCGG	PRKG1	ENSG00000185532	-0.544529372460887	[]	[]	-7	hSpCas9	negative selection	3451896
50991623	50991646	10	+	26780180	HT29	viability (Avana library 4 designs)	GGAAGTTCACCAAGTCCGAAAGG	PRKG1	ENSG00000185532	1.83014212073152	[]	[]	7	hSpCas9	negative selection	3451897
50991609	50991632	10	-	26780180	HT29	viability (Avana library 4 designs)	TGAACTTCCGGAATGCCTGTCGG	PRKG1	ENSG00000185532	0.315402627611449	[]	[]	1	hSpCas9	negative selection	3451898
52054509	52054532	10	+	26780180	HT29	viability (Avana library 4 designs)	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.331053041227051	[]	[]	1	hSpCas9	negative selection	3451899
50991623	50991646	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAAGTTCACCAAGTCCGAAAGG	PRKG1	ENSG00000185532	0.0455965394492117	[]	[]	0	hSpCas9	negative selection	3548008
50991609	50991632	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAACTTCCGGAATGCCTGTCGG	PRKG1	ENSG00000185532	3.52379428328932	[]	[]	5	hSpCas9	negative selection	3548009
50991492	50991515	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAAACTCCACAAATGCCAGTCGG	PRKG1	ENSG00000185532	0.26239204502192	[]	[]	0	hSpCas9	negative selection	3548010
52054509	52054532	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	-2.11313315786227	[]	[]	-3	hSpCas9	negative selection	3548011
51153242	51153265	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	1.32461704347156	[]	[]	1	hSpCas9	negative selection	3548012
50991606	50991629	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTTCCGGAATGCCTGTCGGAGG	PRKG1	ENSG00000185532	6.79003054113786	[]	[]	9	hSpCas9	negative selection	3548013
50991623	50991646	10	+	26780180	A375	viability (Avana lentiGuide)	GGAAGTTCACCAAGTCCGAAAGG	PRKG1	ENSG00000185532	-3.9087261079277	[]	[]	-6	hSpCas9	negative selection	3656667
50991609	50991632	10	-	26780180	A375	viability (Avana lentiGuide)	TGAACTTCCGGAATGCCTGTCGG	PRKG1	ENSG00000185532	-0.0676254518222143	[]	[]	0	hSpCas9	negative selection	3656668
50991492	50991515	10	+	26780180	A375	viability (Avana lentiGuide)	GAAACTCCACAAATGCCAGTCGG	PRKG1	ENSG00000185532	-1.834003804639	[]	[]	-3	hSpCas9	negative selection	3656669
52054509	52054532	10	+	26780180	A375	viability (Avana lentiGuide)	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	-5.62542988823277	[]	[]	-8	hSpCas9	negative selection	3656670
51153242	51153265	10	+	26780180	A375	viability (Avana lentiGuide)	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	-0.422999523682195	[]	[]	0	hSpCas9	negative selection	3656671
50991606	50991629	10	-	26780180	A375	viability (Avana lentiGuide)	ACTTCCGGAATGCCTGTCGGAGG	PRKG1	ENSG00000185532	-1.47468024702943	[]	[]	-2	hSpCas9	negative selection	3656672
50991623	50991646	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAAGTTCACCAAGTCCGAAAGG	PRKG1	ENSG00000185532	-0.4144901741773346	[4]	[3,2]	-6	hSpCas9	positive selection	3765274
50991609	50991632	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAACTTCCGGAATGCCTGTCGG	PRKG1	ENSG00000185532	0.04106092531785038	[6]	[6,5]	1	hSpCas9	positive selection	3765275
50991492	50991515	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAACTCCACAAATGCCAGTCGG	PRKG1	ENSG00000185532	-0.040114860777155634	[5]	[5,4]	0	hSpCas9	positive selection	3765276
52054509	52054532	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	-0.0907148522844424	[6]	[5,5]	-1	hSpCas9	positive selection	3765277
51153242	51153265	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.26345483660256325	[4]	[6,5]	7	hSpCas9	positive selection	3765278
50991606	50991629	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTTCCGGAATGCCTGTCGGAGG	PRKG1	ENSG00000185532	0.39875479688906185	[4]	[6,5]	9	hSpCas9	positive selection	3765279
50991623	50991646	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAAGTTCACCAAGTCCGAAAGG	PRKG1	ENSG00000185532	-0.17866960316303748	[3]	[2,2]	-2	hSpCas9	positive selection	3873881
50991609	50991632	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAACTTCCGGAATGCCTGTCGG	PRKG1	ENSG00000185532	0.12779344477196136	[7]	[6,5]	3	hSpCas9	positive selection	3873882
50991492	50991515	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAACTCCACAAATGCCAGTCGG	PRKG1	ENSG00000185532	0.21328583441972532	[6]	[6,6]	5	hSpCas9	positive selection	3873883
52054509	52054532	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.32525421234413554	[5]	[6,6]	8	hSpCas9	positive selection	3873884
51153242	51153265	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.11018559844465173	[5]	[4,5]	2	hSpCas9	positive selection	3873885
50991606	50991629	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTTCCGGAATGCCTGTCGGAGG	PRKG1	ENSG00000185532	0.306636589949835	[5]	[5,5]	8	hSpCas9	positive selection	3873886
51467755	51467778	10	+	26780180	A375	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	1.38775826874406	[]	[]	7	hSpCas9	negative selection	3984342
51804655	51804678	10	+	26780180	A375	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	1.13930874068503	[]	[]	6	hSpCas9	negative selection	3984343
51153258	51153281	10	-	26780180	A375	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.696223122422485	[]	[]	2	hSpCas9	negative selection	3984344
51467817	51467840	10	-	26780180	A375	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.59142309028571	[]	[]	1	hSpCas9	negative selection	3984345
51153161	51153184	10	+	26780180	A375	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.782272092773993	[]	[]	3	hSpCas9	negative selection	3984346
51804609	51804632	10	-	26780180	A375	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.632432868300329	[]	[]	2	hSpCas9	negative selection	3984347
51467755	51467778	10	+	26780180	HT29	viability (GeCKOv2 library)	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	1.68044378684475	[]	[]	8	hSpCas9	negative selection	4092308
51804655	51804678	10	+	26780180	HT29	viability (GeCKOv2 library)	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.0910164403217928	[]	[]	0	hSpCas9	negative selection	4092309
51153258	51153281	10	-	26780180	HT29	viability (GeCKOv2 library)	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	1.10109082273588	[]	[]	5	hSpCas9	negative selection	4092310
51467817	51467840	10	-	26780180	HT29	viability (GeCKOv2 library)	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.60861640801986	[]	[]	2	hSpCas9	negative selection	4092311
51153161	51153184	10	+	26780180	HT29	viability (GeCKOv2 library)	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.839140100872389	[]	[]	3	hSpCas9	negative selection	4092312
51804609	51804632	10	-	26780180	HT29	viability (GeCKOv2 library)	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	1.23073308674891	[]	[]	6	hSpCas9	negative selection	4092313
51467817	51467840	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.14853802272214167	[5]	[4,4]	4	hSpCas9	positive selection	4163000
51153161	51153184	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.2512319292976204	[4]	[3,3]	6	hSpCas9	positive selection	4163001
51467817	51467840	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	1.201116983356225	[4]	[6,2,4,4]	8	hSpCas9	positive selection	4227022
51153161	51153184	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.32478478996827326	[4]	[1,3,1,0]	-5	hSpCas9	positive selection	4227023
51467817	51467840	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.24835394053975463	[4]	[4,3]	5	hSpCas9	positive selection	4292213
51804655	51804678	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.19404624742593837	[2]	[3,1]	4	hSpCas9	positive selection	4292214
51153161	51153184	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.23154852403100706	[2]	[3,1]	4	hSpCas9	positive selection	4292215
52049812	52049835	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.01889883644359358	[5]	[4,3]	0	hSpCas9	positive selection	4312117
52049812	52049835	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.01889883644359358	[5]	[4,3]	0	hSpCas9	positive selection	4312121
51467755	51467778	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.0036478427337620287	[3]	[4,0]	0	hSpCas9	positive selection	4356471
51153258	51153281	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	-0.03059107921196383	[3]	[3,2]	0	hSpCas9	positive selection	4356472
51804609	51804632	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.26717238564543555	[2]	[2,1]	5	hSpCas9	positive selection	4356473
51153243	51153265	10	+	27760321	OCIAML3	viability	GTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.4479367600554679	[466,395]	[377,563]	5	hSpCas9	negative selection	4430661
51467756	51467778	10	+	27760321	OCIAML3	viability	AGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.628367345217767	[844,802]	[956,1049]	7	hSpCas9	negative selection	4430662
51467799	51467821	10	+	27760321	OCIAML3	viability	TATTCTTTACAACTGTACCCGG	PRKG1	ENSG00000185532	2.165266378151706	[13,14]	[25,83]	9	hSpCas9	negative selection	4430663
52133888	52133910	10	-	27760321	OCIAML3	viability	TTACTCTCTGTCAATCACAAGG	PRKG1	ENSG00000185532	0.7759740320017194	[167,153]	[205,227]	8	hSpCas9	negative selection	4430664
51153243	51153265	10	+	27760321	OCIAML2	viability	GTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.2320712196288165	[466,395]	[367,461]	3	hSpCas9	negative selection	4514124
51467756	51467778	10	+	27760321	OCIAML2	viability	AGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.5250185809791036	[844,802]	[870,1077]	7	hSpCas9	negative selection	4514125
51467799	51467821	10	+	27760321	OCIAML2	viability	TATTCTTTACAACTGTACCCGG	PRKG1	ENSG00000185532	0.17634388079638352	[13,14]	[5,22]	2	hSpCas9	negative selection	4514126
52133888	52133910	10	-	27760321	OCIAML2	viability	TTACTCTCTGTCAATCACAAGG	PRKG1	ENSG00000185532	0.2647365223642082	[167,153]	[155,156]	3	hSpCas9	negative selection	4514127
51153243	51153265	10	+	27760321	MV411	viability	GTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.6188916385767184	[466,395]	[396,493]	4	hSpCas9	negative selection	4597587
51467756	51467778	10	+	27760321	MV411	viability	AGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.4411586256322261	[844,802]	[663,851]	3	hSpCas9	negative selection	4597588
51467799	51467821	10	+	27760321	MV411	viability	TATTCTTTACAACTGTACCCGG	PRKG1	ENSG00000185532	-3.267097062469018	[13,14]	[0,0]	-9	hSpCas9	negative selection	4597589
52133888	52133910	10	-	27760321	MV411	viability	TTACTCTCTGTCAATCACAAGG	PRKG1	ENSG00000185532	-1.332597460592104	[167,153]	[8,91]	-7	hSpCas9	negative selection	4597590
51153243	51153265	10	+	27760321	HL60	viability	GTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.9138096505460486	[466,395]	[670,651]	8	hSpCas9	negative selection	4681050
51467756	51467778	10	+	27760321	HL60	viability	AGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.43187843217148913	[844,802]	[729,1098]	5	hSpCas9	negative selection	4681051
51467799	51467821	10	+	27760321	HL60	viability	TATTCTTTACAACTGTACCCGG	PRKG1	ENSG00000185532	-3.5749672242631547	[13,14]	[0,0]	-9	hSpCas9	negative selection	4681052
52133888	52133910	10	-	27760321	HL60	viability	TTACTCTCTGTCAATCACAAGG	PRKG1	ENSG00000185532	0.059202621317141935	[167,153]	[119,154]	0	hSpCas9	negative selection	4681053
51153243	51153265	10	+	27760321	HT1080	viability	GTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	1.3457419234518446	[395,308]	[533,162]	7	hSpCas9	negative selection	4764513
51467756	51467778	10	+	27760321	HT1080	viability	AGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.9335411105234758	[802,626]	[723,346]	5	hSpCas9	negative selection	4764514
51467799	51467821	10	+	27760321	HT1080	viability	TATTCTTTACAACTGTACCCGG	PRKG1	ENSG00000185532	-2.429279739642115	[14,11]	[0,0]	-7	hSpCas9	negative selection	4764515
52133888	52133910	10	-	27760321	HT1080	viability	TTACTCTCTGTCAATCACAAGG	PRKG1	ENSG00000185532	0.4612237220897548	[153,119]	[119,25]	2	hSpCas9	negative selection	4764516
51153243	51153265	10	+	27760321	HT29	viability after 7 days	GTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.1141451841758292	[395,308]	[720,332,450]	1	hSpCas9	negative selection	4847976
51467756	51467778	10	+	27760321	HT29	viability after 7 days	AGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.03463188255249605	[802,626]	[1051,914,750]	0	hSpCas9	negative selection	4847977
51467799	51467821	10	+	27760321	HT29	viability after 7 days	TATTCTTTACAACTGTACCCGG	PRKG1	ENSG00000185532	-4.118939993191379	[14,11]	[0,0,0]	-9	hSpCas9	negative selection	4847978
52133888	52133910	10	-	27760321	HT29	viability after 7 days	TTACTCTCTGTCAATCACAAGG	PRKG1	ENSG00000185532	0.014575515741451328	[153,119]	[148,190,188]	0	hSpCas9	negative selection	4847979
51153243	51153265	10	+	27760321	HT29	viability after 25 days	GTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.03298812947377746	[395,308]	[432,393,406]	0	hSpCas9	negative selection	4931439
51467756	51467778	10	+	27760321	HT29	viability after 25 days	AGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.057523070379925545	[802,626]	[692,798,1092]	0	hSpCas9	negative selection	4931440
51467799	51467821	10	+	27760321	HT29	viability after 25 days	TATTCTTTACAACTGTACCCGG	PRKG1	ENSG00000185532	-3.9489620044886387	[14,11]	[0,0,0]	-9	hSpCas9	negative selection	4931441
52133888	52133910	10	-	27760321	HT29	viability after 25 days	TTACTCTCTGTCAATCACAAGG	PRKG1	ENSG00000185532	0.128122351203799	[153,119]	[136,285,82]	1	hSpCas9	negative selection	4931442
51153243	51153265	10	+	27760321	HT29	viability after 22 days	GTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.18998912940857163	[395,308]	[235,568,596]	2	hSpCas9	negative selection	5014902
51467756	51467778	10	+	27760321	HT29	viability after 22 days	AGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.06959578796862576	[802,626]	[813,683,864]	0	hSpCas9	negative selection	5014903
51467799	51467821	10	+	27760321	HT29	viability after 22 days	TATTCTTTACAACTGTACCCGG	PRKG1	ENSG00000185532	-1.2453724366193457	[14,11]	[0,4,13]	-7	hSpCas9	negative selection	5014904
52133888	52133910	10	-	27760321	HT29	viability after 22 days	TTACTCTCTGTCAATCACAAGG	PRKG1	ENSG00000185532	-1.122521149288313	[153,119]	[20,83,114]	-7	hSpCas9	negative selection	5014905
51153243	51153265	10	+	27760321	HT29	viability after 19 days	GTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.38488173343960597	[395,308]	[388,716,460]	4	hSpCas9	negative selection	5098365
51467756	51467778	10	+	27760321	HT29	viability after 19 days	AGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.3640688546405585	[802,626]	[1136,852,1170]	3	hSpCas9	negative selection	5098366
51467799	51467821	10	+	27760321	HT29	viability after 19 days	TATTCTTTACAACTGTACCCGG	PRKG1	ENSG00000185532	-3.950440583924685	[14,11]	[0,0,0]	-9	hSpCas9	negative selection	5098367
52133888	52133910	10	-	27760321	HT29	viability after 19 days	TTACTCTCTGTCAATCACAAGG	PRKG1	ENSG00000185532	-0.010220353766318357	[153,119]	[112,82,261]	0	hSpCas9	negative selection	5098368
51153243	51153265	10	+	27760321	HT29	viability after 16 days	GTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	-0.003710747839083345	[395,308]	[476,351,359]	0	hSpCas9	negative selection	5181828
51467756	51467778	10	+	27760321	HT29	viability after 16 days	AGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.040294211543829395	[802,626]	[901,639,806]	0	hSpCas9	negative selection	5181829
51467799	51467821	10	+	27760321	HT29	viability after 16 days	TATTCTTTACAACTGTACCCGG	PRKG1	ENSG00000185532	0.3701683254203445	[14,11]	[0,53,0]	4	hSpCas9	negative selection	5181830
52133888	52133910	10	-	27760321	HT29	viability after 16 days	TTACTCTCTGTCAATCACAAGG	PRKG1	ENSG00000185532	-0.27997530748699373	[153,119]	[88,169,114]	-3	hSpCas9	negative selection	5181831
51153243	51153265	10	+	27760321	HT29	viability after 13 days	GTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	-0.07257189675683448	[395,308]	[246,447,466]	-1	hSpCas9	negative selection	5265291
51467756	51467778	10	+	27760321	HT29	viability after 13 days	AGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.28429230326320376	[802,626]	[1176,928,928]	3	hSpCas9	negative selection	5265292
51467799	51467821	10	+	27760321	HT29	viability after 13 days	TATTCTTTACAACTGTACCCGG	PRKG1	ENSG00000185532	-1.5101778063883868	[14,11]	[0,0,13]	-8	hSpCas9	negative selection	5265293
52133888	52133910	10	-	27760321	HT29	viability after 13 days	TTACTCTCTGTCAATCACAAGG	PRKG1	ENSG00000185532	-0.42961950733323717	[153,119]	[41,208,103]	-5	hSpCas9	negative selection	5265294
51153243	51153265	10	+	27760321	HT29	viability after 10 days	GTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.027635653994522242	[395,308]	[467,383,490]	0	hSpCas9	negative selection	5348754
51467756	51467778	10	+	27760321	HT29	viability after 10 days	AGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.1449794654279165	[802,626]	[986,565,860]	-2	hSpCas9	negative selection	5348755
51467799	51467821	10	+	27760321	HT29	viability after 10 days	TATTCTTTACAACTGTACCCGG	PRKG1	ENSG00000185532	-1.6065560969922466	[14,11]	[0,14,0]	-8	hSpCas9	negative selection	5348756
52133888	52133910	10	-	27760321	HT29	viability after 10 days	TTACTCTCTGTCAATCACAAGG	PRKG1	ENSG00000185532	-0.6497136132047461	[153,119]	[131,117,77]	-6	hSpCas9	negative selection	5348757
51153243	51153265	10	+	27760321	MOLM13	viability	GTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.42670498213466845	[466,395]	[391,269]	3	hSpCas9	negative selection	5432217
51467756	51467778	10	+	27760321	MOLM13	viability	AGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.2189897829566433	[844,802]	[333,455]	-1	hSpCas9	negative selection	5432218
51467799	51467821	10	+	27760321	MOLM13	viability	TATTCTTTACAACTGTACCCGG	PRKG1	ENSG00000185532	-3.041040249641423	[13,14]	[0,0]	-9	hSpCas9	negative selection	5432219
52133888	52133910	10	-	27760321	MOLM13	viability	TTACTCTCTGTCAATCACAAGG	PRKG1	ENSG00000185532	1.0685270812740209	[167,153]	[412,0]	7	hSpCas9	negative selection	5432220
50991423	50991446	10	+	27661255	K562	viability	GGAGGAGAGGATCAAAGAGCTGG	PRKG1	ENSG00000185532	0.11398436807147808	[607,752]	[693,493]	4	dCas9-KRAB	negative selection	5504201
50991533	50991556	10	-	27661255	K562	viability	GGTGGTCCGGGGGCCGATGTGGG	PRKG1	ENSG00000185532	-0.013949709300885571	[687,615]	[579,462]	0	dCas9-KRAB	negative selection	5504202
51467817	51467840	10	-	27260156	BXPC3	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	-0.03576777564285982	[1230]	[1131,1242,1343,1317]	-1	hSpCas9	negative selection	5564673
51804655	51804678	10	+	27260156	BXPC3	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.24893264925379066	[307]	[291,322,385,562]	5	hSpCas9	negative selection	5564674
51153161	51153184	10	+	27260156	BXPC3	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.004081323935366421	[235]	[291,165,230,305]	0	hSpCas9	negative selection	5564675
52049812	52049835	10	+	27260156	BXPC3	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.10492013047121196	[2362]	[2248,2672,2625,3167]	2	hSpCas9	negative selection	5584577
52049812	52049835	10	+	27260156	BXPC3	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.10492013047121196	[2362]	[2248,2672,2625,3167]	2	hSpCas9	negative selection	5584581
51467755	51467778	10	+	27260156	BXPC3	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.03555543006035252	[496]	[538,519,527,422]	-1	hSpCas9	negative selection	5628931
51153258	51153281	10	-	27260156	BXPC3	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.23543960753727744	[870]	[1091,989,986,1232]	5	hSpCas9	negative selection	5628932
51804609	51804632	10	-	27260156	BXPC3	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.16371140726571398	[229]	[231,201,330,326]	3	hSpCas9	negative selection	5628933
51467817	51467840	10	-	27260156	A673	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.08286451346444457	[1230]	[1824,1506,1347,1614]	2	hSpCas9	negative selection	5685924
51804655	51804678	10	+	27260156	A673	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.15641281676566576	[307]	[437,319,476,417]	4	hSpCas9	negative selection	5685925
51153161	51153184	10	+	27260156	A673	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.03666263886717003	[235]	[435,198,307,234]	0	hSpCas9	negative selection	5685926
52049812	52049835	10	+	27260156	A673	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.08469331155878734	[2362]	[3060,2803,2981,3204]	2	hSpCas9	negative selection	5705828
52049812	52049835	10	+	27260156	A673	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.08469331155878734	[2362]	[3060,2803,2981,3204]	2	hSpCas9	negative selection	5705832
51467755	51467778	10	+	27260156	A673	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.2958563298211169	[496]	[570,526,416,434]	-6	hSpCas9	negative selection	5750182
51153258	51153281	10	-	27260156	A673	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.183137833939642	[870]	[1413,1111,1083,1164]	4	hSpCas9	negative selection	5750183
51804609	51804632	10	-	27260156	A673	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	-0.020795441353292476	[229]	[353,250,261,228]	0	hSpCas9	negative selection	5750184
51467817	51467840	10	-	27260156	A375	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.28446016949103914	[1230]	[1684,2350,1683,1402]	4	hSpCas9	negative selection	5807175
51804655	51804678	10	+	27260156	A375	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.7350368502742388	[307]	[753,734,446,489]	9	hSpCas9	negative selection	5807176
51153161	51153184	10	+	27260156	A375	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.13421921733932984	[235]	[448,267,257,237]	2	hSpCas9	negative selection	5807177
52049812	52049835	10	+	27260156	A375	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	-0.09121942846519326	[2362]	[2625,2771,2724,2291]	-1	hSpCas9	negative selection	5827079
52049812	52049835	10	+	27260156	A375	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	-0.09121942846519326	[2362]	[2625,2771,2724,2291]	-1	hSpCas9	negative selection	5827083
51467755	51467778	10	+	27260156	A375	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.04636832920724589	[496]	[550,778,489,599]	0	hSpCas9	negative selection	5871433
51153258	51153281	10	-	27260156	A375	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.15938559068031866	[870]	[1028,1331,1266,959]	2	hSpCas9	negative selection	5871434
51804609	51804632	10	-	27260156	A375	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.2811552267604265	[229]	[235,268,391,390]	4	hSpCas9	negative selection	5871435
51467817	51467840	10	-	27260156	COLO741	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.22479728232716378	[1230]	[1950,1696,1868]	5	hSpCas9	negative selection	5928426
51804655	51804678	10	+	27260156	COLO741	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.1658569542246675	[307]	[467,462,397]	3	hSpCas9	negative selection	5928427
51153161	51153184	10	+	27260156	COLO741	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.09409221659755995	[235]	[315,297,238]	-2	hSpCas9	negative selection	5928428
52049812	52049835	10	+	27260156	COLO741	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.041379653164545616	[2362]	[3676,2808,2891]	0	hSpCas9	negative selection	5948330
52049812	52049835	10	+	27260156	COLO741	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.041379653164545616	[2362]	[3676,2808,2891]	0	hSpCas9	negative selection	5948334
51467755	51467778	10	+	27260156	COLO741	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.0597850097026698	[496]	[575,601,642]	-1	hSpCas9	negative selection	5992684
51153258	51153281	10	-	27260156	COLO741	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.039211748288083714	[870]	[1267,1188,992]	0	hSpCas9	negative selection	5992685
51804609	51804632	10	-	27260156	COLO741	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.16996704339891444	[229]	[376,315,303]	3	hSpCas9	negative selection	5992686
51467817	51467840	10	-	27260156	CAL120	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.10370349651512423	[1230]	[2075,1501,1427]	1	hSpCas9	negative selection	6049677
51804655	51804678	10	+	27260156	CAL120	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.12104481424281238	[307]	[639,346,298]	1	hSpCas9	negative selection	6049678
51153161	51153184	10	+	27260156	CAL120	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.12656300149523836	[235]	[321,229,262]	-2	hSpCas9	negative selection	6049679
52049812	52049835	10	+	27260156	CAL120	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.18488550286431682	[2362]	[4646,2709,2873]	2	hSpCas9	negative selection	6069581
52049812	52049835	10	+	27260156	CAL120	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.18488550286431682	[2362]	[4646,2709,2873]	2	hSpCas9	negative selection	6069585
51467755	51467778	10	+	27260156	CAL120	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.2742965103300106	[496]	[456,683,386]	-4	hSpCas9	negative selection	6113935
51153258	51153281	10	-	27260156	CAL120	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	-0.0552330620704945	[870]	[878,1331,895]	-1	hSpCas9	negative selection	6113936
51804609	51804632	10	-	27260156	CAL120	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.24232123547048146	[229]	[276,375,352]	3	hSpCas9	negative selection	6113937
51467817	51467840	10	-	27260156	CADOES1	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.30192867086720376	[1230]	[1235,1565,1240,1610]	5	hSpCas9	negative selection	6170928
51804655	51804678	10	+	27260156	CADOES1	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.4246850746344566	[307]	[399,344,252,545]	7	hSpCas9	negative selection	6170929
51153161	51153184	10	+	27260156	CADOES1	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.033598616358560984	[235]	[168,176,217,338]	0	hSpCas9	negative selection	6170930
52049812	52049835	10	+	27260156	CADOES1	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.05701063382462257	[2362]	[2053,2623,1941,2535]	1	hSpCas9	negative selection	6190832
52049812	52049835	10	+	27260156	CADOES1	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.05701063382462257	[2362]	[2053,2623,1941,2535]	1	hSpCas9	negative selection	6190836
51467755	51467778	10	+	27260156	CADOES1	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.1745280698046548	[496]	[469,616,428,572]	3	hSpCas9	negative selection	6235186
51153258	51153281	10	-	27260156	CADOES1	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.2642352603970676	[870]	[1071,987,843,987]	4	hSpCas9	negative selection	6235187
51804609	51804632	10	-	27260156	CADOES1	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.35051421418598405	[229]	[209,248,258,376]	6	hSpCas9	negative selection	6235188
51467817	51467840	10	-	27260156	EWS502	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.23449540878338304	[1230]	[1172,1701,1343,1976]	4	hSpCas9	negative selection	6292179
51804655	51804678	10	+	27260156	EWS502	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.27760265750077007	[307]	[305,392,443,452]	5	hSpCas9	negative selection	6292180
51153161	51153184	10	+	27260156	EWS502	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.23468761515290337	[235]	[272,224,406,275]	4	hSpCas9	negative selection	6292181
52049812	52049835	10	+	27260156	EWS502	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.12664596542385365	[2362]	[2386,2610,3214,2761]	2	hSpCas9	negative selection	6312083
52049812	52049835	10	+	27260156	EWS502	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.12664596542385365	[2362]	[2386,2610,3214,2761]	2	hSpCas9	negative selection	6312087
51467755	51467778	10	+	27260156	EWS502	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.1143865153629766	[496]	[397,474,579,503]	-2	hSpCas9	negative selection	6356437
51153258	51153281	10	-	27260156	EWS502	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.39058622878137206	[870]	[977,1174,1285,1440]	6	hSpCas9	negative selection	6356438
51804609	51804632	10	-	27260156	EWS502	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	-0.09513507787337261	[229]	[287,204,173,237]	-2	hSpCas9	negative selection	6356439
51467817	51467840	10	-	27260156	EW8	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.3008070447838711	[1230]	[1738,1108,890,1285]	5	hSpCas9	negative selection	6413430
51804655	51804678	10	+	27260156	EW8	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.20633880985106856	[307]	[210,277,367,271]	4	hSpCas9	negative selection	6413431
51153161	51153184	10	+	27260156	EW8	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.0010800727518405218	[235]	[270,198,136,174]	0	hSpCas9	negative selection	6413432
52049812	52049835	10	+	27260156	EW8	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.13333577198168012	[2362]	[2396,1993,2143,1885]	2	hSpCas9	negative selection	6433334
52049812	52049835	10	+	27260156	EW8	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.13333577198168012	[2362]	[2396,1993,2143,1885]	2	hSpCas9	negative selection	6433338
51467755	51467778	10	+	27260156	EW8	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.1559796203570572	[496]	[356,597,409,425]	3	hSpCas9	negative selection	6477688
51153258	51153281	10	-	27260156	EW8	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.11092386135037102	[870]	[635,908,616,895]	2	hSpCas9	negative selection	6477689
51804609	51804632	10	-	27260156	EW8	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	-0.19031130615782765	[229]	[186,116,134,220]	-4	hSpCas9	negative selection	6477690
51467817	51467840	10	-	27260156	CORL105	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.18274055804822353	[1230]	[1811,1545,1707,1495]	3	hSpCas9	negative selection	6534681
51804655	51804678	10	+	27260156	CORL105	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.3644921928196908	[307]	[477,316,729,376]	6	hSpCas9	negative selection	6534682
51153161	51153184	10	+	27260156	CORL105	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.29720152073913597	[235]	[250,264,560,313]	5	hSpCas9	negative selection	6534683
52049812	52049835	10	+	27260156	CORL105	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.026832224980422925	[2362]	[2941,2685,2781,2862]	0	hSpCas9	negative selection	6554585
52049812	52049835	10	+	27260156	CORL105	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.026832224980422925	[2362]	[2941,2685,2781,2862]	0	hSpCas9	negative selection	6554589
51467755	51467778	10	+	27260156	CORL105	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.06510122633336125	[496]	[613,663,621,535]	1	hSpCas9	negative selection	6598939
51153258	51153281	10	-	27260156	CORL105	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.04967307389601128	[870]	[1018,1143,1277,812]	0	hSpCas9	negative selection	6598940
51804609	51804632	10	-	27260156	CORL105	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	-0.07653945154645436	[229]	[254,258,278,231]	-1	hSpCas9	negative selection	6598941
51467817	51467840	10	-	27260156	HS294T	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.6534598871191677	[1230]	[585,914,488,1064]	8	hSpCas9	negative selection	6655932
51804655	51804678	10	+	27260156	HS294T	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.8241162535813173	[307]	[118,151,144,482]	9	hSpCas9	negative selection	6655933
51153161	51153184	10	+	27260156	HS294T	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.2333798011278344	[235]	[120,121,80,101]	3	hSpCas9	negative selection	6655934
52049812	52049835	10	+	27260156	HS294T	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.21125352518456753	[2362]	[986,921,1126,1231]	3	hSpCas9	negative selection	6675836
52049812	52049835	10	+	27260156	HS294T	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.21125352518456753	[2362]	[986,921,1126,1231]	3	hSpCas9	negative selection	6675840
51467755	51467778	10	+	27260156	HS294T	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.6933787405408149	[496]	[205,441,271,330]	8	hSpCas9	negative selection	6720190
51153258	51153281	10	-	27260156	HS294T	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.1718082326054341	[870]	[328,360,425,410]	2	hSpCas9	negative selection	6720191
51804609	51804632	10	-	27260156	HS294T	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	-0.26283387693617577	[229]	[62,67,74,94]	-4	hSpCas9	negative selection	6720192
51467817	51467840	10	-	27260156	HCC44	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.2080973647621469	[1230]	[1506,1549,2078,1371]	3	hSpCas9	negative selection	6777183
51804655	51804678	10	+	27260156	HCC44	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.34718782594219766	[307]	[461,364,535,434]	5	hSpCas9	negative selection	6777184
51153161	51153184	10	+	27260156	HCC44	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.3952952193712048	[235]	[316,476,260,310]	6	hSpCas9	negative selection	6777185
52049812	52049835	10	+	27260156	HCC44	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.21736808616950665	[2362]	[3427,3096,3430,2551]	3	hSpCas9	negative selection	6797087
52049812	52049835	10	+	27260156	HCC44	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.21736808616950665	[2362]	[3427,3096,3430,2551]	3	hSpCas9	negative selection	6797091
51467755	51467778	10	+	27260156	HCC44	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.25361205204162346	[496]	[611,478,858,775]	4	hSpCas9	negative selection	6841441
51153258	51153281	10	-	27260156	HCC44	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.3134976671688111	[870]	[1824,880,1249,1044]	5	hSpCas9	negative selection	6841442
51804609	51804632	10	-	27260156	HCC44	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.4540303327607649	[229]	[324,376,458,275]	7	hSpCas9	negative selection	6841443
51467817	51467840	10	-	27260156	G402	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.4275370567066561	[1230]	[1850,1842,2235,2103]	5	hSpCas9	negative selection	6898434
51804655	51804678	10	+	27260156	G402	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.9632793000929102	[307]	[563,373,513,1397]	9	hSpCas9	negative selection	6898435
51153161	51153184	10	+	27260156	G402	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	1.1882971433165084	[235]	[446,482,1544,132]	9	hSpCas9	negative selection	6898436
52049812	52049835	10	+	27260156	G402	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.468724298171348	[2362]	[4150,3310,4496,3970]	6	hSpCas9	negative selection	6918338
52049812	52049835	10	+	27260156	G402	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.468724298171348	[2362]	[4150,3310,4496,3970]	6	hSpCas9	negative selection	6918342
51467755	51467778	10	+	27260156	G402	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.2575486167828514	[496]	[745,407,417,484]	-3	hSpCas9	negative selection	6962692
51153258	51153281	10	-	27260156	G402	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.23860076258119178	[870]	[2339,847,1059,912]	3	hSpCas9	negative selection	6962693
51804609	51804632	10	-	27260156	G402	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.09197994778703478	[229]	[109,210,205,619]	1	hSpCas9	negative selection	6962694
51467817	51467840	10	-	27260156	L33	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.02221759297087811	[1230]	[1313,439,891,1192]	0	hSpCas9	negative selection	7019685
51804655	51804678	10	+	27260156	L33	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.09256096570892858	[307]	[271,133,229,349]	2	hSpCas9	negative selection	7019686
51153161	51153184	10	+	27260156	L33	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.06887365702666703	[235]	[200,95,166,199]	-1	hSpCas9	negative selection	7019687
52049812	52049835	10	+	27260156	L33	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.1071799277426706	[2362]	[2649,979,1559,2652]	2	hSpCas9	negative selection	7039589
52049812	52049835	10	+	27260156	L33	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.1071799277426706	[2362]	[2649,979,1559,2652]	2	hSpCas9	negative selection	7039593
51467755	51467778	10	+	27260156	L33	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.14323949772660816	[496]	[453,271,260,662]	3	hSpCas9	negative selection	7083943
51153258	51153281	10	-	27260156	L33	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	-0.047059568732568	[870]	[829,363,487,876]	-1	hSpCas9	negative selection	7083944
51804609	51804632	10	-	27260156	L33	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	-0.3280090722959279	[229]	[141,119,117,111]	-6	hSpCas9	negative selection	7083945
51467817	51467840	10	-	27260156	K562	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.523570493479834	[1230]	[1896,1334,1909,1191]	6	hSpCas9	negative selection	7140936
51804655	51804678	10	+	27260156	K562	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.061149676210109916	[307]	[411,520,177,75]	0	hSpCas9	negative selection	7140937
51153161	51153184	10	+	27260156	K562	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.853663027764326	[235]	[111,117,136,97]	-7	hSpCas9	negative selection	7140938
52049812	52049835	10	+	27260156	K562	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.23807388728548684	[2362]	[2290,2895,2317,2393]	3	hSpCas9	negative selection	7160840
52049812	52049835	10	+	27260156	K562	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.23807388728548684	[2362]	[2290,2895,2317,2393]	3	hSpCas9	negative selection	7160844
51467755	51467778	10	+	27260156	K562	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.12296505052355008	[496]	[328,490,413,384]	-1	hSpCas9	negative selection	7205194
51153258	51153281	10	-	27260156	K562	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.17568130906411727	[870]	[1153,953,546,861]	2	hSpCas9	negative selection	7205195
51804609	51804632	10	-	27260156	K562	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	-0.7156029943557651	[229]	[182,59,82,166]	-7	hSpCas9	negative selection	7205196
51467817	51467840	10	-	27260156	HT29	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.20640848050813498	[1230]	[1850,2014,1711,1391]	4	hSpCas9	negative selection	7262187
51804655	51804678	10	+	27260156	HT29	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.08845037434644776	[307]	[511,281,465,335]	1	hSpCas9	negative selection	7262188
51153161	51153184	10	+	27260156	HT29	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.00908123123739868	[235]	[316,379,212,243]	0	hSpCas9	negative selection	7262189
52049812	52049835	10	+	27260156	HT29	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.22134315535621818	[2362]	[3584,3793,3487,2647]	4	hSpCas9	negative selection	7282091
52049812	52049835	10	+	27260156	HT29	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.22134315535621818	[2362]	[3584,3793,3487,2647]	4	hSpCas9	negative selection	7282095
51467755	51467778	10	+	27260156	HT29	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.06544249928055257	[496]	[616,589,431,659]	-1	hSpCas9	negative selection	7326445
51153258	51153281	10	-	27260156	HT29	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.2798256383333809	[870]	[1226,1563,1274,1107]	5	hSpCas9	negative selection	7326446
51804609	51804632	10	-	27260156	HT29	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	-0.35054443046963035	[229]	[167,150,311,232]	-6	hSpCas9	negative selection	7326447
51467817	51467840	10	-	27260156	MHHES1	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.26652724582386056	[1230]	[1917,1626,1895,1304]	5	hSpCas9	negative selection	7383438
51804655	51804678	10	+	27260156	MHHES1	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.10958803433555742	[307]	[395,347,388,358]	2	hSpCas9	negative selection	7383439
51153161	51153184	10	+	27260156	MHHES1	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.2891793571127276	[235]	[384,567,161,229]	5	hSpCas9	negative selection	7383440
52049812	52049835	10	+	27260156	MHHES1	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.06123822210885699	[2362]	[3375,3402,2836,1795]	1	hSpCas9	negative selection	7403342
52049812	52049835	10	+	27260156	MHHES1	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.06123822210885699	[2362]	[3375,3402,2836,1795]	1	hSpCas9	negative selection	7403346
51467755	51467778	10	+	27260156	MHHES1	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.09050458227363838	[496]	[643,777,572,436]	1	hSpCas9	negative selection	7447696
51153258	51153281	10	-	27260156	MHHES1	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.25403828511520177	[870]	[1112,1605,1197,848]	4	hSpCas9	negative selection	7447697
51804609	51804632	10	-	27260156	MHHES1	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.005172882156218694	[229]	[210,379,301,168]	0	hSpCas9	negative selection	7447698
51467817	51467840	10	-	27260156	MEWO	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	-0.012493260682942209	[1230]	[1454,1074,955]	0	hSpCas9	negative selection	7504689
51804655	51804678	10	+	27260156	MEWO	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.05588318294533379	[307]	[347,283,275]	1	hSpCas9	negative selection	7504690
51153161	51153184	10	+	27260156	MEWO	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.16837027376789293	[235]	[265,163,172]	-4	hSpCas9	negative selection	7504691
52049812	52049835	10	+	27260156	MEWO	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.0918176094311205	[2362]	[3056,2006,2140]	2	hSpCas9	negative selection	7524593
52049812	52049835	10	+	27260156	MEWO	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.0918176094311205	[2362]	[3056,2006,2140]	2	hSpCas9	negative selection	7524597
51467755	51467778	10	+	27260156	MEWO	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.047458504150965045	[496]	[529,490,429]	1	hSpCas9	negative selection	7568947
51153258	51153281	10	-	27260156	MEWO	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.27034027478032774	[870]	[1182,983,819]	6	hSpCas9	negative selection	7568948
51804609	51804632	10	-	27260156	MEWO	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.004038794913570509	[229]	[253,154,245]	0	hSpCas9	negative selection	7568949
51467817	51467840	10	-	27260156	LNCAPCLONEFGC	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.44855046238382723	[1230]	[1440,1468,1716,1492]	7	hSpCas9	negative selection	7625940
51804655	51804678	10	+	27260156	LNCAPCLONEFGC	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.3294981396332377	[307]	[312,266,374,456]	5	hSpCas9	negative selection	7625941
51153161	51153184	10	+	27260156	LNCAPCLONEFGC	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.026000009395109824	[235]	[211,152,206,270]	0	hSpCas9	negative selection	7625942
52049812	52049835	10	+	27260156	LNCAPCLONEFGC	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.09805998955923023	[2362]	[2276,2135,2598,2206]	1	hSpCas9	negative selection	7645844
52049812	52049835	10	+	27260156	LNCAPCLONEFGC	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.09805998955923023	[2362]	[2276,2135,2598,2206]	1	hSpCas9	negative selection	7645848
51467755	51467778	10	+	27260156	LNCAPCLONEFGC	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.2092893886984643	[496]	[446,592,666,392]	3	hSpCas9	negative selection	7690198
51153258	51153281	10	-	27260156	LNCAPCLONEFGC	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.3513117379797718	[870]	[1007,801,1255,1009]	5	hSpCas9	negative selection	7690199
51804609	51804632	10	-	27260156	LNCAPCLONEFGC	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.1410044177726707	[229]	[257,186,390,108]	2	hSpCas9	negative selection	7690200
51467817	51467840	10	-	27260156	PANC0327	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.21400340729823197	[1230]	[1325,1188,1263,1308]	3	hSpCas9	negative selection	7747191
51804655	51804678	10	+	27260156	PANC0327	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.5867943479613468	[307]	[548,415,279,408]	8	hSpCas9	negative selection	7747192
51153161	51153184	10	+	27260156	PANC0327	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.06346636367105385	[235]	[108,191,391,177]	0	hSpCas9	negative selection	7747193
52049812	52049835	10	+	27260156	PANC0327	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.05264083048960844	[2362]	[2069,1901,2130,2630]	0	hSpCas9	negative selection	7767095
52049812	52049835	10	+	27260156	PANC0327	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.05264083048960844	[2362]	[2069,1901,2130,2630]	0	hSpCas9	negative selection	7767099
51467755	51467778	10	+	27260156	PANC0327	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.05197148644339887	[496]	[223,412,713,337]	-1	hSpCas9	negative selection	7811449
51153258	51153281	10	-	27260156	PANC0327	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.43880824030275034	[870]	[1123,1064,686,1321]	6	hSpCas9	negative selection	7811450
51804609	51804632	10	-	27260156	PANC0327	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.13437684939874506	[229]	[177,378,108,206]	2	hSpCas9	negative selection	7811451
51467817	51467840	10	-	27260156	NCIH2009	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.3719585987423395	[1230]	[2800,2012,1976]	5	hSpCas9	negative selection	7868442
51804655	51804678	10	+	27260156	NCIH2009	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.6441212736107822	[307]	[779,871,381]	8	hSpCas9	negative selection	7868443
51153161	51153184	10	+	27260156	NCIH2009	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.4073692004706704	[235]	[411,232,132]	-5	hSpCas9	negative selection	7868444
52049812	52049835	10	+	27260156	NCIH2009	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	-0.10892284945241659	[2362]	[3300,3080,2843]	-1	hSpCas9	negative selection	7888346
52049812	52049835	10	+	27260156	NCIH2009	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	-0.10892284945241659	[2362]	[3300,3080,2843]	-1	hSpCas9	negative selection	7888350
51467755	51467778	10	+	27260156	NCIH2009	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.10620052110467569	[496]	[707,704,820]	1	hSpCas9	negative selection	7932700
51153258	51153281	10	-	27260156	NCIH2009	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.0063616285675197615	[870]	[1425,1006,1275]	0	hSpCas9	negative selection	7932701
51804609	51804632	10	-	27260156	NCIH2009	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.49785381223884884	[229]	[599,368,421]	7	hSpCas9	negative selection	7932702
51467817	51467840	10	-	27260156	NCIH1373	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.5365470621090769	[1230]	[2613,1764,1614,561]	5	hSpCas9	negative selection	7989693
51804655	51804678	10	+	27260156	NCIH1373	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	1.4252021137285573	[307]	[857,753,1242,221]	9	hSpCas9	negative selection	7989694
51153161	51153184	10	+	27260156	NCIH1373	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.6822366023836295	[235]	[206,142,195,30]	-6	hSpCas9	negative selection	7989695
52049812	52049835	10	+	27260156	NCIH1373	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.1173618207526288	[2362]	[3428,2941,2417,727]	1	hSpCas9	negative selection	8009597
52049812	52049835	10	+	27260156	NCIH1373	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.1173618207526288	[2362]	[3428,2941,2417,727]	1	hSpCas9	negative selection	8009601
51467755	51467778	10	+	27260156	NCIH1373	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.1194330029079145	[496]	[1048,309,422,95]	-1	hSpCas9	negative selection	8053951
51153258	51153281	10	-	27260156	NCIH1373	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	-0.17849454982194723	[870]	[1148,839,567,248]	-2	hSpCas9	negative selection	8053952
51804609	51804632	10	-	27260156	NCIH1373	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.31365546354969975	[229]	[353,314,300,82]	3	hSpCas9	negative selection	8053953
51467817	51467840	10	-	27260156	PATU8902	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.27028298382255356	[1230]	[2027,1998,1491,2995]	2	hSpCas9	negative selection	8110944
51804655	51804678	10	+	27260156	PATU8902	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.8319040925181459	[307]	[1027,1103,392,596]	8	hSpCas9	negative selection	8110945
51153161	51153184	10	+	27260156	PATU8902	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.39379645167136323	[235]	[569,315,289,602]	4	hSpCas9	negative selection	8110946
52049812	52049835	10	+	27260156	PATU8902	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.08228103168290746	[2362]	[3529,4109,2360,4297]	0	hSpCas9	negative selection	8130848
52049812	52049835	10	+	27260156	PATU8902	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.08228103168290746	[2362]	[3529,4109,2360,4297]	0	hSpCas9	negative selection	8130852
51467755	51467778	10	+	27260156	PATU8902	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.657763400492399	[496]	[1188,825,967,1448]	7	hSpCas9	negative selection	8175202
51153258	51153281	10	-	27260156	PATU8902	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.27967718092053284	[870]	[1148,1838,1184,1827]	3	hSpCas9	negative selection	8175203
51804609	51804632	10	-	27260156	PATU8902	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.6429125681979695	[229]	[355,693,451,510]	6	hSpCas9	negative selection	8175204
51467817	51467840	10	-	27260156	PANC1	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.1143227839914962	[1230]	[1083,1277,1331,930]	1	hSpCas9	negative selection	8232195
51804655	51804678	10	+	27260156	PANC1	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.4720386592036477	[307]	[365,436,427,262]	7	hSpCas9	negative selection	8232196
51153161	51153184	10	+	27260156	PANC1	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.22472458933502426	[235]	[112,280,158,162]	-4	hSpCas9	negative selection	8232197
52049812	52049835	10	+	27260156	PANC1	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.14170413650729818	[2362]	[1980,2790,2283,2018]	2	hSpCas9	negative selection	8252099
52049812	52049835	10	+	27260156	PANC1	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.14170413650729818	[2362]	[1980,2790,2283,2018]	2	hSpCas9	negative selection	8252103
51467755	51467778	10	+	27260156	PANC1	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.026364513414987564	[496]	[444,548,397,372]	0	hSpCas9	negative selection	8296453
51153258	51153281	10	-	27260156	PANC1	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	-0.047326790537349894	[870]	[642,1036,839,472]	-1	hSpCas9	negative selection	8296454
51804609	51804632	10	-	27260156	PANC1	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.3625186019128236	[229]	[125,400,271,246]	6	hSpCas9	negative selection	8296455
51467817	51467840	10	-	27260156	PANC0813	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.15795290817477903	[1230]	[1677,1643,1400,1725]	2	hSpCas9	negative selection	8353446
51804655	51804678	10	+	27260156	PANC0813	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.8456088037157565	[307]	[712,752,754,398]	9	hSpCas9	negative selection	8353447
51153161	51153184	10	+	27260156	PANC0813	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.23702065926305826	[235]	[389,258,417,249]	4	hSpCas9	negative selection	8353448
52049812	52049835	10	+	27260156	PANC0813	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.1532495482171652	[2362]	[3023,3324,3310,2698]	2	hSpCas9	negative selection	8373350
52049812	52049835	10	+	27260156	PANC0813	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.1532495482171652	[2362]	[3023,3324,3310,2698]	2	hSpCas9	negative selection	8373354
51467755	51467778	10	+	27260156	PANC0813	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.04196249779678719	[496]	[590,772,585,459]	0	hSpCas9	negative selection	8417704
51153258	51153281	10	-	27260156	PANC0813	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.21225877582078645	[870]	[1312,1184,1300,964]	3	hSpCas9	negative selection	8417705
51804609	51804632	10	-	27260156	PANC0813	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	-0.016741298982000385	[229]	[329,240,244,257]	0	hSpCas9	negative selection	8417706
51467817	51467840	10	-	27260156	RDES	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.3400015664985574	[1230]	[1446,1569,1963,2315]	5	hSpCas9	negative selection	8474697
51804655	51804678	10	+	27260156	RDES	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.4401279496574829	[307]	[381,425,469,687]	7	hSpCas9	negative selection	8474698
51153161	51153184	10	+	27260156	RDES	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.13075612866954134	[235]	[210,314,280,405]	2	hSpCas9	negative selection	8474699
52049812	52049835	10	+	27260156	RDES	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.31413353699226354	[2362]	[2732,3479,3360,4070]	5	hSpCas9	negative selection	8494601
52049812	52049835	10	+	27260156	RDES	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.31413353699226354	[2362]	[2732,3479,3360,4070]	5	hSpCas9	negative selection	8494605
51467755	51467778	10	+	27260156	RDES	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.28894993461117247	[496]	[574,559,788,926]	4	hSpCas9	negative selection	8538955
51153258	51153281	10	-	27260156	RDES	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.19128024973557511	[870]	[830,1122,1073,1659]	3	hSpCas9	negative selection	8538956
51804609	51804632	10	-	27260156	RDES	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.44313740584722305	[229]	[282,401,272,499]	7	hSpCas9	negative selection	8538957
51467817	51467840	10	-	27260156	PC3	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	-0.22364509495664997	[1230]	[751,993,1820,950]	-5	hSpCas9	negative selection	8595948
51804655	51804678	10	+	27260156	PC3	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.25105818774589095	[307]	[234,248,420,616]	5	hSpCas9	negative selection	8595949
51153161	51153184	10	+	27260156	PC3	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.22397176820387243	[235]	[143,240,152,250]	-5	hSpCas9	negative selection	8595950
52049812	52049835	10	+	27260156	PC3	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.05045639655298073	[2362]	[1635,2515,3704,2487]	1	hSpCas9	negative selection	8615852
52049812	52049835	10	+	27260156	PC3	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.05045639655298073	[2362]	[1635,2515,3704,2487]	1	hSpCas9	negative selection	8615856
51467755	51467778	10	+	27260156	PC3	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.22696941599899212	[496]	[226,228,730,700]	-5	hSpCas9	negative selection	8660206
51153258	51153281	10	-	27260156	PC3	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.09950994268587543	[870]	[639,1218,1151,798]	2	hSpCas9	negative selection	8660207
51804609	51804632	10	-	27260156	PC3	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	-0.015646902615160663	[229]	[176,77,433,306]	0	hSpCas9	negative selection	8660208
51467817	51467840	10	-	27260156	PATU8988T	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	-0.06123927663063533	[1230]	[832,1234,858,1689]	-1	hSpCas9	negative selection	8717199
51804655	51804678	10	+	27260156	PATU8988T	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.3892424829277339	[307]	[222,685,359,311]	6	hSpCas9	negative selection	8717200
51153161	51153184	10	+	27260156	PATU8988T	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.25585304653819374	[235]	[150,250,412,269]	4	hSpCas9	negative selection	8717201
52049812	52049835	10	+	27260156	PATU8988T	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.01793244967132246	[2362]	[2385,2407,1873,2618]	0	hSpCas9	negative selection	8737103
52049812	52049835	10	+	27260156	PATU8988T	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.01793244967132246	[2362]	[2385,2407,1873,2618]	0	hSpCas9	negative selection	8737107
51467755	51467778	10	+	27260156	PATU8988T	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.00845792765298986	[496]	[608,477,552,273]	0	hSpCas9	negative selection	8781457
51153258	51153281	10	-	27260156	PATU8988T	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.3305035614296633	[870]	[903,1219,1252,851]	5	hSpCas9	negative selection	8781458
51804609	51804632	10	-	27260156	PATU8988T	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.09244611144408821	[229]	[78,378,154,358]	1	hSpCas9	negative selection	8781459
51467817	51467840	10	-	27260156	T47D	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.12163825675211304	[1230]	[1637,1405,1523,1690]	2	hSpCas9	negative selection	8838450
51804655	51804678	10	+	27260156	T47D	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.24862402528234684	[307]	[430,420,457,393]	5	hSpCas9	negative selection	8838451
51153161	51153184	10	+	27260156	T47D	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.09999640854532621	[235]	[258,340,226,189]	-2	hSpCas9	negative selection	8838452
52049812	52049835	10	+	27260156	T47D	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.06303411783453505	[2362]	[3010,2625,2876,3014]	1	hSpCas9	negative selection	8858354
52049812	52049835	10	+	27260156	T47D	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.06303411783453505	[2362]	[3010,2625,2876,3014]	1	hSpCas9	negative selection	8858358
51467755	51467778	10	+	27260156	T47D	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.09696692757080029	[496]	[537,547,612,461]	-2	hSpCas9	negative selection	8902708
51153258	51153281	10	-	27260156	T47D	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.030134932060957298	[870]	[989,964,1120,1073]	0	hSpCas9	negative selection	8902709
51804609	51804632	10	-	27260156	T47D	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.008063795736540147	[229]	[291,254,265,265]	0	hSpCas9	negative selection	8902710
51467817	51467840	10	-	27260156	SU8686	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.33719147096675584	[1230]	[1267,1356,1818,1819]	6	hSpCas9	negative selection	8959701
51804655	51804678	10	+	27260156	SU8686	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.606089067634223	[307]	[382,408,536,560]	8	hSpCas9	negative selection	8959702
51153161	51153184	10	+	27260156	SU8686	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.08154120030778644	[235]	[218,217,197,252]	-1	hSpCas9	negative selection	8959703
52049812	52049835	10	+	27260156	SU8686	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.14531512711683714	[2362]	[2206,2544,2658,3061]	2	hSpCas9	negative selection	8979605
52049812	52049835	10	+	27260156	SU8686	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.14531512711683714	[2362]	[2206,2544,2658,3061]	2	hSpCas9	negative selection	8979609
51467755	51467778	10	+	27260156	SU8686	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.22639292160719782	[496]	[515,401,692,751]	4	hSpCas9	negative selection	9023959
51153258	51153281	10	-	27260156	SU8686	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.2662074016062287	[870]	[821,1074,1085,1212]	4	hSpCas9	negative selection	9023960
51804609	51804632	10	-	27260156	SU8686	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.31936164529921174	[229]	[166,192,411,413]	5	hSpCas9	negative selection	9023961
51467817	51467840	10	-	27260156	SKES1	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.04727115367102286	[1230]	[1340,1465,1137,1164]	1	hSpCas9	negative selection	9080952
51804655	51804678	10	+	27260156	SKES1	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.4950194401156242	[307]	[509,494,410,340]	8	hSpCas9	negative selection	9080953
51153161	51153184	10	+	27260156	SKES1	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.3533631222882443	[235]	[212,257,70,204]	-7	hSpCas9	negative selection	9080954
52049812	52049835	10	+	27260156	SKES1	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.07532477250039804	[2362]	[2933,2247,2575,2214]	1	hSpCas9	negative selection	9100856
52049812	52049835	10	+	27260156	SKES1	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.07532477250039804	[2362]	[2933,2247,2575,2214]	1	hSpCas9	negative selection	9100860
51467755	51467778	10	+	27260156	SKES1	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.06537720057629078	[496]	[443,516,482,449]	-1	hSpCas9	negative selection	9145210
51153258	51153281	10	-	27260156	SKES1	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.22108137840495046	[870]	[1122,856,1206,864]	5	hSpCas9	negative selection	9145211
51804609	51804632	10	-	27260156	SKES1	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	-0.11650865994537063	[229]	[175,288,253,137]	-3	hSpCas9	negative selection	9145212
51467817	51467840	10	-	27260156	TOV112D	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.1379509786820572	[1230]	[1160,1676,1088,1553]	2	hSpCas9	negative selection	9202203
51804655	51804678	10	+	27260156	TOV112D	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	0.563360866269012	[307]	[258,530,450,579]	8	hSpCas9	negative selection	9202204
51153161	51153184	10	+	27260156	TOV112D	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.569826376925016	[235]	[182,166,181,109]	-8	hSpCas9	negative selection	9202205
52049812	52049835	10	+	27260156	TOV112D	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.07903367982486609	[2362]	[2893,2365,2496,2245]	1	hSpCas9	negative selection	9222107
52049812	52049835	10	+	27260156	TOV112D	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.07903367982486609	[2362]	[2893,2365,2496,2245]	1	hSpCas9	negative selection	9222111
51467755	51467778	10	+	27260156	TOV112D	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.27078165918089364	[496]	[394,630,751,612]	5	hSpCas9	negative selection	9266461
51153258	51153281	10	-	27260156	TOV112D	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.2449787737085699	[870]	[953,1634,661,1023]	5	hSpCas9	negative selection	9266462
51804609	51804632	10	-	27260156	TOV112D	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	-0.5302504647543671	[229]	[201,163,136,139]	-8	hSpCas9	negative selection	9266463
51467817	51467840	10	-	27260156	TC71	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	-0.002915854803300588	[1230]	[1226,1271,1191,1599]	0	hSpCas9	negative selection	9323454
51804655	51804678	10	+	27260156	TC71	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	-0.0016061494877294136	[307]	[275,338,352,352]	0	hSpCas9	negative selection	9323455
51153161	51153184	10	+	27260156	TC71	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	-0.11723467634212792	[235]	[148,274,279,228]	-3	hSpCas9	negative selection	9323456
52049812	52049835	10	+	27260156	TC71	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.0016623644641149404	[2362]	[2485,2774,2348,2540]	0	hSpCas9	negative selection	9343358
52049812	52049835	10	+	27260156	TC71	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.0016623644641149404	[2362]	[2485,2774,2348,2540]	0	hSpCas9	negative selection	9343362
51467755	51467778	10	+	27260156	TC71	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	-0.14742143770906613	[496]	[453,550,468,448]	-4	hSpCas9	negative selection	9387712
51153258	51153281	10	-	27260156	TC71	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.0637090336174938	[870]	[1034,876,1028,957]	1	hSpCas9	negative selection	9387713
51804609	51804632	10	-	27260156	TC71	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	-0.19510413477258615	[229]	[210,227,244,173]	-5	hSpCas9	negative selection	9387714
51467817	51467840	10	-	27260156	TC32	viability	TACTCTTGACGGTCGCTGTCCGG	PRKG1	ENSG00000185532	0.3513910924991841	[1230]	[1413,1116,1712,1771]	6	hSpCas9	negative selection	9444705
51804655	51804678	10	+	27260156	TC32	viability	CATCAAGCATACCGAGTATATGG	PRKG1	ENSG00000185532	-0.07832933177745671	[307]	[230,127,446,372]	-1	hSpCas9	negative selection	9444706
51153161	51153184	10	+	27260156	TC32	viability	TAGGTCCAAGGATCTTATAAAGG	PRKG1	ENSG00000185532	0.2594900539680216	[235]	[202,232,257,376]	4	hSpCas9	negative selection	9444707
52049812	52049835	10	+	27260156	TC32	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.2077572320094383	[2362]	[2458,2246,3103,2509]	4	hSpCas9	negative selection	9464609
52049812	52049835	10	+	27260156	TC32	viability	TTGAGTCCCTACTATGTTCCAAG	PRKG1	ENSG00000185532	0.2077572320094383	[2362]	[2458,2246,3103,2509]	4	hSpCas9	negative selection	9464613
51467755	51467778	10	+	27260156	TC32	viability	AAGTTGTGTACCATGGGTCCAGG	PRKG1	ENSG00000185532	0.06212986514039022	[496]	[380,459,539,576]	1	hSpCas9	negative selection	9508963
51153258	51153281	10	-	27260156	TC32	viability	CTGTCCTTGCCATACTCCACCGG	PRKG1	ENSG00000185532	0.2726601356443378	[870]	[791,732,1230,1324]	5	hSpCas9	negative selection	9508964
51804609	51804632	10	-	27260156	TC32	viability	TTGAAAACATTGTCGATCAATGG	PRKG1	ENSG00000185532	0.13888328257584515	[229]	[198,133,358,316]	2	hSpCas9	negative selection	9508965
50991520	50991543	10	-	27869803	HPAFII	viability after 27 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-0.36784405291399913	[379]	[204,112,NaN]	-3	hSpCas9	negative selection	9538104
51074866	51074889	10	-	27869803	HPAFII	viability after 27 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	0.8863577916491905	[70]	[2,123,NaN]	7	hSpCas9	negative selection	9538105
51153284	51153307	10	+	27869803	HPAFII	viability after 27 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-0.10893526178940488	[330]	[252,84,NaN]	-1	hSpCas9	negative selection	9538106
51467748	51467771	10	+	27869803	HPAFII	viability after 27 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	1.182682575369505	[571]	[794,588,NaN]	8	hSpCas9	negative selection	9538107
52054509	52054532	10	+	27869803	HPAFII	viability after 27 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.9145329414515683	[413]	[256,537,NaN]	7	hSpCas9	negative selection	9538114
50991520	50991543	10	-	27869803	HPAFII	viability after 15 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-0.03125510912871288	[379]	[694,215,NaN]	0	hSpCas9	negative selection	9620553
51074866	51074889	10	-	27869803	HPAFII	viability after 15 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	0.8170775161360008	[70]	[184,102,NaN]	8	hSpCas9	negative selection	9620554
51153284	51153307	10	+	27869803	HPAFII	viability after 15 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-0.061497278020201385	[330]	[589,185,NaN]	0	hSpCas9	negative selection	9620555
51467748	51467771	10	+	27869803	HPAFII	viability after 15 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.8599741733085511	[571]	[1465,897,NaN]	8	hSpCas9	negative selection	9620556
52054509	52054532	10	+	27869803	HPAFII	viability after 15 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.22975608657908697	[413]	[530,515,NaN]	2	hSpCas9	negative selection	9620563
50991520	50991543	10	-	27869803	ASPC1	viability after 36 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	0.4900728500742776	[877]	[322,673,307]	5	hSpCas9	negative selection	9703002
51074866	51074889	10	-	27869803	ASPC1	viability after 36 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	0.7694064485875354	[156]	[28,131,106]	7	hSpCas9	negative selection	9703003
51153284	51153307	10	+	27869803	ASPC1	viability after 36 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	0.26564833190652737	[766]	[309,531,159]	2	hSpCas9	negative selection	9703004
51467748	51467771	10	+	27869803	ASPC1	viability after 36 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	-0.03188585810186173	[1762]	[776,762,344]	0	hSpCas9	negative selection	9703005
52054509	52054532	10	+	27869803	ASPC1	viability after 36 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	-0.34979785607361735	[826]	[252,128,282]	-4	hSpCas9	negative selection	9703012
50991520	50991543	10	-	27869803	PATU8988S	viability after 35 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	0.04391495688559055	[771]	[334,305,NaN]	0	hSpCas9	negative selection	9785451
51074866	51074889	10	-	27869803	PATU8988S	viability after 35 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	0.8832301186347762	[98]	[92,53,NaN]	8	hSpCas9	negative selection	9785452
51153284	51153307	10	+	27869803	PATU8988S	viability after 35 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	0.431254918065201	[668]	[281,444,NaN]	5	hSpCas9	negative selection	9785453
51467748	51467771	10	+	27869803	PATU8988S	viability after 35 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.1711801305143661	[1535]	[721,670,NaN]	2	hSpCas9	negative selection	9785454
52054509	52054532	10	+	27869803	PATU8988S	viability after 35 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.05132678698550164	[810]	[320,355,NaN]	0	hSpCas9	negative selection	9785461
50991520	50991543	10	-	27869803	PATU8988S	viability after 31 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	0.3148092269399335	[771]	[253,546,NaN]	4	hSpCas9	negative selection	9867900
51074866	51074889	10	-	27869803	PATU8988S	viability after 31 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	0.1273260443308275	[98]	[32,55,NaN]	1	hSpCas9	negative selection	9867901
51153284	51153307	10	+	27869803	PATU8988S	viability after 31 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	0.25302473538868064	[668]	[210,453,NaN]	3	hSpCas9	negative selection	9867902
51467748	51467771	10	+	27869803	PATU8988S	viability after 31 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	0.033445390525026264	[1535]	[599,660,NaN]	0	hSpCas9	negative selection	9867903
52054509	52054532	10	+	27869803	PATU8988S	viability after 31 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.26147226022313386	[810]	[373,404,NaN]	3	hSpCas9	negative selection	9867910
50991520	50991543	10	-	27869803	HPAFII	viability after 35 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-0.5170468253263092	[379]	[172,90,NaN]	-3	hSpCas9	negative selection	9950349
51074866	51074889	10	-	27869803	HPAFII	viability after 35 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	0.4041765002275368	[70]	[0,99,NaN]	2	hSpCas9	negative selection	9950350
51153284	51153307	10	+	27869803	HPAFII	viability after 35 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	-0.15951407809683338	[330]	[205,86,NaN]	-1	hSpCas9	negative selection	9950351
51467748	51467771	10	+	27869803	HPAFII	viability after 35 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	1.3592974643349216	[571]	[598,904,NaN]	8	hSpCas9	negative selection	9950352
52054509	52054532	10	+	27869803	HPAFII	viability after 35 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	1.2863389286401192	[413]	[315,730,NaN]	8	hSpCas9	negative selection	9950359
50991520	50991543	10	-	27869803	HPAFII	viability after 31 days	CCGATGTGGGTCGAGGGCACTGG	PRKG1	ENSG00000185532	-0.665022046099066	[379]	[167,97,NaN]	-4	hSpCas9	negative selection	10032798
51074866	51074889	10	-	27869803	HPAFII	viability after 31 days	GGTAGAAGGGCAGGGTCACATGG	PRKG1	ENSG00000185532	0.7298906138617995	[70]	[0,136,NaN]	5	hSpCas9	negative selection	10032799
51153284	51153307	10	+	27869803	HPAFII	viability after 31 days	CATCATCAAAGAAGGAGACGTGG	PRKG1	ENSG00000185532	0.012935855137025887	[330]	[252,115,NaN]	0	hSpCas9	negative selection	10032800
51467748	51467771	10	+	27869803	HPAFII	viability after 31 days	AGGTGTGAAGTTGTGTACCATGG	PRKG1	ENSG00000185532	1.4375776345597464	[571]	[869,868,NaN]	9	hSpCas9	negative selection	10032801
52054509	52054532	10	+	27869803	HPAFII	viability after 31 days	TTATCAGGCAAGGTGCAAGAGGG	PRKG1	ENSG00000185532	0.9402526222564881	[413]	[296,607,NaN]	7	hSpCas9	negative selection	10032808
52062610	52062633	10	+	28162770	P31FUJ	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	-0.5565906413272689	[193]	[154]	-5	hSpCas9	negative selection	10217190
51153242	51153265	10	+	28162770	P31FUJ	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.8529276696115053	[48]	[103]	8	hSpCas9	negative selection	10217191
51153254	51153277	10	+	28162770	P31FUJ	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.05207890371766388	[567]	[691]	0	hSpCas9	negative selection	10217192
51153285	51153308	10	+	28162770	P31FUJ	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	-0.13612618500270468	[100]	[107]	-1	hSpCas9	negative selection	10217193
51907540	51907563	10	-	28162770	P31FUJ	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	0.5551473184706325	[416]	[719]	6	hSpCas9	negative selection	10217194
52062610	52062633	10	+	28162770	TF1	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10386556
51153242	51153265	10	+	28162770	TF1	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10386557
51153254	51153277	10	+	28162770	TF1	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	NaN	[NaN]	[545]	1	hSpCas9	negative selection	10386558
51153285	51153308	10	+	28162770	TF1	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	NaN	[NaN]	[90]	1	hSpCas9	negative selection	10386559
51907540	51907563	10	-	28162770	TF1	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	NaN	[NaN]	[337]	1	hSpCas9	negative selection	10386560
52062610	52062633	10	+	28162770	SKM1	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	-0.7080455087249198	[72]	[78]	-5	hSpCas9	negative selection	10555922
51153242	51153265	10	+	28162770	SKM1	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	-0.19397047540896328	[21]	[33]	-2	hSpCas9	negative selection	10555923
51153254	51153277	10	+	28162770	SKM1	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.6296942718356866	[135]	[371]	6	hSpCas9	negative selection	10555924
51153285	51153308	10	+	28162770	SKM1	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	0.2681961109495725	[30]	[65]	2	hSpCas9	negative selection	10555925
51907540	51907563	10	-	28162770	SKM1	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	0.08607581253695518	[80]	[151]	0	hSpCas9	negative selection	10555926
52062610	52062633	10	+	28162770	SKM1	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	-0.7080455087249198	[72]	[78]	-5	hSpCas9	negative selection	10725288
51153242	51153265	10	+	28162770	SKM1	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	-0.19397047540896328	[21]	[33]	-2	hSpCas9	negative selection	10725289
51153254	51153277	10	+	28162770	SKM1	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.6296942718356866	[135]	[371]	6	hSpCas9	negative selection	10725290
51153285	51153308	10	+	28162770	SKM1	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	0.2681961109495725	[30]	[65]	2	hSpCas9	negative selection	10725291
51907540	51907563	10	-	28162770	SKM1	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	0.08607581253695518	[80]	[151]	0	hSpCas9	negative selection	10725292
52062610	52062633	10	+	28162770	PL21	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	-0.25929200414797715	[230]	[83]	-2	hSpCas9	negative selection	10894654
51153242	51153265	10	+	28162770	PL21	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	-0.25442624897616084	[73]	[26]	-2	hSpCas9	negative selection	10894655
51153254	51153277	10	+	28162770	PL21	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	1.0835957093750315	[450]	[415]	8	hSpCas9	negative selection	10894656
51153285	51153308	10	+	28162770	PL21	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	-1.7154681982203073	[82]	[10]	-8	hSpCas9	negative selection	10894657
51907540	51907563	10	-	28162770	PL21	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	-0.04658213620886842	[298]	[125]	0	hSpCas9	negative selection	10894658
52062610	52062633	10	+	28162770	P31FUJ	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	-0.5565906413272689	[193]	[154]	-5	hSpCas9	negative selection	11064020
51153242	51153265	10	+	28162770	P31FUJ	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.8529276696115053	[48]	[103]	8	hSpCas9	negative selection	11064021
51153254	51153277	10	+	28162770	P31FUJ	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.05207890371766388	[567]	[691]	0	hSpCas9	negative selection	11064022
51153285	51153308	10	+	28162770	P31FUJ	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	-0.13612618500270468	[100]	[107]	-1	hSpCas9	negative selection	11064023
51907540	51907563	10	-	28162770	P31FUJ	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	0.5551473184706325	[416]	[719]	6	hSpCas9	negative selection	11064024
52062610	52062633	10	+	28162770	OCIAML5	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	1.184002683843525	[78]	[323]	8	hSpCas9	negative selection	11233386
51153242	51153265	10	+	28162770	OCIAML5	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.41096783496979694	[39]	[95]	3	hSpCas9	negative selection	11233387
51153254	51153277	10	+	28162770	OCIAML5	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.30420936906646423	[235]	[525]	2	hSpCas9	negative selection	11233388
51153285	51153308	10	+	28162770	OCIAML5	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	-0.35296480679667863	[74]	[105]	-3	hSpCas9	negative selection	11233389
51907540	51907563	10	-	28162770	OCIAML5	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	0.08322773974818776	[284]	[544]	0	hSpCas9	negative selection	11233390
52062610	52062633	10	+	28162770	EOL1	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	0.5434576042150285	[335]	[257]	5	hSpCas9	negative selection	11402752
51153242	51153265	10	+	28162770	EOL1	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	1.4752403702069445	[70]	[103]	9	hSpCas9	negative selection	11402753
51153254	51153277	10	+	28162770	EOL1	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	-0.07545222842946542	[945]	[472]	0	hSpCas9	negative selection	11402754
51153285	51153308	10	+	28162770	EOL1	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	0.06086924278331507	[110]	[60]	0	hSpCas9	negative selection	11402755
51907540	51907563	10	-	28162770	EOL1	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	-0.7558342942293041	[499]	[155]	-5	hSpCas9	negative selection	11402756
52062610	52062633	10	+	28162770	MOLM13	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	0.3874395491245627	[294]	[278]	3	hSpCas9	negative selection	11572118
51153242	51153265	10	+	28162770	MOLM13	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.6973712276673463	[57]	[67]	5	hSpCas9	negative selection	11572119
51153254	51153277	10	+	28162770	MOLM13	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.5016776950008623	[632]	[647]	4	hSpCas9	negative selection	11572120
51153285	51153308	10	+	28162770	MOLM13	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	-1.388746443284244	[133]	[36]	-6	hSpCas9	negative selection	11572121
51907540	51907563	10	-	28162770	MOLM13	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	0.5500276681150572	[494]	[523]	4	hSpCas9	negative selection	11572122
52062610	52062633	10	+	28162770	HEL	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	0.6081401704763902	[210]	[205]	5	hSpCas9	negative selection	11741484
51153242	51153265	10	+	28162770	HEL	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	-0.6285631898170372	[69]	[28]	-4	hSpCas9	negative selection	11741485
51153254	51153277	10	+	28162770	HEL	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.32837784565826844	[617]	[496]	2	hSpCas9	negative selection	11741486
51153285	51153308	10	+	28162770	HEL	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	-0.335566096900324	[131]	[66]	-2	hSpCas9	negative selection	11741487
51907540	51907563	10	-	28162770	HEL	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	0.4345663612010815	[386]	[334]	3	hSpCas9	negative selection	11741488
52062610	52062633	10	+	28162770	MV411	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	-0.05212273107613244	[159]	[129]	0	hSpCas9	negative selection	11910850
51153242	51153265	10	+	28162770	MV411	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	1.0444505286189205	[79]	[138]	8	hSpCas9	negative selection	11910851
51153254	51153277	10	+	28162770	MV411	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.524225111683899	[434]	[526]	5	hSpCas9	negative selection	11910852
51153285	51153308	10	+	28162770	MV411	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	0.802405311206094	[80]	[118]	7	hSpCas9	negative selection	11910853
51907540	51907563	10	-	28162770	MV411	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	0.20717368056904828	[326]	[317]	1	hSpCas9	negative selection	11910854
52062610	52062633	10	+	28162770	MONOMAC1	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	0.5619550534366515	[116]	[197]	5	hSpCas9	negative selection	12080216
51153242	51153265	10	+	28162770	MONOMAC1	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	-0.9340024412257597	[44]	[26]	-6	hSpCas9	negative selection	12080217
51153254	51153277	10	+	28162770	MONOMAC1	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.22334199501396879	[336]	[450]	2	hSpCas9	negative selection	12080218
51153285	51153308	10	+	28162770	MONOMAC1	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	-0.0757305508374202	[56]	[61]	0	hSpCas9	negative selection	12080219
51907540	51907563	10	-	28162770	MONOMAC1	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	-0.5271854487518846	[219]	[174]	-4	hSpCas9	negative selection	12080220
52062610	52062633	10	+	28162770	OCIAML2	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	-0.15611920191728193	[38]	[193]	-1	hSpCas9	negative selection	12249582
51153242	51153265	10	+	28162770	OCIAML2	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	-0.0971714297147166	[10]	[56]	-1	hSpCas9	negative selection	12249583
51153254	51153277	10	+	28162770	OCIAML2	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.6337068345725743	[79]	[687]	6	hSpCas9	negative selection	12249584
51153285	51153308	10	+	28162770	OCIAML2	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	-0.200540661874417	[16]	[81]	-2	hSpCas9	negative selection	12249585
51907540	51907563	10	-	28162770	OCIAML2	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	0.1638884999532274	[61]	[384]	1	hSpCas9	negative selection	12249586
52062610	52062633	10	+	28162770	OCIAML3	viability	TTGGAGAGAAAGCCTTGCAGGGG	PRKG1	ENSG00000185532	1.093316578026671	[33]	[218]	8	hSpCas9	negative selection	12418948
51153242	51153265	10	+	28162770	OCIAML3	viability	TGTGGATTGTATGTACCCGGTGG	PRKG1	ENSG00000185532	0.7716418319925171	[12]	[66]	7	hSpCas9	negative selection	12418949
51153254	51153277	10	+	28162770	OCIAML3	viability	GTACCCGGTGGAGTATGGCAAGG	PRKG1	ENSG00000185532	0.5055280332267513	[132]	[569]	5	hSpCas9	negative selection	12418950
51153285	51153308	10	+	28162770	OCIAML3	viability	ATCATCAAAGAAGGAGACGTGGG	PRKG1	ENSG00000185532	-0.8570420461579571	[23]	[39]	-6	hSpCas9	negative selection	12418951
51907540	51907563	10	-	28162770	OCIAML3	viability	GGACATCAGCAAGCTTGCTGAGG	PRKG1	ENSG00000185532	-0.061133650751461155	[93]	[271]	0	hSpCas9	negative selection	12418952