Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5693
• Symbol: PSMB5
• Description: proteasome 20S subunit beta 5

DataSource: http://genomecrispr.dkfz.de/#!/results/PSMB5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
23033416	23033439	14	-	26472758	Jiyoye	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-1.6166713604484944	[182]	[44]	-8	hSpCas9	negative selection	129715
23034769	23034792	14	-	26472758	Jiyoye	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-1.6004781910375616	[188]	[46]	-8	hSpCas9	negative selection	129716
23033388	23033411	14	-	26472758	Jiyoye	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-1.442490345409695	[172]	[47]	-7	hSpCas9	negative selection	129717
23033438	23033461	14	+	26472758	Jiyoye	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	-2.2383286611503337	[218]	[34]	-8	hSpCas9	negative selection	129718
23033373	23033396	14	-	26472758	Jiyoye	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-0.9379601045428142	[93]	[36]	-6	hSpCas9	negative selection	129719
23033404	23033427	14	-	26472758	Jiyoye	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	-1.1631403432508813	[97]	[32]	-7	hSpCas9	negative selection	129720
23026352	23026375	14	+	26472758	Jiyoye	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.6742129453347816	[473]	[111]	-8	hSpCas9	negative selection	129721
23026361	23026384	14	-	26472758	Jiyoye	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-2.416191858540362	[452]	[63]	-8	hSpCas9	negative selection	129722
23033416	23033439	14	-	26472758	KBM7	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-1.0653701588590874	[914,846]	[242,157]	-7	hSpCas9	negative selection	320833
23034769	23034792	14	-	26472758	KBM7	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-0.9574609173242365	[799,615]	[141,194]	-6	hSpCas9	negative selection	320834
23033388	23033411	14	-	26472758	KBM7	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-0.8698819457639586	[792,636]	[280,94]	-6	hSpCas9	negative selection	320835
23033438	23033461	14	+	26472758	KBM7	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	-2.0991639913848967	[1155,811]	[123,90]	-8	hSpCas9	negative selection	320836
23033373	23033396	14	-	26472758	KBM7	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-1.0003945147078892	[1081,505]	[140,215]	-6	hSpCas9	negative selection	320837
23033404	23033427	14	-	26472758	KBM7	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	-1.0284446370959466	[413,415]	[149,47]	-7	hSpCas9	negative selection	320838
23026352	23026375	14	+	26472758	KBM7	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.4500648190715615	[1640,1990]	[380,259]	-7	hSpCas9	negative selection	320839
23026361	23026384	14	-	26472758	KBM7	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.5568788457967178	[1848,1478]	[539,517]	-5	hSpCas9	negative selection	320840
23033416	23033439	14	-	26472758	Raji	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-0.8122743563087971	[226]	[29]	-6	hSpCas9	negative selection	511951
23034769	23034792	14	-	26472758	Raji	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-1.9315354539187028	[525]	[31]	-8	hSpCas9	negative selection	511952
23033388	23033411	14	-	26472758	Raji	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-0.7278055948807303	[313]	[43]	-5	hSpCas9	negative selection	511953
23033438	23033461	14	+	26472758	Raji	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	-1.3261565501316739	[496]	[45]	-7	hSpCas9	negative selection	511954
23033373	23033396	14	-	26472758	Raji	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-0.11316753913868116	[260]	[55]	-1	hSpCas9	negative selection	511955
23033404	23033427	14	-	26472758	Raji	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	0.37946308081040014	[158]	[47]	3	hSpCas9	negative selection	511956
23026352	23026375	14	+	26472758	Raji	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.8122181119844731	[854]	[112]	-6	hSpCas9	negative selection	511957
23026361	23026384	14	-	26472758	Raji	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.6947442250204552	[1101]	[157]	-5	hSpCas9	negative selection	511958
23033416	23033439	14	-	26472758	K562	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-2.653497064250196	[640]	[85]	-8	hSpCas9	negative selection	703069
23034769	23034792	14	-	26472758	K562	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-1.1541306488238279	[550]	[208]	-6	hSpCas9	negative selection	703070
23033388	23033411	14	-	26472758	K562	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-1.9314311077329709	[609]	[134]	-7	hSpCas9	negative selection	703071
23033438	23033461	14	+	26472758	K562	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	-1.6531076510837603	[882]	[236]	-7	hSpCas9	negative selection	703072
23033373	23033396	14	-	26472758	K562	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-4.6173839784135335	[755]	[25]	-9	hSpCas9	negative selection	703073
23033404	23033427	14	-	26472758	K562	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	-3.371570668675334	[281]	[22]	-8	hSpCas9	negative selection	703074
23026352	23026375	14	+	26472758	K562	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-3.9069623804096723	[1545]	[86]	-9	hSpCas9	negative selection	703075
23026361	23026384	14	-	26472758	K562	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-2.8315842066884778	[1441]	[170]	-8	hSpCas9	negative selection	703076
23026357	23026380	14	+	26627737	DLD1	viability	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-3.089480820727685	[666]	[43,23,7]	-9	hSpCas9	negative selection	788076
23027749	23027772	14	-	26627737	DLD1	viability	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.3774513579087837	[1533]	[639,901,376]	4	hSpCas9	negative selection	788077
23033349	23033372	14	+	26627737	DLD1	viability	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-3.739217743880368	[344]	[22,0,0]	-9	hSpCas9	negative selection	788078
23034641	23034664	14	+	26627737	DLD1	viability	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	0.7880270758250176	[574]	[402,272,260]	7	hSpCas9	negative selection	788079
23034648	23034671	14	+	26627737	DLD1	viability	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.32379908093995513	[1527]	[408,401,340]	-3	hSpCas9	negative selection	788080
23026357	23026380	14	+	26627737	GBM cells	viability after 5 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-0.13361202863576185	[313]	[162,143]	-2	hSpCas9	negative selection	870391
23027749	23027772	14	-	26627737	GBM cells	viability after 5 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.015339298084670272	[701]	[397,362]	0	hSpCas9	negative selection	870392
23033349	23033372	14	+	26627737	GBM cells	viability after 5 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-0.6894076379253851	[214]	[57,84]	-8	hSpCas9	negative selection	870393
23034641	23034664	14	+	26627737	GBM cells	viability after 5 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	0.14478772956129649	[295]	[219,130]	2	hSpCas9	negative selection	870394
23034648	23034671	14	+	26627737	GBM cells	viability after 5 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.4581974295353808	[715]	[280,277]	-6	hSpCas9	negative selection	870395
23026357	23026380	14	+	26627737	GBM cells	viability after 13 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-0.12902067326613345	[313]	[157,153]	-1	hSpCas9	negative selection	952706
23027749	23027772	14	-	26627737	GBM cells	viability after 13 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.042973354777228634	[701]	[371,408]	0	hSpCas9	negative selection	952707
23033349	23033372	14	+	26627737	GBM cells	viability after 13 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-1.4699886791362586	[214]	[56,29]	-9	hSpCas9	negative selection	952708
23034641	23034664	14	+	26627737	GBM cells	viability after 13 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	0.25412728592196965	[295]	[233,156]	3	hSpCas9	negative selection	952709
23034648	23034671	14	+	26627737	GBM cells	viability after 13 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.47732521456721244	[715]	[390,187]	-5	hSpCas9	negative selection	952710
23026357	23026380	14	+	26627737	GBM cells	viability after 21 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-0.35717788703521314	[313]	[128,136]	-3	hSpCas9	negative selection	1035021
23027749	23027772	14	-	26627737	GBM cells	viability after 21 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.0974885690460392	[701]	[453,365]	1	hSpCas9	negative selection	1035022
23033349	23033372	14	+	26627737	GBM cells	viability after 21 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-2.6040904926611947	[214]	[25,12]	-9	hSpCas9	negative selection	1035023
23034641	23034664	14	+	26627737	GBM cells	viability after 21 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	-0.3846218700559917	[295]	[118,126]	-3	hSpCas9	negative selection	1035024
23034648	23034671	14	+	26627737	GBM cells	viability after 21 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.32049412462459603	[715]	[334,289]	-3	hSpCas9	negative selection	1035025
23026357	23026380	14	+	26627737	RPE1	viability after 9 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-3.7228769423299655	[1250]	[16,45]	-9	hSpCas9	negative selection	1117336
23027749	23027772	14	-	26627737	RPE1	viability after 9 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.12540678351399492	[3329]	[1110,1170]	0	hSpCas9	negative selection	1117337
23033349	23033372	14	+	26627737	RPE1	viability after 9 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-1.3171605623911695	[402]	[23,84]	-7	hSpCas9	negative selection	1117338
23034641	23034664	14	+	26627737	RPE1	viability after 9 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	-1.304737210770095	[1329]	[99,256]	-7	hSpCas9	negative selection	1117339
23034648	23034671	14	+	26627737	RPE1	viability after 9 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-1.1654168421272233	[2221]	[348,259]	-7	hSpCas9	negative selection	1117340
23026357	23026380	14	+	26627737	RPE1	viability after 12 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-5.842557579932202	[1250]	[0,10]	-9	hSpCas9	negative selection	1199651
23027749	23027772	14	-	26627737	RPE1	viability after 12 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.02986280056196522	[3329]	[959,863]	0	hSpCas9	negative selection	1199652
23033349	23033372	14	+	26627737	RPE1	viability after 12 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-2.827111702112242	[402]	[6,23]	-9	hSpCas9	negative selection	1199653
23034641	23034664	14	+	26627737	RPE1	viability after 12 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	-0.911894497102689	[1329]	[220,156]	-6	hSpCas9	negative selection	1199654
23034648	23034671	14	+	26627737	RPE1	viability after 12 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-1.006935020811045	[2221]	[366,222]	-6	hSpCas9	negative selection	1199655
23026357	23026380	14	+	26627737	RPE1	viability after 15 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-5.05136587415576	[1250]	[0,19]	-9	hSpCas9	negative selection	1281966
23027749	23027772	14	-	26627737	RPE1	viability after 15 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.384744360695052	[3329]	[1320,1141]	2	hSpCas9	negative selection	1281967
23033349	23033372	14	+	26627737	RPE1	viability after 15 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-1.0392948787121392	[402]	[0,107]	-6	hSpCas9	negative selection	1281968
23034641	23034664	14	+	26627737	RPE1	viability after 15 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	-0.8107191230511206	[1329]	[158,267]	-5	hSpCas9	negative selection	1281969
23034648	23034671	14	+	26627737	RPE1	viability after 15 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-1.0396802012794406	[2221]	[375,237]	-6	hSpCas9	negative selection	1281970
23026357	23026380	14	+	26627737	RPE1	viability after 18 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-6.830278155839644	[1250]	[1,3]	-9	hSpCas9	negative selection	1364281
23027749	23027772	14	-	26627737	RPE1	viability after 18 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.0382967479422196	[3329]	[990,849]	0	hSpCas9	negative selection	1364282
23033349	23033372	14	+	26627737	RPE1	viability after 18 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-2.938690393636309	[402]	[4,23]	-9	hSpCas9	negative selection	1364283
23034641	23034664	14	+	26627737	RPE1	viability after 18 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	-0.5428891836071356	[1329]	[256,234]	-3	hSpCas9	negative selection	1364284
23034648	23034671	14	+	26627737	RPE1	viability after 18 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-1.3876667404090064	[2221]	[175,285]	-7	hSpCas9	negative selection	1364285
23026357	23026380	14	+	26627737	HeLa	viability after 8 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	0.7062292481282834	[569]	[262,517,401]	6	hSpCas9	negative selection	1446596
23027749	23027772	14	-	26627737	HeLa	viability after 8 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.14484031704039402	[1286]	[793,601,507]	1	hSpCas9	negative selection	1446597
23033349	23033372	14	+	26627737	HeLa	viability after 8 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	0.30982195307736404	[146]	[26,99,97]	3	hSpCas9	negative selection	1446598
23034641	23034664	14	+	26627737	HeLa	viability after 8 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	0.07306339063094974	[508]	[415,56,263]	0	hSpCas9	negative selection	1446599
23034648	23034671	14	+	26627737	HeLa	viability after 8 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.25827372283317973	[1160]	[514,445,332]	-2	hSpCas9	negative selection	1446600
23026357	23026380	14	+	26627737	HeLa	viability after 12 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	0.020752495972710783	[569]	[307,209,203]	0	hSpCas9	negative selection	1528911
23027749	23027772	14	-	26627737	HeLa	viability after 12 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.16584293852666487	[1286]	[719,554,522]	1	hSpCas9	negative selection	1528912
23033349	23033372	14	+	26627737	HeLa	viability after 12 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	0.15412355699913727	[146]	[111,58,33]	1	hSpCas9	negative selection	1528913
23034641	23034664	14	+	26627737	HeLa	viability after 12 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	0.6865188811663046	[508]	[404,305,309]	5	hSpCas9	negative selection	1528914
23034648	23034671	14	+	26627737	HeLa	viability after 12 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.23020040115678886	[1160]	[485,317,434]	-2	hSpCas9	negative selection	1528915
23026357	23026380	14	+	26627737	HeLa	viability after 15 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-0.49097095725952217	[569]	[250,92,148]	-4	hSpCas9	negative selection	1611226
23027749	23027772	14	-	26627737	HeLa	viability after 15 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.3559178200930073	[1286]	[808,479,724]	3	hSpCas9	negative selection	1611227
23033349	23033372	14	+	26627737	HeLa	viability after 15 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-1.5434082610595523	[146]	[9,39,10]	-8	hSpCas9	negative selection	1611228
23034641	23034664	14	+	26627737	HeLa	viability after 15 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	0.5961686472832266	[508]	[350,265,322]	5	hSpCas9	negative selection	1611229
23034648	23034671	14	+	26627737	HeLa	viability after 15 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.8390283961828984	[1160]	[363,227,193]	-6	hSpCas9	negative selection	1611230
23026357	23026380	14	+	26627737	HeLa	viability after 18 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-0.4991605811790316	[569]	[164,78,148]	-4	hSpCas9	negative selection	1693541
23027749	23027772	14	-	26627737	HeLa	viability after 18 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.3778995676769499	[1286]	[567,390,724]	3	hSpCas9	negative selection	1693542
23033349	23033372	14	+	26627737	HeLa	viability after 18 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-1.4324226098400523	[146]	[5,37,10]	-8	hSpCas9	negative selection	1693543
23034641	23034664	14	+	26627737	HeLa	viability after 18 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	0.6184571410801061	[508]	[241,223,322]	5	hSpCas9	negative selection	1693544
23034648	23034671	14	+	26627737	HeLa	viability after 18 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.8241272681398394	[1160]	[246,191,193]	-6	hSpCas9	negative selection	1693545
23026357	23026380	14	+	26627737	HCT116	viability after 6 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	0.9446047683091718	[805]	[210,261]	5	hSpCas9	negative selection	1775856
23027749	23027772	14	-	26627737	HCT116	viability after 6 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	1.5304407752431244	[2124]	[1606,610]	7	hSpCas9	negative selection	1775857
23033349	23033372	14	+	26627737	HCT116	viability after 6 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-0.9178557274786772	[787]	[120,34]	-5	hSpCas9	negative selection	1775858
23034641	23034664	14	+	26627737	HCT116	viability after 6 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	-0.7420376480714909	[1122]	[247,26]	-4	hSpCas9	negative selection	1775859
23034648	23034671	14	+	26627737	HCT116	viability after 6 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.6103935226058321	[1771]	[438,40]	-3	hSpCas9	negative selection	1775860
23026357	23026380	14	+	26627737	HCT116	viability after 8 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-0.18163576546847865	[422]	[208,152,253]	-2	hSpCas9	negative selection	1858171
23027749	23027772	14	-	26627737	HCT116	viability after 8 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.2849668092546054	[860]	[546,478,705]	3	hSpCas9	negative selection	1858172
23033349	23033372	14	+	26627737	HCT116	viability after 8 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	0.3924105775687521	[137]	[119,96,82]	4	hSpCas9	negative selection	1858173
23034641	23034664	14	+	26627737	HCT116	viability after 8 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	0.5373781517862946	[373]	[286,304,304]	5	hSpCas9	negative selection	1858174
23034648	23034671	14	+	26627737	HCT116	viability after 8 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.0850740794671585	[612]	[385,291,278]	-1	hSpCas9	negative selection	1858175
23026357	23026380	14	+	26627737	HCT116	viability after 9 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	0.9230020996445141	[805]	[106,645]	6	hSpCas9	negative selection	1940486
23027749	23027772	14	-	26627737	HCT116	viability after 9 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.09836560853528109	[2124]	[626,591]	0	hSpCas9	negative selection	1940487
23033349	23033372	14	+	26627737	HCT116	viability after 9 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-2.028921982904045	[787]	[112,2]	-8	hSpCas9	negative selection	1940488
23034641	23034664	14	+	26627737	HCT116	viability after 9 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	-0.407685917447804	[1122]	[258,199]	-3	hSpCas9	negative selection	1940489
23034648	23034671	14	+	26627737	HCT116	viability after 9 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.2534725581956281	[1771]	[473,335]	-2	hSpCas9	negative selection	1940490
23026357	23026380	14	+	26627737	HCT116	viability after 12 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-0.4802464196043245	[422]	[224,146,99]	-5	hSpCas9	negative selection	2022801
23027749	23027772	14	-	26627737	HCT116	viability after 12 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.4699413407980275	[860]	[473,645,773]	4	hSpCas9	negative selection	2022802
23033349	23033372	14	+	26627737	HCT116	viability after 12 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	0.25096730184115457	[137]	[115,73,65]	2	hSpCas9	negative selection	2022803
23034641	23034664	14	+	26627737	HCT116	viability after 12 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	0.3371130014082598	[373]	[156,294,301]	3	hSpCas9	negative selection	2022804
23034648	23034671	14	+	26627737	HCT116	viability after 12 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	0.0726810801358353	[612]	[154,440,438]	0	hSpCas9	negative selection	2022805
23026357	23026380	14	+	26627737	HCT116	viability after 15 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-0.575836383202166	[422]	[161,95,229]	-5	hSpCas9	negative selection	2105116
23027749	23027772	14	-	26627737	HCT116	viability after 15 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.612182028697625	[860]	[816,707,749]	5	hSpCas9	negative selection	2105117
23033349	23033372	14	+	26627737	HCT116	viability after 15 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	0.36784017105231903	[137]	[139,35,134]	3	hSpCas9	negative selection	2105118
23034641	23034664	14	+	26627737	HCT116	viability after 15 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	0.7779805596229354	[373]	[421,367,321]	6	hSpCas9	negative selection	2105119
23034648	23034671	14	+	26627737	HCT116	viability after 15 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	0.1028798934050148	[612]	[384,368,380]	1	hSpCas9	negative selection	2105120
23026357	23026380	14	+	26627737	HCT116	viability after 18 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-0.8498270029650108	[422]	[129,92,118]	-7	hSpCas9	negative selection	2187431
23027749	23027772	14	-	26627737	HCT116	viability after 18 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	1.5422646304822267	[860]	[1569,1099,962]	9	hSpCas9	negative selection	2187432
23033349	23033372	14	+	26627737	HCT116	viability after 18 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	1.0387949501164457	[137]	[191,4,226]	7	hSpCas9	negative selection	2187433
23034641	23034664	14	+	26627737	HCT116	viability after 18 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	0.5588817655905085	[373]	[211,314,268]	5	hSpCas9	negative selection	2187434
23034648	23034671	14	+	26627737	HCT116	viability after 18 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	0.05110156505172547	[612]	[324,197,409]	0	hSpCas9	negative selection	2187435
23033388	23033411	14	-	24336569	HL60	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-2.659978791552014	[892]	[298]	-9	hSpCas9	negative selection	2287062
23033416	23033439	14	-	24336569	HL60	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-1.3694761615513105	[1071]	[877]	-8	hSpCas9	negative selection	2287063
23033421	23033444	14	-	24336569	HL60	viability	AACATGGTGTATCAGTACAAAGG	PSMB5	ENSG00000100804	-1.4386932463352848	[1116]	[871]	-8	hSpCas9	negative selection	2287064
23033435	23033458	14	+	24336569	HL60	viability	CACCATGTTGGCAAGCAGTTTGG	PSMB5	ENSG00000100804	-0.1964665755255814	[632]	[1168]	-2	hSpCas9	negative selection	2287065
23033482	23033505	14	-	24336569	HL60	viability	AATCTATGAGCTTCGAAATAAGG	PSMB5	ENSG00000100804	-0.8201360167455058	[140]	[168]	-6	hSpCas9	negative selection	2287066
23033388	23033411	14	-	24336569	KBM7	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-2.70829973654443	[622]	[259]	-9	hSpCas9	negative selection	2354239
23033416	23033439	14	-	24336569	KBM7	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-2.161202606933573	[796]	[485]	-8	hSpCas9	negative selection	2354240
23033421	23033444	14	-	24336569	KBM7	viability	AACATGGTGTATCAGTACAAAGG	PSMB5	ENSG00000100804	-2.5904573221966385	[752]	[340]	-9	hSpCas9	negative selection	2354241
23033435	23033458	14	+	24336569	KBM7	viability	CACCATGTTGGCAAGCAGTTTGG	PSMB5	ENSG00000100804	-0.3563587912099717	[811]	[1729]	-3	hSpCas9	negative selection	2354242
23033482	23033505	14	-	24336569	KBM7	viability	AATCTATGAGCTTCGAAATAAGG	PSMB5	ENSG00000100804	-0.7874291994335072	[161]	[255]	-6	hSpCas9	negative selection	2354243
23035230	23035253	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGCGTGACTGGTTGAAAATCGG	PSMB5	ENSG00000100804	-0.6360774661557603	[38,327]	[13,37]	-3	dCas9-VP64	positive selection	2402072
23018983	23019006	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCTGCCCCCTAG	PSMB5	ENSG00000100804	-1.2513288674205318	[297,436]	[21,46]	-7	dCas9-VP64	positive selection	2446470
23035230	23035253	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGCGTGACTGGTTGAAAATCGG	PSMB5	ENSG00000100804	-0.29742730848723403	[103,190]	[37,38]	-3	dCas9-VP64	positive selection	2497327
23018983	23019006	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCTGCCCCCTAG	PSMB5	ENSG00000100804	0.4244343490827851	[184,278]	[65,133]	3	dCas9-VP64	positive selection	2541725
23033439	23033462	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	-0.5688524228722078	[2,2]	[2,0]	-7	hSpCas9	positive selection	3014321
23026353	23026376	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.24479728133932332	[1,2]	[0,1]	-3	hSpCas9	positive selection	3014322
23026350	23026373	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	-0.6803082574500121	[2,1]	[1,0]	-8	hSpCas9	positive selection	3014323
23026334	23026357	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAAGGGAACCGGATTTCAGGGG	PSMB5	ENSG00000100804	-0.17649736793987264	[2,2]	[3,0]	-3	hSpCas9	positive selection	3014324
23033439	23033462	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	-0.0029407067430559652	[2,2]	[3,0]	0	hSpCas9	positive selection	3082179
23026353	23026376	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.728659669449751	[1,1]	[0,0]	-8	hSpCas9	positive selection	3082180
23026350	23026373	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	-0.22506691957619085	[2,2]	[3,0]	-3	hSpCas9	positive selection	3082181
23026334	23026357	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAAGGGAACCGGATTTCAGGGG	PSMB5	ENSG00000100804	0.18779815297391933	[2,2]	[2,1]	3	hSpCas9	positive selection	3082182
23026164	23026187		-	24336571	A375	resistance to PLX after 7 days	CAGTCAACCTCTACCACGTGCGG	PSMB5	ENSG00000100804	0.10032213051363731	[12,14]	[14,14]	3	hSpCas9	positive selection	3138399
23026361	23026384		-	24336571	A375	resistance to PLX after 7 days	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.5726709014499117	[3,5]	[7,7]	9	hSpCas9	positive selection	3138400
23033664	23033687		-	24336571	A375	resistance to PLX after 7 days	TGATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	0.4489589868690573	[6,7]	[7,11]	9	hSpCas9	positive selection	3138401
23027793	23027816		-	24336571	A375	resistance to PLX after 7 days	TGCTTGAAACCTAAGTCATTTGG	PSMB5	ENSG00000100804	0.03605660247085851	[8,8]	[8,9]	1	hSpCas9	positive selection	3138402
23027762	23027785		-	24336571	A375	resistance to PLX after 7 days	TGTTTTGTGGGTGTGCTGAGAGG	PSMB5	ENSG00000100804	-0.09669088657816571	[7,8]	[7,6]	-3	hSpCas9	positive selection	3138404
23026164	23026187		-	24336571	A375	resistance to PLX after 14 days	CAGTCAACCTCTACCACGTGCGG	PSMB5	ENSG00000100804	0.6177676125028739	[4,7]	[4,4]	5	hSpCas9	positive selection	3196192
23026361	23026384		-	24336571	A375	resistance to PLX after 14 days	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.193779002817689	[5,4]	[2,2]	2	hSpCas9	positive selection	3196193
23033664	23033687		-	24336571	A375	resistance to PLX after 14 days	TGATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	1.6503880048533035	[3,7]	[9,8]	9	hSpCas9	positive selection	3196194
23027793	23027816		-	24336571	A375	resistance to PLX after 14 days	TGCTTGAAACCTAAGTCATTTGG	PSMB5	ENSG00000100804	0.34263281338612017	[8,3]	[4,2]	3	hSpCas9	positive selection	3196195
23027762	23027785		-	24336571	A375	resistance to PLX after 14 days	TGTTTTGTGGGTGTGCTGAGAGG	PSMB5	ENSG00000100804	0.1754104255837123	[11,10]	[5,5]	1	hSpCas9	positive selection	3196197
23026164	23026187		-	24336571	A375	viability after 7 days	CAGTCAACCTCTACCACGTGCGG	PSMB5	ENSG00000100804	-0.24188750825051547	[17]	[12,14]	-3	hSpCas9	negative selection	3253985
23026361	23026384		-	24336571	A375	viability after 7 days	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.7092741771692075	[19]	[3,5]	-9	hSpCas9	negative selection	3253986
23033664	23033687		-	24336571	A375	viability after 7 days	TGATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	-1.897004379352056	[29]	[6,7]	-9	hSpCas9	negative selection	3253987
23027793	23027816		-	24336571	A375	viability after 7 days	TGCTTGAAACCTAAGTCATTTGG	PSMB5	ENSG00000100804	-0.08837204854719682	[9]	[8,8]	-1	hSpCas9	negative selection	3253988
23027762	23027785		-	24336571	A375	viability after 7 days	TGTTTTGTGGGTGTGCTGAGAGG	PSMB5	ENSG00000100804	0.009810414208306972	[8]	[7,8]	0	hSpCas9	negative selection	3253990
23026164	23026187		-	24336571	A375	viability after 14 days	CAGTCAACCTCTACCACGTGCGG	PSMB5	ENSG00000100804	-1.2557838608146816	[17]	[4,7]	-9	hSpCas9	negative selection	3311778
23026361	23026384		-	24336571	A375	viability after 14 days	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.6467454971132516	[19]	[5,4]	-9	hSpCas9	negative selection	3311779
23033664	23033687		-	24336571	A375	viability after 14 days	TGATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	-2.1111904219287334	[29]	[3,7]	-9	hSpCas9	negative selection	3311780
23027793	23027816		-	24336571	A375	viability after 14 days	TGCTTGAAACCTAAGTCATTTGG	PSMB5	ENSG00000100804	-0.4722086091884521	[9]	[8,3]	-5	hSpCas9	negative selection	3311781
23027762	23027785		-	24336571	A375	viability after 14 days	TGTTTTGTGGGTGTGCTGAGAGG	PSMB5	ENSG00000100804	0.47099740228293446	[8]	[11,10]	6	hSpCas9	negative selection	3311783
23026361	23026384	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	3.257326211445835	[15,15]	[0,0]	9	hSpCas9	positive selection	3387975
23033423	23033446	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	3.4499712893882313	[13,13]	[0,0]	9	hSpCas9	positive selection	3387976
23033378	23033401	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-0.21027933863716222	[176,176]	[0,0]	-1	hSpCas9	positive selection	3387977
23033438	23033461	14	+	26780180	HT29	viability (Avana library 4 designs)	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	5.46156509099192	[]	[]	9	hSpCas9	negative selection	3452553
23026352	23026375	14	+	26780180	HT29	viability (Avana library 4 designs)	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	5.66256042100733	[]	[]	9	hSpCas9	negative selection	3452554
23026350	23026373	14	-	26780180	HT29	viability (Avana library 4 designs)	TCTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	5.6868444072025	[]	[]	9	hSpCas9	negative selection	3452555
23026334	23026357	14	-	26780180	HT29	viability (Avana library 4 designs)	TGAAGGGAACCGGATTTCAGGGG	PSMB5	ENSG00000100804	5.76011211750215	[]	[]	9	hSpCas9	negative selection	3452556
23026350	23026373	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	-12.6533897779539	[]	[]	-8	hSpCas9	negative selection	3548982
23033438	23033461	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	-10.8516517385351	[]	[]	-8	hSpCas9	negative selection	3548983
23026352	23026375	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-11.0474480385856	[]	[]	-8	hSpCas9	negative selection	3548984
23026334	23026357	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAAGGGAACCGGATTTCAGGGG	PSMB5	ENSG00000100804	-8.85062226405816	[]	[]	-7	hSpCas9	negative selection	3548985
23033373	23033396	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-10.3070764091037	[]	[]	-8	hSpCas9	negative selection	3548986
23033414	23033437	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTATCAGTACAAAGGCATGGGG	PSMB5	ENSG00000100804	-13.8728277495259	[]	[]	-8	hSpCas9	negative selection	3548987
23026350	23026373	14	-	26780180	A375	viability (Avana lentiGuide)	TCTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	17.218731879358	[]	[]	8	hSpCas9	negative selection	3657641
23033438	23033461	14	+	26780180	A375	viability (Avana lentiGuide)	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	17.2295557013244	[]	[]	8	hSpCas9	negative selection	3657642
23026352	23026375	14	+	26780180	A375	viability (Avana lentiGuide)	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	23.0897586995634	[]	[]	9	hSpCas9	negative selection	3657643
23026334	23026357	14	-	26780180	A375	viability (Avana lentiGuide)	TGAAGGGAACCGGATTTCAGGGG	PSMB5	ENSG00000100804	37.8909900126541	[]	[]	9	hSpCas9	negative selection	3657644
23033373	23033396	14	-	26780180	A375	viability (Avana lentiGuide)	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	32.2626475024389	[]	[]	9	hSpCas9	negative selection	3657645
23033414	23033437	14	-	26780180	A375	viability (Avana lentiGuide)	TGTATCAGTACAAAGGCATGGGG	PSMB5	ENSG00000100804	22.0261809736387	[]	[]	9	hSpCas9	negative selection	3657646
23026350	23026373	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	-0.921308880031708	[5]	[2,2]	-8	hSpCas9	positive selection	3766248
23033438	23033461	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	-0.4751669282248792	[5]	[1,4]	-6	hSpCas9	positive selection	3766249
23026352	23026375	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.4577350681544894	[5]	[1,0]	-9	hSpCas9	positive selection	3766250
23026334	23026357	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAAGGGAACCGGATTTCAGGGG	PSMB5	ENSG00000100804	-0.9923355683149692	[5]	[2,1]	-8	hSpCas9	positive selection	3766251
23033373	23033396	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-0.43814685642806855	[6]	[5,3]	-6	hSpCas9	positive selection	3766252
23033414	23033437	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTATCAGTACAAAGGCATGGGG	PSMB5	ENSG00000100804	-1.6548153082174157	[5]	[0,1]	-9	hSpCas9	positive selection	3766253
23026350	23026373	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	-1.1295559724748045	[5]	[1,1]	-8	hSpCas9	positive selection	3874855
23033438	23033461	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	-2.2704056901029412	[5]	[0,0]	-9	hSpCas9	positive selection	3874856
23026352	23026375	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.8979159654849839	[5]	[0,3]	-8	hSpCas9	positive selection	3874857
23026334	23026357	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAAGGGAACCGGATTTCAGGGG	PSMB5	ENSG00000100804	-0.8754963011361014	[6]	[1,3]	-8	hSpCas9	positive selection	3874858
23033373	23033396	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-0.9596471955176314	[6]	[0,3]	-8	hSpCas9	positive selection	3874859
23033414	23033437	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTATCAGTACAAAGGCATGGGG	PSMB5	ENSG00000100804	-1.23457899214722	[5]	[2,0]	-9	hSpCas9	positive selection	3874860
23034818	23034841	14	+	26780180	A375	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	1.10961832011364	[]	[]	5	hSpCas9	negative selection	3985293
23034860	23034883	14	-	26780180	A375	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	1.43992248491416	[]	[]	8	hSpCas9	negative selection	3985294
23033378	23033401	14	+	26780180	A375	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	2.37246931557477	[]	[]	9	hSpCas9	negative selection	3985295
23026352	23026375	14	+	26780180	A375	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	2.36257963268752	[]	[]	9	hSpCas9	negative selection	3985296
23026361	23026384	14	-	26780180	A375	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	1.59025799725819	[]	[]	8	hSpCas9	negative selection	3985297
23033423	23033446	14	+	26780180	A375	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	1.82978388613425	[]	[]	9	hSpCas9	negative selection	3985298
23034818	23034841	14	+	26780180	HT29	viability (GeCKOv2 library)	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	1.80512204275749	[]	[]	8	hSpCas9	negative selection	4093259
23034860	23034883	14	-	26780180	HT29	viability (GeCKOv2 library)	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	1.17335838013369	[]	[]	5	hSpCas9	negative selection	4093260
23033378	23033401	14	+	26780180	HT29	viability (GeCKOv2 library)	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	3.04962695821025	[]	[]	9	hSpCas9	negative selection	4093261
23026352	23026375	14	+	26780180	HT29	viability (GeCKOv2 library)	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	3.42461853210579	[]	[]	9	hSpCas9	negative selection	4093262
23026361	23026384	14	-	26780180	HT29	viability (GeCKOv2 library)	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	2.38207271489082	[]	[]	9	hSpCas9	negative selection	4093263
23033423	23033446	14	+	26780180	HT29	viability (GeCKOv2 library)	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	2.66484385825437	[]	[]	9	hSpCas9	negative selection	4093264
23026164	23026187	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGTCAACCTCTACCACGTGCGG	PSMB5	ENSG00000100804	-0.3019122995034813	[4]	[1,2]	-6	hSpCas9	positive selection	4163625
23026361	23026384	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.4876772437224295	[3]	[1,1]	-8	hSpCas9	positive selection	4163628
23033664	23033687	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	-0.020044645403230282	[3]	[0,3]	0	hSpCas9	positive selection	4163629
23027793	23027816	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCTTGAAACCTAAGTCATTTGG	PSMB5	ENSG00000100804	-0.016821085836681182	[2]	[1,1]	0	hSpCas9	positive selection	4163630
23027762	23027785	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTTTTGTGGGTGTGCTGAGAGG	PSMB5	ENSG00000100804	0.04080877074688988	[3]	[1,2]	1	hSpCas9	positive selection	4163632
23026164	23026187	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGTCAACCTCTACCACGTGCGG	PSMB5	ENSG00000100804	-0.016949890512855392	[4]	[2,3,1,0]	0	hSpCas9	positive selection	4227647
23026361	23026384	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	1.1449139494032645	[3]	[0,3,1,4]	8	hSpCas9	positive selection	4227650
23033664	23033687	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	1.0364272666870387	[3]	[2,4,2,3]	7	hSpCas9	positive selection	4227651
23027793	23027816	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCTTGAAACCTAAGTCATTTGG	PSMB5	ENSG00000100804	-0.6528636727272601	[2]	[0,0,0,0]	-8	hSpCas9	positive selection	4227652
23027762	23027785	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTTTTGTGGGTGTGCTGAGAGG	PSMB5	ENSG00000100804	1.1593485664672103	[2]	[4,3,3,0]	8	hSpCas9	positive selection	4227654
23034818	23034841	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.9632435477152176	[1]	[0,0]	-9	hSpCas9	positive selection	4292744
23026352	23026375	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.6903560041912783	[3]	[2,0]	-9	hSpCas9	positive selection	4292745
23034860	23034883	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.2877086884472459	[2]	[2,0]	-5	hSpCas9	positive selection	4292746
23026361	23026384	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.0648534834124317	[2]	[0,0]	-9	hSpCas9	positive selection	4357003
23033423	23033446	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.1119390393978066	[2]	[0,0]	-9	hSpCas9	positive selection	4357004
23033378	23033401	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-0.26051040593079916	[4]	[2,2]	-5	hSpCas9	positive selection	4357005
23026279	23026301	14	-	27760321	OCIAML3	viability	CATATGGGGTCATGGATCGGGG	PSMB5	ENSG00000100804	-0.23896953878484697	[640,561]	[392,403]	-3	hSpCas9	negative selection	4431395
23026326	23026348	14	+	27760321	OCIAML3	viability	GAAGGTGGCCCCTGAAATCCGG	PSMB5	ENSG00000100804	-0.1071374263840939	[412,318]	[209,333]	-1	hSpCas9	negative selection	4431396
23026350	23026372	14	-	27760321	OCIAML3	viability	CTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	0.3953566094438833	[340,323]	[285,415]	5	hSpCas9	negative selection	4431397
23033373	23033395	14	-	27760321	OCIAML3	viability	TCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	0.008581707737322142	[286,254]	[244,170]	0	hSpCas9	negative selection	4431398
23033415	23033437	14	-	27760321	OCIAML3	viability	TGTATCAGTACAAAGGCATGGG	PSMB5	ENSG00000100804	0.4556471943971123	[81,84]	[79,102]	5	hSpCas9	negative selection	4431399
23033639	23033661	14	-	27760321	OCIAML3	viability	CATAGTTGCAGCTGACTCCAGG	PSMB5	ENSG00000100804	0.06335361293608277	[773,590]	[384,772]	0	hSpCas9	negative selection	4431400
23033664	23033686	14	-	27760321	OCIAML3	viability	GATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	0.07946235113784128	[711,571]	[418,668]	0	hSpCas9	negative selection	4431401
23034767	23034789	14	+	27760321	OCIAML3	viability	GACCATCACTGAGACTCCCTGG	PSMB5	ENSG00000100804	0.9418488788868211	[494,422]	[620,773]	9	hSpCas9	negative selection	4431402
23026279	23026301	14	-	27760321	OCIAML2	viability	CATATGGGGTCATGGATCGGGG	PSMB5	ENSG00000100804	0.49262092807529007	[640,561]	[488,938]	6	hSpCas9	negative selection	4514858
23026326	23026348	14	+	27760321	OCIAML2	viability	GAAGGTGGCCCCTGAAATCCGG	PSMB5	ENSG00000100804	-0.1378342599857929	[412,318]	[182,377]	-2	hSpCas9	negative selection	4514859
23026350	23026372	14	-	27760321	OCIAML2	viability	CTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	0.8740896504697496	[340,323]	[449,550]	9	hSpCas9	negative selection	4514860
23033373	23033395	14	-	27760321	OCIAML2	viability	TCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-0.2132855115590938	[286,254]	[133,260]	-3	hSpCas9	negative selection	4514861
23033415	23033437	14	-	27760321	OCIAML2	viability	TGTATCAGTACAAAGGCATGGG	PSMB5	ENSG00000100804	0.4908798507455905	[81,84]	[81,112]	6	hSpCas9	negative selection	4514862
23033639	23033661	14	-	27760321	OCIAML2	viability	CATAGTTGCAGCTGACTCCAGG	PSMB5	ENSG00000100804	0.13039199322988382	[773,590]	[521,701]	1	hSpCas9	negative selection	4514863
23033664	23033686	14	-	27760321	OCIAML2	viability	GATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	0.18646037381668068	[711,571]	[553,631]	2	hSpCas9	negative selection	4514864
23034767	23034789	14	+	27760321	OCIAML2	viability	GACCATCACTGAGACTCCCTGG	PSMB5	ENSG00000100804	0.4191048164498714	[494,422]	[506,478]	6	hSpCas9	negative selection	4514865
23026279	23026301	14	-	27760321	MV411	viability	CATATGGGGTCATGGATCGGGG	PSMB5	ENSG00000100804	0.2030325766822207	[640,561]	[395,545]	1	hSpCas9	negative selection	4598321
23026326	23026348	14	+	27760321	MV411	viability	GAAGGTGGCCCCTGAAATCCGG	PSMB5	ENSG00000100804	-0.5835551703525736	[412,318]	[163,153]	-4	hSpCas9	negative selection	4598322
23026350	23026372	14	-	27760321	MV411	viability	CTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	0.21193733356809477	[340,323]	[301,182]	1	hSpCas9	negative selection	4598323
23033373	23033395	14	-	27760321	MV411	viability	TCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-0.43433495740715944	[286,254]	[54,247]	-3	hSpCas9	negative selection	4598324
23033415	23033437	14	-	27760321	MV411	viability	TGTATCAGTACAAAGGCATGGG	PSMB5	ENSG00000100804	-0.10765309586149074	[81,84]	[30,81]	-1	hSpCas9	negative selection	4598325
23033639	23033661	14	-	27760321	MV411	viability	CATAGTTGCAGCTGACTCCAGG	PSMB5	ENSG00000100804	-0.6511232787811738	[773,590]	[262,316]	-4	hSpCas9	negative selection	4598326
23033664	23033686	14	-	27760321	MV411	viability	GATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	-0.5241227806348985	[711,571]	[212,412]	-4	hSpCas9	negative selection	4598327
23034767	23034789	14	+	27760321	MV411	viability	GACCATCACTGAGACTCCCTGG	PSMB5	ENSG00000100804	-0.16111240325286091	[494,422]	[70,568]	-1	hSpCas9	negative selection	4598328
23026279	23026301	14	-	27760321	HL60	viability	CATATGGGGTCATGGATCGGGG	PSMB5	ENSG00000100804	0.20884670539050382	[640,561]	[572,559]	2	hSpCas9	negative selection	4681784
23026326	23026348	14	+	27760321	HL60	viability	GAAGGTGGCCCCTGAAATCCGG	PSMB5	ENSG00000100804	-0.732267905549767	[412,318]	[150,207]	-6	hSpCas9	negative selection	4681785
23026350	23026372	14	-	27760321	HL60	viability	CTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	0.27334534645418074	[340,323]	[333,322]	3	hSpCas9	negative selection	4681786
23033373	23033395	14	-	27760321	HL60	viability	TCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	0.23817823913734232	[286,254]	[283,235]	3	hSpCas9	negative selection	4681787
23033415	23033437	14	-	27760321	HL60	viability	TGTATCAGTACAAAGGCATGGG	PSMB5	ENSG00000100804	-1.091406706638748	[81,84]	[20,43]	-8	hSpCas9	negative selection	4681788
23033639	23033661	14	-	27760321	HL60	viability	CATAGTTGCAGCTGACTCCAGG	PSMB5	ENSG00000100804	0.260296251461444	[773,590]	[698,623]	3	hSpCas9	negative selection	4681789
23033664	23033686	14	-	27760321	HL60	viability	GATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	0.13595765928204007	[711,571]	[489,660]	1	hSpCas9	negative selection	4681790
23034767	23034789	14	+	27760321	HL60	viability	GACCATCACTGAGACTCCCTGG	PSMB5	ENSG00000100804	0.5654461282836718	[494,422]	[589,513]	6	hSpCas9	negative selection	4681791
23026279	23026301	14	-	27760321	HT1080	viability	CATATGGGGTCATGGATCGGGG	PSMB5	ENSG00000100804	-7.639486431506597	[561,438]	[0,0]	-9	hSpCas9	negative selection	4765247
23026326	23026348	14	+	27760321	HT1080	viability	GAAGGTGGCCCCTGAAATCCGG	PSMB5	ENSG00000100804	-6.215359046113278	[318,248]	[1,0]	-9	hSpCas9	negative selection	4765248
23026350	23026372	14	-	27760321	HT1080	viability	CTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	-6.844656284406258	[323,252]	[0,0]	-9	hSpCas9	negative selection	4765249
23033373	23033395	14	-	27760321	HT1080	viability	TCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-5.498723265684355	[254,198]	[1,1]	-8	hSpCas9	negative selection	4765250
23033415	23033437	14	-	27760321	HT1080	viability	TGTATCAGTACAAAGGCATGGG	PSMB5	ENSG00000100804	-3.2931121531852963	[84,66]	[4,0]	-7	hSpCas9	negative selection	4765251
23033639	23033661	14	-	27760321	HT1080	viability	CATAGTTGCAGCTGACTCCAGG	PSMB5	ENSG00000100804	-7.711052758975358	[590,460]	[0,0]	-9	hSpCas9	negative selection	4765252
23033664	23033686	14	-	27760321	HT1080	viability	GATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	-7.665236197782858	[571,446]	[0,0]	-9	hSpCas9	negative selection	4765253
23034767	23034789	14	+	27760321	HT1080	viability	GACCATCACTGAGACTCCCTGG	PSMB5	ENSG00000100804	-2.5181937130312337	[422,329]	[29,21]	-7	hSpCas9	negative selection	4765254
23026279	23026301	14	-	27760321	HT29	viability after 7 days	CATATGGGGTCATGGATCGGGG	PSMB5	ENSG00000100804	-3.2067680360068214	[561,438]	[74,40,92]	-9	hSpCas9	negative selection	4848710
23026326	23026348	14	+	27760321	HT29	viability after 7 days	GAAGGTGGCCCCTGAAATCCGG	PSMB5	ENSG00000100804	-4.5961523050165205	[318,248]	[7,12,22]	-9	hSpCas9	negative selection	4848711
23026350	23026372	14	-	27760321	HT29	viability after 7 days	CTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	-3.9157725782642365	[323,252]	[12,32,25]	-9	hSpCas9	negative selection	4848712
23033373	23033395	14	-	27760321	HT29	viability after 7 days	TCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-2.7920805866737917	[254,198]	[35,63,25]	-9	hSpCas9	negative selection	4848713
23033415	23033437	14	-	27760321	HT29	viability after 7 days	TGTATCAGTACAAAGGCATGGG	PSMB5	ENSG00000100804	-3.0284567886573175	[84,66]	[30,6,0]	-9	hSpCas9	negative selection	4848714
23033639	23033661	14	-	27760321	HT29	viability after 7 days	CATAGTTGCAGCTGACTCCAGG	PSMB5	ENSG00000100804	-2.4559984207995122	[590,460]	[65,190,104]	-9	hSpCas9	negative selection	4848715
23033664	23033686	14	-	27760321	HT29	viability after 7 days	GATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	-4.313127236327265	[571,446]	[38,5,53]	-9	hSpCas9	negative selection	4848716
23034767	23034789	14	+	27760321	HT29	viability after 7 days	GACCATCACTGAGACTCCCTGG	PSMB5	ENSG00000100804	-0.9717892222402137	[422,329]	[310,247,191]	-8	hSpCas9	negative selection	4848717
23026279	23026301	14	-	27760321	HT29	viability after 25 days	CATATGGGGTCATGGATCGGGG	PSMB5	ENSG00000100804	-6.258774367027	[561,438]	[18,0,0]	-9	hSpCas9	negative selection	4932173
23026326	23026348	14	+	27760321	HT29	viability after 25 days	GAAGGTGGCCCCTGAAATCCGG	PSMB5	ENSG00000100804	-8.341623853784712	[318,248]	[0,0,0]	-9	hSpCas9	negative selection	4932174
23026350	23026372	14	-	27760321	HT29	viability after 25 days	CTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	-4.538544308532399	[323,252]	[0,39,0]	-9	hSpCas9	negative selection	4932175
23033373	23033395	14	-	27760321	HT29	viability after 25 days	TCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-6.471309829938574	[254,198]	[0,3,3]	-9	hSpCas9	negative selection	4932176
23033415	23033437	14	-	27760321	HT29	viability after 25 days	TGTATCAGTACAAAGGCATGGG	PSMB5	ENSG00000100804	-3.1008742355488694	[84,66]	[0,27,0]	-8	hSpCas9	negative selection	4932177
23033639	23033661	14	-	27760321	HT29	viability after 25 days	CATAGTTGCAGCTGACTCCAGG	PSMB5	ENSG00000100804	-9.23073502382188	[590,460]	[0,0,0]	-9	hSpCas9	negative selection	4932178
23033664	23033686	14	-	27760321	HT29	viability after 25 days	GATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	-9.184918462629382	[571,446]	[0,0,0]	-9	hSpCas9	negative selection	4932179
23034767	23034789	14	+	27760321	HT29	viability after 25 days	GACCATCACTGAGACTCCCTGG	PSMB5	ENSG00000100804	-2.4828431423346897	[422,329]	[73,53,105]	-8	hSpCas9	negative selection	4932180
23026279	23026301	14	-	27760321	HT29	viability after 22 days	CATATGGGGTCATGGATCGGGG	PSMB5	ENSG00000100804	-7.958897117942924	[561,438]	[0,4,0]	-9	hSpCas9	negative selection	5015636
23026326	23026348	14	+	27760321	HT29	viability after 22 days	GAAGGTGGCCCCTGAAATCCGG	PSMB5	ENSG00000100804	-8.358942485643972	[318,248]	[0,0,0]	-9	hSpCas9	negative selection	5015637
23026350	23026372	14	-	27760321	HT29	viability after 22 days	CTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	-6.272648209871707	[323,252]	[0,10,0]	-9	hSpCas9	negative selection	5015638
23033373	23033395	14	-	27760321	HT29	viability after 22 days	TCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-4.683376489091008	[254,198]	[0,7,21]	-9	hSpCas9	negative selection	5015639
23033415	23033437	14	-	27760321	HT29	viability after 22 days	TGTATCAGTACAAAGGCATGGG	PSMB5	ENSG00000100804	-2.8894319419724734	[84,66]	[29,3,0]	-8	hSpCas9	negative selection	5015640
23033639	23033661	14	-	27760321	HT29	viability after 22 days	CATAGTTGCAGCTGACTCCAGG	PSMB5	ENSG00000100804	-6.257692831303439	[590,460]	[0,17,4]	-9	hSpCas9	negative selection	5015641
23033664	23033686	14	-	27760321	HT29	viability after 22 days	GATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	-9.202237094488641	[571,446]	[0,0,0]	-9	hSpCas9	negative selection	5015642
23034767	23034789	14	+	27760321	HT29	viability after 22 days	GACCATCACTGAGACTCCCTGG	PSMB5	ENSG00000100804	-1.7130345193237257	[422,329]	[126,77,193]	-8	hSpCas9	negative selection	5015643
23026279	23026301	14	-	27760321	HT29	viability after 19 days	CATATGGGGTCATGGATCGGGG	PSMB5	ENSG00000100804	-6.957027205231182	[561,438]	[4,7,0]	-9	hSpCas9	negative selection	5099099
23026326	23026348	14	+	27760321	HT29	viability after 19 days	GAAGGTGGCCCCTGAAATCCGG	PSMB5	ENSG00000100804	-8.343102433220759	[318,248]	[0,0,0]	-9	hSpCas9	negative selection	5099100
23026350	23026372	14	-	27760321	HT29	viability after 19 days	CTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	-7.928555094867502	[323,252]	[0,0,1]	-9	hSpCas9	negative selection	5099101
23033373	23033395	14	-	27760321	HT29	viability after 19 days	TCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-4.417556496784761	[254,198]	[11,0,22]	-9	hSpCas9	negative selection	5099102
23033415	23033437	14	-	27760321	HT29	viability after 19 days	TGTATCAGTACAAAGGCATGGG	PSMB5	ENSG00000100804	-6.4421563650932425	[84,66]	[0,0,0]	-9	hSpCas9	negative selection	5099103
23033639	23033661	14	-	27760321	HT29	viability after 19 days	CATAGTTGCAGCTGACTCCAGG	PSMB5	ENSG00000100804	-4.214797467013104	[590,460]	[1,59,31]	-9	hSpCas9	negative selection	5099104
23033664	23033686	14	-	27760321	HT29	viability after 19 days	GATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	-8.749135008244101	[571,446]	[0,0,1]	-9	hSpCas9	negative selection	5099105
23034767	23034789	14	+	27760321	HT29	viability after 19 days	GACCATCACTGAGACTCCCTGG	PSMB5	ENSG00000100804	-1.3418695284235522	[422,329]	[176,156,175]	-7	hSpCas9	negative selection	5099106
23026279	23026301	14	-	27760321	HT29	viability after 16 days	CATATGGGGTCATGGATCGGGG	PSMB5	ENSG00000100804	-7.090402717422887	[561,438]	[1,8,0]	-9	hSpCas9	negative selection	5182562
23026326	23026348	14	+	27760321	HT29	viability after 16 days	GAAGGTGGCCCCTGAAATCCGG	PSMB5	ENSG00000100804	-8.311637980799837	[318,248]	[0,0,0]	-9	hSpCas9	negative selection	5182563
23026350	23026372	14	-	27760321	HT29	viability after 16 days	CTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	-8.334352676267907	[323,252]	[0,0,0]	-9	hSpCas9	negative selection	5182564
23033373	23033395	14	-	27760321	HT29	viability after 16 days	TCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-3.908962952899764	[254,198]	[3,35,8]	-9	hSpCas9	negative selection	5182565
23033415	23033437	14	-	27760321	HT29	viability after 16 days	TGTATCAGTACAAAGGCATGGG	PSMB5	ENSG00000100804	-6.022357156505644	[84,66]	[1,0,0]	-9	hSpCas9	negative selection	5182566
23033639	23033661	14	-	27760321	HT29	viability after 16 days	CATAGTTGCAGCTGACTCCAGG	PSMB5	ENSG00000100804	-8.767776695178156	[590,460]	[0,1,0]	-9	hSpCas9	negative selection	5182567
23033664	23033686	14	-	27760321	HT29	viability after 16 days	GATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	-7.719021225860121	[571,446]	[0,0,5]	-9	hSpCas9	negative selection	5182568
23034767	23034789	14	+	27760321	HT29	viability after 16 days	GACCATCACTGAGACTCCCTGG	PSMB5	ENSG00000100804	-1.3888856320697331	[422,329]	[155,162,162]	-7	hSpCas9	negative selection	5182569
23026279	23026301	14	-	27760321	HT29	viability after 13 days	CATATGGGGTCATGGATCGGGG	PSMB5	ENSG00000100804	-4.332683986827754	[561,438]	[0,64,20]	-9	hSpCas9	negative selection	5266025
23026326	23026348	14	+	27760321	HT29	viability after 13 days	GAAGGTGGCCCCTGAAATCCGG	PSMB5	ENSG00000100804	-8.363925380243975	[318,248]	[0,0,0]	-9	hSpCas9	negative selection	5266026
23026350	23026372	14	-	27760321	HT29	viability after 13 days	CTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	-7.358129201503117	[323,252]	[0,0,3]	-9	hSpCas9	negative selection	5266027
23033373	23033395	14	-	27760321	HT29	viability after 13 days	TCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-1.9963989866277987	[254,198]	[9,85,99]	-8	hSpCas9	negative selection	5266028
23033415	23033437	14	-	27760321	HT29	viability after 13 days	TGTATCAGTACAAAGGCATGGG	PSMB5	ENSG00000100804	-5.737577723736263	[84,66]	[1,1,0]	-9	hSpCas9	negative selection	5266029
23033639	23033661	14	-	27760321	HT29	viability after 13 days	CATAGTTGCAGCTGACTCCAGG	PSMB5	ENSG00000100804	-4.2791457790245	[590,460]	[1,54,36]	-9	hSpCas9	negative selection	5266030
23033664	23033686	14	-	27760321	HT29	viability after 13 days	GATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	-8.777856624037303	[571,446]	[0,0,1]	-9	hSpCas9	negative selection	5266031
23034767	23034789	14	+	27760321	HT29	viability after 13 days	GACCATCACTGAGACTCCCTGG	PSMB5	ENSG00000100804	-2.103241738575283	[422,329]	[90,112,100]	-8	hSpCas9	negative selection	5266032
23026279	23026301	14	-	27760321	HT29	viability after 10 days	CATATGGGGTCATGGATCGGGG	PSMB5	ENSG00000100804	-4.80217996910962	[561,438]	[27,15,22]	-9	hSpCas9	negative selection	5349488
23026326	23026348	14	+	27760321	HT29	viability after 10 days	GAAGGTGGCCCCTGAAATCCGG	PSMB5	ENSG00000100804	-4.939153533649727	[318,248]	[4,0,27]	-9	hSpCas9	negative selection	5349489
23026350	23026372	14	-	27760321	HT29	viability after 10 days	CTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	-7.292236931483	[323,252]	[0,4,0]	-9	hSpCas9	negative selection	5349490
23033373	23033395	14	-	27760321	HT29	viability after 10 days	TCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-4.427016509199918	[254,198]	[16,20,1]	-9	hSpCas9	negative selection	5349491
23033415	23033437	14	-	27760321	HT29	viability after 10 days	TGTATCAGTACAAAGGCATGGG	PSMB5	ENSG00000100804	-2.630631539603466	[84,66]	[40,3,0]	-9	hSpCas9	negative selection	5349492
23033639	23033661	14	-	27760321	HT29	viability after 10 days	CATAGTTGCAGCTGACTCCAGG	PSMB5	ENSG00000100804	-5.532840061078206	[590,460]	[18,20,2]	-9	hSpCas9	negative selection	5349493
23033664	23033686	14	-	27760321	HT29	viability after 10 days	GATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	-8.311938706121241	[571,446]	[3,0,0]	-9	hSpCas9	negative selection	5349494
23034767	23034789	14	+	27760321	HT29	viability after 10 days	GACCATCACTGAGACTCCCTGG	PSMB5	ENSG00000100804	-0.7649299215025946	[422,329]	[291,252,283]	-7	hSpCas9	negative selection	5349495
23026279	23026301	14	-	27760321	MOLM13	viability	CATATGGGGTCATGGATCGGGG	PSMB5	ENSG00000100804	-0.8538546796812916	[640,561]	[336,59]	-5	hSpCas9	negative selection	5432951
23026326	23026348	14	+	27760321	MOLM13	viability	GAAGGTGGCCCCTGAAATCCGG	PSMB5	ENSG00000100804	-0.2768637518519138	[412,318]	[31,285]	-2	hSpCas9	negative selection	5432952
23026350	23026372	14	-	27760321	MOLM13	viability	CTACTACGTGGACAGTGAAGGG	PSMB5	ENSG00000100804	0.34787620888346016	[340,323]	[130,330]	2	hSpCas9	negative selection	5432953
23033373	23033395	14	-	27760321	MOLM13	viability	TCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-1.6806474510567142	[286,254]	[45,48]	-7	hSpCas9	negative selection	5432954
23033415	23033437	14	-	27760321	MOLM13	viability	TGTATCAGTACAAAGGCATGGG	PSMB5	ENSG00000100804	-2.8603725246822673	[81,84]	[12,0]	-8	hSpCas9	negative selection	5432955
23033639	23033661	14	-	27760321	MOLM13	viability	CATAGTTGCAGCTGACTCCAGG	PSMB5	ENSG00000100804	0.3007389529663592	[773,590]	[239,666]	2	hSpCas9	negative selection	5432956
23033664	23033686	14	-	27760321	MOLM13	viability	GATCTTAACAGTTCCGCCATGG	PSMB5	ENSG00000100804	-0.6504488004646549	[711,571]	[256,205]	-4	hSpCas9	negative selection	5432957
23034767	23034789	14	+	27760321	MOLM13	viability	GACCATCACTGAGACTCCCTGG	PSMB5	ENSG00000100804	1.0055561394333585	[494,422]	[621,429]	7	hSpCas9	negative selection	5432958
23034870	23034893	14	+	27661255	K562	viability	GGCAAGCGCCATGTCTAGTGTGG	PSMB5	ENSG00000100804	-1.2653255343888898	[606,458]	[204,154]	-8	dCas9-KRAB	negative selection	5504837
23034443	23034466	14	-	27661255	K562	viability	GGAGGAAGGTGAGGCCTCTTGGG	PSMB5	ENSG00000100804	-2.035387815866737	[526,442]	[110,80]	-9	dCas9-KRAB	negative selection	5504838
23034461	23034484	14	-	27661255	K562	viability	GGCCGGGGGTAAGTCGGGGGAGG	PSMB5	ENSG00000100804	-1.3438454698597835	[263,323]	[109,76]	-9	dCas9-KRAB	negative selection	5504839
23034818	23034841	14	+	27260156	BXPC3	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.17142382838228576	[124]	[48,99,161,167]	-4	hSpCas9	negative selection	5565204
23026352	23026375	14	+	27260156	BXPC3	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.0232627204699678	[608]	[248,308,260,455]	-9	hSpCas9	negative selection	5565205
23034860	23034883	14	-	27260156	BXPC3	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.19891298382747502	[388]	[246,361,358,472]	-4	hSpCas9	negative selection	5565206
23026361	23026384	14	-	27260156	BXPC3	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.5626379286491796	[239]	[89,62,87,100]	-9	hSpCas9	negative selection	5629463
23033423	23033446	14	+	27260156	BXPC3	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-2.0586865263718312	[344]	[120,57,48,118]	-9	hSpCas9	negative selection	5629464
23033378	23033401	14	+	27260156	BXPC3	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.1938514113748482	[1187]	[484,574,577,533]	-9	hSpCas9	negative selection	5629465
23034818	23034841	14	+	27260156	A673	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.2107676529843019	[124]	[139,106,174,95]	-5	hSpCas9	negative selection	5686455
23026352	23026375	14	+	27260156	A673	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.7107975771354793	[608]	[453,451,419,461]	-9	hSpCas9	negative selection	5686456
23034860	23034883	14	-	27260156	A673	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.3136844899938851	[388]	[400,397,318,387]	-6	hSpCas9	negative selection	5686457
23026361	23026384	14	-	27260156	A673	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.6282475707486075	[239]	[176,140,181,248]	-9	hSpCas9	negative selection	5750714
23033423	23033446	14	+	27260156	A673	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.266122005304923	[344]	[202,137,193,156]	-9	hSpCas9	negative selection	5750715
23033378	23033401	14	+	27260156	A673	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-0.8535182214849626	[1187]	[982,696,663,840]	-9	hSpCas9	negative selection	5750716
23034818	23034841	14	+	27260156	A375	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-1.048737340134552	[124]	[54,100,85,46]	-8	hSpCas9	negative selection	5807706
23026352	23026375	14	+	27260156	A375	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.7461029713165805	[608]	[48,304,125,360]	-9	hSpCas9	negative selection	5807707
23034860	23034883	14	-	27260156	A375	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-1.265454861332027	[388]	[147,274,238,113]	-8	hSpCas9	negative selection	5807708
23026361	23026384	14	-	27260156	A375	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-2.3599408146763636	[239]	[40,12,72,81]	-9	hSpCas9	negative selection	5871965
23033423	23033446	14	+	27260156	A375	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-2.503208427608708	[344]	[76,107,58,47]	-9	hSpCas9	negative selection	5871966
23033378	23033401	14	+	27260156	A375	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-2.140401737367757	[1187]	[360,229,282,365]	-9	hSpCas9	negative selection	5871967
23034818	23034841	14	+	27260156	COLO741	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.7239268270492016	[124]	[66,89,127]	-9	hSpCas9	negative selection	5928957
23026352	23026375	14	+	27260156	COLO741	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.2081970287374573	[608]	[344,296,365]	-9	hSpCas9	negative selection	5928958
23034860	23034883	14	-	27260156	COLO741	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.08964625537155468	[388]	[445,478,472]	-2	hSpCas9	negative selection	5928959
23026361	23026384	14	-	27260156	COLO741	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.8163933131678252	[239]	[198,149,174]	-9	hSpCas9	negative selection	5993216
23033423	23033446	14	+	27260156	COLO741	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.8766633913592339	[344]	[170,113,81]	-9	hSpCas9	negative selection	5993217
23033378	23033401	14	+	27260156	COLO741	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.1965730338338254	[1187]	[654,642,684]	-9	hSpCas9	negative selection	5993218
23034818	23034841	14	+	27260156	CAL120	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-1.7202193555593368	[124]	[28,69,39]	-9	hSpCas9	negative selection	6050208
23026352	23026375	14	+	27260156	CAL120	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-2.3486433224804233	[608]	[174,168,106]	-9	hSpCas9	negative selection	6050209
23034860	23034883	14	-	27260156	CAL120	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.700618526322201	[388]	[280,373,236]	-7	hSpCas9	negative selection	6050210
23026361	23026384	14	-	27260156	CAL120	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-2.1673278127285567	[239]	[71,102,25]	-9	hSpCas9	negative selection	6114467
23033423	23033446	14	+	27260156	CAL120	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-2.7017067562760833	[344]	[54,114,26]	-9	hSpCas9	negative selection	6114468
23033378	23033401	14	+	27260156	CAL120	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.9868770887020968	[1187]	[262,511,327]	-9	hSpCas9	negative selection	6114469
23034818	23034841	14	+	27260156	CADOES1	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.8984349625805996	[124]	[71,52,72,50]	-9	hSpCas9	negative selection	6171459
23026352	23026375	14	+	27260156	CADOES1	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.745702097211626	[608]	[386,335,265,362]	-8	hSpCas9	negative selection	6171460
23034860	23034883	14	-	27260156	CADOES1	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.4918814753303731	[388]	[315,220,230,260]	-7	hSpCas9	negative selection	6171461
23026361	23026384	14	-	27260156	CADOES1	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.3276063488150436	[239]	[81,112,117,40]	-9	hSpCas9	negative selection	6235718
23033423	23033446	14	+	27260156	CADOES1	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.5469769191438594	[344]	[132,65,106,133]	-9	hSpCas9	negative selection	6235719
23033378	23033401	14	+	27260156	CADOES1	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.3681797525779238	[1187]	[442,434,432,399]	-9	hSpCas9	negative selection	6235720
23034818	23034841	14	+	27260156	EWS502	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-1.065748801677755	[124]	[39,82,49,82]	-9	hSpCas9	negative selection	6292710
23026352	23026375	14	+	27260156	EWS502	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.772294240465501	[608]	[111,255,242,147]	-9	hSpCas9	negative selection	6292711
23034860	23034883	14	-	27260156	EWS502	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.4967087572384833	[388]	[224,375,268,301]	-7	hSpCas9	negative selection	6292712
23026361	23026384	14	-	27260156	EWS502	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-2.4404863169554734	[239]	[31,83,25,44]	-9	hSpCas9	negative selection	6356969
23033423	23033446	14	+	27260156	EWS502	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-2.733491209730926	[344]	[116,22,14,57]	-9	hSpCas9	negative selection	6356970
23033378	23033401	14	+	27260156	EWS502	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.856153164371617	[1187]	[245,347,328,487]	-9	hSpCas9	negative selection	6356971
23034818	23034841	14	+	27260156	EW8	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.7015266677376895	[124]	[72,51,62,61]	-8	hSpCas9	negative selection	6413961
23026352	23026375	14	+	27260156	EW8	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.153241392847684	[608]	[263,130,179,322]	-9	hSpCas9	negative selection	6413962
23034860	23034883	14	-	27260156	EW8	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.7149732694114614	[388]	[339,207,104,145]	-8	hSpCas9	negative selection	6413963
23026361	23026384	14	-	27260156	EW8	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.2677313469586606	[239]	[99,57,79,86]	-9	hSpCas9	negative selection	6478220
23033423	23033446	14	+	27260156	EW8	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.8787384853481728	[344]	[127,63,85,29]	-9	hSpCas9	negative selection	6478221
23033378	23033401	14	+	27260156	EW8	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.0600840310675885	[1187]	[723,368,422,364]	-9	hSpCas9	negative selection	6478222
23034818	23034841	14	+	27260156	CORL105	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.32182884395731115	[124]	[161,94,89,118]	-5	hSpCas9	negative selection	6535212
23026352	23026375	14	+	27260156	CORL105	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.44420021368248375	[608]	[450,559,595,496]	-7	hSpCas9	negative selection	6535213
23034860	23034883	14	-	27260156	CORL105	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.045182095253950005	[388]	[448,294,579,465]	-1	hSpCas9	negative selection	6535214
23026361	23026384	14	-	27260156	CORL105	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.26073321459351695	[239]	[224,403,448,280]	5	hSpCas9	negative selection	6599471
23033423	23033446	14	+	27260156	CORL105	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.3102441816959722	[344]	[160,193,169,126]	-9	hSpCas9	negative selection	6599472
23033378	23033401	14	+	27260156	CORL105	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-0.7319446836769803	[1187]	[749,1108,895,595]	-8	hSpCas9	negative selection	6599473
23034818	23034841	14	+	27260156	HS294T	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.9238583343241511	[124]	[22,19,29,29]	-8	hSpCas9	negative selection	6656463
23026352	23026375	14	+	27260156	HS294T	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.0978686744804658	[608]	[81,121,112,127]	-9	hSpCas9	negative selection	6656464
23034860	23034883	14	-	27260156	HS294T	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.2737676706073734	[388]	[114,169,99,108]	-4	hSpCas9	negative selection	6656465
23026361	23026384	14	-	27260156	HS294T	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.0325571166721426	[239]	[14,26,81,63]	-9	hSpCas9	negative selection	6720722
23033423	23033446	14	+	27260156	HS294T	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.6928744260307462	[344]	[23,27,48,70]	-9	hSpCas9	negative selection	6720723
23033378	23033401	14	+	27260156	HS294T	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.5063956129612541	[1187]	[88,93,208,283]	-9	hSpCas9	negative selection	6720724
23034818	23034841	14	+	27260156	HCC44	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.40219104289153496	[124]	[91,55,173,121]	-6	hSpCas9	negative selection	6777714
23026352	23026375	14	+	27260156	HCC44	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.2517373926463427	[608]	[454,110,431,223]	-9	hSpCas9	negative selection	6777715
23034860	23034883	14	-	27260156	HCC44	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.2725717619837583	[388]	[341,283,510,351]	-4	hSpCas9	negative selection	6777716
23026361	23026384	14	-	27260156	HCC44	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.7529778556122284	[239]	[81,39,145,70]	-9	hSpCas9	negative selection	6841973
23033423	23033446	14	+	27260156	HCC44	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-2.3466344767893768	[344]	[26,63,128,91]	-9	hSpCas9	negative selection	6841974
23033378	23033401	14	+	27260156	HCC44	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-2.0111394185874056	[1187]	[272,381,512,185]	-9	hSpCas9	negative selection	6841975
23034818	23034841	14	+	27260156	G402	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.7488603893656842	[124]	[121,40,18,177]	-7	hSpCas9	negative selection	6898965
23026352	23026375	14	+	27260156	G402	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.8941712597102487	[608]	[235,321,133,122]	-9	hSpCas9	negative selection	6898966
23034860	23034883	14	-	27260156	G402	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.5367392461121445	[388]	[323,285,501,198]	-6	hSpCas9	negative selection	6898967
23026361	23026384	14	-	27260156	G402	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.5778907859113047	[239]	[62,12,80,218]	-9	hSpCas9	negative selection	6963224
23033423	23033446	14	+	27260156	G402	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.5849436339869116	[344]	[167,9,1,365]	-9	hSpCas9	negative selection	6963225
23033378	23033401	14	+	27260156	G402	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.9741635930380665	[1187]	[661,288,254,308]	-9	hSpCas9	negative selection	6963226
23034818	23034841	14	+	27260156	L33	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.10465376071578092	[124]	[124,36,60,151]	-2	hSpCas9	negative selection	7020216
23026352	23026375	14	+	27260156	L33	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.25846849580491593	[608]	[516,216,315,486]	-5	hSpCas9	negative selection	7020217
23034860	23034883	14	-	27260156	L33	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.04148503467215159	[388]	[405,148,288,282]	-1	hSpCas9	negative selection	7020218
23026361	23026384	14	-	27260156	L33	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.0536668339463483	[239]	[189,105,154,301]	1	hSpCas9	negative selection	7084475
23033423	23033446	14	+	27260156	L33	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-0.5938971152366075	[344]	[240,129,93,205]	-8	hSpCas9	negative selection	7084476
23033378	23033401	14	+	27260156	L33	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-0.4404747269216329	[1187]	[850,389,561,805]	-8	hSpCas9	negative selection	7084477
23034818	23034841	14	+	27260156	K562	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-1.0307118775478736	[124]	[64,44,96,14]	-8	hSpCas9	negative selection	7141467
23026352	23026375	14	+	27260156	K562	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-2.115462564825002	[608]	[172,82,174,74]	-9	hSpCas9	negative selection	7141468
23034860	23034883	14	-	27260156	K562	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.5475866696629663	[388]	[254,205,409,89]	-6	hSpCas9	negative selection	7141469
23026361	23026384	14	-	27260156	K562	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-3.5585146479311662	[239]	[11,32,13,13]	-9	hSpCas9	negative selection	7205726
23033423	23033446	14	+	27260156	K562	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-3.4722319560038577	[344]	[71,33,6,3]	-9	hSpCas9	negative selection	7205727
23033378	23033401	14	+	27260156	K562	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-3.368551721678122	[1187]	[172,138,42,64]	-9	hSpCas9	negative selection	7205728
23034818	23034841	14	+	27260156	HT29	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.7956963408371092	[124]	[65,117,29,130]	-8	hSpCas9	negative selection	7262718
23026352	23026375	14	+	27260156	HT29	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-2.073332383192506	[608]	[174,137,209,175]	-9	hSpCas9	negative selection	7262719
23034860	23034883	14	-	27260156	HT29	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.5403517902210616	[388]	[427,399,315,185]	-7	hSpCas9	negative selection	7262720
23026361	23026384	14	-	27260156	HT29	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-2.415205514980232	[239]	[84,27,28,73]	-9	hSpCas9	negative selection	7326977
23033423	23033446	14	+	27260156	HT29	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-2.503183950400137	[344]	[68,159,58,20]	-9	hSpCas9	negative selection	7326978
23033378	23033401	14	+	27260156	HT29	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-2.1315938546519115	[1187]	[400,420,202,306]	-9	hSpCas9	negative selection	7326979
23034818	23034841	14	+	27260156	MHHES1	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.7393744463256775	[124]	[83,130,66,62]	-8	hSpCas9	negative selection	7383969
23026352	23026375	14	+	27260156	MHHES1	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.2536670967232046	[608]	[302,363,299,205]	-9	hSpCas9	negative selection	7383970
23034860	23034883	14	-	27260156	MHHES1	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.2679662502513134	[388]	[441,460,303,278]	-5	hSpCas9	negative selection	7383971
23026361	23026384	14	-	27260156	MHHES1	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.7629521311376224	[239]	[217,65,211,139]	-8	hSpCas9	negative selection	7448228
23033423	23033446	14	+	27260156	MHHES1	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.4666692096691765	[344]	[219,163,63,125]	-9	hSpCas9	negative selection	7448229
23033378	23033401	14	+	27260156	MHHES1	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.1309247207131277	[1187]	[707,740,660,395]	-9	hSpCas9	negative selection	7448230
23034818	23034841	14	+	27260156	MEWO	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-1.1121529926497415	[124]	[52,68,39]	-9	hSpCas9	negative selection	7505220
23026352	23026375	14	+	27260156	MEWO	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.8977541170482894	[608]	[419,194,324]	-9	hSpCas9	negative selection	7505221
23034860	23034883	14	-	27260156	MEWO	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.08100278005453149	[388]	[507,317,237]	-2	hSpCas9	negative selection	7505222
23026361	23026384	14	-	27260156	MEWO	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.981958937652488	[239]	[83,167,82]	-9	hSpCas9	negative selection	7569479
23033423	23033446	14	+	27260156	MEWO	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.4734802783600125	[344]	[101,98,144]	-9	hSpCas9	negative selection	7569480
23033378	23033401	14	+	27260156	MEWO	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.0058886262009135	[1187]	[622,497,552]	-9	hSpCas9	negative selection	7569481
23034818	23034841	14	+	27260156	LNCAPCLONEFGC	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.4103397633666508	[124]	[32,94,43,162]	-6	hSpCas9	negative selection	7626471
23026352	23026375	14	+	27260156	LNCAPCLONEFGC	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.0416595161120437	[608]	[225,263,376,221]	-9	hSpCas9	negative selection	7626472
23034860	23034883	14	-	27260156	LNCAPCLONEFGC	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.4171380448090023	[388]	[270,243,360,194]	-6	hSpCas9	negative selection	7626473
23026361	23026384	14	-	27260156	LNCAPCLONEFGC	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.2903768000903988	[239]	[149,46,74,82]	-9	hSpCas9	negative selection	7690730
23033423	23033446	14	+	27260156	LNCAPCLONEFGC	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.7916208280463681	[344]	[94,87,82,93]	-9	hSpCas9	negative selection	7690731
23033378	23033401	14	+	27260156	LNCAPCLONEFGC	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.5232870105330722	[1187]	[328,385,310,461]	-9	hSpCas9	negative selection	7690732
23034818	23034841	14	+	27260156	PANC0327	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.91201473079999	[124]	[62,21,14,140]	-8	hSpCas9	negative selection	7747722
23026352	23026375	14	+	27260156	PANC0327	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.1528596679469725	[608]	[471,127,326,79]	-9	hSpCas9	negative selection	7747723
23034860	23034883	14	-	27260156	PANC0327	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.06817232846060634	[388]	[192,401,440,261]	-1	hSpCas9	negative selection	7747724
23026361	23026384	14	-	27260156	PANC0327	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-2.459245554983818	[239]	[55,57,32,6]	-9	hSpCas9	negative selection	7811981
23033423	23033446	14	+	27260156	PANC0327	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-2.1053218198002814	[344]	[124,103,26,28]	-9	hSpCas9	negative selection	7811982
23033378	23033401	14	+	27260156	PANC0327	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.0488012227575856	[1187]	[1039,267,462,343]	-8	hSpCas9	negative selection	7811983
23034818	23034841	14	+	27260156	NCIH2009	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.4955860594394159	[124]	[149,99,126]	-6	hSpCas9	negative selection	7868973
23026352	23026375	14	+	27260156	NCIH2009	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.8417715069343701	[608]	[425,463,523]	-7	hSpCas9	negative selection	7868974
23034860	23034883	14	-	27260156	NCIH2009	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.8878856626857203	[388]	[317,261,305]	-8	hSpCas9	negative selection	7868975
23026361	23026384	14	-	27260156	NCIH2009	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-2.8366732644547286	[239]	[47,43,48]	-9	hSpCas9	negative selection	7933232
23033423	23033446	14	+	27260156	NCIH2009	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-2.8814798627622498	[344]	[85,75,37]	-9	hSpCas9	negative selection	7933233
23033378	23033401	14	+	27260156	NCIH2009	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-2.4031080579285398	[1187]	[288,311,334]	-9	hSpCas9	negative selection	7933234
23034818	23034841	14	+	27260156	NCIH1373	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.6552928151107289	[124]	[158,81,91,7]	-6	hSpCas9	negative selection	7990224
23026352	23026375	14	+	27260156	NCIH1373	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.0119895137113637	[608]	[387,309,315,91]	-8	hSpCas9	negative selection	7990225
23034860	23034883	14	-	27260156	NCIH1373	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	0.108509544803809	[388]	[556,442,433,120]	1	hSpCas9	negative selection	7990226
23026361	23026384	14	-	27260156	NCIH1373	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.6624056758499288	[239]	[184,9,38,34]	-9	hSpCas9	negative selection	8054483
23033423	23033446	14	+	27260156	NCIH1373	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.5691519764995607	[344]	[262,172,61,8]	-9	hSpCas9	negative selection	8054484
23033378	23033401	14	+	27260156	NCIH1373	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-2.25183526991069	[1187]	[169,120,356,125]	-9	hSpCas9	negative selection	8054485
23034818	23034841	14	+	27260156	PATU8902	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-1.121178151623476	[124]	[14,147,3,185]	-7	hSpCas9	negative selection	8111475
23026352	23026375	14	+	27260156	PATU8902	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.7944768564526113	[608]	[757,416,285,546]	-6	hSpCas9	negative selection	8111476
23034860	23034883	14	-	27260156	PATU8902	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.06799209303681192	[388]	[607,936,173,421]	0	hSpCas9	negative selection	8111477
23026361	23026384	14	-	27260156	PATU8902	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.159166099892879	[239]	[124,198,64,241]	-8	hSpCas9	negative selection	8175734
23033423	23033446	14	+	27260156	PATU8902	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.711946906557943	[344]	[160,284,34,131]	-8	hSpCas9	negative selection	8175735
23033378	23033401	14	+	27260156	PATU8902	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.228671377546616	[1187]	[864,473,745,721]	-8	hSpCas9	negative selection	8175736
23034818	23034841	14	+	27260156	PANC1	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-1.2796016735708227	[124]	[30,18,86,35]	-9	hSpCas9	negative selection	8232726
23026352	23026375	14	+	27260156	PANC1	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-2.3918706913811016	[608]	[68,178,87,80]	-9	hSpCas9	negative selection	8232727
23034860	23034883	14	-	27260156	PANC1	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-1.020350484127699	[388]	[208,214,110,134]	-8	hSpCas9	negative selection	8232728
23026361	23026384	14	-	27260156	PANC1	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-2.6372291069404525	[239]	[27,24,40,35]	-9	hSpCas9	negative selection	8296985
23033423	23033446	14	+	27260156	PANC1	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-4.7724798312608145	[344]	[8,5,7,17]	-9	hSpCas9	negative selection	8296986
23033378	23033401	14	+	27260156	PANC1	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-2.6530805408446585	[1187]	[109,226,130,187]	-9	hSpCas9	negative selection	8296987
23034818	23034841	14	+	27260156	PANC0813	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.5949635688360857	[124]	[189,71,37,96]	-7	hSpCas9	negative selection	8353977
23026352	23026375	14	+	27260156	PANC0813	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.1493827119116213	[608]	[501,181,384,241]	-9	hSpCas9	negative selection	8353978
23034860	23034883	14	-	27260156	PANC0813	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-1.800612714303311	[388]	[102,115,153,147]	-9	hSpCas9	negative selection	8353979
23026361	23026384	14	-	27260156	PANC0813	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.8698406912600316	[239]	[81,103,50,71]	-9	hSpCas9	negative selection	8418236
23033423	23033446	14	+	27260156	PANC0813	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.8342003643731821	[344]	[158,52,188,60]	-9	hSpCas9	negative selection	8418237
23033378	23033401	14	+	27260156	PANC0813	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.8532908469218463	[1187]	[429,279,389,444]	-9	hSpCas9	negative selection	8418238
23034818	23034841	14	+	27260156	RDES	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.7562960526682723	[124]	[63,73,99,109]	-8	hSpCas9	negative selection	8475228
23026352	23026375	14	+	27260156	RDES	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.3189507223966728	[608]	[257,302,258,297]	-9	hSpCas9	negative selection	8475229
23034860	23034883	14	-	27260156	RDES	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.1755578561642142	[388]	[310,274,455,593]	-3	hSpCas9	negative selection	8475230
23026361	23026384	14	-	27260156	RDES	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.9658131068772529	[239]	[45,87,32,123]	-9	hSpCas9	negative selection	8539487
23033423	23033446	14	+	27260156	RDES	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-2.2979367252262977	[344]	[51,50,92,143]	-9	hSpCas9	negative selection	8539488
23033378	23033401	14	+	27260156	RDES	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.774090587828789	[1187]	[346,420,406,422]	-9	hSpCas9	negative selection	8539489
23034818	23034841	14	+	27260156	PC3	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.8223365310317496	[124]	[20,114,136,48]	-9	hSpCas9	negative selection	8596479
23026352	23026375	14	+	27260156	PC3	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.5107303625692731	[608]	[193,453,833,450]	-8	hSpCas9	negative selection	8596480
23034860	23034883	14	-	27260156	PC3	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	0.20147028340342854	[388]	[288,444,904,342]	4	hSpCas9	negative selection	8596481
23026361	23026384	14	-	27260156	PC3	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.14879786976880005	[239]	[158,344,391,228]	3	hSpCas9	negative selection	8660738
23033423	23033446	14	+	27260156	PC3	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.4885883492590817	[344]	[62,135,193,140]	-9	hSpCas9	negative selection	8660739
23033378	23033401	14	+	27260156	PC3	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-0.7976915323732575	[1187]	[397,492,1346,826]	-9	hSpCas9	negative selection	8660740
23034818	23034841	14	+	27260156	PATU8988T	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-1.5597563728594679	[124]	[27,80,36,19]	-9	hSpCas9	negative selection	8717730
23026352	23026375	14	+	27260156	PATU8988T	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.126783256444167	[608]	[114,329,388,245]	-9	hSpCas9	negative selection	8717731
23034860	23034883	14	-	27260156	PATU8988T	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.3068270496410488	[388]	[250,314,305,347]	-5	hSpCas9	negative selection	8717732
23026361	23026384	14	-	27260156	PATU8988T	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.4627421679047754	[239]	[155,213,97,213]	-6	hSpCas9	negative selection	8781989
23033423	23033446	14	+	27260156	PATU8988T	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.6351117453331623	[344]	[74,24,125,202]	-9	hSpCas9	negative selection	8781990
23033378	23033401	14	+	27260156	PATU8988T	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.752284488974037	[1187]	[391,308,291,369]	-9	hSpCas9	negative selection	8781991
23034818	23034841	14	+	27260156	T47D	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.7695336703127906	[124]	[108,56,74,103]	-9	hSpCas9	negative selection	8838981
23026352	23026375	14	+	27260156	T47D	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.1910270389096558	[608]	[271,270,307,397]	-9	hSpCas9	negative selection	8838982
23034860	23034883	14	-	27260156	T47D	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.07475249889689345	[388]	[423,381,473,444]	-2	hSpCas9	negative selection	8838983
23026361	23026384	14	-	27260156	T47D	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-1.4122729129953437	[239]	[96,89,109,124]	-9	hSpCas9	negative selection	8903240
23033423	23033446	14	+	27260156	T47D	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-2.2126143063766928	[344]	[71,51,96,129]	-9	hSpCas9	negative selection	8903241
23033378	23033401	14	+	27260156	T47D	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.3828137119130004	[1187]	[509,487,541,587]	-9	hSpCas9	negative selection	8903242
23034818	23034841	14	+	27260156	SU8686	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.08501870414697787	[124]	[145,70,145,104]	-1	hSpCas9	negative selection	8960232
23026352	23026375	14	+	27260156	SU8686	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-1.0724857536125925	[608]	[305,274,235,334]	-8	hSpCas9	negative selection	8960233
23034860	23034883	14	-	27260156	SU8686	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.10409885072826391	[388]	[346,303,452,335]	-2	hSpCas9	negative selection	8960234
23026361	23026384	14	-	27260156	SU8686	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.7107738192783055	[239]	[201,159,72,132]	-8	hSpCas9	negative selection	9024491
23033423	23033446	14	+	27260156	SU8686	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.4544712593787736	[344]	[167,108,70,149]	-9	hSpCas9	negative selection	9024492
23033378	23033401	14	+	27260156	SU8686	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.1503499894337705	[1187]	[634,519,386,567]	-9	hSpCas9	negative selection	9024493
23034818	23034841	14	+	27260156	SKES1	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.6812301753883556	[124]	[85,149,27,58]	-9	hSpCas9	negative selection	9081483
23026352	23026375	14	+	27260156	SKES1	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.9365307590692078	[608]	[397,373,228,287]	-9	hSpCas9	negative selection	9081484
23034860	23034883	14	-	27260156	SKES1	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.3826787563537519	[388]	[381,329,263,234]	-7	hSpCas9	negative selection	9081485
23026361	23026384	14	-	27260156	SKES1	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.8146899614759813	[239]	[129,140,75,189]	-9	hSpCas9	negative selection	9145742
23033423	23033446	14	+	27260156	SKES1	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.6018880058553118	[344]	[81,151,97,119]	-9	hSpCas9	negative selection	9145743
23033378	23033401	14	+	27260156	SKES1	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-1.0032317660246748	[1187]	[652,787,466,495]	-9	hSpCas9	negative selection	9145744
23034818	23034841	14	+	27260156	TOV112D	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	0.21695438412224433	[124]	[113,13,99,313]	4	hSpCas9	negative selection	9202734
23026352	23026375	14	+	27260156	TOV112D	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.47021537276648756	[608]	[287,791,488,269]	-7	hSpCas9	negative selection	9202735
23034860	23034883	14	-	27260156	TOV112D	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.27592451197214274	[388]	[182,425,385,305]	-5	hSpCas9	negative selection	9202736
23026361	23026384	14	-	27260156	TOV112D	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.6996701694503917	[239]	[81,223,81,214]	-8	hSpCas9	negative selection	9266993
23033423	23033446	14	+	27260156	TOV112D	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.1770683455010755	[344]	[113,170,166,159]	-9	hSpCas9	negative selection	9266994
23033378	23033401	14	+	27260156	TOV112D	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-0.5740907910554208	[1187]	[488,941,988,784]	-8	hSpCas9	negative selection	9266995
23034818	23034841	14	+	27260156	TC71	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	-0.3442995402745601	[124]	[102,107,87,124]	-7	hSpCas9	negative selection	9323985
23026352	23026375	14	+	27260156	TC71	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.3129518507072157	[608]	[449,542,590,516]	-7	hSpCas9	negative selection	9323986
23034860	23034883	14	-	27260156	TC71	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.13442842110590209	[388]	[364,280,402,475]	-4	hSpCas9	negative selection	9323987
23026361	23026384	14	-	27260156	TC71	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.28927334205215205	[239]	[165,156,245,276]	-7	hSpCas9	negative selection	9388244
23033423	23033446	14	+	27260156	TC71	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-0.777390655514768	[344]	[208,192,206,256]	-9	hSpCas9	negative selection	9388245
23033378	23033401	14	+	27260156	TC71	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-0.43483890767920874	[1187]	[892,881,1046,943]	-8	hSpCas9	negative selection	9388246
23034818	23034841	14	+	27260156	TC32	viability	CAAGTCCGAAAAACCCGCGCTGG	PSMB5	ENSG00000100804	0.09592529903213798	[124]	[117,61,198,155]	1	hSpCas9	negative selection	9445236
23026352	23026375	14	+	27260156	TC32	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.5106353285776315	[608]	[475,282,492,379]	-7	hSpCas9	negative selection	9445237
23034860	23034883	14	-	27260156	TC32	viability	CATGGCGCTTGCCAGCGTGTTGG	PSMB5	ENSG00000100804	-0.3274491131680406	[388]	[292,210,415,278]	-6	hSpCas9	negative selection	9445238
23026361	23026384	14	-	27260156	TC32	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.4800877159716368	[239]	[207,112,166,161]	-7	hSpCas9	negative selection	9509495
23033423	23033446	14	+	27260156	TC32	viability	TTTGTACTGATACACCATGTTGG	PSMB5	ENSG00000100804	-1.5962509075981692	[344]	[94,82,149,112]	-9	hSpCas9	negative selection	9509496
23033378	23033401	14	+	27260156	TC32	viability	CTTATCCCAGCCACAGATCATGG	PSMB5	ENSG00000100804	-0.8613544159734854	[1187]	[500,690,544,654]	-9	hSpCas9	negative selection	9509497
23026357	23026380	14	+	27869803	HPAFII	viability after 27 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-1.5455632366440941	[369]	[118,22,NaN]	-7	hSpCas9	negative selection	9551082
23027749	23027772	14	-	27869803	HPAFII	viability after 27 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.41015328449079225	[827]	[698,477,NaN]	3	hSpCas9	negative selection	9551083
23033349	23033372	14	+	27869803	HPAFII	viability after 27 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-1.7758555162253085	[240]	[42,31,NaN]	-8	hSpCas9	negative selection	9551084
23034641	23034664	14	+	27869803	HPAFII	viability after 27 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	-0.3183697968325419	[405]	[138,197,NaN]	-2	hSpCas9	negative selection	9551085
23034648	23034671	14	+	27869803	HPAFII	viability after 27 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.6529907546471341	[834]	[294,265,NaN]	-5	hSpCas9	negative selection	9551086
23026357	23026380	14	+	27869803	HPAFII	viability after 15 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-1.598065889051502	[369]	[147,120,NaN]	-8	hSpCas9	negative selection	9633531
23027749	23027772	14	-	27869803	HPAFII	viability after 15 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.061417643040186265	[827]	[1218,747,NaN]	0	hSpCas9	negative selection	9633532
23033349	23033372	14	+	27869803	HPAFII	viability after 15 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-0.9684778402882369	[240]	[296,29,NaN]	-7	hSpCas9	negative selection	9633533
23034641	23034664	14	+	27869803	HPAFII	viability after 15 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	-0.24554739200609005	[405]	[380,359,NaN]	-3	hSpCas9	negative selection	9633534
23034648	23034671	14	+	27869803	HPAFII	viability after 15 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.4002157349778812	[834]	[1028,462,NaN]	-4	hSpCas9	negative selection	9633535
23026357	23026380	14	+	27869803	ASPC1	viability after 36 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-0.02821720716990006	[1076]	[692,140,317]	0	hSpCas9	negative selection	9715980
23027749	23027772	14	-	27869803	ASPC1	viability after 36 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.9065883818160114	[1747]	[1046,1819,662]	8	hSpCas9	negative selection	9715981
23033349	23033372	14	+	27869803	ASPC1	viability after 36 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-0.47707998016208	[490]	[102,175,93]	-5	hSpCas9	negative selection	9715982
23034641	23034664	14	+	27869803	ASPC1	viability after 36 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	0.14292911325145163	[1027]	[603,320,305]	1	hSpCas9	negative selection	9715983
23034648	23034671	14	+	27869803	ASPC1	viability after 36 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	0.17941392063693673	[1939]	[1477,597,393]	1	hSpCas9	negative selection	9715984
23026357	23026380	14	+	27869803	PATU8988S	viability after 35 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-1.5219244451210316	[844]	[121,114,NaN]	-8	hSpCas9	negative selection	9798429
23027749	23027772	14	-	27869803	PATU8988S	viability after 35 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.06165664853817754	[1698]	[779,647,NaN]	0	hSpCas9	negative selection	9798430
23033349	23033372	14	+	27869803	PATU8988S	viability after 35 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-2.9135458771006846	[467]	[31,17,NaN]	-9	hSpCas9	negative selection	9798431
23034641	23034664	14	+	27869803	PATU8988S	viability after 35 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	-0.5370833706644285	[774]	[262,166,NaN]	-5	hSpCas9	negative selection	9798432
23034648	23034671	14	+	27869803	PATU8988S	viability after 35 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.4466376407034034	[1962]	[405,754,NaN]	-4	hSpCas9	negative selection	9798433
23026357	23026380	14	+	27869803	PATU8988S	viability after 31 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-1.3551965128171404	[844]	[48,236,NaN]	-8	hSpCas9	negative selection	9880878
23027749	23027772	14	-	27869803	PATU8988S	viability after 31 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.018409903028129504	[1698]	[518,898,NaN]	0	hSpCas9	negative selection	9880879
23033349	23033372	14	+	27869803	PATU8988S	viability after 31 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-2.6939481801972223	[467]	[23,34,NaN]	-9	hSpCas9	negative selection	9880880
23034641	23034664	14	+	27869803	PATU8988S	viability after 31 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	-0.4827504746247896	[774]	[137,326,NaN]	-5	hSpCas9	negative selection	9880881
23034648	23034671	14	+	27869803	PATU8988S	viability after 31 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.25147793961597253	[1962]	[481,880,NaN]	-3	hSpCas9	negative selection	9880882
23026357	23026380	14	+	27869803	HPAFII	viability after 35 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-3.4178934273466397	[369]	[9,25,NaN]	-8	hSpCas9	negative selection	9963327
23027749	23027772	14	-	27869803	HPAFII	viability after 35 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.5752643605655148	[827]	[656,587,NaN]	4	hSpCas9	negative selection	9963328
23033349	23033372	14	+	27869803	HPAFII	viability after 35 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-2.270389080811923	[240]	[13,37,NaN]	-8	hSpCas9	negative selection	9963329
23034641	23034664	14	+	27869803	HPAFII	viability after 35 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	-0.0013770396330249346	[405]	[59,368,NaN]	0	hSpCas9	negative selection	9963330
23034648	23034671	14	+	27869803	HPAFII	viability after 35 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.9723041092164152	[834]	[182,251,NaN]	-5	hSpCas9	negative selection	9963331
23026357	23026380	14	+	27869803	HPAFII	viability after 31 days	CTGTCCACGTAGTAGAGGCCTGG	PSMB5	ENSG00000100804	-2.6826350349541386	[369]	[39,23,NaN]	-8	hSpCas9	negative selection	10045776
23027749	23027772	14	-	27869803	HPAFII	viability after 31 days	TGCTGAGAGGATCGGCAACATGG	PSMB5	ENSG00000100804	0.23471598250547854	[827]	[675,405,NaN]	1	hSpCas9	negative selection	10045777
23033349	23033372	14	+	27869803	HPAFII	viability after 31 days	TGGTTGCAGCTTAACTCACCAGG	PSMB5	ENSG00000100804	-2.566749460571694	[240]	[18,26,NaN]	-8	hSpCas9	negative selection	10045778
23034641	23034664	14	+	27869803	HPAFII	viability after 31 days	CGGGCGTTCAGTACTCAGCCTGG	PSMB5	ENSG00000100804	-0.7216492052057616	[405]	[74,206,NaN]	-5	hSpCas9	negative selection	10045779
23034648	23034671	14	+	27869803	HPAFII	viability after 31 days	TCAGTACTCAGCCTGGCAAGGGG	PSMB5	ENSG00000100804	-0.5100668590630177	[834]	[307,351,NaN]	-3	hSpCas9	negative selection	10045780
23033416	23033439	14	-	28162770	P31FUJ	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	0.34581876943295087	[303]	[453]	4	hSpCas9	negative selection	10218820
23034769	23034792	14	-	28162770	P31FUJ	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-0.6677972158195442	[460]	[340]	-5	hSpCas9	negative selection	10218821
23033388	23033411	14	-	28162770	P31FUJ	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-0.09181210369174653	[262]	[289]	-1	hSpCas9	negative selection	10218822
23033438	23033461	14	+	28162770	P31FUJ	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	0.742859345143023	[268]	[528]	8	hSpCas9	negative selection	10218823
23033373	23033396	14	-	28162770	P31FUJ	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	0.049173765072875325	[226]	[275]	0	hSpCas9	negative selection	10218824
23033404	23033427	14	-	28162770	P31FUJ	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	0.80088092184191	[253]	[519]	8	hSpCas9	negative selection	10218825
23026352	23026375	14	+	28162770	P31FUJ	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	0.10902544791068824	[863]	[1094]	1	hSpCas9	negative selection	10218826
23026361	23026384	14	-	28162770	P31FUJ	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.25707580358162074	[1201]	[1687]	2	hSpCas9	negative selection	10218827
23033416	23033439	14	-	28162770	TF1	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10388186
23034769	23034792	14	-	28162770	TF1	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10388187
23033388	23033411	14	-	28162770	TF1	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10388188
23033438	23033461	14	+	28162770	TF1	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10388189
23033373	23033396	14	-	28162770	TF1	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10388190
23033404	23033427	14	-	28162770	TF1	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	NaN	[NaN]	[12]	1	hSpCas9	negative selection	10388191
23026352	23026375	14	+	28162770	TF1	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	NaN	[NaN]	[156]	1	hSpCas9	negative selection	10388192
23026361	23026384	14	-	28162770	TF1	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	NaN	[NaN]	[198]	1	hSpCas9	negative selection	10388193
23033416	23033439	14	-	28162770	SKM1	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-0.6625234840148089	[76]	[85]	-5	hSpCas9	negative selection	10557552
23034769	23034792	14	-	28162770	SKM1	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	0.633192927728821	[61]	[169]	6	hSpCas9	negative selection	10557553
23033388	23033411	14	-	28162770	SKM1	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	0.4880196301811826	[72]	[180]	5	hSpCas9	negative selection	10557554
23033438	23033461	14	+	28162770	SKM1	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	0.01852008797079785	[85]	[153]	0	hSpCas9	negative selection	10557555
23033373	23033396	14	-	28162770	SKM1	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-0.6273542671684619	[89]	[102]	-5	hSpCas9	negative selection	10557556
23033404	23033427	14	-	28162770	SKM1	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	-0.14392979290936778	[59]	[95]	-1	hSpCas9	negative selection	10557557
23026352	23026375	14	+	28162770	SKM1	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	0.36086235912780507	[221]	[503]	3	hSpCas9	negative selection	10557558
23026361	23026384	14	-	28162770	SKM1	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.2877618682035368	[252]	[545]	3	hSpCas9	negative selection	10557559
23033416	23033439	14	-	28162770	SKM1	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-0.6625234840148089	[76]	[85]	-5	hSpCas9	negative selection	10726918
23034769	23034792	14	-	28162770	SKM1	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	0.633192927728821	[61]	[169]	6	hSpCas9	negative selection	10726919
23033388	23033411	14	-	28162770	SKM1	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	0.4880196301811826	[72]	[180]	5	hSpCas9	negative selection	10726920
23033438	23033461	14	+	28162770	SKM1	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	0.01852008797079785	[85]	[153]	0	hSpCas9	negative selection	10726921
23033373	23033396	14	-	28162770	SKM1	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-0.6273542671684619	[89]	[102]	-5	hSpCas9	negative selection	10726922
23033404	23033427	14	-	28162770	SKM1	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	-0.14392979290936778	[59]	[95]	-1	hSpCas9	negative selection	10726923
23026352	23026375	14	+	28162770	SKM1	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	0.36086235912780507	[221]	[503]	3	hSpCas9	negative selection	10726924
23026361	23026384	14	-	28162770	SKM1	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.2877618682035368	[252]	[545]	3	hSpCas9	negative selection	10726925
23033416	23033439	14	-	28162770	PL21	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-1.2248819733621459	[289]	[53]	-7	hSpCas9	negative selection	10896284
23034769	23034792	14	-	28162770	PL21	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-0.8039531401445629	[352]	[87]	-5	hSpCas9	negative selection	10896285
23033388	23033411	14	-	28162770	PL21	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	0.1894132078962617	[269]	[133]	1	hSpCas9	negative selection	10896286
23033438	23033461	14	+	28162770	PL21	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	0.18157185445004798	[390]	[192]	1	hSpCas9	negative selection	10896287
23033373	23033396	14	-	28162770	PL21	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	1.2170134330537163	[254]	[257]	8	hSpCas9	negative selection	10896288
23033404	23033427	14	-	28162770	PL21	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	0.6401811198980584	[142]	[96]	5	hSpCas9	negative selection	10896289
23026352	23026375	14	+	28162770	PL21	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	0.5629629093272257	[632]	[406]	5	hSpCas9	negative selection	10896290
23026361	23026384	14	-	28162770	PL21	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.4870207622774818	[799]	[487]	4	hSpCas9	negative selection	10896291
23033416	23033439	14	-	28162770	P31FUJ	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	0.34581876943295087	[303]	[453]	4	hSpCas9	negative selection	11065650
23034769	23034792	14	-	28162770	P31FUJ	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-0.6677972158195442	[460]	[340]	-5	hSpCas9	negative selection	11065651
23033388	23033411	14	-	28162770	P31FUJ	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-0.09181210369174653	[262]	[289]	-1	hSpCas9	negative selection	11065652
23033438	23033461	14	+	28162770	P31FUJ	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	0.742859345143023	[268]	[528]	8	hSpCas9	negative selection	11065653
23033373	23033396	14	-	28162770	P31FUJ	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	0.049173765072875325	[226]	[275]	0	hSpCas9	negative selection	11065654
23033404	23033427	14	-	28162770	P31FUJ	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	0.80088092184191	[253]	[519]	8	hSpCas9	negative selection	11065655
23026352	23026375	14	+	28162770	P31FUJ	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	0.10902544791068824	[863]	[1094]	1	hSpCas9	negative selection	11065656
23026361	23026384	14	-	28162770	P31FUJ	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.25707580358162074	[1201]	[1687]	2	hSpCas9	negative selection	11065657
23033416	23033439	14	-	28162770	OCIAML5	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	0.12416526320305316	[152]	[300]	1	hSpCas9	negative selection	11235016
23034769	23034792	14	-	28162770	OCIAML5	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-0.1331348995280524	[160]	[264]	-1	hSpCas9	negative selection	11235017
23033388	23033411	14	-	28162770	OCIAML5	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-0.5590898496727637	[150]	[184]	-4	hSpCas9	negative selection	11235018
23033438	23033461	14	+	28162770	OCIAML5	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	1.0686701506113496	[158]	[601]	8	hSpCas9	negative selection	11235019
23033373	23033396	14	-	28162770	OCIAML5	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	1.27474819049022	[116]	[510]	9	hSpCas9	negative selection	11235020
23033404	23033427	14	-	28162770	OCIAML5	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	0.33235800027343054	[120]	[274]	3	hSpCas9	negative selection	11235021
23026352	23026375	14	+	28162770	OCIAML5	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.07597735232048208	[712]	[1220]	0	hSpCas9	negative selection	11235022
23026361	23026384	14	-	28162770	OCIAML5	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.660358846153001	[604]	[1725]	6	hSpCas9	negative selection	11235023
23033416	23033439	14	-	28162770	EOL1	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	0.48989551163341905	[468]	[346]	4	hSpCas9	negative selection	11404382
23034769	23034792	14	-	28162770	EOL1	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-1.551185659395863	[444]	[79]	-7	hSpCas9	negative selection	11404383
23033388	23033411	14	-	28162770	EOL1	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-1.8633547878208971	[441]	[63]	-8	hSpCas9	negative selection	11404384
23033438	23033461	14	+	28162770	EOL1	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	-1.0956301103670958	[575]	[141]	-6	hSpCas9	negative selection	11404385
23033373	23033396	14	-	28162770	EOL1	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	0.5072507651095659	[425]	[318]	4	hSpCas9	negative selection	11404386
23033404	23033427	14	-	28162770	EOL1	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	-1.2118246701607513	[254]	[57]	-7	hSpCas9	negative selection	11404387
23026352	23026375	14	+	28162770	EOL1	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	0.16520647974082237	[952]	[562]	1	hSpCas9	negative selection	11404388
23026361	23026384	14	-	28162770	EOL1	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.08116587962385924	[1011]	[503]	0	hSpCas9	negative selection	11404389
23033416	23033439	14	-	28162770	MOLM13	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-1.3394655405130254	[419]	[119]	-6	hSpCas9	negative selection	11573748
23034769	23034792	14	-	28162770	MOLM13	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-2.284800564914644	[491]	[72]	-8	hSpCas9	negative selection	11573749
23033388	23033411	14	-	28162770	MOLM13	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-1.0460723502754383	[336]	[117]	-5	hSpCas9	negative selection	11573750
23033438	23033461	14	+	28162770	MOLM13	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	-1.2560833741766668	[478]	[144]	-6	hSpCas9	negative selection	11573751
23033373	23033396	14	-	28162770	MOLM13	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-0.7197376216311925	[368]	[161]	-4	hSpCas9	negative selection	11573752
23033404	23033427	14	-	28162770	MOLM13	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	-2.1585497551527366	[246]	[39]	-7	hSpCas9	negative selection	11573753
23026352	23026375	14	+	28162770	MOLM13	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.6795779501197943	[987]	[445]	-4	hSpCas9	negative selection	11573754
23026361	23026384	14	-	28162770	MOLM13	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.9471481177342651	[1023]	[383]	-5	hSpCas9	negative selection	11573755
23033416	23033439	14	-	28162770	HEL	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-5.342154275609435	[379]	[5]	-9	hSpCas9	negative selection	11743114
23034769	23034792	14	-	28162770	HEL	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-2.6476536894538985	[361]	[36]	-8	hSpCas9	negative selection	11743115
23033388	23033411	14	-	28162770	HEL	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-4.527186169441955	[287]	[7]	-9	hSpCas9	negative selection	11743116
23033438	23033461	14	+	28162770	HEL	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	-1.2394897093738924	[434]	[117]	-6	hSpCas9	negative selection	11743117
23033373	23033396	14	-	28162770	HEL	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-2.5860798584955242	[374]	[39]	-8	hSpCas9	negative selection	11743118
23033404	23033427	14	-	28162770	HEL	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	-4.566714533628593	[221]	[5]	-9	hSpCas9	negative selection	11743119
23026352	23026375	14	+	28162770	HEL	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-2.0516896481068736	[957]	[147]	-8	hSpCas9	negative selection	11743120
23026361	23026384	14	-	28162770	HEL	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-3.26104585274034	[927]	[61]	-9	hSpCas9	negative selection	11743121
23033416	23033439	14	-	28162770	MV411	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-1.6251015400349662	[248]	[67]	-7	hSpCas9	negative selection	11912480
23034769	23034792	14	-	28162770	MV411	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-1.905641779221614	[297]	[66]	-8	hSpCas9	negative selection	11912481
23033388	23033411	14	-	28162770	MV411	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-2.3164633344105514	[271]	[45]	-8	hSpCas9	negative selection	11912482
23033438	23033461	14	+	28162770	MV411	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	-1.4487817010401218	[255]	[78]	-7	hSpCas9	negative selection	11912483
23033373	23033396	14	-	28162770	MV411	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-1.8427602581888025	[263]	[61]	-8	hSpCas9	negative selection	11912484
23033404	23033427	14	-	28162770	MV411	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	-0.32113051168771234	[174]	[117]	-2	hSpCas9	negative selection	11912485
23026352	23026375	14	+	28162770	MV411	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.6349108605629517	[611]	[331]	-4	hSpCas9	negative selection	11912486
23026361	23026384	14	-	28162770	MV411	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	-0.47796451141676743	[786]	[475]	-4	hSpCas9	negative selection	11912487
23033416	23033439	14	-	28162770	MONOMAC1	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-0.08456211780114115	[147]	[159]	0	hSpCas9	negative selection	12081846
23034769	23034792	14	-	28162770	MONOMAC1	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-0.03306111194842776	[215]	[241]	0	hSpCas9	negative selection	12081847
23033388	23033411	14	-	28162770	MONOMAC1	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-0.3275388712936815	[184]	[168]	-3	hSpCas9	negative selection	12081848
23033438	23033461	14	+	28162770	MONOMAC1	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	0.34128492854281345	[240]	[349]	3	hSpCas9	negative selection	12081849
23033373	23033396	14	-	28162770	MONOMAC1	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	0.07967249567131651	[174]	[211]	0	hSpCas9	negative selection	12081850
23033404	23033427	14	-	28162770	MONOMAC1	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	0.05027320648122359	[122]	[145]	0	hSpCas9	negative selection	12081851
23026352	23026375	14	+	28162770	MONOMAC1	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	-0.04010386583656089	[408]	[455]	0	hSpCas9	negative selection	12081852
23026361	23026384	14	-	28162770	MONOMAC1	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.19922344518866186	[521]	[686]	2	hSpCas9	negative selection	12081853
23033416	23033439	14	-	28162770	OCIAML2	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-0.6281711022286413	[57]	[207]	-5	hSpCas9	negative selection	12251212
23034769	23034792	14	-	28162770	OCIAML2	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-1.6747705420223862	[71]	[124]	-7	hSpCas9	negative selection	12251213
23033388	23033411	14	-	28162770	OCIAML2	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-0.3288558641139978	[45]	[202]	-3	hSpCas9	negative selection	12251214
23033438	23033461	14	+	28162770	OCIAML2	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	0.05293213081485171	[55]	[321]	0	hSpCas9	negative selection	12251215
23033373	23033396	14	-	28162770	OCIAML2	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-0.03233697366301441	[49]	[270]	0	hSpCas9	negative selection	12251216
23033404	23033427	14	-	28162770	OCIAML2	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	-0.2689959640725106	[29]	[137]	-2	hSpCas9	negative selection	12251217
23026352	23026375	14	+	28162770	OCIAML2	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	0.32064535714758136	[115]	[802]	3	hSpCas9	negative selection	12251218
23026361	23026384	14	-	28162770	OCIAML2	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.10505486189098412	[129]	[774]	1	hSpCas9	negative selection	12251219
23033416	23033439	14	-	28162770	OCIAML3	viability	GGTGTATCAGTACAAAGGCATGG	PSMB5	ENSG00000100804	-0.9845920958784679	[77]	[118]	-6	hSpCas9	negative selection	12420578
23034769	23034792	14	-	28162770	OCIAML3	viability	GGTCCAGGGAGTCTCAGTGATGG	PSMB5	ENSG00000100804	-0.9437536793512877	[71]	[112]	-6	hSpCas9	negative selection	12420579
23033388	23033411	14	-	28162770	OCIAML3	viability	TCCATGGGCACCATGATCTGTGG	PSMB5	ENSG00000100804	-0.813320668728639	[77]	[133]	-6	hSpCas9	negative selection	12420580
23033438	23033461	14	+	28162770	OCIAML3	viability	CATGTTGGCAAGCAGTTTGGAGG	PSMB5	ENSG00000100804	0.38891884631689544	[84]	[335]	3	hSpCas9	negative selection	12420581
23033373	23033396	14	-	28162770	OCIAML3	viability	ATCTGTGGCTGGGATAAGAGAGG	PSMB5	ENSG00000100804	-0.43354296813091714	[84]	[189]	-3	hSpCas9	negative selection	12420582
23033404	23033427	14	-	28162770	OCIAML3	viability	CAAAGGCATGGGGCTGTCCATGG	PSMB5	ENSG00000100804	-0.8141334546886662	[52]	[90]	-6	hSpCas9	negative selection	12420583
23026352	23026375	14	+	28162770	OCIAML3	viability	CTTCACTGTCCACGTAGTAGAGG	PSMB5	ENSG00000100804	0.42202246949478583	[178]	[723]	4	hSpCas9	negative selection	12420584
23026361	23026384	14	-	28162770	OCIAML3	viability	CTTTCCAGGCCTCTACTACGTGG	PSMB5	ENSG00000100804	0.12087545576376968	[236]	[777]	1	hSpCas9	negative selection	12420585