Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5770
• Symbol: PTPN1
• Description: protein tyrosine phosphatase non-receptor type 1

DataSource: http://genomecrispr.dkfz.de/#!/results/PTPN1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
50568418	50568441	20	+	26472758	Jiyoye	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	-0.9596069491657493	[48]	[18]	-6	hSpCas9	negative selection	130948
50561389	50561412	20	-	26472758	Jiyoye	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	0.6071760468536238	[268]	[308]	4	hSpCas9	negative selection	130949
50579837	50579860	20	+	26472758	Jiyoye	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-4.506568885143707	[210]	[6]	-9	hSpCas9	negative selection	130950
50581346	50581369	20	+	26472758	Jiyoye	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	0.46527833606944163	[145]	[151]	3	hSpCas9	negative selection	130951
50581438	50581461	20	-	26472758	Jiyoye	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	0.631390538449139	[112]	[131]	4	hSpCas9	negative selection	130952
50581448	50581471	20	-	26472758	Jiyoye	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	-0.5286942810744111	[87]	[45]	-4	hSpCas9	negative selection	130953
50568402	50568425	20	+	26472758	Jiyoye	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	0.9477437628685763	[120]	[175]	6	hSpCas9	negative selection	130954
50578598	50578621	20	-	26472758	Jiyoye	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	-0.00786211777297019	[67]	[50]	0	hSpCas9	negative selection	130955
50579689	50579712	20	+	26472758	Jiyoye	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	0.2635845278770236	[94]	[85]	2	hSpCas9	negative selection	130956
50579815	50579838	20	+	26472758	Jiyoye	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	-0.2897555508580803	[153]	[94]	-2	hSpCas9	negative selection	130957
50568418	50568441	20	+	26472758	KBM7	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	1.2328774254651407	[84,43]	[138,6]	9	hSpCas9	negative selection	322066
50561389	50561412	20	-	26472758	KBM7	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	1.0596819084262432	[1072,1121]	[1548,666]	9	hSpCas9	negative selection	322067
50579837	50579860	20	+	26472758	KBM7	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-1.4595172100190488	[569,325]	[77,71]	-7	hSpCas9	negative selection	322068
50581346	50581369	20	+	26472758	KBM7	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	0.004267415153124447	[522,465]	[280,189]	0	hSpCas9	negative selection	322069
50581438	50581461	20	-	26472758	KBM7	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	1.2875827655245016	[720,400]	[962,328]	9	hSpCas9	negative selection	322070
50581448	50581471	20	-	26472758	KBM7	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	1.3288053991622384	[124,89]	[210,48]	9	hSpCas9	negative selection	322071
50568402	50568425	20	+	26472758	KBM7	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	1.1183047278131517	[834,865]	[1100,670]	9	hSpCas9	negative selection	322072
50578598	50578621	20	-	26472758	KBM7	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	0.854991412402667	[218,198]	[210,147]	8	hSpCas9	negative selection	322073
50579689	50579712	20	+	26472758	KBM7	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	0.9743476369238906	[362,383]	[305,384]	9	hSpCas9	negative selection	322074
50579815	50579838	20	+	26472758	KBM7	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	0.3691018773802795	[582,577]	[446,270]	4	hSpCas9	negative selection	322075
50568418	50568441	20	+	26472758	Raji	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	1.0600778205952426	[30]	[14]	8	hSpCas9	negative selection	513184
50561389	50561412	20	-	26472758	Raji	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	-0.142711814752696	[665]	[139]	-1	hSpCas9	negative selection	513185
50579837	50579860	20	+	26472758	Raji	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-2.031380534582252	[228]	[12]	-8	hSpCas9	negative selection	513186
50581346	50581369	20	+	26472758	Raji	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	0.04983251281144113	[178]	[42]	0	hSpCas9	negative selection	513187
50581438	50581461	20	-	26472758	Raji	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	0.7680733622580006	[166]	[65]	7	hSpCas9	negative selection	513188
50581448	50581471	20	-	26472758	Raji	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	0.2708822676564787	[99]	[27]	2	hSpCas9	negative selection	513189
50568402	50568425	20	+	26472758	Raji	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	-0.5130278013518464	[411]	[66]	-4	hSpCas9	negative selection	513190
50578598	50578621	20	-	26472758	Raji	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	-0.2324664675110253	[80]	[15]	-2	hSpCas9	negative selection	513191
50579689	50579712	20	+	26472758	Raji	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	0.13863446935803914	[136]	[34]	1	hSpCas9	negative selection	513192
50579815	50579838	20	+	26472758	Raji	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	0.23291441745745833	[219]	[59]	2	hSpCas9	negative selection	513193
50568418	50568441	20	+	26472758	K562	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	-6.21501289097085	[87]	[0]	-9	hSpCas9	negative selection	704302
50561389	50561412	20	-	26472758	K562	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	-1.3435746461040878	[952]	[316]	-6	hSpCas9	negative selection	704303
50579837	50579860	20	+	26472758	K562	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-3.178113308159321	[385]	[35]	-8	hSpCas9	negative selection	704304
50581346	50581369	20	+	26472758	K562	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	-2.4063458314504556	[470]	[74]	-8	hSpCas9	negative selection	704305
50581438	50581461	20	-	26472758	K562	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	-1.422597988937195	[415]	[130]	-6	hSpCas9	negative selection	704306
50581448	50581471	20	-	26472758	K562	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	-4.5104687744970215	[107]	[3]	-9	hSpCas9	negative selection	704307
50568402	50568425	20	+	26472758	K562	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	-2.4504051988726845	[640]	[98]	-8	hSpCas9	negative selection	704308
50578598	50578621	20	-	26472758	K562	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	-2.2665431916109324	[227]	[39]	-7	hSpCas9	negative selection	704309
50579689	50579712	20	+	26472758	K562	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	-0.47264730906205443	[239]	[145]	-3	hSpCas9	negative selection	704310
50579815	50579838	20	+	26472758	K562	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	-0.6601909266908332	[394]	[210]	-4	hSpCas9	negative selection	704311
50510521	50510544	20	+	26627737	DLD1	viability	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	1.8809322562631237	[279]	[380,223,352]	9	hSpCas9	negative selection	815079
50561380	50561403	20	+	26627737	DLD1	viability	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.013265128981119867	[1000]	[342,277,307]	0	hSpCas9	negative selection	815081
50568383	50568406	20	-	26627737	DLD1	viability	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	-0.012926226688973363	[1314]	[398,441,385]	0	hSpCas9	negative selection	815082
50579278	50579301	20	-	26627737	DLD1	viability	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	-0.23683819452882415	[830]	[143,149,344]	-2	hSpCas9	negative selection	815083
50579766	50579789	20	-	26627737	DLD1	viability	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	-1.0628477138216	[636]	[103,53,121]	-7	hSpCas9	negative selection	815084
50581304	50581327	20	+	26627737	DLD1	viability	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	2.0974935265521517	[28]	[0,123,0]	9	hSpCas9	negative selection	815085
50510521	50510544	20	+	26627737	GBM cells	viability after 5 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.7648529521509915	[292]	[297,235]	8	hSpCas9	negative selection	897394
50561380	50561403	20	+	26627737	GBM cells	viability after 5 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.1328448455629725	[642]	[351,276]	-2	hSpCas9	negative selection	897396
50568383	50568406	20	-	26627737	GBM cells	viability after 5 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.4525802451173031	[465]	[392,290]	6	hSpCas9	negative selection	897397
50579278	50579301	20	-	26627737	GBM cells	viability after 5 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.6748413613122106	[357]	[368,243]	8	hSpCas9	negative selection	897398
50579766	50579789	20	-	26627737	GBM cells	viability after 5 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.22955918687415705	[263]	[138,192]	3	hSpCas9	negative selection	897399
50581304	50581327	20	+	26627737	GBM cells	viability after 5 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-3.0396855804501715	[22]	[0,1]	-9	hSpCas9	negative selection	897400
50510521	50510544	20	+	26627737	GBM cells	viability after 13 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.8164398441678771	[292]	[274,283]	8	hSpCas9	negative selection	979709
50561380	50561403	20	+	26627737	GBM cells	viability after 13 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.18527191739466597	[642]	[388,239]	-2	hSpCas9	negative selection	979711
50568383	50568406	20	-	26627737	GBM cells	viability after 13 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.4756297929786577	[465]	[414,299]	6	hSpCas9	negative selection	979712
50579278	50579301	20	-	26627737	GBM cells	viability after 13 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.6584112728947134	[357]	[369,254]	7	hSpCas9	negative selection	979713
50579766	50579789	20	-	26627737	GBM cells	viability after 13 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.5840751261040115	[263]	[222,207]	7	hSpCas9	negative selection	979714
50581304	50581327	20	+	26627737	GBM cells	viability after 13 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-1.3604152122212132	[22]	[0,7]	-8	hSpCas9	negative selection	979715
50510521	50510544	20	+	26627737	GBM cells	viability after 21 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.8013582078635075	[292]	[302,253]	7	hSpCas9	negative selection	1062024
50561380	50561403	20	+	26627737	GBM cells	viability after 21 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.41336763033466706	[642]	[266,257]	-4	hSpCas9	negative selection	1062026
50568383	50568406	20	-	26627737	GBM cells	viability after 21 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.6845776251477262	[465]	[420,393]	7	hSpCas9	negative selection	1062027
50579278	50579301	20	-	26627737	GBM cells	viability after 21 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.7104090415162096	[357]	[335,301]	7	hSpCas9	negative selection	1062028
50579766	50579789	20	-	26627737	GBM cells	viability after 21 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.6767919018219273	[263]	[257,202]	6	hSpCas9	negative selection	1062029
50581304	50581327	20	+	26627737	GBM cells	viability after 21 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	1.063877070881992	[22]	[34,17]	9	hSpCas9	negative selection	1062030
50510521	50510544	20	+	26627737	RPE1	viability after 9 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.15333886574865457	[1001]	[316,389]	1	hSpCas9	negative selection	1144339
50561380	50561403	20	+	26627737	RPE1	viability after 9 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-1.5793897596849662	[2474]	[274,238]	-8	hSpCas9	negative selection	1144341
50568383	50568406	20	-	26627737	RPE1	viability after 9 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	-2.1327977859907117	[2810]	[187,216]	-9	hSpCas9	negative selection	1144342
50579278	50579301	20	-	26627737	RPE1	viability after 9 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.4279827603925533	[689]	[349,213]	3	hSpCas9	negative selection	1144343
50579766	50579789	20	-	26627737	RPE1	viability after 9 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.829647690200445	[544]	[328,269]	5	hSpCas9	negative selection	1144344
50581304	50581327	20	+	26627737	RPE1	viability after 9 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-6.514378028565198	[291]	[0,0]	-9	hSpCas9	negative selection	1144345
50510521	50510544	20	+	26627737	RPE1	viability after 12 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	-0.4739179439038379	[1001]	[204,181]	-3	hSpCas9	negative selection	1226654
50561380	50561403	20	+	26627737	RPE1	viability after 12 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-2.073320650004094	[2474]	[208,103]	-8	hSpCas9	negative selection	1226656
50568383	50568406	20	-	26627737	RPE1	viability after 12 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	-2.3879716711256522	[2810]	[153,133]	-9	hSpCas9	negative selection	1226657
50579278	50579301	20	-	26627737	RPE1	viability after 12 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.2205463621710752	[689]	[249,179]	1	hSpCas9	negative selection	1226658
50579766	50579789	20	-	26627737	RPE1	viability after 12 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.8024523044588927	[544]	[267,241]	5	hSpCas9	negative selection	1226659
50581304	50581327	20	+	26627737	RPE1	viability after 12 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-6.29371314720688	[291]	[0,0]	-9	hSpCas9	negative selection	1226660
50510521	50510544	20	+	26627737	RPE1	viability after 15 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	-0.5316419794422043	[1001]	[247,145]	-3	hSpCas9	negative selection	1308969
50561380	50561403	20	+	26627737	RPE1	viability after 15 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-1.6872528030710736	[2474]	[222,211]	-8	hSpCas9	negative selection	1308971
50568383	50568406	20	-	26627737	RPE1	viability after 15 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	-2.1302863985520726	[2810]	[286,79]	-8	hSpCas9	negative selection	1308972
50579278	50579301	20	-	26627737	RPE1	viability after 15 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.17458348430213722	[689]	[259,181]	1	hSpCas9	negative selection	1308973
50579766	50579789	20	-	26627737	RPE1	viability after 15 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	1.5863849874124551	[544]	[661,270]	8	hSpCas9	negative selection	1308974
50581304	50581327	20	+	26627737	RPE1	viability after 15 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-6.368075685008123	[291]	[0,0]	-9	hSpCas9	negative selection	1308975
50510521	50510544	20	+	26627737	RPE1	viability after 18 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	-0.46073482203445837	[1001]	[195,196]	-3	hSpCas9	negative selection	1391284
50561380	50561403	20	+	26627737	RPE1	viability after 18 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-2.1977061808874137	[2474]	[162,126]	-8	hSpCas9	negative selection	1391286
50568383	50568406	20	-	26627737	RPE1	viability after 18 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	-2.6200784680978906	[2810]	[61,188]	-8	hSpCas9	negative selection	1391287
50579278	50579301	20	-	26627737	RPE1	viability after 18 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	-0.33271755505058365	[689]	[201,89]	-2	hSpCas9	negative selection	1391288
50579766	50579789	20	-	26627737	RPE1	viability after 18 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	1.172431213358721	[544]	[418,237]	6	hSpCas9	negative selection	1391289
50581304	50581327	20	+	26627737	RPE1	viability after 18 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-6.3001562987792745	[291]	[0,0]	-9	hSpCas9	negative selection	1391290
50510521	50510544	20	+	26627737	HeLa	viability after 8 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.44621376734818247	[514]	[368,181,373]	4	hSpCas9	negative selection	1473599
50561380	50561403	20	+	26627737	HeLa	viability after 8 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.12840412875055507	[933]	[280,376,432]	-1	hSpCas9	negative selection	1473601
50568383	50568406	20	-	26627737	HeLa	viability after 8 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	-0.2727489585429943	[860]	[347,151,429]	-3	hSpCas9	negative selection	1473602
50579278	50579301	20	-	26627737	HeLa	viability after 8 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	-0.16478633416476862	[540]	[412,100,163]	-1	hSpCas9	negative selection	1473603
50579766	50579789	20	-	26627737	HeLa	viability after 8 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.9584882863176678	[325]	[437,182,243]	7	hSpCas9	negative selection	1473604
50581304	50581327	20	+	26627737	HeLa	viability after 8 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	0.06778426246572433	[37]	[11,38,0]	0	hSpCas9	negative selection	1473605
50510521	50510544	20	+	26627737	HeLa	viability after 12 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	-0.049270030545823906	[514]	[220,200,195]	0	hSpCas9	negative selection	1555914
50561380	50561403	20	+	26627737	HeLa	viability after 12 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.2241059768746012	[933]	[414,224,364]	-2	hSpCas9	negative selection	1555916
50568383	50568406	20	-	26627737	HeLa	viability after 12 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.1274215469625528	[860]	[746,156,296]	1	hSpCas9	negative selection	1555917
50579278	50579301	20	-	26627737	HeLa	viability after 12 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	-0.11175687095363623	[540]	[155,331,117]	-1	hSpCas9	negative selection	1555918
50579766	50579789	20	-	26627737	HeLa	viability after 12 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	1.452106354393498	[325]	[556,248,317]	8	hSpCas9	negative selection	1555919
50581304	50581327	20	+	26627737	HeLa	viability after 12 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-0.1398414661524563	[37]	[42,0,0]	-1	hSpCas9	negative selection	1555920
50510521	50510544	20	+	26627737	HeLa	viability after 15 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.48466749008844695	[514]	[381,190,306]	4	hSpCas9	negative selection	1638229
50561380	50561403	20	+	26627737	HeLa	viability after 15 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.27261560278332	[933]	[260,356,327]	-2	hSpCas9	negative selection	1638231
50568383	50568406	20	-	26627737	HeLa	viability after 15 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	-0.5905985237019461	[860]	[280,179,236]	-5	hSpCas9	negative selection	1638232
50579278	50579301	20	-	26627737	HeLa	viability after 15 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.4798335599667442	[540]	[344,388,176]	4	hSpCas9	negative selection	1638233
50579766	50579789	20	-	26627737	HeLa	viability after 15 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.6723551760622952	[325]	[201,252,176]	5	hSpCas9	negative selection	1638234
50581304	50581327	20	+	26627737	HeLa	viability after 15 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-3.95139440113558	[37]	[0,0,0]	-9	hSpCas9	negative selection	1638235
50510521	50510544	20	+	26627737	HeLa	viability after 18 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.5046728256658208	[514]	[257,165,306]	4	hSpCas9	negative selection	1720544
50561380	50561403	20	+	26627737	HeLa	viability after 18 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.2299132083454709	[933]	[189,299,327]	-2	hSpCas9	negative selection	1720546
50568383	50568406	20	-	26627737	HeLa	viability after 18 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	-0.6110646320528598	[860]	[178,152,236]	-5	hSpCas9	negative selection	1720547
50579278	50579301	20	-	26627737	HeLa	viability after 18 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.4565484782528611	[540]	[233,306,176]	4	hSpCas9	negative selection	1720548
50579766	50579789	20	-	26627737	HeLa	viability after 18 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.6197618544161735	[325]	[121,207,176]	5	hSpCas9	negative selection	1720549
50581304	50581327	20	+	26627737	HeLa	viability after 18 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-3.6411887494817132	[37]	[0,0,0]	-9	hSpCas9	negative selection	1720550
50510521	50510544	20	+	26627737	HCT116	viability after 6 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.414123896517096	[560]	[83,135]	2	hSpCas9	negative selection	1802859
50561380	50561403	20	+	26627737	HCT116	viability after 6 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	0.7425554870594773	[1211]	[370,289]	4	hSpCas9	negative selection	1802861
50568383	50568406	20	-	26627737	HCT116	viability after 6 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.7293710976700032	[1401]	[425,331]	4	hSpCas9	negative selection	1802862
50579278	50579301	20	-	26627737	HCT116	viability after 6 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	1.986310852870131	[534]	[592,189]	8	hSpCas9	negative selection	1802863
50579766	50579789	20	-	26627737	HCT116	viability after 6 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	-0.6074101262685248	[702]	[165,20]	-3	hSpCas9	negative selection	1802864
50581304	50581327	20	+	26627737	HCT116	viability after 6 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-1.70568873496694	[188]	[21,1]	-7	hSpCas9	negative selection	1802865
50510521	50510544	20	+	26627737	HCT116	viability after 8 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.4813781063257528	[325]	[243,155,350]	5	hSpCas9	negative selection	1885174
50561380	50561403	20	+	26627737	HCT116	viability after 8 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	0.056107907284330016	[729]	[453,362,437]	0	hSpCas9	negative selection	1885176
50568383	50568406	20	-	26627737	HCT116	viability after 8 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.3449440046127664	[590]	[469,369,401]	4	hSpCas9	negative selection	1885177
50579278	50579301	20	-	26627737	HCT116	viability after 8 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.33133441945978037	[495]	[321,346,361]	3	hSpCas9	negative selection	1885178
50579766	50579789	20	-	26627737	HCT116	viability after 8 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.41020977785341073	[311]	[239,250,194]	4	hSpCas9	negative selection	1885179
50581304	50581327	20	+	26627737	HCT116	viability after 8 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-1.4187150005908125	[181]	[45,54,11]	-9	hSpCas9	negative selection	1885180
50510521	50510544	20	+	26627737	HCT116	viability after 9 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.5732748642583019	[560]	[223,221]	4	hSpCas9	negative selection	1967489
50561380	50561403	20	+	26627737	HCT116	viability after 9 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	1.4584547355671917	[1211]	[737,1008]	8	hSpCas9	negative selection	1967491
50568383	50568406	20	-	26627737	HCT116	viability after 9 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.11359354784790265	[1401]	[523,310]	0	hSpCas9	negative selection	1967492
50579278	50579301	20	-	26627737	HCT116	viability after 9 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.2008892158665687	[534]	[209,127]	1	hSpCas9	negative selection	1967493
50579766	50579789	20	-	26627737	HCT116	viability after 9 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	-1.212541064834442	[702]	[142,31]	-7	hSpCas9	negative selection	1967494
50581304	50581327	20	+	26627737	HCT116	viability after 9 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-1.6967809770542415	[188]	[33,0]	-8	hSpCas9	negative selection	1967495
50510521	50510544	20	+	26627737	HCT116	viability after 12 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.30528997855202383	[325]	[131,207,301]	3	hSpCas9	negative selection	2049804
50561380	50561403	20	+	26627737	HCT116	viability after 12 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	0.06197815855476896	[729]	[364,501,339]	0	hSpCas9	negative selection	2049806
50568383	50568406	20	-	26627737	HCT116	viability after 12 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.6201543434758233	[590]	[530,417,476]	6	hSpCas9	negative selection	2049807
50579278	50579301	20	-	26627737	HCT116	viability after 12 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.6414106318406297	[495]	[287,480,462]	6	hSpCas9	negative selection	2049808
50579766	50579789	20	-	26627737	HCT116	viability after 12 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.5141641103892626	[311]	[231,287,183]	5	hSpCas9	negative selection	2049809
50581304	50581327	20	+	26627737	HCT116	viability after 12 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-1.6891390183534898	[181]	[16,66,6]	-9	hSpCas9	negative selection	2049810
50510521	50510544	20	+	26627737	HCT116	viability after 15 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.7218295048219199	[325]	[455,158,328]	6	hSpCas9	negative selection	2132119
50561380	50561403	20	+	26627737	HCT116	viability after 15 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.0744238411259186	[729]	[402,388,402]	0	hSpCas9	negative selection	2132121
50568383	50568406	20	-	26627737	HCT116	viability after 15 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.17289063730745313	[590]	[425,249,475]	1	hSpCas9	negative selection	2132122
50579278	50579301	20	-	26627737	HCT116	viability after 15 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.4759889774686682	[495]	[396,339,450]	4	hSpCas9	negative selection	2132123
50579766	50579789	20	-	26627737	HCT116	viability after 15 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.7297647804612076	[311]	[282,332,273]	6	hSpCas9	negative selection	2132124
50581304	50581327	20	+	26627737	HCT116	viability after 15 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-1.4416557004031212	[181]	[63,53,0]	-8	hSpCas9	negative selection	2132125
50510521	50510544	20	+	26627737	HCT116	viability after 18 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.04147022092029792	[325]	[139,107,245]	0	hSpCas9	negative selection	2214434
50561380	50561403	20	+	26627737	HCT116	viability after 18 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	0.029731253810541647	[729]	[406,347,324]	0	hSpCas9	negative selection	2214436
50568383	50568406	20	-	26627737	HCT116	viability after 18 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.4231158004848764	[590]	[483,172,511]	3	hSpCas9	negative selection	2214437
50579278	50579301	20	-	26627737	HCT116	viability after 18 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.5370966542817736	[495]	[373,335,333]	4	hSpCas9	negative selection	2214438
50579766	50579789	20	-	26627737	HCT116	viability after 18 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.7623923340731568	[311]	[353,194,220]	6	hSpCas9	negative selection	2214439
50581304	50581327	20	+	26627737	HCT116	viability after 18 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-2.6845125478989216	[181]	[17,20,0]	-9	hSpCas9	negative selection	2214440
50524717	50524740	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGCCTGCCACTACGCCCAG	PTPN1	ENSG00000196396	0.535464235425859	[718,90]	[215,31]	2	dCas9-VP64	positive selection	2386843
50529999	50530022	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTAGCTGGGATTACAGGCGG	PTPN1	ENSG00000196396	-1.0771701610192164	[3,202]	[1,19]	-6	dCas9-VP64	positive selection	2427125
50520325	50520348	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	CATACCATTGCACTACAGCCTGG	PTPN1	ENSG00000196396	0.3236756889793352	[35,116]	[8,33]	1	dCas9-VP64	positive selection	2428056
50544802	50544825	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACTAGCCTGGCCAACACAG	PTPN1	ENSG00000196396	0.3601150748164519	[269,268]	[95,53]	1	dCas9-VP64	positive selection	2458923
50524717	50524740	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGCCTGCCACTACGCCCAG	PTPN1	ENSG00000196396	-0.3318057288001406	[240,185]	[44,64]	-3	dCas9-VP64	positive selection	2482098
50529999	50530022	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTAGCTGGGATTACAGGCGG	PTPN1	ENSG00000196396	0.14665344663969582	[27,75]	[10,24]	1	dCas9-VP64	positive selection	2522380
50520325	50520348	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	CATACCATTGCACTACAGCCTGG	PTPN1	ENSG00000196396	0.6803056250824391	[186,170]	[18,163]	5	dCas9-VP64	positive selection	2523311
50544802	50544825	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACTAGCCTGGCCAACACAG	PTPN1	ENSG00000196396	-0.8374586120276372	[108,300]	[27,44]	-7	dCas9-VP64	positive selection	2554178
50568446	50568469	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTCATGCTCAACAGAGTGATGG	PTPN1	ENSG00000196396	0.18284636297876553	[4,4]	[3,4]	4	hSpCas9	positive selection	3014684
50578598	50578621	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	0.08452649646953325	[3,3]	[2,3]	1	hSpCas9	positive selection	3014685
50568419	50568442	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	0.11278704252211054	[3,3]	[3,3]	2	hSpCas9	positive selection	3014686
50568420	50568443	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGTGGGAGCAGAAAAGCAGGGG	PTPN1	ENSG00000196396	-0.14786579947610345	[2,2]	[3,0]	-2	hSpCas9	positive selection	3014687
50568446	50568469	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTCATGCTCAACAGAGTGATGG	PTPN1	ENSG00000196396	0.4334117651681236	[4,4]	[6,2]	7	hSpCas9	positive selection	3082542
50578598	50578621	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	-0.03264155017630151	[3,3]	[1,2]	0	hSpCas9	positive selection	3082543
50568419	50568442	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	0.2896479053734491	[3,3]	[3,2]	5	hSpCas9	positive selection	3082544
50568420	50568443	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGTGGGAGCAGAAAAGCAGGGG	PTPN1	ENSG00000196396	0.6638658296360345	[2,2]	[2,3]	9	hSpCas9	positive selection	3082545
50564973	50564996		-	24336571	A375	resistance to PLX after 7 days	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.09599159123597534	[6,7]	[5,6]	-3	hSpCas9	positive selection	3138769
50564960	50564983		+	24336571	A375	resistance to PLX after 7 days	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.14833668133395794	[14,11]	[14,14]	5	hSpCas9	positive selection	3138770
50510546	50510569		+	24336571	A375	resistance to PLX after 7 days	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	-0.13791271625319668	[26,23]	[19,24]	-4	hSpCas9	positive selection	3138771
50564973	50564996		-	24336571	A375	resistance to PLX after 14 days	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	0.45594818823227	[4,4]	[2,2]	4	hSpCas9	positive selection	3196562
50564960	50564983		+	24336571	A375	resistance to PLX after 14 days	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.8389182850758607	[12,11]	[8,11]	7	hSpCas9	positive selection	3196563
50510546	50510569		+	24336571	A375	resistance to PLX after 14 days	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.20501812131448505	[17,18]	[9,9]	2	hSpCas9	positive selection	3196564
50564973	50564996		-	24336571	A375	viability after 7 days	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.30627467826600197	[8]	[6,7]	-4	hSpCas9	negative selection	3254355
50564960	50564983		+	24336571	A375	viability after 7 days	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.38895036324124777	[10]	[14,11]	6	hSpCas9	negative selection	3254356
50510546	50510569		+	24336571	A375	viability after 7 days	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.29275817835489015	[20]	[26,23]	4	hSpCas9	negative selection	3254357
50564973	50564996		-	24336571	A375	viability after 14 days	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.738779980978156	[8]	[4,4]	-7	hSpCas9	negative selection	3312148
50564960	50564983		+	24336571	A375	viability after 14 days	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.24818003868216174	[10]	[12,11]	3	hSpCas9	negative selection	3312149
50510546	50510569		+	24336571	A375	viability after 14 days	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	-0.10482615073422719	[20]	[17,18]	-1	hSpCas9	negative selection	3312150
50561425	50561448	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	-2.408009705739341	[811,811]	[0,0]	-9	hSpCas9	positive selection	3388247
50568389	50568412	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-1.3792984090978138	[397,397]	[0,0]	-8	hSpCas9	positive selection	3388248
50564960	50564983	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	-0.01879819382840228	[154,154]	[0,0]	0	hSpCas9	positive selection	3388249
50568445	50568468	20	+	26780180	HT29	viability (Avana library 4 designs)	CGTCATGCTCAACAGAGTGATGG	PTPN1	ENSG00000196396	-0.343964453048088	[]	[]	-5	hSpCas9	negative selection	3452928
50578598	50578621	20	-	26780180	HT29	viability (Avana library 4 designs)	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	2.34617179646754	[]	[]	8	hSpCas9	negative selection	3452929
50568418	50568441	20	+	26780180	HT29	viability (Avana library 4 designs)	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	0.908503288817613	[]	[]	3	hSpCas9	negative selection	3452930
50568419	50568442	20	+	26780180	HT29	viability (Avana library 4 designs)	GTGTGGGAGCAGAAAAGCAGGGG	PTPN1	ENSG00000196396	3.76387189101352	[]	[]	9	hSpCas9	negative selection	3452931
50568419	50568442	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTGTGGGAGCAGAAAAGCAGGGG	PTPN1	ENSG00000196396	-6.43953150510216	[]	[]	-6	hSpCas9	negative selection	3549539
50568418	50568441	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	-1.79854703571221	[]	[]	-2	hSpCas9	negative selection	3549540
50568445	50568468	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGTCATGCTCAACAGAGTGATGG	PTPN1	ENSG00000196396	-1.73739252224901	[]	[]	-2	hSpCas9	negative selection	3549541
50578598	50578621	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	-2.16531149156162	[]	[]	-3	hSpCas9	negative selection	3549542
50579185	50579208	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTGATATCAACGGAAGAAGGG	PTPN1	ENSG00000196396	-4.29483051930506	[]	[]	-5	hSpCas9	negative selection	3549543
50578442	50578465	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	TACATTTCCACTATACCACATGG	PTPN1	ENSG00000196396	-11.758306561427	[]	[]	-8	hSpCas9	negative selection	3549544
50568419	50568442	20	+	26780180	A375	viability (Avana lentiGuide)	GTGTGGGAGCAGAAAAGCAGGGG	PTPN1	ENSG00000196396	18.0897587448825	[]	[]	8	hSpCas9	negative selection	3658198
50568418	50568441	20	+	26780180	A375	viability (Avana lentiGuide)	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	7.07193130525398	[]	[]	5	hSpCas9	negative selection	3658199
50568445	50568468	20	+	26780180	A375	viability (Avana lentiGuide)	CGTCATGCTCAACAGAGTGATGG	PTPN1	ENSG00000196396	11.7530104215186	[]	[]	7	hSpCas9	negative selection	3658200
50578598	50578621	20	-	26780180	A375	viability (Avana lentiGuide)	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	8.54398416629559	[]	[]	6	hSpCas9	negative selection	3658201
50579185	50579208	20	-	26780180	A375	viability (Avana lentiGuide)	TCTTGATATCAACGGAAGAAGGG	PTPN1	ENSG00000196396	3.49312800041734	[]	[]	3	hSpCas9	negative selection	3658202
50578442	50578465	20	+	26780180	A375	viability (Avana lentiGuide)	TACATTTCCACTATACCACATGG	PTPN1	ENSG00000196396	8.9959847347028	[]	[]	6	hSpCas9	negative selection	3658203
50568419	50568442	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGTGGGAGCAGAAAAGCAGGGG	PTPN1	ENSG00000196396	-0.6072237562276869	[4]	[2,2]	-7	hSpCas9	positive selection	3766805
50568418	50568441	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	-0.8203335382040338	[4]	[4,0]	-8	hSpCas9	positive selection	3766806
50568445	50568468	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTCATGCTCAACAGAGTGATGG	PTPN1	ENSG00000196396	-0.21039403035994342	[5]	[6,3]	-3	hSpCas9	positive selection	3766807
50578598	50578621	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	-0.20866556112292683	[4]	[3,3]	-3	hSpCas9	positive selection	3766808
50579185	50579208	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTGATATCAACGGAAGAAGGG	PTPN1	ENSG00000196396	-0.4300293808005236	[6]	[4,4]	-6	hSpCas9	positive selection	3766809
50578442	50578465	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TACATTTCCACTATACCACATGG	PTPN1	ENSG00000196396	-0.5237309954049926	[8]	[5,5]	-6	hSpCas9	positive selection	3766810
50568419	50568442	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGTGGGAGCAGAAAAGCAGGGG	PTPN1	ENSG00000196396	-0.7472309073293079	[5]	[0,4]	-7	hSpCas9	positive selection	3875412
50568418	50568441	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	-0.7783859734033365	[5]	[2,2]	-7	hSpCas9	positive selection	3875413
50568445	50568468	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTCATGCTCAACAGAGTGATGG	PTPN1	ENSG00000196396	-0.19896775259609809	[6]	[4,4]	-3	hSpCas9	positive selection	3875414
50578598	50578621	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	-0.8692862094027904	[4]	[1,1]	-8	hSpCas9	positive selection	3875415
50579185	50579208	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTGATATCAACGGAAGAAGGG	PTPN1	ENSG00000196396	-0.07840500784089885	[5]	[5,3]	-1	hSpCas9	positive selection	3875416
50578442	50578465	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TACATTTCCACTATACCACATGG	PTPN1	ENSG00000196396	0.003561487864774726	[7]	[6,6]	0	hSpCas9	positive selection	3875417
50568389	50568412	20	-	26780180	A375	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.774914663254545	[]	[]	3	hSpCas9	negative selection	3985831
50510569	50510592	20	+	26780180	A375	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	1.03866258639834	[]	[]	5	hSpCas9	negative selection	3985832
50564973	50564996	20	-	26780180	A375	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	1.71874622442261	[]	[]	9	hSpCas9	negative selection	3985833
50564960	50564983	20	+	26780180	A375	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	1.08992822087498	[]	[]	5	hSpCas9	negative selection	3985834
50561425	50561448	20	-	26780180	A375	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.76139322881425	[]	[]	3	hSpCas9	negative selection	3985835
50510546	50510569	20	+	26780180	A375	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	1.79455351836609	[]	[]	9	hSpCas9	negative selection	3985836
50568389	50568412	20	-	26780180	HT29	viability (GeCKOv2 library)	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.638783279647873	[]	[]	2	hSpCas9	negative selection	4093797
50510569	50510592	20	+	26780180	HT29	viability (GeCKOv2 library)	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.830593272510601	[]	[]	3	hSpCas9	negative selection	4093798
50564973	50564996	20	-	26780180	HT29	viability (GeCKOv2 library)	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	1.04917665067445	[]	[]	5	hSpCas9	negative selection	4093799
50564960	50564983	20	+	26780180	HT29	viability (GeCKOv2 library)	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	1.27235048857826	[]	[]	6	hSpCas9	negative selection	4093800
50561425	50561448	20	-	26780180	HT29	viability (GeCKOv2 library)	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.605762657397093	[]	[]	2	hSpCas9	negative selection	4093801
50510546	50510569	20	+	26780180	HT29	viability (GeCKOv2 library)	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	1.7655343124669	[]	[]	8	hSpCas9	negative selection	4093802
50564973	50564996	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.16244713210870765	[2]	[1,1]	-4	hSpCas9	positive selection	4164050
50564960	50564983	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.43937089102210103	[3]	[2,3]	8	hSpCas9	positive selection	4164051
50510546	50510569	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.17675323518519245	[3]	[2,3]	4	hSpCas9	positive selection	4164052
50564973	50564996	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.036221060465622845	[2]	[2,0,0,0]	0	hSpCas9	positive selection	4228072
50564960	50564983	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	1.3936676012181421	[2]	[1,0,0,4]	9	hSpCas9	positive selection	4228073
50510546	50510569	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.7057694685046392	[4]	[1,2,2,3]	4	hSpCas9	positive selection	4228074
50510546	50510569	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	-0.05223195336450043	[3]	[2,2]	-1	hSpCas9	positive selection	4293062
50564973	50564996	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.2631064465733032	[2]	[2,0]	-5	hSpCas9	positive selection	4293063
50510569	50510592	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	-0.11641472299915881	[2]	[2,0]	-2	hSpCas9	positive selection	4293064
50561425	50561448	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.23487134608457694	[4]	[4,4]	5	hSpCas9	positive selection	4357321
50568389	50568412	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.14167736349943838	[3]	[3,2]	3	hSpCas9	positive selection	4357322
50564960	50564983	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.00024426145236783325	[2]	[2,1]	0	hSpCas9	positive selection	4357323
50578512	50578534	20	+	27760321	OCIAML3	viability	TTTCAAAGTCCGAGAGTCAGGG	PTPN1	ENSG00000196396	0.3240969877378825	[348,339]	[334,341]	4	hSpCas9	negative selection	4431864
50578533	50578555	20	+	27760321	OCIAML3	viability	GTCACTCAGCCCGGAGCACGGG	PTPN1	ENSG00000196396	0.3010860779052015	[787,612]	[714,611]	3	hSpCas9	negative selection	4431865
50579219	50579241	20	+	27760321	OCIAML3	viability	GAAATGAGGAAGTTTCGGATGG	PTPN1	ENSG00000196396	0.4859768859967051	[517,458]	[508,566]	6	hSpCas9	negative selection	4431866
50578512	50578534	20	+	27760321	OCIAML2	viability	TTTCAAAGTCCGAGAGTCAGGG	PTPN1	ENSG00000196396	0.9857782980322258	[348,339]	[575,522]	9	hSpCas9	negative selection	4515327
50578533	50578555	20	+	27760321	OCIAML2	viability	GTCACTCAGCCCGGAGCACGGG	PTPN1	ENSG00000196396	0.12117936463929313	[787,612]	[564,673]	1	hSpCas9	negative selection	4515328
50579219	50579241	20	+	27760321	OCIAML2	viability	GAAATGAGGAAGTTTCGGATGG	PTPN1	ENSG00000196396	0.2747919364404007	[517,458]	[371,615]	3	hSpCas9	negative selection	4515329
50578512	50578534	20	+	27760321	MV411	viability	TTTCAAAGTCCGAGAGTCAGGG	PTPN1	ENSG00000196396	1.5476135650581568	[348,339]	[723,578]	9	hSpCas9	negative selection	4598790
50578533	50578555	20	+	27760321	MV411	viability	GTCACTCAGCCCGGAGCACGGG	PTPN1	ENSG00000196396	1.5070644824578259	[787,612]	[1221,1428]	9	hSpCas9	negative selection	4598791
50579219	50579241	20	+	27760321	MV411	viability	GAAATGAGGAAGTTTCGGATGG	PTPN1	ENSG00000196396	1.5080905617406168	[517,458]	[878,969]	9	hSpCas9	negative selection	4598792
50578512	50578534	20	+	27760321	HL60	viability	TTTCAAAGTCCGAGAGTCAGGG	PTPN1	ENSG00000196396	0.6579359514504045	[348,339]	[411,479]	7	hSpCas9	negative selection	4682253
50578533	50578555	20	+	27760321	HL60	viability	GTCACTCAGCCCGGAGCACGGG	PTPN1	ENSG00000196396	0.16375457657116232	[787,612]	[587,687]	2	hSpCas9	negative selection	4682254
50579219	50579241	20	+	27760321	HL60	viability	GAAATGAGGAAGTTTCGGATGG	PTPN1	ENSG00000196396	0.1422987180890576	[517,458]	[345,538]	1	hSpCas9	negative selection	4682255
50578512	50578534	20	+	27760321	HT1080	viability	TTTCAAAGTCCGAGAGTCAGGG	PTPN1	ENSG00000196396	-1.3095062452375918	[339,265]	[31,66]	-5	hSpCas9	negative selection	4765716
50578533	50578555	20	+	27760321	HT1080	viability	GTCACTCAGCCCGGAGCACGGG	PTPN1	ENSG00000196396	-1.8619319543904571	[612,478]	[45,74]	-6	hSpCas9	negative selection	4765717
50579219	50579241	20	+	27760321	HT1080	viability	GAAATGAGGAAGTTTCGGATGG	PTPN1	ENSG00000196396	-1.2483951730140945	[458,357]	[99,33]	-5	hSpCas9	negative selection	4765718
50578512	50578534	20	+	27760321	HT29	viability after 7 days	TTTCAAAGTCCGAGAGTCAGGG	PTPN1	ENSG00000196396	0.48640785790289554	[339,265]	[472,531,618]	7	hSpCas9	negative selection	4849179
50578533	50578555	20	+	27760321	HT29	viability after 7 days	GTCACTCAGCCCGGAGCACGGG	PTPN1	ENSG00000196396	0.3751065896414737	[612,478]	[845,772,1095]	6	hSpCas9	negative selection	4849180
50579219	50579241	20	+	27760321	HT29	viability after 7 days	GAAATGAGGAAGTTTCGGATGG	PTPN1	ENSG00000196396	-0.3564258389711772	[458,357]	[532,380,335]	-5	hSpCas9	negative selection	4849181
50578512	50578534	20	+	27760321	HT29	viability after 25 days	TTTCAAAGTCCGAGAGTCAGGG	PTPN1	ENSG00000196396	0.6881754483778735	[339,265]	[620,431,622]	7	hSpCas9	negative selection	4932642
50578533	50578555	20	+	27760321	HT29	viability after 25 days	GTCACTCAGCCCGGAGCACGGG	PTPN1	ENSG00000196396	1.076517252334809	[612,478]	[1019,1350,1625]	9	hSpCas9	negative selection	4932643
50579219	50579241	20	+	27760321	HT29	viability after 25 days	GAAATGAGGAAGTTTCGGATGG	PTPN1	ENSG00000196396	-0.009871306104995814	[458,357]	[536,415,428]	0	hSpCas9	negative selection	4932644
50578512	50578534	20	+	27760321	HT29	viability after 22 days	TTTCAAAGTCCGAGAGTCAGGG	PTPN1	ENSG00000196396	0.8170571492432964	[339,265]	[736,745,362]	8	hSpCas9	negative selection	5016105
50578533	50578555	20	+	27760321	HT29	viability after 22 days	GTCACTCAGCCCGGAGCACGGG	PTPN1	ENSG00000196396	0.6871510068592678	[612,478]	[733,1067,1256]	7	hSpCas9	negative selection	5016106
50579219	50579241	20	+	27760321	HT29	viability after 22 days	GAAATGAGGAAGTTTCGGATGG	PTPN1	ENSG00000196396	-0.25059115348168753	[458,357]	[544,325,314]	-3	hSpCas9	negative selection	5016107
50578512	50578534	20	+	27760321	HT29	viability after 19 days	TTTCAAAGTCCGAGAGTCAGGG	PTPN1	ENSG00000196396	0.5181623684294239	[339,265]	[471,512,500]	5	hSpCas9	negative selection	5099568
50578533	50578555	20	+	27760321	HT29	viability after 19 days	GTCACTCAGCCCGGAGCACGGG	PTPN1	ENSG00000196396	0.7045499002995866	[612,478]	[683,1061,1261]	7	hSpCas9	negative selection	5099569
50579219	50579241	20	+	27760321	HT29	viability after 19 days	GAAATGAGGAAGTTTCGGATGG	PTPN1	ENSG00000196396	-0.3902503835838901	[458,357]	[616,192,288]	-4	hSpCas9	negative selection	5099570
50578512	50578534	20	+	27760321	HT29	viability after 16 days	TTTCAAAGTCCGAGAGTCAGGG	PTPN1	ENSG00000196396	0.49924938590823287	[339,265]	[525,442,473]	6	hSpCas9	negative selection	5183031
50578533	50578555	20	+	27760321	HT29	viability after 16 days	GTCACTCAGCCCGGAGCACGGG	PTPN1	ENSG00000196396	0.7423391466276007	[612,478]	[1338,973,783]	8	hSpCas9	negative selection	5183032
50579219	50579241	20	+	27760321	HT29	viability after 16 days	GAAATGAGGAAGTTTCGGATGG	PTPN1	ENSG00000196396	0.07178563720662873	[458,357]	[509,430,503]	0	hSpCas9	negative selection	5183033
50578512	50578534	20	+	27760321	HT29	viability after 13 days	TTTCAAAGTCCGAGAGTCAGGG	PTPN1	ENSG00000196396	0.5298104418059985	[339,265]	[771,378,378]	6	hSpCas9	negative selection	5266494
50578533	50578555	20	+	27760321	HT29	viability after 13 days	GTCACTCAGCCCGGAGCACGGG	PTPN1	ENSG00000196396	0.46911148662233126	[612,478]	[731,939,953]	6	hSpCas9	negative selection	5266495
50579219	50579241	20	+	27760321	HT29	viability after 13 days	GAAATGAGGAAGTTTCGGATGG	PTPN1	ENSG00000196396	-0.06929900667148796	[458,357]	[327,401,614]	-1	hSpCas9	negative selection	5266496
50578512	50578534	20	+	27760321	HT29	viability after 10 days	TTTCAAAGTCCGAGAGTCAGGG	PTPN1	ENSG00000196396	0.4613481453099125	[339,265]	[692,548,325]	6	hSpCas9	negative selection	5349957
50578533	50578555	20	+	27760321	HT29	viability after 10 days	GTCACTCAGCCCGGAGCACGGG	PTPN1	ENSG00000196396	0.29144736844432284	[612,478]	[948,922,637]	4	hSpCas9	negative selection	5349958
50579219	50579241	20	+	27760321	HT29	viability after 10 days	GAAATGAGGAAGTTTCGGATGG	PTPN1	ENSG00000196396	0.09687488948059753	[458,357]	[502,559,572]	1	hSpCas9	negative selection	5349959
50578512	50578534	20	+	27760321	MOLM13	viability	TTTCAAAGTCCGAGAGTCAGGG	PTPN1	ENSG00000196396	1.8496017148178594	[348,339]	[761,650]	9	hSpCas9	negative selection	5433420
50578533	50578555	20	+	27760321	MOLM13	viability	GTCACTCAGCCCGGAGCACGGG	PTPN1	ENSG00000196396	2.155759670778131	[787,612]	[2046,1494]	9	hSpCas9	negative selection	5433421
50579219	50579241	20	+	27760321	MOLM13	viability	GAAATGAGGAAGTTTCGGATGG	PTPN1	ENSG00000196396	2.4371419528984517	[517,458]	[1111,1811]	9	hSpCas9	negative selection	5433422
50510348	50510371	20	+	27661255	K562	viability	GCAGGCGTGATGCGTAGTTCCGG	PTPN1	ENSG00000196396	0.5289845042184473	[118,86]	[120,117]	9	dCas9-KRAB	negative selection	5505211
50510406	50510429	20	+	27661255	K562	viability	GCGGCGGTAGCTGCAGGGGTCGG	PTPN1	ENSG00000196396	0.028213005162825322	[52,135]	[51,95]	0	dCas9-KRAB	negative selection	5505212
50510454	50510477	20	+	27661255	K562	viability	GAGCGCGACGCGGCCTAGAGCGG	PTPN1	ENSG00000196396	0.026806978659466685	[1184,1322]	[1079,965]	0	dCas9-KRAB	negative selection	5505213
50510569	50510592	20	+	27661255	K562	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.13098882844038864	[678,771]	[556,697]	4	dCas9-KRAB	negative selection	5505214
50510602	50510625	20	-	27661255	K562	viability	GAAGGGCCCGCCACGCTCCGGGG	PTPN1	ENSG00000196396	-0.04694662263224603	[1136,1333]	[971,935]	-2	dCas9-KRAB	negative selection	5505215
50510546	50510569	20	+	27260156	BXPC3	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.10065572707004189	[638]	[584,702,721,886]	2	hSpCas9	negative selection	5565522
50564973	50564996	20	-	27260156	BXPC3	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.4767039001505473	[361]	[229,252,312,299]	-8	hSpCas9	negative selection	5565523
50510569	50510592	20	+	27260156	BXPC3	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.43939472721899686	[330]	[399,571,479,416]	8	hSpCas9	negative selection	5565524
50561425	50561448	20	-	27260156	BXPC3	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.009342336765672199	[1691]	[1602,1594,1906,2073]	0	hSpCas9	negative selection	5629781
50568389	50568412	20	-	27260156	BXPC3	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.0343391610057161	[924]	[879,906,1037,1169]	0	hSpCas9	negative selection	5629782
50564960	50564983	20	+	27260156	BXPC3	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.5737940186283355	[303]	[363,412,508,639]	9	hSpCas9	negative selection	5629783
50510546	50510569	20	+	27260156	A673	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.18090936600281105	[638]	[982,746,884,878]	4	hSpCas9	negative selection	5686773
50564973	50564996	20	-	27260156	A673	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.41928881738950596	[361]	[400,236,308,365]	-8	hSpCas9	negative selection	5686774
50510569	50510592	20	+	27260156	A673	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.31485023919521943	[330]	[577,445,390,577]	7	hSpCas9	negative selection	5686775
50561425	50561448	20	-	27260156	A673	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	-0.016858577622522963	[1691]	[1897,2097,1848,2178]	0	hSpCas9	negative selection	5751032
50568389	50568412	20	-	27260156	A673	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.07863176611220979	[924]	[1140,1028,984,1061]	-2	hSpCas9	negative selection	5751033
50564960	50564983	20	+	27260156	A673	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.40237929815599804	[303]	[499,497,416,517]	8	hSpCas9	negative selection	5751034
50510546	50510569	20	+	27260156	A375	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.23625460258853093	[638]	[765,1013,972,788]	3	hSpCas9	negative selection	5808024
50564973	50564996	20	-	27260156	A375	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.9734940535314722	[361]	[282,91,245,221]	-8	hSpCas9	negative selection	5808025
50510569	50510592	20	+	27260156	A375	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.13406150681668538	[330]	[390,647,454,252]	2	hSpCas9	negative selection	5808026
50561425	50561448	20	-	27260156	A375	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	-0.23034402701842294	[1691]	[1648,2034,1565,1546]	-3	hSpCas9	negative selection	5872283
50568389	50568412	20	-	27260156	A375	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.23825303517650342	[924]	[1256,975,697,758]	-3	hSpCas9	negative selection	5872284
50564960	50564983	20	+	27260156	A375	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.4447492886467972	[303]	[546,662,441,323]	6	hSpCas9	negative selection	5872285
50510546	50510569	20	+	27260156	COLO741	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.16912136318482018	[638]	[961,978,821]	3	hSpCas9	negative selection	5929275
50564973	50564996	20	-	27260156	COLO741	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.07766624770442432	[361]	[318,448,528]	-2	hSpCas9	negative selection	5929276
50510569	50510592	20	+	27260156	COLO741	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.650995546466005	[330]	[839,621,551]	9	hSpCas9	negative selection	5929277
50561425	50561448	20	-	27260156	COLO741	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	-0.027113191849636786	[1691]	[2322,1990,2066]	0	hSpCas9	negative selection	5993534
50568389	50568412	20	-	27260156	COLO741	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.05698273924431818	[924]	[1391,1367,959]	1	hSpCas9	negative selection	5993535
50564960	50564983	20	+	27260156	COLO741	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.058602326829148454	[303]	[377,490,345]	1	hSpCas9	negative selection	5993536
50510546	50510569	20	+	27260156	CAL120	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.20723924722458364	[638]	[1277,791,740]	3	hSpCas9	negative selection	6050526
50564973	50564996	20	-	27260156	CAL120	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.36744045328249353	[361]	[613,221,252]	-5	hSpCas9	negative selection	6050527
50510569	50510592	20	+	27260156	CAL120	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.10601811659765081	[330]	[434,423,468]	1	hSpCas9	negative selection	6050528
50561425	50561448	20	-	27260156	CAL120	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.06786568940059312	[1691]	[2600,2199,1883]	1	hSpCas9	negative selection	6114785
50568389	50568412	20	-	27260156	CAL120	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.30245856669325033	[924]	[1522,1521,1231]	4	hSpCas9	negative selection	6114786
50564960	50564983	20	+	27260156	CAL120	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	-0.3836397459977745	[303]	[349,249,278]	-5	hSpCas9	negative selection	6114787
50510546	50510569	20	+	27260156	CADOES1	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.6263747573826965	[638]	[742,939,1276,701]	8	hSpCas9	negative selection	6171777
50564973	50564996	20	-	27260156	CADOES1	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.2334969482406799	[361]	[365,227,268,281]	-4	hSpCas9	negative selection	6171778
50510569	50510592	20	+	27260156	CADOES1	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.6216070984871384	[330]	[375,538,556,420]	8	hSpCas9	negative selection	6171779
50561425	50561448	20	-	27260156	CADOES1	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.22282026927806076	[1691]	[1663,2207,1693,1778]	4	hSpCas9	negative selection	6236036
50568389	50568412	20	-	27260156	CADOES1	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.24688716660205723	[924]	[1133,1077,706,1169]	4	hSpCas9	negative selection	6236037
50564960	50564983	20	+	27260156	CADOES1	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.2961516572266022	[303]	[359,316,403,305]	5	hSpCas9	negative selection	6236038
50510546	50510569	20	+	27260156	EWS502	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.05306388141136531	[638]	[527,741,832,725]	0	hSpCas9	negative selection	6293028
50564973	50564996	20	-	27260156	EWS502	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	0.04801211139471945	[361]	[429,443,350,348]	0	hSpCas9	negative selection	6293029
50510569	50510592	20	+	27260156	EWS502	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.16737956848978175	[330]	[396,353,334,494]	3	hSpCas9	negative selection	6293030
50561425	50561448	20	-	27260156	EWS502	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.1731406151067385	[1691]	[1624,2217,2172,2106]	3	hSpCas9	negative selection	6357287
50568389	50568412	20	-	27260156	EWS502	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.024669794141682466	[924]	[863,962,980,1059]	0	hSpCas9	negative selection	6357288
50564960	50564983	20	+	27260156	EWS502	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.550471657335322	[303]	[469,486,435,491]	8	hSpCas9	negative selection	6357289
50510546	50510569	20	+	27260156	EW8	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.2233403668407059	[638]	[819,617,465,559]	4	hSpCas9	negative selection	6414279
50564973	50564996	20	-	27260156	EW8	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.07074479751288193	[361]	[263,343,262,246]	-1	hSpCas9	negative selection	6414280
50510569	50510592	20	+	27260156	EW8	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.6114241949926104	[330]	[359,397,477,384]	9	hSpCas9	negative selection	6414281
50561425	50561448	20	-	27260156	EW8	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.22445138081816074	[1691]	[1796,1578,1615,1430]	4	hSpCas9	negative selection	6478538
50568389	50568412	20	-	27260156	EW8	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.27693685447464145	[924]	[1168,854,760,898]	5	hSpCas9	negative selection	6478539
50564960	50564983	20	+	27260156	EW8	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.28390156808333405	[303]	[280,416,231,278]	5	hSpCas9	negative selection	6478540
50510546	50510569	20	+	27260156	CORL105	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.18008296163578308	[638]	[723,835,914,920]	3	hSpCas9	negative selection	6535530
50564973	50564996	20	-	27260156	CORL105	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.026097072119042775	[361]	[399,371,611,311]	0	hSpCas9	negative selection	6535531
50510569	50510592	20	+	27260156	CORL105	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.24323672046642447	[330]	[421,382,550,492]	4	hSpCas9	negative selection	6535532
50561425	50561448	20	-	27260156	CORL105	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	-0.023671644788229695	[1691]	[2009,1710,2419,1733]	0	hSpCas9	negative selection	6599789
50568389	50568412	20	-	27260156	CORL105	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.13926420631484282	[924]	[962,947,1055,976]	-3	hSpCas9	negative selection	6599790
50564960	50564983	20	+	27260156	CORL105	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.374678918711905	[303]	[495,388,523,448]	7	hSpCas9	negative selection	6599791
50510546	50510569	20	+	27260156	HS294T	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.07363709215265168	[638]	[412,140,255,209]	1	hSpCas9	negative selection	6656781
50564973	50564996	20	-	27260156	HS294T	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-1.12692973707362	[361]	[50,41,81,86]	-9	hSpCas9	negative selection	6656782
50510569	50510592	20	+	27260156	HS294T	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.5269577327004469	[330]	[113,144,237,260]	7	hSpCas9	negative selection	6656783
50561425	50561448	20	-	27260156	HS294T	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.2686346230790888	[1691]	[797,820,663,879]	3	hSpCas9	negative selection	6721040
50568389	50568412	20	-	27260156	HS294T	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.3710445845842717	[924]	[388,550,488,415]	5	hSpCas9	negative selection	6721041
50564960	50564983	20	+	27260156	HS294T	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.5572591008440954	[303]	[184,131,243,121]	7	hSpCas9	negative selection	6721042
50510546	50510569	20	+	27260156	HCC44	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.46705458647303977	[638]	[1313,877,984,858]	7	hSpCas9	negative selection	6778032
50564973	50564996	20	-	27260156	HCC44	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.37242490562662967	[361]	[315,319,415,229]	-5	hSpCas9	negative selection	6778033
50510569	50510592	20	+	27260156	HCC44	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.6811473473939724	[330]	[522,823,533,468]	9	hSpCas9	negative selection	6778034
50561425	50561448	20	-	27260156	HCC44	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	-0.08474243682877791	[1691]	[1584,1783,2089,1776]	-1	hSpCas9	negative selection	6842291
50568389	50568412	20	-	27260156	HCC44	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.1340986808383252	[924]	[1055,859,973,941]	-2	hSpCas9	negative selection	6842292
50564960	50564983	20	+	27260156	HCC44	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	-0.04757313189940027	[303]	[335,363,281,332]	-1	hSpCas9	negative selection	6842293
50510546	50510569	20	+	27260156	G402	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.49304742764816756	[638]	[1543,841,1059,993]	6	hSpCas9	negative selection	6899283
50564973	50564996	20	-	27260156	G402	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	0.15933897052390647	[361]	[329,746,361,521]	2	hSpCas9	negative selection	6899284
50510569	50510592	20	+	27260156	G402	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.5624703011012716	[330]	[531,589,658,592]	7	hSpCas9	negative selection	6899285
50561425	50561448	20	-	27260156	G402	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.4918445361030974	[1691]	[2869,2209,3280,3181]	6	hSpCas9	negative selection	6963542
50568389	50568412	20	-	27260156	G402	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.20645429890975542	[924]	[931,1893,1370,1002]	2	hSpCas9	negative selection	6963543
50564960	50564983	20	+	27260156	G402	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.5341788714429744	[303]	[769,424,638,348]	6	hSpCas9	negative selection	6963544
50510546	50510569	20	+	27260156	L33	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.3224901754906041	[638]	[724,378,571,639]	6	hSpCas9	negative selection	7020534
50564973	50564996	20	-	27260156	L33	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.17599884728866266	[361]	[285,147,201,313]	-4	hSpCas9	negative selection	7020535
50510569	50510592	20	+	27260156	L33	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.35244646547870695	[330]	[484,132,231,508]	7	hSpCas9	negative selection	7020536
50561425	50561448	20	-	27260156	L33	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	-0.05119831363341465	[1691]	[1591,706,959,1686]	-1	hSpCas9	negative selection	7084793
50568389	50568412	20	-	27260156	L33	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.034060609358718574	[924]	[836,384,554,954]	-1	hSpCas9	negative selection	7084794
50564960	50564983	20	+	27260156	L33	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.5342859734769632	[303]	[382,230,233,442]	9	hSpCas9	negative selection	7084795
50510546	50510569	20	+	27260156	K562	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	-0.07877221015101588	[638]	[422,651,358,689]	-1	hSpCas9	negative selection	7141785
50564973	50564996	20	-	27260156	K562	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-1.8992927736515333	[361]	[73,124,67,78]	-9	hSpCas9	negative selection	7141786
50510569	50510592	20	+	27260156	K562	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	-0.41137374040818486	[330]	[205,150,274,242]	-5	hSpCas9	negative selection	7141787
50561425	50561448	20	-	27260156	K562	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.14697964229416316	[1691]	[1664,1609,2187,1228]	1	hSpCas9	negative selection	7206044
50568389	50568412	20	-	27260156	K562	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.15671628473087507	[924]	[674,894,1000,412]	-2	hSpCas9	negative selection	7206045
50564960	50564983	20	+	27260156	K562	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.014590268530900952	[303]	[216,280,183,388]	0	hSpCas9	negative selection	7206046
50510546	50510569	20	+	27260156	HT29	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.1903715271138342	[638]	[962,1013,900,700]	3	hSpCas9	negative selection	7263036
50564973	50564996	20	-	27260156	HT29	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.1268929650781	[361]	[376,489,303,438]	-3	hSpCas9	negative selection	7263037
50510569	50510592	20	+	27260156	HT29	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.3023645066187229	[330]	[600,469,554,375]	6	hSpCas9	negative selection	7263038
50561425	50561448	20	-	27260156	HT29	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.13744434001729067	[1691]	[2275,2608,2150,2053]	2	hSpCas9	negative selection	7327295
50568389	50568412	20	-	27260156	HT29	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.05612172171185337	[924]	[1373,1103,1202,1015]	1	hSpCas9	negative selection	7327296
50564960	50564983	20	+	27260156	HT29	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.371238845980842	[303]	[560,612,422,345]	7	hSpCas9	negative selection	7327297
50510546	50510569	20	+	27260156	MHHES1	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.15566943966623348	[638]	[715,816,973,697]	3	hSpCas9	negative selection	7384287
50564973	50564996	20	-	27260156	MHHES1	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	0.13625051997602017	[361]	[485,509,377,423]	2	hSpCas9	negative selection	7384288
50510569	50510592	20	+	27260156	MHHES1	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.4112110862921214	[330]	[505,482,550,443]	7	hSpCas9	negative selection	7384289
50561425	50561448	20	-	27260156	MHHES1	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.10572394361794846	[1691]	[2494,2043,2032,1714]	2	hSpCas9	negative selection	7448546
50568389	50568412	20	-	27260156	MHHES1	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.009468967886063662	[924]	[1303,1134,858,892]	0	hSpCas9	negative selection	7448547
50564960	50564983	20	+	27260156	MHHES1	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.3480590307789861	[303]	[437,482,432,393]	6	hSpCas9	negative selection	7448548
50510546	50510569	20	+	27260156	MEWO	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.16628113591227156	[638]	[991,390,692]	3	hSpCas9	negative selection	7505538
50564973	50564996	20	-	27260156	MEWO	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.4095659533411996	[361]	[230,297,230]	-7	hSpCas9	negative selection	7505539
50510569	50510592	20	+	27260156	MEWO	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.4578287859361567	[330]	[624,335,353]	8	hSpCas9	negative selection	7505540
50561425	50561448	20	-	27260156	MEWO	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	-0.1211670656681254	[1691]	[1532,1466,1380]	-3	hSpCas9	negative selection	7569797
50568389	50568412	20	-	27260156	MEWO	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.044519287465683455	[924]	[951,834,751]	-1	hSpCas9	negative selection	7569798
50564960	50564983	20	+	27260156	MEWO	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.2961728976201186	[303]	[382,376,293]	6	hSpCas9	negative selection	7569799
50510546	50510569	20	+	27260156	LNCAPCLONEFGC	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.34633507275652087	[638]	[856,656,742,689]	5	hSpCas9	negative selection	7626789
50564973	50564996	20	-	27260156	LNCAPCLONEFGC	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.503005974795303	[361]	[246,207,226,243]	-6	hSpCas9	negative selection	7626790
50510569	50510592	20	+	27260156	LNCAPCLONEFGC	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.43934148372338855	[330]	[392,364,439,435]	7	hSpCas9	negative selection	7626791
50561425	50561448	20	-	27260156	LNCAPCLONEFGC	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.24672411883524603	[1691]	[1691,1751,1926,1924]	4	hSpCas9	negative selection	7691048
50568389	50568412	20	-	27260156	LNCAPCLONEFGC	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.30034883567010506	[924]	[911,940,1179,1123]	5	hSpCas9	negative selection	7691049
50564960	50564983	20	+	27260156	LNCAPCLONEFGC	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.2280425111594665	[303]	[236,389,260,389]	3	hSpCas9	negative selection	7691050
50510546	50510569	20	+	27260156	PANC0327	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.10251797815614316	[638]	[699,571,680,496]	1	hSpCas9	negative selection	7748040
50564973	50564996	20	-	27260156	PANC0327	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.7791972141623231	[361]	[174,166,172,235]	-8	hSpCas9	negative selection	7748041
50510569	50510592	20	+	27260156	PANC0327	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	-0.15299053782588312	[330]	[331,225,171,337]	-2	hSpCas9	negative selection	7748042
50561425	50561448	20	-	27260156	PANC0327	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.11682182929990503	[1691]	[1483,1922,1637,1423]	1	hSpCas9	negative selection	7812299
50568389	50568412	20	-	27260156	PANC0327	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.037230433485320735	[924]	[859,663,930,941]	0	hSpCas9	negative selection	7812300
50564960	50564983	20	+	27260156	PANC0327	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.3145816409751241	[303]	[336,192,463,367]	5	hSpCas9	negative selection	7812301
50510546	50510569	20	+	27260156	NCIH2009	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.09661904840664359	[638]	[1054,793,1035]	1	hSpCas9	negative selection	7869291
50564973	50564996	20	-	27260156	NCIH2009	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.16487073055846035	[361]	[515,423,425]	-2	hSpCas9	negative selection	7869292
50510569	50510592	20	+	27260156	NCIH2009	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.38229123938622095	[330]	[661,602,553]	5	hSpCas9	negative selection	7869293
50561425	50561448	20	-	27260156	NCIH2009	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.12305779618290336	[1691]	[3255,2396,2203]	1	hSpCas9	negative selection	7933550
50568389	50568412	20	-	27260156	NCIH2009	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.02763326531393495	[924]	[1527,1202,1122]	0	hSpCas9	negative selection	7933551
50564960	50564983	20	+	27260156	NCIH2009	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.680625514204289	[303]	[580,485,957]	8	hSpCas9	negative selection	7933552
50510546	50510569	20	+	27260156	NCIH1373	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.2862770398889741	[638]	[761,810,921,259]	3	hSpCas9	negative selection	7990542
50564973	50564996	20	-	27260156	NCIH1373	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	0.06423146560228626	[361]	[677,321,219,140]	0	hSpCas9	negative selection	7990543
50510569	50510592	20	+	27260156	NCIH1373	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.6222672392947104	[330]	[579,431,641,169]	6	hSpCas9	negative selection	7990544
50561425	50561448	20	-	27260156	NCIH1373	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.4491827270043496	[1691]	[2764,1809,2563,883]	4	hSpCas9	negative selection	8054801
50568389	50568412	20	-	27260156	NCIH1373	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.694669116616652	[924]	[2577,1573,1447,323]	7	hSpCas9	negative selection	8054802
50564960	50564983	20	+	27260156	NCIH1373	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.8207559375008792	[303]	[486,473,440,269]	7	hSpCas9	negative selection	8054803
50510546	50510569	20	+	27260156	PATU8902	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.578275085854248	[638]	[1294,1162,1035,1961]	6	hSpCas9	negative selection	8111793
50564973	50564996	20	-	27260156	PATU8902	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-1.3939059851916682	[361]	[56,240,243,214]	-8	hSpCas9	negative selection	8111794
50510569	50510592	20	+	27260156	PATU8902	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.9413528023933216	[330]	[817,1358,711,665]	8	hSpCas9	negative selection	8111795
50561425	50561448	20	-	27260156	PATU8902	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.6367552900574673	[1691]	[3092,4404,3591,3550]	6	hSpCas9	negative selection	8176052
50568389	50568412	20	-	27260156	PATU8902	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.18926634708533718	[924]	[1441,1501,952,2186]	2	hSpCas9	negative selection	8176053
50564960	50564983	20	+	27260156	PATU8902	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.720749923883448	[303]	[667,676,701,742]	7	hSpCas9	negative selection	8176054
50510546	50510569	20	+	27260156	PANC1	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.35860182969665766	[638]	[631,898,708,618]	6	hSpCas9	negative selection	8233044
50564973	50564996	20	-	27260156	PANC1	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	0.19180994866239529	[361]	[267,599,322,286]	3	hSpCas9	negative selection	8233045
50510569	50510592	20	+	27260156	PANC1	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.3377765689597019	[330]	[342,516,296,313]	5	hSpCas9	negative selection	8233046
50561425	50561448	20	-	27260156	PANC1	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	-0.021590596866725376	[1691]	[1508,1504,1337,1372]	0	hSpCas9	negative selection	8297303
50568389	50568412	20	-	27260156	PANC1	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.00020505027640171924	[924]	[777,876,903,647]	0	hSpCas9	negative selection	8297304
50564960	50564983	20	+	27260156	PANC1	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.036453486046207906	[303]	[367,309,205,199]	0	hSpCas9	negative selection	8297305
50510546	50510569	20	+	27260156	PANC0813	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.2510897461701833	[638]	[1032,807,859,883]	4	hSpCas9	negative selection	8354295
50564973	50564996	20	-	27260156	PANC0813	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.44214110772258053	[361]	[389,320,351,201]	-6	hSpCas9	negative selection	8354296
50510569	50510592	20	+	27260156	PANC0813	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.39254386330063407	[330]	[500,446,680,416]	6	hSpCas9	negative selection	8354297
50561425	50561448	20	-	27260156	PANC0813	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	-0.06840583452403837	[1691]	[2172,2002,1556,1870]	-1	hSpCas9	negative selection	8418554
50568389	50568412	20	-	27260156	PANC0813	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.05596651261860941	[924]	[1009,1077,1097,992]	-1	hSpCas9	negative selection	8418555
50564960	50564983	20	+	27260156	PANC0813	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.49137444073988007	[303]	[518,485,437,561]	7	hSpCas9	negative selection	8418556
50510546	50510569	20	+	27260156	RDES	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.28945462320099113	[638]	[725,696,1081,1165]	4	hSpCas9	negative selection	8475546
50564973	50564996	20	-	27260156	RDES	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.23310443719130614	[361]	[272,507,251,373]	-4	hSpCas9	negative selection	8475547
50510569	50510592	20	+	27260156	RDES	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.7100968110311587	[330]	[471,612,650,797]	9	hSpCas9	negative selection	8475548
50561425	50561448	20	-	27260156	RDES	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.3303611328782239	[1691]	[2039,2153,2870,2838]	5	hSpCas9	negative selection	8539805
50568389	50568412	20	-	27260156	RDES	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.17915100654377747	[924]	[985,1034,1477,1383]	3	hSpCas9	negative selection	8539806
50564960	50564983	20	+	27260156	RDES	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.4822274749883305	[303]	[337,423,549,701]	7	hSpCas9	negative selection	8539807
50510546	50510569	20	+	27260156	PC3	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.028782128770729942	[638]	[407,809,824,655]	0	hSpCas9	negative selection	8596797
50564973	50564996	20	-	27260156	PC3	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.2718419698619673	[361]	[214,307,406,310]	-6	hSpCas9	negative selection	8596798
50510569	50510592	20	+	27260156	PC3	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.5064329839027842	[330]	[418,278,502,665]	9	hSpCas9	negative selection	8596799
50561425	50561448	20	-	27260156	PC3	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	-0.058068585560268726	[1691]	[992,1610,2728,1702]	-1	hSpCas9	negative selection	8661056
50568389	50568412	20	-	27260156	PC3	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.32220146268884287	[924]	[542,738,1043,744]	-6	hSpCas9	negative selection	8661057
50564960	50564983	20	+	27260156	PC3	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.05462120381817015	[303]	[197,344,502,303]	1	hSpCas9	negative selection	8661058
50510546	50510569	20	+	27260156	PATU8988T	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.30187616848898224	[638]	[837,774,712,716]	5	hSpCas9	negative selection	8718048
50564973	50564996	20	-	27260156	PATU8988T	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.3169882455318993	[361]	[201,364,331,226]	-5	hSpCas9	negative selection	8718049
50510569	50510592	20	+	27260156	PATU8988T	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.3341775808419085	[330]	[271,338,405,605]	6	hSpCas9	negative selection	8718050
50561425	50561448	20	-	27260156	PATU8988T	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.093031026019891	[1691]	[1409,1960,1845,1779]	1	hSpCas9	negative selection	8782307
50568389	50568412	20	-	27260156	PATU8988T	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.03837977574890317	[924]	[850,947,866,1016]	0	hSpCas9	negative selection	8782308
50564960	50564983	20	+	27260156	PATU8988T	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.43402377116210344	[303]	[413,614,240,334]	7	hSpCas9	negative selection	8782309
50510546	50510569	20	+	27260156	T47D	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.19585272341969762	[638]	[828,783,963,836]	4	hSpCas9	negative selection	8839299
50564973	50564996	20	-	27260156	T47D	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.38139471909788003	[361]	[316,278,396,303]	-7	hSpCas9	negative selection	8839300
50510569	50510592	20	+	27260156	T47D	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.2641522955958132	[330]	[541,370,427,521]	5	hSpCas9	negative selection	8839301
50561425	50561448	20	-	27260156	T47D	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.07695985260998062	[1691]	[1897,2120,2016,2282]	1	hSpCas9	negative selection	8903558
50568389	50568412	20	-	27260156	T47D	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.00850163645932489	[924]	[1115,913,1175,1144]	0	hSpCas9	negative selection	8903559
50564960	50564983	20	+	27260156	T47D	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.5693988593297005	[303]	[469,518,572,539]	9	hSpCas9	negative selection	8903560
50510546	50510569	20	+	27260156	SU8686	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.3251236418490807	[638]	[585,962,842,776]	5	hSpCas9	negative selection	8960550
50564973	50564996	20	-	27260156	SU8686	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.634184595100489	[361]	[171,235,198,338]	-7	hSpCas9	negative selection	8960551
50510569	50510592	20	+	27260156	SU8686	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.10428730360709237	[330]	[299,460,311,320]	1	hSpCas9	negative selection	8960552
50561425	50561448	20	-	27260156	SU8686	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.10424728052600485	[1691]	[1882,1520,1833,2025]	1	hSpCas9	negative selection	9024809
50568389	50568412	20	-	27260156	SU8686	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.11839295461021482	[924]	[966,708,900,1520]	2	hSpCas9	negative selection	9024810
50564960	50564983	20	+	27260156	SU8686	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.3932477625403946	[303]	[373,376,411,427]	6	hSpCas9	negative selection	9024811
50510546	50510569	20	+	27260156	SKES1	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.14769540453319407	[638]	[862,772,626,597]	3	hSpCas9	negative selection	9081801
50564973	50564996	20	-	27260156	SKES1	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	0.13559201343688268	[361]	[451,535,283,342]	3	hSpCas9	negative selection	9081802
50510569	50510592	20	+	27260156	SKES1	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.6085173865669335	[330]	[580,579,415,457]	9	hSpCas9	negative selection	9081803
50561425	50561448	20	-	27260156	SKES1	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.00031434846041156206	[1691]	[1929,1855,1719,1325]	0	hSpCas9	negative selection	9146060
50568389	50568412	20	-	27260156	SKES1	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.10020464768164372	[924]	[892,1205,797,1055]	2	hSpCas9	negative selection	9146061
50564960	50564983	20	+	27260156	SKES1	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	-0.006475597550170575	[303]	[345,307,340,224]	0	hSpCas9	negative selection	9146062
50510546	50510569	20	+	27260156	TOV112D	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.26434900326226374	[638]	[1018,692,633,730]	5	hSpCas9	negative selection	9203052
50564973	50564996	20	-	27260156	TOV112D	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.16573354072462065	[361]	[242,506,409,174]	-3	hSpCas9	negative selection	9203053
50510569	50510592	20	+	27260156	TOV112D	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.36827707368885537	[330]	[568,439,258,456]	7	hSpCas9	negative selection	9203054
50561425	50561448	20	-	27260156	TOV112D	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.18266492287727498	[1691]	[1957,2350,1804,1690]	3	hSpCas9	negative selection	9267311
50568389	50568412	20	-	27260156	TOV112D	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	-0.3477590353167699	[924]	[529,1181,716,580]	-6	hSpCas9	negative selection	9267312
50564960	50564983	20	+	27260156	TOV112D	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.16124422021153811	[303]	[451,339,360,220]	3	hSpCas9	negative selection	9267313
50510546	50510569	20	+	27260156	TC71	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.28118338663447306	[638]	[773,706,959,888]	6	hSpCas9	negative selection	9324303
50564973	50564996	20	-	27260156	TC71	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	0.1256488250818903	[361]	[448,394,382,469]	3	hSpCas9	negative selection	9324304
50510569	50510592	20	+	27260156	TC71	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.48771693867562105	[330]	[540,479,450,519]	9	hSpCas9	negative selection	9324305
50561425	50561448	20	-	27260156	TC71	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.052430875624021045	[1691]	[1796,2058,1741,1934]	1	hSpCas9	negative selection	9388562
50568389	50568412	20	-	27260156	TC71	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.05494185433175913	[924]	[1047,1142,900,1031]	1	hSpCas9	negative selection	9388563
50564960	50564983	20	+	27260156	TC71	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.29663043438407805	[303]	[444,366,391,395]	7	hSpCas9	negative selection	9388564
50510546	50510569	20	+	27260156	TC32	viability	TTCGAGCAGATCGACAAGTCCGG	PTPN1	ENSG00000196396	0.2641534286110814	[638]	[589,691,825,779]	5	hSpCas9	negative selection	9445554
50564973	50564996	20	-	27260156	TC32	viability	GATGTAGTTTAATCCGACTATGG	PTPN1	ENSG00000196396	-0.09701067359766108	[361]	[212,215,434,471]	-2	hSpCas9	negative selection	9445555
50510569	50510592	20	+	27260156	TC32	viability	GAGCTGGGCGGCCATTTACCAGG	PTPN1	ENSG00000196396	0.5933913039522166	[330]	[563,343,459,515]	8	hSpCas9	negative selection	9445556
50561425	50561448	20	-	27260156	TC32	viability	TGACGTCTCTGTACCTATTTCGG	PTPN1	ENSG00000196396	0.09960461272430265	[1691]	[1510,1256,2441,1833]	1	hSpCas9	negative selection	9509813
50568389	50568412	20	-	27260156	TC32	viability	CAAAAGTGACCGCATGTGTTAGG	PTPN1	ENSG00000196396	0.25040215342477923	[924]	[879,876,1303,1143]	4	hSpCas9	negative selection	9509814
50564960	50564983	20	+	27260156	TC32	viability	GTCTTTCAGTTGACCATAGTCGG	PTPN1	ENSG00000196396	0.45079405878671697	[303]	[300,217,590,551]	7	hSpCas9	negative selection	9509815
50510521	50510544	20	+	27869803	HPAFII	viability after 27 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.700525345647476	[323]	[338,224,NaN]	5	hSpCas9	negative selection	9578139
50561380	50561403	20	+	27869803	HPAFII	viability after 27 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.34121465805263773	[583]	[345,155,NaN]	-3	hSpCas9	negative selection	9578141
50568383	50568406	20	-	27869803	HPAFII	viability after 27 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	-0.10382164476343048	[455]	[257,193,NaN]	-1	hSpCas9	negative selection	9578142
50579278	50579301	20	-	27869803	HPAFII	viability after 27 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	-0.7651382267013354	[431]	[125,139,NaN]	-5	hSpCas9	negative selection	9578143
50579766	50579789	20	-	27869803	HPAFII	viability after 27 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	1.0675384070948424	[198]	[323,131,NaN]	8	hSpCas9	negative selection	9578144
50581304	50581327	20	+	27869803	HPAFII	viability after 27 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	0.3379262583298255	[41]	[58,1,NaN]	2	hSpCas9	negative selection	9578145
50510521	50510544	20	+	27869803	HPAFII	viability after 15 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.5481682086504689	[323]	[502,512,NaN]	6	hSpCas9	negative selection	9660588
50561380	50561403	20	+	27869803	HPAFII	viability after 15 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.011103315785924384	[583]	[940,424,NaN]	0	hSpCas9	negative selection	9660590
50568383	50568406	20	-	27869803	HPAFII	viability after 15 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.4573749218225607	[455]	[802,591,NaN]	5	hSpCas9	negative selection	9660591
50579278	50579301	20	-	27869803	HPAFII	viability after 15 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	-0.37427014609372733	[431]	[454,297,NaN]	-4	hSpCas9	negative selection	9660592
50579766	50579789	20	-	27869803	HPAFII	viability after 15 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	1.2978354159175813	[198]	[769,373,NaN]	9	hSpCas9	negative selection	9660593
50581304	50581327	20	+	27869803	HPAFII	viability after 15 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	0.3914402195017126	[41]	[147,3,NaN]	4	hSpCas9	negative selection	9660594
50510521	50510544	20	+	27869803	ASPC1	viability after 36 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.6564365411322546	[771]	[464,250,529]	6	hSpCas9	negative selection	9743037
50561380	50561403	20	+	27869803	ASPC1	viability after 36 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.05527358961000117	[1560]	[520,418,604]	0	hSpCas9	negative selection	9743039
50568383	50568406	20	-	27869803	ASPC1	viability after 36 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.44963318429273547	[1416]	[819,531,680]	4	hSpCas9	negative selection	9743040
50579278	50579301	20	-	27869803	ASPC1	viability after 36 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.060029427793550805	[881]	[574,362,105]	0	hSpCas9	negative selection	9743041
50579766	50579789	20	-	27869803	ASPC1	viability after 36 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.7137769533410196	[753]	[726,253,360]	7	hSpCas9	negative selection	9743042
50581304	50581327	20	+	27869803	ASPC1	viability after 36 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-4.833064652036264	[81]	[0,0,0]	-9	hSpCas9	negative selection	9743043
50510521	50510544	20	+	27869803	PATU8988S	viability after 35 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.15007892028790326	[843]	[458,294,NaN]	1	hSpCas9	negative selection	9825486
50561380	50561403	20	+	27869803	PATU8988S	viability after 35 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	0.8934047407541557	[1152]	[903,820,NaN]	8	hSpCas9	negative selection	9825488
50568383	50568406	20	-	27869803	PATU8988S	viability after 35 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.8573223266559902	[1062]	[827,722,NaN]	8	hSpCas9	negative selection	9825489
50579278	50579301	20	-	27869803	PATU8988S	viability after 35 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.2879474871065275	[840]	[428,397,NaN]	3	hSpCas9	negative selection	9825490
50579766	50579789	20	-	27869803	PATU8988S	viability after 35 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.9037929830870788	[658]	[531,460,NaN]	8	hSpCas9	negative selection	9825491
50581304	50581327	20	+	27869803	PATU8988S	viability after 35 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-3.44366654043309	[107]	[2,4,NaN]	-9	hSpCas9	negative selection	9825492
50510521	50510544	20	+	27869803	PATU8988S	viability after 31 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.24365203616542197	[843]	[485,286,NaN]	3	hSpCas9	negative selection	9907935
50561380	50561403	20	+	27869803	PATU8988S	viability after 31 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	0.8043102603005092	[1152]	[746,873,NaN]	8	hSpCas9	negative selection	9907937
50568383	50568406	20	-	27869803	PATU8988S	viability after 31 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	0.8991898617262049	[1062]	[764,822,NaN]	8	hSpCas9	negative selection	9907938
50579278	50579301	20	-	27869803	PATU8988S	viability after 31 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	0.3299367090387395	[840]	[384,467,NaN]	4	hSpCas9	negative selection	9907939
50579766	50579789	20	-	27869803	PATU8988S	viability after 31 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	0.5631051341694007	[658]	[345,441,NaN]	6	hSpCas9	negative selection	9907940
50581304	50581327	20	+	27869803	PATU8988S	viability after 31 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	-3.1295758289391435	[107]	[7,0,NaN]	-9	hSpCas9	negative selection	9907941
50510521	50510544	20	+	27869803	HPAFII	viability after 35 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.5813415220224956	[323]	[259,228,NaN]	4	hSpCas9	negative selection	9990384
50561380	50561403	20	+	27869803	HPAFII	viability after 35 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.919412463676273	[583]	[200,105,NaN]	-5	hSpCas9	negative selection	9990386
50568383	50568406	20	-	27869803	HPAFII	viability after 35 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	-0.4569574306765211	[455]	[170,164,NaN]	-3	hSpCas9	negative selection	9990387
50579278	50579301	20	-	27869803	HPAFII	viability after 35 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	-0.34500995233570586	[431]	[63,293,NaN]	-2	hSpCas9	negative selection	9990388
50579766	50579789	20	-	27869803	HPAFII	viability after 35 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	1.0847442491807733	[198]	[271,147,NaN]	7	hSpCas9	negative selection	9990389
50581304	50581327	20	+	27869803	HPAFII	viability after 35 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	1.8214761232219288	[41]	[140,0,NaN]	9	hSpCas9	negative selection	9990390
50510521	50510544	20	+	27869803	HPAFII	viability after 31 days	GCCCGTCATGGAGATGGAAAAGG	PTPN1	ENSG00000196396	0.7517170456880458	[323]	[309,301,NaN]	5	hSpCas9	negative selection	10072833
50561380	50561403	20	+	27869803	HPAFII	viability after 31 days	CAGTGACTTCCCATGTAGAGTGG	PTPN1	ENSG00000196396	-0.6116195217052137	[583]	[247,177,NaN]	-4	hSpCas9	negative selection	10072835
50568383	50568406	20	-	27869803	HPAFII	viability after 31 days	TGACCGCATGTGTTAGGCAAAGG	PTPN1	ENSG00000196396	-0.8106121128617324	[455]	[154,135,NaN]	-5	hSpCas9	negative selection	10072836
50579278	50579301	20	-	27869803	HPAFII	viability after 31 days	TGGCACCTTCGATCACAGCCAGG	PTPN1	ENSG00000196396	-0.6055257637925396	[431]	[99,223,NaN]	-4	hSpCas9	negative selection	10072837
50579766	50579789	20	-	27869803	HPAFII	viability after 31 days	AGGATTCGTTTGGGTGGCCGGGG	PTPN1	ENSG00000196396	1.2237046814223944	[198]	[323,191,NaN]	8	hSpCas9	negative selection	10072838
50581304	50581327	20	+	27869803	HPAFII	viability after 31 days	GGGAAGTCTTCGAGGTGCCCAGG	PTPN1	ENSG00000196396	0.33240352160923825	[41]	[55,0,NaN]	2	hSpCas9	negative selection	10072839
50568418	50568441	20	+	28162770	P31FUJ	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	0.17055348981683016	[30]	[40]	1	hSpCas9	negative selection	10219745
50561389	50561412	20	-	28162770	P31FUJ	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	0.43727690994472845	[542]	[863]	5	hSpCas9	negative selection	10219746
50579837	50579860	20	+	28162770	P31FUJ	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-3.51659517041497	[223]	[22]	-9	hSpCas9	negative selection	10219747
50581346	50581369	20	+	28162770	P31FUJ	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	0.2089032453265453	[133]	[181]	2	hSpCas9	negative selection	10219748
50581438	50581461	20	-	28162770	P31FUJ	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	-0.026351326946952303	[246]	[284]	0	hSpCas9	negative selection	10219749
50581448	50581471	20	-	28162770	P31FUJ	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	0.5556936903919094	[43]	[75]	6	hSpCas9	negative selection	10219750
50568402	50568425	20	+	28162770	P31FUJ	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	0.7323273357385691	[334]	[653]	8	hSpCas9	negative selection	10219751
50578598	50578621	20	-	28162770	P31FUJ	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	0.9969321922632375	[83]	[196]	9	hSpCas9	negative selection	10219752
50579689	50579712	20	+	28162770	P31FUJ	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	0.2614619860150402	[185]	[261]	3	hSpCas9	negative selection	10219753
50579815	50579838	20	+	28162770	P31FUJ	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	0.08821538552582375	[316]	[395]	0	hSpCas9	negative selection	10219754
50568418	50568441	20	+	28162770	TF1	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10389111
50561389	50561412	20	-	28162770	TF1	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	NaN	[NaN]	[402]	1	hSpCas9	negative selection	10389112
50579837	50579860	20	+	28162770	TF1	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10389113
50581346	50581369	20	+	28162770	TF1	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	NaN	[NaN]	[16]	1	hSpCas9	negative selection	10389114
50581438	50581461	20	-	28162770	TF1	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	NaN	[NaN]	[182]	1	hSpCas9	negative selection	10389115
50581448	50581471	20	-	28162770	TF1	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10389116
50568402	50568425	20	+	28162770	TF1	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	NaN	[NaN]	[237]	1	hSpCas9	negative selection	10389117
50578598	50578621	20	-	28162770	TF1	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10389118
50579689	50579712	20	+	28162770	TF1	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10389119
50579815	50579838	20	+	28162770	TF1	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	NaN	[NaN]	[271]	1	hSpCas9	negative selection	10389120
50568418	50568441	20	+	28162770	SKM1	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	-1.3694894933244988	[18]	[12]	-7	hSpCas9	negative selection	10558477
50561389	50561412	20	-	28162770	SKM1	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	0.5800967455493398	[153]	[406]	5	hSpCas9	negative selection	10558478
50579837	50579860	20	+	28162770	SKM1	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-2.7118187802715825	[62]	[16]	-9	hSpCas9	negative selection	10558479
50581346	50581369	20	+	28162770	SKM1	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	-0.05466245481228055	[46]	[79]	0	hSpCas9	negative selection	10558480
50581438	50581461	20	-	28162770	SKM1	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	-0.495500873344819	[62]	[78]	-4	hSpCas9	negative selection	10558481
50581448	50581471	20	-	28162770	SKM1	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	0.8174085867215272	[25]	[80]	7	hSpCas9	negative selection	10558482
50568402	50568425	20	+	28162770	SKM1	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	0.9651045401917931	[81]	[282]	8	hSpCas9	negative selection	10558483
50578598	50578621	20	-	28162770	SKM1	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	0.1779983019779945	[38]	[77]	1	hSpCas9	negative selection	10558484
50579689	50579712	20	+	28162770	SKM1	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	-0.2436419321250964	[72]	[108]	-2	hSpCas9	negative selection	10558485
50579815	50579838	20	+	28162770	SKM1	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	0.19685732922931037	[75]	[153]	2	hSpCas9	negative selection	10558486
50568418	50568441	20	+	28162770	SKM1	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	-1.3694894933244988	[18]	[12]	-7	hSpCas9	negative selection	10727843
50561389	50561412	20	-	28162770	SKM1	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	0.5800967455493398	[153]	[406]	5	hSpCas9	negative selection	10727844
50579837	50579860	20	+	28162770	SKM1	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-2.7118187802715825	[62]	[16]	-9	hSpCas9	negative selection	10727845
50581346	50581369	20	+	28162770	SKM1	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	-0.05466245481228055	[46]	[79]	0	hSpCas9	negative selection	10727846
50581438	50581461	20	-	28162770	SKM1	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	-0.495500873344819	[62]	[78]	-4	hSpCas9	negative selection	10727847
50581448	50581471	20	-	28162770	SKM1	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	0.8174085867215272	[25]	[80]	7	hSpCas9	negative selection	10727848
50568402	50568425	20	+	28162770	SKM1	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	0.9651045401917931	[81]	[282]	8	hSpCas9	negative selection	10727849
50578598	50578621	20	-	28162770	SKM1	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	0.1779983019779945	[38]	[77]	1	hSpCas9	negative selection	10727850
50579689	50579712	20	+	28162770	SKM1	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	-0.2436419321250964	[72]	[108]	-2	hSpCas9	negative selection	10727851
50579815	50579838	20	+	28162770	SKM1	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	0.19685732922931037	[75]	[153]	2	hSpCas9	negative selection	10727852
50568418	50568441	20	+	28162770	PL21	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	-0.22870368431455423	[34]	[12]	-2	hSpCas9	negative selection	10897209
50561389	50561412	20	-	28162770	PL21	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	0.2428440654435584	[465]	[239]	2	hSpCas9	negative selection	10897210
50579837	50579860	20	+	28162770	PL21	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-2.1097156480974673	[237]	[23]	-8	hSpCas9	negative selection	10897211
50581346	50581369	20	+	28162770	PL21	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	-2.098827331954731	[186]	[18]	-8	hSpCas9	negative selection	10897212
50581438	50581461	20	-	28162770	PL21	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	-0.027888341516560528	[170]	[72]	0	hSpCas9	negative selection	10897213
50581448	50581471	20	-	28162770	PL21	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	-0.014873276481530251	[64]	[27]	0	hSpCas9	negative selection	10897214
50568402	50568425	20	+	28162770	PL21	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	0.20606444844642546	[242]	[121]	1	hSpCas9	negative selection	10897215
50578598	50578621	20	-	28162770	PL21	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	0.9005793326304126	[79]	[64]	7	hSpCas9	negative selection	10897216
50579689	50579712	20	+	28162770	PL21	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	0.395864085363688	[116]	[66]	3	hSpCas9	negative selection	10897217
50579815	50579838	20	+	28162770	PL21	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	0.6283766115230232	[271]	[182]	5	hSpCas9	negative selection	10897218
50568418	50568441	20	+	28162770	P31FUJ	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	0.17055348981683016	[30]	[40]	1	hSpCas9	negative selection	11066575
50561389	50561412	20	-	28162770	P31FUJ	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	0.43727690994472845	[542]	[863]	5	hSpCas9	negative selection	11066576
50579837	50579860	20	+	28162770	P31FUJ	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-3.51659517041497	[223]	[22]	-9	hSpCas9	negative selection	11066577
50581346	50581369	20	+	28162770	P31FUJ	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	0.2089032453265453	[133]	[181]	2	hSpCas9	negative selection	11066578
50581438	50581461	20	-	28162770	P31FUJ	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	-0.026351326946952303	[246]	[284]	0	hSpCas9	negative selection	11066579
50581448	50581471	20	-	28162770	P31FUJ	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	0.5556936903919094	[43]	[75]	6	hSpCas9	negative selection	11066580
50568402	50568425	20	+	28162770	P31FUJ	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	0.7323273357385691	[334]	[653]	8	hSpCas9	negative selection	11066581
50578598	50578621	20	-	28162770	P31FUJ	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	0.9969321922632375	[83]	[196]	9	hSpCas9	negative selection	11066582
50579689	50579712	20	+	28162770	P31FUJ	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	0.2614619860150402	[185]	[261]	3	hSpCas9	negative selection	11066583
50579815	50579838	20	+	28162770	P31FUJ	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	0.08821538552582375	[316]	[395]	0	hSpCas9	negative selection	11066584
50568418	50568441	20	+	28162770	OCIAML5	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	0.3958609425795885	[7]	[18]	3	hSpCas9	negative selection	11235941
50561389	50561412	20	-	28162770	OCIAML5	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	1.0328569046893108	[374]	[1384]	8	hSpCas9	negative selection	11235942
50579837	50579860	20	+	28162770	OCIAML5	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-3.0891057681648464	[131]	[27]	-9	hSpCas9	negative selection	11235943
50581346	50581369	20	+	28162770	OCIAML5	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	0.9238931549180729	[72]	[249]	7	hSpCas9	negative selection	11235944
50581438	50581461	20	-	28162770	OCIAML5	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	0.9249944288800078	[109]	[376]	7	hSpCas9	negative selection	11235945
50581448	50581471	20	-	28162770	OCIAML5	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	0.6649918653553556	[57]	[165]	6	hSpCas9	negative selection	11235946
50568402	50568425	20	+	28162770	OCIAML5	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	1.447601563949089	[208]	[1028]	9	hSpCas9	negative selection	11235947
50578598	50578621	20	-	28162770	OCIAML5	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	1.794823679000361	[56]	[356]	9	hSpCas9	negative selection	11235948
50579689	50579712	20	+	28162770	OCIAML5	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	1.3726397163106974	[88]	[415]	9	hSpCas9	negative selection	11235949
50579815	50579838	20	+	28162770	OCIAML5	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	1.106685142868486	[203]	[792]	8	hSpCas9	negative selection	11235950
50568418	50568441	20	+	28162770	EOL1	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	3.519291293084276	[48]	[295]	9	hSpCas9	negative selection	11405307
50561389	50561412	20	-	28162770	EOL1	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	0.27419328486575156	[597]	[380]	2	hSpCas9	negative selection	11405308
50579837	50579860	20	+	28162770	EOL1	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-3.06337939612889	[475]	[29]	-9	hSpCas9	negative selection	11405309
50581346	50581369	20	+	28162770	EOL1	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	0.1274320340177685	[350]	[201]	1	hSpCas9	negative selection	11405310
50581438	50581461	20	-	28162770	EOL1	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	0.13894740215345186	[361]	[209]	1	hSpCas9	negative selection	11405311
50581448	50581471	20	-	28162770	EOL1	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	-1.763508222114725	[115]	[17]	-8	hSpCas9	negative selection	11405312
50568402	50568425	20	+	28162770	EOL1	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	0.881711573660277	[375]	[364]	7	hSpCas9	negative selection	11405313
50578598	50578621	20	-	28162770	EOL1	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	-0.5869525672096005	[133]	[46]	-4	hSpCas9	negative selection	11405314
50579689	50579712	20	+	28162770	EOL1	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	-0.3940599650252165	[216]	[86]	-3	hSpCas9	negative selection	11405315
50579815	50579838	20	+	28162770	EOL1	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	0.8852586404564773	[334]	[325]	7	hSpCas9	negative selection	11405316
50568418	50568441	20	+	28162770	MOLM13	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	1.3747799771530973	[23]	[44]	9	hSpCas9	negative selection	11574673
50561389	50561412	20	-	28162770	MOLM13	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	1.1441246281775994	[785]	[1255]	8	hSpCas9	negative selection	11574674
50579837	50579860	20	+	28162770	MOLM13	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-1.505735203031124	[270]	[68]	-6	hSpCas9	negative selection	11574675
50581346	50581369	20	+	28162770	MOLM13	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	0.8724345070057802	[206]	[273]	6	hSpCas9	negative selection	11574676
50581438	50581461	20	-	28162770	MOLM13	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	1.9868988092392015	[275]	[790]	9	hSpCas9	negative selection	11574677
50581448	50581471	20	-	28162770	MOLM13	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	2.4215506668777094	[86]	[336]	9	hSpCas9	negative selection	11574678
50568402	50568425	20	+	28162770	MOLM13	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	-0.18100044596612785	[322]	[205]	-1	hSpCas9	negative selection	11574679
50578598	50578621	20	-	28162770	MOLM13	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	0.5413515434855999	[133]	[140]	4	hSpCas9	negative selection	11574680
50579689	50579712	20	+	28162770	MOLM13	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	0.683797769310828	[222]	[258]	5	hSpCas9	negative selection	11574681
50579815	50579838	20	+	28162770	MOLM13	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	-0.22398832309308947	[608]	[376]	-1	hSpCas9	negative selection	11574682
50568418	50568441	20	+	28162770	HEL	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	1.4571831788442804	[28]	[50]	9	hSpCas9	negative selection	11744039
50561389	50561412	20	-	28162770	HEL	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	0.7074222016041318	[566]	[592]	6	hSpCas9	negative selection	11744040
50579837	50579860	20	+	28162770	HEL	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-1.4650644575341578	[249]	[57]	-7	hSpCas9	negative selection	11744041
50581346	50581369	20	+	28162770	HEL	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	0.19407055484023306	[216]	[158]	1	hSpCas9	negative selection	11744042
50581438	50581461	20	-	28162770	HEL	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	0.6566110065819144	[206]	[208]	5	hSpCas9	negative selection	11744043
50581448	50581471	20	-	28162770	HEL	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	0.22770133272151316	[75]	[56]	1	hSpCas9	negative selection	11744044
50568402	50568425	20	+	28162770	HEL	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	0.24239784392821512	[292]	[221]	2	hSpCas9	negative selection	11744045
50578598	50578621	20	-	28162770	HEL	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	0.5882910479779807	[107]	[103]	5	hSpCas9	negative selection	11744046
50579689	50579712	20	+	28162770	HEL	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	-0.4316860091261978	[178]	[84]	-3	hSpCas9	negative selection	11744047
50579815	50579838	20	+	28162770	HEL	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	0.07965944917765067	[457]	[309]	0	hSpCas9	negative selection	11744048
50568418	50568441	20	+	28162770	MV411	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	2.2309494279942066	[21]	[86]	9	hSpCas9	negative selection	11913405
50561389	50561412	20	-	28162770	MV411	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	2.2723317299336196	[473]	[1928]	9	hSpCas9	negative selection	11913406
50579837	50579860	20	+	28162770	MV411	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-2.916061181500104	[223]	[24]	-9	hSpCas9	negative selection	11913407
50581346	50581369	20	+	28162770	MV411	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	1.759048309756672	[194]	[555]	9	hSpCas9	negative selection	11913408
50581438	50581461	20	-	28162770	MV411	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	2.050823570637434	[207]	[725]	9	hSpCas9	negative selection	11913409
50581448	50581471	20	-	28162770	MV411	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	0.7169228340839955	[64]	[89]	6	hSpCas9	negative selection	11913410
50568402	50568425	20	+	28162770	MV411	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	3.0479744306569803	[302]	[2110]	9	hSpCas9	negative selection	11913411
50578598	50578621	20	-	28162770	MV411	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	1.255519897080634	[88]	[178]	9	hSpCas9	negative selection	11913412
50579689	50579712	20	+	28162770	MV411	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	1.5596504908369258	[148]	[369]	9	hSpCas9	negative selection	11913413
50579815	50579838	20	+	28162770	MV411	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	1.1083157486344577	[222]	[404]	8	hSpCas9	negative selection	11913414
50568418	50568441	20	+	28162770	MONOMAC1	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	1.4767349206194587	[20]	[66]	9	hSpCas9	negative selection	12082771
50561389	50561412	20	-	28162770	MONOMAC1	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	1.061239204712691	[328]	[786]	8	hSpCas9	negative selection	12082772
50579837	50579860	20	+	28162770	MONOMAC1	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-1.4757528751256173	[147]	[60]	-8	hSpCas9	negative selection	12082773
50581346	50581369	20	+	28162770	MONOMAC1	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	1.3494515058469667	[75]	[221]	9	hSpCas9	negative selection	12082774
50581438	50581461	20	-	28162770	MONOMAC1	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	0.7928389356667388	[142]	[283]	7	hSpCas9	negative selection	12082775
50581448	50581471	20	-	28162770	MONOMAC1	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	-0.4100305703937521	[50]	[43]	-4	hSpCas9	negative selection	12082776
50568402	50568425	20	+	28162770	MONOMAC1	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	1.6024702131753652	[157]	[549]	9	hSpCas9	negative selection	12082777
50578598	50578621	20	-	28162770	MONOMAC1	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	1.0473818806068933	[64]	[153]	8	hSpCas9	negative selection	12082778
50579689	50579712	20	+	28162770	MONOMAC1	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	0.8844930384370446	[85]	[181]	7	hSpCas9	negative selection	12082779
50579815	50579838	20	+	28162770	MONOMAC1	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	-0.2826125787656275	[190]	[179]	-3	hSpCas9	negative selection	12082780
50568418	50568441	20	+	28162770	OCIAML2	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	1.2298098928989307	[1]	[25]	9	hSpCas9	negative selection	12252137
50561389	50561412	20	-	28162770	OCIAML2	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	0.06674321696073471	[112]	[655]	0	hSpCas9	negative selection	12252138
50579837	50579860	20	+	28162770	OCIAML2	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	-3.0555923259633175	[38]	[25]	-9	hSpCas9	negative selection	12252139
50581346	50581369	20	+	28162770	OCIAML2	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	0.3273263988131933	[21]	[152]	3	hSpCas9	negative selection	12252140
50581438	50581461	20	-	28162770	OCIAML2	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	0.5849625007211562	[34]	[290]	5	hSpCas9	negative selection	12252141
50581448	50581471	20	-	28162770	OCIAML2	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	0.06993855612054145	[10]	[63]	0	hSpCas9	negative selection	12252142
50568402	50568425	20	+	28162770	OCIAML2	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	0.7937107780922574	[45]	[441]	7	hSpCas9	negative selection	12252143
50578598	50578621	20	-	28162770	OCIAML2	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	0.22124787939550689	[25]	[167]	2	hSpCas9	negative selection	12252144
50579689	50579712	20	+	28162770	OCIAML2	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	0.6791172942625208	[31]	[283]	6	hSpCas9	negative selection	12252145
50579815	50579838	20	+	28162770	OCIAML2	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	0.12928301694496647	[47]	[290]	1	hSpCas9	negative selection	12252146
50568418	50568441	20	+	28162770	OCIAML3	viability	GGTGTGGGAGCAGAAAAGCAGGG	PTPN1	ENSG00000196396	1.7279204545631988	[2]	[29]	9	hSpCas9	negative selection	12421503
50561389	50561412	20	-	28162770	OCIAML3	viability	GAAGCTTGGCCACTCTACATGGG	PTPN1	ENSG00000196396	0.281470002652894	[129]	[476]	2	hSpCas9	negative selection	12421504
50579837	50579860	20	+	28162770	OCIAML3	viability	GGTGAAGGAAGAGACCCAGGAGG	PTPN1	ENSG00000196396	0.8829349894733022	[66]	[372]	7	hSpCas9	negative selection	12421505
50581346	50581369	20	+	28162770	OCIAML3	viability	GGAGCCGTCACTGCCCGAGAAGG	PTPN1	ENSG00000196396	0.7430273469534076	[37]	[191]	6	hSpCas9	negative selection	12421506
50581438	50581461	20	-	28162770	OCIAML3	viability	CCTGTAGCAGAGGTAAGCGCCGG	PTPN1	ENSG00000196396	-0.6884723243276555	[70]	[132]	-5	hSpCas9	negative selection	12421507
50581448	50581471	20	-	28162770	OCIAML3	viability	GGAAACATACCCTGTAGCAGAGG	PTPN1	ENSG00000196396	1.371776644337924	[15]	[124]	9	hSpCas9	negative selection	12421508
50568402	50568425	20	+	28162770	OCIAML3	viability	GTCACTTTTGGGAGATGGTGTGG	PTPN1	ENSG00000196396	-0.17897014104531928	[92]	[247]	-1	hSpCas9	negative selection	12421509
50578598	50578621	20	-	28162770	OCIAML3	viability	GCAGGTATCAGCCAGACAGAAGG	PTPN1	ENSG00000196396	1.150153455246247	[19]	[133]	8	hSpCas9	negative selection	12421510
50579689	50579712	20	+	28162770	OCIAML3	viability	GCTGCTCTTTCAAGGATCAGTGG	PTPN1	ENSG00000196396	0.35049724708413316	[52]	[203]	3	hSpCas9	negative selection	12421511
50579815	50579838	20	+	28162770	OCIAML3	viability	AGTTCTTCCCAAATCACCAGTGG	PTPN1	ENSG00000196396	0.6635516354434796	[54]	[262]	6	hSpCas9	negative selection	12421512