Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5625
• Symbol: PRODH
• Description: proline dehydrogenase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PRODH

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
18931009	18931032	22	-	26472758	Jiyoye	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-2.980554771777235	[156]	[14]	-9	hSpCas9	negative selection	127762
18931046	18931069	22	+	26472758	Jiyoye	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	1.416393911535252	[77]	[156]	8	hSpCas9	negative selection	127763
18913474	18913497	22	+	26472758	Jiyoye	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.08317295838065253	[173]	[138]	0	hSpCas9	negative selection	127764
18931068	18931091	22	+	26472758	Jiyoye	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-0.9876842358353399	[70]	[26]	-6	hSpCas9	negative selection	127765
18930991	18931014	22	-	26472758	Jiyoye	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	1.5998204594482692	[34]	[79]	8	hSpCas9	negative selection	127766
18925703	18925726	22	-	26472758	Jiyoye	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	0.4580762798059115	[361]	[374]	3	hSpCas9	negative selection	127767
18925687	18925710	22	-	26472758	Jiyoye	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-1.6879818515344667	[93]	[21]	-8	hSpCas9	negative selection	127768
18919753	18919776	22	-	26472758	Jiyoye	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	0.61461746137635	[96]	[111]	4	hSpCas9	negative selection	127769
18919507	18919530	22	+	26472758	Jiyoye	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	0.6678271360286732	[100]	[120]	5	hSpCas9	negative selection	127770
18918312	18918335	22	+	26472758	Jiyoye	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	-1.490945004474913	[204]	[54]	-7	hSpCas9	negative selection	127771
18931009	18931032	22	-	26472758	KBM7	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-2.226448782591002	[596,373]	[21,70]	-8	hSpCas9	negative selection	318880
18931046	18931069	22	+	26472758	KBM7	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	0.7746679588396723	[390,366]	[307,302]	8	hSpCas9	negative selection	318881
18913474	18913497	22	+	26472758	KBM7	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.7777320167242348	[364,237]	[276,204]	8	hSpCas9	negative selection	318882
18931068	18931091	22	+	26472758	KBM7	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	0.23676794727916706	[150,190]	[89,101]	2	hSpCas9	negative selection	318883
18930991	18931014	22	-	26472758	KBM7	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-0.3811010701878593	[334,284]	[72,145]	-4	hSpCas9	negative selection	318884
18925703	18925726	22	-	26472758	KBM7	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.7803329261536334	[2021,1454]	[473,466]	-6	hSpCas9	negative selection	318885
18925687	18925710	22	-	26472758	KBM7	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-1.5579291489941434	[505,351]	[65,68]	-8	hSpCas9	negative selection	318886
18919753	18919776	22	-	26472758	KBM7	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	0.06857502799684079	[382,439]	[151,252]	0	hSpCas9	negative selection	318887
18919507	18919530	22	+	26472758	KBM7	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	0.1276606144207176	[640,483]	[262,306]	1	hSpCas9	negative selection	318888
18918312	18918335	22	+	26472758	KBM7	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	0.1782362325312088	[591,796]	[539,230]	1	hSpCas9	negative selection	318889
18931009	18931032	22	-	26472758	Raji	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-2.9861283505495453	[238]	[6]	-9	hSpCas9	negative selection	509998
18931046	18931069	22	+	26472758	Raji	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	-0.09829149101791468	[142]	[30]	-1	hSpCas9	negative selection	509999
18913474	18913497	22	+	26472758	Raji	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.5360314661710965	[210]	[70]	5	hSpCas9	negative selection	510000
18931068	18931091	22	+	26472758	Raji	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-0.8926164646264005	[71]	[8]	-6	hSpCas9	negative selection	510001
18930991	18931014	22	-	26472758	Raji	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-1.604690883250896	[248]	[18]	-8	hSpCas9	negative selection	510002
18925703	18925726	22	-	26472758	Raji	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	0.17036096842392645	[761]	[198]	1	hSpCas9	negative selection	510003
18925687	18925710	22	-	26472758	Raji	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-3.477578965347557	[239]	[4]	-9	hSpCas9	negative selection	510004
18919753	18919776	22	-	26472758	Raji	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	0.5224210346524432	[203]	[67]	5	hSpCas9	negative selection	510005
18919507	18919530	22	+	26472758	Raji	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	-0.3265129911565601	[307]	[56]	-3	hSpCas9	negative selection	510006
18918312	18918335	22	+	26472758	Raji	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	0.2773085368159119	[223]	[62]	2	hSpCas9	negative selection	510007
18931009	18931032	22	-	26472758	K562	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-5.939748196351644	[508]	[6]	-9	hSpCas9	negative selection	701116
18931046	18931069	22	+	26472758	K562	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	-0.90495889637178	[365]	[164]	-5	hSpCas9	negative selection	701117
18913474	18913497	22	+	26472758	K562	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.6645272164927127	[283]	[379]	5	hSpCas9	negative selection	701118
18931068	18931091	22	+	26472758	K562	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-0.9814626797498809	[137]	[58]	-5	hSpCas9	negative selection	701119
18930991	18931014	22	-	26472758	K562	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-0.42132642777075535	[302]	[190]	-3	hSpCas9	negative selection	701120
18925703	18925726	22	-	26472758	K562	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-1.3723224817273703	[1376]	[448]	-6	hSpCas9	negative selection	701121
18925687	18925710	22	-	26472758	K562	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-4.035689191526288	[271]	[13]	-9	hSpCas9	negative selection	701122
18919753	18919776	22	-	26472758	K562	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	0.036101491541721834	[356]	[308]	0	hSpCas9	negative selection	701123
18919507	18919530	22	+	26472758	K562	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	1.3364792806552146	[386]	[824]	9	hSpCas9	negative selection	701124
18918312	18918335	22	+	26472758	K562	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	-1.7777526533321735	[458]	[112]	-7	hSpCas9	negative selection	701125
18913161	18913184	22	+	26627737	DLD1	viability	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	-0.5061892080614139	[142]	[29,35,28]	-5	hSpCas9	negative selection	816685
18922904	18922927	22	-	26627737	DLD1	viability	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.19428649698363532	[1113]	[419,571,235]	2	hSpCas9	negative selection	816686
18923132	18923155	22	-	26627737	DLD1	viability	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	0.2380526557835898	[803]	[176,282,410]	2	hSpCas9	negative selection	816687
18925186	18925209	22	-	26627737	DLD1	viability	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.7687009701998276	[252]	[105,178,122]	7	hSpCas9	negative selection	816688
18925693	18925716	22	-	26627737	DLD1	viability	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	0.018871155938906092	[174]	[56,40,65]	0	hSpCas9	negative selection	816689
18931031	18931054	22	+	26627737	DLD1	viability	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	-1.2812799565995403	[883]	[157,107,79]	-8	hSpCas9	negative selection	816690
18913161	18913184	22	+	26627737	GBM cells	viability after 5 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.19847415674459334	[12]	[11,3]	3	hSpCas9	negative selection	899000
18922904	18922927	22	-	26627737	GBM cells	viability after 5 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.13454212337882776	[495]	[295,287]	2	hSpCas9	negative selection	899001
18923132	18923155	22	-	26627737	GBM cells	viability after 5 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	0.431504198824864	[373]	[231,308]	6	hSpCas9	negative selection	899002
18925186	18925209	22	-	26627737	GBM cells	viability after 5 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.062412607168565254	[249]	[124,154]	1	hSpCas9	negative selection	899003
18925693	18925716	22	-	26627737	GBM cells	viability after 5 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-0.4031146625639719	[89]	[38,33]	-6	hSpCas9	negative selection	899004
18931031	18931054	22	+	26627737	GBM cells	viability after 5 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	-0.38602001251947515	[384]	[160,154]	-6	hSpCas9	negative selection	899005
18913161	18913184	22	+	26627737	GBM cells	viability after 13 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.4735789312582783	[12]	[11,7]	6	hSpCas9	negative selection	981315
18922904	18922927	22	-	26627737	GBM cells	viability after 13 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.27705792588610767	[495]	[383,278]	3	hSpCas9	negative selection	981316
18923132	18923155	22	-	26627737	GBM cells	viability after 13 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	-0.4089296413233865	[373]	[175,133]	-5	hSpCas9	negative selection	981317
18925186	18925209	22	-	26627737	GBM cells	viability after 13 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.06195134403983553	[249]	[161,124]	0	hSpCas9	negative selection	981318
18925693	18925716	22	-	26627737	GBM cells	viability after 13 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-0.19512691001566296	[89]	[40,43]	-2	hSpCas9	negative selection	981319
18931031	18931054	22	+	26627737	GBM cells	viability after 13 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	0.2439015019333146	[384]	[296,206]	3	hSpCas9	negative selection	981320
18913161	18913184	22	+	26627737	GBM cells	viability after 21 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.42434241646318194	[12]	[9,8]	4	hSpCas9	negative selection	1063630
18922904	18922927	22	-	26627737	GBM cells	viability after 21 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.176177467998619	[495]	[316,292]	1	hSpCas9	negative selection	1063631
18923132	18923155	22	-	26627737	GBM cells	viability after 21 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	-0.004724750742903794	[373]	[201,202]	0	hSpCas9	negative selection	1063632
18925186	18925209	22	-	26627737	GBM cells	viability after 21 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.07644863394385054	[249]	[149,136]	0	hSpCas9	negative selection	1063633
18925693	18925716	22	-	26627737	GBM cells	viability after 21 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	0.5093956042473495	[89]	[78,60]	5	hSpCas9	negative selection	1063634
18931031	18931054	22	+	26627737	GBM cells	viability after 21 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	0.010108618895955823	[384]	[230,191]	0	hSpCas9	negative selection	1063635
18913161	18913184	22	+	26627737	RPE1	viability after 9 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	-0.1417252501029913	[242]	[78,55]	-1	hSpCas9	negative selection	1145945
18922904	18922927	22	-	26627737	RPE1	viability after 9 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	-0.1518937069680072	[1656]	[269,720]	-1	hSpCas9	negative selection	1145946
18923132	18923155	22	-	26627737	RPE1	viability after 9 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	0.07401449934159177	[1318]	[366,521]	0	hSpCas9	negative selection	1145947
18925186	18925209	22	-	26627737	RPE1	viability after 9 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	-0.22050303049252995	[425]	[96,136]	-1	hSpCas9	negative selection	1145948
18925693	18925716	22	-	26627737	RPE1	viability after 9 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	1.426955610167309	[123]	[168,20]	7	hSpCas9	negative selection	1145949
18931031	18931054	22	+	26627737	RPE1	viability after 9 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	1.4956362333775695	[518]	[393,540]	8	hSpCas9	negative selection	1145950
18913161	18913184	22	+	26627737	RPE1	viability after 12 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.2667070826353437	[242]	[79,76]	1	hSpCas9	negative selection	1228260
18922904	18922927	22	-	26627737	RPE1	viability after 12 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	-0.2789472091295452	[1656]	[312,423]	-2	hSpCas9	negative selection	1228261
18923132	18923155	22	-	26627737	RPE1	viability after 12 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	0.07501904968400985	[1318]	[365,380]	0	hSpCas9	negative selection	1228262
18925186	18925209	22	-	26627737	RPE1	viability after 12 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	-0.38620986691952264	[425]	[106,66]	-3	hSpCas9	negative selection	1228263
18925693	18925716	22	-	26627737	RPE1	viability after 12 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	0.668279250368562	[123]	[101,0]	4	hSpCas9	negative selection	1228264
18931031	18931054	22	+	26627737	RPE1	viability after 12 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	1.305179953157738	[518]	[414,269]	7	hSpCas9	negative selection	1228265
18913161	18913184	22	+	26627737	RPE1	viability after 15 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	-0.5082746222287258	[242]	[57,38]	-3	hSpCas9	negative selection	1310575
18922904	18922927	22	-	26627737	RPE1	viability after 15 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	-0.2958468137619681	[1656]	[222,534]	-2	hSpCas9	negative selection	1310576
18923132	18923155	22	-	26627737	RPE1	viability after 15 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	0.030783902198603053	[1318]	[371,389]	0	hSpCas9	negative selection	1310577
18925186	18925209	22	-	26627737	RPE1	viability after 15 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	-0.5401646113010792	[425]	[61,102]	-3	hSpCas9	negative selection	1310578
18925693	18925716	22	-	26627737	RPE1	viability after 15 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-0.4278708657023498	[123]	[49,2]	-3	hSpCas9	negative selection	1310579
18931031	18931054	22	+	26627737	RPE1	viability after 15 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	1.3586468613517124	[518]	[432,321]	7	hSpCas9	negative selection	1310580
18913161	18913184	22	+	26627737	RPE1	viability after 18 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	-0.06864904263609906	[242]	[77,45]	0	hSpCas9	negative selection	1392890
18922904	18922927	22	-	26627737	RPE1	viability after 18 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.02363489259823992	[1656]	[295,623]	0	hSpCas9	negative selection	1392891
18923132	18923155	22	-	26627737	RPE1	viability after 18 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	-0.10894833181524277	[1318]	[331,327]	0	hSpCas9	negative selection	1392892
18925186	18925209	22	-	26627737	RPE1	viability after 18 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.17284889281537186	[425]	[146,110]	1	hSpCas9	negative selection	1392893
18925693	18925716	22	-	26627737	RPE1	viability after 18 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-0.36146095017521773	[123]	[41,8]	-2	hSpCas9	negative selection	1392894
18931031	18931054	22	+	26627737	RPE1	viability after 18 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	1.1999535579405223	[518]	[416,219]	6	hSpCas9	negative selection	1392895
18913161	18913184	22	+	26627737	HeLa	viability after 8 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	-0.42206453435042735	[871]	[361,207,295]	-4	hSpCas9	negative selection	1475205
18922904	18922927	22	-	26627737	HeLa	viability after 8 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.9496771789537315	[473]	[458,388,362]	7	hSpCas9	negative selection	1475206
18923132	18923155	22	-	26627737	HeLa	viability after 8 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	1.2186957132300513	[377]	[445,550,179]	8	hSpCas9	negative selection	1475207
18925186	18925209	22	-	26627737	HeLa	viability after 8 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	-0.2942011175305309	[237]	[74,131,46]	-3	hSpCas9	negative selection	1475208
18925693	18925716	22	-	26627737	HeLa	viability after 8 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-0.4222247149467667	[205]	[55,85,56]	-4	hSpCas9	negative selection	1475209
18931031	18931054	22	+	26627737	HeLa	viability after 8 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	-0.3201451476860011	[497]	[175,167,176]	-3	hSpCas9	negative selection	1475210
18913161	18913184	22	+	26627737	HeLa	viability after 12 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	-0.23130697819668444	[871]	[184,357,368]	-2	hSpCas9	negative selection	1557520
18922904	18922927	22	-	26627737	HeLa	viability after 12 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.8964346235533927	[473]	[388,294,417]	7	hSpCas9	negative selection	1557521
18923132	18923155	22	-	26627737	HeLa	viability after 12 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	-0.1188584793764765	[377]	[176,148,105]	-1	hSpCas9	negative selection	1557522
18925186	18925209	22	-	26627737	HeLa	viability after 12 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.06586189139266108	[237]	[129,108,69]	0	hSpCas9	negative selection	1557523
18925693	18925716	22	-	26627737	HeLa	viability after 12 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-1.8172710169940451	[205]	[0,59,6]	-9	hSpCas9	negative selection	1557524
18931031	18931054	22	+	26627737	HeLa	viability after 12 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	-0.09922582890588694	[497]	[124,148,304]	-1	hSpCas9	negative selection	1557525
18913161	18913184	22	+	26627737	HeLa	viability after 15 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.3760122378778352	[871]	[398,412,579]	3	hSpCas9	negative selection	1639835
18922904	18922927	22	-	26627737	HeLa	viability after 15 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.8098446453152934	[473]	[226,429,360]	6	hSpCas9	negative selection	1639836
18923132	18923155	22	-	26627737	HeLa	viability after 15 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	0.7020787169598258	[377]	[241,320,182]	5	hSpCas9	negative selection	1639837
18925186	18925209	22	-	26627737	HeLa	viability after 15 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	-0.011873967162772114	[237]	[137,110,33]	0	hSpCas9	negative selection	1639838
18925693	18925716	22	-	26627737	HeLa	viability after 15 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-0.6481476013051498	[205]	[63,83,8]	-5	hSpCas9	negative selection	1639839
18931031	18931054	22	+	26627737	HeLa	viability after 15 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	0.1496082286912367	[497]	[101,279,299]	1	hSpCas9	negative selection	1639840
18913161	18913184	22	+	26627737	HeLa	viability after 18 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.3524841937122938	[871]	[245,350,579]	3	hSpCas9	negative selection	1722150
18922904	18922927	22	-	26627737	HeLa	viability after 18 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.7954104814671119	[473]	[148,351,360]	6	hSpCas9	negative selection	1722151
18923132	18923155	22	-	26627737	HeLa	viability after 18 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	0.7167836841952461	[377]	[163,269,182]	5	hSpCas9	negative selection	1722152
18925186	18925209	22	-	26627737	HeLa	viability after 18 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.05506879200251691	[237]	[98,94,33]	0	hSpCas9	negative selection	1722153
18925693	18925716	22	-	26627737	HeLa	viability after 18 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-0.66747592420999	[205]	[41,68,8]	-5	hSpCas9	negative selection	1722154
18931031	18931054	22	+	26627737	HeLa	viability after 18 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	0.15580694499914444	[497]	[70,230,299]	1	hSpCas9	negative selection	1722155
18913161	18913184	22	+	26627737	HCT116	viability after 6 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	-1.1048393602648632	[751]	[121,17]	-6	hSpCas9	negative selection	1804465
18922904	18922927	22	-	26627737	HCT116	viability after 6 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.9937554888434089	[982]	[163,386]	5	hSpCas9	negative selection	1804466
18923132	18923155	22	-	26627737	HCT116	viability after 6 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	0.7729375620510623	[706]	[138,217]	4	hSpCas9	negative selection	1804467
18925186	18925209	22	-	26627737	HCT116	viability after 6 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	-1.9608687262057682	[579]	[25,21]	-8	hSpCas9	negative selection	1804468
18925693	18925716	22	-	26627737	HCT116	viability after 6 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-2.8044013807368424	[154]	[7,0]	-9	hSpCas9	negative selection	1804469
18931031	18931054	22	+	26627737	HCT116	viability after 6 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	1.4932847466430803	[666]	[679,82]	7	hSpCas9	negative selection	1804470
18913161	18913184	22	+	26627737	HCT116	viability after 8 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.16451507287632539	[606]	[445,313,365]	2	hSpCas9	negative selection	1886780
18922904	18922927	22	-	26627737	HCT116	viability after 8 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	-0.6537103885815226	[869]	[234,461,216]	-7	hSpCas9	negative selection	1886781
18923132	18923155	22	-	26627737	HCT116	viability after 8 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	-0.02762113201649985	[519]	[233,371,236]	0	hSpCas9	negative selection	1886782
18925186	18925209	22	-	26627737	HCT116	viability after 8 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.6795304557562146	[121]	[79,174,67]	6	hSpCas9	negative selection	1886783
18925693	18925716	22	-	26627737	HCT116	viability after 8 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	0.5225588912600377	[109]	[68,113,77]	5	hSpCas9	negative selection	1886784
18931031	18931054	22	+	26627737	HCT116	viability after 8 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	0.5754141544885245	[227]	[135,178,244]	6	hSpCas9	negative selection	1886785
18913161	18913184	22	+	26627737	HCT116	viability after 9 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	-0.7831276363717088	[751]	[133,102]	-5	hSpCas9	negative selection	1969095
18922904	18922927	22	-	26627737	HCT116	viability after 9 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.3512997774715897	[982]	[383,295]	2	hSpCas9	negative selection	1969096
18923132	18923155	22	-	26627737	HCT116	viability after 9 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	0.17541387729303135	[706]	[301,142]	1	hSpCas9	negative selection	1969097
18925186	18925209	22	-	26627737	HCT116	viability after 9 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	-2.902544394293392	[579]	[32,10]	-9	hSpCas9	negative selection	1969098
18925693	18925716	22	-	26627737	HCT116	viability after 9 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-3.3390019729799594	[154]	[7,0]	-9	hSpCas9	negative selection	1969099
18931031	18931054	22	+	26627737	HCT116	viability after 9 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	1.2150489270932059	[666]	[389,431]	7	hSpCas9	negative selection	1969100
18913161	18913184	22	+	26627737	HCT116	viability after 12 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.25148387265763716	[606]	[377,322,436]	2	hSpCas9	negative selection	2051410
18922904	18922927	22	-	26627737	HCT116	viability after 12 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	-1.1306483750879521	[869]	[242,190,188]	-8	hSpCas9	negative selection	2051411
18923132	18923155	22	-	26627737	HCT116	viability after 12 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	0.18605001940870036	[519]	[301,374,257]	2	hSpCas9	negative selection	2051412
18925186	18925209	22	-	26627737	HCT116	viability after 12 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.5902629320947675	[121]	[90,93,104]	5	hSpCas9	negative selection	2051413
18925693	18925716	22	-	26627737	HCT116	viability after 12 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-0.007124318833610976	[109]	[65,105,0]	0	hSpCas9	negative selection	2051414
18931031	18931054	22	+	26627737	HCT116	viability after 12 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	0.4275620308076618	[227]	[112,173,200]	4	hSpCas9	negative selection	2051415
18913161	18913184	22	+	26627737	HCT116	viability after 15 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.1548919223689469	[606]	[490,310,374]	1	hSpCas9	negative selection	2133725
18922904	18922927	22	-	26627737	HCT116	viability after 15 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	-0.6952988519922226	[869]	[363,305,262]	-6	hSpCas9	negative selection	2133726
18923132	18923155	22	-	26627737	HCT116	viability after 15 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	-0.12287650934628502	[519]	[252,361,205]	-1	hSpCas9	negative selection	2133727
18925186	18925209	22	-	26627737	HCT116	viability after 15 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.4780093519928076	[121]	[144,94,58]	4	hSpCas9	negative selection	2133728
18925693	18925716	22	-	26627737	HCT116	viability after 15 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	0.10822110839036969	[109]	[74,51,77]	1	hSpCas9	negative selection	2133729
18931031	18931054	22	+	26627737	HCT116	viability after 15 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	0.6853263965681181	[227]	[325,214,105]	6	hSpCas9	negative selection	2133730
18913161	18913184	22	+	26627737	HCT116	viability after 18 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	-0.060920945372328505	[606]	[341,238,264]	0	hSpCas9	negative selection	2216040
18922904	18922927	22	-	26627737	HCT116	viability after 18 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	-1.4604371107209304	[869]	[171,157,126]	-8	hSpCas9	negative selection	2216041
18923132	18923155	22	-	26627737	HCT116	viability after 18 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	-0.046711114517845154	[519]	[169,291,265]	0	hSpCas9	negative selection	2216042
18925186	18925209	22	-	26627737	HCT116	viability after 18 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.7684467916073952	[121]	[64,109,126]	6	hSpCas9	negative selection	2216043
18925693	18925716	22	-	26627737	HCT116	viability after 18 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	0.6582489728173025	[109]	[71,163,6]	5	hSpCas9	negative selection	2216044
18931031	18931054	22	+	26627737	HCT116	viability after 18 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	1.001059549041758	[227]	[209,197,256]	7	hSpCas9	negative selection	2216045
18933694	18933717	22	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCACCATGCCTAG	PRODH	ENSG00000100033	0.3888402363631881	[40,30]	[14,4]	1	dCas9-VP64	positive selection	2384347
18936527	18936550	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTCTGTTGCTGTCTTCACGG	PRODH	ENSG00000100033	0.6488060322561577	[193,244]	[69,80]	2	dCas9-VP64	positive selection	2409282
18936511	18936534	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCACGGAGAGCAGGAGCAGAGG	PRODH	ENSG00000100033	-2.920734549358797	[321,94]	[7,1]	-9	dCas9-VP64	positive selection	2409285
18933694	18933717	22	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCACCATGCCTAG	PRODH	ENSG00000100033	0.501495088189527	[102,55]	[55,18]	4	dCas9-VP64	positive selection	2479602
18936527	18936550	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTCTGTTGCTGTCTTCACGG	PRODH	ENSG00000100033	-0.049968831351896004	[415,456]	[67,202]	0	dCas9-VP64	positive selection	2504537
18936511	18936534	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCACGGAGAGCAGGAGCAGAGG	PRODH	ENSG00000100033	-0.5940388167472266	[106,185]	[33,27]	-6	dCas9-VP64	positive selection	2504540
18925107	18925130	22	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTGGCGTAGAAGTAGGTGCGGG	PRODH	ENSG00000100033	0.4227159155372683	[2,2]	[3,2]	8	hSpCas9	positive selection	3013798
18923130	18923153	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCATTAAGCTCACAGCACTGGGG	PRODH	ENSG00000100033	-0.6603734781070163	[2,2]	[2,0]	-7	hSpCas9	positive selection	3013799
18931012	18931035	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGGAGGACCTGAGCCCCGAGG	PRODH	ENSG00000100033	-1.0469003030012836	[2,2]	[0,0]	-9	hSpCas9	positive selection	3013800
18922918	18922941	22	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTGCAGCTGCAGTTCTCAGAGG	PRODH	ENSG00000100033	0.14990030704525859	[5,5]	[5,4]	3	hSpCas9	positive selection	3013801
18925107	18925130	22	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTGGCGTAGAAGTAGGTGCGGG	PRODH	ENSG00000100033	0.24065532505071652	[2,2]	[2,1]	4	hSpCas9	positive selection	3081656
18923130	18923153	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCATTAAGCTCACAGCACTGGGG	PRODH	ENSG00000100033	-0.510818694144734	[2,2]	[2,0]	-7	hSpCas9	positive selection	3081657
18931012	18931035	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGGAGGACCTGAGCCCCGAGG	PRODH	ENSG00000100033	-0.3453458751147237	[2,2]	[1,0]	-5	hSpCas9	positive selection	3081658
18922918	18922941	22	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTGCAGCTGCAGTTCTCAGAGG	PRODH	ENSG00000100033	0.4415333683275697	[5,5]	[6,4]	7	hSpCas9	positive selection	3081659
18925703	18925726		-	24336571	A375	resistance to PLX after 7 days	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	0.10514226188123063	[15,12]	[15,14]	3	hSpCas9	positive selection	3137921
18925692	18925715		+	24336571	A375	resistance to PLX after 7 days	GCCATCCCTCTCCGCAGCTGAGG	PRODH	ENSG00000100033	0.13169696713804102	[30,28]	[33,30]	4	hSpCas9	positive selection	3137922
18922831	18922854		-	24336571	A375	resistance to PLX after 7 days	TGCCATGGACACCAAGCTGGAGG	PRODH	ENSG00000100033	0.250614725752764	[25,26]	[30,30]	7	hSpCas9	positive selection	3137923
18925703	18925726		-	24336571	A375	resistance to PLX after 14 days	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	0.16188378878137677	[8,9]	[4,3]	1	hSpCas9	positive selection	3195714
18925692	18925715		+	24336571	A375	resistance to PLX after 14 days	GCCATCCCTCTCCGCAGCTGAGG	PRODH	ENSG00000100033	1.7039017241616117	[20,33]	[34,47]	9	hSpCas9	positive selection	3195715
18922831	18922854		-	24336571	A375	resistance to PLX after 14 days	TGCCATGGACACCAAGCTGGAGG	PRODH	ENSG00000100033	2.9808408505934487	[21,27]	[140,45]	9	hSpCas9	positive selection	3195716
18925703	18925726		-	24336571	A375	viability after 7 days	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.6073641401430662	[23]	[15,12]	-7	hSpCas9	negative selection	3253507
18925692	18925715		+	24336571	A375	viability after 7 days	GCCATCCCTCTCCGCAGCTGAGG	PRODH	ENSG00000100033	0.1352664608000056	[28]	[30,28]	2	hSpCas9	negative selection	3253508
18922831	18922854		-	24336571	A375	viability after 7 days	TGCCATGGACACCAAGCTGGAGG	PRODH	ENSG00000100033	0.14891894706312858	[24]	[25,26]	2	hSpCas9	negative selection	3253509
18925703	18925726		-	24336571	A375	viability after 14 days	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-1.1463853342577444	[23]	[8,9]	-9	hSpCas9	negative selection	3311300
18925692	18925715		+	24336571	A375	viability after 14 days	GCCATCCCTCTCCGCAGCTGAGG	PRODH	ENSG00000100033	0.015337671155938981	[28]	[20,33]	0	hSpCas9	negative selection	3311301
18922831	18922854		-	24336571	A375	viability after 14 days	TGCCATGGACACCAAGCTGGAGG	PRODH	ENSG00000100033	0.09335741107282414	[24]	[21,27]	1	hSpCas9	negative selection	3311302
18922867	18922890	22	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCCCTTGCTCCACAGCCATTTGG	PRODH	ENSG00000100033	-1.504225020998644	[433,433]	[0,0]	-8	hSpCas9	positive selection	3387594
18922882	18922905	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGGTGCTTCTTTCACCAAATGG	PRODH	ENSG00000100033	0.3384629741712407	[120,120]	[0,0]	1	hSpCas9	positive selection	3387595
18925703	18925726	22	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.4908666381436253	[214,214]	[0,0]	-3	hSpCas9	positive selection	3387596
18925106	18925129	22	+	26780180	HT29	viability (Avana library 4 designs)	ATTGGCGTAGAAGTAGGTGCGGG	PRODH	ENSG00000100033	1.64678501444345	[]	[]	6	hSpCas9	negative selection	3451993
18923130	18923153	22	-	26780180	HT29	viability (Avana library 4 designs)	CCATTAAGCTCACAGCACTGGGG	PRODH	ENSG00000100033	0.635917847949663	[]	[]	2	hSpCas9	negative selection	3451994
18931012	18931035	22	-	26780180	HT29	viability (Avana library 4 designs)	GGAGGAGGACCTGAGCCCCGAGG	PRODH	ENSG00000100033	3.64792398507053	[]	[]	9	hSpCas9	negative selection	3451995
18922918	18922941	22	-	26780180	HT29	viability (Avana library 4 designs)	TTTGCAGCTGCAGTTCTCAGAGG	PRODH	ENSG00000100033	-0.242318234516652	[]	[]	-4	hSpCas9	negative selection	3451996
18925106	18925129	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTGGCGTAGAAGTAGGTGCGGG	PRODH	ENSG00000100033	3.20922502684476	[]	[]	5	hSpCas9	negative selection	3548150
18931012	18931035	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGGAGGACCTGAGCCCCGAGG	PRODH	ENSG00000100033	-7.79231317252811	[]	[]	-7	hSpCas9	negative selection	3548151
18922918	18922941	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGCAGCTGCAGTTCTCAGAGG	PRODH	ENSG00000100033	4.86510419388236	[]	[]	8	hSpCas9	negative selection	3548152
18923130	18923153	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCATTAAGCTCACAGCACTGGGG	PRODH	ENSG00000100033	-4.60987673769425	[]	[]	-5	hSpCas9	negative selection	3548153
18930997	18931020	22	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTGTGCTCTGCCTCCTCGGGG	PRODH	ENSG00000100033	4.79167510907143	[]	[]	7	hSpCas9	negative selection	3548154
18931069	18931092	22	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCCTGCTTCGGCACTACAGGG	PRODH	ENSG00000100033	4.83867808372945	[]	[]	8	hSpCas9	negative selection	3548155
18925106	18925129	22	+	26780180	A375	viability (Avana lentiGuide)	ATTGGCGTAGAAGTAGGTGCGGG	PRODH	ENSG00000100033	1.3383466915434	[]	[]	1	hSpCas9	negative selection	3656809
18931012	18931035	22	-	26780180	A375	viability (Avana lentiGuide)	GGAGGAGGACCTGAGCCCCGAGG	PRODH	ENSG00000100033	24.9493097533421	[]	[]	9	hSpCas9	negative selection	3656810
18922918	18922941	22	-	26780180	A375	viability (Avana lentiGuide)	TTTGCAGCTGCAGTTCTCAGAGG	PRODH	ENSG00000100033	-3.73602876547859	[]	[]	-6	hSpCas9	negative selection	3656811
18923130	18923153	22	-	26780180	A375	viability (Avana lentiGuide)	CCATTAAGCTCACAGCACTGGGG	PRODH	ENSG00000100033	-0.896946960570988	[]	[]	-1	hSpCas9	negative selection	3656812
18930997	18931020	22	+	26780180	A375	viability (Avana lentiGuide)	CCTTGTGCTCTGCCTCCTCGGGG	PRODH	ENSG00000100033	0.0731314894012658	[]	[]	0	hSpCas9	negative selection	3656813
18931069	18931092	22	-	26780180	A375	viability (Avana lentiGuide)	GCCCCTGCTTCGGCACTACAGGG	PRODH	ENSG00000100033	-7.37783766299052	[]	[]	-9	hSpCas9	negative selection	3656814
18925106	18925129	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTGGCGTAGAAGTAGGTGCGGG	PRODH	ENSG00000100033	0.0985036875085158	[5]	[5,5]	2	hSpCas9	positive selection	3765416
18931012	18931035	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGGAGGACCTGAGCCCCGAGG	PRODH	ENSG00000100033	-0.9642947450272945	[4]	[0,2]	-8	hSpCas9	positive selection	3765417
18922918	18922941	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGCAGCTGCAGTTCTCAGAGG	PRODH	ENSG00000100033	0.1837204983366466	[6]	[7,6]	5	hSpCas9	positive selection	3765418
18923130	18923153	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATTAAGCTCACAGCACTGGGG	PRODH	ENSG00000100033	-0.4864615645549082	[4]	[2,2]	-6	hSpCas9	positive selection	3765419
18930997	18931020	22	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTGTGCTCTGCCTCCTCGGGG	PRODH	ENSG00000100033	0.33934368732902676	[5]	[6,5]	8	hSpCas9	positive selection	3765420
18931069	18931092	22	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCCTGCTTCGGCACTACAGGG	PRODH	ENSG00000100033	0.12292794920404722	[4]	[4,4]	3	hSpCas9	positive selection	3765421
18925106	18925129	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTGGCGTAGAAGTAGGTGCGGG	PRODH	ENSG00000100033	0.2440423904368308	[5]	[5,5]	6	hSpCas9	positive selection	3874023
18931012	18931035	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGGAGGACCTGAGCCCCGAGG	PRODH	ENSG00000100033	-1.0994135678756696	[5]	[3,0]	-8	hSpCas9	positive selection	3874024
18922918	18922941	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGCAGCTGCAGTTCTCAGAGG	PRODH	ENSG00000100033	0.31334030620641246	[7]	[7,7]	8	hSpCas9	positive selection	3874025
18923130	18923153	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATTAAGCTCACAGCACTGGGG	PRODH	ENSG00000100033	-0.3379338127673737	[4]	[1,3]	-4	hSpCas9	positive selection	3874026
18930997	18931020	22	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTGTGCTCTGCCTCCTCGGGG	PRODH	ENSG00000100033	0.3523094562784104	[5]	[4,6]	9	hSpCas9	positive selection	3874027
18931069	18931092	22	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCCTGCTTCGGCACTACAGGG	PRODH	ENSG00000100033	0.3417344197352863	[5]	[6,4]	8	hSpCas9	positive selection	3874028
18918370	18918393	22	-	26780180	A375	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	1.43253877910517	[]	[]	8	hSpCas9	negative selection	3984495
18918370	18918393	22	-	26780180	HT29	viability (GeCKOv2 library)	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	2.3134937563178	[]	[]	9	hSpCas9	negative selection	4092461
18925692	18925715	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCATCCCTCTCCGCAGCTGAGG	PRODH	ENSG00000100033	0.32308586594232735	[4]	[3,5]	7	hSpCas9	positive selection	4163094
18922831	18922854	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCCATGGACACCAAGCTGGAGG	PRODH	ENSG00000100033	0.5362994577969249	[4]	[3,6]	9	hSpCas9	positive selection	4163095
18925692	18925715	22	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCATCCCTCTCCGCAGCTGAGG	PRODH	ENSG00000100033	0.16304152387983106	[4]	[4,3,2,0]	1	hSpCas9	positive selection	4227116
18922831	18922854	22	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCCATGGACACCAAGCTGGAGG	PRODH	ENSG00000100033	1.097821842483679	[4]	[4,2,3,4]	8	hSpCas9	positive selection	4227117
18918370	18918393	22	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.0004289968067160213	[3]	[2,1]	0	hSpCas9	positive selection	4292294
18925149	18925171	22	+	27760321	OCIAML3	viability	CGGTCCCCGAAGGCCCAGTGGG	PRODH	ENSG00000100033	0.43875949440679274	[576,514]	[633,504]	5	hSpCas9	negative selection	4430775
18925171	18925193	22	-	27760321	OCIAML3	viability	AAGCGGGACAAGCAATACCAGG	PRODH	ENSG00000100033	0.025158514012514788	[382,278]	[302,205]	0	hSpCas9	negative selection	4430776
18922355	18922377	22	+	27760321	OCIAML3	viability	CAGTCCTCAATCTCAGCCCTGG	PRODH	ENSG00000100033	-0.5555238061741936	[947,756]	[374,549]	-5	hSpCas9	negative selection	4430777
18922386	18922408	22	-	27760321	OCIAML3	viability	AAGGAAAGTGTCGCAAAGTTGG	PRODH	ENSG00000100033	0.7753336953450956	[158,153]	[149,287]	8	hSpCas9	negative selection	4430778
18923103	18923125	22	+	27760321	OCIAML3	viability	TCTAGCACTTACCAGAAACTGG	PRODH	ENSG00000100033	-1.5200849796966693	[171,191]	[59,36]	-8	hSpCas9	negative selection	4430779
18925149	18925171	22	+	27760321	OCIAML2	viability	CGGTCCCCGAAGGCCCAGTGGG	PRODH	ENSG00000100033	0.10887101422369033	[576,514]	[337,656]	1	hSpCas9	negative selection	4514238
18925171	18925193	22	-	27760321	OCIAML2	viability	AAGCGGGACAAGCAATACCAGG	PRODH	ENSG00000100033	-0.44648782316687924	[382,278]	[147,255]	-5	hSpCas9	negative selection	4514239
18922355	18922377	22	+	27760321	OCIAML2	viability	CAGTCCTCAATCTCAGCCCTGG	PRODH	ENSG00000100033	-0.6177531182066267	[947,756]	[375,539]	-6	hSpCas9	negative selection	4514240
18922386	18922408	22	-	27760321	OCIAML2	viability	AAGGAAAGTGTCGCAAAGTTGG	PRODH	ENSG00000100033	0.999837761451994	[158,153]	[175,355]	9	hSpCas9	negative selection	4514241
18923103	18923125	22	+	27760321	OCIAML2	viability	TCTAGCACTTACCAGAAACTGG	PRODH	ENSG00000100033	0.8521883555137804	[171,191]	[225,322]	9	hSpCas9	negative selection	4514242
18925149	18925171	22	+	27760321	MV411	viability	CGGTCCCCGAAGGCCCAGTGGG	PRODH	ENSG00000100033	0.19824621755063965	[576,514]	[425,392]	1	hSpCas9	negative selection	4597701
18925171	18925193	22	-	27760321	MV411	viability	AAGCGGGACAAGCAATACCAGG	PRODH	ENSG00000100033	0.015055034997250138	[382,278]	[214,223]	0	hSpCas9	negative selection	4597702
18922355	18922377	22	+	27760321	MV411	viability	CAGTCCTCAATCTCAGCCCTGG	PRODH	ENSG00000100033	-0.5400388254274422	[947,756]	[165,712]	-4	hSpCas9	negative selection	4597703
18922386	18922408	22	-	27760321	MV411	viability	AAGGAAAGTGTCGCAAAGTTGG	PRODH	ENSG00000100033	0.10310636369592419	[158,153]	[43,211]	0	hSpCas9	negative selection	4597704
18923103	18923125	22	+	27760321	MV411	viability	TCTAGCACTTACCAGAAACTGG	PRODH	ENSG00000100033	0.6938170628214395	[171,191]	[178,220]	5	hSpCas9	negative selection	4597705
18925149	18925171	22	+	27760321	HL60	viability	CGGTCCCCGAAGGCCCAGTGGG	PRODH	ENSG00000100033	0.4775232390251738	[576,514]	[558,684]	6	hSpCas9	negative selection	4681164
18925171	18925193	22	-	27760321	HL60	viability	AAGCGGGACAAGCAATACCAGG	PRODH	ENSG00000100033	-0.5568187454799949	[382,278]	[199,162]	-6	hSpCas9	negative selection	4681165
18922355	18922377	22	+	27760321	HL60	viability	CAGTCCTCAATCTCAGCCCTGG	PRODH	ENSG00000100033	-0.4972012023204772	[947,756]	[455,526]	-5	hSpCas9	negative selection	4681166
18922386	18922408	22	-	27760321	HL60	viability	AAGGAAAGTGTCGCAAAGTTGG	PRODH	ENSG00000100033	0.5138212880193802	[158,153]	[195,168]	6	hSpCas9	negative selection	4681167
18923103	18923125	22	+	27760321	HL60	viability	TCTAGCACTTACCAGAAACTGG	PRODH	ENSG00000100033	-1.0007046752618254	[171,191]	[103,43]	-7	hSpCas9	negative selection	4681168
18925149	18925171	22	+	27760321	HT1080	viability	CGGTCCCCGAAGGCCCAGTGGG	PRODH	ENSG00000100033	-2.7676134529255125	[514,401]	[1,53]	-7	hSpCas9	negative selection	4764627
18925171	18925193	22	-	27760321	HT1080	viability	AAGCGGGACAAGCAATACCAGG	PRODH	ENSG00000100033	-3.687731715477288	[278,217]	[0,14]	-8	hSpCas9	negative selection	4764628
18922355	18922377	22	+	27760321	HT1080	viability	CAGTCCTCAATCTCAGCCCTGG	PRODH	ENSG00000100033	-0.6709143828749999	[756,590]	[76,268]	-3	hSpCas9	negative selection	4764629
18922386	18922408	22	-	27760321	HT1080	viability	AAGGAAAGTGTCGCAAAGTTGG	PRODH	ENSG00000100033	1.6886732480009872	[153,119]	[268,73]	8	hSpCas9	negative selection	4764630
18923103	18923125	22	+	27760321	HT1080	viability	TCTAGCACTTACCAGAAACTGG	PRODH	ENSG00000100033	1.8812378980792408	[191,149]	[302,193]	8	hSpCas9	negative selection	4764631
18925149	18925171	22	+	27760321	HT29	viability after 7 days	CGGTCCCCGAAGGCCCAGTGGG	PRODH	ENSG00000100033	-0.09255154322285009	[514,401]	[535,457,657]	-1	hSpCas9	negative selection	4848090
18925171	18925193	22	-	27760321	HT29	viability after 7 days	AAGCGGGACAAGCAATACCAGG	PRODH	ENSG00000100033	-0.048271712355966945	[278,217]	[421,316,206]	0	hSpCas9	negative selection	4848091
18922355	18922377	22	+	27760321	HT29	viability after 7 days	CAGTCCTCAATCTCAGCCCTGG	PRODH	ENSG00000100033	0.11483425511158285	[756,590]	[917,830,1057]	1	hSpCas9	negative selection	4848092
18922386	18922408	22	-	27760321	HT29	viability after 7 days	AAGGAAAGTGTCGCAAAGTTGG	PRODH	ENSG00000100033	-0.004381586272300009	[153,119]	[268,163,108]	0	hSpCas9	negative selection	4848093
18923103	18923125	22	+	27760321	HT29	viability after 7 days	TCTAGCACTTACCAGAAACTGG	PRODH	ENSG00000100033	-0.13419439032203218	[191,149]	[226,191,185]	-2	hSpCas9	negative selection	4848094
18925149	18925171	22	+	27760321	HT29	viability after 25 days	CGGTCCCCGAAGGCCCAGTGGG	PRODH	ENSG00000100033	0.25599591518471765	[514,401]	[588,590,706]	2	hSpCas9	negative selection	4931553
18925171	18925193	22	-	27760321	HT29	viability after 25 days	AAGCGGGACAAGCAATACCAGG	PRODH	ENSG00000100033	-0.18578203103023094	[278,217]	[469,73,183]	-2	hSpCas9	negative selection	4931554
18922355	18922377	22	+	27760321	HT29	viability after 25 days	CAGTCCTCAATCTCAGCCCTGG	PRODH	ENSG00000100033	-0.6253184594208334	[756,590]	[482,380,649]	-5	hSpCas9	negative selection	4931555
18922386	18922408	22	-	27760321	HT29	viability after 25 days	AAGGAAAGTGTCGCAAAGTTGG	PRODH	ENSG00000100033	0.3783393744077024	[153,119]	[252,150,202]	4	hSpCas9	negative selection	4931556
18923103	18923125	22	+	27760321	HT29	viability after 25 days	TCTAGCACTTACCAGAAACTGG	PRODH	ENSG00000100033	0.007292068002875851	[191,149]	[336,64,175]	0	hSpCas9	negative selection	4931557
18925149	18925171	22	+	27760321	HT29	viability after 22 days	CGGTCCCCGAAGGCCCAGTGGG	PRODH	ENSG00000100033	0.019913916994165615	[514,401]	[316,679,621]	0	hSpCas9	negative selection	5015016
18925171	18925193	22	-	27760321	HT29	viability after 22 days	AAGCGGGACAAGCAATACCAGG	PRODH	ENSG00000100033	-0.18154886270723336	[278,217]	[278,255,223]	-2	hSpCas9	negative selection	5015017
18922355	18922377	22	+	27760321	HT29	viability after 22 days	CAGTCCTCAATCTCAGCCCTGG	PRODH	ENSG00000100033	-0.47855006351126195	[756,590]	[535,507,634]	-4	hSpCas9	negative selection	5015018
18922386	18922408	22	-	27760321	HT29	viability after 22 days	AAGGAAAGTGTCGCAAAGTTGG	PRODH	ENSG00000100033	0.11791840646319685	[153,119]	[183,181,148]	1	hSpCas9	negative selection	5015019
18923103	18923125	22	+	27760321	HT29	viability after 22 days	TCTAGCACTTACCAGAAACTGG	PRODH	ENSG00000100033	-0.13030905231272372	[191,149]	[226,91,221]	-1	hSpCas9	negative selection	5015020
18925149	18925171	22	+	27760321	HT29	viability after 19 days	CGGTCCCCGAAGGCCCAGTGGG	PRODH	ENSG00000100033	-0.04329893235527388	[514,401]	[362,745,405]	0	hSpCas9	negative selection	5098479
18925171	18925193	22	-	27760321	HT29	viability after 19 days	AAGCGGGACAAGCAATACCAGG	PRODH	ENSG00000100033	-1.2808744731699941	[278,217]	[174,120,62]	-7	hSpCas9	negative selection	5098480
18922355	18922377	22	+	27760321	HT29	viability after 19 days	CAGTCCTCAATCTCAGCCCTGG	PRODH	ENSG00000100033	-0.7867204362053114	[756,590]	[596,367,392]	-6	hSpCas9	negative selection	5098481
18922386	18922408	22	-	27760321	HT29	viability after 19 days	AAGGAAAGTGTCGCAAAGTTGG	PRODH	ENSG00000100033	0.12810849209532216	[153,119]	[212,162,142]	1	hSpCas9	negative selection	5098482
18923103	18923125	22	+	27760321	HT29	viability after 19 days	TCTAGCACTTACCAGAAACTGG	PRODH	ENSG00000100033	-0.11297701512481129	[191,149]	[309,12,230]	-1	hSpCas9	negative selection	5098483
18925149	18925171	22	+	27760321	HT29	viability after 16 days	CGGTCCCCGAAGGCCCAGTGGG	PRODH	ENSG00000100033	0.3823507230394041	[514,401]	[743,436,837]	4	hSpCas9	negative selection	5181942
18925171	18925193	22	-	27760321	HT29	viability after 16 days	AAGCGGGACAAGCAATACCAGG	PRODH	ENSG00000100033	0.17689628431673576	[278,217]	[437,297,218]	2	hSpCas9	negative selection	5181943
18922355	18922377	22	+	27760321	HT29	viability after 16 days	CAGTCCTCAATCTCAGCCCTGG	PRODH	ENSG00000100033	-0.6395783880110654	[756,590]	[704,481,285]	-6	hSpCas9	negative selection	5181944
18922386	18922408	22	-	27760321	HT29	viability after 16 days	AAGGAAAGTGTCGCAAAGTTGG	PRODH	ENSG00000100033	-0.13527736516699806	[153,119]	[151,92,175]	-1	hSpCas9	negative selection	5181945
18923103	18923125	22	+	27760321	HT29	viability after 16 days	TCTAGCACTTACCAGAAACTGG	PRODH	ENSG00000100033	-0.14308596335162305	[191,149]	[271,99,158]	-1	hSpCas9	negative selection	5181946
18925149	18925171	22	+	27760321	HT29	viability after 13 days	CGGTCCCCGAAGGCCCAGTGGG	PRODH	ENSG00000100033	0.7168159296840918	[514,401]	[926,1018,687]	8	hSpCas9	negative selection	5265405
18925171	18925193	22	-	27760321	HT29	viability after 13 days	AAGCGGGACAAGCAATACCAGG	PRODH	ENSG00000100033	0.4076628807888831	[278,217]	[474,441,238]	5	hSpCas9	negative selection	5265406
18922355	18922377	22	+	27760321	HT29	viability after 13 days	CAGTCCTCAATCTCAGCCCTGG	PRODH	ENSG00000100033	-0.2879834871070234	[756,590]	[771,663,493]	-4	hSpCas9	negative selection	5265407
18922386	18922408	22	-	27760321	HT29	viability after 13 days	AAGGAAAGTGTCGCAAAGTTGG	PRODH	ENSG00000100033	0.4446276480835707	[153,119]	[325,130,192]	5	hSpCas9	negative selection	5265408
18923103	18923125	22	+	27760321	HT29	viability after 13 days	TCTAGCACTTACCAGAAACTGG	PRODH	ENSG00000100033	-0.33209074615998047	[191,149]	[205,114,151]	-4	hSpCas9	negative selection	5265409
18925149	18925171	22	+	27760321	HT29	viability after 10 days	CGGTCCCCGAAGGCCCAGTGGG	PRODH	ENSG00000100033	0.024269139165790765	[514,401]	[640,546,557]	0	hSpCas9	negative selection	5348868
18925171	18925193	22	-	27760321	HT29	viability after 10 days	AAGCGGGACAAGCAATACCAGG	PRODH	ENSG00000100033	-0.1723997384702195	[278,217]	[214,342,269]	-2	hSpCas9	negative selection	5348869
18922355	18922377	22	+	27760321	HT29	viability after 10 days	CAGTCCTCAATCTCAGCCCTGG	PRODH	ENSG00000100033	-0.32029999355556305	[756,590]	[645,648,724]	-4	hSpCas9	negative selection	5348870
18922386	18922408	22	-	27760321	HT29	viability after 10 days	AAGGAAAGTGTCGCAAAGTTGG	PRODH	ENSG00000100033	-0.5757048571357362	[153,119]	[66,110,164]	-6	hSpCas9	negative selection	5348871
18923103	18923125	22	+	27760321	HT29	viability after 10 days	TCTAGCACTTACCAGAAACTGG	PRODH	ENSG00000100033	-0.4638462914964523	[191,149]	[182,93,184]	-5	hSpCas9	negative selection	5348872
18925149	18925171	22	+	27760321	MOLM13	viability	CGGTCCCCGAAGGCCCAGTGGG	PRODH	ENSG00000100033	0.11430918582125527	[576,514]	[628,80]	0	hSpCas9	negative selection	5432331
18925171	18925193	22	-	27760321	MOLM13	viability	AAGCGGGACAAGCAATACCAGG	PRODH	ENSG00000100033	0.7625136224440754	[382,278]	[437,207]	5	hSpCas9	negative selection	5432332
18922355	18922377	22	+	27760321	MOLM13	viability	CAGTCCTCAATCTCAGCCCTGG	PRODH	ENSG00000100033	-0.14471031407996826	[947,756]	[297,546]	-1	hSpCas9	negative selection	5432333
18922386	18922408	22	-	27760321	MOLM13	viability	AAGGAAAGTGTCGCAAAGTTGG	PRODH	ENSG00000100033	0.12910797216455183	[158,153]	[52,133]	0	hSpCas9	negative selection	5432334
18923103	18923125	22	+	27760321	MOLM13	viability	TCTAGCACTTACCAGAAACTGG	PRODH	ENSG00000100033	-0.005635304973142796	[171,191]	[101,103]	0	hSpCas9	negative selection	5432335
18918312	18918335	22	+	27661255	K562	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	-0.10045099662160517	[524,563]	[456,360]	-4	dCas9-KRAB	negative selection	5504319
18918327	18918350	22	+	27661255	K562	viability	GGCGTTGGTGGCCTCGTACGTGG	PRODH	ENSG00000100033	0.18202745129343298	[805,601]	[616,661]	6	dCas9-KRAB	negative selection	5504320
18935832	18935855	22	+	27661255	K562	viability	GTTGGTAGACATCGACAAATAGG	PRODH	ENSG00000100033	0.08339301272767763	[2170,2454]	[2152,1782]	3	dCas9-KRAB	negative selection	5504321
18936154	18936177	22	+	27661255	K562	viability	GCCGTGGCCGACCCACCTCCTGG	PRODH	ENSG00000100033	0.2913852970768388	[368,368]	[404,322]	8	dCas9-KRAB	negative selection	5504322
18936233	18936256	22	+	27661255	K562	viability	GGACGAAGCGGGGAATGCAGGGG	PRODH	ENSG00000100033	0.22448613186471417	[845,885]	[833,784]	7	dCas9-KRAB	negative selection	5504323
18936275	18936298	22	+	27661255	K562	viability	GCCTCAGAGCCATGGCGGGACGG	PRODH	ENSG00000100033	0.05221339101800848	[508,610]	[552,384]	1	dCas9-KRAB	negative selection	5504324
18918380	18918403	22	-	27661255	K562	viability	GGCCCAGGAGCGAGCCCGTGCGG	PRODH	ENSG00000100033	0.21135442798199033	[481,543]	[440,500]	7	dCas9-KRAB	negative selection	5504325
18935936	18935959	22	-	27661255	K562	viability	GGAGCTTCCTGGCCTGAAACGGG	PRODH	ENSG00000100033	0.16807769903444625	[973,1090]	[981,875]	6	dCas9-KRAB	negative selection	5504326
18918370	18918393	22	-	27260156	BXPC3	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.04924826351018584	[519]	[501,504,525,574]	-1	hSpCas9	negative selection	5564754
18918370	18918393	22	-	27260156	A673	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.15667891273222484	[519]	[560,496,542,644]	-4	hSpCas9	negative selection	5686005
18918370	18918393	22	-	27260156	A375	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.09887249240345886	[519]	[645,607,584,447]	-1	hSpCas9	negative selection	5807256
18918370	18918393	22	-	27260156	COLO741	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.2530158861872228	[519]	[764,823,782]	5	hSpCas9	negative selection	5928507
18918370	18918393	22	-	27260156	CAL120	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.24135313860407676	[519]	[792,815,690]	3	hSpCas9	negative selection	6049758
18918370	18918393	22	-	27260156	CADOES1	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.09146717897186074	[519]	[361,513,478,713]	1	hSpCas9	negative selection	6171009
18918370	18918393	22	-	27260156	EWS502	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.043830916558262115	[519]	[420,503,584,648]	-1	hSpCas9	negative selection	6292260
18918370	18918393	22	-	27260156	EW8	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.016356168930545284	[519]	[361,431,274,613]	0	hSpCas9	negative selection	6413511
18918370	18918393	22	-	27260156	CORL105	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.017253176434077228	[519]	[637,511,634,628]	0	hSpCas9	negative selection	6534762
18918370	18918393	22	-	27260156	HS294T	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.22622742226418824	[519]	[156,144,216,169]	-3	hSpCas9	negative selection	6656013
18918370	18918393	22	-	27260156	HCC44	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.2177043057386222	[519]	[877,656,490,691]	3	hSpCas9	negative selection	6777264
18918370	18918393	22	-	27260156	G402	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.17982288294918652	[519]	[892,617,397,969]	2	hSpCas9	negative selection	6898515
18918370	18918393	22	-	27260156	L33	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.027621100539564722	[519]	[534,209,348,437]	0	hSpCas9	negative selection	7019766
18918370	18918393	22	-	27260156	K562	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.23220377567565234	[519]	[297,418,534,319]	-3	hSpCas9	negative selection	7141017
18918370	18918393	22	-	27260156	HT29	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.19351805993055182	[519]	[740,467,584,434]	-4	hSpCas9	negative selection	7262268
18918370	18918393	22	-	27260156	MHHES1	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.518808645794817	[519]	[557,476,386,262]	-7	hSpCas9	negative selection	7383519
18918370	18918393	22	-	27260156	MEWO	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.16016264847570721	[519]	[691,433,533]	3	hSpCas9	negative selection	7504770
18918370	18918393	22	-	27260156	LNCAPCLONEFGC	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.060608848928303066	[519]	[506,448,543,474]	0	hSpCas9	negative selection	7626021
18918370	18918393	22	-	27260156	PANC0327	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.09916212115749154	[519]	[341,456,399,771]	1	hSpCas9	negative selection	7747272
18918370	18918393	22	-	27260156	NCIH2009	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.007923610864004754	[519]	[1020,633,571]	0	hSpCas9	negative selection	7868523
18918370	18918393	22	-	27260156	NCIH1373	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.04320866341731239	[519]	[834,421,589,159]	0	hSpCas9	negative selection	7989774
18918370	18918393	22	-	27260156	PATU8902	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.12414165391152293	[519]	[1021,581,420,1275]	1	hSpCas9	negative selection	8111025
18918370	18918393	22	-	27260156	PANC1	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.34857952984183194	[519]	[385,327,349,330]	-5	hSpCas9	negative selection	8232276
18918370	18918393	22	-	27260156	PANC0813	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.07090963560004027	[519]	[503,735,642,667]	1	hSpCas9	negative selection	8353527
18918370	18918393	22	-	27260156	RDES	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.14930233751133037	[519]	[700,596,684,641]	2	hSpCas9	negative selection	8474778
18918370	18918393	22	-	27260156	PC3	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.12670890550430317	[519]	[283,394,853,561]	-3	hSpCas9	negative selection	8596029
18918370	18918393	22	-	27260156	PATU8988T	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.13492000939278948	[519]	[428,836,401,568]	2	hSpCas9	negative selection	8717280
18918370	18918393	22	-	27260156	T47D	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.03789398277008135	[519]	[616,556,673,644]	0	hSpCas9	negative selection	8838531
18918370	18918393	22	-	27260156	SU8686	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.01915093458605832	[519]	[470,585,402,638]	0	hSpCas9	negative selection	8959782
18918370	18918393	22	-	27260156	SKES1	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.2032438958792021	[519]	[340,507,461,474]	-4	hSpCas9	negative selection	9081033
18918370	18918393	22	-	27260156	TOV112D	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.06530106615455039	[519]	[450,638,666,439]	1	hSpCas9	negative selection	9202284
18918370	18918393	22	-	27260156	TC71	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	-0.051133876340644396	[519]	[503,570,565,508]	-1	hSpCas9	negative selection	9323535
18918370	18918393	22	-	27260156	TC32	viability	CGAGCCCGTGCGGCAGAGATCGG	PRODH	ENSG00000100033	0.24936675332598907	[519]	[558,466,690,638]	4	hSpCas9	negative selection	9444786
18913161	18913184	22	+	27869803	HPAFII	viability after 27 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	-0.05460986282821545	[504]	[379,151,NaN]	0	hSpCas9	negative selection	9579745
18922904	18922927	22	-	27869803	HPAFII	viability after 27 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	-0.22652362163923567	[471]	[258,172,NaN]	-2	hSpCas9	negative selection	9579746
18923132	18923155	22	-	27869803	HPAFII	viability after 27 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	0.9892488542681258	[305]	[494,172,NaN]	7	hSpCas9	negative selection	9579747
18925186	18925209	22	-	27869803	HPAFII	viability after 27 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.5187749088083742	[195]	[157,138,NaN]	4	hSpCas9	negative selection	9579748
18925693	18925716	22	-	27869803	HPAFII	viability after 27 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-1.4407032762033984	[137]	[29,23,NaN]	-7	hSpCas9	negative selection	9579749
18931031	18931054	22	+	27869803	HPAFII	viability after 27 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	-0.6341012225095441	[284]	[53,131,NaN]	-4	hSpCas9	negative selection	9579750
18913161	18913184	22	+	27869803	HPAFII	viability after 15 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.32881873704904163	[504]	[730,650,NaN]	4	hSpCas9	negative selection	9662194
18922904	18922927	22	-	27869803	HPAFII	viability after 15 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.062249784553323195	[471]	[594,488,NaN]	0	hSpCas9	negative selection	9662195
18923132	18923155	22	-	27869803	HPAFII	viability after 15 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	0.6701722629383835	[305]	[674,428,NaN]	7	hSpCas9	negative selection	9662196
18925186	18925209	22	-	27869803	HPAFII	viability after 15 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.23614927461921367	[195]	[347,185,NaN]	2	hSpCas9	negative selection	9662197
18925693	18925716	22	-	27869803	HPAFII	viability after 15 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-0.5659686524714516	[137]	[122,85,NaN]	-6	hSpCas9	negative selection	9662198
18931031	18931054	22	+	27869803	HPAFII	viability after 15 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	-0.3789602244696444	[284]	[311,187,NaN]	-4	hSpCas9	negative selection	9662199
18913161	18913184	22	+	27869803	ASPC1	viability after 36 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.6990966138985968	[1058]	[715,1105,110]	7	hSpCas9	negative selection	9744643
18922904	18922927	22	-	27869803	ASPC1	viability after 36 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.535209517953134	[1152]	[440,1212,176]	5	hSpCas9	negative selection	9744644
18923132	18923155	22	-	27869803	ASPC1	viability after 36 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	1.1520787022961247	[832]	[765,492,676]	9	hSpCas9	negative selection	9744645
18925186	18925209	22	-	27869803	ASPC1	viability after 36 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	-0.32937810145893276	[398]	[106,99,120]	-3	hSpCas9	negative selection	9744646
18925693	18925716	22	-	27869803	ASPC1	viability after 36 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-1.1513937356717772	[246]	[33,64,20]	-8	hSpCas9	negative selection	9744647
18931031	18931054	22	+	27869803	ASPC1	viability after 36 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	0.40900962342834557	[652]	[649,183,149]	4	hSpCas9	negative selection	9744648
18913161	18913184	22	+	27869803	PATU8988S	viability after 35 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.6431425948661275	[864]	[356,731,NaN]	7	hSpCas9	negative selection	9827092
18922904	18922927	22	-	27869803	PATU8988S	viability after 35 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	-0.0732113231011211	[916]	[371,329,NaN]	0	hSpCas9	negative selection	9827093
18923132	18923155	22	-	27869803	PATU8988S	viability after 35 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	-0.18963213285024766	[669]	[282,189,NaN]	-2	hSpCas9	negative selection	9827094
18925186	18925209	22	-	27869803	PATU8988S	viability after 35 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	-0.3393952200676811	[315]	[139,60,NaN]	-4	hSpCas9	negative selection	9827095
18925693	18925716	22	-	27869803	PATU8988S	viability after 35 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	0.1471154868111637	[202]	[105,74,NaN]	1	hSpCas9	negative selection	9827096
18931031	18931054	22	+	27869803	PATU8988S	viability after 35 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	0.12829887767200882	[648]	[370,199,NaN]	1	hSpCas9	negative selection	9827097
18913161	18913184	22	+	27869803	PATU8988S	viability after 31 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.488868730871184	[864]	[249,781,NaN]	6	hSpCas9	negative selection	9909541
18922904	18922927	22	-	27869803	PATU8988S	viability after 31 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.22906586448562316	[916]	[461,385,NaN]	3	hSpCas9	negative selection	9909542
18923132	18923155	22	-	27869803	PATU8988S	viability after 31 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	-0.2783328169061494	[669]	[236,198,NaN]	-3	hSpCas9	negative selection	9909543
18925186	18925209	22	-	27869803	PATU8988S	viability after 31 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	-0.47965629851942304	[315]	[103,72,NaN]	-5	hSpCas9	negative selection	9909544
18925693	18925716	22	-	27869803	PATU8988S	viability after 31 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-0.4387001715708163	[202]	[64,52,NaN]	-5	hSpCas9	negative selection	9909545
18931031	18931054	22	+	27869803	PATU8988S	viability after 31 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	0.26518433148162135	[648]	[332,282,NaN]	3	hSpCas9	negative selection	9909546
18913161	18913184	22	+	27869803	HPAFII	viability after 35 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	0.30226083632700096	[504]	[445,167,NaN]	2	hSpCas9	negative selection	9991990
18922904	18922927	22	-	27869803	HPAFII	viability after 35 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.13925317896814926	[471]	[233,295,NaN]	0	hSpCas9	negative selection	9991991
18923132	18923155	22	-	27869803	HPAFII	viability after 35 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	1.160910226477625	[305]	[399,285,NaN]	7	hSpCas9	negative selection	9991992
18925186	18925209	22	-	27869803	HPAFII	viability after 35 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.5001197205302901	[195]	[105,178,NaN]	3	hSpCas9	negative selection	9991993
18925693	18925716	22	-	27869803	HPAFII	viability after 35 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-0.9245541355675202	[137]	[1,75,NaN]	-5	hSpCas9	negative selection	9991994
18931031	18931054	22	+	27869803	HPAFII	viability after 35 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	-0.7002032557021681	[284]	[45,136,NaN]	-4	hSpCas9	negative selection	9991995
18913161	18913184	22	+	27869803	HPAFII	viability after 31 days	TGTGCTGGCGGGTGCTAGGCAGG	PRODH	ENSG00000100033	-0.04067285856340608	[504]	[387,152,NaN]	0	hSpCas9	negative selection	10074439
18922904	18922927	22	-	27869803	HPAFII	viability after 31 days	TCTCAGAGGTGCTGGCCAAGTGG	PRODH	ENSG00000100033	0.2636111055977717	[471]	[183,463,NaN]	1	hSpCas9	negative selection	10074440
18923132	18923155	22	-	27869803	HPAFII	viability after 31 days	AGCCATTAAGCTCACAGCACTGG	PRODH	ENSG00000100033	0.7811133063287113	[305]	[386,194,NaN]	6	hSpCas9	negative selection	10074441
18925186	18925209	22	-	27869803	HPAFII	viability after 31 days	TATTCCAGGCACGAATAAGCGGG	PRODH	ENSG00000100033	0.3452920879528727	[195]	[133,145,NaN]	2	hSpCas9	negative selection	10074442
18925693	18925716	22	-	27869803	HPAFII	viability after 31 days	ACCTCAGCTGCGGAGAGGGATGG	PRODH	ENSG00000100033	-1.4608225724338348	[137]	[19,36,NaN]	-7	hSpCas9	negative selection	10074443
18931031	18931054	22	+	27869803	HPAFII	viability after 31 days	CTCCACTCCATAGTCCAGGATGG	PRODH	ENSG00000100033	-0.34777004041168874	[284]	[140,108,NaN]	-2	hSpCas9	negative selection	10074444
18931009	18931032	22	-	28162770	P31FUJ	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-2.804344189373213	[213]	[35]	-9	hSpCas9	negative selection	10217439
18931046	18931069	22	+	28162770	P31FUJ	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	0.9296282604810093	[192]	[431]	9	hSpCas9	negative selection	10217440
18913474	18913497	22	+	28162770	P31FUJ	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.550879888658858	[157]	[271]	6	hSpCas9	negative selection	10217441
18931068	18931091	22	+	28162770	P31FUJ	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-0.6834636134239438	[81]	[59]	-5	hSpCas9	negative selection	10217442
18930991	18931014	22	-	28162770	P31FUJ	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-2.132275328460414	[96]	[25]	-8	hSpCas9	negative selection	10217443
18925703	18925726	22	-	28162770	P31FUJ	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.690274970013619	[459]	[334]	-5	hSpCas9	negative selection	10217444
18925687	18925710	22	-	28162770	P31FUJ	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-0.9721504498915787	[201]	[120]	-6	hSpCas9	negative selection	10217445
18919753	18919776	22	-	28162770	P31FUJ	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	-0.15584022259949443	[218]	[230]	-1	hSpCas9	negative selection	10217446
18919507	18919530	22	+	28162770	P31FUJ	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	-0.18492557746359772	[325]	[336]	-2	hSpCas9	negative selection	10217447
18918312	18918335	22	+	28162770	P31FUJ	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	-0.21997816405679504	[335]	[338]	-2	hSpCas9	negative selection	10217448
18931009	18931032	22	-	28162770	TF1	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10386805
18931046	18931069	22	+	28162770	TF1	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10386806
18913474	18913497	22	+	28162770	TF1	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	NaN	[NaN]	[249]	1	hSpCas9	negative selection	10386807
18931068	18931091	22	+	28162770	TF1	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10386808
18930991	18931014	22	-	28162770	TF1	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10386809
18925703	18925726	22	-	28162770	TF1	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	NaN	[NaN]	[275]	1	hSpCas9	negative selection	10386810
18925687	18925710	22	-	28162770	TF1	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10386811
18919753	18919776	22	-	28162770	TF1	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	NaN	[NaN]	[66]	1	hSpCas9	negative selection	10386812
18919507	18919530	22	+	28162770	TF1	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	NaN	[NaN]	[394]	1	hSpCas9	negative selection	10386813
18918312	18918335	22	+	28162770	TF1	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	NaN	[NaN]	[230]	1	hSpCas9	negative selection	10386814
18931009	18931032	22	-	28162770	SKM1	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-2.7939873218524087	[50]	[12]	-9	hSpCas9	negative selection	10556171
18931046	18931069	22	+	28162770	SKM1	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	0.5447806326496173	[56]	[146]	5	hSpCas9	negative selection	10556172
18913474	18913497	22	+	28162770	SKM1	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	-0.16080361147376415	[42]	[67]	-1	hSpCas9	negative selection	10556173
18931068	18931091	22	+	28162770	SKM1	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-2.0630097975258006	[25]	[10]	-8	hSpCas9	negative selection	10556174
18930991	18931014	22	-	28162770	SKM1	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-1.3074285251922473	[34]	[24]	-7	hSpCas9	negative selection	10556175
18925703	18925726	22	-	28162770	SKM1	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.996499429254142	[157]	[139]	-6	hSpCas9	negative selection	10556176
18925687	18925710	22	-	28162770	SKM1	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-2.484966710744435	[37]	[11]	-9	hSpCas9	negative selection	10556177
18919753	18919776	22	-	28162770	SKM1	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	-0.3182352801488301	[66]	[94]	-3	hSpCas9	negative selection	10556178
18919507	18919530	22	+	28162770	SKM1	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	0.5860830406150714	[51]	[137]	5	hSpCas9	negative selection	10556179
18918312	18918335	22	+	28162770	SKM1	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	0.04620842942245315	[62]	[114]	0	hSpCas9	negative selection	10556180
18931009	18931032	22	-	28162770	SKM1	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-2.7939873218524087	[50]	[12]	-9	hSpCas9	negative selection	10725537
18931046	18931069	22	+	28162770	SKM1	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	0.5447806326496173	[56]	[146]	5	hSpCas9	negative selection	10725538
18913474	18913497	22	+	28162770	SKM1	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	-0.16080361147376415	[42]	[67]	-1	hSpCas9	negative selection	10725539
18931068	18931091	22	+	28162770	SKM1	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-2.0630097975258006	[25]	[10]	-8	hSpCas9	negative selection	10725540
18930991	18931014	22	-	28162770	SKM1	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-1.3074285251922473	[34]	[24]	-7	hSpCas9	negative selection	10725541
18925703	18925726	22	-	28162770	SKM1	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.996499429254142	[157]	[139]	-6	hSpCas9	negative selection	10725542
18925687	18925710	22	-	28162770	SKM1	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-2.484966710744435	[37]	[11]	-9	hSpCas9	negative selection	10725543
18919753	18919776	22	-	28162770	SKM1	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	-0.3182352801488301	[66]	[94]	-3	hSpCas9	negative selection	10725544
18919507	18919530	22	+	28162770	SKM1	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	0.5860830406150714	[51]	[137]	5	hSpCas9	negative selection	10725545
18918312	18918335	22	+	28162770	SKM1	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	0.04620842942245315	[62]	[114]	0	hSpCas9	negative selection	10725546
18931009	18931032	22	-	28162770	PL21	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-0.5281870614030134	[221]	[66]	-4	hSpCas9	negative selection	10894903
18931046	18931069	22	+	28162770	PL21	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	-0.49646824206074514	[187]	[57]	-4	hSpCas9	negative selection	10894904
18913474	18913497	22	+	28162770	PL21	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.29529684752966023	[175]	[93]	2	hSpCas9	negative selection	10894905
18931068	18931091	22	+	28162770	PL21	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-0.6873856562522673	[73]	[19]	-5	hSpCas9	negative selection	10894906
18930991	18931014	22	-	28162770	PL21	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	0.5136390873061016	[102]	[63]	4	hSpCas9	negative selection	10894907
18925703	18925726	22	-	28162770	PL21	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.007018293151967558	[470]	[203]	0	hSpCas9	negative selection	10894908
18925687	18925710	22	-	28162770	PL21	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-0.6914842244658881	[140]	[37]	-5	hSpCas9	negative selection	10894909
18919753	18919776	22	-	28162770	PL21	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	1.0918867238372967	[165]	[153]	8	hSpCas9	negative selection	10894910
18919507	18919530	22	+	28162770	PL21	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	0.18005536844598768	[216]	[106]	1	hSpCas9	negative selection	10894911
18918312	18918335	22	+	28162770	PL21	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	1.695834777113389	[199]	[281]	9	hSpCas9	negative selection	10894912
18931009	18931032	22	-	28162770	P31FUJ	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-2.804344189373213	[213]	[35]	-9	hSpCas9	negative selection	11064269
18931046	18931069	22	+	28162770	P31FUJ	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	0.9296282604810093	[192]	[431]	9	hSpCas9	negative selection	11064270
18913474	18913497	22	+	28162770	P31FUJ	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.550879888658858	[157]	[271]	6	hSpCas9	negative selection	11064271
18931068	18931091	22	+	28162770	P31FUJ	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-0.6834636134239438	[81]	[59]	-5	hSpCas9	negative selection	11064272
18930991	18931014	22	-	28162770	P31FUJ	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-2.132275328460414	[96]	[25]	-8	hSpCas9	negative selection	11064273
18925703	18925726	22	-	28162770	P31FUJ	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.690274970013619	[459]	[334]	-5	hSpCas9	negative selection	11064274
18925687	18925710	22	-	28162770	P31FUJ	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-0.9721504498915787	[201]	[120]	-6	hSpCas9	negative selection	11064275
18919753	18919776	22	-	28162770	P31FUJ	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	-0.15584022259949443	[218]	[230]	-1	hSpCas9	negative selection	11064276
18919507	18919530	22	+	28162770	P31FUJ	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	-0.18492557746359772	[325]	[336]	-2	hSpCas9	negative selection	11064277
18918312	18918335	22	+	28162770	P31FUJ	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	-0.21997816405679504	[335]	[338]	-2	hSpCas9	negative selection	11064278
18931009	18931032	22	-	28162770	OCIAML5	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-2.033673377353945	[92]	[40]	-8	hSpCas9	negative selection	11233635
18931046	18931069	22	+	28162770	OCIAML5	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	0.4308673924075017	[89]	[218]	3	hSpCas9	negative selection	11233636
18913474	18913497	22	+	28162770	OCIAML5	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.6223752156124422	[112]	[313]	5	hSpCas9	negative selection	11233637
18931068	18931091	22	+	28162770	OCIAML5	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-6.278331325566095	[42]	[0]	-9	hSpCas9	negative selection	11233638
18930991	18931014	22	-	28162770	OCIAML5	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-0.47146256864902725	[52]	[68]	-3	hSpCas9	negative selection	11233639
18925703	18925726	22	-	28162770	OCIAML5	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.9945108358842024	[350]	[317]	-6	hSpCas9	negative selection	11233640
18925687	18925710	22	-	28162770	OCIAML5	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-2.5150315835864268	[132]	[41]	-8	hSpCas9	negative selection	11233641
18919753	18919776	22	-	28162770	OCIAML5	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	0.16695825481775922	[112]	[228]	1	hSpCas9	negative selection	11233642
18919507	18919530	22	+	28162770	OCIAML5	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	0.6962773386210052	[132]	[388]	6	hSpCas9	negative selection	11233643
18918312	18918335	22	+	28162770	OCIAML5	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	0.06940002658931371	[150]	[285]	0	hSpCas9	negative selection	11233644
18931009	18931032	22	-	28162770	EOL1	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-3.8033726829926646	[370]	[13]	-9	hSpCas9	negative selection	11403001
18931046	18931069	22	+	28162770	EOL1	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	1.572387475263757	[216]	[339]	9	hSpCas9	negative selection	11403002
18913474	18913497	22	+	28162770	EOL1	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.20491205594224554	[330]	[200]	1	hSpCas9	negative selection	11403003
18931068	18931091	22	+	28162770	EOL1	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-0.19092944584940152	[103]	[47]	-1	hSpCas9	negative selection	11403004
18930991	18931014	22	-	28162770	EOL1	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-1.982342824037984	[209]	[27]	-8	hSpCas9	negative selection	11403005
18925703	18925726	22	-	28162770	EOL1	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.34821023803949114	[922]	[381]	-3	hSpCas9	negative selection	11403006
18925687	18925710	22	-	28162770	EOL1	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-1.5313347799856918	[202]	[36]	-7	hSpCas9	negative selection	11403007
18919753	18919776	22	-	28162770	EOL1	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	0.1286884883507599	[249]	[143]	1	hSpCas9	negative selection	11403008
18919507	18919530	22	+	28162770	EOL1	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	0.16711807484461283	[283]	[167]	1	hSpCas9	negative selection	11403009
18918312	18918335	22	+	28162770	EOL1	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	-0.5229112054006868	[269]	[98]	-4	hSpCas9	negative selection	11403010
18931009	18931032	22	-	28162770	MOLM13	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-6.029297159088136	[270]	[2]	-9	hSpCas9	negative selection	11572367
18931046	18931069	22	+	28162770	MOLM13	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	-0.9831463159716619	[256]	[93]	-5	hSpCas9	negative selection	11572368
18913474	18913497	22	+	28162770	MOLM13	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	1.184610470436613	[243]	[400]	8	hSpCas9	negative selection	11572369
18931068	18931091	22	+	28162770	MOLM13	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-1.0346109589846046	[84]	[29]	-5	hSpCas9	negative selection	11572370
18930991	18931014	22	-	28162770	MOLM13	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-2.0810038644690554	[157]	[26]	-7	hSpCas9	negative selection	11572371
18925703	18925726	22	-	28162770	MOLM13	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.5215927465414218	[819]	[412]	-3	hSpCas9	negative selection	11572372
18925687	18925710	22	-	28162770	MOLM13	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-2.5321106184554214	[191]	[23]	-8	hSpCas9	negative selection	11572373
18919753	18919776	22	-	28162770	MOLM13	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	-0.2419825517393524	[210]	[128]	-1	hSpCas9	negative selection	11572374
18919507	18919530	22	+	28162770	MOLM13	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	0.4205836667662223	[309]	[299]	3	hSpCas9	negative selection	11572375
18918312	18918335	22	+	28162770	MOLM13	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	-0.07807898756071356	[291]	[199]	0	hSpCas9	negative selection	11572376
18931009	18931032	22	-	28162770	HEL	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-5.777923216472365	[256]	[2]	-9	hSpCas9	negative selection	11741733
18931046	18931069	22	+	28162770	HEL	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	0.03305390186796939	[205]	[134]	0	hSpCas9	negative selection	11741734
18913474	18913497	22	+	28162770	HEL	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.941928002592681	[242]	[298]	7	hSpCas9	negative selection	11741735
18931068	18931091	22	+	28162770	HEL	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-0.8654080716699682	[127]	[44]	-5	hSpCas9	negative selection	11741736
18930991	18931014	22	-	28162770	HEL	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-1.0491388726373114	[125]	[38]	-6	hSpCas9	negative selection	11741737
18925703	18925726	22	-	28162770	HEL	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.6283197449182586	[612]	[253]	-4	hSpCas9	negative selection	11741738
18925687	18925710	22	-	28162770	HEL	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-2.1142844145071025	[168]	[24]	-8	hSpCas9	negative selection	11741739
18919753	18919776	22	-	28162770	HEL	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	0.09282327837840137	[182]	[124]	0	hSpCas9	negative selection	11741740
18919507	18919530	22	+	28162770	HEL	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	0.39958785049711154	[244]	[206]	3	hSpCas9	negative selection	11741741
18918312	18918335	22	+	28162770	HEL	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	0.569422154357436	[221]	[210]	5	hSpCas9	negative selection	11741742
18931009	18931032	22	-	28162770	MV411	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-3.4155274619396536	[227]	[17]	-9	hSpCas9	negative selection	11911099
18931046	18931069	22	+	28162770	MV411	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	0.995898783786811	[149]	[251]	8	hSpCas9	negative selection	11911100
18913474	18913497	22	+	28162770	MV411	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.6752342807769606	[196]	[264]	6	hSpCas9	negative selection	11911101
18931068	18931091	22	+	28162770	MV411	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-0.5155232519163755	[55]	[32]	-4	hSpCas9	negative selection	11911102
18930991	18931014	22	-	28162770	MV411	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-0.4530021673583169	[90]	[55]	-3	hSpCas9	negative selection	11911103
18925703	18925726	22	-	28162770	MV411	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-1.4289212786792789	[504]	[157]	-7	hSpCas9	negative selection	11911104
18925687	18925710	22	-	28162770	MV411	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-1.544757564103823	[141]	[40]	-7	hSpCas9	negative selection	11911105
18919753	18919776	22	-	28162770	MV411	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	-1.8877220324988602	[122]	[27]	-8	hSpCas9	negative selection	11911106
18919507	18919530	22	+	28162770	MV411	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	-0.4395595841093462	[226]	[140]	-3	hSpCas9	negative selection	11911107
18918312	18918335	22	+	28162770	MV411	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	-0.9179860584245962	[239]	[106]	-6	hSpCas9	negative selection	11911108
18931009	18931032	22	-	28162770	MONOMAC1	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-1.9308627336951925	[152]	[45]	-8	hSpCas9	negative selection	12080465
18931046	18931069	22	+	28162770	MONOMAC1	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	0.8029631529404463	[74]	[149]	7	hSpCas9	negative selection	12080466
18913474	18913497	22	+	28162770	MONOMAC1	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.9043651851486594	[102]	[220]	8	hSpCas9	negative selection	12080467
18931068	18931091	22	+	28162770	MONOMAC1	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	0.27503159725566917	[30]	[42]	2	hSpCas9	negative selection	12080468
18930991	18931014	22	-	28162770	MONOMAC1	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-0.9269476836918095	[67]	[40]	-6	hSpCas9	negative selection	12080469
18925703	18925726	22	-	28162770	MONOMAC1	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.8369477571786004	[387]	[248]	-6	hSpCas9	negative selection	12080470
18925687	18925710	22	-	28162770	MONOMAC1	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-0.1548086116702564	[100]	[103]	-1	hSpCas9	negative selection	12080471
18919753	18919776	22	-	28162770	MONOMAC1	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	1.1676595334335425	[112]	[290]	8	hSpCas9	negative selection	12080472
18919507	18919530	22	+	28162770	MONOMAC1	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	-0.12615336090304402	[138]	[145]	-1	hSpCas9	negative selection	12080473
18918312	18918335	22	+	28162770	MONOMAC1	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	0.7860893343760501	[128]	[254]	7	hSpCas9	negative selection	12080474
18931009	18931032	22	-	28162770	OCIAML2	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-0.7172697928252866	[34]	[117]	-5	hSpCas9	negative selection	12249831
18931046	18931069	22	+	28162770	OCIAML2	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	-0.1219016710110836	[31]	[162]	-1	hSpCas9	negative selection	12249832
18913474	18913497	22	+	28162770	OCIAML2	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.3622601889225806	[39]	[284]	3	hSpCas9	negative selection	12249833
18931068	18931091	22	+	28162770	OCIAML2	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	-0.21189555684199313	[13]	[66]	-2	hSpCas9	negative selection	12249834
18930991	18931014	22	-	28162770	OCIAML2	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-1.1487017303547988	[23]	[59]	-6	hSpCas9	negative selection	12249835
18925703	18925726	22	-	28162770	OCIAML2	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	-0.3153515997642504	[98]	[440]	-3	hSpCas9	negative selection	12249836
18925687	18925710	22	-	28162770	OCIAML2	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-4.52125589831213	[28]	[6]	-9	hSpCas9	negative selection	12249837
18919753	18919776	22	-	28162770	OCIAML2	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	0.15230052567801533	[24]	[153]	1	hSpCas9	negative selection	12249838
18919507	18919530	22	+	28162770	OCIAML2	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	0.43365897517807733	[36]	[276]	4	hSpCas9	negative selection	12249839
18918312	18918335	22	+	28162770	OCIAML2	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	-0.49543321624273373	[43]	[172]	-4	hSpCas9	negative selection	12249840
18931009	18931032	22	-	28162770	OCIAML3	viability	GGAGGACCTGAGCCCCGAGGAGG	PRODH	ENSG00000100033	-1.8769416035956619	[72]	[59]	-8	hSpCas9	negative selection	12419197
18931046	18931069	22	+	28162770	OCIAML3	viability	CAGGATGGCGCTGACACCGAAGG	PRODH	ENSG00000100033	0.18560229125053682	[59]	[205]	1	hSpCas9	negative selection	12419198
18913474	18913497	22	+	28162770	OCIAML3	viability	GCTGTCCAAAGTACACCCGGTGG	PRODH	ENSG00000100033	0.9181042949893115	[43]	[250]	7	hSpCas9	negative selection	12419199
18931068	18931091	22	+	28162770	OCIAML3	viability	GCCCTGTAGTGCCGAAGCAGGGG	PRODH	ENSG00000100033	1.1785818635727643	[11]	[81]	8	hSpCas9	negative selection	12419200
18930991	18931014	22	-	28162770	OCIAML3	viability	GGAGGCAGAGCACAAGGAGATGG	PRODH	ENSG00000100033	-1.009045139603007	[29]	[44]	-6	hSpCas9	negative selection	12419201
18925703	18925726	22	-	28162770	OCIAML3	viability	CAGGTCCTGCACCTCAGCTGCGG	PRODH	ENSG00000100033	0.18771135474659184	[145]	[501]	1	hSpCas9	negative selection	12419202
18925687	18925710	22	-	28162770	OCIAML3	viability	GCTGCGGAGAGGGATGGCAGTGG	PRODH	ENSG00000100033	-2.297025902567032	[69]	[42]	-9	hSpCas9	negative selection	12419203
18919753	18919776	22	-	28162770	OCIAML3	viability	GTCCCGGTTCACTGAGGAGGAGG	PRODH	ENSG00000100033	0.5651909545250907	[44]	[200]	5	hSpCas9	negative selection	12419204
18919507	18919530	22	+	28162770	OCIAML3	viability	GCTGCATCTCCAGCGTCAGGCGG	PRODH	ENSG00000100033	0.3399031692180645	[66]	[255]	3	hSpCas9	negative selection	12419205
18918312	18918335	22	+	28162770	OCIAML3	viability	GCACCTGTGGTACATGGCGTTGG	PRODH	ENSG00000100033	0.319736626325418	[55]	[210]	3	hSpCas9	negative selection	12419206