Crispr

Gene Info

• Species: Human (Homo sapiens)
• GeneID: 5781
• Symbol: PTPN11
• Description: protein tyrosine phosphatase non-receptor type 11

DataSource: http://genomecrispr.dkfz.de/#!/results/PTPN11

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
112419104	112419127	12	+	26472758	Jiyoye	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-0.01551569031640554	[62]	[46]	0	hSpCas9	negative selection	130958
112502237	112502260	12	-	26472758	Jiyoye	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	2.9432282817460833	[9]	[57]	9	hSpCas9	negative selection	130959
112486476	112486499	12	+	26472758	Jiyoye	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	0.6107087755910052	[32]	[37]	4	hSpCas9	negative selection	130960
112453315	112453338	12	+	26472758	Jiyoye	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	-0.2513902092552807	[190]	[120]	-2	hSpCas9	negative selection	130961
112486527	112486550	12	+	26472758	Jiyoye	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.7090657231566909	[231]	[285]	5	hSpCas9	negative selection	130962
112454659	112454682	12	+	26472758	Jiyoye	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	1.2291770795278787	[55]	[98]	7	hSpCas9	negative selection	130963
112450499	112450522	12	-	26472758	Jiyoye	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.015295603214282028	[205]	[156]	0	hSpCas9	negative selection	130964
112456042	112456065	12	+	26472758	Jiyoye	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	-0.03730589566545239	[395]	[290]	0	hSpCas9	negative selection	130965
112446377	112446400	12	+	26472758	Jiyoye	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.18923065262689698	[442]	[292]	-1	hSpCas9	negative selection	130966
112453301	112453324	12	+	26472758	Jiyoye	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	-0.4341268724750684	[343]	[191]	-3	hSpCas9	negative selection	130967
112419104	112419127	12	+	26472758	KBM7	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-4.1747363315676225	[243,197]	[10,0]	-9	hSpCas9	negative selection	322076
112502237	112502260	12	-	26472758	KBM7	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	0.31715930336058085	[298,356]	[254,140]	3	hSpCas9	negative selection	322077
112486476	112486499	12	+	26472758	KBM7	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-1.9289967827494716	[294,268]	[56,14]	-8	hSpCas9	negative selection	322078
112453315	112453338	12	+	26472758	KBM7	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	-1.1339232607868615	[479,260]	[60,91]	-7	hSpCas9	negative selection	322079
112486527	112486550	12	+	26472758	KBM7	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.3989492685595897	[1462,1101]	[720,846]	4	hSpCas9	negative selection	322080
112454659	112454682	12	+	26472758	KBM7	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-1.0250875254581941	[633,599]	[192,97]	-7	hSpCas9	negative selection	322081
112450499	112450522	12	-	26472758	KBM7	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.8676178369895878	[795,950]	[138,307]	-6	hSpCas9	negative selection	322082
112456042	112456065	12	+	26472758	KBM7	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	-0.35518786845137873	[1324,1146]	[392,506]	-3	hSpCas9	negative selection	322083
112446377	112446400	12	+	26472758	KBM7	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-1.7595952183895283	[1993,1877]	[234,299]	-8	hSpCas9	negative selection	322084
112453301	112453324	12	+	26472758	KBM7	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	1.104314438417627	[1140,1127]	[1061,1231]	9	hSpCas9	negative selection	322085
112419104	112419127	12	+	26472758	Raji	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	1.4669259220607396	[52]	[33]	9	hSpCas9	negative selection	513194
112502237	112502260	12	-	26472758	Raji	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	-0.008093682046336481	[194]	[44]	0	hSpCas9	negative selection	513195
112486476	112486499	12	+	26472758	Raji	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-0.7930807910754862	[111]	[14]	-6	hSpCas9	negative selection	513196
112453315	112453338	12	+	26472758	Raji	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	0.8156174109964894	[141]	[57]	7	hSpCas9	negative selection	513197
112486527	112486550	12	+	26472758	Raji	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.5730471077224115	[503]	[173]	5	hSpCas9	negative selection	513198
112454659	112454682	12	+	26472758	Raji	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.1166181388245055	[298]	[63]	-1	hSpCas9	negative selection	513199
112450499	112450522	12	-	26472758	Raji	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.0762348368029353	[514]	[125]	0	hSpCas9	negative selection	513200
112456042	112456065	12	+	26472758	Raji	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	-0.23500866207347837	[851]	[167]	-2	hSpCas9	negative selection	513201
112446377	112446400	12	+	26472758	Raji	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.10206973547713183	[1087]	[270]	0	hSpCas9	negative selection	513202
112453301	112453324	12	+	26472758	Raji	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.6678192340980058	[612]	[225]	6	hSpCas9	negative selection	513203
112419104	112419127	12	+	26472758	K562	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-2.7951096365201913	[147]	[17]	-8	hSpCas9	negative selection	704312
112502237	112502260	12	-	26472758	K562	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	0.18716141005724635	[256]	[246]	1	hSpCas9	negative selection	704313
112486476	112486499	12	+	26472758	K562	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-7.263375912532249	[181]	[0]	-9	hSpCas9	negative selection	704314
112453315	112453338	12	+	26472758	K562	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	-1.7042624950485732	[358]	[92]	-7	hSpCas9	negative selection	704315
112486527	112486550	12	+	26472758	K562	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	-2.199187923809168	[951]	[174]	-7	hSpCas9	negative selection	704316
112454659	112454682	12	+	26472758	K562	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-4.524647709666784	[408]	[14]	-9	hSpCas9	negative selection	704317
112450499	112450522	12	-	26472758	K562	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-1.7244361698515736	[778]	[198]	-7	hSpCas9	negative selection	704318
112456042	112456065	12	+	26472758	K562	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	-0.28520073921093436	[1073]	[743]	-2	hSpCas9	negative selection	704319
112446377	112446400	12	+	26472758	K562	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-2.9000583614760416	[1741]	[196]	-8	hSpCas9	negative selection	704320
112453301	112453324	12	+	26472758	K562	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.70428600840607	[902]	[1241]	6	hSpCas9	negative selection	704321
112502243	112502266	12	-	26627737	DLD1	viability	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-0.46272334972050644	[416]	[63,142,80]	-5	hSpCas9	negative selection	782261
112502246	112502269	12	-	26627737	DLD1	viability	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-0.6038020805224323	[704]	[274,107,62]	-5	hSpCas9	negative selection	782262
112502243	112502266	12	-	26627737	GBM cells	viability after 5 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-1.155533909136691	[188]	[32,57]	-9	hSpCas9	negative selection	864576
112502246	112502269	12	-	26627737	GBM cells	viability after 5 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-0.9932828355797995	[231]	[50,73]	-9	hSpCas9	negative selection	864577
112502243	112502266	12	-	26627737	GBM cells	viability after 13 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-1.3584764314276505	[188]	[23,52]	-8	hSpCas9	negative selection	946891
112502246	112502269	12	-	26627737	GBM cells	viability after 13 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-0.7677152516067498	[231]	[79,68]	-7	hSpCas9	negative selection	946892
112502243	112502266	12	-	26627737	GBM cells	viability after 21 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-0.9540886700422151	[188]	[52,52]	-7	hSpCas9	negative selection	1029206
112502246	112502269	12	-	26627737	GBM cells	viability after 21 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-1.007354157597237	[231]	[57,66]	-7	hSpCas9	negative selection	1029207
112502243	112502266	12	-	26627737	RPE1	viability after 9 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-0.9411718023696566	[842]	[143,128]	-6	hSpCas9	negative selection	1111521
112502246	112502269	12	-	26627737	RPE1	viability after 9 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-0.35237057053187465	[724]	[134,232]	-2	hSpCas9	negative selection	1111522
112502243	112502266	12	-	26627737	RPE1	viability after 12 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-1.7726513361989762	[842]	[58,73]	-8	hSpCas9	negative selection	1193836
112502246	112502269	12	-	26627737	RPE1	viability after 12 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-1.0880001517324784	[724]	[78,104]	-6	hSpCas9	negative selection	1193837
112502243	112502266	12	-	26627737	RPE1	viability after 15 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-2.1185965760943253	[842]	[87,22]	-8	hSpCas9	negative selection	1276151
112502246	112502269	12	-	26627737	RPE1	viability after 15 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-0.597409416061354	[724]	[188,83]	-4	hSpCas9	negative selection	1276152
112502243	112502266	12	-	26627737	RPE1	viability after 18 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-2.026155611410995	[842]	[36,75]	-8	hSpCas9	negative selection	1358466
112502246	112502269	12	-	26627737	RPE1	viability after 18 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-1.5717168810642599	[724]	[45,86]	-7	hSpCas9	negative selection	1358467
112502243	112502266	12	-	26627737	HeLa	viability after 8 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-1.0064908294398804	[344]	[98,62,67]	-8	hSpCas9	negative selection	1440781
112502246	112502269	12	-	26627737	HeLa	viability after 8 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-1.103264810303033	[428]	[91,85,83]	-8	hSpCas9	negative selection	1440782
112502243	112502266	12	-	26627737	HeLa	viability after 12 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-0.6663837438669193	[344]	[116,35,122]	-5	hSpCas9	negative selection	1523096
112502246	112502269	12	-	26627737	HeLa	viability after 12 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-1.0076175004152357	[428]	[51,54,159]	-7	hSpCas9	negative selection	1523097
112502243	112502266	12	-	26627737	HeLa	viability after 15 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-1.4907943381275321	[344]	[25,64,59]	-8	hSpCas9	negative selection	1605411
112502246	112502269	12	-	26627737	HeLa	viability after 15 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-1.9547374010116083	[428]	[6,18,114]	-9	hSpCas9	negative selection	1605412
112502243	112502266	12	-	26627737	HeLa	viability after 18 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-1.4570930421803037	[344]	[13,60,59]	-8	hSpCas9	negative selection	1687726
112502246	112502269	12	-	26627737	HeLa	viability after 18 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-1.9961997806705805	[428]	[1,15,114]	-9	hSpCas9	negative selection	1687727
112502243	112502266	12	-	26627737	HCT116	viability after 6 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-1.2345553001766048	[692]	[122,3]	-6	hSpCas9	negative selection	1770041
112502246	112502269	12	-	26627737	HCT116	viability after 6 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-0.6553494553970161	[1150]	[130,105]	-4	hSpCas9	negative selection	1770042
112502243	112502266	12	-	26627737	HCT116	viability after 8 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-0.22072019948807664	[200]	[122,97,64]	-3	hSpCas9	negative selection	1852356
112502246	112502269	12	-	26627737	HCT116	viability after 8 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-0.7606674887142789	[491]	[126,237,114]	-7	hSpCas9	negative selection	1852357
112502243	112502266	12	-	26627737	HCT116	viability after 9 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-2.1468504924878475	[692]	[81,9]	-8	hSpCas9	negative selection	1934671
112502246	112502269	12	-	26627737	HCT116	viability after 9 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-2.0738577478987446	[1150]	[134,23]	-8	hSpCas9	negative selection	1934672
112502243	112502266	12	-	26627737	HCT116	viability after 12 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-0.1520011826458464	[200]	[125,74,80]	-1	hSpCas9	negative selection	2016986
112502246	112502269	12	-	26627737	HCT116	viability after 12 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-0.930860289529196	[491]	[149,68,184]	-7	hSpCas9	negative selection	2016987
112502243	112502266	12	-	26627737	HCT116	viability after 15 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-0.09981315011966196	[200]	[103,135,82]	-1	hSpCas9	negative selection	2099301
112502246	112502269	12	-	26627737	HCT116	viability after 15 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-1.2491147175541855	[491]	[100,97,154]	-8	hSpCas9	negative selection	2099302
112502243	112502266	12	-	26627737	HCT116	viability after 18 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	0.2010928291423006	[200]	[82,115,136]	1	hSpCas9	negative selection	2181616
112502246	112502269	12	-	26627737	HCT116	viability after 18 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-1.4464166918303438	[491]	[57,114,86]	-8	hSpCas9	negative selection	2181617
112419104	112419127	12	+	24336569	HL60	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-0.9882560470499928	[913]	[974]	-7	hSpCas9	negative selection	2287547
112446377	112446400	12	+	24336569	HL60	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.41654122268237337	[415]	[1174]	4	hSpCas9	negative selection	2287548
112450499	112450522	12	-	24336569	HL60	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.9758078540199875	[736]	[792]	-7	hSpCas9	negative selection	2287549
112453196	112453219	12	+	24336569	HL60	viability	TGGTTTCATGGACATCTCTCTGG	PTPN11	ENSG00000179295	0.5105704487677616	[406]	[1226]	4	hSpCas9	negative selection	2287550
112453301	112453324	12	+	24336569	HL60	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.24306110574450512	[221]	[555]	2	hSpCas9	negative selection	2287551
112453313	112453336	12	+	24336569	HL60	viability	GTGCGCACTGGTGATGACAAAGG	PTPN11	ENSG00000179295	-0.49426659552443186	[214]	[322]	-4	hSpCas9	negative selection	2287552
112454659	112454682	12	+	24336569	HL60	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	0.3952891831363633	[428]	[1193]	3	hSpCas9	negative selection	2287553
112472937	112472960	12	+	24336569	HL60	viability	TTTCCAGACACTACAACAACAGG	PTPN11	ENSG00000179295	0.6288110722322877	[550]	[1802]	5	hSpCas9	negative selection	2287554
112473033	112473056	12	-	24336569	HL60	viability	AATATTGATACTTACAGGGCAGG	PTPN11	ENSG00000179295	0.23084307624556893	[330]	[821]	2	hSpCas9	negative selection	2287555
112477642	112477665	12	+	24336569	HL60	viability	TTCTTCTAGTTGATCATACCAGG	PTPN11	ENSG00000179295	-0.43441909113688326	[234]	[367]	-4	hSpCas9	negative selection	2287556
112419104	112419127	12	+	24336569	KBM7	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-2.80680583285922	[861]	[335]	-9	hSpCas9	negative selection	2354724
112446377	112446400	12	+	24336569	KBM7	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-3.15518661111629	[453]	[138]	-9	hSpCas9	negative selection	2354725
112450499	112450522	12	-	24336569	KBM7	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-1.2659331175557438	[394]	[447]	-7	hSpCas9	negative selection	2354726
112453196	112453219	12	+	24336569	KBM7	viability	TGGTTTCATGGACATCTCTCTGG	PTPN11	ENSG00000179295	-0.5020269805712589	[431]	[831]	-4	hSpCas9	negative selection	2354727
112453301	112453324	12	+	24336569	KBM7	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.5412802458459174	[194]	[773]	5	hSpCas9	negative selection	2354728
112453313	112453336	12	+	24336569	KBM7	viability	GTGCGCACTGGTGATGACAAAGG	PTPN11	ENSG00000179295	-8.666747717011043	[148]	[0]	-9	hSpCas9	negative selection	2354729
112454659	112454682	12	+	24336569	KBM7	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-1.3468851969294093	[165]	[177]	-7	hSpCas9	negative selection	2354730
112472937	112472960	12	+	24336569	KBM7	viability	TTTCCAGACACTACAACAACAGG	PTPN11	ENSG00000179295	0.6460097474982983	[469]	[2005]	6	hSpCas9	negative selection	2354731
112473033	112473056	12	-	24336569	KBM7	viability	AATATTGATACTTACAGGGCAGG	PTPN11	ENSG00000179295	-1.5158582653337564	[648]	[618]	-7	hSpCas9	negative selection	2354732
112477642	112477665	12	+	24336569	KBM7	viability	TTCTTCTAGTTGATCATACCAGG	PTPN11	ENSG00000179295	0.5053356673813761	[326]	[1265]	4	hSpCas9	negative selection	2354733
112445665	112445688	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTTTCGCTCTTGTTGCCCAAG	PTPN11	ENSG00000179295	-0.7837275452001344	[95,22]	[7,5]	-4	dCas9-VP64	positive selection	2394500
112493099	112493122	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGGCACTGCACTCCAGCCTTAG	PTPN11	ENSG00000179295	0.14919512582895444	[137,141]	[31,35]	0	dCas9-VP64	positive selection	2409481
112497014	112497037	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATACAAAAATTAGCCAGGCGTAG	PTPN11	ENSG00000179295	0.7667043826941231	[92,346]	[53,113]	3	dCas9-VP64	positive selection	2426052
112462164	112462187	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTCTCACTATATTGCCCCGG	PTPN11	ENSG00000179295	2.346297348584061	[172,220]	[56,398]	7	dCas9-VP64	positive selection	2428388
112437249	112437272	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGCAGAATCGCTTGAACCCGG	PTPN11	ENSG00000179295	4.376878119565056	[324,400]	[1478,1870]	9	dCas9-VP64	positive selection	2470895
112445665	112445688	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTTTCGCTCTTGTTGCCCAAG	PTPN11	ENSG00000179295	-0.16320683952806103	[88,58]	[29,12]	-1	dCas9-VP64	positive selection	2489755
112493099	112493122	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGGCACTGCACTCCAGCCTTAG	PTPN11	ENSG00000179295	0.26947116138715255	[117,96]	[23,58]	2	dCas9-VP64	positive selection	2504736
112497014	112497037	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATACAAAAATTAGCCAGGCGTAG	PTPN11	ENSG00000179295	0.15255249232697954	[139,139]	[73,28]	1	dCas9-VP64	positive selection	2521307
112462164	112462187	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTCTCACTATATTGCCCCGG	PTPN11	ENSG00000179295	-0.41126224133599143	[350,385]	[99,80]	-4	dCas9-VP64	positive selection	2523643
112437249	112437272	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGCAGAATCGCTTGAACCCGG	PTPN11	ENSG00000179295	2.6681151119317885	[136,149]	[134,451]	9	dCas9-VP64	positive selection	2566150
112419105	112419128	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	0.5298117401527427	[2,2]	[2,4]	9	hSpCas9	positive selection	3014688
112450481	112450504	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGGATCTGCACAGTTCAGAGG	PTPN11	ENSG00000179295	-0.193664902466687	[2,2]	[2,1]	-3	hSpCas9	positive selection	3014689
112450492	112450515	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	0.15310999232847394	[3,3]	[4,2]	3	hSpCas9	positive selection	3014690
112446392	112446415	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTCATTCCAACTTACCTAACGG	PTPN11	ENSG00000179295	0.049457116801163714	[4,4]	[3,3]	1	hSpCas9	positive selection	3014691
112419105	112419128	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-0.7982730837747618	[2,2]	[1,0]	-9	hSpCas9	positive selection	3082546
112450481	112450504	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGGATCTGCACAGTTCAGAGG	PTPN11	ENSG00000179295	-0.7311072302074871	[2,2]	[1,0]	-8	hSpCas9	positive selection	3082547
112450492	112450515	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	0.13264869960750914	[3,3]	[3,2]	2	hSpCas9	positive selection	3082548
112446392	112446415	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTCATTCCAACTTACCTAACGG	PTPN11	ENSG00000179295	0.11800018920807584	[4,4]	[3,2]	2	hSpCas9	positive selection	3082549
112446377	112446400		+	24336571	A375	resistance to PLX after 7 days	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.7410783420132245	[14,16]	[10,7]	-9	hSpCas9	positive selection	3138773
112450499	112450522		-	24336571	A375	resistance to PLX after 7 days	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.18833408348567043	[12,12]	[11,10]	-6	hSpCas9	positive selection	3138774
112446377	112446400		+	24336571	A375	resistance to PLX after 14 days	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-1.4279757233853436	[17,15]	[2,1]	-9	hSpCas9	positive selection	3196566
112450499	112450522		-	24336571	A375	resistance to PLX after 14 days	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.5355161942635807	[9,12]	[2,3]	-6	hSpCas9	positive selection	3196567
112446377	112446400		+	24336571	A375	viability after 7 days	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.025002431783693657	[16]	[14,16]	0	hSpCas9	negative selection	3254359
112450499	112450522		-	24336571	A375	viability after 7 days	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.13102441145332394	[14]	[12,12]	-2	hSpCas9	negative selection	3254360
112446377	112446400		+	24336571	A375	viability after 14 days	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.06939619285545129	[16]	[17,15]	0	hSpCas9	negative selection	3312152
112450499	112450522		-	24336571	A375	viability after 14 days	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.2919998618043576	[14]	[9,12]	-3	hSpCas9	negative selection	3312153
112450491	112450514	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	2.3031299010589596	[30,30]	[0,0]	8	hSpCas9	positive selection	3388250
112454561	112454584	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	0.6574133692587072	[96,96]	[0,0]	3	hSpCas9	positive selection	3388251
112446373	112446396	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	0.3384629741712407	[120,120]	[0,0]	1	hSpCas9	positive selection	3388252
112419104	112419127	12	+	26780180	HT29	viability (Avana library 4 designs)	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	2.8169300941295	[]	[]	8	hSpCas9	negative selection	3452932
112450481	112450504	12	-	26780180	HT29	viability (Avana library 4 designs)	GTAGGATCTGCACAGTTCAGAGG	PTPN11	ENSG00000179295	2.43843947965137	[]	[]	8	hSpCas9	negative selection	3452933
112450491	112450514	12	+	26780180	HT29	viability (Avana library 4 designs)	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	1.14399212606788	[]	[]	4	hSpCas9	negative selection	3452934
112446392	112446415	12	-	26780180	HT29	viability (Avana library 4 designs)	TTTCATTCCAACTTACCTAACGG	PTPN11	ENSG00000179295	0.492371792441582	[]	[]	1	hSpCas9	negative selection	3452935
112419104	112419127	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-0.177365224992518	[]	[]	0	hSpCas9	negative selection	3549545
112446392	112446415	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCATTCCAACTTACCTAACGG	PTPN11	ENSG00000179295	-10.6972911586695	[]	[]	-8	hSpCas9	negative selection	3549546
112450481	112450504	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGGATCTGCACAGTTCAGAGG	PTPN11	ENSG00000179295	0.836110776204501	[]	[]	1	hSpCas9	negative selection	3549547
112450491	112450514	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	0.383776179042028	[]	[]	0	hSpCas9	negative selection	3549548
112446372	112446395	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGGAAAGTGTGAAGTCTCCAGGG	PTPN11	ENSG00000179295	1.49191757941514	[]	[]	2	hSpCas9	negative selection	3549549
112446377	112446400	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	1.74977888074239	[]	[]	2	hSpCas9	negative selection	3549550
112419104	112419127	12	+	26780180	A375	viability (Avana lentiGuide)	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-2.20404001855253	[]	[]	-4	hSpCas9	negative selection	3658204
112446392	112446415	12	-	26780180	A375	viability (Avana lentiGuide)	TTTCATTCCAACTTACCTAACGG	PTPN11	ENSG00000179295	-4.17524028634631	[]	[]	-7	hSpCas9	negative selection	3658205
112450481	112450504	12	-	26780180	A375	viability (Avana lentiGuide)	GTAGGATCTGCACAGTTCAGAGG	PTPN11	ENSG00000179295	6.44504797785546	[]	[]	5	hSpCas9	negative selection	3658206
112450491	112450514	12	+	26780180	A375	viability (Avana lentiGuide)	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-7.469161808353	[]	[]	-9	hSpCas9	negative selection	3658207
112446372	112446395	12	-	26780180	A375	viability (Avana lentiGuide)	CGGAAAGTGTGAAGTCTCCAGGG	PTPN11	ENSG00000179295	1.58317784757496	[]	[]	1	hSpCas9	negative selection	3658208
112446377	112446400	12	+	26780180	A375	viability (Avana lentiGuide)	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.348307787731934	[]	[]	0	hSpCas9	negative selection	3658209
112419104	112419127	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-0.9451557392747517	[4]	[1,1]	-8	hSpCas9	positive selection	3766811
112446392	112446415	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCATTCCAACTTACCTAACGG	PTPN11	ENSG00000179295	-0.6602845803833105	[8]	[4,4]	-7	hSpCas9	positive selection	3766812
112450481	112450504	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGGATCTGCACAGTTCAGAGG	PTPN11	ENSG00000179295	-0.2471376985058723	[4]	[3,4]	-4	hSpCas9	positive selection	3766813
112450491	112450514	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-0.09117586404935787	[5]	[5,4]	-1	hSpCas9	positive selection	3766814
112446372	112446395	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGAAAGTGTGAAGTCTCCAGGG	PTPN11	ENSG00000179295	-0.13118830739457893	[5]	[4,4]	-2	hSpCas9	positive selection	3766815
112446377	112446400	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.3924110265678016	[5]	[3,3]	-5	hSpCas9	positive selection	3766816
112419104	112419127	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-0.9653324862859387	[4]	[0,2]	-8	hSpCas9	positive selection	3875418
112446392	112446415	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCATTCCAACTTACCTAACGG	PTPN11	ENSG00000179295	0.057543359309568054	[5]	[5,4]	1	hSpCas9	positive selection	3875419
112450481	112450504	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGGATCTGCACAGTTCAGAGG	PTPN11	ENSG00000179295	-0.08973164346461528	[5]	[4,3]	-1	hSpCas9	positive selection	3875420
112450491	112450514	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-0.09034538819213982	[5]	[3,4]	-1	hSpCas9	positive selection	3875421
112446372	112446395	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGAAAGTGTGAAGTCTCCAGGG	PTPN11	ENSG00000179295	-0.834268234237239	[6]	[1,2]	-8	hSpCas9	positive selection	3875422
112446377	112446400	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.8212777732572936	[5]	[2,2]	-8	hSpCas9	positive selection	3875423
112454561	112454584	12	+	26780180	A375	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	2.20423479131684	[]	[]	9	hSpCas9	negative selection	3985837
112446373	112446396	12	-	26780180	A375	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	1.46661992226833	[]	[]	8	hSpCas9	negative selection	3985838
112446377	112446400	12	+	26780180	A375	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.743570393589147	[]	[]	2	hSpCas9	negative selection	3985839
112450491	112450514	12	+	26780180	A375	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	0.64544940476585	[]	[]	2	hSpCas9	negative selection	3985840
112450499	112450522	12	-	26780180	A375	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	1.44690004445273	[]	[]	8	hSpCas9	negative selection	3985841
112454659	112454682	12	+	26780180	A375	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	1.67007532117557	[]	[]	9	hSpCas9	negative selection	3985842
112454561	112454584	12	+	26780180	HT29	viability (GeCKOv2 library)	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	1.55683187697609	[]	[]	7	hSpCas9	negative selection	4093803
112446373	112446396	12	-	26780180	HT29	viability (GeCKOv2 library)	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	1.31481779030202	[]	[]	6	hSpCas9	negative selection	4093804
112446377	112446400	12	+	26780180	HT29	viability (GeCKOv2 library)	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.377901709889208	[]	[]	1	hSpCas9	negative selection	4093805
112450491	112450514	12	+	26780180	HT29	viability (GeCKOv2 library)	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	0.71119419710924	[]	[]	2	hSpCas9	negative selection	4093806
112450499	112450522	12	-	26780180	HT29	viability (GeCKOv2 library)	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.999129938668509	[]	[]	4	hSpCas9	negative selection	4093807
112454659	112454682	12	+	26780180	HT29	viability (GeCKOv2 library)	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	2.15574751488566	[]	[]	9	hSpCas9	negative selection	4093808
112446377	112446400	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.3714678895185683	[3]	[2,1]	-7	hSpCas9	positive selection	4164054
112450499	112450522	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.6020176225135633	[4]	[1,1]	-9	hSpCas9	positive selection	4164055
112446377	112446400	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.9268332283996259	[4]	[0,0,1,0]	-9	hSpCas9	positive selection	4228076
112450499	112450522	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.7257827734654393	[3]	[0,0,0,4]	5	hSpCas9	positive selection	4228077
112446377	112446400	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.08910868583550366	[3]	[2,2]	1	hSpCas9	positive selection	4293065
112454659	112454682	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.4218104178024341	[3]	[1,1]	-7	hSpCas9	positive selection	4293066
112450499	112450522	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.5275715226716825	[2]	[1,0]	-8	hSpCas9	positive selection	4293067
112450491	112450514	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	0.38201301907439333	[1]	[1,0]	7	hSpCas9	positive selection	4357324
112454561	112454584	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.4756189634780299	[3]	[1,0]	-8	hSpCas9	positive selection	4357325
112446373	112446396	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.12340048232309059	[2]	[2,1]	-2	hSpCas9	positive selection	4357326
112446356	112446378	12	+	27760321	OCIAML3	viability	GGCCTAGTAAAAGTAACCCTGG	PTPN11	ENSG00000179295	-0.8951607277968898	[134,108]	[37,67]	-7	hSpCas9	negative selection	4431867
112450414	112450436	12	-	27760321	OCIAML3	viability	GTGATGTTCCATGTAATACTGG	PTPN11	ENSG00000179295	-0.31653226513948995	[36,48]	[6,53]	-3	hSpCas9	negative selection	4431868
112454568	112454590	12	+	27760321	OCIAML3	viability	TGAAATACGACGTTGGTGGAGG	PTPN11	ENSG00000179295	-0.5939010822975987	[408,386]	[182,236]	-5	hSpCas9	negative selection	4431869
112454660	112454682	12	+	27760321	OCIAML3	viability	ACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.6722237135586823	[271,231]	[134,107]	-6	hSpCas9	negative selection	4431870
112477644	112477666	12	+	27760321	OCIAML3	viability	CTTCTAGTTGATCATACCAGGG	PTPN11	ENSG00000179295	-0.3081893662796158	[181,164]	[102,117]	-3	hSpCas9	negative selection	4431871
112446356	112446378	12	+	27760321	OCIAML2	viability	GGCCTAGTAAAAGTAACCCTGG	PTPN11	ENSG00000179295	-0.7910379083326122	[134,108]	[54,58]	-7	hSpCas9	negative selection	4515330
112450414	112450436	12	-	27760321	OCIAML2	viability	GTGATGTTCCATGTAATACTGG	PTPN11	ENSG00000179295	-1.98697236920462	[36,48]	[1,17]	-9	hSpCas9	negative selection	4515331
112454568	112454590	12	+	27760321	OCIAML2	viability	TGAAATACGACGTTGGTGGAGG	PTPN11	ENSG00000179295	-0.4345014809123963	[408,386]	[209,275]	-5	hSpCas9	negative selection	4515332
112454660	112454682	12	+	27760321	OCIAML2	viability	ACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	0.31628423778554565	[271,231]	[230,281]	4	hSpCas9	negative selection	4515333
112477644	112477666	12	+	27760321	OCIAML2	viability	CTTCTAGTTGATCATACCAGGG	PTPN11	ENSG00000179295	-0.09534574429366205	[181,164]	[110,157]	-1	hSpCas9	negative selection	4515334
112446356	112446378	12	+	27760321	MV411	viability	GGCCTAGTAAAAGTAACCCTGG	PTPN11	ENSG00000179295	-3.000510118740892	[134,108]	[15,0]	-9	hSpCas9	negative selection	4598793
112450414	112450436	12	-	27760321	MV411	viability	GTGATGTTCCATGTAATACTGG	PTPN11	ENSG00000179295	-1.4427849162780837	[36,48]	[0,24]	-7	hSpCas9	negative selection	4598794
112454568	112454590	12	+	27760321	MV411	viability	TGAAATACGACGTTGGTGGAGG	PTPN11	ENSG00000179295	-0.943507363300577	[408,386]	[19,311]	-6	hSpCas9	negative selection	4598795
112454660	112454682	12	+	27760321	MV411	viability	ACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-3.629879044795245	[271,231]	[0,31]	-9	hSpCas9	negative selection	4598796
112477644	112477666	12	+	27760321	MV411	viability	CTTCTAGTTGATCATACCAGGG	PTPN11	ENSG00000179295	-0.5427729765459663	[181,164]	[0,194]	-4	hSpCas9	negative selection	4598797
112446356	112446378	12	+	27760321	HL60	viability	GGCCTAGTAAAAGTAACCCTGG	PTPN11	ENSG00000179295	-1.2985726809113796	[134,108]	[49,29]	-8	hSpCas9	negative selection	4682256
112450414	112450436	12	-	27760321	HL60	viability	GTGATGTTCCATGTAATACTGG	PTPN11	ENSG00000179295	-4.58475521493429	[36,48]	[0,1]	-9	hSpCas9	negative selection	4682257
112454568	112454590	12	+	27760321	HL60	viability	TGAAATACGACGTTGGTGGAGG	PTPN11	ENSG00000179295	0.4565403066775508	[408,386]	[515,372]	5	hSpCas9	negative selection	4682258
112454660	112454682	12	+	27760321	HL60	viability	ACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	0.5372511067488615	[271,231]	[256,340]	6	hSpCas9	negative selection	4682259
112477644	112477666	12	+	27760321	HL60	viability	CTTCTAGTTGATCATACCAGGG	PTPN11	ENSG00000179295	-0.3030558697527994	[181,164]	[140,86]	-3	hSpCas9	negative selection	4682260
112446356	112446378	12	+	27760321	HT1080	viability	GGCCTAGTAAAAGTAACCCTGG	PTPN11	ENSG00000179295	1.4335323930028385	[108,84]	[69,141]	7	hSpCas9	negative selection	4765719
112450414	112450436	12	-	27760321	HT1080	viability	GTGATGTTCCATGTAATACTGG	PTPN11	ENSG00000179295	0.46515869482574246	[48,37]	[0,48]	2	hSpCas9	negative selection	4765720
112454568	112454590	12	+	27760321	HT1080	viability	TGAAATACGACGTTGGTGGAGG	PTPN11	ENSG00000179295	-1.583211877748241	[386,301]	[9,84]	-5	hSpCas9	negative selection	4765721
112454660	112454682	12	+	27760321	HT1080	viability	ACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-2.4445728014619768	[231,180]	[27,0]	-7	hSpCas9	negative selection	4765722
112477644	112477666	12	+	27760321	HT1080	viability	CTTCTAGTTGATCATACCAGGG	PTPN11	ENSG00000179295	-1.2708023237348263	[164,128]	[29,17]	-5	hSpCas9	negative selection	4765723
112446356	112446378	12	+	27760321	HT29	viability after 7 days	GGCCTAGTAAAAGTAACCCTGG	PTPN11	ENSG00000179295	-0.603278107886501	[108,84]	[215,22,27]	-7	hSpCas9	negative selection	4849182
112450414	112450436	12	-	27760321	HT29	viability after 7 days	GTGATGTTCCATGTAATACTGG	PTPN11	ENSG00000179295	-0.28008296465256555	[48,37]	[72,25,42]	-4	hSpCas9	negative selection	4849183
112454568	112454590	12	+	27760321	HT29	viability after 7 days	TGAAATACGACGTTGGTGGAGG	PTPN11	ENSG00000179295	-0.20732876128333655	[386,301]	[488,280,394]	-3	hSpCas9	negative selection	4849184
112454660	112454682	12	+	27760321	HT29	viability after 7 days	ACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.5743805006092202	[231,180]	[81,199,236]	-7	hSpCas9	negative selection	4849185
112477644	112477666	12	+	27760321	HT29	viability after 7 days	CTTCTAGTTGATCATACCAGGG	PTPN11	ENSG00000179295	-0.3585736654355296	[164,128]	[159,172,111]	-5	hSpCas9	negative selection	4849186
112446356	112446378	12	+	27760321	HT29	viability after 25 days	GGCCTAGTAAAAGTAACCCTGG	PTPN11	ENSG00000179295	-0.6922161692191455	[108,84]	[95,21,87]	-5	hSpCas9	negative selection	4932645
112450414	112450436	12	-	27760321	HT29	viability after 25 days	GTGATGTTCCATGTAATACTGG	PTPN11	ENSG00000179295	-5.634240282688678	[48,37]	[0,0,0]	-9	hSpCas9	negative selection	4932646
112454568	112454590	12	+	27760321	HT29	viability after 25 days	TGAAATACGACGTTGGTGGAGG	PTPN11	ENSG00000179295	-0.7642215149485123	[386,301]	[211,142,353]	-6	hSpCas9	negative selection	4932647
112454660	112454682	12	+	27760321	HT29	viability after 25 days	ACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-1.1730628449996512	[231,180]	[114,68,131]	-7	hSpCas9	negative selection	4932648
112477644	112477666	12	+	27760321	HT29	viability after 25 days	CTTCTAGTTGATCATACCAGGG	PTPN11	ENSG00000179295	-1.425708178053172	[164,128]	[13,75,104]	-7	hSpCas9	negative selection	4932649
112446356	112446378	12	+	27760321	HT29	viability after 22 days	GGCCTAGTAAAAGTAACCCTGG	PTPN11	ENSG00000179295	0.385659399456342	[108,84]	[298,26,108]	4	hSpCas9	negative selection	5016108
112450414	112450436	12	-	27760321	HT29	viability after 22 days	GTGATGTTCCATGTAATACTGG	PTPN11	ENSG00000179295	-4.655759974333583	[48,37]	[0,3,0]	-9	hSpCas9	negative selection	5016109
112454568	112454590	12	+	27760321	HT29	viability after 22 days	TGAAATACGACGTTGGTGGAGG	PTPN11	ENSG00000179295	-0.3524202850928191	[386,301]	[368,176,388]	-3	hSpCas9	negative selection	5016110
112454660	112454682	12	+	27760321	HT29	viability after 22 days	ACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.8275996291678951	[231,180]	[128,105,168]	-6	hSpCas9	negative selection	5016111
112477644	112477666	12	+	27760321	HT29	viability after 22 days	CTTCTAGTTGATCATACCAGGG	PTPN11	ENSG00000179295	-1.2514738658453353	[164,128]	[17,83,113]	-7	hSpCas9	negative selection	5016112
112446356	112446378	12	+	27760321	HT29	viability after 19 days	GGCCTAGTAAAAGTAACCCTGG	PTPN11	ENSG00000179295	0.7848875110957378	[108,84]	[148,71,341]	7	hSpCas9	negative selection	5099571
112450414	112450436	12	-	27760321	HT29	viability after 19 days	GTGATGTTCCATGTAATACTGG	PTPN11	ENSG00000179295	-5.2126011032772865	[48,37]	[0,1,0]	-9	hSpCas9	negative selection	5099572
112454568	112454590	12	+	27760321	HT29	viability after 19 days	TGAAATACGACGTTGGTGGAGG	PTPN11	ENSG00000179295	-0.41678492484964413	[386,301]	[286,372,226]	-4	hSpCas9	negative selection	5099573
112454660	112454682	12	+	27760321	HT29	viability after 19 days	ACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.3223760183729918	[231,180]	[166,68,322]	-3	hSpCas9	negative selection	5099574
112477644	112477666	12	+	27760321	HT29	viability after 19 days	CTTCTAGTTGATCATACCAGGG	PTPN11	ENSG00000179295	-3.866038777915143	[164,128]	[0,7,23]	-9	hSpCas9	negative selection	5099575
112446356	112446378	12	+	27760321	HT29	viability after 16 days	GGCCTAGTAAAAGTAACCCTGG	PTPN11	ENSG00000179295	-0.868999437338327	[108,84]	[40,1,134]	-6	hSpCas9	negative selection	5183034
112450414	112450436	12	-	27760321	HT29	viability after 16 days	GTGATGTTCCATGTAATACTGG	PTPN11	ENSG00000179295	-5.6042544097038025	[48,37]	[0,0,0]	-9	hSpCas9	negative selection	5183035
112454568	112454590	12	+	27760321	HT29	viability after 16 days	TGAAATACGACGTTGGTGGAGG	PTPN11	ENSG00000179295	-0.6244893982990549	[386,301]	[276,116,361]	-5	hSpCas9	negative selection	5183036
112454660	112454682	12	+	27760321	HT29	viability after 16 days	ACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.39781960014847817	[231,180]	[204,206,115]	-4	hSpCas9	negative selection	5183037
112477644	112477666	12	+	27760321	HT29	viability after 16 days	CTTCTAGTTGATCATACCAGGG	PTPN11	ENSG00000179295	-1.2274708427457433	[164,128]	[18,103,81]	-7	hSpCas9	negative selection	5183038
112446356	112446378	12	+	27760321	HT29	viability after 13 days	GGCCTAGTAAAAGTAACCCTGG	PTPN11	ENSG00000179295	-0.7148243614501664	[108,84]	[75,15,110]	-6	hSpCas9	negative selection	5266497
112450414	112450436	12	-	27760321	HT29	viability after 13 days	GTGATGTTCCATGTAATACTGG	PTPN11	ENSG00000179295	-4.247886290629327	[48,37]	[4,0,1]	-9	hSpCas9	negative selection	5266498
112454568	112454590	12	+	27760321	HT29	viability after 13 days	TGAAATACGACGTTGGTGGAGG	PTPN11	ENSG00000179295	-0.21212772524730722	[386,301]	[399,360,277]	-2	hSpCas9	negative selection	5266499
112454660	112454682	12	+	27760321	HT29	viability after 13 days	ACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.7940113535942683	[231,180]	[72,175,163]	-7	hSpCas9	negative selection	5266500
112477644	112477666	12	+	27760321	HT29	viability after 13 days	CTTCTAGTTGATCATACCAGGG	PTPN11	ENSG00000179295	-1.2590687744782567	[164,128]	[57,87,67]	-8	hSpCas9	negative selection	5266501
112446356	112446378	12	+	27760321	HT29	viability after 10 days	GGCCTAGTAAAAGTAACCCTGG	PTPN11	ENSG00000179295	-0.24072768562686075	[108,84]	[75,44,182]	-3	hSpCas9	negative selection	5349960
112450414	112450436	12	-	27760321	HT29	viability after 10 days	GTGATGTTCCATGTAATACTGG	PTPN11	ENSG00000179295	-3.6513629721607685	[48,37]	[8,2,0]	-9	hSpCas9	negative selection	5349961
112454568	112454590	12	+	27760321	HT29	viability after 10 days	TGAAATACGACGTTGGTGGAGG	PTPN11	ENSG00000179295	-0.45822005489508627	[386,301]	[225,227,478]	-5	hSpCas9	negative selection	5349962
112454660	112454682	12	+	27760321	HT29	viability after 10 days	ACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.052117761679796426	[231,180]	[235,354,159]	0	hSpCas9	negative selection	5349963
112477644	112477666	12	+	27760321	HT29	viability after 10 days	CTTCTAGTTGATCATACCAGGG	PTPN11	ENSG00000179295	-0.6633197365408507	[164,128]	[265,54,26]	-6	hSpCas9	negative selection	5349964
112446356	112446378	12	+	27760321	MOLM13	viability	GGCCTAGTAAAAGTAACCCTGG	PTPN11	ENSG00000179295	-3.685324268769877	[134,108]	[0,8]	-9	hSpCas9	negative selection	5433423
112450414	112450436	12	-	27760321	MOLM13	viability	GTGATGTTCCATGTAATACTGG	PTPN11	ENSG00000179295	-4.621636646723854	[36,48]	[0,0]	-9	hSpCas9	negative selection	5433424
112454568	112454590	12	+	27760321	MOLM13	viability	TGAAATACGACGTTGGTGGAGG	PTPN11	ENSG00000179295	-2.5994589228857947	[408,386]	[8,60]	-8	hSpCas9	negative selection	5433425
112454660	112454682	12	+	27760321	MOLM13	viability	ACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-1.9092003973087386	[271,231]	[0,68]	-8	hSpCas9	negative selection	5433426
112477644	112477666	12	+	27760321	MOLM13	viability	CTTCTAGTTGATCATACCAGGG	PTPN11	ENSG00000179295	-0.7476318410061509	[181,164]	[0,106]	-4	hSpCas9	negative selection	5433427
112419104	112419127	12	+	27661255	K562	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-0.17641999189274093	[1388,1474]	[1110,925]	-5	dCas9-KRAB	negative selection	5505216
112419365	112419388	12	+	27661255	K562	viability	GGGGATGCCCGTCAGGCCCGGGG	PTPN11	ENSG00000179295	0.1079087600685591	[1745,1975]	[1774,1447]	4	dCas9-KRAB	negative selection	5505217
112419402	112419425	12	+	27661255	K562	viability	GAGGGAACCACGGGTGCCAGCGG	PTPN11	ENSG00000179295	0.34224870777971483	[704,856]	[887,702]	9	dCas9-KRAB	negative selection	5505218
112419336	112419359	12	-	27661255	K562	viability	GCCGCAGCCGGAACTCGGGGAGG	PTPN11	ENSG00000179295	0.07256973402035027	[470,529]	[506,344]	2	dCas9-KRAB	negative selection	5505219
112419361	112419384	12	-	27661255	K562	viability	GGGCCTGACGGGCATCCCCGGGG	PTPN11	ENSG00000179295	0.32735971135995834	[711,899]	[818,791]	9	dCas9-KRAB	negative selection	5505220
112446377	112446400	12	+	27260156	BXPC3	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.26728681563358014	[527]	[555,607,747,770]	6	hSpCas9	negative selection	5565525
112454659	112454682	12	+	27260156	BXPC3	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.14171250104985322	[727]	[685,639,654,788]	-3	hSpCas9	negative selection	5565526
112450499	112450522	12	-	27260156	BXPC3	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.5189410465406136	[259]	[362,277,508,420]	9	hSpCas9	negative selection	5565527
112450491	112450514	12	+	27260156	BXPC3	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-0.1641510580793022	[78]	[102,36,41,115]	-4	hSpCas9	negative selection	5629784
112454561	112454584	12	+	27260156	BXPC3	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.6435260147432179	[468]	[258,250,354,410]	-8	hSpCas9	negative selection	5629785
112446373	112446396	12	-	27260156	BXPC3	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	0.03092808996230191	[443]	[424,465,541,466]	0	hSpCas9	negative selection	5629786
112446377	112446400	12	+	27260156	A673	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.05313446642288244	[527]	[701,647,647,635]	1	hSpCas9	negative selection	5686776
112454659	112454682	12	+	27260156	A673	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.5053763828387832	[727]	[717,561,703,482]	-8	hSpCas9	negative selection	5686777
112450499	112450522	12	-	27260156	A673	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.24178810026205833	[259]	[391,329,261,503]	6	hSpCas9	negative selection	5686778
112450491	112450514	12	+	27260156	A673	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	0.04131845109220844	[78]	[90,88,105,103]	1	hSpCas9	negative selection	5751035
112454561	112454584	12	+	27260156	A673	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.5311731123485671	[468]	[513,380,353,319]	-8	hSpCas9	negative selection	5751036
112446373	112446396	12	-	27260156	A673	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.1452200559132843	[443]	[547,484,513,381]	-4	hSpCas9	negative selection	5751037
112446377	112446400	12	+	27260156	A375	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.4021921685900527	[527]	[887,827,939,625]	6	hSpCas9	negative selection	5808027
112454659	112454682	12	+	27260156	A375	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.2017640323290142	[727]	[587,944,802,655]	-3	hSpCas9	negative selection	5808028
112450499	112450522	12	-	27260156	A375	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.2854261897728184	[259]	[435,399,363,292]	4	hSpCas9	negative selection	5808029
112450491	112450514	12	+	27260156	A375	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-0.17700865291882373	[78]	[97,30,87,99]	-3	hSpCas9	negative selection	5872286
112454561	112454584	12	+	27260156	A375	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-1.5201732442850031	[468]	[136,232,247,154]	-9	hSpCas9	negative selection	5872287
112446373	112446396	12	-	27260156	A375	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	0.014337278265259629	[443]	[500,576,606,426]	0	hSpCas9	negative selection	5872288
112446377	112446400	12	+	27260156	COLO741	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.40279193793805523	[527]	[1122,777,798]	7	hSpCas9	negative selection	5929278
112454659	112454682	12	+	27260156	COLO741	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.41566087606160596	[727]	[855,695,561]	-7	hSpCas9	negative selection	5929279
112450499	112450522	12	-	27260156	COLO741	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.056036167912769	[259]	[406,365,272]	1	hSpCas9	negative selection	5929280
112450491	112450514	12	+	27260156	COLO741	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-0.16123664303006757	[78]	[93,87,88]	-3	hSpCas9	negative selection	5993537
112454561	112454584	12	+	27260156	COLO741	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.30669885500495986	[468]	[379,610,454]	-6	hSpCas9	negative selection	5993538
112446373	112446396	12	-	27260156	COLO741	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.22428086604805392	[443]	[573,457,434]	-5	hSpCas9	negative selection	5993539
112446377	112446400	12	+	27260156	CAL120	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.6037763749672111	[527]	[206,457,594]	-7	hSpCas9	negative selection	6050529
112454659	112454682	12	+	27260156	CAL120	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-1.8833505296861441	[727]	[193,132,398]	-9	hSpCas9	negative selection	6050530
112450499	112450522	12	-	27260156	CAL120	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.5899153808726403	[259]	[280,118,253]	-7	hSpCas9	negative selection	6050531
112450491	112450514	12	+	27260156	CAL120	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-1.9985859977578815	[78]	[26,13,32]	-9	hSpCas9	negative selection	6114788
112454561	112454584	12	+	27260156	CAL120	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-1.7531514209648182	[468]	[140,172,199]	-9	hSpCas9	negative selection	6114789
112446373	112446396	12	-	27260156	CAL120	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.6114643397710209	[443]	[387,242,455]	-7	hSpCas9	negative selection	6114790
112446377	112446400	12	+	27260156	CADOES1	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.1157535577234953	[527]	[599,431,465,308]	-2	hSpCas9	negative selection	6171780
112454659	112454682	12	+	27260156	CADOES1	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.4257293166133497	[727]	[585,355,536,537]	-6	hSpCas9	negative selection	6171781
112450499	112450522	12	-	27260156	CADOES1	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.4078820366559105	[259]	[390,349,302,235]	6	hSpCas9	negative selection	6171782
112450491	112450514	12	+	27260156	CADOES1	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-0.1990583417381493	[78]	[59,83,49,61]	-3	hSpCas9	negative selection	6236039
112454561	112454584	12	+	27260156	CADOES1	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.545598780949699	[468]	[257,283,339,313]	-7	hSpCas9	negative selection	6236040
112446373	112446396	12	-	27260156	CADOES1	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.22780745202057517	[443]	[437,292,330,347]	-4	hSpCas9	negative selection	6236041
112446377	112446400	12	+	27260156	EWS502	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.002238223040694598	[527]	[425,541,697,585]	0	hSpCas9	negative selection	6293031
112454659	112454682	12	+	27260156	EWS502	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.5120553971079574	[727]	[613,295,619,639]	-7	hSpCas9	negative selection	6293032
112450499	112450522	12	-	27260156	EWS502	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.37889662338841096	[259]	[291,382,351,414]	6	hSpCas9	negative selection	6293033
112450491	112450514	12	+	27260156	EWS502	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-0.06268517997306988	[78]	[89,54,65,110]	-1	hSpCas9	negative selection	6357290
112454561	112454584	12	+	27260156	EWS502	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.8382839443119611	[468]	[380,264,137,314]	-8	hSpCas9	negative selection	6357291
112446373	112446396	12	-	27260156	EWS502	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	0.014247626823145176	[443]	[466,366,450,628]	0	hSpCas9	negative selection	6357292
112446377	112446400	12	+	27260156	EW8	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.10415711456773186	[527]	[416,328,366,484]	-2	hSpCas9	negative selection	6414282
112454659	112454682	12	+	27260156	EW8	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.3702926732512341	[727]	[613,469,331,446]	-6	hSpCas9	negative selection	6414283
112450499	112450522	12	-	27260156	EW8	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.014445436047609728	[259]	[226,221,190,215]	0	hSpCas9	negative selection	6414284
112450491	112450514	12	+	27260156	EW8	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-1.1700396194513054	[78]	[38,50,16,9]	-9	hSpCas9	negative selection	6478541
112454561	112454584	12	+	27260156	EW8	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.848817852161659	[468]	[191,224,183,244]	-9	hSpCas9	negative selection	6478542
112446373	112446396	12	-	27260156	EW8	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.01723441192811491	[443]	[435,332,313,353]	0	hSpCas9	negative selection	6478543
112446377	112446400	12	+	27260156	CORL105	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.46129418719501303	[527]	[506,381,542,381]	-7	hSpCas9	negative selection	6535533
112454659	112454682	12	+	27260156	CORL105	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.8757056312321643	[727]	[530,419,470,439]	-9	hSpCas9	negative selection	6535534
112450499	112450522	12	-	27260156	CORL105	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.4435155878052499	[259]	[345,177,244,134]	-7	hSpCas9	negative selection	6535535
112450491	112450514	12	+	27260156	CORL105	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-1.2518855551630623	[78]	[73,34,27,17]	-9	hSpCas9	negative selection	6599792
112454561	112454584	12	+	27260156	CORL105	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-1.319059585807445	[468]	[229,183,256,215]	-9	hSpCas9	negative selection	6599793
112446373	112446396	12	-	27260156	CORL105	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.17452445699923047	[443]	[393,453,612,402]	-3	hSpCas9	negative selection	6599794
112446377	112446400	12	+	27260156	HS294T	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.009871030833867922	[527]	[231,147,219,223]	0	hSpCas9	negative selection	6656784
112454659	112454682	12	+	27260156	HS294T	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.3814141113060303	[727]	[254,147,183,286]	-5	hSpCas9	negative selection	6656785
112450499	112450522	12	-	27260156	HS294T	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.0933455293047496	[259]	[52,62,144,125]	-1	hSpCas9	negative selection	6656786
112450491	112450514	12	+	27260156	HS294T	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-1.0186613738573498	[78]	[18,10,9,20]	-9	hSpCas9	negative selection	6721043
112454561	112454584	12	+	27260156	HS294T	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-1.1539422274040332	[468]	[61,52,69,155]	-9	hSpCas9	negative selection	6721044
112446373	112446396	12	-	27260156	HS294T	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.14105247178311747	[443]	[154,111,169,192]	-2	hSpCas9	negative selection	6721045
112446377	112446400	12	+	27260156	HCC44	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.09774403983193099	[527]	[580,514,602,544]	-2	hSpCas9	negative selection	6778035
112454659	112454682	12	+	27260156	HCC44	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.874148423389681	[727]	[543,367,492,416]	-8	hSpCas9	negative selection	6778036
112450499	112450522	12	-	27260156	HCC44	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.3168696315228876	[259]	[281,181,317,187]	-5	hSpCas9	negative selection	6778037
112450491	112450514	12	+	27260156	HCC44	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-1.0451513964501151	[78]	[52,38,60,24]	-8	hSpCas9	negative selection	6842294
112454561	112454584	12	+	27260156	HCC44	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-1.066681556972918	[468]	[190,339,226,230]	-8	hSpCas9	negative selection	6842295
112446373	112446396	12	-	27260156	HCC44	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.5939282617955978	[443]	[373,232,529,245]	-7	hSpCas9	negative selection	6842296
112446377	112446400	12	+	27260156	G402	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.614656288598951	[527]	[670,469,255,327]	-6	hSpCas9	negative selection	6899286
112454659	112454682	12	+	27260156	G402	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-1.3260794656420394	[727]	[522,192,427,289]	-9	hSpCas9	negative selection	6899287
112450499	112450522	12	-	27260156	G402	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.31734099232303636	[259]	[88,497,299,126]	-4	hSpCas9	negative selection	6899288
112450491	112450514	12	+	27260156	G402	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-3.236825794554551	[78]	[7,4,11,14]	-9	hSpCas9	negative selection	6963545
112454561	112454584	12	+	27260156	G402	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-1.7876163632315736	[468]	[118,219,221,100]	-9	hSpCas9	negative selection	6963546
112446373	112446396	12	-	27260156	G402	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.1832316412136769	[443]	[469,564,465,412]	-2	hSpCas9	negative selection	6963547
112446377	112446400	12	+	27260156	L33	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.21844662034996917	[527]	[697,247,326,630]	5	hSpCas9	negative selection	7020537
112454659	112454682	12	+	27260156	L33	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.0777015995222492	[727]	[694,328,357,690]	-2	hSpCas9	negative selection	7020538
112450499	112450522	12	-	27260156	L33	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.3293967721067306	[259]	[408,135,203,239]	7	hSpCas9	negative selection	7020539
112450491	112450514	12	+	27260156	L33	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	0.1295020585054445	[78]	[136,24,49,66]	3	hSpCas9	negative selection	7084796
112454561	112454584	12	+	27260156	L33	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.7899184972386311	[468]	[275,88,114,406]	-9	hSpCas9	negative selection	7084797
112446373	112446396	12	-	27260156	L33	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.20370454771378088	[443]	[499,121,230,373]	-5	hSpCas9	negative selection	7084798
112446377	112446400	12	+	27260156	K562	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-1.154705677497479	[527]	[270,291,159,135]	-8	hSpCas9	negative selection	7141788
112454659	112454682	12	+	27260156	K562	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-1.4171680323844296	[727]	[243,229,361,141]	-9	hSpCas9	negative selection	7141789
112450499	112450522	12	-	27260156	K562	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-1.0379934324057465	[259]	[183,178,73,30]	-8	hSpCas9	negative selection	7141790
112450491	112450514	12	+	27260156	K562	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-2.8103767460792057	[78]	[0,2,16,16]	-9	hSpCas9	negative selection	7206047
112454561	112454584	12	+	27260156	K562	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-3.3055075967569283	[468]	[33,26,65,39]	-9	hSpCas9	negative selection	7206048
112446373	112446396	12	-	27260156	K562	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.7392298684544207	[443]	[536,172,145,121]	-7	hSpCas9	negative selection	7206049
112446377	112446400	12	+	27260156	HT29	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.3331236340275603	[527]	[692,835,930,766]	6	hSpCas9	negative selection	7263039
112454659	112454682	12	+	27260156	HT29	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.5244566908506493	[727]	[682,613,570,595]	-7	hSpCas9	negative selection	7263040
112450499	112450522	12	-	27260156	HT29	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.3441042035431091	[259]	[384,381,484,352]	6	hSpCas9	negative selection	7263041
112450491	112450514	12	+	27260156	HT29	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-0.45132001617312145	[78]	[118,64,13,83]	-7	hSpCas9	negative selection	7327298
112454561	112454584	12	+	27260156	HT29	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.9142298310302859	[468]	[407,260,281,265]	-8	hSpCas9	negative selection	7327299
112446373	112446396	12	-	27260156	HT29	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	0.01872792393261695	[443]	[686,440,663,409]	0	hSpCas9	negative selection	7327300
112446377	112446400	12	+	27260156	MHHES1	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.13624209258026113	[527]	[919,549,366,394]	-3	hSpCas9	negative selection	7384290
112454659	112454682	12	+	27260156	MHHES1	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.5878529935072552	[727]	[746,707,480,325]	-8	hSpCas9	negative selection	7384291
112450499	112450522	12	-	27260156	MHHES1	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.06895084111628735	[259]	[362,404,236,246]	1	hSpCas9	negative selection	7384292
112450491	112450514	12	+	27260156	MHHES1	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-0.3238317339696657	[78]	[76,104,70,40]	-6	hSpCas9	negative selection	7448549
112454561	112454584	12	+	27260156	MHHES1	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.9381214010182624	[468]	[292,274,283,251]	-9	hSpCas9	negative selection	7448550
112446373	112446396	12	-	27260156	MHHES1	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.131712577342116	[443]	[535,557,516,268]	-2	hSpCas9	negative selection	7448551
112446377	112446400	12	+	27260156	MEWO	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.19452028978192584	[527]	[484,480,338]	-4	hSpCas9	negative selection	7505541
112454659	112454682	12	+	27260156	MEWO	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.6165728652402411	[727]	[534,473,340]	-8	hSpCas9	negative selection	7505542
112450499	112450522	12	-	27260156	MEWO	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.2089266102009033	[259]	[375,232,252]	4	hSpCas9	negative selection	7505543
112450491	112450514	12	+	27260156	MEWO	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-1.7192839058859168	[78]	[25,26,14]	-9	hSpCas9	negative selection	7569800
112454561	112454584	12	+	27260156	MEWO	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.6273984273931644	[468]	[368,184,314]	-8	hSpCas9	negative selection	7569801
112446373	112446396	12	-	27260156	MEWO	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.4167057105439238	[443]	[457,294,208]	-7	hSpCas9	negative selection	7569802
112446377	112446400	12	+	27260156	LNCAPCLONEFGC	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.13790851476478924	[527]	[493,380,748,523]	2	hSpCas9	negative selection	7626792
112454659	112454682	12	+	27260156	LNCAPCLONEFGC	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.0891227428088811	[727]	[658,438,817,603]	-1	hSpCas9	negative selection	7626793
112450499	112450522	12	-	27260156	LNCAPCLONEFGC	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.33723085642603834	[259]	[254,248,465,248]	5	hSpCas9	negative selection	7626794
112450491	112450514	12	+	27260156	LNCAPCLONEFGC	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-1.1822877399550387	[78]	[43,24,15,38]	-9	hSpCas9	negative selection	7691051
112454561	112454584	12	+	27260156	LNCAPCLONEFGC	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.8222352331965146	[468]	[207,305,231,209]	-8	hSpCas9	negative selection	7691052
112446373	112446396	12	-	27260156	LNCAPCLONEFGC	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.026184289516089185	[443]	[312,316,641,350]	0	hSpCas9	negative selection	7691053
112446377	112446400	12	+	27260156	PANC0327	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.8225025896602006	[527]	[384,183,221,289]	-8	hSpCas9	negative selection	7748043
112454659	112454682	12	+	27260156	PANC0327	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.8902481483715732	[727]	[446,211,273,487]	-8	hSpCas9	negative selection	7748044
112450499	112450522	12	-	27260156	PANC0327	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.492580792049814	[259]	[256,103,179,130]	-6	hSpCas9	negative selection	7748045
112450491	112450514	12	+	27260156	PANC0327	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-2.403926185866856	[78]	[34,3,4,11]	-9	hSpCas9	negative selection	7812302
112454561	112454584	12	+	27260156	PANC0327	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-1.6156155849438172	[468]	[233,125,73,118]	-9	hSpCas9	negative selection	7812303
112446373	112446396	12	-	27260156	PANC0327	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	0.14805144700167774	[443]	[348,353,273,773]	2	hSpCas9	negative selection	7812304
112446377	112446400	12	+	27260156	NCIH2009	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.9004869492557962	[527]	[469,487,239]	-8	hSpCas9	negative selection	7869294
112454659	112454682	12	+	27260156	NCIH2009	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-1.2168600482617755	[727]	[680,499,177]	-8	hSpCas9	negative selection	7869295
112450499	112450522	12	-	27260156	NCIH2009	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.5348969079411103	[259]	[304,221,235]	-6	hSpCas9	negative selection	7869296
112450491	112450514	12	+	27260156	NCIH2009	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-1.9579919633135243	[78]	[41,20,24]	-9	hSpCas9	negative selection	7933553
112454561	112454584	12	+	27260156	NCIH2009	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-1.8762679323995002	[468]	[299,132,126]	-9	hSpCas9	negative selection	7933554
112446373	112446396	12	-	27260156	NCIH2009	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.4513157582363887	[443]	[439,542,372]	-5	hSpCas9	negative selection	7933555
112446377	112446400	12	+	27260156	NCIH1373	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.4293095871748547	[527]	[593,377,412,104]	-4	hSpCas9	negative selection	7990545
112454659	112454682	12	+	27260156	NCIH1373	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.5424314538517098	[727]	[721,440,182,252]	-5	hSpCas9	negative selection	7990546
112450499	112450522	12	-	27260156	NCIH1373	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.21345457885837038	[259]	[131,333,230,73]	-2	hSpCas9	negative selection	7990547
112450491	112450514	12	+	27260156	NCIH1373	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-2.502449689189555	[78]	[6,5,15,8]	-9	hSpCas9	negative selection	8054804
112454561	112454584	12	+	27260156	NCIH1373	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-1.2891741966711974	[468]	[248,120,401,23]	-8	hSpCas9	negative selection	8054805
112446373	112446396	12	-	27260156	NCIH1373	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.14060843707085746	[443]	[711,293,462,101]	-1	hSpCas9	negative selection	8054806
112446377	112446400	12	+	27260156	PATU8902	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.4127644299074087	[527]	[443,494,659,582]	-4	hSpCas9	negative selection	8111796
112454659	112454682	12	+	27260156	PATU8902	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.9155092083204457	[727]	[218,837,526,573]	-7	hSpCas9	negative selection	8111797
112450499	112450522	12	-	27260156	PATU8902	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-1.469601465792407	[259]	[112,176,61,195]	-8	hSpCas9	negative selection	8111798
112450491	112450514	12	+	27260156	PATU8902	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-1.1725204537891125	[78]	[141,34,12,7]	-8	hSpCas9	negative selection	8176055
112454561	112454584	12	+	27260156	PATU8902	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-3.2458548926804767	[468]	[93,108,30,47]	-9	hSpCas9	negative selection	8176056
112446373	112446396	12	-	27260156	PATU8902	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	0.04321832130153735	[443]	[751,763,545,485]	0	hSpCas9	negative selection	8176057
112446377	112446400	12	+	27260156	PANC1	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.25298333630545616	[527]	[393,521,408,242]	-4	hSpCas9	negative selection	8233047
112454659	112454682	12	+	27260156	PANC1	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.449681084837656	[727]	[468,539,388,443]	-6	hSpCas9	negative selection	8233048
112450499	112450522	12	-	27260156	PANC1	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.1470152695912328	[259]	[290,279,154,106]	-2	hSpCas9	negative selection	8233049
112450491	112450514	12	+	27260156	PANC1	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-1.9459680106512578	[78]	[6,13,45,4]	-9	hSpCas9	negative selection	8297306
112454561	112454584	12	+	27260156	PANC1	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-1.139173610908589	[468]	[221,137,278,94]	-8	hSpCas9	negative selection	8297307
112446373	112446396	12	-	27260156	PANC1	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.1505339847809045	[443]	[331,442,272,340]	-2	hSpCas9	negative selection	8297308
112446377	112446400	12	+	27260156	PANC0813	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.3643594395561365	[527]	[590,582,306,455]	-5	hSpCas9	negative selection	8354298
112454659	112454682	12	+	27260156	PANC0813	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.48135091870705293	[727]	[689,625,494,642]	-6	hSpCas9	negative selection	8354299
112450499	112450522	12	-	27260156	PANC0813	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.009791121909447087	[259]	[345,239,293,334]	0	hSpCas9	negative selection	8354300
112450491	112450514	12	+	27260156	PANC0813	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	0.28362057024138565	[78]	[128,102,174,49]	4	hSpCas9	negative selection	8418557
112454561	112454584	12	+	27260156	PANC0813	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-1.2652820055632341	[468]	[252,185,289,191]	-9	hSpCas9	negative selection	8418558
112446373	112446396	12	-	27260156	PANC0813	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.17770724500532203	[443]	[438,427,378,587]	-3	hSpCas9	negative selection	8418559
112446377	112446400	12	+	27260156	RDES	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.0047187775113013974	[527]	[479,622,571,777]	0	hSpCas9	negative selection	8475549
112454659	112454682	12	+	27260156	RDES	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.5418669412182113	[727]	[478,551,603,688]	-7	hSpCas9	negative selection	8475550
112450499	112450522	12	-	27260156	RDES	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.18915718341312449	[259]	[305,251,359,471]	3	hSpCas9	negative selection	8475551
112450491	112450514	12	+	27260156	RDES	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-0.9013129926681418	[78]	[39,55,50,46]	-9	hSpCas9	negative selection	8539808
112454561	112454584	12	+	27260156	RDES	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-1.0956047608324044	[468]	[181,259,225,364]	-9	hSpCas9	negative selection	8539809
112446373	112446396	12	-	27260156	RDES	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.000577891268403144	[443]	[519,433,533,547]	0	hSpCas9	negative selection	8539810
112446377	112446400	12	+	27260156	PC3	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.30775524022039213	[527]	[295,588,1211,847]	6	hSpCas9	negative selection	8596800
112454659	112454682	12	+	27260156	PC3	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.12918325758877558	[727]	[529,467,948,814]	-3	hSpCas9	negative selection	8596801
112450499	112450522	12	-	27260156	PC3	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.236950706509238	[259]	[145,351,338,446]	5	hSpCas9	negative selection	8596802
112450491	112450514	12	+	27260156	PC3	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-1.0514030305799862	[78]	[27,57,42,22]	-9	hSpCas9	negative selection	8661059
112454561	112454584	12	+	27260156	PC3	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.7306723809536996	[468]	[156,230,522,345]	-9	hSpCas9	negative selection	8661060
112446373	112446396	12	-	27260156	PC3	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	0.1348392872038497	[443]	[205,432,856,693]	3	hSpCas9	negative selection	8661061
112446377	112446400	12	+	27260156	PATU8988T	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.24612233027501357	[527]	[436,460,356,472]	-4	hSpCas9	negative selection	8718051
112454659	112454682	12	+	27260156	PATU8988T	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-1.2281426511162352	[727]	[288,358,279,276]	-9	hSpCas9	negative selection	8718052
112450499	112450522	12	-	27260156	PATU8988T	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.25035272654664364	[259]	[327,146,90,279]	-4	hSpCas9	negative selection	8718053
112450491	112450514	12	+	27260156	PATU8988T	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-0.3750655859430605	[78]	[74,38,26,95]	-6	hSpCas9	negative selection	8782310
112454561	112454584	12	+	27260156	PATU8988T	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.7008614677817957	[468]	[188,217,406,294]	-8	hSpCas9	negative selection	8782311
112446373	112446396	12	-	27260156	PATU8988T	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	0.0020720286750740002	[443]	[723,422,319,236]	0	hSpCas9	negative selection	8782312
112446377	112446400	12	+	27260156	T47D	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.08229578972648312	[527]	[593,501,624,609]	-2	hSpCas9	negative selection	8839302
112454659	112454682	12	+	27260156	T47D	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.4831658143497469	[727]	[563,634,555,671]	-7	hSpCas9	negative selection	8839303
112450499	112450522	12	-	27260156	T47D	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.1576938659808511	[259]	[275,308,372,396]	3	hSpCas9	negative selection	8839304
112450491	112450514	12	+	27260156	T47D	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-0.7491921314985652	[78]	[51,58,65,40]	-9	hSpCas9	negative selection	8903561
112454561	112454584	12	+	27260156	T47D	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.7545221534432552	[468]	[251,331,351,358]	-9	hSpCas9	negative selection	8903562
112446373	112446396	12	-	27260156	T47D	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.14686041034644182	[443]	[496,321,580,479]	-3	hSpCas9	negative selection	8903563
112446377	112446400	12	+	27260156	SU8686	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.05374944054329281	[527]	[514,465,598,615]	0	hSpCas9	negative selection	8960553
112454659	112454682	12	+	27260156	SU8686	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	0.051908919685172084	[727]	[663,582,864,940]	0	hSpCas9	negative selection	8960554
112450499	112450522	12	-	27260156	SU8686	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.024934903037680756	[259]	[184,278,251,308]	0	hSpCas9	negative selection	8960555
112450491	112450514	12	+	27260156	SU8686	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	0.43904358005867605	[78]	[55,81,154,147]	7	hSpCas9	negative selection	9024812
112454561	112454584	12	+	27260156	SU8686	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.834053002074149	[468]	[303,190,298,250]	-8	hSpCas9	negative selection	9024813
112446373	112446396	12	-	27260156	SU8686	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.12649639465124937	[443]	[245,383,347,698]	-2	hSpCas9	negative selection	9024814
112446377	112446400	12	+	27260156	SKES1	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.2584613810055113	[527]	[542,558,362,333]	-5	hSpCas9	negative selection	9081804
112454659	112454682	12	+	27260156	SKES1	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.5117150561466464	[727]	[627,592,341,498]	-8	hSpCas9	negative selection	9081805
112450499	112450522	12	-	27260156	SKES1	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.15121735082453325	[259]	[452,317,276,144]	3	hSpCas9	negative selection	9081806
112450491	112450514	12	+	27260156	SKES1	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	0.0954028329056924	[78]	[145,104,75,26]	2	hSpCas9	negative selection	9146063
112454561	112454584	12	+	27260156	SKES1	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.3999240337374762	[468]	[222,478,320,384]	-7	hSpCas9	negative selection	9146064
112446373	112446396	12	-	27260156	SKES1	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.3842120897836305	[443]	[322,390,333,312]	-7	hSpCas9	negative selection	9146065
112446377	112446400	12	+	27260156	TOV112D	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.17385145963395246	[527]	[623,507,365,400]	-3	hSpCas9	negative selection	9203055
112454659	112454682	12	+	27260156	TOV112D	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.5168693535178636	[727]	[726,437,538,338]	-8	hSpCas9	negative selection	9203056
112450499	112450522	12	-	27260156	TOV112D	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.00807333852299652	[259]	[390,340,195,141]	0	hSpCas9	negative selection	9203057
112450491	112450514	12	+	27260156	TOV112D	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-1.156587738637008	[78]	[23,53,13,52]	-9	hSpCas9	negative selection	9267314
112454561	112454584	12	+	27260156	TOV112D	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.5567692929459422	[468]	[303,204,296,437]	-8	hSpCas9	negative selection	9267315
112446373	112446396	12	-	27260156	TOV112D	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.14445053800234803	[443]	[578,529,327,222]	-3	hSpCas9	negative selection	9267316
112446377	112446400	12	+	27260156	TC71	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.06858745029590059	[527]	[412,652,446,658]	-2	hSpCas9	negative selection	9324306
112454659	112454682	12	+	27260156	TC71	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.5580271873465259	[727]	[431,663,441,590]	-9	hSpCas9	negative selection	9324307
112450499	112450522	12	-	27260156	TC71	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.056068303836044664	[259]	[261,225,283,301]	-1	hSpCas9	negative selection	9324308
112450491	112450514	12	+	27260156	TC71	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	-0.19301125710623124	[78]	[58,100,72,62]	-5	hSpCas9	negative selection	9388565
112454561	112454584	12	+	27260156	TC71	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-0.8439792175830263	[468]	[224,326,350,211]	-9	hSpCas9	negative selection	9388566
112446373	112446396	12	-	27260156	TC71	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	-0.2619209800689202	[443]	[393,343,370,484]	-6	hSpCas9	negative selection	9388567
112446377	112446400	12	+	27260156	TC32	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.12210712050077069	[527]	[438,304,548,586]	-2	hSpCas9	negative selection	9445557
112454659	112454682	12	+	27260156	TC32	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.49114347297893973	[727]	[439,377,597,572]	-7	hSpCas9	negative selection	9445558
112450499	112450522	12	-	27260156	TC32	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.3197624832545771	[259]	[292,161,485,351]	5	hSpCas9	negative selection	9445559
112450491	112450514	12	+	27260156	TC32	viability	GTGCAGATCCTACCTCTGAAAGG	PTPN11	ENSG00000179295	0.0333123539079061	[78]	[62,49,132,74]	0	hSpCas9	negative selection	9509816
112454561	112454584	12	+	27260156	TC32	viability	AAGGAACTGAAATACGACGTTGG	PTPN11	ENSG00000179295	-1.3514681836863165	[468]	[176,50,291,231]	-9	hSpCas9	negative selection	9509817
112446373	112446396	12	-	27260156	TC32	viability	ACGGAAAGTGTGAAGTCTCCAGG	PTPN11	ENSG00000179295	0.21326976281039306	[443]	[561,281,543,601]	4	hSpCas9	negative selection	9509818
112502243	112502266	12	-	27869803	HPAFII	viability after 27 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-0.8269791998052409	[199]	[79,41,NaN]	-5	hSpCas9	negative selection	9545261
112502246	112502269	12	-	27869803	HPAFII	viability after 27 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-1.0631417320362857	[154]	[68,13,NaN]	-6	hSpCas9	negative selection	9545262
112502243	112502266	12	-	27869803	HPAFII	viability after 15 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-0.085372820849905	[199]	[328,123,NaN]	-1	hSpCas9	negative selection	9627710
112502246	112502269	12	-	27869803	HPAFII	viability after 15 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-0.8934661751639434	[154]	[175,35,NaN]	-7	hSpCas9	negative selection	9627711
112502243	112502266	12	-	27869803	ASPC1	viability after 36 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-0.08449057510443031	[462]	[173,146,139]	-1	hSpCas9	negative selection	9710159
112502246	112502269	12	-	27869803	ASPC1	viability after 36 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	0.04765419439371871	[502]	[535,43,39]	0	hSpCas9	negative selection	9710160
112502243	112502266	12	-	27869803	PATU8988S	viability after 35 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-0.5700342954421644	[491]	[122,143,NaN]	-5	hSpCas9	negative selection	9792608
112502246	112502269	12	-	27869803	PATU8988S	viability after 35 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-0.5876427807453825	[503]	[166,102,NaN]	-5	hSpCas9	negative selection	9792609
112502243	112502266	12	-	27869803	PATU8988S	viability after 31 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-0.25117318047592646	[491]	[137,198,NaN]	-3	hSpCas9	negative selection	9875057
112502246	112502269	12	-	27869803	PATU8988S	viability after 31 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-0.9559514858075221	[503]	[96,111,NaN]	-7	hSpCas9	negative selection	9875058
112502243	112502266	12	-	27869803	HPAFII	viability after 35 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	-0.9112162077152826	[199]	[82,20,NaN]	-5	hSpCas9	negative selection	9957506
112502246	112502269	12	-	27869803	HPAFII	viability after 35 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-1.9593341812067084	[154]	[22,16,NaN]	-7	hSpCas9	negative selection	9957507
112502243	112502266	12	-	27869803	HPAFII	viability after 31 days	ACTACTTACTCTGCACAGGGTGG	PTPN11	ENSG00000179295	0.06874815454505326	[199]	[144,87,NaN]	0	hSpCas9	negative selection	10039955
112502246	112502269	12	-	27869803	HPAFII	viability after 31 days	AGCACTACTTACTCTGCACAGGG	PTPN11	ENSG00000179295	-2.6539183715121735	[154]	[20,5,NaN]	-8	hSpCas9	negative selection	10039956
112419104	112419127	12	+	28162770	P31FUJ	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	1.1492468829105547	[93]	[244]	9	hSpCas9	negative selection	10219755
112502237	112502260	12	-	28162770	P31FUJ	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	0.009768098859699426	[141]	[167]	0	hSpCas9	negative selection	10219756
112486476	112486499	12	+	28162770	P31FUJ	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-1.3703057281643138	[65]	[29]	-7	hSpCas9	negative selection	10219757
112453315	112453338	12	+	28162770	P31FUJ	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	0.07990736044360502	[156]	[194]	0	hSpCas9	negative selection	10219758
112486527	112486550	12	+	28162770	P31FUJ	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.11443279029015785	[598]	[761]	1	hSpCas9	negative selection	10219759
112454659	112454682	12	+	28162770	P31FUJ	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.5568046275395995	[173]	[138]	-5	hSpCas9	negative selection	10219760
112450499	112450522	12	-	28162770	P31FUJ	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.10789277185160384	[386]	[421]	-1	hSpCas9	negative selection	10219761
112456042	112456065	12	+	28162770	P31FUJ	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	0.8106692986557475	[473]	[976]	8	hSpCas9	negative selection	10219762
112446377	112446400	12	+	28162770	P31FUJ	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.47226813910976806	[849]	[719]	-4	hSpCas9	negative selection	10219763
112453301	112453324	12	+	28162770	P31FUJ	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.5934857390037473	[1048]	[1859]	6	hSpCas9	negative selection	10219764
112419104	112419127	12	+	28162770	TF1	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10389121
112502237	112502260	12	-	28162770	TF1	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10389122
112486476	112486499	12	+	28162770	TF1	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10389123
112453315	112453338	12	+	28162770	TF1	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10389124
112486527	112486550	12	+	28162770	TF1	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	NaN	[NaN]	[295]	1	hSpCas9	negative selection	10389125
112454659	112454682	12	+	28162770	TF1	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	NaN	[NaN]	[33]	1	hSpCas9	negative selection	10389126
112450499	112450522	12	-	28162770	TF1	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	NaN	[NaN]	[181]	1	hSpCas9	negative selection	10389127
112456042	112456065	12	+	28162770	TF1	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	NaN	[NaN]	[304]	1	hSpCas9	negative selection	10389128
112446377	112446400	12	+	28162770	TF1	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	NaN	[NaN]	[208]	1	hSpCas9	negative selection	10389129
112453301	112453324	12	+	28162770	TF1	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	NaN	[NaN]	[914]	1	hSpCas9	negative selection	10389130
112419104	112419127	12	+	28162770	SKM1	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	0.3796321631476449	[19]	[45]	3	hSpCas9	negative selection	10558487
112502237	112502260	12	-	28162770	SKM1	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	0.3773071102014012	[26]	[61]	3	hSpCas9	negative selection	10558488
112486476	112486499	12	+	28162770	SKM1	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	0.04473177111453053	[33]	[61]	0	hSpCas9	negative selection	10558489
112453315	112453338	12	+	28162770	SKM1	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	-0.7675539139996294	[51]	[53]	-5	hSpCas9	negative selection	10558490
112486527	112486550	12	+	28162770	SKM1	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.9040531219337502	[145]	[482]	8	hSpCas9	negative selection	10558491
112454659	112454682	12	+	28162770	SKM1	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.373016866819824	[62]	[85]	-3	hSpCas9	negative selection	10558492
112450499	112450522	12	-	28162770	SKM1	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.11240996035041773	[89]	[171]	1	hSpCas9	negative selection	10558493
112456042	112456065	12	+	28162770	SKM1	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	0.5259216053983016	[142]	[363]	5	hSpCas9	negative selection	10558494
112446377	112446400	12	+	28162770	SKM1	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.29626118359781417	[198]	[431]	3	hSpCas9	negative selection	10558495
112453301	112453324	12	+	28162770	SKM1	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.5236424658391641	[180]	[459]	5	hSpCas9	negative selection	10558496
112419104	112419127	12	+	28162770	SKM1	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	0.3796321631476449	[19]	[45]	3	hSpCas9	negative selection	10727853
112502237	112502260	12	-	28162770	SKM1	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	0.3773071102014012	[26]	[61]	3	hSpCas9	negative selection	10727854
112486476	112486499	12	+	28162770	SKM1	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	0.04473177111453053	[33]	[61]	0	hSpCas9	negative selection	10727855
112453315	112453338	12	+	28162770	SKM1	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	-0.7675539139996294	[51]	[53]	-5	hSpCas9	negative selection	10727856
112486527	112486550	12	+	28162770	SKM1	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.9040531219337502	[145]	[482]	8	hSpCas9	negative selection	10727857
112454659	112454682	12	+	28162770	SKM1	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.373016866819824	[62]	[85]	-3	hSpCas9	negative selection	10727858
112450499	112450522	12	-	28162770	SKM1	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.11240996035041773	[89]	[171]	1	hSpCas9	negative selection	10727859
112456042	112456065	12	+	28162770	SKM1	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	0.5259216053983016	[142]	[363]	5	hSpCas9	negative selection	10727860
112446377	112446400	12	+	28162770	SKM1	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.29626118359781417	[198]	[431]	3	hSpCas9	negative selection	10727861
112453301	112453324	12	+	28162770	SKM1	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.5236424658391641	[180]	[459]	5	hSpCas9	negative selection	10727862
112419104	112419127	12	+	28162770	PL21	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-1.500300103651772	[103]	[15]	-7	hSpCas9	negative selection	10897219
112502237	112502260	12	-	28162770	PL21	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	-1.654009519047225	[93]	[12]	-8	hSpCas9	negative selection	10897220
112486476	112486499	12	+	28162770	PL21	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-1.0477878989542655	[94]	[19]	-6	hSpCas9	negative selection	10897221
112453315	112453338	12	+	28162770	PL21	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	-0.3848228862318361	[188]	[62]	-3	hSpCas9	negative selection	10897222
112486527	112486550	12	+	28162770	PL21	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.15879881910842064	[530]	[257]	1	hSpCas9	negative selection	10897223
112454659	112454682	12	+	28162770	PL21	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.590222236654979	[210]	[60]	-4	hSpCas9	negative selection	10897224
112450499	112450522	12	-	28162770	PL21	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.9506403376862889	[261]	[58]	-6	hSpCas9	negative selection	10897225
112456042	112456065	12	+	28162770	PL21	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	0.27039181058641404	[500]	[262]	2	hSpCas9	negative selection	10897226
112446377	112446400	12	+	28162770	PL21	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.2960285355387542	[712]	[380]	2	hSpCas9	negative selection	10897227
112453301	112453324	12	+	28162770	PL21	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.21712696850989266	[590]	[298]	2	hSpCas9	negative selection	10897228
112419104	112419127	12	+	28162770	P31FUJ	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	1.1492468829105547	[93]	[244]	9	hSpCas9	negative selection	11066585
112502237	112502260	12	-	28162770	P31FUJ	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	0.009768098859699426	[141]	[167]	0	hSpCas9	negative selection	11066586
112486476	112486499	12	+	28162770	P31FUJ	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-1.3703057281643138	[65]	[29]	-7	hSpCas9	negative selection	11066587
112453315	112453338	12	+	28162770	P31FUJ	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	0.07990736044360502	[156]	[194]	0	hSpCas9	negative selection	11066588
112486527	112486550	12	+	28162770	P31FUJ	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.11443279029015785	[598]	[761]	1	hSpCas9	negative selection	11066589
112454659	112454682	12	+	28162770	P31FUJ	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.5568046275395995	[173]	[138]	-5	hSpCas9	negative selection	11066590
112450499	112450522	12	-	28162770	P31FUJ	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.10789277185160384	[386]	[421]	-1	hSpCas9	negative selection	11066591
112456042	112456065	12	+	28162770	P31FUJ	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	0.8106692986557475	[473]	[976]	8	hSpCas9	negative selection	11066592
112446377	112446400	12	+	28162770	P31FUJ	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.47226813910976806	[849]	[719]	-4	hSpCas9	negative selection	11066593
112453301	112453324	12	+	28162770	P31FUJ	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.5934857390037473	[1048]	[1859]	6	hSpCas9	negative selection	11066594
112419104	112419127	12	+	28162770	OCIAML5	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-2.7451513669474847	[25]	[6]	-8	hSpCas9	negative selection	11235951
112502237	112502260	12	-	28162770	OCIAML5	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	-0.30927352438678035	[80]	[117]	-2	hSpCas9	negative selection	11235952
112486476	112486499	12	+	28162770	OCIAML5	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-4.021991572306309	[17]	[1]	-9	hSpCas9	negative selection	11235953
112453315	112453338	12	+	28162770	OCIAML5	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	-4.205703525478698	[91]	[8]	-9	hSpCas9	negative selection	11235954
112486527	112486550	12	+	28162770	OCIAML5	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.0836788874167067	[263]	[504]	0	hSpCas9	negative selection	11235955
112454659	112454682	12	+	28162770	OCIAML5	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-3.917022012704767	[158]	[18]	-9	hSpCas9	negative selection	11235956
112450499	112450522	12	-	28162770	OCIAML5	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-1.77651553785682	[278]	[146]	-7	hSpCas9	negative selection	11235957
112456042	112456065	12	+	28162770	OCIAML5	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	0.017793293799554633	[341]	[624]	0	hSpCas9	negative selection	11235958
112446377	112446400	12	+	28162770	OCIAML5	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-2.1529330502235298	[509]	[206]	-8	hSpCas9	negative selection	11235959
112453301	112453324	12	+	28162770	OCIAML5	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.2711219731042216	[487]	[1062]	2	hSpCas9	negative selection	11235960
112419104	112419127	12	+	28162770	EOL1	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-5.294620748891627	[148]	[1]	-9	hSpCas9	negative selection	11405317
112502237	112502260	12	-	28162770	EOL1	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	0.5619776921858263	[125]	[97]	5	hSpCas9	negative selection	11405318
112486476	112486499	12	+	28162770	EOL1	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-0.3926424043101646	[151]	[60]	-3	hSpCas9	negative selection	11405319
112453315	112453338	12	+	28162770	EOL1	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	-3.7909462922928467	[288]	[10]	-9	hSpCas9	negative selection	11405320
112486527	112486550	12	+	28162770	EOL1	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	-0.2097533201410564	[1079]	[491]	-1	hSpCas9	negative selection	11405321
112454659	112454682	12	+	28162770	EOL1	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-2.5425782388567635	[375]	[33]	-8	hSpCas9	negative selection	11405322
112450499	112450522	12	-	28162770	EOL1	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-1.8568119419541251	[384]	[55]	-8	hSpCas9	negative selection	11405323
112456042	112456065	12	+	28162770	EOL1	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	-0.09829220478757672	[572]	[281]	0	hSpCas9	negative selection	11405324
112446377	112446400	12	+	28162770	EOL1	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-1.4995919348155617	[847]	[157]	-7	hSpCas9	negative selection	11405325
112453301	112453324	12	+	28162770	EOL1	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.735634669747919	[716]	[628]	6	hSpCas9	negative selection	11405326
112419104	112419127	12	+	28162770	MOLM13	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-3.1061020013555747	[130]	[10]	-8	hSpCas9	negative selection	11574683
112502237	112502260	12	-	28162770	MOLM13	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	-0.9354663126866297	[163]	[61]	-5	hSpCas9	negative selection	11574684
112486476	112486499	12	+	28162770	MOLM13	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-5.232550336596514	[103]	[1]	-9	hSpCas9	negative selection	11574685
112453315	112453338	12	+	28162770	MOLM13	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	-3.6195734597057605	[237]	[13]	-9	hSpCas9	negative selection	11574686
112486527	112486550	12	+	28162770	MOLM13	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.0876173004264118	[819]	[629]	0	hSpCas9	negative selection	11574687
112454659	112454682	12	+	28162770	MOLM13	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.9163229915971263	[354]	[135]	-5	hSpCas9	negative selection	11574688
112450499	112450522	12	-	28162770	MOLM13	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.3723869298639232	[409]	[228]	-2	hSpCas9	negative selection	11574689
112456042	112456065	12	+	28162770	MOLM13	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	-0.18210400053462528	[691]	[440]	-1	hSpCas9	negative selection	11574690
112446377	112446400	12	+	28162770	MOLM13	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-1.2464384089418956	[1095]	[333]	-6	hSpCas9	negative selection	11574691
112453301	112453324	12	+	28162770	MOLM13	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.9934189687465771	[891]	[1283]	7	hSpCas9	negative selection	11574692
112419104	112419127	12	+	28162770	HEL	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-2.0296865099711385	[101]	[15]	-8	hSpCas9	negative selection	11744049
112502237	112502260	12	-	28162770	HEL	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	-0.2298818615234155	[129]	[70]	-2	hSpCas9	negative selection	11744050
112486476	112486499	12	+	28162770	HEL	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-2.4503705723911247	[127]	[14]	-8	hSpCas9	negative selection	11744051
112453315	112453338	12	+	28162770	HEL	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	-0.8694673262854852	[173]	[60]	-5	hSpCas9	negative selection	11744052
112486527	112486550	12	+	28162770	HEL	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.1260456072962295	[680]	[475]	1	hSpCas9	negative selection	11744053
112454659	112454682	12	+	28162770	HEL	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-1.4893647040069884	[319]	[72]	-7	hSpCas9	negative selection	11744054
112450499	112450522	12	-	28162770	HEL	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-1.7550206758466516	[331]	[62]	-7	hSpCas9	negative selection	11744055
112456042	112456065	12	+	28162770	HEL	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	-0.5316145286681755	[570]	[252]	-4	hSpCas9	negative selection	11744056
112446377	112446400	12	+	28162770	HEL	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-2.822575343373826	[982]	[88]	-8	hSpCas9	negative selection	11744057
112453301	112453324	12	+	28162770	HEL	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.38509768493678154	[800]	[669]	3	hSpCas9	negative selection	11744058
112419104	112419127	12	+	28162770	MV411	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-5.902309568721907	[70]	[0]	-9	hSpCas9	negative selection	11913415
112502237	112502260	12	-	28162770	MV411	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	-1.2413096346790775	[86]	[30]	-7	hSpCas9	negative selection	11913416
112486476	112486499	12	+	28162770	MV411	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-0.6291800337119426	[111]	[60]	-4	hSpCas9	negative selection	11913417
112453315	112453338	12	+	28162770	MV411	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	-0.892287212883838	[129]	[58]	-6	hSpCas9	negative selection	11913418
112486527	112486550	12	+	28162770	MV411	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.5148503971271432	[657]	[791]	4	hSpCas9	negative selection	11913419
112454659	112454682	12	+	28162770	MV411	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-1.4083462871280776	[166]	[52]	-7	hSpCas9	negative selection	11913420
112450499	112450522	12	-	28162770	MV411	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-0.997674947053756	[255]	[107]	-6	hSpCas9	negative selection	11913421
112456042	112456065	12	+	28162770	MV411	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	0.36720587725292875	[438]	[476]	3	hSpCas9	negative selection	11913422
112446377	112446400	12	+	28162770	MV411	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-1.3755811762004564	[652]	[211]	-7	hSpCas9	negative selection	11913423
112453301	112453324	12	+	28162770	MV411	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.5527546828252223	[593]	[733]	5	hSpCas9	negative selection	11913424
112419104	112419127	12	+	28162770	MONOMAC1	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-0.651602710525035	[36]	[26]	-5	hSpCas9	negative selection	12082781
112502237	112502260	12	-	28162770	MONOMAC1	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	-0.5135105118548081	[65]	[52]	-4	hSpCas9	negative selection	12082782
112486476	112486499	12	+	28162770	MONOMAC1	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-4.536886849944178	[80]	[3]	-9	hSpCas9	negative selection	12082783
112453315	112453338	12	+	28162770	MONOMAC1	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	-2.3535413327395447	[106]	[23]	-9	hSpCas9	negative selection	12082784
112486527	112486550	12	+	28162770	MONOMAC1	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	-0.7974293883503157	[375]	[247]	-6	hSpCas9	negative selection	12082785
112454659	112454682	12	+	28162770	MONOMAC1	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-1.5798939405892476	[132]	[50]	-8	hSpCas9	negative selection	12082786
112450499	112450522	12	-	28162770	MONOMAC1	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	-1.058209142362237	[197]	[108]	-7	hSpCas9	negative selection	12082787
112456042	112456065	12	+	28162770	MONOMAC1	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	-0.6184158732122244	[303]	[226]	-5	hSpCas9	negative selection	12082788
112446377	112446400	12	+	28162770	MONOMAC1	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.6589409513763718	[437]	[317]	-5	hSpCas9	negative selection	12082789
112453301	112453324	12	+	28162770	MONOMAC1	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.2706879783772289	[409]	[566]	2	hSpCas9	negative selection	12082790
112419104	112419127	12	+	28162770	OCIAML2	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-0.742709370678962	[15]	[52]	-5	hSpCas9	negative selection	12252147
112502237	112502260	12	-	28162770	OCIAML2	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	0.1770684308269579	[14]	[93]	1	hSpCas9	negative selection	12252148
112486476	112486499	12	+	28162770	OCIAML2	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-1.286205254104734	[21]	[49]	-7	hSpCas9	negative selection	12252149
112453315	112453338	12	+	28162770	OCIAML2	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	0.012453061459781423	[21]	[122]	0	hSpCas9	negative selection	12252150
112486527	112486550	12	+	28162770	OCIAML2	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.47278664639147117	[103]	[799]	4	hSpCas9	negative selection	12252151
112454659	112454682	12	+	28162770	OCIAML2	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	1.1284078606907177	[33]	[411]	9	hSpCas9	negative selection	12252152
112450499	112450522	12	-	28162770	OCIAML2	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.11808481034010254	[63]	[384]	1	hSpCas9	negative selection	12252153
112456042	112456065	12	+	28162770	OCIAML2	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	0.38104742780073764	[86]	[627]	3	hSpCas9	negative selection	12252154
112446377	112446400	12	+	28162770	OCIAML2	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	0.5096647654102799	[128]	[1017]	5	hSpCas9	negative selection	12252155
112453301	112453324	12	+	28162770	OCIAML2	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.45656486682144615	[126]	[965]	4	hSpCas9	negative selection	12252156
112419104	112419127	12	+	28162770	OCIAML3	viability	GGAGGAACATGACATCGCGGAGG	PTPN11	ENSG00000179295	-0.13006054056437288	[28]	[79]	-1	hSpCas9	negative selection	12421513
112502237	112502260	12	-	28162770	OCIAML3	viability	TACTCTGCACAGGGTGGCGTTGG	PTPN11	ENSG00000179295	2.174176684452763	[15]	[217]	9	hSpCas9	negative selection	12421514
112486476	112486499	12	+	28162770	OCIAML3	viability	GGAATACGGAGAGAACGGTCTGG	PTPN11	ENSG00000179295	-1.4420045468791132	[44]	[49]	-7	hSpCas9	negative selection	12421515
112453315	112453338	12	+	28162770	OCIAML3	viability	GCGCACTGGTGATGACAAAGGGG	PTPN11	ENSG00000179295	-0.2482328034824332	[47]	[121]	-2	hSpCas9	negative selection	12421516
112486527	112486550	12	+	28162770	OCIAML3	viability	ACGGCGTGCCCAGCGACCCTGGG	PTPN11	ENSG00000179295	0.5979791236479284	[136]	[625]	5	hSpCas9	negative selection	12421517
112454659	112454682	12	+	28162770	OCIAML3	viability	TACAGTACTACAACTCAAGCAGG	PTPN11	ENSG00000179295	-0.634649624821509	[71]	[139]	-5	hSpCas9	negative selection	12421518
112450499	112450522	12	-	28162770	OCIAML3	viability	GTTACTGACCTTTCAGAGGTAGG	PTPN11	ENSG00000179295	0.2880666351131461	[85]	[316]	2	hSpCas9	negative selection	12421519
112456042	112456065	12	+	28162770	OCIAML3	viability	AGGCTTTTGGGAAGAATTTGAGG	PTPN11	ENSG00000179295	0.2203168365482826	[117]	[414]	2	hSpCas9	negative selection	12421520
112446377	112446400	12	+	28162770	OCIAML3	viability	GAGACTTCACACTTTCCGTTAGG	PTPN11	ENSG00000179295	-0.04146661729538459	[179]	[527]	0	hSpCas9	negative selection	12421521
112453301	112453324	12	+	28162770	OCIAML3	viability	TTTGTTCTTTCTGTGCGCACTGG	PTPN11	ENSG00000179295	0.8497252919551463	[167]	[913]	7	hSpCas9	negative selection	12421522