Gene2Function

Crispr

Gene Info

Species: Human (Homo sapiens)
GeneID: 5700
Symbol: PSMC1
Description: proteasome 26S subunit, ATPase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PSMC1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
90263658	90263681	14	+	26472758	Jiyoye	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-6.116386574551139	[91]	[0]	-9	hSpCas9	negative selection	129903
90264088	90264111	14	+	26472758	Jiyoye	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	-1.1777871192152827	[137]	[45]	-7	hSpCas9	negative selection	129904
90260190	90260213	14	+	26472758	Jiyoye	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	1.0661384636708064	[132]	[209]	7	hSpCas9	negative selection	129905
90259157	90259180	14	+	26472758	Jiyoye	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-2.030746008446309	[232]	[42]	-8	hSpCas9	negative selection	129907
90265154	90265177	14	-	26472758	Jiyoye	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	0.9477437628685759	[10]	[15]	6	hSpCas9	negative selection	129908
90264037	90264060	14	+	26472758	Jiyoye	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-3.442929188011068	[821]	[56]	-9	hSpCas9	negative selection	129909
90264118	90264141	14	+	26472758	Jiyoye	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-3.3199199686362713	[436]	[32]	-9	hSpCas9	negative selection	129911
90263658	90263681	14	+	26472758	KBM7	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-3.34271671196896	[285,121]	[6,10]	-9	hSpCas9	negative selection	321021
90264088	90264111	14	+	26472758	KBM7	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	0.1479320963448012	[145,277]	[123,105]	1	hSpCas9	negative selection	321022
90260190	90260213	14	+	26472758	KBM7	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.4267905072915663	[1040,662]	[492,560]	4	hSpCas9	negative selection	321023
90259157	90259180	14	+	26472758	KBM7	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-2.1387667366425336	[861,742]	[76,92]	-8	hSpCas9	negative selection	321025
90265154	90265177	14	-	26472758	KBM7	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	0.3289257254326807	[144,99]	[130,17]	3	hSpCas9	negative selection	321026
90264037	90264060	14	+	26472758	KBM7	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-1.8243258037354995	[2551,3025]	[444,312]	-8	hSpCas9	negative selection	321027
90264118	90264141	14	+	26472758	KBM7	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-1.152260884197068	[1179,946]	[231,215]	-7	hSpCas9	negative selection	321029
90263658	90263681	14	+	26472758	Raji	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-3.416178420683414	[91]	[1]	-9	hSpCas9	negative selection	512139
90264088	90264111	14	+	26472758	Raji	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	-0.016944599628602175	[108]	[24]	0	hSpCas9	negative selection	512140
90260190	90260213	14	+	26472758	Raji	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.10821332445399529	[352]	[75]	-1	hSpCas9	negative selection	512141
90259157	90259180	14	+	26472758	Raji	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-1.5512360070728657	[441]	[34]	-8	hSpCas9	negative selection	512143
90265154	90265177	14	-	26472758	Raji	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-0.4775789653475564	[65]	[10]	-4	hSpCas9	negative selection	512144
90264037	90264060	14	+	26472758	Raji	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-2.8348813903368044	[1444]	[46]	-9	hSpCas9	negative selection	512145
90264118	90264141	14	+	26472758	Raji	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-1.6111353045808288	[802]	[60]	-8	hSpCas9	negative selection	512147
90263658	90263681	14	+	26472758	K562	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-1.5045195081658351	[120]	[35]	-6	hSpCas9	negative selection	703257
90264088	90264111	14	+	26472758	K562	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	0.36769010256818074	[212]	[231]	3	hSpCas9	negative selection	703258
90260190	90260213	14	+	26472758	K562	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.20328003287296031	[497]	[483]	1	hSpCas9	negative selection	703259
90259157	90259180	14	+	26472758	K562	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-3.3194821575268794	[815]	[68]	-8	hSpCas9	negative selection	703261
90265154	90265177	14	-	26472758	K562	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-3.9594536056992027	[128]	[6]	-9	hSpCas9	negative selection	703262
90264037	90264060	14	+	26472758	K562	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-3.213900987223411	[2593]	[235]	-8	hSpCas9	negative selection	703263
90264118	90264141	14	+	26472758	K562	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-2.7819964590483646	[936]	[114]	-8	hSpCas9	negative selection	703265
90263832	90263855	14	-	26627737	DLD1	viability	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	0.2375301570439955	[249]	[69,42,151]	2	hSpCas9	negative selection	789687
90263832	90263855	14	-	26627737	GBM cells	viability after 5 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	-0.38171459096284654	[197]	[59,102]	-5	hSpCas9	negative selection	872002
90263832	90263855	14	-	26627737	GBM cells	viability after 13 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	-0.2450651912367161	[197]	[72,104]	-3	hSpCas9	negative selection	954317
90263832	90263855	14	-	26627737	GBM cells	viability after 21 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	0.14704086855150908	[197]	[139,99]	1	hSpCas9	negative selection	1036632
90263832	90263855	14	-	26627737	RPE1	viability after 9 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	-2.3401114187279974	[930]	[26,96]	-9	hSpCas9	negative selection	1118947
90263832	90263855	14	-	26627737	RPE1	viability after 12 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	-2.9511507199987403	[930]	[9,55]	-9	hSpCas9	negative selection	1201262
90263832	90263855	14	-	26627737	RPE1	viability after 15 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	-2.0969417069412897	[930]	[29,91]	-8	hSpCas9	negative selection	1283577
90263832	90263855	14	-	26627737	RPE1	viability after 18 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	-3.243114821452244	[930]	[12,40]	-9	hSpCas9	negative selection	1365892
90263832	90263855	14	-	26627737	HeLa	viability after 8 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	-0.3658258899274265	[125]	[43,41,41]	-4	hSpCas9	negative selection	1448207
90263832	90263855	14	-	26627737	HeLa	viability after 12 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	0.9326974445072959	[125]	[126,70,103]	7	hSpCas9	negative selection	1530522
90263832	90263855	14	-	26627737	HeLa	viability after 15 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	0.7799872850464268	[125]	[44,92,129]	6	hSpCas9	negative selection	1612837
90263832	90263855	14	-	26627737	HeLa	viability after 18 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	0.8361516129760923	[125]	[36,76,129]	6	hSpCas9	negative selection	1695152
90263832	90263855	14	-	26627737	HCT116	viability after 6 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	0.7377922413269551	[350]	[111,80]	4	hSpCas9	negative selection	1777467
90263832	90263855	14	-	26627737	HCT116	viability after 8 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	0.9295901237087711	[92]	[65,106,118]	8	hSpCas9	negative selection	1859782
90263832	90263855	14	-	26627737	HCT116	viability after 9 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	1.3174143865862666	[350]	[270,203]	8	hSpCas9	negative selection	1942097
90263832	90263855	14	-	26627737	HCT116	viability after 12 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	0.9361485276842484	[92]	[112,58,105]	7	hSpCas9	negative selection	2024412
90263832	90263855	14	-	26627737	HCT116	viability after 15 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	0.8291573059635976	[92]	[87,114,80]	7	hSpCas9	negative selection	2106727
90263832	90263855	14	-	26627737	HCT116	viability after 18 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	0.46868898475395815	[92]	[49,89,43]	4	hSpCas9	negative selection	2189042
90264080	90264103	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCTTCATCACTGTGACCAGGGG	PSMC1	ENSG00000100764	-0.8727466754244355	[1,1]	[0,0]	-8	hSpCas9	positive selection	3014338
90264121	90264144	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGACCTATGCAGATATTGGGGGG	PSMC1	ENSG00000100764	-0.41484897560656875	[2,3]	[0,1]	-5	hSpCas9	positive selection	3014339
90260205	90260228	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAAGCCATGTCATTACCCAGTGG	PSMC1	ENSG00000100764	0.19666074889297402	[1,2]	[2,1]	4	hSpCas9	positive selection	3014340
90260191	90260214	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.34404547858426143	[4,3]	[2,5]	7	hSpCas9	positive selection	3014341
90264080	90264103	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCTTCATCACTGTGACCAGGGG	PSMC1	ENSG00000100764	-0.973590307878693	[1,1]	[0,0]	-9	hSpCas9	positive selection	3082196
90264121	90264144	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGACCTATGCAGATATTGGGGGG	PSMC1	ENSG00000100764	-0.13461835992252918	[2,2]	[1,1]	-2	hSpCas9	positive selection	3082197
90260205	90260228	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAAGCCATGTCATTACCCAGTGG	PSMC1	ENSG00000100764	-0.08780381664392489	[1,1]	[2,0]	-1	hSpCas9	positive selection	3082198
90260191	90260214	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.08766643914606909	[4,4]	[2,2]	1	hSpCas9	positive selection	3082199
90263318	90263341	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGACACCTCACACTCAGTGCCGG	PSMC1	ENSG00000100764	-0.2264895658184215	[178,178]	[0,0]	-1	hSpCas9	positive selection	3387988
90263364	90263387	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	0.8650087886670746	[83,83]	[0,0]	4	hSpCas9	positive selection	3387989
90265096	90265119	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCTGAATATTATGAAGAGATGG	PSMC1	ENSG00000100764	-0.3647256080105413	[196,196]	[0,0]	-2	hSpCas9	positive selection	3387990
90264080	90264103	14	-	26780180	HT29	viability (Avana library 4 designs)	ACCTTCATCACTGTGACCAGGGG	PSMC1	ENSG00000100764	5.08700322719696	[]	[]	9	hSpCas9	negative selection	3452570
90264120	90264143	14	+	26780180	HT29	viability (Avana library 4 designs)	AGACCTATGCAGATATTGGGGGG	PSMC1	ENSG00000100764	6.35158341993041	[]	[]	9	hSpCas9	negative selection	3452571
90260205	90260228	14	-	26780180	HT29	viability (Avana library 4 designs)	GAAGCCATGTCATTACCCAGTGG	PSMC1	ENSG00000100764	4.91155615577234	[]	[]	9	hSpCas9	negative selection	3452572
90260190	90260213	14	+	26780180	HT29	viability (Avana library 4 designs)	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	1.58799484931792	[]	[]	6	hSpCas9	negative selection	3452573
90264120	90264143	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGACCTATGCAGATATTGGGGGG	PSMC1	ENSG00000100764	-11.3655135286656	[]	[]	-8	hSpCas9	negative selection	3549009
90260205	90260228	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAAGCCATGTCATTACCCAGTGG	PSMC1	ENSG00000100764	-15.8298983225983	[]	[]	-9	hSpCas9	negative selection	3549010
90260190	90260213	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	3.03542993404373	[]	[]	4	hSpCas9	negative selection	3549011
90264080	90264103	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCTTCATCACTGTGACCAGGGG	PSMC1	ENSG00000100764	-14.8814778555571	[]	[]	-9	hSpCas9	negative selection	3549012
90263658	90263681	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-18.5192428692013	[]	[]	-9	hSpCas9	negative selection	3549013
90263671	90263694	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAAAAGTGGATGATCTGAGGGG	PSMC1	ENSG00000100764	-19.0100223998959	[]	[]	-9	hSpCas9	negative selection	3549014
90264120	90264143	14	+	26780180	A375	viability (Avana lentiGuide)	AGACCTATGCAGATATTGGGGGG	PSMC1	ENSG00000100764	28.5751633457809	[]	[]	9	hSpCas9	negative selection	3657668
90260205	90260228	14	-	26780180	A375	viability (Avana lentiGuide)	GAAGCCATGTCATTACCCAGTGG	PSMC1	ENSG00000100764	29.0137605318086	[]	[]	9	hSpCas9	negative selection	3657669
90260190	90260213	14	+	26780180	A375	viability (Avana lentiGuide)	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	2.60427014353215	[]	[]	2	hSpCas9	negative selection	3657670
90264080	90264103	14	-	26780180	A375	viability (Avana lentiGuide)	ACCTTCATCACTGTGACCAGGGG	PSMC1	ENSG00000100764	25.1908352676256	[]	[]	9	hSpCas9	negative selection	3657671
90263658	90263681	14	+	26780180	A375	viability (Avana lentiGuide)	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	20.1849135230633	[]	[]	8	hSpCas9	negative selection	3657672
90263671	90263694	14	+	26780180	A375	viability (Avana lentiGuide)	TCAAAAGTGGATGATCTGAGGGG	PSMC1	ENSG00000100764	22.7716804042515	[]	[]	9	hSpCas9	negative selection	3657673
90264120	90264143	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGACCTATGCAGATATTGGGGGG	PSMC1	ENSG00000100764	-0.7807437297238146	[6]	[3,3]	-8	hSpCas9	positive selection	3766275
90260205	90260228	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAGCCATGTCATTACCCAGTGG	PSMC1	ENSG00000100764	-1.2965384690603847	[4]	[1,1]	-9	hSpCas9	positive selection	3766276
90260190	90260213	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.16650308004816278	[4]	[5,5]	4	hSpCas9	positive selection	3766277
90264080	90264103	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCTTCATCACTGTGACCAGGGG	PSMC1	ENSG00000100764	-1.5140743674016086	[5]	[0,1]	-9	hSpCas9	positive selection	3766278
90263658	90263681	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-1.8734605309635972	[6]	[1,0]	-9	hSpCas9	positive selection	3766279
90263671	90263694	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAAAAGTGGATGATCTGAGGGG	PSMC1	ENSG00000100764	-1.226651906198923	[5]	[1,2]	-9	hSpCas9	positive selection	3766280
90264120	90264143	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGACCTATGCAGATATTGGGGGG	PSMC1	ENSG00000100764	-0.6704256193678222	[6]	[1,4]	-7	hSpCas9	positive selection	3874882
90260205	90260228	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAGCCATGTCATTACCCAGTGG	PSMC1	ENSG00000100764	-2.4534002829532526	[5]	[0,0]	-9	hSpCas9	positive selection	3874883
90260190	90260213	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.3325051072836726	[6]	[2,4]	-4	hSpCas9	positive selection	3874884
90264080	90264103	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCTTCATCACTGTGACCAGGGG	PSMC1	ENSG00000100764	-0.8332426269571467	[4]	[2,1]	-8	hSpCas9	positive selection	3874885
90263658	90263681	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-1.18267338809282	[5]	[0,1]	-9	hSpCas9	positive selection	3874886
90263671	90263694	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAAAAGTGGATGATCTGAGGGG	PSMC1	ENSG00000100764	-1.2559181897256007	[5]	[1,0]	-9	hSpCas9	positive selection	3874887
90263364	90263387	14	+	26780180	A375	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	2.06615869172582	[]	[]	9	hSpCas9	negative selection	3985321
90265154	90265177	14	-	26780180	A375	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	1.41949942445471	[]	[]	7	hSpCas9	negative selection	3985322
90259154	90259177	14	+	26780180	A375	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	0.433712220537465	[]	[]	1	hSpCas9	negative selection	3985323
90263364	90263387	14	+	26780180	HT29	viability (GeCKOv2 library)	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	2.55106590436161	[]	[]	9	hSpCas9	negative selection	4093287
90265154	90265177	14	-	26780180	HT29	viability (GeCKOv2 library)	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	2.18171831870926	[]	[]	9	hSpCas9	negative selection	4093288
90259154	90259177	14	+	26780180	HT29	viability (GeCKOv2 library)	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	0.616711617679404	[]	[]	2	hSpCas9	negative selection	4093289
90265154	90265177	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-0.8994810383504283	[2]	[0,0]	-9	hSpCas9	positive selection	4292759
90259154	90259177	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.2913520975671302	[0]	[0,0]	-6	hSpCas9	positive selection	4292760
90263364	90263387	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.8471723424654253	[3]	[2,0]	-9	hSpCas9	positive selection	4357019
90260191	90260213	14	+	27760321	OCIAML3	viability	CTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.12653705075505806	[569,518]	[388,390]	-1	hSpCas9	negative selection	4431423
90264038	90264060	14	+	27760321	OCIAML3	viability	TAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	0.003415337610507746	[400,397]	[304,325]	0	hSpCas9	negative selection	4431424
90260191	90260213	14	+	27760321	OCIAML2	viability	CTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.013907803741925184	[569,518]	[371,539]	0	hSpCas9	negative selection	4514886
90264038	90264060	14	+	27760321	OCIAML2	viability	TAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-1.5748280713086036	[400,397]	[94,126]	-8	hSpCas9	negative selection	4514887
90260191	90260213	14	+	27760321	MV411	viability	CTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.673902284403739	[569,518]	[723,345]	5	hSpCas9	negative selection	4598349
90264038	90264060	14	+	27760321	MV411	viability	TAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-1.1446823697671655	[400,397]	[109,133]	-6	hSpCas9	negative selection	4598350
90260191	90260213	14	+	27760321	HL60	viability	CTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-1.1168973345005473	[569,518]	[203,205]	-8	hSpCas9	negative selection	4681812
90264038	90264060	14	+	27760321	HL60	viability	TAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-2.280803054441184	[400,397]	[45,89]	-9	hSpCas9	negative selection	4681813
90260191	90260213	14	+	27760321	HT1080	viability	CTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.6682362001925664	[518,404]	[132,96]	-3	hSpCas9	negative selection	4765275
90264038	90264060	14	+	27760321	HT1080	viability	TAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-7.141932651056538	[397,310]	[0,0]	-9	hSpCas9	negative selection	4765276
90260191	90260213	14	+	27760321	HT29	viability after 7 days	CTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.12279636145031114	[518,404]	[446,700,475]	-2	hSpCas9	negative selection	4848738
90264038	90264060	14	+	27760321	HT29	viability after 7 days	TAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-4.436319838795763	[397,310]	[23,0,37]	-9	hSpCas9	negative selection	4848739
90260191	90260213	14	+	27760321	HT29	viability after 25 days	CTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.7385266011601301	[518,404]	[220,467,259]	-6	hSpCas9	negative selection	4932201
90264038	90264060	14	+	27760321	HT29	viability after 25 days	TAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-3.748668734349291	[397,310]	[1,0,95]	-9	hSpCas9	negative selection	4932202
90260191	90260213	14	+	27760321	HT29	viability after 22 days	CTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.35787283738561754	[518,404]	[324,378,549]	-4	hSpCas9	negative selection	5015664
90264038	90264060	14	+	27760321	HT29	viability after 22 days	TAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-5.144258152059119	[397,310]	[0,27,5]	-9	hSpCas9	negative selection	5015665
90260191	90260213	14	+	27760321	HT29	viability after 19 days	CTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.46884569639855284	[518,404]	[446,352,352]	-4	hSpCas9	negative selection	5099127
90264038	90264060	14	+	27760321	HT29	viability after 19 days	TAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-8.663093495339108	[397,310]	[0,0,0]	-9	hSpCas9	negative selection	5099128
90260191	90260213	14	+	27760321	HT29	viability after 16 days	CTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.37382941295085154	[518,404]	[286,553,340]	-4	hSpCas9	negative selection	5182590
90264038	90264060	14	+	27760321	HT29	viability after 16 days	TAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-4.727435283158007	[397,310]	[11,0,31]	-9	hSpCas9	negative selection	5182591
90260191	90260213	14	+	27760321	HT29	viability after 13 days	CTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.49561612301950575	[518,404]	[389,449,304]	-5	hSpCas9	negative selection	5266053
90264038	90264060	14	+	27760321	HT29	viability after 13 days	TAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-6.915457065076153	[397,310]	[1,0,6]	-9	hSpCas9	negative selection	5266054
90260191	90260213	14	+	27760321	HT29	viability after 10 days	CTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.645358903004088	[518,404]	[200,457,447]	-6	hSpCas9	negative selection	5349516
90264038	90264060	14	+	27760321	HT29	viability after 10 days	TAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-8.045348288119804	[397,310]	[1,0,1]	-9	hSpCas9	negative selection	5349517
90260191	90260213	14	+	27760321	MOLM13	viability	CTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	1.2885526744603781	[569,518]	[1132,423]	8	hSpCas9	negative selection	5432979
90264038	90264060	14	+	27760321	MOLM13	viability	TAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-3.8831377021665685	[400,397]	[10,18]	-9	hSpCas9	negative selection	5432980
90256593	90256616	14	+	27661255	K562	viability	GCAAGATGGTGAGTGACTAAGGG	PSMC1	ENSG00000100764	-2.5569384479704054	[234,249]	[47,19]	-9	dCas9-KRAB	negative selection	5504863
90256607	90256630	14	+	27661255	K562	viability	GACTAAGGGTTTCTTTCCGCTGG	PSMC1	ENSG00000100764	-1.3178194685716862	[349,329]	[114,103]	-9	dCas9-KRAB	negative selection	5504864
90256511	90256534	14	-	27661255	K562	viability	GGAAGTCGTTAGGGACGCTACGG	PSMC1	ENSG00000100764	-0.6738405197992073	[435,624]	[291,239]	-8	dCas9-KRAB	negative selection	5504865
90265154	90265177	14	-	27260156	BXPC3	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.5858632905601986	[302]	[81,107,138,93]	-9	hSpCas9	negative selection	5565219
90259154	90259177	14	+	27260156	BXPC3	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.2948701104407534	[32]	[11,32,7,64]	-6	hSpCas9	negative selection	5565220
90263364	90263387	14	+	27260156	BXPC3	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.9077890468767085	[669]	[361,379,324,430]	-9	hSpCas9	negative selection	5629479
90265154	90265177	14	-	27260156	A673	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-0.44918507915983397	[302]	[313,252,288,211]	-8	hSpCas9	negative selection	5686470
90259154	90259177	14	+	27260156	A673	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	0.476395759613069	[32]	[54,65,46,51]	9	hSpCas9	negative selection	5686471
90263364	90263387	14	+	27260156	A673	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.6449772641538009	[669]	[615,467,415,573]	-9	hSpCas9	negative selection	5750730
90265154	90265177	14	-	27260156	A375	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-2.7164202982504575	[302]	[58,48,19,82]	-9	hSpCas9	negative selection	5807721
90259154	90259177	14	+	27260156	A375	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-2.068182107017597	[32]	[1,1,6,22]	-9	hSpCas9	negative selection	5807722
90263364	90263387	14	+	27260156	A375	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.537117015455041	[669]	[346,349,230,172]	-9	hSpCas9	negative selection	5871981
90265154	90265177	14	-	27260156	COLO741	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.129945621295889	[302]	[103,155,257]	-9	hSpCas9	negative selection	5928972
90259154	90259177	14	+	27260156	COLO741	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-1.7622339040984358	[32]	[6,19,9]	-9	hSpCas9	negative selection	5928973
90263364	90263387	14	+	27260156	COLO741	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.8300504724249462	[669]	[573,378,496]	-9	hSpCas9	negative selection	5993232
90265154	90265177	14	-	27260156	CAL120	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.426493478344881	[302]	[77,114,216]	-9	hSpCas9	negative selection	6050223
90259154	90259177	14	+	27260156	CAL120	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.730456476851383	[32]	[42,9,23]	-8	hSpCas9	negative selection	6050224
90263364	90263387	14	+	27260156	CAL120	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.0348534084632526	[669]	[284,272,639]	-8	hSpCas9	negative selection	6114483
90265154	90265177	14	-	27260156	CADOES1	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.0079235354174898	[302]	[201,89,134,132]	-9	hSpCas9	negative selection	6171474
90259154	90259177	14	+	27260156	CADOES1	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.11773794379963132	[32]	[11,34,42,22]	-2	hSpCas9	negative selection	6171475
90263364	90263387	14	+	27260156	CADOES1	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.8280096948635778	[669]	[277,277,396,454]	-8	hSpCas9	negative selection	6235734
90265154	90265177	14	-	27260156	EWS502	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.6341609301522764	[302]	[129,89,138,47]	-9	hSpCas9	negative selection	6292725
90259154	90259177	14	+	27260156	EWS502	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-1.144229124928804	[32]	[7,40,11,0]	-9	hSpCas9	negative selection	6292726
90263364	90263387	14	+	27260156	EWS502	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.3045118415365813	[669]	[228,282,265,383]	-9	hSpCas9	negative selection	6356985
90265154	90265177	14	-	27260156	EW8	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-0.9391607621393636	[302]	[134,211,57,119]	-9	hSpCas9	negative selection	6413976
90259154	90259177	14	+	27260156	EW8	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.4455154408989519	[32]	[20,7,16,32]	-7	hSpCas9	negative selection	6413977
90263364	90263387	14	+	27260156	EW8	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.9750841228845231	[669]	[344,206,157,420]	-9	hSpCas9	negative selection	6478236
90265154	90265177	14	-	27260156	CORL105	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.4989153824914399	[302]	[134,175,71,109]	-9	hSpCas9	negative selection	6535227
90259154	90259177	14	+	27260156	CORL105	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.5525692932318953	[32]	[29,7,8,55]	-7	hSpCas9	negative selection	6535228
90263364	90263387	14	+	27260156	CORL105	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.8747541830541832	[669]	[465,268,497,492]	-9	hSpCas9	negative selection	6599487
90265154	90265177	14	-	27260156	HS294T	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.0072172713977856	[302]	[28,26,86,100]	-9	hSpCas9	negative selection	6656478
90259154	90259177	14	+	27260156	HS294T	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-1.260745122097815	[32]	[2,3,6,7]	-9	hSpCas9	negative selection	6656479
90263364	90263387	14	+	27260156	HS294T	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.1355525478222388	[669]	[64,81,135,209]	-9	hSpCas9	negative selection	6720738
90265154	90265177	14	-	27260156	HCC44	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.9402930790332455	[302]	[157,44,61,98]	-9	hSpCas9	negative selection	6777729
90259154	90259177	14	+	27260156	HCC44	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-1.0914954819711302	[32]	[6,12,51,3]	-8	hSpCas9	negative selection	6777730
90263364	90263387	14	+	27260156	HCC44	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.3786809570292848	[669]	[437,199,317,239]	-9	hSpCas9	negative selection	6841989
90265154	90265177	14	-	27260156	G402	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-2.0982838804613673	[302]	[74,146,18,104]	-9	hSpCas9	negative selection	6898980
90259154	90259177	14	+	27260156	G402	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-2.644939864584813	[32]	[8,0,13,1]	-9	hSpCas9	negative selection	6898981
90263364	90263387	14	+	27260156	G402	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.0653046731077618	[669]	[716,444,175,278]	-8	hSpCas9	negative selection	6963240
90265154	90265177	14	-	27260156	L33	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	0.033437567134658064	[302]	[382,143,150,263]	0	hSpCas9	negative selection	7020231
90259154	90259177	14	+	27260156	L33	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.9030770338852148	[32]	[27,8,10,2]	-9	hSpCas9	negative selection	7020232
90263364	90263387	14	+	27260156	L33	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.39828109333848155	[669]	[444,197,338,566]	-7	hSpCas9	negative selection	7084491
90265154	90265177	14	-	27260156	K562	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-2.271314884566995	[302]	[41,19,39,110]	-9	hSpCas9	negative selection	7141482
90259154	90259177	14	+	27260156	K562	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-2.0010689820657332	[32]	[5,0,6,13]	-9	hSpCas9	negative selection	7141483
90263364	90263387	14	+	27260156	K562	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.6893734072250541	[669]	[248,492,547,199]	-7	hSpCas9	negative selection	7205742
90265154	90265177	14	-	27260156	HT29	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-2.8654938778211783	[302]	[16,45,41,88]	-9	hSpCas9	negative selection	7262733
90259154	90259177	14	+	27260156	HT29	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.8575450305673855	[32]	[39,28,4,16]	-8	hSpCas9	negative selection	7262734
90263364	90263387	14	+	27260156	HT29	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.51185175808308	[669]	[246,361,312,228]	-9	hSpCas9	negative selection	7326993
90265154	90265177	14	-	27260156	MHHES1	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.362312099162074	[302]	[171,59,97,182]	-9	hSpCas9	negative selection	7383984
90259154	90259177	14	+	27260156	MHHES1	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-1.2404779772338395	[32]	[12,21,17,10]	-9	hSpCas9	negative selection	7383985
90263364	90263387	14	+	27260156	MHHES1	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.7896551603318496	[669]	[451,603,414,312]	-9	hSpCas9	negative selection	7448244
90265154	90265177	14	-	27260156	MEWO	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-0.6231910560418894	[302]	[192,146,213]	-8	hSpCas9	negative selection	7505235
90259154	90259177	14	+	27260156	MEWO	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-1.2352791807188876	[32]	[5,4,26]	-9	hSpCas9	negative selection	7505236
90263364	90263387	14	+	27260156	MEWO	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.6212896988993479	[669]	[426,441,356]	-8	hSpCas9	negative selection	7569495
90265154	90265177	14	-	27260156	LNCAPCLONEFGC	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.9700008104058455	[302]	[52,40,93,97]	-9	hSpCas9	negative selection	7626486
90259154	90259177	14	+	27260156	LNCAPCLONEFGC	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-2.6580513064999844	[32]	[1,2,3,9]	-9	hSpCas9	negative selection	7626487
90263364	90263387	14	+	27260156	LNCAPCLONEFGC	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.9954347002355284	[669]	[256,215,423,344]	-8	hSpCas9	negative selection	7690746
90265154	90265177	14	-	27260156	PANC0327	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-2.5288535491178257	[302]	[28,70,64,16]	-9	hSpCas9	negative selection	7747737
90259154	90259177	14	+	27260156	PANC0327	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-1.6904000473263632	[32]	[1,14,15,1]	-9	hSpCas9	negative selection	7747738
90263364	90263387	14	+	27260156	PANC0327	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.2500819503145584	[669]	[292,166,237,316]	-9	hSpCas9	negative selection	7811997
90265154	90265177	14	-	27260156	NCIH2009	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-2.5435270052541448	[302]	[111,44,68]	-9	hSpCas9	negative selection	7868988
90259154	90259177	14	+	27260156	NCIH2009	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	0.30850344682735065	[32]	[149,32,6]	4	hSpCas9	negative selection	7868989
90263364	90263387	14	+	27260156	NCIH2009	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.8332280790099564	[669]	[341,225,235]	-9	hSpCas9	negative selection	7933248
90265154	90265177	14	-	27260156	NCIH1373	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-2.2876746735122433	[302]	[31,25,186,6]	-9	hSpCas9	negative selection	7990239
90259154	90259177	14	+	27260156	NCIH1373	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	0.46382176260832075	[32]	[38,28,64,18]	4	hSpCas9	negative selection	7990240
90263364	90263387	14	+	27260156	NCIH1373	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.6735465959889848	[669]	[106,347,339,26]	-9	hSpCas9	negative selection	8054499
90265154	90265177	14	-	27260156	PATU8902	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-5.911884673133206	[302]	[0,2,0,26]	-9	hSpCas9	negative selection	8111490
90259154	90259177	14	+	27260156	PATU8902	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.5688700812769532	[32]	[50,5,2,75]	-5	hSpCas9	negative selection	8111491
90263364	90263387	14	+	27260156	PATU8902	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.6009891887229872	[669]	[252,319,365,269]	-8	hSpCas9	negative selection	8175750
90265154	90265177	14	-	27260156	PANC1	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-3.4891499645141577	[302]	[18,34,18,21]	-9	hSpCas9	negative selection	8232741
90259154	90259177	14	+	27260156	PANC1	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.402631955025162	[32]	[33,34,18,2]	-6	hSpCas9	negative selection	8232742
90263364	90263387	14	+	27260156	PANC1	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.9978720402697308	[669]	[140,177,112,147]	-9	hSpCas9	negative selection	8297001
90265154	90265177	14	-	27260156	PANC0813	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-2.656926441984794	[302]	[59,61,65,38]	-9	hSpCas9	negative selection	8353992
90259154	90259177	14	+	27260156	PANC0813	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-1.4205901808140884	[32]	[13,15,15,11]	-9	hSpCas9	negative selection	8353993
90263364	90263387	14	+	27260156	PANC0813	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.7418467107575157	[669]	[263,231,239,208]	-9	hSpCas9	negative selection	8418252
90265154	90265177	14	-	27260156	RDES	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.4483445582701788	[302]	[114,131,105,159]	-9	hSpCas9	negative selection	8475243
90259154	90259177	14	+	27260156	RDES	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.06761028545091907	[32]	[25,69,12,31]	-1	hSpCas9	negative selection	8475244
90263364	90263387	14	+	27260156	RDES	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.014609348010164	[669]	[306,319,452,472]	-9	hSpCas9	negative selection	8539503
90265154	90265177	14	-	27260156	PC3	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-0.4967120866765351	[302]	[152,164,335,257]	-8	hSpCas9	negative selection	8596494
90259154	90259177	14	+	27260156	PC3	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-1.0050237023563047	[32]	[7,29,2,20]	-9	hSpCas9	negative selection	8596495
90263364	90263387	14	+	27260156	PC3	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.2430537704011707	[669]	[389,603,1015,430]	-5	hSpCas9	negative selection	8660754
90265154	90265177	14	-	27260156	PATU8988T	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.5439741803114122	[302]	[177,129,24,69]	-9	hSpCas9	negative selection	8717745
90259154	90259177	14	+	27260156	PATU8988T	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-4.38315904392284	[32]	[0,0,2,0]	-9	hSpCas9	negative selection	8717746
90263364	90263387	14	+	27260156	PATU8988T	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.9103623957407324	[669]	[202,525,341,321]	-8	hSpCas9	negative selection	8782005
90265154	90265177	14	-	27260156	T47D	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.271457105480731	[302]	[103,201,149,122]	-9	hSpCas9	negative selection	8838996
90259154	90259177	14	+	27260156	T47D	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.6795216342326724	[32]	[39,4,41,9]	-8	hSpCas9	negative selection	8838997
90263364	90263387	14	+	27260156	T47D	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.818914815629586	[669]	[475,364,386,552]	-9	hSpCas9	negative selection	8903256
90265154	90265177	14	-	27260156	SU8686	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-2.2280400808338214	[302]	[63,62,59,69]	-9	hSpCas9	negative selection	8960247
90259154	90259177	14	+	27260156	SU8686	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.7826713591935301	[32]	[12,4,23,39]	-8	hSpCas9	negative selection	8960248
90263364	90263387	14	+	27260156	SU8686	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-1.686829361439865	[669]	[185,153,227,276]	-9	hSpCas9	negative selection	9024507
90265154	90265177	14	-	27260156	SKES1	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-0.509081073527824	[302]	[251,312,145,160]	-8	hSpCas9	negative selection	9081498
90259154	90259177	14	+	27260156	SKES1	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-1.3008639199664427	[32]	[10,16,17,7]	-9	hSpCas9	negative selection	9081499
90263364	90263387	14	+	27260156	SKES1	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.6623672877913666	[669]	[453,490,439,323]	-8	hSpCas9	negative selection	9145758
90265154	90265177	14	-	27260156	TOV112D	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-0.577938120087427	[302]	[303,280,143,113]	-8	hSpCas9	negative selection	9202749
90259154	90259177	14	+	27260156	TOV112D	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-1.781121991334771	[32]	[0,2,18,12]	-9	hSpCas9	negative selection	9202750
90263364	90263387	14	+	27260156	TOV112D	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.5027732824439244	[669]	[458,498,445,493]	-7	hSpCas9	negative selection	9267009
90265154	90265177	14	-	27260156	TC71	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-0.5010038137301263	[302]	[186,223,260,246]	-8	hSpCas9	negative selection	9324000
90259154	90259177	14	+	27260156	TC71	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	0.08192407668710411	[32]	[79,32,19,14]	2	hSpCas9	negative selection	9324001
90263364	90263387	14	+	27260156	TC71	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.26807542951920926	[669]	[581,611,594,596]	-6	hSpCas9	negative selection	9388260
90265154	90265177	14	-	27260156	TC32	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-0.5722723874621196	[302]	[175,144,316,155]	-8	hSpCas9	negative selection	9445251
90259154	90259177	14	+	27260156	TC32	viability	CTCCAGGGTCAAAGTCAGAGTGG	PSMC1	ENSG00000100764	-0.7306228064956444	[32]	[51,0,1,17]	-9	hSpCas9	negative selection	9445252
90263364	90263387	14	+	27260156	TC32	viability	AATTAAAGACTATCTTCTCATGG	PSMC1	ENSG00000100764	-0.7153764718251565	[669]	[384,264,518,411]	-8	hSpCas9	negative selection	9509511
90263832	90263855	14	-	27869803	HPAFII	viability after 27 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	-4.991282782898891	[87]	[1,0,NaN]	-9	hSpCas9	negative selection	9552693
90263832	90263855	14	-	27869803	HPAFII	viability after 15 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	-0.05555524281516755	[87]	[127,67,NaN]	0	hSpCas9	negative selection	9635142
90263832	90263855	14	-	27869803	ASPC1	viability after 36 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	0.011737748927037162	[342]	[58,103,175]	0	hSpCas9	negative selection	9717591
90263832	90263855	14	-	27869803	PATU8988S	viability after 35 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	-1.3326987080861965	[258]	[3,78,NaN]	-8	hSpCas9	negative selection	9800040
90263832	90263855	14	-	27869803	PATU8988S	viability after 31 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	0.11526021549102305	[258]	[33,210,NaN]	1	hSpCas9	negative selection	9882489
90263832	90263855	14	-	27869803	HPAFII	viability after 35 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	-5.477343065640623	[87]	[0,0,NaN]	-9	hSpCas9	negative selection	9964938
90263832	90263855	14	-	27869803	HPAFII	viability after 31 days	ACCTCACCTTGTGGTTGAGCAGG	PSMC1	ENSG00000100764	-4.595472099128617	[87]	[2,0,NaN]	-9	hSpCas9	negative selection	10047387
90263658	90263681	14	+	28162770	P31FUJ	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-1.7231278309974594	[58]	[20]	-8	hSpCas9	negative selection	10218868
90264088	90264111	14	+	28162770	P31FUJ	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	1.2176592607183658	[175]	[480]	9	hSpCas9	negative selection	10218869
90260190	90260213	14	+	28162770	P31FUJ	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.3785632954037662	[378]	[578]	4	hSpCas9	negative selection	10218870
90259157	90259180	14	+	28162770	P31FUJ	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-1.9222588730066403	[228]	[70]	-8	hSpCas9	negative selection	10218871
90265154	90265177	14	-	28162770	P31FUJ	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	0.32728562766774827	[77]	[114]	3	hSpCas9	negative selection	10218872
90264037	90264060	14	+	28162770	P31FUJ	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-1.120269536759505	[1244]	[672]	-7	hSpCas9	negative selection	10218873
90264118	90264141	14	+	28162770	P31FUJ	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-1.1192396455911788	[463]	[250]	-7	hSpCas9	negative selection	10218874
90263658	90263681	14	+	28162770	TF1	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10388234
90264088	90264111	14	+	28162770	TF1	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10388235
90260190	90260213	14	+	28162770	TF1	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	NaN	[NaN]	[518]	1	hSpCas9	negative selection	10388236
90259157	90259180	14	+	28162770	TF1	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10388237
90265154	90265177	14	-	28162770	TF1	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10388238
90264037	90264060	14	+	28162770	TF1	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	NaN	[NaN]	[455]	1	hSpCas9	negative selection	10388239
90264118	90264141	14	+	28162770	TF1	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	NaN	[NaN]	[157]	1	hSpCas9	negative selection	10388240
90263658	90263681	14	+	28162770	SKM1	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-3.6293566200796095	[6]	[0]	-9	hSpCas9	negative selection	10557600
90264088	90264111	14	+	28162770	SKM1	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	0.6925714748077528	[20]	[59]	6	hSpCas9	negative selection	10557601
90260190	90260213	14	+	28162770	SKM1	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.38690654640190847	[124]	[168]	-3	hSpCas9	negative selection	10557602
90259157	90259180	14	+	28162770	SKM1	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-2.0377303890774425	[71]	[30]	-8	hSpCas9	negative selection	10557603
90265154	90265177	14	-	28162770	SKM1	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.0533272441284613	[26]	[22]	-6	hSpCas9	negative selection	10557604
90264037	90264060	14	+	28162770	SKM1	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-1.4152794669551654	[260]	[172]	-7	hSpCas9	negative selection	10557605
90264118	90264141	14	+	28162770	SKM1	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-2.2625742894079868	[132]	[48]	-8	hSpCas9	negative selection	10557606
90263658	90263681	14	+	28162770	SKM1	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-3.6293566200796095	[6]	[0]	-9	hSpCas9	negative selection	10726966
90264088	90264111	14	+	28162770	SKM1	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	0.6925714748077528	[20]	[59]	6	hSpCas9	negative selection	10726967
90260190	90260213	14	+	28162770	SKM1	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.38690654640190847	[124]	[168]	-3	hSpCas9	negative selection	10726968
90259157	90259180	14	+	28162770	SKM1	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-2.0377303890774425	[71]	[30]	-8	hSpCas9	negative selection	10726969
90265154	90265177	14	-	28162770	SKM1	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-1.0533272441284613	[26]	[22]	-6	hSpCas9	negative selection	10726970
90264037	90264060	14	+	28162770	SKM1	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-1.4152794669551654	[260]	[172]	-7	hSpCas9	negative selection	10726971
90264118	90264141	14	+	28162770	SKM1	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-2.2625742894079868	[132]	[48]	-8	hSpCas9	negative selection	10726972
90263658	90263681	14	+	28162770	PL21	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-4.472285727482176	[50]	[0]	-9	hSpCas9	negative selection	10896332
90264088	90264111	14	+	28162770	PL21	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	1.4725118849024503	[76]	[92]	9	hSpCas9	negative selection	10896333
90260190	90260213	14	+	28162770	PL21	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.46467619392105075	[389]	[122]	-3	hSpCas9	negative selection	10896334
90259157	90259180	14	+	28162770	PL21	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-0.26283236185322567	[203]	[73]	-2	hSpCas9	negative selection	10896335
90265154	90265177	14	-	28162770	PL21	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	0.792481645576074	[64]	[48]	6	hSpCas9	negative selection	10896336
90264037	90264060	14	+	28162770	PL21	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-0.8606317108404808	[896]	[214]	-5	hSpCas9	negative selection	10896337
90264118	90264141	14	+	28162770	PL21	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-0.481684425484425	[384]	[119]	-3	hSpCas9	negative selection	10896338
90263658	90263681	14	+	28162770	P31FUJ	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-1.7231278309974594	[58]	[20]	-8	hSpCas9	negative selection	11065698
90264088	90264111	14	+	28162770	P31FUJ	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	1.2176592607183658	[175]	[480]	9	hSpCas9	negative selection	11065699
90260190	90260213	14	+	28162770	P31FUJ	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.3785632954037662	[378]	[578]	4	hSpCas9	negative selection	11065700
90259157	90259180	14	+	28162770	P31FUJ	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-1.9222588730066403	[228]	[70]	-8	hSpCas9	negative selection	11065701
90265154	90265177	14	-	28162770	P31FUJ	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	0.32728562766774827	[77]	[114]	3	hSpCas9	negative selection	11065702
90264037	90264060	14	+	28162770	P31FUJ	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-1.120269536759505	[1244]	[672]	-7	hSpCas9	negative selection	11065703
90264118	90264141	14	+	28162770	P31FUJ	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-1.1192396455911788	[463]	[250]	-7	hSpCas9	negative selection	11065704
90263658	90263681	14	+	28162770	OCIAML5	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-5.606954073027465	[26]	[0]	-9	hSpCas9	negative selection	11235064
90264088	90264111	14	+	28162770	OCIAML5	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	0.5500318727073487	[83]	[221]	5	hSpCas9	negative selection	11235065
90260190	90260213	14	+	28162770	OCIAML5	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.19023530675857028	[133]	[211]	-1	hSpCas9	negative selection	11235066
90259157	90259180	14	+	28162770	OCIAML5	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-3.4114939794780157	[111]	[18]	-9	hSpCas9	negative selection	11235067
90265154	90265177	14	-	28162770	OCIAML5	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	0.2502951467656809	[33]	[72]	2	hSpCas9	negative selection	11235068
90264037	90264060	14	+	28162770	OCIAML5	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-1.7099082088274047	[646]	[356]	-7	hSpCas9	negative selection	11235069
90264118	90264141	14	+	28162770	OCIAML5	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-2.1063837595966817	[395]	[165]	-8	hSpCas9	negative selection	11235070
90263658	90263681	14	+	28162770	EOL1	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-3.0095642927730086	[106]	[6]	-9	hSpCas9	negative selection	11404430
90264088	90264111	14	+	28162770	EOL1	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	-0.14054725665135037	[135]	[64]	-1	hSpCas9	negative selection	11404431
90260190	90260213	14	+	28162770	EOL1	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.7366148209774599	[785]	[689]	6	hSpCas9	negative selection	11404432
90259157	90259180	14	+	28162770	EOL1	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-3.109940604814756	[507]	[30]	-9	hSpCas9	negative selection	11404433
90265154	90265177	14	-	28162770	EOL1	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-0.4035064261136694	[117]	[46]	-3	hSpCas9	negative selection	11404434
90264037	90264060	14	+	28162770	EOL1	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-2.0211353070350433	[1224]	[158]	-8	hSpCas9	negative selection	11404435
90264118	90264141	14	+	28162770	EOL1	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-1.1351584745537333	[591]	[141]	-6	hSpCas9	negative selection	11404436
90263658	90263681	14	+	28162770	MOLM13	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-4.096895237238947	[70]	[2]	-9	hSpCas9	negative selection	11573796
90264088	90264111	14	+	28162770	MOLM13	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	-1.1354516484914323	[157]	[51]	-5	hSpCas9	negative selection	11573797
90260190	90260213	14	+	28162770	MOLM13	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.5161624922231096	[528]	[546]	4	hSpCas9	negative selection	11573798
90259157	90259180	14	+	28162770	MOLM13	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-2.7880088430075864	[362]	[37]	-8	hSpCas9	negative selection	11573799
90265154	90265177	14	-	28162770	MOLM13	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-0.10634671258351869	[66]	[44]	0	hSpCas9	negative selection	11573800
90264037	90264060	14	+	28162770	MOLM13	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-2.4123206712885397	[1258]	[170]	-8	hSpCas9	negative selection	11573801
90264118	90264141	14	+	28162770	MOLM13	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-1.3419170195071217	[588]	[167]	-6	hSpCas9	negative selection	11573802
90263658	90263681	14	+	28162770	HEL	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-3.8166927866369402	[87]	[3]	-9	hSpCas9	negative selection	11743162
90264088	90264111	14	+	28162770	HEL	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	0.7573813979414799	[132]	[143]	6	hSpCas9	negative selection	11743163
90260190	90260213	14	+	28162770	HEL	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.1921806163702494	[465]	[340]	1	hSpCas9	negative selection	11743164
90259157	90259180	14	+	28162770	HEL	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-3.211410301536188	[375]	[25]	-9	hSpCas9	negative selection	11743165
90265154	90265177	14	-	28162770	HEL	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	0.8808985691951213	[77]	[91]	7	hSpCas9	negative selection	11743166
90264037	90264060	14	+	28162770	HEL	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-1.8363025357048373	[1036]	[185]	-7	hSpCas9	negative selection	11743167
90264118	90264141	14	+	28162770	HEL	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-2.7765456383786726	[566]	[52]	-8	hSpCas9	negative selection	11743168
90263658	90263681	14	+	28162770	MV411	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-1.4783874857782306	[42]	[12]	-7	hSpCas9	negative selection	11912528
90264088	90264111	14	+	28162770	MV411	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	0.8927726694834133	[77]	[121]	7	hSpCas9	negative selection	11912529
90260190	90260213	14	+	28162770	MV411	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.28274185039075594	[477]	[330]	-2	hSpCas9	negative selection	11912530
90259157	90259180	14	+	28162770	MV411	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-2.2172307162206693	[275]	[49]	-8	hSpCas9	negative selection	11912531
90265154	90265177	14	-	28162770	MV411	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	0.6562430963501045	[57]	[76]	6	hSpCas9	negative selection	11912532
90264037	90264060	14	+	28162770	MV411	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-1.0223542212263275	[855]	[354]	-6	hSpCas9	negative selection	11912533
90264118	90264141	14	+	28162770	MV411	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-0.8494239884698136	[384]	[179]	-5	hSpCas9	negative selection	11912534
90263658	90263681	14	+	28162770	MONOMAC1	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-1.5596069264442618	[35]	[13]	-8	hSpCas9	negative selection	12081894
90264088	90264111	14	+	28162770	MONOMAC1	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	1.5591533143715512	[81]	[276]	9	hSpCas9	negative selection	12081895
90260190	90260213	14	+	28162770	MONOMAC1	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	-0.0653311678477313	[271]	[297]	0	hSpCas9	negative selection	12081896
90259157	90259180	14	+	28162770	MONOMAC1	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-1.4782185996036068	[191]	[78]	-8	hSpCas9	negative selection	12081897
90265154	90265177	14	-	28162770	MONOMAC1	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	-0.7640774397834476	[39]	[26]	-6	hSpCas9	negative selection	12081898
90264037	90264060	14	+	28162770	MONOMAC1	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-1.2309841789828915	[558]	[272]	-7	hSpCas9	negative selection	12081899
90264118	90264141	14	+	28162770	MONOMAC1	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-1.6105581138910172	[316]	[118]	-8	hSpCas9	negative selection	12081900
90263658	90263681	14	+	28162770	OCIAML2	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-4.4706298252421615	[7]	[1]	-9	hSpCas9	negative selection	12251260
90264088	90264111	14	+	28162770	OCIAML2	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	0.5399394164680261	[16]	[136]	5	hSpCas9	negative selection	12251261
90260190	90260213	14	+	28162770	OCIAML2	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.41903039970463674	[72]	[540]	4	hSpCas9	negative selection	12251262
90259157	90259180	14	+	28162770	OCIAML2	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-2.4078940698941986	[44]	[46]	-8	hSpCas9	negative selection	12251263
90265154	90265177	14	-	28162770	OCIAML2	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	0.18648246123483014	[12]	[81]	1	hSpCas9	negative selection	12251264
90264037	90264060	14	+	28162770	OCIAML2	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-1.278611052949232	[143]	[328]	-7	hSpCas9	negative selection	12251265
90264118	90264141	14	+	28162770	OCIAML2	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-0.9188341884562043	[87]	[257]	-6	hSpCas9	negative selection	12251266
90263658	90263681	14	+	28162770	OCIAML3	viability	GTAGGAGGAAAGATCAAAAGTGG	PSMC1	ENSG00000100764	-5.681470481574503	[16]	[0]	-9	hSpCas9	negative selection	12420626
90264088	90264111	14	+	28162770	OCIAML3	viability	CACAGTGATGAAGGTAGAAAAGG	PSMC1	ENSG00000100764	0.4958778631930321	[34]	[148]	4	hSpCas9	negative selection	12420627
90260190	90260213	14	+	28162770	OCIAML3	viability	GCTGCCAGCAAACTGCCACTGGG	PSMC1	ENSG00000100764	0.18297363268992217	[95]	[328]	1	hSpCas9	negative selection	12420628
90259157	90259180	14	+	28162770	OCIAML3	viability	CAGGGTCAAAGTCAGAGTGGTGG	PSMC1	ENSG00000100764	-1.3482512259222046	[69]	[82]	-7	hSpCas9	negative selection	12420629
90265154	90265177	14	-	28162770	OCIAML3	viability	CAGAGCATACCTGTGCCAGGTGG	PSMC1	ENSG00000100764	1.5164163493694875	[10]	[94]	9	hSpCas9	negative selection	12420630
90264037	90264060	14	+	28162770	OCIAML3	viability	TTAGGTGCATGCCGTGATAGGGG	PSMC1	ENSG00000100764	-0.5526110184929949	[291]	[600]	-4	hSpCas9	negative selection	12420631
90264118	90264141	14	+	28162770	OCIAML3	viability	GGAGACCTATGCAGATATTGGGG	PSMC1	ENSG00000100764	-1.403064857612768	[105]	[120]	-7	hSpCas9	negative selection	12420632